Single-state electronic ballast with dimming feature and unity power factor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, T.F.; Yu, T.H.; Chiang, M.C.

1998-05-01

Analysis, design, and practical consideration of a single-stage electronic ballast with dimming feature and unity power factor are presented in this paper. The proposed single-stage ballast is the combination of a boost converter and a half-bridge series-resonant parallel-loaded inverter. The boost semistage working in the discontinuous conduction mode functions as a power factor corrector and the inverter semistage operated above resonance are employed to ballast the lamp. Replacing the lamp with the plasma model, analysis of the ballast is fulfilled. The dimming feature is carried out by pulse-width modulation (PWM) and variable-frequency controls simultaneously. The proposed single-stage ballast is suitablemore » for applications with moderate power level and low-line voltage while requiring a high-output voltage. It can save a controller, an active switch and its driver, reduce size, and possibly increase system reliability while requiring two additional diodes over a conventional two-stage system. A prototype was implemented to verify the theoretical discussion. The hardware measurements have shown that the desired performance can be achieved feasibly.« less

Computer simulations of optimum boost and buck-boost converters

NASA Technical Reports Server (NTRS)

Rahman, S.

1982-01-01

The development of mathematicl models suitable for minimum weight boost and buck-boost converter designs are presented. The facility of an augumented Lagrangian (ALAG) multiplier-based nonlinear programming technique is demonstrated for minimum weight design optimizations of boost and buck-boost power converters. ALAG-based computer simulation results for those two minimum weight designs are discussed. Certain important features of ALAG are presented in the framework of a comprehensive design example for boost and buck-boost power converter design optimization. The study provides refreshing design insight of power converters and presents such information as weight annd loss profiles of various semiconductor components and magnetics as a function of the switching frequency.

Nonlinear program based optimization of boost and buck-boost converter designs

NASA Astrophysics Data System (ADS)

Rahman, S.; Lee, F. C.

The facility of an Augmented Lagrangian (ALAG) multiplier based nonlinear programming technique is demonstrated for minimum-weight design optimizations of boost and buck-boost power converters. Certain important features of ALAG are presented in the framework of a comprehensive design example for buck-boost power converter design optimization. The study provides refreshing design insight of power converters and presents such information as weight and loss profiles of various semiconductor components and magnetics as a function of the switching frequency.

Symmetry boost of the fidelity of Shor factoring

NASA Astrophysics Data System (ADS)

Nam, Y. S.; Blümel, R.

2018-05-01

In Shor's algorithm quantum subroutines occur with the structure F U F-1 , where F is a unitary transform and U is performing a quantum computation. Examples are quantum adders and subunits of quantum modulo adders. In this paper we show, both analytically and numerically, that if, in analogy to spin echoes, F and F-1 can be implemented symmetrically when executing Shor's algorithm on actual, imperfect quantum hardware, such that F and F-1 have the same hardware errors, a symmetry boost in the fidelity of the combined F U F-1 quantum operation results when compared to the case in which the errors in F and F-1 are independently random. Running the complete gate-by-gate implemented Shor algorithm, we show that the symmetry-induced fidelity boost can be as large as a factor 4. While most of our analytical and numerical results concern the case of over- and under-rotation of controlled rotation gates, in the numerically accessible case of Shor's algorithm with a small number of qubits, we show explicitly that the symmetry boost is robust with respect to more general types of errors. While, expectedly, additional error types reduce the symmetry boost, we show explicitly, by implementing general off-diagonal SU (N ) errors (N =2 ,4 ,8 ), that the boost factor scales like a Lorentzian in δ /σ , where σ and δ are the error strengths of the diagonal over- and underrotation errors and the off-diagonal SU (N ) errors, respectively. The Lorentzian shape also shows that, while the boost factor may become small with increasing δ , it declines slowly (essentially like a power law) and is never completely erased. We also investigate the effect of diagonal nonunitary errors, which, in analogy to unitary errors, reduce but never erase the symmetry boost. Going beyond the case of small quantum processors, we present analytical scaling results that show that the symmetry boost persists in the practically interesting case of a large number of qubits. We illustrate this result explicitly for the case of Shor factoring of the semiprime RSA-1024, where, analytically, focusing on over- and underrotation errors, we obtain a boost factor of about 10. In addition, we provide a proof of the fidelity product formula, including its range of applicability.

Modified Perfect Harmonics Cancellation Control of a Grid Interfaced SPV Power Generation

NASA Astrophysics Data System (ADS)

Singh, B.; Shahani, D. T.; Verma, A. K.

2015-03-01

This paper deals with a grid interfaced solar photo voltaic (SPV) power generating system with modified perfect harmonic cancellation (MPHC) control for power quality improvement in terms of mitigation of the current harmonics, power factor correction, control of point of common coupling (PCC) voltage with reactive power compensation and load balancing in a three phase distribution system. The proposed grid interfaced SPV system consists of a SPV array, a dc-dc boost converter and a voltage source converter (VSC) used for the compensation of other connected linear and nonlinear loads at PCC. The reference grid currents are estimated using MPHC method and control signals are derived by using pulse width modulation (PWM) current controller of VSC. The SPV power is fed to the common dc bus of VSC and dc-dc boost converter using maximum power point tracking (MPPT). The dc link voltage of VSC is regulated by using dc voltage proportional integral (PI) controller. The analysis of the proposed SPV power generating system is carried out under dc/ac short circuit and severe SPV-SX and SPV-TX intrusion.

Assessment of MCRM Boost Assist from Orbit for Deep Space Missions

NASA Technical Reports Server (NTRS)

2000-01-01

Report provides results of analysis for the beamed energy driven MHD Chemical Rocket Motor (MCRM) for application to boost from orbit to escape for deep space and interplanetary missions. Parametric analyses were performed in the mission to determine operating regime for which the MCRM provides significant propulsion performance enhancement. Analysis of the MHD accelerator was performed numerical computational methods to determine design and operational features necessary to achieve Isp on the order of 2,000 to 3,000 seconds. Algorithms were developed to scale weights for the accelerator and power supply. Significant improvement in propulsion system performance can be achieved with the beamed energy driven MCRM. The limiting factor on achievable vehicle acceleration is the specific power of the rectenna.

CMOS single-stage input-powered bridge rectifier with boost switch and duty cycle control

NASA Astrophysics Data System (ADS)

Radzuan, Roskhatijah; Mohd Salleh, Mohd Khairul; Hamzah, Mustafar Kamal; Ab Wahab, Norfishah

2017-06-01

This paper presents a single-stage input-powered bridge rectifier with boost switch for wireless-powered devices such as biomedical implants and wireless sensor nodes. Realised using CMOS process technology, it employs a duty cycle switch control to achieve high output voltage using boost technique, leading to a high output power conversion. It has only six external connections with the boost inductance. The input frequency of the bridge rectifier is set at 50 Hz, while the switching frequency is 100 kHz. The proposed circuit is fabricated on a single 0.18-micron CMOS die with a space area of 0.024 mm2. The simulated and measured results show good agreement.

Distributed photovoltaic architecture powering a DC bus: Impact of duty cycle and load variations on the efficiency of the generator

NASA Astrophysics Data System (ADS)

Allouache, Hadj; Zegaoui, Abdallah; Boutoubat, Mohamed; Bokhtache, Aicha Aissa; Kessaissia, Fatma Zohra; Charles, Jean-Pierre; Aillerie, Michel

2018-05-01

This paper focuses on a photovoltaic generator feeding a load via a boost converter in a distributed PV architecture. The principal target is the evaluation of the efficiency of a distributed photovoltaic architecture powering a direct current (DC) PV bus. This task is achieved by outlining an original way for tracking the Maximum Power Point (MPP) taking into account load variations and duty cycle on the electrical quantities of the boost converter and on the PV generator output apparent impedance. Thereafter, in a given sized PV system, we analyze the influence of the load variations on the behavior of the boost converter and we deduce the limits imposed by the load on the DC PV bus. The simultaneous influences of 1- the variation of the duty cycle of the boost converter and 2- the load power on the parameters of the various components of the photovoltaic chain and on the boost performances are clearly presented as deduced by simulation.

Energy Harvesting from Salinity Gradient

NASA Astrophysics Data System (ADS)

Muhthassim, B.; Thian, X. K.; Hasan, K. N. Md

2018-04-01

Abstract: Energy harvesting from salt water received attention started back in 1970s’, but due to varying interests in the field and the growing potentials of other more promising sources, more work was required to fully establish it. This paper aims at identifying existing techniques of energy harvesting and the methodology involved determining an effective technique for small scale applications of the method. Capacitive deionization technique which involves electrochemical reaction was chosen for further analysis. The experiment was conducted to analyze factors affecting its performance including the electrode and the electrolyte. Combination electrode of carbon/aluminium, copper/aluminium and carbon/copper were selected and tested with different concentration of salty water. From the experiment, copper and aluminum electrodes were found to be the most effective among the rest. A DC-DC boost converter was used to step-up the voltage. Physical implementation of the circuit was done and the circuit was tested in which an input voltage of 1.022 V was boosted to 1.255 V. The efficiency of the boost converter was 38.17 % based on input power and output power obtained.

Maximum power point tracking techniques for wind energy systems using three levels boost converter

NASA Astrophysics Data System (ADS)

Tran, Cuong Hung; Nollet, Frédéric; Essounbouli, Najib; Hamzaoui, Abdelaziz

2018-05-01

This paper presents modeling and simulation of three level Boost DC-DC converter in Wind Energy Conversion System (WECS). Three-level Boost converter has significant advantage compared to conventional Boost. A maximum power point tracking (MPPT) method for a variable speed wind turbine using permanent magnet synchronous generator (PMSG) is also presented. Simulation of three-level Boost converter topology with Perturb and Observe algorithm and Fuzzy Logic Control is implemented in MATLAB/SIMULINK. Results of this simulation show that the system with MPPT using fuzzy logic controller has better performance to the Perturb and Observe algorithm: fast response under changing conditions and small oscillation.

Development and Testing of an Ultra Low Power System-On-Chip (SOC) Platform for Marine Mammal Tags and Passive Acoustic Signal Processing

DTIC Science & Technology

2014-09-30

current (3-5mA). The system can harvest 16 power from a DC input source like a thermoelectric generator (TEG) or photovoltaic cell (PV). The boost...results from components to report. Designed for thermoelectric energy harvesting in 130nm CMOS, the boost converter reduces the achievable input...harvesting. The boost converter further incorporates maximum power point tracking for harvesting from both thermoelectric generators (TEGs) and solar

Observer-based higher order sliding mode control of power factor in three-phase AC/DC converter for hybrid electric vehicle applications

NASA Astrophysics Data System (ADS)

Liu, Jianxing; Laghrouche, Salah; Wack, Maxime

2014-06-01

In this paper, a full-bridge boost power converter topology is studied for power factor control, using output higher order sliding mode control. The AC/DC converters are used for charging the battery and super-capacitor in hybrid electric vehicles from the utility. The proposed control forces the input currents to track the desired values, which can control the output voltage while keeping the power factor close to one. Super-twisting sliding mode observer is employed to estimate the input currents and load resistance only from the measurement of output voltage. Lyapunov analysis shows the asymptotic convergence of the closed-loop system to zero. Multi-rate simulation illustrates the effectiveness and robustness of the proposed controller in the presence of measurement noise.

High Temperature Boost (HTB) Power Processing Unit (PPU) Formulation Study

NASA Technical Reports Server (NTRS)

Chen, Yuan; Bradley, Arthur T.; Iannello, Christopher J.; Carr, Gregory A.; Mohammad, Mojarradi M.; Hunter, Don J.; DelCastillo, Linda; Stell, Christopher B.

2013-01-01

This technical memorandum is to summarize the Formulation Study conducted during fiscal year 2012 on the High Temperature Boost (HTB) Power Processing Unit (PPU). The effort is authorized and supported by the Game Changing Technology Division, NASA Office of the Chief Technologist. NASA center participation during the formulation includes LaRC, KSC and JPL. The Formulation Study continues into fiscal year 2013. The formulation study has focused on the power processing unit. The team has proposed a modular, power scalable, and new technology enabled High Temperature Boost (HTB) PPU, which has 5-10X improvement in PPU specific power/mass and over 30% in-space solar electric system mass saving.

A modular electric power system test bed for small spacecraft

NASA Technical Reports Server (NTRS)

Button, Robert M.; Baez, Anastacio N.

1994-01-01

In the new climate of smaller, faster, and cheaper space science satellites, a new power system topology has been developed at the NASA Lewis Research Center. This new topology is based on a series connected boost converter (SCBC) and can greatly affect the size, weight, fault tolerance, and cost of any small spacecraft using photovoltaic solar arrays. The paper presents electric power system design factors and requirements as background information. The series connected boost converter topology is discussed and several advantages over existing technologies are illustrated. Besides being small, lightweight, and efficient, this topology has the added benefit of inherent fault tolerance. A positive ground power system test bed has been developed for the TROPIX spacecraft program. Performance of the SCBC in the test bed is described in detail. SCBC efficiencies of 95 percent to 98 percent have been measured. Finally, a modular, photovoltaic regulator 'kit' concept is presented. Two SCBC's are used to regulate solar array charging of batteries and to provide 'utilitytype' power to the user loads. The kit's modularity will allow a spacecraft electric power system to be built from off-the-shelf hardware; resulting in smaller, faster, and cheaper spacecraft.

Analytic boosted boson discrimination

DOE PAGES

Larkoski, Andrew J.; Moult, Ian; Neill, Duff

2016-05-20

Observables which discriminate boosted topologies from massive QCD jets are of great importance for the success of the jet substructure program at the Large Hadron Collider. Such observables, while both widely and successfully used, have been studied almost exclusively with Monte Carlo simulations. In this paper we present the first all-orders factorization theorem for a two-prong discriminant based on a jet shape variable, D 2, valid for both signal and background jets. Our factorization theorem simultaneously describes the production of both collinear and soft subjets, and we introduce a novel zero-bin procedure to correctly describe the transition region between thesemore » limits. By proving an all orders factorization theorem, we enable a systematically improvable description, and allow for precision comparisons between data, Monte Carlo, and first principles QCD calculations for jet substructure observables. Using our factorization theorem, we present numerical results for the discrimination of a boosted Z boson from massive QCD background jets. We compare our results with Monte Carlo predictions which allows for a detailed understanding of the extent to which these generators accurately describe the formation of two-prong QCD jets, and informs their usage in substructure analyses. In conclusion, our calculation also provides considerable insight into the discrimination power and calculability of jet substructure observables in general.« less

Hyperdynamics boost factor achievable with an ideal bias potential

DOE PAGES

Huang, Chen; Perez, Danny; Voter, Arthur F.

2015-08-20

Hyperdynamics is a powerful method to significantly extend the time scales amenable to molecular dynamics simulation of infrequent events. One outstanding challenge, however, is the development of the so-called bias potential required by the method. In this work, we design a bias potential using information about all minimum energy pathways (MEPs) out of the current state. While this approach is not suitable for use in an actual hyperdynamics simulation, because the pathways are generally not known in advance, it allows us to show that it is possible to come very close to the theoretical boost limit of hyperdynamics while maintainingmore » high accuracy. We demonstrate this by applying this MEP-based hyperdynamics (MEP-HD) to metallic surface diffusion systems. In most cases, MEP-HD gives boost factors that are orders of magnitude larger than the best existing bias potential, indicating that further development of hyperdynamics bias potentials could have a significant payoff. Lastly, we discuss potential practical uses of MEP-HD, including the possibility of developing MEP-HD into a true hyperdynamics.« less

Volunteering within Initial Teacher Education: Factors That Boost and Block Participation

ERIC Educational Resources Information Center

Forster, Daniella J.; Archer, Jennifer; Tajin, Rukhsana T.

2015-01-01

Voluntary professional experience can be a powerful way for initial teacher education (ITE) students to develop an understanding of schools and their communities. Do ITE students make use of these opportunities? There is little Australian research that explores genuine volunteering that does not "require" students to engage with the…

Unity power factor switching regulator

NASA Technical Reports Server (NTRS)

Rippel, Wally E. (Inventor)

1983-01-01

A single or multiphase boost chopper regulator operating with unity power factor, for use such as to charge a battery is comprised of a power section for converting single or multiphase line energy into recharge energy including a rectifier (10), one inductor (L.sub.1) and one chopper (Q.sub.1) for each chopper phase for presenting a load (battery) with a current output, and duty cycle control means (16) for each chopper to control the average inductor current over each period of the chopper, and a sensing and control section including means (20) for sensing at least one load parameter, means (22) for producing a current command signal as a function of said parameter, means (26) for producing a feedback signal as a function of said current command signal and the average rectifier voltage output over each period of the chopper, means (28) for sensing current through said inductor, means (18) for comparing said feedback signal with said sensed current to produce, in response to a difference, a control signal applied to the duty cycle control means, whereby the average inductor current is proportionate to the average rectifier voltage output over each period of the chopper, and instantaneous line current is thereby maintained proportionate to the instantaneous line voltage, thus achieving a unity power factor. The boost chopper is comprised of a plurality of converters connected in parallel and operated in staggered phase. For optimal harmonic suppression, the duty cycles of the switching converters are evenly spaced, and by negative coupling between pairs 180.degree. out-of-phase, peak currents through the switches can be reduced while reducing the inductor size and mass.

Anisotropies of the cosmic microwave background in nonstandard cold dark matter models

NASA Technical Reports Server (NTRS)

Vittorio, Nicola; Silk, Joseph

1992-01-01

Small angular scale cosmic microwave anisotropies in flat, vacuum-dominated, cold dark matter cosmological models which fit large-scale structure observations and are consistent with a high value for the Hubble constant are reexamined. New predictions for CDM models in which the large-scale power is boosted via a high baryon content and low H(0) are presented. Both classes of models are consistent with current limits: an improvement in sensitivity by a factor of about 3 for experiments which probe angular scales between 7 arcmin and 1 deg is required, in the absence of very early reionization, to test boosted CDM models for large-scale structure formation.

New Solar Cells to Boost Satellite Power

Science.gov Websites

New Solar Cells to Boost Satellite Power For more information contact: George Douglas (303) 275 much as doubled, each satellite and its services can be more economical and offer a greater return to satellite customers. The new cells will also have a longer useful life. Because of their construction they

Analysis and design of a high power, digitally-controlled spacecraft power system

NASA Technical Reports Server (NTRS)

Lee, F. C.; Cho, B. H.

1990-01-01

The progress to date on the analysis and design of a high power, digitally controlled spacecraft power system is described. Several battery discharger topologies were compared for use in the space platform application. Updated information has been provided on the battery voltage specification. Initially it was thought to be in the 30 to 40 V range. It is now specified to be 53 V to 84 V. This eliminated the tapped-boost and the current-fed auto-transformer converters from consideration. After consultations with NASA, it was decided to trade-off the following topologies: (1) boost converter; (2) multi-module, multi-phase boost converter; and (3) voltage-fed push-pull with auto-transformer. A non-linear design optimization software tool was employed to facilitate an objective comparison. Non-linear design optimization insures that the best design of each topology is compared. The results indicate that a four-module, boost converter with each module operating 90 degrees out of phase is the optimum converter for the space platform. Large-signal and small-signal models were generated for the shunt, charger, discharger, battery, and the mode controller. The models were first tested individually according to the space platform power system specifications supplied by NASA. The effect of battery voltage imbalance on parallel dischargers was investigated with respect to dc and small-signal responses. Similarly, the effects of paralleling dischargers and chargers were also investigated. A solar array and shunt model was included in these simulations. A model for the bus mode controller (power control unit) was also developed to interface the Orbital replacement Unit (ORU) model to the platform power system. Small signal models were used to generate the bus impedance plots in the various operating modes. The large signal models were integrated into a system model, and time domain simulations were performed to verify bus regulation during mode transitions. Some changes have subsequently been incorporated into the models. The changes include the use of a four module boost discharger, and a new model for the mode controller, which includes the effects of saturation. The new simulations for the boost discharger show the improvement in bus ripple that can be achieved by phase-shifted operation of each of the boost modules.

Enhancement of thermoelectric characteristics in AlGaN/GaN films deposited on inverted pyramidal Si surfaces

NASA Astrophysics Data System (ADS)

Yalamarthy, Ananth Saran; So, Hongyun; Senesky, Debbie G.

2017-07-01

In this letter, we demonstrate an engineering strategy to boost thermoelectric power factor via geometry-induced properties of the pyramid structure. Aluminum gallium nitride (AlGaN)/GaN heterostructured films grown on inverted pyramidal silicon (Si) demonstrate higher power factor as compared to those grown on conventional flat Si substrates. We found that the magnitude of the Seebeck coefficient at room temperature increased from approximately 297 μVK-1 for the flat film to approximately 849 μVK-1 for the film on inverted pyramidal Si. In addition, the "effective" electrical conductivity of the AlGaN/GaN on the inverted pyramidal structure increased compared to the flat structure, generating an enhancement of thermoelectric power factor. The results demonstrate how manipulation of geometry can be used to achieve better thermoelectric characteristics in a manner that could be scaled to a variety of different material platforms.

Modeling and Analysis of Power Processing Systems (MAPPS). Volume 2: Appendices

NASA Technical Reports Server (NTRS)

Lee, F. C.; Radman, S.; Carter, R. A.; Wu, C. H.; Yu, Y.; Chang, R.

1980-01-01

The computer programs and derivations generated in support of the modeling and design optimization program are presented. Programs for the buck regulator, boost regulator, and buck-boost regulator are described. The computer program for the design optimization calculations is presented. Constraints for the boost and buck-boost converter were derived. Derivations of state-space equations and transfer functions are presented. Computer lists for the converters are presented, and the input parameters justified.

Modelling, Simulation and Construction of a DC/DC Boost Power Converter: A School Experimental System

ERIC Educational Resources Information Center

Silva-Ortigoza, R.; Silva-Ortigoza, G.; Hernandez-Guzman, V. M.; Saldana-Gonzalez, G.; Marcelino-Aranda, M.; Marciano-Melchor, M.

2012-01-01

We introduce a dc/dc boost power converter as a didactic prototype intended to support courses on electric circuit analysis experimentally. The corresponding mathematical model is obtained, the converter is designed and an experimental setup is described, constructed and tested. Simplicity of construction as well as low cost of components renders…

Series Connected Buck-Boost Regulator

NASA Technical Reports Server (NTRS)

Birchenough, Arthur G. (Inventor)

2006-01-01

A Series Connected Buck-Boost Regulator (SCBBR) that switches only a fraction of the input power, resulting in relatively high efficiencies. The SCBBR has multiple operating modes including a buck, a boost, and a current limiting mode, so that an output voltage of the SCBBR ranges from below the source voltage to above the source voltage.

An Advanced Photovoltaic Array Regulator Module

NASA Technical Reports Server (NTRS)

Button, Robert M.

1996-01-01

Current trends in satellite design are focused on developing small, reliable, and inexpensive spacecraft. To that end, a modular power management and distribution system is proposed which will help transition the aerospace industry towards an assembly line approach to building spacecraft. The modular system is based on an innovative DC voltage boost converter called the Series Connected Boost Unit (SCBU). The SCBU uses any isolating DC-DC converter and adds a unique series connection. This simple modification provides the SCBU topology with many advantages over existing boost converters. Efficiencies of 94-98%, power densities above 1,000 W/kg, and inherent fault tolerance are just a few of the characteristics presented. Limitations of the SCBU technology are presented, and it is shown that the SCBU makes an ideal photovoltaic an-ay regulator. A set of photovoltaic power system requirements are presented that can be applied to almost any low Earth orbit satellite. Finally, a modular design based on the series connected boost unit is outlined and functional descriptions of the components are given.

Energy Beam Highways Through the Skies

NASA Technical Reports Server (NTRS)

Myrabo, Leik N.

1996-01-01

The emergence of Energy Beam Flight Transportation Systems could dramatically change the way we travel in the 21st Century. A framework for formulating 'Highways of Light' and the top level architectures that invoke radically new Space Power Grid infrastructure, are introduced. Basically, such flight systems, hereafter called Lightcraft, would employ off-board energy beam sources (either laser or microwave) to energize on-board dependent 'motors' -- instead of the traditional autonomous 'engines' with their on-board energy sources (e.g., chemical fuels). Extreme reductions in vehicle dry mass appear feasible with the use of off-board power and a high degree of on-board artificial intelligence. Such vehicles may no longer need airports for refueling (since they require no propellant), and could possibly pick up travelers at their homes -- before motoring over to one of many local boost stations, for the flight out. With off-board power, hyper-energetic acceleration performance and boost-glide trajectories become feasible. Hypersonic MS airbreathing propulsion can enable boosts up to twice escape velocity, which will cut trip times to the moon down to 5.5 hours. The predominant technological, environmental and social factors that will result from such transportation systems will be stressed. This presentation first introduces the remote source siting options for the space power system infrastructure, and then provides three representative laser/microwave Lightcraft options (derived from historical Case Studies): i.e., 'Acorn', 'Toy Top', and 'Disc.' Next the gamut of combined-cycle engine options developed for these Lightcraft are examined -- to illuminate the 'emerging technologies' that must be harnessed to produce flight hardware. Needed proof-of concept experiments are identified, along with the Macro-Level Issues that can springboard these revolutionary concepts into hardware reality.

Grid-connected wind and photovoltaic system

NASA Astrophysics Data System (ADS)

Devabakthuni, Sindhuja

The objective of this thesis is to design a grid connected wind and photovoltaic system. A new model of converter control was designed which maintains the voltage of the bus to grid as constant when combined system of solar and wind is connected to AC bus. The model is designed to track maximum power at each point irrespective of changes in irradiance, temperature and wind speed which affects the power supplied to grid. Solar power from the sun is not constant as it is affected by changes in irradiances and temperature. Even the wind power is affected by wind speed. A MPPT controller was designed for both systems. A boost converter is designed which uses the pulses from MPPT controller to boost the output. Wind system consists of wind turbine block from the MATLAB with a pitch angle controller to maintain optimum pitch angle. The output from wind turbine is connected to a permanent magnet synchronous generator. The unregulated DC output from the photovoltaic system is directly given to boost converter. The AC output from the wind system is given to an uncontrolled rectifier to get a unregulated DC output. The unregulated DC output goes to the boost converter. A voltage source inverter was designed which converts the rectified DC output from the boost converter to AC power. The inverter is designed to maintain constant AC bus voltage irrespective of the disturbances in the power supply. Photovoltaic and wind systems are individually designed for 5KW each in MATLAB-Simulink environment. In this thesis, the models were subjected to changes in irradiance, temperature and wind speed and the results were interpreted. The model was successful in tracking maximum at every instant and the AC bus voltage was maintained constant throughout the simulation.

A PIPO Boost Converter with Low Ripple and Medium Current Application

NASA Astrophysics Data System (ADS)

Bandri, S.; Sofian, A.; Ismail, F.

2018-04-01

This paper presents a Parallel Input Parallel Output (PIPO) boost converter is proposed to gain power ability of converter, and reduce current inductors. The proposed technique will distribute current for n-parallel inductor and switching component. Four parallel boost converters implement on input voltage 20.5Vdc to generate output voltage 28.8Vdc. The PIPO boost converter applied phase shift pulse width modulation which will compare with conventional PIPO boost converters by using a similar pulse for every switching component. The current ripple reduction shows an advantage PIPO boost converter then conventional boost converter. Varies loads and duty cycle will be simulated and analyzed to verify the performance of PIPO boost converter. Finally, the unbalance of current inductor is able to be verified on four area of duty cycle in less than 0.6.

Design and dSpace interfacing of current fed high gain dc to dc boost converter for low voltage applications

NASA Astrophysics Data System (ADS)

Mukhopadhyay, Debraj; Das, Subhrajit; Arunkumar, G.; Elangovan, D.; Ragunath, G.

2017-11-01

In this paper a current fed interleaved DC - DC boost converter which has an isolated topology and used for high voltage step up is proposed. A basic DC to DC boost converter converts uncontrolled DC voltage into controlled DC voltage of higher magnitude. Whereas this topology has the advantages of lower input current ripple, lesser output voltage, lesser stress on switches, faster transient response, improved reliability and much lesser electromagnetic emission over the conventional DC to DC boost converter. Most important benefit of this interleaved DC to DC boost converter is much higher efficiency. The input current is divided into two paths, substantially ohmic loss (I2R) and inductor ac loss gets reduced and finally the system achieves much higher efficiency. With recent mandates on energy saving interleaved DC to DC boost converter may be used as a very powerful tool to maintain good power density keeping the input current manageable. Higher efficiency also allows higher switching frequency and as a result the topology becomes more compact and cost friendly. The proposed topology boosts 48v DC to 200 V DC. Switching frequency is 100 kHz and PSIM 9.1 Platform has been used for the simulation.

AC to DC Bridgeless Boost Converter for Ultra Low Input Energy Harvesting

NASA Astrophysics Data System (ADS)

Dawam, A. H. A.; Muhamad, M.

2018-03-01

This paper presents design of circuit which converts low input AC voltage to a higher output DC voltage. A buck-boost topology and boost topology are combined to condition cycle of an AC input voltage. the unique integration of a combining circuit of buck-boost and boost circuit have been proposed in order to introduce a new direct ac-dc power converter topology without conventional diode bridge rectifier. The converter achieved to convert a milli-volt scale of input AC voltage into a volt scale of output DC voltages which is from 400mV to 3.3V.

Optimal design of a vibration-based energy harvester using magnetostrictive material (MsM)

NASA Astrophysics Data System (ADS)

Hu, J.; Xu, F.; Huang, A. Q.; Yuan, F. G.

2011-01-01

In this study, an optimal vibration-based energy harvesting system using magnetostrictive material (MsM) was designed and tested to enable the powering of a wireless sensor. In particular, the conversion efficiency, converting from magnetic to electric energy, is approximately modeled from the magnetic field induced by the beam vibration. A number of factors that affect the output power such as the number of MsM layers, coil design and load matching are analyzed and explored in the design optimization. From the measurements, the open-circuit voltage can reach 1.5 V when the MsM cantilever beam operates at the second natural frequency 324 Hz. The AC output power is 970 µW, giving a power density of 279 µW cm - 3. The attempt to use electrical reactive components (either inductors or capacitors) to resonate the system at any frequency has also been analyzed and tested experimentally. The results showed that this approach is not feasible to optimize the power. Since the MsM device has low output voltage characteristics, a full-wave quadrupler has been designed to boost the rectified output voltage. To deliver the maximum output power to the load, a complex conjugate impedance matching between the load and the MsM device is implemented using a discontinuous conduction mode (DCM) buck-boost converter. The DC output power after the voltage quadrupler reaches 705 µW and the corresponding power density is 202 µW cm - 3. The output power delivered to a lithium rechargeable battery is around 630 µW, independent of the load resistance.

Impact of power index, hydroureteronephrosis, stone size, and composition on the efficacy of in situ boosted ESWL for primary proximal ureteral calculi.

PubMed

Singh, I; Gupta, N P; Hemal, A K; Dogra, P N; Ansari, M S; Seth, A; Aron, M

2001-07-01

The efficacy, safety, feasibility, and outcome of in situ treatment applied to select proximal ureteral calculi was assessed and analyzed with a view to avoiding auxiliary interventions and providing high clearance rates in the shortest possible time. We studied the impact of several clinically important variables, including power index, degree of hydroureteronephrosis (HDUN), stone size, and composition on the efficacy of sequential in situ boosted extracorporeal shock wave lithotripsy (ESWL) in a select group. The power index requirement for the in situ boosted protocol and the impact of the stone size/composition, degree of HDUN, and clearance rates were also analyzed. An in situ (no instrumentation) boosted protocol was applied to 130 primary unimpacted proximal ureteral calculi with no prior intervention. A typical session with the Siemens Lithostar Plus comprised 3000 shock waves, in installments of 500, deployed at a power setting of 1 to 4 kV with a gradual stepwise escalation. Sequential boosted additional sessions of ESWL were administered on days 2, 7, and 14, tailored to the degree of fragmentation, clearance status, and amount of residual stone bulk. Several parameters (shock waves, kilovolts used, fluoroscopy time, number of sessions, stone size, composition, fragmentation, clearance, and HDUN) were recorded and the results analyzed statistically. The results were excellent in 83.8%, with a mean duration to complete clearance of 11.3 days. In situ ESWL failed in 7.69%, and the auxiliary intervention rate was 10.7%. Pre-ESWL HDUN was present in 78.3%, the mean power index was 184.6/session/case, and the average stone burden was 8.9 mm(2). Calcium oxalate monohydrate was the most common stone (56%). Renal colic was the most common side effect observed. The power index, fragmentation at the first session, and stone size were found to be the most favorable significant variables affecting stone clearance. The degree of HDUN, number of sessions, and stone composition did not significantly impact the clearance rates. In situ boosted ESWL should be the first-line therapeutic modality in select unimpacted primary proximal ureteral stones.

Designing of new structure PID controller of boost converter for solar photovoltaic stability

NASA Astrophysics Data System (ADS)

Shabrina, Hanifati Nur; Setiawan, Eko Adhi; Sabirin, Chip Rinaldi

2017-03-01

Nowadays, the utilization of renewable energy as the source on distributed generation system is increasing. It aims to reduce reliance and power losses from utility grid and improve power stability in near loads. One example of renewable energy technology that have been highly proven on the market is solar photovoltaic (PV). This technology converts photon from sunlight into electricity. However, the fluctuation of solar radiation that often occurs become the main problem for this system. Due to this condition, the power conversion is needed to convert the change frequently in photovoltaic panel into a stable voltage to the system. Developing control of boost converter has important role to keep ability of system stabilization. A conventional PID (Proportional, Integral, Derivative) control is mostly used to achieve this goal. In this research, a design of new structure PID controller of boost converter is offered to better optimize system stability comparing to the conventional PID. Parameters obtained from this PID structure have been successfully yield a stable boost converter output at 200 V with 10% overshoot, 1.5 seconds of settling time, and 1.5% of steady-state error.

Input-current shaped ac to dc converters

NASA Technical Reports Server (NTRS)

1986-01-01

The problem of achieving near unity power factor while supplying power to a dc load from a single phase ac source of power is examined. Power processors for this application must perform three functions: input current shaping, energy storage, and output voltage regulation. The methods available for performing each of these three functions are reviewed. Input current shaping methods are either active or passive, with the active methods divided into buck-like and boost-like techniques. In addition to large reactances, energy storage methods include resonant filters, active filters, and active storage schemes. Fast voltage regulation can be achieved by post regulation or by supplementing the current shaping topology with an extra switch. Some indications of which methods are best suited for particular applications concludes the discussion.

Experimental Research in Boost Driver with EDLCs

NASA Astrophysics Data System (ADS)

Matsumoto, Hirokazu

The supply used in servo systems tends to have a high voltage in order to reduce loss and improve the response of motor drives. We propose a new boost motor driver that comprises EDLCs. The proposed driver has a simple structure, wherein the EDLCs are connected in series to the supply, and comprises a charge circuit to charge the EDLCs. The proposed driver has three advantages over conventional boost drivers. The first advantage is that the driver can easily attain the stable boost voltage. The second advantage is that the driver can reduce input power peaks. In a servo system, the input power peaks become greater than the rated power in order to accelerate the motor rapidly. This implies that the equipments that supply power to servo systems must have sufficient power capacity to satisfy the power peaks. The proposed driver can suppress the increase of the power capacity of supply facilities. The third advantage is that the driver can store almost all of the regenerative energy. Conventional drivers have a braking resistor to suppress the increase in the DC link voltage. This causes a considerable reduction in the efficiency. The proposed driver is more efficient than conventional drivers. In this study, the experimental results confirmed the effectiveness of the proposed driver and showed that the drive performance of the proposed driver is the same as that of a conventional driver. Furthermore, it was confirmed that the results of the simulation of a model of the EDLC module, whose capacitance is dependent on the frequency, correspond well with the experimental results.

A Modular PMAD System for Small Spacecraft

NASA Technical Reports Server (NTRS)

Button, Robert M.

1998-01-01

Current trends in satellite design are focused on developing small, reliable, and inexpensive spacecraft. To that end, a modular power management and distribution system (PMAD) is proposed which will help transition the aerospace industry towards an assembly line approach to building spacecraft. The modular system is based on an innovative DC voltage boost converter called the Series Connected Boost Regulator (SCBR). The SCBR uses existing DC-DC converters and adds a unique series connection. This simple modification provides the SCBR topology with many advantages over existing boost converters. Efficiencies of 94-98%, power densities above 1,000 We/kg, and inherent fault tolerance are just a few of the characteristics presented. Limitations of the SCBR technology are presented, and it is shown that the SCBR makes an ideal photovoltaic array regulator. A modular design based on the series connected boost unit is outlined and functional descriptions of the components are given.

Mathematical simulation of power conditioning systems. Volume 1: Simulation of elementary units. Report on simulation methodology

NASA Technical Reports Server (NTRS)

Prajous, R.; Mazankine, J.; Ippolito, J. C.

1978-01-01

Methods and algorithms used for the simulation of elementary power conditioning units buck, boost, and buck-boost, as well as shunt PWM are described. Definitions are given of similar converters and reduced parameters. The various parts of the simulation to be carried out are dealt with; local stability, corrective network, measurements of input-output impedance and global stability. A simulation example is given.

ASDTIC control and standardized interface circuits applied to buck, parallel and buck-boost dc to dc power converters

NASA Technical Reports Server (NTRS)

Schoenfeld, A. D.; Yu, Y.

1973-01-01

Versatile standardized pulse modulation nondissipatively regulated control signal processing circuits were applied to three most commonly used dc to dc power converter configurations: (1) the series switching buck-regulator, (2) the pulse modulated parallel inverter, and (3) the buck-boost converter. The unique control concept and the commonality of control functions for all switching regulators have resulted in improved static and dynamic performance and control circuit standardization. New power-circuit technology was also applied to enhance reliability and to achieve optimum weight and efficiency.

A 1.1nW Energy Harvesting System with 544pW Quiescent Power for Next Generation Implants

PubMed Central

Mercier, Patrick P.; Lysaght, Andrew C.; Stankovic, Konstantina M.; Chandrakasan, Anantha P.

2015-01-01

This paper presents a nW power management unit (PMU) for an autonomous wireless sensor that sustains itself by harvesting energy from the endocochlear potential (EP), the 70–100 mV electrochemical bio-potential inside the mammalian ear. Due to the anatomical constraints inside the inner ear, the total extractable power from the EP is limited to 1.1–6.25 nW. A nW boost converter is used to increase the input voltage (30–55 mV) to a higher voltage (0.8 to 1.1 V) usable by CMOS circuits in the sensor. A pW Charge Pump circuit is used to minimize the leakage in the boost converter. Further, ultra-low-power control circuits consisting of digital implementations of input impedance adjustment circuits and Zero Current Switching circuits along with Timer and Reference circuits keep the quiescent power of the PMU down to 544 pW. The designed boost converter achieves a peak power conversion efficiency of 56%. The PMU can sustain itself and a duty-cyled ultra-low power load while extracting power from the EP of a live guinea pig. The PMU circuits have been implemented on a 0.18µm CMOS process. PMID:25983340

A 1.1nW Energy Harvesting System with 544pW Quiescent Power for Next Generation Implants.

PubMed

Bandyopadhyay, Saurav; Mercier, Patrick P; Lysaght, Andrew C; Stankovic, Konstantina M; Chandrakasan, Anantha P

2014-12-01

This paper presents a nW power management unit (PMU) for an autonomous wireless sensor that sustains itself by harvesting energy from the endocochlear potential (EP), the 70-100 mV electrochemical bio-potential inside the mammalian ear. Due to the anatomical constraints inside the inner ear, the total extractable power from the EP is limited to 1.1-6.25 nW. A nW boost converter is used to increase the input voltage (30-55 mV) to a higher voltage (0.8 to 1.1 V) usable by CMOS circuits in the sensor. A pW Charge Pump circuit is used to minimize the leakage in the boost converter. Further, ultra-low-power control circuits consisting of digital implementations of input impedance adjustment circuits and Zero Current Switching circuits along with Timer and Reference circuits keep the quiescent power of the PMU down to 544 pW. The designed boost converter achieves a peak power conversion efficiency of 56%. The PMU can sustain itself and a duty-cyled ultra-low power load while extracting power from the EP of a live guinea pig. The PMU circuits have been implemented on a 0.18µm CMOS process.

Quality engineering tools focused on high power LED driver design using boost power stages in switch mode

NASA Astrophysics Data System (ADS)

Ileana, Ioan; Risteiu, Mircea; Marc, Gheorghe

2016-12-01

This paper is a part of our research dedicated to high power LED lamps designing. The boost-up selected technology wants to meet driver producers' tendency in the frame of efficiency and disturbances constrains. In our work we used modeling and simulation tools for implementing scenarios of the driver work when some controlling functions are executed (output voltage/ current versus input voltage and fixed switching frequency, input and output electric power transfer versus switching frequency, transient inductor voltage analysis, and transient out capacitor analysis). Some electrical and thermal stress conditions are also analyzed. Based on these aspects, a high reliable power LED driver has been designed.

Can we predict Acute Medical readmissions using the BOOST tool? A retrospective case note review.

PubMed

Lee, Geraldine A; Freedman, Daniel; Beddoes, Penelope; Lyness, Emily; Nixon, Imogen; Srivastava, Vivek

2016-01-01

Readmissions within 30-days of hospital discharge are a problem. The aim was to determine if the Better Outcomes for Older Adults through Safe Transitions (BOOST) risk assessment tool was applicable within the UK. Patients over 65 readmitted were identified retrospectively via a casenote review. BOOST assessment was applied with 1 point for each risk factor. 324 patients were readmitted (mean age 77 years) with a median of 7 days between discharge and readmission. The median BOOST score was 3 (IQR 2-4) with polypharmacy evident in 88% and prior hospitalisation in 70%. The tool correctly predicted 90% of readmissions using two or more risk factors and 99.1% if one risk factor was included. The BOOST assessment tool appears appropriate in predicting readmissions however further analysis is required to determine its precision.

Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies

PubMed Central

Manitz, Juliane; Burger, Patricia; Amos, Christopher I.; Chang-Claude, Jenny; Wichmann, Heinz-Erich; Kneib, Thomas; Bickeböller, Heike

2017-01-01

The analysis of genome-wide association studies (GWAS) benefits from the investigation of biologically meaningful gene sets, such as gene-interaction networks (pathways). We propose an extension to a successful kernel-based pathway analysis approach by integrating kernel functions into a powerful algorithmic framework for variable selection, to enable investigation of multiple pathways simultaneously. We employ genetic similarity kernels from the logistic kernel machine test (LKMT) as base-learners in a boosting algorithm. A model to explain case-control status is created iteratively by selecting pathways that improve its prediction ability. We evaluated our method in simulation studies adopting 50 pathways for different sample sizes and genetic effect strengths. Additionally, we included an exemplary application of kernel boosting to a rheumatoid arthritis and a lung cancer dataset. Simulations indicate that kernel boosting outperforms the LKMT in certain genetic scenarios. Applications to GWAS data on rheumatoid arthritis and lung cancer resulted in sparse models which were based on pathways interpretable in a clinical sense. Kernel boosting is highly flexible in terms of considered variables and overcomes the problem of multiple testing. Additionally, it enables the prediction of clinical outcomes. Thus, kernel boosting constitutes a new, powerful tool in the analysis of GWAS data and towards the understanding of biological processes involved in disease susceptibility. PMID:28785300

Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies.

PubMed

Friedrichs, Stefanie; Manitz, Juliane; Burger, Patricia; Amos, Christopher I; Risch, Angela; Chang-Claude, Jenny; Wichmann, Heinz-Erich; Kneib, Thomas; Bickeböller, Heike; Hofner, Benjamin

2017-01-01

The analysis of genome-wide association studies (GWAS) benefits from the investigation of biologically meaningful gene sets, such as gene-interaction networks (pathways). We propose an extension to a successful kernel-based pathway analysis approach by integrating kernel functions into a powerful algorithmic framework for variable selection, to enable investigation of multiple pathways simultaneously. We employ genetic similarity kernels from the logistic kernel machine test (LKMT) as base-learners in a boosting algorithm. A model to explain case-control status is created iteratively by selecting pathways that improve its prediction ability. We evaluated our method in simulation studies adopting 50 pathways for different sample sizes and genetic effect strengths. Additionally, we included an exemplary application of kernel boosting to a rheumatoid arthritis and a lung cancer dataset. Simulations indicate that kernel boosting outperforms the LKMT in certain genetic scenarios. Applications to GWAS data on rheumatoid arthritis and lung cancer resulted in sparse models which were based on pathways interpretable in a clinical sense. Kernel boosting is highly flexible in terms of considered variables and overcomes the problem of multiple testing. Additionally, it enables the prediction of clinical outcomes. Thus, kernel boosting constitutes a new, powerful tool in the analysis of GWAS data and towards the understanding of biological processes involved in disease susceptibility.

Solar pv fed stand-alone excitation system of a synchronous machine for reactive power generation

NASA Astrophysics Data System (ADS)

Sudhakar, N.; Jain, Siddhartha; Jyotheeswara Reddy, K.

2017-11-01

This paper presents a model of a stand-alone solar energy conversion system based on synchronous machine working as a synchronous condenser in overexcited state. The proposed model consists of a Synchronous Condenser, a DC/DC boost converter whose output is fed to the field of the SC. The boost converter is supplied by the modelled solar panel and a day time variable irradiance is fed to the panel during the simulation time. The model also has one alternate source of rechargeable batteries for the time when irradiance falls below a threshold value. Also the excess power produced when there is ample irradiance is divided in two parts and one is fed to the boost converter while other is utilized to recharge the batteries. A simulation is done in MATLAB-SIMULINK and the obtained results show the utility of such modelling for supplying reactive power is feasible.

A Bidirectional High-Power-Quality Grid Interface With a Novel Bidirectional Noninverted Buck Boost Converter for PHEVs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Onar, Omer C

2012-01-01

Plug-in hybrid electric vehicles (PHEVs) will play a vital role in future sustainable transportation systems due to their potential in terms of energy security, decreased environmental impact, improved fuel economy, and better performance. Moreover, new regulations have been established to improve the collective gas mileage, cut greenhouse gas emissions, and reduce dependence on foreign oil. This paper primarily focuses on two major thrust areas of PHEVs. First, it introduces a grid-friendly bidirectional alternating current/direct current ac/dc dc/ac rectifier/inverter for facilitating vehicle-to-grid (V2G) integration of PHEVs. Second, it presents an integrated bidirectional noninverted buck boost converter that interfaces the energy storagemore » device of the PHEV to the dc link in both grid-connected and driving modes. The proposed bidirectional converter has minimal grid-level disruptions in terms of power factor and total harmonic distortion, with less switching noise. The integrated bidirectional dc/dc converter assists the grid interface converter to track the charge/discharge power of the PHEV battery. In addition, while driving, the dc/dc converter provides a regulated dc link voltage to the motor drive and captures the braking energy during regenerative braking.« less

Physics of a ballistic missile defense - The chemical laser boost-phase defense

NASA Technical Reports Server (NTRS)

Grabbe, Crockett L.

1988-01-01

The basic physics involved in proposals to use a chemical laser based on satellites for a boost-phase defense are investigated. After a brief consideration of simple physical conditions for the defense, a calculation of an equation for the number of satellites needed for the defense is made along with some typical values of this for possible future conditions for the defense. Basic energy and power requirements for the defense are determined. A sumary is made of probable minimum conditions that must be achieved for laser power, targeting accuracy, number of satellites, and total sources for power needed.

Operation strategy for grid-tied DC-coupling power converter interface integrating wind/solar/battery

NASA Astrophysics Data System (ADS)

Jou, H. L.; Wu, J. C.; Lin, J. H.; Su, W. N.; Wu, T. S.; Lin, Y. T.

2017-11-01

The operation strategy for a small-capacity grid-tied DC-coupling power converter interface (GDPCI) integrating wind energy, solar energy and battery energy storage is proposed. The GDPCI is composed of a wind generator, a solar module set a battery bank, a boost DC-DC power converter (DDPC), a bidirectional DDPC power converter, an AC-DC power converter (ADPC) and a five-level DC-AC inverter (DAI). A solar module set, a wind generator and a battery bank are coupled to the common DC bus through the boost DDPC, the ADPC and the bidirectional DDPC, respectively. For verifying the performance of the GDPCI under different operation modes, computer simulation is carried out by PSIM.

OAO-3 end of mission power subsystem evaluation

NASA Technical Reports Server (NTRS)

Tasevoli, M.

1982-01-01

End of mission tests were performed on the OAO-3 power subsystem in three component areas: solar array, nickel-cadmium batteries and the On-Board Processor (OBP) power boost operation. Solar array evaluation consisted of analyzing array performance characteristics and comparing them to earlier flight data. Measured solar array degradation of 14.1 to 17.7% after 8 1/3 years is in good agreement with theortical radiation damage losses. Battery discharge characteristics were compared to results of laboratory life cycle tests performed on similar cells. Comparison of cell voltage profils reveals close correlation and confirms the validity of real time life cycle simulation. The successful operation of the system in the OBP/power boost regulation mode demonstrates the excellent life, reliability and greater system utilization of power subsystems using maximum power trackers.

Fuzzy Logic Controlled Solar Module for Driving Three- Phase Induction Motor

NASA Astrophysics Data System (ADS)

Afiqah Zainal, Nurul; Sooi Tat, Chan; Ajisman

2016-02-01

Renewable energy produced by solar module gives advantages for generated three- phase induction motor in remote area. But, solar module's ou tput is uncertain and complex. Fuzzy logic controller is one of controllers that can handle non-linear system and maximum power of solar module. Fuzzy logic controller used for Maximum Power Point Tracking (MPPT) technique to control Pulse-Width Modulation (PWM) for switching power electronics circuit. DC-DC boost converter used to boost up photovoltaic voltage to desired output and supply voltage source inverter which controlled by three-phase PWM generated by microcontroller. IGBT switched Voltage source inverter (VSI) produced alternating current (AC) voltage from direct current (DC) source to control speed of three-phase induction motor from boost converter output. Results showed that, the output power of solar module is optimized and controlled by using fuzzy logic controller. Besides that, the three-phase induction motor can be drive and control using VSI switching by the PWM signal generated by the fuzzy logic controller. This concluded that the non-linear system can be controlled and used in driving three-phase induction motor.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Larkoski, Andrew J.; Moult, Ian; Neill, Duff

Observables which discriminate boosted topologies from massive QCD jets are of great importance for the success of the jet substructure program at the Large Hadron Collider. Such observables, while both widely and successfully used, have been studied almost exclusively with Monte Carlo simulations. In this paper we present the first all-orders factorization theorem for a two-prong discriminant based on a jet shape variable, D 2, valid for both signal and background jets. Our factorization theorem simultaneously describes the production of both collinear and soft subjets, and we introduce a novel zero-bin procedure to correctly describe the transition region between thesemore » limits. By proving an all orders factorization theorem, we enable a systematically improvable description, and allow for precision comparisons between data, Monte Carlo, and first principles QCD calculations for jet substructure observables. Using our factorization theorem, we present numerical results for the discrimination of a boosted Z boson from massive QCD background jets. We compare our results with Monte Carlo predictions which allows for a detailed understanding of the extent to which these generators accurately describe the formation of two-prong QCD jets, and informs their usage in substructure analyses. In conclusion, our calculation also provides considerable insight into the discrimination power and calculability of jet substructure observables in general.« less

State-plane analysis of zero-voltage-switching resonant dc/dc power converters

NASA Astrophysics Data System (ADS)

Kazimierczuk, Marian K.; Morse, William D.

The state-plane analysis technique for the zero-voltage-switching resonant dc/dc power converter family of topologies, namely the buck, boost, buck-boost, and Cuk converters is established. The state plane provides a compression of information that allows the designer to uniquely examine the nonlinear dynamics of resonant converter operation. Utilizing the state plane, resonant converter modes of operation are examined and the switching frequencies are derived for the boundaries between these modes, including the boundary of energy conversion.

Modeling of switching regulator power stages with and without zero-inductor-current dwell time

NASA Technical Reports Server (NTRS)

Lee, F. C.; Yu, Y.; Triner, J. E.

1976-01-01

State space techniques are employed to derive accurate models for buck, boost, and buck/boost converter power stages operating with and without zero-inductor-current dwell time. A generalized procedure is developed which treats the continuous-inductor-current mode without the dwell time as a special case of the discontinuous-current mode, when the dwell time vanishes. An abrupt change of system behavior including a reduction of the system order when the dwell time appears is shown both analytically and experimentally.

Methods, systems and apparatus for controlling operation of two alternating current (AC) machines

DOEpatents

Gallegos-Lopez, Gabriel [Torrance, CA; Nagashima, James M [Cerritos, CA; Perisic, Milun [Torrance, CA; Hiti, Silva [Redondo Beach, CA

2012-02-14

A system is provided for controlling two AC machines. The system comprises a DC input voltage source that provides a DC input voltage, a voltage boost command control module (VBCCM), a five-phase PWM inverter module coupled to the two AC machines, and a boost converter coupled to the inverter module and the DC input voltage source. The boost converter is designed to supply a new DC input voltage to the inverter module having a value that is greater than or equal to a value of the DC input voltage. The VBCCM generates a boost command signal (BCS) based on modulation indexes from the two AC machines. The BCS controls the boost converter such that the boost converter generates the new DC input voltage in response to the BCS. When the two AC machines require additional voltage that exceeds the DC input voltage required to meet a combined target mechanical power required by the two AC machines, the BCS controls the boost converter to drive the new DC input voltage generated by the boost converter to a value greater than the DC input voltage.

Constructing Nucleon Operators on a Lattice for Form Factors with High Momentum Transfer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Syritsyn, Sergey; Gambhir, Arjun S.; Musch, Bernhard U.

We present preliminary results of computing nucleon form factor at high momentum transfer using the 'boosted' or 'momentum' smearing. We use gauge configurations generated with N f = 2 + 1dynamical Wilson-clover fermions and study the connected as well as disconnected contributions to the nucleon form factors. Our initial results indicate that boosted smearing helps to improve the signal for nucleon correlators at high momentum. However, we also find evidence for large excited state contributions, which will likely require variational analysis to isolate the boosted nucleon ground state.

Modeling a constant power load for nickel-hydrogen battery testing using SPICE

NASA Technical Reports Server (NTRS)

Bearden, Douglas B.; Lollar, Louis F.; Nelms, R. M.

1990-01-01

The effort to design and model a constant power load for the HST (Hubble Space Telescope) nickel-hydrogen battery tests is described. The constant power load was designed for three different simulations on the batteries: life cycling, reconditioning, and capacity testing. A dc-dc boost converter was designed to act as this constant power load. A boost converter design was chosen because of the low test battery voltage (4 to 6 VDC) generated and the relatively high power requirement of 60 to 70 W. The SPICE model was shown to consistently predict variations in the actual circuit as various designs were attempted. It is concluded that the confidence established in the SPICE model of the constant power load ensures its extensive utilization in future efforts to improve performance in the actual load circuit.

A nonlinear control scheme based on dynamic evolution path theory for improved dynamic performance of boost PFC converter working on nonlinear features.

PubMed

Mohanty, Pratap Ranjan; Panda, Anup Kumar

2016-11-01

This paper is concerned to performance improvement of boost PFC converter under large random load fluctuation, ensuring unity power factor (UPF) at source end and regulated voltage at load side. To obtain such performance, a nonlinear controller based on dynamic evolution path theory is designed and its robustness is examined under both heavy and light loading condition. In this paper, %THD and zero-cross-over dead-zone of input current is significantly reduced. Also, very less response time of input current and output voltage to that of load and reference variation is remarked. A simulation model of proposed system is designed and it is realized using dSPACE 1104 signal processor for a 390V DC , 500W prototype. The relevant experimental and simulation waveforms are presented. Copyright © 2016 ISA. Published by Elsevier Ltd. All rights reserved.

Chaos control in solar fed DC-DC boost converter by optimal parameters using nelder-mead algorithm powered enhanced BFOA

NASA Astrophysics Data System (ADS)

Sudhakar, N.; Rajasekar, N.; Akhil, Saya; Jyotheeswara Reddy, K.

2017-11-01

The boost converter is the most desirable DC-DC power converter for renewable energy applications for its favorable continuous input current characteristics. In other hand, these DC-DC converters known as practical nonlinear systems are prone to several types of nonlinear phenomena including bifurcation, quasiperiodicity, intermittency and chaos. These undesirable effects has to be controlled for maintaining normal periodic operation of the converter and to ensure the stability. This paper presents an effective solution to control the chaos in solar fed DC-DC boost converter since the converter experiences wide range of input power variation which leads to chaotic phenomena. Controlling of chaos is significantly achieved using optimal circuit parameters obtained through Nelder-Mead Enhanced Bacterial Foraging Optimization Algorithm. The optimization renders the suitable parameters in minimum computational time. The results are compared with the traditional methods. The obtained results of the proposed system ensures the operation of the converter within the controllable region.

Solar power generation system for reducing leakage current

NASA Astrophysics Data System (ADS)

Wu, Jinn-Chang; Jou, Hurng-Liahng; Hung, Chih-Yi

2018-04-01

This paper proposes a transformer-less multi-level solar power generation system. This solar power generation system is composed of a solar cell array, a boost power converter, an isolation switch set and a full-bridge inverter. A unipolar pulse-width modulation (PWM) strategy is used in the full-bridge inverter to attenuate the output ripple current. Circuit isolation is accomplished by integrating the isolation switch set between the solar cell array and the utility, to suppress the leakage current. The isolation switch set also determines the DC bus voltage for the full-bridge inverter connecting to the solar cell array or the output of the boost power converter. Accordingly, the proposed transformer-less multi-level solar power generation system generates a five-level voltage, and the partial power of the solar cell array is also converted to AC power using only the full-bridge inverter, so the power efficiency is increased. A prototype is developed to validate the performance of the proposed transformer-less multi-level solar power generation system.

Boosting BCG-primed responses with a subunit Apa vaccine during the waning phase improves immunity and imparts protection against Mycobacterium tuberculosis.

PubMed

Nandakumar, Subhadra; Kannanganat, Sunil; Dobos, Karen M; Lucas, Megan; Spencer, John S; Amara, Rama Rao; Plikaytis, Bonnie B; Posey, James E; Sable, Suraj B

2016-05-13

Heterologous prime-boosting has emerged as a powerful vaccination approach against tuberculosis. However, optimal timing to boost BCG-immunity using subunit vaccines remains unclear in clinical trials. Here, we followed the adhesin Apa-specific T-cell responses in BCG-primed mice and investigated its BCG-booster potential. The Apa-specific T-cell response peaked 32-52 weeks after parenteral or mucosal BCG-priming but waned significantly by 78 weeks. A subunit-Apa-boost during the contraction-phase of BCG-response had a greater effect on the magnitude and functional quality of specific cellular and humoral responses compared to a boost at the peak of BCG-response. The cellular response increased following mucosal BCG-prime-Apa-subunit-boost strategy compared to Apa-subunit-prime-BCG-boost approach. However, parenteral BCG-prime-Apa-subunit-boost by a homologous route was the most effective strategy in-terms of enhancing specific T-cell responses during waning in the lung and spleen. Two Apa-boosters markedly improved waning BCG-immunity and significantly reduced Mycobacterium tuberculosis burdens post-challenge. Our results highlight the challenges of optimization of prime-boost regimens in mice where BCG drives persistent immune-activation and suggest that boosting with a heterologous vaccine may be ideal once the specific persisting effector responses are contracted. Our results have important implications for design of prime-boost regimens against tuberculosis in humans.

Performance evaluation of a high power DC-DC boost converter for PV applications using SiC power devices

NASA Astrophysics Data System (ADS)

Almasoudi, Fahad M.; Alatawi, Khaled S.; Matin, Mohammad

2016-09-01

The development of Wide band gap (WBG) power devices has been attracted by many commercial companies to be available in the market because of their enormous advantages over the traditional Si power devices. An example of WBG material is SiC, which offers a number of advantages over Si material. For example, SiC has the ability of blocking higher voltages, reducing switching and conduction losses and supports high switching frequency. Consequently, SiC power devices have become the affordable choice for high frequency and power application. The goal of this paper is to study the performance of 4.5 kW, 200 kHz, 600V DC-DC boost converter operating in continuous conduction mode (CCM) for PV applications. The switching behavior and turn on and turn off losses of different switching power devices such as SiC MOSFET, SiC normally ON JFET and Si MOSFET are investigated and analyzed. Moreover, a detailed comparison is provided to show the overall efficiency of the DC-DC boost converter with different switching power devices. It is found that the efficiency of SiC power switching devices are higher than the efficiency of Si-based switching devices due to low switching and conduction losses when operating at high frequencies. According to the result, the performance of SiC switching power devices dominate the conventional Si power devices in terms of low losses, high efficiency and high power density. Accordingly, SiC power switching devices are more appropriate for PV applications where a converter of smaller size with high efficiency, and cost effective is required.

Characterizing boosted dijet resonances with energy correlation functions

NASA Astrophysics Data System (ADS)

Chivukula, R. Sekhar; Mohan, Kirtimaan A.; Sengupta, Dipan; Simmons, Elizabeth H.

2018-03-01

Jet Energy Correlation Variables are powerful tools to study jet physics at LHC. We show that a class of such variables, known as Energy Correlation Functions can be used effectively to discover and distinguish a wide variety of boosted light dijet resonances at the LHC through sensitivity to their transverse momentum and color structures.

An Update on Statistical Boosting in Biomedicine.

PubMed

Mayr, Andreas; Hofner, Benjamin; Waldmann, Elisabeth; Hepp, Tobias; Meyer, Sebastian; Gefeller, Olaf

2017-01-01

Statistical boosting algorithms have triggered a lot of research during the last decade. They combine a powerful machine learning approach with classical statistical modelling, offering various practical advantages like automated variable selection and implicit regularization of effect estimates. They are extremely flexible, as the underlying base-learners (regression functions defining the type of effect for the explanatory variables) can be combined with any kind of loss function (target function to be optimized, defining the type of regression setting). In this review article, we highlight the most recent methodological developments on statistical boosting regarding variable selection, functional regression, and advanced time-to-event modelling. Additionally, we provide a short overview on relevant applications of statistical boosting in biomedicine.

Boosting BCG-primed responses with a subunit Apa vaccine during the waning phase improves immunity and imparts protection against Mycobacterium tuberculosis

PubMed Central

Nandakumar, Subhadra; Kannanganat, Sunil; Dobos, Karen M.; Lucas, Megan; Spencer, John S.; Amara, Rama Rao; Plikaytis, Bonnie B.; Posey, James E.; Sable, Suraj B.

2016-01-01

Heterologous prime–boosting has emerged as a powerful vaccination approach against tuberculosis. However, optimal timing to boost BCG-immunity using subunit vaccines remains unclear in clinical trials. Here, we followed the adhesin Apa-specific T-cell responses in BCG-primed mice and investigated its BCG-booster potential. The Apa-specific T-cell response peaked 32–52 weeks after parenteral or mucosal BCG-priming but waned significantly by 78 weeks. A subunit-Apa-boost during the contraction-phase of BCG-response had a greater effect on the magnitude and functional quality of specific cellular and humoral responses compared to a boost at the peak of BCG-response. The cellular response increased following mucosal BCG-prime–Apa-subunit-boost strategy compared to Apa-subunit-prime–BCG-boost approach. However, parenteral BCG-prime–Apa-subunit-boost by a homologous route was the most effective strategy in-terms of enhancing specific T-cell responses during waning in the lung and spleen. Two Apa-boosters markedly improved waning BCG-immunity and significantly reduced Mycobacterium tuberculosis burdens post-challenge. Our results highlight the challenges of optimization of prime–boost regimens in mice where BCG drives persistent immune-activation and suggest that boosting with a heterologous vaccine may be ideal once the specific persisting effector responses are contracted. Our results have important implications for design of prime–boost regimens against tuberculosis in humans. PMID:27173443

16,000-rpm Interior Permanent Magnet Reluctance Machine with Brushless Field Excitation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hsu, J.S.; Burress, T.A.; Lee, S.T.

2007-10-31

The reluctance interior permanent magnet (RIPM) motor is currently used by many leading auto manufacturers for hybrid vehicles. The power density for this type of motor is high compared with that of induction motors and switched reluctance motors. The primary drawback of the RIPM motor is the permanent magnet (PM) because during high-speed operation, the fixed PM produces a huge back electromotive force (emf) that must be reduced before the current will pass through the stator windings. This reduction in back-emf is accomplished with a significant direct-axis (d-axis) demagnetization current, which opposes the PM's flux to reduce the flux seenmore » by the stator wires. This may lower the power factor and efficiency of the motor and raise the requirement on the alternate current (ac) power supply; consequently, bigger inverter switching components, thicker motor winding conductors, and heavier cables are required. The direct current (dc) link capacitor is also affected when it must accommodate heavier harmonic currents. It is commonly agreed that, for synchronous machines, the power factor can be optimized by varying the field excitation to minimize the current. The field produced by the PM is fixed and cannot be adjusted. What can be adjusted is reactive current to the d-axis of the stator winding, which consumes reactive power but does not always help to improve the power factor. The objective of this project is to avoid the primary drawbacks of the RIPM motor by introducing brushless field excitation (BFE). This offers both high torque per ampere (A) per core length at low speed by using flux, which is enhanced by increasing current to a fixed excitation coil, and flux, which is weakened at high speed by reducing current to the excitation coil. If field weakening is used, the dc/dc boost converter used in a conventional RIPM motor may be eliminated to reduce system costs. However, BFE supports a drive system with a dc/dc boost converter, because it can further extend the constant power speed range of the drive system and adjust the field for power factor and efficiency gains. Lower core losses at low torque regions, especially at high speeds, are attained by reducing the field excitation. Safety and reliability are increased by weakening the field when a winding short-circuit fault occurs, preventing damage to the motor. For a high-speed motor operating at 16,000-revolutions per minute (rpm), mechanical stress is a challenge. Bridges that link the rotor punching segments together must be thickened for mechanical integrity; consequently, increased rotor flux leakage significantly lowers motor performance. This barrier can be overcome by BFE to ensure sufficient rotor flux when needed.« less

The Albedo of Kepler's Small Worlds

NASA Astrophysics Data System (ADS)

Jansen, Tiffany; Kipping, David

2018-01-01

The study of exoplanet phase curves has been established as a powerful tool for measuring the atmospheric properties of other worlds. To first order, phase curves have the same amplitude as occultations, yet far greater temporal baselines enabling substantial improvements in sensitivity. Even so, only a relatively small fraction of Kepler planets have detectable phase curves, leading to a population dominated by hot-Jupiters. One way to boost sensitivity further is to stack different planets of similar types together, giving rise to an average phase curve for a specific ensemble. In this work, we measure the average albedo, thermal redistribution efficiency, and greenhouse boosting factor from the average phase curves of 115 Neptunian and 50 Terran (solid) worlds. We construct ensemble phase curve models for both samples accounting for the reflection and thermal components and regress our models assuming a global albedo, redistribution factor and greenhouse factor in a Bayesian framework. We find modest evidence for a detected phase curve in the Neptunian sample, although the albedo and thermal properties are somewhat degenerate meaning we can only place an upper limit on the albedo of Ag < 0.23 and greenhouse factor of f < 1.40 to 95% confidence. As predicted theoretically, this confirms hot-Neptunes are darker than Neptune and Uranus. Additionally, we place a constraint on the albedo of solid, Terran worlds of Ag < 0.42 and f < 1.60 to 95% confidence, compatible with a dark Lunar-like surface.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moureau-Zabotto, Laurence, E-mail: moureaul@ipc.unicancer.fr; Ortholan, Cecile; Hannoun-Levi, Jean-Michel

Purpose: To assess retrospectively the clinical outcome in anal cancer patients, with lymph node involvement, treated with split-course radiation therapy and receiving a boost through external beam radiation therapy (EBRT) or brachytherapy (BCT). Methods and Materials: From 2000 to 2005, among 229 patients with invasive nonmetastatic anal squamous cell carcinoma, a selected group of 99 patients, with lymph node involvement, was studied. Tumor staging reported was T1 in 4 patients, T2 in 16 patients, T3 in 49 patients, T4 in 16 patients, and T unknown in 14 patients and as N1 in 67 patients and N2/N3 in 32 patients. Patientsmore » underwent a first course of EBRT (mean dose, 45.1 Gy) followed by a boost (mean dose, 18 Gy) using EBRT (50 patients) or BCT (49 patients). All characteristics of patients and tumors were well balanced between the BCT and EBRT groups. Prognostic factors of cumulative rate of local recurrence (CRLR), cumulative rate of distant (including nodal) recurrence (CRDR), colostomy-free survival (CFS) rate, and overall survival (OS) rate were analyzed for the overall population and according to the nodal status classification. Results: The median follow-up was 71.5 months. The 5-year CRLR, CRDR, CFS rate, and OS rate were 21%, 19%, 63%, and 74.4%, respectively. In the overall population, the type of node involvement (N1 vs N2/N3) was the unique independent prognostic factor for CRLR. In N1 patients, by use of multivariate analysis, BCT boost was the unique prognostic factor for CRLR (4% for BCT vs 31% for EBRT; hazard ratio, 0.08; P=.042). No studied factors were significantly associated with CRDR, CFS, and OS. No difference with regard to boost technique and any other factor studied was observed in N2/N3 patients for any kind of recurrence. Conclusion: In anal cancer, even in the case of initial perirectal node invasion, BCT boost is superior to EBRT boost for CRLR, without an influence on OS, suggesting that N1 status should not be a contraindication to use of a BCT boost technique, as well as emphasizing the important of investigating the benefit of BCT boost in prospective randomized trials.« less

Modelling and Simulation of Grid Connected SPV System with Active Power Filtering Features

NASA Astrophysics Data System (ADS)

Saroha, Jaipal; Pandove, Gitanjali; Singh, Mukhtiar

2017-09-01

In this paper, the detailed simulation studies for a grid connected solar photovoltaic system (SPV) have been presented. The power electronics devices like DC-DC boost converter and grid interfacing inverter are most important components of proposed system. Here, the DC-DC boost converter is controlled to extract maximum power out of SPV under different irradiation levels, while the grid interfacing inverter is utilized to evacuate the active power and feed it into grid at synchronized voltage and frequency. Moreover, the grid interfacing inverter is also controlled to sort out the issues related to power quality by compensating the reactive power and harmonics current component of nearby load at point of common coupling. Besides, detailed modeling of various component utilized in proposed system is also presented. Finally, extensive simulations have been performed under different irradiation levels with various kinds of load to validate the aforementioned claims. The overall system design and simulation have been performed by using Sim Power System toolbox available in the library of MATLAB.

How to Boost Power House Efficiency

ERIC Educational Resources Information Center

Gardner, John C.

1977-01-01

A study of a university power plant and its efficiency determined the total available steam generating capacity of the existing boilers and the physical conditions that were limiting that capacity. (Author/MLF)

Distributed control system for parallel-connected DC boost converters

DOEpatents

Goldsmith, Steven

2017-08-15

The disclosed invention is a distributed control system for operating a DC bus fed by disparate DC power sources that service a known or unknown load. The voltage sources vary in v-i characteristics and have time-varying, maximum supply capacities. Each source is connected to the bus via a boost converter, which may have different dynamic characteristics and power transfer capacities, but are controlled through PWM. The invention tracks the time-varying power sources and apportions their power contribution while maintaining the DC bus voltage within the specifications. A central digital controller solves the steady-state system for the optimal duty cycle settings that achieve a desired power supply apportionment scheme for a known or predictable DC load. A distributed networked control system is derived from the central system that utilizes communications among controllers to compute a shared estimate of the unknown time-varying load through shared bus current measurements and bus voltage measurements.

High Step-Up DC—DC Converter for AC Photovoltaic Module with MPPT Control

NASA Astrophysics Data System (ADS)

Sundar, Govindasamy; Karthick, Narashiman; Rama Reddy, Sasi

2014-08-01

This paper presents the high gain step-up BOOST converter which is essential to step up the low output voltage from PV panel to the high voltage according to the requirement of the application. In this paper a high gain BOOST converter with coupled inductor technique is proposed with the MPPT control. Without extreme duty ratios and the numerous turns-ratios of a coupled inductor this converter achieves a high step-up voltage-conversion ratio and the leakage energy of the coupled inductor is efficiently recycled to the load. MPPT control used to extract the maximum power from PV panel by controlling the Duty ratio of the converter. The PV panel, BOOST converter and the MPPT are modeled using Sim Power System blocks in MATLAB/SIMULINK environment. The prototype model of the proposed converter has been implemented with the maximum measured efficiency is up to 95.4% and full-load efficiency is 93.1%.

Impedance Matching Antenna-Integrated High-Efficiency Energy Harvesting Circuit

PubMed Central

Shinki, Yuharu; Shibata, Kyohei; Mansour, Mohamed

2017-01-01

This paper describes the design of a high-efficiency energy harvesting circuit with an integrated antenna. The circuit is composed of series resonance and boost rectifier circuits for converting radio frequency power into boosted direct current (DC) voltage. The measured output DC voltage is 5.67 V for an input of 100 mV at 900 MHz. Antenna input impedance matching is optimized for greater efficiency and miniaturization. The measured efficiency of this antenna-integrated energy harvester is 60% for −4.85 dBm input power and a load resistance equal to 20 kΩ at 905 MHz. PMID:28763043

Impedance Matching Antenna-Integrated High-Efficiency Energy Harvesting Circuit.

PubMed

Shinki, Yuharu; Shibata, Kyohei; Mansour, Mohamed; Kanaya, Haruichi

2017-08-01

This paper describes the design of a high-efficiency energy harvesting circuit with an integrated antenna. The circuit is composed of series resonance and boost rectifier circuits for converting radio frequency power into boosted direct current (DC) voltage. The measured output DC voltage is 5.67 V for an input of 100 mV at 900 MHz. Antenna input impedance matching is optimized for greater efficiency and miniaturization. The measured efficiency of this antenna-integrated energy harvester is 60% for -4.85 dBm input power and a load resistance equal to 20 kΩ at 905 MHz.

AlignerBoost: A Generalized Software Toolkit for Boosting Next-Gen Sequencing Mapping Accuracy Using a Bayesian-Based Mapping Quality Framework.

PubMed

Zheng, Qi; Grice, Elizabeth A

2016-10-01

Accurate mapping of next-generation sequencing (NGS) reads to reference genomes is crucial for almost all NGS applications and downstream analyses. Various repetitive elements in human and other higher eukaryotic genomes contribute in large part to ambiguously (non-uniquely) mapped reads. Most available NGS aligners attempt to address this by either removing all non-uniquely mapping reads, or reporting one random or "best" hit based on simple heuristics. Accurate estimation of the mapping quality of NGS reads is therefore critical albeit completely lacking at present. Here we developed a generalized software toolkit "AlignerBoost", which utilizes a Bayesian-based framework to accurately estimate mapping quality of ambiguously mapped NGS reads. We tested AlignerBoost with both simulated and real DNA-seq and RNA-seq datasets at various thresholds. In most cases, but especially for reads falling within repetitive regions, AlignerBoost dramatically increases the mapping precision of modern NGS aligners without significantly compromising the sensitivity even without mapping quality filters. When using higher mapping quality cutoffs, AlignerBoost achieves a much lower false mapping rate while exhibiting comparable or higher sensitivity compared to the aligner default modes, therefore significantly boosting the detection power of NGS aligners even using extreme thresholds. AlignerBoost is also SNP-aware, and higher quality alignments can be achieved if provided with known SNPs. AlignerBoost's algorithm is computationally efficient, and can process one million alignments within 30 seconds on a typical desktop computer. AlignerBoost is implemented as a uniform Java application and is freely available at https://github.com/Grice-Lab/AlignerBoost.

High-frequency high-voltage high-power DC-to-DC converters

NASA Astrophysics Data System (ADS)

Wilson, T. G.; Owen, H. A., Jr.; Wilson, P. M.

1981-07-01

The current and voltage waveshapes associated with the power transitor and the power diode in an example current-or-voltage step-up (buck-boost) converter were analyzed to highlight the problems and possible tradeoffs involved in the design of high voltage high power converters operating at switching frequencies in the range of 100 Khz. Although the fast switching speeds of currently available power diodes and transistors permit converter operation at high switching frequencies, the resulting time rates of changes of current coupled with parasitic inductances in series with the semiconductor switches, produce large repetitive voltage transients across the semiconductor switches, potentially far in excess of the device voltage ratings. The need is established for semiconductor switch protection circuitry to control the peak voltages appearing across the semiconductor switches, as well as to provide the waveshaping action require for a given semiconductor device. The possible tradeoffs, as well as the factors affecting the tradeoffs that must be considered in order to maximize the efficiency of the converters are enumerated.

High-frequency high-voltage high-power DC-to-DC converters

NASA Technical Reports Server (NTRS)

Wilson, T. G.; Owen, H. A., Jr.; Wilson, P. M.

1981-01-01

The current and voltage waveshapes associated with the power transitor and the power diode in an example current-or-voltage step-up (buck-boost) converter were analyzed to highlight the problems and possible tradeoffs involved in the design of high voltage high power converters operating at switching frequencies in the range of 100 Khz. Although the fast switching speeds of currently available power diodes and transistors permit converter operation at high switching frequencies, the resulting time rates of changes of current coupled with parasitic inductances in series with the semiconductor switches, produce large repetitive voltage transients across the semiconductor switches, potentially far in excess of the device voltage ratings. The need is established for semiconductor switch protection circuitry to control the peak voltages appearing across the semiconductor switches, as well as to provide the waveshaping action require for a given semiconductor device. The possible tradeoffs, as well as the factors affecting the tradeoffs that must be considered in order to maximize the efficiency of the converters are enumerated.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Chen; Perez, Danny; Voter, Arthur F.

Hyperdynamics is a powerful method to significantly extend the time scales amenable to molecular dynamics simulation of infrequent events. One outstanding challenge, however, is the development of the so-called bias potential required by the method. In this work, we design a bias potential using information about all minimum energy pathways (MEPs) out of the current state. While this approach is not suitable for use in an actual hyperdynamics simulation, because the pathways are generally not known in advance, it allows us to show that it is possible to come very close to the theoretical boost limit of hyperdynamics while maintainingmore » high accuracy. We demonstrate this by applying this MEP-based hyperdynamics (MEP-HD) to metallic surface diffusion systems. In most cases, MEP-HD gives boost factors that are orders of magnitude larger than the best existing bias potential, indicating that further development of hyperdynamics bias potentials could have a significant payoff. Lastly, we discuss potential practical uses of MEP-HD, including the possibility of developing MEP-HD into a true hyperdynamics.« less

An empirical comparison of several recent epistatic interaction detection methods.

PubMed

Wang, Yue; Liu, Guimei; Feng, Mengling; Wong, Limsoon

2011-11-01

Many new methods have recently been proposed for detecting epistatic interactions in GWAS data. There is, however, no in-depth independent comparison of these methods yet. Five recent methods-TEAM, BOOST, SNPHarvester, SNPRuler and Screen and Clean (SC)-are evaluated here in terms of power, type-1 error rate, scalability and completeness. In terms of power, TEAM performs best on data with main effect and BOOST performs best on data without main effect. In terms of type-1 error rate, TEAM and BOOST have higher type-1 error rates than SNPRuler and SNPHarvester. SC does not control type-1 error rate well. In terms of scalability, we tested the five methods using a dataset with 100 000 SNPs on a 64 bit Ubuntu system, with Intel (R) Xeon(R) CPU 2.66 GHz, 16 GB memory. TEAM takes ~36 days to finish and SNPRuler reports heap allocation problems. BOOST scales up to 100 000 SNPs and the cost is much lower than that of TEAM. SC and SNPHarvester are the most scalable. In terms of completeness, we study how frequently the pruning techniques employed by these methods incorrectly prune away the most significant epistatic interactions. We find that, on average, 20% of datasets without main effect and 60% of datasets with main effect are pruned incorrectly by BOOST, SNPRuler and SNPHarvester. The software for the five methods tested are available from the URLs below. TEAM: http://csbio.unc.edu/epistasis/download.php BOOST: http://ihome.ust.hk/~eeyang/papers.html. SNPHarvester: http://bioinformatics.ust.hk/SNPHarvester.html. SNPRuler: http://bioinformatics.ust.hk/SNPRuler.zip. Screen and Clean: http://wpicr.wpic.pitt.edu/WPICCompGen/. wangyue@nus.edu.sg.

JPRS Report, China.

DTIC Science & Technology

1988-12-19

Statistics [CEI Database 4 Nov] 17 Construction Bank Checks on Investment Loans [XINHUA] 17 Gold Output Rising 10 Percent Annually [CHINA DAILY 8...Industrial Output for September [CEI Database 11 Nov] 23 Energy Industry Grows Steadily in 1988 [CEI Database 11 Nov] 23 Government Plans To Boost...Plastics Industry [XINHUA] 24 Chongqing’s Industrial Output Increases [XINHUA] 24 Haikou Boosts Power Industry [CEI Database 27 Oct] 24 Jilin

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, Hyeokjin; Chen, Hua; Maksimovic, Dragan

An experimental 30 kW boost composite converter is described in this paper. The composite converter architecture, which consists of a buck module, a boost module, and a dual active bridge module that operates as a DC transformer (DCX), leads to substantial reductions in losses at partial power points, and to significant improvements in weighted efficiency in applications that require wide variations in power and conversion ratio. A comprehensive loss model is developed, accounting for semiconductor conduction and switching losses, capacitor losses, as well as dc and ac losses in magnetic components. Based on the developed loss model, the module andmore » system designs are optimized to maximize efficiency at a 50% power point. Experimental results for the 30 kW prototype demonstrate 98.5%peak efficiency, very high efficiency over wide ranges of power and voltage conversion ratios, as well as excellent agreements between model predictions and measured efficiency curves.« less

Modeling of switching regulator power stages with and without zero-inductor-current dwell time

NASA Technical Reports Server (NTRS)

Lee, F. C. Y.; Yu, Y.

1979-01-01

State-space techniques are employed to derive accurate models for the three basic switching converter power stages: buck, boost, and buck/boost operating with and without zero-inductor-current dwell time. A generalized procedure is developed which treats the continuous-inductor-current mode without dwell time as a special case of the discontinuous-current mode when the dwell time vanishes. Abrupt changes of system behavior, including a reduction of the system order when the dwell time appears, are shown both analytically and experimentally. Merits resulting from the present modeling technique in comparison with existing modeling techniques are illustrated.

Implementation of fuzzy-sliding mode based control of a grid connected photovoltaic system.

PubMed

Menadi, Abdelkrim; Abdeddaim, Sabrina; Ghamri, Ahmed; Betka, Achour

2015-09-01

The present work describes an optimal operation of a small scale photovoltaic system connected to a micro-grid, based on both sliding mode and fuzzy logic control. Real time implementation is done through a dSPACE 1104 single board, controlling a boost chopper on the PV array side and a voltage source inverter (VSI) on the grid side. The sliding mode controller tracks permanently the maximum power of the PV array regardless of atmospheric condition variations, while The fuzzy logic controller (FLC) regulates the DC-link voltage, and ensures via current control of the VSI a quasi-total transit of the extracted PV power to the grid under a unity power factor operation. Simulation results, carried out via Matlab-Simulink package were approved through experiment, showing the effectiveness of the proposed control techniques. Copyright © 2015. Published by Elsevier Ltd.

All-fiber high-power monolithic femtosecond laser at 1.59 µm with 63-fs pulse width

NASA Astrophysics Data System (ADS)

Hekmat, M. J.; Omoomi, M.; Gholami, A.; Yazdabadi, A. Bagheri; Abdollahi, M.; Hamidnejad, E.; Ebrahimi, A.; Normohamadi, H.

2018-01-01

In this research, by adopting an alternative novel approach to ultra-short giant pulse generation which basically originated from difficulties with traditional employed methods, an optimized Er/Yb co-doped double-clad fiber amplifier is applied to boost output average power of single-mode output pulses to a high level of 2-W at 1.59-µm central wavelength. Output pulses of approximately 63-fs pulse width at 52-MHz repetition rate are obtained in an all-fiber monolithic laser configuration. The idea of employing parabolic pulse amplification for stretching output pulses together with high-power pulse amplification using Er/Yb co-doped active fibers for compressing and boosting output average power plays crucial role in obtaining desired results. The proposed configuration enjoys massive advantages over previously reported literature which make it well-suited for high-power precision applications such as medical surgery. Detailed dynamics of pulse stretching and compressing in active fibers with different GVD parameters are numerically and experimentally investigated.

Experimental Simulation of Turbine-Exhaust Oxygen Recovery

NASA Technical Reports Server (NTRS)

Clark, Jim A.; Branch, Ryan W.

2004-01-01

In some liquid-propellant rocket engines, the liquid-oxygen boost pump is driven by a turbine that is powered by high-pressure gaseous oxygen. Once it exits the turbine, this gaseous oxygen can be salvaged by injecting it into the subcooled liquid oxygen exiting the boost pump. If the main LOX pump is to function correctly under these circumstances, complete condensation of the gaseous oxygen must quickly follow its injection into the boost-pump discharge. The current investigation uses steam and water in a simple rig that allows the condensation process to be visualized and quantified. This paper offers dimensionless-parameter correlations of the data and trends observed.

A High Efficiency Boost Converter with MPPT Scheme for Low Voltage Thermoelectric Energy Harvesting

NASA Astrophysics Data System (ADS)

Guan, Mingjie; Wang, Kunpeng; Zhu, Qingyuan; Liao, Wei-Hsin

2016-11-01

Using thermoelectric elements to harvest energy from heat has been of great interest during the last decade. This paper presents a direct current-direct current (DC-DC) boost converter with a maximum power point tracking (MPPT) scheme for low input voltage thermoelectric energy harvesting applications. Zero current switch technique is applied in the proposed MPPT scheme. Theoretical analysis on the converter circuits is explored to derive the equations for parameters needed in the design of the boost converter. Simulations and experiments are carried out to verify the theoretical analysis and equations. A prototype of the designed converter is built using discrete components and a low-power microcontroller. The results show that the designed converter can achieve a high efficiency at low input voltage. The experimental efficiency of the designed converter is compared with a commercial converter solution. It is shown that the designed converter has a higher efficiency than the commercial solution in the considered voltage range.

Perforin and gamma interferon expression are required for CD4+ and CD8+ T-cell-dependent protective immunity against a human parasite, Trypanosoma cruzi, elicited by heterologous plasmid DNA prime-recombinant adenovirus 5 boost vaccination.

PubMed

de Alencar, Bruna C G; Persechini, Pedro M; Haolla, Filipe A; de Oliveira, Gabriel; Silverio, Jaline C; Lannes-Vieira, Joseli; Machado, Alexandre V; Gazzinelli, Ricardo T; Bruna-Romero, Oscar; Rodrigues, Mauricio M

2009-10-01

A heterologous prime-boost strategy using plasmid DNA, followed by replication-defective recombinant adenovirus 5, is being proposed as a powerful way to elicit CD4(+) and CD8(+) T-cell-mediated protective immunity against intracellular pathogens. We confirmed this concept and furthered existing research by providing evidence that the heterologous prime-boost regimen using the gene encoding amastigote surface protein 2 elicited CD4(+) and CD8(+) T-cell-mediated protective immunity (reduction of acute parasitemia and prolonged survival) against experimental infection with Trypanosoma cruzi. Protective immunity correlated with the presence of in vivo antigen-specific cytotoxic activity prior to challenge. Based on this, our second goal was to determine the outcome of infection after heterologous prime-boost immunization of perforin-deficient mice. These mice were highly susceptible to infection. A detailed analysis of the cell-mediated immune responses in immunized perforin-deficient mice showed an impaired gamma interferon (IFN-gamma) secretion by immune spleen cells upon restimulation in vitro with soluble recombinant antigen. In spite of a normal numeric expansion, specific CD8(+) T cells presented several functional defects detected in vivo (cytotoxicity) and in vitro (simultaneous expression of CD107a/IFN-gamma or IFN-gamma/tumor necrosis factor alpha) paralleled by a decreased expression of CD44 and KLRG-1. Our final goal was to determine the importance of IFN-gamma in the presence of highly cytotoxic T cells. Vaccinated IFN-gamma-deficient mice developed highly cytotoxic cells but failed to develop any protective immunity. Our study thus demonstrated a role for perforin and IFN-gamma in a number of T-cell-mediated effector functions and in the antiparasitic immunity generated by a heterologous plasmid DNA prime-adenovirus boost vaccination strategy.

Perforin and Gamma Interferon Expression Are Required for CD4+ and CD8+ T-Cell-Dependent Protective Immunity against a Human Parasite, Trypanosoma cruzi, Elicited by Heterologous Plasmid DNA Prime-Recombinant Adenovirus 5 Boost Vaccination▿

PubMed Central

de Alencar, Bruna C. G.; Persechini, Pedro M.; Haolla, Filipe A.; de Oliveira, Gabriel; Silverio, Jaline C.; Lannes-Vieira, Joseli; Machado, Alexandre V.; Gazzinelli, Ricardo T.; Bruna-Romero, Oscar; Rodrigues, Mauricio M.

2009-01-01

A heterologous prime-boost strategy using plasmid DNA, followed by replication-defective recombinant adenovirus 5, is being proposed as a powerful way to elicit CD4+ and CD8+ T-cell-mediated protective immunity against intracellular pathogens. We confirmed this concept and furthered existing research by providing evidence that the heterologous prime-boost regimen using the gene encoding amastigote surface protein 2 elicited CD4+ and CD8+ T-cell-mediated protective immunity (reduction of acute parasitemia and prolonged survival) against experimental infection with Trypanosoma cruzi. Protective immunity correlated with the presence of in vivo antigen-specific cytotoxic activity prior to challenge. Based on this, our second goal was to determine the outcome of infection after heterologous prime-boost immunization of perforin-deficient mice. These mice were highly susceptible to infection. A detailed analysis of the cell-mediated immune responses in immunized perforin-deficient mice showed an impaired gamma interferon (IFN-γ) secretion by immune spleen cells upon restimulation in vitro with soluble recombinant antigen. In spite of a normal numeric expansion, specific CD8+ T cells presented several functional defects detected in vivo (cytotoxicity) and in vitro (simultaneous expression of CD107a/IFN-γ or IFN-γ/tumor necrosis factor alpha) paralleled by a decreased expression of CD44 and KLRG-1. Our final goal was to determine the importance of IFN-γ in the presence of highly cytotoxic T cells. Vaccinated IFN-γ-deficient mice developed highly cytotoxic cells but failed to develop any protective immunity. Our study thus demonstrated a role for perforin and IFN-γ in a number of T-cell-mediated effector functions and in the antiparasitic immunity generated by a heterologous plasmid DNA prime-adenovirus boost vaccination strategy. PMID:19651871

Analysis and design of a standardized control module for switching regulators

NASA Astrophysics Data System (ADS)

Lee, F. C.; Mahmoud, M. F.; Yu, Y.; Kolecki, J. C.

1982-07-01

Three basic switching regulators: buck, boost, and buck/boost, employing a multiloop standardized control module (SCM) were characterized by a common small signal block diagram. Employing the unified model, regulator performances such as stability, audiosusceptibility, output impedance, and step load transient are analyzed and key performance indexes are expressed in simple analytical forms. More importantly, the performance characteristics of all three regulators are shown to enjoy common properties due to the unique SCM control scheme which nullifies the positive zero and provides adaptive compensation to the moving poles of the boost and buck/boost converters. This allows a simple unified design procedure to be devised for selecting the key SCM control parameters for an arbitrarily given power stage configuration and parameter values, such that all regulator performance specifications can be met and optimized concurrently in a single design attempt.

Boosting Learning Algorithm for Stock Price Forecasting

NASA Astrophysics Data System (ADS)

Wang, Chengzhang; Bai, Xiaoming

2018-03-01

To tackle complexity and uncertainty of stock market behavior, more studies have introduced machine learning algorithms to forecast stock price. ANN (artificial neural network) is one of the most successful and promising applications. We propose a boosting-ANN model in this paper to predict the stock close price. On the basis of boosting theory, multiple weak predicting machines, i.e. ANNs, are assembled to build a stronger predictor, i.e. boosting-ANN model. New error criteria of the weak studying machine and rules of weights updating are adopted in this study. We select technical factors from financial markets as forecasting input variables. Final results demonstrate the boosting-ANN model works better than other ones for stock price forecasting.

High power narrow-band fiber-based ASE source.

PubMed

Schmidt, O; Rekas, M; Wirth, C; Rothhardt, J; Rhein, S; Kliner, A; Strecker, M; Schreiber, T; Limpert, J; Eberhardt, R; Tünnermann, A

2011-02-28

In this paper we describe a high power narrow-band amplified spontaneous emission (ASE) light source at 1030 nm center wavelength generated in an Yb-doped fiber-based experimental setup. By cutting a small region out of a broadband ASE spectrum using two fiber Bragg gratings a strongly constrained bandwidth of 12±2 pm (3.5±0.6 GHz) is formed. A two-stage high power fiber amplifier system is used to boost the output power up to 697 W with a measured beam quality of M2≤1.34. In an additional experiment we demonstrate a stimulated Brillouin scattering (SBS) suppression of at least 17 dB (theoretically predicted ~20 dB), which is only limited by the dynamic range of the measurement and not by the onset of SBS when using the described light source. The presented narrow-band ASE source could be of great interest for brightness scaling applications by beam combination, where SBS is known as a limiting factor.

AlignerBoost: A Generalized Software Toolkit for Boosting Next-Gen Sequencing Mapping Accuracy Using a Bayesian-Based Mapping Quality Framework

PubMed Central

Zheng, Qi; Grice, Elizabeth A.

2016-01-01

Accurate mapping of next-generation sequencing (NGS) reads to reference genomes is crucial for almost all NGS applications and downstream analyses. Various repetitive elements in human and other higher eukaryotic genomes contribute in large part to ambiguously (non-uniquely) mapped reads. Most available NGS aligners attempt to address this by either removing all non-uniquely mapping reads, or reporting one random or "best" hit based on simple heuristics. Accurate estimation of the mapping quality of NGS reads is therefore critical albeit completely lacking at present. Here we developed a generalized software toolkit "AlignerBoost", which utilizes a Bayesian-based framework to accurately estimate mapping quality of ambiguously mapped NGS reads. We tested AlignerBoost with both simulated and real DNA-seq and RNA-seq datasets at various thresholds. In most cases, but especially for reads falling within repetitive regions, AlignerBoost dramatically increases the mapping precision of modern NGS aligners without significantly compromising the sensitivity even without mapping quality filters. When using higher mapping quality cutoffs, AlignerBoost achieves a much lower false mapping rate while exhibiting comparable or higher sensitivity compared to the aligner default modes, therefore significantly boosting the detection power of NGS aligners even using extreme thresholds. AlignerBoost is also SNP-aware, and higher quality alignments can be achieved if provided with known SNPs. AlignerBoost’s algorithm is computationally efficient, and can process one million alignments within 30 seconds on a typical desktop computer. AlignerBoost is implemented as a uniform Java application and is freely available at https://github.com/Grice-Lab/AlignerBoost. PMID:27706155

Adaptive super-twisting sliding mode control for a three-phase single-stage grid-connected differential boost inverter based photovoltaic system.

PubMed

Pati, Akshaya K; Sahoo, N C

2017-07-01

This paper presents an adaptive super-twisting sliding mode control (STC) along with double-loop control for voltage tracking performance of three-phase differential boost inverter and DC-link capacitor voltage regulation in grid-connected PV system. The effectiveness of the proposed control strategies are demonstrated under realistic scenarios such as variations in solar insolation, load power demand, grid voltage, and transition from grid-connected to standalone mode etc. Additional supplementary power quality control functions such as harmonic compensation, and reactive power management are also investigated with the proposed control strategy. The results are compared with conventional proportional-integral controller, and PWM sliding mode controller. The system performance is evaluated in simulation and in real-time. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

Users guide for guidance and control Launch and Abort Simulation for Spacecraft (LASS), volume 1

NASA Technical Reports Server (NTRS)

Havig, T. F.; Backman, H. D.

1972-01-01

The mathematical models and computer program which are used to implement LASS are described. The computer program provides for a simulation of boost to orbit and abort capability from boost trajectories to a prescribed target. The abort target provides a decision point for engine shutdown from which the vehicle coasts to the vicinity of the selected abort recovery site. The simulation is a six degree of freedom simulation describing a rigid body. The vehicle is influenced by forces and moments from nondistributed aerodynamics. An adaptive autopilot is provided to control vehicle attitudes during powered and unpowered flight. A conventional autopilot is provided for study of vehicle during powered flight.

Boosting jet power in black hole spacetimes.

PubMed

Neilsen, David; Lehner, Luis; Palenzuela, Carlos; Hirschmann, Eric W; Liebling, Steven L; Motl, Patrick M; Garrett, Travis

2011-08-02

The extraction of rotational energy from a spinning black hole via the Blandford-Znajek mechanism has long been understood as an important component in models to explain energetic jets from compact astrophysical sources. Here we show more generally that the kinetic energy of the black hole, both rotational and translational, can be tapped, thereby producing even more luminous jets powered by the interaction of the black hole with its surrounding plasma. We study the resulting Poynting jet that arises from single boosted black holes and binary black hole systems. In the latter case, we find that increasing the orbital angular momenta of the system and/or the spins of the individual black holes results in an enhanced Poynting flux.

Thermal Management and Packaging Reliability (Text Version) |

Science.gov Websites

Transportation Research | NREL Thermal Management and Packaging Reliability (Text Version ) Thermal Management and Packaging Reliability (Text Version) Learn how NREL's thermal management and ;Boosting Thermal Management & Reliability of Vehicle Power Electronics." Better power electronics

Distinguishing Positive Selection From Neutral Evolution: Boosting the Performance of Summary Statistics

PubMed Central

Lin, Kao; Li, Haipeng; Schlötterer, Christian; Futschik, Andreas

2011-01-01

Summary statistics are widely used in population genetics, but they suffer from the drawback that no simple sufficient summary statistic exists, which captures all information required to distinguish different evolutionary hypotheses. Here, we apply boosting, a recent statistical method that combines simple classification rules to maximize their joint predictive performance. We show that our implementation of boosting has a high power to detect selective sweeps. Demographic events, such as bottlenecks, do not result in a large excess of false positives. A comparison to other neutrality tests shows that our boosting implementation performs well compared to other neutrality tests. Furthermore, we evaluated the relative contribution of different summary statistics to the identification of selection and found that for recent sweeps integrated haplotype homozygosity is very informative whereas older sweeps are better detected by Tajima's π. Overall, Watterson's θ was found to contribute the most information for distinguishing between bottlenecks and selection. PMID:21041556

User's design handbook for a Standardized Control Module (SCM) for DC to DC Converters, volume 2

NASA Technical Reports Server (NTRS)

Lee, F. C.

1980-01-01

A unified design procedure is presented for selecting the key SCM control parameters for an arbitrarily given power stage configuration and parameter values, such that all regulator performance specifications can be met and optimized concurrently in a single design attempt. All key results and performance indices, for buck, boost, and buck/boost switching regulators which are relevant to SCM design considerations are included to facilitate frequent references.

Voltage-Boosting Driver For Switching Regulator

NASA Technical Reports Server (NTRS)

Trump, Ronald C.

1990-01-01

Driver circuit assures availability of 10- to 15-V gate-to-source voltage needed to turn on n-channel metal oxide/semiconductor field-effect transistor (MOSFET) acting as switch in switching voltage regulator. Includes voltage-boosting circuit efficiently providing gate voltage 10 to 15 V above supply voltage. Contains no exotic parts and does not require additional power supply. Consists of NAND gate and dual voltage booster operating in conjunction with pulse-width modulator part of regulator.

Sliding mode control of direct coupled interleaved boost converter for fuel cell

NASA Astrophysics Data System (ADS)

Wang, W. Y.; Ding, Y. H.; Ke, X.; Ma, X.

2017-12-01

A three phase direct coupled interleaved boost converter (TP-DIBC) was recommended in this paper. This converter has a small unbalance current sharing among the branches of TP-DIBC. An adaptive control law sliding mode control (SMC) is designed for the TP-DIBC. The aim is to 1) reduce ripple output voltage, inductor current and regulate output voltage tightly 2) The total current carried by direct coupled interleaved boost converter (DIBC) must be equally shared between different parallel branches. The efficacy and robustness of the proposed TP-DIBC and adaptive SMC is confirmed via computer simulations using Matlab SimPower System Tools. The simulation result is in line with the expectation.

An Improved Power Quality BIBRED Converter-Based VSI-Fed BLDC Motor Drive

NASA Astrophysics Data System (ADS)

Singh, Bhim; Bist, Vashist

2014-01-01

This paper presents an IHQRR (integrated high-quality rectifier regulator) BIBRED (boost integrated buck rectifier energy storage DC-DC) converter-based VSI (voltage source inverter)-fed BLDC (brushless DC) motor drive. The speed control of BLDC motor is achieved by controlling the DC link voltage of the VSI using a single voltage sensor. This allows VSI to operate in fundamental frequency switching mode for electronic commutation of BLDC motor which reduces the switching losses due to high-frequency switching used in conventional approach of PWM (pulse width modulation)-based VSI-fed BLDC motor drive. A BIBRED converter is operated in a dual-DCM (discontinuous conduction mode) thus using a voltage follower approach for PFC (power factor correction) and DC link voltage control. The performance of the proposed drive is evaluated for improved power quality over a wide range of speed control and supply voltage variation for demonstrating the behavior of proposed drive. The power quality indices thus obtained are within the recommended limits by international PQ (power quality) standards such as IEC 61000-3-2.

An ultra-low power CMOS image sensor with on-chip energy harvesting and power management capability.

PubMed

Cevik, Ismail; Huang, Xiwei; Yu, Hao; Yan, Mei; Ay, Suat U

2015-03-06

An ultra-low power CMOS image sensor with on-chip energy harvesting and power management capability is introduced in this paper. The photodiode pixel array can not only capture images but also harvest solar energy. As such, the CMOS image sensor chip is able to switch between imaging and harvesting modes towards self-power operation. Moreover, an on-chip maximum power point tracking (MPPT)-based power management system (PMS) is designed for the dual-mode image sensor to further improve the energy efficiency. A new isolated P-well energy harvesting and imaging (EHI) pixel with very high fill factor is introduced. Several ultra-low power design techniques such as reset and select boosting techniques have been utilized to maintain a wide pixel dynamic range. The chip was designed and fabricated in a 1.8 V, 1P6M 0.18 µm CMOS process. Total power consumption of the imager is 6.53 µW for a 96 × 96 pixel array with 1 V supply and 5 fps frame rate. Up to 30 μW of power could be generated by the new EHI pixels. The PMS is capable of providing 3× the power required during imaging mode with 50% efficiency allowing energy autonomous operation with a 72.5% duty cycle.

An Ultra-Low Power CMOS Image Sensor with On-Chip Energy Harvesting and Power Management Capability

PubMed Central

Cevik, Ismail; Huang, Xiwei; Yu, Hao; Yan, Mei; Ay, Suat U.

2015-01-01

An ultra-low power CMOS image sensor with on-chip energy harvesting and power management capability is introduced in this paper. The photodiode pixel array can not only capture images but also harvest solar energy. As such, the CMOS image sensor chip is able to switch between imaging and harvesting modes towards self-power operation. Moreover, an on-chip maximum power point tracking (MPPT)-based power management system (PMS) is designed for the dual-mode image sensor to further improve the energy efficiency. A new isolated P-well energy harvesting and imaging (EHI) pixel with very high fill factor is introduced. Several ultra-low power design techniques such as reset and select boosting techniques have been utilized to maintain a wide pixel dynamic range. The chip was designed and fabricated in a 1.8 V, 1P6M 0.18 µm CMOS process. Total power consumption of the imager is 6.53 µW for a 96 × 96 pixel array with 1 V supply and 5 fps frame rate. Up to 30 μW of power could be generated by the new EHI pixels. The PMS is capable of providing 3× the power required during imaging mode with 50% efficiency allowing energy autonomous operation with a 72.5% duty cycle. PMID:25756863

Design considerations for remotely piloted, high-altitude airplanes powered by microwave energy

NASA Technical Reports Server (NTRS)

Morris, C. E. K., Jr.

1984-01-01

Several types of systems have been considered in a design study of unmanned, microwave-powered, long-endurance, high-altitude airplanes. The study includes vehicles that use power from a continuously transmitted beam and other aircraft that receive intermittent power during cycles of boost-glide flight. Simple design algorithms are presented. Examples of sizing and performance analyses are used to suggest design-procedure guidelines.

Power Enhancement in High Dimensional Cross-Sectional Tests

PubMed Central

Fan, Jianqing; Liao, Yuan; Yao, Jiawei

2016-01-01

We propose a novel technique to boost the power of testing a high-dimensional vector H : θ = 0 against sparse alternatives where the null hypothesis is violated only by a couple of components. Existing tests based on quadratic forms such as the Wald statistic often suffer from low powers due to the accumulation of errors in estimating high-dimensional parameters. More powerful tests for sparse alternatives such as thresholding and extreme-value tests, on the other hand, require either stringent conditions or bootstrap to derive the null distribution and often suffer from size distortions due to the slow convergence. Based on a screening technique, we introduce a “power enhancement component”, which is zero under the null hypothesis with high probability, but diverges quickly under sparse alternatives. The proposed test statistic combines the power enhancement component with an asymptotically pivotal statistic, and strengthens the power under sparse alternatives. The null distribution does not require stringent regularity conditions, and is completely determined by that of the pivotal statistic. As specific applications, the proposed methods are applied to testing the factor pricing models and validating the cross-sectional independence in panel data models. PMID:26778846

Boosted Regression Tree Models to Explain Watershed Nutrient Concentrations and Biological Condition

EPA Science Inventory

Boosted regression tree (BRT) models were developed to quantify the nonlinear relationships between landscape variables and nutrient concentrations in a mesoscale mixed land cover watershed during base-flow conditions. Factors that affect instream biological components, based on ...

A 190 mV start-up and 59.2% efficiency CMOS gate boosting voltage doubler charge pump in 0.18 µm standard CMOS process for energy harvesting

NASA Astrophysics Data System (ADS)

Yoshida, Minori; Miyaji, Kousuke

2018-04-01

A start-up charge pump circuit for an extremely low input voltage (V IN) is proposed and demonstrated. The proposed circuit uses an inverter level shifter to generate a 2V IN voltage swing to the gate of both main NMOS and PMOS power transistors in a charge pump to reduce the channel resistance. The proposed circuit is fully implemented in a standard 0.18 µm CMOS process, and the measurement result shows that a minimum input voltage of 190 mV is achieved and output power increases by 181% compared with the conventional forward-body-bias scheme at a 300 mV input voltage. The proposed scheme achieves a maximum efficiency of 59.2% when the input voltage is 390 mV and the output current is 320 nA. The proposed circuit is suitable as a start-up circuit in ultralow power energy harvesting power management applications to boost-up from below threshold voltage.

Chemical rules on the assessment of antioxidant potential in food and food additives aimed at reducing oxidative stress and neurodegeneration.

PubMed

Franco, Rafael; Martínez-Pinilla, Eva

2017-11-15

Antioxidants (aOXs) enlarge the useful life of products consumed by humans. Life requires oxidation of glucose/fatty acids and, therefore, "antioxidant" becomes an oxymoron when trying to define benefits in organisms living in an oxygen-rich atmosphere. According to basic physico-chemical principles, the in vivo aOX potential of food supplements is negligible when compared with the main aOX molecules in the animal Kingdom: glucose and fatty acids. Thus, the aOX assumption to improve life-quality is misleading as oxidative stress and exacerbation occur when oxidant foods (e.g. fava beans) are consumed. Evolution produced potent detoxification mechanisms to handle these situations. When age/genetic/environmental factors negatively impact on detoxification mechanisms, nutrition helps on providing metabolites/precursors needed for boosting innate resources. Ambiguous techniques that attempt to measure in vivo aOX power, should give way to measuring the level of supplements and their metabolites in body fluids/tissues, and to measure the efficacy on antioxidant boosting REDOX pathways. Copyright © 2017 Elsevier Ltd. All rights reserved.

Boosting structured additive quantile regression for longitudinal childhood obesity data.

PubMed

Fenske, Nora; Fahrmeir, Ludwig; Hothorn, Torsten; Rzehak, Peter; Höhle, Michael

2013-07-25

Childhood obesity and the investigation of its risk factors has become an important public health issue. Our work is based on and motivated by a German longitudinal study including 2,226 children with up to ten measurements on their body mass index (BMI) and risk factors from birth to the age of 10 years. We introduce boosting of structured additive quantile regression as a novel distribution-free approach for longitudinal quantile regression. The quantile-specific predictors of our model include conventional linear population effects, smooth nonlinear functional effects, varying-coefficient terms, and individual-specific effects, such as intercepts and slopes. Estimation is based on boosting, a computer intensive inference method for highly complex models. We propose a component-wise functional gradient descent boosting algorithm that allows for penalized estimation of the large variety of different effects, particularly leading to individual-specific effects shrunken toward zero. This concept allows us to flexibly estimate the nonlinear age curves of upper quantiles of the BMI distribution, both on population and on individual-specific level, adjusted for further risk factors and to detect age-varying effects of categorical risk factors. Our model approach can be regarded as the quantile regression analog of Gaussian additive mixed models (or structured additive mean regression models), and we compare both model classes with respect to our obesity data.

Modular high-voltage bias generator powered by dual-looped self-adaptive wireless power transmission.

PubMed

Xie, Kai; Huang, An-Feng; Li, Xiao-Ping; Guo, Shi-Zhong; Zhang, Han-Lu

2015-04-01

We proposed a modular high-voltage (HV) bias generator powered by a novel transmitter-sharing inductive coupled wireless power transmission technology, aimed to extend the generator's flexibility and configurability. To solve the problems caused through an uncertain number of modules, a dual-looped self-adaptive control method is proposed that is capable of tracking resonance frequency while maintaining a relatively stable induction voltage for each HV module. The method combines a phase-locked loop and a current feedback loop, which ensures an accurate resonance state and a relatively constant boost ratio for each module, simplifying the architecture of the boost stage and improving the total efficiency. The prototype was built and tested. The input voltage drop of each module is less than 14% if the module number varies from 3 to 10; resonance tracking is completed within 60 ms. The efficiency of the coupling structure reaches up to 95%, whereas the total efficiency approaches 73% for a rated output. Furthermore, this technology can be used in various multi-load wireless power supply applications.

The Type-2 Fuzzy Logic Controller-Based Maximum Power Point Tracking Algorithm and the Quadratic Boost Converter for Pv System

NASA Astrophysics Data System (ADS)

Altin, Necmi

2018-05-01

An interval type-2 fuzzy logic controller-based maximum power point tracking algorithm and direct current-direct current (DC-DC) converter topology are proposed for photovoltaic (PV) systems. The proposed maximum power point tracking algorithm is designed based on an interval type-2 fuzzy logic controller that has an ability to handle uncertainties. The change in PV power and the change in PV voltage are determined as inputs of the proposed controller, while the change in duty cycle is determined as the output of the controller. Seven interval type-2 fuzzy sets are determined and used as membership functions for input and output variables. The quadratic boost converter provides high voltage step-up ability without any reduction in performance and stability of the system. The performance of the proposed system is validated through MATLAB/Simulink simulations. It is seen that the proposed system provides high maximum power point tracking speed and accuracy even for fast changing atmospheric conditions and high voltage step-up requirements.

Design of a hybrid battery charger system fed by a wind-turbine and photovoltaic power generators.

PubMed

Chang Chien, Jia-Ren; Tseng, Kuo-Ching; Yan, Bo-Yi

2011-03-01

This paper is aimed to develop a digital signal processor (DSP) for controlling a solar cell and wind-turbine hybrid charging system. The DSP consists of solar cells, a wind turbine, a lead acid battery, and a buck-boost converter. The solar cells and wind turbine serve as the system's main power sources and the battery as an energy storage element. The output powers of solar cells and wind turbine have large fluctuations with the weather and climate conditions. These unstable powers can be adjusted by a buck-boost converter and thus the most suitable output powers can be obtained. This study designs a booster by using a dsPIC30F4011 digital signal controller as a core processor. The DSP is controlled by the perturbation and observation methods to obtain an effective energy circuit with a full 100 W charging system. Also, this DSP can, day and night, be easily controlled and charged by a simple program, which can change the state of the system to reach a flexible application based on the reading weather conditions.

Extremely high-power-density atmospheric-pressure thermal plasma jet generated by the nitrogen-boosted effect

NASA Astrophysics Data System (ADS)

Hanafusa, Hiroaki; Nakashima, Ryosuke; Nakano, Wataru; Higashi, Seiichiro

2018-06-01

In this study, the effect of N2 addition to an atmospheric-pressure Ar thermal plasma jet (TPJ) on ultrarapid heating was investigated. With increasing N2 flow rate, a boost of arc voltage to ∼36 V was observed, which significantly improved heating characteristics. As a result, a drastic power density increase from 10 to 125 kW/cm2 was achieved with the addition of 2.0 L/min N2 to 3.0 L/min Ar. The results of optical emission analysis and heating characteristics evaluation implied that dissociation and recombination of N2 molecules and the high thermal transport property of nitrogen gas play important roles in the increase in TPJ power density. Furthermore, we obtained TPJ extension with N2 addition that reached 300 mm, and it showed spatial enhancement of heat transport characteristics.

Space platform power system hardware testbed

NASA Technical Reports Server (NTRS)

Sable, D.; Patil, A.; Sizemore, T.; Deuty, S.; Noon, J.; Cho, B. H.; Lee, F. C.

1991-01-01

The scope of the work on the NASA Space Platform includes the design of a multi-module, multi-phase boost regulator, and a voltage-fed, push-pull autotransformer converter for the battery discharger. A buck converter was designed for the charge regulator. Also included is the associated mode control electronics for the charger and discharger, as well as continued development of a comprehensive modeling and simulation tool for the system. The design of the multi-module boost converter is discussed for use as a battery discharger. An alternative battery discharger design is discussed using a voltage-fed, push-pull autotransformer converter. The design of the charge regulator is explained using a simple buck converter. The design of the mode controller and effects of locating the bus filter capacitor bank 20 feet away from the power ORU are discussed. A brief discussion of some alternative topologies for battery charging and discharging is included. The power system modeling is described.

Boosting current generation in microbial fuel cells by an order of magnitude by coating an ionic liquid polymer on carbon anodes.

PubMed

Yang, Lu; Deng, Wenfang; Zhang, Youming; Tan, Yueming; Ma, Ming; Xie, Qingji

2017-05-15

Microbial fuel cells (MFCs) have attracted great attentions due to their great application potentials, but the relatively low power densities of MFCs still hinder their widespread practical applications. Herein, we report that the current generation in MFCs can be boosted by an order of magnitude, simply by coating a hydrophilic and positively charged ionic liquid polymer (ILP) on carbon cloth (CC) or carbon felt (CF). The ILP coating not only can increase the bacterial loading capacity due to the electrostatic interactions between ILP and bacterial cells, but also can improve the mediated extracellular electron transfer between the electrode and the cytochrome proteins on the outer membrane of Shewanella putrefaciens cells. As a result, the maximum power density of a MFC equipped with the CF-ILP bioanode is as high as 4400±170mWm -2 , which is amongst the highest values reported to date. This work demonstrates a new strategy for greatly boosting the current generation in MFCs. Copyright © 2017 Elsevier B.V. All rights reserved.

Closed Loop Fuzzy Logic Controlled PV Based Cascaded Boost Five-Level Inverter System

NASA Astrophysics Data System (ADS)

Revana, Guruswamy; Kota, Venkata Reddy

2018-04-01

Recent developments in intelligent control methods and power electronics have produced PV based DC to AC converters related to AC drives. Cascaded boost converter and inverter find their way in interconnecting PV and Induction Motor. This paper deals with digital simulation and implementation of closed loop controlled five-level inverter based Photo-Voltaic (PV) system. The objective of this work is to reduce the harmonics using Multi Level Inverter based system. The DC output from the PV panel is boosted using cascaded-boost-converters. The DC output of these cascaded boost converters is applied to the bridges of the cascaded inverter. The AC output voltage is obtained by the series cascading of the output voltage of the two inverters. The investigations are done with Induction motor load. Cascaded boost-converter is proposed in the present work to produce the required DC Voltage at the input of the bridge inverter. A simple FLC is applied to CBFLIIM system. The FLC is proposed to reduce the steady state error. The simulation results are compared with the hardware results. The results of the comparison are made to show the improvement in dynamic response in terms of settling time and steady state error. Design procedure and control strategy are presented in detail.

Closed Loop Fuzzy Logic Controlled PV Based Cascaded Boost Five-Level Inverter System

NASA Astrophysics Data System (ADS)

Revana, Guruswamy; Kota, Venkata Reddy

2017-12-01

Recent developments in intelligent control methods and power electronics have produced PV based DC to AC converters related to AC drives. Cascaded boost converter and inverter find their way in interconnecting PV and Induction Motor. This paper deals with digital simulation and implementation of closed loop controlled five-level inverter based Photo-Voltaic (PV) system. The objective of this work is to reduce the harmonics using Multi Level Inverter based system. The DC output from the PV panel is boosted using cascaded-boost-converters. The DC output of these cascaded boost converters is applied to the bridges of the cascaded inverter. The AC output voltage is obtained by the series cascading of the output voltage of the two inverters. The investigations are done with Induction motor load. Cascaded boost-converter is proposed in the present work to produce the required DC Voltage at the input of the bridge inverter. A simple FLC is applied to CBFLIIM system. The FLC is proposed to reduce the steady state error. The simulation results are compared with the hardware results. The results of the comparison are made to show the improvement in dynamic response in terms of settling time and steady state error. Design procedure and control strategy are presented in detail.

Boosting jet power in black hole spacetimes

PubMed Central

Neilsen, David; Lehner, Luis; Palenzuela, Carlos; Hirschmann, Eric W.; Liebling, Steven L.; Motl, Patrick M.; Garrett, Travis

2011-01-01

The extraction of rotational energy from a spinning black hole via the Blandford–Znajek mechanism has long been understood as an important component in models to explain energetic jets from compact astrophysical sources. Here we show more generally that the kinetic energy of the black hole, both rotational and translational, can be tapped, thereby producing even more luminous jets powered by the interaction of the black hole with its surrounding plasma. We study the resulting Poynting jet that arises from single boosted black holes and binary black hole systems. In the latter case, we find that increasing the orbital angular momenta of the system and/or the spins of the individual black holes results in an enhanced Poynting flux. PMID:21768341

Long-Term Reliability of a Hard-Switched Boost Power Processing Unit Utilizing SiC Power MOSFETs

NASA Technical Reports Server (NTRS)

Ikpe, Stanley A.; Lauenstein, Jean-Marie; Carr, Gregory A.; Hunter, Don; Ludwig, Lawrence L.; Wood, William; Iannello, Christopher J.; Del Castillo, Linda Y.; Fitzpatrick, Fred D.; Mojarradi, Mohammad M.;

Mission Analysis for LEO Microwave Power-Beaming Station in Orbital Launch of Microwave Lightcraft

NASA Technical Reports Server (NTRS)

Myrabo, L. N.; Dickenson, T.

2005-01-01

A detailed mission analysis study has been performed for a 1 km diameter, rechargeable satellite solar power station (SPS) designed to boost 20m diameter, 2400 kg Micr,oWave Lightcraft (MWLC) into low earth orbit (LEO) Positioned in a 476 km daily-repeating oi.bit, the 35 GHz microwave power station is configured like a spinning, thin-film bicycle wheel covered by 30% efficient sola cells on one side and billions of solid state microwave transmitter elements on the other, At the rim of this wheel are two superconducting magnets that can stor,e 2000 G.J of energy from the 320 MW, solar array over a period of several orbits. In preparation for launch, the entire station rotates to coarsely point at the Lightcraft, and then phases up using fine-pointing information sent from a beacon on-board the Lightcraft. Upon demand, the station transmits a 10 gigawatt microwave beam to lift the MWLC from the earth surface into LEO in a flight of several minutes duration. The mission analysis study was comprised of two parts: a) Power station assessment; and b) Analysis of MWLC dynamics during the ascent to orbit including the power-beaming relationships. The power station portion addressed eight critical issues: 1) Drag force vs. station orbital altitude; 2) Solar pressure force on the station; 3) Station orbital lifetime; 4) Feasibility of geo-magnetic re-boost; 5) Beta angle (i..e., sola1 alignment) and power station effective area relationship; 6) Power station percent time in sun vs, mission elapsed time; 7) Station beta angle vs.. charge time; 8) Stresses in station structures.. The launch dynamics portion examined four issues: 1) Ascent mission/trajecto1y profile; 2) MWLC/power-station mission geometry; 3) MWLC thrust angle vs. time; 4) Power station pitch rate during power beaming. Results indicate that approximately 0 58 N of drag force acts upon the station when rotated edge-on to project the minimum frontal area of 5000 sq m. An ion engine or perhaps an electrodynamic thruster (i.e., geomagnetic re-boost) station-keeping system can maintain the orbit altitude. The rate at which the power station s superconducting magnetic energy storage system (SMES) is 'charged' directly relates to the beta angle since the station is operating in the edge-on attitude. The maximum charge rate occurs when the beta angle is at its maximum because time in the sun and projected area of the station are, too, at their maximums For the maximum charge of 2000 G.J with a maximum beta angle of 52 degrees, approximately 3 hours (2 orbital revolutions) are required to reach the full charge, while about 16 hours (10.3 revolutions) are required when the beta angle is 10 degrees. Overall, the LEO station concept appears to be a viable candidate fo1 the formidable power-beaming infrastructure needed to boost MWLC into low earth orbit.

High-Dose Split-Course Radiation Therapy for Anal Cancer: Outcome Analysis Regarding the Boost Strategy (CORS-03 Study)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hannoun-Levi, Jean-Michel, E-mail: jean-michel.hannoun-levi@nice.fnclcc.fr; Cercle des Oncologues Radiotherapeutes du Sud; Ortholan, Cecile

2011-07-01

Purpose: To retrospectively assess the clinical outcome in anal cancer patients treated with split-course radiation therapy and boosted through external-beam radiation therapy (EBRT) or brachytherapy (BCT). Methods and Materials: From January 2000 to December 2004, a selected group (162 patients) with invasive nonmetastatic anal squamous cell carcinoma was studied. Tumor staging reported was T1 = 31 patients (19%), T2 = 77 patients (48%), T3 = 42 patients (26%), and T4= 12 patients (7%). Lymph node status was N0-1 (86%) and N2-3 (14%). Patients underwent a first course of EBRT: mean dose 45.1 Gy (range, 39.5-50) followed by a boost: meanmore » dose 17.9 Gy (range, 8-25) using EBRT (76 patients, 47%) or BCT (86 patients, 53%). All characteristics of patients and tumors were well balanced between the BCT and EBRT groups. Results: The mean overall treatment time (OTT) was 82 days (range, 45-143) and 67 days (range, 37-128) for the EBRT and BCT groups, respectively (p < 0.001). The median follow-up was 62 months (range, 2-108). The 5-year cumulative rate of local recurrence (CRLR) was 21%. In the univariate analysis, the prognostic factors for CRLR were as follows: T stage (T1-2 = 15% vs. T3-4 = 36%, p = 0.03), boost technique (BCT = 12% vs. EBRT = 33%, p = 0.002) and OTT (OTT <80 days = 14%, OTT {>=}80 days = 34%, p = 0.005). In the multivariate analysis, BCT boost was the unique prognostic factor (hazard ratio = 0.62 (0.41-0.92). In the subgroup of patients with OTT <80 days, the 5-year CRLR was significantly increased with the BCT boost (BC = 9% vs. EBRT = 28%, p = 0.03). In the case of OTT {>=}80 days, the 5-year CRLR was not affected by the boost technique (BCT = 29% vs. EBRT = 38%, p = 0.21). Conclusion: In anal cancer, when OTT is <80 days, BCT boost is superior to EBRT boost for CRLR. These results suggest investigating the benefit of BCT boost in prospective trials.« less

A 540-[Formula: see text] Duty Controlled RSSI With Current Reusing Technique for Human Body Communication.

PubMed

Jang, Jaeeun; Lee, Yongsu; Cho, Hyunwoo; Yoo, Hoi-Jun

2016-08-01

An ultra-low-power duty controlled received signal strength indicator (RSSI) is implemented for human body communication (HBC) in 180 nm CMOS technology under 1.5 V supply. The proposed RSSI adopted 3 following key features for low-power consumption; 1) current reusing technique (CR-RSSI) with replica bias circuit and calibration unit, 2) duty controller, and 3) reconfigurable gm-boosting LNA. The CR-RSSI utilizes stacked amplifier-rectifier-cell (AR-cell) to reuse the supply current of each blocks. As a result, the power consumption becomes 540 [Formula: see text] with +/-2 dB accuracy and 75 dB dynamic range. The replica bias circuit and calibration unit are adopted to increase the reliability of CR-RSSI. In addition, the duty controller turns off the RSSI when it is not required, and this function leads 70% power reduction. At last, the gm-boosting reconfigurable LNA can adaptively vary its noise and linearity performance with respect to input signal strength. Fro current reusing technique m this feature, we achieve 62% power reduction in the LNA. Thanks to these schemes, compared to the previous works, we can save 70% of power in RSSI and LNA.

Series-Connected Buck Boost Regulators

NASA Technical Reports Server (NTRS)

Birchenough, Arthur G.

2005-01-01

A series-connected buck boost regulator (SCBBR) is an electronic circuit that bucks a power-supply voltage to a lower regulated value or boosts it to a higher regulated value. The concept of the SCBBR is a generalization of the concept of the SCBR, which was reported in "Series-Connected Boost Regulators" (LEW-15918), NASA Tech Briefs, Vol. 23, No. 7 (July 1997), page 42. Relative to prior DC-voltage-regulator concepts, the SCBBR concept can yield significant reductions in weight and increases in power-conversion efficiency in many applications in which input/output voltage ratios are relatively small and isolation is not required, as solar-array regulation or battery charging with DC-bus regulation. Usually, a DC voltage regulator is designed to include a DC-to-DC converter to reduce its power loss, size, and weight. Advances in components, increases in operating frequencies, and improved circuit topologies have led to continual increases in efficiency and/or decreases in the sizes and weights of DC voltage regulators. The primary source of inefficiency in the DC-to-DC converter portion of a voltage regulator is the conduction loss and, especially at high frequencies, the switching loss. Although improved components and topology can reduce the switching loss, the reduction is limited by the fact that the converter generally switches all the power being regulated. Like the SCBR concept, the SCBBR concept involves a circuit configuration in which only a fraction of the power is switched, so that the switching loss is reduced by an amount that is largely independent of the specific components and circuit topology used. In an SCBBR, the amount of power switched by the DC-to-DC converter is only the amount needed to make up the difference between the input and output bus voltage. The remaining majority of the power passes through the converter without being switched. The weight and power loss of a DC-to-DC converter are determined primarily by the amount of power processed. In the SCBBR, the unswitched majority of the power is passed through with very little power loss, and little if any increase in the sizes of the converter components is needed to enable the components to handle the unswitched power. As a result, the power-conversion efficiency of the regulator can be very high, as shown in the example of Figure 1. A basic SCBBR includes a DC-to-DC converter (see Figure 2). The switches and primary winding of a transformer in the converter is connected across the input bus, while the secondary winding and switches are connected in series with the output bus, so that the output voltage is the sum of the input voltage and the secondary voltage of the converter. In the breadboard SCBBR, the input voltage applied to the primary winding is switched by use of metal oxide/semiconductor field-effect transistors (MOSFETs) in a full bridge circuit; the secondary winding is center-tapped, with two MOSFET switches and diode rectifiers connected in opposed series in each leg. The sets of opposed switches and rectifiers are what enable operation in either a boost or a buck mode. In the boost mode, input voltage and current, and the output voltage and current are all positive; that is, the secondary voltage is added to the input voltage and the net output voltage can be regulated at a value equal or greater than the input voltage. In the buck mode, input voltage is still positive and the current still flows in the same direction in the secondary, but the switches are controlled such that some power flows from the secondary to the primary. The voltage across the secondary and the current into the primary are reversed. The result is that the output voltage is lower than the input voltage, and some power is recirculated from the converter secondary back to the input. Quantitatively, the advantage of an SCBBR is a direct function of the regulation range required. If, for example, a regulation range of 20 percent is required for a 500-W supply, th it suffices to design the DC-to-DC converter in the SCBBR for a power rating of only 100 W. The switching loss and size are much smaller than those of a conventional regulator that must be rated for switching of all 500 W. The reduction in size and the increase in efficiency are not directly proportional to switched-power ratio of 5:1 because the additional switches contribute some conduction loss and the input and output filters must be larger than those typically required for a 100-W converter. Nevertheless, the power loss and the size can be much smaller than those of a 500-W converter.

Apparatus and method for compensating for electron beam emittance in synchronizing light sources

DOEpatents

Neil, George R.

1996-01-01

A focused optical beam is used to change the path length of the core electrons in electron light sources thereby boosting their efficiency of conversion of electron beam energy to light. Both coherent light in the free electron laser and incoherent light in the synchrotron is boosted by this technique. By changing the path length of the core electrons by the proper amount, the core electrons are caused to stay in phase with the electrons in the outer distribution of the electron beam. This increases the fraction of the electron beam energy that is converted to light thereby improving the efficiency of conversion of energy to light and therefore boosting the power output of the free electron laser and synchrotron.

Apparatus and method for compensating for electron beam emittance in synchronizing light sources

DOEpatents

Neil, G.R.

1996-07-30

A focused optical beam is used to change the path length of the core electrons in electron light sources thereby boosting their efficiency of conversion of electron beam energy to light. Both coherent light in the free electron laser and incoherent light in the synchrotron is boosted by this technique. By changing the path length of the core electrons by the proper amount, the core electrons are caused to stay in phase with the electrons in the outer distribution of the electron beam. This increases the fraction of the electron beam energy that is converted to light thereby improving the efficiency of conversion of energy to light and therefore boosting the power output of the free electron laser and synchrotron. 4 figs.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Clark, Hamish A.; Iwanus, Nikolas; Lewis, Geraint F.

The existence of substructure in halos of annihilating dark matter would be expected to substantially boost the rate at which annihilation occurs. Ultracompact minihalos of dark matter (UCMHs) are one of the more extreme examples of this. The boosted annihilation can inject significant amounts of energy into the gas of a galaxy over its lifetime. Here we determine the impact of the boost factor from UCMH substructure on the heating of galactic gas in a Milky Way-type galaxy, by means of N-body simulation. If 1% of the dark matter exists as UCMHs, the corresponding boost factor can be of ordermore » 10{sup 5}. For reasonable values of the relevant parameters (annihilation cross section 3×10{sup −26} cm{sup 3} s{sup −1}, dark matter mass 100 GeV, 10% heating efficiency), we show that the presence of UCMHs at the 0.1% level would inject enough energy to eject significant amounts of gas from the halo, potentially preventing star formation within ∼1 kpc of the halo centre.« less

Predictive GT-Power Simulation for VNT Matching on a 1.6 L Turbocharged GDI Engine

EPA Science Inventory

The thermal efficiency benefits of low-pressure (LP) exhaust gas recirculation (EGR) in spark-ignition engine combustion are well known. One of the greatest barriers facing adoption of LP-EGR for high power-density applications is the challenge of boosting. Variable nozzle turbin...

Start Smart! Building Brain Power in the Early Years.

ERIC Educational Resources Information Center

Schiller, Pam

Noting current brain development research, this book offers simple, straightforward ways to boost children's brain power with active exploration, repetition, sensory exploration, laughter, and more. The chapters describe how and why the brain develops and explain how parents can give their children the best foundation for future learning.…

A methodology for boost-glide transport technology planning

NASA Technical Reports Server (NTRS)

Repic, E. M.; Olson, G. A.; Milliken, R. J.

1974-01-01

A systematic procedure is presented by which the relative economic value of technology factors affecting design, configuration, and operation of boost-glide transport can be evaluated. Use of the methodology results in identification of first-order economic gains potentially achievable by projected advances in each of the definable, hypersonic technologies. Starting with a baseline vehicle, the formulas, procedures and forms which are integral parts of this methodology are developed. A demonstration of the methodology is presented for one specific boost-glide system.

Enhanced power generation in concentrated photovoltaics using broadband antireflective coverglasses with moth eye structures.

PubMed

Song, Young Min; Jeong, Yonkil; Yeo, Chan Il; Lee, Yong Tak

2012-11-05

We present the effect of broadband antireflective coverglasses (BARCs) with moth eye structures on the power generation capability of a sub-receiver module for concentrated photovoltaics. The period and height of the moth eye structures were designed by a rigorous coupled-wave analysis method in order to cover the full solar spectral ranges without transmission band shrinkage. The BARCs with moth eye structures were prepared by the dry etching of silver (Ag) nanomasks, and the fabricated moth eye structures on coverglass showed strongly enhanced transmittance compared to the bare glass with a flat surface, at wavelengths of 300 - 1800 nm. The BARCs were mounted on InGaP/GaAs/Ge triple-junction solar cells and the power conversion efficiency of this sub-receiver module reached 42.16% for 196 suns, which is a 7.41% boosted value compared to that of a module with bare coverglass, without any detrimental changes of the open circuit voltages (V_oc) and fill factor (FF).

Enhanced power generation in concentrated photovoltaics using broadband antireflective coverglasses with moth eye structures.

PubMed

Song, Young Min; Jeong, Yonkil; Yeo, Chan Il; Lee, Yong Tak

2012-11-05

We present the effect of broadband antireflective coverglasses (BARCs) with moth eye structures on the power generation capability of a sub-receiver module for concentrated photovoltaics. The period and height of the moth eye structures were designed by a rigorous coupled-wave analysis method in order to cover the full solar spectral ranges without transmission band shrinkage. The BARCs with moth eye structures were prepared by the dry etching of silver (Ag) nanomasks, and the fabricated moth eye structures on coverglass showed strongly enhanced transmittance compared to the bare glass with a flat surface, at wavelengths of 300 - 1800 nm. The BARCs were mounted on InGaP/GaAs/Ge triple-junction solar cells and the power conversion efficiency of this sub-receiver module reached 42.16% for 196 suns, which is a 7.41% boosted value compared to that of a module with bare coverglass, without any detrimental changes of the open circuit voltages (V(oc)) and fill factor (FF).

A CMOS image sensor with programmable pixel-level analog processing.

PubMed

Massari, Nicola; Gottardi, Massimo; Gonzo, Lorenzo; Stoppa, David; Simoni, Andrea

2005-11-01

A prototype of a 34 x 34 pixel image sensor, implementing real-time analog image processing, is presented. Edge detection, motion detection, image amplification, and dynamic-range boosting are executed at pixel level by means of a highly interconnected pixel architecture based on the absolute value of the difference among neighbor pixels. The analog operations are performed over a kernel of 3 x 3 pixels. The square pixel, consisting of 30 transistors, has a pitch of 35 microm with a fill-factor of 20%. The chip was fabricated in a 0.35 microm CMOS technology, and its power consumption is 6 mW with 3.3 V power supply. The device was fully characterized and achieves a dynamic range of 50 dB with a light power density of 150 nW/mm2 and a frame rate of 30 frame/s. The measured fixed pattern noise corresponds to 1.1% of the saturation level. The sensor's dynamic range can be extended up to 96 dB using the double-sampling technique.

Technical Study of a Standalone Photovoltaic–Wind Energy Based Hybrid Power Supply Systems for Island Electrification in Malaysia

PubMed Central

Samrat, Nahidul Hoque; Ahmad, Norhafizan; Choudhury, Imtiaz Ahmed; Taha, Zahari

2015-01-01

Energy is one of the most important factors in the socioeconomic development of a country. In a developing country like Malaysia, the development of islands is mostly related to the availability of electric power. Power generated by renewable energy sources has recently become one of the most promising solutions for the electrification of islands and remote rural areas. But high dependency on weather conditions and the unpredictable nature of these renewable energy sources are the main drawbacks. To overcome this weakness, different green energy sources and power electronic converters need to be integrated with each other. This study presents a battery storage hybrid standalone photovoltaic-wind energy power supply system. In the proposed standalone hybrid system, a DC-DC buck-boost bidirectional converter controller is used to accumulates the surplus hybrid power in the battery bank and supplies this power to the load during the hybrid power shortage by maintaining the constant dc-link voltage. A three-phase voltage source inverter complex vector control scheme is used to control the load side voltage in terms of the voltage amplitude and frequency. Based on the simulation results obtained from MATLAB/Simulink, it has been found that the overall hybrid framework is capable of working under variable weather and load conditions. PMID:26121032

Technical Study of a Standalone Photovoltaic-Wind Energy Based Hybrid Power Supply Systems for Island Electrification in Malaysia.

PubMed

Samrat, Nahidul Hoque; Ahmad, Norhafizan; Choudhury, Imtiaz Ahmed; Taha, Zahari

2015-01-01

Energy is one of the most important factors in the socioeconomic development of a country. In a developing country like Malaysia, the development of islands is mostly related to the availability of electric power. Power generated by renewable energy sources has recently become one of the most promising solutions for the electrification of islands and remote rural areas. But high dependency on weather conditions and the unpredictable nature of these renewable energy sources are the main drawbacks. To overcome this weakness, different green energy sources and power electronic converters need to be integrated with each other. This study presents a battery storage hybrid standalone photovoltaic-wind energy power supply system. In the proposed standalone hybrid system, a DC-DC buck-boost bidirectional converter controller is used to accumulates the surplus hybrid power in the battery bank and supplies this power to the load during the hybrid power shortage by maintaining the constant dc-link voltage. A three-phase voltage source inverter complex vector control scheme is used to control the load side voltage in terms of the voltage amplitude and frequency. Based on the simulation results obtained from MATLAB/Simulink, it has been found that the overall hybrid framework is capable of working under variable weather and load conditions.

Optimal Design of a Resonance-Based Voltage Boosting Rectifier for Wireless Power Transmission.

PubMed

Lim, Jaemyung; Lee, Byunghun; Ghovanloo, Maysam

2018-02-01

This paper presents the design procedure for a new multi-cycle resonance-based voltage boosting rectifier (MCRR) capable of delivering a desired amount of power to the load (PDL) at a designated high voltage (HV) through a loosely-coupled inductive link. This is achieved by shorting the receiver (Rx) LC-tank for several cycles to harvest and accumulate the wireless energy in the RX inductor before boosting the voltage by breaking the loop and transferring the energy to the load in a quarter cycle. By optimizing the geometries of the transmitter (Tx) and Rx coils and the number of cycles, N , for energy harvesting, through an iterative design procedure, the MCRR can achieve the highest PDL under a given set of design constraints. Governing equations in the MCRR operation are derived to identify key specifications and the design guidelines. Using an exemplary set of specs, the optimized MCRR was able to generate 20.9 V DC across a 100 kΩ load from a 1.8 V p , 6.78 MHz sinusoid input in the ISM-band at a Tx/Rx coil separation of 1.3 cm, power transfer efficiency (PTE) of 2.2%, and N = 9 cycles. At the same coil distance and loading, coils optimized for a conventional half-wave rectifier (CHWR) were able to reach only 13.6 V DC from the same source.

An evaluation of a hubless inducer and a full flow hydraulic turbine driven inducer boost pump

NASA Technical Reports Server (NTRS)

Lindley, B. K.; Martinson, A. R.

1971-01-01

The purpose of the study was to compare the performance of several configurations of hubless inducers with a hydrodynamically similar conventional inducer and to demonstrate the performance of a full flow hydraulic turbine driven inducer boost pump using these inducers. A boost pump of this type consists of an inducer connected to a hydraulic turbine with a high speed rotor located in between. All the flow passes through the inducer, rotor, and hydraulic turbine, then into the main pump. The rotor, which is attached to the main pump shaft, provides the input power to drive the hydraulic turbine which, in turn, drives the inducer. The inducer, rotating at a lower speed, develops the necessary head to prevent rotor cavitation. The rotor speed is consistent with present main engine liquid hydrogen pump designs and the overall boost pump head rise is sufficient to provide adequate main pump suction head. This system would have the potential for operating at lower liquid hydrogen tank pressures.

Application handbook for a Standardized Control Module (SCM) for DC-DC converters, volume 1

NASA Astrophysics Data System (ADS)

Lee, F. C.; Mahmoud, M. F.; Yu, Y.

1980-04-01

The standardized control module (SCM) was developed for application in the buck, boost and buck/boost DC-DC converters. The SCM used multiple feedback loops to provide improved input line and output load regulation, stable feedback control system, good dynamic transient response and adaptive compensation of the control loop for changes in open loop gain and output filter time constraints. The necessary modeling and analysis tools to aid the design engineer in the application of the SCM to DC-DC Converters were developed. The SCM functional block diagram and the different analysis techniques were examined. The average time domain analysis technique was chosen as the basic analytical tool. The power stage transfer functions were developed for the buck, boost and buck/boost converters. The analog signal and digital signal processor transfer functions were developed for the three DC-DC Converter types using the constant on time, constant off time and constant frequency control laws.

Application handbook for a Standardized Control Module (SCM) for DC-DC converters, volume 1

NASA Technical Reports Server (NTRS)

Lee, F. C.; Mahmoud, M. F.; Yu, Y.

1980-01-01

The standardized control module (SCM) was developed for application in the buck, boost and buck/boost DC-DC converters. The SCM used multiple feedback loops to provide improved input line and output load regulation, stable feedback control system, good dynamic transient response and adaptive compensation of the control loop for changes in open loop gain and output filter time constraints. The necessary modeling and analysis tools to aid the design engineer in the application of the SCM to DC-DC Converters were developed. The SCM functional block diagram and the different analysis techniques were examined. The average time domain analysis technique was chosen as the basic analytical tool. The power stage transfer functions were developed for the buck, boost and buck/boost converters. The analog signal and digital signal processor transfer functions were developed for the three DC-DC Converter types using the constant on time, constant off time and constant frequency control laws.

Simulation comparison of proportional integral derivative and fuzzy logic in controlling AC-DC buck boost converter

NASA Astrophysics Data System (ADS)

Faisal, A.; Hasan, S.; Suherman

2018-03-01

AC-DC converter is widely used in the commercial industry even for daily purposes. The AC-DC converter is used to convert AC voltage into DC. In order to obtain the desired output voltage, the converter usually has a controllable regulator. This paper discusses buck boost regulator with a power MOSFET as switching component which is adjusted based on the duty cycle of pulse width modulation (PWM). The main problems of the buck boost converter at start up are the high overshoot, the long peak time and rise time. This paper compares the effectiveness of two control techniques: proportional integral derivative (PID) and fuzzy logic control in controlling the buck boost converter through simulations. The results show that the PID is more sensitive to voltage change than fuzzy logic. However, PID generates higher overshoot, long peak time and rise time. On the other hand, fuzzy logic generates no overshoot and shorter rise time.

Replica Exchange Gaussian Accelerated Molecular Dynamics: Improved Enhanced Sampling and Free Energy Calculation.

PubMed

Huang, Yu-Ming M; McCammon, J Andrew; Miao, Yinglong

2018-04-10

Through adding a harmonic boost potential to smooth the system potential energy surface, Gaussian accelerated molecular dynamics (GaMD) provides enhanced sampling and free energy calculation of biomolecules without the need of predefined reaction coordinates. This work continues to improve the acceleration power and energy reweighting of the GaMD by combining the GaMD with replica exchange algorithms. Two versions of replica exchange GaMD (rex-GaMD) are presented: force constant rex-GaMD and threshold energy rex-GaMD. During simulations of force constant rex-GaMD, the boost potential can be exchanged between replicas of different harmonic force constants with fixed threshold energy. However, the algorithm of threshold energy rex-GaMD tends to switch the threshold energy between lower and upper bounds for generating different levels of boost potential. Testing simulations on three model systems, including the alanine dipeptide, chignolin, and HIV protease, demonstrate that through continuous exchanges of the boost potential, the rex-GaMD simulations not only enhance the conformational transitions of the systems but also narrow down the distribution width of the applied boost potential for accurate energetic reweighting to recover biomolecular free energy profiles.

An optimal design of magnetostrictive material (MsM) based energy harvester

NASA Astrophysics Data System (ADS)

Hu, Jingzhen; Yuan, Fuh-Gwo; Xu, Fujun; Huang, Alex Q.

2010-04-01

In this study, an optimal vibration-based energy harvesting system using magnetostrictive material (MsM) has been designed to power the Wireless Intelligent Sensor Platform (WISP), developed at North Carolina State University. A linear MsM energy harvesting device has been modeled and optimized to maximize the power output. The effects of number of MsM layers and glue layers, and load matching on the output power of the MsM energy harvester have been analyzed. From the measurement, the open circuit voltage can reach 1.5 V when the MsM cantilever beam operates at the 2nd natural frequency 324 Hz. The AC output power is 0.97 mW, giving power density 279 μW/cm3. Since the MsM device has low open circuit output voltage characteristics, a full-wave quadrupler has been designed to boost the rectified output voltage. To deliver the maximum output power to the load, a complex conjugate impedance matching between the load and the MsM device has been implemented using a discontinuous conduction mode (DCM) buck-boost converter. The maximum output power after the voltage quadrupler is now 705 μW and power density reduces to 202.4 μW/cm3, which is comparable to the piezoelectric energy harvesters given in the literature. The output power delivered to a lithium rechargeable battery is around 630 μW, independent of the load resistance.

[Design and optimization of wireless power and data transmission for visual prosthesis].

PubMed

Lei, Xuping; Wu, Kaijie; Zhao, Lei; Chai, Xinyu

2013-11-01

Boosting spatial resolution of visual prostheses is an effective method to improve implant subjects' visual perception. However, power consumption of visual implants greatly rises with the increasing number of implanted electrodes. In respond to this trend, visual prostheses need to develop high-efficiency wireless power transmission and high-speed data transmission. This paper presents a review of current research progress on wireless power and data transmission for visual prostheses, analyzes relative principles and requirement, and introduces design methods of power and data transmission.

Enhanced charging kinetics of porous electrodes: surface conduction as a short-circuit mechanism.

PubMed

Mirzadeh, Mohammad; Gibou, Frederic; Squires, Todd M

2014-08-29

We use direct numerical simulations of the Poisson-Nernst-Planck equations to study the charging kinetics of porous electrodes and to evaluate the predictive capabilities of effective circuit models, both linear and nonlinear. The classic transmission line theory of de Levie holds for general electrode morphologies, but only at low applied potentials. Charging dynamics are slowed appreciably at high potentials, yet not as significantly as predicted by the nonlinear transmission line model of Biesheuvel and Bazant. We identify surface conduction as a mechanism which can effectively "short circuit" the high-resistance electrolyte in the bulk of the pores, thus accelerating the charging dynamics and boosting power densities. Notably, the boost in power density holds only for electrode morphologies with continuous conducting surfaces in the charging direction.

Comparison between a classical command law and a new advanced recovery command law in a MCB-ARS boost

NASA Astrophysics Data System (ADS)

Petit, Pierre; Saint-Eve, Frédéric; Sawicki, Jean-Paul; Aillerie, Michel

2017-02-01

This paper focuses on an original performed command on DC-DC boosts developed for applications in the LMOPS lab for the photovoltaic energy conversion and more specifically the Photovoltaic panels connected to HVDC smart grids. This boost, commonly named MCB-ARS (Magnetically Coupled Boost with Active Recovery Switch) presents great advantages concerning the simplicity of the command on the single constitutive switch, the global efficiency and the voltage conversion ratio. A fine analysis of the losses all over the entire converter shows that losses are not distributed uniformly in the constituting components. So a previous modification described in a previous paper consisting in the conducting assistance on the power flowing intermediate diode, performed advantageously the global efficiency. The present analysis takes into account the fact that the new configuration obtained after this important improvement looks like a classical half-bridge push-pull stage and may be controlled by a twice complementary command. In that way, a comparison has been done between a natural commutation recovery diode and an assisted switch commutation driven in a push-pull mode. As attempted, the switching command laws in charge to assume the energy transfer has been compared to the classical previous system described in anterior papers, and we demonstrate in this publication that a commutation based on a push-pull command mode within the two switches of the MCB-ARS converter is possible and increases the power transfer.

NREL Joins Initiative to Boost Power Electronics Energy Efficiency and Job

Science.gov Websites

Electronics and Electric Machines team, which focuses on vehicle component research and development (R&D current silicon-based components in the next five years. The institute will bring partners together to power electronics thermal management and reliability R&D, NREL's research in this area focuses on

A Standalone Solar Photovoltaic Power Generation using Cuk Converter and Single Phase Inverter

NASA Astrophysics Data System (ADS)

Verma, A. K.; Singh, B.; Kaushika, S. C.

2013-03-01

In this paper, a standalone solar photovoltaic (SPV) power generating system is designed and modeled using a Cuk dc-dc converter and a single phase voltage source inverter (VSI). In this system, a dc-dc boost converter boosts a low voltage of a PV array to charge a battery at 24 V using a maximum power point tracking control algorithm. To step up a 24 V battery voltage to 360 V dc, a high frequency transformer based isolated dc-dc Cuk converter is used to reduce size, weight and losses. The dc voltage of 360 V is fed to a single phase VSI with unipolar switching to achieve a 230 Vrms, 50 Hz ac. The main objectives of this investigation are on efficiency improvement, reduction in cost, weight and size of the system and to provide an uninterruptible power to remotely located consumers. The complete SPV system is designed and it is modeled in MATLAB/Simulink. The simulated results are presented to demonstrate its satisfactory performance for validating the proposed design and control algorithm.

Risk factors for pre-term birth in a Canadian cohort of HIV-positive women: role of ritonavir boosting?

PubMed Central

Kakkar, Fatima; Boucoiran, Isabelle; Lamarre, Valerie; Ducruet, Thierry; Amre, Devendra; Soudeyns, Hugo; Lapointe, Normand; Boucher, Marc

2015-01-01

Background The risk of pre-term birth (PTB) associated with the use of protease inhibitors (PIs) during pregnancy remains a subject of debate. Recent data suggest that ritonavir boosting of PIs may play a specific role in the initiation of PTB, through an effect on the maternal–fetal adrenal axis. The primary objective of this study is to compare the risk of PTB among women treated with boosted PI versus non-boosted PIs during pregnancy. Methods Between 1988 and 2011, 705 HIV-positive women were enrolled into the Centre Maternel et Infantile sur le SIDA mother–infant cohort at Centre Hospitalier Universitaire Sainte-Justine in Montreal, Canada. Inclusion criteria for the study were: 1) attendance at a minimum of two antenatal obstetric visits and 2) singleton live birth, at 24 weeks gestational or older. The association between PTB (defined as delivery at <37 weeks gestational age), antiretroviral drug exposure and maternal risk factors was assessed retrospectively using logistic regression. Results A total of 525 mother–infant pairs were included in the analysis. Among them, PI-based combination anti-retroviral therapy was used in 37.4%, boosted PI based in 24.4%, non-nucleoside reverse transcriptase inhibitor (NNRTI) or nucleoside reverse transcriptase inhibitor based in 28.1%, and no treatment was given in 10.0% of cases. Overall, 13.5% of women experienced PTB. Among women treated with antiretroviral therapy, the risk of PTB was significantly higher among women who received boosted versus non-boosted PI (OR 2.01, 95% CI 1.02–3.97). This remained significant after adjusting for maternal age, delivery CD4 count, hepatitis C co-infection, history of previous PTB, and parity (aOR 2.17, 95% CI 1.05–4.51). There was no increased risk of PTB with the use of unboosted PIs as compared to NNRTI- or NRTI-based regimens. Conclusion While previous studies on the association between PTB and PI use have generally considered all PIs the same, our results would indicate a possible role of ritonavir boosting as a risk factor for PTB. Further work is needed to understand the pathophysiologic mechanisms involved, and to identify the safest ARV regimens to be used in pregnancy. PMID:26051165

Design and optimization of ARC less InGaP/GaAs single-/multi-junction solar cells with tunnel junction and back surface field layers

NASA Astrophysics Data System (ADS)

Chee, Kuan W. A.; Hu, Yuning

2018-07-01

There has always been an inexorable interest in the solar industry in boosting the photovoltaic conversion efficiency. This paper presents a theoretical and numerical simulation study of the effects of key design parameters on the photoelectric performance of single junction (InGaP- or GaAs-based) and dual junction (InGaP/GaAs) inorganic solar cells. The influence of base layer thickness, base doping concentration, junction temperature, back surface field layer composition and thickness, and tunnel junction material, were correlated with open circuit voltage, short-circuit current, fill factor and power conversion efficiency performance. The InGaP/GaAs dual junction solar cell was optimized with the tunnel junction and back surface field designs, yielding a short-circuit current density of 20.71 mAcm-2 , open-circuit voltage of 2.44 V and fill factor of 88.6%, and guaranteeing an optimal power conversion efficiency of at least 32.4% under 1 sun AM0 illumination even without an anti-reflective coating.

A digital prediction algorithm for a single-phase boost PFC

NASA Astrophysics Data System (ADS)

Qing, Wang; Ning, Chen; Weifeng, Sun; Shengli, Lu; Longxing, Shi

2012-12-01

A novel digital control algorithm for digital control power factor correction is presented, which is called the prediction algorithm and has a feature of a higher PF (power factor) with lower total harmonic distortion, and a faster dynamic response with the change of the input voltage or load current. For a certain system, based on the current system state parameters, the prediction algorithm can estimate the track of the output voltage and the inductor current at the next switching cycle and get a set of optimized control sequences to perfectly track the trajectory of input voltage. The proposed prediction algorithm is verified at different conditions, and computer simulation and experimental results under multi-situations confirm the effectiveness of the prediction algorithm. Under the circumstances that the input voltage is in the range of 90-265 V and the load current in the range of 20%-100%, the PF value is larger than 0.998. The startup and the recovery times respectively are about 0.1 s and 0.02 s without overshoot. The experimental results also verify the validity of the proposed method.

[Satisfaction with life of children with attention deficit hyperactivity disorder: a study of possible protection and risk factors].

PubMed

Miranda-Casas, Ana; Presentacion-Herrero, M Jesús; Colomer-Diago, Carla; Roselló, Belén

2011-03-01

Positive psychology has boosted interest about the study of factors of adjustment, among which is included satisfaction with life. To analyze the relationship between satisfaction with life of children with attention deficit hyperactivity disorder (ADHD) and their parents with behavioral risk and protective variables, and to determine the predictive power of these variables. 56 parents and their children with ADHD filled out questionnaires of satisfaction with life, self-concept, sense of coherence, success attributes and behavioral rating scales. Behavioral problems have a significant negative relationship with satisfaction with life perceived by parents and by children while the relationships with the self-concept and success attributes have a positive value. The most predictive factors were social problems, oppositional behavior, self-concept, self-awareness and social support. The identification of factors that put at risk or enhance satisfaction with life of people with ADHD will improve the functionality of evaluation and intervention processes.

The Series Connected Buck Boost Regulator Concept for High Efficiency Light Weight DC Voltage Regulation

NASA Technical Reports Server (NTRS)

Birchenough, Arthur G.

2003-01-01

Improvements in the efficiency and size of DC-DC converters have resulted from advances in components, primarily semiconductors, and improved topologies. One topology, which has shown very high potential in limited applications, is the Series Connected Boost Unit (SCBU), wherein a small DC-DC converter output is connected in series with the input bus to provide an output voltage equal to or greater than the input voltage. Since the DC-DC converter switches only a fraction of the power throughput, the overall system efficiency is very high. But this technique is limited to applications where the output is always greater than the input. The Series Connected Buck Boost Regulator (SCBBR) concept extends partial power processing technique used in the SCBU to operation when the desired output voltage is higher or lower than the input voltage, and the implementation described can even operate as a conventional buck converter to operate at very low output to input voltage ratios. This paper describes the operation and performance of an SCBBR configured as a bus voltage regulator providing 50 percent voltage regulation range, bus switching, and overload limiting, operating above 98 percent efficiency. The technique does not provide input-output isolation.

Uncovering potential “herbal probiotics” in Juzen-taiho-to through the study of associated bacterial populations

PubMed Central

Montenegro, Diego; Kalpana, Kriti; Chrissian, Christine; Sharma, Ashutosh; Takaoka, Anna; Iacovidou, Maria; Soll, Clifford E.; Aminova, Olga; Heguy, Adriana; Cohen, Lisa; Shen, Steven

2014-01-01

Juzen-taiho-to (JTT) is an immune-boosting formulation of ten medicinal herbs. It is used clinically in East Asia to boost the human immune functions. The active factors in JTT have not been clarified. But, existing evidence suggests that lipopolysaccharide (LPS)-like factors contribute to the activity. To examine this possibility, JTT was subjected to a series of analyses, including high resolution mass spectrometry, which suggested the presence of structural variants of LPS. This finding opened a possibility that JTT contains immune-boosting bacteria. As the first step to characterize the bacteria in JTT, 16S ribosomal RNA sequencing was carried out for Angelica sinensis (dried root), one of the most potent immunostimulatory herbs in JTT. The sequencing revealed a total of 519 bacteria genera in A. sinensis. The most abundant genus was Rahnella, which is widely distributed in water and plants. The abundance of Rahnella appeared to correlate with the immunostimulatory activity of A. sinensis. In conclusion, the current study provided new pieces of evidence supporting the emerging theory of bacterial contribution in immune-boosting herbs. PMID:25547935

R&D100: 6.5kV Enhancement-Mode Silicon Carbide JFET Switch

ScienceCinema

Dries, Chris; Hostetler, John; Atcitty, Stan

2018-06-12

Researchers at Sandia National Laboratories have partnered with United Silicon Carbide, Inc. to combine advanced materials with novel manufacturing ideas to build a new product for significantly more efficient power conversion. Harnessing the unique features of silicon carbide, this first of its kind device allows higher voltage switching, and reductions in switching losses to significantly boost the efficiency and reliability of power generation and power conversion.

Efficiency Enhancement of a Cantilever-Based Vibration Energy Harvester

PubMed Central

Kubba, Ali E.; Jiang, Kyle

2014-01-01

Extracting energy from ambient vibration to power wireless sensor nodes has been an attractive area of research, particularly in the automotive monitoring field. This article reports the design, analysis and testing of a vibration energy harvesting device based on a miniature asymmetric air-spaced cantilever. The developed design offers high power density, and delivers electric power that is sufficient to support most wireless sensor nodes for structural health monitoring (SHM) applications. The optimized design underwent three evolutionary steps, starting from a simple cantilever design, going through an air-spaced cantilever, and ending up with an optimized air-spaced geometry with boosted power density level. Finite Element Analysis (FEA) was used as an initial tool to compare the three geometries' stiffness (K), output open-circuit voltage (Vave), and average normal strain in the piezoelectric transducer (εave) that directly affect its output voltage. Experimental tests were also carried out in order to examine the energy harvesting level in each of the three designs. The experimental results show how to boost the power output level in a thin air-spaced cantilever beam for energy within the same space envelope. The developed thin air-spaced cantilever (8.37 cm3), has a maximum power output of 2.05 mW (H = 29.29 μJ/cycle). PMID:24366177

Efficiency enhancement of a cantilever-based vibration energy harvester.

PubMed

Kubba, Ali E; Jiang, Kyle

2013-12-23

Extracting energy from ambient vibration to power wireless sensor nodes has been an attractive area of research, particularly in the automotive monitoring field. This article reports the design, analysis and testing of a vibration energy harvesting device based on a miniature asymmetric air-spaced cantilever. The developed design offers high power density, and delivers electric power that is sufficient to support most wireless sensor nodes for structural health monitoring (SHM) applications. The optimized design underwent three evolutionary steps, starting from a simple cantilever design, going through an air-spaced cantilever, and ending up with an optimized air-spaced geometry with boosted power density level. Finite Element Analysis (FEA) was used as an initial tool to compare the three geometries' stiffness (K), output open-circuit voltage (V(ave)), and average normal strain in the piezoelectric transducer (ε(ave)) that directly affect its output voltage. Experimental tests were also carried out in order to examine the energy harvesting level in each of the three designs. The experimental results show how to boost the power output level in a thin air-spaced cantilever beam for energy within the same space envelope. The developed thin air-spaced cantilever (8.37 cm3), has a maximum power output of 2.05 mW (H = 29.29 μJ/cycle).

A comparative assessment of GIS-based data mining models and a novel ensemble model in groundwater well potential mapping

NASA Astrophysics Data System (ADS)

Naghibi, Seyed Amir; Moghaddam, Davood Davoodi; Kalantar, Bahareh; Pradhan, Biswajeet; Kisi, Ozgur

2017-05-01

In recent years, application of ensemble models has been increased tremendously in various types of natural hazard assessment such as landslides and floods. However, application of this kind of robust models in groundwater potential mapping is relatively new. This study applied four data mining algorithms including AdaBoost, Bagging, generalized additive model (GAM), and Naive Bayes (NB) models to map groundwater potential. Then, a novel frequency ratio data mining ensemble model (FREM) was introduced and evaluated. For this purpose, eleven groundwater conditioning factors (GCFs), including altitude, slope aspect, slope angle, plan curvature, stream power index (SPI), river density, distance from rivers, topographic wetness index (TWI), land use, normalized difference vegetation index (NDVI), and lithology were mapped. About 281 well locations with high potential were selected. Wells were randomly partitioned into two classes for training the models (70% or 197) and validating them (30% or 84). AdaBoost, Bagging, GAM, and NB algorithms were employed to get groundwater potential maps (GPMs). The GPMs were categorized into potential classes using natural break method of classification scheme. In the next stage, frequency ratio (FR) value was calculated for the output of the four aforementioned models and were summed, and finally a GPM was produced using FREM. For validating the models, area under receiver operating characteristics (ROC) curve was calculated. The ROC curve for prediction dataset was 94.8, 93.5, 92.6, 92.0, and 84.4% for FREM, Bagging, AdaBoost, GAM, and NB models, respectively. The results indicated that FREM had the best performance among all the models. The better performance of the FREM model could be related to reduction of over fitting and possible errors. Other models such as AdaBoost, Bagging, GAM, and NB also produced acceptable performance in groundwater modelling. The GPMs produced in the current study may facilitate groundwater exploitation by determining high and very high groundwater potential zones.

Thermoelectric properties of periodic quantum structures in the Wigner-Rode formalism

NASA Astrophysics Data System (ADS)

Kommini, Adithya; Aksamija, Zlatan

2018-01-01

Improving the thermoelectric Seebeck coefficient, while simultaneously reducing thermal conductivity, is required in order to boost thermoelectric (TE) figure of merit (ZT). A common approach to improve the Seebeck coefficient is electron filtering where ‘cold’ (low energy) electrons are restricted from participating in transport by an energy barrier (Kim and Lundstrom 2011 J. Appl. Phys. 110 034511, Zide et al 2010 J. Appl. Phys. 108 123702). However, the impact of electron tunneling through thin barriers and resonant states on TE properties has been given less attention, despite the widespread use of quantum wells and superlattices (SLs) in TE applications. In our work, we develop a comprehensive transport model using the Wigner-Rode formalism. We include the full electronic bandstructure and all the relevant scattering mechanisms, allowing us to simulate both energy relaxation and quantum effects from periodic potential barriers. We study the impact of barrier shape on TE performance and find that tall, sharp barriers with small period lengths lead to the largest increase in both Seebeck coefficient and conductivity, thus boosting power factor and TE efficiency. Our findings are robust against additional elastic scattering such as atomic-scale roughness at side-walls of SL nanowires.

Evaluating Mobile Graphics Processing Units (GPUs) for Real-Time Resource Constrained Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meredith, J; Conger, J; Liu, Y

2005-11-11

Modern graphics processing units (GPUs) can provide tremendous performance boosts for some applications beyond what a single CPU can accomplish, and their performance is growing at a rate faster than CPUs as well. Mobile GPUs available for laptops have the small form factor and low power requirements suitable for use in embedded processing. We evaluated several desktop and mobile GPUs and CPUs on traditional and non-traditional graphics tasks, as well as on the most time consuming pieces of a full hyperspectral imaging application. Accuracy remained high despite small differences in arithmetic operations like rounding. Performance improvements are summarized here relativemore » to a desktop Pentium 4 CPU.« less

New tools for jet analysis in high energy collisions

NASA Astrophysics Data System (ADS)

Duffty, Daniel

Our understanding of the fundamental interactions of particles has come far in the last century, and is still pushing forward. As we build ever more powerful machines to probe higher and higher energies, we will need to develop new tools to not only understand the new physics objects we are trying to detect, but even to understand the environment that we are searching in. We examine methods of identifying both boosted objects and low energy jets which will be shrouded in a sea of noise from other parts of the detector. We display the power of boosted-b tagging in a simulated W search. We also examine the effect of pileup on low energy jet reconstructions. For this purpose we develop a new priority-based jet algorithm, "p-jets", to cluster the energy that belongs together, but ignore the rest.

Power counting to better jet observables

NASA Astrophysics Data System (ADS)

Larkoski, Andrew J.; Moult, Ian; Neill, Duff

2014-12-01

Optimized jet substructure observables for identifying boosted topologies will play an essential role in maximizing the physics reach of the Large Hadron Collider. Ideally, the design of discriminating variables would be informed by analytic calculations in perturbative QCD. Unfortunately, explicit calculations are often not feasible due to the complexity of the observables used for discrimination, and so many validation studies rely heavily, and solely, on Monte Carlo. In this paper we show how methods based on the parametric power counting of the dynamics of QCD, familiar from effective theory analyses, can be used to design, understand, and make robust predictions for the behavior of jet substructure variables. As a concrete example, we apply power counting for discriminating boosted Z bosons from massive QCD jets using observables formed from the n-point energy correlation functions. We show that power counting alone gives a definite prediction for the observable that optimally separates the background-rich from the signal-rich regions of phase space. Power counting can also be used to understand effects of phase space cuts and the effect of contamination from pile-up, which we discuss. As these arguments rely only on the parametric scaling of QCD, the predictions from power counting must be reproduced by any Monte Carlo, which we verify using Pythia 8 and Herwig++. We also use the example of quark versus gluon discrimination to demonstrate the limits of the power counting technique.

Increasing the Air Charge and Scavenging the Clearance Volume of a Compression-Ignition Engine

NASA Technical Reports Server (NTRS)

Spanogle, J A; Hicks, C W; Foster, H H

1934-01-01

The object of the investigation presented in this report was to determine the effects of increasing the air charge and scavenging the clearance volume of a 4-stroke-cycle compression-ignition engine having a vertical-disk form combustion chamber. Boosting the inlet-air pressure with normal valve timing increased the indicated engine power in proportion to the additional air inducted and resulted in smoother engine operation with less combustion shock. Scavenging the clearance volume by using a valve overlap of 145 degrees and an inlet-air boost pressure of approximately 2 1/2 inches of mercury produced a net increase in performance for clear exhaust operation of 33 percent over that obtained with normal valve timing and the same boost pressure. The improved combustion characteristics result in lower specific fuel consumption, and a clearer exhaust.

High average/peak power linearly polarized all-fiber picosecond MOPA seeded by mode-locked noise-like pulses

NASA Astrophysics Data System (ADS)

Yu, H. L.; Ma, P. F.; Tao, R. M.; Wang, X. L.; Zhou, P.; Chen, J. B.

2015-06-01

The characteristics of mode-locked noise-like pulses generated from a passively mode-locked fiber oscillator are experimentally investigated. By carefully adjusting the two polarization controllers, stable mode-locked noise-like pulse emission with a high radio frequency signal/noise ratio of  >55 dB is successfully achieved, ensuring the safety and possibility of high power amplification. To investigate the amplification characteristics of such pulses, one all-fiber master oscillator power amplifier (MOPA) is built to boost the power and energy of such pulses. Amplified noise-like pulses with average output power of 423 W, repetition rate of 18.71 MHz, pulse energy of 22.61 μJ, pulse duration of 72.1 ps and peak power of 314 kW are obtained. Near diffraction-limited beam is also demonstrated with M2 factor measured at full power operation of ~1.2 in the X and Y directions. The polarization extinction ratio at output power of 183 W is measured to be ~13 dB. To the best of our knowledge, this is the first demonstration of high-power amplification of noise-like pulses and the highest peak power ever reported in all-fiber picosecond MOPAs. The temporal self-compression process of such pulses and high peak power when amplified make it an ideal pump source for generation of high-power supercontinuum. Other potential applications, such as material processing and optical coherent tomography, could also be foreseen.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wong, Philip; Lambert, Christine, E-mail: christine.lambert@muhc.mcgill.ca; Agnihotram, Ramanakumar V.

Purpose: Local recurrence (LR) of ductal carcinoma in situ (DCIS) is reduced by whole-breast irradiation after breast-conserving surgery (BCS). However, the benefit of adding a radiotherapy boost to the surgical cavity for DCIS is unclear. We sought to determine the impact of the boost on LR in patients with DCIS treated at the McGill University Health Centre. Methods and Materials: A total of 220 consecutive cases of DCIS treated with BCS and radiotherapy between January 2000 and December 2006 were reviewed. Of the patients, 36% received a radiotherapy boost to the surgical cavity. Median follow-up was 46 months for themore » boost and no-boost groups. Kaplan-Meier survival analyses and Cox regression analyses were performed. Results: Compared with the no-boost group, patients in the boost group more frequently had positive and <0.1-cm margins (48% vs. 8%) (p < 0.0001) and more frequently were in higher-risk categories as defined by the Van Nuys Prognostic (VNP) index (p = 0.006). Despite being at higher risk for LR, none (0/79) of the patients who received a boost experienced LR, whereas 8 of 141 patients who did not receive a boost experienced an in-breast LR (log-rank p = 0.03). Univariate analysis of prognostic factors (age, tumor size, margin status, histological grade, necrosis, and VNP risk category) revealed only the presence of necrosis to significantly correlate with LR (log-rank p = 0.003). The whole-breast irradiation dose and fractionation schedule did not affect LR rate. Conclusions: Our results suggest that the use of a radiotherapy boost improves local control in DCIS and may outweigh the poor prognostic effect of necrosis.« less

Boosted Multivariate Trees for Longitudinal Data

PubMed Central

Pande, Amol; Li, Liang; Rajeswaran, Jeevanantham; Ehrlinger, John; Kogalur, Udaya B.; Blackstone, Eugene H.; Ishwaran, Hemant

2017-01-01

Machine learning methods provide a powerful approach for analyzing longitudinal data in which repeated measurements are observed for a subject over time. We boost multivariate trees to fit a novel flexible semi-nonparametric marginal model for longitudinal data. In this model, features are assumed to be nonparametric, while feature-time interactions are modeled semi-nonparametrically utilizing P-splines with estimated smoothing parameter. In order to avoid overfitting, we describe a relatively simple in sample cross-validation method which can be used to estimate the optimal boosting iteration and which has the surprising added benefit of stabilizing certain parameter estimates. Our new multivariate tree boosting method is shown to be highly flexible, robust to covariance misspecification and unbalanced designs, and resistant to overfitting in high dimensions. Feature selection can be used to identify important features and feature-time interactions. An application to longitudinal data of forced 1-second lung expiratory volume (FEV1) for lung transplant patients identifies an important feature-time interaction and illustrates the ease with which our method can find complex relationships in longitudinal data. PMID:29249866

A Matched-Pair Analysis Comparing Whole-Brain Radiotherapy Plus Stereotactic Radiosurgery Versus Surgery Plus Whole-Brain Radiotherapy and a Boost to the Metastatic Site for One or Two Brain Metastases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rades, Dirk; Department of Radiation Oncology, University Medical Center, Hamburg; Kueter, Jan-Dirk

2009-03-15

Purpose: To compare the results of whole-brain radiotherapy plus stereotactic radiosurgery (WBRT+SRS) with those of surgery plus whole-brain radiotherapy and a boost to the metastatic site (OP+WBRT+boost) for patients with one or two brain metastases. Methods and Materials: Survival, intracerebral control, and local control of the treated metastases were retrospectively evaluated. To reduce the risk of selection bias, a matched-pair analysis was performed. The outcomes of 47 patients who received WBRT+SRS were compared with those of a second cohort of 47 patients who received OP+WBRT+boost. The two treatment groups were matched for the following potential prognostic factors: WBRT schedule, age,more » gender, performance status, tumor type, number of brain metastases, extracerebral metastases, recursive partitioning analysis class, and interval from tumor diagnosis to WBRT. Results: The 1-year survival rates were 65% after WBRT+SRS and 63% after OP+WBRT+boost (p = 0.19). The 1-year intracerebral control rates were 70% and 78% (p = 0.39), respectively. The 1-year local control rates were 84% and 83% (p = 0.87), respectively. On multivariate analyses, improved survival was significantly associated with better performance status (p = 0.009), no extracerebral metastases (p = 0.004), recursive partitioning analysis Class 1 (p = 0.004), and interval from tumor diagnosis to WBRT (p = 0.001). Intracerebral control was not significantly associated with any of the potential prognostic factors. Improved local control was significantly associated with no extracerebral metastases (p = 0.037). Conclusions: Treatment outcomes were not significantly different after WBRT+SRS compared with OP+WBRT+boost. However, WBRT+SRS is less invasive than OP+WBRT+boost and may be preferable for patients with one or two brain metastases. The results should be confirmed by randomized t0011ria.« less

Transformerless dc-Isolated Converter

NASA Technical Reports Server (NTRS)

Rippel, Wally E.

1987-01-01

Efficient voltage converter employs capacitive instead of transformer coupling to provide dc isolation. Offers buck/boost operation, minimal filtering, and low parts count, with possible application in photovoltaic power inverters, power supplies and battery charges. In photovoltaic inverter circuit with transformerless converter, Q2, Q3, Q4, and Q5 form line-commutated inverter. Switching losses and stresses nil because switching performed when current is zero.

Department of Defense high power laser program guidance

NASA Astrophysics Data System (ADS)

Muller, Clifford H.

1994-06-01

The DoD investment of nominally $200 million per year is focused on four high power laser (HPL) concepts: Space-Based Laser (SBL), a Ballistic Missile Defense Organization effort that addresses boost-phase intercept for Theater Missile Defense and National Missile Defense; Airborne Laser (ABL), an Air Force effort that addresses boost-phase intercept for Theater Missile Defense; Ground-Based Laser (GBL), an Air Force effort addressing space control; and Anti-Ship Missile Defense (ASMD), a Navy effort addressing ship-based defense. Each organization is also supporting technology development with the goal of achieving less expensive, brighter, and lighter high power laser systems. These activities represent the building blocks of the DoD program to exploit the compelling characteristics of the high power laser. Even though DoD's HPL program are focused and moderately strong, additional emphasis in a few technical areas could help reduce risk in these programs. In addition, a number of options are available for continuing to use the High-Energy Laser System Test Facility (HELSTF) at White Sands Missile Range. This report provides a brief overview and guidance for the five efforts which comprise the DoD HPL program (SBL, ABL, GBL, ASMD, HELSTF).

A matched-pair analysis comparing whole-brain radiotherapy with and without a stereotactic boost for intracerebral control and overall survival in patients with one to three cerebral metastases.

PubMed

Rades, Dirk; Janssen, Stefan; Bajrovic, Amira; Khoa, Mai Trong; Veninga, Theo; Schild, Steven E

2017-04-24

Twelve years ago, a randomized trial demonstrated that a radiosurgery boost added to whole-brain radiotherapy (WBRT) improved intracerebral control (IC) in patients with one to three cerebral metastases. Overall survival (OS) was improved only in the subgroup of patients with a single metastasis but not in the entire cohort. The present study compared both regimens in a different scenario outside a randomized trial. A total of 252 patients with one to three cerebral metastases were included. Eighty-four patients receiving WBRT plus a planned stereotactic boost and 168 patients receiving WBRT alone were individually matched 1:2 for nine factors including fractionation of WBRT, age, gender, performance score, primary tumor, number of cerebral metastases, extracerebral metastases, recursive partitioning analysis class, and time between cancer diagnosis and WBRT. Each group of three patients was required to match for all nine factors. Both groups were compared for IC and OS. IC rates at 6, 12, 18 and 24 months were 88, 71, 45 and 22% after WBRT plus stereotactic boost vs. 75, 48, 38 and 22% after WBRT alone (p = 0.005). OS rates at 6, 12, 18 and 24 months were 76, 53, 32 and 25% after WBRT plus stereotactic boost and 67, 45, 29 and 20% after WBRT alone (p = 0.10). In patients with a single lesion, OS rates were also not significantly different (p = 0.12). Similar to the previous randomized trial from 2004, this matched-pair study showed that a stereotactic boost in addition to WBRT significantly improved IC but not OS.

Uncovering potential 'herbal probiotics' in Juzen-taiho-to through the study of associated bacterial populations.

PubMed

Montenegro, Diego; Kalpana, Kriti; Chrissian, Christine; Sharma, Ashutosh; Takaoka, Anna; Iacovidou, Maria; Soll, Clifford E; Aminova, Olga; Heguy, Adriana; Cohen, Lisa; Shen, Steven; Kawamura, Akira

2015-02-01

Juzen-taiho-to (JTT) is an immune-boosting formulation of ten medicinal herbs. It is used clinically in East Asia to boost the human immune functions. The active factors in JTT have not been clarified. But, existing evidence suggests that lipopolysaccharide (LPS)-like factors contribute to the activity. To examine this possibility, JTT was subjected to a series of analyses, including high resolution mass spectrometry, which suggested the presence of structural variants of LPS. This finding opened a possibility that JTT contains immune-boosting bacteria. As the first step to characterize the bacteria in JTT, 16S ribosomal RNA sequencing was carried out for Angelica sinensis (dried root), one of the most potent immunostimulatory herbs in JTT. The sequencing revealed a total of 519 bacteria genera in A. sinensis. The most abundant genus was Rahnella, which is widely distributed in water and plants. The abundance of Rahnella appeared to correlate with the immunostimulatory activity of A. sinensis. In conclusion, the current study provided new pieces of evidence supporting the emerging theory of bacterial contribution in immune-boosting herbs. Copyright © 2014 Elsevier Ltd. All rights reserved.

Effects of temperature and pressure on the performance of a solid oxide fuel cell running on steam reformate of kerosene

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chick, Lawrence A.; Marina, Olga A.; Coyle, Christopher A.

2013-08-15

A button solid oxide fuel cell with a La0.6Sr0.4Co0.2Fe0.8O3 cathode and a nickel-YSZ anode was tested over a range of temperatures from 650 to 800°C and a range of pressures from 101 to 724 kPa. The fuel was simulated steam-reformed kerosene and the oxidant was air. The observed increases in open circuit voltages (OCV) were accurately predicted by the Nernst equation. Kinetics also increased, although the power boost due to kinetics was about two thirds as large as the boost due to OCV. The total power boost in going from 101 to 724 kPa at 750°C and 0.8 volts wasmore » 66%. Impedance spectroscopy demonstrated a significant decrease in electrodic losses at elevated pressures. Complex impedance spectra were dominated by a combination of low frequency processes that decreased markedly with increasing pressure. A composite of high-frequency processes also decreased with pressure, but to a lesser extent. An empirical algorithm that accurately predicts the increased fuel cell performance at elevated pressures was developed for our results and was also suitable for some, but not all, data reported in the literature.« less

JPRS Report, Near East and South Asia.

DTIC Science & Technology

1991-07-31

of peace following the Gulf lomatic means in our power to put additional pressure war become a mere illusion? on Israel to agree to a conference and...countries’ interests are crushed in the were extremely damaged by the Gulf war as a result of face of rivalries among the powerful . All this undermines...demographic growth. Their economic As you can see, the work of this North African commis- policy boosted purchasing power , which raised the rate sion is

Improved Access to Supercomputers Boosts Chemical Applications.

ERIC Educational Resources Information Center

Borman, Stu

1989-01-01

Supercomputing is described in terms of computing power and abilities. The increase in availability of supercomputers for use in chemical calculations and modeling are reported. Efforts of the National Science Foundation and Cray Research are highlighted. (CW)

Modelling, analyses and design of switching converters

NASA Technical Reports Server (NTRS)

Cuk, S. M.; Middlebrook, R. D.

1978-01-01

A state-space averaging method for modelling switching dc-to-dc converters for both continuous and discontinuous conduction mode is developed. In each case the starting point is the unified state-space representation, and the end result is a complete linear circuit model, for each conduction mode, which correctly represents all essential features, namely, the input, output, and transfer properties (static dc as well as dynamic ac small-signal). While the method is generally applicable to any switching converter, it is extensively illustrated for the three common power stages (buck, boost, and buck-boost). The results for these converters are then easily tabulated owing to the fixed equivalent circuit topology of their canonical circuit model. The insights that emerge from the general state-space modelling approach lead to the design of new converter topologies through the study of generic properties of the cascade connection of basic buck and boost converters.

Maximum power point tracking for photovoltaic applications by using two-level DC/DC boost converter

NASA Astrophysics Data System (ADS)

Moamaei, Parvin

Recently, photovoltaic (PV) generation is becoming increasingly popular in industrial applications. As a renewable and alternative source of energy they feature superior characteristics such as being clean and silent along with less maintenance problems compared to other sources of the energy. In PV generation, employing a Maximum Power Point Tracking (MPPT) method is essential to obtain the maximum available solar energy. Among several proposed MPPT techniques, the Perturbation and Observation (P&O;) and Model Predictive Control (MPC) methods are adopted in this work. The components of the MPPT control system which are P&O; and MPC algorithms, PV module and high gain DC-DC boost converter are simulated in MATLAB Simulink. They are evaluated theoretically under rapidly and slowly changing of solar irradiation and temperature and their performance is shown by the simulation results, finally a comprehensive comparison is presented.

Optimized MPPT algorithm for boost converters taking into account the environmental variables

NASA Astrophysics Data System (ADS)

Petit, Pierre; Sawicki, Jean-Paul; Saint-Eve, Frédéric; Maufay, Fabrice; Aillerie, Michel

2016-07-01

This paper presents a study on the specific behavior of the Boost DC-DC converters generally used for powering conversion of PV panels connected to a HVDC (High Voltage Direct Current) Bus. It follows some works pointing out that converter MPPT (Maximum Power Point Tracker) is severely perturbed by output voltage variations due to physical dependency of parameters as the input voltage, the output voltage and the duty cycle of the PWM switching control of the MPPT. As a direct consequence many converters connected together on a same load perturb each other because of the output voltage variations induced by fluctuations on the HVDC bus essentially due to a not insignificant bus impedance. In this paper we show that it is possible to include an internal computed variable in charge to compensate local and external variations to take into account the environment variables.

A High-Efficiency Wind Energy Harvester for Autonomous Embedded Systems

PubMed Central

Brunelli, Davide

2016-01-01

Energy harvesting is currently a hot research topic, mainly as a consequence of the increasing attractiveness of computing and sensing solutions based on small, low-power distributed embedded systems. Harvesting may enable systems to operate in a deploy-and-forget mode, particularly when power grid is absent and the use of rechargeable batteries is unattractive due to their limited lifetime and maintenance requirements. This paper focuses on wind flow as an energy source feasible to meet the energy needs of a small autonomous embedded system. In particular the contribution is on the electrical converter and system integration. We characterize the micro-wind turbine, we define a detailed model of its behaviour, and then we focused on a highly efficient circuit to convert wind energy into electrical energy. The optimized design features an overall volume smaller than 64 cm3. The core of the harvester is a high efficiency buck-boost converter which performs an optimal power point tracking. Experimental results show that the wind generator boosts efficiency over a wide range of operating conditions. PMID:26959018

A High-Efficiency Wind Energy Harvester for Autonomous Embedded Systems.

PubMed

Brunelli, Davide

2016-03-04

Energy harvesting is currently a hot research topic, mainly as a consequence of the increasing attractiveness of computing and sensing solutions based on small, low-power distributed embedded systems. Harvesting may enable systems to operate in a deploy-and-forget mode, particularly when power grid is absent and the use of rechargeable batteries is unattractive due to their limited lifetime and maintenance requirements. This paper focuses on wind flow as an energy source feasible to meet the energy needs of a small autonomous embedded system. In particular the contribution is on the electrical converter and system integration. We characterize the micro-wind turbine, we define a detailed model of its behaviour, and then we focused on a highly efficient circuit to convert wind energy into electrical energy. The optimized design features an overall volume smaller than 64 cm³. The core of the harvester is a high efficiency buck-boost converter which performs an optimal power point tracking. Experimental results show that the wind generator boosts efficiency over a wide range of operating conditions.

75 FR 79317 - Airworthiness Directives; The Boeing Company Model 737-600, -700, -700C, -800, and -900 Series...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-20

... replacement of the power control relays in the P91 and P92 power distribution panels for the fuel boost and override pumps with new, improved relays having a ground fault interrupter (GFI) feature, or installation... specify which relays may be replaced by GFIs or UFIs. We are proposing this AD to prevent pump housing...

Indirect current control with separate IZ drop compensation for voltage source converters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kanetkar, V.R.; Dawande, M.S.; Dubey, G.K.

1995-12-31

Indirect Current Control (ICC) of boost type Voltage Source Converters (VSCs) using separate compensation of line IZ voltage drop is presented. A separate bi-directional VSC is used to produce the compensation voltage. This simplifies the ICC regulator scheme as the power flow is controlled through single modulation index. Experimental verification is provided for bi-directional control of the power flow.

Estimation of energetic efficiency of heat supply in front of the aircraft at supersonic accelerated flight. Part II. Mathematical model of the trajectory boost part and computational results

NASA Astrophysics Data System (ADS)

Latypov, A. F.

2009-03-01

The fuel economy was estimated at boost trajectory of aerospace plane during energy supply to the free stream. Initial and final velocities of the flight were given. A model of planning flight above cold air in infinite isobaric thermal wake was used. The comparison of fuel consumption was done at optimal trajectories. The calculations were done using a combined power plant consisting of ramjet and liquid-propellant engine. An exergy model was constructed in the first part of the paper for estimating the ramjet thrust and specific impulse. To estimate the aerodynamic drag of aircraft a quadratic dependence on aerodynamic lift is used. The energy for flow heating is obtained at the sacrifice of an equivalent decrease of exergy of combustion products. The dependencies are obtained for increasing the range coefficient of cruise flight at different Mach numbers. In the second part of the paper, a mathematical model is presented for the boost part of the flight trajectory of the flying vehicle and computational results for reducing the fuel expenses at the boost trajectory at a given value of the energy supplied in front of the aircraft.

An Ultra-Wideband Cross-Correlation Radiometer for Mesoscopic Experiments

NASA Astrophysics Data System (ADS)

Toonen, Ryan; Haselby, Cyrus; Qin, Hua; Eriksson, Mark; Blick, Robert

2007-03-01

We have designed, built and tested a cross-correlation radiometer for detecting statistical order in the quantum fluctuations of mesoscopic experiments at sub-Kelvin temperatures. Our system utilizes a fully analog front-end--operating over the X- and Ku-bands (8 to 18 GHz)--for computing the cross-correlation function. Digital signal processing techniques are used to provide robustness against instrumentation drifts and offsets. The economized version of our instrument can measure, with sufficient correlation efficiency, noise signals having power levels as low as 10 fW. We show that, if desired, we can improve this performance by including cryogenic preamplifiers which boost the signal-to-noise ratio near the signal source. By adding a few extra components, we can measure both the real and imaginary parts of the cross-correlation function--improving the overall signal-to-noise ratio by a factor of sqrt[2]. We demonstrate the utility of our cross-correlator with noise power measurements from a quantum point contact.

Enhanced power conversion efficiency in InGaN-based solar cells via graded composition multiple quantum wells.

PubMed

Tsai, Yu-Lin; Wang, Sheng-Wen; Huang, Jhih-Kai; Hsu, Lung-Hsing; Chiu, Ching-Hsueh; Lee, Po-Tsung; Yu, Peichen; Lin, Chien-Chung; Kuo, Hao-Chung

2015-11-30

This work demonstrates the enhanced power conversion efficiency (PCE) in InGaN/GaN multiple quantum well (MQWs) solar cells with gradually decreasing indium composition in quantum wells (GQWs) toward p-GaN as absorber. The GQW can improve the fill factor from 42% to 62% and enhance the short current density from 0.8 mA/cm² to 0.92 mA/cm², as compares to the typical MQW solar cells. As a result, the PCE is boosted from 0.63% to 1.11% under AM1.5G illumination. Based on simulation and experimental results, the enhanced PCE can be attributed to the improved carrier collection in GQW caused by the reduction of potential barriers and piezoelectric polarization induced fields near the p-GaN layer. The presented concept paves a way toward highly efficient InGaN-based solar cells and other GaN-related MQW devices.

Modeling and sizing the coil in boost converters dedicated to photovoltaic sources

NASA Astrophysics Data System (ADS)

Atik, Lotfi; Fares, Mohammed Amine; Zaraket, Jean; Bachir, Ghalem; Aillerie, Michel

2018-05-01

The coil is a very important element in a wide range of power electrical systems as such as those used in converter or inverter dedicated to extract and to adapt the value and the shape of the intensity and the voltage delivered by renewable energy sources. Thus, knowing its behavior in converters is paramount to obtain a maximum conversion efficiency and reliability. In this context, this paper presents a global study of a DC/DC boost converter dedicated to photovoltaic sources based on the modeling of the behavior of the coil or the inductance as a function of the switching frequency.

Particle tower technology applied to metallurgic plants and peak-time boosting of steam power plants

NASA Astrophysics Data System (ADS)

Amsbeck, Lars; Buck, Reiner; Prosin, Tobias

2016-05-01

Using solar tower technology with ceramic particles as heat transfer and storage medium to preheat scrap for induction furnaces in foundries provides solar generated heat to save electricity. With such a system an unsubsidized payback time of only 4 years is achieved for a 70000t/a foundry in Brazil. The same system can be also used for heat treatment of metals. If electricity is used to heat inert atmospheres a favorable economic performance is also achievable for the particle system. The storage in a particle system enables solar boosting to be restricted to only peak times, enabling an interesting business case opportunity.

The Spirit of France

DTIC Science & Technology

1994-01-01

seemed to boost self esteem amongst the French , giving France a greater sense of dignity. Charles de Gaulle sought grandeur to unite France and give...overshadowed by the US, UK and Russia. The war had left France with little influence in Europe and had psychologically and morally weakened the French ... France as a way to increase the influence base of the French state. Influence, either perceived or real, meant power. Power represented independence

THE FASTEST OODA LOOP: THE IMPLICATIONS OF BIG DATA FOR AIR POWER

DTIC Science & Technology

2016-06-01

AIR COMMAND AND STAFF COLLEGE AIR UNIVERSITY THE FASTEST OODA LOOP : THE IMPLICATIONS OF BIG DATA FOR AIR POWER by Aaron J. Dove, Maj, USAF A...Use of Big Data Thus Far..............................................................16 The Big Data Boost To The OODA Loop ...processed with enough accuracy that it required minimal to no human or man-in-the loop vetting of the information through Command and Control (C2

Second Stage (S-II) Plays Key Role in Apollo missions

NASA Technical Reports Server (NTRS)

1970-01-01

This photograph of the Saturn V Second Stage (S-II) clearly shows the cluster of five powerful J-2 engines needed to boost the Apollo spacecraft into earth orbit following first stage separation. The towering 363-foot Saturn V was a multi-stage, multi-engine launch vehicle standing taller than the Statue of Liberty. Altogether, the Saturn V engines produced as much power as 85 Hoover Dams.

Integrating DC/DC Conversion with Possible Reconfiguration within Submodule Solar Photovoltaic Systems

NASA Astrophysics Data System (ADS)

Huang, Peter Jen-Hung

This research first proposes a method to merge photovoltaic (PV) cells or PV panels within the internal components DC-DC converters. The purpose of this merged structure is to reconfigure the PV modules between series and parallel connections using high switching frequencies (hundreds of kHz). This leads to multi-levels of voltages and currents that become applied to the output filter of the converter. Further, this research introduces a concept of a switching cell that utilizes the reconfiguration of series and parallel connections in DC-DC converters. The switching occurs at high switching frequency and the switches can be integrated to be within the solar panels or in between the solar cells. The concept is generalized and applied to basic buck and boost topologies. As examples of the new types of converters: reconfigurable PV-buck and PV-boost converter topologies are presented. It is also possible to create other reconfigurable power converters: non-isolated and isolated topologies. Analysis, simulation and experimental verification for the reconfigurable PV-buck and PV-boost converters are presented extensively to illustrate proof of concept. Benefits and drawbacks of the new approach are discussed. The second part of this research proposes to utilize the internal solar cell capacitance and internal solar module wire parasitic inductances to replace the input capacitor and filter inductor in boost derived DC-DC converters for energy harvesting applications. High switching frequency (MHz) hard switched and resonant boost converters are proposed. Their analysis, simulation and experimental prototypes are presented. A specific proof-of-concept application is especially tested for foldable PV panels, which are known for their high internal wire inductance. The experimental converters successfully boost solar module voltage without adding any external input capacitance or filter inductor. Benefits and drawbacks of new proposed PV submodule integrated boost converters are discussed.

A new kind of low-inductance transformer type magnetic switch (TTMS) with coaxial cylindrical conductors

NASA Astrophysics Data System (ADS)

Zhang, Yu; Liu, Jinliang

2013-02-01

As important devices for voltage boosting and switching, respectively, pulse transformer and magnetic switch are widely used in pulsed power technology. In this paper, a new kind of transformer type magnetic switch (TTMS) with coaxial cylindrical conductors is put forward to combine the functions of voltage boosting and switching in one power device. As a compact combination device of discrete pulse transformer and magnetic switch, the compact TTMS decreases the required volume of magnetic cores in a large scale. The primary windings of the TTMS have a parallel combination structure so that the TTMS which only has 3 turns of secondary windings has a step-up ratio at 1:9. Before the magnetic core saturates, the TTMS has low unsaturated inductances of windings and good pulse response characteristics, so it can be used to substitute the Marx generator to charge the pulse forming line (PFL) at the ranges of several hundred kV and several hundred ns. After the core saturates, the cylindrical conductors can decrease the saturated inductance of the secondary windings of TTMS to a level less than 400 nH. As a result, the proposed TTMS can be used as the boosting transformer and main switch of helical Blumlein PFL to form the quasi-square voltage pulse on the 160 Ω load with a short pulse rise time only at 60 ns.

Buck-boost converter for simultaneous semi-active vibration control and energy harvesting for electromagnetic regenerative shock absorber

NASA Astrophysics Data System (ADS)

Li, Peng; Zhang, Chongxiao; Kim, Junyoung; Yu, Liangyao; Zuo, Lei

2014-04-01

Regenerative semi-active suspensions can capture the previously dissipated vibration energy and convert it to usable electrical energy for powering on-board electronic devices, while achieve both the better ride comfort and improved road handling performance at the same time when certain control is applied. To achieve this objective, the power electronics interface circuit connecting the energy harvester and the electrical loads, which can perform simultaneous vibration control and energy harvesting function is in need. This paper utilized a buck-boost converter for simultaneous semi-active vibration control and energy harvesting with electromagnetic regenerative shock absorber, which utilizes a rotational generator to converter the vibration energy to electricity. It has been found that when the circuit works in discontinuous current mode (DCM), the ratio between the input voltage and current is only related to the duty cycle of the switch pulse width modulation signal. Using this property, the buck-boost converter can be used to perform semi-active vibration control by controlling the load connected between the terminals of the generator in the electromagnetic shock absorber. While performing the vibration control, the circuit always draw current from the shock absorber and the suspension remain dissipative, and the shock absorber takes no additional energy to perform the vibration control. The working principle and dynamics of the circuit has been analyzed and simulations were performed to validate the concept.

A new kind of low-inductance transformer type magnetic switch (TTMS) with coaxial cylindrical conductors.

PubMed

Zhang, Yu; Liu, Jinliang

2013-02-01

As important devices for voltage boosting and switching, respectively, pulse transformer and magnetic switch are widely used in pulsed power technology. In this paper, a new kind of transformer type magnetic switch (TTMS) with coaxial cylindrical conductors is put forward to combine the functions of voltage boosting and switching in one power device. As a compact combination device of discrete pulse transformer and magnetic switch, the compact TTMS decreases the required volume of magnetic cores in a large scale. The primary windings of the TTMS have a parallel combination structure so that the TTMS which only has 3 turns of secondary windings has a step-up ratio at 1:9. Before the magnetic core saturates, the TTMS has low unsaturated inductances of windings and good pulse response characteristics, so it can be used to substitute the Marx generator to charge the pulse forming line (PFL) at the ranges of several hundred kV and several hundred ns. After the core saturates, the cylindrical conductors can decrease the saturated inductance of the secondary windings of TTMS to a level less than 400 nH. As a result, the proposed TTMS can be used as the boosting transformer and main switch of helical Blumlein PFL to form the quasi-square voltage pulse on the 160 Ω load with a short pulse rise time only at 60 ns.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gill, Beant S.; Lin, Jeff F.; Krivak, Thomas C.

Purpose: To utilize the National Cancer Data Base to evaluate trends in brachytherapy and alternative radiation therapy utilization in the treatment of cervical cancer, to identify associations with outcomes between the various radiation therapy modalities. Methods and Materials: Patients with International Federation of Gynecology and Obstetrics stage IIB-IVA cervical cancer in the National Cancer Data Base who received treatment from January 2004 to December 2011 were analyzed. Overall survival was estimated by the Kaplan-Meier method. Univariate and multivariable analyses were performed to identify factors associated with type of boost radiation modality used and its impact on survival. Results: A totalmore » of 7654 patients had information regarding boost modality. A predominant proportion of patients were Caucasian (76.2%), had stage IIIB (48.9%) disease with squamous (82.0%) histology, were treated at academic/research centers (47.7%) in the South (34.8%), and lived 0 to 5 miles (27.9%) from the treating facility. A majority received brachytherapy (90.3%). From 2004 to 2011, brachytherapy use decreased from 96.7% to 86.1%, whereas intensity modulated radiation therapy (IMRT) and stereotactic body radiation therapy (SBRT) use increased from 3.3% to 13.9% in the same period (P<.01). Factors associated with decreased brachytherapy utilization included older age, stage IVA disease, smaller tumor size, later year of diagnosis, lower-volume treatment centers, and facility type. After controlling for significant factors from survival analyses, IMRT or SBRT boost resulted in inferior overall survival (hazard ratio, 1.86; 95% confidence interval, 1.35-2.55; P<.01) as compared with brachytherapy. In fact, the survival detriment associated with IMRT or SBRT boost was stronger than that associated with excluding chemotherapy (hazard ratio, 1.61′ 95% confidence interval, 1.27-2.04′ P<.01). Conclusions: Consolidation brachytherapy is a critical treatment component for locally advanced cervical cancer; however, there has been declining utilization of brachytherapy. Increased use of IMRT and SBRT boost coupled with increased mortality risk should raise concerns about utilizing these approaches over brachytherapy.« less

Robust boosting via convex optimization

NASA Astrophysics Data System (ADS)

Rätsch, Gunnar

2001-12-01

In this work we consider statistical learning problems. A learning machine aims to extract information from a set of training examples such that it is able to predict the associated label on unseen examples. We consider the case where the resulting classification or regression rule is a combination of simple rules - also called base hypotheses. The so-called boosting algorithms iteratively find a weighted linear combination of base hypotheses that predict well on unseen data. We address the following issues: o The statistical learning theory framework for analyzing boosting methods. We study learning theoretic guarantees on the prediction performance on unseen examples. Recently, large margin classification techniques emerged as a practical result of the theory of generalization, in particular Boosting and Support Vector Machines. A large margin implies a good generalization performance. Hence, we analyze how large the margins in boosting are and find an improved algorithm that is able to generate the maximum margin solution. o How can boosting methods be related to mathematical optimization techniques? To analyze the properties of the resulting classification or regression rule, it is of high importance to understand whether and under which conditions boosting converges. We show that boosting can be used to solve large scale constrained optimization problems, whose solutions are well characterizable. To show this, we relate boosting methods to methods known from mathematical optimization, and derive convergence guarantees for a quite general family of boosting algorithms. o How to make Boosting noise robust? One of the problems of current boosting techniques is that they are sensitive to noise in the training sample. In order to make boosting robust, we transfer the soft margin idea from support vector learning to boosting. We develop theoretically motivated regularized algorithms that exhibit a high noise robustness. o How to adapt boosting to regression problems? Boosting methods are originally designed for classification problems. To extend the boosting idea to regression problems, we use the previous convergence results and relations to semi-infinite programming to design boosting-like algorithms for regression problems. We show that these leveraging algorithms have desirable theoretical and practical properties. o Can boosting techniques be useful in practice? The presented theoretical results are guided by simulation results either to illustrate properties of the proposed algorithms or to show that they work well in practice. We report on successful applications in a non-intrusive power monitoring system, chaotic time series analysis and a drug discovery process. --- Anmerkung: Der Autor ist Träger des von der Mathematisch-Naturwissenschaftlichen Fakultät der Universität Potsdam vergebenen Michelson-Preises für die beste Promotion des Jahres 2001/2002. In dieser Arbeit werden statistische Lernprobleme betrachtet. Lernmaschinen extrahieren Informationen aus einer gegebenen Menge von Trainingsmustern, so daß sie in der Lage sind, Eigenschaften von bisher ungesehenen Mustern - z.B. eine Klassenzugehörigkeit - vorherzusagen. Wir betrachten den Fall, bei dem die resultierende Klassifikations- oder Regressionsregel aus einfachen Regeln - den Basishypothesen - zusammengesetzt ist. Die sogenannten Boosting Algorithmen erzeugen iterativ eine gewichtete Summe von Basishypothesen, die gut auf ungesehenen Mustern vorhersagen. Die Arbeit behandelt folgende Sachverhalte: o Die zur Analyse von Boosting-Methoden geeignete Statistische Lerntheorie. Wir studieren lerntheoretische Garantien zur Abschätzung der Vorhersagequalität auf ungesehenen Mustern. Kürzlich haben sich sogenannte Klassifikationstechniken mit großem Margin als ein praktisches Ergebnis dieser Theorie herausgestellt - insbesondere Boosting und Support-Vektor-Maschinen. Ein großer Margin impliziert eine hohe Vorhersagequalität der Entscheidungsregel. Deshalb wird analysiert, wie groß der Margin bei Boosting ist und ein verbesserter Algorithmus vorgeschlagen, der effizient Regeln mit maximalem Margin erzeugt. o Was ist der Zusammenhang von Boosting und Techniken der konvexen Optimierung? Um die Eigenschaften der entstehenden Klassifikations- oder Regressionsregeln zu analysieren, ist es sehr wichtig zu verstehen, ob und unter welchen Bedingungen iterative Algorithmen wie Boosting konvergieren. Wir zeigen, daß solche Algorithmen benutzt werden koennen, um sehr große Optimierungsprobleme mit Nebenbedingungen zu lösen, deren Lösung sich gut charakterisieren laesst. Dazu werden Verbindungen zum Wissenschaftsgebiet der konvexen Optimierung aufgezeigt und ausgenutzt, um Konvergenzgarantien für eine große Familie von Boosting-ähnlichen Algorithmen zu geben. o Kann man Boosting robust gegenüber Meßfehlern und Ausreissern in den Daten machen? Ein Problem bisheriger Boosting-Methoden ist die relativ hohe Sensitivität gegenüber Messungenauigkeiten und Meßfehlern in der Trainingsdatenmenge. Um dieses Problem zu beheben, wird die sogenannte 'Soft-Margin' Idee, die beim Support-Vector Lernen schon benutzt wird, auf Boosting übertragen. Das führt zu theoretisch gut motivierten, regularisierten Algorithmen, die ein hohes Maß an Robustheit aufweisen. o Wie kann man die Anwendbarkeit von Boosting auf Regressionsprobleme erweitern? Boosting-Methoden wurden ursprünglich für Klassifikationsprobleme entwickelt. Um die Anwendbarkeit auf Regressionsprobleme zu erweitern, werden die vorherigen Konvergenzresultate benutzt und neue Boosting-ähnliche Algorithmen zur Regression entwickelt. Wir zeigen, daß diese Algorithmen gute theoretische und praktische Eigenschaften haben. o Ist Boosting praktisch anwendbar? Die dargestellten theoretischen Ergebnisse werden begleitet von Simulationsergebnissen, entweder, um bestimmte Eigenschaften von Algorithmen zu illustrieren, oder um zu zeigen, daß sie in der Praxis tatsächlich gut funktionieren und direkt einsetzbar sind. Die praktische Relevanz der entwickelten Methoden wird in der Analyse chaotischer Zeitreihen und durch industrielle Anwendungen wie ein Stromverbrauch-Überwachungssystem und bei der Entwicklung neuer Medikamente illustriert.

Experimental Study of RF Energy Transfer System in Indoor Environment

NASA Astrophysics Data System (ADS)

Adami, S.-E.; Proynov, P. P.; Stark, B. H.; Hilton, G. S.; Craddock, I. J.

2014-11-01

This paper presents a multi-transmitter, 2.43 GHz Radio-Frequency (RF) wireless power transfer (WPT) system for powering on-body devices. It is shown that under typical indoor conditions, the received power range spans several orders of magnitude from microwatts to milliwatts. A body-worn dual-polarised rectenna (rectifying antenna) is presented, designed for situations where the dominant polarization is unpredictable, as is the case for the on-body sensors. Power management circuitry is demonstrated that optimally loads the rectenna even under highly intermittent conditions, and boosts the voltage to charge an on-board storage capacitor.

High-frequency high-voltage high-power DC-to-DC converters

NASA Technical Reports Server (NTRS)

Wilson, T. G.; Owen, H. A.; Wilson, P. M.

1982-01-01

A simple analysis of the current and voltage waveshapes associated with the power transistor and the power diode in an example current-or-voltage step-up (buck-boost) converter is presented. The purpose of the analysis is to provide an overview of the problems and design trade-offs which must be addressed as high-power high-voltage converters are operated at switching frequencies in the range of 100 kHz and beyond. Although the analysis focuses on the current-or-voltage step-up converter as the vehicle for discussion, the basic principles presented are applicable to other converter topologies as well.

High-frequency high-voltage high-power DC-to-DC converters

NASA Astrophysics Data System (ADS)

Wilson, T. G.; Owen, H. A.; Wilson, P. M.

1982-09-01

A simple analysis of the current and voltage waveshapes associated with the power transistor and the power diode in an example current-or-voltage step-up (buck-boost) converter is presented. The purpose of the analysis is to provide an overview of the problems and design trade-offs which must be addressed as high-power high-voltage converters are operated at switching frequencies in the range of 100 kHz and beyond. Although the analysis focuses on the current-or-voltage step-up converter as the vehicle for discussion, the basic principles presented are applicable to other converter topologies as well.

Quality of Life in Women Undergoing Breast Irradiation in a Randomized, Controlled Clinical Trial Evaluating Different Tumor Bed Boost Fractionations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Finkel, Morgan A.; Cooper, Benjamin T.; Li, Xiaochun

Purpose: To identify differences in breast cancer patient-reported quality of life (QOL) between 2 radiation tumor bed boost dose regimens. Methods and Materials: Four hundred patients with stage 0, I, or II breast cancer who underwent segmental mastectomy with sentinel node biopsy and/or axillary node dissection were treated with either a daily or weekly boost. Patients were treated prone to 40.5 Gy/15 fractions to the whole breast, 5 days per week. Patients were randomized to a concomitant daily boost to the tumor bed of 0.5 Gy, or a weekly boost of 2 Gy on Friday. Patients completed 6 validated QOL survey instruments at baseline,more » last week of treatment (3 weeks), 45-60 days from the completion of radiation treatment, and at 2-year follow-up. Results: There were no statistically significance differences in responses to the 6 QOL instruments between the daily and weekly radiation boost regimens, even after adjustment for important covariates. However, several changes in responses over time occurred in both arms, including worsening functional status, cosmetic status, and breast-specific pain at the end of treatment as compared with before and 45 to 60 days after the conclusion of treatment. Conclusions: Whole-breast, prone intensity modulated radiation has similar outcomes in QOL measures whether given with a daily or weekly boost. This trial has generated the foundation for a current study of weekly versus daily radiation boost in women with early breast cancer in which 3-dimensional conformal radiation is allowed as a prospective stratification factor.« less

Responsivity boosting in FIR TiN LEKIDs using phonon recycling: simulations and array design

NASA Astrophysics Data System (ADS)

Fyhrie, Adalyn; McKenney, Christopher; Glenn, Jason; LeDuc, Henry G.; Gao, Jiansong; Day, Peter; Zmuidzinas, Jonas

2016-07-01

To characterize further the cosmic star formation history at high redshifts, a large-area survey by a cryogenic 4-6 meter class telescope with a focal plane populated by tens of thousands of far-infrared (FIR, 30-300 μm) detectors with broadband detector noise equivalent powers (NEPs) on the order of 3×10-9 W/√ Hz is needed. Ideal detectors for such a surveyor do not yet exist. As a demonstration of one technique for approaching the ultra-low NEPs required by this surveyor, we present the design of an array of 96 350 µm KIDs that utilize phonon recycling to boost responsivity. Our KID array is fabricated with TiN deposited on a silicon-on-insulator (SOI) wafer, which is a 2 μm thick layer of silicon bonded to a thicker slab of silicon by a thin oxide layer. The backside thick slab is etched away underneath the absorbers so that the inductors are suspended on just the 2 μm membrane. The intent is that quasiparticle recombination phonons are trapped in the thin membrane, thereby increasing their likelihood of being re-absorbed by the KID to break additional Cooper pairs and boost responsivity. We also present a Monte-Carlo simulation that predicts the amount of signal boost expected from phonon recycling given different detector geometries and illumination strategies. For our current array geometry, the simulation predicts a measurable 50% boost in responsivity.

Persistence of Protective Immunity to Malaria Induced by DNA Priming and Poxvirus Boosting: Characterization of Effector and Memory CD8+-T-Cell Populations

PubMed Central

Sedegah, Martha; Brice, Gary T.; Rogers, William O.; Doolan, Denise L.; Charoenvit, Yupin; Jones, Trevor R.; Majam, Victoria F.; Belmonte, Arnel; Lu, Minh; Belmonte, Maria; Carucci, Daniel J.; Hoffman, Stephen L.

2002-01-01

The persistence of immunity to malaria induced in mice by a heterologous DNA priming and poxvirus boosting regimen was characterized. Mice were immunized by priming with DNA vaccine plasmids encoding the Plasmodium yoelii circumsporozoite protein (PyCSP) and murine granulocyte-macrophage colony-stimulating factor and boosting with recombinant vaccinia encoding PyCSP. BALB/c mice immunized with either high-dose (100 μg of p PyCSP plus 30 μg of pGM-CSF) or low-dose (1 μg of p PyCSP plus 1 μg of pGM-CSF DNA) priming were protected against challenge with 50 P. yoelii sporozoites. Protection 2 weeks after immunization was 70 to 100%, persisted at this level for at least 20 weeks, and declined to 30 to 40% by 28 weeks. Eight of eight mice protected at 20 weeks were still protected when rechallenged at 40 weeks. The antigen (Ag)-specific effector CD8+-T-cell population present 2 weeks after boosting had ex vivo Ag-specific cytolytic activity, expressed both gamma interferon (IFN-γ) and tumor necrosis factor alpha, and constituted 12 to 20% of splenic CD8+ T cells. In contrast, the memory CD8+-Ag-specific-cell population at 28 weeks lacked cytolytic activity and constituted only 6% of splenic CD8+ T cells, but at the single-cell level it produced significantly higher levels of IFN-γ than the effectors. High levels of Ag- or parasite-specific antibodies present 2 weeks after boosting had declined three- to sevenfold by 28 weeks. Low-dose priming was similarly immunogenic and as protective as high-dose priming against a 50-, but not a 250-, sporozoite challenge. These results demonstrate that a heterologous priming and boosting vaccination can provide lasting protection against malaria in this model system. PMID:12065488

EPS-LASSO: Test for High-Dimensional Regression Under Extreme Phenotype Sampling of Continuous Traits.

PubMed

Xu, Chao; Fang, Jian; Shen, Hui; Wang, Yu-Ping; Deng, Hong-Wen

2018-01-25

Extreme phenotype sampling (EPS) is a broadly-used design to identify candidate genetic factors contributing to the variation of quantitative traits. By enriching the signals in extreme phenotypic samples, EPS can boost the association power compared to random sampling. Most existing statistical methods for EPS examine the genetic factors individually, despite many quantitative traits have multiple genetic factors underlying their variation. It is desirable to model the joint effects of genetic factors, which may increase the power and identify novel quantitative trait loci under EPS. The joint analysis of genetic data in high-dimensional situations requires specialized techniques, e.g., the least absolute shrinkage and selection operator (LASSO). Although there are extensive research and application related to LASSO, the statistical inference and testing for the sparse model under EPS remain unknown. We propose a novel sparse model (EPS-LASSO) with hypothesis test for high-dimensional regression under EPS based on a decorrelated score function. The comprehensive simulation shows EPS-LASSO outperforms existing methods with stable type I error and FDR control. EPS-LASSO can provide a consistent power for both low- and high-dimensional situations compared with the other methods dealing with high-dimensional situations. The power of EPS-LASSO is close to other low-dimensional methods when the causal effect sizes are small and is superior when the effects are large. Applying EPS-LASSO to a transcriptome-wide gene expression study for obesity reveals 10 significant body mass index associated genes. Our results indicate that EPS-LASSO is an effective method for EPS data analysis, which can account for correlated predictors. The source code is available at https://github.com/xu1912/EPSLASSO. hdeng2@tulane.edu. Supplementary data are available at Bioinformatics online. © The Author (2018). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

Centaur boost pump turbine icing investigation

NASA Technical Reports Server (NTRS)

Rollbuhler, R. J.

1976-01-01

An investigation was conducted to determine if ice formation in the Centaur vehicle liquid oxygen boost pump turbine could prevent rotation of the pump and whether or not this phenomenon could have been the failure mechanism for the Titan/Centaur vehicle TC-1. The investigation consisted of a series of tests done in the LeRC Space Power Chamber Facility to evaluate evaporative cooling behavior patterns in a turbine as a function of the quantity of water trapped in the turbine and as a function of the vehicle ascent pressure profile. It was found that evaporative freezing of water in the turbine housing, due to rapid depressurization within the turbine during vehicle ascent, could result in the formation of ice that would block the turbine and prevent rotation of the boost pump. But for such icing conditions to exist it would be necessary to have significant quantities of water in the turbine and/or its components, and the turbine housing temperature would have to be colder than 40 F at vehicle liftoff.

ASTRONOMY: Neighborhood Gamma Ray Burst Boosts Theory.

PubMed

Schilling, G

2000-07-07

Titanic explosions that emit powerful flashes of energetic gamma rays are one of astronomy's hottest mysteries. Now an analysis of the nearest gamma ray burst yet detected has added weight to the popular theory that they are expelled during the death throes of supermassive stars.

Addressing Achievement Gaps with Psychological Interventions

ERIC Educational Resources Information Center

Yeager, David; Walton, Gregory; Cohen, Geoffrey L.

2013-01-01

Student psychology--how the classroom looks and feels from the perspective of the student--can powerfully affect motivation and learning, and experiments are increasingly showing that even brief interventions to change psychology can boost achievement over months or years. When paired with other structural reforms, social-psychological…

Bidirectional buck boost converter

DOEpatents

Esser, Albert Andreas Maria

1998-03-31

A bidirectional buck boost converter and method of operating the same allows regulation of power flow between first and second voltage sources in which the voltage level at each source is subject to change and power flow is independent of relative voltage levels. In one embodiment, the converter is designed for hard switching while another embodiment implements soft switching of the switching devices. In both embodiments, first and second switching devices are serially coupled between a relatively positive terminal and a relatively negative terminal of a first voltage source with third and fourth switching devices serially coupled between a relatively positive terminal and a relatively negative terminal of a second voltage source. A free-wheeling diode is coupled, respectively, in parallel opposition with respective ones of the switching devices. An inductor is coupled between a junction of the first and second switching devices and a junction of the third and fourth switching devices. Gating pulses supplied by a gating circuit selectively enable operation of the switching devices for transferring power between the voltage sources. In the second embodiment, each switching device is shunted by a capacitor and the switching devices are operated when voltage across the device is substantially zero.

Bidirectional buck boost converter

DOEpatents

Esser, A.A.M.

1998-03-31

A bidirectional buck boost converter and method of operating the same allows regulation of power flow between first and second voltage sources in which the voltage level at each source is subject to change and power flow is independent of relative voltage levels. In one embodiment, the converter is designed for hard switching while another embodiment implements soft switching of the switching devices. In both embodiments, first and second switching devices are serially coupled between a relatively positive terminal and a relatively negative terminal of a first voltage source with third and fourth switching devices serially coupled between a relatively positive terminal and a relatively negative terminal of a second voltage source. A free-wheeling diode is coupled, respectively, in parallel opposition with respective ones of the switching devices. An inductor is coupled between a junction of the first and second switching devices and a junction of the third and fourth switching devices. Gating pulses supplied by a gating circuit selectively enable operation of the switching devices for transferring power between the voltage sources. In the second embodiment, each switching device is shunted by a capacitor and the switching devices are operated when voltage across the device is substantially zero. 20 figs.

PSO Based PI Controller Design for a Solar Charger System

PubMed Central

Yau, Her-Terng; Lin, Chih-Jer; Liang, Qin-Cheng

2013-01-01

Due to global energy crisis and severe environmental pollution, the photovoltaic (PV) system has become one of the most important renewable energy sources. Many previous studies on solar charger integrated system only focus on load charge control or switching Maximum Power Point Tracking (MPPT) and charge control modes. This study used two-stage system, which allows the overall portable solar energy charging system to implement MPPT and optimal charge control of Li-ion battery simultaneously. First, this study designs a DC/DC boost converter of solar power generation, which uses variable step size incremental conductance method (VSINC) to enable the solar cell to track the maximum power point at any time. The voltage was exported from the DC/DC boost converter to the DC/DC buck converter, so that the voltage dropped to proper voltage for charging the battery. The charging system uses constant current/constant voltage (CC/CV) method to charge the lithium battery. In order to obtain the optimum PI charge controller parameters, this study used intelligent algorithm to determine the optimum parameters. According to the simulation and experimental results, the control parameters resulted from PSO have better performance than genetic algorithms (GAs). PMID:23766713

PSO based PI controller design for a solar charger system.

PubMed

Yau, Her-Terng; Lin, Chih-Jer; Liang, Qin-Cheng

2013-01-01

Due to global energy crisis and severe environmental pollution, the photovoltaic (PV) system has become one of the most important renewable energy sources. Many previous studies on solar charger integrated system only focus on load charge control or switching Maximum Power Point Tracking (MPPT) and charge control modes. This study used two-stage system, which allows the overall portable solar energy charging system to implement MPPT and optimal charge control of Li-ion battery simultaneously. First, this study designs a DC/DC boost converter of solar power generation, which uses variable step size incremental conductance method (VSINC) to enable the solar cell to track the maximum power point at any time. The voltage was exported from the DC/DC boost converter to the DC/DC buck converter, so that the voltage dropped to proper voltage for charging the battery. The charging system uses constant current/constant voltage (CC/CV) method to charge the lithium battery. In order to obtain the optimum PI charge controller parameters, this study used intelligent algorithm to determine the optimum parameters. According to the simulation and experimental results, the control parameters resulted from PSO have better performance than genetic algorithms (GAs).

A Laser Cavity for a Future Photon Collider at ILC

NASA Astrophysics Data System (ADS)

Klemz, G.; Moenig, K.

2006-04-01

Within a future photon-collider based on the infrastructure of ILC the energy of near-infrared laser photons will be boosted by Compton backscattering on a high energy electron beam to well above 100 GeV. By reason of luminosity, an extremely powerful lasersystem is required that will exceed today's state-of-the-art capabilities. An auxiliary cavity for resonantly enhancing the optical peak-power can relax demands on the power output of the laser. In this paper a possible design and the static aspects of a passive cavity are discussed.

A Fully Directional Universal Power Electronic Interface for EV, HEV, and PHEV Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Onar, Omer C

2012-01-01

This study focuses on a universal power electronic interface that can be utilized in any type of the electric vehicles, hybrid electric vehicles, and plug-in hybrid electric vehicles (PHEVs). Basically, the proposed converter interfaces the energy storage device of the vehicle with the motor drive and the external charger, in case of PHEVs. The proposed converter is capable of operating in all directions in buck or boost modes with a noninverted output voltage (positive output voltage with respect to the input) and bidirectional power flow.

Centaur feedline dynamics study using power spectral methods. [fundamental mode resonant frequencies of RL-10 oxygen and hydrogen feed lines

NASA Technical Reports Server (NTRS)

Lorenzo, C. F.

1974-01-01

Tests were conducted to determine the dynamic characteristics of the Centaur/RL-10 oxygen and hydrogen feedlines. The fundamental-mode resonant frequencies were determined by applying power spectral methods to noise-generated data from hot firings of the RL-10 engine. The effect of net positive suction pressure of the main feed pumps on resonant frequency characteristics was determined to be a straight-line relation. Power spectral methods were also used to determine the dynamic characteristics of the boost pumps.

Decorrelated jet substructure tagging using adversarial neural networks

NASA Astrophysics Data System (ADS)

Shimmin, Chase; Sadowski, Peter; Baldi, Pierre; Weik, Edison; Whiteson, Daniel; Goul, Edward; Søgaard, Andreas

2017-10-01

We describe a strategy for constructing a neural network jet substructure tagger which powerfully discriminates boosted decay signals while remaining largely uncorrelated with the jet mass. This reduces the impact of systematic uncertainties in background modeling while enhancing signal purity, resulting in improved discovery significance relative to existing taggers. The network is trained using an adversarial strategy, resulting in a tagger that learns to balance classification accuracy with decorrelation. As a benchmark scenario, we consider the case where large-radius jets originating from a boosted resonance decay are discriminated from a background of nonresonant quark and gluon jets. We show that in the presence of systematic uncertainties on the background rate, our adversarially trained, decorrelated tagger considerably outperforms a conventionally trained neural network, despite having a slightly worse signal-background separation power. We generalize the adversarial training technique to include a parametric dependence on the signal hypothesis, training a single network that provides optimized, interpolatable decorrelated jet tagging across a continuous range of hypothetical resonance masses, after training on discrete choices of the signal mass.

Silicon-Carbide Power MOSFET Performance in High Efficiency Boost Power Processing Unit for Extreme Environments

NASA Technical Reports Server (NTRS)

Ikpe, Stanley A.; Lauenstein, Jean-Marie; Carr, Gregory A.; Hunter, Don; Ludwig, Lawrence L.; Wood, William; Del Castillo, Linda Y.; Fitzpatrick, Fred; Chen, Yuan

2016-01-01

Silicon-Carbide device technology has generated much interest in recent years. With superior thermal performance, power ratings and potential switching frequencies over its Silicon counterpart, Silicon-Carbide offers a greater possibility for high powered switching applications in extreme environment. In particular, Silicon-Carbide Metal-Oxide- Semiconductor Field-Effect Transistors' (MOSFETs) maturing process technology has produced a plethora of commercially available power dense, low on-state resistance devices capable of switching at high frequencies. A novel hard-switched power processing unit (PPU) is implemented utilizing Silicon-Carbide power devices. Accelerated life data is captured and assessed in conjunction with a damage accumulation model of gate oxide and drain-source junction lifetime to evaluate potential system performance at high temperature environments.

A planning comparison of 7 irradiation options allowed in RTOG 1005 for early-stage breast cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Guang-Pei, E-mail: gpchen@mcw.edu; Liu, Feng; White, Julia

2015-04-01

This study compared the 7 treatment plan options in achieving the dose-volume criteria required by the Radiation Therapy Oncology Group (RTOG) 1005 protocol. Dosimetry plans were generated for 15 representative patients with early-stage breast cancer (ESBC) based on the protocol-required dose-volume criteria for each of the following 7 treatment options: 3D conformal radiotherapy (3DCRT), whole-breast irradiation (WBI) plus 3DCRT lumpectomy boost, 3DCRT WBI plus electron boost, 3DCRT WBI plus intensity-modulated radiation therapy (IMRT) boost, IMRT WBI plus 3DCRT boost, IMRT WBI plus electron boost, IMRT WBI plus IMRT boost, and simultaneous integrated boost (SIB) with IMRT. A variety of dose-volumemore » parameters, including target dose conformity and uniformity and normal tissue sparing, were compared for these plans. For the patients studied, all plans met the required acceptable dose-volume criteria, with most of them meeting the ideal criteria. When averaged over patients, most dose-volume goals for all plan options can be achieved with a positive gap of at least a few tenths of standard deviations. The plans for all 7 options are generally comparable. The dose-volume goals required by the protocol can in general be easily achieved. IMRT WBI provides better whole-breast dose uniformity than 3DCRT WBI does, but it causes no significant difference for the dose conformity. All plan options are comparable for lumpectomy dose uniformity and conformity. Patient anatomy is always an important factor when whole-breast dose uniformity and conformity and lumpectomy dose conformity are considered.« less

Research requirements for emergency power to permit hover-one-engine-inoperative helicopter operation

NASA Technical Reports Server (NTRS)

Yost, J. H.

1976-01-01

The research and technology demonstration requirements to achieve emergency-power capability for a civil helicopter are documented. The goal for emergency power is the ability to hover with one engine inoperative, transition to minimum-power forward flight, and continue to a safe landing where emergency power may or may not be required. The best method to obtain emergency power is to augment the basic engine power by increasing the engine's speed and turbine-inlet temperature, combined with water-alcohol injection at the engine inlet. Other methods, including turbine boost power and flywheel energy, offer potential for obtaining emergency power for minimum time durations. Costs and schedules are estimated for a research and development program to bring emergency power through a hardware-demonstration test. Interaction of engine emergency-power capability with other helicopter systems is examined.

Learning and Parallelization Boost Constraint Search

ERIC Educational Resources Information Center

Yun, Xi

2013-01-01

Constraint satisfaction problems are a powerful way to abstract and represent academic and real-world problems from both artificial intelligence and operations research. A constraint satisfaction problem is typically addressed by a sequential constraint solver running on a single processor. Rather than construct a new, parallel solver, this work…

PubMed

1988-06-04

Fourth year student nurse tmma Moore accepts a high-powered boost to the Great Ormond Street Wishing Well Appeal. The new Escort donated by Ford Motor Company Limited will be raffled by the Hospital's nurses during their rag week in August. Proceeds from the raffle will be added to the £25 million appeal fund.

New approaches to provide ride-through for critical loads in electric power distribution systems

NASA Astrophysics Data System (ADS)

Montero-Hernandez, Oscar C.

2001-07-01

The extensive use of electronic circuits has enabled modernization, automation, miniaturization, high quality, low cost, and other achievements regarding electric loads in the last decades. However, modern electronic circuits and systems are extremely sensitive to disturbances from the electric power supply. In fact, the rate at which these disturbances happen is considerable as has been documented in recent years. In response to the power quality concerns presented previously, this dissertation is proposing new approaches to provide ride-through for critical loads during voltage disturbances with emphasis on voltage sags. In this dissertation, a new approach based on an AC-DC-AC system is proposed to provide ride-through for critical loads connected in buildings and/or an industrial system. In this approach, a three-phase IGBT inverter with a built in Dc-link voltage regulator is suitably controlled along with static by-pass switches to provide continuous power to critical loads. During a disturbance, the input utility source is disconnected and the power from the inverter is connected to the load. The remaining voltage in the AC supply is converted to DC and compensated before being applied to the inverter and the load. After detecting normal utility conditions, power from the utility is restored to the critical load. In order to achieve an extended ride-through capability a second approach is introduced. In this case, the Dc-link voltage regulator is performed by a DC-DC Buck-Boost converter. This new approach has the capability to mitigate voltage variations below and above the nominal value. In the third approach presented in this dissertation, a three-phase AC to AC boost converter is investigated. This converter provides a boosting action for the utility input voltages, right before they are applied to the load. The proposed Pulse Width Modulation (PWM) control strategy ensures independent control of each phase and compensates for both single-phase or poly-phase voltage sags. Algorithms capable of detecting voltage disturbances such as voltage sags, voltage swells, flicker, frequency change, and harmonics in a fast and reliable way are investigated and developed in this dissertation as an essential part of the approaches previously described. Simulation and experimental work has been done to validate the feasibility of all approaches under the most common voltage disturbances such as single-phase voltage sags and three-phase voltage sags.

Enhanced power factor via the control of structural phase transition in SnSe

PubMed Central

Yu, Hulei; Dai, Shuai; Chen, Yue

2016-01-01

Tin selenide has attracted much research interest due to its unprecedentedly high thermoelectric figure of merit (ZT). For real applications, it is desirable to increase the ZT value in the lower-temperature range, as the peak ZT value currently exists near the melting point. It is shown in this paper that the structural phase transition plays an important role in boosting the ZT value of SnSe in the lower-temperature range, as the Cmcm phase is found to have a much higher power factor than the Pnma phase. Furthermore, hydrostatic pressure is predicted to be extremely effective in tuning the phase transition temperature based on ab-initio molecular dynamic simulations; a remarkable decrease in the phase transition temperature is found when a hydrostatic pressure is applied. Dynamical stabilities are investigated based on phonon calculations, providing deeper insight into the pressure effects. Accurate band structures are obtained using the modified Becke-Johnson correction, allowing reliable prediction of the electrical transport properties. The effects of hydrostatic pressure on the thermal transport properties are also discussed. Hydrostatic pressure is shown to be efficient in manipulating the transport properties via the control of phase transition temperature in SnSe, paving a new path for enhancing its thermoelectric efficiency. PMID:27193260

Design of A Grid Integrated PV System with MPPT Control and Voltage Oriented Controller using MATLAB/PLECES

NASA Astrophysics Data System (ADS)

Soreng, Bineeta; Behera, Pradyumna; Pradhan, Raseswari

2017-08-01

This paper presents model of a grid-integrated photovoltaic array with Maximum Power Point Tracker (MPPT) and voltage oriented controller. The MPPT of the PV array is usually an essential part of PV system as MPPT helps the operating point of the solar array to align its maximum power point. In this model, the MPPT along with a DC-DC converter lets a PV generator to produce continuous power, despite of the measurement conditions. The neutral-point-clamped converter (NPC) with a boost converter raises the voltage from the panels to the DC-link. An LCL-filter smoothens the current ripple caused by the PWM modulation of the grid-side inverter. In addition to the MPPT, the system has two more two controllers, such as voltage controller and a current controller. The voltage control has a PI controller to regulate the PV voltage to optimal level by controlling the amount of current injected into the boost stage. Here, the grid-side converter transfers the power from the DC-link into the grid and maintains the DC-link voltage. Three-phase PV inverters are used for off-grid or designed to create utility frequency AC. The PV system can be connected in series or parallel to get the desired output power. To justify the working of this model, the grid-integrated PV system has been designed in MATLAB/PLECS. The simulation shows the P-V curve of implemented PV Array consisting 4 X 20 modules, reactive, real power, grid voltage and current.

Clinical radiobiology of stage T2-T3 bladder cancer.

PubMed

Majewski, Wojciech; Maciejewski, Boguslaw; Majewski, Stanislaw; Suwinski, Rafal; Miszczyk, Leszek; Tarnawski, Rafal

2004-09-01

To evaluate the relationship between total radiation dose and overall treatment time (OTT) with the treatment outcome, with adjustment for selected clinical factors, in patients with Stage T2-T3 bladder cancer treated with curative radiotherapy (RT). The analysis was based on 480 patients with Stage T2-T3 bladder cancer who were treated at the Center of Oncology in Gliwice between 1975 and 1995. The mean total radiation dose was 65.5 Gy, and the mean OTT was 51 days. In 261 patients (54%), planned and unplanned gaps occurred during RT. Four fractionation schedules were used: (1) conventional fractionation (once daily, 1.8-2.5 Gy/fraction); (2) protracted fractionation (pelvic RT, once daily, 1.6-1.7 Gy/fraction, boost RT, once daily, 2.0 Gy/fraction); (3) accelerated hyperfractionated boost (pelvic RT, once daily, 2.0 Gy/fraction; boost RT, twice daily, 1.3-1.4 Gy/fraction); and (4) accelerated hyperfractionation (pelvic and boost RT, twice daily, 1.2-1.5 Gy/fraction). In all fractionation schedules, the total radiation dose was similar (average 65.5 Gy), but the OTT was different (mean 53 days for conventional fractionation, 62 days for protracted fractionation, 45 days for accelerated hyperfractionated boost, and 41 days for accelerated hyperfractionation). A Cox proportional hazard model and maximum likelihood logistic model were used to evaluate the relationship between the treatment-related parameters (total radiation dose, dose per fraction, and OTT) and clinical factors (clinical T stage, hemoglobin level and bladder capacity before RT) and treatment outcome. With a median follow-up of 76 months, the actuarial 5-year local control rate was 47%, and the overall survival rate was 40%. The logistic analysis, which included the total dose, OTT, and T stage, revealed that all of these factors were significantly related to tumor control probability (p = 0.021 for total radiation dose, p = 0.038 for OTT, and p = 0.00068 for T stage). A multivariate Cox model, which included the treatment-related parameters and other clinical factors, revealed that the hemoglobin level and bladder capacity before RT and T-stage were statistically significant factors determining local control and overall survival. The total radiation dose was of borderline statistical significance for overall survival (p = 0.087), and OTT did not reach statistical significance. The results of our study showed that the treatment outcome after RT for bladder cancer depends mainly on clinical factors: hemoglobin level and bladder capacity before RT, and clinical T stage. An increase in the total radiation dose seemed to be associated with a better treatment outcome. The effect of the OTT was difficult to define, because it was influenced by other prognostic factors.

Modeling and control of fuel cell based distributed generation systems

NASA Astrophysics Data System (ADS)

Jung, Jin Woo

This dissertation presents circuit models and control algorithms of fuel cell based distributed generation systems (DGS) for two DGS topologies. In the first topology, each DGS unit utilizes a battery in parallel to the fuel cell in a standalone AC power plant and a grid-interconnection. In the second topology, a Z-source converter, which employs both the L and C passive components and shoot-through zero vectors instead of the conventional DC/DC boost power converter in order to step up the DC-link voltage, is adopted for a standalone AC power supply. In Topology 1, two applications are studied: a standalone power generation (Single DGS Unit and Two DGS Units) and a grid-interconnection. First, dynamic model of the fuel cell is given based on electrochemical process. Second, two full-bridge DC to DC converters are adopted and their controllers are designed: an unidirectional full-bridge DC to DC boost converter for the fuel cell and a bidirectional full-bridge DC to DC buck/boost converter for the battery. Third, for a three-phase DC to AC inverter without or with a Delta/Y transformer, a discrete-time state space circuit model is given and two discrete-time feedback controllers are designed: voltage controller in the outer loop and current controller in the inner loop. And last, for load sharing of two DGS units and power flow control of two DGS units or the DGS connected to the grid, real and reactive power controllers are proposed. Particularly, for the grid-connected DGS application, a synchronization issue between an islanding mode and a paralleling mode to the grid is investigated, and two case studies are performed. To demonstrate the proposed circuit models and control strategies, simulation test-beds using Matlab/Simulink are constructed for each configuration of the fuel cell based DGS with a three-phase AC 120 V (L-N)/60 Hz/50 kVA and various simulation results are presented. In Topology 2, this dissertation presents system modeling, modified space vector PWM implementation (MSVPWM) and design of a closed-loop controller of the Z-source converter which utilizes L and C components and shoot-through zero vectors for the standalone AC power generation. The fuel cell system is modeled by an electrical R-C circuit in order to include slow dynamics of the fuel cells and a voltage-current characteristic of a cell is also considered. A discrete-time state space model is derived to implement digital control and a space vector pulse-width modulation (SVPWM) technique is modified to realize the shoot-through zero vectors that boost the DC-link voltage. Also, three discrete-time feedback controllers are designed: a discrete-time optimal voltage controller, a discrete-time sliding mode current controller, and a discrete-time PI DC-link voltage controller. Furthermore, an asymptotic observer is used to reduce the number of sensors and enhance the reliability of the system. To demonstrate the analyzed circuit model and proposed control strategy, various simulation results using Matlab/Simulink are presented under both light/heavy loads and linear/nonlinear loads for a three-phase AC 208 V (L-L)/60 Hz/10 kVA.

Boosting the optical performance and commutation speed of phototransistor using SiGe/Si/Ge tunneling structure

NASA Astrophysics Data System (ADS)

Ferhati, H.; Djeffal, F.

2018-06-01

In this paper, a new optically controlled tunneling field effect transistor (OC-TFET) based on SiGe/Si/Ge hetero-channel is proposed to improve optical commutation speed and reduce power consumption. An exhaustive study of the device switching behavior associated with different hetero-channel structures has been carried out using an accurate numerical simulation. Moreover, a new figure of Merit (FoM) parameter called optical swing factor that describes the phototransistor optical commutation speed is proposed. We demonstrate that the band-to-band tunneling effect can be beneficial for improving the device optical commutation speed. The impact of the Ge mole fraction of the SiGe source region on the device FoMs is investigated. It is found that the optimized design with 40% of Ge content offers the opportunity to overcome the trade-off between ultrafast and very sensitive photoreceiver performance, where it yields 48 mV/dec of optical swing factor and 155 dB of I ON /I OFF ratio. An overall performance comparison between the proposed OC-TFET device and the conventional designs is performed, where the proposed structure ensures high optical detectivity for very low optical powers (sub-1pW) as compared to that of the conventional counterparts. Therefore, the proposed OC-TFET provides the possibility for bridging the gap between improved optical commutation speed and reduced power consumption, which makes it a potential alternative for high-performance inter-chip data communication applications.

Coal gasification power plant and process

DOEpatents

Woodmansee, Donald E.

1979-01-01

In an integrated coal gasification power plant, a humidifier is provided for transferring as vapor, from the aqueous blowdown liquid into relatively dry air, both (I) at least a portion of the water contained in the aqueous liquid and (II) at least a portion of the volatile hydrocarbons therein. The resulting humidified air is advantageously employed as at least a portion of the hot air and water vapor included in the blast gas supplied via a boost compressor to the gasifier.

In Situ High-Level Nitrogen Doping into Carbon Nanospheres and Boosting of Capacitive Charge Storage in Both Anode and Cathode for a High-Energy 4.5 V Full-Carbon Lithium-Ion Capacitor.

PubMed

Sun, Fei; Liu, Xiaoyan; Wu, Hao Bin; Wang, Lijie; Gao, Jihui; Li, Hexing; Lu, Yunfeng

2018-05-02

To circumvent the imbalances of electrochemical kinetics and capacity between Li + storage anodes and capacitive cathodes for lithium-ion capacitors (LICs), we herein demonstrate an efficient solution by boosting the capacitive charge-storage contributions of carbon electrodes to construct a high-performance LIC. Such a strategy is achieved by the in situ and high-level doping of nitrogen atoms into carbon nanospheres (ANCS), which increases the carbon defects and active sites, inducing more rapidly capacitive charge-storage contributions for both Li + storage anodes and PF 6 - storage cathodes. High-level nitrogen-doping-induced capacitive enhancement is successfully evidenced by the construction of a symmetric supercapacitor using commercial organic electrolytes. Coupling a pre-lithiated ANCS anode with a fresh ANCS cathode enables a full-carbon LIC with a high operating voltage of 4.5 V and high energy and power densities thereof. The assembled LIC device delivers high energy densities of 206.7 and 115.4 Wh kg -1 at power densities of 0.225 and 22.5 kW kg -1 , respectively, as well as an unprecedented high-power cycling stability with only 0.0013% capacitance decay per cycle within 10 000 cycles at a high power output of 9 kW kg -1 .

Can Reflection Boost Competences Development in Organizations?

ERIC Educational Resources Information Center

Nansubuga, Florence; Munene, John C.; Ntayi, Joseph M.

2015-01-01

Purpose: The purpose of this paper is to examine the gaps in some existing competence frameworks and investigate the power of reflection on one's behavior to improve the process of the competences development. Design/methodology/approach: The authors used a correlational design and a quasi-experimental non-equivalent group design involving a…

Play: Ten Power Boosts for Children's Early Learning

ERIC Educational Resources Information Center

Honig, Alice

2007-01-01

Play is children's work. Alice Honig enumerates from the heart 10 ways in which children learn through play, including building dexterity; social skills; cognitive and language skills; number and time concepts; spatial understanding; reasoning of cause and effect; clarification of pretend versus real; sensory and aesthetic appreciation; extended…

Theoretical Framework for Educational Assessment: A Synoptic Review

ERIC Educational Resources Information Center

Ghaicha, Abdallah

2016-01-01

At this age of accountability, it is acknowledged that assessment is a powerful lever that can either boost or undermine students' learning. Hitherto, much of the regular institutional and instructional practices show that assessments remain inhibitory or void rather than constructive as these lack the assessment formative aspect. This denotes…

The Crucial Coaching Relationship

ERIC Educational Resources Information Center

Scales, Peter C.

2016-01-01

One of the most powerful ways to boost the payoff from school sports lays in helping coaches build developmental relationships with student-athletes. Developmental relationships are close connections through which young people develop character skills to discover who they are, gain the ability to shape their own lives, and learn how to interact…

The Power of Place: How Housing Policy Can Boost Educational Opportunity

ERIC Educational Resources Information Center

DeLuca, Stefanie; Rhodes, Anna; Garboden, Philip M. E.

2016-01-01

For decades, Baltimore's poorest African American children have been channeled into racially and economically segregated neighborhoods with low-performing schools. Financial constraints and scarce affordable housing in more affluent communities have made it very difficult for poor families to access higher quality educational opportunities for…

Research Technology

NASA Image and Video Library

2004-04-15

Harnessing the Sun's energy through Solar Thermal Propulsion will propel vehicles through space by significantly reducing weight, complexity, and cost while boosting performance over current conventional upper stages. Another solar powered system, solar electric propulsion, demonstrates ion propulsion is suitable for long duration missions. Pictured is an artist's concept of space flight using solar thermal propulsion.

77 FR 20505 - Airworthiness Directives; The Boeing Company Airplanes

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-05

... Company Model 757 airplanes. This AD requires replacing the power control relays for the fuel boost pumps and override pumps with new relays having a ground fault interrupter (GFI) feature. This AD also requires an electrical bonding resistance measurement for certain GFI relays to verify that certain bonding...

Does Student Attrition Explain KIPP's Success?

ERIC Educational Resources Information Center

Nichols-Barrer, Ira; Gill, Brian P.; Gleason, Philip; Tuttle, Christina Clark

2014-01-01

The Knowledge Is Power Program (KIPP) is a network of charter schools designed to improve the educational opportunities available to low-income families. KIPP schools seek to boost their students' academic achievement and ultimately prepare them to enroll and succeed in college. To achieve these objectives, KIPP schools leverage strong…

Factor complexity of crash occurrence: An empirical demonstration using boosted regression trees.

PubMed

Chung, Yi-Shih

2013-12-01

Factor complexity is a characteristic of traffic crashes. This paper proposes a novel method, namely boosted regression trees (BRT), to investigate the complex and nonlinear relationships in high-variance traffic crash data. The Taiwanese 2004-2005 single-vehicle motorcycle crash data are used to demonstrate the utility of BRT. Traditional logistic regression and classification and regression tree (CART) models are also used to compare their estimation results and external validities. Both the in-sample cross-validation and out-of-sample validation results show that an increase in tree complexity provides improved, although declining, classification performance, indicating a limited factor complexity of single-vehicle motorcycle crashes. The effects of crucial variables including geographical, time, and sociodemographic factors explain some fatal crashes. Relatively unique fatal crashes are better approximated by interactive terms, especially combinations of behavioral factors. BRT models generally provide improved transferability than conventional logistic regression and CART models. This study also discusses the implications of the results for devising safety policies. Copyright © 2012 Elsevier Ltd. All rights reserved.

A planning comparison of 7 irradiation options allowed in RTOG 1005 for early-stage breast cancer.

PubMed

Chen, Guang-Pei; Liu, Feng; White, Julia; Vicini, Frank A; Freedman, Gary M; Arthur, Douglas W; Li, X Allen

2015-01-01

This study compared the 7 treatment plan options in achieving the dose-volume criteria required by the Radiation Therapy Oncology Group (RTOG) 1005 protocol. Dosimetry plans were generated for 15 representative patients with early-stage breast cancer (ESBC) based on the protocol-required dose-volume criteria for each of the following 7 treatment options: 3D conformal radiotherapy (3DCRT), whole-breast irradiation (WBI) plus 3DCRT lumpectomy boost, 3DCRT WBI plus electron boost, 3DCRT WBI plus intensity-modulated radiation therapy (IMRT) boost, IMRT WBI plus 3DCRT boost, IMRT WBI plus electron boost, IMRT WBI plus IMRT boost, and simultaneous integrated boost (SIB) with IMRT. A variety of dose-volume parameters, including target dose conformity and uniformity and normal tissue sparing, were compared for these plans. For the patients studied, all plans met the required acceptable dose-volume criteria, with most of them meeting the ideal criteria. When averaged over patients, most dose-volume goals for all plan options can be achieved with a positive gap of at least a few tenths of standard deviations. The plans for all 7 options are generally comparable. The dose-volume goals required by the protocol can in general be easily achieved. IMRT WBI provides better whole-breast dose uniformity than 3DCRT WBI does, but it causes no significant difference for the dose conformity. All plan options are comparable for lumpectomy dose uniformity and conformity. Patient anatomy is always an important factor when whole-breast dose uniformity and conformity and lumpectomy dose conformity are considered. Copyright © 2015 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.

Mn-doped quantum dot sensitized solar cells: a strategy to boost efficiency over 5%.

PubMed

Santra, Pralay K; Kamat, Prashant V

2012-02-08

To make Quantum Dot Sensitized Solar Cells (QDSC) competitive, it is necessary to achieve power conversion efficiencies comparable to other emerging solar cell technologies. By employing Mn(2+) doping of CdS, we have now succeeded in significantly improving QDSC performance. QDSC constructed with Mn-doped-CdS/CdSe deposited on mesoscopic TiO(2) film as photoanode, Cu(2)S/Graphene Oxide composite electrode, and sulfide/polysulfide electrolyte deliver power conversion efficiency of 5.4%.

Comparison of Two Railgun Power Supply Architectures to Quantify the Energy Dissipated After the Projectile Leaves the Railgun

DTIC Science & Technology

2016-06-01

inch gun on impact [1]. The potential of the EM railgun renders the need to store dangerous explosives associated with the conventional warheads...leaves the gun . The simulation will outline some critical performance characteristics of a buck-boost power supply as compared to a thyristor-based...between the rails and from the projectile position along the length of the gun x [5]: 3 1 2 𔃻 2 2 w o

Derivation of linearized transfer functions for switching-mode regulations. Phase A: Current step-up and voltage step-up converters

NASA Technical Reports Server (NTRS)

Wong, R. C.; Owen, H. A., Jr.; Wilson, T. G.

1981-01-01

Small-signal models are derived for the power stage of the voltage step-up (boost) and the current step-up (buck) converters. The modeling covers operation in both the continuous-mmf mode and the discontinuous-mmf mode. The power stage in the regulated current step-up converter on board the Dynamics Explorer Satellite is used as an example to illustrate the procedures in obtaining the small-signal functions characterizing a regulated converter.

Maximum Power Point Tracking Control of Hydrokinetic Turbine and Low-speed High-Thrust Permanent Magnet Generator Design

DTIC Science & Technology

2012-01-01

Schematic of the generator and power converters built in PLECS ............. 26 Figure 3.12. Block diagram of the MPPT control built in Matlab/Simulink...validated by simulation results done in Matlab/Simulink R2010a and PLECS . Figure 3.9 shows the block diagram of the hydrokinetic system built in Matlab...rectifier, boost converter and battery model built in PLECS . The battery bank on the load side is simulated by a constant dc voltage source. 25

New method of calculating the power at altitude of aircraft engines equipped with superchargers on the basis of tests made under sea-level conditions

NASA Technical Reports Server (NTRS)

Sarracino, Marcello

1941-01-01

The present article deals with what is considered to be a simpler and more accurate method of determining, from the results of bench tests under approved rating conditions, the power at altitude of a supercharged aircraft engine, without application of correction formulas. The method of calculating the characteristics at altitude, of supercharged engines, based on the consumption of air, is a more satisfactory and accurate procedure, especially at low boost pressures.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bantema-Joppe, Enja J.; Schilstra, Cornelis; Bock, Geertruida H. de

Purpose: To evaluate toxicity and cosmetic outcome (CO) in breast cancer survivors treated with three-dimensional conformal radiotherapy with a hypofractionated, simultaneous integrated boost (3D-CRT-SIB) and to identify risk factors for toxicity, with special focus on the impact of age. Methods and Materials: Included were 940 consecutive disease-free patients treated for breast cancer (Stage 0-III) with 3D-CRT-SIB, after breast-conserving surgery, from 2005 to 2010. Physician-rated toxicity (Common Terminology Criteria for Adverse Events version 3.0) and CO were prospectively assessed during yearly follow-up, up to 5 years after radiotherapy. Multivariate logistic regression analyses using a bootstrapping method were performed. Results: At 3more » years, toxicity scores of 436 patients were available. Grade {>=}2 fibrosis in the boost area was observed in 8.5%, non-boost fibrosis in 49.4%, pain to the chest wall in 6.7%, and fair/poor CO in 39.7% of cases. Radiotherapy before chemotherapy was significantly associated with grade {>=}2 boost fibrosis at 3 years (odds ratio [OR] 2.8, 95% confidence interval [CI] 1.3-6.0). Non-boost fibrosis was associated with re-resection (OR 2.2, 95% CI 1.2-4.0) and larger tumors (OR 1.1, 95% CI 1.0-1.1). At 1 year, chest wall pain was significantly associated with high boost dosage (OR 2.1, 95% CI 1.2-3.7) and younger age (OR 0.4, 95% CI 0.2-0.7). A fair/poor CO was observed more often after re-resection (OR 4.5, 95% CI 2.4-8.5), after regional radiotherapy (OR 2.9, 95% CI 1.2-7.1), and in larger tumors (OR 1.1, 95% CI 1.0-1.1). Conclusions: Toxicity and CO are not impaired after 3D-CRT-SIB. Fibrosis was not significantly associated with radiotherapy parameters. Independent risk factors for fibrosis were chemotherapy after radiotherapy, re-resection, and larger tumor size. Re-resection was most predictive for worse CO. Age had an impact on chest wall pain occurrence.« less

Accelerating atomistic simulations through self-learning bond-boost hyperdynamics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perez, Danny; Voter, Arthur F

2008-01-01

By altering the potential energy landscape on which molecular dynamics are carried out, the hyperdynamics method of Voter enables one to significantly accelerate the simulation state-to-state dynamics of physical systems. While very powerful, successful application of the method entails solving the subtle problem of the parametrization of the so-called bias potential. In this study, we first clarify the constraints that must be obeyed by the bias potential and demonstrate that fast sampling of the biased landscape is key to the obtention of proper kinetics. We then propose an approach by which the bond boost potential of Miron and Fichthorn canmore » be safely parametrized based on data acquired in the course of a molecular dynamics simulation. Finally, we introduce a procedure, the Self-Learning Bond Boost method, in which the parametrization is step efficiently carried out on-the-fly for each new state that is visited during the simulation by safely ramping up the strength of the bias potential up to its optimal value. The stability and accuracy of the method are demonstrated.« less

Using Boosting Decision Trees in Gravitational Wave Searches triggered by Gamma-ray Bursts

NASA Astrophysics Data System (ADS)

Zuraw, Sarah; LIGO Collaboration

2015-04-01

The search for gravitational wave bursts requires the ability to distinguish weak signals from background detector noise. Gravitational wave bursts are characterized by their transient nature, making them particularly difficult to detect as they are similar to non-Gaussian noise fluctuations in the detector. The Boosted Decision Tree method is a powerful machine learning algorithm which uses Multivariate Analysis techniques to explore high-dimensional data sets in order to distinguish between gravitational wave signal and background detector noise. It does so by training with known noise events and simulated gravitational wave events. The method is tested using waveform models and compared with the performance of the standard gravitational wave burst search pipeline for Gamma-ray Bursts. It is shown that the method is able to effectively distinguish between signal and background events under a variety of conditions and over multiple Gamma-ray Burst events. This example demonstrates the usefulness and robustness of the Boosted Decision Tree and Multivariate Analysis techniques as a detection method for gravitational wave bursts. LIGO, UMass, PREP, NEGAP.

Modeling evolution of dark matter substructure and annihilation boost

NASA Astrophysics Data System (ADS)

Hiroshima, Nagisa; Ando, Shin'ichiro; Ishiyama, Tomoaki

2018-06-01

We study evolution of dark matter substructures, especially how they lose mass and change density profile after they fall in gravitational potential of larger host halos. We develop an analytical prescription that models the subhalo mass evolution and calibrate it to results of N -body numerical simulations of various scales from very small (Earth size) to large (galaxies to clusters) halos. We then combine the results with halo accretion histories and calculate the subhalo mass function that is physically motivated down to Earth-mass scales. Our results—valid for arbitrary host masses and redshifts—have reasonable agreement with those of numerical simulations at resolved scales. Our analytical model also enables self-consistent calculations of the boost factor of dark matter annihilation, which we find to increase from tens of percent at the smallest (Earth) and intermediate (dwarfs) masses to a factor of several at galaxy size, and to become as large as a factor of ˜10 for the largest halos (clusters) at small redshifts. Our analytical approach can accommodate substructures in the subhalos (sub-subhalos) in a consistent framework, which we find to give up to a factor of a few enhancements to the annihilation boost. The presence of the subhalos enhances the intensity of the isotropic gamma-ray background by a factor of a few, and as the result, the measurement by the Fermi Large Area Telescope excludes the annihilation cross section greater than ˜4 ×10-26 cm3 s-1 for dark matter masses up to ˜200 GeV .

Design of an RF System for Electron Bernstein Wave Studies in MST

NASA Astrophysics Data System (ADS)

Kauffold, J. X.; Seltzman, A. H.; Anderson, J. K.; Nonn, P. D.; Forest, C. B.

2010-11-01

Motivated by the possibility of current profile control a 5.5GHz RF system for EBW is being developed. The central component is a standard radar Klystron with 1.2MW peak power and 4μs typical pulse length. Meaningful experiments require RF pulse lengths similar to the characteristic electron confinement times in MST necessitating the creation of a power supply providing 80kV at 40A for 10ms. A low inductance IGBT network switches power at 20kHz from an electrolytic capacitor bank into the primary of a three-phase resonant transformer system that is then rectified and filtered. The system uses three magnetically separate transformers with microcrystalline iron cores to provide suitable volt-seconds and low hysteresis losses. Each phase has a secondary with a large leakage inductance and a parallel capacitor providing a boost ratio greater than 60:1 with a physical turns ratio of 13.5:1. A microprocessor feedback control system varies the drive frequency around resonance to regulate the boost ratio and provide a stable output as the storage bank discharges. The completed system will deliver RF to the plasma boundary where coupling to the Bernstein mode and subsequent heating and current drive can occur.

Fuel cells, batteries and super-capacitors stand-alone power systems management using optimal/flatness based-control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Benaouadj, M.; Aboubou, A.; Bahri, M.

2016-07-25

In this work, an optimal control (under constraints) based on the Pontryagin’s maximum principle is used to optimally manage energy flows in a basic PEM (Proton Exchange Membrane) fuel cells system associated to lithium-ion batteries and supercapacitors through a common DC bus having a voltage to stabilize using the differential flatness approach. The adaptation of voltage levels between different sources and load is ensured by use of three DC-DC converters, one boost connected to the PEM fuel cells, while the two others are buck/boost and connected to the lithiumion batteries and supercapacitors. The aim of this paper is to developmore » an energy management strategy that is able to satisfy the following objectives: Impose the power requested by a habitat (representing the load) according to a proposed daily consumption profile, Keep fuel cells working at optimal power delivery conditions, Maintain constant voltage across the common DC bus, Stabilize the batteries voltage and stored quantity of charge at desired values given by the optimal control. Results obtained under MATLAB/Simulink environment prove that the cited objectives are satisfied, validating then, effectiveness and complementarity between the optimal and flatness concepts proposed for energy management. Note that this study is currently in experimentally validation within MSE Laboratory.« less

New angles on energy correlation functions

DOE PAGES

Moult, Ian; Necib, Lina; Thaler, Jesse

2016-12-29

Jet substructure observables, designed to identify specific features within jets, play an essential role at the Large Hadron Collider (LHC), both for searching for signals beyond the Standard Model and for testing QCD in extreme phase space regions. In this paper, we systematically study the structure of infrared and collinear safe substructure observables, defining a generalization of the energy correlation functions to probe n-particle correlations within a jet. These generalized correlators provide a flexible basis for constructing new substructure observables optimized for specific purposes. Focusing on three major targets of the jet substructure community — boosted top tagging, boosted W/Z/Hmore » tagging, and quark/gluon discrimination — we use power-counting techniques to identify three new series of powerful discriminants: M i, N i, and U i. The Mi series is designed for use on groomed jets, providing a novel example of observables with improved discrimination power after the removal of soft radiation. The N i series behave parametrically like the N -subjettiness ratio observables, but are defined without respect to subjet axes, exhibiting improved behavior in the unresolved limit. Finally, the U i series improves quark/gluon discrimination by using higher-point correlators to simultaneously probe multiple emissions within a jet. Taken together, these observables broaden the scope for jet substructure studies at the LHC.« less

New angles on energy correlation functions

NASA Astrophysics Data System (ADS)

Moult, Ian; Necib, Lina; Thaler, Jesse

2016-12-01

Jet substructure observables, designed to identify specific features within jets, play an essential role at the Large Hadron Collider (LHC), both for searching for signals beyond the Standard Model and for testing QCD in extreme phase space regions. In this paper, we systematically study the structure of infrared and collinear safe substructure observables, defining a generalization of the energy correlation functions to probe n-particle correlations within a jet. These generalized correlators provide a flexible basis for constructing new substructure observables optimized for specific purposes. Focusing on three major targets of the jet substructure community — boosted top tagging, boosted W/Z/H tagging, and quark/gluon discrimination — we use power-counting techniques to identify three new series of powerful discriminants: M i , N i , and U i . The M i series is designed for use on groomed jets, providing a novel example of observables with improved discrimination power after the removal of soft radiation. The N i series behave parametrically like the N -subjettiness ratio observables, but are defined without respect to subjet axes, exhibiting improved behavior in the unresolved limit. Finally, the U i series improves quark/gluon discrimination by using higher-point correlators to simultaneously probe multiple emissions within a jet. Taken together, these observables broaden the scope for jet substructure studies at the LHC.

Emulating DC constant power load: a robust sliding mode control approach

NASA Astrophysics Data System (ADS)

Singh, Suresh; Fulwani, Deepak; Kumar, Vinod

2017-09-01

This article presents emulation of a programmable power electronic, constant power load (CPL) using a dc/dc step-up (boost) converter. The converter is controlled by a robust sliding mode controller (SMC). A novel switching surface is proposed to ensure a required power sunk by the converter. The proposed dc CPL is simple in design, has fast dynamic response and high accuracy, and offers an inexpensive alternative to study converters for cascaded dc distribution power system applications. Furthermore, the proposed CPL is sufficiently robust against the input voltage variations. A laboratory prototype of the proposed dc CPL has been developed and validated with SMC realised through OPAL-RT platform. The capability of the proposed dc CPL is confirmed via experimentations in varied scenarios.

High-speed and low-power repeater for VLSI interconnects

NASA Astrophysics Data System (ADS)

Karthikeyan, A.; Mallick, P. S.

2017-10-01

This paper proposes a repeater for boosting the speed of interconnects with low power dissipation. We have designed and implemented at 45 and 32 nm technology nodes. Delay and power dissipation performances are analyzed for various voltage levels at these technology nodes using Spice simulations. A significant reduction in delay and power dissipation are observed compared to a conventional repeater. The results show that the proposed high-speed low-power repeater has a reduced delay for higher load capacitance. The proposed repeater is also compared with LPTG CMOS repeater, and the results shows that the proposed repeater has reduced delay. The proposed repeater can be suitable for high-speed global interconnects and has the capacity to drive large loads.

Changes in the TRMM Version-5 and Version-6 Precipitation Radar Products Due to Orbit Boost

NASA Technical Reports Server (NTRS)

Liao, Liang; Meneghini, Robert

2010-01-01

The performance of the version-5 and version-6 Tropical Rainfall Measuring Mission (TRMM) Precipitation Radar (PR) products before and after the satellite orbit boost is assessed through a series of comparisons with Weather Surveillance Radar (WSR)-88D ground-based radar in Melbourne, Florida. Analysis of the comparisons of radar reflectivity near the storm top from the ground radar and both versions of the PR indicates that the PR bias relative to the WSR radar at Melbourne is on the order of 1dB for both pre- and post-boost periods, indicating that the PR products maintain accurate calibration after the orbit boost. Comparisons with the WSR-88D near-surface reflectivity factors indicate that both versions of the PR products accurately correct for attenuation in stratiform rain. However, in convective rain, both versions exhibit negative biases in the near-surface radar reflectivity with version-6 products having larger negative biases than version-5. Rain rate comparisons between the ground and space radars show similar characteristics

Evaluating architecture impact on system energy efficiency

PubMed Central

Yu, Shijie; Wang, Rui; Luan, Zhongzhi; Qian, Depei

2017-01-01

As the energy consumption has been surging in an unsustainable way, it is important to understand the impact of existing architecture designs from energy efficiency perspective, which is especially valuable for High Performance Computing (HPC) and datacenter environment hosting tens of thousands of servers. One obstacle hindering the advance of comprehensive evaluation on energy efficiency is the deficient power measuring approach. Most of the energy study relies on either external power meters or power models, both of these two methods contain intrinsic drawbacks in their practical adoption and measuring accuracy. Fortunately, the advent of Intel Running Average Power Limit (RAPL) interfaces has promoted the power measurement ability into next level, with higher accuracy and finer time resolution. Therefore, we argue it is the exact time to conduct an in-depth evaluation of the existing architecture designs to understand their impact on system energy efficiency. In this paper, we leverage representative benchmark suites including serial and parallel workloads from diverse domains to evaluate the architecture features such as Non Uniform Memory Access (NUMA), Simultaneous Multithreading (SMT) and Turbo Boost. The energy is tracked at subcomponent level such as Central Processing Unit (CPU) cores, uncore components and Dynamic Random-Access Memory (DRAM) through exploiting the power measurement ability exposed by RAPL. The experiments reveal non-intuitive results: 1) the mismatch between local compute and remote memory node caused by NUMA effect not only generates dramatic power and energy surge but also deteriorates the energy efficiency significantly; 2) for multithreaded application such as the Princeton Application Repository for Shared-Memory Computers (PARSEC), most of the workloads benefit a notable increase of energy efficiency using SMT, with more than 40% decline in average power consumption; 3) Turbo Boost is effective to accelerate the workload execution and further preserve the energy, however it may not be applicable on system with tight power budget. PMID:29161317

Evaluating architecture impact on system energy efficiency.

PubMed

Yu, Shijie; Yang, Hailong; Wang, Rui; Luan, Zhongzhi; Qian, Depei

2017-01-01

As the energy consumption has been surging in an unsustainable way, it is important to understand the impact of existing architecture designs from energy efficiency perspective, which is especially valuable for High Performance Computing (HPC) and datacenter environment hosting tens of thousands of servers. One obstacle hindering the advance of comprehensive evaluation on energy efficiency is the deficient power measuring approach. Most of the energy study relies on either external power meters or power models, both of these two methods contain intrinsic drawbacks in their practical adoption and measuring accuracy. Fortunately, the advent of Intel Running Average Power Limit (RAPL) interfaces has promoted the power measurement ability into next level, with higher accuracy and finer time resolution. Therefore, we argue it is the exact time to conduct an in-depth evaluation of the existing architecture designs to understand their impact on system energy efficiency. In this paper, we leverage representative benchmark suites including serial and parallel workloads from diverse domains to evaluate the architecture features such as Non Uniform Memory Access (NUMA), Simultaneous Multithreading (SMT) and Turbo Boost. The energy is tracked at subcomponent level such as Central Processing Unit (CPU) cores, uncore components and Dynamic Random-Access Memory (DRAM) through exploiting the power measurement ability exposed by RAPL. The experiments reveal non-intuitive results: 1) the mismatch between local compute and remote memory node caused by NUMA effect not only generates dramatic power and energy surge but also deteriorates the energy efficiency significantly; 2) for multithreaded application such as the Princeton Application Repository for Shared-Memory Computers (PARSEC), most of the workloads benefit a notable increase of energy efficiency using SMT, with more than 40% decline in average power consumption; 3) Turbo Boost is effective to accelerate the workload execution and further preserve the energy, however it may not be applicable on system with tight power budget.

Solar Field Optical Characterization at Stillwater Geothermal/Solar Hybrid Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhu, Guangdong; Turchi, Craig

Concentrating solar power (CSP) can provide additional thermal energy to boost geothermal plant power generation. For a newly constructed solar field at a geothermal power plant site, it is critical to properly characterize its performance so that the prediction of thermal power generation can be derived to develop an optimum operating strategy for a hybrid system. In the past, laboratory characterization of a solar collector has often extended into the solar field performance model and has been used to predict the actual solar field performance, disregarding realistic impacting factors. In this work, an extensive measurement on mirror slope error andmore » receiver position error has been performed in the field by using the optical characterization tool called Distant Observer (DO). Combining a solar reflectance sampling procedure, a newly developed solar characterization program called FirstOPTIC and public software for annual performance modeling called System Advisor Model (SAM), a comprehensive solar field optical characterization has been conducted, thus allowing for an informed prediction of solar field annual performance. The paper illustrates this detailed solar field optical characterization procedure and demonstrates how the results help to quantify an appropriate tracking-correction strategy to improve solar field performance. In particular, it is found that an appropriate tracking-offset algorithm can improve the solar field performance by about 15%. The work here provides a valuable reference for the growing CSP industry.« less

Solar Field Optical Characterization at Stillwater Geothermal/Solar Hybrid Plant

DOE PAGES

Zhu, Guangdong; Turchi, Craig

2017-01-27

Concentrating solar power (CSP) can provide additional thermal energy to boost geothermal plant power generation. For a newly constructed solar field at a geothermal power plant site, it is critical to properly characterize its performance so that the prediction of thermal power generation can be derived to develop an optimum operating strategy for a hybrid system. In the past, laboratory characterization of a solar collector has often extended into the solar field performance model and has been used to predict the actual solar field performance, disregarding realistic impacting factors. In this work, an extensive measurement on mirror slope error andmore » receiver position error has been performed in the field by using the optical characterization tool called Distant Observer (DO). Combining a solar reflectance sampling procedure, a newly developed solar characterization program called FirstOPTIC and public software for annual performance modeling called System Advisor Model (SAM), a comprehensive solar field optical characterization has been conducted, thus allowing for an informed prediction of solar field annual performance. The paper illustrates this detailed solar field optical characterization procedure and demonstrates how the results help to quantify an appropriate tracking-correction strategy to improve solar field performance. In particular, it is found that an appropriate tracking-offset algorithm can improve the solar field performance by about 15%. The work here provides a valuable reference for the growing CSP industry.« less

Food Waste to Energy: How Six Water Resource Recovery Facilities are Boosting Biogas Production and the Bottom Line

EPA Science Inventory

Water Resource Recovery Facilities (WRRFs) with anaerobic digestion have been harnessing biogas for heat and power since at least the 1920’s. A few are approaching “energy neutrality” and some are becoming “energy positive” through a combination of energy efficiency measures and...

Fuzzy control of power converters based on quasilinear modelling

NASA Astrophysics Data System (ADS)

Li, C. K.; Lee, W. L.; Chou, Y. W.

1995-03-01

Unlike feedback control by the fuzzy PID method, a new fuzzy control algorithm based on quasilinear modelling of the DC-DC converter is proposed. Investigation is carried out using a buck-boost converter. Simulation results demonstrated that the converter can be regulated with improved performance even when subjected to input disturbance and load variation.

Boosting Your Baby's Brain Power

ERIC Educational Resources Information Center

Engel-Smothers, Holly; Heim, Susan M.

2009-01-01

With more than 100 billion neurons that would stretch more than 60,000 miles, a newborn baby's brain is quite phenomenal! These neurons must generally form connections within the first eight months of a baby's life to foster optimal brain growth and lifelong learning. Mommies, daddies, and caregivers are extremely vital to ensuring babies reach…

14 CFR 25.809 - Emergency exit arrangement.

Code of Federal Regulations, 2013 CFR

2013-01-01

...-boost or single power-operated system is the primary system for operating more than one exit in an... effort; and must be arranged and marked so that it can be readily located and operated, even in darkness... event of failure of the primary system. Manual operation of the exit (after failure of the primary...

14 CFR 25.809 - Emergency exit arrangement.

Code of Federal Regulations, 2012 CFR

2012-01-01

...-boost or single power-operated system is the primary system for operating more than one exit in an... effort; and must be arranged and marked so that it can be readily located and operated, even in darkness... event of failure of the primary system. Manual operation of the exit (after failure of the primary...

14 CFR 25.809 - Emergency exit arrangement.

Code of Federal Regulations, 2010 CFR

2010-01-01

...-boost or single power-operated system is the primary system for operating more than one exit in an... effort; and must be arranged and marked so that it can be readily located and operated, even in darkness... event of failure of the primary system. Manual operation of the exit (after failure of the primary...

14 CFR 25.809 - Emergency exit arrangement.

Code of Federal Regulations, 2014 CFR

2014-01-01

...-boost or single power-operated system is the primary system for operating more than one exit in an... effort; and must be arranged and marked so that it can be readily located and operated, even in darkness... event of failure of the primary system. Manual operation of the exit (after failure of the primary...

Solar Thermal Propulsion Concept

NASA Technical Reports Server (NTRS)

2004-01-01

Harnessing the Sun's energy through Solar Thermal Propulsion will propel vehicles through space by significantly reducing weight, complexity, and cost while boosting performance over current conventional upper stages. Another solar powered system, solar electric propulsion, demonstrates ion propulsion is suitable for long duration missions. Pictured is an artist's concept of space flight using solar thermal propulsion.

Modeling and Simulation: PowerBoosting Productivity with Simulation.

ERIC Educational Resources Information Center

Riley, Suzanne

Minnesota high school students and teachers are learning the technology of simulation and integrating it into business and industrial technology courses. Modeling and simulation is the science of using software to construct a system within an organization and then running simulations of proposed changes to assess results before funds are spent. In…

Lunar Soil Particle Separator

NASA Technical Reports Server (NTRS)

Berggren, Mark

2010-01-01

The Lunar Soil Particle Separator (LSPS) beneficiates soil prior to in situ resource utilization (ISRU). It can improve ISRU oxygen yield by boosting the concentration of ilmenite, or other iron-oxide-bearing materials found in lunar soils, which can substantially reduce hydrogen reduction reactor size, as well as drastically decreasing the power input required for soil heating

Development of CMOS Imager Block for Capsule Endoscope

NASA Astrophysics Data System (ADS)

Shafie, S.; Fodzi, F. A. M.; Tung, L. Q.; Lioe, D. X.; Halin, I. A.; Hasan, W. Z. W.; Jaafar, H.

2014-04-01

This paper presents the development of imager block to be associated in a capsule endoscopy system. Since the capsule endoscope is used to diagnose gastrointestinal diseases, the imager block must be in small size which is comfortable for the patients to swallow. In this project, a small size 1.5V button battery is used as the power supply while the voltage supply requirements for other components such as microcontroller and CMOS image sensor are higher. Therefore, a voltage booster circuit is proposed to boost up the voltage supply from 1.5V to 3.3V. A low power microcontroller is used to generate control pulses for the CMOS image sensor and to convert the 8-bits parallel data output to serial data to be transmitted to the display panel. The results show that the voltage booster circuit was able to boost the voltage supply from 1.5V to 3.3V. The microcontroller precisely controls the CMOS image sensor to produce parallel data which is then serialized again by the microcontroller. The serial data is then successfully translated to 2fps image and displayed on computer.

Efficient audio signal processing for embedded systems

NASA Astrophysics Data System (ADS)

Chiu, Leung Kin

As mobile platforms continue to pack on more computational power, electronics manufacturers start to differentiate their products by enhancing the audio features. However, consumers also demand smaller devices that could operate for longer time, hence imposing design constraints. In this research, we investigate two design strategies that would allow us to efficiently process audio signals on embedded systems such as mobile phones and portable electronics. In the first strategy, we exploit properties of the human auditory system to process audio signals. We designed a sound enhancement algorithm to make piezoelectric loudspeakers sound ”richer" and "fuller." Piezoelectric speakers have a small form factor but exhibit poor response in the low-frequency region. In the algorithm, we combine psychoacoustic bass extension and dynamic range compression to improve the perceived bass coming out from the tiny speakers. We also developed an audio energy reduction algorithm for loudspeaker power management. The perceptually transparent algorithm extends the battery life of mobile devices and prevents thermal damage in speakers. This method is similar to audio compression algorithms, which encode audio signals in such a ways that the compression artifacts are not easily perceivable. Instead of reducing the storage space, however, we suppress the audio contents that are below the hearing threshold, therefore reducing the signal energy. In the second strategy, we use low-power analog circuits to process the signal before digitizing it. We designed an analog front-end for sound detection and implemented it on a field programmable analog array (FPAA). The system is an example of an analog-to-information converter. The sound classifier front-end can be used in a wide range of applications because programmable floating-gate transistors are employed to store classifier weights. Moreover, we incorporated a feature selection algorithm to simplify the analog front-end. A machine learning algorithm AdaBoost is used to select the most relevant features for a particular sound detection application. In this classifier architecture, we combine simple "base" analog classifiers to form a strong one. We also designed the circuits to implement the AdaBoost-based analog classifier.

Dichroic subjettiness ratios to distinguish colour flows in boosted boson tagging

NASA Astrophysics Data System (ADS)

Salam, Gavin P.; Schunk, Lais; Soyez, Gregory

2017-03-01

N-subjettiness ratios are in wide use for tagging heavy boosted objects, in particular the ratio of 2-subjettiness to 1-subjettiness for tagging boosted electroweak bosons. In this article we introduce a new, dichroic ratio, which uses different regions of a jet to determine the two subjettiness measures, emphasising the hard substructure for the 1-subjettiness and the full colour radiation pattern for the 2-subjettiness. Relative to existing N -subjettiness ratios, the dichroic extension, combined with SoftDrop (pre-)grooming, makes it possible to increase the ultimate signal significance by about 25% (for 2 TeV jets), or to reduce non-perturbative effects by a factor of 2-3 at 50% signal efficiency while maintaining comparable background rejection. We motivate the dichroic approach through the study of Lund diagrams, supplemented with resummed analytical calculations.

Power management circuits for self-powered systems based on micro-scale solar energy harvesting

NASA Astrophysics Data System (ADS)

Yoon, Eun-Jung; Yu, Chong-Gun

2016-03-01

In this paper, two types of power management circuits for self-powered systems based on micro-scale solar energy harvesting are proposed. First, if a solar cell outputs a very low voltage, less than 0.5 V, as in miniature solar cells or monolithic integrated solar cells, such that it cannot directly power the load, a voltage booster is employed to step up the solar cell's output voltage, and then a power management unit (PMU) delivers the boosted voltage to the load. Second, if the output voltage of a solar cell is enough to drive the load, the PMU directly supplies the load with solar energy. The proposed power management systems are designed and fabricated in a 0.18-μm complementary metal-oxide-semiconductor process, and their performances are compared and analysed through measurements.

Modelling and simulation of two-chamber microbial fuel cell

NASA Astrophysics Data System (ADS)

Zeng, Yingzhi; Choo, Yeng Fung; Kim, Byung-Hong; Wu, Ping

Microbial fuel cells (MFCs) offer great promise for simultaneous treatment of wastewater and energy recovery. While past research has been based extensively on experimental studies, modelling and simulation remains scarce. A typical MFC shares many similarities with chemical fuel cells such as direct ascorbic acid fuel cells and direct methanol fuel cells. Therefore, an attempt is made to develop a MFC model similar to that for chemical fuel cells. By integrating biochemical reactions, Butler-Volmer expressions and mass/charge balances, a MFC model based on a two-chamber configuration is developed that simulates both steady and dynamic behaviour of a MFC, including voltage, power density, fuel concentration, and the influence of various parameters on power generation. Results show that the cathodic reaction is the most significant limiting factor of MFC performance. Periodic changes in the flow rate of fuel result in a boost of power output; this offers further insight into MFC behaviour. In addition to a MFC fuelled by acetate, the present method is also successfully extended to using artificial wastewater (solution of glucose and glutamic acid) as fuel. Since the proposed modelling method is easy to implement, it can serve as a framework for modelling other types of MFC and thereby will facilitate the development and scale-up of more efficient MFCs.

Design and analysis of a direct-drive wind power generator with ultra-high torque density

NASA Astrophysics Data System (ADS)

Jian, Linni; Shi, Yujun; Wei, Jin; Zheng, Yanchong

2015-05-01

In order to get rid of the nuisances caused by mechanical gearboxes, generators with low rated speed, which can be directly connected to wind turbines, are attracting increasing attention. The purpose of this paper is to propose a new direct-drive wind power generator (DWPG), which can offer ultra-high torque density. First, magnetic gear (MG) is integrated to achieve non-contact torque transmission and speed variation. Second, armature windings are engaged to achieve electromechanical energy conversion. Interior permanent magnet (PM) design on the inner rotor is adopted to boost the torque transmission capability of the integrated MG. Nevertheless, due to lack of back iron on the stator, the proposed generator does not exhibit prominent salient feature, which usually exists in traditional interior PM (IPM) machines. This makes it with good controllability and high power factor as the surface-mounted permanent magnet machines. The performance is analyzed using finite element method. Investigation on the magnetic field harmonics demonstrates that the permanent-magnetic torque offered by the MG can work together with the electromagnetic torque offered by the armature windings to balance the driving torque captured by the wind turbine. This allows the proposed generator having the potential to offer even higher torque density than its integrated MG.

Predication of different stages of Alzheimer's disease using neighborhood component analysis and ensemble decision tree.

PubMed

Jin, Mingwu; Deng, Weishu

2018-05-15

There is a spectrum of the progression from healthy control (HC) to mild cognitive impairment (MCI) without conversion to Alzheimer's disease (AD), to MCI with conversion to AD (cMCI), and to AD. This study aims to predict the different disease stages using brain structural information provided by magnetic resonance imaging (MRI) data. The neighborhood component analysis (NCA) is applied to select most powerful features for prediction. The ensemble decision tree classifier is built to predict which group the subject belongs to. The best features and model parameters are determined by cross validation of the training data. Our results show that 16 out of a total of 429 features were selected by NCA using 240 training subjects, including MMSE score and structural measures in memory-related regions. The boosting tree model with NCA features can achieve prediction accuracy of 56.25% on 160 test subjects. Principal component analysis (PCA) and sequential feature selection (SFS) are used for feature selection, while support vector machine (SVM) is used for classification. The boosting tree model with NCA features outperforms all other combinations of feature selection and classification methods. The results suggest that NCA be a better feature selection strategy than PCA and SFS for the data used in this study. Ensemble tree classifier with boosting is more powerful than SVM to predict the subject group. However, more advanced feature selection and classification methods or additional measures besides structural MRI may be needed to improve the prediction performance. Copyright © 2018 Elsevier B.V. All rights reserved.

Characterization of the Optical and X-ray Properties of the Northwestern Wisps in the Crab Nebula

NASA Technical Reports Server (NTRS)

Weisskopf, M. C.; Bucciantini, N.; Idec, W.; Nillson, K.; Schweizer, T.; Tennant, A. F.; Zanin, R.

2013-01-01

We have studied the wisps to the northwest of the Crab pulsar as part of a multi-wavelength campaign in the visible and in X-rays. Optical observations were obtained using the Nordic Optical Telescope in La Palma and X-ray observations were made with the Chandra X-ray Observatory. The observing campaign took place from October 2010 until September 2012. About once per year we observe wisps forming and peeling off from (or near) the region commonly associated with the termination shock of the pulsar wind. We find that the exact locations of the northwestern wisps in the optical and in X-rays are similar but not coincident, with X-ray wisps preferentially located closer to the pulsar. This suggests that the optical and X-ray wisps are not produced by the same particle distribution. It is also interesting to note that the optical and radio wisps are also separated from each other (Bietenholz et al. 2004). Our measurements and their implications are interpreted in terms of a Doppler-boosted ring model that has its origin in MHD modeling. While the Doppler boosting factors inferred from the X-ray wisps are consistent with current MHD simulations of PWNe, the optical boosting factors are not, and typically exceed values from MHD simulations by about a factor of 4.

A seesaw-type approach for enhancing nonlinear energy harvesting

NASA Astrophysics Data System (ADS)

Deng, Huaxia; Wang, Zhemin; Du, Yu; Zhang, Jin; Ma, Mengchao; Zhong, Xiang

2018-05-01

Harvesting sustainable mechanical energy is the ultimate objective of nonlinear energy harvesters. However, overcoming potential barriers, especially without the use of extra excitations, poses a great challenge for the development of nonlinear generators. In contrast to the existing methods, which typically modify the barrier height or utilize additional excitations, this letter proposes a seesaw-type approach to facilitate escape from potential wells by transfer of internal energy, even under low-intensity excitation. This approach is adopted in the design of a seesaw-type nonlinear piezoelectric energy harvester and the energy transfer process is analyzed by deriving expressions for the energy to reveal the working mechanism. Comparison experiments demonstrate that this approach improves energy harvesting in terms of an increase in the working frequency bandwidth by a factor of 60.14 and an increase in the maximum output voltage by a factor of 5.1. Moreover, the output power is increased by a factor of 51.3, which indicates that this approach significantly improves energy collection efficiency. This seesaw-type approach provides a welcome boost to the development of renewable energy collection methods by improving the efficiency of harvesting of low-intensity ambient mechanical energy.

Orbiter aborts from boost: Presimulation report

NASA Technical Reports Server (NTRS)

Backman, H. D.; Brechka, K. G.

1972-01-01

A description of a hybrid simulation of the 040C orbiter aborting from boost to specified landing site is provided. The simulation starts when the abort is initiated and continues until a terminal energy state (associated with the selected landing site) is reached. At abort it is assumed that all SRM's are jettisoned with the external tank remaining with the orbiter. The simulation described has six degrees of freedom with the vehicle simulated as a rigid body. A conventional form of autopilot is provided to control engine gimbaling during powered flight. An ideal form of an autopilot is provided to test conventional autopilot function and provide pseudo RCS function during coasting flight. The simulation is proposed to provide means for studies of abort guidance function and to gain information concerning ability to control the abort trajectory.

Testing and Feedback Effects on Front-End Control over Later Retrieval

ERIC Educational Resources Information Center

Thomas, Ruthann C.; McDaniel, Mark A.

2013-01-01

In 2 experiments, we explored differences in cognitive control at retrieval on a final test to better understand the mechanisms underlying the powerful boost in recall of previously tested information. Memory retrieval can be enhanced by front-end control processes that regulate the scope of retrieval or by later processes that monitor retrieval…

A State for Excellence: New Jersey Boosts Learning Power with Online Video Resources

ERIC Educational Resources Information Center

Duff, Victoria; Sauer, Wendy; Gleason, Sonia Caus

2011-01-01

The New Jersey Department of Education supports all districts with a tool kit of valuable resources for planning and creating collaborative learning structures that focus on getting results for all students. This tool kit was the basis for the creation of Learning Forward's "Becoming a Learning School" (2009). The tool kit helps…

Co-Clustering by Bipartite Spectral Graph Partitioning for Out-of-Tutor Prediction

ERIC Educational Resources Information Center

Trivedi, Shubhendu; Pardos, Zachary A.; Sarkozy, Gabor N.; Heffernan, Neil T.

2012-01-01

Learning a more distributed representation of the input feature space is a powerful method to boost the performance of a given predictor. Often this is accomplished by partitioning the data into homogeneous groups by clustering so that separate models could be trained on each cluster. Intuitively each such predictor is a better representative of…

The Power of Organizational Readiness to Boost Success with the 2008 EPAS in Social Work Education

ERIC Educational Resources Information Center

Burney Nissen, Laura

2014-01-01

Social work education is engaged in a significant evolutionary phase of its development, spearheaded by the Council on Social Work Education and the 2008 Educational Policy and Accreditation Standards (EPAS). This article suggests that an organizational change--anchored focus is a little discussed but ultimately important set of theories and…

Bottom ash boosts poor soil

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stanley, D.

1993-04-01

This article describes agricultural uses of fluidized bed bottom ash residue from burning limestone and coal in electric power generating plants: as a limestone substitute, to increase calcium levels in both soil and plants, and as a gypsom-containing soil amendment. Apples and tomatoes are the crops used. The industrial perspective and other uses of bottom ash are also briefly described.

Series Connected Converter for Control of Multi-Bus Spacecraft Power Utility

NASA Technical Reports Server (NTRS)

Beach, Raymond F. (Inventor); Brush, Andy (Inventor)

1997-01-01

The invention provides a power system using series connected regulators. Power from a source, such as a solar array, is processed through the regulators and provided to corresponding buses used to charge a battery and supply loads. The regulators employ a bypass loop around a DC-DC converter. The bypass loop connects a hot input of the converter to a return output, preferably though an inductor. Part of the current from the source passes through the bypass loop to the power bus. The converter bucks or boosts the voltage from the source to maintain the desired voltage at the bus. Thus, only part of the power is processed through the converter. The converter can also be used without the bypass loop to provide isolation. All of the converters can be substantially identical.

NTCP reduction for advanced head and neck cancer patients using proton therapy for complete or sequential boost treatment versus photon therapy.

PubMed

Jakobi, Annika; Stützer, Kristin; Bandurska-Luque, Anna; Löck, Steffen; Haase, Robert; Wack, Linda-Jacqueline; Mönnich, David; Thorwarth, Daniel; Perez, Damien; Lühr, Armin; Zips, Daniel; Krause, Mechthild; Baumann, Michael; Perrin, Rosalind; Richter, Christian

2015-01-01

To determine by treatment plan comparison differences in toxicity risk reduction for patients with head and neck squamous cell carcinoma (HNSCC) from proton therapy either used for complete treatment or sequential boost treatment only. For 45 HNSCC patients, intensity-modulated photon (IMXT) and proton (IMPT) treatment plans were created including a dose escalation via simultaneous integrated boost with a one-step adaptation strategy after 25 fractions for sequential boost treatment. Dose accumulation was performed for pure IMXT treatment, pure IMPT treatment and for a mixed modality treatment with IMXT for the elective target followed by a sequential boost with IMPT. Treatment plan evaluation was based on modern normal tissue complication probability (NTCP) models for mucositis, xerostomia, aspiration, dysphagia, larynx edema and trismus. Individual NTCP differences between IMXT and IMPT (∆NTCPIMXT-IMPT) as well as between IMXT and the mixed modality treatment (∆NTCPIMXT-Mix) were calculated. Target coverage was similar in all three scenarios. NTCP values could be reduced in all patients using IMPT treatment. However, ∆NTCPIMXT-Mix values were a factor 2-10 smaller than ∆NTCPIMXT-IMPT. Assuming a threshold of ≥ 10% NTCP reduction in xerostomia or dysphagia risk as criterion for patient assignment to IMPT, less than 15% of the patients would be selected for a proton boost, while about 50% would be assigned to pure IMPT treatment. For mucositis and trismus, ∆NTCP ≥ 10% occurred in six and four patients, respectively, with pure IMPT treatment, while no such difference was identified with the proton boost. The use of IMPT generally reduces the expected toxicity risk while maintaining good tumor coverage in the examined HNSCC patients. A mixed modality treatment using IMPT solely for a sequential boost reduces the risk by 10% only in rare cases. In contrast, pure IMPT treatment may be reasonable for about half of the examined patient cohort considering the toxicities xerostomia and dysphagia, if a feasible strategy for patient anatomy changes is implemented.

Optimization of heterologous DNA-prime, protein boost regimens and site of vaccination to enhance therapeutic immunity against human papillomavirus-associated disease.

PubMed

Peng, Shiwen; Qiu, Jin; Yang, Andrew; Yang, Benjamin; Jeang, Jessica; Wang, Joshua W; Chang, Yung-Nien; Brayton, Cory; Roden, Richard B S; Hung, Chien-Fu; Wu, T-C

2016-01-01

Human papillomavirus (HPV) has been identified as the primary etiologic factor of cervical cancer as well as subsets of anogenital and oropharyngeal cancers. The two HPV viral oncoproteins, E6 and E7, are uniquely and consistently expressed in all HPV infected cells and are therefore promising targets for therapeutic vaccination. Both recombinant naked DNA and protein-based HPV vaccines have been demonstrated to elicit HPV-specific CD8+ T cell responses that provide therapeutic effects against HPV-associated tumor models. Here we examine the immunogenicity in a preclinical model of priming with HPV DNA vaccine followed by boosting with filterable aggregates of HPV 16 L2E6E7 fusion protein (TA-CIN). We observed that priming twice with an HPV DNA vaccine followed by a single TA-CIN booster immunization generated the strongest antigen-specific CD8+ T cell response compared to other prime-boost combinations tested in C57BL/6 mice, whether naïve or bearing the HPV16 E6/E7 transformed syngeneic tumor model, TC-1. We showed that the magnitude of antigen-specific CD8+ T cell response generated by the DNA vaccine prime, TA-CIN protein vaccine boost combinatorial strategy is dependent on the dose of TA-CIN protein vaccine. In addition, we found that a single booster immunization comprising intradermal or intramuscular administration of TA-CIN after priming twice with an HPV DNA vaccine generated a comparable boost to E7-specific CD8+ T cell responses. We also demonstrated that the immune responses elicited by the DNA vaccine prime, TA-CIN protein vaccine boost strategy translate into potent prophylactic and therapeutic antitumor effects. Finally, as seen for repeat TA-CIN protein vaccination, we showed that the heterologous DNA prime and protein boost vaccination strategy is well tolerated by mice. Our results provide rationale for future clinical testing of HPV DNA vaccine prime, TA-CIN protein vaccine boost immunization regimen for the control of HPV-associated diseases.

Perspectives on the Impact of Varicella Immunization on Herpes Zoster. A Model-Based Evaluation from Three European Countries

PubMed Central

Poletti, Piero; Melegaro, Alessia; Ajelli, Marco; del Fava, Emanuele; Guzzetta, Giorgio; Faustini, Luca; Scalia Tomba, Giampaolo; Lopalco, Pierluigi; Rizzo, Caterina; Merler, Stefano; Manfredi, Piero

2013-01-01

The introduction of mass vaccination against Varicella-Zoster-Virus (VZV) is being delayed in many European countries because of, among other factors, the possibility of a large increase in Herpes Zoster (HZ) incidence in the first decades after the initiation of vaccination, due to the expected decline of the boosting of Cell Mediated Immunity caused by the reduced varicella circulation. A multi-country model of VZV transmission and reactivation, is used to evaluate the possible impact of varicella vaccination on HZ epidemiology in Italy, Finland and the UK. Despite the large uncertainty surrounding HZ and vaccine-related parameters, surprisingly robust medium-term predictions are provided, indicating that an increase in HZ incidence is likely to occur in countries where the incidence rate is lower in absence of immunization, possibly due to a higher force of boosting (e.g. Finland), whereas increases in HZ incidence might be minor where the force of boosting is milder (e.g. the UK). Moreover, a convergence of HZ post vaccination incidence levels in the examined countries is predicted despite different initial degrees of success of immunization policies. Unlike previous model-based evaluations, our investigation shows that after varicella immunization an increase of HZ incidence is not a certain fact, rather depends on the presence or absence of factors promoting a strong boosting intensity and which might or not be heavily affected by changes in varicella circulation due to mass immunization. These findings might explain the opposed empirical evidences observed about the increases of HZ in sites where mass varicella vaccination is ongoing. PMID:23613740

Rebooting Computers as Learning Machines

DOE PAGES

DeBenedictis, Erik P.

2016-06-13

Artificial neural networks could become the technological driver that replaces Moore's law, boosting computers' utlity through a process akin to automatic programming--although physics and computer architecture would are also a factor.

Rebooting Computers as Learning Machines

DOE Office of Scientific and Technical Information (OSTI.GOV)

DeBenedictis, Erik P.

Artificial neural networks could become the technological driver that replaces Moore's law, boosting computers' utlity through a process akin to automatic programming--although physics and computer architecture would are also a factor.

Herpes Zoster Risk Reduction through Exposure to Chickenpox Patients: A Systematic Multidisciplinary Review.

PubMed

Ogunjimi, Benson; Van Damme, Pierre; Beutels, Philippe

2013-01-01

Varicella-zoster virus (VZV) causes chickenpox and may subsequently reactivate to cause herpes zoster later in life. The exogenous boosting hypothesis states that re-exposure to circulating VZV can inhibit VZV reactivation and consequently also herpes zoster in VZV-immune individuals. Using this hypothesis, mathematical models predicted widespread chickenpox vaccination to increase herpes zoster incidence over more than 30 years. Some countries have postponed universal chickenpox vaccination, at least partially based on this prediction. After a systematic search and selection procedure, we analyzed different types of exogenous boosting studies. We graded 13 observational studies on herpes zoster incidence after widespread chickenpox vaccination, 4 longitudinal studies on VZV immunity after re-exposure, 9 epidemiological risk factor studies, 7 mathematical modeling studies as well as 7 other studies. We conclude that exogenous boosting exists, although not for all persons, nor in all situations. Its magnitude is yet to be determined adequately in any study field.

Polymer-Polymer Förster Resonance Energy Transfer Significantly Boosts the Power Conversion Efficiency of Bulk-Heterojunction Solar Cells.

PubMed

Gupta, Vinay; Bharti, Vishal; Kumar, Mahesh; Chand, Suresh; Heeger, Alan J

2015-08-01

Optically resonant donor polymers can exploit a wider range of the solar spectrum effectively without a complicated tandem design in an organic solar cell. Ultrafast Förster resonance energy transfer (FRET) in a polymer-polymer system that significantly improves the power conversion efficiency in bulk heterojunction polymer solar cells from 6.8% to 8.9% is demonstrated, thus paving the way to achieving 15% efficient solar cells. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Gradient boosting machine for modeling the energy consumption of commercial buildings

DOE PAGES

Touzani, Samir; Granderson, Jessica; Fernandes, Samuel

2017-11-26

Accurate savings estimations are important to promote energy efficiency projects and demonstrate their cost-effectiveness. The increasing presence of advanced metering infrastructure (AMI) in commercial buildings has resulted in a rising availability of high frequency interval data. These data can be used for a variety of energy efficiency applications such as demand response, fault detection and diagnosis, and heating, ventilation, and air conditioning (HVAC) optimization. This large amount of data has also opened the door to the use of advanced statistical learning models, which hold promise for providing accurate building baseline energy consumption predictions, and thus accurate saving estimations. The gradientmore » boosting machine is a powerful machine learning algorithm that is gaining considerable traction in a wide range of data driven applications, such as ecology, computer vision, and biology. In the present work an energy consumption baseline modeling method based on a gradient boosting machine was proposed. To assess the performance of this method, a recently published testing procedure was used on a large dataset of 410 commercial buildings. The model training periods were varied and several prediction accuracy metrics were used to evaluate the model's performance. The results show that using the gradient boosting machine model improved the R-squared prediction accuracy and the CV(RMSE) in more than 80 percent of the cases, when compared to an industry best practice model that is based on piecewise linear regression, and to a random forest algorithm.« less

Gradient boosting machine for modeling the energy consumption of commercial buildings

DOE Office of Scientific and Technical Information (OSTI.GOV)

Touzani, Samir; Granderson, Jessica; Fernandes, Samuel

Accurate savings estimations are important to promote energy efficiency projects and demonstrate their cost-effectiveness. The increasing presence of advanced metering infrastructure (AMI) in commercial buildings has resulted in a rising availability of high frequency interval data. These data can be used for a variety of energy efficiency applications such as demand response, fault detection and diagnosis, and heating, ventilation, and air conditioning (HVAC) optimization. This large amount of data has also opened the door to the use of advanced statistical learning models, which hold promise for providing accurate building baseline energy consumption predictions, and thus accurate saving estimations. The gradientmore » boosting machine is a powerful machine learning algorithm that is gaining considerable traction in a wide range of data driven applications, such as ecology, computer vision, and biology. In the present work an energy consumption baseline modeling method based on a gradient boosting machine was proposed. To assess the performance of this method, a recently published testing procedure was used on a large dataset of 410 commercial buildings. The model training periods were varied and several prediction accuracy metrics were used to evaluate the model's performance. The results show that using the gradient boosting machine model improved the R-squared prediction accuracy and the CV(RMSE) in more than 80 percent of the cases, when compared to an industry best practice model that is based on piecewise linear regression, and to a random forest algorithm.« less

On the importance of minimizing "coast-time" in x-ray driven inertially confined fusion implosions

NASA Astrophysics Data System (ADS)

Hurricane, O. A.; Kritcher, A.; Callahan, D. A.; Landen, O.; Patel, P. K.; Springer, P. T.; Casey, D. T.; Dewald, E. L.; Dittrich, T. R.; Döppner, T.; Hinkel, D. E.; Berzak Hopkins, L. F.; Kline, J.; Le Pape, S.; Ma, T.; MacPhee, A. G.; Moore, A.; Pak, A.; Park, H.-S.; Ralph, J.; Salmonson, J. D.; Widmann, K.

2017-09-01

By the time an inertially confined fusion (ICF) implosion has converged a factor of 20, its surface area has shrunk 400 × , making it an inefficient x-ray energy absorber. So, ICF implosions are traditionally designed to have the laser drive shut off at a time, toff, well before bang-time, tBT, for a coast-time of t coast = t B T - t o f f > 1 ns. High-foot implosions on NIF showed a strong dependence of many key ICF performance quantities on reduced coast-time (by extending the duration of laser power after the peak power is first reached), most notably stagnation pressure and fusion yield. Herein we show that the ablation pressure, pabl, which drives high-foot implosions, is essentially triangular in temporal shape, and that reducing tcoast boosts pabl by as much as ˜ 2 × prior to stagnation thus increasing fuel and hot-spot compression and implosion speed. One-dimensional simulations are used to track hydrodynamic characteristics for implosions with various coast-times and various assumed rates of hohlraum cooling after toff to illustrate how the late-time conditions exterior to the implosion can impact the fusion performance. A simple rocket model-like analytic theory demonstrates that reducing coast-time can lead to a ˜ 15 % higher implosion velocity because the reduction in x-ray absorption efficiency at late-time is somewhat compensated by small ( ˜ 5 % - 10 %) ablator mass remaining. Together with the increased ablation pressure, the additional implosion speed for short coast-time implosions can boost the stagnation pressure by ˜ 2 × as compared to a longer coast-time version of the same implosion. Four key dimensionless parameters are identified and we find that reducing coast-time to as little as 500 ps still provides some benefit. Finally, we show how the high-foot implosion data is consistent with the above mentioned picture.

On the importance of minimizing “coast-time” in x-ray driven inertially confined fusion implosions

DOE PAGES

Hurricane, O. A.; Kritcher, A.; Callahan, D. A.; ...

2017-09-01

By the time an inertially confined fusion (ICF) implosion has converged a factor of 20, its surface area has shrunk 400×, making it an inefficient x-ray energy absorber. So, ICF implosions are traditionally designed to have the laser drive shut off at a time, t off, well before bang-time, t BT, for a coast-time of t coast = t BT – t off > 1 ns. High-foot implosions on NIF showed a strong dependence of many key ICF performance quantities on reduced coast-time (by extending the duration of laser power after the peak power is first reached), most notably stagnationmore » pressure and fusion yield. Herein we show that the ablation pressure, p abl, which drives high-foot implosions, is essentially triangular in temporal shape, and that reducing t coast boosts p abl by as much as ~2× prior to stagnation thus increasing fuel and hot-spot compression and implosion speed. One-dimensional simulations are used to track hydrodynamic characteristics for implosions with various coast-times and various assumed rates of hohlraum cooling after t off to illustrate how the late-time conditions exterior to the implosion can impact the fusion performance. A simple rocket model-like analytic theory demonstrates that reducing coast-time can lead to a ~15% higher implosion velocity because the reduction in x-ray absorption efficiency at late-time is somewhat compensated by small (~5%–10%) ablator mass remaining. Together with the increased ablation pressure, the additional implosion speed for short coast-time implosions can boost the stagnation pressure by ~2× as compared to a longer coast-time version of the same implosion. Four key dimensionless parameters are identified and we find that reducing coast-time to as little as 500 ps still provides some benefit. Lastly, we show how the high-foot implosion data is consistent with the above mentioned picture.« less

On the importance of minimizing “coast-time” in x-ray driven inertially confined fusion implosions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hurricane, O. A.; Kritcher, A.; Callahan, D. A.

By the time an inertially confined fusion (ICF) implosion has converged a factor of 20, its surface area has shrunk 400×, making it an inefficient x-ray energy absorber. So, ICF implosions are traditionally designed to have the laser drive shut off at a time, t off, well before bang-time, t BT, for a coast-time of t coast = t BT – t off > 1 ns. High-foot implosions on NIF showed a strong dependence of many key ICF performance quantities on reduced coast-time (by extending the duration of laser power after the peak power is first reached), most notably stagnationmore » pressure and fusion yield. Herein we show that the ablation pressure, p abl, which drives high-foot implosions, is essentially triangular in temporal shape, and that reducing t coast boosts p abl by as much as ~2× prior to stagnation thus increasing fuel and hot-spot compression and implosion speed. One-dimensional simulations are used to track hydrodynamic characteristics for implosions with various coast-times and various assumed rates of hohlraum cooling after t off to illustrate how the late-time conditions exterior to the implosion can impact the fusion performance. A simple rocket model-like analytic theory demonstrates that reducing coast-time can lead to a ~15% higher implosion velocity because the reduction in x-ray absorption efficiency at late-time is somewhat compensated by small (~5%–10%) ablator mass remaining. Together with the increased ablation pressure, the additional implosion speed for short coast-time implosions can boost the stagnation pressure by ~2× as compared to a longer coast-time version of the same implosion. Four key dimensionless parameters are identified and we find that reducing coast-time to as little as 500 ps still provides some benefit. Lastly, we show how the high-foot implosion data is consistent with the above mentioned picture.« less

A BATSE investigation of radiation belt electrons precipitated by VLF waves

NASA Technical Reports Server (NTRS)

Datlowe, Dayton W.

1995-01-01

The Compton Observatory commonly encounters fluxes of energetic electrons which have been scattered from the inner radiation belt to the path of the satellite by resonant interactions with VLF waves from powerful man-made transmitters. The present investigation was motivated by the fact that in the Fall of 1993, the Gamma Ray Observatory was boosted from a 650 km altitude circular orbit to a 750 km altitude circular orbit. This was an opportunity, for the first time, to make observations at two different altitudes using the same instrument. We have examined DISCLA data from the Burst & Transient Source Experiment (BATSE) experiment from 1 Sep. 1993 to 29 Jan. 1994. During the period of study we identified 48 instances of the satellite encountering a cloud of energetic electrons which had been scattered by VLF transmitters. We find that boosting the altitude of the circular orbit from 650 km to 750 km increased the intensity of cyclotron resonance scattered electrons by a factor of two. To search for long term changes in the cyclotron resonance precipitation, we have compared the approx. 750 km altitude data from 106 days at the end of 1993 with data at the same altitudes and time of year in 1991. The cyclotron resonance events in 1991 were three times more frequent and 25% of those cases were more intense than any seen in the 1993 data. We attribute this difference to increased level of geomagnetic activity in 1991 near the Solar Maximum.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ruther, Rose E.; Sun, Che -Nan; Holliday, Adam

A simple electrolyte consisting of NaPF 6 salt in 1,2-dimethoxyethane (DME) can extend the voltage window of electric double-layer capacitors (EDLCs) to >3.5 V. DME does not passivate carbon electrodes at very negative potentials (near Na/Na +), extending the practical voltage window by about 1.0 V compared to standard, non-aqueous electrolytes based on acetonitrile. The voltage window is demonstrated in two- and three-electrode cells using a combination of electrochemical impedance spectroscopy (EIS), charge-discharge cycling, and measurements of leakage current. DME-based electrolytes cannot match the high conductivity of acetonitrile solutions, but they can satisfy applications that demand high energy density atmore » moderate power. The conductivity of NaPF 6 in DME is comparable to commercial lithium-ion battery electrolytes and superior to most ionic liquids. Lastly, factors that limit the voltage window and EDLC energy density are discussed, and strategies to further boost energy density are proposed.« less

Natural products in medicine: transformational outcome of synthetic chemistry.

PubMed

Szychowski, Janek; Truchon, Jean-François; Bennani, Youssef L

2014-11-26

This review brings to the forefront key synthetic modifications on natural products (NPs) that have yielded successful drugs. The emphasis is placed on the power of targeted chemical transformations in enhancing the therapeutic value of NPs through optimization of pharmacokinetics, stability, potency, and/or selectivity. Multiple classes of NPs such as macrolides, opioids, steroids, and β-lactams used to treat a variety of conditions such as cancers, infections, inflammation are exemplified. Molecular modeling or X-ray structures of NP/protein complexes supporting the observed boost in therapeutic value of the modified NPs are also discussed. Significant advancement in synthetic chemistry, in structure determination, and in the understanding of factors controlling pharmacokinetics can now better position drug discovery teams to undertake NPs as valuable leads. We hope that the beneficial NPs synthetic modifications outlined here will reignite medicinal chemists' interest in NPs and their derivatives.

LED-pumped Alexandrite laser oscillator and amplifier

NASA Astrophysics Data System (ADS)

Pichon, Pierre; Blanchot, Jean-Philippe; Balembois, François; Druon, Frédéric; Georges, Patrick

2018-02-01

In this paper, we report the first LED-pumped transition-metal-doped laser oscillator and amplifier based on an alexandrite crystal (Cr3+:BeAl2O4). A Ce:YAG luminescent concentrator illuminated by blue LEDs is used to reach higher pump powers than with LEDs alone. The luminescent 200-mm-long-composit luminescent concentrator involving 2240 LEDs can delivers up to 268 mJ for a peak irradiance of 8.5 kW/cm2. In oscillator configuration, an LED-pumped alexandrite laser delivering an energy of 2.9 mJ at 748 nm in free running operation is demonstrated. In the cavity, we measured a double pass small signal gain of 1.28, in good agreement with numerical simulations. As amplifier, the system demonstrated to boost a CW Ti:sapphire laser by a factor of 4 at 750 nm in 8 passes with a large tuning range from 710 nm to 800 nm.

Plasmon mass scale in two-dimensional classical nonequilibrium gauge theory

NASA Astrophysics Data System (ADS)

Lappi, T.; Peuron, J.

2018-02-01

We study the plasmon mass scale in classical gluodynamics in a two-dimensional configuration that mimics the boost-invariant initial color fields in a heavy-ion collision. We numerically measure the plasmon mass scale using three different methods: a hard thermal loop (HTL) expression involving the quasiparticle spectrum constructed from Coulomb gauge field correlators, an effective dispersion relation, and the measurement of oscillations between electric and magnetic energies after introducing a spatially uniform perturbation to the electric field. We find that the HTL expression and the uniform electric field measurement are in rough agreement. The effective dispersion relation agrees with other methods within a factor of 2. We also study the dependence on time and occupation number, observing similar trends as in three spatial dimensions, where a power-law dependence sets in after an occupation-number-dependent transient time. We observe a decrease of the plasmon mass squared as t-1 / 3 at late times.

Light-induced lattice expansion leads to high-efficiency perovskite solar cells

NASA Astrophysics Data System (ADS)

Tsai, Hsinhan; Asadpour, Reza; Blancon, Jean-Christophe; Stoumpos, Constantinos C.; Durand, Olivier; Strzalka, Joseph W.; Chen, Bo; Verduzco, Rafael; Ajayan, Pulickel M.; Tretiak, Sergei; Even, Jacky; Alam, Muhammad Ashraf; Kanatzidis, Mercouri G.; Nie, Wanyi; Mohite, Aditya D.

2018-04-01

Light-induced structural dynamics plays a vital role in the physical properties, device performance, and stability of hybrid perovskite–based optoelectronic devices. We report that continuous light illumination leads to a uniform lattice expansion in hybrid perovskite thin films, which is critical for obtaining high-efficiency photovoltaic devices. Correlated, in situ structural and device characterizations reveal that light-induced lattice expansion benefits the performances of a mixed-cation pure-halide planar device, boosting the power conversion efficiency from 18.5 to 20.5%. The lattice expansion leads to the relaxation of local lattice strain, which lowers the energetic barriers at the perovskite-contact interfaces, thus improving the open circuit voltage and fill factor. The light-induced lattice expansion did not compromise the stability of these high-efficiency photovoltaic devices under continuous operation at full-spectrum 1-sun (100 milliwatts per square centimeter) illumination for more than 1500 hours.

Panchromatic polymer-polymer ternary solar cells enhanced by Forster resonance energy transfer and solvent vapor annealing

DOE PAGES

Goh, Tenghooi; Sfeir, Matthew Y.; Huang, Jing -Shun; ...

2015-08-04

Thanks to the bulk-heterojunction (BHJ) feature of polymer solar cells (PSC), additional light active components can be added with ease to form ternary solar cells. This strategy has achieved great success largely due to expanded spectral response range and improved power conversion efficiency (PCE) without incurring excessive processing costs. Here, we report ternary blend polymer–polymer solar cells comprised of PTB7, P3HT, and PC71BM with PCE as high as 8.2%. Analyses of femtosecond time resolved photoluminescence and transient absorption spectroscopy data confirm that P3HT is effective in transferring energy non-radiatively by inducing excitons and prolonging their overall lifetime in PTB7. Asmore » a result, solvent vapor annealing (SVA) treatment was employed to rectify the overly-coarse morphology, thus enhancing the fill factor, reducing interfacial recombination, and boosting the PCE to 8.7%.« less

Enhancement of laser power-efficiency by control of spatial hole burning interactions

NASA Astrophysics Data System (ADS)

Ge, Li; Malik, Omer; Türeci, Hakan E.

2014-11-01

The laser is an out-of-equilibrium nonlinear wave system where the interplay of the cavity geometry and nonlinear wave interactions mediated by the gain medium determines the self-organized oscillation frequencies and the associated spatial field patterns. In the steady state, a constant energy flux flows through the laser from the pump to the far field, with the ratio of the total output power to the input power determining the power-efficiency. Although nonlinear wave interactions have been modelled and well understood since the early days of laser theory, their impact on the power-efficiency of a laser system is poorly understood. Here, we show that spatial hole burning interactions generally decrease the power-efficiency. We then demonstrate how spatial hole burning interactions can be controlled by a spatially tailored pump profile, thereby boosting the power-efficiency, in some cases by orders of magnitude.

A real time status monitor for transistor bank driver power limit resistor in boost injection kicker power supply

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mi, J.; Tan, Y.; Zhang, W.

2011-03-28

For years suffering of Booster Injection Kicker transistor bank driver regulator troubleshooting, a new real time monitor system has been developed. A simple and floating circuit has been designed and tested. This circuit monitor system can monitor the driver regulator power limit resistor status in real time and warn machine operator if the power limit resistor changes values. This paper will mainly introduce the power supply and the new designed monitoring system. This real time resistor monitor circuit shows a useful method to monitor some critical parts in the booster pulse power supply. After two years accelerator operation, it showsmore » that this monitor works well. Previously, we spent a lot of time in booster machine trouble shooting. We will reinstall all 4 PCB into Euro Card Standard Chassis when the power supply system will be updated.« less

Boost Irradiation Integrated to Whole Brain Radiotherapy in the Management of Brain Metastases.

PubMed

Dobi, Ágnes; Fodor, Emese; Maráz, Anikó; Együd, Zsófia; Cserháti, Adrienne; Tiszlavicz, László; Reisz, Zita; Barzó, Pál; Varga, Zoltán; Hideghéty, Katalin

2018-01-17

Our retrospective analysis aimed to evaluate the clinical value of dose intensification schemes: WBRT and consecutive, delayed, or simultaneous integrated boost (SIB) in brain metastasis (BM) management. Clinical data and overall survival (OS) of 468 patients with BM from various primaries treated with 10 × 3 Gy WBRT (n = 195), WBRT+ 10 × 2 Gy boost (n = 125), or simultaneously 15 × 2.2 Gy WBRT+0.7 Gy boost (n = 148) during a 6-year period were statistically analysed. Significant difference in OS could be detected with additional boost to WBRT (3.3 versus 6.5 months) and this difference was confirmed for BMs of lung cancer and melanoma and both for oligo- and multiplex lesions. The OS was prolonged for the RPA 2 and RPA3 categories, if patients received escalated dose, 4.0 vs. 7.7 months; (p = 0.002) in class RPA2 and 2.6 vs. 4.2 months; (p < 0.0001) in the class RPA 3 respectively. The significant difference in OS was also achieved with SIB. The shortened overall treatment time of SIB with lower WBRT fraction dose exhibited survival benefit over WBRT alone, and could be applied for patients developing BM even with unfavourable prognostic factors. These results warrant for further study of this approach with dose escalation using the lately available solutions for hippocampus sparing and fractionated stereotactic irradiation. The simultaneous delivery of WBRT with reduced fraction dose and boost proved to be advantageous prolonging the OS with shortened treatment time and reduced probability for cognitive decline development even for patients with poor performance status and progressing extracranial disease.

Effects of in-competitive season power-oriented and heavy resistance lower-body training on performance of elite female water polo players.

PubMed

Veliz, Rafael R; Suarez-Arrones, Luis; Requena, Bernardo; Haff, G Gregory; Feito, Javier; Sáez de Villarreal, Eduardo

2015-02-01

We examined the effect of 16 weeks of lower-body resistance and power-oriented training on key performance measures of elite female water polo players. Twenty-one players were randomly assigned to 2 groups: control group (C) who did in-water training only and a lower body strength (LBS) group, who performed resistance (full squat and split squat) and jump and power-oriented lower-body training (countermovement jump [CMJ] loaded and CMJ) sessions (twice per week) in addition to the same in-water training. In-water training was conducted 5 days per week for a total of 16 weeks. Twenty-meter maximal sprint swim (MSS), lower-body strength during 1 repetition maximum (1RM) full squat (FS), in-water boost and CMJ, and Throwing speed (ThS) were measured before and after the training. Pretraining results showed no statistically significant differences between the groups in any of the variables tested. After 16 weeks, no statistically significant improvement was found in any of the variables measured in the C group, however, significant improvement was found in the LBS group: in-water boost (4.6 cm, 12.02%, effect size [ES] = 1.02), CMJ (2.4 cm, 8.66%, ES = 0.85), FS (12.7 kg, 20.99%, ES = 2.41), and ThS (3.4 km·h, 6.86%, ES = 3.44). Lower-body resistance and power-oriented training in female water polo players for 16 weeks produced significant improvements in performance qualities highly specific to water polo performance. Therefore, we propose modifications to current training methodology for female water polo players to include resistance and power-oriented training during the competitive season in this sport.

Estimation of energetic efficiency of heat supply in front of the aircraft at supersonic accelerated flight. Part 1. Mathematical models

NASA Astrophysics Data System (ADS)

Latypov, A. F.

2008-12-01

Fuel economy at boost trajectory of the aerospace plane was estimated during energy supply to the free stream. Initial and final flight velocities were specified. The model of a gliding flight above cold air in an infinite isobaric thermal wake was used. The fuel consumption rates were compared at optimal trajectory. The calculations were carried out using a combined power plant consisting of ramjet and liquid-propellant engine. An exergy model was built in the first part of the paper to estimate the ramjet thrust and specific impulse. A quadratic dependence on aerodynamic lift was used to estimate the aerodynamic drag of aircraft. The energy for flow heating was obtained at the expense of an equivalent reduction of the exergy of combustion products. The dependencies were obtained for increasing the range coefficient of cruise flight for different Mach numbers. The second part of the paper presents a mathematical model for the boost interval of the aircraft flight trajectory and the computational results for the reduction of fuel consumption at the boost trajectory for a given value of the energy supplied in front of the aircraft.

Germline replacement by blastula cell transplantation in the fish medaka.

PubMed

Li, Mingyou; Hong, Ni; Xu, Hongyan; Song, Jianxing; Hong, Yunhan

2016-07-13

Primordial germ cell (PGC) specification early in development establishes the germline for reproduction and reproductive technologies. Germline replacement (GR) is a powerful tool for conservation of valuable or endangered animals. GR is achievable by germ cell transplantation into the PGC migration pathway or gonads. Blastula cell transplantation (BCT) can also lead to the chimeric germline containing PGCs of both donor and host origins. It has remained largely unknown whether BCT is able to achieve GR at a high efficiency. Here we report efficient GR by BCT into blastula embryos in the fish medaka (Oryzias latipes). Specifically, dnd depletion completely ablated host PGCs and fertility, and dnd overexpression remarkably boosted PGCs in donor blastulae. BCT between normal donor and host produced a germline transmission rate of ~4%. This rate was enhanced up to ~30% upon PGC boosting in donors. Most importantly, BCT between PGC-boosted donors and PGC-ablated hosts led to more than 90% fertility restoration and 100% GR. Therefore, BCT features an extremely high efficiency of fertility recovery and GR in medaka. This finding makes medaka an ideal model to analyze genetic and physiological donor-host compatibilities for BCT-mediated surrogate production and propagation of endangered lower vertebrates and biodiversity.

Germline replacement by blastula cell transplantation in the fish medaka

PubMed Central

Li, Mingyou; Hong, Ni; Xu, Hongyan; Song, Jianxing; Hong, Yunhan

2016-01-01

Primordial germ cell (PGC) specification early in development establishes the germline for reproduction and reproductive technologies. Germline replacement (GR) is a powerful tool for conservation of valuable or endangered animals. GR is achievable by germ cell transplantation into the PGC migration pathway or gonads. Blastula cell transplantation (BCT) can also lead to the chimeric germline containing PGCs of both donor and host origins. It has remained largely unknown whether BCT is able to achieve GR at a high efficiency. Here we report efficient GR by BCT into blastula embryos in the fish medaka (Oryzias latipes). Specifically, dnd depletion completely ablated host PGCs and fertility, and dnd overexpression remarkably boosted PGCs in donor blastulae. BCT between normal donor and host produced a germline transmission rate of ~4%. This rate was enhanced up to ~30% upon PGC boosting in donors. Most importantly, BCT between PGC-boosted donors and PGC-ablated hosts led to more than 90% fertility restoration and 100% GR. Therefore, BCT features an extremely high efficiency of fertility recovery and GR in medaka. This finding makes medaka an ideal model to analyze genetic and physiological donor-host compatibilities for BCT-mediated surrogate production and propagation of endangered lower vertebrates and biodiversity. PMID:27406328

Cholelithiasis and Nephrolithiasis in HIV-Positive Patients in the Era of Combination Antiretroviral Therapy

PubMed Central

Lin, Kuan-Yin; Liao, Sih-Han; Liu, Wen-Chun; Cheng, Aristine; Lin, Shu-Wen; Chang, Sui-Yuan; Tsai, Mao-Song; Kuo, Ching-Hua; Wu, Mon-Ro; Wang, Hsiu-Po; Hung, Chien-Ching; Chang, Shan-Chwen

2015-01-01

Objectives This study aimed to describe the epidemiology and risk factors of cholelithiasis and nephrolithiasis among HIV-positive patients in the era of combination antiretroviral therapy. Methods We retrospectively reviewed the medical records of HIV-positive patients who underwent routine abdominal sonography for chronic viral hepatitis, fatty liver, or elevated aminotransferases between January 2004 and January 2015. Therapeutic drug monitoring of plasma concentrations of atazanavir was performed and genetic polymorphisms, including UDP-glucuronosyltransferase (UGT) 1A1*28 and multidrug resistance gene 1 (MDR1) G2677T/A, were determined in a subgroup of patients who received ritonavir-boosted or unboosted atazanavir-containing combination antiretroviral therapy. Information on demographics, clinical characteristics, and laboratory testing were collected and analyzed. Results During the 11-year study period, 910 patients who underwent routine abdominal sonography were included for analysis. The patients were mostly male (96.9%) with a mean age of 42.2 years and mean body-mass index of 22.9 kg/m2 and 85.8% being on antiretroviral therapy. The anchor antiretroviral agents included non-nucleoside reverse-transcriptase inhibitors (49.3%), unboosted atazanavir (34.4%), ritonavir-boosted lopinavir (20.4%), and ritonavir-boosted atazanavir (5.5%). The overall prevalence of cholelithiasis and nephrolithiasis was 12.5% and 8.2%, respectively. Among 680 antiretroviral-experienced patients with both baseline and follow-up sonography, the crude incidence of cholelithiasis and nephrolithiasis was 4.3% and 3.7%, respectively. In multivariate analysis, the independent factors associated with incident cholelithiasis were exposure to ritonavir-boosted atazanavir for >2 years (adjusted odds ratio [AOR], 6.29; 95% confidence interval [CI], 1.12–35.16) and older age (AOR, 1.04; 95% CI, 1.00–1.09). The positive association between duration of exposure to ritonavir-boosted atazanavir and incident cholelithiasis was also found (AOR, per 1-year exposure, 1.49; 95% CI, 1.05–2.10). The associated factors with incident nephrolithiasis were hyperlipidemia (AOR, 3.97; 95% CI, 1.32–11.93), hepatitis B or C coinfection (AOR, 3.41; 95% CI, 1.09–10.62), and exposure to abacavir (AOR, 12.01; 95% CI, 1.54–93.54). Of 180 patients who underwent therapeutic drug monitoring of plasma atazanavir concentrations and pharmacogenetic investigations, we found that the atazanavir concentrations and UGT 1A1*28 and MDR1 G2677T/A polymorphisms were not statistically significantly associated with incident cholelithiasis and nephrolithiasis. Conclusions In HIV-positive patients in the era of combination antiretroviral therapy, a high prevalence of cholelithiasis and nephrolithiasis was observed, and exposure to ritonavir-boosted atazanavir for >2 years was associated with incident cholelithiasis. PMID:26360703

A prediction model of short-term ionospheric foF2 Based on AdaBoost

NASA Astrophysics Data System (ADS)

Zhao, Xiukuan; Liu, Libo; Ning, Baiqi

Accurate specifications of spatial and temporal variations of the ionosphere during geomagnetic quiet and disturbed conditions are critical for applications, such as HF communications, satellite positioning and navigation, power grids, pipelines, etc. Therefore, developing empirical models to forecast the ionospheric perturbations is of high priority in real applications. The critical frequency of the F2 layer, foF2, is an important ionospheric parameter, especially for radio wave propagation applications. In this paper, the AdaBoost-BP algorithm is used to construct a new model to predict the critical frequency of the ionospheric F2-layer one hour ahead. Different indices were used to characterize ionospheric diurnal and seasonal variations and their dependence on solar and geomagnetic activity. These indices, together with the current observed foF2 value, were input into the prediction model and the foF2 value at one hour ahead was output. We analyzed twenty-two years’ foF2 data from nine ionosonde stations in the East-Asian sector in this work. The first eleven years’ data were used as a training dataset and the second eleven years’ data were used as a testing dataset. The results show that the performance of AdaBoost-BP is better than those of BP Neural Network (BPNN), Support Vector Regression (SVR) and the IRI model. For example, the AdaBoost-BP prediction absolute error of foF2 at Irkutsk station (a middle latitude station) is 0.32 MHz, which is better than 0.34 MHz from BPNN, 0.35 MHz from SVR and also significantly outperforms the IRI model whose absolute error is 0.64 MHz. Meanwhile, AdaBoost-BP prediction absolute error at Taipei station from the low latitude is 0.78 MHz, which is better than 0.81 MHz from BPNN, 0.81 MHz from SVR and 1.37 MHz from the IRI model. Finally, the variety characteristics of the AdaBoost-BP prediction error along with seasonal variation, solar activity and latitude variation were also discussed in the paper.

MicroSensors Systems: detection of a dismounted threat

NASA Astrophysics Data System (ADS)

Davis, Bill; Berglund, Victor; Falkofske, Dwight; Krantz, Brian

2005-05-01

The Micro Sensor System (MSS) is a layered sensor network with the goal of detecting dismounted threats approaching high value assets. A low power unattended ground sensor network is dependant on a network protocol for efficiency in order to minimize data transmissions after network establishment. The reduction of network 'chattiness' is a primary driver for minimizing power consumption and is a factor in establishing a low probability of detection and interception. The MSS has developed a unique protocol to meet these challenges. Unattended ground sensor systems are most likely dependant on batteries for power which due to size determines the ability of the sensor to be concealed after placement. To minimize power requirements, overcome size limitations, and maintain a low system cost the MSS utilizes advanced manufacturing processes know as Fluidic Self-Assembly and Chip Scale Packaging. The type of sensing element and the ability to sense various phenomenologies (particularly magnetic) at ranges greater than a few meters limits the effectiveness of a system. The MicroSensor System will overcome these limitations by deploying large numbers of low cost sensors, which is made possible by the advanced manufacturing process used in production of the sensors. The MSS program will provide unprecedented levels of real-time battlefield information which greatly enhances combat situational awareness when integrated with the existing Command, Control, Communications, Computers, Intelligence, Surveillance and Reconnaissance (C4ISR) infrastructure. This system will provide an important boost to realizing the information dominant, network-centric objective of Joint Vision 2020.

1998 News Releases | NREL

Science.gov Websites

Community - (5/4/98) High School Students Compete in Solar-Powered Bike Race - (4/23/98) New Battery Testing Facility Could Boost Future of Electric Vehicles - (4/21/98) NREL Publications Win Awards - (4/17/98) Local Students Celebrate Earth Day at NREL - (4/17/98) One-Step Device Converts Water, Sunlight Into Fuel of the

Addressing the STEM Challenge by Expanding Specialty Math and Science High Schools

ERIC Educational Resources Information Center

Atkinson, Robert D.; Hugo, Janet; Lundgren, Dennis; Shapiro, Martin J.; Thomas, Jerald

2007-01-01

If America is to succeed in the innovation-powered global economy, boosting math and science skills will be critical. This is why a wide array of task forces and organizations has recently raised the clarion call for more and better scientists and engineers. While the policy proposals offered are wide ranging, one key policy innovation has…

Regulation of a lightweight high efficiency capacitator diode voltage multiplier dc-dc converter

NASA Technical Reports Server (NTRS)

Harrigill, W. T., Jr.; Myers, I. T.

1976-01-01

A method for the regulation of a capacitor diode voltage multiplier dc-dc converter has been developed which has only minor penalties in weight and efficiency. An auxiliary inductor is used, which only handles a fraction of the total power, to control the output voltage through a pulse width modulation method in a buck boost circuit.

Recession on Top of Energy Crisis May Mean Power Boost for Universities

ERIC Educational Resources Information Center

Basken, Paul

2009-01-01

For many Americans, the confluence of a recession and a growing realization that the nation needs to end its reliance on fossil fuels seems like a double dose of bad news. But for the nation's research universities, it may be an opportunity. A Brookings Institution, a policy-study group with ties to the Democratic leaders now controlling the White…

A Surveillance and Targeting System for an Unmanned Ground Vehicle

DTIC Science & Technology

1990-08-01

CHARACTERISTICS - SELECTABLE INFRASONIC AND ULTRASONIC FREQUENCY SHIFTING CAPABILITY - SUPER-BINAURAL CONFIGURATION ANGLE AND PICKUP SEPARATION GREATER THAN...HUMAN HEAD - VARIABLE GAIN WITH CLIPPING - INTEGRATABLE INTO TOV OPERATOR HELMET - CONTROL INTERFACE: VOLUME UP/DOWN, SONIC ON/OFF, ULTRA ON/OFF... INFRA ON/OFF, BOOST HI/MED/OFF ----- UGV/TOV ----- ---- AUVS/DAYTON ---- LASER SAFETY IMPLICATIONS IMPLICATIONS FOR DESIGN: - POWER UP SEQUENCE - ABORT

"Abolish the White Race" or "Transfer Economic Power to the People"?: Some Educational Implications

ERIC Educational Resources Information Center

Cole, Mike

2012-01-01

"Race Traitor", a movement founded by Noel Ignatiev and John Garvey, has been given a boost in recent months in three different arenas: the Occupy movement; an antiracist advertising campaign; and in an academic journal. With respect to the last, which is the main focus of this paper, Critical Race Theorists John Preston and Charlotte…

The Impact of Education on the Economy among the Baiga Tribe in Madhya Pradesh, India: A Brief Note

ERIC Educational Resources Information Center

Jain, A. K.; Sharma, A. N.

2009-01-01

Literacy is a powerful instrument to boost the economy in the form of providing positive attitudes and perceptions that can contribute to an improved daily life. Further, it plays an important role in determining the ecological condition, use and uptake of health-care facilities, awareness of different aspects of socio-religious and taboo…

Movement in the Classroom: Boosting Brain Power, Fighting Obesity

ERIC Educational Resources Information Center

Reilly, Erin; Buskist, Connie; Gross, Michael K.

2012-01-01

Childhood obesity in the United States is on the rise and cannot continue to be ignored. Already one-third of children in the United States are overweight (Centers for Disease Control and Prevention [CDC] 2010a), and it did not take long to get there. Since 1980, the number of overweight children doubled and the number of overweight adolescents…

@NWTC Newsletter: Summer 2014 | Wind | NREL

Science.gov Websites

, Developmental Role in Major Wind Journal Boosting Wind Plant Power Output by 4%-5% through Coordinated Turbine . Part 2: Wind Farm Wake Models New Framework Transforms FAST Wind Turbine Modeling Tool (Fact Sheet ) Sensitivity Analysis of Wind Plant Performance to Key Turbine Design Parameters: A Systems Engineering

76 FR 60710 - Airworthiness Directives; The Boeing Company Model 737-600, -700, -700C, -800, and -900 Series...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-30

... Bulletin 737-28A1201, Revision 1, dated May 28, 2009. Subject (d) Joint Aircraft System Component (JASC... control relays in the P91 and P92 power distribution panels for the fuel boost and override pumps with new... INFORMATION CONTACT: Georgios Roussos, Aerospace Engineer, Systems and Equipment Branch, ANM-130S, FAA...

Alternative Fuels Data Center: Propane Powers School Buses in Tuscaloosa,

Science.gov Websites

Efficiency March 8, 2014 Renzenberger Inc Saves Money With Propane Vans Feb. 1, 2014 Photo of a school bus and Plug-In Electric Vehicles March 31, 2012 Natural Gas School Buses Help Kansas City Save Money Nov Electric Shuttle Buses Offer Free Rides in Maryland June 18, 2010 Electric Trolley Boosts Business in

Orbit transfer vehicle advanced expander cycle engine point design study. Volume 2: Study results

NASA Technical Reports Server (NTRS)

Diem, H. G.

1980-01-01

The design characteristics of the baseline engine configuration of the advanced expander cycle engine are described. Several aspects of engine optimization are considered which directly impact the design of the baseline thrust chamber. Four major areas of the power cycle optimization are emphasized: main turbine arrangement; cycle engine source; high pressure pump design; and boost pump drive.

Prechamber Compression-Ignition Engine Performance

NASA Technical Reports Server (NTRS)

Moore, Charles S; Collins, John H , Jr

1938-01-01

Single-cylinder compression-ignition engine tests were made to investigate the performance characteristics of prechamber type of cylinder head. Certain fundamental variables influencing engine performance -- clearance distribution, size, shape, and direction of the passage connecting the cylinder and prechamber, shape of prechamber, cylinder clearance, compression ratio, and boosting -- were independently tested. Results of motoring and of power tests, including several typical indicator cards, are presented.

Dominican Republic: Political and Economic Conditions and Relations with the United States

DTIC Science & Technology

2005-03-08

Killed in Dominican Republic Prison Fire,” The New York Times, March 8, 2008. 8 See Gerardo Reyes, “Esclavos en Paraíso,”El Nuevo Herald, Jan. 9... Perez , “Widespread Blackouts Leave President Scrambling to Boost Power,” Agence France-Presse, Feb. 8, 2000. 13 Jose de Cordoba, “Caribbean Cloud,”Wall

A proposed adaptive step size perturbation and observation maximum power point tracking algorithm based on photovoltaic system modeling

NASA Astrophysics Data System (ADS)

Huang, Yu

Solar energy becomes one of the major alternative renewable energy options for its huge abundance and accessibility. Due to the intermittent nature, the high demand of Maximum Power Point Tracking (MPPT) techniques exists when a Photovoltaic (PV) system is used to extract energy from the sunlight. This thesis proposed an advanced Perturbation and Observation (P&O) algorithm aiming for relatively practical circumstances. Firstly, a practical PV system model is studied with determining the series and shunt resistances which are neglected in some research. Moreover, in this proposed algorithm, the duty ratio of a boost DC-DC converter is the object of the perturbation deploying input impedance conversion to achieve working voltage adjustment. Based on the control strategy, the adaptive duty ratio step size P&O algorithm is proposed with major modifications made for sharp insolation change as well as low insolation scenarios. Matlab/Simulink simulation for PV model, boost converter control strategy and various MPPT process is conducted step by step. The proposed adaptive P&O algorithm is validated by the simulation results and detail analysis of sharp insolation changes, low insolation condition and continuous insolation variation.

An Optimal Control Strategy for DC Bus Voltage Regulation in Photovoltaic System with Battery Energy Storage

PubMed Central

Daud, Muhamad Zalani; Mohamed, Azah; Hannan, M. A.

2014-01-01

This paper presents an evaluation of an optimal DC bus voltage regulation strategy for grid-connected photovoltaic (PV) system with battery energy storage (BES). The BES is connected to the PV system DC bus using a DC/DC buck-boost converter. The converter facilitates the BES power charge/discharge to compensate for the DC bus voltage deviation during severe disturbance conditions. In this way, the regulation of DC bus voltage of the PV/BES system can be enhanced as compared to the conventional regulation that is solely based on the voltage-sourced converter (VSC). For the grid side VSC (G-VSC), two control methods, namely, the voltage-mode and current-mode controls, are applied. For control parameter optimization, the simplex optimization technique is applied for the G-VSC voltage- and current-mode controls, including the BES DC/DC buck-boost converter controllers. A new set of optimized parameters are obtained for each of the power converters for comparison purposes. The PSCAD/EMTDC-based simulation case studies are presented to evaluate the performance of the proposed optimized control scheme in comparison to the conventional methods. PMID:24883374

An optimal control strategy for DC bus voltage regulation in photovoltaic system with battery energy storage.

PubMed

Daud, Muhamad Zalani; Mohamed, Azah; Hannan, M A

2014-01-01

This paper presents an evaluation of an optimal DC bus voltage regulation strategy for grid-connected photovoltaic (PV) system with battery energy storage (BES). The BES is connected to the PV system DC bus using a DC/DC buck-boost converter. The converter facilitates the BES power charge/discharge to compensate for the DC bus voltage deviation during severe disturbance conditions. In this way, the regulation of DC bus voltage of the PV/BES system can be enhanced as compared to the conventional regulation that is solely based on the voltage-sourced converter (VSC). For the grid side VSC (G-VSC), two control methods, namely, the voltage-mode and current-mode controls, are applied. For control parameter optimization, the simplex optimization technique is applied for the G-VSC voltage- and current-mode controls, including the BES DC/DC buck-boost converter controllers. A new set of optimized parameters are obtained for each of the power converters for comparison purposes. The PSCAD/EMTDC-based simulation case studies are presented to evaluate the performance of the proposed optimized control scheme in comparison to the conventional methods.

Assessment of Cultivation Factors that Affect Biomass and Geraniol Production in Transgenic Tobacco Cell Suspension Cultures

PubMed Central

Vasilev, Nikolay; Schmitz, Christian; Grömping, Ulrike; Fischer, Rainer; Schillberg, Stefan

2014-01-01

A large-scale statistical experimental design was used to determine essential cultivation parameters that affect biomass accumulation and geraniol production in transgenic tobacco (Nicotiana tabacum cv. Samsun NN) cell suspension cultures. The carbohydrate source played a major role in determining the geraniol yield and factors such as filling volume, inoculum size and light were less important. Sucrose, filling volume and inoculum size had a positive effect on geraniol yield by boosting growth of plant cell cultures whereas illumination of the cultures stimulated the geraniol biosynthesis. We also found that the carbohydrates sucrose and mannitol showed polarizing effects on biomass and geraniol accumulation. Factors such as shaking frequency, the presence of conditioned medium and solubilizers had minor influence on both plant cell growth and geraniol content. When cells were cultivated under the screened conditions for all the investigated factors, the cultures produced ∼5.2 mg/l geraniol after 12 days of cultivation in shaking flasks which is comparable to the yield obtained in microbial expression systems. Our data suggest that industrial experimental designs based on orthogonal arrays are suitable for the selection of initial cultivation parameters prior to the essential medium optimization steps. Such designs are particularly beneficial in the early optimization steps when many factors must be screened, increasing the statistical power of the experiments without increasing the demand on time and resources. PMID:25117009

Assessment of cultivation factors that affect biomass and geraniol production in transgenic tobacco cell suspension cultures.

PubMed

Vasilev, Nikolay; Schmitz, Christian; Grömping, Ulrike; Fischer, Rainer; Schillberg, Stefan

2014-01-01

A large-scale statistical experimental design was used to determine essential cultivation parameters that affect biomass accumulation and geraniol production in transgenic tobacco (Nicotiana tabacum cv. Samsun NN) cell suspension cultures. The carbohydrate source played a major role in determining the geraniol yield and factors such as filling volume, inoculum size and light were less important. Sucrose, filling volume and inoculum size had a positive effect on geraniol yield by boosting growth of plant cell cultures whereas illumination of the cultures stimulated the geraniol biosynthesis. We also found that the carbohydrates sucrose and mannitol showed polarizing effects on biomass and geraniol accumulation. Factors such as shaking frequency, the presence of conditioned medium and solubilizers had minor influence on both plant cell growth and geraniol content. When cells were cultivated under the screened conditions for all the investigated factors, the cultures produced ∼ 5.2 mg/l geraniol after 12 days of cultivation in shaking flasks which is comparable to the yield obtained in microbial expression systems. Our data suggest that industrial experimental designs based on orthogonal arrays are suitable for the selection of initial cultivation parameters prior to the essential medium optimization steps. Such designs are particularly beneficial in the early optimization steps when many factors must be screened, increasing the statistical power of the experiments without increasing the demand on time and resources.

MMIC HEMT Power Amplifier for 140 to 170 GHz

NASA Technical Reports Server (NTRS)

Samoska, Lorene; Radisic, Vesna; Ngo, Catherine; Janke, Paul; Hu, Ming; Micovic, Miro

2003-01-01

A three-stage monolithic microwave integrated circuit (MMIC) power amplifier that features high-electron-mobility transistors (HEMTs) as gain elements is reviewed. This amplifier is designed to operate in the frequency range of 140 to 170 GHz, which contains spectral lines of several atmospheric molecular species plus subharmonics of other such spectral lines. Hence, this amplifier could serve as a prototype of amplifiers to be incorporated into heterodyne radiometers used in atmospheric science. The original intended purpose served by this amplifier is to boost the signal generated by a previously developed 164-GHz MMIC HEMT doubler and drive a 164-to-328-GHz doubler to provide a few milliwatts of power at 328 GHz.

Power counting and modes in SCET

NASA Astrophysics Data System (ADS)

Goerke, Raymond; Luke, Michael

2018-02-01

We present a formulation of soft-collinear effective theory (SCET) in the two-jet sector as a theory of decoupled sectors of QCD coupled to Wilson lines. The formulation is manifestly boost-invariant, does not require the introduction of ultrasoft modes at the hard matching scale Q, and has manifest power counting in inverse powers of Q. The spurious infrared divergences which arise in SCET when ultrasoft modes are not included in loops disappear when the overlap between the sectors is correctly subtracted, in a manner similar to the familiar zero-bin subtraction of SCET. We illustrate this approach by analyzing deep inelastic scattering in the endpoint region in SCET and comment on other applications.

Minimal groups increase young children's motivation and learning on group-relevant tasks.

PubMed

Master, Allison; Walton, Gregory M

2013-01-01

Three experiments (N = 130) used a minimal group manipulation to show that just perceived membership in a social group boosts young children's motivation for and learning from group-relevant tasks. In Experiment 1, 4-year-old children assigned to a minimal "puzzles group" persisted longer on a challenging puzzle than children identified as the "puzzles child" or children in a control condition. Experiment 2 showed that this boost in motivation occurred only when the group was associated with the task. In Experiment 3, children assigned to a minimal group associated with word learning learned more words than children assigned an analogous individual identity. The studies demonstrate that fostering shared motivations may be a powerful means by which to shape young children's academic outcomes. © 2012 The Authors. Child Development © 2012 Society for Research in Child Development, Inc.

A novel power converter for photovoltaic applications

NASA Astrophysics Data System (ADS)

Yuvarajan, S.; Yu, Dachuan; Xu, Shanguang

A simple and economical power conditioner to convert the power available from solar panels into 60 Hz ac voltage is described. The raw dc voltage from the solar panels is converted to a regulated dc voltage using a boost converter and a large capacitor and the dc output is then converted to 60 Hz ac using a bridge inverter. The ratio between the load current and the short-circuit current of a PV panel at maximum power point is nearly constant for different insolation (light) levels and this property is utilized in designing a simple maximum power point tracking (MPPT) controller. The controller includes a novel arrangement for sensing the short-circuit current without disturbing the operation of the PV panel and implementing MPPT. The switching losses in the inverter are reduced by using snubbers. The results obtained on an experimental converter are presented.

Diesel Engine Waste Heat Recovery Utilizing Electric Turbocompound Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hopman, Ulrich,; Kruiswyk, Richard W.

2005-07-05

Caterpillar's Technology & Solutions Division conceived, designed, built and tested an electric turbocompound system for an on-highway heavy-duty truck engine. The heart of the system is a unique turbochargerr with an electric motor/generator mounted on the shaft between turbine and compressor wheels. When the power produced by the turbocharger turbine exceeds the power of the compressor, the excess power is converted to electrical power by the generator on the turbo shaft; that power is then used to help turn the crankshaft via an electric motor mounted in the engine flywheel housing. The net result is an improvement in engine fuelmore » economy. The electric turbocompound system provides added control flexibility because it is capable of varying the amount of power extracted from the exhaust gases, thus allowing for control of engine boost. The system configuration and design, turbocharger features, control system development, and test results are presented.« less

A Multi-institutional Study of Factors Influencing the Use of Stereotactic Radiosurgery for Brain Metastases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hodgson, David C., E-mail: David.Hodgson@rmp.uhn.on.ca; Department of Radiation Oncology, University of Toronto, Toronto, Ontario; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario

2013-02-01

Purpose: Stereotactic radiosurgery (SRS) for brain metastases is a relatively well-studied technology with established guidelines regarding patient selection, although its implementation is technically complex. We evaluated the extent to which local availability of SRS affected the treatment of patients with brain metastases. Methods and Materials: We identified 3030 patients who received whole-brain radiation therapy (WBRT) for brain metastases in 1 of 7 cancer centers in Ontario. Clinical data were abstracted for a random sample of 973 patients. Logistic regression analyses were performed to identify factors associated with the use of SRS as a boost within 4 months following WBRT ormore » at any time following WBRT. Results: Of 898 patients eligible for analysis, SRS was provided to 70 (7.8%) patients at some time during the course of their disease and to 34 (3.8%) patients as a boost following WBRT. In multivariable analyses, factors significantly associated with the use of SRS boost following WBRT were fewer brain metastases (odds ratio [OR] = 6.50), controlled extracranial disease (OR = 3.49), age (OR = 0.97 per year of advancing age), and the presence of an on-site SRS program at the hospital where WBRT was given (OR = 12.34; all P values were <.05). Similarly, availability of on-site SRS was the factor most predictive of the use of SRS at any time following WBRT (OR = 5.98). Among patients with 1-3 brain metastases, good/fair performance status, and no evidence of active extracranial disease, SRS was provided to 40.3% of patients who received WBRT in a hospital that had an on-site SRS program vs 3.0% of patients who received WBRT at a hospital without SRS (P<.01). Conclusions: The availability of on-site SRS is the factor most strongly associated with the provision of this treatment to patients with brain metastases and appears to be more influential than accepted clinical eligibility factors.« less

Techno-Economic Analysis of Integration of Low-Temperature Geothermal Resources for Coal-Fired Power Plants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bearden, Mark D.; Davidson, Casie L.; Horner, Jacob A.

Presented here are the results of a techno-economic (TEA) study of the potential for coupling low-grade geothermal resources to boost the electrical output from coal-fired power plants. This study includes identification of candidate 500 MW subcritical coal-fired power plants in the continental United States, followed by down-selection and characterization of the North Valmy generating station, a Nevada coal-fired plant. Based on site and plant characteristics, ASPEN Plus models were designed to evaluate options to integrate geothermal resources directly into existing processes at North Valmy. Energy outputs and capital costing are presented for numerous hybrid strategies, including integration with Organic Rankinemore » Cycles (ORCs), which currently represent the primary technology for baseload geothermal power generation.« less

The rectenna design on contact lens for wireless powering of the active intraocular pressure monitoring system.

PubMed

Cheng, H W; Jeng, B M; Chen, C Y; Huang, H Y; Chiou, J C; Luo, C H

2013-01-01

This paper proposed a wireless power harvesting system with micro-electro-mechanical-systems (MEMS) fabrication for noninvasive intraocular pressure (IOP) measurement on soft contact lens substructure. The power harvesting IC consists of a loop antenna, an impedance matching network and a rectifier. The proposed IC has been designed and fabricated by CMOS 0.18 um process that operates at the ISM band of 5.8 GHz. The antenna and the power harvesting IC would be bonded together by using flip chip bonding technologies without extra wire interference. The circuit utilized an impedance transformation circuit to boost the input RF signal that improves the circuit performance. The proposed design achieves an RF-to-DC conversion efficiency of 35% at 5.8 GHz.

CMOS Ultralow Power Brain Signal Acquisition Front-Ends: Design and Human Testing.

PubMed

Karimi-Bidhendi, Alireza; Malekzadeh-Arasteh, Omid; Lee, Mao-Cheng; McCrimmon, Colin M; Wang, Po T; Mahajan, Akshay; Liu, Charles Yu; Nenadic, Zoran; Do, An H; Heydari, Payam

2017-08-01

Two brain signal acquisition (BSA) front-ends incorporating two CMOS ultralow power, low-noise amplifier arrays and serializers operating in mosfet weak inversion region are presented. To boost the amplifier's gain for a given current budget, cross-coupled-pair active load topology is used in the first stages of these two amplifiers. These two BSA front-ends are fabricated in 130 and 180 nm CMOS processes, occupying 5.45 mm 2 and 0.352 mm 2 of die areas, respectively (excluding pad rings). The CMOS 130-nm amplifier array is comprised of 64 elements, where each amplifier element consumes 0.216 μW from 0.4 V supply, has input-referred noise voltage (IRNoise) of 2.19 μV[Formula: see text] corresponding to a power efficiency factor (PEF) of 11.7, and occupies 0.044 mm 2 of die area. The CMOS 180 nm amplifier array employs 4 elements, where each element consumes 0.69 μW from 0.6 V supply with IRNoise of 2.3 μV[Formula: see text] (corresponding to a PEF of 31.3) and 0.051 mm 2 of die area. Noninvasive electroencephalographic and invasive electrocorticographic signals were recorded real time directly on able-bodied human subjects, showing feasibility of using these analog front-ends for future fully implantable BSA and brain- computer interface systems.

Drive for consumption, craving, and connectivity in the visual cortex during the imagery of desired food.

PubMed

Bullins, Jessica; Laurienti, Paul J; Morgan, Ashley R; Norris, James; Paolini, Brielle M; Rejeski, W Jack

2013-01-01

There is considerable interest in understanding food cravings given the obesogenic environment of Western Society. In this paper we examine how the imagery of palatable foods affects cravings and functional connectivity in the visual cortex for people who differ on the power of food scale (PFS). Fourteen older, overweight/obese adults came to our laboratory on two different occasions. Both times they ate a controlled breakfast meal and then were restricted from eating for 2.5 h prior to scanning. On 1 day they consumed a BOOST(®) liquid meal after the period of food restriction, whereas on the other day they only consumed water (NO BOOST(®) condition). After these manipulations, they had an fMRI scan in which they were asked to image both neutral objects and their favorite snack foods; they also completed visual analog scales for craving, hunger, and the vividness of the imagery experiences. Irrespective of the BOOST(®) manipulation, we observed marked increases in food cravings when older, overweight/obese adults created images of favorite foods in their minds as opposed to creating an image of neutral objects; however, the increase in food craving following the imagery of desired food was more pronounced among those scoring high than low on the PFS. Furthermore, local efficiency within the visual cortex when imaging desired food was higher for those scoring high as compared to low on the PFS. The active imagery of desired foods seemed to have overpowered the BOOST(®) manipulation when evaluating connectivity in the visual cortex.

The key particle and quark energy equality E W + E Z = E top

NASA Astrophysics Data System (ADS)

Mac Gregor, Malcolm H.

2017-11-01

Precision Tevatron and Linear Hadron Collider measurements at Fermilab and CERN have revealed the numerically accurate mass equality W + Z = t. This equality between two gauge bosons ( gb) and the top quark t is only valid if reinterpreted as an energy equality, where E = mc 2, since energy is a shared property of particles and quarks. The experimental data indicate that the LHC particle excitation energy is quantized in the form of gauge boson energy packets E gb , which are created by factor-of-137 proton-quark energy increases denoted as α- boosts, where α 1/137 is the fine structure constant. These α-boosts occur during the rare head-on quark-quark collisions in the proton beams. The α-boost energy quantization mechanism also occurs in low-energy electron-positron boson and fermion particle production channels, where it generates E b and E f energy packets. These α-boost energy channels link together coherently, as demonstrated by the accurate top quark energy equation E top = (18/α2) E electron. Particle production energy equations are derived which combine to create an overall energy pattern that accurately reproduces the energies of the ( u, d), s, c, b, t fermion constituent quarks, the µ and τ leptons, and the proton.

Assessing and comparison of different machine learning methods in parent-offspring trios for genotype imputation.

PubMed

Mikhchi, Abbas; Honarvar, Mahmood; Kashan, Nasser Emam Jomeh; Aminafshar, Mehdi

2016-06-21

Genotype imputation is an important tool for prediction of unknown genotypes for both unrelated individuals and parent-offspring trios. Several imputation methods are available and can either employ universal machine learning methods, or deploy algorithms dedicated to infer missing genotypes. In this research the performance of eight machine learning methods: Support Vector Machine, K-Nearest Neighbors, Extreme Learning Machine, Radial Basis Function, Random Forest, AdaBoost, LogitBoost, and TotalBoost compared in terms of the imputation accuracy, computation time and the factors affecting imputation accuracy. The methods employed using real and simulated datasets to impute the un-typed SNPs in parent-offspring trios. The tested methods show that imputation of parent-offspring trios can be accurate. The Random Forest and Support Vector Machine were more accurate than the other machine learning methods. The TotalBoost performed slightly worse than the other methods.The running times were different between methods. The ELM was always most fast algorithm. In case of increasing the sample size, the RBF requires long imputation time.The tested methods in this research can be an alternative for imputation of un-typed SNPs in low missing rate of data. However, it is recommended that other machine learning methods to be used for imputation. Copyright © 2016 Elsevier Ltd. All rights reserved.

Stimulus Scale Seen as Issue: K-12 Funding Boost Could Shift Federal-State Balance of Power

ERIC Educational Resources Information Center

Klein, Alyson

2009-01-01

The sheer scale of the new education aid envisioned under the economic-stimulus package now pending in Congress is forcing educators and state officials to consider how they would absorb that funding and how it could transform--or distort--school programs at the local level. Officials from governors' mansions on down are generally pleased at the…

German Day: A Practical Guide to Connecting High School and Post-Secondary Programs

ERIC Educational Resources Information Center

Howards, Alyssa; Rinner, Susanne; Gulewich, Beth

2018-01-01

An annual German Day event can be a powerful tool to motivate students, increase visibility of state and local German programs, and, ultimately, boost enrollments. However, it can also be a daunting undertaking that is often orchestrated by a single person. This article offers a user guide that can help others plan their own German Day, be it a…

Herpes Zoster Risk Reduction through Exposure to Chickenpox Patients: A Systematic Multidisciplinary Review

PubMed Central

Ogunjimi, Benson; Van Damme, Pierre; Beutels, Philippe

2013-01-01

Varicella-zoster virus (VZV) causes chickenpox and may subsequently reactivate to cause herpes zoster later in life. The exogenous boosting hypothesis states that re-exposure to circulating VZV can inhibit VZV reactivation and consequently also herpes zoster in VZV-immune individuals. Using this hypothesis, mathematical models predicted widespread chickenpox vaccination to increase herpes zoster incidence over more than 30 years. Some countries have postponed universal chickenpox vaccination, at least partially based on this prediction. After a systematic search and selection procedure, we analyzed different types of exogenous boosting studies. We graded 13 observational studies on herpes zoster incidence after widespread chickenpox vaccination, 4 longitudinal studies on VZV immunity after re-exposure, 9 epidemiological risk factor studies, 7 mathematical modeling studies as well as 7 other studies. We conclude that exogenous boosting exists, although not for all persons, nor in all situations. Its magnitude is yet to be determined adequately in any study field. PMID:23805224

Improved Reweighting of Accelerated Molecular Dynamics Simulations for Free Energy Calculation.

PubMed

Miao, Yinglong; Sinko, William; Pierce, Levi; Bucher, Denis; Walker, Ross C; McCammon, J Andrew

2014-07-08

Accelerated molecular dynamics (aMD) simulations greatly improve the efficiency of conventional molecular dynamics (cMD) for sampling biomolecular conformations, but they require proper reweighting for free energy calculation. In this work, we systematically compare the accuracy of different reweighting algorithms including the exponential average, Maclaurin series, and cumulant expansion on three model systems: alanine dipeptide, chignolin, and Trp-cage. Exponential average reweighting can recover the original free energy profiles easily only when the distribution of the boost potential is narrow (e.g., the range ≤20 k B T) as found in dihedral-boost aMD simulation of alanine dipeptide. In dual-boost aMD simulations of the studied systems, exponential average generally leads to high energetic fluctuations, largely due to the fact that the Boltzmann reweighting factors are dominated by a very few high boost potential frames. In comparison, reweighting based on Maclaurin series expansion (equivalent to cumulant expansion on the first order) greatly suppresses the energetic noise but often gives incorrect energy minimum positions and significant errors at the energy barriers (∼2-3 k B T). Finally, reweighting using cumulant expansion to the second order is able to recover the most accurate free energy profiles within statistical errors of ∼ k B T, particularly when the distribution of the boost potential exhibits low anharmonicity (i.e., near-Gaussian distribution), and should be of wide applicability. A toolkit of Python scripts for aMD reweighting "PyReweighting" is distributed free of charge at http://mccammon.ucsd.edu/computing/amdReweighting/.

Improved Reweighting of Accelerated Molecular Dynamics Simulations for Free Energy Calculation

PubMed Central

2015-01-01

Accelerated molecular dynamics (aMD) simulations greatly improve the efficiency of conventional molecular dynamics (cMD) for sampling biomolecular conformations, but they require proper reweighting for free energy calculation. In this work, we systematically compare the accuracy of different reweighting algorithms including the exponential average, Maclaurin series, and cumulant expansion on three model systems: alanine dipeptide, chignolin, and Trp-cage. Exponential average reweighting can recover the original free energy profiles easily only when the distribution of the boost potential is narrow (e.g., the range ≤20kBT) as found in dihedral-boost aMD simulation of alanine dipeptide. In dual-boost aMD simulations of the studied systems, exponential average generally leads to high energetic fluctuations, largely due to the fact that the Boltzmann reweighting factors are dominated by a very few high boost potential frames. In comparison, reweighting based on Maclaurin series expansion (equivalent to cumulant expansion on the first order) greatly suppresses the energetic noise but often gives incorrect energy minimum positions and significant errors at the energy barriers (∼2–3kBT). Finally, reweighting using cumulant expansion to the second order is able to recover the most accurate free energy profiles within statistical errors of ∼kBT, particularly when the distribution of the boost potential exhibits low anharmonicity (i.e., near-Gaussian distribution), and should be of wide applicability. A toolkit of Python scripts for aMD reweighting “PyReweighting” is distributed free of charge at http://mccammon.ucsd.edu/computing/amdReweighting/. PMID:25061441

Fuzzy logic, PSO based fuzzy logic algorithm and current controls comparative for grid-connected hybrid system

NASA Astrophysics Data System (ADS)

Borni, A.; Abdelkrim, T.; Zaghba, L.; Bouchakour, A.; Lakhdari, A.; Zarour, L.

2017-02-01

In this paper the model of a grid connected hybrid system is presented. The hybrid system includes a variable speed wind turbine controlled by aFuzzy MPPT control, and a photovoltaic generator controlled with PSO Fuzzy MPPT control to compensate the power fluctuations caused by the wind in a short and long term, the inverter currents injected to the grid is controlled by a decoupled PI current control. In the first phase, we start by modeling of the conversion system components; the wind system is consisted of a turbine coupled to a gearless permanent magnet generator (PMG), the AC/DC and DC-DC (Boost) converter are responsible to feed the electric energy produced by the PMG to the DC-link. The solar system consists of a photovoltaic generator (GPV) connected to a DC/DC boost converter controlled by a PSO fuzzy MPPT control to extract at any moment the maximum available power at the GPV terminals, the system is based on maximum utilization of both of sources because of their complementary. At the end. The active power reached to the DC-link is injected to the grid through a DC/AC inverter, this function is achieved by controlling the DC bus voltage to keep it constant and close to its reference value, The simulation studies have been performed using Matlab/Simulink. It can be concluded that a good control system performance can be achieved.

Performance analysis of ‘Perturb and Observe’ and ‘Incremental Conductance’ MPPT algorithms for PV system

NASA Astrophysics Data System (ADS)

Lodhi, Ehtisham; Lodhi, Zeeshan; Noman Shafqat, Rana; Chen, Fieda

2017-07-01

Photovoltaic (PV) system usually employed The Maximum power point tracking (MPPT) techniques for increasing its efficiency. The performance of the PV system perhaps boosts by controlling at its apex point of power, in this way maximal power can be given to load. The proficiency of a PV system usually depends upon irradiance, temperature and array architecture. PV array shows a non-linear style for V-I curve and maximal power point on V-P curve also varies with changing environmental conditions. MPPT methods grantees that a PV module is regulated at reference voltage and to produce entire usage of the maximal output power. This paper gives analysis between two widely employed Perturb and Observe (P&O) and Incremental Conductance (INC) MPPT techniques. Their performance is evaluated and compared through theoretical analysis and digital simulation on the basis of response time and efficiency under varying irradiance and temperature condition using Matlab/Simulink.

10 W single-mode Er/Yb co-doped all-fiber amplifier with suppressed Yb-ASE

NASA Astrophysics Data System (ADS)

Sobon, G.; Sliwinska, D.; Abramski, K. M.; Kaczmarek, P.

2014-02-01

In this work we demonstrate a single-frequency, single-mode all-fiber master oscillator power amplifier (MOPA) source, based on erbium-ytterbium co-doped double-clad fiber emitting 10 W of continuous wave power at 1565 nm. In the power amplifier stage, the amplified spontaneous emission from Yb3+ ions (Yb-ASE) is forced to recirculate in a loop resonator in order to provide stable lasing at 1060 nm. The generated signal acts as an additional pump source for the amplifier and is reabsorbed by the Yb3+ ions in the active fiber, allowing an increase in the efficiency and boosting the output power. The feedback loop also protects the amplifier from parasitic lasing or self-pulsing at a wavelength of 1 μm. This allows one to significantly scale the output power in comparison to a conventional setup without any Yb-ASE control.

Integration of power over fiber on RoF systems in different scenarios

NASA Astrophysics Data System (ADS)

Vázquez, C.; Montero, D. S.; Pinzón, P. J.; López-Cardona, J. D.; Contreras, P.; Tapetado, A.

2017-01-01

Future high capacity of the 5th Generation radio environment will boost transport networks to be adapted. The high bandwidth, together with stringent delay and jitter requirements, make dedicated optical connectivity a preferred solution for fronthaul. Those Radio Access Networks apart from higher capacity and lower latency should have higher energy efficiency. In order to cover this aspect, power over fiber has been pointed out as a key technology for that purpose having in mind that control plane will be centralized on future Cloud RAN and that sometimes Remote Radio Heads should be deployed in places lacking external power supply in order to fulfill the desired coverage. In this paper, different scenarios on potential demanding environments of power over fiber on Radio over Fiber systems such as automotive, in-house and remote mobile fronthaul will be discussed. Some tests on power over fiber systems based on different optical fibers are provided.

Simultaneous integrated intensity-modulated radiotherapy boost for locally advanced gynecological cancer: Radiobiological and dosimetric considerations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guerrero, Mariana; Li, X. Allen; Ma Lijun

2005-07-01

Purpose: Whole-pelvis irradiation (WPI) followed by a boost to the tumor site is the standard of practice for the radiotherapeutic management of locally advanced gynecologic cancers. The boost is frequently administered by use of brachytherapy or, occasionally, external-beam radiotherapy (EBRT) when brachytherapy does not provide sufficient coverage because of the size of the tumor or the geometry of the patient. In this work, we propose using an intensity-modulated radiotherapy (IMRT) simultaneous integrated boost (SIB), which is a single-phase process, to replace the conventional two-phase process involving WPI plus a boost. Radiobiological modeling is used to design appropriate regimens for themore » IMRT SIB. To demonstrate feasibility, a dosimetric study is carried out on an example patient. Methods and Materials: The standard linear-quadratic (LQ) model is used to calculate the biologically effective dose (BED) and equivalent uniform dose (EUD). A series of regimens that are biologically equivalent to those conventional two-phase treatments is calculated for the proposed SIB. A commercial inverse planning system (Corvus) was used to generate IMRT SIB plans for a sample patient case that used the newly designed fractionations. The dose-volume histogram (DVH) and EUD of both the target and normal structures for conventional treatments and the SIB are compared. A sparing factor was introduced to characterize the sparing of normal structures. Results: Fractionation regimes that are equivalent to the conventional treatments and are suitable for the IMRT SIB are deduced. For example, a SIB plan with 25 x 3.1 Gy (77.5 Gy) to a tumor is equivalent to a conventional treatment of EBRT of 45 Gy to the whole pelvis in 25 fractions plus a high-dose rate (HDR) brachytherapy boost with 30 Gy in 5 fractions. The normal tissue BED is found to be lower for the SIB plan than for the whole-pelvis plus HDR scheme when a sparing factor for the critical structures is considered. This finding suggests that the IMRT SIB has a better therapeutic ratio. Three IMRT SIB plans with 25 x 1.8 Gy to the pelvic nodes and 25 x 2.4 Gy (60 Gy), 25 x 2.8 Gy (70 Gy), and 25 x 3.2 Gy (80 Gy) to the tumor site were generated for the example patient case. The target coverage ranged from 94% to 95.5%. The sparing of bladder and rectum is significantly improved with the 60 to 70 Gy SIB treatments, as compared with the conventional treatments. The proposed SIB treatment can reduce the treatment time to 5 weeks. Conclusions: An IMRT simultaneous integrated boost to replace the conventional two-phase treatments (whole pelvic irradiation followed by brachytherapy or EBRT boost) is radiobiologically and dosimetricaly feasible for locally advanced gynecological cancers that may not be amenable to brachytherapy for anatomic or medical reasons. In addition to its shorter treatment time, the proposed IMRT SIB can provide significant sparing to normal structures, which offers potential for dose escalation. Issues such as organ motion and changing anatomy as tumor responds still must be addressed.« less

Feeling connected to younger versus older selves: the asymmetric impact of life stage orientation.

PubMed

O'Brien, Ed

2015-01-01

The concept of life-stage orientation is proposed. Youth is a period of time characterised by strong feelings and emotions, but weak reasoning and cognitive skill. Conversely, adulthood is characterised by strong rationality, but weak emotionality. Two studies revealed that merely bringing these concepts to mind changes real-time feelings and behaviour. Participants who were instructed to act like their "adult" selves exhibited greater self-control in a cold pressor test than control participants and those who acted like their "youth" selves (Experiment 1). However, being induced to feel connected to youth enhanced enjoyment for fun videos (Experiment 2). Hence, the extent to which people are oriented towards youth versus adulthood has asymmetric costs and benefits for the present. Connecting to youth boosts experiential capacities (in this case, enjoying oneself) at the cost of agency, whereas connecting to adulthood boosts agentic capacities (in this case, exerting will-power) at the cost of experience.

The Decoy Effect as a Nudge: Boosting Hand Hygiene With a Worse Option.

PubMed

Li, Meng; Sun, Yan; Chen, Hui

2018-05-01

This article provides the first test of the decoy effect as a nudge to influence real-world behavior. The decoy effect is the phenomenon that an additional but worse option can boost the appeal of an existing option. It has been widely demonstrated in hypothetical choices, but its usefulness in real-world settings has been subject to debate. In three longitudinal experiments in food-processing factories, we tested two decoy sanitation options that were worse than the existing sanitizer spray bottle. Results showed that the presence of a decoy, but not an additional copy of the original sanitizer bottle in a different color, drastically increased food workers' hand sanitizer use from the original sanitizer bottle and, consequently, improved workers' passing rate in hand sanitary tests from 60% to 70% to above 90% for 20 days. These findings indicate that the decoy effect can be a powerful nudge technique to influence real-world behavior.

Laser Boost of a Small Interstellar Ram Jet to Obtain Operational Velocity. Implications for the DM Rocket/Ram Jet Model

NASA Astrophysics Data System (ADS)

Walcott Beckwith, Andrew

2010-05-01

In other conference research papers, Beckwith obtained a maximum DM mass/energy value of up to 5 TeV, as opposed to 400 GeV for DM, which may mean more convertible power for a dark matter ram jet. The consequences are from assuming that axions are CDM, and KK gravitons are for WDM, then ρWarm-Dark-Matter would dominate not only structure formation in early universe formation, but would also influence the viability of the DM ram jet applications for interstellar travel. The increase in convertible DM mass makes the ram jet a conceivable option. This paper in addition to describing the scientific issues leading to that 5 TeV mass for DM also what are necessary and sufficient laser boost systems which would permit a ram net to become operational.

Lunar Orbiter 4 - Photographic Mission Summary. Volume 1

NASA Technical Reports Server (NTRS)

1968-01-01

Photographic summary report of Lunar Orbiter 4 mission. The fourth of five Lunar Orbiter spacecraft was successfully launched from Launch Complex 13 at the Air Force Eastern Test Range by an Atlas-Agena launch vehicle at 22:25 GMT on May 4, 1967. Tracking data from the Cape Kennedy and Grand Bahama tracking stations were used to control and guide the launch vehicle during Atlas powered flight. The Agena-spacecraft combination was boosted to the proper coast ellipse by the Atlas booster prior to separation. Final maneuvering and acceleration to the velocity required to maintain the 100-nauticalmile- altitude Earth orbit was controlled by the preset on-board Agena computer. In addition, the Agena computer determined the maneuver and engine-burn period required to inject the spacecraft on the cislunar trajectory 20 minutes after launch. Tracking data from the downrange stations and the Johannesburg, South Africa station were used to monitor the boost trajectory.

Cosmic string detection with tree-based machine learning

NASA Astrophysics Data System (ADS)

Vafaei Sadr, A.; Farhang, M.; Movahed, S. M. S.; Bassett, B.; Kunz, M.

2018-07-01

We explore the use of random forest and gradient boosting, two powerful tree-based machine learning algorithms, for the detection of cosmic strings in maps of the cosmic microwave background (CMB), through their unique Gott-Kaiser-Stebbins effect on the temperature anisotropies. The information in the maps is compressed into feature vectors before being passed to the learning units. The feature vectors contain various statistical measures of the processed CMB maps that boost cosmic string detectability. Our proposed classifiers, after training, give results similar to or better than claimed detectability levels from other methods for string tension, Gμ. They can make 3σ detection of strings with Gμ ≳ 2.1 × 10-10 for noise-free, 0.9'-resolution CMB observations. The minimum detectable tension increases to Gμ ≳ 3.0 × 10-8 for a more realistic, CMB S4-like (II) strategy, improving over previous results.

Lunar Orbiter 5. Photographic Mission Summary. Volume 1

NASA Technical Reports Server (NTRS)

1968-01-01

Selected photographs and mission summary of Lunar Orbiter 5. The last of five Lunar Orbiter spacecraft was successfully launched from Launch Complex 13 at the Air Force Eastern Test Range by an Atlas-Agena launch vehicle at 22:33 GMT on August 1, 1967. Tracking data from the Cape Kennedy and Grand Bahama tracking stations were used to control and guide the launch vehicle during Atlas powered flight. The Agena-spacecraft combination was boosted to the proper coast ellipse by the Atlas booster prior to separation. Final maneuvering and acceleration to the velocity required to maintain the 100-nautical-mile-altitude Earth orbit were controlled by the preset on-board Agena computer. In addition, the Agena computer determined the maneuver and engine-bum period required to inject the spacecraft on the cislunar trajectory about 33 minutes after launch. Tracking data from the downrange stations and the Johannesburg, South Africa station were used to monitor the boost trajectory.

Cosmic String Detection with Tree-Based Machine Learning

NASA Astrophysics Data System (ADS)

Vafaei Sadr, A.; Farhang, M.; Movahed, S. M. S.; Bassett, B.; Kunz, M.

2018-05-01

We explore the use of random forest and gradient boosting, two powerful tree-based machine learning algorithms, for the detection of cosmic strings in maps of the cosmic microwave background (CMB), through their unique Gott-Kaiser-Stebbins effect on the temperature anisotropies. The information in the maps is compressed into feature vectors before being passed to the learning units. The feature vectors contain various statistical measures of the processed CMB maps that boost cosmic string detectability. Our proposed classifiers, after training, give results similar to or better than claimed detectability levels from other methods for string tension, Gμ. They can make 3σ detection of strings with Gμ ≳ 2.1 × 10-10 for noise-free, 0.9΄-resolution CMB observations. The minimum detectable tension increases to Gμ ≳ 3.0 × 10-8 for a more realistic, CMB S4-like (II) strategy, improving over previous results.

Hyperpolarized nanodiamond with long spin-relaxation times

NASA Astrophysics Data System (ADS)

Rej, Ewa; Gaebel, Torsten; Boele, Thomas; Waddington, David E. J.; Reilly, David J.

2015-10-01

The use of hyperpolarized agents in magnetic resonance, such as 13C-labelled compounds, enables powerful new imaging and detection modalities that stem from a 10,000-fold boost in signal. A major challenge for the future of the hyperpolarization technique is the inherently short spin-relaxation times, typically <60 s for 13C liquid-state compounds, which limit the time that the signal remains boosted. Here we demonstrate that 1.1% natural abundance 13C spins in synthetic nanodiamond can be hyperpolarized at cryogenic and room temperature without the use of free radicals, and, owing to their solid-state environment, exhibit relaxation times exceeding 1 h. Combined with the already established applications of nanodiamonds in the life sciences as inexpensive fluorescent markers and non-cytotoxic substrates for gene and drug delivery, these results extend the theranostic capabilities of nanoscale diamonds into the domain of hyperpolarized magnetic resonance.

Lunar Orbiter 3 - Photographic Mission Summary

NASA Technical Reports Server (NTRS)

1968-01-01

Systems performance, lunar photography, and launch operations of Lunar Orbiter 3 photographic mission. The third of five Lunar Orbiter spacecraft was successfully launched from Launch Complex 13 at the Air Force Eastern Test Range by an Atlas-Agena launch vehicle at 01:17 GMT on February 5,1967. Tracking data from the Cape Kennedy and Grand Bahama tracking stations were used to control and guide the launch vehicle during Atlas powered flight. The Agena-spacecraft combination was boosted to the proper coast ellipse by the Atlas booster prior to separation. Final 1 maneuvering and acceleration to the velocity required to maintain the 100-nautical-milealtitude Earth orbit was controlled by the preset on-board Agena computer. In addition, the Agena computer determined the maneuver and engine-burn period required to inject the spacecraft on the cislunar trajectory 20 minutes after launch. Tracking data from the downrange stations and the Johannesburg, South Africa station were used to monitor the entire boost trajectory.

Switch failure diagnosis based on inductor current observation for boost converters

NASA Astrophysics Data System (ADS)

Jamshidpour, E.; Poure, P.; Saadate, S.

2016-09-01

Face to the growing number of applications using DC-DC power converters, the improvement of their reliability is subject to an increasing number of studies. Especially in safety critical applications, designing fault-tolerant converters is becoming mandatory. In this paper, a switch fault-tolerant DC-DC converter is studied. First, some of the fastest Fault Detection Algorithms (FDAs) are recalled. Then, a fast switch FDA is proposed which can detect both types of failures; open circuit fault as well as short circuit fault can be detected in less than one switching period. Second, a fault-tolerant converter which can be reconfigured under those types of fault is introduced. Hardware-In-the-Loop (HIL) results and experimental validations are given to verify the validity of the proposed switch fault-tolerant approach in the case of a single switch DC-DC boost converter with one redundant switch.

Efficient Bayesian mixed model analysis increases association power in large cohorts

PubMed Central

Loh, Po-Ru; Tucker, George; Bulik-Sullivan, Brendan K; Vilhjálmsson, Bjarni J; Finucane, Hilary K; Salem, Rany M; Chasman, Daniel I; Ridker, Paul M; Neale, Benjamin M; Berger, Bonnie; Patterson, Nick; Price, Alkes L

2014-01-01

Linear mixed models are a powerful statistical tool for identifying genetic associations and avoiding confounding. However, existing methods are computationally intractable in large cohorts, and may not optimize power. All existing methods require time cost O(MN2) (where N = #samples and M = #SNPs) and implicitly assume an infinitesimal genetic architecture in which effect sizes are normally distributed, which can limit power. Here, we present a far more efficient mixed model association method, BOLT-LMM, which requires only a small number of O(MN)-time iterations and increases power by modeling more realistic, non-infinitesimal genetic architectures via a Bayesian mixture prior on marker effect sizes. We applied BOLT-LMM to nine quantitative traits in 23,294 samples from the Women’s Genome Health Study (WGHS) and observed significant increases in power, consistent with simulations. Theory and simulations show that the boost in power increases with cohort size, making BOLT-LMM appealing for GWAS in large cohorts. PMID:25642633

F1 style MGU-H applied to the turbocharger of a gasoline hybrid electric passenger car

NASA Astrophysics Data System (ADS)

Boretti, Albert

2017-12-01

We consider a turbocharged gasoline direct injection (DI) engine featuring a motor-generator-unit (MGU-H) fitted on the turbocharger shaft. The MGU-H receives or delivers energy to the same energy storage (ES) of the hybrid power unit that comprises a motor-generator unit on the driveline (MGU-K) in addition to the internal combustion engine (ICE). The energy supply from the ES is mostly needed during sharp accelerations to avoid turbo-lag, and to boost torque at low speeds. At low speeds, it also improves the ratio of engine crankshaft power to fuel flow power, as well as the ratio of engine crankshaft plus turbocharger shaft power to fuel flow power. The energy supply to the ES is possible at high speeds and loads, where otherwise the turbine could have been waste gated, and during decelerations. This improves the ratio of engine crankshaft plus turbocharger shaft power to fuel flow power.

Bringing isolated dark matter out of isolation: Late-time reheating and indirect detection

NASA Astrophysics Data System (ADS)

Erickcek, Adrienne L.; Sinha, Kuver; Watson, Scott

2016-09-01

In standard cosmology, the growth of structure becomes significant following matter-radiation equality. In nonthermal histories, where an effectively matter-dominated phase occurs due to scalar oscillations prior to big bang nucleosynthesis, a new scale at smaller wavelengths appears in the matter power spectrum. Density perturbations that enter the horizon during the early matter-dominated era (EMDE) grow linearly with the scale factor prior to the onset of radiation domination, which leads to enhanced inhomogeneity on small scales if dark matter (DM) thermally and kinetically decouples during the EMDE. The microhalos that form from these enhanced perturbations significantly boost the self-annihilation rate for dark matter. This has important implications for indirect detection experiments: the larger annihilation rate may result in observable signals from dark matter candidates that are usually deemed untestable. As a proof of principle, we consider binos in heavy supersymmetry with an intermediate extended Higgs sector and all other superpartners decoupled. We find that these isolated binos, which lie under the neutrino floor, can account for the dark matter relic density and decouple from the standard model early enough to preserve the enhanced small-scale inhomogeneity generated during the EMDE. If early forming microhalos survive as subhalos within larger microhalos, the resulting boost to the annihilation rate for bino dark matter near the pseudoscalar resonance exceeds the upper limit established by Fermi-LAT's observations of dwarf spheroidal galaxies. These DM candidates motivate the N -body simulations required to eliminate uncertainties in the microhalos' internal structure by exemplifying how an EMDE can enable Fermi-LAT to probe isolated dark matter.

PDC-SGB: Prediction of effective drug combinations using a stochastic gradient boosting algorithm.

PubMed

Xu, Qian; Xiong, Yi; Dai, Hao; Kumari, Kotni Meena; Xu, Qin; Ou, Hong-Yu; Wei, Dong-Qing

2017-03-21

Combinatorial therapy is a promising strategy for combating complex diseases by improving the efficacy and reducing the side effects. To facilitate the identification of drug combinations in pharmacology, we proposed a new computational model, termed PDC-SGB, to predict effective drug combinations by integrating biological, chemical and pharmacological information based on a stochastic gradient boosting algorithm. To begin with, a set of 352 golden positive samples were collected from the public drug combination database. Then, a set of 732 dimensional feature vector involving biological, chemical and pharmaceutical information was constructed for each drug combination to describe its properties. To avoid overfitting, the maximum relevance & minimum redundancy (mRMR) method was performed to extract useful ones by removing redundant subsets. Based on the selected features, the three different type of classification algorithms were employed to build the drug combination prediction models. Our results demonstrated that the model based on the stochastic gradient boosting algorithm yield out the best performance. Furthermore, it is indicated that the feature patterns of therapy had powerful ability to discriminate effective drug combinations from non-effective ones. By analyzing various features, it is shown that the enriched features occurred frequently in golden positive samples can help predict novel drug combinations. Copyright © 2017 Elsevier Ltd. All rights reserved.

A compact human-powered energy harvesting system

NASA Astrophysics Data System (ADS)

Rao, Yuan; McEachern, Kelly M.; Arnold, David P.

2013-12-01

This paper presents a fully functional, self-sufficient body-worn energy harvesting system for passively capturing energy from human motion, with the long-term vision of supplying power to portable, wearable, or even implanted electronic devices. The system requires no external power supplies and can bootstrap from zero-state-of-charge to generate electrical energy from walking, jogging and cycling; convert the induced ac voltage to a dc voltage; and then boost and regulate the dc voltage to charge a Li-ion-polymer battery. Tested under normal human activities (walking, jogging, cycling) when worn on different parts of the body, the 70 cm3 system is shown to charge a 3.7 V rechargeable battery at charge rates ranging from 33 μW to 234 μW.

Extreme Environment Capable, Modular and Scalable Power Processing Unit for Solar Electric Propulsion

NASA Technical Reports Server (NTRS)

Carr, Gregory A.; Iannello, Christopher J.; Chen, Yuan; Hunter, Don J.; DelCastillo, Linda; Bradley, Arthur T.; Stell, Christopher; Mojarradi, Mohammad M.

2013-01-01

This paper is to present a concept of a modular and scalable High Temperature Boost (HTB) Power Processing Unit (PPU) capable of operating at temperatures beyond the standard military temperature range. The various extreme environments technologies are also described as the fundamental technology path to this concept. The proposed HTB PPU is intended for power processing in the area of space solar electric propulsion, where reduction of in-space mass and volume are desired, and sometimes even critical, to achieve the goals of future space flight missions. The concept of the HTB PPU can also be applied to other extreme environment applications, such as geothermal and petroleum deep-well drilling, where higher temperature operation is required.

Extreme Environment Capable, Modular and Scalable Power Processing Unit for Solar Electric Propulsion

NASA Technical Reports Server (NTRS)

Carr, Gregory A.; Iannello, Christopher J.; Chen, Yuan; Hunter, Don J.; Del Castillo, Linda; Bradley, Arthur T.; Stell, Christopher; Mojarradi, Mohammad M.

2013-01-01

This paper is to present a concept of a modular and scalable High Temperature Boost (HTB) Power Processing Unit (PPU) capable of operating at temperatures beyond the standard military temperature range. The various extreme environments technologies are also described as the fundamental technology path to this concept. The proposed HTB PPU is intended for power processing in the area of space solar electric propulsion, where the reduction of in-space mass and volume are desired, and sometimes even critical, to achieve the goals of future space flight missions. The concept of the HTB PPU can also be applied to other extreme environment applications, such as geothermal and petroleum deep-well drilling, where higher temperature operation is required.

An inductor-based converter with EMI reduction for low-voltage thermoelectric energy harvesting

NASA Astrophysics Data System (ADS)

Wang, Chuang; Zhao, Kai; Li, Zunchao

2017-07-01

This paper presents a self-powered inductor-based converter which harvests thermoelectric energy and boosts extremely low voltage to a typical voltage level for supplying body sensor nodes. Electromagnetic interference (EMI) of the converter is reduced by spreading spectrum of fundamental frequency and harmonics via pseudo-random modulation, which is obtained via combining the linear feedback shift register and digitally controlled oscillator. Besides, the methods, namely extracting energy near MPP and reducing the power dissipation, are employed to improve the power efficiency. The presented inductor-based converter is designed and verified in CSMC CMOS 0.18-µm 1P6M process. The results reveal that it achieves the high efficiency and EMI reduction at the same time.

Compact self-powered synchronous energy extraction circuit design with enhanced performance

NASA Astrophysics Data System (ADS)

Liu, Weiqun; Zhao, Caiyou; Badel, Adrien; Formosa, Fabien; Zhu, Qiao; Hu, Guangdi

2018-04-01

Synchronous switching circuit is viewed as an effective solution of enhancing the generator’s performance and providing better adaptability for load variations. A critical issue for these synchronous switching circuits is the self-powered realization. In contrast with other methods, the electronic breaker possesses the advantage of simplicity and reliability. However, beside the energy consumption of the electronic breakers, the parasitic capacitance decreases the available piezoelectric voltage. In this technical note, a new compact design of the self-powered switching circuit using electronic breaker is proposed. The envelope diodes are excluded and only a single envelope capacitor is used. The parasitic capacitance is reduced to half with boosted performance while the components are reduced with cost saved.

Deciphering factors controlling groundwater arsenic spatial variability in Bangladesh

NASA Astrophysics Data System (ADS)

Tan, Z.; Yang, Q.; Zheng, C.; Zheng, Y.

2017-12-01

Elevated concentrations of geogenic arsenic in groundwater have been found in many countries to exceed 10 μg/L, the WHO's guideline value for drinking water. A common yet unexplained characteristic of groundwater arsenic spatial distribution is the extensive variability at various spatial scales. This study investigates factors influencing the spatial variability of groundwater arsenic in Bangladesh to improve the accuracy of models predicting arsenic exceedance rate spatially. A novel boosted regression tree method is used to establish a weak-learning ensemble model, which is compared to a linear model using a conventional stepwise logistic regression method. The boosted regression tree models offer the advantage of parametric interaction when big datasets are analyzed in comparison to the logistic regression. The point data set (n=3,538) of groundwater hydrochemistry with 19 parameters was obtained by the British Geological Survey in 2001. The spatial data sets of geological parameters (n=13) were from the Consortium for Spatial Information, Technical University of Denmark, University of East Anglia and the FAO, while the soil parameters (n=42) were from the Harmonized World Soil Database. The aforementioned parameters were regressed to categorical groundwater arsenic concentrations below or above three thresholds: 5 μg/L, 10 μg/L and 50 μg/L to identify respective controlling factors. Boosted regression tree method outperformed logistic regression methods in all three threshold levels in terms of accuracy, specificity and sensitivity, resulting in an improvement of spatial distribution map of probability of groundwater arsenic exceeding all three thresholds when compared to disjunctive-kriging interpolated spatial arsenic map using the same groundwater arsenic dataset. Boosted regression tree models also show that the most important controlling factors of groundwater arsenic distribution include groundwater iron content and well depth for all three thresholds. The probability of a well with iron content higher than 5mg/L to contain greater than 5 μg/L, 10 μg/L and 50 μg/L As is estimated to be more than 91%, 85% and 51%, respectively, while the probability of a well from depth more than 160m to contain more than 5 μg/L, 10 μg/L and 50 μg/L As is estimated to be less than 38%, 25% and 14%, respectively.

Comparison of control structures for a bidirectional high-frequency dc-dc converter

NASA Astrophysics Data System (ADS)

Himmelstoss, Felix A.; Kolar, Johann W.; Zach, Franz C.

1989-08-01

A system for dc-dc power conversion based on a buck-boost converter topology is presented. It makes power flow in both directions possible. The possibility of bidirectional power flow is useful for certain applications, such as uninterruptable power supplies. Starting from a structural diagram the transfer function of the system is derived. The controller for the converter is then designed. It is made up of a simple voltage controller, a voltage controller with an inner loop current controller (cascade control) and with two kinds of state space control. The transfer functions of the different system parts are derived and dimensioning guidelines for the controller sections are presented. The closed loop behavior of the bidirectional converter for the different control structures is analyzed based on simulation using duty cycle averaging. Bodediagrams and step responses are shown.

Boosting for detection of gene-environment interactions.

PubMed

Pashova, H; LeBlanc, M; Kooperberg, C

2013-01-30

In genetic association studies, it is typically thought that genetic variants and environmental variables jointly will explain more of the inheritance of a phenotype than either of these two components separately. Traditional methods to identify gene-environment interactions typically consider only one measured environmental variable at a time. However, in practice, multiple environmental factors may each be imprecise surrogates for the underlying physiological process that actually interacts with the genetic factors. In this paper, we develop a variant of L(2) boosting that is specifically designed to identify combinations of environmental variables that jointly modify the effect of a gene on a phenotype. Because the effect modifiers might have a small signal compared with the main effects, working in a space that is orthogonal to the main predictors allows us to focus on the interaction space. In a simulation study that investigates some plausible underlying model assumptions, our method outperforms the least absolute shrinkage and selection and Akaike Information Criterion and Bayesian Information Criterion model selection procedures as having the lowest test error. In an example for the Women's Health Initiative-Population Architecture using Genomics and Epidemiology study, the dedicated boosting method was able to pick out two single-nucleotide polymorphisms for which effect modification appears present. The performance was evaluated on an independent test set, and the results are promising. Copyright © 2012 John Wiley & Sons, Ltd.

Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen.

PubMed

Bauer, Asli; Podola, Lilli; Mann, Philipp; Missanga, Marco; Haule, Antelmo; Sudi, Lwitiho; Nilsson, Charlotta; Kaluwa, Bahati; Lueer, Cornelia; Mwakatima, Maria; Munseri, Patricia J; Maboko, Leonard; Robb, Merlin L; Tovanabutra, Sodsai; Kijak, Gustavo; Marovich, Mary; McCormack, Sheena; Joseph, Sarah; Lyamuya, Eligius; Wahren, Britta; Sandström, Eric; Biberfeld, Gunnel; Hoelscher, Michael; Bakari, Muhammad; Kroidl, Arne; Geldmacher, Christof

2017-09-15

Prime-boost vaccination strategies against HIV-1 often include multiple variants for a given immunogen for better coverage of the extensive viral diversity. To study the immunologic effects of this approach, we characterized breadth, phenotype, function, and specificity of Gag-specific T cells induced by a DNA-prime modified vaccinia virus Ankara (MVA)-boost vaccination strategy, which uses mismatched Gag immunogens in the TamoVac 01 phase IIa trial. Healthy Tanzanian volunteers received three injections of the DNA-SMI vaccine encoding a subtype B and AB-recombinant Gag p37 and two vaccinations with MVA-CMDR encoding subtype A Gag p55 Gag-specific T-cell responses were studied in 42 vaccinees using fresh peripheral blood mononuclear cells. After the first MVA-CMDR boost, vaccine-induced gamma interferon-positive (IFN-γ + ) Gag-specific T-cell responses were dominated by CD4 + T cells ( P < 0.001 compared to CD8 + T cells) that coexpressed interleukin-2 (IL-2) (66.4%) and/or tumor necrosis factor alpha (TNF-α) (63.7%). A median of 3 antigenic regions were targeted with a higher-magnitude median response to Gag p24 regions, more conserved between prime and boost, compared to those of regions within Gag p15 (not primed) and Gag p17 (less conserved; P < 0.0001 for both). Four regions within Gag p24 each were targeted by 45% to 74% of vaccinees upon restimulation with DNA-SMI-Gag matched peptides. The response rate to individual antigenic regions correlated with the sequence homology between the MVA- and DNA Gag-encoded immunogens ( P = 0.04, r 2 = 0.47). In summary, after the first MVA-CMDR boost, the sequence-mismatched DNA-prime MVA-boost vaccine strategy induced a Gag-specific T-cell response that was dominated by polyfunctional CD4 + T cells and that targeted multiple antigenic regions within the conserved Gag p24 protein. IMPORTANCE Genetic diversity is a major challenge for the design of vaccines against variable viruses. While including multiple variants for a given immunogen in prime-boost vaccination strategies is one approach that aims to improve coverage for global virus variants, the immunologic consequences of this strategy have been poorly defined so far. It is unclear whether inclusion of multiple variants in prime-boost vaccination strategies improves recognition of variant viruses by T cells and by which mechanisms this would be achieved, either by improved cross-recognition of multiple variants for a given antigenic region or through preferential targeting of antigenic regions more conserved between prime and boost. Engineering vaccines to induce adaptive immune responses that preferentially target conserved antigenic regions of viral vulnerability might facilitate better immune control after preventive and therapeutic vaccination for HIV and for other variable viruses. Copyright © 2017 American Society for Microbiology.

Application of Distributed DC/DC Electronics in Photovoltaic Systems

NASA Astrophysics Data System (ADS)

Kabala, Michael

In a typical residential, commercial or utility grade photovoltaic (PV) system, PV modules are connected in series and in parallel to form an array that is connected to a standard DC/AC inverter, which is then connected directly to the grid. This type of standard installation; however, does very little to maximize the energy output of the solar array if certain conditions exist. These conditions could include age, temperature, irradiance and other factors that can cause mismatch between PV modules in an array that severely cripple the output power of the system. Since PV modules are typically connected in series to form a string, the output of the entire string is limited by the efficiency of the weakest module. With PV module efficiencies already relatively low, it is critical to extract the maximum power out of each module in order to make solar energy an economically viable competitor to oil and gas. Module level DC/DC electronics with maximum power point (MPP) tracking solves this issue by decoupling each module from the string in order for the module to operate independently of the geometry and complexity of the surrounding system. This allows each PV module to work at its maximum power point by transferring the maximum power the module is able to deliver directly to the load by either boosting (stepping up) the voltage or bucking (stepping down) the voltage. The goal of this thesis is to discuss the development of a per-module DC/DC converter in order to maximize the energy output of a PV module and reduce the overall cost of the system by increasing the energy harvest.

The case-only test for gene-environment interaction is not uniformly powerful: an empirical example

PubMed Central

Wu, Chen; Chang, Jiang; Ma, Baoshan; Miao, Xiaoping; Zhou, Yifeng; Liu, Yu; Li, Yun; Wu, Tangchun; Hu, Zhibin; Shen, Hongbing; Jia, Weihua; Zeng, Yixin; Lin, Dongxin; Kraft, Peter

2016-01-01

The case-only test has been proposed as a more powerful approach to detect gene-environment (G×E) interactions. This approach assumes that the genetic and environmental factors are independent. While it is well known that Type I error rate will increase if this assumption is violated, it is less widely appreciated that gene-environment correlation can also lead to power loss. We illustrate this phenomenon by comparing the performance of the case-only test to other approaches to detect G×E interactions in a genome-wide association study of esophageal squamous carcinoma (ESCC) in Chinese populations. Some of these approaches do not use information on the correlation between exposure and genotype (standard logistic regression), while others seek to use this information in a robust fashion to boost power without increasing Type I error (two-step, empirical Bayes and cocktail methods). G×E interactions were identified involving drinking status and two regions containing genes in the alcohol metabolism pathway, 4q23 and 12q24. Although the case-only test yielded the most significant tests of G×E interaction in the 4q23 region, the case-only test failed to identify significant interactions in the 12q24 region which were readily identified using other approaches. The low power of the case-only test in the 12q24 region is likely due to the strong inverse association between the SNPs in this region and drinking status. This example underscores the need to consider multiple approaches to detect gene-environment interactions, as different tests are more or less sensitive to different alternative hypotheses and violations of the gene-environment independence assumption. PMID:23595356

Financing maneuvers. Two opportunities to boost a hospital's working capital.

PubMed

Ferconio, S; Lane, M R

1991-10-01

Two receivables financing approaches, factoring and asset-backed securitization, offer an initial cash flow boost and a predictable source for continual cash flow. In a typical receivables factoring program, a healthcare organization receives advance funding from its receivables and reduces collection and follow-up efforts required of its staff. In exchange, the organization: Sells receivables at a discount between 5 percent and 10 percent off face value; and Pays a factoring fee of up to 20 percent of sold receivables. In a typical asset-backed securitization: Proceeds generated from the sale of A1-rated commercial paper are used to purchase receivables from a hospital; Accounts receivable eligible for sale are advance-funded at a level between 80 and 90 percent, with the unfunded portion remaining an asset of the hospital; The hospital is responsible for collection and follow-up activities; and An asset manager maintains cash collections to retire commercial paper notes and pay administrative costs. A healthcare organization interested in receivables financing should review each option's structure and benefits to assess advance funding provided, costs, a seller's level of control, and program eligibility requirements.

Explaining Meiji Japans Top Down Revolution

DTIC Science & Technology

2017-12-01

enabled Japan to become a great power also provides insights into how Japan became what it is today—an economically strong but militarily weak country...top- down nature of the Japanese revolution allowed for effective decision-making that centralized domestic politics and boosted economic ...other road focuses on changes made to compete with the West in the economic and military realm. Since Meiji Japan began in reaction to hostile Western

Echoing down from Wall St. Proposed new accounting standards could bring new guidelines for not-for-profits; conflicts between boards, CFOs could result. Merck, Allegheny, HBO & Co.

PubMed

Jaklevic, Mary Chris; Becker, Cinda; Morrissey, John

2002-07-15

The cause of good governance in healthcare got a boost when President Bush lectured power brokers on Wall Street last week, saying he would aggressively pursue unscrupulous executives. The healthcare industry, which has been trying to scrub clean its own image, is no stranger to the kind of scandals plaguing other industries.

Industry - Military Energy Symposium, held 21-23 October 1980, San Antonio, Texas

DTIC Science & Technology

1980-10-21

unless the best available technology is applied to many sources including those the size of airports . Further discussion of these issues will hopefully...particularly with naphthenic fuels. A similar weakness applies to correlations of net heat of combustion. Some additional correlating parameters...Viscosity Boost pump power Line size and weight Thermal Stability Gum, deposits, nozzle coking Specific Heat Avionics and engine oil cooling Aromatics

Rn gravity is kicking and alive: The cases of Orion and NGC 3198

NASA Astrophysics Data System (ADS)

Salucci, Paolo; Frigerio Martins, Christiane; Karukes, Ekaterina

2014-08-01

We analyzed the Rotation Curves (RCs) of two crucial objects, the dwarf galaxy Orion and the low luminosity Spiral NGC 3198, in the framework of Rn gravity. We surprisingly found that the no dark matter (DM) power-law F(R) case fits them well, performing much better than LCDM halo models. The level of this unexpected success can be a boost for Rn gravity.

Development of a cryogenic DC-low noise amplifier for SQuID-based readout electronics

NASA Astrophysics Data System (ADS)

Macculi, C.; Torrioli, G.; Di Giorgio, A.; Spinoglio, L.; Piro, Luigi

2014-07-01

We present the preliminary results of the design and test activities for a DC cryogenic low noise amplifier for the SAFARI imaging spectrometer, planned to be onboard the SPICA mission, necessary not only to drive, as usual, the voltage signal produced by the SQuID but also to boost such signals over about 7 meter of path towards the warm feedback electronics. This development has been done in the framework of the mission preparation studies, within the European Consortium for the development of the SAFARI instrument. The actual configuration of the SAFARI focal plane assembly (FPA), indeed, foresees a long distance to the warm back end electronics. It is therefore mandatory to boost the faint electric signal coming from the SQuID device by keeping under control both power dissipation and noise: this is the main role of the designed Cryogenic Low Noise Amplifier (LNA). Working at 136K, it has a differential input gain-stage, and a differential balanced voltage buffer output stage, running at few mW target overall power. At present the design is based on the use of Heterojunction Si:Ge transistors, the required bandwidth is DC-4MHz and the required noise lower than 1 nV/rtHz.

A Simple but Powerful Heuristic Method for Accelerating k-Means Clustering of Large-Scale Data in Life Science.

PubMed

Ichikawa, Kazuki; Morishita, Shinichi

2014-01-01

K-means clustering has been widely used to gain insight into biological systems from large-scale life science data. To quantify the similarities among biological data sets, Pearson correlation distance and standardized Euclidean distance are used most frequently; however, optimization methods have been largely unexplored. These two distance measurements are equivalent in the sense that they yield the same k-means clustering result for identical sets of k initial centroids. Thus, an efficient algorithm used for one is applicable to the other. Several optimization methods are available for the Euclidean distance and can be used for processing the standardized Euclidean distance; however, they are not customized for this context. We instead approached the problem by studying the properties of the Pearson correlation distance, and we invented a simple but powerful heuristic method for markedly pruning unnecessary computation while retaining the final solution. Tests using real biological data sets with 50-60K vectors of dimensions 10-2001 (~400 MB in size) demonstrated marked reduction in computation time for k = 10-500 in comparison with other state-of-the-art pruning methods such as Elkan's and Hamerly's algorithms. The BoostKCP software is available at http://mlab.cb.k.u-tokyo.ac.jp/~ichikawa/boostKCP/.

Stacking open-capillary electroosmotic pumps in series to boost the pumping pressure to drive high-performance liquid chromatographic separations.

PubMed

He, Chiyang; Zhu, Zaifang; Gu, Congying; Lu, Joann; Liu, Shaorong

2012-03-02

Numerous micropumps have been developed, but few of them can produce adequate flow rate and pressure for high-performance liquid chromatography (HPLC) applications. We have recently developed an innovative hybrid electroosmotic pump (EOP) to solve this problem. The basic unit of a hybrid pump consists of a +EOP (the pumping element is positively charged) and a -EOP (the pumping element is negatively charged). The outlet of the +EOP is then joined with the inlet of the -EOP, forming a basic pump unit, while the anode of a positive high voltage (HV) power supply is placed at the joint. The inlet and outlet of this pump unit are electrically grounded. With this configuration, we can stack many of such pump units in series to boost the pumping power. In this work, we describe in details how an open-capillary hybrid EOP is constructed and characterize this pump systematically. We also show that a hybrid EOP with ten serially stacked pump units can deliver a maximum pressure of 21.5 MPa (∼3100 psi). We further demonstrate the feasibility of using this hybrid EOP to drive eluents for HPLC separations of proteins and peptides. Copyright © 2012 Elsevier B.V. All rights reserved.

Stacking open-capillary electroosmotic pumps in series to boost the pumping pressure to drive high-performance liquid chromatographic separations

DOE PAGES

He, Chiyang; Zhu, Zaifang; Gu, Congying; ...

2012-01-09

Numerous micropumps have been developed, but few of them can produce adequate flow rate and pressure for high-performance liquid chromatography (HPLC) applications. We have recently developed an innovative hybrid electroosmotic pump (EOP) to solve this problem. The basic unit of a hybrid pump consists of a +EOP (the pumping element is positively charged) and a -EOP (the pumping element is negatively charged). The outlet of the +EOP is then joined with the inlet of the -EOP, forming a basic pump unit, while the anode of a positive high voltage (HV) power supply is placed at the joint. The inlet andmore » outlet of this pump unit are electrically grounded. With this configuration, we can stack many of such pump units in series to boost the pumping power. In this work, we describe in details how an open-capillary hybrid EOP is constructed and characterize this pump systematically. We also show that a hybrid EOP with ten serially stacked pump units can deliver a maximum pressure of 21.5 MPa (~3100 psi). Here, we further demonstrate the feasibility of using this hybrid EOP to drive eluents for HPLC separations of proteins and peptides.« less

Design, fabrication, and experimental characterization of plasmonic photoconductive terahertz emitters.

PubMed

Berry, Christopher; Hashemi, Mohammad Reza; Unlu, Mehmet; Jarrahi, Mona

2013-07-08

In this video article we present a detailed demonstration of a highly efficient method for generating terahertz waves. Our technique is based on photoconduction, which has been one of the most commonly used techniques for terahertz generation (1-8). Terahertz generation in a photoconductive emitter is achieved by pumping an ultrafast photoconductor with a pulsed or heterodyned laser illumination. The induced photocurrent, which follows the envelope of the pump laser, is routed to a terahertz radiating antenna connected to the photoconductor contact electrodes to generate terahertz radiation. Although the quantum efficiency of a photoconductive emitter can theoretically reach 100%, the relatively long transport path lengths of photo-generated carriers to the contact electrodes of conventional photoconductors have severely limited their quantum efficiency. Additionally, the carrier screening effect and thermal breakdown strictly limit the maximum output power of conventional photoconductive terahertz sources. To address the quantum efficiency limitations of conventional photoconductive terahertz emitters, we have developed a new photoconductive emitter concept which incorporates a plasmonic contact electrode configuration to offer high quantum-efficiency and ultrafast operation simultaneously. By using nano-scale plasmonic contact electrodes, we significantly reduce the average photo-generated carrier transport path to photoconductor contact electrodes compared to conventional photoconductors (9). Our method also allows increasing photoconductor active area without a considerable increase in the capacitive loading to the antenna, boosting the maximum terahertz radiation power by preventing the carrier screening effect and thermal breakdown at high optical pump powers. By incorporating plasmonic contact electrodes, we demonstrate enhancing the optical-to-terahertz power conversion efficiency of a conventional photoconductive terahertz emitter by a factor of 50 (10).

Future of anti-PD-1/PD-L1 applications: Combinations with other therapeutic regimens.

PubMed

Song, Mengjia; Chen, Xinfeng; Wang, Liping; Zhang, Yi

2018-04-01

Programmed cell death 1 (PD-1)/programmed cell death 1 ligand (PD-L1) blockade has shown promising effects in cancer immunotherapy. Removing the so-called " brakes" on T cell immune responses by blocking the PD-1/PD-L1 check point should boost anti-tumor immunity and provide durable tumor regression for cancer patients. However, 30%-60% of patients show no response to PD-1/PD-L1 blockade. Thus, it is urgent to explore the underlying resistance mechanisms to improve sensitivity to anti-PD-1/PD-L1 therapy. We propose that the mechanisms promoting resistance mainly include T cell exclusion or exhaustion at the tumor site, immunosuppressive factors in the tumor microenvironment (TME), and a range of tumor-intrinsic factors. This review highlights the power of studying the cellular and molecular mechanisms of resistance to improve the rational design of combination therapeutic strategies that can be translated to the clinic. Here, we briefly discuss the development of PD-1/PD-L1 blockade agents and focus on the current issues and future prospects for potential combinatorial therapeutic strategies that include anti-PD-1/PD-L1 therapy, based upon the available preclinical and clinical data.

Characterization of poly methyl methaacrylate and reduced graphene oxide composite for application as electrolyte in dye sensitized solar cells

NASA Astrophysics Data System (ADS)

Shrivatsav, Roshan; Mahalingam, Vignesh; Lakshmi Narayanan, E. R.; Naveen Balaji, N.; Balu, Murali; Krishna Prasad, R.; Kumaresan, Duraisamy

2018-04-01

Quasi-solid state iodide/triiodide redox electrolyte containing reduced graphene oxide and poly (methyl methaacrylate) (RGO-PMMA) composites for the fabrication of more durable, high performance dye sensitized solar cells are prepared. The morphological analysis of prepared RGO-PMMA composites showed formation of spherical like morphologies of RGO dispersed PMMA particles with their macroscopic inter-particle networks having voids. The x ray diffraction and electrical conductivity studies showed the addition of 1 wt% of filler RGO into amorphous PMMA matrix increased the electrical conductivity of the polymer composite about three orders of magnitude from 10‑7 and 10‑4 S cm‑1. Further, the photovoltaic current-voltage analysis of DSSCs with different RGO-PMMA composite based iodide/triiodide redox electrolytes showed the highest power conversion efficiency of 5.38% and the fill factor 0.63 for 2% RGO-PMMA electrolyte. The EIS analysis showed an increased recombination resistance (Rct2) at TiO2 electrode/dye/electrolyte interface due to the better electrical conductivity of RGO with good ionic conductivity in 2% RGO-PMMA composite based redox electrolyte boosted the generation of a high current density and fill factor in their DSSCs.

Isolated and soft-switched power converter

DOEpatents

Peng, Fang Zheng; Adams, Donald Joe

2002-01-01

An isolated and soft-switched power converter is used for DC/DC and DC/DC/AC power conversion. The power converter includes two resonant tank circuits coupled back-to-back through an isolation transformer. Each resonant tank circuit includes a pair of resonant capacitors connected in series as a resonant leg, a pair of tank capacitors connected in series as a tank leg, and a pair of switching devices with anti-parallel clamping diodes coupled in series as resonant switches and clamping devices for the resonant leg. The power converter is well suited for DC/DC and DC/DC/AC power conversion applications in which high-voltage isolation, DC to DC voltage boost, bidirectional power flow, and a minimal number of conventional switching components are important design objectives. For example, the power converter is especially well suited to electric vehicle applications and load-side electric generation and storage systems, and other applications in which these objectives are important. The power converter may be used for many different applications, including electric vehicles, hybrid combustion/electric vehicles, fuel-cell powered vehicles with low-voltage starting, remote power sources utilizing low-voltage DC power sources, such as photovoltaics and others, electric power backup systems, and load-side electric storage and generation systems.

Effective Induction of Simian Immunodeficiency Virus-Specific Cytotoxic T Lymphocytes in Macaques by Using a Multiepitope Gene and DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccination Regimen

PubMed Central

Hanke, Tomas; Samuel, Rachel V.; Blanchard, Tom J.; Neumann, Veronica C.; Allen, Todd M.; Boyson, Jon E.; Sharpe, Sally A.; Cook, Nicola; Smith, Geoffrey L.; Watkins, David I.; Cranage, Martin P.; McMichael, Andrew J.

1999-01-01

DNA and modified vaccinia virus Ankara (MVA) are vaccine vehicles suitable and safe for use in humans. Here, by using a multicytotoxic T-lymphocyte (CTL) epitope gene and a DNA prime-MVA boost vaccination regimen, high levels of CTLs specific for a single simian immunodeficiency virus (SIV) gag-derived epitope were elicited in rhesus macaques. These vaccine-induced CTLs were capable of killing SIV-infected cells in vitro. Fluorescence-activated cell sorter analysis using soluble tetrameric major histocompatibility complex-peptide complexes showed that the vaccinated animals had 1 to 5% circulating CD8+ lymphocytes specific for the vaccine epitope, frequencies comparable to those in SIV-infected monkeys. Upon intrarectal challenge with pathogenic SIVmac251, no evidence for protection was observed in at least two of the three vaccinated animals. This study does not attempt to define correlates of protective immunity nor design a protective vaccine against immunodeficiency viruses, but it demonstrates clearly that the DNA prime-MVA boost regimen is an effective protocol for induction of CTLs in macaques. It also shows that powerful tools for studying the role of CTLs in the control of SIV and human immunodeficiency virus infections are now available: epitope-based vaccines, a protocol for an effective induction of CTLs in primates, and a simple and sensitive method for quantitation of epitope-specific T cells. The advantages of the DNA prime-MVA boost regimen as well as the correlations of tetramer staining of peripheral blood lymphocytes with CTL killing in vitro and postchallenge control of viremia are discussed. PMID:10438842

Detecting opinion spams through supervised boosting approach.

PubMed

Hazim, Mohamad; Anuar, Nor Badrul; Ab Razak, Mohd Faizal; Abdullah, Nor Aniza

2018-01-01

Product reviews are the individual's opinions, judgement or belief about a certain product or service provided by certain companies. Such reviews serve as guides for these companies to plan and monitor their business ventures in terms of increasing productivity or enhancing their product/service qualities. Product reviews can also increase business profits by convincing future customers about the products which they have interest in. In the mobile application marketplace such as Google Playstore, reviews and star ratings are used as indicators of the application quality. However, among all these reviews, hereby also known as opinions, spams also exist, to disrupt the online business balance. Previous studies used the time series and neural network approach (which require a lot of computational power) to detect these opinion spams. However, the detection performance can be restricted in terms of accuracy because the approach focusses on basic, discrete and document level features only thereby, projecting little statistical relationships. Aiming to improve the detection of opinion spams in mobile application marketplace, this study proposes using statistical based features that are modelled through the supervised boosting approach such as the Extreme Gradient Boost (XGBoost) and the Generalized Boosted Regression Model (GBM) to evaluate two multilingual datasets (i.e. English and Malay language). From the evaluation done, it was found that the XGBoost is most suitable for detecting opinion spams in the English dataset while the GBM Gaussian is most suitable for the Malay dataset. The comparative analysis also indicates that the implementation of the proposed statistical based features had achieved a detection accuracy rate of 87.43 per cent on the English dataset and 86.13 per cent on the Malay dataset.

Using semantic memory to boost 'episodic' recall in a case of developmental amnesia.

PubMed

Brandt, Karen R; Gardiner, John M; Vargha-Khadem, Faraneh; Baddeley, Alan D; Mishkin, Mortimer

2006-07-17

We report two experiments that investigated factors that might boost 'episodic' recall for Jon, a developmental amnesic whose episodic memory is gravely impaired but whose semantic memory seems relatively normal. Experiment 1 showed that Jon's recall improved following a semantic study task compared with a non-semantic study task, as well as following four repeated study trials compared with only one. Experiment 2 additionally revealed that Jon's recall improved after acting compared with reading action phrases at study, but only if the phrases were well integrated semantically. The results provide some support for the hypothesis that Jon's 'episodic' recall depends on the extent to which he is able to retrieve events using semantic memory.

High frequency capacitor-diode voltage multiplier dc-dc converter development

NASA Technical Reports Server (NTRS)

Kisch, J. J.; Martinelli, R. M.

1977-01-01

A power conditioner was developed which used a capacitor diode voltage multiplier to provide a high voltage without the use of a step-up transformer. The power conditioner delivered 1200 Vdc at 100 watts and was operated from a 120 Vdc line. The efficiency was in excess of 90 percent. The component weight was 197 grams. A modified boost-add circuit was used for the regulation. A short circuit protection circuit was used which turns off the drive circuit upon a fault condition, and recovers within 5 ms after removal of the short. High energy density polysulfone capacitors and high speed diodes were used in the multiplier circuit.

Grumman and SDI-related technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, B.

1985-01-01

The application of Grumman Corporation's aerospace and nuclear fusion technology to the Strategic Defense Initiative (SDI) program has taken place in at least five major areas. These include infrared boost surveillance and tracking to detect intercontinental ballistic missiles just after launch, space-based radar, neutral particle beam platforms, nuclear electric power and propulsion units in space, and battle management systems. The author summarizes developments in each of these areas to illustrate how Grumman has responded to the request that the scientific and industrial communities pursue innovative, high-risk concepts involving materials, structures, space power, space physics, and kinetic energy weapon concepts. 3more » figures.« less

Research on the supercapacitor support schemes for LVRT of variable-frequency drive in the thermal power plant

NASA Astrophysics Data System (ADS)

Han, Qiguo; Zhu, Kai; Shi, Wenming; Wu, Kuayu; Chen, Kai

2018-02-01

In order to solve the problem of low voltage ride through(LVRT) of the major auxiliary equipment’s variable-frequency drive (VFD) in thermal power plant, the scheme of supercapacitor paralleled in the DC link of VFD is put forward, furthermore, two solutions of direct parallel support and voltage boost parallel support of supercapacitor are proposed. The capacitor values for the relevant motor loads are calculated according to the law of energy conservation, and they are verified by Matlab simulation. At last, a set of test prototype is set up, and the test results prove the feasibility of the proposed schemes.

Using Chou's pseudo amino acid composition based on approximate entropy and an ensemble of AdaBoost classifiers to predict protein subnuclear location.

PubMed

Jiang, Xiaoying; Wei, Rong; Zhao, Yanjun; Zhang, Tongliang

2008-05-01

The knowledge of subnuclear localization in eukaryotic cells is essential for understanding the life function of nucleus. Developing prediction methods and tools for proteins subnuclear localization become important research fields in protein science for special characteristics in cell nuclear. In this study, a novel approach has been proposed to predict protein subnuclear localization. Sample of protein is represented by Pseudo Amino Acid (PseAA) composition based on approximate entropy (ApEn) concept, which reflects the complexity of time series. A novel ensemble classifier is designed incorporating three AdaBoost classifiers. The base classifier algorithms in three AdaBoost are decision stumps, fuzzy K nearest neighbors classifier, and radial basis-support vector machines, respectively. Different PseAA compositions are used as input data of different AdaBoost classifier in ensemble. Genetic algorithm is used to optimize the dimension and weight factor of PseAA composition. Two datasets often used in published works are used to validate the performance of the proposed approach. The obtained results of Jackknife cross-validation test are higher and more balance than them of other methods on same datasets. The promising results indicate that the proposed approach is effective and practical. It might become a useful tool in protein subnuclear localization. The software in Matlab and supplementary materials are available freely by contacting the corresponding author.

A cosmetic evaluation of breast cancer treatment: A randomized study of radiotherapy boost technique

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vass, Sylvie; Bairati, Isabelle

2005-08-01

Purpose: To compare cosmetic results of two different radiotherapy (RT) boost techniques used in the treatment of breast cancer after whole breast radiotherapy and to identify factors affecting cosmetic outcomes. Methods and Materials: Between 1996 and 1998, 142 patients with Stage I and II breast cancer were treated with breast conservative surgery and adjuvant RT. Patients were then randomly assigned to receive a boost dose of 15 Gy delivered to the tumor bed either by iridium 192, or a combination of photons and electrons. Cosmetic evaluations were done on a 6-month basis, with a final evaluation at 36 months aftermore » RT. The evaluations were done using a panel of global and specific subjective scores, a digitized scoring system using the breast retraction assessment (BRA) measurement, and a patient's self-assessment evaluation. As cosmetic results were graded according to severity, the comparison of boost techniques was done using the ordinal logistic regression model. Adjusted odds ratios (OR) and their 95% confidence intervals (CI) are presented. Results: At 36 months of follow-up, there was no significant difference between the two groups with respect to the global subjective cosmetic outcome (OR = 1.40; 95%CI = 0.69-2.85, p = 0.35). Good to excellent scores were observed in 65% of implant patients and 62% of photon/electron patients. At 24 months and beyond, telangiectasia was more severe in the implant group with an OR of 9.64 (95%CI = 4.05-22.92, p < 0.0001) at 36 months. The only variable associated with a worse global cosmetic outcome was the presence of concomitant chemotherapy (OR = 3.87; 95%CI = 1.74-8.62). The BRA value once adjusted for age, concomitant chemotherapy, and boost volume showed a positive association with the boost technique. The BRA value was significantly greater in the implant group (p 0.03). There was no difference in the patient's final self-assessment score between the two groups. Three variables were statistically associated with an adverse self-evaluation: an inferior quadrant tumor localization, postoperative hematoma, and concomitant chemotherapy. Conclusions: Although this trial showed that at 36 months of follow-up, there were no significant differences in the overall global cosmetic scores between the implant boost group and the photon/electron boost group, telangiectasia was more severe and the BRA value was greater in the implant group.« less

Separation of heat and charge currents for boosted thermoelectric conversion

NASA Astrophysics Data System (ADS)

Mazza, Francesco; Valentini, Stefano; Bosisio, Riccardo; Benenti, Giuliano; Giovannetti, Vittorio; Fazio, Rosario; Taddei, Fabio

2015-06-01

In a multiterminal device the (electronic) heat and charge currents can follow different paths. In this paper we introduce and analyze a class of multiterminal devices where this property is pushed to its extreme limits, with charge and heat currents flowing in different reservoirs. After introducing the main characteristics of this heat-charge current separation regime, we show how to realize it in a multiterminal device with normal and superconducting leads. We demonstrate that this regime allows us to control independently heat and charge flows and to greatly enhance thermoelectric performances at low temperatures. We analyze in detail a three-terminal setup involving a superconducting lead, a normal lead, and a voltage probe. For a generic scattering region we show that in the regime of heat-charge current separation both the power factor and the figure of merit Z T are highly increased with respect to a standard two-terminal system. These results are confirmed for the specific case of a system consisting of three coupled quantum dots.

Mach-Effect thruster model

NASA Astrophysics Data System (ADS)

Tajmar, M.

2017-12-01

The Mach-Effect thruster is a propellantless propulsion concept that has been in development by J.F. Woodward for more than two decades. It consists of a piezo stack that produces mass fluctuations, which in turn can lead to net time-averaged thrusts. So far, thrust predictions had to use an efficiency factor to explain some two orders of magnitude discrepancy between model and observations. Here, a detailed 1D analytical model is presented that takes piezo material parameters and geometry dimensions into account leading to correct thrust predictions in line with experimental measurements. Scaling laws can now be derived to improve thrust range and efficiency. An important difference in this study is that only the mechanical power developed by the piezo stack is considered to be responsible for the mass fluctuations, whereas prior works focused on the electrical energy into the system. This may explain why some previous designs did not work as expected. The good match between this new mathematical formulation and experiments should boost confidence in the Mach effect thruster concept to stimulate further developments.

Stable electrolyte for high voltage electrochemical double-layer capacitors

DOE PAGES

Ruther, Rose E.; Sun, Che -Nan; Holliday, Adam; ...

2016-12-28

A simple electrolyte consisting of NaPF 6 salt in 1,2-dimethoxyethane (DME) can extend the voltage window of electric double-layer capacitors (EDLCs) to >3.5 V. DME does not passivate carbon electrodes at very negative potentials (near Na/Na +), extending the practical voltage window by about 1.0 V compared to standard, non-aqueous electrolytes based on acetonitrile. The voltage window is demonstrated in two- and three-electrode cells using a combination of electrochemical impedance spectroscopy (EIS), charge-discharge cycling, and measurements of leakage current. DME-based electrolytes cannot match the high conductivity of acetonitrile solutions, but they can satisfy applications that demand high energy density atmore » moderate power. The conductivity of NaPF 6 in DME is comparable to commercial lithium-ion battery electrolytes and superior to most ionic liquids. Lastly, factors that limit the voltage window and EDLC energy density are discussed, and strategies to further boost energy density are proposed.« less

Contrastive thermoelectric properties of strained SnSe crystals from the first-principles calculations

NASA Astrophysics Data System (ADS)

Tang, Yu; Cheng, Feng; Li, Decong; Deng, Shuping; Chen, Zhong; Sun, Luqi; Liu, Wenting; Shen, Lanxian; Deng, Shukang

2018-06-01

SnSe is a promising thermoelectric material with a record high dimensionless figure of merit ZT at high temperature ∼923 K. However, the ZT values for low-Temperature Pnma phase SnSe are just 0.1-0.9. Here, we use First-principle combine with Boltzmann transport theory methods to study the effect of tensile and compressible strain on the thermoelectric transport properties. The power factor of SnSe with -4% strain have a large boost along b and c directions of 7.7 and 3.9 μW cm-1 K-2, respectively, which are 2.5 and 2 times as large as those pristine SnSe. The charge density distributions reveal that the overlap of wave function has significant change due to the changed bond lengths and bond angles under different strain, which lead to the change of band gap and band dispersion. Our work provides a new effective strategy to enhance the thermoelectric properties of materials.

Critical Essay: Building new management theories on sound data? The case of neuroscience

PubMed Central

Lindebaum, Dirk

2015-01-01

In this critical essay, I contend that accelerating demands for novel theories in management studies imply that new methodologies and data are sometimes accepted prematurely as supply of these novel theories. This point is illustrated with reference to how neuroscience can inform management research. I propose two demand forces that foster the increased focus on neuroscience in management studies, these being (i) the direction of public research funding, and (ii) publication bias as a boost for journal impact factor. Looking at the supply side, I note that (i) the statistical power of studies using functional magnetic resonance imaging (or fMRI, the ‘gold’ standard) is unacceptably low, (ii) the use of imprecise ‘motherhood’ statements, and (iii) the dismissal of ethical concerns in the formulation of management theories and practice informed by neuroscience. I then briefly outline the bad consequences of this for management theory and practice, emphasize why it is important to prevent these consequences, and offer some methodological suggestions for future research. PMID:27041766

Novel concepts for the compression of large volumes of carbon dioxide-phase III

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moore, J. Jeffrey; Allison, Timothy C.; Evans, Neal D.

In the effort to reduce the release of CO 2 greenhouse gases to the atmosphere, sequestration of CO 2 from Integrated Gasification Combined Cycle (IGCC) and Oxy-Fuel power plants is being pursued. This approach, however, requires significant compression power to boost the pressure to typical pipeline levels. The penalty can be as high as 8-12% on a typical IGCC plant. The goal of this research is to reduce this penalty through novel compression concepts and integration with existing IGCC processes. The primary objective of the study of novel CO 2 compression concepts is to reliably boost the pressure of COmore » 2 to pipeline pressures with the minimal amount of energy required. Fundamental thermodynamics were studied to explore pressure rise in both liquid and gaseous states. For gaseous compression, the project investigated novel methods to compress CO 2 while removing the heat of compression internal to the compressor. The highpressure ratio, due to the delivery pressure of the CO 2 for enhanced oil recovery, results in significant heat of compression. Since less energy is required to boost the pressure of a cooler gas stream, both upstream and inter-stage cooling is desirable. While isothermal compression has been utilized in some services, it has not been optimized for the IGCC environment. Phase I of this project determined the optimum compressor configuration and developed technology concepts for internal heat removal. Other compression options using liquefied CO 2 and cryogenic pumping were explored as well. Preliminary analysis indicated up to a 35% reduction in power is possible with the new concepts being considered. In the Phase II program, two experimental test rigs were developed to investigate the two concepts further. A new pump loop facility was constructed to qualify a cryogenic turbopump for use on liquid CO 2 . Also, an internally cooled compressor diaphragm was developed and tested in a closed loop compressor facility using CO 2 . Both test programs successfully demonstrated good performance and mechanical behavior. In Phase III, a pilot compression plant consisting of a multi-stage centrifugal compressor with cooled diaphragm technology has been designed, constructed, and tested. Comparative testing of adiabatic and cooled tests at equivalent inlet conditions shows that the cooled diaphragms reduce power consumption by 3-8% when the compressor is operated as a back-to-back unit and by up to 9% when operated as a straight-though compressor with no intercooler. The power savings, heat exchanger effectiveness, and temperature drops for the cooled diaphragm were all slightly higher than predicted values but showed the same trends.« less

Thomas precession, Wigner rotations and gauge transformations

NASA Technical Reports Server (NTRS)

Han, D.; Kim, Y. S.; Son, D.

1987-01-01

The exact Lorentz kinematics of the Thomas precession is discussed in terms of Wigner's O(3)-like little group which describes rotations in the Lorentz frame in which the particle is at rest. A Lorentz-covariant form for the Thomas factor is derived. It is shown that this factor is a Lorentz-boosted rotation matrix, which becomes a gauge transformation in the infinite-momentum or zero-mass limit.

Employing Lead Thiocyanate Additive to Reduce the Hysteresis and Boost the Fill Factor of Planar Perovskite Solar Cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ke, Weijun; Xiao, Chuanxiao; Wang, Changlei

2016-05-04

Lead thiocyanate in the perovskite precursor can increase the grain size of a perovskite thin film and reduce the conductivity of the grain boundaries, leading to perovskite solar cells with reduced hysteresis and enhanced fill factor. A planar perovskite solar cell with grain boundary and interface passivation achieves a steady-state efficiency of 18.42%.

Assessing the thermoelectric properties of single InSb nanowires: the role of thermal contact resistance

NASA Astrophysics Data System (ADS)

Yazji, S.; Swinkels, M. Y.; De Luca, M.; Hoffmann, E. A.; Ercolani, D.; Roddaro, S.; Abstreiter, G.; Sorba, L.; Bakkers, E. P. A. M.; Zardo, I.

2016-06-01

The peculiar shape and dimensions of nanowires (NWs) have opened the way to their exploitation in thermoelectric applications. In general, the parameters entering into the thermoelectric figure of merit are strongly interdependent, which makes it difficult to realize an optimal thermoelectric material. In NWs, instead, the power factor can be increased and the thermal conductivity reduced, thus boosting the thermoelectric efficiency compared to bulk materials. However, the assessment of all the thermoelectric properties of a NW is experimentally very challenging. Here, we focus on InSb NWs, which have proved to be promising thermoelectric materials. The figure of merit is accurately determined by using a novel method based on a combination of Raman spectroscopy and electrical measurements. Remarkably, this type of experiment provides a powerful approach allowing us to neglect the role played by thermal contact resistance. Furthermore, we compare the thermal conductivity determined by this novel method to the one determined on the same sample by the thermal bridge method. In this latter approach, the thermal contact resistance is a non-negligible parameter, especially in NWs with large diameters. We provide experimental evidence of the crucial role played by thermal contact resistance in the assessment of the thermal properties of nanostructures, using two different measurement methods of the thermal conductivity.

Applications technology satellites advanced mission study

NASA Technical Reports Server (NTRS)

Gould, L. M.

1972-01-01

Three spacecraft configurations were designed for operation as a high powered synchronous communications satellite. Each spacecraft includes a 1 kw TWT and a 2 kw Klystron power amplifier feeding an antenna with multiple shaped beams. One of the spacecraft is designed to be boosted by a Thor-Delta launch vehicle and raised to synchronous orbit with electric propulsion. The other two are inserted into a elliptical transfer orbit with an Atlas Centaur and injected into final orbit with an apogee kick motor. Advanced technologies employed in the several configurations include tubes with multiple stage collectors radiating directly to space, multiple-contoured beam antennas, high voltage rollout solar cell arrays with integral power conditioning, electric propulsion for orbit raising and on-station attitude control and station-keeping, and liquid metal slip rings.

Hybrid nanogenerator for concurrently harvesting biomechanical and biochemical energy.

PubMed

Hansen, Benjamin J; Liu, Ying; Yang, Rusen; Wang, Zhong Lin

2010-07-27

Harvesting energy from multiple sources available in our personal and daily environments is highly desirable, not only for powering personal electronics, but also for future implantable sensor-transmitter devices for biomedical and healthcare applications. Here we present a hybrid energy scavenging device for potential in vivo applications. The hybrid device consists of a piezoelectric poly(vinylidene fluoride) nanofiber nanogenerator for harvesting mechanical energy, such as from breathing or from the beat of a heart, and a flexible enzymatic biofuel cell for harvesting the biochemical (glucose/O2) energy in biofluid, which are two types of energy available in vivo. The two energy harvesting approaches can work simultaneously or individually, thereby boosting output and lifetime. Using the hybrid device, we demonstrate a "self-powered" nanosystem by powering a ZnO nanowire UV light sensor.

Friction forces on atoms after acceleration

DOE PAGES

Intravaia, Francesco; Mkrtchian, Vanik E.; Buhmann, Stefan Yoshi; ...

2015-05-12

The aim of this study is to revisit the calculation of atom–surface quantum friction in the quantum field theory formulation put forward by Barton (2010 New J. Phys. 12 113045). We show that the power dissipated into field excitations and the associated friction force depend on how the atom is boosted from being initially at rest to a configuration in which it is moving at constant velocity (v) parallel to the planar interface. In addition, we point out that there is a subtle cancellation between the one-photon and part of the two-photon dissipating power, resulting in a leading order contributionmore » to the frictional power which goes as v 4. These results are also confirmed by an alternative calculation of the average radiation force, which scales as v 3.« less

Optically-powered Voltage-supply-device for Effective Utilization of Optical Energy in the Fiber-To-The-Home Network

NASA Astrophysics Data System (ADS)

Fukano, Hideki; Shinagawa, Takeshi; Tsuruta, Kenji

An optically powered device with using InGaAs-Photodiode has been developed. This study aims to harvest light energy (2.8∼500μW) from the FTTH (Fiber To The Home) network and to utilize it for operating remote sensors without external energy sources. First, we designed and evaluated the characteristics of the booster circuit and confirmed that it could boost an input voltage of 0.3 V to 3.0 V. Next, we also evaluated the characteristics of InGaAs photodiode and confirmed that it can output a voltage over 0.3 V at 10-μW input light. We demonstrate that a ready-made sensor can be operated with an input optical power as low as 10 μW.

Lead-acid batteries in micro-hybrid applications. Part I. Selected key parameters

NASA Astrophysics Data System (ADS)

Schaeck, S.; Stoermer, A. O.; Kaiser, F.; Koehler, L.; Albers, J.; Kabza, H.

Micro-hybrid electric vehicles were launched by BMW in March 2007. These are equipped with brake energy regeneration (BER) and the automatic start and stop function (ASSF) of the internal combustion engine. These functions are based on common 14 V series components and lead-acid (LA) batteries. The novelty is given by the intelligent onboard energy management, which upgrades the conventional electric system to the micro-hybrid power system (MHPS). In part I of this publication the key factors for the operation of LA batteries in the MHPS are discussed. Especially for BER one is high dynamic charge acceptance (DCA) for effective boost charging. Vehicle rest time is identified as a particular negative parameter for DCA. It can be refreshed by regular fully charging at elevated charge voltage. Thus, the batteries have to be outstandingly robust against overcharge and water loss. This can be accomplished for valve-regulated lead-acid (VRLA) batteries at least if they are mounted in the trunk. ASSF goes along with frequent high-rate loads for warm cranking. The internal resistance determines the drop of the power net voltage during cranking and is preferably low for reasons of power net stability even after years of operation. Investigations have to be done with aged 90 Ah VRLA-absorbent glass mat (AGM) batteries. Battery operation at partial state-of-charge gives a higher risk of deep discharging (overdischarging). Subsequent re-charging then is likely to lead to the formation of micro-short circuits in the absorbent glass mat separator.

Manned space flight nuclear system safety. Volume 3: Reactor system preliminary nuclear safety analysis. Part 1: Reference Design Document (RDD)

NASA Technical Reports Server (NTRS)

1972-01-01

The Reference Design Document, of the Preliminary Safety Analysis Report (PSAR) - Reactor System provides the basic design and operations data used in the nuclear safety analysis of the Rector Power Module as applied to a Space Base program. A description of the power module systems, facilities, launch vehicle and mission operations, as defined in NASA Phase A Space Base studies is included. Each of two Zirconium Hydride Reactor Brayton power modules provides 50 kWe for the nominal 50 man Space Base. The INT-21 is the prime launch vehicle. Resupply to the 500 km orbit over the ten year mission is provided by the Space Shuttle. At the end of the power module lifetime (nominally five years), a reactor disposal system is deployed for boost into a 990 km high altitude (long decay time) earth orbit.

Analysis of transistor and snubber turn-off dynamics in high-frequency high-voltage high-power converters

NASA Technical Reports Server (NTRS)

Wilson, P. M.; Wilson, T. G.; Owen, H. A., Jr.

1982-01-01

Dc to dc converters which operate reliably and efficiently at switching frequencies high enough to effect substantial reductions in the size and weight of converter energy storage elements are studied. A two winding current or voltage stepup (buck boost) dc-to-dc converter power stage submodule designed to operate in the 2.5-kW range, with an input voltage range of 110 to 180 V dc, and an output voltage of 250 V dc is emphasized. In order to assess the limitations of present day component and circuit technologies, a design goal switching frequency of 10 kHz was maintained. The converter design requirements represent a unique combination of high frequency, high voltage, and high power operation. The turn off dynamics of the primary circuit power switching transistor and its associated turn off snubber circuitry are investigated.

Analysis of transistor and snubber turn-off dynamics in high-frequency high-voltage high-power converters

NASA Astrophysics Data System (ADS)

Wilson, P. M.; Wilson, T. G.; Owen, H. A., Jr.

Dc to dc converters which operate reliably and efficiently at switching frequencies high enough to effect substantial reductions in the size and weight of converter energy storage elements are studied. A two winding current or voltage stepup (buck boost) dc-to-dc converter power stage submodule designed to operate in the 2.5-kW range, with an input voltage range of 110 to 180 V dc, and an output voltage of 250 V dc is emphasized. In order to assess the limitations of present day component and circuit technologies, a design goal switching frequency of 10 kHz was maintained. The converter design requirements represent a unique combination of high frequency, high voltage, and high power operation. The turn off dynamics of the primary circuit power switching transistor and its associated turn off snubber circuitry are investigated.

Design Of An Electrical Flywheel For Surge Power Applications In Mobile Robots

NASA Astrophysics Data System (ADS)

Wright, David D.

1987-01-01

An energy boost system based on a flywheel has been designed to supply the surge power needs of mobile robots for operating equipment like transmitters, drills, manipulator arms, mobility augmenters, and etc. This flywheel increases the average power available from a battery, fuel cell, generator, RPG or solar array by one or more orders of magnitude for short periods. Flywheels can be charged and discharged for thousands of battery lifetimes. Flywheels can deliver more than ten times the power per unit weight of batteries. The electromechanical details of a reliable, energy efficient and (relatively) low cost flywheel are described. This flywheel is the combination of a highly efficient brushless motor and a laminated steel rotor operating in an hermetically sealed container with only electrical input and output. This design approach overcomes the inefficiencies generally associated with mechanically geared devices. Electrical round trip efficiency is 94% under optimum operating conditions.

A hybrid power system for unmanned aerial vehicle electromagnetic launcher

NASA Astrophysics Data System (ADS)

Wang, Zhiren; Wu, Jun; Huang, Shengjun

2018-06-01

According to the UAV electromagnetic catapult with fixed timing, a hybrid energy storage system consist with battery and super capacitor is designed, in order to reduce the volume and weight of the energy storage system. The battery is regarded as the energy storage device and the super capacitor as power release device. Firstly, the battery charges the super capacitor, and then the super capacitor supplies power to electromagnetic catapult separately. The strategy is using the Buck circuit to charge the super capacitor with constant current and using the Boost circuit to make super capacitor provide a stable voltage circuit for electromagnetic catapult. The Simulink simulation results show that the designed hybrid energy storage system can meet the requirements of electromagnetic catapult. Compared with the system powered by the battery alone, the proposed scheme can reduce the number of batteries, and greatly reduce the volume and weight of the energy storage system.

Cost-effectiveness assessment of lumpectomy cavity boost in elderly women with early stage estrogen receptor positive breast cancer receiving adjuvant radiotherapy.

PubMed

Lester-Coll, Nataniel H; Rutter, Charles E; Evans, Suzanne B

2016-04-01

Breast radiotherapy (RT) for elderly women with estrogen receptor positive early stage breast cancer (ER+ESBC) improves local recurrence (LR) rates without benefitting overall survival. Breast boost is a common practice, although the absolute benefit decreases with age. Consequently, an analysis of its cost-effectiveness in the elderly ESBC populations is warranted. A Markov model was used to compare cost-effectiveness of RT with or without a boost in elderly ER+ESBC patients. The ten-year probability of LR with boost was derived from the CALGB 9343 trial and adjusted by the hazard ratio for LR from boost radiotherapy trial data, yielding the LR rate without boost. Remaining parameters were estimated using published data. Boost RT was associated with an increase in mean cost ($7139 vs $6193) and effectiveness (5.66 vs 5.64 quality adjusted life years; QALYs) relative to no boost. The incremental cost-effectiveness ratio (ICER) for boost was $55,903 per QALY. On one-way sensitivity analysis, boost remained cost-effective if the hazard ratio of LR with boost was <0.67. Boost RT for ER+ESBC patients was cost-effective over a wide range of assumptions and inputs over commonly accepted willingness-to pay-thresholds, but particularly in women at higher risk for LR. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Genetic and Psychosocial Predictors of Aggression: Variable Selection and Model Building With Component-Wise Gradient Boosting.

PubMed

Suchting, Robert; Gowin, Joshua L; Green, Charles E; Walss-Bass, Consuelo; Lane, Scott D

2018-01-01

Rationale : Given datasets with a large or diverse set of predictors of aggression, machine learning (ML) provides efficient tools for identifying the most salient variables and building a parsimonious statistical model. ML techniques permit efficient exploration of data, have not been widely used in aggression research, and may have utility for those seeking prediction of aggressive behavior. Objectives : The present study examined predictors of aggression and constructed an optimized model using ML techniques. Predictors were derived from a dataset that included demographic, psychometric and genetic predictors, specifically FK506 binding protein 5 (FKBP5) polymorphisms, which have been shown to alter response to threatening stimuli, but have not been tested as predictors of aggressive behavior in adults. Methods : The data analysis approach utilized component-wise gradient boosting and model reduction via backward elimination to: (a) select variables from an initial set of 20 to build a model of trait aggression; and then (b) reduce that model to maximize parsimony and generalizability. Results : From a dataset of N = 47 participants, component-wise gradient boosting selected 8 of 20 possible predictors to model Buss-Perry Aggression Questionnaire (BPAQ) total score, with R 2 = 0.66. This model was simplified using backward elimination, retaining six predictors: smoking status, psychopathy (interpersonal manipulation and callous affect), childhood trauma (physical abuse and neglect), and the FKBP5_13 gene (rs1360780). The six-factor model approximated the initial eight-factor model at 99.4% of R 2 . Conclusions : Using an inductive data science approach, the gradient boosting model identified predictors consistent with previous experimental work in aggression; specifically psychopathy and trauma exposure. Additionally, allelic variants in FKBP5 were identified for the first time, but the relatively small sample size limits generality of results and calls for replication. This approach provides utility for the prediction of aggression behavior, particularly in the context of large multivariate datasets.

Targeting the Genital Tract Mucosa with a Lipopeptide/Recombinant Adenovirus Prime/Boost Vaccine Induces Potent and Long-Lasting CD8+ T Cell Immunity Against Herpes: Importance of Myeloid Differentiation Factor 881

PubMed Central

Zhang, Xiuli; Dervillez, Xavier; Chentoufi, Aziz Alami; Badakhshan, Tina; Bettahi, Ilham; BenMohamed, Lbachir

2012-01-01

Targeting the mucosal immune system of the genital tract (GT) with subunit vaccines failed to induce potent and durable local CD8+ T cell immunity, crucial for protection against many sexually transmitted viral (STV) pathogens, including herpes simplex virus type 2 (HSV-2) that causes genital herpes. In this study, we aimed to investigate the potential of a novel lipopeptide/adenovirus type 5 (Lipo/rAdv5) prime/boost mucosal vaccine for induction of CD8+ T cell immunity to protect the female genital tract from herpes. The lipopeptide and the rAdv5 vaccine express the immunodominant HSV-2 CD8+ T cell epitope (gB498-505) and both were delivered intravaginally (IVAG) in the progesterone-induced B6 mouse model of genital herpes. Compared to its homologous lipopeptide/lipopeptide (Lipo/Lipo); the Lipo/rAdv5 prime/boost immunized mice: (i) developed potent and sustained HSV-specific CD8+ T cells, detected in both the GT draining nodes (GT-DLN) and in the vaginal mucosa (VM); (ii) had significantly lower virus titers; (iii) had decreased overt signs of genital herpes disease; and (iv) did not succumb to lethal infection (p < 0.005), following intravaginal HSV-2 challenge. Polyfunctional CD8+ T cells, producing IFN-γ, TNF-α and IL-2 and exhibiting cytotoxic activity, were associated with protection (p < 0.005). The protective CD8+ T cell response was significantly compromised in the absence of the adaptor myeloid differentiation factor 88 (MyD88) (p = 0.0001). Taken together, these findings indicate that targeting the VM with a Lipo/rAdv5 prime/boost vaccine elicits a potent, MyD88-dependent, and long-lasting mucosal CD8+ T cell protective immunity against sexually transmitted herpes infection and disease. PMID:23018456

Examining the Draft Debate.

DTIC Science & Technology

1981-07-01

against conscription, and we believe them. A devotee of free- market economics is almost driven to ask, "What arguments can possibly be made in favor of...youth who are employed full time in the labor market . The report’s more detailed findings include the following: Two measures of socioeconomic...morale boosting power of upper middle class whites strike us as more than a little patronizing. We do need to maintain an adequate quality mix of Army

Development and Application of a Wireless, Networked Raspberry Pi Controlled Head Mounted Tactile Display (HMTD)

DTIC Science & Technology

2016-09-01

10 Fig. 8 Lithium ion polymer battery .................................................................. 11 Fig. 9 PowerBoost 1000C (right) and...7]. http://www.adafruit.com/products/1552. 7. Lithium Ion Polymer Battery –3.7v 2500mAh. [accessed Jul 7]. https://www.adafruit.com/products/328. 8...port directly) RealTek RT5370 Wi-Fi USB adapter 1 Wire-wrapping wires . . . Wire-wrap hand tool . . . Soldering kit . . . alipo: lithium - ion

Boosted dark matter and its implications for the features in IceCube HESE data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhattacharya, Atri; Gandhi, Raj; Gupta, Aritra

2017-05-01

We study the implications of the premise that any new, relativistic, highly energetic neutral particle that interacts with quarks and gluons would create cascade-like events in the IceCube (IC) detector. Such events would be observationally indistinguishable from neutral current deep-inelastic (DIS) scattering events due to neutrinos. Consequently, one reason for deviations, breaks or excesses in the expected astrophysical power-law neutrino spectrum could be the flux of such a particle. Motivated by features in the recent 1347-day IceCube high energy starting event (HESE) data, we focus on particular boosted dark matter (χ) related realizations of this premise. Here, χ is assumedmore » to be much lighter than, and the result of, the slow decay of a massive scalar (φ ) which constitutes a major fraction of the Universe's dark matter (DM) . We show that this hypothesis, coupled with a standard power-law astrophysical neutrino flux is capable of providing very good fits to the present data, along with a possible explanation of other features in the HESE sample. These features include a) the paucity of events beyond ∼ 2 PeV b) a spectral feature resembling a dip or a spectral change in the 400 TeV–1 PeV region and c) an excess in the 50−100 TeV region. We consider two different boosted DM scenarios, and determine the allowed mass ranges and couplings for four different types of mediators (scalar, pseudoscalar, vector and axial-vector) which could connect the standard and dark sectors.We consider constraints from gamma-ray observations and collider searches. We find that the gamma-ray observations provide the most restrictive constraints, disfavouring the 1σ allowed parameter space from IC fits, while still being consistent with the 3σ allowed region. We also test our proposal and its implications against the (statistically independent) sample of six year through-going muon track data recently released by IceCube.« less

Can you boost your metabolism?

MedlinePlus

Weight-loss boost metabolism; Obesity - boost metabolism; Overweight - boost metabolism ... Cowley MA, Brown WA, Considine RV. Obesity. In: Jameson JL, De Groot ... and Pediatric . 7th ed. Philadelphia, PA: Elsevier Saunders; ...

What You Can Do to Boost America's Productivity.

ERIC Educational Resources Information Center

Radvany, John E.

1979-01-01

Discusses factors contributing to the declining U.S. productivity growth rate and compares U.S. production to Germany and Japan. Presents model programs that have recognized the need to develop in people the desire to work, study, improve, and become more productive citizens. (LRA)

Observation of Enhanced Hole Extraction in Br Concentration Gradient Perovskite Materials.

PubMed

Kim, Min-Cheol; Kim, Byeong Jo; Son, Dae-Yong; Park, Nam-Gyu; Jung, Hyun Suk; Choi, Mansoo

2016-09-14

Enhancing hole extraction inside the perovskite layer is the key factor for boosting photovoltaic performance. Realization of halide concentration gradient perovskite materials has been expected to exhibit rapid hole extraction due to the precise bandgap tuning. Moreover, a formation of Br-rich region on the tri-iodide perovskite layer is expected to enhance moisture stability without a loss of current density. However, conventional synthetic techniques of perovskite materials such as the solution process have not achieved the realization of halide concentration gradient perovskite materials. In this report, we demonstrate the fabrication of Br concentration gradient mixed halide perovskite materials using a novel and facile halide conversion method based on vaporized hydrobromic acid. Accelerated hole extraction and enhanced lifetime due to Br gradient was verified by observing photoluminescence properties. Through the combination of secondary ion mass spectroscopy and transmission electron microscopy with energy-dispersive X-ray spectroscopy analysis, the diffusion behavior of Br ions in perovskite materials was investigated. The Br-gradient was found to be eventually converted into a homogeneous mixed halide layer after undergoing an intermixing process. Br-substituted perovskite solar cells exhibited a power conversion efficiency of 18.94% due to an increase in open circuit voltage from 1.08 to 1.11 V and an advance in fill-factor from 0.71 to 0.74. Long-term stability was also dramatically enhanced after the conversion process, i.e., the power conversion efficiency of the post-treated device has remained over 97% of the initial value under high humid conditions (40-90%) without any encapsulation for 4 weeks.

Radiation Effects on DC-DC Converters

NASA Technical Reports Server (NTRS)

Zhang, De-Xin; AbdulMazid, M. D.; Attia, John O.; Kankam, Mark D. (Technical Monitor)

2001-01-01

In this work, several DC-DC converters were designed and built. The converters are Buck Buck-Boost, Cuk, Flyback, and full-bridge zero-voltage switched. The total ionizing dose radiation and single event effects on the converters were investigated. The experimental results for the TID effects tests show that the voltages of the Buck Buck-Boost, Cuk, and Flyback converters increase as total dose increased when using power MOSFET IRF250 as a switching transistor. The change in output voltage with total dose is highest for the Buck converter and the lowest for Flyback converter. The trend of increase in output voltages with total dose in the present work agrees with those of the literature. The trends of the experimental results also agree with those obtained from PSPICE simulation. For the full-bridge zero-voltage switch converter, it was observed that the dc-dc converter with IRF250 power MOSFET did not show a significant change of output voltage with total dose. In addition, for the dc-dc converter with FSF254R4 radiation-hardened power MOSFET, the output voltage did not change significantly with total dose. The experimental results were confirmed by PSPICE simulation that showed that FB-ZVS converter with IRF250 power MOSFET's was not affected with the increase in total ionizing dose. Single Event Effects (SEE) radiation tests were performed on FB-ZVS converters. It was observed that the FB-ZVS converter with the IRF250 power MOSFET, when the device was irradiated with Krypton ion with ion-energy of 150 MeV and LET of 41.3 MeV-square cm/mg, the output voltage increased with the increase in fluence. However, for Krypton with ion-energy of 600 MeV and LET of 33.65 MeV-square cm/mg, and two out of four transistors of the converter were permanently damaged. The dc-dc converter with FSF254R4 radiation hardened power MOSFET's did not show significant change at the output voltage with fluence while being irradiated by Krypton with ion energy of 1.20 GeV and LET of 25.97 MeV-square cm/mg. This might be due to fact that the device is radiation hardened.

Design of a high voltage input - output ratio dc-dc converter dedicated to small power fuel cell systems

NASA Astrophysics Data System (ADS)

Béthoux, O.; Cathelin, J.

2010-12-01

Consuming chemical energy, fuel cells produce simultaneously heat, water and useful electrical power [J.M. Andújar, F. Segura, Renew. Sust. Energy Rev. 13, 2309 (2009)], [J. Larminie, A. Dicks, Fuel Cell Systems Explained, 2nd edn. (John Wiley & Sons, 2003)]. As a matter of fact, the voltage generated by a fuel cell strongly depends on both the load power demand and the operating conditions. Besides, as a result of many design aspects, fuel cells are low voltage and high current electric generators. On the contrary, electric loads are commonly designed for small voltage swing and a high V/I ratio in order to minimize Joule losses. Therefore, electric loads supplied by fuel cells are typically fed by means of an intermediate power voltage regulator. The specifications of such a power converter are to be able to step up the input voltage with a high ratio (a ratio of 10 is a classic situation) and also to work with an excellent efficiency (in order to minimize its size, its weight and its losses) [A. Shahin, B. Huang, J.P. Martin, S. Pierfederici, B. Davat, Energy Conv. Manag. 51, 56 (2010)]. This paper deals with the design of this essential ancillary device. It intends to bring out the best structure for fulfilling this function. Several dc-dc converters with large voltage step-up ratios are introduced. A topology based on a coupled inductor or tapped inductor is closely studied. A detailed modelling is performed with the purpose of providing designing rules. This model is validated with both simulation and implementation. The experimental prototype is based on the following specifications: the fuel cell output voltage ranges from a 50 V open-voltage to a 25 V rated voltage while the load requires a constant 250 V voltage. The studied coupled inductor converter is compared with a classic boost converter commonly used in this voltage elevating application. Even though the voltage regulator faces severe FC specifications, the measured efficiency reaches 96% at the rated power whereas conventional boost efficiency barely achieves 91.5% in the same operating conditions.

Bag-of-features based medical image retrieval via multiple assignment and visual words weighting.

PubMed

Wang, Jingyan; Li, Yongping; Zhang, Ying; Wang, Chao; Xie, Honglan; Chen, Guoling; Gao, Xin

2011-11-01

Bag-of-features based approaches have become prominent for image retrieval and image classification tasks in the past decade. Such methods represent an image as a collection of local features, such as image patches and key points with scale invariant feature transform (SIFT) descriptors. To improve the bag-of-features methods, we first model the assignments of local descriptors as contribution functions, and then propose a novel multiple assignment strategy. Assuming the local features can be reconstructed by their neighboring visual words in a vocabulary, reconstruction weights can be solved by quadratic programming. The weights are then used to build contribution functions, resulting in a novel assignment method, called quadratic programming (QP) assignment. We further propose a novel visual word weighting method. The discriminative power of each visual word is analyzed by the sub-similarity function in the bin that corresponds to the visual word. Each sub-similarity function is then treated as a weak classifier. A strong classifier is learned by boosting methods that combine those weak classifiers. The weighting factors of the visual words are learned accordingly. We evaluate the proposed methods on medical image retrieval tasks. The methods are tested on three well-known data sets, i.e., the ImageCLEFmed data set, the 304 CT Set, and the basal-cell carcinoma image set. Experimental results demonstrate that the proposed QP assignment outperforms the traditional nearest neighbor assignment, the multiple assignment, and the soft assignment, whereas the proposed boosting based weighting strategy outperforms the state-of-the-art weighting methods, such as the term frequency weights and the term frequency-inverse document frequency weights.

Free Energy Perturbation Hamiltonian Replica-Exchange Molecular Dynamics (FEP/H-REMD) for Absolute Ligand Binding Free Energy Calculations.

PubMed

Jiang, Wei; Roux, Benoît

2010-07-01

Free Energy Perturbation with Replica Exchange Molecular Dynamics (FEP/REMD) offers a powerful strategy to improve the convergence of free energy computations. In particular, it has been shown previously that a FEP/REMD scheme allowing random moves within an extended replica ensemble of thermodynamic coupling parameters "lambda" can improve the statistical convergence in calculations of absolute binding free energy of ligands to proteins [J. Chem. Theory Comput. 2009, 5, 2583]. In the present study, FEP/REMD is extended and combined with an accelerated MD simulations method based on Hamiltonian replica-exchange MD (H-REMD) to overcome the additional problems arising from the existence of kinetically trapped conformations within the protein receptor. In the combined strategy, each system with a given thermodynamic coupling factor lambda in the extended ensemble is further coupled with a set of replicas evolving on a biased energy surface with boosting potentials used to accelerate the inter-conversion among different rotameric states of the side chains in the neighborhood of the binding site. Exchanges are allowed to occur alternatively along the axes corresponding to the thermodynamic coupling parameter lambda and the boosting potential, in an extended dual array of coupled lambda- and H-REMD simulations. The method is implemented on the basis of new extensions to the REPDSTR module of the biomolecular simulation program CHARMM. As an illustrative example, the absolute binding free energy of p-xylene to the nonpolar cavity of the L99A mutant of T4 lysozyme was calculated. The tests demonstrate that the dual lambda-REMD and H-REMD simulation scheme greatly accelerates the configurational sampling of the rotameric states of the side chains around the binding pocket, thereby improving the convergence of the FEP computations.

Big power from walking

NASA Astrophysics Data System (ADS)

Illenberger, Patrin K.; Madawala, Udaya K.; Anderson, Iain A.

2016-04-01

Dielectric Elastomer Generators (DEG) offer an opportunity to capture the energy otherwise wasted from human motion. By integrating a DEG into the heel of standard footwear, it is possible to harness this energy to power portable devices. DEGs require substantial auxiliary systems which are commonly large, heavy and inefficient. A unique challenge for these low power generators is the combination of high voltage and low current. A void exists in the semiconductor market for devices that can meet these requirements. Until these become available, existing devices must be used in an innovative way to produce an effective DEG system. Existing systems such as the Bi-Directional Flyback (BDFB) and Self Priming Circuit (SPC) are an excellent example of this. The BDFB allows full charging and discharging of the DEG, improving power gained. The SPC allows fully passive voltage boosting, removing the priming source and simplifying the electronics. This paper outlines the drawbacks and benefits of active and passive electronic solutions for maximizing power from walking.

Boosted Regression Tree Models to Explain Watershed ...

EPA Pesticide Factsheets

Boosted regression tree (BRT) models were developed to quantify the nonlinear relationships between landscape variables and nutrient concentrations in a mesoscale mixed land cover watershed during base-flow conditions. Factors that affect instream biological components, based on the Index of Biotic Integrity (IBI), were also analyzed. Seasonal BRT models at two spatial scales (watershed and riparian buffered area [RBA]) for nitrite-nitrate (NO2-NO3), total Kjeldahl nitrogen, and total phosphorus (TP) and annual models for the IBI score were developed. Two primary factors — location within the watershed (i.e., geographic position, stream order, and distance to a downstream confluence) and percentage of urban land cover (both scales) — emerged as important predictor variables. Latitude and longitude interacted with other factors to explain the variability in summer NO2-NO3 concentrations and IBI scores. BRT results also suggested that location might be associated with indicators of sources (e.g., land cover), runoff potential (e.g., soil and topographic factors), and processes not easily represented by spatial data indicators. Runoff indicators (e.g., Hydrological Soil Group D and Topographic Wetness Indices) explained a substantial portion of the variability in nutrient concentrations as did point sources for TP in the summer months. The results from our BRT approach can help prioritize areas for nutrient management in mixed-use and heavily impacted watershed

SU-E-J-124: 18F-FDG PET Imaging to Improve RT Treatment Outcome for Locally Advanced Lung Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shusharina, N; Khan, F; Sharp, G

2015-06-15

Purpose: To investigate spatial correlation between high uptake regions of pre- and 10-days-post therapy{sup 1} {sup 8}F-FDG PET in recurrent lung cancer and to evaluate the feasibility of dose escalation boosting only regions with high FDG uptake identified on baseline PET. Methods: Nineteen patients with stages II– IV inoperable lung cancer were selected. Volumes of interest (VOI) on pre-therapy FDG-PET were defined using an isocontour at ≥50% of SUVmax. VOI of pre- and post-therapy PET images were correlated for the extent of overlap. A highly optimized IMRT plan to 60 Gy prescribed to PTV defined on the planning CT wasmore » designed using clinical dose constraints for the organs at risk. A boost of 18 Gy was prescribed to the VOI defined on baseline PET. A composite plan of the total 78 Gy was compared with the base 60 Gy plan. Increases in dose to the lungs, spinal cord and heart were evaluated. IMRT boost plan was compared with proton RT and SBRT boost plans. Results: Overlap fraction of baseline PET VOI with the VOI on 10 days-post therapy PET was 0.8 (95% CI: 0.7 – 0.9). Using baseline VOI as a boosting volume, dose could be escalated to 78 Gy for 15 patients without compromising the dose constraints. For 4 patients, the dose limiting factors were V20Gy and Dmean for the total lung, and Dmax for the spinal cord. An increase of the dose to OARs correlated significantly with the relative size of the boost volume. Conclusion: VOI defined on baseline 18F-FDG PET by the SUVmax-≥50% isocontour may be a biological target volume for escalated radiation dose. Dose escalation to this volume may provide improved tumor control without breaching predefined dose constraints for OARs. The best treatment outcome may be achieved with proton RT for large targets and with SBRT for small targets.« less

Jet pump-drive system for heat removal

NASA Technical Reports Server (NTRS)

French, J. R. (Inventor)

1985-01-01

A jet pump, in combination with a TEMP, is employed to assure safe cooling of a nuclear reactor after shutdown. A TEMP, responsive to the heat from the coolant in the secondary flow path, automatically pumps the withdrawn coolant to a higher pressure and thus higher velocity compared to the main flow. The high velocity coolant is applied as a driver flow for the jet pump which has a main flow chamber located in the main flow circulation pump. Upon nuclear shutdown and loss of power for the main reactor pumping system, the TEMP/jet pump combination continues to boost the coolant flow in the direction it is already circulating. During the decay time for the nuclear reactor, the jet pump keeps running until the coolant temperature drops to a lower and safe temperature. At this lower temperature, the TEMP/jet jump combination ceases its circulation boosting operation. The TEMP/jet pump combination is automatic, self-regulating and provides an emergency pumping system free of moving parts.

A 0.9-V 12-bit 40-MSPS Pipeline ADC for Wireless Receivers

NASA Astrophysics Data System (ADS)

Ito, Tomohiko; Itakura, Tetsuro

A 0.9-V 12-bit 40-MSPS pipeline ADC with I/Q amplifier sharing technique is presented for wireless receivers. To achieve high linearity even at 0.9-V supply, the clock signals to sampling switches are boosted over 0.9V in conversion stages. The clock-boosting circuit for lifting these clocks is shared between I-ch ADC and Q-ch ADC, reducing the area penalty. Low supply voltage narrows the available output range of the operational amplifier. A pseudo-differential (PD) amplifier with two-gain-stage common-mode feedback (CMFB) is proposed in views of its wide output range and power efficiency. This ADC is fabricated in 90-nm CMOS technology. At 40MS/s, the measured SNDR is 59.3dB and the corresponding effective number of bits (ENOB) is 9.6. Until Nyquist frequency, the ENOB is kept over 9.3. The ADC dissipates 17.3mW/ch, whose performances are suitable for ADCs for mobile wireless systems such as WLAN/WiMAX.

Pulsed Direct Current Electrospray: Enabling Systematic Analysis of Small Volume Sample by Boosting Sample Economy.

PubMed

Wei, Zhenwei; Xiong, Xingchuang; Guo, Chengan; Si, Xingyu; Zhao, Yaoyao; He, Muyi; Yang, Chengdui; Xu, Wei; Tang, Fei; Fang, Xiang; Zhang, Sichun; Zhang, Xinrong

2015-11-17

We had developed pulsed direct current electrospray ionization mass spectrometry (pulsed-dc-ESI-MS) for systematically profiling and determining components in small volume sample. Pulsed-dc-ESI utilized constant high voltage to induce the generation of single polarity pulsed electrospray remotely. This method had significantly boosted the sample economy, so as to obtain several minutes MS signal duration from merely picoliter volume sample. The elongated MS signal duration enable us to collect abundant MS(2) information on interested components in a small volume sample for systematical analysis. This method had been successfully applied for single cell metabolomics analysis. We had obtained 2-D profile of metabolites (including exact mass and MS(2) data) from single plant and mammalian cell, concerning 1034 components and 656 components for Allium cepa and HeLa cells, respectively. Further identification had found 162 compounds and 28 different modification groups of 141 saccharides in a single Allium cepa cell, indicating pulsed-dc-ESI a powerful tool for small volume sample systematical analysis.

Glutamatergic drive along the septo-temporal axis of hippocampus boosts prelimbic oscillations in the neonatal mouse

PubMed Central

Ahlbeck, Joachim; Song, Lingzhen; Chini, Mattia; Bitzenhofer, Sebastian H

2018-01-01

The long-range coupling within prefrontal-hippocampal networks that account for cognitive performance emerges early in life. The discontinuous hippocampal theta bursts have been proposed to drive the generation of neonatal prefrontal oscillations, yet the cellular substrate of these early interactions is still unresolved. Here, we selectively target optogenetic manipulation of glutamatergic projection neurons in the CA1 area of either dorsal or intermediate/ventral hippocampus at neonatal age to elucidate their contribution to the emergence of prefrontal oscillatory entrainment. We show that despite stronger theta and ripples power in dorsal hippocampus, the prefrontal cortex is mainly coupled with intermediate/ventral hippocampus by phase-locking of neuronal firing via dense direct axonal projections. Theta band-confined activation by light of pyramidal neurons in intermediate/ventral but not dorsal CA1 that were transfected by in utero electroporation with high-efficiency channelrhodopsin boosts prefrontal oscillations. Our data causally elucidate the cellular origin of the long-range coupling in the developing brain. PMID:29631696

The Long Shadow of Rivalry: Rivalry Motivates Performance Today and Tomorrow.

PubMed

Pike, Brian E; Kilduff, Gavin J; Galinsky, Adam D

2018-05-01

Research has established that competing head to head against a rival boosts motivation and performance. The present research investigated whether rivalry can affect performance over time and in contests without rivals. We examined the long-term effects of rivalry through archival analyses of postseason performance in multiple high-stakes sports contexts: National Collegiate Athletic Association (NCAA) Division I Men's Basketball and the major U.S. professional sports leagues: National Basketball Association (NBA), National Football League (NFL), Major League Baseball (MLB), and National Hockey League (NHL). Econometric analyses revealed that postseason performance of a focal team's rival in year N predicted that focal team's postseason performance in year N + 1. Follow-up analyses suggested that the performance boost was especially pronounced when one's rival won the previous tournament. These results establish that rivalry has a long shadow: A rival team's success exerts such a powerful motivational force that it drives performance outside of direct competition with one's rival and even after a significant delay.

A Study on Electric Power Smoothing System for Lead-Acid Battery of Stand-Alone Natural Energy Power System Using EDLC

NASA Astrophysics Data System (ADS)

Jia, Yan; Shibata, Ryosuke; Yamamura, Naoki; Ishida, Muneaki

To resolve energy shortage and global warming problem, renewable natural resource and its power system has been gradually generalizing. However, the power fluctuation suppressing in short period and the balance control of consumption and supply in long period are two of main problems that need to be resolved urgently in natural energy power system. In Stand-alone Natural Energy Power System (SNEPS) with power energy storage devices, power fluctuation in short period is one of the main reasons that recharge cycle times increase and lead-acid battery early failure. Hence, to prolong the service life of lead-acid battery and improve power quality through suppressing the power fluctuation, we proposed a method of electric power smoothing for lead-acid battery of SNEPS using bi-directional Buck/Boost converter and Electric Double Layer Capacitor (EDLC) in this paper. According to the test data of existing SNEPS, a power fluctuation condition is selected and as an example to analyze the validity of the proposed method. The analysis of frequency characteristics indicates the power fluctuation is suppressed a desired range in the target frequency region. The experimental results of confirmed the feasibility of the proposed system and the results well satisfy the requirement of system design.

Parenting practices and the development of adolescents' social trust.

PubMed

Wray-Lake, Laura; Flanagan, Constance A

2012-06-01

Social trust (ST) (i.e., beliefs that people are generally fair and trustworthy) is a critical disposition for democratic governance. Yet there has been scant research on its developmental foundations. We assess factors related to ST in 11-18 year olds with survey data collected over two years from 1150 U.S. adolescents and their mothers. Adolescents' ST in year 1 and their reports of a positive neighborhood climate predicted ST one year later. Adolescents' reports of family practices were stronger predictors of their ST than were mothers' reports. Regression analyses revealed different factors predicting changes in ST for three adolescent age groups: With ST at T1 and background factors controlled, democratic parenting boosted ST for early- and middle-adolescents. Adolescents' reports that parents encouraged compassion for others boosted ST for middle- and late-adolescents, and parental cautions about other people taking advantage diminished ST among middle adolescents. Results suggest that the disposition to trust others is formed, in part, by what adolescents hear from parents about their responsibilities to fellow human beings and by modeling of democratic parenting. Copyright © 2011 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

Boost the electron mobility of solution-grown organic single crystals via reducing the amount of polar solvent residues

DOE PAGES

Xue, Guobiao; Xin, Huolin L.; Wu, Jiake; ...

2015-10-29

Enhancing electron transport to match with the development in hole transport is critical for organic electronics in the future. As electron motion is susceptible to extrinsic factors, seeking these factors and avoiding their negative effects have become the central challenge. Here, the existence of polar solvent residues in solution-grown single-crystals of 6,13-bis(triisopropylsilylethynyl)-5,7,12,14-tetraazapentacene is identified as a factor detrimental to electron motion. Field-effect transistors of the crystals exhibit electron mobility boosted by about 60% after the residues are removed. The average electron mobility reaches up to 8.0 ± 2.2 cm 2 V –1 s –1 with a highest value of 13.3more » cm 2 V –1 s –1; these results are significantly higher than those obtained previously for the same molecule (1.0–5.0 cm 2 V –1 s –1). Furthermore, the achieved mobility is also higher than the maximum reported electron mobility for organic materials (11 cm 2 V –1 s –1). As a result, this work should greatly accelerate the advancement of organic electron-transporting materials.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shusharina, N; Khan, F; Sharp, G

Purpose: To determine the dose level and timing of the boost in locally advanced lung cancer patients with confirmed tumor recurrence by comparing different boosting strategies by an impact of dose escalation in improvement of the therapeutic ratio. Methods: We selected eighteen patients with advanced NSCLC and confirmed recurrence. For each patient, a base IMRT plan to 60 Gy prescribed to PTV was created. Then we compared three dose escalation strategies: a uniform escalation to the original PTV, an escalation to a PET-defined target planned sequentially and concurrently. The PET-defined targets were delineated by biologically-weighed regions on a pre-treatment 18F-FDGmore » PET. The maximal achievable dose, without violating the OAR constraints, was identified for each boosting method. The EUD for the target, spinal cord, combined lung, and esophagus was compared for each plan. Results: The average prescribed dose was 70.4±13.9 Gy for the uniform boost, 88.5±15.9 Gy for the sequential boost and 89.1±16.5 Gy for concurrent boost. The size of the boost planning volume was 12.8% (range: 1.4 – 27.9%) of the PTV. The most prescription-limiting dose constraints was the V70 of the esophagus. The EUD within the target increased by 10.6 Gy for the uniform boost, by 31.4 Gy for the sequential boost and by 38.2 for the concurrent boost. The EUD for OARs increased by the following amounts: spinal cord, 3.1 Gy for uniform boost, 2.8 Gy for sequential boost, 5.8 Gy for concurrent boost; combined lung, 1.6 Gy for uniform, 1.1 Gy for sequential, 2.8 Gy for concurrent; esophagus, 4.2 Gy for uniform, 1.3 Gy for sequential, 5.6 Gy for concurrent. Conclusion: Dose escalation to a biologically-weighed gross tumor volume defined on a pre-treatment 18F-FDG PET may provide improved therapeutic ratio without breaching predefined OAR constraints. Sequential boost provides better sparing of OARs as compared with concurrent boost.« less

Nonrelativistic Yang-Mills theory for a naturally light Higgs boson

NASA Astrophysics Data System (ADS)

Berthier, Laure; Grosvenor, Kevin T.; Yan, Ziqi

2017-11-01

We continue the study of the nonrelativistic short-distance completions of a naturally light Higgs, focusing on the interplay between the gauge symmetries and the polynomial shift symmetries. We investigate the naturalness of nonrelativistic scalar quantum electrodynamics with a dynamical critical exponent z =3 by computing leading power law divergences to the scalar propagator in this theory. We find that power law divergences exhibit a more refined structure in theories that lack boost symmetries. Finally, in this toy model, we show that it is possible to preserve a fairly large hierarchy between the scalar mass and the high-energy naturalness scale across 7 orders of magnitude, while accommodating a gauge coupling of order 0.1.

Boosting the power conversion efficiency of perovskite solar cells using self-organized polymeric hole extraction layers with high work function.

PubMed

Lim, Kyung-Geun; Kim, Hak-Beom; Jeong, Jaeki; Kim, Hobeom; Kim, Jin Young; Lee, Tae-Woo

2014-10-08

A self-organized hole extraction layer (SOHEL) with high work function (WF) is designed for energy level alignment with the ionization potential level of CH3 NH3 PbI3 . The SOHEL increases the built-in potential, photocurrent, and power conversion efficiency (PCE) of CH3 NH3 PbI3 perovskite solar cells. Thus, interface engineering of the positive electrode of solution-processed planar heterojunction solar cells using a high-WF SOHEL is a very effective way to achieve high device efficiency (PCE = 11.7% on glass). © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Space shuttle guidance, navigation, and control design equations. Volume 3: Guidance

NASA Technical Reports Server (NTRS)

1973-01-01

Space shuttle guidance, navigation, and control design equations are presented. The space-shuttle mission includes three relatively distinct guidance phases which are discussed; atmospheric boost, which is characterized by an adaptive guidance law; extra-atmospheric activities; and re-entry activities, where aerodynamic surfaces are the principal effectors. Guidance tasks include pre-maneuver targeting and powered flight guidance, where powered flight is defined to include the application of aerodynamic forces as well as thruster forces. A flow chart which follows guidance activities throughout the mission from the pre-launch phase through touchdown is presented. The main guidance programs and subroutines used in each phase of a typical rendezvous mission are listed. Detailed software requirements are also presented.

A new method to distinguish hadronically decaying boosted Z bosons from W bosons using the ATLAS detector

NASA Astrophysics Data System (ADS)

Aad, G.; Abbott, B.; Abdallah, J.; Abdinov, O.; Aben, R.; Abolins, M.; AbouZeid, O. S.; Abramowicz, H.; Abreu, H.; Abreu, R.; Abulaiti, Y.; Acharya, B. S.; Adamczyk, L.; Adams, D. L.; Adelman, J.; Adomeit, S.; Adye, T.; Affolder, A. A.; Agatonovic-Jovin, T.; Agricola, J.; Aguilar-Saavedra, J. A.; Ahlen, S. P.; Ahmadov, F.; Aielli, G.; Akerstedt, H.; Åkesson, T. P. A.; Akimov, A. V.; Alberghi, G. L.; Albert, J.; Albrand, S.; Alconada Verzini, M. J.; Aleksa, M.; Aleksandrov, I. N.; Alexa, C.; Alexander, G.; Alexopoulos, T.; Alhroob, M.; Alimonti, G.; Alio, L.; Alison, J.; Alkire, S. P.; Allbrooke, B. M. M.; Allport, P. P.; Aloisio, A.; Alonso, A.; Alonso, F.; Alpigiani, C.; Altheimer, A.; Alvarez Gonzalez, B.; Álvarez Piqueras, D.; Alviggi, M. G.; Amadio, B. T.; Amako, K.; Amaral Coutinho, Y.; Amelung, C.; Amidei, D.; Amor Dos Santos, S. P.; Amorim, A.; Amoroso, S.; Amram, N.; Amundsen, G.; Anastopoulos, C.; Ancu, L. S.; Andari, N.; Andeen, T.; Anders, C. F.; Anders, G.; Anders, J. K.; Anderson, K. J.; Andreazza, A.; Andrei, V.; Angelidakis, S.; Angelozzi, I.; Anger, P.; Angerami, A.; Anghinolfi, F.; Anisenkov, A. V.; Anjos, N.; Annovi, A.; Antonelli, M.; Antonov, A.; Antos, J.; Anulli, F.; Aoki, M.; Aperio Bella, L.; Arabidze, G.; Arai, Y.; Araque, J. P.; Arce, A. T. H.; Arduh, F. A.; Arguin, J.-F.; Argyropoulos, S.; Arik, M.; Armbruster, A. J.; Arnaez, O.; Arnal, V.; Arnold, H.; Arratia, M.; Arslan, O.; Artamonov, A.; Artoni, G.; Asai, S.; Asbah, N.; Ashkenazi, A.; Åsman, B.; Asquith, L.; Assamagan, K.; Astalos, R.; Atkinson, M.; Atlay, N. B.; Augsten, K.; Aurousseau, M.; Avolio, G.; Axen, B.; Ayoub, M. K.; Azuelos, G.; Baak, M. A.; Baas, A. E.; Baca, M. J.; Bacci, C.; Bachacou, H.; Bachas, K.; Backes, M.; Backhaus, M.; Bagiacchi, P.; Bagnaia, P.; Bai, Y.; Bain, T.; Baines, J. T.; Baker, O. K.; Baldin, E. M.; Balek, P.; Balestri, T.; Balli, F.; Balunas, W. K.; Banas, E.; Banerjee, Sw.; Bannoura, A. A. E.; Bansil, H. S.; Barak, L.; Barberio, E. L.; Barberis, D.; Barbero, M.; Barillari, T.; Barisonzi, M.; Barklow, T.; Barlow, N.; Barnes, S. L.; Barnett, B. M.; Barnett, R. M.; Barnovska, Z.; Baroncelli, A.; Barone, G.; Barr, A. J.; Barreiro, F.; Barreiro Guimarães da Costa, J.; Bartoldus, R.; Barton, A. E.; Bartos, P.; Basalaev, A.; Bassalat, A.; Basye, A.; Bates, R. L.; Batista, S. J.; Batley, J. R.; Battaglia, M.; Bauce, M.; Bauer, F.; Bawa, H. S.; Beacham, J. B.; Beattie, M. D.; Beau, T.; Beauchemin, P. H.; Beccherle, R.; Bechtle, P.; Beck, H. P.; Becker, K.; Becker, M.; Beckingham, M.; Becot, C.; Beddall, A. J.; Beddall, A.; Bednyakov, V. A.; Bee, C. P.; Beemster, L. J.; Beermann, T. A.; Begel, M.; Behr, J. K.; Belanger-Champagne, C.; Bell, W. H.; Bella, G.; Bellagamba, L.; Bellerive, A.; Bellomo, M.; Belotskiy, K.; Beltramello, O.; Benary, O.; Benchekroun, D.; Bender, M.; Bendtz, K.; Benekos, N.; Benhammou, Y.; Benhar Noccioli, E.; Benitez Garcia, J. A.; Benjamin, D. P.; Bensinger, J. R.; Bentvelsen, S.; Beresford, L.; Beretta, M.; Berge, D.; Bergeaas Kuutmann, E.; Berger, N.; Berghaus, F.; Beringer, J.; Bernard, C.; Bernard, N. R.; Bernius, C.; Bernlochner, F. U.; Berry, T.; Berta, P.; Bertella, C.; Bertoli, G.; Bertolucci, F.; Bertsche, C.; Bertsche, D.; Besana, M. I.; Besjes, G. J.; Bessidskaia Bylund, O.; Bessner, M.; Besson, N.; Betancourt, C.; Bethke, S.; Bevan, A. J.; Bhimji, W.; Bianchi, R. M.; Bianchini, L.; Bianco, M.; Biebel, O.; Biedermann, D.; Bieniek, S. P.; Biglietti, M.; Bilbao De Mendizabal, J.; Bilokon, H.; Bindi, M.; Binet, S.; Bingul, A.; Bini, C.; Biondi, S.; Black, C. W.; Black, J. E.; Black, K. M.; Blackburn, D.; Blair, R. E.; Blanchard, J.-B.; Blanco, J. E.; Blazek, T.; Bloch, I.; Blocker, C.; Blum, W.; Blumenschein, U.; Bobbink, G. J.; Bobrovnikov, V. S.; Bocchetta, S. S.; Bocci, A.; Bock, C.; Boehler, M.; Bogaerts, J. A.; Bogavac, D.; Bogdanchikov, A. G.; Bohm, C.; Boisvert, V.; Bold, T.; Boldea, V.; Boldyrev, A. S.; Bomben, M.; Bona, M.; Boonekamp, M.; Borisov, A.; Borissov, G.; Borroni, S.; Bortfeldt, J.; Bortolotto, V.; Bos, K.; Boscherini, D.; Bosman, M.; Boudreau, J.; Bouffard, J.; Bouhova-Thacker, E. V.; Boumediene, D.; Bourdarios, C.; Bousson, N.; Boveia, A.; Boyd, J.; Boyko, I. R.; Bozic, I.; Bracinik, J.; Brandt, A.; Brandt, G.; Brandt, O.; Bratzler, U.; Brau, B.; Brau, J. E.; Braun, H. M.; Brazzale, S. F.; Breaden Madden, W. D.; Brendlinger, K.; Brennan, A. J.; Brenner, L.; Brenner, R.; Bressler, S.; Bristow, K.; Bristow, T. M.; Britton, D.; Britzger, D.; Brochu, F. M.; Brock, I.; Brock, R.; Bronner, J.; Brooijmans, G.; Brooks, T.; Brooks, W. K.; Brosamer, J.; Brost, E.; Brown, J.; Bruckman de Renstrom, P. A.; Bruncko, D.; Bruneliere, R.; Bruni, A.; Bruni, G.; Bruschi, M.; Bruscino, N.; Bryngemark, L.; Buanes, T.; Buat, Q.; Buchholz, P.; Buckley, A. G.; Buda, S. I.; Budagov, I. A.; Buehrer, F.; Bugge, L.; Bugge, M. K.; Bulekov, O.; Bullock, D.; Burckhart, H.; Burdin, S.; Burgard, C. D.; Burghgrave, B.; Burke, S.; Burmeister, I.; Busato, E.; Büscher, D.; Büscher, V.; Bussey, P.; Butler, J. M.; Butt, A. I.; Buttar, C. M.; Butterworth, J. M.; Butti, P.; Buttinger, W.; Buzatu, A.; Buzykaev, A. R.; Cabrera Urbán, S.; Caforio, D.; Cairo, V. M.; Cakir, O.; Calace, N.; Calafiura, P.; Calandri, A.; Calderini, G.; Calfayan, P.; Caloba, L. P.; Calvet, D.; Calvet, S.; Camacho Toro, R.; Camarda, S.; Camarri, P.; Cameron, D.; Caminal Armadans, R.; Campana, S.; Campanelli, M.; Campoverde, A.; Canale, V.; Canepa, A.; Cano Bret, M.; Cantero, J.; Cantrill, R.; Cao, T.; Capeans Garrido, M. D. M.; Caprini, I.; Caprini, M.; Capua, M.; Caputo, R.; Cardarelli, R.; Cardillo, F.; Carli, T.; Carlino, G.; Carminati, L.; Caron, S.; Carquin, E.; Carrillo-Montoya, G. D.; Carter, J. R.; Carvalho, J.; Casadei, D.; Casado, M. P.; Casolino, M.; Castaneda-Miranda, E.; Castelli, A.; Castillo Gimenez, V.; Castro, N. F.; Catastini, P.; Catinaccio, A.; Catmore, J. R.; Cattai, A.; Caudron, J.; Cavaliere, V.; Cavalli, D.; Cavalli-Sforza, M.; Cavasinni, V.; Ceradini, F.; Cerio, B. C.; Cerny, K.; Cerqueira, A. S.; Cerri, A.; Cerrito, L.; Cerutti, F.; Cerv, M.; Cervelli, A.; Cetin, S. A.; Chafaq, A.; Chakraborty, D.; Chalupkova, I.; Chang, P.; Chapman, J. D.; Charlton, D. G.; Chau, C. C.; Chavez Barajas, C. A.; Cheatham, S.; Chegwidden, A.; Chekanov, S.; Chekulaev, S. V.; Chelkov, G. A.; Chelstowska, M. A.; Chen, C.; Chen, H.; Chen, K.; Chen, L.; Chen, S.; Chen, X.; Chen, Y.; Cheng, H. C.; Cheng, Y.; Cheplakov, A.; Cheremushkina, E.; Cherkaoui El Moursli, R.; Chernyatin, V.; Cheu, E.; Chevalier, L.; Chiarella, V.; Chiarelli, G.; Chiodini, G.; Chisholm, A. S.; Chislett, R. T.; Chitan, A.; Chizhov, M. V.; Choi, K.; Chouridou, S.; Chow, B. K. B.; Christodoulou, V.; Chromek-Burckhart, D.; Chudoba, J.; Chuinard, A. J.; Chwastowski, J. J.; Chytka, L.; Ciapetti, G.; Ciftci, A. K.; Cinca, D.; Cindro, V.; Cioara, I. A.; Ciocio, A.; Cirotto, F.; Citron, Z. H.; Ciubancan, M.; Clark, A.; Clark, B. L.; Clark, P. J.; Clarke, R. N.; Cleland, W.; Clement, C.; Coadou, Y.; Cobal, M.; Coccaro, A.; Cochran, J.; Coffey, L.; Cogan, J. G.; Colasurdo, L.; Cole, B.; Cole, S.; Colijn, A. P.; Collot, J.; Colombo, T.; Compostella, G.; Conde Muiño, P.; Coniavitis, E.; Connell, S. H.; Connelly, I. A.; Consorti, V.; Constantinescu, S.; Conta, C.; Conti, G.; Conventi, F.; Cooke, M.; Cooper, B. D.; Cooper-Sarkar, A. M.; Cornelissen, T.; Corradi, M.; Corriveau, F.; Corso-Radu, A.; Cortes-Gonzalez, A.; Cortiana, G.; Costa, G.; Costa, M. J.; Costanzo, D.; Côté, D.; Cottin, G.; Cowan, G.; Cox, B. E.; Cranmer, K.; Cree, G.; Crépé-Renaudin, S.; Crescioli, F.; Cribbs, W. A.; Crispin Ortuzar, M.; Cristinziani, M.; Croft, V.; Crosetti, G.; Cuhadar Donszelmann, T.; Cummings, J.; Curatolo, M.; Cuthbert, C.; Czirr, H.; Czodrowski, P.; D'Auria, S.; D'Onofrio, M.; Da Cunha Sargedas De Sousa, M. J.; Da Via, C.; Dabrowski, W.; Dafinca, A.; Dai, T.; Dale, O.; Dallaire, F.; Dallapiccola, C.; Dam, M.; Dandoy, J. R.; Dang, N. P.; Daniells, A. C.; Danninger, M.; Dano Hoffmann, M.; Dao, V.; Darbo, G.; Darmora, S.; Dassoulas, J.; Dattagupta, A.; Davey, W.; David, C.; Davidek, T.; Davies, E.; Davies, M.; Davison, P.; Davygora, Y.; Dawe, E.; Dawson, I.; Daya-Ishmukhametova, R. K.; De, K.; de Asmundis, R.; De Benedetti, A.; De Castro, S.; De Cecco, S.; De Groot, N.; de Jong, P.; De la Torre, H.; De Lorenzi, F.; De Pedis, D.; De Salvo, A.; De Sanctis, U.; De Santo, A.; De Vivie De Regie, J. B.; Dearnaley, W. J.; Debbe, R.; Debenedetti, C.; Dedovich, D. V.; Deigaard, I.; Del Peso, J.; Del Prete, T.; Delgove, D.; Deliot, F.; Delitzsch, C. M.; Deliyergiyev, M.; Dell'Acqua, A.; Dell'Asta, L.; Dell'Orso, M.; Della Pietra, M.; della Volpe, D.; Delmastro, M.; Delsart, P. A.; Deluca, C.; DeMarco, D. A.; Demers, S.; Demichev, M.; Demilly, A.; Denisov, S. P.; Derendarz, D.; Derkaoui, J. E.; Derue, F.; Dervan, P.; Desch, K.; Deterre, C.; Deviveiros, P. O.; Dewhurst, A.; Dhaliwal, S.; Di Ciaccio, A.; Di Ciaccio, L.; Di Domenico, A.; Di Donato, C.; Di Girolamo, A.; Di Girolamo, B.; Di Mattia, A.; Di Micco, B.; Di Nardo, R.; Di Simone, A.; Di Sipio, R.; Di Valentino, D.; Diaconu, C.; Diamond, M.; Dias, F. A.; Diaz, M. A.; Diehl, E. B.; Dietrich, J.; Diglio, S.; Dimitrievska, A.; Dingfelder, J.; Dita, P.; Dita, S.; Dittus, F.; Djama, F.; Djobava, T.; Djuvsland, J. I.; do Vale, M. A. B.; Dobos, D.; Dobre, M.; Doglioni, C.; Dohmae, T.; Dolejsi, J.; Dolezal, Z.; Dolgoshein, B. A.; Donadelli, M.; Donati, S.; Dondero, P.; Donini, J.; Dopke, J.; Doria, A.; Dova, M. T.; Doyle, A. T.; Drechsler, E.; Dris, M.; Dubreuil, E.; Duchovni, E.; Duckeck, G.; Ducu, O. A.; Duda, D.; Dudarev, A.; Duflot, L.; Duguid, L.; Dührssen, M.; Dunford, M.; Duran Yildiz, H.; Düren, M.; Durglishvili, A.; Duschinger, D.; Dyndal, M.; Eckardt, C.; Ecker, K. M.; Edgar, R. C.; Edson, W.; Edwards, N. C.; Ehrenfeld, W.; Eifert, T.; Eigen, G.; Einsweiler, K.; Ekelof, T.; El Kacimi, M.; Ellert, M.; Elles, S.; Ellinghaus, F.; Elliot, A. A.; Ellis, N.; Elmsheuser, J.; Elsing, M.; Emeliyanov, D.; Enari, Y.; Endner, O. C.; Endo, M.; Erdmann, J.; Ereditato, A.; Ernis, G.; Ernst, J.; Ernst, M.; Errede, S.; Ertel, E.; Escalier, M.; Esch, H.; Escobar, C.; Esposito, B.; Etienvre, A. I.; Etzion, E.; Evans, H.; Ezhilov, A.; Fabbri, L.; Facini, G.; Fakhrutdinov, R. M.; Falciano, S.; Falla, R. J.; Faltova, J.; Fang, Y.; Fanti, M.; Farbin, A.; Farilla, A.; Farooque, T.; Farrell, S.; Farrington, S. M.; Farthouat, P.; Fassi, F.; Fassnacht, P.; Fassouliotis, D.; Faucci Giannelli, M.; Favareto, A.; Fayard, L.; Federic, P.; Fedin, O. L.; Fedorko, W.; Feigl, S.; Feligioni, L.; Feng, C.; Feng, E. J.; Feng, H.; Fenyuk, A. B.; Feremenga, L.; Fernandez Martinez, P.; Fernandez Perez, S.; Ferrando, J.; Ferrari, A.; Ferrari, P.; Ferrari, R.; Ferreira de Lima, D. E.; Ferrer, A.; Ferrere, D.; Ferretti, C.; Ferretto Parodi, A.; Fiascaris, M.; Fiedler, F.; Filipčič, A.; Filipuzzi, M.; Filthaut, F.; Fincke-Keeler, M.; Finelli, K. D.; Fiolhais, M. C. N.; Fiorini, L.; Firan, A.; Fischer, A.; Fischer, C.; Fischer, J.; Fisher, W. C.; Fitzgerald, E. A.; Flaschel, N.; Fleck, I.; Fleischmann, P.; Fleischmann, S.; Fletcher, G. T.; Fletcher, G.; Fletcher, R. R. M.; Flick, T.; Floderus, A.; Flores Castillo, L. R.; Flowerdew, M. J.; Formica, A.; Forti, A.; Fournier, D.; Fox, H.; Fracchia, S.; Francavilla, P.; Franchini, M.; Francis, D.; Franconi, L.; Franklin, M.; Frate, M.; Fraternali, M.; Freeborn, D.; French, S. T.; Friedrich, F.; Froidevaux, D.; Frost, J. A.; Fukunaga, C.; Fullana Torregrosa, E.; Fulsom, B. G.; Fusayasu, T.; Fuster, J.; Gabaldon, C.; Gabizon, O.; Gabrielli, A.; Gabrielli, A.; Gach, G. P.; Gadatsch, S.; Gadomski, S.; Gagliardi, G.; Gagnon, P.; Galea, C.; Galhardo, B.; Gallas, E. J.; Gallop, B. J.; Gallus, P.; Galster, G.; Gan, K. K.; Gao, J.; Gao, Y.; Gao, Y. S.; Garay Walls, F. M.; Garberson, F.; García, C.; García Navarro, J. E.; Garcia-Sciveres, M.; Gardner, R. W.; Garelli, N.; Garonne, V.; Gatti, C.; Gaudiello, A.; Gaudio, G.; Gaur, B.; Gauthier, L.; Gauzzi, P.; Gavrilenko, I. L.; Gay, C.; Gaycken, G.; Gazis, E. N.; Ge, P.; Gecse, Z.; Gee, C. N. P.; Geich-Gimbel, Ch.; Geisler, M. P.; Gemme, C.; Genest, M. H.; Gentile, S.; George, M.; George, S.; Gerbaudo, D.; Gershon, A.; Ghasemi, S.; Ghazlane, H.; Giacobbe, B.; Giagu, S.; Giangiobbe, V.; Giannetti, P.; Gibbard, B.; Gibson, S. M.; Gilchriese, M.; Gillam, T. P. S.; Gillberg, D.; Gilles, G.; Gingrich, D. M.; Giokaris, N.; Giordani, M. P.; Giorgi, F. M.; Giorgi, F. M.; Giraud, P. F.; Giromini, P.; Giugni, D.; Giuliani, C.; Giulini, M.; Gjelsten, B. K.; Gkaitatzis, S.; Gkialas, I.; Gkougkousis, E. L.; Gladilin, L. K.; Glasman, C.; Glatzer, J.; Glaysher, P. C. F.; Glazov, A.; Goblirsch-Kolb, M.; Goddard, J. 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G.; Zhu, H.; Zhu, J.; Zhu, Y.; Zhuang, X.; Zhukov, K.; Zibell, A.; Zieminska, D.; Zimine, N. I.; Zimmermann, C.; Zimmermann, S.; Zinonos, Z.; Zinser, M.; Ziolkowski, M.; Živković, L.; Zobernig, G.; Zoccoli, A.; zur Nedden, M.; Zurzolo, G.; Zwalinski, L.

2016-05-01

The distribution of particles inside hadronic jets produced in the decay of boosted W and Z bosons can be used to discriminate such jets from the continuum background. Given that a jet has been identified as likely resulting from the hadronic decay of a boosted W or Z boson, this paper presents a technique for further differentiating Z bosons from W bosons. The variables used are jet mass, jet charge, and a b-tagging discriminant. A likelihood tagger is constructed from these variables and tested in the simulation of W'→ WZ for bosons in the transverse momentum range 200 GeV

A new method to distinguish hadronically decaying boosted Z bosons from W bosons using the ATLAS detector

DOE PAGES

Aad, G.; Abbott, B.; Abdallah, J.; ...

2016-04-28

The distribution of particles inside hadronic jets produced in the decay of boosted W and Z bosons can be used to discriminate such jets from the continuum background. Given that a jet has been identified as likely resulting from the hadronic decay of a boosted W or Z boson, this paper presents a technique for further differentiating Z bosons from W bosons. The variables used are jet mass, jet charge, and a b-tagging discriminant. A likelihood tagger is constructed from these variables and tested in the simulation of W' → WZ for bosons in the transverse momentum range 200 GeV 

A new method to distinguish hadronically decaying boosted Z bosons from W bosons using the ATLAS detector.

PubMed

Aad, G; Abbott, B; Abdallah, J; Abdinov, O; Aben, R; Abolins, M; AbouZeid, O S; Abramowicz, H; Abreu, H; Abreu, R; Abulaiti, Y; Acharya, B S; Adamczyk, L; Adams, D L; Adelman, J; Adomeit, S; Adye, T; Affolder, A A; Agatonovic-Jovin, T; Agricola, J; Aguilar-Saavedra, J A; Ahlen, S P; Ahmadov, F; Aielli, G; Akerstedt, H; Åkesson, T P A; Akimov, A V; Alberghi, G L; Albert, J; Albrand, S; Alconada Verzini, M J; Aleksa, M; Aleksandrov, I N; Alexa, C; Alexander, G; Alexopoulos, T; Alhroob, M; Alimonti, G; Alio, L; Alison, J; Alkire, S P; Allbrooke, B M M; Allport, P P; Aloisio, A; Alonso, A; Alonso, F; Alpigiani, C; Altheimer, A; Alvarez Gonzalez, B; Álvarez Piqueras, D; Alviggi, M G; Amadio, B T; Amako, K; Amaral Coutinho, Y; Amelung, C; Amidei, D; Amor Dos Santos, S P; Amorim, A; Amoroso, S; Amram, N; Amundsen, G; Anastopoulos, C; Ancu, L S; Andari, N; Andeen, T; Anders, C F; Anders, G; Anders, J K; Anderson, K J; Andreazza, A; Andrei, V; Angelidakis, S; Angelozzi, I; Anger, P; Angerami, A; 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Vranjes, N; Vranjes Milosavljevic, M; Vrba, V; Vreeswijk, M; Vuillermet, R; Vukotic, I; Vykydal, Z; Wagner, P; Wagner, W; Wahlberg, H; Wahrmund, S; Wakabayashi, J; Walder, J; Walker, R; Walkowiak, W; Wang, C; Wang, F; Wang, H; Wang, H; Wang, J; Wang, J; Wang, K; Wang, R; Wang, S M; Wang, T; Wang, T; Wang, X; Wanotayaroj, C; Warburton, A; Ward, C P; Wardrope, D R; Washbrook, A; Wasicki, C; Watkins, P M; Watson, A T; Watson, I J; Watson, M F; Watts, G; Watts, S; Waugh, B M; Webb, S; Weber, M S; Weber, S W; Webster, J S; Weidberg, A R; Weinert, B; Weingarten, J; Weiser, C; Weits, H; Wells, P S; Wenaus, T; Wengler, T; Wenig, S; Wermes, N; Werner, M; Werner, P; Wessels, M; Wetter, J; Whalen, K; Wharton, A M; White, A; White, M J; White, R; White, S; Whiteson, D; Wickens, F J; Wiedenmann, W; Wielers, M; Wienemann, P; Wiglesworth, C; Wiik-Fuchs, L A M; Wildauer, A; Wilkens, H G; Williams, H H; Williams, S; Willis, C; Willocq, S; Wilson, A; Wilson, J A; Wingerter-Seez, I; Winklmeier, F; Winter, B T; Wittgen, M; Wittkowski, J; Wollstadt, S J; Wolter, M W; Wolters, H; Wosiek, B K; Wotschack, J; Woudstra, M J; Wozniak, K W; Wu, M; Wu, M; Wu, S L; Wu, X; Wu, Y; Wyatt, T R; Wynne, B M; Xella, S; Xu, D; Xu, L; Yabsley, B; Yacoob, S; Yakabe, R; Yamada, M; Yamaguchi, D; Yamaguchi, Y; Yamamoto, A; Yamamoto, S; Yamanaka, T; Yamauchi, K; Yamazaki, Y; Yan, Z; Yang, H; Yang, H; Yang, Y; Yao, W-M; Yasu, Y; Yatsenko, E; Yau Wong, K H; Ye, J; Ye, S; Yeletskikh, I; Yen, A L; Yildirim, E; Yorita, K; Yoshida, R; Yoshihara, K; Young, C; Young, C J S; Youssef, S; Yu, D R; Yu, J; Yu, J M; Yu, J; Yuan, L; Yuen, S P Y; Yurkewicz, A; Yusuff, I; Zabinski, B; Zaidan, R; Zaitsev, A M; Zalieckas, J; Zaman, A; Zambito, S; Zanello, L; Zanzi, D; Zeitnitz, C; Zeman, M; Zemla, A; Zeng, Q; Zengel, K; Zenin, O; Ženiš, T; Zerwas, D; Zhang, D; Zhang, F; Zhang, H; Zhang, J; Zhang, L; Zhang, R; Zhang, X; Zhang, Z; Zhao, X; Zhao, Y; Zhao, Z; Zhemchugov, A; Zhong, J; Zhou, B; Zhou, C; Zhou, L; Zhou, L; Zhou, M; Zhou, N; Zhu, C G; Zhu, H; Zhu, J; Zhu, Y; Zhuang, X; Zhukov, K; Zibell, A; Zieminska, D; Zimine, N I; Zimmermann, C; Zimmermann, S; Zinonos, Z; Zinser, M; Ziolkowski, M; Živković, L; Zobernig, G; Zoccoli, A; Zur Nedden, M; Zurzolo, G; Zwalinski, L

2016-01-01

The distribution of particles inside hadronic jets produced in the decay of boosted W and Z bosons can be used to discriminate such jets from the continuum background. Given that a jet has been identified as likely resulting from the hadronic decay of a boosted W or Z boson, this paper presents a technique for further differentiating Z bosons from W bosons. The variables used are jet mass, jet charge, and a b -tagging discriminant. A likelihood tagger is constructed from these variables and tested in the simulation of [Formula: see text] for bosons in the transverse momentum range 200 GeV [Formula: see text] 400 GeV in [Formula: see text] TeV pp collisions with the ATLAS detector at the LHC. For Z -boson tagging efficiencies of [Formula: see text], 50, and [Formula: see text], one can achieve [Formula: see text]-boson tagging rejection factors ([Formula: see text]) of 1.7, 8.3 and 1000, respectively. It is not possible to measure these efficiencies in the data due to the lack of a pure sample of high [Formula: see text], hadronically decaying Z bosons. However, the modelling of the tagger inputs for boosted W bosons is studied in data using a [Formula: see text]-enriched sample of events in 20.3 fb[Formula: see text] of data at [Formula: see text] TeV. The inputs are well modelled within uncertainties, which builds confidence in the expected tagger performance.

QCD for Postgraduates (5/5)

ScienceCinema

None

2018-05-14

We will introduce and discuss in some detail the two main classes of jets: cone type and sequential-recombination type. We will discuss their basic properties, as well as more advanced concepts such as jet substructure, jet filtering, ways of optimizing the jet radius, ways of defining the areas of jets, and of establishing the quality measure of the jet-algorithm in terms of discriminating power in specific searches. Finally we will discuss applications for Higgs searches involving boosted particles.

Separator electrode assembly (SEA) with 3-dimensional bioanode and removable air-cathode boosts microbial fuel cell performance

NASA Astrophysics Data System (ADS)

Oliot, M.; Etcheverry, L.; Mosdale, A.; Basseguy, R.; Délia, M.-L.; Bergel, A.

2017-07-01

Separator electrode assemblies (SEAs) were designed by associating a microbial anode with an air-cathode on each side of three different kinds of separator: plastic grid, J-cloth and baking paper. The SEA was designed to allow the air-cathode be removed and replaced without disturbing the bioanode. Power densities up to 6.4 W m-2 were produced by the Grid-SEAs (on average 5.9 ± 0.5 W m-2) while JCloth-SEAs and Paper-SEAs produced 4.8 ± 0.3 and 1.8 ± 0.1 W m-2, respectively. Power densities decreased with time mainly because of fast deterioration of the cathode kinetics. They always increased again when the air-cathodes were replaced by new ones; the Grid-SEAs were thus boosted above 4 W m-2 after 7 weeks of operation. The theoretical analysis of SEA functioning suggested that the high performance of the Grid-SEAs was due to the combination of several virtuous phenomena: the efficient pH balance thanks to free diffusion through the large-mesh grid, the likely mitigation of oxygen crossover thanks to the 3-dimensional structure of the bioanode and the possibility of overcoming cathode fouling by replacing it during MFC operation. Finally, the microbial community of all bioanodes showed stringent selection of Proteiniphilum acetatigenes in proportion with the performance.

Milne boost from Galilean gauge theory

NASA Astrophysics Data System (ADS)

Banerjee, Rabin; Mukherjee, Pradip

2018-03-01

Physical origin of Milne boost invariance of the Newton Cartan spacetime is traced to the effect of local Galilean boosts in its metric structure, using Galilean gauge theory. Specifically, we do not require any gauge field to understand Milne boost invariance.

Optical re-injection in cavity-enhanced absorption spectroscopy

PubMed Central

Leen, J. Brian; O’Keefe, Anthony

2014-01-01

Non-mode-matched cavity-enhanced absorption spectrometry (e.g., cavity ringdown spectroscopy and integrated cavity output spectroscopy) is commonly used for the ultrasensitive detection of trace gases. These techniques are attractive for their simplicity and robustness, but their performance may be limited by the reflection of light from the front mirror and the resulting low optical transmission. Although this low transmitted power can sometimes be overcome with higher power lasers and lower noise detectors (e.g., in the near-infrared), many regimes exist where the available light intensity or photodetector sensitivity limits instrument performance (e.g., in the mid-infrared). In this article, we describe a method of repeatedly re-injecting light reflected off the front mirror of the optical cavity to boost the cavity's circulating power and deliver more light to the photodetector and thus increase the signal-to-noise ratio of the absorption measurement. We model and experimentally demonstrate the method's performance using off-axis cavity ringdown spectroscopy (OA-CRDS) with a broadly tunable external cavity quantum cascade laser. The power coupled through the cavity to the detector is increased by a factor of 22.5. The cavity loss is measured with a precision of 2 × 10−10 cm−1/\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}$\\sqrt {{\\rm Hz;}}$\\end{document} Hz ; an increase of 12 times over the standard off-axis configuration without reinjection and comparable to the best reported sensitivities in the mid-infrared. Finally, the re-injected CRDS system is used to measure the spectrum of several volatile organic compounds, demonstrating the improved ability to resolve weakly absorbing spectroscopic features. PMID:25273701

Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization

PubMed Central

Townsley, Samantha; Mohamed, Zeinab; Guo, Wenjin; McKenna, Jennifer; Cleveland, Brad; LaBranche, Celia; Beaumont, David; Shen, Xiaoying; Yates, Nicole L.; Pinter, Abraham; Tomaras, Georgia D.; Ferrari, Guido; Montefiori, David C.

2016-01-01

ABSTRACT Poxvirus prime-protein boost used in the RV144 trial remains the only immunization strategy shown to elicit a modest level of protection against HIV-1 acquisition in humans. Although neutralizing antibodies (NAb) were generated, they were against sensitive viruses, not the more resistant “tier 2” isolates that dominate circulating strains. Instead, risk reduction correlated with antibodies recognizing epitopes in the V1/V2 region of HIV-1 envelope glycoprotein (Env). Here, we examined whether tier 2 virus NAb and V1/V2-specific non-NAb could be elicited by a poxvirus prime-gp120 boost strategy in a rabbit model. We studied two clade B Envs that differ in multiple parameters, including tissue origin, neutralization sensitivity, and presence of the N197 (N7) glycan that was previously shown to modulate the exposure of conserved epitopes on Env. We demonstrate that immunized rabbits generated cross-reactive neutralizing activities against >50% of the tier 2 global HIV-1 isolates tested. Some of these activities were directed against the CD4 binding site (CD4bs). These rabbits also generated antibodies that recognized protein scaffolds bearing V1/V2 sequences from diverse HIV-1 isolates and mediated antibody-dependent cellular cytotoxicity. However, there are subtle differences in the specificities and the response rates of V1/V2-specific antibodies between animals immunized with different Envs, with or without the N7 glycan. These findings demonstrate that antibody responses that have been correlated with protection against HIV-1 acquisition in humans can be elicited in a preclinical model by a poxvirus prime-gp120 boost strategy and that improvements may be achievable by optimizing the nature of the priming and boosting immunogens. IMPORTANCE The only vaccine approach shown to elicit any protective efficacy against HIV-1 acquisition is based on a poxvirus prime-protein boost regimen (RV144 Thai trial). Reduction of risk was associated with nonneutralizing antibodies targeting the V1/V2 loops of the envelope protein gp120. However, the modest efficacy (31.2%) achieved in this trial highlights the need to examine approaches and factors that may improve vaccine-induced responses, including cross-reactive neutralizing activities. We show here that rabbits immunized with a novel recombinant vaccinia virus prime-gp120 protein boost regimen generated antibodies that recognize protein scaffolds bearing V1/V2 sequences from diverse HIV-1 isolates and mediated antibody-dependent cellular cytotoxicity. Importantly, immunized rabbits also showed neutralizing activities against heterologous tier 2 HIV-1 isolates. These findings may inform the design of prime-boost immunization approaches and help improve the protective efficacy of candidate HIV-1 vaccines. PMID:27440894

Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization.

PubMed

Townsley, Samantha; Mohamed, Zeinab; Guo, Wenjin; McKenna, Jennifer; Cleveland, Brad; LaBranche, Celia; Beaumont, David; Shen, Xiaoying; Yates, Nicole L; Pinter, Abraham; Tomaras, Georgia D; Ferrari, Guido; Montefiori, David C; Hu, Shiu-Lok

2016-10-01

Poxvirus prime-protein boost used in the RV144 trial remains the only immunization strategy shown to elicit a modest level of protection against HIV-1 acquisition in humans. Although neutralizing antibodies (NAb) were generated, they were against sensitive viruses, not the more resistant "tier 2" isolates that dominate circulating strains. Instead, risk reduction correlated with antibodies recognizing epitopes in the V1/V2 region of HIV-1 envelope glycoprotein (Env). Here, we examined whether tier 2 virus NAb and V1/V2-specific non-NAb could be elicited by a poxvirus prime-gp120 boost strategy in a rabbit model. We studied two clade B Envs that differ in multiple parameters, including tissue origin, neutralization sensitivity, and presence of the N197 (N7) glycan that was previously shown to modulate the exposure of conserved epitopes on Env. We demonstrate that immunized rabbits generated cross-reactive neutralizing activities against >50% of the tier 2 global HIV-1 isolates tested. Some of these activities were directed against the CD4 binding site (CD4bs). These rabbits also generated antibodies that recognized protein scaffolds bearing V1/V2 sequences from diverse HIV-1 isolates and mediated antibody-dependent cellular cytotoxicity. However, there are subtle differences in the specificities and the response rates of V1/V2-specific antibodies between animals immunized with different Envs, with or without the N7 glycan. These findings demonstrate that antibody responses that have been correlated with protection against HIV-1 acquisition in humans can be elicited in a preclinical model by a poxvirus prime-gp120 boost strategy and that improvements may be achievable by optimizing the nature of the priming and boosting immunogens. The only vaccine approach shown to elicit any protective efficacy against HIV-1 acquisition is based on a poxvirus prime-protein boost regimen (RV144 Thai trial). Reduction of risk was associated with nonneutralizing antibodies targeting the V1/V2 loops of the envelope protein gp120. However, the modest efficacy (31.2%) achieved in this trial highlights the need to examine approaches and factors that may improve vaccine-induced responses, including cross-reactive neutralizing activities. We show here that rabbits immunized with a novel recombinant vaccinia virus prime-gp120 protein boost regimen generated antibodies that recognize protein scaffolds bearing V1/V2 sequences from diverse HIV-1 isolates and mediated antibody-dependent cellular cytotoxicity. Importantly, immunized rabbits also showed neutralizing activities against heterologous tier 2 HIV-1 isolates. These findings may inform the design of prime-boost immunization approaches and help improve the protective efficacy of candidate HIV-1 vaccines. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

55-mW, 1.2-V, 12-bit, 100-MSPS Pipeline ADCs for Wireless Receivers

NASA Astrophysics Data System (ADS)

Ito, Tomohiko; Kurose, Daisuke; Ueno, Takeshi; Yamaji, Takafumi; Itakura, Tetsuro

For wireless receivers, low-power 1.2-V 12-bit 100-MSPS pipeline ADCs are fabricated in 90-nm CMOS technology. To achieve low-power dissipation at 1.2V without the degradation of SNR, the configuration of 2.5bit/stage is employed with an I/Q amplifier sharing technique. Furthermore, single-stage pseudo-differential amplifiers are used in a Sample-and-Hold (S/H) circuit and a 1st Multiplying Digital-to-Analog Converter (MDAC). The pseudo-differential amplifier with two-gain-stage transimpedance gain-boosting amplifiers realizes high DC gain of more than 90dB with low power. The measured SNR of the 100-MSPS ADC is 66.7dB at 1.2-V supply. Under that condition, each ADC dissipates only 55mW.

Systems analysis of a low-acceleration research facility

NASA Technical Reports Server (NTRS)

Martin, Gary L.; Ferebee, Melvin J., Jr.; Wright, Robert L.

1988-01-01

The Low-Acceleration Research Facility (LARF), an unmanned free-flier that is boosted from low-earth orbit to a desired altitude using an orbital transfer vehicle is discussed. Design techniques used to minimize acceleration-causing disturbances and to create an ultra-quiet workshop are discussed, focusing on residual acceleration induced by the environment, the spacecraft and experiments. The selection and integration of critical subsystems, such as electrical power and thermal control, that enable the LARf to accomodate sub-microgravity levels for extended periods of time are presented, including a discussion of the Low-Acceleration Module, which will supply the payload with 25.0 kW of power, and up to 11.8 kW in the low-power mode. Also, the data management, communications, guidance, navigation and control, and structural features of supporting subsystems are examined.

Low-frequency wideband vibration energy harvesting by using frequency up-conversion and quin-stable nonlinearity

NASA Astrophysics Data System (ADS)

Wang, Chen; Zhang, Qichang; Wang, Wei

2017-07-01

This work presents models and experiments of an impact-driven and frequency up-converted wideband piezoelectric-based vibration energy harvester with a quintuple-well potential induced by the combination effect of magnetic nonlinearity and mechanical piecewise-linearity. Analysis shows that the interwell motions during coupled vibration period enable to increase electrical power output in comparison to conventional frequency up-conversion technology. Besides, the quintuple-well potential with shallower potential wells could extend the harvester's operating bandwidth to lower frequencies. Experiments demonstrate our proposed approach can dramatically boost the measured power of the energy harvester as much as 35 times while its lower cut-off frequency is two times lower than that of a conventional counterpart. These results reveal our proposed approach shows promise for powering portable wireless smart devices from low-intensity, low-frequency vibration sources.

DOD and Navy applications for laser power beaming

NASA Astrophysics Data System (ADS)

Bennett, Harold E.

1995-04-01

Satellites are of vital importance to the Department of Defense and the Navy as well as to the civilian economy. For example, about 90% of the communications to the fleet are by satellite. Economical means for putting satellites into orbit and maintaining and extending their lifetimes in orbit are just as important for the military as for civilian industries. There is also a significant economic impact to the ability to repair rather than replace satellites that are malfunctioning or have been inserted into the wrong orbits. Laser power beaming can not only accomplish these tasks but also promises to move satellites in orbit quickly and inexpensively, provide boost power for degraded satellites or those which suffer intentional jamming from adversaries, remove space junk even in geosynchronous orbit and provide very high resolution pictures of objects in space by eliminating atmospheric disturbances.

Heterologous Prime-Boost Immunisation Regimens Against Infectious Diseases

DTIC Science & Technology

2006-08-01

of these cells by boosting. DNA vaccines are good priming agents since they are internalised by antigen presenting cells and can induce antigen...presentation via both MHC class I and class II, thereby inducing both cytotoxic T lymphocytes and type 1-helper T lymphocytes. Successful boosting agents ...assessing prime-boost vaccine combinations for protection against infectious agents . • In a number of prime - boost studies, the inclusion of growth

Electric Vehicle Battery Development Gains Momentum - Continuum Magazine

Science.gov Websites

to improve and accelerate battery design and boost EDV performance and consumer appeal - and chemistry, cell design, and battery pack options for particular vehicle platforms Factor in electrochemical separate, competitive, validated, and easy-to-use CAEBAT software tools for battery pack design. The three

Semantic Boost on Episodic Associations: An Empirically-Based Computational Model

ERIC Educational Resources Information Center

Silberman, Yaron; Bentin, Shlomo; Miikkulainen, Risto

2007-01-01

Words become associated following repeated co-occurrence episodes. This process might be further determined by the semantic characteristics of the words. The present study focused on how semantic and episodic factors interact in incidental formation of word associations. First, we found that human participants associate semantically related words…

Champions: District Leaders Build Skills to Boost Educator Practice

ERIC Educational Resources Information Center

Psencik, Kay; Brown, Frederick; Cain, Laura; Coleman, Ramona; Cummings, C. Todd

2014-01-01

Fort Wayne Community Schools continue to increase student learning and meet state and national standards and expectations annually based on several factors that have made a difference for educators within the system: district and principal leadership, learning teams, effective learning designs, and deep commitment to a culture of learning. Fort…

How Much Can We Boost IQ and Scholastic Achievement?

ERIC Educational Resources Information Center

Jensen, Arthur R.

The importance and consequences of raising the average ability level (IQ) of the population requires consideration of the ability level that society requires, how the relevant abilities are distributed, and the efficiency of the current educational process. Within the framework of these factors, the document discusses the determinants of mental…

Boosted ARTMAP: modifications to fuzzy ARTMAP motivated by boosting theory.

PubMed

Verzi, Stephen J; Heileman, Gregory L; Georgiopoulos, Michael

2006-05-01

In this paper, several modifications to the Fuzzy ARTMAP neural network architecture are proposed for conducting classification in complex, possibly noisy, environments. The goal of these modifications is to improve upon the generalization performance of Fuzzy ART-based neural networks, such as Fuzzy ARTMAP, in these situations. One of the major difficulties of employing Fuzzy ARTMAP on such learning problems involves over-fitting of the training data. Structural risk minimization is a machine-learning framework that addresses the issue of over-fitting by providing a backbone for analysis as well as an impetus for the design of better learning algorithms. The theory of structural risk minimization reveals a trade-off between training error and classifier complexity in reducing generalization error, which will be exploited in the learning algorithms proposed in this paper. Boosted ART extends Fuzzy ART by allowing the spatial extent of each cluster formed to be adjusted independently. Boosted ARTMAP generalizes upon Fuzzy ARTMAP by allowing non-zero training error in an effort to reduce the hypothesis complexity and hence improve overall generalization performance. Although Boosted ARTMAP is strictly speaking not a boosting algorithm, the changes it encompasses were motivated by the goals that one strives to achieve when employing boosting. Boosted ARTMAP is an on-line learner, it does not require excessive parameter tuning to operate, and it reduces precisely to Fuzzy ARTMAP for particular parameter values. Another architecture described in this paper is Structural Boosted ARTMAP, which uses both Boosted ART and Boosted ARTMAP to perform structural risk minimization learning. Structural Boosted ARTMAP will allow comparison of the capabilities of off-line versus on-line learning as well as empirical risk minimization versus structural risk minimization using Fuzzy ARTMAP-based neural network architectures. Both empirical and theoretical results are presented to enhance the understanding of these architectures.

Local digital control of power electronic converters in a dc microgrid based on a-priori derivation of switching surfaces

NASA Astrophysics Data System (ADS)

Banerjee, Bibaswan

In power electronic basedmicrogrids, the computational requirements needed to implement an optimized online control strategy can be prohibitive. The work presented in this dissertation proposes a generalized method of derivation of geometric manifolds in a dc microgrid that is based on the a-priori computation of the optimal reactions and trajectories for classes of events in a dc microgrid. The proposed states are the stored energies in all the energy storage elements of the dc microgrid and power flowing into them. It is anticipated that calculating a large enough set of dissimilar transient scenarios will also span many scenarios not specifically used to develop the surface. These geometric manifolds will then be used as reference surfaces in any type of controller, such as a sliding mode hysteretic controller. The presence of switched power converters in microgrids involve different control actions for different system events. The control of the switch states of the converters is essential for steady state and transient operations. A digital memory look-up based controller that uses a hysteretic sliding mode control strategy is an effective technique to generate the proper switch states for the converters. An example dcmicrogrid with three dc-dc boost converters and resistive loads is considered for this work. The geometric manifolds are successfully generated for transient events, such as step changes in the loads and the sources. The surfaces corresponding to a specific case of step change in the loads are then used as reference surfaces in an EEPROM for experimentally validating the control strategy. The required switch states corresponding to this specific transient scenario are programmed in the EEPROM as a memory table. This controls the switching of the dc-dc boost converters and drives the system states to the reference manifold. In this work, it is shown that this strategy effectively controls the system for a transient condition such as step changes in the loads for the example case.

HIV-1 gp120 and Modified Vaccinia Virus Ankara (MVA) gp140 Boost Immunogens Increase Immunogenicity of a DNA/MVA HIV-1 Vaccine.

PubMed

Shen, Xiaoying; Basu, Rahul; Sawant, Sheetal; Beaumont, David; Kwa, Sue Fen; LaBranche, Celia; Seaton, Kelly E; Yates, Nicole L; Montefiori, David C; Ferrari, Guido; Wyatt, Linda S; Moss, Bernard; Alam, S Munir; Haynes, Barton F; Tomaras, Georgia D; Robinson, Harriet L

2017-12-15

An important goal of human immunodeficiency virus (HIV) vaccine design is identification of strategies that elicit effective antiviral humoral immunity. One novel approach comprises priming with DNA and boosting with modified vaccinia virus Ankara (MVA) expressing HIV-1 Env on virus-like particles. In this study, we evaluated whether the addition of a gp120 protein in alum or MVA-expressed secreted gp140 (MVAgp140) could improve immunogenicity of a DNA prime-MVA boost vaccine. Five rhesus macaques per group received two DNA primes at weeks 0 and 8 followed by three MVA boosts (with or without additional protein or MVAgp140) at weeks 18, 26, and 40. Both boost immunogens enhanced the breadth of HIV-1 gp120 and V1V2 responses, antibody-dependent cellular cytotoxicity (ADCC), and low-titer tier 1B and tier 2 neutralizing antibody responses. However, there were differences in antibody kinetics, linear epitope specificity, and CD4 T cell responses between the groups. The gp120 protein boost elicited earlier and higher peak responses, whereas the MVAgp140 boost resulted in improved antibody durability and comparable peak responses after the final immunization. Linear V3 specific IgG responses were particularly enhanced by the gp120 boost, whereas the MVAgp140 boost also enhanced responses to linear C5 and C2.2 epitopes. Interestingly, gp120, but not the MVAgp140 boost, increased peak CD4 + T cell responses. Thus, both gp120 and MVAgp140 can augment potential protection of a DNA/MVA vaccine by enhancing gp120 and V1/V2 antibody responses, whereas potential protection by gp120, but not MVAgp140 boosts, may be further impacted by increased CD4 + T cell responses. IMPORTANCE Prior immune correlate analyses with humans and nonhuman primates revealed the importance of antibody responses in preventing HIV-1 infection. A DNA prime-modified vaccinia virus Ankara (MVA) boost vaccine has proven to be potent in eliciting antibody responses. Here we explore the ability of boosts with recombinant gp120 protein or MVA-expressed gp140 to enhance antibody responses elicited by the GOVX-B11 DNA prime-MVA boost vaccine. We found that both types of immunogen boosts enhanced potentially protective antibody responses, whereas the gp120 protein boosts also increased CD4 + T cell responses. Our data provide important information for HIV vaccine designs that aim for effective and balanced humoral and T cell responses. Copyright © 2017 Shen et al.

Variable Thrust, Multiple Start Hybrid Motor Solutions for Missile and Space Applications

DTIC Science & Technology

2010-06-01

considered: I. Boost/Sustain/Boost. Simulating a tactical solid rocket motor profile with another boost at the end to demonstrate a "throttle up", this...of tactical solid rocket motors were tested with 75%, 50%, and lower sustain-to- boost chamber pressure ratios with rapid throttle-up achieved... solid rocket motors were tested with 75%, 50%, and lower sustain-to-boost chamber pressure ratios with rapid throttle-up achieved following the sustain

Do review articles boost journal impact factors? A longitudinal analysis for five pharmacology journals.

PubMed

Amiri, Marjan; Michel, Martin C

2018-06-21

The impact factor is a frequently applied tool in research output analytics. Based on five consecutive publication years each of five pharmacology journals, we have analyzed to which extent review articles yield more impact factor-relevant citations than original articles. Our analysis shows that review articles are quoted about twice as often as original articles published in the same year in the same journal. We conclude that inclusion of review articles does not substantially affect the impact factor of a journal unless they account for considerably more than 10% of all published articles.

Assessment of land use factors associated with dengue cases in Malaysia using Boosted Regression Trees.

PubMed

Cheong, Yoon Ling; Leitão, Pedro J; Lakes, Tobia

2014-07-01

The transmission of dengue disease is influenced by complex interactions among vector, host and virus. Land use such as water bodies or certain agricultural practices have been identified as likely risk factors for dengue because of the provision of suitable habitats for the vector. Many studies have focused on the land use factors of dengue vector abundance in small areas but have not yet studied the relationship between land use factors and dengue cases for large regions. This study aims to clarify if land use factors other than human settlements, e.g. different types of agricultural land use, water bodies and forest are associated with reported dengue cases from 2008 to 2010 in the state of Selangor, Malaysia. From the correlative relationship, we aim to generate a prediction risk map. We used Boosted Regression Trees (BRT) to account for nonlinearities and interactions between the factors with high predictive accuracies. Our model with a cross-validated performance score (Area Under the Receiver Operator Characteristic Curve, ROC AUC) of 0.81 showed that the most important land use factors are human settlements (model importance of 39.2%), followed by water bodies (16.1%), mixed horticulture (8.7%), open land (7.5%) and neglected grassland (6.7%). A risk map after 100 model runs with a cross-validated ROC AUC mean of 0.81 (±0.001 s.d.) is presented. Our findings may be an important asset for improving surveillance and control interventions for dengue. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

How Social Communications Influence Advertising Perception and Response in Online Communities?

PubMed Central

Zeng, Fue; Tao, Ran; Yang, Yanwu; Xie, Tingting

2017-01-01

This research aims to explore how social communications of online communities affect users’ perception and responses toward social media advertising. We developed a conceptual model based on the SBT, encapsulating 9 constructs and 10 hypothesis extracted from the extant social media advertising literature. Our research outcome proves that social communications can effectively boost users’ behaviors to be in accordance with an online social community, thus facilitate their acceptance and responses toward social media advertising, with users’ group intention as an intervening factor. From an operational standpoint, it’s an effective way to build and maintain social bonds between users and the community by boosting social communications, supporting fluent interpersonal communications. In addition, managers of an online community should elaborate on users’ group intentions to increase users’ advertising acceptance and response. PMID:28855879

How Social Communications Influence Advertising Perception and Response in Online Communities?

PubMed

Zeng, Fue; Tao, Ran; Yang, Yanwu; Xie, Tingting

2017-01-01

This research aims to explore how social communications of online communities affect users' perception and responses toward social media advertising. We developed a conceptual model based on the SBT, encapsulating 9 constructs and 10 hypothesis extracted from the extant social media advertising literature. Our research outcome proves that social communications can effectively boost users' behaviors to be in accordance with an online social community, thus facilitate their acceptance and responses toward social media advertising, with users' group intention as an intervening factor. From an operational standpoint, it's an effective way to build and maintain social bonds between users and the community by boosting social communications, supporting fluent interpersonal communications. In addition, managers of an online community should elaborate on users' group intentions to increase users' advertising acceptance and response.

KSC-2015-1364

NASA Image and Video Library

2015-02-11

NOAA’s Deep Space Climate Observatory spacecraft, or DSCOVR, gets a boost into space aboard the SpaceX Falcon 9 rocket. Liftoff from Space Launch Complex 40 at Cape Canaveral Air Force Station in Florida occurred at 6:03 p.m. EST. DSCOVR is a partnership between NOAA, NASA and the U.S. Air Force, and will maintain the nation's real-time solar wind monitoring capabilities. To learn more about DSCOVR, visit http://www.nesdis.noaa.gov/DSCOVR. Photo credit: NASA/Tony Gray and Tim Powers

KSC-2015-1358

NASA Image and Video Library

2015-02-11

NOAA’s Deep Space Climate Observatory spacecraft, or DSCOVR, is boosted into space aboard the SpaceX Falcon 9 rocket. Liftoff from Space Launch Complex 40 at Cape Canaveral Air Force Station in Florida occurred at 6:03 p.m. EST. DSCOVR is a partnership between NOAA, NASA and the U.S. Air Force, and will maintain the nation's real-time solar wind monitoring capabilities. To learn more about DSCOVR, visit http://www.nesdis.noaa.gov/DSCOVR. Photo credit: NASA/Tony Gray and Tim Powers

The Air Campaign vs. Ballistic Missiles: Seeking the Strategic Win in the 21st Century

DTIC Science & Technology

2017-06-01

Bombing to Win: Air Power and Coercion in War (Ithaca, NY: Cornell University Press, 1996), 7. 3 Edward B. Westermann, “The Limits of Soviet Airpower...decisive effect on London and its decision makers, 2) retaliate against the British night bombing of German cities, and 3) boost the German people’s morale...History Interview of Reichminister Albert Speer Interview No. 11, 22 May 1945, Call # 137.315-11, IRIS # 00113506, United States Strategic Bombing

A-10 Thunderbolt II (Warthog) Systems Engineering Case Study

DTIC Science & Technology

2010-01-01

Visual Flight Rules (VFR) navigation aids. The “lean” package added Doppler Navigation for night and adverse weather, and a radar ranger and gun...and a big boost for the technology came in 1965 when the Air Force selected the TF39 engine to power the C-5 Galaxy heavy lift aircraft. Still, there...and Staff College, entitled to wear the Ranger Tab and has a real appreciation for the role of CAS in combat. Upon leaving active duty he served

External validation of the bilirubin-atazanavir nomogram for assessment of atazanavir plasma exposure in HIV-1-infected patients.

PubMed

Rekić, Dinko; Röshammar, Daniel; Bergstrand, Martin; Tarning, Joel; Calcagno, Andrea; D'Avolio, Antonio; Ormaasen, Vidar; Vigan, Marie; Barrail-Tran, Aurélie; Ashton, Michael; Gisslén, Magnus; Äbelö, Angela

2013-04-01

Atazanavir increases plasma bilirubin levels in a concentration-dependent manner. Due to less costly and readily available assays, bilirubin has been proposed as a marker of atazanavir exposure. In this work, a previously developed nomogram for detection of suboptimal atazanavir exposure is validated against external patient populations. The bilirubin nomogram was validated against 311 matching bilirubin and atazanavir samples from 166 HIV-1-infected Norwegian, French, and Italian patients on a ritonavir-boosted regimen. In addition, the nomogram was evaluated in 56 Italian patients on an unboosted regimen. The predictive properties of the nomogram were validated against observed atazanavir plasma concentrations. The use of the nomogram to detect non-adherence was also investigated by simulation. The bilirubin nomogram predicted suboptimal exposure in the patient populations on a ritonavir-boosted regimen with a negative predictive value of 97% (95% CI 95-100). The bilirubin nomogram and monitoring of atazanavir concentrations had similar predictive properties for detecting non-adherence based on simulations. Although both methods performed adequately during a period of non-adherence, they had lower predictive power to detect past non-adherence episodes. Using the bilirubin nomogram for detection of suboptimal atazanavir exposure in patients on a ritonavir-boosted regimen is a rapid and cost-effective alternative to routine measurements of the actual atazanavir exposure in plasma. Its application may be useful in clinical settings if atazanavir concentrations are not available.

Boosted structured additive regression for Escherichia coli fed-batch fermentation modeling.

PubMed

Melcher, Michael; Scharl, Theresa; Luchner, Markus; Striedner, Gerald; Leisch, Friedrich

2017-02-01

The quality of biopharmaceuticals and patients' safety are of highest priority and there are tremendous efforts to replace empirical production process designs by knowledge-based approaches. Main challenge in this context is that real-time access to process variables related to product quality and quantity is severely limited. To date comprehensive on- and offline monitoring platforms are used to generate process data sets that allow for development of mechanistic and/or data driven models for real-time prediction of these important quantities. Ultimate goal is to implement model based feed-back control loops that facilitate online control of product quality. In this contribution, we explore structured additive regression (STAR) models in combination with boosting as a variable selection tool for modeling the cell dry mass, product concentration, and optical density on the basis of online available process variables and two-dimensional fluorescence spectroscopic data. STAR models are powerful extensions of linear models allowing for inclusion of smooth effects or interactions between predictors. Boosting constructs the final model in a stepwise manner and provides a variable importance measure via predictor selection frequencies. Our results show that the cell dry mass can be modeled with a relative error of about ±3%, the optical density with ±6%, the soluble protein with ±16%, and the insoluble product with an accuracy of ±12%. Biotechnol. Bioeng. 2017;114: 321-334. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Pan-Influenza A Protection by Prime-Boost Vaccination with Cold-Adapted Live-Attenuated Influenza Vaccine in a Mouse Model.

PubMed

Jang, Yo Han; Kim, Joo Young; Byun, Young Ho; Son, Ahyun; Lee, Jeong-Yoon; Lee, Yoon Jae; Chang, Jun; Seong, Baik Lin

2018-01-01

Influenza virus infections continually pose a major public health threat with seasonal epidemics and sporadic pandemics worldwide. While currently licensed influenza vaccines provide only strain-specific protection, antigenic drift and shift occasionally render the viruses resistant to the host immune responses, which highlight the need for a vaccine that provides broad protection against multiple subtypes. In this study, we suggest a vaccination strategy using cold-adapted, live attenuated influenza vaccines (CAIVs) to provide a broad, potent, and safe cross-protection covering antigenically distinct hemagglutinin (HA) groups 1 and 2 influenza viruses. Using a mouse model, we tested different prime-boost combinations of CAIVs for their ability to induce humoral and T-cell responses, and protective efficacy against H1 and H5 (HA group 1) as well as H3 and H7 (HA group 2) influenza viruses. Notably, even in the absence of antibody-mediated neutralizing activity or HA inhibitory activity in vitro , CAIVs provided a potent protection against heterologous and heterosubtypic lethal challenges in vivo . Heterologous combination of prime (H1)-boost (H5) vaccine strains showed the most potent cross-protection efficacy. In vivo depletion experiments demonstrated not only that T cells and natural killer cells contributed to the cross-protection, but also the involvement of antibody-dependent mechanisms for the cross-protection. Vaccination-induced antibodies did not enhance the infectivity of heterologous viruses, and prime vaccination did not interfere with neutralizing antibody generation by the boost vaccination, allaying vaccine safety concerns associated with heterogeneity between the vaccines and challenge strains. Our data show that CAIV-based strategy can serve as a simple but powerful option for developing a "truly" universal influenza vaccine providing pan-influenza A protection, which has not been achieved yet by other vaccine strategies. The promising results of potency, breadth, and safety demonstrated in the mouse model support further studies in higher animal models for clinical relevance.

Pan-Influenza A Protection by Prime–Boost Vaccination with Cold-Adapted Live-Attenuated Influenza Vaccine in a Mouse Model

PubMed Central

Jang, Yo Han; Kim, Joo Young; Byun, Young Ho; Son, Ahyun; Lee, Jeong-Yoon; Lee, Yoon Jae; Chang, Jun; Seong, Baik Lin

2018-01-01

Influenza virus infections continually pose a major public health threat with seasonal epidemics and sporadic pandemics worldwide. While currently licensed influenza vaccines provide only strain-specific protection, antigenic drift and shift occasionally render the viruses resistant to the host immune responses, which highlight the need for a vaccine that provides broad protection against multiple subtypes. In this study, we suggest a vaccination strategy using cold-adapted, live attenuated influenza vaccines (CAIVs) to provide a broad, potent, and safe cross-protection covering antigenically distinct hemagglutinin (HA) groups 1 and 2 influenza viruses. Using a mouse model, we tested different prime–boost combinations of CAIVs for their ability to induce humoral and T-cell responses, and protective efficacy against H1 and H5 (HA group 1) as well as H3 and H7 (HA group 2) influenza viruses. Notably, even in the absence of antibody-mediated neutralizing activity or HA inhibitory activity in vitro, CAIVs provided a potent protection against heterologous and heterosubtypic lethal challenges in vivo. Heterologous combination of prime (H1)–boost (H5) vaccine strains showed the most potent cross-protection efficacy. In vivo depletion experiments demonstrated not only that T cells and natural killer cells contributed to the cross-protection, but also the involvement of antibody-dependent mechanisms for the cross-protection. Vaccination-induced antibodies did not enhance the infectivity of heterologous viruses, and prime vaccination did not interfere with neutralizing antibody generation by the boost vaccination, allaying vaccine safety concerns associated with heterogeneity between the vaccines and challenge strains. Our data show that CAIV-based strategy can serve as a simple but powerful option for developing a “truly” universal influenza vaccine providing pan-influenza A protection, which has not been achieved yet by other vaccine strategies. The promising results of potency, breadth, and safety demonstrated in the mouse model support further studies in higher animal models for clinical relevance. PMID:29449842

Magnetically coupled resonance wireless charging technology principles and transfer mechanisms

NASA Astrophysics Data System (ADS)

Zhou, Jiehua; Wan, Jian; Ma, Yinping

2017-05-01

With the tenure of Electric-Vehicle rising around the world, the charging methods have been paid more and more attention, the current charging mode mainly has the charging posts and battery swapping station. The construction of the charging pile or battery swapping station not only require lots of manpower, material costs but the bare conductor is also easy to generate electric spark hidden safety problems, still occupies large space. Compared with the wired charging, wireless charging mode is flexible, unlimited space and location factors and charging for vehicle safety and quickly. It complements the traditional charging methods in adaptability and the independent charge deficiencies. So the researching the wireless charging system have an important practical significance and application value. In this paper, wireless charging system designed is divided into three parts: the primary side, secondary side and resonant coupling. The main function of the primary side is to generate high-frequency alternating current, so selecting CLASS-E amplifier inverter structure through the research on full bridge, half-bridge and power amplification circuit. Addition, the wireless charging system is susceptible to outside interference, frequency drift phenomenon. Combined with the wireless energy transmission characteristics, resonant parts adopt resonant coupling energy transmission scheme and the Series-Series coupling compensation structure. For the electric vehicle charging power and voltage requirements, the main circuit is a full bridge inverter and Boost circuit used as the secondary side.

Diversity of fuel sources for electricity generation in an evolving U.S. power sector

NASA Astrophysics Data System (ADS)

DiLuccia, Janelle G.

Policymakers increasingly have shown interest in options to boost the relative share of renewable or clean electricity generating sources in order to reduce negative environmental externalities from fossil fuels, guard against possible resource constraints, and capture economic advantages from developing new technologies and industries. Electric utilities and non-utility generators make decisions regarding their generation mix based on a number of different factors that may or may not align with societal goals. This paper examines the makeup of the electric power sector to determine how the type of generator and the presence (or lack) of competition in electricity markets at the state level may relate to the types of fuel sources used for generation. Using state-level electricity generation data from the U.S. Energy Information Administration from 1990 through 2010, this paper employs state and time fixed-effects regression modeling to attempt to isolate the impacts of state-level restructuring policies and the emergence of non-utility generators on states' generation from coal, from fossil fuel and from renewable sources. While the analysis has significant limitations, I do find that state-level electricity restructuring has a small but significant association with lowering electricity generation from coal specifically and fossil fuels more generally. Further research into the relationship between competition and fuel sources would aid policymakers considering legislative options to influence the generation mix.

Study of the gamma-ray spectrum from the Galactic Center in view of multi-TeV dark matter candidates

NASA Astrophysics Data System (ADS)

Belikov, Alexander V.; Zaharijas, Gabrijela; Silk, Joseph

2012-10-01

Motivated by the complex gamma-ray spectrum of the Galactic Center source now measured over five decades in energy, we revisit the issue of the role of dark matter (DM) annihilations in this interesting region. We reassess whether the emission measured by the HESS collaboration could be a signature of dark matter annihilation, and we use the Fermi LAT spectrum to model the emission from SgrA*, using power-law spectral fits. We find that good fits are achieved by a power law with an index ˜2.5-2.6, in combination with a spectrum similar to the one observed from pulsar population and with a spectrum from a ≳10TeV DM annihilating to a mixture of bb¯ and harder τ+τ- channels and with boost factors of the order of a hundred. Alternatively, we also consider the combination of a log-parabola fit with the DM contribution. Finally, as both the spectrum of gamma rays from the Galactic Center and the spectrum of cosmic ray electrons exhibit a cutoff at TeV energies, we study the dark matter fits to both data sets. Constraining the spectral shape of the purported dark matter signal provides a robust way of comparing data. We find a marginal overlap only between the 99.999% C.L. regions in parameter space.