Solar photovoltaic reflective trough collection structure

DOEpatents

Anderson, Benjamin J.; Sweatt, William C.; Okandan, Murat; Nielson, Gregory N.

2015-11-19

A photovoltaic (PV) solar concentration structure having at least two troughs encapsulated in a rectangular parallelepiped optical plastic structure, with the troughs filled with an optical plastic material, the troughs each having a reflective internal surface and approximately parabolic geometry, and the troughs each including photovoltaic cells situated so that light impinging on the optical plastic material will be concentrated onto the photovoltaic cells. Multiple structures can be connected to provide a solar photovoltaic collection system that provides portable, efficient, low-cost electrical power.

A review of Andasol 3 and perspective for parabolic trough CSP plants in South Africa

NASA Astrophysics Data System (ADS)

Dinter, Frank; Möller, Lucas

2016-05-01

Andasol 3 is a 50 MW parabolic trough concentrating solar power plant with thermal energy storage in Andalusia, southern Spain. Having started operating in 2011 as one of the first plants of its kind in Spain it has been followed by more than 50 in the country since. For the reason that CSP plants with storage have the potential to compete against fossil fuel fired plants much better than any other renewable energy source a long-term review of such a plant operating on a commercial scale is needed. With data at hand documenting Andasol 3's operation over the course of one year between July 2013 and June 2014 we intend to provide such a review. We calculated the plants overall efficiency, its capacity factor, the gross energy generation as well as auxiliary powers on a monthly basis to reflect upon its overall performance. It was also looked at the benefits caused by the thermal energy storage and especially how steadily and reliably the plant was able to operate. With basic background information about physical, geographical and meteorological aspects influencing the solar resource, its variation and a CSP plant's performance a qualitative estimation for a parabolic trough plant located in South Africa was made.

Coolidge solar powered irrigation pumping project

NASA Technical Reports Server (NTRS)

Larson, D. L.

1980-01-01

A 150 kW solar thermal electric power plant which includes over 2100 square meters of parabolic trough type collectors and an organic Rankine cycle turbine engine was constructed on an irrigated farm. The plant is interconnected with the electrical utility grid. Operation is providing an evaluation of equipment performance and operating and maintenance requirements as well as the desirability of an on farm location.

OUT Success Stories: Solar Trough Power Plants

DOE R&D Accomplishments Database

Jones, J.

2000-08-01

The Solar Electric Generating System (SEGS) plants use parabolic-trough solar collectors to capture the sun's energy and convert it to heat. The SEGS plants range in capacity from 13.8 to 80 MW, and they were constructed to meet Southern California Edison Company's periods of peak power demand.

Energy 101: Concentrating Solar Power

ScienceCinema

None

2018-02-07

From towers to dishes to linear mirrors to troughs, concentrating solar power (CSP) technologies reflect and collect solar heat to generate electricity. A single CSP plant can generate enough power for about 90,000 homes. This video explains what CSP is, how it works, and how systems like parabolic troughs produce renewable power. For more information on the Office of Energy Efficiency and Renewable Energy's CSP research, see the Solar Energy Technology Program's Concentrating Solar Power Web page at http://www1.eere.energy.gov/solar/csp_program.html.

Concentrating Solar Power Projects - Delingha 50MW Thermal Oil Parabolic

Science.gov Websites

Trough project | Concentrating Solar Power | NREL Delingha 50MW Thermal Oil Parabolic Trough project Status Date: April 17, 2017 Project Overview Project Name: Delingha 50MW Thermal Oil Parabolic Contractor: IDOM : Thermal energy storage system engineering Plant Configuration Solar Field # of Loops: 190

Concentrating Solar Power Projects - Urat Middle Banner 100MW Thermal Oil

Science.gov Websites

Parabolic Trough project | Concentrating Solar Power | NREL Middle Banner 100MW Thermal Oil Thermal Oil Parabolic Trough project Country: China Location: Urat Middle Banner (Inner Mongolia) Owner(s , 2017 Start Production: 2018 Participants Developer(s): Changzhou Royal Tech Solar Thermal Equipment Co

Concentrating Solar Power Projects - Gulang 100MW Thermal Oil Parabolic

Science.gov Websites

Trough project | Concentrating Solar Power | NREL Gulang 100MW Thermal Oil Parabolic Trough project Status Date: September 29, 2016 Project Overview Project Name: Gulang 100MW Thermal Oil Parabolic ): Webmaster Solar Participants Developer(s): Changzhou Royal Tech Solar Thermal Equipment Co., Ltd. Owner(s

Concentrating Solar Power Projects - Parabolic Trough Projects |

Science.gov Websites

Project Godawari Solar Project Gujarat Solar One Gulang 100MW Thermal Oil Parabolic Trough project Guzmán Kuraymat (ISCC Kuraymat) Kathu Solar Park KaXu Solar One KVK Energy Solar Project La Africana La Dehesa La Power Facility Nevada Solar One (NSO) NOOR I NOOR II Olivenza 1 Orellana Palma del Río I Palma del Río

Oblique H.F. radiowave propagation in the main trough region of the ionosphere

NASA Astrophysics Data System (ADS)

Lockwood, M.; Mitchell, V. B.

1980-12-01

The propagation of 7.335 MHz, CW signals over a 5212 km subauroral, west-east path is studied. Measurements and semiempirical predictions are made of the amplitude distributions and Doppler shifts of the received signals. The observed amplitude distribution is fitted with a numerical fading model, yielding the power losses suffered by the signals during propagation via the predominating modes. The mid-latitude trough in the F2 peak ionization density is predicted by a statistical model to be at the latitudes of this path at these times and at low K sub p values; a sharp cut-off in low-power losses at a mean K sub p of 2.75 strongly implicates the trough in the propagation of these signals. It is shown that a simple extension of this model to allow for the trough can reproduce the form of the observed diurnal variation.

Concentrating Solar Power Projects - DEWA CSP Trough Project |

Science.gov Websites

: Parabolic trough Turbine Capacity: Net: 600.0 MW Gross: 600.0 MW Status: Under development Start Year: 2020 Ground: 2018 Start Production: 2020 PPA/Tariff Rate: 7.3 US cents per kWh Participants Developer(s): ACWA

The effects of regional insolation differences upon advanced solar thermal electric power plant performance and energy costs

NASA Technical Reports Server (NTRS)

Latta, A. F.; Bowyer, J. M.; Fujita, T.

1979-01-01

This paper presents the performance and cost of four 10-MWe advanced solar thermal electric power plants sited in various regions of the continental United States. Each region has different insolation characteristics which result in varying collector field areas, plant performance, capital costs, and energy costs. The paraboloidal dish, central receiver, cylindrical parabolic trough, and compound parabolic concentrator (CPC) comprise the advanced concepts studied. This paper contains a discussion of the regional insolation data base, a description of the solar systems' performances and costs, and a presentation of a range for the forecast cost of conventional electricity by region and nationally over the next several decades.

Performance Analysis of XCPC Powered Solar Cooling Demonstration Project

NASA Astrophysics Data System (ADS)

Widyolar, Bennett K.

A solar thermal cooling system using novel non-tracking External Compound Parabolic Concentrators (XCPC) has been built at the University of California, Merced and operated for two cooling seasons. Its performance in providing power for space cooling has been analyzed. This solar cooling system is comprised of 53.3 m2 of XCPC trough collectors which are used to power a 23 kW double effect (LiBr) absorption chiller. This is the first system that combines both XCPC and absorption chilling technologies. Performance of the system was measured in both sunny and cloudy conditions, with both clean and dirty collectors. It was found that these collectors are well suited at providing thermal power to drive absorption cooling systems and that both the coinciding of available thermal power with cooling demand and the simplicity of the XCPC collectors compared to other solar thermal collectors makes them a highly attractive candidate for cooling projects.

Conceptual design study of concentrator enhanced solar arrays for space applications. Performance evaluation of 5 KW and 20 KW systems in Si and GaAs at 1 AU employing a flat plate trough concentrator

NASA Technical Reports Server (NTRS)

1980-01-01

A simple, efficient and very lightweight preliminary design for a 5 KW and 20 KW BOL output concentrated array evolved and is described by drawings. The relative effectiveness of this design, as compared to an unconcentrated planar array of equal power output, was measured by comparing power to mass performance of and the solar cell area required by each. Improvements in power to mass performance as high as 42% together with array area size reduction of 57% are possible in GaAs systems. By contrast, when the same concentrator design is applied to silicon systems, no improvement in power to mass can be obtained although array area reductions as high as 35% are obtainable.

Performance evaluation and simulation of a Compound Parabolic Concentrator (CPC) trough Solar Thermal Power Plant in Puerto Rico under solar transient conditions

NASA Astrophysics Data System (ADS)

Feliciano-Cruz, Luisa I.

The increasing fossil fuel costs as well as the need to move in a somewhat sustainable future has led the world in a quest for exploiting the free and naturally available energy from the Sun to produce electric power, and Puerto Rico is no exception. This thesis proposes the design of a simulation model for the analysis and performance evaluation of a Solar Thermal Power Plant in Puerto Rico and suggests the use of the Compound Parabolic Concentrator as the solar collector of choice. Optical and thermal analysis of such collectors will be made using local solar radiation data for determining the viability of this proposed project in terms of the electric power produced and its cost.

Comparative performance of solar thermal power generation concepts

NASA Technical Reports Server (NTRS)

Wen, L.; Wu, Y. C.

1976-01-01

A performance comparison is made between the central receiver system (power tower) and a distributed system using either dishes or troughs and lines to transport fluids to the power station. These systems were analyzed at a rated capacity of 30 MW of thermal energy delivered in the form of superheated steam at 538 C (1000 F) and 68 atm (1000 psia), using consistent weather data, collector surface waviness, pointing error, and electric conversion efficiency. The comparisons include technical considerations for component requirements, land utilization, and annual thermal energy collection rates. The relative merits of different representative systems are dependent upon the overall conversion as expressed in the form of performance factors in this paper. These factors are essentially indices of the relative performance effectiveness for different concepts based upon unit collector area. These performance factors enable further economic tradeoff studies of systems to be made by comparing them with projected production costs for these systems.

Start-up performance of parabolic trough concentrating solar power plants

NASA Astrophysics Data System (ADS)

Ferruzza, Davide; Topel, Monika; Basaran, Ibrahim; Laumert, Björn; Haglind, Fredrik

2017-06-01

Concentrating solar power plants, even though they can be integrated with thermal energy storage, are still subjected to cyclic start-up and shut-downs. As a consequence, in order to maximize their profitability and performance, the flexibility with respect to transient operations is essential. In this regard, two of the key components identified are the steam generation system and steam turbine. In general it is desirable to have fast ramp-up rates during the start-up of a power plant. However ramp-up rates are limited by, among other things, thermal stresses, which if high enough can compromise the life of the components. Moreover, from an operability perspective it might not be optimal to have designs for the highest heating rates, as there may be other components limiting the power plant start-up. Therefore, it is important to look at the interaction between the steam turbine and steam generator to determine the optimal ramp rates. This paper presents a methodology to account for thermal stresses limitations during the power plant start up, aiming at identifying which components limit the ramp rates. A detailed dynamic model of a parabolic trough power plant was developed and integrated with a control strategy to account for the start-up limitations of both the turbine and steam generator. The models have been introduced in an existing techno-economic tool developed by the authors (DYESOPT). The results indicated that for each application, an optimal heating rates range can be identified. For the specific case presented in the paper, an optimal range of 7-10 K/min of evaporator heating rate can result in a 1.7-2.1% increase in electricity production compared to a slower component (4 K/min).

Concentrating Solar Power Projects - Chabei 64MW Molten Salt Parabolic

Science.gov Websites

project Status Date: September 29, 2016 Project Overview Project Name: Chabei 64MW Molten Salt Parabolic Technology: Parabolic trough Turbine Capacity: Net: 64.0 MW Gross: 64.0 MW Status: Under development Do you have more information, corrections, or comments? Background Technology: Parabolic trough Status: Under

LCOE reduction potential of parabolic trough and solar tower CSP technology until 2025

NASA Astrophysics Data System (ADS)

Dieckmann, Simon; Dersch, Jürgen; Giuliano, Stefano; Puppe, Michael; Lüpfert, Eckhard; Hennecke, Klaus; Pitz-Paal, Robert; Taylor, Michael; Ralon, Pablo

2017-06-01

Concentrating Solar Power (CSP), with an installed capacity of 4.9 GW by 2015, is a young technology compared to other renewable power generation technologies. A limited number of plants and installed capacity in a small challenging market environment make reliable and transparent cost data for CSP difficult to obtain. The International Renewable Energy Agency (IRENA) and the DLR German Aerospace Center gathered and evaluated available cost data from various sources for this publication in order to yield transparent, reliable and up-to-date cost data for a set of reference parabolic trough and solar tower plants in the year 2015 [1]. Each component of the power plant is analyzed for future technical innovations and cost reduction potential based on current R&D activities, ongoing commercial developments and growth in market scale. The derived levelized cost of electricity (LCOE) for 2015 and 2025 are finally contrasted with published power purchase agreements (PPA) of the NOOR II+III power plants in Morocco. At 7.5% weighted average cost of capital (WACC) and 25 years economic life time, the levelized costs of electricity for plants with 7.5 (trough) respectively 9 (tower) full-load hours thermal storage capacity decrease from 14-15 -ct/kWh today to 9-10 -ct/kWh by 2025 for both technologies at direct normal irradiation of 2500 kWh/(m².a). The capacity factor increases from 41.1% to 44.6% for troughs and from 45.5% to 49.0% for towers. Financing conditions are a major cost driver and offer potential for further cost reduction with the maturity of the technology and low interest rates (6-7 - ct/kWh for 2% WACC at 2500 kWh/(m2.a) in 2025).

Hydrogen generation in CSP plants and maintenance of DPO/BP heat transfer fluids - A simulation approach

NASA Astrophysics Data System (ADS)

Kuckelkorn, Thomas; Jung, Christian; Gnädig, Tim; Lang, Christoph; Schall, Christina

2016-05-01

The ageing of diphenyl oxide/ biphenyl (DPO/BP) Heat Transfer Fluids (HTFs) implies challenging tasks for operators of parabolic trough power plants in order to find the economic optimum between plant performance and O&M costs. Focusing on the generation of hydrogen, which is effecting from the HTF ageing process, the balance of hydrogen pressure in the HTF is simulated for different operation scenarios. Accelerated build-up of hydrogen pressure in the HTF is causing increased permeation into the annular vacuum space of the installed receivers and must be avoided in order to maintain the performance of these components. Therefore, the effective hydrogen partial pressure in the HTF has to be controlled and limited according to the specified values so that the vacuum lifetime of the receivers and the overall plant performance can be ensured. In order to simulate and visualize the hydrogen balance of a typical parabolic trough plant, initially a simple model is used to calculate the balance of hydrogen in the system and this is described. As input data for the simulation, extrapolated hydrogen generation rates have been used, which were calculated from results of lab tests performed by DLR in Cologne, Germany. Hourly weather data, surface temperatures of the tubing system calculated by using the simulation tool from NREL, and hydrogen permeation rates for stainless steel and carbon steel grades taken from literature have been added to the model. In a first step the effect of HTF ageing, build-up of hydrogen pressure in the HTF and hydrogen loss rates through piping and receiver components have been modeled. In a second step a selective hydrogen removal process has been added to the model. The simulation results are confirming the need of active monitoring and controlling the effective hydrogen partial pressure in parabolic trough solar thermal power plants with DPO/BP HTF. Following the results of the simulation, the expected plant performance can only be achieved over lifetime, if the hydrogen partial pressure is actively controlled and limited.

Optical and mechanical tolerances in hybrid concentrated thermal-PV solar trough.

PubMed

Diaz, Liliana Ruiz; Cocilovo, Byron; Miles, Alexander; Pan, Wei; Blanche, Pierre-Alexandre; Norwood, Robert A

2018-05-14

Hybrid thermal-PV solar trough collectors combine concentrated photovoltaics and concentrated solar power technology to harvest and store solar energy. In this work, the optical and mechanical requirements for optimal efficiency are analyzed using non-sequential ray tracing techniques. The results are used to generate opto-mechanical tolerances that can be compared to those of traditional solar collectors. We also explore ideas on how to relieve tracking tolerances for single-axis solar collectors. The objective is to establish a basis for tolerances required for the fabrication and manufacturing of hybrid solar trough collectors.

Operating results of a thermocline thermal energy storage included in a parabolic trough mini power plant

NASA Astrophysics Data System (ADS)

Fasquelle, Thomas; Falcoz, Quentin; Neveu, Pierre; Lecat, Florent; Boullet, Nicolas; Flamant, Gilles

2017-06-01

A thermocline thermal energy storage tank consists in using one single tank to store sensible heat. At almost any time, three zones coexist in the tank: a hot fluid zone at the top, a cold fluid zone at the bottom, and an intermediate zone called thermocline. Filling the tank with solid materials enables to reduce cost and to maintain the thermal stratification during stand-by periods. The present paper deals with a 230 kWh experimental thermocline tank that is included into a 150 kWth parabolic trough mini power plant. The heat transfer fluid is a non-pressurized synthetic oil (dibenzyltoluene) that flows through alumina spheres in the storage tank. The solid materials are contained into baskets in order to facilitate their removing and replacement. Thermocouples measure temperature along the center of the cylinder and along its radius. It is therefore possible to study the thermocline behavior thanks to the measured temperature profiles. A typical charge, a typical discharge and a stand-by process are presented and storage performances are discussed. The behavior of the tank in a dynamic system is also considered, by analyzing a typical day of solar production and storage of the energy surplus.

Molten salt parabolic trough system with synthetic oil preheating

NASA Astrophysics Data System (ADS)

Yuasa, Minoru; Hino, Koichi

2017-06-01

Molten salt parabolic trough system (MSPT), which can heat the heat transfer fluid (HTF) to 550 °C has a better performance than a synthetic oil parabolic trough system (SOPT), which can heat the HTF to 400 °C or less. The utilization of HTF at higher temperature in the parabolic trough system is able to realize the design of a smaller size of storage tank and higher heat to electricity conversion efficiency. However, with MSPT there is a great amount of heat loss at night so it is necessary to circulate the HTF at a high temperature of about 290 °C in order to prevent solidification. A new MSPT concept with SOPT preheating (MSSOPT) has been developed to reduce the heat loss at night. In this paper, the MSSOPT system, its performance by steady state analysis and annual performance analysis are introduced.

Concentrating Solar Power Projects - Solnova 4 | Concentrating Solar Power

Science.gov Websites

, 2017 Project Overview Project Name: Solnova 4 Country: Spain Location: Sevilla (Sanlúcar la Mayor Technology: Parabolic trough Status: Operational Country: Spain City: Sevilla Region: Sanlúcar la Mayor Lat

Concentrating Solar Power Projects - Solnova 1 | Concentrating Solar Power

Science.gov Websites

, 2017 Project Overview Project Name: Solnova 1 Country: Spain Location: Sevilla (Sanlúcar la Mayor Technology: Parabolic trough Status: Operational Country: Spain City: Sevilla Region: Sanlúcar la Mayor Lat

Concentrating Solar Power Projects - Casablanca | Concentrating Solar Power

Science.gov Websites

(Badajoz) Owner(s): ACS - COBRA group (100%) Technology: Parabolic trough Turbine Capacity: Net: 50.0 MW Participants Developer(s): ACS - COBRA group Owner(s) (%): ACS - COBRA group (100%) EPC Contractor: Cobra

Concentrating Solar Power Projects - La Dehesa | Concentrating Solar Power

Science.gov Websites

| NREL Dehesa This page provides information on La Dehesa, a concentrating solar power (CSP : March 20, 2017 Project Overview Project Name: La Dehesa Country: Spain Location: La Garrovilla (Badajoz ? Background Technology: Parabolic trough Status: Operational Country: Spain City: La Garrovilla Region

Reflector Technology Development and System Design for Concentrating Solar Power Technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Adam Schaut

2011-12-30

Alcoa began this program in March of 2008 with the goal of developing and validating an advanced CSP trough design to lower the levelized cost of energy (LCOE) as compared to existing glass based, space-frame trough technology. In addition to showing a pathway to a significant LCOE reduction, Alcoa also desired to create US jobs to support the emerging CSP industry. Alcoa's objective during Phase I: Concept Feasibility was to provide the DOE with a design approach that demonstrates significant overall system cost savings without sacrificing performance. Phase I consisted of two major tasks; reflector surface development and system conceptmore » development. Two specific reflective surface technologies were investigated, silver metallized lamination, and thin film deposition both applied on an aluminum substrate. Alcoa prepared samples; performed test validation internally; and provided samples to the NREL for full-spectrum reflectivity measurements. The final objective was to report reflectivity at t = 0 and the latest durability results as of the completion of Phase 1. The target criteria for reflectance and durability were as follows: (1) initial (t = 0), hemispherical reflectance >93%, (2) initial spectral reflectance >90% for 25-mrad reading and >87% for 7-mrad reading, and (3) predicted 20 year durability of less than 5% optical performance drop. While the results of the reflective development activities were promising, Alcoa was unable to down-select on a reflective technology that met the target criteria. Given the progress and potential of both silver film and thin film technologies, Alcoa continued reflector surface development activities in Phase II. The Phase I concept development activities began with acquiring baseline CSP system information from both CSP Services and the DOE. This information was used as the basis to develop conceptual designs through ideation sessions. The concepts were evaluated based on estimated cost and high-level structural performance. The target criteria for the concept development was to achieve a solar field cost savings of 25%-50% thereby meeting or exceeding the DOE solar field cost savings target of $350/m2. After evaluating various structural design approaches, Alcoa down-selected to a monocoque, dubbed Wing Box, design that utilizes the reflective surface as a structural, load carrying member. The cost and performance potential of the Wing Box concept was developed via initial finite element analysis (FEA) and cost modeling. The structural members were sized through material utilization modeling when subjected to representative loading conditions including wind loading. Cost modeling was utilized to refine potential manufacturing techniques that could be employed to manufacture the structural members. Alcoa concluded that an aluminum intensive collector design can achieve significant cost savings without sacrificing performance. Based on the cost saving potential of this Concept Feasibility study, Alcoa recommended further validation of this CSP approach through the execution of Phase II: Design and Prototype Development. Alcoa Phase II objective was to provide the DOE with a validated CSP trough design that demonstrates significant overall system cost savings without sacrificing performance. Phase II consisted of three major tasks; Detail System Design, Prototype Build, and System Validation. Additionally, the reflector surface development that began in Phase I was continued in Phase II. After further development work, Alcoa was unable to develop a reflective technology that demonstrated significant performance or cost benefits compared to commercially available CSP reflective products. After considering other commercially available reflective surfaces, Alcoa selected Alano's MIRO-SUN product for use on the full scale prototype. Although MIRO-SUN has a lower specular reflectivity compared to other options, its durability in terms of handling, cleaning, and long-term reflectivity was deemed the most important attribute to successfully validate Alcoa's advanced trough architecture. To validate the performance of the Wing Box trough, a 6 meter aperture by 14 meter long prototype trough was built. For ease of shipping to and assembly at NREL's test facility, the prototype was fabricated in two half modules and joined along the centerline to create the Wing Box trough. The trough components were designed to achieve high precision of the reflective surface while leveraging high volume manufacturing and assembly techniques.« less

Effect of Channel Catfish Ictalurus Punctatus Egg Mass Loading Rate on Performance of the “See-Saw” Incubator

USDA-ARS?s Scientific Manuscript database

The “See-Saw” is a vertical-lift incubator that increases water circulation around and through channel catfish egg masses. Baskets in the incubator move up and down on racks in conventional hatchery troughs, raising the rack in one trough while lowering the rack in the adjacent trough. Egg masses ...

Simulation of hybrid solar power plants

NASA Astrophysics Data System (ADS)

Dieckmann, Simon; Dersch, Jürgen

2017-06-01

Hybrid solar power plants have the potential to combine advantages of two different technologies at the cost of increased complexity. The present paper shows the potential of the software greenius for the techno-economic evaluation of hybrid solar power plants and discusses two exemplary scenarios. Depreciated Concentrated Solar Power (CSP) plants based on trough technology can be retrofitted with solar towers in order to reach higher steam cycle temperatures and hence efficiencies. Compared to a newly built tower plant the hybridization of a depreciated trough plant causes about 30% lower LCOE reaching 104 /MWh. The second hybrid scenario combines cost-efficient photovoltaics with dispatchable CSP technology. This hybrid plant offers very high capacity factors up to 69% based on 100% load from 8am to 11pm. The LCOE of the hybrid plant are only slightly lower (174 vs. 186 /MWh) compared to the pure CSP plant because the capital expenditure for thermal storage and power block remains the same while the electricity output is much lower.

Concentrating Solar Power Projects - Shams 1 | Concentrating Solar Power |

Science.gov Websites

trough Turbine Capacity: Net: 100.0 MW Gross: 100.0 MW Status: Operational Start Year: 2013 Do you have Ground: July 2010 Start Production: March 17, 2013 Cost (approx): 600,000,000 USD PPA/Tariff Type

DETAIL VIEW OF CLASSIFIER, TAILINGS LAUNDER TROUGH, LINE SHAFTS, AND ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

DETAIL VIEW OF CLASSIFIER, TAILINGS LAUNDER TROUGH, LINE SHAFTS, AND CONCENTRATION TABLES, LOOKING SOUTHWEST. SLURRY EXITING THE BALL MILL WAS COLLECTED IN AN AMALGAMATION BOX (MISSING) FROM THE END OF THE MILL, AND INTRODUCED INTO THE CLASSIFIER. THE TAILINGS LAUDER IS ON THE GROUND AT LOWER RIGHT. THE LINE SHAFTING ABOVE PROVIDED POWER TO THE CONCENTRATION TABLES BELOW AT CENTER RIGHT. - Gold Hill Mill, Warm Spring Canyon Road, Death Valley Junction, Inyo County, CA

Case study of a central-station grid-intertie photovoltaic system with V-trough concentration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Freilich, J.; Gordon, J.M.

1991-01-01

This presentation is a cast study of an installed, central-station (no storage), utility-intertie photovoltaic (PV) system in Sede Boqer, Israel (latitude 30.9{degree}N). The nominally 12 kW peak PV system is comprised of 189 polycrystalline silicon modules mounted on inexpensive, one-axis north-south horizontal trackers with V-trough mirrors for optical boost. The power conditioning unit operates at a fixed voltage rather than at maximum power point (MPP). The primary task in analyzing the installed system was to investigate the cause of measured power output significantly below the design predictions of the installers, and to recommend system design modifications. Subsequent tasks included themore » quantitative assessment of fixed-voltage operation and of the energetic value of V-trough concentration and one-axis tracking for this system. Sample results show: (1) fixed-voltage operation at the best fixed voltage (BFV) can achieve around 96% of the yearly energy of MPP operation; (2) the sensitivity of the yearly energy delivery to the selection of fixed voltage and its marked asymmetry about the BFV; (3) the influences of inverter current constraints on yearly energy delivery and BFV; and (4) how the separate effects of tracking and optical concentration increase yearly energy delivery.« less

Concentrating Solar Power Projects - Astexol II | Concentrating Solar Power

Science.gov Websites

(Badajoz) Owner(s): Elecnor/Aries/ABM AMRO (100%) Technology: Parabolic trough Turbine Capacity: Net: 50.0 Difference: 100°C Power Block Turbine Capacity (Gross): 50.0 MW Turbine Capacity (Net): 50.0 MW Output Type indirect Storage Capacity: 8 Hours Thermal Storage Description:

Evaluation of parasitic consumption for a CSP plant

NASA Astrophysics Data System (ADS)

Ramorakane, Relebohile John; Dinter, Frank

2016-05-01

With the continuous development and desire to build alternative effective and efficient power plants, Concentrated Solar Power (CSP) plants (and more specifically the Parabolic Trough CSP Plants) have proven to be one of the alternative energy resources for the future. On this regard more emphasis and research is being employed to better this power plant technology, where one of the main challenges to these plants is to improve their efficiency by optimizing the parasitic load, wherein one of the major causes of the power plants' reduced overall efficiency arises from their parasitic load consumption. This project is therefore aimed at evaluating the parasitic load on Andasol 3 Power Plant, which is a 50 MW Parabolic Trough Power Plant with a 7.5 hours of full load storage system. It was hence determined that the total power plant's parasitic load consumption is about 12% in summer season and between 16% and 24% in winter season. In an effort to improve the power plant's efficiency, a couple of measures to reduce the parasitic load consumption were recommended, and also an alternative and cheaper source of parasitic load feeding plant, during the day (when the parasitic load consumption is highest) was proposed/recommended.

Initial appraisal of solar thermal electric energy in Tibet and Xinjiang Provinces, People`s Republic of China

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li Junfeng; Zhu Li; Liu Zhan

1998-07-01

At the request of US sponsors Spencer Management Associates (SMA) and Sun{diamond}Lab, China`s Center for Renewable Energy Development and former Ministry of Electric Power conducted an initial appraisal of the issues involved with developing China`s first solar thermal electric power plant in the sunbelt regions of Tibet or Xinjiang provinces. The appraisal concerns development of a large-scale, grid-connected solar trough or tower project capable of producing 30 or more megawatts of electricity. Several of the findings suggest that Tibet could be a niche market for solar thermal power because a solar plant may be the low-cost option relative to othermore » methods of generating electricity. China has studied the concept of a solar thermal power plant for quite some time. In 1992, it completed a pre-feasibility study for a SEGS-type parabolic trough plant with the aid of Israel`s United Development Limited. Because the findings were positive, both parties agreed to conduct a full-scale feasibility study. However, due to funding constraints, the study was postponed. Most recently, Sun{diamond}Lab and SMA asked China to broaden the analysis to include tower as well as trough concepts. The findings of this most recent investigation completed i November of 1997, are the subject of this paper. The main conclusions of all studies conducted to date suggest that a region in the proximity of Lhasa, Tibet, offers the best near-term opportunity within China. The opportunities for solar thermal power plants in other regions of China were also investigated.« less

A fixed tilt solar collector employing reversible vee-trough reflectors and vacuum tube receivers for solar heating and cooling systems

NASA Technical Reports Server (NTRS)

Selcuk, M. K.

1977-01-01

The usefulness of vee-trough concentrators in improving the efficiency and reducing the cost of collectors assembled from evacuated tube receivers was studied in the vee-trough/vacuum tube collector (VTVTC) project. The VTVTC was analyzed rigorously and various mathematical models were developed to calculate the optical performance of the vee-trough concentrator and the thermal performance of the evacuated tube receiver. A test bed was constructed to verify the mathematical analyses and compare reflectors made out of glass, Alzak and aluminized FEP Teflon. Tests were run at temperatures ranging from 95 to 180 C. Vee-trough collector efficiencies of 35 to 40% were observed at an operating temperature of about 175 C. Test results compared well with the calculated values. Predicted daily useful heat collection and efficiency values are presented for a year's duration of operation temperatures ranging from 65 to 230 C. Estimated collector costs and resulting thermal energy costs are presented. Analytical and experimental results are discussed along with a complete economic evaluation.

On-line monitoring of H2 generation and the HTF degradation in parabolic trough solar thermal power plants: Development of an optical sensor based on an innovative approach

NASA Astrophysics Data System (ADS)

Pagola, Iñigo; Funcia, Ibai; Sánchez, Marcelino; Gil, Javier; González-Vallejo, Victoria; Bedoya, Maxi; Orellana, Guillermo

2017-06-01

The work presented in this paper offers a robust, effective and economically competitive method for online detection and monitoring of the presence of molecular hydrogen in the heat transfer fluids of parabolic trough collector plants. The novel method is based on a specific fluorescent sensor according to the ES2425002 patent ("Method for the detection and quantification of hydrogen in a heat transfer fluid").

On the Path to SunShot: Advancing Concentrating Solar Power Technology Performance and Dispatchability.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mehos, Mark; Turchi, Craig; Jorgensen, Jennie

2016-03-01

Since the SunShot Vision Study (DOE 2012) was published, global deployment of concentrating solar power (CSP) has increased threefold to nearly 4,500 MW, with a similar threefold increase in operational capacity to 1,650 MW within the United States. Growth in U.S. CSP capacity has primarily been driven by policy support at the state and federal levels. State-driven renewable portfolio standards (RPSs), combined with a 30% federal investment tax credit (ITC) and federal loan guarantees, provided the opportunity for CSP developers to kick-start construction of CSP plants throughout the Southwest. Figure ES-1 demonstrates that deployment and private- and public-sector research andmore » development have led to dramatic cost reductions that have placed CSP well on the path to reaching the U.S. Department of Energy’s SunShot Initiative goal of 6 cents/kWh by 2020. In comparing the estimated capital costs from the SunShot Vision Study and the current analysis, we find that parabolic trough solar-field costs have fallen more rapidly than predicted, although the drop in solar-field costs was offset by the additional costs of moving from a wet-cooled power block in 2010 to a more expensive dry-cooled power block in 2015. The predicted 2015 decline in tower costs was in line with expectations, primarily driven by reduced heliostat costs. Figure ES-1 shows the reduction in levelized cost of electricity (LCOE) for both parabolic trough and tower systems, in addition to the projected 2020 SunShot target.« less

Calprotectin and TNF trough serum levels identify power Doppler ultrasound synovitis in rheumatoid arthritis and psoriatic arthritis patients in remission or with low disease activity.

PubMed

Inciarte-Mundo, José; Ramirez, Julio; Hernández, Maria Victoria; Ruiz-Esquide, Virginia; Cuervo, Andrea; Cabrera-Villalba, Sonia Raquel; Pascal, Mariona; Yagüe, Jordi; Cañete, Juan D; Sanmarti, Raimon

2016-07-08

Serum levels of calprotectin, a major S100 leucocyte protein, are associated with disease activity in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients. Higher drug trough serum levels are associated with good response in patients treated with tumour necrosis factor inhibitors (TNFi). Power Doppler ultrasound (PDUS) synovitis is predictive of flare and progression of structural damage in patients in clinical remission. The purpose of this study was to analyse the accuracy of calprotectin and TNFi trough serum levels in detecting PDUS synovitis in RA and PsA patients in clinical remission or with low disease activity who were receiving TNFi. We conducted a cross-sectional study of 92 patients (42 with RA, 50 with PsA) receiving adalimumab (ADA), etanercept (ETN) or infliximab who were in remission or had low disease activity (28-joint Disease Activity Score based on erythrocyte sedimentation rate <3.2). Associations of calprotectin, TNFi trough serum levels and acute phase reactants with PDUS synovitis were assessed using correlation and linear regression analyses. The accuracy and discriminatory capacity in detecting PDUS synovitis was assessed using ROC curves. PDUS synovitis was found in 62.4 % of RA patients and 32 % of PsA patients. Both RA and PsA patients with PDUS synovitis had higher calprotectin levels and lower TNFi trough serum levels. Calprotectin positively correlated with ultrasound scores (all r coefficients >0.50 in RA). Calprotectin correlated with the PDUS synovitis score in patients treated with ADA and ETN. Using PDUS synovitis (yes or no) as the reference variable, calprotectin had an AUC of 0.826. The best cut-off was ≥1.66 μg/ml, with a likelihood ratio of 2.77. C-reactive protein (AUC 0.673) and erythrocyte sedimentation rate (AUC 0.731) had a lower discriminatory capacity. TNFi trough serum levels were significantly associated with PDUS synovitis (OR 0.67, 95 % CI 0.52-0.85, p < 0.001) but their accuracy (AUC <0.5) was less than that of calprotectin. TNFi trough serum levels were inversely correlated with calprotectin and PDUS synovitis in RA and PsA patients receiving ADA and ETN. Calprotectin and TNFi trough serum levels may help identify PDUS synovitis in RA and PsA patients in clinical remission or with low disease activity.

Solar-power mountain concept

NASA Technical Reports Server (NTRS)

Clarke, V. C., Jr.

1977-01-01

Solar collectors on mountainside collect thermal energy for mountaintop powerplant. Sloped arrangement reduces heat-transport problem of level ground-based collector field. Heated air rises without mechanical pumps and buoyancy force supplies pumping power without further cost. Precision tracking requirement of power towers eliminated by butted-together Winston-type concentrator troughs. Low-cost native rock is used for heat storage.

Concentrating Solar Power Projects - Majadas I | Concentrating Solar Power

Science.gov Websites

: March 20, 2017 Project Overview Project Name: Majadas I Country: Spain Location: Majadas de Tiétar (Cà comments? Background Technology: Parabolic trough Status: Operational Country: Spain City: Majadas de Tià : Biphenyl/Diphenyl oxide Solar-Field Outlet Temp: 393°C Power Block Turbine Capacity (Gross): 50.0 MW

Monitoring of seafloor crustal deformation using GPS/Acoustic technique along the Nankai Trough, Japan

NASA Astrophysics Data System (ADS)

Yasuda, K.; Tadokoro, K.; Ikuta, R.; Watanabe, T.; Fujii, C.; Matsuhiro, K.; Sayanagi, K.

2014-12-01

Seafloor crustal deformation is crucial for estimating the interplate locking at the shallow subduction zone and has been carried out at subduction margins in Japan, e.g., Japan Trench and Nankai Trough [Sato et al., 2011; Tadokoro et al., 2012]. Iinuma et al. [2012] derived slip distributions during the 2011 Tohoku-Oki earthquake using GPS/Acoustic data and on-land GPS data. The result showed that maximum slip is more than 85 m near the trench axis. The focal area along the Nankai trough extended to the trough axis affected this earthquake by cabinet office, government of Japan. 　We monitored seafloor crustal deformation along the Nankai trough, Japan. Observation regions are at the eastern end of Nankai trough (named Suruga trough) and at the central Nankai trough. We established and monitored by two sites across the trough at each region. In the Suruga trough region, we repeatedly observed from 2005 to 2013. We observed 13 and 14 times at a foot wall side (SNE) and at a hanging wall side (SNW), respectively. We estimated the displacement velocities with relative to the Amurian plate from the result of repeated observation. The estimated displacement velocity vectors at SNE and SNW are 42±8 mm/y to N94±3˚W direction and 39±11 mm/y to N84±9˚W direction, respectively. The directions are the same as those measured at the on-land GPS stations. The magnitudes of velocity vector indicate significant shortening by approximately 4 mm/y between SNW and on-land GPS stations at hanging wall side of the Suruga Trough. This result shows that the plate interface at the northernmost Suruga trough is strongly locked. In the central Nankai trough region, we established new two stations across the central Nankai trough (Both stations are about 15km distance from trough) and observed only three times, August 2013, January 2014, and June 2014. We report the results of monitoring performed in this year.

Sensitivity analysis on the effect of key parameters on the performance of parabolic trough solar collectors

NASA Astrophysics Data System (ADS)

Muhlen, Luis S. W.; Najafi, Behzad; Rinaldi, Fabio; Marchesi, Renzo

2014-04-01

Solar troughs are amongst the most commonly used technologies for collecting solar thermal energy and any attempt to increase the performance of these systems is welcomed. In the present study a parabolic solar trough is simulated using a one dimensional finite element model in which the energy balances for the fluid, the absorber and the envelope in each element are performed. The developed model is then validated using the available experimental data . A sensitivity analysis is performed in the next step in order to study the effect of changing the type of the working fluid and the corresponding Reynolds number on the overall performance of the system. The potential improvement due to the addition of a shield on the upper half of the annulus and enhancing the convection coefficient of the heat transfer fluid is also studied.

Solar thermal power & gas turbine hybrid design with molten salt storage tank

NASA Astrophysics Data System (ADS)

Martín, Fernando; Wiesenberg, Ralf; Santana, Domingo

2017-06-01

Taking into consideration the need to decelerate the global climatic change, power generation has to shift from burning fossil fuel to renewable energy source in short medium period of time. In this work, we are presenting a new model of a solar-gas natural hybrid power cycle with the main aim of decoupling the solar generation system from the gas turbine system. The objective is to have high solar power contribution compared to conventional ISCC plants [2], producing firm and dispatchable electricity at the same time. The decoupling is motivated by the low solar contribution reached by the ISCC, which is technically limited to maximum of 15%, [4]. In our case, we have implemented a solar tower with molten salts as working fluid. Central receiver systems get higher performance than others systems, like parabolic trough technology [1], due to the higher temperature achieved in the heat transferred fluid HTF, close to 560°C.

System and Method for Modeling the Flow Performance Features of an Object

NASA Technical Reports Server (NTRS)

Jorgensen, Charles (Inventor); Ross, James (Inventor)

1997-01-01

The method and apparatus includes a neural network for generating a model of an object in a wind tunnel from performance data on the object. The network is trained from test input signals (e.g., leading edge flap position, trailing edge flap position, angle of attack, and other geometric configurations, and power settings) and test output signals (e.g., lift, drag, pitching moment, or other performance features). In one embodiment, the neural network training method employs a modified Levenberg-Marquardt optimization technique. The model can be generated 'real time' as wind tunnel testing proceeds. Once trained, the model is used to estimate performance features associated with the aircraft given geometric configuration and/or power setting input. The invention can also be applied in other similar static flow modeling applications in aerodynamics, hydrodynamics, fluid dynamics, and other such disciplines. For example, the static testing of cars, sails, and foils, propellers, keels, rudders, turbines, fins, and the like, in a wind tunnel, water trough, or other flowing medium.

NREL's Education Program in Action in the Concentrating Solar Power Program Advanced Materials Task

NASA Astrophysics Data System (ADS)

Kennedy, Cheryl

2010-03-01

Concentrating solar power (CSP) technologies use large mirrors to concentrate sunlight and the thermal energy collected is converted to electricity. The CSP industry is growing rapidly and is expected to reach 25 GW globally by 2020. Cost target goals are for CSP technologies to produce electricity competitive with intermediate-load power generation (i.e., natural gas) by 2015 with 6 hours of thermal storage and competitive in carbon constrained base load power markets (i.e., coal) by 2020 with 12-17 hours of thermal storage. The solar field contributes more than 40% of the total cost of a parabolic trough plant and together the mirrors and receivers contribute more than 25% of the installed solar field cost. CSP systems cannot hit these targets without aggressive cost reductions and revolutionary performance improvements from technology advances. NREL's Advanced Materials task in the CSP Advanced R&D project performs research to develop low cost, high performance, durable solar reflector and high-temperature receiver materials to meet these needs. The Advanced Materials task leads the world in this research and the task's reliance on NREL's educational program will be discussed.

Proceedings of the First Semiannual Distributed Receiver Program Review

NASA Technical Reports Server (NTRS)

1980-01-01

Point focus and line focus distributed receiver solar thermal technology for the production of electric power and of industrial process heat is addressed. Concentrator, receiver, and power conversion development are covered along with hardware tests and evaluation. Mass production costing, parabolic dish applications, and trough and bowl systems are included.

Currently used dosage regimens of vancomycin fail to achieve therapeutic levels in approximately 40% of intensive care unit patients.

PubMed

Obara, Vitor Yuzo; Zacas, Carolina Petrus; Carrilho, Claudia Maria Dantas de Maio; Delfino, Vinicius Daher Alvares

2016-01-01

This study aimed to assess whether currently used dosages of vancomycin for treatment of serious gram-positive bacterial infections in intensive care unit patients provided initial therapeutic vancomycin trough levels and to examine possible factors associated with the presence of adequate initial vancomycin trough levels in these patients. A prospective descriptive study with convenience sampling was performed. Nursing note and medical record data were collected from September 2013 to July 2014 for patients who met inclusion criteria. Eighty-three patients were included. Initial vancomycin trough levels were obtained immediately before vancomycin fourth dose. Acute kidney injury was defined as an increase of at least 0.3mg/dL in serum creatinine within 48 hours. Considering vancomycin trough levels recommended for serious gram-positive infection treatment (15 - 20µg/mL), patients were categorized as presenting with low, adequate, and high vancomycin trough levels (35 [42.2%], 18 [21.7%], and 30 [36.1%] patients, respectively). Acute kidney injury patients had significantly greater vancomycin trough levels (p = 0.0055, with significance for a trend, p = 0.0023). Surprisingly, more than 40% of the patients did not reach an effective initial vancomycin trough level. Studies on pharmacokinetic and dosage regimens of vancomycin in intensive care unit patients are necessary to circumvent this high proportion of failures to obtain adequate initial vancomycin trough levels. Vancomycin use without trough serum level monitoring in critically ill patients should be discouraged.

Integrated solar energy system optimization

NASA Astrophysics Data System (ADS)

Young, S. K.

1982-11-01

The computer program SYSOPT, intended as a tool for optimizing the subsystem sizing, performance, and economics of integrated wind and solar energy systems, is presented. The modular structure of the methodology additionally allows simulations when the solar subsystems are combined with conventional technologies, e.g., a utility grid. Hourly energy/mass flow balances are computed for interconnection points, yielding optimized sizing and time-dependent operation of various subsystems. The program requires meteorological data, such as insolation, diurnal and seasonal variations, and wind speed at the hub height of a wind turbine, all of which can be taken from simulations like the TRNSYS program. Examples are provided for optimization of a solar-powered (wind turbine and parabolic trough-Rankine generator) desalinization plant, and a design analysis for a solar powered greenhouse.

Seasonal variation and solar activity dependence of the quiet-time ionospheric trough

NASA Astrophysics Data System (ADS)

Ishida, T.; Ogawa, Y.; Kadokura, A.; Hiraki, Y.; Häggström, I.

2014-08-01

We have conducted a statistical analysis of the ionospheric F region trough, focusing on its seasonal variation and solar activity dependence under geomagnetically quiet and moderate conditions, using plasma parameter data obtained via Common Program 3 observations performed by the European Incoherent Scatter (EISCAT) radar between 1982 and 2011. We have confirmed that there is a major difference in frictional heating between the high- and low-latitude sides of the EISCAT field of view (FOV) at ~73°0'N-60°5'N (geomagnetic latitude) at an altitude of 325 km, which is associated with trough formation. Our statistical results show that the high-latitude and midlatitude troughs occur on the high- and low-latitude sides of the FOV, respectively. Seasonal variations indicate that dissociative recombination accompanied by frictional heating is a main cause of trough formation in sunlit regions. During summer, therefore, the occurrence rate is maintained at 80-90% in the postmidnight high-latitude region owing to frictional heating by eastward return flow. Solar activity dependence on trough formation indicates that field-aligned currents modulate the occurrence rate of the trough during the winter and equinox seasons. In addition, the trough becomes deeper via dissociative recombination caused by an increased ion temperature with F10.7, at least in the equinox and summer seasons but not in winter.

Concentrating Solar Power Projects - Holaniku at Keahole Point |

Science.gov Websites

: Currently Non-Operational Start Year: 2009 Do you have more information, corrections, or comments ? Background Technology: Parabolic trough Status: Currently Non-Operational Country: United States City

Concentrating Solar Power Projects - Extresol-2 | Concentrating Solar Power

Science.gov Websites

Sesmero (Badajoz) Owner(s): ACS/Cobra Group (100%) Technology: Parabolic trough Turbine Capacity: Net : 158,000 MWh/yr (Expected/Planned) Contact(s): Manuel Cortes; Ana Salazar Company: ACS/Cobra Group Break Project Type: Commercial Participants Developer(s): ACS/Cobra Group Owner(s) (%): ACS/Cobra Group (100

Concentrating Solar Power Projects - Extresol-3 | Concentrating Solar Power

Science.gov Websites

Sesmero (Badajoz) Owner(s): ACS/Cobra Group (100%) Technology: Parabolic trough Turbine Capacity: Net : 158,000 MWh/yr (Expected/Planned) Contact(s): Manuel Cortes; Ana Salazar Company: ACS/Cobra Group Break years Project Type: Commercial Participants Developer(s): ACS/Cobra Group Owner(s) (%): ACS/Cobra Group

Concentrating Solar Power Projects - Guzmán | Concentrating Solar Power |

Science.gov Websites

) Owner(s): FCC Energy (70%) Mitsui (30%) Technology: Parabolic trough Turbine Capacity: Net: 50.0 MW -Field Outlet Temp: 393°C Solar-Field Temp Difference: 100°C Power Block Turbine Capacity (Gross): 50.0 MW Turbine Capacity (Net): 50.0 MW Turbine Manufacturer: Man-Turbo Turbine Description: 5 extractions

Concentrating Solar Power Projects by Project Name | Concentrating Solar

Science.gov Websites

Tower Plant Gujarat Solar One Gulang 100MW Thermal Oil Parabolic Trough project Guzmán Hami 50 MW CSP ¼lich Solar Tower Kathu Solar Park KaXu Solar One Khi Solar One Kimberlina Solar Thermal Power Plant Solar Plant MINOS Mojave Solar Project Morón National Solar Thermal Power Facility Nevada Solar One

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mendelsohn, M.; Lowder, T.; Canavan, B.

Over the last several years, solar energy technologies have been, or are in the process of being, deployed at unprecedented levels. A critical recent development, resulting from the massive scale of projects in progress or recently completed, is having the power sold directly to electric utilities. Such 'utility-scale' systems offer the opportunity to deploy solar technologies far faster than the traditional 'behind-the-meter' projects designed to offset retail load. Moreover, these systems have employed significant economies of scale during construction and operation, attracting financial capital, which in turn can reduce the delivered cost of power. This report is a summary ofmore » the current U.S. utility-scale solar state-of-the-market and development pipeline. Utility-scale solar energy systems are generally categorized as one of two basic designs: concentrating solar power (CSP) and photovoltaic (PV). CSP systems can be further delineated into four commercially available technologies: parabolic trough, central receiver (CR), parabolic dish, and linear Fresnel reflector. CSP systems can also be categorized as hybrid, which combine a solar-based system (generally parabolic trough, CR, or linear Fresnel) and a fossil fuel energy system to produce electric power or steam.« less

Improvement Design of Parabolic Trough

NASA Astrophysics Data System (ADS)

Ihsan, S. I.; Safian, M. A. I. M.; Taufek, M. A. M.; Mohiuddin, A. K. M.

2017-03-01

The performance of parabolic trough solar collector (PTSC) has been evaluated using different heat transfer working fluids; namely water and SAE20 W50 engine oil. New and slightly improved PTSC was developed to run the experimental study. Under the meteorological conditions of Malaysia, authors found that PTSC can operate at a higher temperature than water collector but the performance efficiency of collector using engine oil is much lower than the water collector.

Concurrent immunomodulator therapy is associated with higher adalimumab trough levels during scheduled maintenance therapy.

PubMed

Bond, Ashley; Dodd, Susanna; Fisher, Gareth; Skouras, Thomas; Subramanian, Sreedhar

2017-02-01

Combination therapy with infliximab and immunomodulators is superior to monotherapy, resulting in better outcomes and higher trough levels of infliximab. The role of concurrent immunomodulatory therapy on adalimumab trough levels has not been adequately investigated. We evaluated the impact of concomitant immunomodulation on adalimumab trough levels in patients on scheduled maintenance therapy. We conducted a prospective observational, cross-sectional study of all inflammatory bowel disease patients on maintenance therapy who had adalimumab trough levels measured between January 2013 and January 2016. Drug level and anti-drug antibody measurements were performed on sera using a solid phase assay. Pairwise comparison of means was used to compare trough levels in patients with and without concomitant immune modulator therapy. In total, 79 patients were included. Twenty-three patients (29.1%) were on weekly dosing whereas 56 (70.9%) were on alternate weeks. Median adalimumab trough levels were comparable in patients with and without clinical remission (6.8 μg/ml (IQR 5.6-8.1) versus 6.7 μg/ml (IQR 3.9-8.1), respectively. Patients with an elevated faecal calprotectin >250 μg/g had lower adalimumab trough levels (median 6.7, IQR 3.9-8) compared to patients with faecal calprotectin <250 μg/g (median 7.7, IQR 6.1-8.1) though this did not achieve statistical significance (p = .062). Median adalimumab trough levels among patients on concurrent immunomodulators was 7.2 μg/ml (IQR 5.7-8.1) compared to those not on concurrent immunomodulator, 6.1 μg/ml (IQR 2.7-7.7, p = .0297). Adalimumab trough levels were significantly higher in patients on concurrent immunomodulators during maintenance therapy. There was a trend towards a lower adalimumab trough level in patients with elevated calprotectin.

Heat Transfer Phenomena in Concentrating Solar Power Systems.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Armijo, Kenneth Miguel; Shinde, Subhash L.

Concentrating solar power (CSP) utilizes solar thermal energy to drive a thermal power cycle for the generation of electricity. CSP systems are facilitated as large, centralized power plants , such as power towers and trough systems, to take advantage of ec onomies of scale through dispatchable thermal energy storage, which is a principle advantage over other energy generation systems . Additionally, the combination of large solar concentration ratios with high solar conversion efficiencies provides a strong o pportunity of employment of specific power cycles such as the Brayton gas cycle that utilizes super critical fluids such as supercritical carbon dioxidemore » (s CO 2 ) , compared to other sola r - fossil hybrid power plants. A comprehensive thermal - fluids examination is provided by this work of various heat transfer phenomena evident in CSP technologies. These include sub - systems and heat transfer fundamental phenomena evident within CSP systems , which include s receivers, heat transfer fluids (HTFs), thermal storage me dia and system designs , thermodynamic power block systems/components, as well as high - temperature materials. This work provides literature reviews, trade studies, and phenomenological comparisons of heat transfer media (HTM) and components and systems, all for promotion of high performance and efficient CSP systems. In addition, f urther investigations are also conducted that provide advanced heat transfer modeling approaches for gas - particle receiver systems , as well as performance/efficiency enhancement re commendations, particularly for solarized supercritical power systems .« less

Geospatial assessment of solar energy potential for utility scale parabolic trough collector power plant in Saudi Arabia

NASA Astrophysics Data System (ADS)

Ibarra, Mercedes; Gherboudj, Imen; Al Rished, Abdulaziz; Ghedira, Hosni

2017-06-01

Given ambitious plans to increase the amount of electricity production from renewable resources and the natural resources of the Kingdom of Saudi Arabia (KSA), solar energy stands as a technology with a great development potential in this country. In this work, the suitability of the territory is assess through a geospatial analysis, using a PTC performance model to account for the technical potential. As a result, a land suitability map is presented, where the North-West area of the country is identified as the one with more highly suitable area.

75 FR 41231 - Notice of Intent To Prepare an Environmental Impact Statement for the Proposed Abengoa Solar Inc...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-15

... concentrated solar power facility including a solar parabolic trough, photovoltaic panels, an electrical... a second 250-MW unit. Additionally, the proposal may include up to 20 MW of photovoltaic solar power... Statement for the Proposed Abengoa Solar Inc., Lathrop Wells Solar Facility, Amargosa Valley, Nye County, NV...

Concentrating Solar Power Projects - Solar Electric Generating Station VIII

Science.gov Websites

: Harper Dry Lake, California (Mojave Desert) Owner(s): NextEra (50%) Technology: Parabolic trough Turbine City: Harper Dry Lake State: California County: San Bernardino Region: Mojave Desert Lat/Long Location

Concentrating Solar Power Projects - Solar Electric Generating Station IX |

Science.gov Websites

Station IX (SEGS IX) Country: United States Location: Harper Dry Lake, California (Mojave Desert) Owner(s : Parabolic trough Status: Operational Country: United States City: Harper Dry Lake State: California County

Concentrating Solar Power Projects - ASE Demo Plant | Concentrating Solar

Science.gov Websites

: Parabolic trough Turbine Capacity: Gross: 0.35 MW Status: Operational Start Year: 2013 Do you have more Start Production: 2013 Project Type: Demonstration Participants Developer(s): Archimede Solar Energy

NREL, SPI Solar and Trimark Optimize Parabolic Trough Receiver Performance

Science.gov Websites

(CSP) plants. Photo of parabolic trough receiver equipment in a laboratory Photo by Dennis Schroeder Receivers in CSP plants take a lot of abuse, from dramatic temperature changes to numerous mechanical conditions can lead to big improvements in the overall efficiency of CSP plants

Optical analysis of a photovoltaic V-trough system installed in western India.

PubMed

Maiti, Subarna; Sarmah, Nabin; Bapat, Pratap; Mallick, Tapas K

2012-12-20

The low concentrating photovoltaic (PV) system such as a 2× V-trough system can be a promising choice for enhancing the power output from conventional PV panels with the inclusion of thermal management. This system is more attractive when the reflectors are retrofitted to the stationary PV panels installed in a high aspect ratio in the north-south direction and are tracked 12 times a year manually according to preset angles, thus eliminating the need of diurnal expensive tracking. In the present analysis, a V-trough system facing exactly the south direction is considered, where the tilt angle of the PV panels' row is kept constant at 18.34°. The system is installed on the terrace of CSIR-Central Salt and Marine Chemicals Research Institute in Bhavnagar, Gujarat, India (21.47 N, 71.15 E). The dimension of the entire PV system is 9.64 m×0.55 m. The V-troughs made of anodized aluminum reflectors (70% specular reflectivity) had the same dimensions. An in-house developed; experimentally validated Monte Carlo ray-trace model was used to study the effect of the angular variation of the reflectors throughout a year for the present assembly. Results of the ray trace for the optimized angles showed the maximum simulated optical efficiency to be 85.9%. The spatial distribution of solar intensity over the 0.55 m dimension of the PV panel due to the V-trough reflectors was also studied for the optimized days in periods that included solstices and equinoxes. The measured solar intensity profiles with and without the V-trough system were used to calculate the actual optical efficiencies for several sunny days in the year, and results were validated with the simulated efficiencies within an average error limit of 10%.

Role of CYP24A1, VDR and GC gene polymorphisms on deferasirox pharmacokinetics and clinical outcomes.

PubMed

Allegra, S; Cusato, J; De Francia, S; Arduino, A; Longo, F; Pirro, E; Massano, D; De Nicolò, A; Piga, A; D'Avolio, A

2018-05-22

β-Thalassemia patients develop deficiency in vitamin D absorption and liver hydroxylation, resulting in extremely low calcitriol levels. We explored the role of single-nucleotide polymorphisms (SNPs) involved in vitamin D metabolism, transport and activity on deferasirox pharmacokinetics and outcomes (effectiveness trough levels (C trough ) and the area under the curve (AUC) cutoffs of 20 μg ml -1 and 360 μg ml -1  h -1 , respectively; nonresponse AUC limit of 250 μg ml -1  h -1 ). Ninety-nine β-thalassemic patients were enrolled. Drug plasma C trough and AUC were measured by the high-performance liquid chromatography system coupled with an ultraviolet determination method. Allelic discrimination for VDR, CYP24A1, CYP27B1 and GC gene SNPs was performed by real-time PCR. CYP24A1 22776 TT significantly influenced C min and negatively predicted it in regression analysis. CYP24A1 3999 CC was associated with C trough and C min and was a negative predictor of T max , whereas CYP24A1 8620 GG seemed to have a role in C trough , AUC, t 1/2 and C min , and was an AUC negative predictor factor. Considering treatment outcome, Cdx2 and GC 1296 were retained in regression analysis as AUC efficacy cutoff negative predictors.

Concentrating Solar Power Projects - Xina Solar One | Concentrating Solar

Science.gov Websites

Power | NREL Xina Solar One Abengoa has been selected by the Department of Energy (DOE) of South Africa to develop Xina Solar One, a 100 MW parabolic trough plant with a five-hour thermal energy with Abengoa's plant KaXu Solar One that is currently under construction in the country. Xina Solar One

NREL Research Garners Three Prestigious R&D 100 Awards | News | NREL

Science.gov Websites

, SkyFuel, to create a ground-breaking and low-cost system for utility-sized power generation. The SkyTrough installation costs into competition with gas-fired power plants. NREL shares this award with SkyFuel, Inc. NREL -film lithium microbattery. Its ideal applications are remote wireless sensors, smart homes, smart cars

Concentrating Solar Power Projects - La Africana | Concentrating Solar

Science.gov Websites

: Posadas (Córdoba) Owner(s): Ortiz/TSK/Magtel (100%) Technology: Parabolic trough Turbine Capacity: Net -Field Outlet Temp: 393°C Solar-Field Temp Difference: 100°C Power Block Turbine Capacity (Gross): 50.0 MW Turbine Capacity (Net): 50.0 MW Output Type: Steam Rankine Cooling Method: Wet cooling Thermal

Supersonic burning in separated flow regions

NASA Technical Reports Server (NTRS)

Zumwalt, G. W.

1982-01-01

The trough vortex phenomena is used for combustion of hydrogen in a supersonic air stream. This was done in small sizes suitable for igniters in supersonic combustion ramjets so long as the boundary layer displacement thickness is less than 25% of the trough step height. A simple electric spark, properly positioned, ignites the hydrogen in the trough corner. The resulting flame is self sustaining and reignitable. Hydrogen can be injected at the base wall or immediately upstream of the trough. The hydrogen is introduced at low velocity to permit it to be drawn into the corner vortex system and thus experience a long residence time in the combustion region. The igniters can be placed on a skewed back step for angles at least up to 30 deg. without affecting the igniter performance significantly. Certain metals (platinum, copper) act catalytically to improve ignition.

Triboelectrification-Enabled Self-Powered Data Storage.

PubMed

Kuang, Shuang Yang; Zhu, Guang; Wang, Zhong Lin

2018-02-01

Data storage by any means usually requires an electric driving power for writing or reading. A novel approach for self-powered, triboelectrification-enabled data storage (TEDS) is presented. Data are incorporated into a set of metal-based surface patterns. As a probe slides across the patterned surface, triboelectrification between the scanning probe and the patterns produces alternatively varying voltage signal in quasi-square wave. The trough and crest of the quasi-square wave signal are coded as binary bits of "0" and "1," respectively, while the time span of the trough and the crest is associated with the number of bits. The storage of letters and sentences is demonstrated through either square-shaped or disc-shaped surface patterns. Based on experimental data and numerical calculation, the theoretically predicted maximum data storage density could reach as high as 38.2 Gbit in -2 . Demonstration of real-time data retrieval is realized with the assistance of software interface. For the TEDS reported in this work, the measured voltage signal is self-generated as a result of triboelectrification without the reliance on an external power source. This feature brings about not only low power consumption but also a much more simplified structure. Therefore, this work paves a new path to a unique approach of high-density data storage that may have widespread applications.

Concentrating Solar Power Projects - City of Medicine Hat ISCC Project |

Science.gov Websites

trough Turbine Capacity: Net: 1.1 MW Gross: 1.1 MW Status: Operational Start Year: 2014 Do you have more Start Production: November 2014 Cost (approx): 9 $ million Project Type: ISCC Demonstration Participants

Concentrating Solar Power Projects - Abhijeet Solar Project | Concentrating

Science.gov Websites

%) Technology: Parabolic trough Turbine Capacity: Net: 50.0 MW Gross: 50.0 MW Status: Under construction Start Ltd. Company: Ener-t International Ltd. Start Production: 2015 PPA/Tariff Rate: 12.24 Rs per kWh

Concentrating Solar Power Projects - Megha Solar Plant | Concentrating

Science.gov Websites

: Parabolic trough Turbine Capacity: Net: 50.0 MW Gross: 50.0 MW Status: Operational Start Year: 2014 Do you /Planned) Contact(s): Webmaster Solar Break Ground: December 2011 Start Production: November 13, 2014 Cost

Concentrating Solar Power Projects - ISCC Duba 1 | Concentrating Solar

Science.gov Websites

: Parabolic trough Turbine Capacity: Net: 43.0 MW Gross: 43.0 MW Status: Under construction Start Year: 2017 Solar Break Ground: 2016 Start Production: 2017 Participants Developer(s): Saudi Electricity Co. Owner(s

Utility-Scale Solar 2014. An Empirical Analysis of Project Cost, Performance, and Pricing Trends in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bolinger, Mark; Seel, Joachim

2015-09-01

Other than the nine Solar Energy Generation Systems (“SEGS”) parabolic trough projects built in the 1980s, virtually no large-scale or “utility-scale” solar projects – defined here to include any groundmounted photovoltaic (“PV”), concentrating photovoltaic (“CPV”), or concentrating solar thermal power (“CSP”) project larger than 5 MW AC – existed in the United States prior to 2007. By 2012 – just five years later – utility-scale had become the largest sector of the overall PV market in the United States, a distinction that was repeated in both 2013 and 2014 and that is expected to continue for at least the nextmore » few years. Over this same short period, CSP also experienced a bit of a renaissance in the United States, with a number of large new parabolic trough and power tower systems – some including thermal storage – achieving commercial operation. With this critical mass of new utility-scale projects now online and in some cases having operated for a number of years (generating not only electricity, but also empirical data that can be mined), the rapidly growing utility-scale sector is ripe for analysis. This report, the third edition in an ongoing annual series, meets this need through in-depth, annually updated, data-driven analysis of not just installed project costs or prices – i.e., the traditional realm of solar economics analyses – but also operating costs, capacity factors, and power purchase agreement (“PPA”) prices from a large sample of utility-scale solar projects in the United States. Given its current dominance in the market, utility-scale PV also dominates much of this report, though data from CPV and CSP projects are presented where appropriate.« less

Concentrating Solar Power Projects - Morón | Concentrating Solar Power |

Science.gov Websites

, 2018 Project Overview Project Name: Morón Country: Spain Location: Morón de la Frontera (Seville ? Background Technology: Parabolic trough Status: Operational Country: Spain City: Morón de la Frontera Region NREL Morón This page provides information on Morón, a concentrating solar power (CSP) project

α-Oscillations in the monkey sensorimotor network influence discrimination performance by rhythmical inhibition of neuronal spiking.

PubMed

Haegens, Saskia; Nácher, Verónica; Luna, Rogelio; Romo, Ranulfo; Jensen, Ole

2011-11-29

Extensive work in humans using magneto- and electroencephalography strongly suggests that decreased oscillatory α-activity (8-14 Hz) facilitates processing in a given region, whereas increased α-activity serves to actively suppress irrelevant or interfering processing. However, little work has been done to understand how α-activity is linked to neuronal firing. Here, we simultaneously recorded local field potentials and spikes from somatosensory, premotor, and motor regions while a trained monkey performed a vibrotactile discrimination task. In the local field potentials we observed strong activity in the α-band, which decreased in the sensorimotor regions during the discrimination task. This α-power decrease predicted better discrimination performance. Furthermore, the α-oscillations demonstrated a rhythmic relation with the spiking, such that firing was highest at the trough of the α-cycle. Firing rates increased with a decrease in α-power. These findings suggest that α-oscillations exercise a strong inhibitory influence on both spike timing and firing rate. Thus, the pulsed inhibition by α-oscillations plays an important functional role in the extended sensorimotor system.

Concentrating Solar Power Projects - Thai Solar Energy 1 | Concentrating

Science.gov Websites

: Parabolic trough Turbine Capacity: Net: 5.0 MW Gross: 5.0 MW Status: Operational Start Year: 2012 Do you (Expected) Contact(s): Sören Hempel; Yuvaraj Pandian Company: Solarlite GmbH Start Production: January 25

Concentrating Solar Power Projects - Aalborg CSP-Brønderslev CSP with ORC

Science.gov Websites

trough Turbine Capacity: Gross: 16.6 MW Status: Operational Start Year: 2016 Do you have more information Contact(s): Webmaster Solar Key References: Web site Break Ground: April 2016 Start Production: December

Analysis, development and testing of a fixed tilt solar collector employing reversible Vee-Trough reflectors and vacuum tube receivers

NASA Technical Reports Server (NTRS)

Selcuk, M. K.

1979-01-01

The Vee-Trough/Vacuum Tube Collector (VTVTC) aimed to improve the efficiency and reduce the cost of collectors assembled from evacuated tube receivers. The VTVTC was analyzed rigorously and a mathematical model was developed to calculate the optical performance of the vee-trough concentrator and the thermal performance of the evacuated tube receiver. A test bed was constructed to verify the mathematical analyses and compare reflectors made out of glass, Alzak and aluminized GEB Teflon. Tests were run at temperatures ranging from 95 to 180 C during the months of April, May, June, July and August 1977. Vee-trough collector efficiencies of 35-40 per cent were observed at an operating temperature of about 175 C. Test results compared well with the calculated values. Test data covering a complete day are presented for selected dates throughout the test season. Predicted daily useful heat collection and efficiency values are presented for a year's duration at operation temperatures ranging from 65 to 230 C. Estimated collector costs and resulting thermal energy costs are presented. Analytical and experimental results are discussed along with an economic evaluation.

Low-cost small scale parabolic trough collector design for manufacturing and deployment in Africa

NASA Astrophysics Data System (ADS)

Orosz, Matthew; Mathaha, Paul; Tsiu, Anadola; Taele, B. M.; Mabea, Lengeta; Ntee, Marcel; Khakanyo, Makoanyane; Teker, Tamer; Stephens, Jordan; Mueller, Amy

2016-05-01

Concentrating Solar Power is expanding its deployment on the African subcontinent, highlighting the importance of efforts to indigenize manufacturing of this technology to increase local content and therefore local economic benefits of these projects. In this study a design for manufacturing (DFM) exercise was conducted to create a locally produced parabolic trough collector (the G4 PTC). All parts were sourced or fabricated at a production facility in Lesotho, and several examples of the design were prototyped and tested with collaborators in the Government of Lesotho's Appropriate Technology Services division and the National University of Lesotho. Optical and thermal performance was simulated and experimentally validated, and pedagogical pre-commercial versions of the PTC have been distributed to higher education partners in Lesotho and Europe. The cost to produce the PTC is 180 USD/m2 for a locally manufactured heat collection element (HCE) capable of sustaining 250C operation at ~65% efficiency. A version with an imported evacuated HCE can operate at 300°C with 70% efficiency. Economically relevant applications for this locally produced PTC include industrial process heat and distributed generation scenarios where cogeneration is required.

Garvin Heath | NREL

Science.gov Websites

& Impacts Analysis Group in the Strategic Energy Analysis Center. Areas of Expertise Life cycle environmental impacts of energy technologies, including externalities Life cycle assessment Sustainability ;Life Cycle Assessment of a Parabolic Trough Concentrating Solar Power Plant and the Impacts of Key

Concentrating Solar Power Projects - KVK Energy Solar Project |

Science.gov Websites

%) Technology: Parabolic trough Turbine Capacity: Net: 100.0 MW Gross: 100.0 MW Status: Under construction Start °22' 55.0" North, 71°46' 23.0" East Contact(s): SolarPACES Start Production: March 2013 PPA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Binotti, M.; Zhu, G.; Gray, A.

An analytical approach, as an extension of one newly developed method -- First-principle OPTical Intercept Calculation (FirstOPTIC) -- is proposed to treat the geometrical impact of three-dimensional (3-D) effects on parabolic trough optical performance. The mathematical steps of this analytical approach are presented and implemented numerically as part of the suite of FirstOPTIC code. In addition, the new code has been carefully validated against ray-tracing simulation results and available numerical solutions. This new analytical approach to treating 3-D effects will facilitate further understanding and analysis of the optical performance of trough collectors as a function of incidence angle.

A novel portable device to measure the temperature of both the inner and the outer tubes of a parabolic receiver in the field

NASA Astrophysics Data System (ADS)

Hermoso, J. L. Navarro; Espinosa-Rueda, Guillermo; Martinez, Noelia; Heras, Carlos; Osta, Marta

2016-05-01

The performance of parabolic trough (PT) receiver tubes (RT) has a direct impact on Solar Thermal Energy (STE) plant production. As a result, one major need of operation and maintenance (O&M) in STE plants is to monitor the state of the receiver tube as a key element in the solar field. However the lack of specific devices so far has limited the proper evaluation of operating receiver tubés thermal performance. As a consequence non-accurate approximations have been accepted until now using infrared thermal images of the glass outer tube. In order to fulfill this need, Abengoa has developed a unique portable device for evaluating the thermal performance and vacuum state of parabolic trough receiver tubes placed in the field. The novel device described in this paper, simultaneously provides the temperature of both the inner steel tube and the outer glass tube enabling a check on manufacturers specifications. The on-field evaluation of any receiver tube at any operating temperature has become possible thanks to this new measuring device. The features and usability of this new measurement system as a workable portable device in operating solar fields provide a very useful tool for all companies in the sector contributing to technology progress. The originality of the device, patent pending P201431969, is not limited to the CSP sector, also having scientific significance in the general measuring instruments field. This paper presents the work carried out to develop and validate the device, also detailing its functioning properties and including the excellent results obtained in the laboratory to determine its accuracy and standard deviation. This information was validated with data collected by O&M teams using this instrument in a commercial CSP plant. The relevance of the device has been evidenced by evaluating a wide sample of RT and the results are discussed in this paper. Finally, all the on field collected data is used to demonstrate the high impact that using this unique portable device will have on a parabolic trough solar power plant.

Use of rapid prototyping drill template for the expansive open door laminoplasty: A cadaveric study.

PubMed

Rong, Xin; Wang, Beiyu; Chen, Hua; Ding, Chen; Deng, Yuxiao; Ma, Lipeng; Ma, Yanzhao; Liu, Hao

2016-11-01

Trough preparation is a technically demanding yet critical procedure for successful expansive open door laminoplasty (EOLP), requiring both proper position and appropriate bone removal. We aimed to use the specific rapid prototyping drill template to achieve such requirement. The 3D model of the cadaveric cervical spine was reconstructed using the Mimics 17.0 and Geomagic Studio 12.0 software. The drilling template was designed in the 3-Matic software. The trough position was simulated at the medial margin of the facet joint. Two holders were designed on both sides. On the open side, the holder would just allow the drill penetrate the ventral cortex of the lamina. On the hinge side, the holder was designed to keep the ventral cortex of the lamina intact. One orthopedic resident performed the surgery using the rapid prototyping drill template on four cadavers (template group). A control group of four cadavers were operated upon without the use of the template. The deviation of the final trough position from the simulated trough position was 0.18mm±0.51mm in the template group. All the troughs in the template group and 40% of the troughs in the control group were at the medial side of the facet joint. The complete hinge fracture rate was 5% in the template group, significantly lower than that (55%) in the control group (P=0.01). The rapid prototyping drill template could help the surgeon accomplish proper trough position and appropriate bone removal in EOLP on the cadaveric cervical spine. Copyright © 2016 Elsevier B.V. All rights reserved.

Evidence to Support Monitoring of Vedolizumab Trough Concentrations in Patients With Inflammatory Bowel Diseases.

PubMed

Dreesen, Erwin; Verstockt, Bram; Bian, Sumin; de Bruyn, Magali; Compernolle, Griet; Tops, Sophie; Noman, Maja; Van Assche, Gert; Ferrante, Marc; Gils, Ann; Vermeire, Séverine

2018-04-25

Trough concentrations of vedolizumab were found to correlate with clinical response in phase 3 studies of patients with ulcerative colitis (UC) or Crohn's disease (CD). Nevertheless, there are no solid data to support monitoring of vedolizumab trough concentrations in treated patients. We investigated the correlation between vedolizumab exposure and response in a real-world population and aimed to identify patient factors that affect exposure and response. We performed a retrospective cohort study of 179 consecutive patients (66 with UC and 113 with CD) who began vedolizumab therapy from September 1, 2015, through October 1, 2016, at University Hospitals Leuven, Belgium. Serum concentrations of vedolizumab were measured before all infusions up to week 30. Effectiveness endpoints included endoscopic healing (UC, Mayo endoscopic sub-score ≤1; CD, absence of ulcers), clinical response (physicians' global assessment), and biologic response or remission (based on level of C-reactive protein) and were assessed at week 14 (for patients with UC) and week 22 (for patients with CD). A stepwise forward addition-backward elimination modeling approach was performed to identify factors independently associated with vedolizumab exposure and response. Vedolizumab trough concentrations >30.0 μg/mL at week 2, >24.0 μg/mL at week 6, and >14.0 μg/mL during maintenance therapy associated with a higher probability of attaining the effectiveness endpoints for patients with UC or CD (P < .05). Higher body mass and more severe disease (based on high level of C-reactive protein and low level of albumin and/or hemoglobin) at the start of vedolizumab therapy associated with lower trough concentrations of vedolizumab over the 30-week period and a lower probability of achieving mucosal healing (P < .05). Mucosal healing was achieved in significantly more patients with UC than patients with CD, even though a diagnosis of UC was not an independent predictor of higher vedolizumab trough concentrations. In a retrospective study of 179 patients with CD or UC, we observed a correlation between vedolizumab exposure and response. These findings support monitoring of vedolizumab trough concentrations to predict patients' outcome. Copyright © 2018 AGA Institute. Published by Elsevier Inc. All rights reserved.

Forecasting Financial Extremes: A Network Degree Measure of Super-Exponential Growth.

PubMed

Yan, Wanfeng; van Tuyll van Serooskerken, Edgar

2015-01-01

Investors in stock market are usually greedy during bull markets and scared during bear markets. The greed or fear spreads across investors quickly. This is known as the herding effect, and often leads to a fast movement of stock prices. During such market regimes, stock prices change at a super-exponential rate and are normally followed by a trend reversal that corrects the previous overreaction. In this paper, we construct an indicator to measure the magnitude of the super-exponential growth of stock prices, by measuring the degree of the price network, generated from the price time series. Twelve major international stock indices have been investigated. Error diagram tests show that this new indicator has strong predictive power for financial extremes, both peaks and troughs. By varying the parameters used to construct the error diagram, we show the predictive power is very robust. The new indicator has a better performance than the LPPL pattern recognition indicator.

Rheology and microrheology of materials at the air-water interface

NASA Astrophysics Data System (ADS)

Walder, Robert Benjamin

2008-10-01

The study of materials at the air-water interface is an important area of research in soft condensed matter physics. Films at the air-water interface have been a system of interest to physics, chemistry and biology for the last 20 years. The unique properties of these surface films provide ideal models for 2-d films, surface chemistry and provide a platform for creating 2 dimensional analogue materials to cellular membranes. Measurements of the surface rheology of cross-linked F-actin networks associated with a lipid monolayer at the air-water interface of a Langmuir monolayer have been performed. The rheological measurements are made using a Couette cell. These data demonstrate that the network has a finite elastic modulus that grows as a function of the cross-linking concentration. We also note that under steady-state flow the system behaves as a power law fluid in which the effective viscosity decreases with imposed shear. A Langmuir monolayer trough that is equipped for simultaneous microrheology and standard rheology measurements has been constructed. The central elements are the trough itself with a full range of optical tools accessing the air-water interface from below the trough and a portable knife-edge torsion pendulum that can access the interface from above. The ability to simultaneously measure the mechanical response of Langmuir monolayers on very different length scales is an important step for our understanding of the mechanical response of two-dimensional viscoelastic networks. The optical tweezer microrheometer is used to study the micromechanical properties of Langmuir monolayers. Microrheology measurements are made a variety of surface pressures that correspond to different ordered phases of the monolayer. The complex shear modulus shows an order of magnitude increase for the liquid condensed phase of DPPC compared to the liquid expanded phase.

Laser welding on trough panel: 3D body part

NASA Astrophysics Data System (ADS)

Shirai, Masato; Hisano, Hirohiko

2003-03-01

Laser welding for automotive bodies has been introduced mainly by European car manufacturers since more than 10 years ago. Their purposes of laser welding introduction were mainly vehicle performance improvement and lightweight. And laser welding was applied to limited portion where shapes of panels are simple and easy to fit welded flanges. Toyota also has introduced laser welding onto 3 dimensional parts named trough panel since 1999. Our purpose of the introduction was common use of equipment. Trough panel has a complex shape and different shapes in each car type. In order to realize common use of welding equipment, we introduced parts locating equipment which had unique, small & simple jigs fo each car type and NC (Numerical Controlled) locators and air-cooled small laser head developed by ourselves to the trough welding process. Laser welding replaced spot welding and was applied linearly like stitches. Length of laser welding was determined according to comparison with statistic tensile strength and fatigue strength of spot welding.

Plasma trough concentrations of darunavir/ritonavir and raltegravir in older patients with HIV-1 infection.

PubMed

Calza, L; Colangeli, V; Magistrelli, E; Bussini, L; Conti, M; Ramazzotti, E; Mancini, R; Viale, P

2017-08-01

The aim of the study was to assess plasma concentrations of darunavir/ritonavir and raltegravir in older patients compared with younger patients with HIV-1 infection. In this observational, open-label study, adult HIV-infected out-patients aged ≤ 40 years (younger patients) or ≥ 60 years (older patients) and treated with tenofovir/emtricitabine plus darunavir/ritonavir (800/100 mg daily) or raltegravir (400 mg twice daily) were asked to participate. The trough concentrations (C trough ) of darunavir/ritonavir and raltegravir were assessed at steady state using a validated high-performance liquid chromatography (HPLC)-tandem mass spectrometry method. A total of 88 HIV-positive patients were enrolled in the study. Forty-six patients were treated with darunavir/ritonavir, and 42 with raltegravir. The geometric mean plasma C trough (coefficient of variation) of raltegravir was comparable between the 19 older and 23 younger subjects: 106 ng/mL (151%) and 94 ng/mL (129%), respectively [geometric mean ratio (GMR) 0.85; 95% confidence interval (CI) 0.71-1.57; P = 0.087]. In contrast, the geometric mean plasma C trough of darunavir was significantly higher among the 21 older patients [2209 ng/mL (139%)] than among the 25 younger patients [1876 ng/mL (162%); GMR 1.56; 95% CI: 1.22-1.88; P = 0.004]. Similarly, the geometric mean C trough of ritonavir was significantly higher among older than among younger individuals. The mean plasma C trough of darunavir and ritonavir was significantly higher in older patients than in younger patients with HIV-1 infection, while the mean plasma level of raltegravir was comparable in the two groups. However, both regimens showed good tolerability in both younger and older subjects. © 2017 British HIV Association.

Healthcare-associated Staphylococcus aureus bacteremia in children: Evidence for reverse vancomycin creep and impact of vancomycin trough levels on outcome

PubMed Central

McNeil, J Chase; Kok, Eric Y; Forbes, Andrea; Lamberth, Linda; Hulten, Kristina G; Vallejo, Jesus G; Mason, Edward O; Kaplan, Sheldon L

2015-01-01

Introduction Elevated vancomycin MICs in S. aureus have been associated with worse clinical outcomes in adults. For invasive MRSA infections in adults, the IDSA recommends targeting vancomycin serum trough concentrations between 15–20 μg/ml. We evaluated trends in vancomycin MICs from healthcare-associated S. aureus bacteremia isolates in children in addition to correlating vancomycin serum trough levels with clinical outcomes. Methods Patients and isolates were identified from a prospective S. aureus surveillance study at Texas Children's Hospital (TCH). Healthcare-associated S. aureus bacteremia isolates from 2003–2013 were selected. Vancomycin MICs by E-test were determined and medical records were reviewed. Acute kidney injury (AKI) was defined as doubling of the baseline serum creatinine. Results 341 isolates met inclusion criteria. We observed a reverse vancomycin creep among MRSA isolates in the study period with a decline in the proportion of isolates with vancomycin MIC ≥ 2 μg/ml (from 32.7% to 5.6%, p<0.001). However, the proportion of MSSA isolates with MIC ≥ 2 μg/ml increased (from 2.9% to 9%, p=0.04). Among patients who had vancomycin troughs performed, there was no difference in duration of bacteremia or fever with vancomycin trough >15 μg/ml vs. < 15 μg/ml. A vancomycin trough > 15 μg/ml was, however, an independent risk factor for AKI. Conclusions Vancomycin MICs are shifting among healthcare-associated S. aureus bacteremia isolates with significant differences between MRSA and MSSA at TCH. Higher vancomycin troughs did not improve outcomes in pediatric healthcare-associated S. aureus bacteremia but were associated with increased nephrotoxicity. Further studies are needed to better understand optimal management of children with S. aureus bacteremia. PMID:26646549

Experimental evaluation of a fixed collector employing vee-trough concentrator and vacuum tube receivers

NASA Technical Reports Server (NTRS)

Selcuk, M. K.

1977-01-01

A test bed for experimental evaluation of a fixed solar collector which combines an evacuated glass tube solar receiver with a flat plate/black chrome plated copper absorber and an asymmetric vee-trough concentrator was designed and constructed. Earlier predictions of thermal performance were compared with test data acquired for a bare vacuum tube receiver; and receiver tubes with Alzak aluminum, aluminized FEP Teflon film laminated sheet metal and second surface ordinary mirror reflectors. Test results and system economics as well as objectives of an ongoing program to obtain long-term performance data are discussed.

Optimizing the Utility Power of a Geothermal Power Plant using Variable Frequency Drive (VFD) (Case Study: Sibayak Geothermal Power Plant)

NASA Astrophysics Data System (ADS)

Sinaga, R. H. M.; Manik, Y.

2018-03-01

Sibayak Geothermal Power Plant (SGPP) is one of the plants being developed by Pertamina Geothermal Energy (PGE) at the upstream phase. At the downstream phase, State - owned Electricity Company (PLN) through PT. Dizamatra Powerindo is the developer. The gross capacity of the power plant is 13.3 MW, consisting 1 unit of Monoblock (2 MW) developed by PGE and 2 units (2×5.65 MW) operated through Energy Sales Contract by PLN. During the development phase of a geothermal power plant, there is a chance to reduce the utility power in order to increase the overall plant efficiency. Reducing the utility power can be attempted by utilizing the wet bulb temperature fluctuation. In this study, a modeling process is developed by using Engineering Equation Solver (EES) software version 9.430. The possibility of energy saving is indicated by condenser pressure changes as a result of wet bulb temperature fluctuation. The result of this study indicates that the change of condenser pressure is about 50.8% on the constant liquid/gas (L/G) condition of the wet bulb temperature of 15°C to 25°C. Further result indicates that in this power plant, Cooling Tower Fan (CTF) is the facility that has the greatest utility load, followed by Hot Well Pump (HWP). The saving of the greatest utility load is applied trough Variable Frequency Drive (VFD) instrumentation. The result of this modeling has been validated by actual operations data (log sheet). The developed model has also been reviewed trough Specific Steam Consumption (SSC), resulting that constant L/G condition allows the optimum condition on of the wet bulb temperature of 15°C to 25°C.

Concentrating Solar Power Projects - Colorado Integrated Solar Project |

Science.gov Websites

Energy's Cameo Station's Unit 2 (approximately 2 MWe equivalent) in order to decrease the overall MW Status: Currently Non-Operational Start Year: 2010 Do you have more information, corrections, or comments? Background Technology: Parabolic trough Status: Currently Non-Operational Country: United States

Concentrating Solar Power Projects in United Arab Emirates | Concentrating

Science.gov Websites

Emirates are listed belowâ€"alphabetical by project name. You can browse a project profile by clicking on the project name. DEWA CSP Tower Project DEWA CSP Trough Project Shams 1(Shams 1)

Effect of topography on wind turbine power and load fluctuations

NASA Astrophysics Data System (ADS)

Santoni, Christian; Ciri, Umberto; Leonardi, Stefano

2015-11-01

Onshore wind turbines produce more than 17 GW in the US, which constitutes 4 . 4 % of all the energy produced. Sites selection is mostly determined by the atmospheric conditions and the topographical characteristics of the region. While the effect of the atmospheric boundary layer had been widely studied, less attention has been given to the effect of the topography on the wind turbine aerodynamics. To address how the topography affects the flow, Large Eddy Simulations of the flow over a wind turbine placed over wavy wall are performed. The wavelength of the wavy terrain, λ, is 1 . 7 D where D is the turbine rotor diameter. Two different values of the height of the wavy wall, a / D = 0 . 05 and a / D = 0 . 10 have been considered. In addition, two positions of the turbine with respect to the wavy wall had been studied, on the crest and trough of the wavy wall and compared with a wind turbine over a flat wall. For the turbine located at the crest, the pressure gradient due to the wavy wall caused a recirculation behind the wind tower 2 . 5 D larger than that of the smooth wall. When placed at the trough of the wavy terrain, the favorable pressure gradient increases the wake velocity near the wall and promotes entrainment into the turbine wake. Numerical simulations were performed on XSEDE TACC, Grant CTS070066. This work was supported by the NSF, grant IIA-1243482 (WINDINSPIRE).

Rinse trough with improved flow

DOEpatents

O'Hern, Timothy J.; Grasser, Thomas W.

1998-01-01

Novel rinse troughs accomplish thorough uniform rinsing. The troughs are suitable for one or more essentially planar objects having substantially the same shape. The troughs ensure that each surface is rinsed uniformly. The new troughs provide uniform rinse fluid flow over the objects' surfaces to accomplish a more thorough rinse than prior art troughs.

Rinse trough with improved flow

DOEpatents

O`Hern, T.J.; Grasser, T.W.

1998-08-11

Novel rinse troughs accomplish thorough uniform rinsing. The troughs are suitable for one or more essentially planar objects having substantially the same shape. The troughs ensure that each surface is rinsed uniformly. The new troughs provide uniform rinse fluid flow over the objects` surfaces to accomplish a more thorough rinse than prior art troughs. 5 figs.

Corrugated pipe adhesive applicator apparatus

DOEpatents

Shirey, R.A.

1983-06-14

Apparatus for coating selected portions of the troughs of a corrugated pipe with an adhesive includes a support disposed within the pipe with a reservoir containing the adhesive disposed on the support. A pump, including a spout, is utilized for supplying the adhesive from the reservoir to a trough of the pipe. A rotatable applicator is supported on the support and contacts the trough of the pipe. The applicator itself is sized so as to fit within the trough, and contacts the adhesive in the trough and spreads the adhesive in the trough upon rotation. A trough shield, supported by the support and disposed in the path of rotation of the applicator, is utilized to prevent the applicator from contacting selected portions of the trough. A locator head is also disposed on the support and provides a way for aligning the spout, the applicator, and the trough shield with the trough. 4 figs.

Parabolic trough receiver heat loss and optical efficiency round robin 2015/2016

NASA Astrophysics Data System (ADS)

Pernpeintner, Johannes; Schiricke, Björn; Sallaberry, Fabienne; de Jalón, Alberto García; López-Martín, Rafael; Valenzuela, Loreto; de Luca, Antonio; Georg, Andreas

2017-06-01

A round robin for parabolic trough receiver heat loss and optical efficiency in the laboratory was performed between five institutions using five receivers in 2015/2016. Heat loss testing was performed at three cartridge heater test benches and one Joule heating test bench in the temperature range between 100 °C and 550 °C. Optical efficiency testing was performed with two spectrometric test bench and one calorimetric test bench. Heat loss testing results showed standard deviations at the order of 6% to 12 % for most temperatures and receivers and a standard deviation of 17 % for one receiver at 100 °C. Optical efficiency is presented normalized for laboratories showing standard deviations of 0.3 % to 1.3 % depending on the receiver.

Concentrating Solar Power Projects - Manchasol-2 | Concentrating Solar

Science.gov Websites

Juan (Ciudad Real) Owner(s): ACS/Cobra Group (100%) Technology: Parabolic trough Turbine Capacity: Net : ACS/Cobra Group Break Ground: May 2009 Start Production: April 2011 Construction Job-Years: 600 Annual : Commercial Participants Developer(s): ACS/Cobra Group Owner(s) (%): ACS/Cobra Group (100%) EPC Contractor

Concentrating Solar Power Projects - Manchasol-1 | Concentrating Solar

Science.gov Websites

Juan (Ciudad Real) Owner(s): ACS/Cobra Group (100%) Technology: Parabolic trough Turbine Capacity: Net : ACS/Cobra Group Break Ground: October 2008 Start Production: January 2011 Construction Job-Years: 600 : Commercial Participants Developer(s): ACS/Cobra Group Owner(s) (%): ACS/Cobra Group (100%) EPC Contractor

Field test of thermoelectric generator using parabolic trough solar concentrator for power generation

NASA Astrophysics Data System (ADS)

Viña, Rommel R.; Alagao, Feliciano B.

2018-03-01

A 2.4587 square meter effective area cylindrical parabolic solar concentrator was fabricated. The trough concentrator is a 4-ft by 8-ft metal sheet with solar mirror film adhered on it and it is laid on a frame with steel tubes bent in a shape of a parabola. On the focal region of the parabolic trough is the 1.22-m by 0.10-m absorber plate made of copper and coated flat black. This plate served as high temperature reservoir of the eight equally spaced TEC1-12710T125 thermoelectric modules. On the cold side of the modules is a 2.5-in. by 1-in. rectangular aluminum tube with coolant flowing inside. The coolant loop included a direct contact cooling tower which maintained the module cold side assembly inlet temperature of about 28°C. Collector temperature was also kept below the 125°C module maximum operating temperature by controlling the effective area. This was accomplished by adjusting the reflector covering. Using a dummy load and with 8 modules in series, tests results indicated current readings up to 179.4 mA with a voltage of 10.6 VDC and 27% of reflector area or voltage reading up to 12.7 VDC with a current of 165 mA. A steady voltage of 12 VDC was achieved with the use of a voltage regulator. A voltage above 12 VDC will be required to charge a storage battery. Overall results showed the potential of thermoelectric generator (TEG) in combination with solar energy in power generation.

PVMirrors: Hybrid PV/CSP collectors that enable lower LCOEs

NASA Astrophysics Data System (ADS)

Fisher, Kate; Yu, Zhengshan Jason; Striling, Rob; Holman, Zachary

2017-06-01

The primary challenge with concentrating solar power (CSP) is that the conversion efficiency is low—and the cost high—compared to that of photovoltaics (PV), and the primary challenge with PV is that the energy generated cannot be stored cost effectively. We introduce a technology that hybridizes CSP and PV, resulting in power plants with high energy conversion efficiency and affordable storage. This is accomplished by replacing silvered troughs (or heliostat facets) with "PVMirrors" that and direct photons of each wavelength to the converter (PV or thermal) that may best use them. A PVMirror looks like a curved PV module that includes a spectrum-splitting dichroic mirror film; this film, which is the heart of the technology, transmits near-infrared light to the underlying silicon PV cells while reflecting both longer and shorter wavelengths to a thermal absorber tube. This paper investigates the optical performance of dichroic mirror film, the specularity of PVMirrors, and the anticipated levelized cost of energy (LCOE) from a PVMirror power plant. PVMirrors are found to decrease LCOE by more than 15% relative to CSP while retaining full dispatchability.

Survey mirrors and lenses and their required surface accuracy. Volume 2. Concentrator optical performance software (COPS) user's manual. Final report for September 15, 1978-December 1, 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-01-01

The mathematical modeling of 11 different concentrating collectors is documented and instructions are given for use of the computer code. The 11 concentrators modeled are: faceted mirror concentration; fixed mirror, two-axis tracking receiver; parabolic trough collector; linear Fresnel; incremental reflector; inflated cylindrical concentrator; CPC-involute reflector with evacuated receiver; CPC-parabolic/involute reflector; V trough collectors, imaging collapsing concentrator; and parabolic dish collector. (MHR)

Clinical results of a surgical technique using endobuttons for complete tendon tear of pectoralis major muscle: report of five cases

PubMed Central

2011-01-01

Background We herein describe a surgical technique for the repair of complete tear of the pectoralis major (PM) tendon using endobuttons to strengthen initial fixation. Methods Five male patients (3 judo players, 1 martial arts player, and 1 body builder) were treated within 2 weeks of sustaining complete tear of the PM tendon. Average age at surgery and follow-up period were 28.4 years (range, 23-33) and 28.8 months (range, 24-36). A rectangular bone trough (about 1 × 4 cm) was created on the humerus at the insertion of the distal PM tendon. The tendon stump was introduced into this trough, and fixed to the reverse side of the humeral cortex using endobuttons and non-absorbable suture. Clinical assessment of re-tear was examined by MRI. Shoulder range of motion (ROM), outcome of treatment, and isometric power were measured at final follow-up. Results There were no clinical re-tears, and MRI findings also showed continuity of the PM tendon in all cases at final follow-up. Average ROM did not differ significantly between the affected and unaffected shoulders. The clinical outcomes at final follow-up were excellent (4/5 cases) or good (1/5). In addition, postoperative isometric power in horizontal flexion of the affected shoulder showed complete recovery when compared with the unaffected side. Conclusions Satisfactory outcomes could be obtained when surgery using the endobutton technique was performed within 2 weeks after complete tear of the PM tendon. Therefore, our new technique appears promising as a useful method to treat complete tear of the PM tendon. PMID:21955511

Healthcare-associated Staphylococcus aureus Bacteremia in Children: Evidence for Reverse Vancomycin Creep and Impact of Vancomycin Trough Values on Outcome.

PubMed

McNeil, J Chase; Kok, Eric Y; Forbes, Andrea R; Lamberth, Linda; Hulten, Kristina G; Vallejo, Jesus G; Mason, Edward O; Kaplan, Sheldon L

2016-03-01

Elevated vancomycin minimum inhibitory concentrations (MICs) in Staphylococcus aureus have been associated with worse clinical outcomes in adults. For invasive meticillin-resistant S. aureus (MRSA) infections in adults, the Infectious Diseases Society of America recommends targeting vancomycin serum trough concentrations between 15 and 20 μg/mL. We evaluated trends in vancomycin MICs from healthcare-associated (HCA) S. aureus bacteremia isolates in children in addition to correlating vancomycin serum trough levels with clinical outcomes. Patients and isolates were identified from a prospective S. aureus surveillance study at Texas Children's Hospital (TCH). HCA S. aureus bacteremia isolates from 2003 to 2013 were selected. Vancomycin MICs by E-test were determined and medical records were reviewed. Acute kidney injury (AKI) was defined as doubling of the baseline serum creatinine. Three hundred forty-one isolates met inclusion criteria. We observed a reverse vancomycin creep among MRSA isolates in the study period with a decline in the proportion of isolates with vancomycin MIC ≥ 2 μg/mL (from 32.7% to 5.6%; P < 0.001). However, the proportion of MSSA isolates with MIC ≥ 2 μg/mL increased (from 2.9% to 9%; P = 0.04). Among patients who had vancomycin troughs performed, there was no difference in duration of bacteremia or fever with vancomycin trough >15 versus <15 μg/mL. A vancomycin trough >15 μg/mL was, however, an independent risk factor for AKI. Vancomycin MICs are shifting among HCA S. aureus bacteremia isolates with significant differences between MRSA and MSSA at TCH. Higher vancomycin troughs did not improve outcomes in pediatric HCA S. aureus bacteremia but were associated with increased nephrotoxicity. Further studies are needed to better understand optimal management of children with S. aureus bacteremia.

A trough for improved SFG spectroscopy of lipid monolayers.

PubMed

Franz, Johannes; van Zadel, Marc-Jan; Weidner, Tobias

2017-05-01

Lipid monolayers are indispensable model systems for biological membranes. The main advantage over bilayer model systems is that the surface pressure within the layer can be directly and reliably controlled. The sensitive interplay between surface pressure and temperature determines the molecular order within a model membrane and consequently determines the membrane phase behavior. The lipid phase is of crucial importance for a range of membrane functions such as protein interactions and membrane permeability. A very reliable method to probe the structure of lipid monolayers is sum frequency generation (SFG) vibrational spectroscopy. Not only is SFG extremely surface sensitive but it can also directly access critical parameters such as lipid order and orientation, and it can provide valuable information about protein interactions along with interfacial hydration. However, recent studies have shown that temperature gradients caused by high power laser beams perturb the lipid layers and potentially obscure the spectroscopic results. Here we demonstrate how the local heating problem can be effectively reduced by spatially distributing the laser pulses on the sample surface using a translating Langmuir trough for SFG experiments at lipid monolayers. The efficiency of the trough is illustrated by the detection of enhanced molecular order due to reduced heat load.

A trough for improved SFG spectroscopy of lipid monolayers

NASA Astrophysics Data System (ADS)

Franz, Johannes; van Zadel, Marc-Jan; Weidner, Tobias

2017-05-01

Lipid monolayers are indispensable model systems for biological membranes. The main advantage over bilayer model systems is that the surface pressure within the layer can be directly and reliably controlled. The sensitive interplay between surface pressure and temperature determines the molecular order within a model membrane and consequently determines the membrane phase behavior. The lipid phase is of crucial importance for a range of membrane functions such as protein interactions and membrane permeability. A very reliable method to probe the structure of lipid monolayers is sum frequency generation (SFG) vibrational spectroscopy. Not only is SFG extremely surface sensitive but it can also directly access critical parameters such as lipid order and orientation, and it can provide valuable information about protein interactions along with interfacial hydration. However, recent studies have shown that temperature gradients caused by high power laser beams perturb the lipid layers and potentially obscure the spectroscopic results. Here we demonstrate how the local heating problem can be effectively reduced by spatially distributing the laser pulses on the sample surface using a translating Langmuir trough for SFG experiments at lipid monolayers. The efficiency of the trough is illustrated by the detection of enhanced molecular order due to reduced heat load.

Inhomogeneous Crustal Structure of the Rifting in the Okinawa Trough, a Backarc Basin West of Kyushu, Japan, Deduced from Seismic Reflection and Refraction Data

NASA Astrophysics Data System (ADS)

Nishizawa, A.; Kaneda, K.; Oikawa, M.; Horiuchi, D.; Fujioka, Y.; Okada, C.

2017-12-01

Several depressions found under the thick sediments in the East China Sea shelf have been considered as failed rift basins. Their formation age becomes progressively younger from NW to SE and the youngest rift basin is the Okinawa Trough, an active backarc basin of the Ryukyu (Nansei-Shoto) arc-trench system, to the southwest of Kyusyu, Japan. Its rifting is in progress and related hydrothermal activity is present in the trough. The knowledge of the crustal structure of the trough is fundamental to understand the current active tectonics and predict the future of the trough. We, Japan Coast Guard, have conducted extensive seismic reflection and refraction surveys in the Ryukyu region since 2008 and compiled the seismic structures of the Okinawa Trough. We will show the crustal structures along seven along-trough and ten across-trough seismic survey lines. The P-wave velocity models beneath the Okinawa Trough generally show a thinned continental/island arc crust consisting of upper, middle, and lower crusts. Moho depths below the trough were estimated mainly from Moho reflection (PmP) travel times. The crustal thickness of the trough is thinner than those of the East China Sea shelf and of the Ryukyu Islands. The depth of the Moho below the trough decreases from over 30 km in the north to about 13 km in the south, indicating a difference in degree of the rifting process. The position of the shallowest Moho along the across-trough lines in the northern trough does not necessarily correspond to the center of the trough defined as the deepest water depth, but it corresponds to the transition area between the East China Sea shelf and the Okinawa Trough. An M7.1 earthquake occurred at the transition area on Nov. 14, 2015 (JST) and many aftershocks were observed along the transition. This seismic activity demonstrated that the area is under rifting tectonics in the present.

Directed flow fluid rinse trough

DOEpatents

Kempka, Steven N.; Walters, Robert N.

1996-01-01

Novel rinse troughs accomplish thorough uniform rinsing. The tanks are suitable for one or more essentially planar items having substantially the same shape. The troughs ensure that each surface is rinsed uniformly. The new troughs also require less rinse fluid to accomplish a thorough rinse than prior art troughs.

Investigations on the Aerodynamic Characteristics and Blade Excitations of the Radial Turbine with Pulsating Inlet Flow

NASA Astrophysics Data System (ADS)

Liu, Yixiong; Yang, Ce; Yang, Dengfeng; Zhang, Rui

2016-04-01

The aerodynamic performance, detailed unsteady flow and time-based excitations acting on blade surfaces of a radial flow turbine have been investigated with pulsation flow condition. The results show that the turbine instantaneous performance under pulsation flow condition deviates from the quasi-steady value significantly and forms obvious hysteretic loops around the quasi-steady conditions. The detailed analysis of unsteady flow shows that the characteristic of pulsation flow field in radial turbine is highly influenced by the pulsation inlet condition. The blade torque, power and loading fluctuate with the inlet pulsation wave in a pulse period. For the blade excitations, the maximum and the minimum blade excitations conform to the wave crest and wave trough of the inlet pulsation, respectively, in time-based scale. And toward blade chord direction, the maximum loading distributes along the blade leading edge until 20% chord position and decreases from the leading to trailing edge.

Directed flow fluid rinse trough

DOEpatents

Kempka, S.N.; Walters, R.N.

1996-07-02

Novel rinse troughs accomplish thorough uniform rinsing. The tanks are suitable for one or more essentially planar items having substantially the same shape. The troughs ensure that each surface is rinsed uniformly. The new troughs also require less rinse fluid to accomplish a thorough rinse than prior art troughs. 9 figs.

A Low-Power and Portable Biomedical Device for Respiratory Monitoring with a Stable Power Source

PubMed Central

Yang, Jiachen; Chen, Bobo; Zhou, Jianxiong; Lv, Zhihan

2015-01-01

Continuous respiratory monitoring is an important tool for clinical monitoring. Associated with the development of biomedical technology, it has become more and more important, especially in the measuring of gas flow and CO2 concentration, which can reflect the status of the patient. In this paper, a new type of biomedical device is presented, which uses low-power sensors with a piezoresistive silicon differential pressure sensor to measure gas flow and with a pyroelectric sensor to measure CO2 concentration simultaneously. For the portability of the biomedical device, the sensors and low-power measurement circuits are integrated together, and the airway tube also needs to be miniaturized. Circuits are designed to ensure the stability of the power source and to filter out the existing noise. Modulation technology is used to eliminate the fluctuations at the trough of the waveform of the CO2 concentration signal. Statistical analysis with the coefficient of variation was performed to find out the optimal driving voltage of the pressure transducer. Through targeted experiments, the biomedical device showed a high accuracy, with a measuring precision of 0.23 mmHg, and it worked continuously and stably, thus realizing the real-time monitoring of the status of patients. PMID:26270665

Prospective Evaluation of a Model-Based Dosing Regimen for Amikacin in Preterm and Term Neonates in Clinical Practice

PubMed Central

De Cock, R. F. W.; Allegaert, K.; Vanhaesebrouck, S.; Danhof, M.; Knibbe, C. A. J.

2015-01-01

Based on a previously derived population pharmacokinetic model, a novel neonatal amikacin dosing regimen was developed. The aim of the current study was to prospectively evaluate this dosing regimen. First, early (before and after second dose) therapeutic drug monitoring (TDM) observations were evaluated for achieving target trough (<3 mg/liter) and peak (>24 mg/liter) levels. Second, all observed TDM concentrations were compared with model-predicted concentrations, whereby the results of a normalized prediction distribution error (NPDE) were considered. Subsequently, Monte Carlo simulations were performed. Finally, remaining causes limiting amikacin predictability (i.e., prescription errors and disease characteristics of outliers) were explored. In 579 neonates (median birth body weight, 2,285 [range, 420 to 4,850] g; postnatal age 2 days [range, 1 to 30 days]; gestational age, 34 weeks [range, 24 to 41 weeks]), 90.5% of the observed early peak levels reached 24 mg/liter, and 60.2% of the trough levels were <3 mg/liter (93.4% ≤5 mg/liter). Observations were accurately predicted by the model without bias, which was confirmed by the NPDE. Monte Carlo simulations showed that peak concentrations of >24 mg/liter were reached at steady state in almost all patients. Trough values of <3 mg/liter at steady state were documented in 78% to 100% and 45% to 96% of simulated cases with and without ibuprofen coadministration, respectively; suboptimal trough levels were found in patients with postnatal age <14 days and current weight of >2,000 g. Prospective evaluation of a model-based neonatal amikacin dosing regimen resulted in optimized peak and trough concentrations in almost all patients. Slightly adapted dosing for patient subgroups with suboptimal trough levels was proposed. This model-based approach improves neonatal dosing individualization. PMID:26248375

Patient-reported non-adherence and immunosuppressant trough levels are associated with rejection after renal transplantation.

PubMed

Scheel, Jennifer; Reber, Sandra; Stoessel, Lisa; Waldmann, Elisabeth; Jank, Sabine; Eckardt, Kai-Uwe; Grundmann, Franziska; Vitinius, Frank; de Zwaan, Martina; Bertram, Anna; Erim, Yesim

2017-03-29

Different measures of non-adherence to immunosuppressant (IS) medication have been found to be associated with rejection episodes after successful transplantation. The aim of the current study was to investigate whether graft rejection after renal transplantation is associated with patient-reported IS medication non-adherence and IS trough level variables (IS trough level variability and percentage of sub-therapeutic IS trough levels). Patient-reported non-adherence, IS trough level variability, percentage of sub-therapeutic IS trough levels, and acute biopsy-proven late allograft rejections were assessed in 267 adult renal transplant recipients who were ≥12 months post-transplantation. The rate of rejection was 13.5%. IS trough level variability, percentage of sub-therapeutic IS trough levels as well as patient-reported non-adherence were all significantly and positively associated with rejection, but not with each other. Logistic regression analyses revealed that only the percentage of sub-therapeutic IS trough levels and age at transplantation remained significantly associated with rejection. Particularly, the percentage of sub-therapeutic IS trough levels is associated with acute rejections after kidney transplantation whereas IS trough level variability and patient-reported non-adherence seem to be of subordinate importance. Patient-reported non-adherence and IS trough level variables were not correlated; thus, non-adherence should always be measured in a multi-methodological approach. Further research concerning the best combination of non-adherence measures is needed.

Sensor for measuring hydrogen partial pressure in parabolic trough power plant expansion tanks

NASA Astrophysics Data System (ADS)

Glatzmaier, Greg C.; Cooney, Daniel A.

2017-06-01

The National Renewable Energy Laboratory and Acciona Energy North America are working together to design and implement a process system that provides a permanent solution to the issue of hydrogen buildup at parabolic trough power plants. We are pursuing a method that selectively removes hydrogen from the expansion tanks that serve as reservoirs for the heat transfer fluid (HTF) that circulates in the collector field and power block components. Our modeling shows that removing hydrogen from the expansion tanks at a design rate reduces and maintains dissolved hydrogen in the circulating HTF to a selected target level. Our collaborative work consists of several tasks that are needed to advance this process concept to a development stage, where it is ready for implementation at a commercial power plant. Our main effort is to design and evaluate likely process-unit operations that remove hydrogen from the expansion tanks at a specified rate. Additionally, we designed and demonstrated a method and instrumentation to measure hydrogen partial pressure and concentration in the expansion-tank headspace gas. We measured hydrogen partial pressure in the headspace gas mixture using a palladium-alloy membrane, which is permeable exclusively to hydrogen. The membrane establishes a pure hydrogen gas phase that is in equilibrium with the hydrogen in the gas mixture. We designed and fabricated instrumentation, and demonstrated its effectiveness in measuring hydrogen partial pressures over a range of three orders of magnitude. Our goal is to install this instrument at the Nevada Solar One power plant and to demonstrate its effectiveness in measuring hydrogen levels in the expansion tanks under normal plant operating conditions.

Design of a nanopatterned long focal-length planar focusing collector for concentrated solar power

NASA Astrophysics Data System (ADS)

Ding, Qing; Choubal, Aakash; Toussaint, Kimani C.

2017-02-01

Concentrated solar power (CSP) facilities heavily utilize parabolic troughs to collect and concentrate sunlight onto receivers that deliver solar thermal energy to heat engines for generating electricity. However, parabolic troughs are bulky and heavy and result in a large capital investment for CSP plants, thereby making it difficult for CSP technology to be competitive with photovoltaics. We present the design of a planar focusing collector (PFC) with focal length beyond the micron scale. The PFC design is based on the use of a nanostructured silver surface for linearly polarized singlewavelength light. The designed PFC consists of metallic nanogrooves on a dielectric substrate. The geometric properties, namely the width and depth, of a single-unit nanogroove allows for full control of the optical phase at desired spatial coordinates along the nanogroove short-axis for a single wavelength. Moreover, we show numerically that such phase control can be used to construct a phase front that mimics that of a cylindrical lens. In addition, we determine the concentration ratio by comparing the width of our PFC design to the cross-sectional width of its focal spot. We also determine the conversion efficiency at long focal lengths by evaluating the ratio of the collected optical power to the incoming optical power. Finally, we examine the focusing behavior across multiple wavelengths and angles of incidence. Our work shows how nano-optics and plasmonics could contribute to this important area of CSP technology.

Performance of indirectly driven capsule implosions on the National Ignition Facility using adiabat-shaping

DOE PAGES

Robey, H. F.; Smalyuk, V. A.; Milovich, J. L.; ...

2016-04-01

A series of indirectly driven capsule implosions has been performed on the National Ignition Facility to assess the relative contributions of ablation-front instability growth vs. fuel compression on implosion performance. Laser pulse shapes for both low and high-foot pulses were modified to vary ablation-front growth & fuel adiabat, separately and controllably. Two principal conclusions are drawn from this study: 1) It is shown that an increase in laser picket energy reduces ablation-front instability growth in low-foot implosions resulting in a substantial (3-10X) increase in neutron yield with no loss of fuel compression. 2.) It is shown that a decrease inmore » laser trough power reduces the fuel adiabat in high-foot implosions results in a significant (36%) increase in fuel compression together with no reduction in neutron yield. These results taken collectively bridge the space between the higher compression low-foot results and the higher yield high-foot results.« less

Design improvement and performance evaluation of solar photocatalytic reactor for industrial effluent treatment.

PubMed

Nair, Ranjith G; Bharadwaj, P J; Samdarshi, S K

2016-12-01

This work reports the details of the design components and materials used in a linear compound parabolic trough reactor constructed with an aim to use the photocatalyst for solar photocatalytic applications. A compound parabolic trough reactor has been designed and engineered to exploit both UV and visible part of the solar irradiation. The developed compound parabolic trough reactor could receive almost 88% of UV radiation along with a major part of visible radiation. The performance of the reactor has been evaluated in terms of degradation of a probe pollutant using the parameters such as rate constant, residence time and photonic efficiency. An attempt has been made to assess the performance in different ranges of solar spectrum. Finally the developed reactor has been employed for the photocatalytic treatment of a paper mill effluent using Degussa P25 as the photocatalyst. The paper mill effluent collected from Nagaon paper mill, Assam, India has been treated under both batch mode and continuous mode using Degussa P25 photocatalyst under artificial and natural solar radiation, respectively. The photocatalytic degradation kinetics of the paper mill effluent has been determined using the reduction in total organic carbon (TOC) values of the effluent. Copyright © 2015 Elsevier Inc. All rights reserved.

SHARAD Radar investigations into the initiation of spiral troughs on Planum Boreum, Mars

NASA Astrophysics Data System (ADS)

Smith, I. B.; Holt, J. W.

2010-12-01

Recent evidence demonstrates that the prominent spiral troughs of the North Polar Layered Deposits (NPLD) on Mars are not young features, having persisted and evolved during accumulation of more than 500 meters of ice [Smith and Holt, Nature, 2010]. Because of the rich stratigraphy in the NPLD, determining the processes controlling trough formation and evolution is an important step in understanding the history of ice and climate on Mars. Multiple periods of trough initiation are observed in radar data collected by the Shallow Radar (SHARAD) instrument on Mars Reconnaissance Orbiter; however, the mechanism behind trough initiation is still a mystery. Discrete radar reflectors can be associated with the onset of spiral troughs because of their stratigraphic relationships: below the reflectors the troughs do not exist, and above the troughs begin to take shape. To address the question of trough formation we have mapped these reflectors, which are assumed to represent isochrones, in more than 400 SHARAD observations throughout the NPLD. Taken together these represent the surfaces where troughs initiated, i.e. surfaces that lie directly below the first appearance of troughs. When observation geometries are favorable, we find that the onset of each trough rests on a change in slope usually at the base of a buried erosional scarp. The underlying layers end abruptly at the scarps rather than diminish or pinch out with distance, suggesting that the NPLD underwent cap-wide erosion predating trough formation. This surface morphology provides the initial conditions needed to form troughs from the combination of deposition and katabatic winds affected by surface slope. Radar observations indicate that the troughs initiated and evolved with approximately the same wavelength as can be measured today. Thus proposed hypotheses of small bedforms growing into larger wavelength structures is not supported. Locally, the unconformable contact between younger, trough-related material and older eroded surfaces is exposed at the surface. Neither the younger nor older exposed layers show small-scale bedforms, supporting this conclusion. At least two initiation surfaces can be observed in the radar data within the uppermost 500 m of the NPLD. Alternating periods of erosion and deposition are predicted to result from large changes in obliquity and insolation at the Martian north pole [Laskar et al., Nature, 2004], suggesting that trough initiation may be related to orbital forcing.

Designer Troughs

NASA Image and Video Library

2006-06-11

This MOC image shows a wide, flat-floored trough flanked by several smaller, branching troughs in the Olympica Fossae region of Mars. Dark- and intermediate-toned slope streaks -- created by dry avalanches of dust -- occur on the trough walls

A fixed collector employing reversible vee-trough concentrator and a vacuum tube receiver for high temperature solar energy systems

NASA Technical Reports Server (NTRS)

Selcuk, M. K.

1976-01-01

A solar heat collection system employing non-tracking reflectors integrated with a fixed vacuum tube receiver which achieves modest year-round concentration (about 2) of the sunlight at low capital costs is discussed. The axis of the vee-trough reflector lies in a east-west direction and requires reversal of the reflector surfaces only twice a year without disturbing the receiver tubes and associated plumbing. It collects most of the diffuse flux. The vacuum tube receiver with selective absorber has no convection losses while radiation and conduction losses are minimal. Significant cost reductions are offered since the vee-trough can be fabricated from inexpensive polished or plastic reflector laminated sheet metal covering 2/3 of the collection area, and only about 1/3 of the area is covered with the more expensive vacuum tube receivers. Thermal and economic performance of the vee-trough vacuum tube system, year-round variation of the concentration factor, incident flux, useful heat per unit area at various operation temperatures and energy cost estimates are presented. The electrical energy cost is estimated to be 77 mills/kWh, and the system construction cost is estimated to be $1140/kWe.

The origin and peculiarities of the nigerian benue trough: Another look from recent gravity data obtained from the middle benue

NASA Astrophysics Data System (ADS)

Ajayi, C. O.; Ajakaiye, D. E.

1981-12-01

The origin of the Benue trough has been a controversial subject. Previous workers in the area have evolved several theories ranging from a rift, with or without plate tectonic concepts (King, 1950; Wright, 1968, 1970; Burke et al., 1970; Grant, 1971; Olade, 1975) to a geosyncline (Lees, 1952) and a combination of both (Cratchley and Jones, 1965; Offodile, 1976) to explain the origin of the trough. One of the aims of the gravity survey, carried out in the middle Benue and discussed in this paper, was to attempt to resolve some of the problems associated with the origin of the trough as proposed by previous workers and in so doing to explain the geological peculiarities associated with the trough. Interpretations of the gravity data along two north—south profiles in the survey area indicated the existence of a rift, of normal width (about 40 km) buried under the Cretaceous cover and located between the central axis (ridge) of the trough and the northern boundary of the trough. The gravity minimum which occurs south of the central axis of the trough, was also ascribed to another rift. Thus the Benue trough is considered to consist of two parallel rifts separated by the axial ridge which partly explains the abnormal width of the trough. The interpreted models also indicate a low-angle thrust fault, with a small displacement, which may be related to the folding of the sediments in the trough and also to the asymmetry of the trough. Furthermore, the gravity data suggest that oceanic crust might not have reached the ground surface in the Benue trough, as in the Red Sea, before rifting ceased.

Development of sheet-metal parabolic-trough reflector panels

NASA Astrophysics Data System (ADS)

Biester, A. W.

1982-06-01

Efforts to develop accurate, durable, and mass producible sheet metal parabolic trough solar collectors and the associated support for the collectors are described. The design considered is similar to an automobile hood, a two-piece sheet metal structure consisting of a formed steel frame or stiffening panel and a smooth contoured skin. The two pieces may be bonded or welded to form a rigid structure, and a reflective surface applied such as a film, glass mirror, or any of the presently utilized materials. The work encompassed material selection, adhesive selection and testing, tool design and fabrication, prototype panel production, and design and development of torque tube assemblies on which the trough is inclined. Results of adhesive bonding studies are given. It is found that high volume technology can be used to produce accurate and structurally sound reflector panels, and one configuration was selected for fabrication in suitable quantities for performance testing.

A new TRNSYS component for parabolic trough collector simulation

NASA Astrophysics Data System (ADS)

Drosou, Vassiliki; Valenzuela, Loreto; Dimoudi, Argiro

2018-03-01

This study describes and evaluates a new simulation component for parabolic trough collectors (PTCs). The new simulation component is implemented in the TRNSYS software environment by means of new Type that is suitable for integration into the calculation of a whole concentrating solar thermal plant, in order to evaluate the energy production of a PTC. The main advantage of the new Type is that is derived from experimental data available on efficiency Test Reports, according to the current European and International standards, rather than the theoretical approach considered in the existing parabolic trough component of TRNSYS library. The performance of the new Type has been validated with real experimental data obtained from the DISS solar test loop in Plataforma Solar de Almería, Spain. The paper describes the modelling approach, presents the comparison of simulation results with measurements taken at the DISS facility and evaluates the results.

Life cycle assessment of a parabolic trough concentrating solar power plant and the impacts of key design alternatives.

PubMed

Burkhardt, John J; Heath, Garvin A; Turchi, Craig S

2011-03-15

Climate change and water scarcity are important issues for today's power sector. To inform capacity expansion decisions, hybrid life cycle assessment is used to evaluate a reference design of a parabolic trough concentrating solar power (CSP) facility located in Daggett, CA, along four sustainability metrics: life cycle (LC) greenhouse gas (GHG) emissions, water consumption, cumulative energy demand (CED), and energy payback time (EPBT). This wet-cooled, 103 MW plant utilizes mined nitrates salts in its two-tank, thermal energy storage (TES) system. Design alternatives of dry-cooling, a thermocline TES, and synthetically derived nitrate salt are evaluated. During its LC, the reference CSP plant is estimated to emit 26 g of CO(2eq) per kWh, consume 4.7 L/kWh of water, and demand 0.40 MJ(eq)/kWh of energy, resulting in an EPBT of approximately 1 year. The dry-cooled alternative is estimated to reduce LC water consumption by 77% but increase LC GHG emissions and CED by 8%. Synthetic nitrate salts may increase LC GHG emissions by 52% compared to mined. Switching from two-tank to thermocline TES configuration reduces LC GHG emissions, most significantly for plants using synthetically derived nitrate salts. CSP can significantly reduce GHG emissions compared to fossil-fueled generation; however, dry-cooling may be required in many locations to minimize water consumption.

DETAIL VIEW OF ARRASTRA, LOOKING SOUTHEAST. THIS OLD TECHNOLOGY IS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

DETAIL VIEW OF ARRASTRA, LOOKING SOUTHEAST. THIS OLD TECHNOLOGY IS AN ANACHRONISM OF THIS MILL. ORE WAS DUMPED INTO THE STONE LINED TROUGH. AS THE ARRASTRA TURNED LARGE STONES CONNECTED TO THE FOUR ARMS WERE DRAGGED AROUND OVER THE ORE TO CRUSH IT. IT IS CLEAR THAT THIS ARRASTRA WAS POWERED BY MACHINE THOUGH IT IS UNCLEAR EXACTLY HOW IT WAS POWERED. THE WHITE PINE TALC MINE OPENING IS SEEN IN THE DISTANCE AT THE CENTER LEFT EDGE. - Gold Hill Mill, Warm Spring Canyon Road, Death Valley Junction, Inyo County, CA

Influence of Nano-Fluid and Receiver Modification in Solar Parabolic Trough Collector Performance

NASA Astrophysics Data System (ADS)

Dharani Kumar, M.; Yuvaraj, G.; Balaji, D.; Pravinraj, R.; shanmugasundaram, Prabhu

2018-02-01

Utilization of natural renewal sources in India is very high over the past decades. Solar power is a prime source of energy available plenty in the world. In this work solar energy is modified into thermal energy by using copper absorber tube with fins. Due to low heat transfer coefficient results leading to higher thermal losses and lower thermal efficiency. In order to increase the heat transfer coefficient copper receiver tube with fins is used and as well as solid has higher thermal conductivity compare to fluid (Tio2) nano fluid is used to improve the heat transfer rate. The analyses have been carried out and take the account of parameters such as solar radiation with time variation, mass flow rate of water, temperatures.

A new simple technique for rearing F1 progeny from females of the Simulium damnosum Theobald complex.

PubMed

Raybould, J N; Barro, T; Sawadogo, R; Mordzifa, F

1982-06-01

Laboratory rearing of Simulium damnosum complex species enables female adults to be indirectly identified from their larval progeny. A simple, readily transportable rearing apparatus was developed for investigations by the Onchocerciasis Control programme by using unbreakable, easily packed and reassembled parts and by feeding the larvae at least partly with living green algae (Chlorophyceae) cultured in the laboratory. Although the larvae are sensitive to excess nitrogen compounds, the use of algae and a large volume of water obviated the need for a separate purification system in which water was circulated by an A/C electrical centrifugal pump between a container and an inclined trough in which most of the larvae developed. The rate of development was rapid giving rise to full size larvae (suitable for cytotaxonomic determination), pupae and adults. The adults were attracted into a collecting device by light. Developments to protect the larvae during electrical power failures included a slow-drying wooden rearing trough and an automatic switch to an alternative D/C power supply and pump. This technique has been in general use in O.C.P. laboratories in Benin, Ghana, Ivory Coast and Upper Volta and many thousands of larvae have been reared.

Spectrum-splitting hybrid CSP-CPV solar energy system with standalone and parabolic trough plant retrofit applications

NASA Astrophysics Data System (ADS)

Orosz, Matthew; Zweibaum, Nicolas; Lance, Tamir; Ruiz, Maritza; Morad, Ratson

2016-05-01

Sunlight to electricity efficiencies of Parabolic Trough Collector (PTC) plants are typically on the order of 15%, while commercial solar Photovoltaic (PV) technologies routinely achieve efficiencies of greater than 20%, albeit with much higher conversion efficiencies of photons at the band gap. Hybridizing concentrating solar power and photovoltaic technologies can lead to higher aggregate efficiencies due to the matching of photons to the appropriate converter based on wavelength. This can be accomplished through spectral filtering whereby photons unusable or poorly utilitized by PV (IR and UV) are passed through to a heat collection element, while useful photons (VIS) are reflected onto a concentrating PV (CPV) receiver. The mechanical design and experimental validation of spectral splitting optics is described in conjunction with system level modeling and economic analysis. The implications of this architecture include higher efficiency, lower cost hybrid CSP-PV power systems, as well as the potential to retrofit existing PTC plants to boost their output by ~ 10% at a projected investment cost of less than 1 per additional net Watt and an IRR of 18%, while preserving the dispatchability of the CSP plant's thermal energy storage.

Performance of a wind turbine over a ridged terrain

NASA Astrophysics Data System (ADS)

Santoni, Christian; Ciri, Umberto; Leonardi, Stefano

2016-11-01

Performance of wind turbines is affected by their interaction with the topography. Low momentum flow from the terrain may impinge the turbine resulting in fatigue loads that may reduce durability. However, at the same time it may promote the transport of momentum and kinetic energy into the wake improving the power production on the downstream turbines. In order to address how the topography affects the flow, Large Eddy Simulations of a wind turbine located on a wavy surface are performed. The height variation of the topography is described by a sinusoidal wave. Two different amplitudes were considered, 0 . 10 D and 0 . 05 D , where D is the rotor diameter. The wavelength has been kept constant to 3 D . The effect of the relative position of rotor and terrain geometry was assessed by placing the turbine either at the crest or at the trough of the undulated wall. NREL-5MW turbine blades were modeled using the actuator line model whereas the tower, nacelle and topography using the immersed boundary method. A simulation of a wind turbine on a flat terrain was performed as reference case. The performance of the turbine was evaluated in terms of the power production and blade load fluctuations, as well as for the energy entrainment into the wake of the turbine. The numerical simulations were performed on XSEDE TACC under Grant No. CTS070066. This work was supported by the National Science Foundation, Grant Number IIA-1243482 (the WINDINSPIRE project).

Are Vancomycin Trough Concentrations of 15 to 20 mg/L Associated With Increased Attainment of an AUC/MIC ≥ 400 in Patients With Presumed MRSA Infection?

PubMed

Hale, Cory M; Seabury, Robert W; Steele, Jeffrey M; Darko, William; Miller, Christopher D

2017-06-01

To determine whether there is an association between higher vancomycin trough concentrations and attainment of a calculated area under the concentration-time curve (AUC)/minimum inhibitory concentration (MIC) ≥400. A retrospective analysis was conducted among vancomycin-treated adult patients with a positive methicillin-resistant Staphylococcus aureus (MRSA) culture. Attainment of a calculated AUC/MIC ≥400 was compared between patients with troughs in the reference range of 15 to 20 mg/L and those with troughs in the following ranges: <10, 10 to 14.9, and >20 mg/L. Nephrotoxicity was assessed as a secondary outcome based on corrected average vancomycin troughs over 10 days of treatment. Overall, 226 patients were reviewed and 100 included. Relative to troughs ≥10, patients with vancomycin troughs <10 mg/L were 73% less likely to attain an AUC/MIC ≥400 (odds ratio [OR] 0.27, 95% confidence interval [CI]: 0.01-0.75). No difference was found in the attainment of an AUC/MIC ≥400 in patients with troughs of 10 to 14.9 mg/L and >20 mg/L when compared to patients with troughs of 15 to 20 mg/L. The mean corrected average vancomycin trough was higher in patients developing nephrotoxicity compared to those who did not (19.5 vs 14.5 mg/L, P < .001). Achieving vancomycin serum trough concentrations of 15 to 20 mg/L did not result in an increased attainment of the AUC/MIC target relative to troughs of 10 to 14.9 mg/L but may increase nephrotoxicity risk.

Adjustment and validation of a simulation tool for CSP plants based on parabolic trough technology

NASA Astrophysics Data System (ADS)

García-Barberena, Javier; Ubani, Nora

2016-05-01

The present work presents the validation process carried out for a simulation tool especially designed for the energy yield assessment of concentrating solar plants based on parabolic through (PT) technology. The validation has been carried out by comparing the model estimations with real data collected from a commercial CSP plant. In order to adjust the model parameters used for the simulation, 12 different days were selected among one-year of operational data measured at the real plant. The 12 days were simulated and the estimations compared with the measured data, focusing on the most important variables from the simulation point of view: temperatures, pressures and mass flow of the solar field, gross power, parasitic power, and net power delivered by the plant. Based on these 12 days, the key parameters for simulating the model were properly fixed and the simulation of a whole year performed. The results obtained for a complete year simulation showed very good agreement for the gross and net electric total production. The estimations for these magnitudes show a 1.47% and 2.02% BIAS respectively. The results proved that the simulation software describes with great accuracy the real operation of the power plant and correctly reproduces its transient behavior.

Sensor for Measuring Hydrogen Partial Pressure in Parabolic Trough Power Plant Expansion Tanks

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glatzmaier, Greg C.; Cooney, Daniel A.

The National Renewable Energy Laboratory and Acciona Energy North America are working together to design and implement a process system that provides a permanent solution to the issue of hydrogen buildup at parabolic trough power plants. We are pursuing a method that selectively removes hydrogen from the expansion tanks that serve as reservoirs for the heat transfer fluid (HTF) that circulates in the collector field and power block components. Our modeling shows that removing hydrogen from the expansion tanks at a design rate reduces and maintains dissolved hydrogen in the circulating HTF to a selected target level. Our collaborative workmore » consists of several tasks that are needed to advance this process concept to a development stage, where it is ready for implementation at a commercial power plant. Our main effort is to design and evaluate likely process-unit operations that remove hydrogen from the expansion tanks at a specified rate. Additionally, we designed and demonstrated a method and instrumentation to measure hydrogen partial pressure and concentration in the expansion-tank headspace gas. We measured hydrogen partial pressure in the headspace gas mixture using a palladium-alloy membrane, which is permeable exclusively to hydrogen. The membrane establishes a pure hydrogen gas phase that is in equilibrium with the hydrogen in the gas mixture. We designed and fabricated instrumentation, and demonstrated its effectiveness in measuring hydrogen partial pressures over a range of three orders of magnitude. Our goal is to install this instrument at the Nevada Solar One power plant and to demonstrate its effectiveness in measuring hydrogen levels in the expansion tanks under normal plant operating conditions.« less

Safety and tolerability of deferasirox in pediatric hematopoietic stem cell transplant recipients: one facility's five years' experience of chelation treatment.

PubMed

Maximova, Natalia; Gregori, Massimo; Simeone, Roberto; Sonzogni, Aurelio; Boz, Giulia; Fucile, Carmen; Marini, Valeria; Martelli, Antonietta; Mattioli, Francesca

2017-09-08

42 pediatric patients with iron overload, who underwent liver biopsy and DFX treatment after hematopoietic stem cell transplantation were included in the study group. The patients were divided into two groups diversified according to deferasirox trough plasma concentrations (DFX C trough ) with cut-off equal to10 mcg/mL. The average dose of DFX was 25.9 mg/kg in the DFX C trough < 10 mcg/mL group versus 19.2 mg/kg in the DFX C trough > 10 mcg/mL group ( p =0,0003). The mean duration of DFX treatment was 135.7 days in the DFX C trough < 10 mcg/mL group versus 41.8 days in the DFX C trough > 10 mcg/mL group ( p <0.0001). The mean tissue iron concentration in the DFX C trough < 10 mcg/mL group was 261.9 μmol/g versus 133.4 μmol/g in the DFX C trough > 10 mcg/mL group ( p < 0.0001). 21 patients (100%) in the DFX C trough > 10 mcg/mL group had ductopenia which was complete in 47.6% of them and severe in 52.4%. All patients with particularly high C trough (> 25 mcg/mL) were found to have total ductopenia. 90.5% of all deferasirox-related adverse events and 100% of major adverse events occurred in the DFX C trough > 10 mcg/mL group. In the DFX C trough < 10 mcg/mL group only one patient interrupted chelation therapy versus 16 (84.2%) patients in the DFX C trough > 10 mcg/mL group. We would recommend a close monitoring in pediatric hematopoietic transplant recipients subjected to deferasirox-based therapy because we have observed a high incidence of adverse events and discontinuation of chelation treatment.

Area-under-the-curve monitoring of cyclosporine therapy: Performance of different assay methods and their target concentrations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grevel, J.; Napoli, K.L.; Gibbons, S.

1990-01-01

The measurement of areas under the concentration-time curve (AUC) was recently introduced as an alternative to trough level monitoring of cyclosporine therapy. The AUC is divided by the oral dosing interval to calculate an average concentration. All measurements are performed at clinical steady state. The initial evaluation of AUC monitoring showed advantages over trough level monitoring with concentrations of cyclosporine measured in serum by the polyclonal radioimmunoassay of Sandoz. This assay technique is no longer available and the following assays were performed in parallel during up to 173 AUC determinations in 51 consecutive renal transplant patients: polyclonal fluorescence polarization immunoassaymore » of Abbott in serum, specific and nonspecific monoclonal radioimmunoassays using {sup 3}H and {sup 125}I tracers in serum and whole blood, and high performance liquid chromatography in whole blood. Both trough levels and average concentrations at steady state measured by those different techniques were significantly correlated with the oral dose. The best correlation (r2 = 0.54) was shown by average concentrations measured in whole blood by the specific monoclonal radioimmunoassay of Sandoz ({sup 3}H tracer). This monitoring technique was also associated with the smallest absolute error between repeated observations in the same patient while the oral dose rate remained the same or was changed. Both allegedly specific monoclonal radioimmunoassays (with {sup 3}H and {sup 125}I tracer) measured significantly higher concentrations than the liquid chromatography.« less

Tectonic controls of a backarc trough-fill turbidite system: The Pliocene Tamugigawa Formation in the Niigata Shin'etsu inverted rift basin, Northern Fossa Magna, central Japan

NASA Astrophysics Data System (ADS)

Takano, Osamu; Tateishi, Masaaki; Endo, Masataka

2005-05-01

The Pliocene Tamugigawa Formation in the Niigata-Shin'etsu inverted rift basin, Northern Fossa Magna, located in the junction zone of the NE and SW Japan arcs, demonstrates a trough-fill turbidite system, which is topographically controlled in depositional style and shows notable contrasts in depositional architecture from sandy radial-fan-type turbidite systems. The Tamugigawa trough-fill turbidite system shows an elongated morphology parallel to the basin extent and facies associations consisting of trough-fill, lateral-supply and trough-side elements. The trough-fill elements comprise thick-bedded sheet sandstone and sheet-flow turbidite associations, which show sheet-like sedimentation configuration, instead of depositional lobes, without distinct upward fining and coarsening successions. The lateral-supply elements form an intra-trough small fan along a lateral sediment-supply system into the troughs, and consist mainly of coarser-grained distributary-channel fills and sheet sandstones. The trough-side elements consist of slope-mudstone and spillover associations, which were deposited on the structural highs beside the troughs. The Tamugigawa trough-fill turbidites were deposited through three phases: (a) initial ponding stage with thick, sheet sandstones provided by the lateral-supply system, (b) main filling stage with sheet-flow turbidites provided by the longitudinal supply system, and (c) filled-up stage characterized by minor-scale channel-levee systems. Basin-wide tectono-sedimentary studies reveal that the trough-fill turbidites were characteristically formed during the compressional-stress-field stage related to basin inversion. The compressional stress induced basin-floor syndepositional folding and coarse clastic supply from the uplifted provenance, resulting in topographically restricted turbidite deposition within the troughs. In contrast, turbidites of the post-rift stage, prior to basin inversion, show no topographical control because of the simple and wide rift-basin topography, relative to the amount of sediment supply. It is concluded that the trough-fill turbidites of the Niigata-Shin'etsu basin have been strongly affected by basin tectonics in their depositional architecture and formation phases.

The Effect of Age and Weight on Vancomycin Serum Trough Concentrations in Pediatric Patients

PubMed Central

Madigan, Theresa; Sieve, Ronald M.; Graner, Kevin K.; Banerjee, Ritu

2013-01-01

Background Vancomycin treatment failure has been associated with low serum vancomycin trough concentrations, prompting recommendations to increase the daily doses in adults and children. Despite more aggressive vancomycin dosing, there continues to be significant variability in vancomycin trough concentrations in pediatric patients. Methods To determine if vancomycin trough concentrations in pediatric patients differ by age and weight, we reviewed records of hospitalized patients who received vancomycin between 2008 and 2012. Patients were divided into groups that received vancomycin 40 mg/kg/day (2008 to 2009) or 60 mg/kg/day (2010 to 2012). Vancomycin trough concentrations were compared between groups and within the 60-mg/kg/day group, stratified by patient age and weight. Results After increasing the vancomycin dose from 40 mg/kg/day to 60 mg/kg/day, initial trough concentrations increased significantly in patients younger than 2 and greater than 6 years of age, but not in patients between the ages of 2 and 5 years. In the 60-mg/kg/day group, only 16.7% of patients between 2 and 5 years of age had initial trough concentrations in the therapeutic range (10 mcg/mL to 20 mcg/mL). Initial trough concentrations were therapeutic in a greater proportion of patients ages 6 years to 12 years (38.7%) and 13 years to 18 years (63.0%). Patients between the ages of 13 and 18 had the highest proportion of supratherapeutic initial vancomycin trough concentrations (14.8%). Patients weighing > 50 kg had significantly higher trough concentrations than patients ≤ 50 kg (17.1 mcg/mL vs. 9.3 mcg/mL; p<0.001). Conclusion Although increasing the vancomycin dose from 40 mg/kg/day to 60 mg/kg/day led to a significant increase in vancomycin trough concentrations, a large proportion of patients receiving 60 mg/kg/day of vancomycin had trough concentrations outside of the therapeutic range. Specifically, patients younger than 6 years tend to have low trough concentrations, while adolescents and children > 50 kg are more likely to have elevated trough concentrations. Vancomycin dosing strategies in pediatric patients should consider age and weight as well as renal function and indication. PMID:23864541

GPS/acoustic Seafloor Geodetic Observations Near the Nankai Trough Axis

NASA Astrophysics Data System (ADS)

Tadokoro, K.; Yasuda, K.; Fujii, C.; Watanabe, T.; Nagai, S.

2013-12-01

The GPS/acoustic seafloor geodetic observation system, which uses precise acoustic ranging and kinematic GPS positioning techniques, has been developed as a useful tool for observing seafloor crustal deformations associated with plate convergence and with earthquakes that occurred in ocean area including the 2011 Tohoku-oki Earthquake of Mw 9.0. Our research group installed eight seafloor benchmarks for this observation system in source areas of anticipated major interplate earthquakes along the Nankai Trough, off southwestern Japan. We have performed campaign measurement for 4-8 years until the end of 2012. The error of displacement rate is almost 5 mm/y through the monitoring for more than four years. At the northern-most potion of the Nankai (Suruga) Trough, the observed steady horizontal displacement rate is 45 mm/y toward west. Also no significant velocity difference is observed across the trough, indicating strong interplate locking up to the shallowest segments. On the other hand, site velocities are 40 mm/y in the direction of N75W at the central region of the Nankai trough, 70-90 km landward from the trough axis. Although this result is the strong evidence for interplate locking, with coupling ratios of 60-80% on the basis of the back-slip model, it has no resolution for the interplate locking at the most-shallowest segments whose depths are 0-10 km. In other words, seaward up-dip limit of locked zone is never resolved from the present seafloor benchmark network [Tadokoro et al., 2012] . Large co-seismic slips larger than 40-50 m on the shallowest interplate segment [Ito et al., 2011; Fujii et al., 2011; Iinuma et al., 2012] are the cause of the unexpected high tsunami that has attacked the pacific coasts of the Tohoku region during the Tohoku-oki Earthquake; it is, therefore, essential to understand slip deficit or strain accumulation condition near the trench axis, also for the anticipated mega-thrust earthquake at the Nankai Trough. For this reason, we installed a new seafloor benchmark in the vicinity of the Nankai Trough axis, about 15 km landward from the trough axis, on July 16, 2013. In addition, we plan to install another new benchmark on the other side of the Nankai Trough in August of this year, to directly measure the motion of the subducting Philippine Sea Plate. The coupling ratio is calculated from slip deficit divided by convergence rate. We can directly 'measure' the coupling ratio from crustal deformation at the newly-installed station on the Philippine Sea Plate, without using global plate motion models. Acknowledgments: We are grateful to the captain and crews of R/V "Asama" of Mie Prefecture Fisheries Research Institute, Japan. This study has been partly promoted by Ministry of Education, Culture, Sports, Science and Technology, Japanese Government.

Cracked Mars

NASA Technical Reports Server (NTRS)

2006-01-01

25 June 2006 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows v-shaped troughs in the Hephaestus Fossae region of Mars. Light-toned, windblown ripples reside in the very lowest parts of the troughs, as well as on the cratered upland outside the troughs. Boulders and other types of debris, which were derived from the layered rock exposed near the top of the troughs, are seen resting on the trough floors and perched on the sloping trough walls.

Location near: 21.1oN, 236.7oW Image width: 3 km (1.9 mi) Illumination from: lower left Season: Northern Spring

Novel second-stage solar concentrator for parabolic troughs

NASA Astrophysics Data System (ADS)

Collares-Pereira, Manuel; Mendes, Joao F.

1995-08-01

Conventional parabolic troughs can be combined with second stage concentrators (SSC), to increase temperature and pressure inside the absorber, making possible the direct production of steam, improving substantially the overall system efficiency and leading to a new generation of distributed solar power plants. To attain this objective, research is needed at the optical, thermodynamic, system control, and engineering levels. In what concerns the receiver of such a system, different practical solutions have been proposed recently and in the past for the geometry of the second stage concentrator: CPC type and others. In this work we discuss these solutions and we propose a new one, 100% efficient in energy collection while reaching a total concentration ratio which is almost 65% of the thermodynamic limit. This SSC has an asymmetric elliptical geometry, rendering possible a smooth solution for the reflectors while maintaining a reasonable size for the receiver.

Long-Term Heating to Improve Receiver Performance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Glatzmaier, Greg C.; Cable, Robert; Newmarker, Marc

The buildup of hydrogen in the heat transfer fluid (HTF) that circulates through components of parabolic trough power plants decreases receiver thermal efficiency, and ultimately, it decreases plant performance and electricity output. The generation and occurrence of hydrogen in the HTF provides the driving force for hydrogen to permeate from the HTF through the absorber tube wall and into the receiver annulus. Getters adsorb hydrogen from the annulus volume until they saturate and are no longer able to maintain low hydrogen pressure. The increase in hydrogen pressure within the annulus significantly degrades thermal performance of the receiver and decreases overallmore » power-plant efficiency. NREL and Acciona Energy North America (Acciona) are developing a method to control the levels of dissolved hydrogen in the circulating HTF. The basic approach is to remove hydrogen from the expansion tanks of the HTF subsystem at a rate that maintains hydrogen in the circulating HTF to a target level. Full-plant steady-state models developed by the National Renewable Energy Laboratory (NREL) predict that if hydrogen is removed from the HTF within the expansion tanks, the HTF that circulates through the collector field remains essentially free of hydrogen until the HTF returns to the power block in the hot headers. One of the key findings of our modeling is the prediction that hydrogen will reverse-permeate out of the receiver annulus if dissolved hydrogen in the HTF is kept sufficiently low. To test this prediction, we performed extended heating of an in-service receiver that initially had high levels of hydrogen in its annulus. The heating was performed using NREL's receiver test stand. Results of our testing showed that receiver heat loss steadily decreased with daily heating, resulting in a corresponding improvement in receiver thermal efficiency.« less

Object-oriented simulation model of a parabolic trough solar collector: Static and dynamic validation

NASA Astrophysics Data System (ADS)

Ubieta, Eduardo; Hoyo, Itzal del; Valenzuela, Loreto; Lopez-Martín, Rafael; Peña, Víctor de la; López, Susana

2017-06-01

A simulation model of a parabolic-trough solar collector developed in Modelica® language is calibrated and validated. The calibration is performed in order to approximate the behavior of the solar collector model to a real one due to the uncertainty in some of the system parameters, i.e. measured data is used during the calibration process. Afterwards, the validation of this calibrated model is done. During the validation, the results obtained from the model are compared to the ones obtained during real operation in a collector from the Plataforma Solar de Almeria (PSA).

Paleocene Pacific Plate reorganization mirrored in formation of the Suvarov Trough, Manihiki Plateau

NASA Astrophysics Data System (ADS)

Pietsch, Ricarda; Uenzelmann-Neben, Gabriele

2016-10-01

The Suvarov Trough is a graben structure that deviates from the Danger Islands Troughs within the Manihiki Plateau, a Large Igneous Province (LIP) located in the Central Pacific. New high-resolution seismic reflection data provide evidence that the graben formed in two phases during the Paleocene (65-45 Ma). In a first phase extension occurred in southwestward direction, pulling apart the northern part of the Suvarov Trough and a parallel trending unnamed trough. In a second phase a change of extensional force direction occurred from southwest to west-northwest, forming the southern part of the Suvarov Trough that extends onto the High Plateau. The formation of the Suvarov Trough is accompanied by a series of normal fault systems that apparently formed simultaneously. Comparing the seismic results to existing Pacific paleo strain reconstructions, the timing of increased strain and local deformation direction fits well to our findings. We thus suggest that the multiple strike directions of the Suvarov Trough represent an extensional structure that was caused by the major, stepwise Pacific Plate reorganization during the Paleocene.

Low-dose factor VIII infusion in Chinese adult haemophilia A patients: pharmacokinetics evidence that daily infusion results in higher trough level than with every-other-day infusion with similar factor VIII consumption.

PubMed

Hua, B; Lee, A; Fan, L; Li, K; Zhang, Y; Poon, M-C; Zhao, Y

2017-05-01

Pharmacokinetics (PK) modelling suggests improvement of trough levels are achieved by using more frequent infusion strategy. However, no clinical study data exists to confirm or quantify improvement in trough level, particularly for low-dose prophylaxis in patients with haemophilia A. To provide evidence that low dose daily (ED) prophylaxis can increase trough levels without increasing FVIII consumption compared to every-other-day (EOD) infusion. A cross-over study on 5 IU kg -1 FVIII daily vs. 10 IU kg -1 EOD infusions, each for 14 days was conducted at the PUMCH-HTC. On the ED schedule, trough (immediate prior to infusion), and peak FVIII:C levels (30 min after infusion) were measured on days 1-5; and trough levels alone on days 7, 9, 11 and 13. For the EOD schedule, troughs, peaks and 4-h postinfusion were measured on day 1; troughs and peaks on days 3, 5, and 7; troughs alone on days 9, 11 and 13 and 24-h postinfusion on days 2, 4 and 6. FVIII inhibitors were assessed on days 0 and 14 during both infusion schedules. Six patients were enrolled. PK evidence showed that daily prophylaxis achieved higher (~2 times) steady-state FVIII trough levels compared to EOD with the same total factor consumption. The daily prophylaxis had good acceptability among patients and reduced chronic pain in the joints in some patients. Our PK study shows low-dose factor VIII daily infusion results in higher trough level than with EOD infusion with similar factor VIII consumption in Chinese adult haemophilia A patients. © 2017 John Wiley & Sons Ltd.

Aeolian sand transport over complex intertidal bar-trough beach topography

NASA Astrophysics Data System (ADS)

Anthony, Edward J.; Ruz, Marie-Hélène; Vanhée, Stéphane

2009-04-01

Aeolian sand transport on macrotidal beaches with complex intertidal bar-trough topography (ridge-and-runnel beaches) was assessed from experiments in northern France that involved measurements of wind speed, saltation, surface moisture contents, and rates of sand trapping across surveyed portions of the upper beach profile. Beaches exhibiting intertidal bars and troughs are much more complex, topographically, than simple reflective or dissipative beaches. Furthermore, the intertidal bar-trough morphology commonly exhibits strong cross-shore variations in the moisture contents of the beach surface and in patterns of bedform development. The results of four 30-minute experiments, conducted along topographically surveyed portions of the upper beach-dune toe profile, show that troughs act as extremely efficient sand interceptors, because of their permanently saturated state, which also inhibits sand mobilisation. Troughs, thus, limit or segment the dry fetch during conditions of intermittent saltation. Flow lines, inferred from the wind profiles, suggest that complex interactions at the boundary layer are generated by the bar-trough topography. Troughs systematically appear to be characterised by air expansion, while bar faces generate ramp wind acceleration for onshore winds, and sometimes immediate downwind deceleration for offshore winds. These effects may also contribute to cross-shore variations in the rates of sand trapping. Finally, a simple conceptual model of effective fetch development, integrating the effects of the spring-neap tidal range and of gross bar-trough morphological variability over time, is proposed for bar-trough beaches. The model highlights the key theme of fetch segmentation induced by cross-shore differentiation in the moisture contents of the beach surface hinged on the complex topography of multiple bars and troughs.

Are Vancomycin Trough Concentrations Adequate for Optimal Dosing?

PubMed Central

Youn, Gilmer; Jones, Brenda; Jelliffe, Roger W.; Drusano, George L.; Rodvold, Keith A.; Lodise, Thomas P.

2014-01-01

The current vancomycin therapeutic guidelines recommend the use of only trough concentrations to manage the dosing of adults with Staphylococcus aureus infections. Both vancomycin efficacy and toxicity are likely to be related to the area under the plasma concentration-time curve (AUC). We assembled richly sampled vancomycin pharmacokinetic data from three studies comprising 47 adults with various levels of renal function. With Pmetrics, the nonparametric population modeling package for R, we compared AUCs estimated from models derived from trough-only and peak-trough depleted versions of the full data set and characterized the relationship between the vancomycin trough concentration and AUC. The trough-only and peak-trough depleted data sets underestimated the true AUCs compared to the full model by a mean (95% confidence interval) of 23% (11 to 33%; P = 0.0001) and 14% (7 to 19%; P < 0.0001), respectively. In contrast, using the full model as a Bayesian prior with trough-only data allowed 97% (93 to 102%; P = 0.23) accurate AUC estimation. On the basis of 5,000 profiles simulated from the full model, among adults with normal renal function and a therapeutic AUC of ≥400 mg · h/liter for an organism for which the vancomycin MIC is 1 mg/liter, approximately 60% are expected to have a trough concentration below the suggested minimum target of 15 mg/liter for serious infections, which could result in needlessly increased doses and a risk of toxicity. Our data indicate that adjustment of vancomycin doses on the basis of trough concentrations without a Bayesian tool results in poor achievement of maximally safe and effective drug exposures in plasma and that many adults can have an adequate vancomycin AUC with a trough concentration of <15 mg/liter. PMID:24165176

Identification of Risk Factors for Nephrotoxicity in Patients Receiving Extended-Duration, High-Trough Vancomycin Therapy

PubMed Central

Contreiras, Claire; Legal, Michael; Lau, Tim T Y; Thalakada, Rosanne; Shalansky, Stephen; Ensom, Mary H H

2014-01-01

Background: In the past, impurities in vancomycin formulations were thought to contribute to nephrotoxicity. In contrast, when current, purer formulations are dosed at conventional trough levels (i.e., 5–15 mg/L), the incidence of nephrotoxicity is relatively low. Recent guidelines have recommended targeting higher vancomycin trough levels in treatment of complicated methicillin-resistant Staphylococcus aureus infections. Dosing based on these higher trough levels may be associated with nephrotoxicity, so the potential risk factors for vancomycin-associated nephrotoxicity require clearer definition. Objectives: To determine the occurrence of nephrotoxicity in patients receiving more than 7 days of vancomycin therapy with high trough levels (15–20 mg/L) and to identify and evaluate specific risk factors related to development of vancomycin-associated nephrotoxicity (i.e., serum creatinine ≥ 44.2 μmol/L or increase ≥ 50% [i.e., ≥ 26.2 μmol/L] from baseline on 2 consecutive days). Methods: Health care records were reviewed for patients seen at 2 major teaching hospitals between January 2008 and March 2011. Patients who had attained high trough levels of vancomycin were screened for eligibility. Patients with unstable renal function, those undergoing hemodialysis, and those for whom dosage and/or sampling times were unclear were excluded. Univariate and multivariate analyses were performed to identify risk factors associated with nephrotoxicity. Univariate variables with p < 0.1 were included in the logistic regression model. Results: Of the 176 patients with high trough levels included in the analysis, 24 (14%) experienced nephrotoxicity. In univariate analysis, admission to a general medicine unit (the setting of care for 16 [67%] of the 24 patients with nephrotoxicity) and extended duration of vancomycin treatment were identified as risk factors for nephrotoxicity (p < 0.1). Other risk factors included gastrointestinal comorbidity (p = 0.056), malignancy (p = 0.044), and febrile neutropenia (p = 0.032). Multivariate analysis identified treatment on general medicine units and treatment courses longer than 7 days as independent predictors of vancomycin-associated nephrotoxicity. Conclusion: Patients being treated on general medicine units and those receiving vancomycin for more than 7 days had an increased likelihood of experiencing nephrotoxicity. The increased risk for patients on general medicine units is likely multifactorial. The relationship between treatment duration and risk of nephrotoxicity appeared to be linear. When using extended-duration, high-trough vancomycin therapy, clinicians should be vigilant in monitoring for nephrotoxicity. PMID:24799722

Energy saving analysis on mine-water source heat pump in a residential district of Henan province, central China

NASA Astrophysics Data System (ADS)

Wang, Hong; Duan, Huanlin; Chen, Aidong

2018-02-01

In this paper, the mine-water source heat pump system is proposed in residential buildings of a mining community. The coefficient of performance (COP) and the efficiency of exergy are analyzed. The results show that the COP and exergy efficiency of the mine-water source heat pump are improved, the exergy efficiency of mine-water source heat pump is more than 10% higher than that of the air source heat pump.The electric power conservation measure of “peak load shifting” is also emphasized in this article. It shows that itis a very considerable cost in the electric saving by adopting the trough period electricity to produce hot water. Due to the proper temperature of mine water, the mine-watersource heat pump unit is more efficient and stable in performance, which further shows the advantage of mine-water source heat pump in energy saving and environmental protection. It provides reference to the design of similar heat pump system as well.

Measuring the Optical Performance of Evacuated Receivers via an Outdoor Thermal Transient Test: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kutscher, C.; Burkholder, F.; Netter, J.

2011-08-01

Modern parabolic trough solar collectors operated at high temperatures to provide the heat input to Rankine steam power cycles employ evacuated receiver tubes along the collector focal line. High performance is achieved via the use of a selective surface with a high absorptance for incoming short-wave solar radiation and a low emittance for outgoing long-wave infrared radiation, as well as the use of a hard vacuum to essentially eliminate convective and conductive heat losses. This paper describes a new method that determines receiver overall optical efficiency by exposing a fluid-filled, pre-cooled receiver to one sun outdoors and measuring the slopemore » of the temperature curve at the point where the receiver temperature passes the glass envelope temperature (that is, the point at which there is no heat gain or loss from the absorber). This transient test method offers the potential advantages of simplicity, high accuracy, and the use of the actual solar spectrum.« less

Solar photochemical process engineering for production of fuels and chemicals

NASA Technical Reports Server (NTRS)

Biddle, J. R.; Peterson, D. B.; Fujita, T.

1984-01-01

The engineering costs and performance of a nominal 25,000 scmd (883,000 scfd) photochemical plant to produce dihydrogen from water were studied. Two systems were considered, one based on flat-plate collector/reactors and the other on linear parabolic troughs. Engineering subsystems were specified including the collector/reactor, support hardware, field transport piping, gas compression equipment, and balance-of-plant (BOP) items. Overall plant efficiencies of 10.3 and 11.6% are estimated for the flat-plate and trough systems, respectively, based on assumed solar photochemical efficiencies of 12.9 and 14.6%. Because of the opposing effects of concentration ratio and operating temperature on efficiency, it was concluded that reactor cooling would be necessary with the trough system. Both active and passive cooling methods were considered. Capital costs and energy costs, for both concentrating and non-concentrating systems, were determined and their sensitivity to efficiency and economic parameters were analyzed. The overall plant efficiency is the single most important factor in determining the cost of the fuel.

Solar photochemical process engineering for production of fuels and chemicals

NASA Technical Reports Server (NTRS)

Biddle, J. R.; Peterson, D. B.; Fujita, T.

1985-01-01

The engineering costs and performance of a nominal 25,000 scmd (883,000 scfd) photochemical plant to produce dihydrogen from water were studied. Two systems were considered, one based on flat-plate collector/reactors and the other on linear parabolic troughs. Engineering subsystems were specified including the collector/reactor, support hardware, field transport piping, gas compression equipment, and balance-of-plant (BOP) items. Overall plant efficiencies of 10.3 and 11.6 percent are estimated for the flat-plate and trough systems, respectively, based on assumed solar photochemical efficiencies of 12.9 and 14.6 percent. Because of the opposing effects of concentration ratio and operating temperature on efficiency, it was concluded that reactor cooling would be necessary with the trough system. Both active and passive cooling methods were considered. Capital costs and energy costs, for both concentrating and non-concentrating systems, were determined and their sensitivity to efficiency and economic parameters were analyzed. The overall plant efficiency is the single most important factor in determining the cost of the fuel.

Evaluation of the trough-type rain gage

Treesearch

Irvin C. Reigner

1964-01-01

Although infrequently used, the trough-type rain gage has been described as aerodynamically the most efficient of gages (Hayes and Kittredge 1949). This applies only to the commercial semicircular eave-gutter type of trough and not to troughs rectangular in cross-section. The latter, as well as the upright cylindrical type of gage, produces greater disturbances in the...

Multi-Scale Peak and Trough Detection Optimised for Periodic and Quasi-Periodic Neuroscience Data.

PubMed

Bishop, Steven M; Ercole, Ari

2018-01-01

The reliable detection of peaks and troughs in physiological signals is essential to many investigative techniques in medicine and computational biology. Analysis of the intracranial pressure (ICP) waveform is a particular challenge due to multi-scale features, a changing morphology over time and signal-to-noise limitations. Here we present an efficient peak and trough detection algorithm that extends the scalogram approach of Scholkmann et al., and results in greatly improved algorithm runtime performance. Our improved algorithm (modified Scholkmann) was developed and analysed in MATLAB R2015b. Synthesised waveforms (periodic, quasi-periodic and chirp sinusoids) were degraded with white Gaussian noise to achieve signal-to-noise ratios down to 5 dB and were used to compare the performance of the original Scholkmann and modified Scholkmann algorithms. The modified Scholkmann algorithm has false-positive (0%) and false-negative (0%) detection rates identical to the original Scholkmann when applied to our test suite. Actual compute time for a 200-run Monte Carlo simulation over a multicomponent noisy test signal was 40.96 ± 0.020 s (mean ± 95%CI) for the original Scholkmann and 1.81 ± 0.003 s (mean ± 95%CI) for the modified Scholkmann, demonstrating the expected improvement in runtime complexity from [Formula: see text] to [Formula: see text]. The accurate interpretation of waveform data to identify peaks and troughs is crucial in signal parameterisation, feature extraction and waveform identification tasks. Modification of a standard scalogram technique has produced a robust algorithm with linear computational complexity that is particularly suited to the challenges presented by large, noisy physiological datasets. The algorithm is optimised through a single parameter and can identify sub-waveform features with minimal additional overhead, and is easily adapted to run in real time on commodity hardware.

Electrolyzed water as novel technology to improve hygiene of drinking water for dairy ewes.

PubMed

Bodas, R; Bartolomé, D J; Tabernero De Paz, M J; Posado, R; García, J J; Rodríguez, L; Olmedo, S; Martín-Diana, A B

2013-12-01

Tap water alone (TW) or treated with 3% of slightly acidic electrolyzed water (SAEW) were used in this experiment to study its effect on water quality, blood biochemical parameters and milk yield and composition. Each type of water was supplied to one group of 10 milking ewes for 25 days. Weekly water samples from troughs were taken. On days 1, 12 and 25, milk yield was measured, and milk and blood samples were taken. SAEW reduced (P < 0.05) bacterial counts (aerobic mesophilic, total coliform and streptococcus). Blood gases, biochemical parameters and milk yield and its composition were not affected (P > 0.05). SAEW can be used at 3% rate as a powerful and economic agent for sanitizing drinking water for dairy ewes with no effects on animal performance. Copyright © 2013 Elsevier Ltd. All rights reserved.

Estimating the Performance and Economic Value of Multiple Concentrating Solar Power Technologies in a Production Cost Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jorgenson, Jennie; Denholm, Paul; Mehos, Mark

2013-12-01

Concentrating solar power with thermal energy storage (CSP-TES) is a unique source of renewable energy in that the solar thermal energy can be dispatched similarly to conventional thermal generation. However, CSP-TES plants are energy-limited, meaning that their response might be restricted by solar availability. Therefore, the use of this limited solar energy must be optimally scheduled toprovide the greatest value to the system. The timing of CSP-TES dispatch depends on a variety of factors, including electricity demand patterns, the penetration of variable generation sources, and the configuration of the CSP-TES plant itself. We use an established CSP-TES modeling framework inmore » a commercially available production cost model to compare the dispatch and value of two CSP-TEStechnologies (molten salt towers and parabolic troughs) in a Colorado test system. In addition, we consider a range of configuration parameters, such as the solar multiple and thermal energy storage limit, to evaluate how the operational and capacity value varies with plant configuration.« less

Two new methods used to simulate the circumferential solar flux density concentrated on the absorber of a parabolic trough solar collector

NASA Astrophysics Data System (ADS)

Guo, Minghuan; Wang, Zhifeng; Sun, Feihu

2016-05-01

The optical efficiencies of a solar trough concentrator are important to the whole thermal performance of the solar collector, and the outer surface of the tube absorber is a key interface of energy flux. So it is necessary to simulate and analyze the concentrated solar flux density distributions on the tube absorber of a parabolic trough solar collector for various sun beam incident angles, with main optical errors considered. Since the solar trough concentrators are linear focusing, it is much of interest to investigate the solar flux density distribution on the cross-section profile of the tube absorber, rather than the flux density distribution along the focal line direction. Although a few integral approaches based on the "solar cone" concept were developed to compute the concentrated flux density for some simple trough concentrator geometries, all those integral approaches needed special integration routines, meanwhile, the optical parameters and geometrical properties of collectors also couldn't be changed conveniently. Flexible Monte Carlo ray trace (MCRT) methods are widely used to simulate the more accurate concentrated flux density distribution for compound parabolic solar trough concentrators, while generally they are quite time consuming. In this paper, we first mainly introduce a new backward ray tracing (BRT) method combined with the lumped effective solar cone, to simulate the cross-section flux density on the region of interest of the tube absorber. For BRT, bundles of rays are launched at absorber-surface points of interest, directly go through the glass cover of the absorber, strike on the uniformly sampled mirror segment centers in the close-related surface region of the parabolic reflector, and then direct to the effective solar cone around the incident sun beam direction after the virtual backward reflection. All the optical errors are convoluted into the effective solar cone. The brightness distribution of the effective solar cone is supposed to be circular Gaussian type. Then a parabolic trough solar collector of Euro Trough 150 is used as an example object to apply this BRT method. Euro Trough 150 is composed of RP3 mirror facets, with the focal length of 1.71m, aperture width of 5.77m, outer tube diameter of 0.07m. Also to verify the simulated flux density distributions, we establish a modified MCRT method. For this modified MCRT method, the random rays with weighted energy elements are launched in the close-related rectangle region in the aperture plane of the parabolic concentrator and the optical errors are statistically modeled in the stages of forward ray tracing process. Given the same concentrator geometric parameters and optical error values, the simulated results from these two ray tracing methods are in good consistence. The two highlights of this paper are the new optical simulation method, BRT, and figuring out the close-related mirror surface region for BRT and the close-related aperture region for MCRT in advance to effectively simulate the solar flux distribution on the absorber surface of a parabolic trough collector.

Performance Evaluation of a Nanofluid-Based Direct Absorption Solar Collector with Parabolic Trough Concentrator

PubMed Central

Xu, Guoying; Chen, Wei; Deng, Shiming; Zhang, Xiaosong; Zhao, Sainan

2015-01-01

Application of solar collectors for hot water supply, space heating, and cooling plays a significant role in reducing building energy consumption. For conventional solar collectors, solar radiation is absorbed by spectral selective coating on the collectors’ tube/plate wall. The poor durability of the coating can lead to an increased manufacturing cost and unreliability for a solar collector operated at a higher temperature. Therefore, a novel nanofluid-based direct absorption solar collector (NDASC) employing uncoated collector tubes has been proposed, and its operating characteristics for medium-temperature solar collection were theoretically and experimentally studied in this paper. CuO/oil nanofluid was prepared and used as working fluid of the NDASC. The heat-transfer mechanism of the NDASC with parabolic trough concentrator was theoretically evaluated and compared with a conventional indirect absorption solar collector (IASC). The theoretical analysis results suggested that the fluid’s temperature distribution in the NDASC was much more uniform than that in the IASC, and an enhanced collection efficiency could be achieved for the NDASC operated within a preferred working temperature range. To demonstrate the feasibility of the proposed NDASC, experimental performances of an NDASC and an IASC with the same parabolic trough concentrator were furthermore evaluated and comparatively discussed. PMID:28347112

Performance Evaluation of a Nanofluid-Based Direct Absorption Solar Collector with Parabolic Trough Concentrator.

PubMed

Xu, Guoying; Chen, Wei; Deng, Shiming; Zhang, Xiaosong; Zhao, Sainan

2015-12-04

Application of solar collectors for hot water supply, space heating, and cooling plays a significant role in reducing building energy consumption. For conventional solar collectors, solar radiation is absorbed by spectral selective coating on the collectors' tube/plate wall. The poor durability of the coating can lead to an increased manufacturing cost and unreliability for a solar collector operated at a higher temperature. Therefore, a novel nanofluid-based direct absorption solar collector (NDASC) employing uncoated collector tubes has been proposed, and its operating characteristics for medium-temperature solar collection were theoretically and experimentally studied in this paper. CuO/oil nanofluid was prepared and used as working fluid of the NDASC. The heat-transfer mechanism of the NDASC with parabolic trough concentrator was theoretically evaluated and compared with a conventional indirect absorption solar collector (IASC). The theoretical analysis results suggested that the fluid's temperature distribution in the NDASC was much more uniform than that in the IASC, and an enhanced collection efficiency could be achieved for the NDASC operated within a preferred working temperature range. To demonstrate the feasibility of the proposed NDASC, experimental performances of an NDASC and an IASC with the same parabolic trough concentrator were furthermore evaluated and comparatively discussed.

Method and apparatus for measuring shear modulus and viscosity of a monomolecular film

DOEpatents

Abraham, B.M.; Miyano, K.; Ketterson, J.B.

1983-10-18

Apparatus for measuring the shear modulus of a monomolecular film comprises a circular trough having inwardly sloping sides containing a liquid for supporting the monolayer on the surface thereof; a circular rotor suspended above the trough such that the lower surface of the rotor contacts the surface of the liquid, positioned such that the axis of the rotor is concentric with the axis of the trough and freely rotable about its axis; means for hydrostatically compressing the monolayer in the annular region formed between the rotor and the sides of the trough; and means for rotating the trough about its axis. Preferably, hydrostatic compression of the monolayer is achieved by removing liquid from the bottom of the trough (decreasing the surface area) while raising the trough vertically along its axis to maintain the monolayer at a constant elevation (and maintain rotor contact). In order to measure viscosity, a means for rotating the rotor about its axis is added to the apparatus.

Method and apparatus for measuring shear modulus and viscosity of a monomolecular film

DOEpatents

Abraham, Bernard M.; Miyano, Kenjiro; Ketterson, John B.

1985-01-01

Instrument for measuring the shear modulus of a monomolecular film comprises a circular trough having inwardly sloping sides containing a liquid for supporting the monolayer on the surface thereof; a circular rotor suspended above the trough such that the lower surface of the rotor contacts the surface of the liquid, positioned such that the axis of the rotor is concentric with the axis of the trough and freely rotable about its axis; apparatus for hydrostatically compressing the monolayer in the annular region formed between the rotor and the sides of the trough; and apparatus for rotating the trough about its axis. Preferably, hydrostatic compression of the monolayer is achieved by removing liquid from the bottom of the trough (decreasing the surface area) while raising the trough vertically along its axis to maintain the monolayer at a constant elevation (and maintain rotor contact). In order to measure viscosity, a apparatus for rotating the rotor about its axis is added to the apparatus.

Intersociety Energy Conversion Engineering Conference, 20th, Miami Beach, FL, August 18-23, 1985, Proceedings. Volumes 1, 2, & 3

NASA Astrophysics Data System (ADS)

1985-12-01

Topics related to aerospace power are discussed, taking into account trends and issues of military space power systems technology, space station power system advanced development, the application and use of nuclear power for future spacecraft, the current status of advanced solar array technology development, the application of a parabolic trough concentrator to space station power needs, life test results of the Intelsat-V nickel-cadmium battery, and metal hydride hydrogen storage in nickel hydrogen batteries. Other subjects explored are concerned with alternative fuels, biomass energy, biomedical power, coal gasification, electric power cycles, and electric propulsion. Attention is given to an advanced terrestrial vehicle electric propulsion systems assessment, fuel cells as electric propulsion power plants, a sinewave synthesis for high efficiency dc-ac conversion, steam desulfurization of coal, leadless transfer of energy into the body to power implanted blood pumps, oil production via entrained flow pyrolysis of biomass, and a New Zealand synthetic gasoline plant.

NCAR CCM2 simulation of the modern Antarctic climate

NASA Technical Reports Server (NTRS)

Tzeng, Ren-Yow; Bromwich, David H.; Parish, Thomas R.; Chen, Biao

1994-01-01

The National Center for Atmospheric Research (NCAR) community climate model version 2 (CCM2) simulation of the circumpolar trough, surface air temperature, the polar vortex, cloudiness, winds, and atmospheric moisture and energy budgets are examined to validate the model's representation of the present-day Antarctic climate. The results show that the CCM2 can well simulate many important climate features over Antarctica, such as the location and intensity of the circumpolar trough, the coreless winter over the plateau, the intensity and horizontal distribution of the surface inversion, the speed and streamline pattern of the katabatic winds, the double jet stream feature over the southern Indian and Pacific oceans, and the arid climate over the continent. However, there are also some serious errors in the model. Some are due to old problems but some are caused by the new parameterizations in the model. The model errors over high southern latitudes can be summarized as follows: The circumpolar trough, the polar vertex, and the westerlies in midlatitudes are too strong; the semiannual cycle of the circumpolar trough is distorted compared to the observations; the low centers of the circumpolar trough and the troughs in the middle and upper troposphere are shifted eastward by 15 deg - 40 deg longitude; the surface temperatures are too cold over the plateau in summer and over the coastline in winter; the polar tropopause continues to have a cold bias; and the cloudiness is too high over the continent. These biases are induced by two major factors: (1) the cloud optical properties in tropical and middle latitudes, which cause the eastward shift of troughs and surface low centers and the error in the semiannual cycle, and (2) the cold bias of the surface air temperature, which is attributed to the oversimulation of cloudiness over the continent, especially during summer, and the uniform 2-m-thick sea ice. The constant thickness of sea ice suppresses the energy flux from the ocean to the atmosphere and hence reduces the air temperature near the coast during winter. Finally, although the simulated Antarctic climate still suffers these biases, the overall performance of the CCM2 is much better than that of the CCM1-T42. Therefore the CCM2 is good enough to be used for climate change studies, especially over Antarctica.

Relationship Between FEV1 and Patient-Reported Outcomes Changes: Results of a Meta-Analysis of Randomized Trials in Stable COPD.

PubMed

de la Loge, Christine; Tugaut, Béatrice; Fofana, Fatoumata; Lambert, Jérémy; Hennig, Michael; Tschiesner, Uta; Vahdati-Bolouri, Mitra; Segun Ismaila, Afisi; Suresh Punekar, Yogesh

2016-03-15

Background: This meta-analysis assessed the relationship between change from baseline (CFB) in spirometric measurements (trough forced expiratory volume in 1 second [FEV 1 ] and FEV 1 area under the curve [AUC]) and patient-reported outcomes (St. George's Respiratory Questionnaire total score [SGRQ] CFB, Transition Dyspnea Index [TDI] and exacerbation rates) after 6-12 months' follow-up, using study treatment-group level data. Methods: A systematic literature search was performed for randomized controlled trials of ≥24 weeks duration in adults with chronic obstructive pulmonary disease (COPD). Studies reporting ≥1 spirometric measurement and ≥1 patient-reported outcome (PRO) at baseline and at study endpoint were selected. The relationships between PROs and spirometric endpoints were assessed using Pearson correlation coefficient and meta-regression. Results: Fifty-two studies (62,385 patients) were included. Primary weighted analysis conducted at the last assessment showed a large significant negative correlation (r, -0.68 [95% confidence interval (CI); -0.77, -0.57]) between trough FEV 1 and SGRQ. Improvement of 100 mL in trough FEV 1 corresponded to a 5.9 point reduction in SGRQ. Similarly, a reduction of 4 points on SGRQ corresponded to 40 mL improvement in trough FEV 1 ( p <0.001). The weighted correlation coefficients of trough FEV 1 with TDI, exacerbation rate (all) and exacerbation rate (moderate/severe) at last assessment point were 0.57, -0.69 and -0.57, respectively (all p <0.05). For the analyses excluding placebo groups, the correlations of FEV 1 with SGRQ and TDI were lower but significant. Conclusions: A strong association exists between changes in spirometric measurements and changes in PROs.

Relationship Between FEV1 and Patient-Reported Outcomes Changes: Results of a Meta-Analysis of Randomized Trials in Stable COPD

PubMed Central

de la Loge, Christine; Tugaut, Béatrice; Fofana, Fatoumata; Lambert, Jérémy; Hennig, Michael; Tschiesner, Uta; Vahdati-Bolouri, Mitra; Segun Ismaila, Afisi; Suresh Punekar, Yogesh

2016-01-01

Background: This meta-analysis assessed the relationship between change from baseline (CFB) in spirometric measurements (trough forced expiratory volume in 1 second [FEV1] and FEV1 area under the curve [AUC]) and patient-reported outcomes (St. George’s Respiratory Questionnaire total score [SGRQ] CFB, Transition Dyspnea Index [TDI] and exacerbation rates) after 6-12 months’ follow-up, using study treatment-group level data. Methods: A systematic literature search was performed for randomized controlled trials of ≥24 weeks duration in adults with chronic obstructive pulmonary disease (COPD). Studies reporting ≥1 spirometric measurement and ≥1 patient-reported outcome (PRO) at baseline and at study endpoint were selected. The relationships between PROs and spirometric endpoints were assessed using Pearson correlation coefficient and meta-regression. Results: Fifty-two studies (62,385 patients) were included. Primary weighted analysis conducted at the last assessment showed a large significant negative correlation (r, −0.68 [95% confidence interval (CI); −0.77, −0.57]) between trough FEV1 and SGRQ. Improvement of 100 mL in trough FEV1 corresponded to a 5.9 point reduction in SGRQ. Similarly, a reduction of 4 points on SGRQ corresponded to 40 mL improvement in trough FEV1 (p<0.001). The weighted correlation coefficients of trough FEV1 with TDI, exacerbation rate (all) and exacerbation rate (moderate/severe) at last assessment point were 0.57, -0.69 and -0.57, respectively (all p<0.05). For the analyses excluding placebo groups, the correlations of FEV1 with SGRQ and TDI were lower but significant. Conclusions: A strong association exists between changes in spirometric measurements and changes in PROs. PMID:28848877

Evaluation of risk factors for vancomycin-induced nephrotoxicity.

PubMed

Park, So Jin; Lim, Na Ri; Park, Hyo Jung; Yang, Jae Wook; Kim, Min-Ji; Kim, Kyunga; In, Yong Won; Lee, Young Mee

2018-05-09

Background Vancomycin is a glycopeptide antibiotic of choice for the treatment of serious infections caused by multi-resistant Gram-positive bacteria. However, vancomycin-associated nephrotoxicity (VAN) often limits its use. Previous data suggested a few risk factors of VAN, including higher mean vancomycin trough level, higher daily doses, old age, long duration of vancomycin therapy, and concomitant nephrotoxins. Objective To evaluate the incidence and risk factors of VAN and determine whether higher vancomycin trough concentrations were associated with a greater risk for VAN. Settings A retrospective, observational, single-center study at the 1960-bed university-affiliated tertiary care hospital (Samsung Medical Center), Seoul, Korea. Method A retrospective analysis of adult patients who received vancomycin parenterally in a tertiary care medical center from March 1, 2013 to June 30, 2013 was performed. We excluded patients with a baseline serum creatinine level > 2 mg/dL and those who had a history of end-stage renal disease and dialysis at baseline. The clinical characteristics were compared between patients with nephrotoxicity and those without nephrotoxicity to identify the risk factors associated with VAN. Main outcome measure Incidence of VAN and VAN-associated risk factors were analyzed. Results Of the 315 vancomycin-treated patients, nephrotoxicity occurred in 15.2% of the patients. In multivariate analysis, higher vancomycin trough concentrations of > 20 mg∕L (OR 9.57, 95% CI 2.49-36.83, p < 0.01) and intensive care unit (ICU) residence (OR 2.86, 95% CI 1.41-5.82, p < 0.01) were independently associated with VAN. Conclusion Our findings suggest that higher vancomycin trough levels and ICU residence might be associated with a greater risk for VAN. More careful monitoring of vancomycin serum trough levels and patient status might facilitate the timely prevention of VAN.

The Relationship Between Vancomycin Trough Concentrations and AUC/MIC Ratios in Pediatric Patients: A Qualitative Systematic Review.

PubMed

Tkachuk, Stacey; Collins, Kyle; Ensom, Mary H H

2018-04-01

In adults, the area under the concentration-time curve (AUC) divided by the minimum inhibitory concentration (MIC) is associated with better clinical and bacteriological response to vancomycin in patients with methicillin-resistant Staphylococcus aureus who achieve target AUC/MIC ≥ 400. This target is often extrapolated to pediatric patients despite the lack of similar evidence. The impracticalities of calculating the AUC in practice means vancomycin trough concentrations are used to predict the AUC/MIC. This review aimed to determine the relationship between vancomycin trough concentrations and AUC/MIC in pediatric patients. We searched the MEDLINE and Embase databases, the Cochrane Database of Systematic Reviews, and the Cochrane Central Register of Controlled Trials using the medical subject heading (MeSH) terms vancomycin and AUC and pediatric* or paediatric*. Articles were included if they were published in English and reported a relationship between vancomycin trough concentrations and AUC/MIC. Of 122 articles retrieved, 11 met the inclusion criteria. One trial reported a relationship between vancomycin trough concentrations, AUC/MIC, and clinical outcomes but was likely underpowered. Five studies found troughs 6-10 mg/l were sufficient to attain an AUC/MIC > 400 in most general hospitalized pediatric patients. One study in patients undergoing cardiothoracic surgery found a trough of 18.4 mg/l achieved an AUC/MIC > 400. Two oncology studies reported troughs ≥ 15 mg/l likely attained an AUC/MIC ≥ 400. In critical care patients: one study found a trough of 9 mg/l did not attain the AUC/MIC target; another found 7 mg/l corresponded to an AUC/MIC of 400. Potential vancomycin targets varied based on the population studied but, for general hospitalized pediatric patients, troughs of 6-10 mg/l are likely sufficient to achieve AUC/MIC ≥ 400. For MIC ≥ 2 mg/l, higher troughs are likely necessary to achieve an AUC/MIC ≥ 400. More research is needed to determine the relationships between vancomycin trough concentrations, AUC/MIC, and clinical outcomes.

Vancomycin AUC/MIC and Corresponding Troughs in a Pediatric Population

PubMed Central

Lardieri, Allison B.; Heil, Emily L.; Morgan, Jill A.

2017-01-01

OBJECTIVES Adult guidelines suggest an area under the curve/minimum inhibitory concentration (AUC/MIC) > 400 corresponds to a vancomycin trough serum concentration of 15 to 20 mg/L for methicillin-resistant Staphylococcus aureus infections, but obtaining these troughs in children are difficult. The primary objective of this study was to assess the likelihood that 15 mg/kg of vancomycin every 6 hours in a child achieves an AUC/MIC > 400. METHODS This retrospective chart review included pediatric patients >2 months to <18 years with a positive S aureus blood culture and documented MIC who received at least two doses of vancomycin with corresponding trough. Patients were divided into two groups: group 1 initially receiving ≥15 mg/kg every 6 hours, and group 2 initially receiving any other dosing ranges or intervals. AUCs were calculated four times using three pharmacokinetic methods. RESULTS A total of 36 patients with 99 vancomycin trough serum concentrations were assessed. Baseline characteristics were similar between groups. For troughs in group 1 (n = 55), the probability of achieving an AUC/MIC > 400 ranged from 16.4% to 90.9% with a median trough concentration of 11.4 mg/L, while in group 2 (n = 44) the probability of achieving AUC/MIC > 400 ranged from 15.9% to 54.5% with mean trough concentration of 9.2 mg/L. The AUC/MICs were not similar between the different pharmacokinetic methods used; however, a trapezoidal equation (Method A) yielded the highest correlation coefficient (r2 = 0.59). When dosing every 6 hours, an AUC/MIC of 400 correlated to a trough serum concentration of 11 mg/L. CONCLUSIONS The probability of achieving an AUC/MIC > 400 using only a trough serum concentration and an MIC with patients receiving 15 mg/kg every 6 hours is variable based on the method used to calculate the AUC. An AUC/MIC of 400 in children correlated to a trough concentration of 11 mg/L using a trapezoidal Method to calculate AUC. PMID:28337080

Vancomycin AUC/MIC and Corresponding Troughs in a Pediatric Population.

PubMed

Kishk, Omayma A; Lardieri, Allison B; Heil, Emily L; Morgan, Jill A

2017-01-01

Adult guidelines suggest an area under the curve/minimum inhibitory concentration (AUC/MIC) > 400 corresponds to a vancomycin trough serum concentration of 15 to 20 mg/L for methicillin-resistant Staphylococcus aureus infections, but obtaining these troughs in children are difficult. The primary objective of this study was to assess the likelihood that 15 mg/kg of vancomycin every 6 hours in a child achieves an AUC/MIC > 400. This retrospective chart review included pediatric patients >2 months to <18 years with a positive S aureus blood culture and documented MIC who received at least two doses of vancomycin with corresponding trough. Patients were divided into two groups: group 1 initially receiving ≥15 mg/kg every 6 hours, and group 2 initially receiving any other dosing ranges or intervals. AUCs were calculated four times using three pharmacokinetic methods. A total of 36 patients with 99 vancomycin trough serum concentrations were assessed. Baseline characteristics were similar between groups. For troughs in group 1 (n = 55), the probability of achieving an AUC/MIC > 400 ranged from 16.4% to 90.9% with a median trough concentration of 11.4 mg/L, while in group 2 (n = 44) the probability of achieving AUC/MIC > 400 ranged from 15.9% to 54.5% with mean trough concentration of 9.2 mg/L. The AUC/MICs were not similar between the different pharmacokinetic methods used; however, a trapezoidal equation (Method A) yielded the highest correlation coefficient (r 2 = 0.59). When dosing every 6 hours, an AUC/MIC of 400 correlated to a trough serum concentration of 11 mg/L. The probability of achieving an AUC/MIC > 400 using only a trough serum concentration and an MIC with patients receiving 15 mg/kg every 6 hours is variable based on the method used to calculate the AUC. An AUC/MIC of 400 in children correlated to a trough concentration of 11 mg/L using a trapezoidal Method to calculate AUC.

Origin and late quaternary tectonism of a western Canadian continental shelf trough

NASA Astrophysics Data System (ADS)

Moslow, Thomas F.; Luternauer, John L.; Rohr, Kristin

1991-08-01

Analyses of high resolution and multi-channel seismic profiles from the central continental shelf of western Canada ascribe a late Quaternary glacial origin to large-scale troughs. Along the margins of Moresby Trough, one of three large-scale cross-shelf bathymetric depressions in Queen Charlotte Sound, seismic profiles within Quaternary sediments show a divergence of reflectors, thickening and folding of seismic units, and concavity of reflectors suggestive of drag. Compactional subsidence, growth faulting, and compaction faulting are also observed. Fault traces commonly terminate below the seabed. Deformation of Quaternary sediments due to faulting is plastic in nature and maximum offset of reflectors is 2.5 m. The observed Quaternary deformation appears to be a product of rapid deposition, loading and subsidence of late Quaternary sediment, which is unrelated to seismic activity. In addition, Quaternary faulting was probably activated by post-glacial loading and isostatic rebound of consolidated Tertiary strata along the margins of continental shelf troughs. The presence of mass movement (slump or debris flow) deposits overlying lithified Tertiary strata along the flanks of Moresby Trough provides the only evidence of seismic activity in the study area. The lack of a mud drape over these deposits implies a late Holocene age for the timing of their emplacement. The Quaternary troughs are incised into Tertiary-aged sedimentary fill of the Queen Charlotte basin. Previous workers had interpreted seafloor escarpments paralleling the trough margins to indicate that the location of Moresby Trough was controlled by renewed or continued activity on Tertiary-aged faults. A multi-channel seismic line across Moresby Trough shows that such an escarpment on the seafloor does not correlate to faults either in the Tertiary basin fill or the underlying basement. Tertiary reflectors are continuous underneath Moresby Trough; the seafloor escarpment is an erosional feature and was not created by reactivation of Tertiary structures. Trough erosion and subsequent fill (up to 175 m thick) are entirely of Quaternary age.

Devonian salt dissolution-collapse breccias flooring the Cretaceous Athabasca oil sands deposit and development of lower McMurray Formation sinkholes, northern Alberta Basin, Western Canada

NASA Astrophysics Data System (ADS)

Broughton, Paul L.

2013-01-01

The sub-Cretaceous paleotopography underlying giant Lower Cretaceous Athabasca oil sands, northern Alberta, has an orthogonal lattice pattern of troughs up to 50 km long and 100 m deep between pairs of cross-cutting lineaments. These structures are interpreted to have been inherited from a similar pattern of dissolution collapse-subsidence troughs in the underlying Middle Devonian salt beds. Removal of more than 100 m of halite salt fragmented the overlying Upper Devonian strata into fault blocks and collapse breccias that subsided into the underlying dissolution troughs. The unusually low 1:2 to 1:3 thickness ratios of halite salts to the overlying strata resulted in the Upper Devonian strata collapse-subsidence into underlying salt dissolution troughs being more cataclysmic during the first phase of salt removal. The second phase of slower but complete salt removal between the earlier troughs resulted in a more gradual subsidence of the overlying strata. This obliterated the earlier pattern of giant cross-cutting dissolution troughs bounded by major lineaments. The collapse breccia fabrics underlying the earlier troughs differ from those from areas between the troughs. Collapse breccias underlying the large troughs often have crushed fabrics distributed in zones that rapidly pinched out between fault blocks. Breccias between troughs developed as giant mosaics of detached carbonate blocks that formed breccia pipe complexes. Multiple sinkholes up to 100 m deep aligned along multi-km linear valley trends that dissected the sub-Cretaceous paleotopography. These sinkhole trends formed orthogonal patterns inherited from underlying lattice of NW-SE and NE-SW salt structured lineaments. These cross-cutting sinkhole trends have a smaller 5 km scale reticulate pattern similar to the giant 50 km scale pattern of collapse-subsidence troughs. Other sinkholes developed as lower McMurray strata sagged when underlying Devonian fault blocks and breccia pipes differentially subsided.

The light ion trough.

NASA Technical Reports Server (NTRS)

Taylor, H. A., Jr.

1972-01-01

A distinct feature of the ion composition results from the OGO-2, 4 and 6 satellites is the light ion trough, wherein the mid-latitude concentrations of H+ and He+ decrease sharply with latitude. In contrast to the 'main trough' in electron density observed primarily as a nightside phenomenon, the light ion trough persists during both day and night. For daytime winter hemisphere conditions and for all seasons during night, the mid-latitude light ion concentration decrease is a pronounced feature. In the dayside summer and equinox hemispheres, the rate of light ion decrease with latitude is comparatively gradual, and the trough boundary is less well defined, particularly for quiet magnetic conditions. In response to magnetic storms, the light ion trough minimum moves equatorward, and deepens, consistent with earlier evidence of the contraction of the plasmasphere in response to storm time enhancements in magnetospheric plasma convection.

The Impact of AUC-Based Monitoring on Pharmacist-Directed Vancomycin Dose Adjustments in Complicated Methicillin-Resistant Staphylococcus aureus Infection.

PubMed

Stoessel, Andrew M; Hale, Cory M; Seabury, Robert W; Miller, Christopher D; Steele, Jeffrey M

2018-01-01

This study aimed to assess the impact of area under the curve (AUC)-based vancomycin monitoring on pharmacist-initiated dose adjustments after transitioning from a trough-only to an AUC-based monitoring method at our institution. A retrospective cohort study of patients treated with vancomycin for complicated methicillin-resistant Staphylococcus aureus (MRSA) infection between November 2013 and December 2016 was conducted. The frequency of pharmacist-initiated dose adjustments was assessed for patients monitored via trough-only and AUC-based approaches for trough ranges: 10 to 14.9 mg/L and 15 to 20 mg/L. Fifty patients were included: 36 in the trough-based monitoring and 14 in the AUC-based-monitoring group. The vancomycin dose was increased in 71.4% of patients when troughs were 10 to 14.9 mg/L when a trough-only approach was used and in only 25% of patients when using AUC estimation ( P = .048). In the AUC group, the dose was increased only when AUC/minimum inhibitory concentration (MIC) <400; unchanged regimens had an estimated AUC/MIC ≥400. The AUC-based monitoring did not significantly increase the frequency of dose reductions when trough concentrations were 15 to 20 mg/L (AUC: 33.3% vs trough: 4.6%; P = .107). The AUC-based monitoring resulted in fewer patients with dose adjustments when trough levels were 10 to 14.9 mg/L. The AUC-based monitoring has the potential to reduce unnecessary vancomycin exposure and warrants further investigation.

Fabrication of trough-shaped solar collectors

DOEpatents

Schertz, William W.

1978-01-01

There is provided a radiant energy concentration and collection device formed of a one-piece thin-walled plastic substrate including a plurality of nonimaging troughs with certain metallized surfaces of the substrate serving as reflective side walls for each trough. The one-piece plastic substrate is provided with a seating surface at the bottom of each trough which conforms to the shape of an energy receiver to be seated therein.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schuett, K.J.; Pawlak, J.P.; Traina, L.

No. 13 Blast Furnace at US Steel`s Gary Works is a 35 tuyere furnace with a 36.5 ft. hearth capable of producing over 9,000 tons of hot metal per day. The current casthouse design was placed in service following the second reline in the fall of 1979. This design anticipated daily production rates averaging 7,500 tons of hot metal per day and provided for removable troughs at two of the three tapholes. At the time, the troughs were rammed with a high alumina/silicon carbide granular ramming material that provided the operators with trough campaign lives between 60,000--70,000 tons of hotmore » metal produced. As refractory technology progressed, low cement/low moisture castables were introduced to the trough systems on No. 13 Blast Furnace. The immediate success of the castables was tempered by emergence of a new unexpected problem. That problem was the thermal expansion of the castable. The paper describes the problems that resulted in the need to modify the trough design, the new design of the trough, and its improvement in iron trough campaign life and reliability.« less

Designing Better Water Troughs: Does Trough Color Influence Dairy Cows' Preference?

PubMed

Lemos Teixeira, Dayane; Hötzel, Maria José; Pinheiro Machado Filho, Luiz Carlos; Cazale, José Daniel; Enríquez-Hidalgo, Daniel

2017-01-01

Eighteen lactating dairy cows were used to elucidate their preference for green, grey, or red troughs. The herd was managed under a rotational grazing system with ad-libitum access to water until 11:30 h. For 9 days, all cows were tested individually following the afternoon milking. Cows drank similar quantities, spent a similar amount of time drinking, and took a similar number of sips from the 3 trough colors (p > .05). In 75% of the tests, cows drank more than 95% of the test period from the same trough. Within this time, the percentage of choices did not differ among colors (33.3% green, 39.0% grey, and 27.7% red). When they chose the red trough, cows spent less time drinking (p ≤ .05) and tended to take fewer sips (p = .07), which could suggest a partial aversion to this color. Suboptimal water trough design may have long-term negative effects on both the production and welfare of dairy cattle; however, the results suggest that color does not play a major role in the drinking behavior of dairy cows.

New sidescan sonar and gravity evidence that the Nova-Canton Trough is a fracture zone

NASA Astrophysics Data System (ADS)

Joseph, Devorah; Taylor, Brian; Shor, Alexander N.

1992-05-01

A 1990 sidescan sonar survey in the eastern region of the Nova-Canton Trough mapped 138°-striking abyssal-hill fabric trending into 70°-striking trough structures. The location and angle of intersection of the abyssal hills with the eastern Nova-Canton Trough effectively disprove a spreading-center origin of this feature. Free-air gravity anomalies derived from satellite altimetry data show continuity, across the Line Islands, of the Nova-Canton Trough with the Clipperton Fracture Zone. The Canton-Clipperton trend is copolar, about a pole at 30°S, 152°W, with other coeval Pacific-Farallon fracture-zone segments, from the Pau to Marquesas fracture zones. This copolarity leads us to postulate a Pacific-Farallon spreading pattern for the magnetic quiet zone region north and east of the Manihiki Plateau, with the Nova-Canton Trough originating as a transform fault in this system.

Properties of solar generators with reflectors and radiators

NASA Astrophysics Data System (ADS)

Ebeling, W. D.; Rex, D.; Bierfischer, U.

1980-06-01

Radiation cooled concentrator systems using silicon and GaAs cells were studied. The principle of radiation cooling by the reflector surfaces is discussed for cylindrical parabolic reflectors (SARA), truncated hexagonal pyramids, and a small trough configuration. Beam paths, collection properties for imperfect orientation, and thermal optimization parameters were analyzed. The three concentrating systems with radiation cooling offer advantages over the plane panel and over the large trough. With silicon solar cells they exhibit considerably lower solar cell consumption per Kw and also lower mass per kW. With GaAs cells the SARA system reduces the number of solar cells needed per kW to less than 10%. Also in all other cases SARA offers the best values for alpha and F sub sol, as long as narrow angular tolerances of the panel orientation can be met. Analysis of the energy collecting properties for imperfect orientation shows the superiority of the hexagonal concentrator. This device can produce power for even large angles between the sun and the panel normal.

Topography of Valles Marineris: Implications for erosional and structural history

NASA Technical Reports Server (NTRS)

Lucchitta, B. K.; Isbell, N. K.; Howington-Kraus, A.

1994-01-01

Compilation of a simplified geologic/geomorphic map onto digital terrain models of the Valles Marineris permitted an evaluation of elevations in the vicinity of the troughs and the calculation of depth of troughs below surrounding plateaus, thickness of deposits inside the troughs, volumes of void spaces above geologic/geomorphic units, and volumes of deposits. The central troughs north Ophir, north and central Candor, and north Melas Chasmata lie as much as 11 km below the adjacent plateaus. In Ophir and Candor chasmata, interior layered deposits reach 8 km in elevation. If the deposits are lacustrine and if all troughs were interconnected, lake waters standing 8 km high would have spilled out of Coprates Chasma onto the surrounding plateaus having surface elevations of only 4-5 km. On the other hand, the troughs may not have been interconnected at the time of interior-deposit emplacement; they may have formed isolated ancestral basins. The existence of such basins is supported by independent structural and stratigraphic evidence. The ancestral basins may have eventually merged, perhaps through renewed faulting, to form northern subsidiary troughs in Ophir and Candor Chasmata and the Coprates/north Melas/Ius graben system. The peripheral troughs are only 2-5 km deep, shallower than the central troughs. Chaotic terrain is seen in the peripheral troughs near a common contour level of about 4 km on the adjacent plateaus, which supports the idea of release of water under artesian pressure from confined aquifers. The layered deposits in the peripheral troughs may have formed in isolated depressions that harbored lakes and predated the formation of the deep outflow channels. (If these layered deposits are of volcanic origin, they may have been emplaced beneath ice in the manner of table mountains.) Areal and volumetric computations show that erosion widened the troughs by about one-third and that deposits occupy one-sixth of the interior space. Even though the volume eroded is larger than the volume deposited, topographic and geologic considerations imply that material eroded from trough walls was probably part of the interior layered deposits but not their sole source. Additional material may have come from subterranean piping, from reworking of local disintegration products on the floors, such as chaotic materials, or from eolian influx. But overall it is likely that the additional material is volcanic and that it forms mostly the upper, more diversely bedded layers of the interior deposits.

The Skaergaard trough layering: sedimentation in a convecting magma chamber

NASA Astrophysics Data System (ADS)

Vukmanovic, Z.; Holness, M. B.; Monks, K.; Andersen, J. C. Ø.

2018-05-01

The upper parts of the floor cumulates of the Skaergaard Intrusion, East Greenland, contain abundant features known as troughs. The troughs are gently plunging synformal structures comprising stacks of crescentic modally graded layers with a sharply defined mafic base that grades upward into plagioclase-rich material. The origin of the troughs and layering is contentious, attributed variously to deposition of mineral grains by magmatic currents descending from the nearby walls, or to in situ development by localised recrystallisation during gravitationally-driven compaction. They are characterised by outcrop-scale features such as mineral lineations parallel to the trough axis, evidence of erosion and layer truncation associated with migration of the trough axis, and disruption of layering by syn-magmatic slumping. A detailed microstructural study of the modal trough layers, using electron backscatter diffraction together with geochemical mapping, demonstrates that these rocks do not record evidence for deformation by either dislocation creep or dissolution-reprecipitation. Instead, the troughs are characterised by the alignment of euhedral plagioclase crystals with unmodified primary igneous compositional zoning. We argue that the lineations and foliations are, therefore, a consequence of grain alignment during magmatic flow. Post-accumulation amplification of the modal layering occurred as a result of differential migration of an unmixed immiscible interstitial liquid, with upwards migration of the Si-rich conjugate into the plagioclase-rich upper part of the layers, whereas the Fe-rich immiscible conjugate remained in the mafic base. Both field and microstructure evidence support the origin of the troughs as the sites of repeated deposition from crystal-rich currents descending from the nearby chamber walls.

Intersection

NASA Technical Reports Server (NTRS)

2006-01-01

9 June 2006 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a small portion of a dust-covered plain directly north of Labyrinthus Noctis which is cut by three linear troughs. The two long troughs running diagonally from the lower left (southwest) to the upper right (northeast) are connected by a third, shorter trough. Boulders derived from erosion of layered rock in the trough walls are seen perched on the sloping sidewalls and resting on the trough floors among giant windblown ripples.

Location near: 0.2oN, 105.0oW Image width: 3 km (1.9 mi) Illumination from: upper left Season: Northern Spring

Bedrock morphology reveals drainage network in northeast Baffin Bay

NASA Astrophysics Data System (ADS)

Slabon, Patricia; Dorschel, Boris; Jokat, Wilfried; Freire, Francis

2018-02-01

A subglacial drainage network underneath the paleo-ice sheet off West Greenland is revealed by a new compilation of high-resolution bathymetry data from Melville Bay, northeast Baffin Bay. This drainage network is an indicator for ice streaming and subglacial meltwater flow toward the outer shelf. Repeated ice sheet advances and retreats across the crystalline basement together with subglacial meltwater drainage had their impact in eroding overdeepened troughs along ice stream pathways. These overdeepenings indicate the location of a former ice sheet margin. The troughs inherit characteristics of glacial and subglacial meltwater erosion. Most of the troughs follow tectonic weakness zones such as faults and fractures in the crystalline bedrock. Many of these tectonic features correspond with the orientations of major fault axes in the Baffin Bay region. The troughs extend from the present (sub) glacial fjord systems at the Greenland coast and parallel modern outlet-glacier pathways. The fast flowing paleo-ice streams were likely accelerated from the meltwater flow as indicated by glacial landforms within and along the troughs. The ice streams flowed along narrow tributary troughs and merged to form large paleo-ice streams bedded in the major cross-shelf troughs of Melville Bay. Apart from the troughs, a rough seabed topography characterises the bedrock, and we see a sharp geomorphic transition where ice flowed onto sedimentary rock and deposits.

Air-borne shape measurement of parabolic trough collector fields

NASA Astrophysics Data System (ADS)

Prahl, Christoph; Röger, Marc; Hilgert, Christoph

2017-06-01

The optical and thermal efficiency of parabolic trough collector solar fields is dependent on the performance and assembly accuracy of its components such as the concentrator and absorber. For the purpose of optical inspection/approval, yield analysis, localization of low performing areas, and optimization of the solar field, it is essential to create a complete view of the optical properties of the field. Existing optical measurement tools are based on ground based cameras, facing restriction concerning speed, volume and automation. QFly is an airborne qualification system which provides holistic and accurate information on geometrical, optical, and thermal properties of the entire solar field. It consists of an unmanned aerial vehicle, cameras and related software for flight path planning, data acquisition and evaluation. This article presents recent advances of the QFly measurement system and proposes a methodology on holistic qualification of the complete solar field with minimum impact on plant operation.

Increased water contamination and grow-out Pekin duck mortality when raised with water troughs compared to pin-metered water lines using a United States management system

PubMed Central

Schenk, A.; Porter, A. L.; Alenciks, E.; Frazier, K.; Best, A. A.; Fraley, S. M.; Fraley, G. S.

2016-01-01

Controversy has developed as to whether or not pin-metered water lines or water troughs are more appropriate for Pekin ducks. We hypothesized that water troughs would show improved duck body conditions and environmental quality compared to pin-metered water lines. To test this hypothesis, we housed ducks in 2 barns, one with water lines and one with water troughs. Water troughs were constructed to meet RSPCA guidelines for number and density of ducks and with recently described verandas. Ducks were divided into 4 pens per barn (n = 1,000 ducks/pen). The study was then repeated (n = 8 pens per water source) in a cross-over design so the barns each contained the opposite water source to the first experiment. We scored the ducks’ body condition using an established scoring rubric and analyzed using SAS Proc GLM-Mix as binomial data. Ducks housed with water troughs showed higher (thus worse condition; P < 0.001) scores for eyes, nostrils, feather quality, feather cleanliness, and foot pads. We also compared water condition, water quality, and duck mortality using a Student t test for both water sources each week. We found that the water troughs showed higher iron (P < 0.001), nitrites (P < 0.001), pH (P < 0.01), and bacterial growth (P < 0.001). The bacterial growth was shown to have higher (P < 0.001) E. coli, coliforms, and Staphylococcus in the water troughs. Water lines typically showed no bacterial growth in culture-based assays. Ducks housed with water troughs used greater (P = 0.001) volumes of water compared to ducks housed with water lines. Ducks with water troughs also showed a greater percent (P = 0.008) mortality at all ages compared to ducks with water lines. These data suggest that water troughs may not be beneficial for duck welfare and could adversely impact both environment and duck or human health. PMID:26769272

Increased water contamination and grow-out Pekin duck mortality when raised with water troughs compared to pin-metered water lines using a United States management system.

PubMed

Schenk, A; Porter, A L; Alenciks, E; Frazier, K; Best, A A; Fraley, S M; Fraley, G S

2016-04-01

Controversy has developed as to whether or not pin-metered water lines or water troughs are more appropriate for Pekin ducks. We hypothesized that water troughs would show improved duck body conditions and environmental quality compared to pin-metered water lines. To test this hypothesis, we housed ducks in 2 barns, one with water lines and one with water troughs. Water troughs were constructed to meet RSPCA guidelines for number and density of ducks and with recently described verandas. Ducks were divided into 4 pens per barn (n=1,000 ducks/pen). The study was then repeated (n=8 pens per water source) in a cross-over design so the barns each contained the opposite water source to the first experiment. We scored the ducks' body condition using an established scoring rubric and analyzed using SAS Proc GLM-Mix as binomial data. Ducks housed with water troughs showed higher (thus worse condition; P<0.001) scores for eyes, nostrils, feather quality, feather cleanliness, and foot pads. We also compared water condition, water quality, and duck mortality using a Student t test for both water sources each week. We found that the water troughs showed higher iron (P<0.001), nitrites (P<0.001), pH (P<0.01), and bacterial growth (P<0.001). The bacterial growth was shown to have higher (P<0.001)E. coli, coliforms, and Staphylococcusin the water troughs. Water lines typically showed no bacterial growth in culture-based assays. Ducks housed with water troughs used greater (P=0.001) volumes of water compared to ducks housed with water lines. Ducks with water troughs also showed a greater percent (P=0.008) mortality at all ages compared to ducks with water lines. These data suggest that water troughs may not be beneficial for duck welfare and could adversely impact both environment and duck or human health. © The Author 2016. Published by Oxford University Press on behalf of Poultry Science Association.

Study on integration potential of gas turbines and gas engines into parabolic trough power plants

NASA Astrophysics Data System (ADS)

Vogel, Tobias; Oeljeklaus, Gerd; Görner, Klaus

2017-06-01

Hybrid power plants represent an important intermediate step on the way to an energy supply structure based substantially on renewable energies. Natural gas is the preferred fossil fuel for hybridization of solar thermal power plants, due to its low specific CO2-emission and technical advantages by means of integration into the power plant process. The power plant SHAMS ONE serves as an exemplary object of this study. In order to facilitate peaker gas turbines in an economical way to a combined cycle approach, with the SGT-400 an industrial gas turbine of the 10-20 MWel class have been integrated into the base case power plant. The concept has been set up, to make use of the gas turbine waste heat for power generation and increasing the overall power plant efficiency of the hybrid power plant at the same time. This concept represents an alternative to the widely used concept of combined cycle power plants with solar heat integration. Supplementary, this paper also dedicates the alternative to use gas engines instead of gas turbines.

Structural features related to the volcanic gases in Southern Okinawa Trough

NASA Astrophysics Data System (ADS)

Wang, H. F.; Hsu, S. K.; Tsia, C. H.; Chen, S. C.; Wu, M. F.

2016-12-01

The Okinawa Trough is a rifted back-arc basin, heavily sedimented and formed in an intracontinental rift zone behind the Ryukyu trench-arc system. The Southern Okinawa Trough (SOT) east of Taiwan is the place where post-collisional extension happened. The collision moved southwestward and the Ryukyu trench-arc extension westward, Arc volcanism is dominant in the Northern Ryukyu volcanic arc and back-arc volcanism in the Southern Okinawa Trough. Marine geophysical data including side-scan sonar (SSS), sub-bottom profiler (SBP) and echo sounder system (EK60) data are used in this study. Active fluid activities out of seafloor are obvious from various images observed on these data, such as gas plumes. These hydrothermal vents have been located at a water depth of 1400 m. Our preliminary results show that gas seepage structures appear in the location where is a week zone, such as a normal fault in the slope. The hydrothermal activity within the Okinawa Trough is associated with volcanism located in rift zones in the Southern Okinawa Trough. However, the origin of the submarine hydrothermal fluids within the Okinawa Trough is diverse with contributions from volcanic, sedimentary and magmatic sources, needed further investigations.

A V-band wafer probe using ridge-trough waveguide

NASA Astrophysics Data System (ADS)

Godshalk, Edward M.

1991-12-01

A V-band (50-75 GHz) wafer probe is presented. The probe features a type of waveguide developed to allow transition from rectangular waveguide to coplanar waveguide. The waveguide consists of a ridge extending from the upper waveguide wall into a trough in the lower waveguide wall, and is known as the ridge-trough waveguide. A mathematical model is presented that allows important properties of the ridge-trough waveguide, such as the cutoff frequency and characteristic impedance, to be calculated.

Developments in Marine Current Turbine Research at the United States Naval Academy (Invited)

NASA Astrophysics Data System (ADS)

Flack, K. A.; Luznik, L.

2013-12-01

A series of tests have been performed on a 1/25th scale model of a two bladed horizontal axis marine current turbine. The tests were conducted in a large tow tank facility at the United States Naval Academy. The turbine model has a 0.8 m diameter (D) rotor with a NACA 63-618 cross section, which is Reynolds number independent with respect to the lift coefficient in the operating range of Rec ≈ 4 x 105. Baseline test were conducted to obtain torque, thrust and rotational speed at a range of tip speed ratios (TSR) from 5 < TSR < 11. The power and thrust coefficients for the model turbine match expected results from blade-element-momentum theory. The lift and drag curves for the numerical model were obtained by testing a 2D NACA 63-618 airfoil in a wind tunnel. Additional tests were performed at two rotor depths (1.3D and 2.25D) in the presence of intermediate and deep water waves. The average values for power and thrust coefficient are weakly dependent on turbine depth. The waves yield a small increase in turbine performance which can be explained by Stokes drift velocity. Phase averaged results indicate that the oscillatory wave velocity results in significant variations in measured turbine torque and rotational speed as a function of wave phase. The turbine rotation speed, power, and thrust reach a maximum with the passing of the wave crest and a minimum with the passing of the wave trough. The torque appears dependent on vertical velocity, which lags the horizontal velocity by 90° of wave phase. Variations of the performance parameters are of the same order of magnitude as the average value, especially when the turbine is near the mean free surface and in the presence of high energy waves. These results demonstrate the impact of surface gravity waves on power production and structural loading. Future tests will focus on measuring and modeling the wake of the turbine for unsteady flow conditions. Model Turbine Power Coefficient vs, Tip Speed Ratio

Geophysical basin structure of the Cotonou (Dahomey/Benin) basin, West African Gulf of Guinea

DOE Office of Scientific and Technical Information (OSTI.GOV)

Babalola, O.O.

1990-05-01

The frontier Cotonou basin (or Dahomey/Benin embayment), situated west of the prolific Niger Delta basin, appears from seismic, gravity, and aeromagnetic interpretation, as a series of grabens and troughs confined on the west and east by the Romanche and the Chain fracture zones, respectively. The Keta trough of the western basin rim was formed by a 2700-m southeasterly downthrow of the Adina fault. This trough is separated by a north-northeasterly fault from the Lome-Anecho gravity high. Eastward, the arcuate Allada-Adjohon trough is abutted on its southern flank by the northwest-trending Nokue-Afowo trough and separated from the northwesterly Ikorodu trough bymore » the 50-km-wide aeromagnetically inferred ro-Otta ridge. The Ikorodu trough is adjoined on the northwest by the Aiyetoro trough and on the southeast by the Yemoja offshore graben trending east northeast as the Seme oil-field structural trend. North of the regional northeasterly axial, gravity positive, structural divide (the continental precursor of the Charcot fracture zone) a series of half-grabens (notably the Aplahoue, Bohicon, and Keiou troughs), normal faulted eastward and downthrown in the west, dominate the landward western rim of the Cotonou basin. Graben-bounding faults control the upper valleys of the basin drainage, converge toward the regional intrabasin structural trend and continue into the Fenyi-koe fault and the Charcot fracture zone. These faults resulted from brittle dextral shear of continental crust oblique to local, preexisting north-northeast structural trends. In the eastern basin rim, preexisting north-northwest structural trends influenced the shearing stress regime to generate small, shallow, structurally bounded, east-northeast- and north-northwest trending grabens.« less

Self-organized criticality in sandpiles - Nature of the critical phenomenon. [dynamic models in phase transition

NASA Technical Reports Server (NTRS)

Carlson, J. M.; Chayes, J. T.; Swindle, G. H.; Grannan, E. R.

1990-01-01

The scaling behavior of sandpile models is investigated analytically. First, it is shown that sandpile models contain a set of domain walls, referred to as troughs, which bound regions that can experience avalanches. It is further shown that the dynamics of the troughs is governed by a simple set of rules involving birth, death, and coalescence events. A simple trough model is then introduced, and it is proved that the model has a phase transition with the density of the troughs as an order parameter and that, in the thermodynamic limit, the trough density goes to zero at the transition point. Finally, it is shown that the observed scaling behavior is a consequence of finite-size effects.

Influence of trough versus pasture feeding on average daily gain and carcass characteristics in ruminants: a meta-analysis.

PubMed

Agastin, A; Sauvant, D; Naves, M; Boval, M

2014-03-01

Quantitative meta-analysis was run on 108 publications featuring 116 experiments and 399 treatments dealing with the effect of trough or pasture feeding environment (FE) on ruminant performances. The objective was to compare the effect of trough or pasture FE on ADG, diet OM digestibility (OMD), various carcass characteristics, and the interaction between FE and complementation modalities. Live weight was adjusted to compare results between species. Results showed that trough-fed animals had higher ADG (+17.89%; P < 0.001), hot carcass yield (HYield; + 2.47%; P < 0.001) and carcass fat content (+ 24.87%; P < 0.001) than pasture-fed animals but lower carcass muscle and bone percentages (-1.60% [P = 0.010] and -7.63% [P = 0.003], respectively). Feeding environment had no effect on diet OMD (P = 0.818), but the number of observations was low. After considering the addition or not of concentrate in the diet (addiCO), FE effect persisted on ADG (P = 0.024) and carcass fat content (P = 0.027) but not on HYield (P = 0.078) or muscle and bone percentages (P = 0.119 and P = 0.581, respectively). After considering the nature of the concentrate (natCO), FE effect persisted on ADG (P < 0.001) and HYield (P = 0.004). Considering the percentage of concentrate in the diet (PCO) erased FE effect on ADG (P = 0.891) and HYield (P = 0.128). In contrast, considering the quantity of concentrate(QCO) erased FE effect on ADG (P = 0.084) but not on HYield (P = 0.006) or on carcass fat and muscle contents (P = 0.040 and P = 0.040, respectively) although the FE effect on carcass bone content persisted (P = 0.550). Animal species and physiological stage had no effect on any of the variables studied (P > 0.05) but experiment did (P ≤ 0.001). The increase in ADG was positively correlated to HYield in cattle (P = 0.002) and small ruminants (P = 0.003) and positively linked to carcass fat content (P = 0.007) but not carcass muscle content, which actually decreased (P = 0.001). Overall, this meta-analysis confirmed previous reports of FE effects and revealed how the differences generally reported result from a confounding effect of FE and nature of the diet. Indeed, in most of the studies used, trough-fed animals were supplemented with concentrate whereas pasture-fed animals were not. This research also highlighted the fact that pasture-fed animals have the potential to achieve the same performances as trough-fed animals when fed a similar diet.

Environments of Long-Lived Mesoscale Convective Systems Over the Central United States in Convection Permitting Climate Simulations

NASA Astrophysics Data System (ADS)

Yang, Qing; Houze, Robert A.; Leung, L. Ruby; Feng, Zhe

2017-12-01

Continental-scale convection-permitting simulations of the warm seasons of 2011 and 2012 using the Weather Research and Forecasting model reproduce realistic structure and frequency distribution of lifetime and event mean precipitation of mesoscale convective systems (MCSs) over the central United States. Analysis is performed to determine the environmental conditions conducive to generating long-lived MCSs. The simulations show that MCSs systematically form over the central Great Plains ahead of a trough in the westerlies in combination with an enhanced low-level moist jet from the Gulf of Mexico. These environmental properties at the time of storm initiation are most prominent for the MCSs that persist for the longest times. MCSs reaching lifetimes of 9 h or more occur closer to the approaching trough than shorter-lived MCSs. These long-lived MCSs exhibit the strongest feedback to the environment through diabatic heating in the trailing regions of the MCSs. The feedback strengthens the synoptic-scale trough associated with the MCS by producing an anomaly circulation characterized by a divergent perturbation at high levels over the MCS and a midlevel cyclonic circulation perturbation near the trough line in association with the trailing portion of the MCS. The quasi-balanced mesoscale vortex may help to maintain the MCS over a long period of time by feeding dry, cool air into the environment at the rear of the MCS region that enhances evaporative cooling and helps maintain the MCS.

The impact of the structural features of the rock mass on seismicity in Polish coal mines

NASA Astrophysics Data System (ADS)

Patyńska, Renata

2017-11-01

The article presents seismic activity induced in the coal mines of the Upper Silesian Coal Basin (GZW) in relation to the locations of the occurrence of rockbursts. The comparison of these measurements with the structural features of the rock mass of coal mines indicates the possibility of estimating the so-called Unitary Energy Expenditure (UEE) in a specific time. The obtained values of UEE were compared with the distribution of seismic activity in GZW mines. The level of seismic activity in the analysed period changed and depended on the intensity of mining works and diverse mining and geological conditions. Five regions, where tremors occurred (Bytom Trough, Main Saddle, Main Trough, Kazimierz Trough, and Jejkowice and Chwałowice Trough) which belong to various structural units of the Upper Silesia were analyzed. It was found out that rock bursts were recorded only in three regions: Main Saddle, Bytom Trough, and Jejkowice and Chwałowice Trough.

Aero-acoustic Properties of Eroded Airfoils of Compressor Blades for Use in Non-invasive Diagnostics

NASA Astrophysics Data System (ADS)

Drãgan, Valeriu; Grad, Danuţa

2013-09-01

The current techniques for investigating the erosion of turbo machineries rely on visual inspections trough boroscopy. However this implies shutting down the power plant in order to make the assessment which leads to operational costs and difficulties. This paper aims to provide a method for monitoring the erosion state of a bladed power plant operated in dusty environments such as the desert by measuring the changes in its acoustic spectrum. The method used for this study is numerical and the findings suggest that there are significant modifications to both the flow field and the acoustic parameters as the blade gets progressively eroded. This paves the way for the development of non-invasive permanent real time diagnostics for turbine engines and power plants.

New operating strategies for molten salt in line focusing solar fields - Daily drainage and solar receiver preheating

NASA Astrophysics Data System (ADS)

Eickhoff, Martin; Meyer-Grünefeldt, Mirko; Keller, Lothar

2016-05-01

Nowadays molten salt is efficiently used in point concentrating solar thermal power plants. Line focusing systems still have the disadvantage of elevated heat losses at night because of active freeze protection of the solar field piping system. In order to achieve an efficient operation of line focusing solar power plants using molten salt, a new plant design and a novel operating strategy is developed for Linear Fresnel- and Parabolic Trough power plants. Daily vespertine drainage of the solar field piping and daily matutinal refilling of the solar preheated absorber tubes eliminate the need of nocturnal heating of the solar field and reduce nocturnal heat losses to a minimum. The feasibility of this new operating strategy with all its sub-steps has been demonstrated experimentally.

Preliminary operational results from the Willard solar power system

NASA Technical Reports Server (NTRS)

Fenton, D. L.; Abernathy, G. H.; Krivokapich, G.; Ellibee, D. E.; Chilton, V.

1980-01-01

The solar powered system located near Willard, New Mexico, generates mechanical or electrical power at a capacity of 19 kW (25 HP). The solar collection system incorporates east/west tracking parabolic trough collectors with a total aperture area of 1275 sq m (13,720 sq ft). The hot oil type thermal energy storage is sufficient for approximately 20 hours of power system operation. The system utilizes a reaction type turbine in conjunction with an organic Rankine cycle engine. Total collector field efficiency reaches a maximum of 20 percent near the winter solstice and about 50 percent during the summer. During the month of July, 1979, the system pumped 60 percent of the 35,300 cu m (28.6 acre-feet) of water delivered. Operating efficiencies for the turbine component, organic Rankine cycle engine and the complete power system are respectively 65 to 75 percent, 12 to 15 percent and 5 to 6 percent. Significant maintenance time was expended on both the collector and power systems throughout the operational period.

Preliminary operational results from the Willard solar power system

NASA Astrophysics Data System (ADS)

Fenton, D. L.; Abernathy, G. H.; Krivokapich, G.; Ellibee, D. E.; Chilton, V.

1980-05-01

The solar powered system located near Willard, New Mexico, generates mechanical or electrical power at a capacity of 19 kW (25 HP). The solar collection system incorporates east/west tracking parabolic trough collectors with a total aperture area of 1275 sq m (13,720 sq ft). The hot oil type thermal energy storage is sufficient for approximately 20 hours of power system operation. The system utilizes a reaction type turbine in conjunction with an organic Rankine cycle engine. Total collector field efficiency reaches a maximum of 20 percent near the winter solstice and about 50 percent during the summer. During the month of July, 1979, the system pumped 60 percent of the 35,300 cu m (28.6 acre-feet) of water delivered. Operating efficiencies for the turbine component, organic Rankine cycle engine and the complete power system are respectively 65 to 75 percent, 12 to 15 percent and 5 to 6 percent. Significant maintenance time was expended on both the collector and power systems throughout the operational period.

Stress Fields Along Okinawa Trough and Ryukyu Arc Inferred From Regional Broadband Moment Tensors

NASA Astrophysics Data System (ADS)

Kubo, A.; Fukuyama, E.

2001-12-01

Most shallow earthquakes along Okinawa trough and Ryukyu arc are relatively small (M<5.5). Focal mechanism estimations for such events were difficult due to insufficient dataset. However, this situation is improved by regional broadband network (FREESIA). Lower limit of magnitude of the earthquakes determined becomes 1.5 smaller in M{}w than that of Harvard moment tensors. As a result, we could examine the stress field in more detail than Fournier et al.(2001, JGR, 106, 13751-) did based on surface geology and teleseismic moment tensors. In the NE Okinawa trough, extension axes are oblique to the trough strike, while in SW Okinawa trough, they are perpendicular to the trough. Fault type in SW is normal fault and gradually changes to mixture of normal and strike slip toward NE. In the Ryukyu arc, extension axes are parallel to the arc. Although this feature is not clear in the NW Ryukyu arc, arc parallel extension may be a major property of entire arc. Dominant fault type is normal fault and several strike slips with the same extensional component are included. The volcanic train is located at the edge of arc parallel extension field faced A simple explanation of the arc parallel extension is the response to the opening motion of the Okinawa trough. Another possible mechanism is forearc movement due to oblique subduction which is enhanced in SW. We consider that the Okinawa trough and the Ryukyu arc are independent stress provinces.

Projection of distributed-collector solar-thermal electric power plant economics to years 1990-2000

NASA Technical Reports Server (NTRS)

Fujita, T.; Elgabalawi, N.; Herrera, G.; Turner, R. H.

1977-01-01

A preliminary comparative evaluation of distributed-collector solar thermal power plants was undertaken by projecting power plant economics of selected systems to the 1990 to 2000 time frame. The selected systems include: (1) fixed orientation collectors with concentrating reflectors and vacuum tube absorbers, (2) one axis tracking linear concentrator including parabolic trough and variable slat designs, and (3) two axis tracking parabolic dish systems including concepts with small heat engine-electric generator assemblies at each focal point as well as approaches having steam generators at the focal point with pipeline collection to a central power conversion unit. Comparisons are presented primarily in terms of energy cost and capital cost over a wide range of operating load factors. Sensitvity of energy costs for a range of efficiency and cost of major subsystems/components is presented to delineate critical technological development needs.

Rankline-Brayton engine powered solar thermal aircraft

DOEpatents

Bennett, Charles L [Livermore, CA

2012-03-13

A solar thermal powered aircraft powered by heat energy from the sun. A Rankine-Brayton hybrid cycle heat engine is carried by the aircraft body for producing power for a propulsion mechanism, such as a propeller or other mechanism for enabling sustained free flight. The Rankine-Brayton engine has a thermal battery, preferably containing a lithium-hydride and lithium mixture, operably connected to it so that heat is supplied from the thermal battery to a working fluid. A solar concentrator, such as reflective parabolic trough, is movably connected to an optically transparent section of the aircraft body for receiving and concentrating solar energy from within the aircraft. Concentrated solar energy is collected by a heat collection and transport conduit, and heat transported to the thermal battery. A solar tracker includes a heliostat for determining optimal alignment with the sun, and a drive motor actuating the solar concentrator into optimal alignment with the sun based on a determination by the heliostat.

Rankine-Brayton engine powered solar thermal aircraft

DOEpatents

Bennett, Charles L [Livermore, CA

2009-12-29

A solar thermal powered aircraft powered by heat energy from the sun. A Rankine-Brayton hybrid cycle heat engine is carried by the aircraft body for producing power for a propulsion mechanism, such as a propeller or other mechanism for enabling sustained free flight. The Rankine-Brayton engine has a thermal battery, preferably containing a lithium-hydride and lithium mixture, operably connected to it so that heat is supplied from the thermal battery to a working fluid. A solar concentrator, such as reflective parabolic trough, is movably connected to an optically transparent section of the aircraft body for receiving and concentrating solar energy from within the aircraft. Concentrated solar energy is collected by a heat collection and transport conduit, and heat transported to the thermal battery. A solar tracker includes a heliostat for determining optimal alignment with the sun, and a drive motor actuating the solar concentrator into optimal alignment with the sun based on a determination by the heliostat.

A novel method for predicting the power outputs of wave energy converters

NASA Astrophysics Data System (ADS)

Wang, Yingguang

2018-03-01

This paper focuses on realistically predicting the power outputs of wave energy converters operating in shallow water nonlinear waves. A heaving two-body point absorber is utilized as a specific calculation example, and the generated power of the point absorber has been predicted by using a novel method (a nonlinear simulation method) that incorporates a second order random wave model into a nonlinear dynamic filter. It is demonstrated that the second order random wave model in this article can be utilized to generate irregular waves with realistic crest-trough asymmetries, and consequently, more accurate generated power can be predicted by subsequently solving the nonlinear dynamic filter equation with the nonlinearly simulated second order waves as inputs. The research findings demonstrate that the novel nonlinear simulation method in this article can be utilized as a robust tool for ocean engineers in their design, analysis and optimization of wave energy converters.

Trough Coating Solar Cells Without Spillover

NASA Technical Reports Server (NTRS)

Heaps, J. D.

1986-01-01

Problem with trough coating of silicon on ceramic - spillover of molten silicon - overcome by combination of redesigned heaters and tiltable trough. Modifications make it possible to coat virtually any length of ceramic with film of solar-cell-grade silicon. Previously, maximum length coated before spillover occurred was 2 inches (5.1 cm).

Labeatis Trough

NASA Technical Reports Server (NTRS)

2006-01-01

2 July 2006 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a portion of a trough cutting across a dust-covered plain in the Labeatis Fossae region of Mars. Boulders derived from the layered exposures near the top of the trough walls are resting on the floor, and in some locations, the sloping sidewalls of the dusty trough.

Location near: 22.1oN, 94.5oW Image width: 3 km (1.9 mi) Illumination from: lower left Season: Northern Spring

Pennsylvanian-Permian tectonism in the Great Basin: The Dry Mountain trough and related basins

DOE Office of Scientific and Technical Information (OSTI.GOV)

Snyder, W.S.; Spinosa, C.; Gallegos, D.M.

1991-02-01

Pennsylvanian-Permian tectonism affected the continental margin of western North America from the Yukon to the Mojave Desert. Specific signatures of this tectonism include local angular unconformities, regional disconformities, renewed outpouring of clastic debris from a reactivated Antler and related highlands, and development of deeper water basins with anoxic sediments deposited below wave base. The basins formed include Ishbel trough (Canada), the Wood River basin (Idaho), Cassia basin, Ferguson trough, Dry Mountain trough (all Nevada), and unnamed basins in Death Valley-Mojave Desert region. The Dry Mountain trough (DMT) was initiated during early Wolfcampian and received up to 1,200 m of sedimentmore » by the late Leonardian. The lower contact is a regional unconformity with the Ely Limestone, or locally with the Diamond Peak or Vinini formations. Thus, following a period of localized regional uplift that destroyed the Ely basin, portions of the uplifted and exposed shelf subsided creating the Dry Mountain trough. Evidence suggesting a tectonic origin for the DMT includes (1) high subsidence rates (60-140 m/m.y.); (2) renewed influx of coarse clastic debris from the Antler highlands: (3) possible pre-Early Permian folding, thrusting, and tilting within the highlands; and (4) differential subsidence within the Dry Mountain trough, suggesting the existence of independent fault blocks.« less

Present-day erosion of Martian polar terrain by the seasonal CO2 jets

NASA Astrophysics Data System (ADS)

Portyankina, Ganna; Hansen, Candice J.; Aye, Klaus-Michael

2017-01-01

Here we report on the detection of new dendritic troughs created by the seasonal CO2 jet activity over several Martian years. According to Kieffers hypothesis (Kieffer, 2007) in Martian polar areas seasonal CO2 ice sublimation creates gas jets that deposit fans of mineral dust and sand on top of the CO2 ice. These jets and the related sub-ice gas flows are believed to carve troughs in the underlying polar deposits which, after multiple repetitions of this process throughout Martian spring seasons, create araneiform terrains. The High Resolution Imaging Science Experiment (HiRISE) on the Mars Reconnaissance Orbiter (MRO) detected the new troughs during its campaign for seasonal monitoring of the polar areas. The newly detected dendritic troughs are small shallow branching troughs (≈ 1.4 m wide) similar to the seasonal furrows previously detected in the northern hemisphere (Bourke, 2013). The essential difference between the new troughs and furrows lies in the fact that the troughs in the south are persistent while the northern furrows are erased each Martian year by the sand movement due to summer winds. From year to year the new southern troughs extend and develop new tributaries and their overall geometry turns from linear to dendritic, a characteristic shared with araneiform terrains. We believe that furrows have the same origin as the southern dendritic troughs but do not develop into dendritic shapes because of the high mobility of the dune material into which they are carved. Several locations where new dendritic troughs are observed lie in the vicinity of dunes. This gives us an observational indication that presence of erosive sand material is an important factor in creating (or at least starting) erosive processes that lead to the formation of dendritic troughs. By extrapolation the same mechanism should be acting to create the much larger araneiform terrains. Detection of the present day erosion working in polar areas and creating new topographical features is important for understanding of the processes that shape polar areas. Several years of HiRISE observations provide us with the information about the current rate of erosion and hence help estimate minimum ages of the araneiforms and the surface into which they are carved to be 1.3 × 103 Martian years.

SolarTherm: A flexible Modelica-based simulator for CSP systems

NASA Astrophysics Data System (ADS)

Scott, Paul; Alonso, Alberto de la Calle; Hinkley, James T.; Pye, John

2017-06-01

Annual performance simulations provide a valuable tool for analysing the viability and overall impact of different concentrating solar power (CSP) component and system designs. However, existing tools work best with conventional systems and are difficult or impossible to adapt when novel components, configurations and operating strategies are of interest. SolarTherm is a new open source simulation tool that fulfils this need for the solar community. It includes a simulation framework and a library of flexible CSP components and control strategies that can be adapted or replaced with new designs to meet the special needs of end users. This paper provides an introduction to SolarTherm and a comparison of models for an energy-based trough system and a physical tower system to those in the well-established and widely-used simulator SAM. Differences were found in some components where the inner workings of SAM are undocumented or not well understood, while the other parts show strong agreement. These results help to validate the fundamentals of SolarTherm and demonstrate that, while at an early stage of development, it is already a useful tool for performing annual simulations.

Efficacy and Mechanisms of Action of Fecal Microbiota Transplantation in Ulcerative Colitis: Pitfalls and Promises From a First Meta-Analysis.

PubMed

Scaldaferri, F; Pecere, S; Petito, V; Zambrano, D; Fiore, L; Lopetuso, L R; Schiavoni, E; Bruno, G; Gerardi, V; Laterza, L; Pizzoferrato, M; Ianiro, G; Stojanovic, J; Poscia, A; Papa, A; Paroni Sterbini, F; Sanguinetti, M; Masucci, L; Cammarota, G; Gasbarrini, A

2016-03-01

Inflammatory bowel disease (IBD) is the results of a chronic inflammatory process deriving from disequilibrium between self-microbiota composition and immune response. New evidence, coming from Clostridium difficile infection, clearly showed that active and powerful modulation of microbiota composition by fecal microbiota composition (FMT) is safe, easy to perform, and efficacious, opening new frontiers in gastrointestinal and extra-intestinal diseases. FMT has been proposed also for IBD as well as other non-gastrointestinal conditions related to intestinal microbiota dysfunctions, with good preliminary data. In this setting, ulcerative colitis (UC) represents one of the most robust potential indications for FMT after C difficile colitis. In the present review, we focus on FMT and its application on ulcerative colitis, clarifying mechanisms of actions and efficacy data, trough completion of a meta-analysis on available randomized, controlled trial data in UC. Because microbiota is so crucially involved in this topic, a short review of microbial alterations in UC will also be performed. Copyright © 2016 Elsevier Inc. All rights reserved.

A Geospatial Comparison of Distributed Solar Heat and Power in Europe and the US

PubMed Central

Norwood, Zack; Nyholm, Emil; Otanicar, Todd; Johnsson, Filip

2014-01-01

The global trends for the rapid growth of distributed solar heat and power in the last decade will likely continue as the levelized cost of production for these technologies continues to decline. To be able to compare the economic potential of solar technologies one must first quantify the types and amount of solar resource that each technology can utilize; second, estimate the technological performance potential based on that resource; and third, compare the costs of each technology across regions. In this analysis, we have performed the first two steps in this process. We use physical and empirically validated models of a total of 8 representative solar system types: non-tracking photovoltaics, 2d-tracking photovoltaics, high concentration photovoltaics, flat-plate thermal, evacuated tube thermal, concentrating trough thermal, concentrating solar combined heat and power, and hybrid concentrating photovoltaic/thermal. These models are integrated into a simulation that uses typical meteorological year weather data to create a yearly time series of heat and electricity production for each system over 12,846 locations in Europe and 1,020 locations in the United States. Through this simulation, systems composed of various permutations of collector-types and technologies can be compared geospatially and temporally in terms of their typical production in each location. For example, we see that silicon solar cells show a significant advantage in yearly electricity production over thin-film cells in the colder climatic regions, but that advantage is lessened in regions that have high average irradiance. In general, the results lead to the conclusion that comparing solar technologies across technology classes simply on cost per peak watt, as is usually done, misses these often significant regional differences in annual performance. These results have implications for both solar power development and energy systems modeling of future pathways of the electricity system. PMID:25474632

A geospatial comparison of distributed solar heat and power in Europe and the US.

PubMed

Norwood, Zack; Nyholm, Emil; Otanicar, Todd; Johnsson, Filip

2014-01-01

The global trends for the rapid growth of distributed solar heat and power in the last decade will likely continue as the levelized cost of production for these technologies continues to decline. To be able to compare the economic potential of solar technologies one must first quantify the types and amount of solar resource that each technology can utilize; second, estimate the technological performance potential based on that resource; and third, compare the costs of each technology across regions. In this analysis, we have performed the first two steps in this process. We use physical and empirically validated models of a total of 8 representative solar system types: non-tracking photovoltaics, 2d-tracking photovoltaics, high concentration photovoltaics, flat-plate thermal, evacuated tube thermal, concentrating trough thermal, concentrating solar combined heat and power, and hybrid concentrating photovoltaic/thermal. These models are integrated into a simulation that uses typical meteorological year weather data to create a yearly time series of heat and electricity production for each system over 12,846 locations in Europe and 1,020 locations in the United States. Through this simulation, systems composed of various permutations of collector-types and technologies can be compared geospatially and temporally in terms of their typical production in each location. For example, we see that silicon solar cells show a significant advantage in yearly electricity production over thin-film cells in the colder climatic regions, but that advantage is lessened in regions that have high average irradiance. In general, the results lead to the conclusion that comparing solar technologies across technology classes simply on cost per peak watt, as is usually done, misses these often significant regional differences in annual performance. These results have implications for both solar power development and energy systems modeling of future pathways of the electricity system.

Verification of the modelling of the main ionospheric trough by the Electron Density Assimilative Model (EDAM)

NASA Astrophysics Data System (ADS)

Parker, James; Pryse, Eleri; Jackson-Booth, Natasha

2017-04-01

The main ionospheric trough is a large-scale spatial depletion in the ionospheric electron density that commonly separates the auroral and mid-latitude regions. The feature covers several degrees in latitude and is extended in longitude. It exhibits substantial day-to-day variability in both the location of its minimum ionisation density and in its latitudinal structure. Observations from the UK have shown the trough to be a night-time feature, appearing in early evening to the north of the mainland and progressing equatorward during the course of the night. At dawn, photoionisation fills in the feature. Under increasing levels of geomagnetic activity, the trough moves progressively to lower latitudes. Steep gradients on the trough walls and their variability can cause problems for radio applications. EDAM can be used to model the ionosphere at the trough latitudes by assimilating ionospheric observations from this region into the International Reference Ionosphere (IRI). In this study troughs modelled by EDAM, assimilating data for a period from September to December 2002, are presented and are verified by comparisons with independent observations. Measurements of slant total electron content (sTEC) between GPS satellites and forty ground receivers in Europe were assimilated into EDAM to model the ionospheric electron density. The Vertical Total Electron Content (VTEC) was then calculated through the model, with the values at the longitude of 0.0E considered to obtain statistical characteristics of identified troughs parameters. Comparisons of the parameters with those obtained previously, using transmissions from the satellites of NIMS (Navy Ionospheric Monitoring System) orbiting at altitudes lower than GPS, revealed consistent results. Further support for the EDAM trough was obtained by comparisons of the model with independent GPS measurements. For this a GPS ground station not used in the assimilation was used to observe the sTEC to this "truth" station. Comparisons of these independent truth data with sTEC calculated through the model were used to determine the accuracy of EDAM in the vicinity of the trough.

Merging and energy exchange between optical filaments

NASA Astrophysics Data System (ADS)

Georgieva, D. A.; Kovachev, L. M.

2015-10-01

We investigate nonlinear interaction between collinear femtosecond laser pulses with power slightly above the critical for self-focusing Pcr trough the processes of cross-phase modulation (CPM) and degenerate four-photon parametric mixing (FPPM). When there is no initial phase difference between the pulses we observe attraction between pulses due to CPM. The final result is merging between the pulses in a single filament with higher power. By method of moments it is found that the attraction depends on the distance between the pulses and has potential character. In the second case we study energy exchange between filaments. This process is described through FPPM scheme and requests initial phase difference between the waves.

Merging and energy exchange between optical filaments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Georgieva, D. A., E-mail: dgeorgieva@tu-sofia.bg; Kovachev, L. M.

2015-10-28

We investigate nonlinear interaction between collinear femtosecond laser pulses with power slightly above the critical for self-focusing P{sub cr} trough the processes of cross-phase modulation (CPM) and degenerate four-photon parametric mixing (FPPM). When there is no initial phase difference between the pulses we observe attraction between pulses due to CPM. The final result is merging between the pulses in a single filament with higher power. By method of moments it is found that the attraction depends on the distance between the pulses and has potential character. In the second case we study energy exchange between filaments. This process is describedmore » through FPPM scheme and requests initial phase difference between the waves.« less

Topography and Stratigraphy of the Northern Martian Polar Layered Deposits Using Photoclinometry, Stereogrammetry, and MOLA Altimetry

USGS Publications Warehouse

Fenton, L.K.; Herkenhoff, K. E.

2000-01-01

We present two photoclinometric profiles across a trough in the martian northern polar layered terrain. Complications caused by albedo variations were avoided by using an early springtime Viking image with a thin cover of seasonal CO2 frost. The topographic profiles were constrained with stereogrammetric elevations derived from summertime Viking images of the same region. We find that the photoclinometric profiles are consistent with a nearby MOLA (Mars Orbiter Laser Altimeter) track crossing the same polar trough. The trough is asymmetric, with higher relief and a steeper slope on the equatorward-facing wall. Individual layers are subdued and difficult to observe in the profiles. A decrease in both relief and elevation toward the eastern end of the trough suggests that layers become thinner to the east. Declining equatorward slopes in the eastern portion of the trough imply that erosion rates have varied along the trough. The variation in erosion rate may be linked to the change in layer thickness along the trough. Layers have an average thickness of 19??8 m in the center of the trough and 59??32 m on the northern wall. The northern wall is most likely composed of thinner layers that are obscured. To first order, we find that a 19-m layer requires 16,000 years of deposition to form. Although this timescale does not coincide with orbital variation periods of 105 and 106 years, deposition rates may not be constant and thus the 16,000-year layer formation time does not preclude layer formation during part of each orbital oscillation. ?? 2000 Academic Press.

Meta-analysis of medical intervention for normal tension glaucoma.

PubMed

Cheng, Jin-Wei; Cai, Ji-Ping; Wei, Rui-Li

2009-07-01

To evaluate the intraocular pressure (IOP) reduction achieved by the most frequently prescribed antiglaucoma drugs in patients with normal tension glaucoma (NTG). Systematic review and meta-analysis. Fifteen randomized clinical trials reported 25 arms for peak IOP reduction, 16 arms for trough IOP reduction, and 13 arms for diurnal curve IOP reduction. Pertinent publications were identified through systematic searches of PubMed, EMBASE, and the Cochrane Controlled Trials Register. The patients had to be diagnosed as having NTG. Methodological quality was assessed by the Delphi list on a scale from 0 to 18. The pooled 1-month IOP-lowering effects were calculated using the 2-step DerSimonian and Laird estimate method of the random effects model. Absolute and relative reductions in IOP from baseline for peak and trough moments. Quality scores of included studies were generally high, with a mean quality score of 12.7 (range, 9-16). Relative IOP reductions were peak, 15% (12%-18%), and trough, 18% (8%-27%) for timolol; peak, 14% (8%-19%), and trough, 12% (-7% to 31%) for dorzolamide; peak, 24% (17%-31%), and trough, 11% (7%-14%) for brimonidine; peak, 20% (17%-24%), and trough, 20% (18%-23%) for latanoprost; peak, 21% (16%-25%), and trough, 18% (14%-22%) for bimatoprost. The differences in absolute IOP reductions between prostaglandin analogues and timolol varied from 0.9 to 1.0 mmHg at peak and -0.1 to 0.2 mmHg at trough. Latanoprost, bimatoprost, and timolol are the most effective IOP-lowering agents in patients with NTG.

Development and evaluation of a prototype concentrating solar collector with thermocline based thermal energy storage for residential thermal usage

DOE PAGES

Kumar, Vinod; Afrin, Samia; Ortega, Jesus; ...

2013-09-01

A prototype of a concentrating solar collector (CSC) receiver was designed, built, and evaluated on-sun at the University of Texas at El Paso in El Paso, TX. This prototype receiver consists of two parabolic trough-reflectors but, in principle, the design can be efficiently extended to multiple units for achieving a higher temperature throughput. Each reflector has a vacuum tube collector at the focal point of the trough. The solar collector system was combined with a single-tank thermocline thermal energy storage (TES) for off-solar thermal usage. The main goal of this study is to develop an advanced solar hot water systemmore » for most residential applications. The focus of this study is to investigate the feasibility and performance of the solar thermal system by employing the recent advancement in the TES—a thermocline based TES—system for the concentrating solar power technologies developed by the Sandia National Laboratories and National Renewable Energy Laboratories for electricity production. A CSC when combined with TES has potential to provide uninterrupted thermal energy for most residential usages. This paper presents a detailed description of prototype design and materials required. The thermal energy storage tank utilizes an insulated 170 l (45 gal) galvanized steel tank. In order to maintain thermocline in the TES tank, with hot water on top and cold water at the bottom, two plate distributors are installed in the tank. The data showed a significant enhancement in thermal energy generation. This thermocline based single tank presented a thermal energy storage potential for at least three days (with diminishing storage capacity) that test were performed. The whole prototype was made for approximately USD 355 (excludes any labor costs) and hence also has strong potential for supplying clean thermal energy in most developing countries. As a result, tests of the prototype were conducted in November 2011.« less

9 CFR 82.21 - Vehicles, cages, coops, containers, troughs, and other equipment used for infected poultry.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., troughs, and other equipment used for infected poultry. 82.21 Section 82.21 Animals and Animal Products... ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS EXOTIC NEWCASTLE DIS- EASE (END) AND CHLAMYDIOSIS Chlamydiosis in Poultry § 82.21 Vehicles, cages, coops, containers, troughs, and other equipment used for...

Evolution of the Outflows in NGC 3516

NASA Astrophysics Data System (ADS)

Dunn, Jay P.; Parvaresh, Rozhin; Kraemer, S. B.; Crenshaw, D. Michael

2018-02-01

We analyze the 2011 HST/COS spectrum of the Seyfert 1 galaxy NGC 3516, which demonstrates clear changes in one of the intrinsic absorption troughs (component 5), slight evidence of change in a second trough (component 6), and the appearance of a new absorption trough (component 9). We interpret both the changes and the appearance of the new trough as bulk motion across the line of sight. The implied lower limit on the transverse velocity of component 5 is 360 km s‑1, compared to the earlier 2001 HST/STIS spectrum, while the lower limits for components 6 and 9 are 920 km s‑1, based on 2009 FUSE data. Component 5 also exhibits a shift in velocity centroid. This is only the second known case of this behavior in a Seyfert galaxy. Due to the high quality of the HST/COS spectrum, we identify a previously undetected trough due to an excited state of Si II for component 1. In combination with the resonance trough of Si II and photoionization modeling, we directly determine the distance of the component 1 outflow to be 67.2 pc.

Prediction of Vancomycin Dose for Recommended Trough Concentrations in Pediatric Patients With Cystic Fibrosis.

PubMed

Amin, Raid W; Guttmann, Rodney P; Harris, Quianna R; Thomas, Janesha W

2018-05-01

Vancomycin is a key antibiotic used in the treatment of multiple conditions including infections associated with cystic fibrosis and methicillin-resistant Staphylococcus aureus. The present study sought to develop a model based on empirical evidence of optimal vancomycin dose as judged by clinical observations that could accelerate the achievement of desired trough level in children with cystic fibrosis. Transformations of dose and trough were used to arrive at regression models with excellent fit for dose based on weight or age for a target trough. Results of this study indicate that the 2 proposed regression models are robust to changes in age or weight, suggesting that the daily dose on a per-kilogram basis is determined primarily by the desired trough level. The results show that to obtain a vancomycin trough level of 20 μg/mL, a dose of 80 mg/kg/day is needed. This analysis should improve the efficiency of vancomycin usage by reducing the number of titration steps, resulting in improved patient outcome and experience. © 2018, The American College of Clinical Pharmacology.

Geochemical and Sr-Nd-Pb-Li isotopic characteristics of volcanic rocks from the Okinawa Trough: Implications for the influence of subduction components and the contamination of crustal materials

NASA Astrophysics Data System (ADS)

Guo, Kun; Zhai, Shikui; Yu, Zenghui; Wang, Shujie; Zhang, Xia; Wang, Xiaoyuan

2018-04-01

The Okinawa Trough is an infant back-arc basin developed along the Ryukyu arc. This paper provides new major and trace element and Sr-Nd-Pb-Li isotope data of volcanic rocks in the Okinawa Trough and combines the published geochemical data to discuss the composition of magma source, the influence of subduction component, and the contamination of crustal materials, and calculate the contribution between subduction sediment and altered oceanic crust in the subduction component. The results showed that there are 97% DM and 3% EMI component in the mantle source in middle trough (MS), which have been influenced by subduction sediment. The Li-Nd isotopes indicate that the contribution of subduction sediment and altered oceanic crust in subduction component are 4 and 96%, respectively. The intermediate-acidic rocks suffer from contamination of continental crust material in shallow magma chamber during fractional crystallization. The acidic rocks in south trough have experienced more contamination of crustal material than those from the middle and north trough segments.

The noon and midnight mid-latitude trough as seen by Ariel 4

NASA Technical Reports Server (NTRS)

Tulunay, Y. K.; Grebowsky, J. M.

1978-01-01

The electron density data returned by the polar orbiting satellites Ariel 3 and Ariel 4 revealed that the midlatitude trough is one of the distinct large-scale features of the ionosphere at about 550 km. Recent work (e.g., Tulunay and Grebowsky, 1975) on the data included the investigation of the temporal development of the latitudinal position of the midlatitude electron density trough at dawn and dusk during the large magnetic storms of May 1967 and May 1972. Model calculations which assumed that the equatorial convection E-field varies in step with the Kp index reproduced on the average the observed behavior. In the present paper, trough observations made at noon and midnight during the period, 12-21 December 1971 which encompassed a relatively large magnetic storm are discussed. In this context, model calculations have been employed as a guide of average approximations of the actual situation in predicting the plasmapause location. It is also shown that the trough observed on the noon passes is not generally plasmapause-related as the nightside troughs are expected to be.

Interference of Locally Forced Internal Waves in Non-Uniform Stratifications

NASA Astrophysics Data System (ADS)

Supekar, Rohit; Peacock, Thomas

2017-11-01

Several studies have investigated the effect of constructive or destructive interference on the transmission of internal waves propagating through non-uniform stratifications. Such studies have been performed for internal waves that are spatiotemporally harmonic. To understand the effect of localization, we perform a theoretical and experimental study of the transmission of two-dimensional internal waves that are generated by a spatiotemporally localized boundary forcing. This is done by considering an idealized problem and applying a weakly viscous semi-analytic linear model. Parametric studies using this model show that localization leads to the disappearance of transmission peaks and troughs that would otherwise be present for a harmonic forcing. Laboratory experiments that we perform provide a clear indication of this physical effect. Based on the group velocity and angle of propagation of the internal waves, a practical criteria that assesses when the transmission peaks or troughs are evident, is obtained. It is found that there is a significant difference in the predicted energy transfer due to a harmonic and non-harmonic forcing which has direct implications to various physical forcings such as a storm over the ocean.

Progress on the Ram Wing Concept with Emphasis on Lateral Dynamics

DOT National Transportation Integrated Search

1971-01-01

Theoretical and experimental efforts conducted at the Transportation Systems Center in the ram wing program are described. Glide Tests were performed using a simple ram wing model operating in an open rectangular trough 50 ft long. Lift drag ratios o...

Impact of ABCB1, ABCG2, and CYP3A5 polymorphisms on plasma trough concentrations of apixaban in Japanese patients with atrial fibrillation.

PubMed

Ueshima, Satoshi; Hira, Daiki; Fujii, Ryo; Kimura, Yuuma; Tomitsuka, Chiho; Yamane, Takuya; Tabuchi, Yohei; Ozawa, Tomoya; Itoh, Hideki; Horie, Minoru; Terada, Tomohiro; Katsura, Toshiya

2017-09-01

During anticoagulant therapy, major bleeding is one of the most severe adverse effects. This study aimed to evaluate the relationships between ABCB1, ABCG2, and CYP3A5 polymorphisms and plasma trough concentrations of apixaban, a direct inhibitor of coagulation factor X. A total of 70 plasma concentrations of apixaban from 44 Japanese patients with atrial fibrillation were analyzed. In these analyses, the plasma trough concentration/dose (C/D) ratio of apixaban was used as a pharmacokinetic index and all data were stratified according to the presence of ABCB1 (ABCB1 1236C>T, 2677G>T/A, and 3435C>T), ABCG2 (ABCG2 421C>A), and CYP3A5 (CYP3A5*3) polymorphisms. Influences of various clinical laboratory parameters (age, serum creatinine, estimated glomerular filtration rate, aspartate amino transferase, and alanine amino transferase) on the plasma trough C/D ratio of apixaban were included in analyses. Although no ABCB1 polymorphisms affected the plasma trough C/D ratio of apixaban, the plasma trough C/D ratio of apixaban was significantly higher in patients with the ABCG2 421A/A genotype than in patients with the ABCG2 421C/C genotype (P<0.01). The plasma trough C/D ratio of apixaban in patients with CYP3A5*1/*3 or *3/*3 genotypes was also significantly higher than that in patients with the CYP3A5*1/*1 genotype (P<0.05). Furthermore, the plasma trough C/D ratio of apixaban decreased with increased estimated glomerular filtration rate. These results indicate that ABCG2 421A/A and CYP3A5*3 genotypes and renal function are considered potential factors affecting trough concentrations of apixaban.

A digital map of the high center (HC) and low center (LC) polygon boundaries delineated from high resolution LiDAR data for Barrow, Alaska

DOE Data Explorer

Gangodagamage, Chandana; Wullschleger, Stan

2014-07-03

This dataset represent a map of the high center (HC) and low center (LC) polygon boundaries delineated from high resolution LiDAR data for the arctic coastal plain at Barrow, Alaska. The polygon troughs are considered as the surface expression of the ice-wedges. The troughs are in lower elevations than the interior polygon. The trough widths were initially identified from LiDAR data, and the boundary between two polygons assumed to be located along the lowest elevations on trough widths between them.

Benefits of full scope simulators during solar thermal power plants design and construction

NASA Astrophysics Data System (ADS)

Gallego, José F.; Gil, Elena; Rey, Pablo

2017-06-01

In order to efficiently develop high-precision dynamic simulators for solar thermal power plants, Tecnatom adapted its simulation technology to consider solar thermal models. This effort and the excellent response of the simulation market have allowed Tecnatom to develop simulators with both parabolic trough and solar power tower technologies, including molten salt energy storage. These simulators may pursue different objectives, giving rise to training or engineering simulators. Solar thermal power market combines the need for the training of the operators with the potential benefits associated to the improvement of the design of the plants. This fact along with the simulation capabilities enabled by the current technology and the broad experience of Tecnatom present the development of an engineering+training simulator as a very advantageous option. This paper describes the challenge of the development and integration of a full scope simulator during the design and construction stages of a solar thermal power plant, showing the added value to the different engineering areas.

Target organ damage in primary hypertensive patients: role of the morning heart rate surge.

PubMed

Zhan, Yuliang; Kang, Ting; Wei, Yunfeng

The morning heart rate surge (MHRS) and morning blood pressure surge (MBPS) may be responsible for the high prevalence of cardiovascular events during the morning period. The clinical significance of the MBPS has been well established, but that of the MHRS remains unclear. Thus, we evaluated the association between the MHRS and target organ damage (TOD). A cross-sectional study of 580 hypertensive patients was performed. MHRS and heart rate variability (HRV) were analyzed by 24 h electrocardiogram. TOD was assessed by estimated glomerular filtration rate, carotid intima-media thickness (IMT), and left ventricular mass index. The prevalence of TOD tended to decrease with sleep-trough MHRS (first to fourth quartiles: 71%, 70.3%, 58.6%, and 52.7%, respectively) or prewaking MHRS quartiles (first to fourth quartiles: 65.3%, 73.6%, 61.4%, and 54.2%, respectively), whereas the opposite trend was observed for standard deviation of all normal NN intervals (SDNN). Moreover, sleep-trough MHRS, prewaking MHRS, SDNN, and SDNN index were significantly lower in patients with TOD than in those without TOD. According to four logistic regression models, the associations of prewaking MHRS, SDNN, and SDNN index with TOD were lost after adjustment for age and BP. Patients in the first (≤11.125 bpm) and second sleep-trough MHRS quartiles (11.125-15.75 bpm) had a 1.95-2.06-fold increased risk of TOD compared with those in the fourth quartile (p < 0.05). A blunted sleep-trough MHRS, which may serve as a surrogate marker for autonomic imbalance, was independently associated with TOD in primary hypertensive patients.

Sedimentation and tectonics of the Sylhet trough, Bangladesh

USGS Publications Warehouse

Johnson, S.Y.; Nur Alam, A.M.

1991-01-01

The Sylhet trough, a sub-basin of the Bengal Basin in northeastern Bangladesh, contains a thick fill (12 to 16 km) of late Mesozoic and Cenozoic strata that record its tectonic evolution. Stratigraphic, sedimentologic, and petrographic data collected from outcrops, cores, well logs, and seismic lines are used to reconstruct the history of this trough. -from Authors

Numerical Optimization Using Desktop Computers

DTIC Science & Technology

1980-09-11

concentrating compound parabolic trough solar collector . Thermophysical, geophysical, optical and economic analyses were used to compute a life-cycle...third computer program, NISCO, was developed to model a nonimaging concentrating compound parabolic trough solar collector using thermophysical...concentrating compound parabolic trough Solar Collector . C. OBJECTIVE The objective of this thesis was to develop a system of interactive programs for the Hewlett

Self-pressurizing Stirling engine

DOEpatents

Bennett, Charles L.

2010-10-12

A solar thermal powered aircraft powered by heat energy from the sun. A heat engine, such as a Stirling engine, is carried by the aircraft body for producing power for a propulsion mechanism, such as a propeller. The heat engine has a thermal battery in thermal contact with it so that heat is supplied from the thermal battery. A solar concentrator, such as reflective parabolic trough, is movably connected to an optically transparent section of the aircraft body for receiving and concentrating solar energy from within the aircraft. Concentrated solar energy is collected by a heat collection and transport conduit, and heat transported to the thermal battery. A solar tracker includes a heliostat for determining optimal alignment with the sun, and a drive motor actuating the solar concentrator into optimal alignment with the sun based on a determination by the heliostat.

Solar thermal aircraft

DOEpatents

Bennett, Charles L.

2007-09-18

A solar thermal powered aircraft powered by heat energy from the sun. A heat engine, such as a Stirling engine, is carried by the aircraft body for producing power for a propulsion mechanism, such as a propeller. The heat engine has a thermal battery in thermal contact with it so that heat is supplied from the thermal battery. A solar concentrator, such as reflective parabolic trough, is movably connected to an optically transparent section of the aircraft body for receiving and concentrating solar energy from within the aircraft. Concentrated solar energy is collected by a heat collection and transport conduit, and heat transported to the thermal battery. A solar tracker includes a heliostat for determining optimal alignment with the sun, and a drive motor actuating the solar concentrator into optimal alignment with the sun based on a determination by the heliostat.

The Ordovician Sebree Trough: An oceanic passage to the Midcontinent United States

USGS Publications Warehouse

Kolata, Dennis R.; Huff, W.D.; Bergstrom, Stig M.

2001-01-01

The Sebree Trough is a relatively narrow, shale-filled sedimentary feature extending for several hundred kilometers across the Middle and Late Ordovician carbonate platform of the Midcontinent United States. The dark graptolitic shales within the trough stand in contrast to the coeval bryozoan-brachiopod-echinodermrich limestones on the flanking platforms. We infer from regional stratal patterns, thickness and facies trends, and temporal relations established by biostratigraphy and K-bentonite stratigraphy that the Sebree Trough initially began to develop during late Turinian to early Chatfieldian time (Mohawkian Series) as a linear bathymetric depression situated over the failed late Precambrian-Early Cambrian Reelfoot Rift. Rising sea level and positioning of a subtropical convergence zone along the southern margin of Laurentia caused the rift depression to descend into cool, oxygen-poor, phosphate-rich oceanic waters that entered the southern reaches of the rift from the Iapetus Ocean. The trough apparently formed in a system of epicontinental estuarine circulation marked by a density-stratified water column. Trough formation was accompanied by cessation of carbonate sedimentation, deposition of graptolitic shales, development of hardground omission surfaces, substrate erosion, and local phosphogenesis. The carbonate platforms on either side of the trough are dominated by bryozoan-brachiopod-echinoderm grainstones and packstones that were deposited in zones of mixing where cool, nutrient-rich waters encountered warmer shelf waters. Concurrently, lime mudstone and wackestone were deposited shoreward (northern Illinois, Wisconsin, Iowa, Minnesota, Michigan) in warmer, more tropical shallow seas. Coeval upward growth of the flanking carbonate platforms sustained and enhanced development of the trough shale facies. Five widespread diachronous late Mohawkian and Cincinnatian omission surfaces are present in the carbonate facies of the Midcontinent. These surfaces include sub-Deicke K-bentonite, DSI; top of Black River Limestone, DS2; base and top of the Guttenberg Limestone Member of the Decorah Formation, DS3 and DS4; and top of the Trenton Limestone, DS5. Some of the surfaces correspond to previously described depositional sequence boundaries. All five surfaces, which embody deepening phases on top of high-stand-systems tracts, converge in the Sebree Trough, indicating that the trough was a long-lived feature and was the source of eutrophic waters that episodically spread across the adjacent platforms, terminating carbonate production. Late Turinian and early Chatfieldian incipient drowning episodes were followed by a final drowning event that began in the Sebree Trough during the late Chatfieldian (Climacograptus spiniferus Zone) and reached southernmost Minnesota and other regions far within the platform interior by Richmondian time (Amorphognathus ordovicicus Zone).

Generation of a Parabolic Trough Collector Efficiency Curve from Separate Measurements of Outdoor Optical Efficiency and Indoor Receiver Heat Loss

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kutscher, C.; Burkholder, F.; Stynes, J. K.

2012-02-01

The thermal efficiency of a parabolic trough collector is a function of both the fraction of direct normal radiation absorbed by the receiver (the optical efficiency) and the heat lost to the environment when the receiver is at operating temperature. The thermal efficiency can be determined by testing the collector under actual operating conditions or by separately measuring these two components. This paper describes how outdoor measurement of the optical efficiency is combined with laboratory measurements of receiver heat loss to obtain the thermal efficiency curve. This paper describes this approach and also makes the case that there are advantagesmore » to plotting collector efficiency versus the difference between the operating temperature and the ambient temperature at which the receiver heat loss was measured divided by radiation to a fractional power (on the order of 1/3 but obtained via data regression) - as opposed to the difference between operating and ambient temperatures divided by the radiation. The results are shown to be robust over wide ranges of ambient temperature, sky temperature, and wind speed.« less

Morphological evolution of Jinshan Trough in Hangzhou Bay (China) from 1960 to 2011

NASA Astrophysics Data System (ADS)

Liu, Yifei; Xia, Xiaoming; Chen, Shenliang; Jia, Jianjun; Cai, Tinglu

2017-11-01

An extensive system of tidal channels, starting with Jinshan Trough in the east, is located along the north shore of Hangzhou Bay, China. This contribution investigates the morphological evolution of Jinshan Trough by using 17 bathymetric charts from a series covering a period of 51 years from 1960 to 2011. Three stages of evolution during this period are distinguishable based on the morphology and annual mean volume data. The first stage (1960-1987) is characterized by extension of the trough; the second stage (1987-1996) is a relatively stable period with some adjustments in the trough morphology; the third stage (1996-2011) is marked by the processes of erosion and deposition in the beginning of the period and a subsequent slow erosion process. Spatio-temporal variability of the trough was evaluated by using empirical orthogonal function (EOF) analysis. The first eigenfunction indicates that erosion is the main evolution process and there exists three stages similar to those distinguished from volume variations. The second eigenfunction mainly reflects erosion and deposition in the northwest part of the trough located in the flood tidal current shadow area of the artificial headland in Jinshan. The third eigenfunction mainly reflects annual fluctuations of erosion and deposition in the side slope at the artificial headland in Jinshan. A particularly intense erosion process occurred between 1996 and 1998. The major effects on morphological evolution in Jinshan Trough from 1960 to 2011 were investigated and tentative conclusions were presented. Continuous coastal reclamations in Jinshan had the most pronounced effect on the morphological evolution during the first and the second stages. The storm surge had a pronounced effect on the evolution at the beginning of the third stage.

Magnetic anomaly map of the central Cayman Trough, northwestern Caribbean Sea

USGS Publications Warehouse

Dillon, William P.; Edgar, N. Terence; Parson, Lindsay M.; Scanlon, Kathryn M.; Driscoll, George R.; Jacobs, Colin L.

1993-01-01

This is the first large-scale published map of magnetic anomalies in the central Cayman Trough area. Two previously published very small scale maps based on much less data are a regional map (Gough and Heirtzler, 1969) and a map compiled from several tracklines running parallel to the axis of the Cayman Trough (MacDonald and Holcombe, 1978).

Cut By Troughs

NASA Technical Reports Server (NTRS)

2005-01-01

1 September 2005 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows an impact crater cut by troughs which formed after the crater formed. The crater and troughs have large windblown ripples on their floors. The ripples, troughs, craters, and other surfaces in this scene have all been mantled by dust. Dark streaks on slopes indicate areas where avalanches of dry dust have occurred. These features are located on Sacra Mena, a large mesa in the Kasei Valles region.

Location near: 25.4oN, 66.8oW Image width: width: 3 km (1.9 mi) Illumination from: lower left Season: Northern Autumn

Aeolian Sediment Transport Pathways and Aerodynamics at Troughs on Mars

NASA Technical Reports Server (NTRS)

Bourke, Mary C.; Bullard, Joanna E.; Barnouin-Jha, Olivier S.

2004-01-01

Interaction between wind regimes and topography can give rise to complex suites of aeolian landforms. This paper considers aeolian sediment associated wit11 troughs on Mars and identifies a wider range of deposit types than has previously been documented. These include wind streaks, falling dunes, "lateral" dunes, barchan dunes, linear dunes, transverse ridges, sand ramps, climbing dunes, sand streamers, and sand patches. The sediment incorporated into these deposits is supplied by wind streaks and ambient Planitia sources as well as originating within the trough itself, notably from the trough walls and floor. There is also transmission of sediment between dneTsh. e flow dynamics which account for the distribution of aeolian sediment have been modeled using two-dimensional computational fluid dynamics. The model predicts flow separation on the upwind side of the trough followed by reattachment and acceleration at the downwind margin. The inferred patterns of sediment transport compare well with the distribution of aeolian forms. Model data indicate an increase of wind velocity by approx. 30 % at the downwind trough margin. This suggests that the threshold wind speed necessary for sand mobilization on Mars will be more freqentmlye t in these inclined locations.

Studies of plasma irregularities and convection in the polar ionosphere using HILAT, SABRE and EISCAT. Interim report, 1 Feb 88-31 Mar 89

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, T.B.; Lester, M.; Wilkinson, A.J.

A statistical study of the F-region main ionospheric trough has been undertaken with EISCAT common programme data to assess the possibility that the trough region is a perferential region for the generation of E-region irregularities. Three years of CP-3 data from EISCAT formed the basis of this study. Backscatter observed by the coherent radar, SABRE, was also utilized to study the occurrence of irregularities in the E-region. On 26 out of the 36 days when the trough was observed by EISCAT, SABRE observed coherent backscatter. Although this percentage seems high, there was no consistent relationship between the latitude of themore » trough minimum and the latitude of peak backscatter intensity. A case study involving a four day run of EISCAT in September 1986 indicates that the trough latitude can be affected by changes in the interplanetary magnetic field north-south components. On two days rapid decreases in the latitude of the trough were related to a southward turning of the IMF and the onset of backscatter. The high percentage of occurrence of backscatter is believed to be caused by enhanced convection.« less

Crustal and upper mantle velocity structure of the Salton Trough, southeast California

USGS Publications Warehouse

Parsons, T.; McCarthy, J.

1996-01-01

This paper presents data and modelling results from a crustal and upper mantle wide-angle seismic transect across the Salton Trough region in southeast California. The Salton Trough is a unique part of the Basin and Range province where mid-ocean ridge/transform spreading in the Gulf of California has evolved northward into the continent. In 1992, the U.S. Geological Survey (USGS) conducted the final leg of the Pacific to Arizona Crustal Experiment (PACE). Two perpendicular models of the crust and upper mantle were fit to wide-angle reflection and refraction travel times, seismic amplitudes, and Bouguer gravity anomalies. The first profile crossed the Salton Trough from the southwest to the northeast, and the second was a strike line that paralleled the Salton Sea along its western edge. We found thin crust (???21-22 km thick) beneath the axis of the Salton Trough (Imperial Valley) and locally thicker crust (???27 km) beneath the Chocolate Mountains to the northeast. We modelled a slight thinning of the crust further to the northeast beneath the Colorado River (???24 km) and subsequent thickening beneath the metamorphic core complex belt northeast of the Colorado River. There is a deep, apparently young basin (???5-6 km unmetamorphosed sediments) beneath the Imperial Valley and a shallower (???2-3 km) basin beneath the Colorado River. A regional 6.9-km/s layer (between ???15-km depth and the Moho) underlies the Salton Trough as well as the Chocolate Mountains where it pinches out at the Moho. This lower crustal layer is spatially associated with a low-velocity (7.6-7.7 km/s) upper mantle. We found that our crustal model is locally compatible with the previously suggested notion that the crust of the Salton Trough has formed almost entirely from magmatism in the lower crust and sedimentation in the upper crust. However, we observe an apparently magmatically emplaced lower crust to the northeast, outside of the Salton Trough, and propose that this layer in part predates Salton Trough rifting. It may also in part result from migration of magmatic spreading centers associated with the southern San Andreas fault system. These spreading centers may have existed east of their current locations in the past and may have influenced the lower crust and upper mantle to the east of the current Salton Trough.

Fast flow of Jakobshavn Isbræ and its subglacial drainage system

NASA Astrophysics Data System (ADS)

Werder, M. A.; Joughin, I. R.

2013-12-01

Jakobshavn Isbræ and many other outlet glaciers of present and past ice sheets lie in deep troughs which often have several overdeepened sections. The subglacial drainage system of such glaciers is heavily influenced by two effects caused by the pressure dependence of the melting point of water. The melting point decreases with increasing water pressure, this enhances wall-melt in downward sloping channels and diminishes wall-melt in upward sloping channels. Thus the first effect is the well known shutdown of channels on steep adverse bed slopes of overdeepenings and the associated high water pressure/low effective pressure. The second effect is a 2D effect and has not received much/any attention so far: the orientation of a channel will be deflected from the direction of the (negative) hydraulic potential gradient (which drives the water flow) towards the steepest slope of the bed. This leads to the enhanced formation of side channels dipping into the trough at about a 45° angle. This efficient connection between the margin and the trough equalizes the hydraulic potential, again leading to higher water pressure in the trough. We investigate these two effects with the 2D subglacial drainage system model GlaDS using Jakobshavn Isbræ as an example. We compare model runs with the pressure melt term disabled and enabled. With the term disabled the main channel situated in the trough is continuous and produces a large depression in the hydraulic potential and consequently high effective pressure in the trough (1-2MPa). Conversely, with the term enabled the main channel becomes discontinuous on steep adverse bed slopes and many side channels form on the margins of the trough. This leads to a hydraulic potential in the trough which is higher than in the surrounding area and consequently the effective pressure is low (0-1MPa). Low effective pressure leads to reduced basal drag and thus to more basal sliding. The modeled large decrease of effective pressure in the trough due to the pressure dependence of the melting point of water suggests that basal drag will be small and that sliding speeds are large. Thus, this may be one of the leading causes for the fast flow of Jakobshavn Isbræ and other glaciers in deep troughs.

Simultaneous Sea-Level Oscillations in Japanese Bays Induced by the Tsunami of Nankai-Trough Earthquake

NASA Astrophysics Data System (ADS)

Oishi, Y.; Furumura, T.; Imamura, F.; Yamashita, K.; Sugawara, D.

2016-12-01

In this study, we investigate the response of bays to the tsunami of Nankai-trough earthquake based on tsunami simulations and demonstrate the possibility that sea-level oscillation of each bay, which is induced by an incident tsunami, interacts with those of other bays. Several major cities in Japan, including the capital, are located in the bays near the Nankai trough and it is assumed that these cities will be largely affected by the tsunamis caused by recurring large earthquakes at the trough. Therefore, it is very important for these populated cities to understand the mechanism and properties of the tsunami-induced oscillations that continue for a long time in bays to draw up evacuation plans. To investigate the response of bays for various tsunamis that may occur in the Nankai trough area, we distributed the tsunami sources that have the form of a 2-D Gaussian function around the Nankai trough. From simulations with these sources, it was found that strong oscillations of bay water occur when the source is located in the bay itself or when strong oscillations occur in other bays. For example, when the Tosa bay oscillates, the Tokyo bay that is 600 km away from the Tosa bay also oscillates. Among the bays around the Nankai trough, the Suruga bay, the deepest bay in Japan with a 2500-km depth, oscillates more strongly than other bays for most cases. To check the influence of the strong oscillations in the Suruga bay on other bays, we conducted tsunami simulations using a modified topography model in which the Suruga bay is artificially landfilled. As a consequence, the strength of oscillations in the adjacent bays are reduced by 20-30%, suggesting the large influence of the distinguished oscillation of the Suruga bay on these bays. We finally conducted tsunami simulations using the eleven Nankai-trough earthquake scenarios of the Central Disaster Prevention Council (CDPC) of Japan as tsunami sources, and the mutual relation regarding the strengths of oscillations among the bays around the Nankai trough was confirmed irrespective of the earthquake scenarios. The results of this study suggest that oscillations of the bays do not occur independently in each bay but simultaneously occur among the bays. More detailed characteristics of the response of the bays to the tsunamis in the Nankai-trough area will be discussed in the presentation.

Controls of bioclastic turbidite deposition in eastern Muertos Trough northeast Caribbean Sea

DOE Office of Scientific and Technical Information (OSTI.GOV)

Forsthoff, G.M.; Holcombe, T.L.

1985-02-01

A study of seismic-reflection profiles and sediment cores establishes regional bathymetric and source area control over the composition, transport, and distribution of turbidites in the eastern Muertos Trough, Bioclastic (carbonate) turbidites dominate the eastern portion of the trough. Analyses of carbon content and sand-sized components suggest that the bioclastic turbidites (characterized by planktonic foraminifera, pteropods, and sponge spicules) are reworked pelagic oozes originally deposited on the outer-shelf and upper-slope areas south of St. Croix and eastern Puerto Rico. The presence of several intrashelf and upper-slope basins prohibits shallow-water carbonate sediments from entering the Muertos Trough. Volcanic rock fragments derived frommore » Puerto Rico are transported to the trough via the Guayanilla Canyon system. Mixing of the volcanic fragments with outer-shelf and upper-slope lutites results in mixed bioclastic-terrigenous turbidites south of central and western Puerto Rico. The paucity of shallow-water carbonate sediments in the trough suggests that the submarine canyons are effective conduits for the rapid transport of volcaniclastic sands across the shelf and thereby prevent extensive mixing with inner- and middle-shelf carbonate sediments. Sediment transport within the trough is primarily axial in an east-west direction. Outer trench-wall fault scarps, south of Guayanilla Canyon, limit the southerly progradation of the trench-wedge facies and deflect incoming gravity flows in a down-axis (westward) direction. Where no faults exist, the trench wedge progrades southward and interfingers with the pelagic sediments of the northern Venezuelan basin.« less

Weak lensing by galaxy troughs in DES Science Verification data

DOE PAGES

Gruen, D.; Friedrich, O.; Amara, A.; ...

2015-11-29

In this study, we measure the weak lensing shear around galaxy troughs, i.e. the radial alignment of background galaxies relative to underdensities in projections of the foreground galaxy field over a wide range of redshift in Science Verification data from the Dark Energy Survey. Our detection of the shear signal is highly significant (10σ–15σ for the smallest angular scales) for troughs with the redshift range z ϵ [0.2, 0.5] of the projected galaxy field and angular diameters of 10 arcmin…1°. These measurements probe the connection between the galaxy, matter density, and convergence fields. By assuming galaxies are biased tracers ofmore » the matter density with Poissonian noise, we find agreement of our measurements with predictions in a fiducial Λ cold dark matter model. The prediction for the lensing signal on large trough scales is virtually independent of the details of the underlying model for the connection of galaxies and matter. Our comparison of the shear around troughs with that around cylinders with large galaxy counts is consistent with a symmetry between galaxy and matter over- and underdensities. In addition, we measure the two-point angular correlation of troughs with galaxies which, in contrast to the lensing signal, is sensitive to galaxy bias on all scales. The lensing signal of troughs and their clustering with galaxies is therefore a promising probe of the statistical properties of matter underdensities and their connection to the galaxy field.« less

The Nova-Canton Trough and the Late Cretaceous evolution of the central Pacific

NASA Astrophysics Data System (ADS)

Joseph, Devorah; Taylor, Brain; Shor, Alexander N.; Yamazaki, Toshitsugu

Free-air gravity anomalies derived from satellite altimetry data show that the major Pacific fracture zones, from the Pau to Marquesas, are co-polar about an Euler pole located at 150.5°W, 34.6°S for the period preceding chron 33 and including a large portion of the Cretaceous Normal Superchron. They also show continuity of the Clipperton Fracture Zone through the Line Islands to the Nova-Canton ridge and trough; this Canton-Clipperton trend is co-polar to the same pole. Sidescan-sonar and bathymetry data in the Nova-Canton Trough region reveal N140°E-striking abyssal hill topography south of the N70°E-striking structures of the Nova-Canton Trough and crustal fabric striking normal to the trough (N160°E) to the north. We conclude that the Nova-Canton Trough is the Middle Cretaceous extension of the Clipperton Fracture Zone. We propose that the anomalous depths (7000-8400 m) of the trough between 167°30'-168°30'W are the result of a complex plate reorganization. Conjugate magnetic anomaly lineations M1-M3 in the Phoenix lineations between the Central Pacific Fracture Zone and the Phoenix Fracture Zone and the absence of lineations younger than anomaly M3 west of the Phoenix Fracture Zone suggest that spreading may have gradually ceased along the Pacific-Phoenix system from west to east. We infer that the remaining active segment of the Pacific-Phoenix spreading system after anomaly M1 time was the easternmost section of the Phoenix lineations. At ˜M0 time, the Pacific-Phoenix spreading axis stretched from lineated bathymetric depressions lying between 180°W and the Phoenix Islands to ˜168°W and included the western deep of the Nova-Canton Trough. We hypothesize that accretion terminated on the Pacific-Phoenix spreading axis shortly after M0 time and that the absence of an M0 isochron in the region between the eastern Phoenix lineations and the Nova-Canton Trough, or along the Nova-Canton Trough itself, may be due to a decrease in spreading rate prior to termination. We concur with previous hypotheses that portions of the Phoenix plate were trapped on the Pacific plate by a ridge jump south to the nascent Manihiki Plateau; some portions were overprinted by the Aptian volcanism that formed the Manihiki Plateau and Robbie Ridge. Pacific-Farallon spreading south of the Nova-Canton Trough jumped westwards, initiating transcurrent motion along the easternmost section of the failed ˜M0 spreading axis (the western deep of the Nova-Canton Trough) which subsequently became the western end of the Clipperton (Pacific-Farallon) transform. In our reconstruction, the northeast and southeast margins of the Manihiki Plateau are rifted margins that form the western limit of Pacific-Farallon spreading between the Clipperton, Galapagos, and Marquesas fracture zones.

Comprehensive analysis of earthquake source spectra and swarms in the Salton Trough, California

NASA Astrophysics Data System (ADS)

Chen, X.; Shearer, P. M.

2011-09-01

We study earthquakes within California's Salton Trough from 1981 to 2009 from a precisely relocated catalog. We process the seismic waveforms to isolate source spectra, station spectra and travel-time dependent spectra. The results suggest an average P wave Q of 340, agreeing with previous results indicating relatively high attenuation in the Salton Trough. Stress drops estimated from the source spectra using an empirical Green's function (EGF) method reveal large scatter among individual events but a low median stress drop of 0.56 MPa for the region. The distribution of stress drop after applying a spatial-median filter indicates lower stress drops near geothermal sites. We explore the relationships between seismicity, stress drops and geothermal injection activities. Seismicity within the Salton Trough shows strong spatial clustering, with 20 distinct earthquake swarms with at least 50 events. They can be separated into early-Mmax and late-Mmax groups based on the normalized occurrence time of their largest event. These swarms generally have a low skew value of moment release history, ranging from -9 to 3.0. The major temporal difference between the two groups is the excess of seismicity and an inverse power law increase of seismicity before the largest event for the late-Mmax group. All swarms exhibit spatial migration of seismicity at a statistical significance greater than 85%. A weighted L1-norm inversion of linear migration parameters yields migration velocities from 0.008 to 0.8 km/hour. To explore the influence of fluid injection in geothermal sites, we also model the migration behavior with the diffusion equation, and obtain a hydraulic diffusion coefficient of approximately 0.25 m2/s for the Salton Sea geothermal site, which is within the range of expected values for a typical geothermal reservoir. The swarms with migration velocities over 0.1 km/hour cannot be explained by the diffusion curve, rather, their velocity is consistent with the propagation velocity of creep and slow slip events. These variations in migration behavior allow us to distinguish among different driving processes.

Ocular Penetration and Anti-inflammatory Activity of Ketorolac 0.45% and Bromfenac 0.09% Against Lipopolysaccharide-Induced Inflammation

PubMed Central

Galindo, Danielle; Villanueva, Linda; Nguyen, Cathy; Patel, Milan; Borbridge, Lisa; Attar, Mayssa; Schiffman, Rhett M.; Hollander, David A.

2011-01-01

Abstract Purpose Anti-inflammatory activity of topical nonsteroidal anti-inflammatory drugs is mediated by suppression of cyclooxygenase (COX) isoenzymes. This study compared ocular penetration and inflammation suppression of topical ketorolac 0.45% and bromfenac 0.09% ophthalmic solutions in a rabbit model. Methods At hour 0, 36 rabbits received ketorolac 0.45%, bromfenac 0.09%, or an artificial tear 3 times once every 20 min. Half of the rabbits in each group then received intravenous injections of lipopolysaccharide (LPS) and fluorescein isothiocyanate (FITC)–dextran at hour 1, and the other half at hour 10. Aqueous and iris-ciliary body (ICB) samples were collected in the former group at hour 2 (peak) and in the latter group at hour 11 (trough) An additional group of 6 animals received only FITC-dextran, and samples were collected 1 h later. Peak and trough nonsteroidal anti-inflammatory drug concentrations were compared with previously determined half-maximal inhibitory concentrations (IC50) for COX isoenzymes. Results Peak and trough aqueous and ICB concentrations of ketorolac were at least 7-fold or greater than those of bromfenac. At peak levels, both ketorolac 0.45% and bromfenac 0.09% significantly inhibited LPS-induced aqueous prostaglandin E2 and FITC-dextran elevation (P < 0.01). At trough, both study drugs significantly inhibited LPS-induced aqueous prostaglandin E2 elevation (P < 0.05), but only ketorolac 0.45% significantly reduced LPS-induced aqueous FITC-dextran elevation (P < 0.01). Aqueous and ICB ketorolac concentrations exceeded its IC50 for COX-1 and COX-2 at peak and trough. Aqueous and ICB bromfenac levels exceeded its IC50 for COX-2 at peak and trough, but not for COX-1 at trough aqueous levels and peak and trough ICB levels. Conclusions Both ketorolac 0.45% and bromfenac 0.09% effectively suppressed inflammation at peak. At trough, only ketorolac 0.45% effectively suppressed inflammation as measured by FITC-dextran leakage. The difference in inflammation suppression may be due to differences in tissue concentrations and/or greater COX-1 suppression by ketorolac 0.45%. PMID:21351868

Multiple-dose pharmacokinetics of daptomycin during continuous venovenous haemodiafiltration.

PubMed

Wenisch, Judith M; Meyer, Brigitte; Fuhrmann, Valentin; Saria, Katrin; Zuba, Clara; Dittrich, Peter; Thalhammer, Florian

2012-04-01

Daptomycin is bactericidal against Gram-positive bacteria, with peak-dependent effect but trough-dependent toxicity. This study was performed to develop dosing recommendations in continuous venovenous haemodiafiltration (CVVHDF). Nine critically ill patients in intensive care units of the Medical University Hospital of Vienna, requiring CVVHDF due to acute renal failure and antimicrobial treatment, were included. Blood and effluent samples were collected over 72 h to determine daptomycin concentrations by HPLC. Pharmacokinetic parameters were based on 10 sampling timepoints during the first 24 h, and peak and trough samples thereafter. An open two-compartment model was fitted to each subject's plasma concentration-time data. Simulations of serum concentration-time profiles after different doses and intervals were performed using ADAPT 5. Peak plasma concentrations with 6 mg/kg daptomycin were 62.2 ± 16.2, 66.1 ± 17.3 and 78.5 ± 22.1 mg/L on days 1, 2 and 3, respectively. The total clearance was 6.1 ± 4.9 mL/min, and the elimination half-life was 17.8 ± 9.7 h. Daptomycin was filtrated and could therefore be measured in the effluent. Protein binding was lower than that seen in healthy volunteers. The unbound fraction was 16 ± 4.5%. All subjects maintained trough serum concentrations above 4 mg/L, at which relevant pathogens are considered daptomycin-susceptible. Accumulation resulted when daptomycin was given every 24 h. Simulation of 8 mg/kg daptomycin given every 48 h resulted in adequate levels without accumulation. We recommend 8 mg/kg daptomycin every 48 h in patients on CVVHDF and therapeutic drug monitoring, if possible.

Performance of coagulation tests in patients on therapeutic doses of rivaroxaban. A cross-sectional pharmacodynamic study based on peak and trough plasma levels.

PubMed

Francart, Suzanne J; Hawes, Emily M; Deal, Allison M; Adcock, Dorothy M; Gosselin, Robert; Jeanneret, Cheryl; Friedman, Kenneth D; Moll, Stephan

2014-06-01

Knowledge of anticoagulation status during rivaroxaban therapy is desirable in certain clinical situations. It was the study objective to determine coagulation tests most useful for assessing rivaroxaban's anticoagulant effect. Peak and trough blood samples from 29 patients taking rivaroxaban 20 mg daily were collected. Mass spectrometry and various coagulation assays were performed. "On-therapy range" was defined as the rivaroxaban concentrations determined by LC-MS/MS. A "misprediction percentage" was calculated based on how often results of each coagulation assay were in the normal reference range, while the rivaroxaban concentration was in the "on-therapy" range. The on-therapy range was 8.9-660 ng/ml. The misprediction percentages for prothrombin time (PT) and activated partial thromboplastin time (aPTT), using multiple reagents and coagulometers, ranged from 10%-52% and 31%-59%, respectively. PT, aPTT and activated clotting time (ACT) were insensitive to trough rivaroxaban: 59%, 62%, and 80% of samples had a normal result, respectively. Over 95% of PT and ACT values were elevated at peak. Four different rivaroxaban calibrated anti-Xa assays had R² values >0.98, demonstrating strong correlations with rivaroxaban drug levels. In conclusion, PT, aPTT and ACT are often normal in patients on therapeutic doses of rivaroxaban. However, PT and ACT may have clinical utility at higher drug plasma levels. Rivaroxaban calibrated anti-factor Xa assays can accurately identify low and high on-therapy rivaroxaban drug levels and, therefore, have superior utility in all clinical situations where assessment of anticoagulation status may be beneficial.

Is Blood Eosinophil Count a Predictor of Response to Bronchodilators in Chronic Obstructive Pulmonary Disease? Results from Post Hoc Subgroup Analyses.

PubMed

Iqbal, Ahmar; Barnes, Neil C; Brooks, Jean

2015-10-01

Chronic obstructive pulmonary disease (COPD) patients with blood eosinophil (EOS) count ≥ 2% benefit from exacerbation reductions with inhaled corticosteroids (ICSs). We conducted post hoc analyses to determine if EOS count ≥ 2% is a marker for greater responsiveness to the bronchodilators umeclidinium (UMEC; long-acting muscarinic antagonist), vilanterol (VI; long-acting β2-agonist) or UMEC/VI combination. Effects of once-daily UMEC/VI 62.5/25, UMEC 62.5 and VI 25 µg versus placebo on trough forced expiratory volume in one second (FEV1), Transition Dyspnoea Index (TDI), St George's Respiratory Questionnaire (SGRQ) scores and adverse event (AE) incidences in four completed, 6-month studies were assessed by EOS subgroup. Trough FEV1 was also evaluated by ICS use and EOS subgroup. Analyses were performed using a repeated measures model. At baseline, 2437 of 4647 (52%) patients had EOS count ≥ 2%. Overall, ≈ 50% of patients used ICSs. At day 169, no notable variations were observed in trough FEV1 least squares mean differences between EOS subgroups versus placebo for UMEC/VI, UMEC and VI; results according to ICS use were similar. No differences were reported between EOS subgroups in TDI and SGRQ scores on day 168, or for incidences of AEs, serious AEs and AEs leading to withdrawal. Response to UMEC/VI, UMEC and VI in terms of trough FEV1, dyspnoea and health-related quality of life was similar for COPD patients with baseline EOS counts ≥ 2 or <2%. EOS count did not appear to predict bronchodilator response in either ICS users or non-users.

Facies mosaic in a fiord: Carboniferous-Permian Talchir Formation, India

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bose, P.K.; Mukhopadhyay, G.; Bhattacharya, H.N.

1988-01-01

Facies analysis of the basal 37m of the Carboniferous-Permian Talchir Formation is a glacier-fed bedrock trough in Dudhi nala, Bihar, India, provides insight into the pattern of sedimentation of course gravels in a fiord. Rapid transitions between 11 recognized facies, together with their complex organization, random variability in bed thickness, and differences in clast, shape, size, and composition indicate coalescence of fans developed from numerous point sources bordering the elongated trough. Converging slide masses and lodgment tillites on the slopes flanking the trough give way to sediment gravity flow deposits composed of an array of conglomerates (matrix and clast supportedmore » with normal, inverse of absence of grading), attendant turbidite sands, and prodelta mud. The rheology of the in-trough flows ranged from plastic laminar to fluidal turbulent in response to flow from slope to floor of the trough. Rapid calving of icebergs during the onset of deglaciation established a wave regime at the mouth of the trough and deposited cross-stratified sandstone replete with dripstones. The impact of large dripstones landing triggered turbidity currents. Continued rise in water level led to eventual preservation of the fan complex under onlapping wave-built shoal facies that grade into a sequence of upward-thinning hummocky cross-stratified sandstone beds virtually devoid of dripstones.« less

Altitude Variation of the Plasmapause Signature in the Main Ionospheric Trough

NASA Technical Reports Server (NTRS)

Grebowsky, Joseph M.; Benson, Robert F.; Webb, Phillip A.; Truhlik, Vladimir; Bilitza, Dieter

2009-01-01

The projection of the plasmapause magnetic-field lines to low altitudes, where the light-ion chemistry is dominated by O(+), tends to occur near the minimum electron density in the main (midlatitude) electron density trough at night. With increasing attitude in the trough, where H(+) emerges as the dominant iota on the low-latitude boundary, we have found cases where the plasmapause field lines are located on the sharp low-Latitude side of the trough as expected if this topside ionosphere H(+) distribution varies in step with the plasmapause gradient in the distant plasmasphere. These conclusions are based on near-equatorial crossings of the plasmapause (corresponding to the steep gradient in the dominant species H(+) by the Explorer-45 satellite as determined from electric-field measurements by Maynard and Cauffman in the early 1970s and ISIS-2 ionospheric topside-sounder measurements. The former data have now been converted to digital form and made available at http://nssdcftp.gsfc.nasa.gov. The latter provide samples of nearly coincident observations of ionospheric main trough crossings near the same magnetic-field lines of the Explorer 45-determined equatorial plasmapause. The ISIS-2 vertical electron density profiles are used to infer where the F-region transitions from an O(+) to a H(+) dominated plasma through the main trough boundaries.

Concentrating Solar Power

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weinstein, Lee A.; Loomis, James; Bhatia, Bikram

2015-12-09

Solar energy is a bountiful renewable energy resource: the energy in the sunlight that reaches Earth in an hour exceeds the energy consumed by all of humanity in a year.(1) While the phrase “solar energy conversion” probably brings photovoltaic (PV) cells to mind first, PV is not the only option for generating electricity from sunlight. Another promising technology for solar energy conversion is solar–thermal conversion, commonly referred to as concentrating solar power (CSP).(2) The first utility-scale CSP plants were constructed in the 1980s, but in the two decades that followed, CSP saw little expansion.(3, 4) More recent years, however, havemore » seen a CSP renaissance due to unprecedented growth in the adoption of CSP.(3, 5) Photographs of two operating CSP plants, a parabolic trough collector plant and a central receiver (or “power tower”), are shown here.« less

Climatology of the winter Red Sea Trough

NASA Astrophysics Data System (ADS)

Awad, Adel M.; Almazroui, Mansour

2016-12-01

In this study, a new and objective method for detecting the Red Sea Trough (RST) was developed using mean sea level pressure (SLP) data from NCEP/NCAR reanalysis dataset from the winters of 1956 to 2015 to identify the Sudan Low and its trough. Approximately 96% of the winter RSTs were generated near two main sources, South Sudan and southeastern Sudan, and approximately 85% of these troughs were in four of the most outer areas surrounding the northern Red Sea. Moreover, from west to east of the Red Sea, the RST was affected by the relationships between the Siberian High and Azores High. The RST was oriented to the west when the strength of the Siberian High increased and to the east when the strength of the Azores High increased. Furthermore, the synoptic features of the upper level of the RST emphasize the impacts of subtropical anticyclones at 850 hPa on the orientation of the RST, the impacts of the northern cyclone trough and the maximum wind at a pressure level of 250 hPa. The average static stability between 1000 hPa and 500 hPa demonstrated that the RST followed the northern areas of low static stability. The results from previous studies were confirmed by a detailed case study of the RST that extended to its central outermost area. The results of a detailed case study of the short RST indicated that the trough becomes shorter with increasing static stability and that the Azores and Siberian high-pressure systems influence the northern region of the trough while the maximum upper wind shifts south of the climate position.

Petroleum prospects of Benue trough, Nigeria

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nawachukwu, J.I.

1985-04-01

Exploration activities in the Benue trough have been minimal over the years, mainly because of large petroleum deposits found in the adjoining Niger delta and early gas finds in the Anambra basin, south of the Benue trough. The recent increase in exploration activities in the trough has necessitated a reevaluation of the petroleum potentials of the basin. In this study, the time-temperature index (TTI) method was used to evaluate petroleum prospects of the basin. An increase in geothermal gradient resulted in a decrease in depth to the oil window, with the sediments maturing earlier at higher geothermal gradients. At geothermalmore » gradients of 1.5-1.9/sup 0/F/100 ft (2.73.5/sup 0/C/100 m) and maximum TTI values, the Asu River Group and the Eze-Aku Group of sediments are still within the gas-generating stage. The Awgu Shale and the Nkporo Shale are capable of generating gas at geothermal gradients of 2.3-2.7/sup 0/F/100 ft (4.2-4.9/sup 0/C/100 m). The Benue trough is essentially a gas-condensate basin with little oil. Exploration targets in the basin include both the sub-Santonian and superSantonian sediments, with the Eze-Aku Group, Awgu Shale, and Nkporo Shale being more prospective than the stratigraphically lower Asu River Group. In general, the middle Benue trough is considered to be the most prospective area within the trough because depths to the mature zones are moderate (6,600-13,000 ft; 2-4 km). These depths are variable, decreasing northeastward and increasing southwestward toward the Niger delta.« less

Katabatic jumps in the Martian northern polar regions

NASA Astrophysics Data System (ADS)

Spiga, Aymeric; Smith, Isaac

2018-07-01

Martian polar regions host active regional wind circulations, such as the downslope katabatic winds which develop owing to near-surface radiative cooling and sloped topography. Many observations (stratigraphy from radar profiling, frost streaks, spectral analysis of ices) concur to show that aeolian processes play a key role in glacial processes in Martian polar regions. A spectacular manifestation of this resides in elongated clouds that forms within the polar spiral troughs, a series of geological depressions in Mars' polar caps. Here we report mesoscale atmospheric modeling in Martian polar regions making use of five nested domains operating a model downscaling from horizontal resolutions of twenty kilometers to 200 m in a typical polar trough. We show that strong katabatic jumps form at the bottom of polar troughs with an horizontal morphology and location similar to trough clouds, large vertical velocity (up to +3 m/s) and temperature perturbations (up to 20 K) propitious to cloud formation. This strongly suggests that trough clouds on Mars are caused by katabatic jumps forming within polar troughs. This phenomena is analogous to the terrestrial Loewe phenomena over Antarctica's slopes and coastlines, resulting in a distinctive "wall of snow" during katabatic events. Our mesoscale modeling results thereby suggest that trough clouds might be present manifestations of the ice migration processes that yielded the internal cap structure discovered by radar observations, as part of a "cyclic step" process. This has important implications for the stability and possible migration over geological timescales of water ice surface reservoirs-and, overall, for the evolution of Mars' polar caps over geological timescales.

Laboratory measurement of apixaban using anti-factor Xa assays in acute ischemic stroke patients with non-valvular atrial fibrillation.

PubMed

Shin, Hyoshim; Cho, Min-Chul; Kim, Rock Bum; Kim, Chang-Hun; Choi, Nack-Cheon; Kim, Soo-Kyung; Koh, Eun-Ha

2018-02-01

Apixaban is effective and safe for preventing stroke, and its usage has increased exponentially in recent years. However, data concerning the therapeutic range of apixaban is limited. This study determined the trough and peak levels of apixaban-specific anti-factor Xa activity (AFXaA) in acute ischemic stroke patients with non-valvular atrial fibrillation (NVAF) in Korea. The study included 85 patients who received apixaban. Blood samples were taken to measure the trough and peak levels of AFXaA using a chromogenic anti-factor assay, as well as prothrombin time (PT) and activated partial thromboplastin time (aPTT). We also reviewed complications such as major bleeding of patients treated with apixaban. In patients given a 5.0-mg apixaban dose, the median trough and peak levels of AFXaA were 104.5 and 202.0 ng/mL. In patients given a 2.5-mg apixaban dose, the median trough and peak AFXaA levels were 76.0 and 151.0 ng/mL. The PT showed a positive correlation with increased AFXaA activity at both levels (Trough R = 0.486, Peak R = 0.592), but the aPTT had no relationship with AFXaA activity at both levels (Trough R = 0.181, Peak R = 0.129). Two cases with intracranial bleeding belonged to the highest AFXaA quartile (Trough, p = 0.176; Peak, p = 0.053). In conclusion, we determined the trough and peak levels of AFXaA in patients with NVAF while being treated with the apixaban in Korea. Our results could be used as a starting point when setting the reference ranges for laboratories using anti-Xa assay. Large-scale studies are needed to establish the reference range for AFXaA in patients with NVAF.

Early vedolizumab trough levels predict mucosal healing in inflammatory bowel disease: a multicentre prospective observational study.

PubMed

Yacoub, W; Williet, N; Pouillon, L; Di-Bernado, T; De Carvalho Bittencourt, M; Nancey, S; Lopez, A; Paul, S; Zallot, C; Roblin, X; Peyrin-Biroulet, L

2018-04-01

The correlation between vedolizumab trough levels during induction therapy and mucosal healing remains unknown. To compare early vedolizumab trough levels in patients with and without mucosal healing within the first year after treatment initiation. We prospectively collected vedolizumab trough levels in all inflammatory bowel disease patients at weeks 2, 6 and 14 of vedolizumab treatment in three French referral centres between 1 June 2014 and 31 March 2017. Results of every patient that underwent mucosal assessment by magnetic resonance imaging and/or endoscopy in the first year after treatment initiation were analysed. Median vedolizumab trough levels in the overall population (n = 82) were 27 μg/mL (interquartile range, IQR 21.2-33.8 μg/mL) at week 2, 23 μg/mL (IQR 15-34.5 μg/mL) at week 6 and 10.7 μg/mL (IQR 4.6-20.4 μg/mL) at week 14. Only median vedolizumab trough levels at week 6 differed between patients with and without mucosal healing within the first year after treatment initiation (26.8 vs 15.1 μg/mL, P = 0.035). A cut-off trough level of 18 μg/mL at week 6 predicted mucosal healing within the first year after the start of vedolizumab with an area under the receiver operating curve of 0.735 (95% confidence interval 0.531-0.939). A vedolizumab trough level above 18 μg/mL at week 6 was the only independent variable associated with mucosal healing within the first year of treatment (odds ratio 15.7, 95% confidence interval 2.4-173.0, P = 0.01). Early therapeutic drug monitoring might improve timely detection of vedolizumab-treated patients in need for an intensified dosing regimen. © 2018 John Wiley & Sons Ltd.

Correlation between production performance and feeding behavior of steers on pasture during the rainy-dry transition period.

PubMed

Brandão, Rita K C; de Carvalho, Gleidson G P; Silva, Robério R; Dias, Daniel L S; Mendes, Fabrício B L; Lins, Túlio O J D'A; Pereira, Maria M S; Guimarães, Joanderson O; Tosto, Manuela S L; Rufino, Luana M de A; de Araujo, Maria L G M L

2018-01-01

The aim of this study was to evaluate the correlation between production performance and feeding behavior of steers reared on pasture during the rainy-dry transition period. Twenty-two ½ Holstein-Zebu crossbred steers at an average age of 10 months and with an average initial body weight of 234.5 ± 16.0 kg were distributed in a completely randomized design with two types of supplementation and eleven replications. Pearson's linear correlation analysis was performed between behavioral variables and weight gain and feed conversion. Correlation coefficients were tested by the t test. The time expended feeding at the trough was positively correlated (P < 0.05) with average daily gain (ADG) and with the number of periods of permanence at the trough. Bite rate and the number of bites per day were positively correlated (P < 0.05) with ADG and negatively (P < 0.05) with feed conversion, unlike the number of bites per swallow, which was negatively correlated (P < 0.05) with ADG. There was a positive correlation (P < 0.05) between feed efficiency in dry matter and neutral detergent fiber and ADG. Feeding behavior characteristics have little association with the production performance of cattle on pasture receiving mineral or energy-protein supplementation.

Evidence and mechanism of Hurricane Fran-Induced ocean cooling in the Charleston Trough

NASA Astrophysics Data System (ADS)

Xie, Lian; Pietrafesa, L. J.; Bohm, E.; Zhang, C.; Li, X.

Evidence of enhanced sea surface cooling during and following the passage of Hurricane Fran in September 1996 over an oceanic depression located on the ocean margin offshore of Charleston, South Carolina (referred to as the Charleston Trough), [Pietrafesa, 1983] is documented. Approximately 4C° of sea surface temperature (SST) reduction within the Charleston Trough following the passage of Hurricane Fran was estimated based on SST imagery from Advanced Very High Resolution Radiometer (AVHRR) on the NOAA-14 polar orbiting satellite. Simulations using a three-dimensional coastal ocean model indicate that the largest SST reduction occurred within the Charleston Trough. This SST reduction can be explained by oceanic mixing due to storm-induced internal inertia-gravity waves.

Research of the Effect Caused by Terrestrial Power Sources on the Near-Earth Space above China based on DEMETER Satellite Data

NASA Astrophysics Data System (ADS)

Zhang, C.; Wu, J.; Ma, Q.

2017-12-01

The environmental effect on the ionosphere caused by man-made power line emission (PLE) and power line harmonic radiation (PLHR) has become an increasing concern. Based on the observed data of 6.5 operating years of DEMETER satellite, by scanning the electric field power density time-frequency spectrograms, 133 PLHR events with central frequencies from 500 Hz to 4.5 kHz are detected in the near-Earth space above China. Among the 133 events, 129 events have PLE events at the base power system frequency (50 Hz in China). The duration time of every PLE event covers that of the corresponding PLHR event totally. As the same with PLHR, PLE is also propagating in whistler mode in the ionosphere. In two events that are detected in the conjugate region of Australian NWC VLF transmitter, radiations with line structure in the vicinity of 19.8 kHz are detected. There are 5 lines distributed from about 19.7 kHz to 19.9 kHz, which are in accordance with the frequency range of NWC transmitted signals. The frequency spacing of the 5 lines is exactly 50 Hz and the bandwidth of each line is about 10 Hz. The electric field power density of the line structure radiation is at the same level with the corresponding PLE, much higher than that of PLHR. The line structure radiations suggest possible modulation of VLF signals by PLE. At last, the variation of ionospheric parameters measured by DEMETER in relation with PLHR is analyzed statistically. As the revisiting orbits of DEMETER pass over the same area with nearly no deviation and at the same time of day, for each PLHR event, we check and average the parameters of 3 revisiting orbits before and after the event respectively. Combined with the event orbit, the variations of these parameters can be obtained. There are totally 5 tendencies: no variation, ascending, descending, crest and trough. Only a few events show no variation. Though there are differences in other 4 tendencies, none of the parameters show extremely preferences on one of the 4 tendencies. The crest and trough events are generally more than ascending and descending events, especially for ion density and O+ ion percentage. The variations of parameters show no preferences on latitude and the day of year.

Plutonium activities and 240Pu/ 239Pu atom ratios in sediment cores from the east China sea and Okinawa Trough: Sources and inventories

NASA Astrophysics Data System (ADS)

Wang, Zhong-liang; Yamada, Masatoshi

2005-05-01

Plutonium concentrations and 240Pu/ 239Pu atom ratios in the East China Sea and Okinawa Trough sediment cores were determined by isotope dilution inductively coupled plasma mass spectrometry after separation using ion-exchange chromatography. The results showed that 240Pu/ 239Pu atom ratios in the East China Sea and Okinawa Trough sediments, ranging from 0.21 to 0.33, were much higher than the reported value of global fallout (0.18). The highest 240Pu/ 239Pu ratios (0.32-0.33) were observed in the deepest Okinawa Trough sediment samples. These ratios suggested the US nuclear weapons tests in the early 1950s at the Pacific Proving Grounds in the Marshall Islands were a major source of plutonium in the East China Sea and Okinawa Trough sediments, in addition to the global fallout source. It was proposed that close-in fallout plutonium was delivered from the Pacific Proving Grounds test sites via early direct tropospheric fallout and transportation by the North Pacific Equatorial Circulation system and Kuroshio Current into the Okinawa Trough and East China Sea. The total 239 + 240 Pu inventories in the cores were about 150-200% of that expected from direct global fallout; about 46-67% of the total inventories were delivered from the Pacific Proving Grounds. Much higher 239 + 240 Pu inventories were observed in the East China Sea sediments than in sediments of the Okinawa Trough, because in the open oceans, part of the 239 + 240 Pu was still retained in the water column, and continued Pu scavenging was higher over the margin than the trough. According to the vertical distributions of 239 + 240 Pu activities and 240Pu/ 239Pu atom ratios in these cores, it was concluded that sediment mixing was the dominant process in controlling profiles of plutonium in this area. Faster mixing in the coastal samples has homogenized the entire 240Pu/ 239Pu ratio record today; slightly slower mixing and less scavenging in the Okinawa Trough have left the surface sediment ratios closer to the modern North Pacific water end member and higher ratios (0.30-0.34) at the bottom of the cores.

Waveform anomaly caused by strong attenuation in the crust and upper mantle in the Okinawa Trough region

NASA Astrophysics Data System (ADS)

Padhy, S.; Furumura, T.; Maeda, T.

2017-12-01

The Okinawa Trough is a young continental back-arc basin located behind the Ryukyu subduction zone in southwestern Japan, where the Philippine Sea Plate dives beneath the trough, resulting in localized mantle upwelling and crustal thinning of the overriding Eurasian Plate. The attenuation structure of the plates and surrounding mantle in this region associated with such complex tectonic environment are poorly documented. Here we present seismological evidence for these features based on the high-resolution waveform analyses and 3D finite difference method (FDM) simulation. We analyzed regional broadband waveforms recorded by F-net (NIED) of in-slab events (M>4, H>100 km). Using band-passed (0.5-8 Hz), mean-squared envelopes, we parameterized coda-decay in terms of rise-time (time from P-arrival to maximum amplitude in P-coda), decay-time (time from maximum amplitude to theoretical S-arrival), and energy-ratio defined as the ratio of energy in P-coda to that in direct P wave. The following key features are observed. First, there is a striking difference in S-excitation along paths traversing and not traversing the trough: events from SW Japan not crossing the trough show clear S waves, while those occurring in the trough show very weak S waves at a station close to the volcanic front. Second, some trough events exhibit spindle-shaped seismograms with strong P-coda excitation, obscuring the development of S waves, at back-arc stations; these waveforms are characterized by high decay-time (>10s) and high energy-ratio (>>1.0), suggesting strong forward scattering along ray paths. Third, some trough events show weak S-excitation characterized by low decay-time (<5s) and low energy-ratio (<1.0) at fore-arc stations, suggesting high intrinsic absorption. To investigate the mechanism of the observed anomalies, we will conduct FDM simulation for a suite of models comprising the key subduction features like localized mantle-upwelling and crustal thinning expected in the region. It is expected that simulation results help to resolve rift-induced crust and upper mantle anomalies in the trough showing maximum waveform distortion as we observed in broadband records, and will enhance understanding of tectonic processes related to back-arc rifting in the region.

Habitat use by larval fishes in a temperate South African surf zone

NASA Astrophysics Data System (ADS)

Watt-Pringle, Peter; Strydom, Nadine A.

2003-12-01

Larval fishes were sampled in the Kwaaihoek surf zone on the south east coast of South Africa. On six occasions between February and May 2002, larval fishes were collected in two habitat types identified in the inner surf zone using a modified beach-seine net. The surf zone habitats were classified as either sheltered trough areas or adjacent exposed surf areas. Temperature, depth and current measurements were taken at all sites. Trough habitats consisted of a depression in surf topography characterised by reduced current velocities and greater average depth than adjacent surf areas. In total, 325 larval fishes were collected. Of these, 229 were collected in trough and 96 in surf habitats. At least 22 families and 37 species were represented in the catch. Dominant families were the Mugilidae, Sparidae, Atherinidae, and Engraulidae. Dominant species included Liza tricuspidens and Liza richardsonii (Mugilidae), Rhabdosargus holubi and Sarpa salpa (Sparidae), Atherina breviceps (Atherinidae) and Engraulis japonicus (Engraulide). Mean CPUE of postflexion larvae of estuary-dependent species was significantly greater in trough areas. The proportion of postflexion larval fishes in trough habitat was significantly greater than that of preflexion stages, a result that was not apparent in surf habitat sampled. CPUE of postflexion larvae of estuary-dependent fishes was negatively correlated with current magnitude and positively correlated with habitat depth. Mean body length of larval fishes was significantly greater in trough than in surf habitats. These results provide evidence that the CPUE of postflexion larvae of estuary-dependent fishes is higher in trough habitat in the surf zone and this may be indicative of active habitat selection for areas of reduced current velocity/wave action. The implications of this behaviour for estuarine recruitment processes are discussed.

Summary of engineering-scale experiments for the Solar Detoxification of Water project

NASA Astrophysics Data System (ADS)

Pacheco, J. E.; Yellowhorse, L.

1992-03-01

This report contains a summary of large-scale experiments conducted at Sandia National Laboratories under the Solar Detoxification of Water project. The objectives of the work performed were to determine the potential of using solar radiation to destroy organic contaminants in water by photocatalysis and to develop the process and improve its performance. For these experiments, we used parabolic troughs to focus sunlight onto glass pipes mounted at the trough's focus. Water spiked with a contaminant and containing suspended titanium dioxide catalyst was pumped through the illuminated glass pipe, activating the catalyst with the ultraviolet portion of the solar spectrum. The activated catalyst creates oxidizers that attack and destroy the organics. Included in this report are a summary and discussion of the implications of experiments conducted to determine: the effect of process kinetics on the destruction of chlorinated solvents (such as trichloroethylene, perchloroethylene, trichloroethane, methylene chloride, chloroform and carbon tetrachloride), the enhancement due to added hydrogen peroxide, the optimal catalyst loading, the effect of light intensity, the inhibition due to bicarbonates, and catalyst issues.

The origin of polygonal troughs on the northern plains of Mars

NASA Astrophysics Data System (ADS)

Pechmann, J. C.

1980-05-01

The morphology, distribution, geologic environment and relative age of large-scale polygonal trough systems on Mars are examined. The troughs are steep-walled, flat-floored, sinuous depressions typically 200-800 m wide, 20-120 m deep and spaced 5-10 km apart. The mechanics of formation of tension cracks is reviewed to identify the factors controlling the scale of tension crack systems; special emphasis is placed on thermal cracking in permafrost. It is shown that because of the extremely large scale of the Martian fracture systems, they could not have formed by thermal cracking in permafrost, dessication cracking in sediments or contraction cracking in cooling lava. On the basis of photogeologic evidence and analog studies, it is proposed that polygonal troughs on the northern plains of Mars are grabens.

GAS SEAL

DOEpatents

Monson, H.; Hutter, E.

1961-07-11

A seal is described for a cover closing an opening in the top of a pressure vessel that may house a nuclear reactor. The seal comprises a U-shaped trough formed on the pressure vessel around the opening therein, a mass of metal in the trough, and an edge flange on the cover extending loosely into the trough and dipping into the metal mass. The lower portion of the metal mass is kept melted, and the upper portion, solid. The solid pontion of the metal mass prevents pressure surges in the vessel from expelling the liquid portion of the metal mass from the trough; the liquld portion, thus held in place by the solid portion, does not allow gas to go through, and so gas cannot escape through shrinkage holes in the solid portion.

Method and apparatus for automatically detecting patterns in digital point-ordered signals

DOEpatents

Brudnoy, David M.

1998-01-01

The present invention is a method and system for detecting a physical feature of a test piece by detecting a pattern in a signal representing data from inspection of the test piece. The pattern is detected by automated additive decomposition of a digital point-ordered signal which represents the data. The present invention can properly handle a non-periodic signal. A physical parameter of the test piece is measured. A digital point-ordered signal representative of the measured physical parameter is generated. The digital point-ordered signal is decomposed into a baseline signal, a background noise signal, and a peaks/troughs signal. The peaks/troughs from the peaks/troughs signal are located and peaks/troughs information indicating the physical feature of the test piece is output.

Method and apparatus for automatically detecting patterns in digital point-ordered signals

DOEpatents

Brudnoy, D.M.

1998-10-20

The present invention is a method and system for detecting a physical feature of a test piece by detecting a pattern in a signal representing data from inspection of the test piece. The pattern is detected by automated additive decomposition of a digital point-ordered signal which represents the data. The present invention can properly handle a non-periodic signal. A physical parameter of the test piece is measured. A digital point-ordered signal representative of the measured physical parameter is generated. The digital point-ordered signal is decomposed into a baseline signal, a background noise signal, and a peaks/troughs signal. The peaks/troughs from the peaks/troughs signal are located and peaks/troughs information indicating the physical feature of the test piece is output. 14 figs.

Circadian rhythms in human performance and mood under constant conditions

NASA Technical Reports Server (NTRS)

Monk, T. H.; Buysse, D. J.; Reynolds, C. F. 3rd; Berga, S. L.; Jarrett, D. B.; Begley, A. E.; Kupfer, D. J.

1997-01-01

This study explored the relationship between circadian performance rhythms and rhythms in rectal temperature, plasma cortisol, plasma melatonin, subjective alertness and well-being. Seventeen healthy young adults were studied under 36 h of 'unmasking' conditions (constant wakeful bedrest, temporal isolation, homogenized 'meals') during which rectal temperatures were measured every minute, and plasma cortisol and plasma melatonin measured every 20 min. Hourly subjective ratings of global vigour (alertness) and affect (well-being) were obtained followed by one of two performance batteries. On odd-numbered hours performance (speed and accuracy) of serial search, verbal reasoning and manual dexterity tasks was assessed. On even-numbered hours, performance (% hits, response speed) was measured at a 25-30 min visual vigilance task. Performance of all tasks (except search accuracy) showed a significant time of day variation usually with a nocturnal trough close to the trough in rectal temperature. Performance rhythms appeared not to reliably differ with working memory load. Within subjects, predominantly positive correlations emerged between good performance and higher temperatures and better subjective alertness; predominantly negative correlations between good performance and higher plasma levels of cortisol and melatonin. Temperature and cortisol rhythms correlated with slightly more performance measures (5/7) than did melatonin rhythms (4/7). Global vigour correlated about as well with performance (5/7) as did temperature, and considerably better than global affect (1/7). In conclusion: (1) between-task heterogeneity in circadian performance rhythms appeared to be absent when the sleep/wake cycle was suspended; (2) temperature (positively), cortisol and melatonin (negatively) appeared equally good as circadian correlates of performance, and (3) subjective alertness correlated with performance rhythms as well as (but not better than) body temperature, suggesting that performance rhythms were not directly mediated by rhythms in subjective alertness.

Southern Sand Dunes

NASA Image and Video Library

2003-01-15

At first glance, this NASA Mars Odyssey image showing impact craters and linear ridges and troughs is typical of the southern highlands. However, upon closer examination migrating sand dunes are observed within the troughs.

Volcanism and massive sulfide formation at a sedimented spreading center, Escanaba Trough, Gorda Ridge, northeast Pacific.

USGS Publications Warehouse

Morton, J.L.; Holmes, M.L.; Koski, R.A.

1987-01-01

Seismic-reflection profiles over the sediment-filled Escanaba Trough at the southern Gorda Ridge reveal a series of volcanic centers that pierce the sediment. The volcanic edifices are 3 to 6 km in diameter and are spaced at 15 to 20 km intervals along the axis of the trough. Composition and form of sulfide samples obtained from the bank suggest significant interaction between hydrothermal fluids and sediment at depth, and deposition of sulfide within the sediment pile.-from Authors

Case study: A severe hailstorm and strong downbursts over northeastern Slovenia on June 16th 2009

NASA Astrophysics Data System (ADS)

Korosec, M.

2009-09-01

Introduction A strong isolated storm complex with bow echo feature crossed northeastern Slovenia in the late afternoon hours and caused extensive damage due to severe wind gusts near 30m/s, excessive rainfalls and large hail. Synoptic situation On June 16th 2009, an upper-level ridge persists over southern Europe while a positively tilted short-wave trough, connected to a complex deep trough over northern Europe, crosses central Europe. Accompanied by this trough, a cold front is extending southwestwards towards the Alps. A relatively strong jet steak wraps around the trough axis and creates strong shear environment which overlaps with a narrow band of unstable airmass present ahead of the coming frontal boundary. Behind this trough/front over central Europe, a high pressure area is developing with stable conditions. Over Slovenia, strong surface heating was on going through the day but lack of near-surface convergence zones, limited moisture and strong capping inversion surpressed any storm initiation in the afternoon. Presentation of research This case study will go through a research of damaging bow echo which caused extensive damage due to severe winds, excessive rainfalls and large hail over much of northeastern Slovenia. Numerous trees were down or uprooted and numerous roofs were blown off or were seriously damaged due to severe wind gusts near or exceeding 30m/s. At first stages, when an isolated severe storm entered Slovenia, it had classic high precipitation supercell features while it transformed into a powerful bow echo later on. Very large hail up to 6cm in diameter was first observed in southeast Austria and near the border with Slovenia, while later on the main threat was very strong wind gusts and intense rainfalls. This research paper will show a detailed analysis of the synoptic situation including analysis of satellite, radar and surface observations. Radar imagery clearly showed isolated storm trailing along the near-surface frontal boundary as a bow echo and also satellite imagery showed signs of extremely severe storm as overshooting tops, "cold ring" and "U-shape" features were observed. References - Skywarn Austria forum: (http://www.skywarn.at/forum/) - EARS radar and SFC observations archive (http://www.arso.gov.si) - EARS article: Porocilo o neurjih 16. junija 2009 - OSMER FVG (http://www.meteo.fvg.it) - ESSL/ESWD database (www.essl.org) - ESTOFEX convective maps (www.estofex.org) - EUMETSAT satellite imagery (www.eumetsat.int) - 24ur.com/RTVSLO web portal (www.24ur.com, www.rtvslo.si) - Sobota Info web portal (www.sobotainfo.com) - Pomurje web portal (www.pomurje.si) - Administration of the Republic of Slovenia for Civil Protection and Disaster Relief, www.sos112.si - Worldwide Skew-t diagrams (http://weather.uwyo.edu/upperair/europe.html)

Experimental and numerical study of latent heat thermal energy storage systems assisted by heat pipes for concentrated solar power application

NASA Astrophysics Data System (ADS)

Tiari, Saeed

A desirable feature of concentrated solar power (CSP) with integrated thermal energy storage (TES) unit is to provide electricity in a dispatchable manner during cloud transient and non-daylight hours. Latent heat thermal energy storage (LHTES) offers many advantages such as higher energy storage density, wider range of operating temperature and nearly isothermal heat transfer relative to sensible heat thermal energy storage (SHTES), which is the current standard for trough and tower CSP systems. Despite the advantages mentioned above, LHTES systems performance is often limited by low thermal conductivity of commonly used, low cost phase change materials (PCMs). Research and development of passive heat transfer devices, such as heat pipes (HPs) to enhance the heat transfer in the PCM has received considerable attention. Due to its high effective thermal conductivity, heat pipe can transport large amounts of heat with relatively small temperature difference. The objective of this research is to study the charging and discharging processes of heat pipe-assisted LHTES systems using computational fluid dynamics (CFD) and experimental testing to develop a method for more efficient energy storage system design. The results revealed that the heat pipe network configurations and the quantities of heat pipes integrated in a thermal energy storage system have a profound effect on the thermal response of the system. The optimal placement of heat pipes in the system can significantly enhance the thermal performance. It was also found that the inclusion of natural convection heat transfer in the CFD simulation of the system is necessary to have a realistic prediction of a latent heat thermal storage system performance. In addition, the effects of geometrical features and quantity of fins attached to the HPs have been studied.

A population pharmacokinetic model of valproic acid in pediatric patients with epilepsy: a non-linear pharmacokinetic model based on protein-binding saturation.

PubMed

Ding, Junjie; Wang, Yi; Lin, Weiwei; Wang, Changlian; Zhao, Limei; Li, Xingang; Zhao, Zhigang; Miao, Liyan; Jiao, Zheng

2015-03-01

Valproic acid (VPA) follows a non-linear pharmacokinetic profile in terms of protein-binding saturation. The total daily dose regarding VPA clearance is a simple power function, which may partially explain the non-linearity of the pharmacokinetic profile; however, it may be confounded by the therapeutic drug monitoring effect. The aim of this study was to develop a population pharmacokinetic model for VPA based on protein-binding saturation in pediatric patients with epilepsy. A total of 1,107 VPA serum trough concentrations at steady state were collected from 902 epileptic pediatric patients aged from 3 weeks to 14 years at three hospitals. The population pharmacokinetic model was developed using NONMEM(®) software. The ability of three candidate models (the simple power exponent model, the dose-dependent maximum effect [DDE] model, and the protein-binding model) to describe the non-linear pharmacokinetic profile of VPA was investigated, and potential covariates were screened using a stepwise approach. Bootstrap, normalized prediction distribution errors and external evaluations from two independent studies were performed to determine the stability and predictive performance of the candidate models. The age-dependent exponent model described the effects of body weight and age on the clearance well. Co-medication with carbamazepine was identified as a significant covariate. The DDE model best fitted the aim of this study, although there were no obvious differences in the predictive performances. The condition number was less than 500, and the precision of the parameter estimates was less than 30 %, indicating stability and validity of the final model. The DDE model successfully described the non-linear pharmacokinetics of VPA. Furthermore, the proposed population pharmacokinetic model of VPA can be used to design rational dosage regimens to achieve desirable serum concentrations.

Investigation of a high power electromagnetic pulse source.

PubMed

Wang, Yuwei; Chen, Dongqun; Zhang, Jiande; Cao, Shengguang; Li, Da; Liu, Chebo

2012-09-01

A high power electromagnetic pulse source with a resonant antenna driven by a compact power supply was investigated in this paper. To match the impedance of the resonant antenna and initial power source, a compact power conditioning circuit based on electro exploding opening switch (EEOS) and pulsed transformer was adopted. In the preliminary experiments, an impulse capacitor was used to drive the system. With the opening of the EEOS at the current of 15 kA flowing trough the primary of the transformer, the resonant antenna was rapidly charged to about -370 kV within a time of about 100 ns. When the switch in the resonant antenna closed at the charging voltage of about -202 kV, the peak intensity of the detected electric field at a distance of about 10 m from the center of the source was 7.2 kV∕m. The corresponding peak power of the radiated electromagnetic field reached 76 MW, while the total radiated electromagnetic energy was about 0.65 J. The total energy efficiency of the resonant antenna was about 22% which can be improved by increasing the closing rapidity of the switch in the antenna.

Stable interior, showing center aisle, stalls, and feed troughs. View ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

Stable interior, showing center aisle, stalls, and feed troughs. View looking southwest - Fort Hill Farm, Stable, West of Staunton (Roanoke) River between Turkey & Caesar's Runs, Clover, Halifax County, VA

Heat transfer enhancement in a parabolic trough solar receiver using longitudinal fins and nanofluids

NASA Astrophysics Data System (ADS)

Amina, Benabderrahmane; Miloud, Aminallah; Samir, Laouedj; Abdelylah, Benazza; Solano, J. P.

2016-10-01

In this paper, we present a three dimensional numerical investigation of heat transfer in a parabolic trough collector receiver with longitudinal fins using different kinds of nanofluid, with an operational temperature of 573 K and nanoparticle concentration of 1% in volume. The outer surface of the absorber receives a non-uniform heat flux, which is obtained by using the Monte Carlo ray tracing technique. The numerical results are contrasted with empirical results available in the open literature. A significant improvement of heat transfer is derived when the Reynolds number varies in the range 2.57×104 ≤ Re ≤ 2.57×105, the tube-side Nusselt number increases from 1.3 to 1.8 times, also the metallic nanoparticles improve heat transfer greatly than other nanoparticles, combining both mechanisms provides better heat transfer and higher thermo-hydraulic performance.

Decadal Modulation of Repeating Slow Slip Event Activity in the Southwestern Ryukyu Arc Possibly Driven by Rifting Episodes at the Okinawa Trough

NASA Astrophysics Data System (ADS)

Tu, Yoko; Heki, Kosuke

2017-09-01

We studied 38 slow slip events (SSEs) in 1997-2016 beneath the Iriomote Island, southwestern Ryukyu Arc, Japan, using continuous Global Navigation Satellite Systems data. These SSEs occur biannually on the same fault patch at a depth of 30 km on the subducting Philippine Sea Plate slab with average moment magnitudes (Mw) of 6.6. Here we show that the slip accumulation rate (cumulative slip/lapse time) of these SSEs fluctuated over a decadal time scale. The rate increased twice around 2002 and 2013 concurrently with earthquake swarms in the Okinawa Trough. This suggests that episodic activations of the back-arc spreading at the Okinawa Trough caused extra southward movement of the block south of the trough and accelerated convergence at the Ryukyu Trench.

Surface expression of the Chicxulub crater

PubMed

Pope, K O; Ocampo, A C; Kinsland, G L; Smith, R

1996-06-01

Analyses of geomorphic, soil, and topographic data from the northern Yucatan Peninsula, Mexico, confirm that the buried Chicxulub impact crater has a distinct surface expression and that carbonate sedimentation throughout the Cenozoic has been influenced by the crater. Late Tertiary sedimentation was mostly restricted to the region within the buried crater, and a semicircular moat existed until at least Pliocene time. The topographic expression of the crater is a series of features concentric with the crater. The most prominent is an approximately 83-km-radius trough or moat containing sinkholes (the Cenote ring). Early Tertiary surfaces rise abruptly outside the moat and form a stepped topography with an outer trough and ridge crest at radii of approximately 103 and approximately 129 km, respectively. Two discontinuous troughs lie within the moat at radii of approximately 41 and approximately 62 km. The low ridge between the inner troughs corresponds to the buried peak ring. The moat corresponds to the outer edge of the crater floor demarcated by a major ring fault. The outer trough and the approximately 62-km-radius inner trough also mark buried ring faults. The ridge crest corresponds to the topographic rim of the crater as modified by postimpact processes. These interpretations support previous findings that the principal impact basin has a diameter of approximately 180 km, but concentric, low-relief slumping extends well beyond this diameter and the eroded crater rim may extend to a diameter of approximately 260 km.

Comparative analyses of the bacterial community of hydrothermal deposits and seafloor sediments across Okinawa Trough

NASA Astrophysics Data System (ADS)

Wang, Long; Yu, Min; Liu, Yan; Liu, Jiwen; Wu, Yonghua; Li, Li; Liu, Jihua; Wang, Min; Zhang, Xiao-Hua

2018-04-01

As an ideal place to study back-arc basins and hydrothermal eco-system, Okinawa Trough has attracted the interests of scientists for decades. However, there are still no in-depth studies targeting the bacterial community of the seafloor sediments and hydrothermal deposits in Okinawa Trough. In the present study, we reported the bacterial community of the surface deposits of a newly found hydrothermal field in the southern Okinawa Trough, and the horizontal and vertical variation of bacterial communities in the sediments of the northern Okinawa Trough. The hydrothermal deposits had a relatively high 16S rRNA gene abundance but low bacterial richness and diversity. Epsilonproteobacteria and Bacteroidetes were predominant in hydrothermal deposits whereas Deltaproteobacteria, Gammaproteobacteria and Chloroflexi were abundant across all samples. The bacterial distribution in the seafloor of Okinawa Trough was significantly correlated to the content of total nitrogen, and had consistent relationship with total carbon. Gradual changes of sulfur-oxidizing bacteria were found with the distance away from hydrothermal fields, while the hydrothermal activity did not influence the distribution of the major clades of sulfate-reducing bacteria. Higher abundance of the sulfur cycle related genes (aprA and dsrB), and lower abundance of the bacterial ammonia-oxidizing related gene (amoA) were quantified in hydrothermal deposits. In addition, the present study also compared the inter-field variation of Epsilonproteobacteria among multi-types of hydrothermal vents, revealing that the proportion and diversity of this clade were quite various.

New details about the LGM extent and subsequent retreat of the West Antarctic Ice Sheet from the easternmost Amundsen Sea Embayment shelf

NASA Astrophysics Data System (ADS)

Klages, J. P.; Hillenbrand, C. D.; Kuhn, G.; Smith, J. A.; Graham, A. G. C.; Nitsche, F. O.; Frederichs, T.; Arndt, J. E.; Gebhardt, C.; Robin, Z.; Uenzelmann-Neben, G.; Gohl, K.; Jernas, P.; Wacker, L.

2017-12-01

In recent years several previously undiscovered grounding-zone wedges (GZWs) have been described within the Abbot-Cosgrove palaeo-ice stream trough on the easternmost Amundsen Sea Embayment shelf. These GZWs document both the Last Glacial Maximum (LGM; 26.5-19 cal. ka BP) grounding-line extent and the subsequent episodic retreat within this trough that neighbors the larger Pine Island-Thwaites trough to the west. Here we combine bathymetric, seismic, and geologic data showing that 1) the grounding line in Abbot Trough did not reach the continental shelf break at any time during the last glacial period, and 2) a prominent stacked GZW constructed from six individual wedges lying upon another was deposited 100 km upstream from the LGM grounding-line position. The available data allow for calculating volumes for most of these individual GZWs and for the entire stack. Sediment cores were recovered seawards from the outermost GZW in the trough, and from the individual wedges of the stacked GZW in order to define the LGM grounding-line extent, and provide minimum grounding-line retreat ages for the respective positions on the stacked GZW. We present implications of a grounded-ice free outer shelf throughout the last glacial period. Furthermore, we assess the significance of the grounding-line stillstand period recorded by the stacked GZW in Abbot Trough for the timing of post-LGM retreat of the West Antarctic Ice Sheet from the Amundsen Sea Embayment shelf.

Observations and simulations of the bottom nepheloid layer in the Lafourche Trough, Louisiana Continental Shelf

NASA Astrophysics Data System (ADS)

Jolliff, J.; Jarosz, E.; Penko, A.; Smith, T.

2017-12-01

The "Lafourche Trough" is a mud/silt -dominated, elongate seafloor depression located between transgressive sandy shoals approximately 50 km south of Cocodrie, Louisiana. These irregular bathymetric features are relicts of the abandoned Lafourche delta complex that still have an impact upon coupled sediment-hydrodynamic processes occurring today. Repeated optical and physical oceanographic surveys conducted during the spring of 2015 and winter 2017 reveal persistent bottom nepheloid layers (BNLs) characterized by extreme optical turbidity (beam attenuation 10 m-1, 532 nm). The manifestation and persistence of cohesive sediment BNLs in this area appears to result from a complex interplay between tidal currents, bathymetry, and frontal dynamics along the edge of the Mississippi River plume. Numerical experiments were performed using the Coupled Ocean Atmosphere Mesoscale Prediction System (COAMPS), an integrated air-sea-wave operational forecasting tool, that includes a simplified numerical sediment resuspension and transport scheme in order to simulate the nepheloid layer observations through the trough. The model results suggest that the wave-current bottom boundary layer is a critical factor in BNL development, and thusly, without wave model integration into COAMPS the system struggles to replicate the observations. Future modeling work will need to explore the potential suppression of physical mixing due to density perturbations along the BNL to fluid mud continuum within the bottom boundary layer.

A Retrospective Study of Amitriptyline in Youth with Autism Spectrum Disorders

ERIC Educational Resources Information Center

Bhatti, Irfan; Thome, Andrew; Smith, Patricia Oxler; Cook-Wiens, Galen; Yeh, Hung Wen; Gaffney, Gary R.; Hellings, Jessica A.

2013-01-01

We performed a retrospective chart review of 50 youths with Autism Spectrum Disorder (ASD), prescribed amitriptyline (AMI) for hyperactivity and impulsivity. Data was systematically extracted from 50 outpatient clinic charts, including AMI treatment duration, dose, trough levels and adverse events. Mean age was 9.4 years (4.6-17.9); 40 were males…

Landslides in Valles Marineris, Mars

NASA Technical Reports Server (NTRS)

Lucchitta, B. K.

1979-01-01

The morphology of the landslides in the Martian equatorial troughs, the geologic structure of the troughs, the time of emplacement, the similarity to terrestrial landslides, and the origin and mechanism of transport are analyzed. About 35 large landslides well-resolved on Viking images were examined, and it is found that the major landslides cover 31,000 sq km of the trough floors, and individual slides range in area from 40 to 7000 sq km. The morphologic variations of the landslides can be attributed mainly to their degree of confinement on trough floors. Many prominent landslides appear to be of similar age and were emplaced after a major faulting that dropped the trough floors. Most sliding occurred after the created scarps were dissected into spurs, gullies, and tributary canyons. Emplacement of the landslides approximately coincided with a late episode of major eruptive activity of the Tharsis volcanoes, and it is suggested that the slides may have originated as gigantic mudflows with slump blocks at their heads. The large size of many landslides is due to the fault scarps as high as 7 km on which they formed in the absence of vigorous fluvial erosion. The landslides suggest that Mars is earthlike in some respects, which may be important for further evaluations.

Morphology-dependent water budgets and nutrient fluxes in arctic thaw ponds

USGS Publications Warehouse

Koch, Joshua C.; Gurney, Kirsty; Wipfli, Mark S.

2014-01-01

Thaw ponds on the Arctic Coastal Plain of Alaska are productive ecosystems, providing habitat and food resources for many fish and bird species. Permafrost in this region creates unique pond morphologies: deep troughs, shallow low-centred polygons (LCPs) and larger coalescent ponds. By monitoring seasonal trends in pond volume and chemistry, we evaluated whether pond morphology and size affect water temperature and desiccation, and nitrogen (N) and phosphorus (P) fluxes. Evaporation was the largest early-summer water flux in all pond types. LCPs dried quickly and displayed high early-summer nutrient concentrations and losses. Troughs consistently received solute-rich subsurface inflows, which accounted for 12 to 42 per cent of their volume and may explain higher P in the troughs. N to P ratios increased and ammonium concentrations decreased with pond volume, suggesting that P and inorganic N availability may limit ecosystem productivity in older, larger ponds. Arctic summer temperatures will likely increase in the future, which may accelerate mid-summer desiccation. Given their morphology, troughs may remain wet, become warmer and derive greater nutrient loads from their thawing banks. Overall, seasonal- to decadal-scale warming may increase ecosystem productivity in troughs relative to other Arctic Coastal Plain ponds. 

A simple model of the effects of the mid-latitude total ion trough in the bottomside F layer on HF radiowave propagation

NASA Astrophysics Data System (ADS)

Lockwood, M.

1981-06-01

Observations of the amplitudes and Doppler shifts of received HF radio waves are compared with model predictions made using a two-dimensional ray-tracing program. The signals are propagated over a sub-auroral path, which is shown to lie along the latitudes of the mid-latitude trough at times of low geomagnetic activity. Generalizing the predictions to include a simple model of the trough in the density and height of the F2 peak enables the explanation of the anomalous observed diurnal variations. The behavior of received amplitude, Doppler shift, and signal-to-noise ratio as a function of the K sub p index value, the time of day, and the season (in 17 months of continuous recording) is found to agree closely with that predicted using the statistical position of the trough as deduced from 8 years of Alouette satellite soundings. The variation in the times of the observation of large signal amplitudes with the K sub p value and the complete absence of such amplitudes when it exceeds 2.75 are two features that implicate the trough in these effects.

Impact of Serum Vancomycin Trough Levels in the Treatment of Central Nervous System Shunt Infections Caused by Coagulase-Negative Staphylococci.

PubMed

Gibson, Ashley; Kaplan, Sheldon L; Vallejo, Jesus G

2018-04-26

Coagulase-negative staphylococci (CoNS) are a common cause of pediatric ventricular shunt infections. The Infectious Diseases Society of America recommends vancomycin serum troughs of 15-20 µg/mL when treating CoNS shunt infections in adult patients. We report a series of pediatric cases of CoNS shunt infections in which clinical cure was obtained with troughs < 15 µg/mL. These findings question the relevance of this recommendation in pediatric patients. © 2018 S. Karger AG, Basel.

A meta-analysis of clinical electro-oculography values.

PubMed

Constable, Paul A; Ngo, David; Quinn, Stephen; Thompson, Dorothy A

2017-12-01

The aim of the meta-analysis was to derive a range of mean normal clinical electrooculogram (EOG) values from a systematic review of published EOG studies that followed the guidelines of the ISCEV standard for clinical electro-oculography. A systematic literature review was performed using four relevant databases limited to peer-reviewed articles in English between 1967 and February 2017. Studies reporting clinical EOG or FO normal values were included when the report used a standard 30° horizontal saccade, a retinal luminance of between 100 and 250 cd m -2 , and had > 10 subjects in their normative values. The search identified 1145 articles after duplicates were removed with subsequent screening of the abstracts excluding a further 1098, resulting in 47 full-text articles that were then assessed by the author (PC) with a final nine articles meeting the inclusion criteria. An overall effect estimate using inverse variance-weighted meta-analysis was performed to estimate the mean values for the light peak/dark trough ratio (LP:DT ratio) (dilated and undilated), the time to the LP, the amplitude of the LP, dark trough (DT) and the fast oscillation (FO) peak-to-trough ratio from the included studies. The mean dilated LP:DT ratio was 2.35 (95% CI 2.28-2.42); undilated LP:DT ratio was 2.37 (95% CI 2.28-2.45); LP amplitude was 835 (95% CI 631-1039) µV and the mean time to the LP being 8.2 (95% CI 7.7-8.7) min. The mean DT amplitude was 358 (95% CI 292-424) µV, and the mean FO peak-to-trough ratio was 1.13 (95% CI 1.11-1.16). The results of the LP/DT ratio are drawn from studies with a mean ± standard deviation (SD) age of 34.08 ± 12.93 years for dilated and 33.65 ± 12.28 years for undilated LP/DT ratios. The meta-analysis of EOG studies has generated a reference range of normal mean values for clinicians to refer to when using the ISCEV clinical EOG. It provides a potential method to generate similar data sets from published normal values in related visual electrophysiology tests.

3D Porosity Estimation of the Nankai Trough Sediments from Core-log-seismic Integration

NASA Astrophysics Data System (ADS)

Park, J. O.

2015-12-01

The Nankai Trough off southwest Japan is one of the best subduction-zone to study megathrust earthquake fault. Historic, great megathrust earthquakes with a recurrence interval of 100-200 yr have generated strong motion and large tsunamis along the Nankai Trough subduction zone. At the Nankai Trough margin, the Philippine Sea Plate (PSP) is being subducted beneath the Eurasian Plate to the northwest at a convergence rate ~4 cm/yr. The Shikoku Basin, the northern part of the PSP, is estimated to have opened between 25 and 15 Ma by backarc spreading of the Izu-Bonin arc. The >100-km-wide Nankai accretionary wedge, which has developed landward of the trench since the Miocene, mainly consists of offscraped and underplated materials from the trough-fill turbidites and the Shikoku Basin hemipelagic sediments. Particularly, physical properties of the incoming hemipelagic sediments may be critical for seismogenic behavior of the megathrust fault. We have carried out core-log-seismic integration (CLSI) to estimate 3D acoustic impedance and porosity for the incoming sediments in the Nankai Trough. For the CLSI, we used 3D seismic reflection data, P-wave velocity and density data obtained during IODP (Integrated Ocean Drilling Program) Expeditions 322 and 333. We computed acoustic impedance depth profiles for the IODP drilling sites from P-wave velocity and density data. We constructed seismic convolution models with the acoustic impedance profiles and a source wavelet which is extracted from the seismic data, adjusting the seismic models to observed seismic traces with inversion method. As a result, we obtained 3D acoustic impedance volume and then converted it to 3D porosity volume. In general, the 3D porosities show decrease with depth. We found a porosity anomaly zone with alteration of high and low porosities seaward of the trough axis. In this talk, we will show detailed 3D porosity of the incoming sediments, and present implications of the porosity anomaly zone for the megathrust fault behavior.

Regional circulation around Heard and McDonald Islands and through the Fawn Trough, central Kerguelen Plateau

NASA Astrophysics Data System (ADS)

van Wijk, Esmee M.; Rintoul, Stephen R.; Ronai, Belinda M.; Williams, Guy D.

2010-05-01

The fine-scale circulation around the Heard and McDonald Islands and through the Fawn Trough, Kerguelen Plateau, is described using data from three high-resolution CTD sections, Argo floats and satellite maps of chlorophyll a, sea surface temperature (SST) and absolute sea surface height (SSH). We confirm that the Polar Front (PF) is split into two branches over the Kerguelen Plateau, with the NPF crossing the north-eastern limits of our survey carrying 25 Sv to the southeast. The SPF was associated with a strong eastward-flowing jet carrying 12 Sv of baroclinic transport through the deepest part of Fawn Trough (relative to the bottom). As the section was terminated midway through the trough this estimate is very likely to be a lower bound for the total transport. We demonstrate that the SPF contributes to the Fawn Trough Current identified by previous studies. After exiting the Fawn Trough, the SPF crossed Chun Spur and continued as a strong north-westward flowing jet along the eastern flank of the Kerguelen Plateau before turning offshore between 50°S and 51.5°S. Measured bottom water temperatures suggest a deep water connection between the northern and southern parts of the eastern Kerguelen Plateau indicating that the deep western boundary current continues at least as far north as 50.5°S. Analysis of satellite altimetry derived SSH streamlines demonstrates a southward shift of both the northern and southern branches of the Polar Front from 1994 to 2004. In the direct vicinity of the Heard and McDonald islands, cool waters of southern origin flow along the Heard Island slope and through the Eastern Trough bringing cold Winter Water (WW) onto the plateau. Complex topography funnels flow through canyons, deepens the mixed layer and increases productivity, resulting in this area being the preferred foraging region for a number of satellite-tracked land-based predators.

Balancing vancomycin efficacy and nephrotoxicity: should we be aiming for trough or AUC/MIC?

PubMed

Patel, Karisma; Crumby, Ashley S; Maples, Holly D

2015-04-01

Sixty years later, the question that still remains is how to appropriately utilize vancomycin in the pediatric population. The Infectious Diseases Society of America published guidelines in 2011 that provide guidance for dosing and monitoring of vancomycin in adults and pediatrics. However, goal vancomycin trough concentrations of 15-20 μg/mL for invasive infections caused by methicillin-resistant Staphylococcus aureus were based primarily on adult pharmacokinetic and pharmacodynamic data that achieved an area under the curve to minimum inhibitory concentration ratio (AUC/MIC) of ≥400. Recent pediatric literature shows that vancomycin trough concentrations needed to achieve the target AUC/MIC are different than the adult goal troughs cited in the guidelines. This paper addresses several thoughts, including the role of vancomycin AUC/MIC in dosing strategies and safety monitoring, consistency in laboratory reporting, and future directions for calculating AUC/MIC in pediatrics.

Paleoenvironmental Assessment and Deglacial Chronology of the Onondaga Trough, Onondaga County, New York

USGS Publications Warehouse

Kappel, William M.; Teece, Mark A.

2007-01-01

Introduction The U.S. Geological Survey, in cooperation with the Onondaga Lake Partnership and Onondaga Environmental Institute, has been studying the hydrogeology of the Onondaga Trough since 2002 to determine the movement and concentration of naturally occurring brine in the glacial valley-fill aquifer. Numerous shallow and deep test holes have been drilled to determine the glacial and water-quality stratigraphy in the Onondaga Trough. Organic materials were recovered from the Onondaga Creek, Ninemile Creek, and Harbor Brook valleys, and from lakebed sediments in Onondaga Lake (fig. 1) and age-dated with carbon-isotope analysis techniques. This report summarizes the carbon-isotope data collected from 1996 through 2006 in the Onondaga Trough. The results of these analyses provide a means to understand the deglaciation of the watershed and the development of the watershed from barren glacial sediment to a forested ecosystem.

Formations in Context (or, what is it?)

NASA Image and Video Library

2018-04-02

This image from NASA's Mars Reconnaissance Orbiter is a close-up of a trough, along with channels draining into the depression. Some HiRISE images show strange-looking formations. Sometimes it helps to look at Context Camera images to understand the circumstances of a scene -- like this cutout from CTX 033783_1509 -- which here shows an impact crater with a central peak, and a collapse depression with concentric troughs just north of that peak. On the floor of the trough is some grooved material that we typically see in middle latitude regions where there has been glacial flow. These depressions with concentric troughs exist elsewhere on Mars, and their origins remain a matter of debate. NB: The Context Camera is another instrument onboard MRO, and it has a larger viewing angle than HiRISE, but less resolution capability than our camera. https://photojournal.jpl.nasa.gov/catalog/PIA22348

Effect of lensing non-Gaussianity on the CMB power spectra

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lewis, Antony; Pratten, Geraint, E-mail: antony@cosmologist.info, E-mail: geraint.pratten@gmail.com

2016-12-01

Observed CMB anisotropies are lensed, and the lensed power spectra can be calculated accurately assuming the lensing deflections are Gaussian. However, the lensing deflections are actually slightly non-Gaussian due to both non-linear large-scale structure growth and post-Born corrections. We calculate the leading correction to the lensed CMB power spectra from the non-Gaussianity, which is determined by the lensing bispectrum. Assuming no primordial non-Gaussianity, the lowest-order result gives ∼ 0.3% corrections to the BB and EE polarization spectra on small-scales. However we show that the effect on EE is reduced by about a factor of two by higher-order Gaussian lensing smoothing,more » rendering the total effect safely negligible for the foreseeable future. We give a simple analytic model for the signal expected from skewness of the large-scale lensing field; the effect is similar to a net demagnification and hence a small change in acoustic scale (and therefore out of phase with the dominant lensing smoothing that predominantly affects the peaks and troughs of the power spectrum).« less

Flight Experience from Space Photovoltaic Concentrator Arrays and its Implication on Terrestrial Concentrator Systems

NASA Technical Reports Server (NTRS)

Piszczor, Michael F., Jr.

2003-01-01

Nearly all photovoltaic solar arrays flown in space have used a planar (non- concentrating) design. However, there have been a few notable exceptions where photovoltaic concentrators have been tested and used as the mission s primary power source. Among these are the success experienced by the SCARLET (Solar Concentrator Array with Refractive Linear Element Technology) concept used to power NASA's Deep Space 1 mission and the problems encountered by the original Boeing 702 reflective trough concentrator design. This presentation will give a brief overview of past photovoltaic concentrator systems that have flown in space, specifically addressing the valuable lessons learned from flight experience, and other viable concentrator concepts that are being proposed for the future. The general trends of this flight experience will be noted and discussed with regard to its implications on terrestrial photovoltaic concentrator designs.

Interannual variation of springtime biomass burning in Indochina: Regional differences, associated atmospheric dynamical changes, and downwind impacts.

PubMed

Huang, Wan-Ru; Wang, Sheng-Hsiang; Yen, Ming-Cheng; Lin, Neng-Huei; Promchote, Parichart

2016-09-16

During March and April, widespread burning occurs across farmlands in Indochina in preparation for planting at the monsoon onset. The resultant aerosols impact the air quality downwind. In this study, we investigate the climatic aspect of the interannual variation of springtime biomass burning in Indochina and its correlation with air quality at Mt. Lulin in Taiwan using long-term (2005-2015) satellite and global reanalysis data. Based on empirical orthogonal function (EOF) analysis, we find that the biomass burning activities vary with two geographical regions: northern Indochina (the primary EOF mode) and southern Indochina (the secondary EOF mode). We determine that the variation of biomass burning over northern Indochina is significantly related with the change in aerosol concentrations at Mt. Lulin. This occurs following the change in the so-called India-Burma Trough in the lower and middle troposphere. When the India-Burma Trough is intensified, a stronger northwesterly wind (to the west of the trough) transports the dryer air from higher latitude into northern Indochina, and this promotes local biomass burning activities. The increase in upward motion to the east of the intensified India-Burma Trough lifts the aerosols, which are transported toward Taiwan by the increased low-level westerly jet. Further diagnoses revealed the connection between the India-Burma Trough and the South Asian jet's wave train pattern as well as the previous winter's El Niño - Southern Oscillation phase. This information highlights the role of the India-Burma Trough in modulating northern Indochina biomass burning and possibly predicting aerosol transport to East Asia on the interannual time scale.

Modelling geothermal conditions in part of the Szczecin Trough - the Chociwel area

NASA Astrophysics Data System (ADS)

Miecznik, Maciej; Sowiżdżał, Anna; Tomaszewska, Barbara; Pająk, Leszek

2015-09-01

The Chociwel region is part of the Szczecin Trough and constitutes the northeastern segment of the extended Szczecin-Gorzów Synclinorium. Lower Jurassic reservoirs of high permeability of up to 1145 mD can discharge geothermal waters with a rate exceeding 250 m3/h and temperatures reach over 90°C in the lowermost part of the reservoirs. These conditions provide an opportunity to generate electricity from heat accumulated in geothermal waters using binary ORC (Organic Rankine Cycle) systems. A numerical model of the natural state and exploitation conditions was created for the Chociwel area with the use of TOUGH2 geothermal simulator (i.e., integral finite-difference method). An analysis of geological and hydrogeothermal data indicates that the best conditions are found to the southeast of the town of Chociwel, where the bottom part of the reservoir reaches 3 km below ground. This would require drilling two new wells, namely one production and one injection. Simulated production with a flow rate of 275 m3/h, a temperature of 89°C at the wellhead, 30°C injection temperature and wells being 1.2 km separated from each other leads to a small temperature drop and moderate requirements for pumping power over a 50 years' time span. The ORC binary system can produce at maximum 592.5 kW gross power with the R227ea found as the most suitable working fluid. Geothermal brine leaving the ORC system with a temperature c. 53°C can be used for other purposes, namely mushroom growing, balneology, swimming pools, soil warming, de-icing, fish farming and for heat pumps.

Enhancing performance of PEM fuel cells: Using the Au nanoplatelet/Nafion interface to enable CO oxidation under ambient conditions

DOE PAGES

Li, Hongfei; Pan, Cheng; Zhao, Sijia; ...

2016-04-16

We developed a method for fabrication of Au nanoparticle platelets which can be coated onto the Nafion membranes of polymer electrolyte membrane (PEM) fuel cells simply by Langmuir–Blodgett (LB) trough lift off from the air water interface. By incorporating the coated membranes into fuel cells with one membrane electrode assembly (MEA) we enhanced the maximum power output by more than 50% when operated under ambient conditions. An enhancement of more than 200% was observed when 0.1% CO was incorporated into the H 2 input gas stream and minimal enhancement was observed when the PEM fuel cell was operated with 100%more » O 2 gas at the cathode, or when particles were deposited on the electrodes. Density function theory (DFT) calculations were carried out to understand the origin of improved output power. Au NPs with 3-atomic layer in height and 2 nm in size were constructed to model the experimentally synthesized Au NPs. Our results indicated that the Au NPs interacted synergistically with the SO 3 groups, attached at end of Nafion side chains, to reduce the energy barrier for the oxidation of CO occurring at the perimeter of the Au NPs, from 1.292 eV to 0.518 eV, enabling the reaction to occur at T<300 K.« less

The Development of an Open Hardware and Software System Onboard Unmanned Aerial Vehicles to Monitor Concentrated Solar Power Plants

PubMed Central

Mesas-Carrascosa, Francisco Javier; Verdú Santano, Daniel; Pérez Porras, Fernando; Meroño-Larriva, José Emilio; García-Ferrer, Alfonso

2017-01-01

Concentrated solar power (CSP) plants are increasingly gaining interest as a source of renewable energy. These plants face several technical problems and the inspection of components such as absorber tubes in parabolic trough concentrators (PTC), which are widely deployed, is necessary to guarantee plant efficiency. This article presents a system for real-time industrial inspection of CSP plants using low-cost, open-source components in conjunction with a thermographic sensor and an unmanned aerial vehicle (UAV). The system, available in open-source hardware and software, is designed to be employed independently of the type of device used for inspection (laptop, smartphone, tablet or smartglasses) and its operating system. Several UAV flight missions were programmed as follows: flight altitudes at 20, 40, 60, 80, 100 and 120 m above ground level; and three cruising speeds: 5, 7 and 10 m/s. These settings were chosen and analyzed in order to optimize inspection time. The results indicate that it is possible to perform inspections by an UAV in real time at CSP plants as a means of detecting anomalous absorber tubes and improving the effectiveness of methodologies currently being utilized. Moreover, aside from thermographic sensors, this contribution can be applied to other sensors and can be used in a broad range of applications where real-time georeferenced data visualization is necessary. PMID:28594353

The Development of an Open Hardware and Software System Onboard Unmanned Aerial Vehicles to Monitor Concentrated Solar Power Plants.

PubMed

Mesas-Carrascosa, Francisco Javier; Verdú Santano, Daniel; Pérez Porras, Fernando; Meroño-Larriva, José Emilio; García-Ferrer, Alfonso

2017-06-08

Concentrated solar power (CSP) plants are increasingly gaining interest as a source of renewable energy. These plants face several technical problems and the inspection of components such as absorber tubes in parabolic trough concentrators (PTC), which are widely deployed, is necessary to guarantee plant efficiency. This article presents a system for real-time industrial inspection of CSP plants using low-cost, open-source components in conjunction with a thermographic sensor and an unmanned aerial vehicle (UAV). The system, available in open-source hardware and software, is designed to be employed independently of the type of device used for inspection (laptop, smartphone, tablet or smartglasses) and its operating system. Several UAV flight missions were programmed as follows: flight altitudes at 20, 40, 60, 80, 100 and 120 m above ground level; and three cruising speeds: 5, 7 and 10 m/s. These settings were chosen and analyzed in order to optimize inspection time. The results indicate that it is possible to perform inspections by an UAV in real time at CSP plants as a means of detecting anomalous absorber tubes and improving the effectiveness of methodologies currently being utilized. Moreover, aside from thermographic sensors, this contribution can be applied to other sensors and can be used in a broad range of applications where real-time georeferenced data visualization is necessary.

Landslides in Valles Marineris, Mars.

USGS Publications Warehouse

Lucchitta, B.K.

1979-01-01

Large landslides in the Martian equatorial troughs have been investigated with respect to morphology, geologic structure of the troughs, time of emplacement, similarity to terrestrial landslides, and origin and mechanism of transport. The morphologic variations of the landslides can be attributed mainly to their degree of confinement on trough floors. The huge size of many landslides is due to their occurrence on fault scarps that may have attained several kilometers in height in the absence of vigorous fluvial erosion on Mars. The mechanical efficiency of the Martian landslides is high but in accord with predictions from large landslides on earth. -from Author

Baby Spider: Growth of a Martian Trough Network

NASA Image and Video Library

2016-12-20

This image from NASA Mars Reconnaissance Orbiter shows the growth of a branching network of troughs carved by thawing carbon dioxide over the span of three Martian years. This process is believed to also form larger radially patterned channel features known as Martian "spiders." The image is one of three taken by the High Resolution Imaging Science Experiment (HiRISE) camera on NASA's Mars Reconnaissance Orbiter and included in a report on the first detection of such troughs persisting and growing, from one Mars year to the next. An animation is available at http://photojournal.jpl.nasa.gov/catalog/PIA21257

Optimization of woven jute/glass fibre-reinforced polyester hybrid composite solar parabolic trough collector

NASA Astrophysics Data System (ADS)

Reddy, K. S.; Singla, Hitesh

2017-07-01

In the present work, structural analysis of 5.77m × 4m woven jute (J)/glass (G) fibre-reinforced polyester hybrid composite solar parabolic trough is carried out based on trough parameters to obtain the minimum RMS local slope deviation, termed as SDx value under gravity loading. The optimization is done by varying parameters viz. direction and size of reinforced conduits, stacking number and sequence of hybrid trough laminate at fibre orientation of Δθ=45° and Δθ=60° amongst the layers at 0° collector angle. The analysis revealed that the configuration in which the conduits are placed in both X and Y directions is preferred over other configurations to scale down the effect of wind loads. Furthermore it has been observed that laminate of the order [0°G/45°G/-45°J/90°J]s undergoes minimum surface deformation amongst all the other configurations at conduit reinforcement in both X and Y directions for a conduit thickness of 0.75 mm and radius of 10 mm and obtains the overall SDx value of 1.3492 mrad. The results shows that proposed trough model is very promising and evolves a cost effective system.

Investigating the reasons of variability in Si IV and C IV broad absorption line troughs of quasars

NASA Astrophysics Data System (ADS)

Stathopoulos, Dimitrios; Lyratzi, Evangelia; Danezis, Emmanuel; Antoniou, Antonios; Tzimeas, Dimitrios

2017-09-01

In this paper we analyze the C IV and Si IV broad absorption troughs of two BALQSOs (J101056.69+355833.3, J114548.38+393746.6) to the individual components they consist of. By analyzing a BAL trough to its components we have the advantage to study the variations of the individual absorbing systems in the line of sight and not just the variations of the whole absorption trough or the variations of selected portions of BAL troughs exhibiting changes. We find that the velocity shifts and FWHMs (Full Width at Half Maximum) of the individual components do not vary between an interval of six years. All variable components show changes in the optical depths at line centers which are manifested as variations in the EW (Equivalent Width) of the components. In both BALQSOs, over corresponding velocities, Si IV has higher incidence of variability than C IV. From our analysis, evidence is in favour of different covering fractions between C IV and Si IV. Finally, although most of our results favour the crossing cloud scenario as the cause of variability, there is also strong piece of evidence indicating changing ionization as the source of variability. Thus, a mixed situation where both physical mechanisms contribute to BAL variability is the most possible scenario.

[Successful cyclosporine treatment in 2 patients with refractory CIDP, involving monitoring of both AUC(0-4h) and trough levels].

PubMed

Takeuchi, Akiko; Shirai, Shinichi; Horiuchi, Kazuhiro; Takahashi, Ikuko; Matsushima, Masaaki; Hirotani, Makoto; Kano, Takahiro; Yabe, Ichiro; Matumoto, Akihisa; Sasaki, Hidenao

2012-01-01

Cyclosporine A (CYA) treatment has been reported to be probably useful for patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) that is resistant to conventional treatment. Although several studies have shown that appropriate area under the concentration-time curve (AUC) monitoring of CYA levels results in improved outcomes for refractory nephrotic syndrome patients, the importance of using AUC analysis for CIDP remains unclear. In this study, we measured both trough and AUC from 0 to 4 h (AUC(0-4 h)) levels of CYA in 2 patients with CIDP and compared the findings for the clinical parameters. On the basis of the CYA dosing recommendations for patients with nephrotic syndrome, we used a CYA concentration of 150 ng/ml for the trough level and an AUC(0-4 h) value of 2,500 ng/(ml·h). Patient 1 showed a significant increase in grip strength and a prolonged remission period. Patient 2 showed improvement in the modified Rankin scale and manual muscle test (MMT) scores. Monitoring both AUC(0-4 h) and trough levels of CYA seems to be a better option than monitoring the trough level alone because it leads to improved estimation of the efficacy and safety of CYA treatment in the case of CIDP patients.

O+ trough zones in the polar cap ionosphere-magnetosphere coupling region

NASA Astrophysics Data System (ADS)

Horwitz, James; Zeng, Wen; Jaafari, Fajer

Regions of low-density troughs in O+ have been observed at 1 RE altitude in the polar cap ionosphere-magnetosphere region by the Thermal Ion Dynamics Experiment(TIDE) on the POLAR spacecraft. In this presentation, the UT Arlington Dynamic Fluid-Kinetic (DyFK) code is employed to investigate the formation of such O+ density troughs. We utilize convection paths of flux tubes in the high-latitude region as prescribed by an empirical convection model with solar wind inputs to track the evolution of ionospheric plasma transport and in particular O+ densities along these tubes with time/space. The flux tubes are subjected to auroral processes of precipitation and wave-driven ion heating when they pass through the auroral oval, which tends to elevate the plasma densities in these tubes. When the F-regions of such tubes traverse locations where the F-region is in darkness, recombination there causes the higher-altitude regions to drain and the densities to decline throughout. Owing to the varying effects of these processes, significant and low trough-like densities at higher altitudes developed along these flux tubes. The modeled densities near 6000 km altitudes will be compared with multiple POLAR passes featuring POLAR/TIDE-measured O+ densities for inside and outside of such trough regions.

Borehole instability analysis for IODP Site C0002 of the NanTroSEIZE Project, Nankai Trough subduction zone

NASA Astrophysics Data System (ADS)

Wu, H.; Kido, Y. N.; Kinoshita, M.; Saito, S.

2013-12-01

Wellbore instability is a major challenge for the engineer evaluating borehole and formation conditions. Instability is especially important to understand in areas with high stress variations, significant structure anisotropy, or pre-existing fracture systems. Borehole (in)stability is influenced by rock strength, structural properties, and near-field principal stresses. During drilling, the borehole conditions also impact borehole integrity. Factors that we can measure in the borehole during with logging while drilling (LWD) to understand these conditions include mud weight, mud loss, ROP (Rate of Penetration), RPM (Rotation Per Minute), WOB (Weight on Bit), and TORQ (Power swivel torque value). We conducted borehole instability analysis for Site C0002 of the Nankai Trough transect based on riser and riserless drilling during IODP Expedition 338. The borehole shape, determined from LWD resistivity images, indicates that most of drilling occurred in stable environments, however, in a few instances the bottom hole assembly became stuck. We used our stress profile model to evaluate the mud weight required to drill a stable borehole for the estimated rock strength and physical properties. Based on our analysis, we interpret that borehole instability during IODP Expedition 338 may have been caused by weak bedding plane and fluid overpressure state. Future work with this model will investigate the roles of these conditions.

Multiple-Panel Cylindrical Solar Concentrator

NASA Technical Reports Server (NTRS)

Brown, E. M.

1983-01-01

Trough composed of many panels concentrates Sun's energy on solar cells, even when trough is not pointed directly at Sun. Tolerates deviation as great as 5 degrees from direction of sun. For terrestrial applications, multiple-flat-plate design offers potential cost reduction and ease of fabrication.

Assessment of undiscovered continuous oil and gas resources in the Hanoi Trough, Vietnam, 2017

USGS Publications Warehouse

Schenk, Christopher J.; Tennyson, Marilyn E.; Mercier, Tracey J.; Woodall, Cheryl A.; Le, Phuong A.; Klett, Timothy R.; Finn, Thomas M.; Leathers-Miller, Heidi M.; Gaswirth, Stephanie B.; Marra, Kristen R.

2018-02-13

Using a geology-based assessment methodology, the U.S. Geological Survey estimated mean undiscovered, technically recoverable continuous resources of 52 million barrels of oil and 591 billion cubic feet of gas in the Hanoi Trough of Vietnam.

A giant, submarine creep zone as a precursor of large-scale slope instability offshore the Dongsha Islands (South China Sea)

NASA Astrophysics Data System (ADS)

Li, Wei; Alves, Tiago M.; Wu, Shiguo; Rebesco, Michele; Zhao, Fang; Mi, Lijun; Ma, Benjun

2016-10-01

A giant submarine creep zone exceeding 800 km2 on the continental slope offshore the Dongsha Islands, South China Sea, is investigated using bathymetric and 3D seismic data tied to borehole information. The submarine creep zone is identified as a wide area of seafloor undulations with ridges and troughs. The troughs form NW- and WNW-trending elongated depressions separating distinct seafloor ridges, which are parallel or sub-parallel to the continental slope. The troughs are 0.8-4.7 km-long and 0.4 to 2.1 km-wide. The ridges have wavelengths of 1-4 km and vertical relief of 10-30 m. Slope strata are characterised by the presence of vertically stacked ridges and troughs at different stratigraphic depths, but remaining relatively stationary in their position. The interpreted ridges and troughs are associated with large-scale submarine creep, and the troughs can be divided into three types based on their different internal characters and formation processes. The large-scale listric faults trending downslope below MTD 1 and horizon T0 may be the potential glide planes for the submarine creep movement. High sedimentation rates, local fault activity and the frequent earthquakes recorded on the margin are considered as the main factors controlling the formation of this giant submarine creep zone. Our results are important to the understanding of sediment instability on continental slopes as: a) the interpreted submarine creep is young, or even active at present, and b) areas of creeping may evolve into large-scale slope instabilities, as recorded by similar large-scale events in the past.

Geologic evolution of the Kastel trough and its implications on the Adiyaman oil fields, SE Turkey

DOE Office of Scientific and Technical Information (OSTI.GOV)

Coskun, Bu.

1990-05-01

Oil field developments of the Adiyaman area one of the main oil producing zones in southeast Turkey, have been highly influenced by geologic evolution of the Kastel trough which is situated in front of the suture zone between the Arabian and Anatolian plates. The Upper Cretaceous movements created many paleostructural trends in the Kastel trough where important dolomitic and porous reservoirs exist. The most important tectonic event, which appeared during the Upper Cretaceous movements, is the accumulation of the Kocali-Karadut ophiolitic complex, advancing from the north to the south in the Kastel trough, where heavy materials caused formation of amore » structural model favoring generation and migration and entrapment of oil in the reservoir rocks. Due to the presence of the Kocali-Karadut complex in the Kastel trough the following zones have been distinguished. (1) North Uplift Area. Situated under the allochthonous units, many thrust and reverse faults characterize this zone. The presence of paleohighs, where primary dolomites develop, allows the appearance of some oil fields in the region. This is the main future exploration zone in southeast Turkey. (2) Accumulation Area. Advancing from the north to the south, the allochthonous Kocali-Karadut complex filled the Kastel trough creating a deep graben whose flanks present generally normal faults. (3) Structural Belt. Important paleohighs constitute an exploration trend in this zone where dolomitic and porous carbonates contain actual oil fields. (4) South Accumulation Area. Distant from the Arabian-Anatolian suture zone, regional tectonics and sedimentology show this zone remained deeply buried during geologic time; good source rocks were deposited during the Cretaceous. (5) South Uplift Area. This area corresponds to the northern flank of the huge regional Mardin high in southeast Turkey where new oil fields have been discovered.« less

Gas potential of the Rome Trough in Kentucky: Results of recent Cambrian exploration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, D.C.; Drahovzal, J.A.

1996-09-01

A recent gas discovery in the Rome Trough suggests the need to re-evaluate the deep Cambrian potential of eastern Kentucky. A new phase of Cambrian exploration began in mid-1994 with a new pool discovery by the Carson Associates No. 1 Kazee well in Elliott County, Ky. This well blew out and initially flowed 11 MMcfd of gas from the upper Conasauga Group/Rome Formation at 6,258 to 6,270 feet. After this discovery, a second exploratory well (the Blue Ridge No. 1Greene) was drilled on a separate structure in Elliott County in late 1995. The Blue Ridge well was temporarily abandoned, butmore » had shows of gas and condensate. In early 1996, Carson Associates offset their initial discovery well with the No. 33 Lawson Heirs well. This activity follows a frustrating exploration history in the Rome Trough that is marked by numerous gas and oil shows, but rare commercial production. Only three single-well pools have produced commercial gas from the trough, including the recent Kazee well. Stratigraphic units below the Cambrian-Ordovician Knox Group in the Rome Trough are dramatically thicker than their equivalents on the shelf to the north. The interval in the trough is thought to include rocks as old as Early Cambrian, consisting of a basal sandstone, equivalents of the Shady/Tomstown Dolomite, the Rome Formation, and the Conasauga Formation. Sandstones and fractured shales have been responsible for most of the production to date, but dolostone intervals may also have potential. Limited seismic data indicate possible fan-delta and basin-floor fan deposits that may have reservoir potential.« less

Movement of fluids in the Nankai Trough area: Insights from 129I and halogen distributions along the IODP NanTroSEIZE transect

NASA Astrophysics Data System (ADS)

Tomaru, Hitoshi; Fehn, Udo

2015-01-01

Halogen concentrations and 129I/I ratios were determined in pore waters from the Nankai Trough subduction system, collected during IODP Expeditions 315, 316, 322, and 333 along the NanTroSEIZE transect. The transect allowed the first direct comparison of iodine results across an active subduction system, from subducting oceanic sediments to the accretionary prism, and the overlying forearc basin. In contrast to the other halogens (Cl and Br) iodine concentrations show large variations within and among the cores at all sites landward of the trough, I concentrations increase rapidly with depth and reach values several orders of magnitude higher than those in seawater, but are only slightly higher than seawater values at the seaward sites. Methane concentrations follow a similar pattern. Host sediments of the fluids are younger than 7 Ma in all the cores, but the ages of iodine in pore waters at the landward sites reach values beyond 30 Ma. In contrast, iodine seaward of the trough is in isotopic equilibrium with the host sediments, resulting in very similar iodine and sediment ages. The distribution of iodine concentrations and ages indicates that iodine at the landward sites has been transported there in aqueous fluids, probably together with methane, from old formations in the upper plate. The specific fluid pathways potentially were influenced by features such as the megasplay fault in the prism or the décollement. The results demonstrate large-scale transport of fluids carrying iodine and other compounds such as methane from old layers in the upper plate to surface locations landward of the Nankai Trough, while separate, but only local hydrologic processes occur in the marine sediments moving toward the trough.

Structure of the lower crust beneath the Carolina Trough, U.S. Atlantic continental margin

USGS Publications Warehouse

Tréhu, Anne M.; Ballard, A.; Dorman, L.M.; Gettrust, J.F.; Klitgord, Kim D.; Schreiner, A.

1989-01-01

Data from three large-offset seismic profiles provide information on the crustal structure beneath the Carolina trough. The profiles, obtained by the U.S. Geological Survey, the Naval Oceanographic Research Development Agency, and the Scripps Institution of Oceanography in 1985, were oriented parallel to the trough and were located (1) seaward of the East Coast Magnetic Anomaly (ECMA), which is generally thought to represent the boundary between oceanic and continental crust; (2) along the axis of the trough between the ECMA and the hinge zone, which is thought to reflect the landward limit of highly stretched and altered transitional crust; and (3) along the Carolina platform landward of the basement hinge zone on crust thought to have been thinned only slightly during rifting. These data constrain the velocity structure of the lower crust and provide evidence for a thick lens of high-velocity (>7.1 km/s) lower crustal material that extends beneath the Carolina trough and the adjacent ocean basin. This lens reaches a maximum thickness of about 13 km beneath the deepest part of the trough, thins to about 5 km seaward of the ECMA, and is either very thin or absent landward of the hinge zone. It is interpreted to represent material that was underplated beneath and/or intruded into the crust during the late stage of continental rifting and that led to an anomalously thick plutonic layer during the early seafloor spreading phase. These data thus support the recent conclusions of White et al. (1987b) and Mutter et al. (1988) that the initiation of seafloor spreading is attended in many, if not most, cases by the generation of an anomalously large volume of melt.

Top predators in relation to bathymetry, ice and krill during austral winter in Marguerite Bay, Antarctica

USGS Publications Warehouse

Ribic, C.A.; Chapman, E.; Fraser, William R.; Lawson, G.L.; Wiebe, P.H.

2008-01-01

A key hypothesis guiding the US Southern Ocean Global Ocean Ecosystems Dynamics (US SO GLOBEC) program is that deep across-shelf troughs facilitate the transport of warm and nutrient-rich waters onto the continental shelf of the Western Antarctic Peninsula, resulting in enhanced winter production and prey availability to top predators. We tested aspects of this hypothesis during austral winter by assessing the distribution of the resident pack-ice top predators in relation to these deep across-shelf troughs and by investigating associations between top predators and their prey. Surveys were conducted July-August 2001 and August-September 2002 in Marguerite Bay, Antarctica, with a focus on the main across-shelf trough in the bay, Marguerite Trough. The common pack-ice seabird species were snow petrel (Pagodroma nivea, 1.2 individuals km-2), Antarctic petrel (Thalassoica antarctica, 0.3 individuals km-2), and Ade??lie penguin (Pygoscelis adeliae, 0.5 individuals km-2). The most common pack-ice pinniped was crabeater seal (Lobodon carcinophagus). During both winters, snow and Antarctic petrels were associated with low sea-ice concentrations independent of Marguerite Trough, while Ade??lie penguins occurred in association with this trough. Krill concentrations, both shallow and deep, also were associated with Ade??lie penguin and snow petrel distributions. During both winters, crabeater seal occurrence was associated with deep krill concentrations and with regions of lower chlorophyll concentration. The area of lower chlorophyll concentrations occurred in an area with complex bathymetry close to land and heavy ice concentrations. Complex or unusual bathymetry via its influence on physical and biological processes appears to be one of the keys to understanding how top predators survive during the winter in this Antarctic region. ?? 2007 Elsevier Ltd. All rights reserved.

Evaluating the Relationship between Vancomycin Trough Concentration and 24-Hour Area under the Concentration-Time Curve in Neonates.

PubMed

Tseng, Sheng-Hsuan; Lim, Chuan Poh; Chen, Qi; Tang, Cheng Cai; Kong, Sing Teang; Ho, Paul Chi-Lui

2018-04-01

Bacterial sepsis is a major cause of morbidity and mortality in neonates, especially those involving methicillin-resistant Staphylococcus aureus (MRSA). Guidelines by the Infectious Diseases Society of America recommend the vancomycin 24-h area under the concentration-time curve to MIC ratio (AUC 24 /MIC) of >400 as the best predictor of successful treatment against MRSA infections when the MIC is ≤1 mg/liter. The relationship between steady-state vancomycin trough concentrations and AUC 24 values (mg·h/liter) has not been studied in an Asian neonatal population. We conducted a retrospective chart review in Singapore hospitals and collected patient characteristics and therapeutic drug monitoring data from neonates on vancomycin therapy over a 5-year period. A one-compartment population pharmacokinetic model was built from the collected data, internally validated, and then used to assess the relationship between steady-state trough concentrations and AUC 24 A Monte Carlo simulation sensitivity analysis was also conducted. A total of 76 neonates with 429 vancomycin concentrations were included for analysis. Median (interquartile range) was 30 weeks (28 to 36 weeks) for postmenstrual age (PMA) and 1,043 g (811 to 1,919 g) for weight at the initiation of treatment. Vancomycin clearance was predicted by weight, PMA, and serum creatinine. For MRSA isolates with a vancomycin MIC of ≤1, our major finding was that the minimum steady-state trough concentration range predictive of achieving an AUC 24 /MIC of >400 was 8 to 8.9 mg/liter. Steady-state troughs within 15 to 20 mg/liter are unlikely to be necessary to achieve an AUC 24 /MIC of >400, whereas troughs within 10 to 14.9 mg/liter may be more appropriate. Copyright © 2018 American Society for Microbiology.

Spatial patterns of cyanobacterial mat growth on sand ripples

NASA Astrophysics Data System (ADS)

Mariotti, G.; Klepac-Ceraj, V.; Perron, J. T.; Bosak, T.

2016-02-01

Photosynthetic microbial mats produce organic matter, cycle nutrients, bind pollutants and stabilize sediment in sandy marine environments. Here, we investigate the influence of bedforms and wave motion on the growth rate, composition and spatial variability of microbial mats by growing cyanobacterial mats on a rippled bed of carbonate sand in a wave tank. The tank was forced with an oscillatory flow with velocities below the threshold for sediment motion yet able to induce a porewater flow within the sediment. Different spatial patterns developed in mats depending on the initial biochemistry of the water medium. When growing in a medium rich in nitrogen, phosphorous and micronutrients, mats grew faster on ripple troughs than on ripple crests. After two months, mats covered the bed surface uniformly, and the microbial communities on the crests and in the troughs had similar compositions. Differences in bed shear stress and nutrient availability between crests and troughs were not able to explain the faster growth in the troughs. We hypothesize that this growth pattern is due to a "strainer" effect, i.e. the suspended bacteria from the inoculum were preferentially delivered to troughs by the wave-induced porewater flow. In the experiments initiated in a medium previously used up by a microbial mat and thus depleted in nutrients, mats grew preferentially on the ripple crests. This spatial pattern persisted for nearly two years, and the microbial composition on troughs and crests was different. We attribute this pattern to the upwelling of porewater in the crests, which increased the delivery of nutrients from sediment to the cyanobacteria on the bed surface. Thus, the macroscopic patterns formed by photosynthetic microbial mats on sand ripples may be used to infer whether mats are nutrient-limited and whether they are recently colonized or older than a month.

Exposure-response analysis of alectinib in crizotinib-resistant ALK-positive non-small cell lung cancer.

PubMed

Morcos, Peter N; Nueesch, Eveline; Jaminion, Felix; Guerini, Elena; Hsu, Joy C; Bordogna, Walter; Balas, Bogdana; Mercier, Francois

2018-05-10

Alectinib is a selective and potent anaplastic lymphoma kinase (ALK) inhibitor that is active in the central nervous system (CNS). Alectinib demonstrated robust efficacy in a pooled analysis of two single-arm, open-label phase II studies (NP28673, NCT01801111; NP28761, NCT01871805) in crizotinib-resistant ALK-positive non-small-cell lung cancer (NSCLC): median overall survival (OS) 29.1 months (95% confidence interval [CI]: 21.3-39.0) for alectinib 600 mg twice daily (BID). We investigated exposure-response relationships from final pooled phase II OS and safety data to assess alectinib dose selection. A semi-parametric Cox proportional hazards model analyzed relationships between individual median observed steady-state trough concentrations (C trough,ss ) for combined exposure of alectinib and its major metabolite (M4), baseline covariates (demographics and disease characteristics) and OS. Univariate logistic regression analysis analyzed relationships between C trough,ss and incidence of adverse events (AEs: serious and Grade ≥ 3). Overall, 92% of patients (n = 207/225) had C trough,ss data and were included in the analysis. No statistically significant relationship was found between C trough,ss and OS following alectinib treatment. The only baseline covariates that statistically influenced OS were baseline tumor size and prior crizotinib treatment duration. Larger baseline tumor size and shorter prior crizotinib treatment were both associated with shorter OS. Logistic regression confirmed no significant relationship between C trough,ss and AEs. Alectinib 600 mg BID provides systemic exposures at plateau of response for OS while maintaining a well-tolerated safety profile. This analysis confirms alectinib 600 mg BID as the recommended global dose for patients with crizotinib-resistant ALK-positive NSCLC.

Deglacial to Holocene history of ice-sheet retreat and bottom current strength on the western Barents Sea shelf

NASA Astrophysics Data System (ADS)

Lantzsch, Hendrik; Hanebuth, Till J. J.; Horry, Jan; Grave, Marina; Rebesco, Michele; Schwenk, Tilmann

2017-10-01

High-resolution sediment echosounder data combined with radiocarbon-dated sediment cores allowed us to reconstruct the Late Quaternary stratigraphic architecture of the Kveithola Trough and surrounding Spitsbergenbanken. The deposits display the successive deglacial retreat of the Svalbard-Barents Sea Ice Sheet. Basal subglacial till indicates that the grounded ice sheet covered both bank and trough during the Late Weichselian. A glaciomarine blanket inside the trough coinciding with laminated plumites on the bank formed during the initial ice-melting phase from at least 16.1 to 13.5 cal ka BP in close proximity to the ice margin. After the establishment of open-marine conditions at around 13.5 cal ka BP, a sediment drift developed in the confined setting of the Kveithola Trough, contemporary with crudely laminated mud, an overlying lag deposit, and modern bioclastic-rich sand on Spitsbergenbanken. The Kveithola Drift shows a remarkable grain-size coarsening from the moat towards the southern flank of the trough. This trend contradicts the concept of a separated drift (which would imply coarser grain sizes in proximity of the moat) and indicates that the southern bank is the main sediment source for the coarse material building up the Kveithola Drift. This depocenter represents, therefore, a yet undescribed combination of off-bank wedge and confined drift. Although the deposits inside Kveithola Trough and on Spitsbergenbanken display different depocenter geometries, time-equivalent grain-size changes imply a region-wide sediment-dynamic connection. We thus relate a phase of coarsest sediment supply (8.8-6.3 cal ka BP) to an increase in bottom current strength, which might be related to a stronger Atlantic Water inflow from the Southeast across the bank leading to winnowing and off-bank export of sandy sediments.

Sampling procedures for throughfall monitoring: A simulation study

NASA Astrophysics Data System (ADS)

Zimmermann, Beate; Zimmermann, Alexander; Lark, Richard Murray; Elsenbeer, Helmut

2010-01-01

What is the most appropriate sampling scheme to estimate event-based average throughfall? A satisfactory answer to this seemingly simple question has yet to be found, a failure which we attribute to previous efforts' dependence on empirical studies. Here we try to answer this question by simulating stochastic throughfall fields based on parameters for statistical models of large monitoring data sets. We subsequently sampled these fields with different sampling designs and variable sample supports. We evaluated the performance of a particular sampling scheme with respect to the uncertainty of possible estimated means of throughfall volumes. Even for a relative error limit of 20%, an impractically large number of small, funnel-type collectors would be required to estimate mean throughfall, particularly for small events. While stratification of the target area is not superior to simple random sampling, cluster random sampling involves the risk of being less efficient. A larger sample support, e.g., the use of trough-type collectors, considerably reduces the necessary sample sizes and eliminates the sensitivity of the mean to outliers. Since the gain in time associated with the manual handling of troughs versus funnels depends on the local precipitation regime, the employment of automatically recording clusters of long troughs emerges as the most promising sampling scheme. Even so, a relative error of less than 5% appears out of reach for throughfall under heterogeneous canopies. We therefore suspect a considerable uncertainty of input parameters for interception models derived from measured throughfall, in particular, for those requiring data of small throughfall events.

A novel segmentation method for uneven lighting image with noise injection based on non-local spatial information and intuitionistic fuzzy entropy

NASA Astrophysics Data System (ADS)

Yu, Haiyan; Fan, Jiulun

2017-12-01

Local thresholding methods for uneven lighting image segmentation always have the limitations that they are very sensitive to noise injection and that the performance relies largely upon the choice of the initial window size. This paper proposes a novel algorithm for segmenting uneven lighting images with strong noise injection based on non-local spatial information and intuitionistic fuzzy theory. We regard an image as a gray wave in three-dimensional space, which is composed of many peaks and troughs, and these peaks and troughs can divide the image into many local sub-regions in different directions. Our algorithm computes the relative characteristic of each pixel located in the corresponding sub-region based on fuzzy membership function and uses it to replace its absolute characteristic (its gray level) to reduce the influence of uneven light on image segmentation. At the same time, the non-local adaptive spatial constraints of pixels are introduced to avoid noise interference with the search of local sub-regions and the computation of local characteristics. Moreover, edge information is also taken into account to avoid false peak and trough labeling. Finally, a global method based on intuitionistic fuzzy entropy is employed on the wave transformation image to obtain the segmented result. Experiments on several test images show that the proposed method has excellent capability of decreasing the influence of uneven illumination on images and noise injection and behaves more robustly than several classical global and local thresholding methods.

Tsunami Scenarios Based on Interseismic Models Along the Nankai Trough, Japan, From Seafloor and Onshore Geodesy

NASA Astrophysics Data System (ADS)

Watanabe, Shun-ichi; Bock, Yehuda; Melgar, Diego; Tadokoro, Keiichi

2018-03-01

The recent availability of Global Positioning System-Acoustic seafloor geodetic observations enables us to resolve the spatial distribution of the slip deficit rate near the Nankai trough, southwestern Japan. Considering a tectonic block model and the transient deformation due to the major earthquakes in this area, the slip deficit rate between the two relevant blocks can be estimated. In this study, we remove the time-dependent postseismic deformation of the 2004 southeastern off the Kii Peninsula earthquakes (MJMA 7.1, 7.4), which had led to the underestimation of the slip deficit rate in earlier studies. We model the postearthquake viscoelastic relaxation using the 3D finite element model with bi-viscous Burgers rheology, as well as the afterslip on the finite faults. The corrected Global Positioning System-Acoustic and land-based Global Navigation Satellite Systems data are aligned to the existing tectonic model and used to estimate the slip deficit rate on the plate boundary. We then calculate the coseismic displacements and tsunami wave propagation with the simple assumption that a hundred years of constant slip deficit accumulation was released instantaneously. To evaluate the influence of uncertainties in the plate interface geometry on a tsunami model for the Nankai trough, we investigated two different geometries and performed checkerboard inversion simulations. Although the two models indicate roughly similar results, the peak height of the tsunami wave and its arrival time at several points are significantly different in terms of the expected hazard.

Tracking Boulders

NASA Technical Reports Server (NTRS)

2006-01-01

13 March 2006 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows a portion of a trough in the Sirenum Fossae region. On the floor and walls of the trough, large -- truck- to house-sized -- boulders are observed at rest. However, there is evidence in this image for the potential for mobility. In the central portion of the south (bottom) wall, a faint line of depressions extends from near the middle of the wall, down to the rippled trough floor, ending very near one of the many boulders in the area. This line of depressions is a boulder track; it indicates the path followed by the boulder as it trundled downslope and eventually came to rest on the trough floor. Because it is on Mars, even when the boulder is sitting still, this once-rolling stone gathers no moss.

Location near: 29.4oS, 146.6oW Image width: 3 km (1.9 mi) Illumination from: upper left Season: Southern Summer

Near-trench slip potential of megaquakes evaluated from fault properties and conditions

PubMed Central

Hirono, Tetsuro; Tsuda, Kenichi; Tanikawa, Wataru; Ampuero, Jean-Paul; Shibazaki, Bunichiro; Kinoshita, Masataka; Mori, James J.

2016-01-01

Near-trench slip during large megathrust earthquakes (megaquakes) is an important factor in the generation of destructive tsunamis. We proposed a new approach to assessing the near-trench slip potential quantitatively by integrating laboratory-derived properties of fault materials and simulations of fault weakening and rupture propagation. Although the permeability of the sandy Nankai Trough materials are higher than that of the clayey materials from the Japan Trench, dynamic weakening by thermally pressurized fluid is greater at the Nankai Trough owing to higher friction, although initially overpressured fluid at the Nankai Trough restrains the fault weakening. Dynamic rupture simulations reproduced the large slip near the trench observed in the 2011 Tohoku-oki earthquake and predicted the possibility of a large slip of over 30 m for the impending megaquake at the Nankai Trough. Our integrative approach is applicable globally to subduction zones as a novel tool for the prediction of extreme tsunami-producing near-trench slip. PMID:27321861

Microtopographic characterization of ice-wedge polygon landscape in Barrow, Alaska: a digital map of troughs, rims, centers derived from high resolution (0.25 m) LiDAR data

DOE Data Explorer

Gangodagamage, Chandana; Wullschleger, Stan

2014-07-03

The dataset represents microtopographic characterization of the ice-wedge polygon landscape in Barrow, Alaska. Three microtopographic features are delineated using 0.25 m high resolution digital elevation dataset derived from LiDAR. The troughs, rims, and centers are the three categories in this classification scheme. The polygon troughs are the surface expression of the ice-wedges that are in lower elevations than the interior polygon. The elevated shoulders of the polygon interior immediately adjacent to the polygon troughs are the polygon rims for the low center polygons. In case of high center polygons, these features are the topographic highs. In this classification scheme, both topographic highs and rims are considered as polygon rims. The next version of the dataset will include more refined classification scheme including separate classes for rims ad topographic highs. The interior part of the polygon just adjacent to the polygon rims are the polygon centers.

Adalimumab for Treatment of Noninfectious Uveitis: Immunogenicity and Clinical Relevance of Measuring Serum Drug Levels and Antidrug Antibodies.

PubMed

Cordero-Coma, Miguel; Calleja-Antolín, Sara; Garzo-García, Irene; Nuñez-Garnés, Ana M; Álvarez-Castro, Carolina; Franco-Benito, Manuel; Ruiz de Morales, Jose G

2016-12-01

To evaluate the rate of immunogenicity induced by adalimumab and its relationship with drug serum levels and clinical responses in patients with noninfectious uveitis. Prospective observational study. Consecutive patients from 1 referral center who initiated treatment with adalimumab for active noninfectious uveitis resistant to conventional therapy. All patients received 40 mg adalimumab every other week. Patients were evaluated clinically and immunologically before and after 4, 8, and 24 weeks of treatment. Clinical evaluation included assessment of changes in visual acuity, degree of inflammation in the anterior chamber and vitreous cavity, central macular thickness, and retinal angiographic leakage. Immunologic evaluation included assessment of serum trough adalimumab and antibodies against adalimumab (AAA) levels and class II HLA typing. Twenty-five patients were enrolled. Overall, 18 of 25 patients (72%) showed a favorable clinical response to adalimumab therapy. Eleven patients (44%) achieved a complete response and 7 (28%) achieved a partial response. However, 7 of 25 patients (28%) were considered nonresponders. Median trough adalimumab serum levels were higher in responders than in nonresponders (P < 0.001). We observed AAA positivity (AAA+) at least 1 time point in 8 of 25 patients (32%), including 4 with transitory AAA and 4 with permanent AAA. In all patients with permanent AAA+, trough adalimumab levels became undetectable (P < 0.001). However, in patients who demonstrated transitory AAA+, no correlation was observed between AAA titers and adalimumab trough levels (P = 0.2).Concomitant immunosuppression did not show any protective effect on adalimumab immunogenicity in our cohort. An association between the presence of AAA+ and a worse uveitis outcome was observed only in patients with permanent AAA+, which correlated with undetectable adalimumab trough levels (P = 0.014). Treatment of noninfectious uveitis with adalimumab is associated with high rates of favorable clinical response. Overall, adalimumab trough levels were higher in responder patients. Development of permanent AAA was associated with undetectable trough adalimumab levels and worse uveitis outcome. Immunogenicity was more common in patients in whom uveitis was associated with a systemic disease and was not influenced by concomitant immunosuppressors. Copyright © 2016 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

High temperature performance of high-efficiency, multi-layer solar selective coatings for tower applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gray, M. H.; Tirawat, R.; Kessinger, K. A.

The roadmap to next-generation concentrating solar power plants anticipates a progression to central towers with operating temperatures in excess of 650°C. These higher temperatures are required to drive higher power-cycle efficiencies, resulting in lower cost energy. However, these conditions also place a greater burden on the materials making up the receiver. Any novel absorber material developed for next-generation receivers must be stable in air, cost effective, and survive thousands of heating and cooling cycles. The collection efficiency of a power tower plant can be increased if the energy absorbed by the receiver is maximized while the heat loss from themore » receiver to the environment is minimized. Thermal radiation losses can be significant (>7% annual energy loss) with receivers at temperatures above 650°C. We present progress toward highly efficient and durable solar selective absorbers (SSAs) intended for operating temperatures from 650°C to 1000°C. Selective efficiency (η sel) is defined as the energy retained by the absorber, accounting for both absorptance and emittance, relative to the energy incident on the surface. The low emittance layers of multilayer SSAs are binary compounds of refractory metals whose material properties indicate that coatings formed of these materials should be oxidation resistant in air to 800-1200°C. On this basis, we initially developed a solar selective coating for parabolic troughs. This development has been successfully extended to meet the absorptance and emittance objectives for the more demanding, high temperature regime. We show advancement in coating materials, processing and designs resulting in the initial attainment of target efficiencies η sel > 0.91 for proposed tower conditions. Additionally, spectral measurements show that these coatings continue to perform at targeted levels after cycling to temperatures of 1000°C in environments of nitrogen and forming gas.« less

High temperature performance of high-efficiency, multi-layer solar selective coatings for tower applications

DOE PAGES

Gray, M. H.; Tirawat, R.; Kessinger, K. A.; ...

2015-05-01

The roadmap to next-generation concentrating solar power plants anticipates a progression to central towers with operating temperatures in excess of 650°C. These higher temperatures are required to drive higher power-cycle efficiencies, resulting in lower cost energy. However, these conditions also place a greater burden on the materials making up the receiver. Any novel absorber material developed for next-generation receivers must be stable in air, cost effective, and survive thousands of heating and cooling cycles. The collection efficiency of a power tower plant can be increased if the energy absorbed by the receiver is maximized while the heat loss from themore » receiver to the environment is minimized. Thermal radiation losses can be significant (>7% annual energy loss) with receivers at temperatures above 650°C. We present progress toward highly efficient and durable solar selective absorbers (SSAs) intended for operating temperatures from 650°C to 1000°C. Selective efficiency (η sel) is defined as the energy retained by the absorber, accounting for both absorptance and emittance, relative to the energy incident on the surface. The low emittance layers of multilayer SSAs are binary compounds of refractory metals whose material properties indicate that coatings formed of these materials should be oxidation resistant in air to 800-1200°C. On this basis, we initially developed a solar selective coating for parabolic troughs. This development has been successfully extended to meet the absorptance and emittance objectives for the more demanding, high temperature regime. We show advancement in coating materials, processing and designs resulting in the initial attainment of target efficiencies η sel > 0.91 for proposed tower conditions. Additionally, spectral measurements show that these coatings continue to perform at targeted levels after cycling to temperatures of 1000°C in environments of nitrogen and forming gas.« less

A preliminary study of the effects of individual response to challenge tests and stress induced by humans on learning performance of weaned piglets (Sus scrofa).

PubMed

Brajon, Sophie; Laforest, Jean-Paul; Schmitt, Océane; Devillers, Nicolas

2016-08-01

This study investigated whether individual behavioural characteristics of piglets and stress induced by experience with humans can influence learning performance. After weaning, piglets received a chronic experience with humans to modulate their emotional state: rough (ROU), gentle (GEN), or minimal (MIN) experience. Simultaneously, they were trained on a discrimination task. Afterward, their behaviour during challenge tests was assessed. The first learning step of the task involved associating a positive sound cue with a response (approach a trough) and success of piglets depended mostly on motivation to seek for reward. Although the experience with humans did not have direct effect, the degree of fear of handler, measured based on their reactivity to a human approach test, was related to motivation to seek rewards and learning speed of this first step in stressed ROU piglets, but not in MIN and GEN piglets. In contrast, the second learning step was more cognitively challenging, since it involved discrimination learning, including negative cues during which piglets had to learn to avoid the trough. Locomotion activity, measured during an open-field test, was associated with performance of the discrimination learning. To conclude, fearfulness towards humans and locomotion activity are linked with learning performance in relation to task complexity, highlighting the necessity to take into account these factors in animal research and management. Crown Copyright © 2016. Published by Elsevier B.V. All rights reserved.

Preliminary report, cruises L1-86-NC and L2-86-NC, Escanaba Trough, Gorda Ridge

USGS Publications Warehouse

Morton, J.L.; Normark, W.R.; Ross, Stephanie L.; Koski, R.A.; Holmes, M.L.; Shanks, Wayne C.; Zierenberg, R.A.; Lyle, M.W.; Benninger, L.M.

1987-01-01

Eight large (up to 200 m across) and many small massive sulfide deposits were photographed and sampled at the sediment-covered Escanaba Trough, southern Gorda Ridge, during S.P. Lee cruises L1-86-NC and L2-86-NC in 1986. The deposits are associated with two volcanic edifices within the sedimentary fill along the axis of Escanaba Trough. The sulfide and other hydrothermal minerals are deposited on the seafloor as well as within the sedimentary section. High concentrations of Pb and As in some of the sulfide samples indicates significant interaction between hydrothermal fluids and sediment at depth.

Sedimentation, volcanism, and ancestral lakes in the Valles Marineris: Clues from topography

NASA Technical Reports Server (NTRS)

Lucchitta, B. K.; Isbell, N. K.; Howington-Kraus, A.

1993-01-01

Compilation of a simplified geologic/geomorphic map onto a digital terrain model of Valles Marineris has permitted quantitative evaluations of topographic parameters. The study showed that, if their interior layered deposits are lacustrine, the ancestral Valles Marineris must have consisted of isolated basins. If, on the other hand, the troughs were interconnected as they are today, the deposits are most likely to volcanic origin, and the mesas in the peripheral troughs may be table mountains. The material eroded from the trough walls was probably not sufficient to form all of the interior layered deposits, but it may have contributed significantly to their formation.

Performance Evaluation of Dual-axis Tracking System of Parabolic Trough Solar Collector

NASA Astrophysics Data System (ADS)

Ullah, Fahim; Min, Kang

2018-01-01

A parabolic trough solar collector with the concentration ratio of 24 was developed in the College of Engineering; Nanjing Agricultural University, China with the using of the TracePro software an optical model built. Effects of single-axis and dual-axis tracking modes, azimuth and elevating angle tracking errors on the optical performance were investigated and the thermal performance of the solar collector was experimentally measured. The results showed that the optical efficiency of the dual-axis tracking was 0.813% and its year average value was 14.3% and 40.9% higher than that of the eat-west tracking mode and north-south tracking mode respectively. Further, form the results of the experiment, it was concluded that the optical efficiency was affected significantly by the elevation angle tracking errors which should be kept below 0.6o. High optical efficiency could be attained by using dual-tracking mode even though the tracking precision of one axis was degraded. The real-time instantaneous thermal efficiency of the collector reached to 0.775%. In addition, the linearity of the normalized efficiency was favorable. The curve of the calculated thermal efficiency agreed well with the normalized instantaneous efficiency curve derived from the experimental data and the maximum difference between them was 10.3%. This type of solar collector should be applied in middle-scale thermal collection systems.

Project Proposals Evaluation

NASA Astrophysics Data System (ADS)

Encheva, Sylvia; Tumin, Sharil

2009-08-01

Collaboration among various firms has been traditionally used trough single project joint ventures for bonding purposes. Eventhough the performed work is usually beneficial to some extend to all participants, the type of collaboration option to be adapted is strongly influenced by overall purposes and goals that can be achieved. In order to facilitate a choice of collaboration option best suited to a firm's need a computer based model is proposed.

Convection and Easterly Wave Structure Observed in the Eastern Pacific Warm-Pool during EPIC-2001

NASA Technical Reports Server (NTRS)

Peterson, Walter A.; Cifelli, R.; Boccippio, D.; Rutledge, S. A.; Fairall, C. W.; Arnold, James E. (Technical Monitor)

2002-01-01

During September-October 2001, the East Pacific Investigation of Climate Processes in the Coupled Ocean-Atmosphere System (EPIC-2001) ITCZ field campaign focused on studies of deep convection in the warm-pool region of the East Pacific. In addition to the TAO mooring array, observational platforms deployed during the field phase included the NOAA ship RN Ronald H. Brown, the NSF ship RN Horizon, and the NOAA P-3 and NCAR C-130 aircraft. This study combines C-band Doppler radar, rawinsonde, and surface heat flux data collected aboard the RN Brown to describe ITCZ convective structure and rainfall statistics in the eastern Pacific as a function of 3-5 day easterly wave phase. Three distinct easterly wave passages occurred during EPIC-2001. Wind and thermodynamic data reveal that the wave trough axes exhibited positively correlated U and V winds and a slight westward phase tilt with height. A relatively strong (weak) northeasterly deep tropospheric shear followed the trough (ridge) axis. Temperature and humidity perturbations exhibited mid-to upper level cooling (warming) and drying (moistening) in the northerly (trough and southerly) phase. At low levels warming (cooling) occurred in the northerly (southerly) phase with little change in the relative humidity, though mixed layer mixing ratios were larger during the northerly phase. When composited, radar, sounding, lightning and surface heat flux observations suggest the following systematic behavior as a function of wave phase: approximately zero to one quarter wavelength ahead of (behind) the wave trough in northerly (southerly) flow, larger (smaller) CAPE, lower (higher) CIN, weaker (stronger) tropospheric shear, higher (lower) conditional mean rain rates, higher (lower) lightning flash densities, and more (less) robust convective vertical structure occurred. Latent and sensible heat fluxes reached a minimum in the northerly phase and then increased through the trough, reaching a peak during the ridge phase (leading the peak in CAPE). From a radar echo coverage perspective, larger areas of light rain and slightly larger (10%) area averaged rain rates occurred in the vicinity of, and just behind, the trough axes in southerly flow. Importantly, the transition in convective structure observed across the trough axis when considered with the relatively small change in area mean rain rates suggests the presence of a transition in the vertical structure of diabatic heating across the easterly waves examined. The inferred transition in heating structure is supported by radar diagnosed divergence profiles that exhibit convective (stratiform) characteristics ahead of (behind) the trough.

Cycling of sulfur in subduction zones: The geochemistry of sulfur in the Mariana Island Arc and back-arc trough

USGS Publications Warehouse

Alt, J.C.; Shanks, Wayne C.; Jackson, M.C.

1993-01-01

The sulfur contents and sulfur isotopic compositions of 24 glassy submarine volcanics from the Mariana Island Arc and back-arc Mariana Trough were determined in order to investigate the hypothesis that subducted seawater sulfur (??34S = 21???) is recycled through arc volcanism. Our results for sulfur are similar to those for subaerial arc volcanics: Mariana Arc glasses are enriched in 34S (??34S = up to 10.3???, mean = 3.8???) and depleted in S (20-290 ppm, mean = 100 ppm) relative to MORB (850 ppm S, ??34S = 0.1 ?? 0.5???). The back-arc trough basalts contain 200-930 ppm S and have ??34S values of 1.1 ?? 0.5???, which overlap those for the arc and MORB. The low sulfur contents of the arc and some of the trough glasses are attributed to (1) early loss of small amounts of sulfur through separation of immiscible sulfide and (2) later vapor-melt equilibrium control of sulfur contents and loss of sulfur in a vapor phase from sulfide-undersaturated melts near the minimum in sulfur solubility at f{hook}O2 ??? NNO (nickel-nickel oxide). Although these processes removed sulfur from the melts their effects on the sulfur isotopic compositions of the melts were minimal. Positive trends of ??34S with 87Sr 86Sr, LILE and LREE contents of the arc volcanics are consistent with a metasomatic seawater sulfur component in the depleted sub-arc mantle source. The lack of a 34S-rich slab signature in the trough lavas may be attributed to equilibration of metasomatic fluid with mantle material along the longer pathway from the slab to the source of the trough volcanics. Sulfur is likely to have been transported into the mantle wedge by metasomatic fluid derived from subducted sediments and pore fluids. Gases extracted from vesicles in arc and back-arc samples are predominantly H2O, with minor CO2 and traces of H2S and SO2. CO2 in the arc and back-arc rocks has ??13C values of -2.1 to -13.1???, similar to MORB. These data suggest that degassing of CO2 could explain the slightly lower ??13C values for some Mariana Trough volcanic glasses, and that incorporation of subduction-derived organic carbon into the Mariana Trough mantle source may not be necessary. More analyses are required to resolve this question, however. ?? 1993.

Coastal submergence at Ukishima-ga-hara adjacent to the Suruga Trough (eastern Nankai Trough), central Japan, inferred from diatoms and plant macrofossils

NASA Astrophysics Data System (ADS)

Sawai, Y.; Momohara, A.

2017-12-01

Five episodic submergence events during the past 3500 years were recognized at the Ukishima-ga-hara lowland, northern coast of Suruga Trough (eastern Nankai Trough). Coastal submergence in this region was originally reported by Osamu Fujiwara and his colleagues (e.g., Fujiwara et al., 2016) based mainly on changes in lithostratigraphy from a peaty layer that abruptly changed to a light-colored mud and results of microfossil analyses (pollen and diatoms from 57 and 13 samples, respectively). They attributed the submergence events to coseismic deformation associated with earthquakes in the Fujikawa-kako fault zone or Suruga Trough. Here I reevaluated the micropaleontology of this area using 200 samples from 15 cores to reconstruct the full history of coastal submergence during the last few thousand years. The submergence events were shown not by lithostratigraphy but clearly by changes in fossil diatom assemblages and plant macrofossils. For example, at about 2.3 m and 3.1 m below the ground surface, while aerophilic diatoms (such as Diadesmis contenta and Diploneis elliptica) dominate the underlying peaty layer, freshwater and brackish planktonic taxa (Aulacoseira and Thalassiosira) abound in the overlying layer. As many as five such changes in diatom assemblages were found in a 8-m core and radiocarbon ages constrain the age of the entire sequence to 3500 yr BP.

Hydrogeologic Appraisal of the Valley-Fill Aquifer in the Port Jervis Trough, Sullivan and Ulster Counties, New York

USGS Publications Warehouse

Reynolds, Richard J.

2007-01-01

The nature and extent of valley-fill aquifers in the Port Jervis Trough was evaluated for a 16 mile section of this valley from the Orange-Sullivan County line near Westbrookville to the village of Napanoch in Ulster County as part of the U.S. Geological Survey's Detailed Aquifer Mapping Program in New York State. The principal aquifer in the Port Jervis Trough is a 50 feet thick outwash aquifer that extends from the Phillipsport Moraine near Summitville, southward through the study area to Port Jervis, N.Y. Previous studies had estimated as much as 500 feet of saturated drift in parts of the Trough, but new well data show that much of the valley fill consists of fine-grained lacustrine sediments. Drillers' logs show that the outwash aquifer south of Summitville is underlain by as much as 275 feet of lacustrine silt and clay. North of the Phillipsport Moraine, three large glaciolacustrine deltas that were built into Glacial Lake Wawarsing provide some local and discontinuous confined aquifers through their coarser bottomset beds. Elsewhere in the Trough, collapsed and buried portions of kame deltas and terraces provide local confined aquifers. The outwash aquifer appears to be very transmissive, as evidenced by the high specific capacity of 130 gallons per minute per foot [(gal/min)/ft] of a commercial test well screened in the aquifer.

Amplification of drawdown and runup over Hawaii's insular shelves by tsunami N-waves from mega Aleutian earthquakes

NASA Astrophysics Data System (ADS)

Bai, Yefei; Yamazaki, Yoshiki; Cheung, Kwok Fai

2018-04-01

The latest tsunami evacuation maps of Hawaii include an extreme scenario triggered by an Mw 9.3 Aleutian earthquake with large near-trench rupture. The tectonic plate motion produces concentrated seafloor uplift toward the deepest part of the trench generating a tsunami with strong non-hydrostatic characters. A parametric study shows the skewed seafloor uplift produces a dispersive leading crest followed by a prominent trough in the form of an N-wave. The trough maintains its depth across the ocean in the absence of side lobes and dispersion. Shifting of the uplift toward the trench tends to deepen the trough, but has diminishing effects on the wave crest away from the source. While the attenuated leading crest produces relatively moderate runup on north-facing shores of the Hawaiian Islands, with matching of the N-wave and shelf resonance periods, the trough produces an impulsive drawdown followed by an energetic upswing with unprecedented runup for a far-field tsunami. A set of control computations without dispersion reaffirms that a non-hydrostatic model is essential to account for these complex wave processes from the source to the shore. This case study highlights the unique tsunami hazards posed by the Aleutians to Hawaii and the role of wave troughs in delineating the impacts for hazard assessment and engineering design.

Seismic stratigraphic architecture of the Disko Bay trough-mouth fan system, West Greenland

NASA Astrophysics Data System (ADS)

Hofmann, Julia C.; Knutz, Paul C.

2015-04-01

Spatial and temporal changes of the Greenland Ice Sheet on the continental shelf bordering Baffin Bay remain poorly constrained. Then as now, fast-flowing ice streams and outlet glaciers have played a key role for the mass balance and stability of polar ice sheets. Despite their significance for Greenland Ice Sheet dynamics and evolution, our understanding of their long-term behaviour is limited. The central West Greenland margin is characterized by a broad continental shelf where a series of troughs extend from fjords to the shelf margin, acting as focal points for trough-mouth fan (TMF) accummulations. The sea-ward bulging morphology and abrupt shelf-break of these major depositional systems is generated by prograding depocentres that formed during glacial maxima when ice streams reached the shelf edge, delivering large amounts of subglacial sediment onto the continental slope (Ó Cofaigh et al., 2013). The aim of this study is to unravel the seismic stratigraphic architecture and depositional processes of the Disko Bay TMF, aerially the largest single sedimentary system in West Greenland, using 2D and 3D seismic reflection data, seabed bathymetry and stratigraphic information from exploration well Hellefisk-1. The south-west Disko Bay is intersected by a deep, narrow trough, Egedesminde Dyb, which extends towards the southwest and links to the shallower and broader cross-shelf Disko Trough (maximum water depths of > 1000 m and a trough length of c. 370 km). Another trough-like depression (trough length of c. 120 km) in the northern part of the TMF, indicating a previous position of the ice stream, can be distinguished on the seabed topographic map and the seismic images. The Disko Bay TMF itself extends from the shelf edge down to the abyssal plain (abyssal floor depths of 2000 m) of the southern Baffin Bay. Based on seismic stratigraphic configurations relating to reflection terminations, erosive patterns and seismic facies (Mitchum et al., 1977), the TMF succession has been divided into five seismic units, each representing different stages in the progradational accumulation of the TMF system. This poster and ongoing study will discuss how the ice-stream flow switching is linked to changes in depocentres of sedimentary sequences and further investigate the major controls, e.g. ice-sheet dynamics, ocean-climate changes, tectonic forcing and subglacial geology, that determined the evolution of the Disko Bay TMF. Essencial bibliography Mitchum, R.M. Jr., Vail, P.R., Sangree, J.B., 1977. Seismic stratigraphy and global changes of sea level, Part 6: Stratigraphic interpretation of seismic reflection patterns in depositional sequences. AAPG Memoir 26, 117-133. Ó Cofaigh, C., Andrews, J.T., Jennings, A.E., Dowdeswell, J.A., Hogan, K.A., Kilfeather, A.A., Sheldon, C., 2013. Glacimarine lithofacies, provenance and depositional processes on a West Greenland trough-mouth fan. Journal of Quaternary Science, 28(1), 13-26.

Recognition and characterization of networks of water bodies in the Arctic ice-wedge polygonal tundra using high-resolution satellite imagery

NASA Astrophysics Data System (ADS)

Skurikhin, A. N.; Gangodagamage, C.; Rowland, J. C.; Wilson, C. J.

2013-12-01

Arctic lowland landscapes underlain by permafrost are often characterized by polygon-like patterns such as ice-wedge polygons outlined by networks of ice wedges and complemented with polygon rims, troughs, shallow ponds and thermokarst lakes. Polygonal patterns and corresponding features are relatively easy to recognize in high spatial resolution satellite imagery by a human, but their automated recognition is challenging due to the variability in their spectral appearance, the irregularity of individual trough spacing and orientation within the patterns, and a lack of unique spectral response attributable to troughs with widths commonly between 1 m and 2 m. Accurate identification of fine scale elements of ice-wedge polygonal tundra is important as their imprecise recognition may bias estimates of water, heat and carbon fluxes in large-scale climate models. Our focus is on the problem of identification of Arctic polygonal tundra fine-scale landscape elements (as small as 1 m - 2 m width). The challenge of the considered problem is that while large water bodies (e.g. lakes and rivers) can be recognized based on spectral response, reliable recognition of troughs is more difficult. Troughs do not have unique spectral signature, their appearance is noisy (edges are not strong), their width is small, and they often form connected networks with ponds and lakes, and thus they have overlapping spectral response with other water bodies and surrounding non-water bodies. We present a semi-automated approach to identify and classify Arctic polygonal tundra landscape components across the range of spatial scales, such as troughs, ponds, river- and lake-like objects, using high spatial resolution satellite imagery. The novelty of the approach lies in: (1) the combined use of segmentation and shape-based classification to identify a broad range of water bodies, including troughs, and (2) the use of high-resolution WorldView-2 satellite imagery (with resolution of 0.6 m) for this identification. The approach starts by segmenting water bodies from an image, which are then categorized using shape-based classification. Segmentation uses combination of pan sharpened multispectral bands and is based on the active contours without edges technique. The segmentation is robust to noise and can detect objects with weak boundaries that is important for extraction of troughs. We then categorize the segmented regions via shape based classification. Because segmentation accuracy is the main factor impacting the quality of the shape-based classification, for segmentation accuracy assessment we created reference image using WorldView-2 satellite image of ice-wedge polygonal tundra. Reference image contained manually labelled image regions which cover components of drainage networks, such as troughs, ponds, rivers and lakes. The evaluation has shown that the approach provides a good accuracy of segmentation and reasonable classification results. The overall accuracy of the segmentation is approximately 95%, the segmentation user's and producer's accuracies are approximately 92% and 97% respectively.

Last deglaciation of the Svalbard/Barents Sea Ice Sheet - a swath bathymetric and sub-bottom seismic study from the Kveithola Trough

NASA Astrophysics Data System (ADS)

Rebesco, Michele; Liu, Yanguang; Camerlenghi, Angelo; Winsborrow, Monica; Sverre Laberg, Jan; Caburlotto, Andrea; Diviacco, Paolo; Accettella, Daniela; Sauli, Chiara; Wardell, Nigel

2010-05-01

Kveithola Trough, an E-W trending cross-shelf glacial trough in the NW Barents Sea, was surveyed for the first time during the EGLACOM cruise between 8th July and 4th August 2008 on board R/V OGS-Explora. EGLACOM (Evolution of a GLacial Arctic COntinental Margin: the southern Svalbard ice stream-dominated sedimentary system) project is the Italian contribution to the International Polar Year (IPY) Activity 367 (Neogene ice streams and sedimentary processes on high- latitude continental margins - NICE STREAMS). Such IPY activity included as well the Spanish SVAIS 2008 cruise on board BIO Hesperides. EGLACOM data acquisition, focused on the Storfjorden Fan and Kveithola Trough, included a multi-channel seismic (MCS) reflection survey and the simultaneous collection of swath bathymetry and sub-bottom CHIRP profiles. Swath bathymetry in the Kveithola Trough shows that the seafloor is characterized by E-W trending mega-scale glacial lineations (MSGL). These include large-scale ridges about 2 km wide and 15 m high as well as smaller grooves about 100 m wide and a few metres deep. Such MSGL record the fast flow of an ice stream draining the Svalbard/Barents Sea Ice Sheet (SBSIS) during the Last Glacial Maximum (LGM). MSGL are overprinted by transverse sediment ridges about 15 km apart which give rise to a staircase long profile of the trough. Such transverse ridges are interpreted as grounding-zone wedges (GZW) formed by deposition of unconsolidated, saturated subglacial till during ice stream retreat. Sub-bottom (CHIRP) and multi-channel reflection seismic data show that the morphology is controlled by stacked sets of lensoidal transparent units (tills) overlain by a draping glaciomarine unit up to over 15 m thick. Formed during temporary stillstands in grounding-zone position before complete deglaciation, GZW ridges are diagnostic of episodic retreat. Our data allow the reconstruction of deglaciation in the Spitsbergen Bank area, with each stage during deglaciation recorded by deposition of a GZW. Three independent lines of reasoning suggest that an ice cap persisted on Spitsbergen Bank for some thousand years and lasted much longer than those that fed the adjacent glacial troughs: 1) the freshness of the morphology in Kveithola Trough compared to that of adjacent Storfjorden and Bear Island troughs; 2) the volume of sediment in the GZW ridges compared to the small catchment area; 3) preliminary assessment of the stratigraphic position of debris flow deposits on the continental slope. The 15 m of sedimentary drape deposited on top of GZW ridges contains a high-resolution palaeoclimatic record of the last thousand years, which accumulated at a very high average sedimentation rate. Sampling (through drilling) of the thin glaciomarine sediments between the till lenses of the successive GZW ridges may allow the dating of deglaciation phases in the Barents Sea.

Extended-interval Dosing of Gentamicin in Premature Neonates Born at <32 Weeks' Gestation and >7 Days of age.

PubMed

Sundaram, Arun; Alshaikh, Belal; Dersch-Mills, Deonne; Dobry, Jenna; Akierman, Albert R; Yusuf, Kamran

2017-06-01

Extended-interval dosing (EID) regimens of gentamicin have been validated for treating confirmed or suspected early- and late-onset sepsis in preterm infants in the first week of life. Despite the marked changes in volume of distribution and renal clearance in preterm infants after the first few days of life, few studies have validated EID regimens of gentamicin in this population. The objective of the study was to evaluate an EID regimen of gentamicin in infants born at <32 weeks' gestational age and aged >7 days. This observational study of an EID regimen was conducted in 39 infants. Dosing interval was based on the serum drug concentration at 22 hours after the administration of the first dose of 5 mg/kg. Gentamicin peak (5-12 µg/mL) and trough (<2 µg/mL) levels were compared to those in a historical control group of 39 infants who received traditional-interval dosing (TID) of 2.5 mg/kg of gentamicin with dosing intervals of 8, 12, or 24 hours. There were no differences in birthweight, gestational age at birth, postmenstrual age, weight at the start of gentamicin administration, postnatal age, small for gestational age status, antenatal corticosteroid use, or postnatal indomethacin exposure between the 2 groups. In the EID group, dosing intervals were 24 hours in 30 infants, 36 hours in 6 infants, and 48 hours in 3 infants. Compared with the TID group (n = 39), the EID group had a significantly higher peak level (median, 9.0 vs 4.7 µg/mL) and a significantly lower trough level (median, 0.7 vs 1.1 µg/mL) (both, P < 0.001). On regression analysis, the postmenstrual age was correlated significantly with trough levels in the EID group. There was no adverse effect on renal function in either group. On follow-up, 1 infant in the EID group and 2 infants in the TID group had evidence of sensorineural hearing loss. In infants born at <32 weeks' gestation and >7 days of age, an EID gentamicin regimen, with a dosing interval based on a single concentration measurement at 22 hours after the administration of the first dose, achieved therapeutic peak and trough levels and performed significantly better than did a TID regimen in reaching target peak and trough levels. Larger-scale trials are needed for assessing the clinical efficacy (treatment failure/success) of these regimens. Copyright © 2017 Elsevier HS Journals, Inc. All rights reserved.

Aerial mulching techniques-trough fire

Treesearch

Robert Faust

2008-01-01

The Trough fire occurred in August 2001 on the Mendocino National Forest of northern California. A burned area emergency rehabilitation team evaluated the fire effects on the watershed. Concerns were soil from the denuded slopes moving into streams affecting fishery values, reservoir sedimentation and storm runoff plugging culverts leading to road wash outs. Past...

Strawberry Production in Soilless Substrate Troughs – Plant Growth

USDA-ARS?s Scientific Manuscript database

Soilless substrates made of peat moss, coconut coir, perlite, rockwool or bark are pathogen free and they have been used in strawberry production in Europe in troughs or containers. Open field strawberry production in soilless substrate is new to California growers. The objective of this study was t...

Effects of Combination Therapy With Immunomodulators on Trough Levels and Antibodies Against Tumor Necrosis Factor Antagonists in Patients With Inflammatory Bowel Disease: A Meta-analysis.

PubMed

Qiu, Yun; Mao, Ren; Chen, Bai-Li; Zhang, Sheng-Hong; Guo, Jing; He, Yao; Zeng, Zhi-Rong; Ben-Horin, Shomron; Chen, Min-Hu

2017-09-01

It is not clear whether combination therapy with immunomodulators affects the immunogenicity of tumor necrosis factor (TNF) antagonists in patients with inflammatory bowel disease. We performed a meta-analysis to quantify the effects of combined immunomodulator therapy on the presence of antibodies against TNF antagonists (antidrug antibodies [ADAs]) and trough levels of anti-TNF agents. We systematically searched publication databases for studies that reported prevalence of ADAs in patients who received anti-TNF agents. Raw data from studies that met the inclusion criteria were pooled to determine effect estimates. We performed subgroup and metaregression analyses to determine the level of heterogeneity among study outcomes. We analyzed findings from 35 studies that met inclusion criteria (results reported from 6790 patients with inflammatory bowel disease). The pooled risk ratio for formation of ADAs in patients receiving combined therapy with immunomodulators, versus that of patients receiving anti-TNF monotherapy, was 0.49 (95% confidence interval, 0.41-0.59; P < .001). However, the pooled analysis did not demonstrate a significant difference in trough levels of anti-TNF agents between patients with versus without concurrent use of immunomodulators (standardized mean difference, 0.11; 95% confidence interval, 0.19-0.41; P = .47). Subgroup analyses of patients treated with different TNF antagonists revealed no difference in the formation of ADAs (P = .50 for interaction); the protective effect of immunomodulators did not differ with type of drug patients were given (methotrexate vs thiopurines), or assay for ADA. We observed heterogeneity only among studies of patients with ulcerative colitis (I 2  = 76%). Funnel plot and Egger test analyses indicated publication bias in the studies (P = .001). In a meta-analysis of published studies, we associated combined treatment with immunomodulators with reduced risk of formation of antibodies against TNF antagonists in patients with inflammatory bowel disease. Copyright © 2017 AGA Institute. Published by Elsevier Inc. All rights reserved.

Geohydrology of the stratified-drift aquifer system in the lower Sixmile Creek and Willseyville Creek trough, Tompkins County, New York

USGS Publications Warehouse

Miller, Todd S.; Karig, Daniel E.

2010-01-01

In 2002, the U.S. Geological Survey, in cooperation with the Tompkins County Planning Department began a series of studies of the stratified-drift aquifers in Tompkins County to provide geohydrologic data for planners to develop a strategy to manage and protect their water resources. This aquifer study in lower Sixmile Creek and Willseyville Creek trough is the second in a series of aquifer studies in Tompkins County. The study area is within the northern area of the Appalachian Plateau and extends about 9 miles from the boundary between Tompkins County and Tioga County in the south to just south of the City of Ithaca in the north. In lower Sixmile Creek and Willseyville Creek trough, confined sand and gravel aquifers comprise the major water-bearing units while less extensive unconfined units form minor aquifers. About 600 people who live in lower Sixmile Creek and Willseyville Creek trough rely on groundwater from the stratified-drift aquifer system. In addition, water is used by non-permanent residents such as staff at commercial facilities. The estimated total groundwater withdrawn for domestic use is about 45,000 gallons per day (gal/d) or 0.07 cubic foot per second (ft3/s) based on an average water use of 75 gal/d per person for self-supplied water systems in New York. Scouring of bedrock in the preglacial lower Sixmile Creek and Willseyville Creek valleys by glaciers and subglacial meltwaters truncated hillside spurs, formed U-shaped, transverse valley profiles, smoothed valley walls, and deepened the valleys by as much as 300 feet (ft), forming a continuous trough. The unconsolidated deposits in the study area consist mostly of glacial drift, both unstratified drift (till) and stratified drift (laminated lake, deltaic, and glaciofluvial sediments), as well as some post-glacial stratified sediments (lake-bottom sediments that were deposited in reservoirs, peat and muck that were deposited in wetlands, and alluvium deposited by streams). Multiple advances and retreats of the ice in the study area resulted in several sequences of various types of glacial deposits. A large moraine (Valley Heads Moraine) dominates the southern part of the study area, a large delta dominates the central part, and ground moraine (mostly till) dominates the northern part. Glacial sediments in the center of the lower Sixmile Creek and Willseyville Creek trough typically range from 150 to 200 ft but can be greater than 300 ft in some places. Where the sediments are composed of sand and gravel they form aquifers. In most parts of the lower Sixmile Creek and Willseyville Creek trough, there is an upper and a basal confined aquifer. However, underlying the central parts of the Brooktondale delta, there are as many as four confined aquifers, whereas in the northern part of the study area, only one extensive confined aquifer is present. The major sources of recharge to these confined aquifers are (1) direct infiltration of precipitation where confined aquifers crop out at land surface (mostly along the western trough wall in the southern and central parts of the study area and, to a lesser degree, along the eastern trough wall); (2) unchanneled surface and subsurface runoff from adjacent upland areas that seeps into the aquifer along the western trough walls; (3) subsurface flow from underlying till or bedrock at the lateral contacts at trough walls; (4) adjacent fine-grained stratified drift, especially when the aquifer is pumped; and (5) discharge from bedrock at the bottom and sides of the trough. In the central part of the study area, the surficial coarse-grained sediments (sand and gravel) comprise a delta near Brooktondale and form a small unconfined aquifer (0.3 square mile). Although much of the upper part of the delta has been removed by several aggregate mining operations, sufficient amounts of sand and gravel remain in most places to form a thin unconfined aquifer. The major sources of recharge to the unconfined aquifer are (1)

Control Chart on Semi Analytical Weighting

NASA Astrophysics Data System (ADS)

Miranda, G. S.; Oliveira, C. C.; Silva, T. B. S. C.; Stellato, T. B.; Monteiro, L. R.; Marques, J. R.; Faustino, M. G.; Soares, S. M. V.; Ulrich, J. C.; Pires, M. A. F.; Cotrim, M. E. B.

2018-03-01

Semi-analytical balance verification intends to assess the balance performance using graphs that illustrate measurement dispersion, trough time, and to demonstrate measurements were performed in a reliable manner. This study presents internal quality control of a semi-analytical balance (GEHAKA BG400) using control charts. From 2013 to 2016, 2 weight standards were monitored before any balance operation. This work intended to evaluate if any significant difference or bias were presented on weighting procedure over time, to check the generated data reliability. This work also exemplifies how control intervals are established.

Improvements in the simulation code of the SOX experiment

NASA Astrophysics Data System (ADS)

Caminata, A.; Agostini, M.; Altenmüeller, K.; Appel, S.; Atroshchenko, V.; Bellini, G.; Benziger, J.; Bick, D.; Bonfini, G.; Bravo, D.; Caccianiga, B.; Calaprice, F.; Carlini, M.; Cavalcante, P.; Chepurnov, A.; Choi, K.; Cribier, M.; D'Angelo, D.; Davini, S.; Derbin, A.; Di Noto, L.; Drachnev, I.; Durero, M.; Etenko, A.; Farinon, S.; Fischer, V.; Fomenko, K.; Franco, D.; Gabriele, F.; Gaffiot, J.; Galbiati, C.; Gschwender, M.; Ghiano, C.; Giammarchi, M.; Goeger-Neff, M.; Goretti, A.; Gromov, M.; Hagner, C.; Houdy, Th.; Hungerford, E.; Ianni, Aldo; Ianni, Andrea; Jonquères, N.; Jany, A.; Jedrzejczak, K.; Jeschke, D.; Kobychev, V.; Korablev, D.; Korga, G.; Kornoukhov, V.; Kryn, D.; Lachenmaier, T.; Lasserre, T.; Laubenstein, M.; Lehnert, B.; Link, J.; Litvinovich, E.; Lombardi, F.; Lombardi, P.; Ludhova, L.; Lukyanchenko, G.; Machulin, I.; Manecki, S.; Maneschg, W.; Manuzio, G.; Marcocci, S.; Maricic, J.; Mention, G.; Meroni, E.; Meyer, M.; Miramonti, L.; Misiaszek, M.; Montuschi, M.; Mosteiro, P.; Muratova, V.; Musenich, R.; Neumair, B.; Oberauer, L.; Obolensky, M.; Ortica, F.; Pallavicini, M.; Papp, L.; Pocar, A.; Ranucci, G.; Razeto, A.; Re, A.; Romani, A.; Roncin, R.; Rossi, N.; Schönert, S.; Scola, L.; Semenov, D.; Skorokhvatov, M.; Smirnov, O.; Sotnikov, A.; Sukhotin, S.; Suvorov, Y.; Tartaglia, R.; Testera, G.; Thurn, J.; Toropova, M.; Unzhakov, E.; Veyssiére, C.; Vishneva, A.; Vivier, M.; Vogelaar, R. B.; von Feilitzsch, F.; Wang, H.; Weinz, S.; Winter, J.; Wojcik, M.; Wurm, M.; Yokley, Z.; Zaimidoroga, O.; Zavatarelli, S.; Zuber, K.; Zuzel, G.

2017-09-01

The aim of the SOX experiment is to test the hypothesis of existence of light sterile neutrinos trough a short baseline experiment. Electron antineutrinos will be produced by an high activity source and detected in the Borexino experiment. Both an oscillometry approach and a conventional disappearance analysis will be performed and, if combined, SOX will be able to investigate most of the anomaly region at 95% c.l. This paper focuses on the improvements performed on the simulation code and on the techniques (calibrations) used to validate the results.

Charging machine

DOEpatents

Medlin, John B.

1976-05-25

A charging machine for loading fuel slugs into the process tubes of a nuclear reactor includes a tubular housing connected to the process tube, a charging trough connected to the other end of the tubular housing, a device for loading the charging trough with a group of fuel slugs, means for equalizing the coolant pressure in the charging trough with the pressure in the process tubes, means for pushing the group of fuel slugs into the process tube and a latch and a seal engaging the last object in the group of fuel slugs to prevent the fuel slugs from being ejected from the process tube when the pusher is removed and to prevent pressure liquid from entering the charging machine.

Peak Measurement for Vancomycin AUC Estimation in Obese Adults Improves Precision and Lowers Bias.

PubMed

Pai, Manjunath P; Hong, Joseph; Krop, Lynne

2017-04-01

Vancomycin area under the curve (AUC) estimates may be skewed in obese adults due to weight-dependent pharmacokinetic parameters. We demonstrate that peak and trough measurements reduce bias and improve the precision of vancomycin AUC estimates in obese adults ( n = 75) and validate this in an independent cohort ( n = 31). The precision and mean percent bias of Bayesian vancomycin AUC estimates are comparable between covariate-dependent ( R 2 = 0.774, 3.55%) and covariate-independent ( R 2 = 0.804, 3.28%) models when peaks and troughs are measured but not when measurements are restricted to troughs only ( R 2 = 0.557, 15.5%). Copyright © 2017 American Society for Microbiology.

Variations of the ionospheric plasma concentration in the region of the main ionospheric trough during the magnetic storm of December 18-19, 1978, in connection with measurements of the interplanetary magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gdalevich, G.L.; Afonin, V.V.; Eliseev, A.Y.

1986-07-01

Data from the Kosmos-900 satellite are used to examine variations of the ion concentration in the region of the main ionospheric trough at altitudes of about 500 km during the storm of December 18-19, 1978. These variations of ion densities are compared with the variations of the parameters of the interplanetary medium, in particular, with the E /sub y/ = -VB /sub z/ component of the interplanetary electric field. The results of the comparison are discussed. A scheme is proposed for the formation and motion of the trough during magnetic disturbances.

System Dynamic Model for the Accumulation of Renewable Electricity using Power-to-Gas and Power-to-Liquid Concepts

NASA Astrophysics Data System (ADS)

Blumberga, Andra; Timma, Lelde; Blumberga, Dagnija

2015-12-01

When the renewable energy is used, the challenge is match the supply of intermittent energy with the demand for energy therefore the energy storage solutions should be used. This paper is dedicated to hydrogen accumulation from wind sources. The case study investigates the conceptual system that uses intermitted renewable energy resources to produce hydrogen (power-to-gas concept) and fuel (power-to-liquid concept). For this specific case study hydrogen is produced from surplus electricity generated by wind power plant trough electrolysis process and fuel is obtained by upgrading biogas to biomethane using hydrogen. System dynamic model is created for this conceptual system. The developed system dynamics model has been used to simulate 2 different scenarios. The results show that in both scenarios the point at which the all electricity needs of Latvia are covered is obtained. Moreover, the methodology of system dynamics used in this paper is white-box model that allows to apply the developed model to other case studies and/or to modify model based on the newest data. The developed model can be used for both scientific research and policy makers to better understand the dynamic relation within the system and the response of system to changes in both internal and external factors.

Visual and Auditory Sensitivities and Discriminations

DTIC Science & Technology

2003-03-03

Experimental Psychology : Human Perception and Performance, 26, 1721-1723. The data have also been reported to ECVP at the Trieste meeting, and to the Edinburgh...design to measure the disparity required to just detect the cyclopean test bars (Macmillan & Creelman , 1991). Each trial consisted of a single...conventionally (Macmillan & Creelman , 1991). Results Grating detection threshold (d =1.0) for observer 1 was estimated as 0.18 arc min peak-to-trough

Continuous depth profile of the rock strength in the Nankai accretionary prism based on drilling performance parameters.

PubMed

Hamada, Yohei; Kitamura, Manami; Yamada, Yasuhiro; Sanada, Yoshinori; Sugihara, Takamitsu; Saito, Saneatsu; Moe, Kyaw; Hirose, Takehiro

2018-02-14

A new method for evaluating the in situ rock strength beneath the seafloor is proposed and applied to the Nankai Trough accretionary prism. The depth-continuous in situ rock strength is a critical parameter for numerous studies in earth science, particularly for seismology and tectonics at plate convergence zones; yet, measurements are limited owing to a lack of drilled cores. Here, we propose a new indicator of strength, the equivalent strength (EST), which is determined only by drilling performance parameters such as drill string rotational torque, bit depth, and string rotational speed. A continuous depth profile of EST was drawn from 0 to 3000 m below the seafloor (mbsf) across the forearc basin and accretionary prism in the Nankai Trough. The EST did not show a significant increase around the forearc basin-accretionary prism boundary, but it did show a clear increase within the prism, ca. below 1500 mbsf. This result may indicate that even the shallow accretionary prism has been strengthened by horizontal compression derived from plate subduction. The EST is a potential parameter to continuously evaluate the in situ rock strength during drilling, and its accuracy of the absolute value can be improved by combining with laboratory drilling experiments.

Two-stage solar concentrators based on parabolic troughs: asymmetric versus symmetric designs.

PubMed

Schmitz, Max; Cooper, Thomas; Ambrosetti, Gianluca; Steinfeld, Aldo

2015-11-20

While nonimaging concentrators can approach the thermodynamic limit of concentration, they generally suffer from poor compactness when designed for small acceptance angles, e.g., to capture direct solar irradiation. Symmetric two-stage systems utilizing an image-forming primary parabolic concentrator in tandem with a nonimaging secondary concentrator partially overcome this compactness problem, but their achievable concentration ratio is ultimately limited by the central obstruction caused by the secondary. Significant improvements can be realized by two-stage systems having asymmetric cross-sections, particularly for 2D line-focus trough designs. We therefore present a detailed analysis of two-stage line-focus asymmetric concentrators for flat receiver geometries and compare them to their symmetric counterparts. Exemplary designs are examined in terms of the key optical performance metrics, namely, geometric concentration ratio, acceptance angle, concentration-acceptance product, aspect ratio, active area fraction, and average number of reflections. Notably, we show that asymmetric designs can achieve significantly higher overall concentrations and are always more compact than symmetric systems designed for the same concentration ratio. Using this analysis as a basis, we develop novel asymmetric designs, including two-wing and nested configurations, which surpass the optical performance of two-mirror aplanats and are comparable with the best reported 2D simultaneous multiple surface designs for both hollow and dielectric-filled secondaries.

Design of a Field Raised-Bed Trough System using Soilless Substrates for Strawberry Production in California

USDA-ARS?s Scientific Manuscript database

There are a number of approaches for producing strawberry fruit on a commercial scale without fumigants. One possible approach is to grow strawberries using raised-bed troughs filled with non soil based substrate media. Field trials were conducted using peat, perlite, coir, rice hull, and a redwoo...

Small mammals in oak woodlands in the Puget Trough, Washington.

Treesearch

S.M. Wilson; A.B. Carey

2001-01-01

We surveyed the 22 largest sites dominated by Oregon white oaks on the Fort Lewis Military Reservation, Washington, to determine small-mammal community structure and population abundances. Study areas were in the Puget Trough physiographic province and western hemlock vegetation zone. Most oak communities were ecotonal between prairie and Douglas-fir forest. Small...

--No Title--

Science.gov Websites

SOUTHERN ROCKIES... A BROAD LONG WAVE TROUGH CROSSES THE CENTRAL AND SOUTHERN ROCKIES DURING DAY 1...BEFORE WEAKENING AND EXITING INTO THE PLAINS DURING DAY 2. SURFACE LOW PRESSURE FORMING IN RESPONSE TO THE MID MOST RECENT WPC QPF. DAY 1... LIFT ASSOCIATED WITH A BROAD POSITIVELY TILTED LONG WAVE TROUGH MOVING

SeaMARC II mapping of transform faults in the Cayman Trough, Caribbean Sea

USGS Publications Warehouse

Rosencrantz, Eric; Mann, Paul

1992-01-01

SeaMARC II maps of the southern wall of the Cayman Trough between Honduras and Jamaica show zones of continuous, well-defined fault lineaments adjacent and parallel to the wall, both to the east and west of the Cayman spreading axis. These lineaments mark the present, active traces of transform faults which intersect the southern end of the spreading axis at a triple junction. The Swan Islands transform fault to the west is dominated by two major lineaments that overlap with right-stepping sense across a large push-up ridge beneath the Swan Islands. The fault zone to the east of the axis, named the Walton fault, is more complex, containing multiple fault strands and a large pull-apart structure. The Walton fault links the spreading axis to Jamaican and Hispaniolan strike-slip faults, and it defines the southern boundary of a microplate composed of the eastern Cayman Trough and western Hispaniola. The presence of this microplate raises questions about the veracity of Caribbean plate velocities based primarily on Cayman Trough opening rates.

Ionospheric and magnetospheric plasmapauses'

NASA Technical Reports Server (NTRS)

Grebowsky, J. M.; Hoffman, J. H.; Maynard, N. C.

1977-01-01

During August 1972, Explorer 45 orbiting near the equatorial plane with an apogee of about 5.2 R sub e traversed magnetic field lines in close proximity to those simultaneously traversed by the topside ionospheric satellite ISIS 2 near dusk in the L range 2-5.4. The locations of the Explorer 45 plasmapause crossings during this month were compared to the latitudinal decreases of the H(+) density observed on ISIS 2 near the same magnetic field lines. The equatorially determined plasmapause field lines typically passed through or poleward of the minimum of the ionospheric light ion trough, with coincident satellite passes occurring for which the L separation between the plasmapause and trough field lines was between 1 and 2. Vertical flows of the H(+) ions in the light ion trough as detected by the magnetic ion mass spectrometer on ISIS were directed upward with velocities between 1 and 2 kilometers/sec near dusk on these passes. These velocities decreased to lower values on the low latitude side of the H(+) trough but did not show any noticeable change across the field lines corresponding to the magnetospheric plasmapause.

A survey of major east coast snowstorms, 1960-1983. Part 2. Summary of surface and upperlevel characteristics

NASA Technical Reports Server (NTRS)

Kocin, P. J.; Uccellini, L. W.

1985-01-01

Surface and upper-level characteristics of selected meteorological fields are summarized. Two major types of sea level development are described and applied to the cases at hand, with a few storm systems showing characteristics of both types. Aspects such as rapid sea level deepening, coastal frontogenesis, cold air damming, low level jet formation, the development of an S-shaped isotherm pattern, diffluence downwind of a negatively tilted upper level trough axis, upper level confluence and an increase of geopotential heights at the base of the upper level trough characterized the pre-cyclogenetic and cyclogenetic periods of many of the storm systems. Large variability was also observed, especially with regard to the spatial dimensions of the surface and upper level systems, as well as variations in trough/ridge amplification and the evolution of upper level jet streak systems. The influence of transverse circulations associated with a confluent jet streak entrance region and the diffluent exit region of a jet streak/trough system on the production of snowfall is also discussed.

Far-Field Noise Induced by Bubble near Free Surface

NASA Astrophysics Data System (ADS)

Ye, Xi; Li, Jiang-tao; Liu, Jian-hua; Chen, Hai-long

2018-03-01

The motion of a bubble near the free surface is solved by the boundary element method based on the linear wave equation, and the influence of fluid compressibility on bubble dynamics is analyzed. Based on the solution of the bubble motion, the far-field radiation noise induced by the bubble is calculated using Kirchhoff moving boundary integral equation, and the influence of free surface on far-field noise is researched. As the results, the oscillation amplitude of the bubble is weakened in compressible fluid compared with that in incompressible fluid, and the free surface amplifies the effect of fluid compressibility. When the distance between the bubble and an observer is much larger than that between the bubble and free surface, the sharp wave trough of the sound pressure at the observer occurs. With the increment of the distance between the bubble and free surface, the time of the wave trough appearing is delayed and the value of the wave trough increase. When the distance between the observer and the bubble is reduced, the sharp wave trough at the observer disappears.

Element for use in an inductive coupler for downhole drilling components

DOEpatents

Hall, David R.; Hall, Jr., H. Tracy; Pixton, David S.; Dahlgren, Scott; Fox, Joe; Sneddon, Cameron

2006-08-29

The present invention includes an element for use in an inductive coupler in a downhole component. The element includes a plurality of ductile, generally U-shaped leaves that are electrically conductive. The leaves are less than about 0.0625" thick and are separated by an electrically insulating material. These leaves are aligned so as to form a generally circular trough. The invention also includes an inductive coupler for use in downhole components, the inductive coupler including an annular housing having a recess with a magnetically conductive, electrically insulating (MCEI) element disposed in the recess. The MCEI element includes a plurality of segments where each segment further includes a plurality of ductile, generally U-shaped electrically conductive leaves. Each leaf is less than about 0.0625" thick and separated from the otherwise adjacent leaves by electrically insulating material. The segments and leaves are aligned so as to form a generally circular trough. The inductive coupler further includes an insulated conductor disposed within the generally circular trough. A polymer fills spaces between otherwise adjacent segments, the annular housing, insulated conductor, and further fills the circular trough.

A standard description and costing methodology for the balance-of-plant items of a solar thermal electric power plant. Report of a multi-institutional working group

NASA Technical Reports Server (NTRS)

1983-01-01

Standard descriptions for solar thermal power plants are established and uniform costing methodologies for nondevelopmental balance of plant (BOP) items are developed. The descriptions and methodologies developed are applicable to the major systems. These systems include the central receiver, parabolic dish, parabolic trough, hemispherical bowl, and solar pond. The standard plant is defined in terms of four categories comprising (1) solar energy collection, (2) power conversion, (3) energy storage, and (4) balance of plant. Each of these categories is described in terms of the type and function of components and/or subsystems within the category. A detailed description is given for the BOP category. BOP contains a number of nondevelopmental items that are common to all solar thermal systems. A standard methodology for determining the costs of these nondevelopmental BOP items is given. The methodology is presented in the form of cost equations involving cost factors such as unit costs. A set of baseline values for the normalized cost factors is also given.

Development of steady-state model for MSPT and detailed analyses of receiver

NASA Astrophysics Data System (ADS)

Yuasa, Minoru; Sonoda, Masanori; Hino, Koichi

2016-05-01

Molten salt parabolic trough system (MSPT) uses molten salt as heat transfer fluid (HTF) instead of synthetic oil. The demonstration plant of MSPT was constructed by Chiyoda Corporation and Archimede Solar Energy in Italy in 2013. Chiyoda Corporation developed a steady-state model for predicting the theoretical behavior of the demonstration plant. The model was designed to calculate the concentrated solar power and heat loss using ray tracing of incident solar light and finite element modeling of thermal energy transferred into the medium. This report describes the verification of the model using test data on the demonstration plant, detailed analyses on the relation between flow rate and temperature difference on the metal tube of receiver and the effect of defocus angle on concentrated power rate, for solar collector assembly (SCA) development. The model is accurate to an extent of 2.0% as systematic error and 4.2% as random error. The relationships between flow rate and temperature difference on metal tube and the effect of defocus angle on concentrated power rate are shown.

A new candidate for a powerful wind detected in a bright IR-galaxy

NASA Astrophysics Data System (ADS)

Braito, V.; Reeves, J.; Severgnini, P.; Della Ceca, R.; Matzeu, G.; Ballo, L.; Nardini, E.

2017-10-01

We report the discovery of a new candidate for a powerful disk wind, in a nearby and bright starburst-AGN system: MCG-03-58-007. The winds strongly resembles the case of PDS456. MCG-03-58-007 is a relatively X-ray bright Seyfert 2 galaxy for which a deep Suzaku observation unveiled a highly curved spectrum due to a high column density absorber and an extremely steep intrinsic photon index (Gamma = 3). A detailed analysis showed that the steep spectrum is mainly driven by the presence of a deep absorption trough at 7.5-9 keV. This could be accounted for by the presence of a high ionisation, fast (v up to 0.2c) outflowing wind launched from within a few 100Rg from the black hole, whose kinetic output matches the prescription for significant feedback. New deep simultaneous XMM-Newton and NuSTAR observations provided the first direct measurement of the AGN luminosity and more importantly confirms the presence of a powerful X-ray wind. The new observations show rapid spectral variability, whose main driver appears to be the wind itself.

Time-Frequency Variability of Kuroshio Meanders in Tokara Strait

NASA Astrophysics Data System (ADS)

Nakamura, H.; Yamashiro, T.; Nishina, A.; Ichikawa, H.

2006-12-01

The Kuroshio path in the northern Okinawa Trough, Japan, located between the continental slope and Tokara Strait, exhibits meandering motions with largest displacements in the East China Sea; these motions have dominant periods in the broad range of 30-90 days. Understanding the dynamic nature of such meanders is crucial to predicting small and large meanders of the Kuroshio path off the south coast of Japan. Previous numerical simulations suggest that the Kuroshio path meanders in the northern Okinawa Trough become nonstationary in variance because of changes in background states of the Kuroshio in the northern Okinawa Trough, but a detailed analysis based on observed data has yet to be performed. The purpose of the present study is to provide a detailed description of the time-frequency variability of Kuroshio path meanders observed in Tokara Strait. Three Kuroshio indicators were subjected to wavelet analysis for the period 1984-2004: the Kuroshio Position Index (KPI) in Tokara Strait, Kuroshio Volume Transport (KVT) in Tokara Strait, and the basal current velocity of the Kuroshio on the continental slope in the northern Okinawa Trough. The 30-90 day variance of the KPI shows a season-fixed nature, with larger amplitudes in the period December-July. The amplitude of the variance in this phenomenon is also modulated by interannual variations, with small variance recorded during 1989-1992, large variance during 1993-1998, and a return to small variance from 1999-2003. This interannual variation is positively correlated with that of the KVT. The largest variance of the KPI during February-April precedes the largest volume transport in April-May by about 1 month, suggesting that eddy vorticity flux strengthens the mean current field. Previous numerical simulations reproduce the recirculation gyre as a cyclonic eddy in the area between the continental slope and Tokara Strait; this gyre is analogous to the northern recirculation gyre associated with the eastward jet. On the basis of data from a moored current-meter situated on the continental slope, the genesis of the 30-90 day meanders within Tokara Strait is ascribed to nonlinear energy transfer from 8-25 day meanders on the continental slope.

Comparison of home lead dust reduction techniques on hard surfaces: the New Jersey assessment of cleaning techniques trial.

PubMed Central

Rich, David Q; Rhoads, George G; Yiin, Lih-Ming; Zhang, Junfeng; Bai, Zhipeng; Adgate, John L; Ashley, Peter J; Lioy, Paul J

2002-01-01

High efficiency particulate air filter (HEPA) vacuums, which collect particles > 0.3 micro m, and trisodium phosphate (TSP), a detergent claimed to selectively remove lead, have been included in the HUD Guidelines for the Evaluation and Control of Lead Based Paint Hazards in Housing without systematic validation of their effectiveness. At the time the study was initiated, both HEPA vacuums and TSP were relatively expensive, they were not readily found in urban retail centers, and there were environmental concerns about the use and disposal of high-phosphate detergents. A randomized, controlled trial was conducted in urban high-risk homes in northern New Jersey to determine whether a more readily available and less expensive low-phosphate, non-TSP detergent and non-HEPA vacuum could perform as well as TSP and a HEPA vacuum in a cleaning protocol. Homes were randomized to one of three cleaning methods: TSP/HEPA vacuum, TSP/non-HEPA vacuum, or non-TSP/non-HEPA vacuum. Change in log-transformed lead loading was used in mixed models to compare the efficacy of the three cleaning techniques separately for uncarpeted floors, window sills, and window troughs. After we adjusted for baseline lead loading, the non-HEPA vacuum produced larger reductions on hard floors [19%; 95% confidence interval (CI), 3-38%], but the HEPA vacuum produced larger reductions on window sills (22%; 95% CI, 11-32%) and larger reductions on window troughs (16%; 95% CI, -4 to 33%). The non-TSP produced larger reductions on window troughs (21%; 95% CI, -2 to 50%), but TSP produced larger reductions on hard floors (5%; 95% CI, -12 to 19%) and window sills (8%; 95% CI, -5 to 20%). TSP/HEPA produced larger reductions on window sills (28%; 95% CI, 18-37%) and larger reductions on window troughs (2%; 95% CI, -24 to 23%), whereas the non-TSP/non-HEPA method produced larger reductions on hard floors (13%; 95% CI, -5 to 34%). Because neither vacuum nor detergent produced consistent results across surface types, the use of low-phosphate detergents and non-HEPA vacuums in a temporary control measure is supported. PMID:12204823

Comparison of home lead dust reduction techniques on hard surfaces: the New Jersey assessment of cleaning techniques trial.

PubMed

Rich, David Q; Rhoads, George G; Yiin, Lih-Ming; Zhang, Junfeng; Bai, Zhipeng; Adgate, John L; Ashley, Peter J; Lioy, Paul J

2002-09-01

High efficiency particulate air filter (HEPA) vacuums, which collect particles > 0.3 micro m, and trisodium phosphate (TSP), a detergent claimed to selectively remove lead, have been included in the HUD Guidelines for the Evaluation and Control of Lead Based Paint Hazards in Housing without systematic validation of their effectiveness. At the time the study was initiated, both HEPA vacuums and TSP were relatively expensive, they were not readily found in urban retail centers, and there were environmental concerns about the use and disposal of high-phosphate detergents. A randomized, controlled trial was conducted in urban high-risk homes in northern New Jersey to determine whether a more readily available and less expensive low-phosphate, non-TSP detergent and non-HEPA vacuum could perform as well as TSP and a HEPA vacuum in a cleaning protocol. Homes were randomized to one of three cleaning methods: TSP/HEPA vacuum, TSP/non-HEPA vacuum, or non-TSP/non-HEPA vacuum. Change in log-transformed lead loading was used in mixed models to compare the efficacy of the three cleaning techniques separately for uncarpeted floors, window sills, and window troughs. After we adjusted for baseline lead loading, the non-HEPA vacuum produced larger reductions on hard floors [19%; 95% confidence interval (CI), 3-38%], but the HEPA vacuum produced larger reductions on window sills (22%; 95% CI, 11-32%) and larger reductions on window troughs (16%; 95% CI, -4 to 33%). The non-TSP produced larger reductions on window troughs (21%; 95% CI, -2 to 50%), but TSP produced larger reductions on hard floors (5%; 95% CI, -12 to 19%) and window sills (8%; 95% CI, -5 to 20%). TSP/HEPA produced larger reductions on window sills (28%; 95% CI, 18-37%) and larger reductions on window troughs (2%; 95% CI, -24 to 23%), whereas the non-TSP/non-HEPA method produced larger reductions on hard floors (13%; 95% CI, -5 to 34%). Because neither vacuum nor detergent produced consistent results across surface types, the use of low-phosphate detergents and non-HEPA vacuums in a temporary control measure is supported.

Hydrocarbon prospectivity assessment of the Southern Pattani Trough, Gulf of Thailand

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mountford, N.

The Pattani Trough is an elongate north to south basin in the Gulf of Thailand offshore area that developed from Oligocene times onward. Numerous hydrocarbon discoveries, mainly gas, have been made within the Tertiary stratigraphic section in areas adjacent to the depocenter of the basin, but only dry holes have been drilled on the extreme basin margins and flanking platform areas. The southern Pattani Trough represents a [open quotes]transition zone[close quotes] in terms of potential hydrocarbon prospectivity between the low potential/high exploration risk basin marginal areas, and the high potential/low exploration risk basin marginal area. The development of hydrocarbon accumulationmore » potential within the southern Pattani Trough can be related to a number of major controlling factors. These include structure, which on a regional scale shows a marked influence of tectonic regime on depositional system development, and on a more local scale determines trap development; stratigraphy, which determines reservoir geometry and potential hydrocarbon source rock facies distribution; petrology, which exerts a major control on depth related reservoir quality; overpressure development, which controls local migration pathways for generated hydrocarbons, and locally provides very efficient trap seals; geochemical factors, related to potential source facies distribution, hydrocarbon type; and thermal maturation of the section. The above factors have been combined to define low-, medium-, and high-risk exploration [open quotes]play fairways[close quotes] within the prospectivity transition zone of the southern Pattani Trough.« less

Crustal structure and extension mode in the northwestern margin of the South China Sea

NASA Astrophysics Data System (ADS)

Gao, Jinwei; Wu, Shiguo; McIntosh, Kirk; Mi, Lijun; Liu, Zheng; Spence, George

2016-06-01

Combining multi-channel seismic reflection and gravity modeling, this study has investigated the crustal structure of the northwestern South China Sea margin. These data constrain a hyper-extended crustal area bounded by basin-bounding faults corresponding to an aborted rift below the Xisha Trough with a subparallel fossil ridge in the adjacent Northwest Sub-basin. The thinnest crust is located in the Xisha Trough, where it is remnant lower crust with a thickness of less than 3 km. Gravity modeling also revealed a hyper-extended crust across the Xisha Trough. The postrift magmatism is well developed and more active in the Xisha Trough and farther southeast than on the northwestern continental margin of the South China Sea; and the magmatic intrusion/extrusion was relatively active during the rifting of Xisha Trough and the Northwest Sub-basin. A narrow continent-ocean transition zone with a width of ˜65 km bounded seaward by a volcanic buried seamount is characterized by crustal thinning, rift depression, low gravity anomaly and the termination of the break-up unconformity seismic reflection. The aborted rift near the continental margin means that there may be no obvious detachment fault like that in the Iberia-Newfoundland type margin. The symmetric rift, extreme hyper-extended continental crust and hotter mantle materials indicate that continental crust underwent stretching phase (pure-shear deformation), thinning phase and breakup followed by onset of seafloor spreading and the mantle-lithosphere may break up before crustal-necking in the northwestern South China Sea margin.

Identification of large-scale meteorological patterns associated with extreme precipitation in the US northeast

NASA Astrophysics Data System (ADS)

Agel, Laurie; Barlow, Mathew; Feldstein, Steven B.; Gutowski, William J.

2018-03-01

Patterns of daily large-scale circulation associated with Northeast US extreme precipitation are identified using both k-means clustering (KMC) and Self-Organizing Maps (SOM) applied to tropopause height. The tropopause height provides a compact representation of the upper-tropospheric potential vorticity, which is closely related to the overall evolution and intensity of weather systems. Extreme precipitation is defined as the top 1% of daily wet-day observations at 35 Northeast stations, 1979-2008. KMC is applied on extreme precipitation days only, while the SOM algorithm is applied to all days in order to place the extreme results into the overall context of patterns for all days. Six tropopause patterns are identified through KMC for extreme day precipitation: a summertime tropopause ridge, a summertime shallow trough/ridge, a summertime shallow eastern US trough, a deeper wintertime eastern US trough, and two versions of a deep cold-weather trough located across the east-central US. Thirty SOM patterns for all days are identified. Results for all days show that 6 SOM patterns account for almost half of the extreme days, although extreme precipitation occurs in all SOM patterns. The same SOM patterns associated with extreme precipitation also routinely produce non-extreme precipitation; however, on extreme precipitation days the troughs, on average, are deeper and the downstream ridges more pronounced. Analysis of other fields associated with the large-scale patterns show various degrees of anomalously strong moisture transport preceding, and upward motion during, extreme precipitation events.

Large-Scale Meteorological Patterns Associated with Extreme Precipitation in the US Northeast

NASA Astrophysics Data System (ADS)

Agel, L. A.; Barlow, M. A.

2016-12-01

Patterns of daily large-scale circulation associated with Northeast US extreme precipitation are identified using both k-means clustering (KMC) and Self-Organizing Maps (SOM) applied to tropopause height. Tropopause height provides a compact representation of large-scale circulation patterns, as it is linked to mid-level circulation, low-level thermal contrasts and low-level diabatic heating. Extreme precipitation is defined as the top 1% of daily wet-day observations at 35 Northeast stations, 1979-2008. KMC is applied on extreme precipitation days only, while the SOM algorithm is applied to all days in order to place the extreme results into a larger context. Six tropopause patterns are identified on extreme days: a summertime tropopause ridge, a summertime shallow trough/ridge, a summertime shallow eastern US trough, a deeper wintertime eastern US trough, and two versions of a deep cold-weather trough located across the east-central US. Thirty SOM patterns for all days are identified. Results for all days show that 6 SOM patterns account for almost half of the extreme days, although extreme precipitation occurs in all SOM patterns. The same SOM patterns associated with extreme precipitation also routinely produce non-extreme precipitation; however, on extreme precipitation days the troughs, on average, are deeper and the downstream ridges more pronounced. Analysis of other fields associated with the large-scale patterns show various degrees of anomalously strong upward motion during, and moisture transport preceding, extreme precipitation events.

Comparison of the multi-scale features in two persistent heavy rainfall events in the middle and lower reaches of Yangtze River

NASA Astrophysics Data System (ADS)

Hui, Pinhong; Fang, Juan

2016-06-01

Two persistent heavy rainfall (PHR) events in the middle and lower reaches of Yangtze River (MLYR) occurring in June 1982 and 1998 are studied in this paper. Though both events happened in the Meiyu season, their large-scale background and developing processes were quite different. During the PHR event in 1982, the Lake Baikal area was occupied by a strong westerly trough and the western Pacific subtropical high (WPSH) was stronger and more westward-extending than the normal years. Under such a condition, the cold-dry air and warm-moist air were continuously transported to the MLYR and favored the PHR there. For the event in 1998, the WPSH was similar to that in 1982, while the westerly trough in the Lake Baikal area was comparatively weak and a shortwave trough situating in East China contributed to advect cold-dry air to the MLYR. It is found that the high-latitude trough was closely related to the 10-30-day low-frequency oscillation while the anomaly of WPSH was linked with the combined effect of both 30-60- and 10-30-day low-frequency oscillations in the PHR event in 1982. By contrast, the 60-day low-pass perturbation demonstrated positive impact on the westward extension of WPSH and development of the Baikal trough while the 30-60-day oscillation played a role in strengthening the shortwave trough in East China and the WPSH in the case of 1998. Though the low-latitude 30-60-day oscillations contributed to the intensification and westward extension of the WPSH in both PHR events, their evolution exhibited evident differences. In the 1982 case, the 30-60-day anomalies originated from the western Indian Ocean were much more like the Madden-Julian Oscillation, while its counterpart in the 1998 case was much more similar to the first mode of the boreal summer intraseasonal oscillation.

Late Weichselian ice-sheet dynamics and deglaciation history of the northern Svalbard margin

NASA Astrophysics Data System (ADS)

Fransner, O.; Noormets, R. R. N. N.; Flink, A.; Hogan, K.; Dowdeswell, J. A.; O'Regan, M.; Jakobsson, M.

2016-12-01

The glacial evolution of the northern Svalbard margin is poorly known compared with the western margin. Gravity cores, swath bathymetric, sub-bottom acoustic and 2D airgun data are used to investigate the Late Weichselian Svalbard-Barents Ice Sheet history on the northern Svalbard margin. Prograding sequences in Kvitøya and Albertini trough mouths (TMs) indicate ice streaming to the shelf edge multiple times during the Quaternary. While Kvitøya Trough has an associated trough-mouth fan (TMF), Albertini TM is cut back into the shelf edge. Down-faulted bedrock below Albertini TM suggests larger sediment accommodation space there, explaining the absence of a TMF. The bathymetry indicates that ice flow in Albertini Trough was sourced from Duvefjorden and Albertinibukta. Exposed crystalline bedrock likely kept the two ice flows separated before merging north of Karl XII-Øya. Subglacial landforms in Rijpfjorden and Duvefjorden indicate that both fjords accommodated northward-flowing ice streams during the LGM. The deeper fjord basin and higher elongation ratios of landforms in Duvefjorden suggest a more focused and/or larger ice flow there. Easily erodible sedimentary rocks are common in Duvefjorden, which may explain different ice flow dynamics in these fjords. Kvitøya TMF is flanked by gullies, probably formed through erosive downslope gravity flows triggered by sediment-laden meltwater during early deglaciation. Glacial landforms in Albertini Trough comprise retreat-related landforms indicating slow deglaciation. Iceberg scours in Albertini Trough suggest the importance of calving for mass-loss. Sets of De Geer moraines in Rijpfjorden imply that slow, grounded retreat continued in <210 m water depth. Lack of retreat-related landforms in deeper areas of Rijpfjorden and in Duvefjorden indicates floating glacier fronts influenced by calving. 14C ages suggest that deglaciation of inner Rijpfjorden and central Duvefjorden were complete before 10,434 cal a BP and 10,779 cal a BP respectively.

A Quasi-Experiment To Study the Impact of Vancomycin Area under the Concentration-Time Curve-Guided Dosing on Vancomycin-Associated Nephrotoxicity

PubMed Central

Finch, Natalie A.; Zasowski, Evan J.; Murray, Kyle P.; Mynatt, Ryan P.; Zhao, Jing J.; Yost, Raymond; Pogue, Jason M.

2017-01-01

ABSTRACT Evidence suggests that maintenance of vancomycin trough concentrations at between 15 and 20 mg/liter, as currently recommended, is frequently unnecessary to achieve the daily area under the concentration-time curve (AUC24) target of ≥400 mg · h/liter. Many patients with trough concentrations in this range have AUC24 values in excess of the therapeutic threshold and within the exposure range associated with nephrotoxicity. On the basis of this, the Detroit Medical Center switched from trough concentration-guided dosing to AUC-guided dosing to minimize potentially unnecessary vancomycin exposure. The primary objective of this analysis was to assess the impact of this intervention on vancomycin-associated nephrotoxicity in a single-center, retrospective quasi-experiment of hospitalized adult patients receiving intravenous vancomycin from 2014 to 2015. The primary analysis compared the incidence of nephrotoxicity between patients monitored by assessment of the AUC24 and those monitored by assessment of the trough concentration. Multivariable logistic and Cox proportional hazards regression examined the independent association between the monitoring strategy and nephrotoxicity. Secondary analysis compared vancomycin exposures (total daily dose, AUC, and trough concentrations) between monitoring strategies. Overall, 1,280 patients were included in the analysis. After adjusting for severity of illness, comorbidity, duration of vancomycin therapy, and concomitant receipt of nephrotoxins, AUC-guided dosing was independently associated with lower nephrotoxicity by both logistic regression (odds ratio, 0.52; 95% confidence interval [CI], 0.34 to 0.80; P = 0.003) and Cox proportional hazards regression (hazard ratio, 0.53; 95% CI, 0.35 to 0.78; P = 0.002). AUC-guided dosing was associated with lower total daily vancomycin doses, AUC values, and trough concentrations. Vancomycin AUC-guided dosing was associated with reduced nephrotoxicity, which appeared to be a result of reduced vancomycin exposure. PMID:28923869

Association of the clinical efficacy of vancomycin with the novel pharmacokinetic parameter area under the trough level (AUTL) in elderly patients with hospital-acquired pneumonia.

PubMed

Fukumori, S; Tsuji, Y; Mizoguchi, A; Kasai, H; Ishibashi, T; Iwamura, N; To, H

2016-08-01

The pharmacokinetic-pharmacodynamic parameter that best predicts the efficacy of vancomycin is the ratio of the area under the concentration versus time curve (AUC) to the minimum inhibitory concentration (MIC). A 24-h AUC (AUC24 )/MIC ratio ≥ 400 was recommended in an American consensus review, but vancomycin treatment occasionally fails despite maintenance of AUC24 /MIC ≥ 400. We evaluated the association between clinical efficacy of vancomycin and two novel pharmacokinetic parameters, the 'area under the trough level' (AUTL) and the 'area above the trough level' (AATL), in hospitalized elderly patients with methicillin-resistant Staphylococcus aureus (MRSA) pneumonia. The subjects were hospitalized elderly patients who were administered vancomycin for treatment of MRSA pneumonia between 2006 and 2012 at Sasebo Chuo Hospital (Nagasaki, Japan). Pharmacokinetic parameters of vancomycin were estimated for each patient by Bayesian analysis using population pharmacokinetic parameters for Japanese patients. Based on the patient-specific parameters thus obtained, AUC24 values were calculated as the vancomycin dosage divided by vancomycin clearance. AUTL was calculated as the trough serum concentration multiplied by 24 h, whereas AATL was calculated by subtracting AUTL from AUC24 . Logistic regression analysis demonstrated that efficacy of vancomycin was more strongly associated with AUTL than AUC24 . The optimal cut-off value of AUTL was 331 μg∙h/mL, which means that the optimal cut-off value of the trough serum concentration was 13·8 μg/mL. Efficacy of vancomycin was associated with AUTL, a novel pharmacokinetic parameter. Determining the target AUTL or trough concentration may enhance the efficacy of vancomycin therapy in elderly patients with MRSA pneumonia. Given that nephrotoxicity may increase with a Ctrough in excess of 15 μg/mL, this level should ideally not be exceeded. © 2016 John Wiley & Sons Ltd.

Effect of raltegravir on the total and unintegrated proviral HIV DNA during raltegravir-based HAART.

PubMed

Nicastri, Emanuele; Tommasi, Chiara; Abbate, Isabella; Bonora, Stefano; Tempestilli, Massimo; Bellagamba, Rita; Viscione, Magdalena; Rozera, Gabriella; Gallo, Anna L; Ivanovic, Jelena; Amendola, Alessandra; Pucillo, Leopoldo; Di Perri, Giovanni; Capobianchi, Maria R; Narciso, Pasquale

2011-01-01

Raltegravir is the first approved antiretroviral able to prevent HIV genome integration into the host chromosomes. The aim of the study is to test if raltegravir plasma concentrations can be associated with proviral DNA decline during raltegravir-based salvage therapy. A total of 33 multidrug-resistant HIV-infected patients were enrolled in a longitudinal open-label pilot study and completed a 24-week follow-up. The CD4(+) T-cell count, plasma viral load, proviral HIV DNA and two-long-terminal repeat (2-LTR) circular forms were assessed at baseline, day 14, 30, 60, 90 and 180. The raltegravir trough concentration (C (trough)) was measured by HPLC-ultraviolet and patients were divided into two groups according to the median raltegravir C (trough). The mean±SD values of baseline HIV RNA, CD4(+) T-cell count and HIV DNA were 4.4±0.82 log copies/ml, 256±177 cells/mm(3) , and 2,668±4,721 copies/10(6) peripheral blood mononuclear cells, respectively. Despite a transient increase of total DNA at week 2, a marked proviral DNA decay (P=0.01) with an increase of the 2-LTR unintegrated/total DNA ratio (P=0.06) over time was observed. At univariate analysis, no correlation between raltegravir C(trough) and classical virological parameters was observed. Nevertheless, the decay of proviral HIV DNA was more pronounced in patients displaying C(trough)<158 ng/ml with respect to those with C(trough)>158 ng/ml (P=0.046). Successful raltegravir-based therapy produces a significant decline in proviral DNA and is associated with an increase of the unintegrated/total DNA ratio. Further studies are necessary to define the possible role of pharmacokinetic raltegravir monitoring and the biological meaning of unintegrated proviral DNA. © 2011 International Medical Press

A Quasi-Experiment To Study the Impact of Vancomycin Area under the Concentration-Time Curve-Guided Dosing on Vancomycin-Associated Nephrotoxicity.

PubMed

Finch, Natalie A; Zasowski, Evan J; Murray, Kyle P; Mynatt, Ryan P; Zhao, Jing J; Yost, Raymond; Pogue, Jason M; Rybak, Michael J

2017-12-01

Evidence suggests that maintenance of vancomycin trough concentrations at between 15 and 20 mg/liter, as currently recommended, is frequently unnecessary to achieve the daily area under the concentration-time curve (AUC 24 ) target of ≥400 mg · h/liter. Many patients with trough concentrations in this range have AUC 24 values in excess of the therapeutic threshold and within the exposure range associated with nephrotoxicity. On the basis of this, the Detroit Medical Center switched from trough concentration-guided dosing to AUC-guided dosing to minimize potentially unnecessary vancomycin exposure. The primary objective of this analysis was to assess the impact of this intervention on vancomycin-associated nephrotoxicity in a single-center, retrospective quasi-experiment of hospitalized adult patients receiving intravenous vancomycin from 2014 to 2015. The primary analysis compared the incidence of nephrotoxicity between patients monitored by assessment of the AUC 24 and those monitored by assessment of the trough concentration. Multivariable logistic and Cox proportional hazards regression examined the independent association between the monitoring strategy and nephrotoxicity. Secondary analysis compared vancomycin exposures (total daily dose, AUC, and trough concentrations) between monitoring strategies. Overall, 1,280 patients were included in the analysis. After adjusting for severity of illness, comorbidity, duration of vancomycin therapy, and concomitant receipt of nephrotoxins, AUC-guided dosing was independently associated with lower nephrotoxicity by both logistic regression (odds ratio, 0.52; 95% confidence interval [CI], 0.34 to 0.80; P = 0.003) and Cox proportional hazards regression (hazard ratio, 0.53; 95% CI, 0.35 to 0.78; P = 0.002). AUC-guided dosing was associated with lower total daily vancomycin doses, AUC values, and trough concentrations. Vancomycin AUC-guided dosing was associated with reduced nephrotoxicity, which appeared to be a result of reduced vancomycin exposure. Copyright © 2017 American Society for Microbiology.

The Relationship Between Anomalous Presummer Extreme Rainfall Over South China and Synoptic Disturbances

NASA Astrophysics Data System (ADS)

Huang, Ling; Luo, Yali; Zhang, Da-Lin

2018-04-01

A spectral analysis of daily rainfall data has been performed to investigate extreme rainfall events in south China during the presummer rainy seasons between 1998 and 2015 (excluding 1999, 2006, 2011, and 2014). The results reveal a dominant frequency mode at the synoptic scale with pronounced positive rainfall anomalies. By analyzing the synoptic-scale bandpass-filtered anomalous circulations, 24 extreme rainfall episodes (defined as those with a daily rainfall amount in the top 5%) are categorized into "cyclone" (15) and "trough" (8) types, with the remaining events as an "anticyclone" type, according to the primary anomalous weather system contributing to each extreme rainfall episode. The 15 cyclone-type episodes are further separated into (11) lower- and (4) upper-tropospheric migratory anomalies. An analysis of their anomalous fields shows that both types could be traced back to the generation of cyclonic anomalies downstream of the Tibetan Plateau, except for two episodes of lower-tropospheric migratory anomalies originating over the South China Sea. However, a lower-tropospheric cyclonic anomaly appears during all phases in the former type, but only in the wettest phase in the latter type, with its peak disturbance occurring immediately beneath an upper-level warm anomaly. The production of extreme rainfall in the trough-type episodes is closely related to a deep trough anomaly extending from an intense cyclonic anomaly over north China, which in turn could be traced back to a midlatitude Rossby wave train passing by the Tibetan Plateau. The results have important implications for understanding the origin, structure, and evolution of synoptic disturbances associated with the presummer extreme rainfall in south China.

A pharmacokinetic and pharmacodynamic comparison of immediate-release metoprolol and extended-release metoprolol CR/XL in patients with suspected acute myocardial infarction: a randomized, open-label study.

PubMed

Karlson, Björn W; Dellborg, Mikael; Gullestad, Lars; Aberg, Jan; Sugg, Jennifer; Herlitz, Johan

2014-01-01

Previous metoprolol studies in myocardial infarction patients were performed with immediate-release (IR) metoprolol. This study aims to evaluate if extended-release metoprolol CR/XL once daily gives a similar β-blockade over 24 h compared to multiple dosing of metoprolol IR. After 2 days of routine metoprolol treatment, 27 patients with suspected acute myocardial infarction were randomized to open-label treatment with metoprolol IR (50 mg four times daily or 100 mg twice daily) or metoprolol CR/XL 200 mg once daily for 3 days. Metoprolol CR/XL 200 mg once daily gave more pronounced suppression of peak heart rate, with lower peak and less variation in peak to trough plasma levels. There were no differences in AUC between the CR/XL and IR formulations, although the trough plasma metoprolol levels were comparable for metoprolol CR/XL 200 mg once daily and metoprolol IR 50 mg four times daily, but lower for metoprolol IR 100 mg twice daily. Both treatments were well tolerated. Metoprolol CR/XL 200 mg once daily showed lower peak and less variation in peak to trough plasma levels compared to multiple dosing of metoprolol IR with the same AUC. This was accompanied by a more uniform β-blockade over time, which was reflected by heart rate, and a more pronounced suppression of peak heart rate with similar tolerability. This suggests metoprolol CR/XL may be used as an alternative to metoprolol IR in patients with myocardial infarction. © 2013 S. Karger AG, Basel.

Revisiting Parabolic Trough Concentrators for Industrial Process Heat in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Turchi, Craig S.; Kurup, Parthiv; Zhu, Guangdong

After significant interest in the 1970s, but relatively few deployments, the use of concentrating solar collectors for thermal applications, including enhanced oil recovery, desalination, and industrial process heat (IPH), is again increasing in global interest. In particular, recent advances in collector design and manufacturing have led to reduced cost per square meter of aperture area. In this study, analysis of a modern parabolic trough that is suited for use in small solar IPH (SIPH) applications predicts that the installed solar field cost can be as low as $170/m2. A slightly higher cost of $200/m2 is estimated for facilities typical ofmore » a SIPH plant size. Full project costs will include additional costs for contingency, piping and heat exchanger interface, and project indirect costs. The cost for solar-generated heat by SIPH is quantified by defining the levelized cost of heat (LCOH). California offers a favorable environment for SIPH given its good insolation, gas prices typically higher than the national average, and policies promoting solar-thermal deployment. Given historically low gas prices, competing with natural gas remains the primary challenge to deployment. However, this study finds that the solar LCOH for many regions in California is lower than the LCOH from natural gas, using a representative installed solar hardware price and the average price for industrial natural gas in California. Lastly, modification are in progress to the parabolic trough model within NREL's System Advisor Model (SAM) to allow users to more easily predict performance for these steam-generation applications.« less

Scaly-skinned Mars

NASA Technical Reports Server (NTRS)

2002-01-01

[figure removed for brevity, see original site]

The style of erosion along the highlands-lowlands boundary of southern Elysium Planitia has produced a strange pattern of troughs that look like the skin of a reptile. In reality, a very clear process of landscape degradation is evident in this image. Some process has produced polygon-shaped troughs that create zones of weakness in the uppermost crust. It is likely that wind-blown particles deepen and widen the troughs, producing isolated knobs and mesas. Ultimately, the erosional reworking of the landscape is so complete that all signs of the upper layer are removed, leaving the smooth lowland surface to the north.

Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time.

NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS) was developed by Arizona State University, Tempe, in collaboration with Raytheon Santa Barbara Remote Sensing. The THEMIS investigation is led by Dr. Philip Christensen at Arizona State University. Lockheed Martin Astronautics, Denver, is the prime contractor for the Odyssey project, and developed and built the orbiter. Mission operations are conducted jointly from Lockheed Martin and from JPL, a division of the California Institute of Technology in Pasadena.

Withdrawal of immunomodulators after co-treatment does not reduce trough level of infliximab in patients with Crohn's disease.

PubMed

Drobne, David; Bossuyt, Peter; Breynaert, Christine; Cattaert, Tom; Vande Casteele, Niels; Compernolle, Griet; Jürgens, Matthias; Ferrante, Marc; Ballet, Vera; Wollants, Willem-Jan; Cleynen, Isabelle; Van Steen, Kristel; Gils, Ann; Rutgeerts, Paul; Vermeire, Severine; Van Assche, Gert

2015-03-01

The addition of immunomodulators increases the efficacy of maintenance therapy with infliximab for up to 1 year in patients with Crohn's disease who have not been previously treated with immunomodulators. However, there are questions about the effect of withdrawing immunomodulator therapy from these patients. We studied the effects of treatment with infliximab and immunomodulators (co-treatment) and then immunomodulator withdrawal on long-term outcomes of patients, as well as trough levels of infliximab and formation of anti-infliximab antibodies (ATI). In a retrospective study with the median follow-up period of 34 months (interquartile range, 19-58 months), we analyzed data from 223 patients treated for Crohn's disease between May 1999 and December 2010 at the University Hospitals, Leuven, Belgium (65 received infliximab monotherapy, 158 received infliximab and an immunomodulator). Trough levels of infliximab and levels of ATI were measured in blood samples collected from 117 patients throughout co-treatment, as well as the time of immunomodulator withdrawal and after withdrawal. Patients receiving co-treatment had higher trough levels of infliximab (adjusted mean increase, 1.44-fold) than those receiving infliximab monotherapy (95% confidence interval [CI], 1.07-1.92; P = .02). A smaller percentage of patients receiving co-treatment developed ATI (35 of 158, 22%) than those receiving infliximab monotherapy (25 of 65, 38%; P = .01). Among co-treated patients, levels of infliximab remained stable after immunomodulators were withdrawn (before: 3.2 μg/mL; 95% CI, 1.6-5.8 μg/mL and after: 3.7 μg/mL; 95% CI, 1.3-6.3 μg/mL; P = .70). After withdrawal of immunomodulators, 45 of 117 patients (38%) required increasing doses of infliximab, and 21 of 117 (18%) discontinued infliximab. At the time of immunomodulator withdrawal, trough levels of infliximab and C-reactive protein were most strongly associated with response to infliximab thereafter. In a retrospective analysis, we confirmed that withdrawal of immunomodulators after at least 6 months (median, 13 months) of co-treatment with infliximab does not reduce the trough levels of infliximab in patients with Crohn's disease. Detectable trough levels of infliximab at the time of immunomodulator withdrawal are associated with long-term response. Copyright © 2015 AGA Institute. Published by Elsevier Inc. All rights reserved.

Structural characteristics around the frontal thrust along the Nankai Trough revealed by bathymetric and seismic reflection survey

NASA Astrophysics Data System (ADS)

Yamashita, M.; Nakanishi, A.; Moore, G. F.; Kodaira, S.; Nakamura, Y.; Miura, S.; Kaneda, Y.

2016-12-01

Great earthquakes with tsunamis with recurrence intervals of 100-200 years have occurred along the Nankai Trough near central Japan where the Shikoku Basin is subducting with thick sediments on the Philippine Sea plate. To predict the exact height of the tsunami on the coast region generated by these large ruptures, it is important to estimate the vertical deformation that occurs on the seaward end of the rupture area. Recent drilling results have also yielded evidence not only of splay faults that generate tsunamigenic rupture, but also new evidence of tsunamigenic rupture along the frontal thrust at the trench axis in the Nankai Trough. In order to understand the deformation around the frontal thrust at the trench axis, we conducted a dense high-resolution seismic reflection survey with 10-20 km spacing over 1500 km of line length during 2013 and 2014. Clear seismic reflection images of frontal thrusts in the accretionary prism and subducting Shikoku Basin, image deformation along the trench axis between off Muroto Cape and off Ashizuri Cape. The cumulative displacement along the frontal thrust and second thrust are measured from picked distinct reflectors in depth-converted profiles. The average value of cumulative displacement of the frontal thrust is more than 100 m within 2 km depth beneath the seafloor. The location of highest displacement of 300 m displacement agree with the seaward end of slip distribution of the 1946 Nankai event calculated by numerical simulations. We also evaluate the seaward structure for understanding the future rupture distribution. The protothrust zone (PTZ) consisting of many incipient thrusts is identifiable in the portion of trough-fill sediments seaward of the frontal thrust. In order to emphasize the characteristics of frontal thrust and PTZ, we construct the detailed relief image for focusing on the lineated slope of the PTZ at the trough axis. Although our surveys covered a part of Nankai seismogenic zone, it is important to evaluate the initiation and evolution of frontal thrust at the toe of Nankai trough axis. This study is part of "Research project for compound disaster mitigation on the great earthquakes and tsunamis around the Nankai Trough region" funded by the Ministry of Education, Culture, Sports, Science, and Technology of Japan.

Regional distribution of volcaniclastic layer and its implication for segmentation of the Nankai seismogenic zone

NASA Astrophysics Data System (ADS)

Sasaki, T.; Lim, J.; Higashi, M.; Park, J.

2010-12-01

The Nankai Trough is known as one of the best-suited convergent plate margins for studying accretionary prism growth as well as subduction zone earthquakes. Along the Nankai accretionary margin off southwest Japan, the Shikoku Basin which formed 26-15 Ma as backarc spreading in the Philippine Sea Plate is being subducted about 4 cm/year to the northwest. The Deep Sea Drilling Project (DSDP) and Ocean Drilling Program (ODP) penetrated the Nankai accretionary prism and the incoming sedimentary section along the Ashizuri and Muroto transects, off Shikoku Island. Also, Integrated Ocean Drilling Program (IODP), which represented just one part of a multi-stage project known as the Nankai Trough Seismogenic Zone Experiment (NanTroSEIZE) has been conducting drilling cruises now. IODP Expedition 322 in 2009, the coring was carried out at two drilling sites on the northern part of the Shikoku Basin in the subducting Philippine Sea plate. One of the major achievements of Expedition 322 is a discovery of late Miocene (10.2-7.6 Ma) tuffaceous and volcaniclastic sandstone layer (Underwood et al., IODP Prel. Rept. 322, 2009) that has not been previously recognized in the Nankai Trough. Based on age and volcanic sand content analysis, these volcaniclastic layers were unique to the Shikoku Basin off Kii Peninsula. The closest source of this volcanic layer was supposed to be the Izu-Bonin arc. Subducted sediments ultimately affect subduction zone geochemistry, thermal structure, and seismogenesis. High porosity of the volcaniclastic sandstone layer suggests the transportation of fluid to the subduction zone, it might affect the initiation and evolution of the decollement zone or plate boundary fault in the Nankai Trough. We interpreted single channel and multichannel seismic reflection profiles that have been acquired in the Nankai Trough margin by Japan Agency for Marine-Earth Science and Technology (JAMSTEC) since the year of 1997. We tried to map the major seismic layers such as volcaniclastic layer, volcanic ash layer and turbidite layers which were found at drilling sites in the IODP Expedition 322 in the northern Shikoku Basin. As a result, we recognized that these prominent seismic layers are widely distributed in the northern Shikoku Basin. In this talk, we will show specific seismic layers directly connecting to the decollement at the Nankai Trough axis, and discuss its implications for subduction processes in the Nankai Trough margin.

Interplate locking derived from seafloor geodetic measurement at the shallow subduction zone of the northernmost Suruga Trough, Japan

NASA Astrophysics Data System (ADS)

Yasuda, K.; Tadokoro, K.; Ikuta, R.; Watanabe, T.; Nagai, S.; Sayanagi, K.

2013-12-01

Observation of seafloor crustal deformation is crucial for megathrust earthquake because most of the focal areas are located below seafloor. Seafloor crustal deformation can be observed GPS/Acoustic technique, and this technique has been carried out at subduction margins in Japan, e.g., Japan Trench, Suruga Trough, and Nankai Trough. At the present, the accuracy of seafloor positioning is one to several centimeters for each epoch. Velocity vectors at seafloor site are estimated through repeated observations. Co- and post- seismic slip distribution and interseismic deformation are estimated from results of seafloor geodetic measurement (e.g., Iinuma et al., 2012; Tadokoro et al., 2012). We repeatedly observed seafloor crustal deformations at two sites across the Suruga Trough from 2005 to investigate interplate locking condition at the focal area of the anticipated megathrust, Tokai, earthquake. We observed 12 and 16 times at an east site of the Suruga Trough (SNE) and at an west site of the Suruga Trough (SNW), respectively. We reinstalled seafloor benchmarks at both sites because of run out of batteries in 2012. We calculated and removed the bias between the old and new seafloor benchmarks. Furthermore, we evaluated two type of analysis. One is Fixed triangular configuration Analysis (FTA). When we determine the seafloor benchmark position, we fix the triangular configuration of seafloor units averaging all the measurements to improve trade-off relation between seafloor benchmark position and sound speed structure. Sound speed structure is assumed to be horizontal layered structure. The other one is Fixed Triangle and Gradient structure of sound speed structure (FTGA). We fixed triangular configuration same as FTA. Sound speed structure is assumed to have gradient structure. Comparing FTA with FTGA, the RMS of horizontal position analyzed through FTA is smaller than that through FTGA at SNE site. On the other hand, the RMS of horizontal position analyzed through FTA is larger than that through FTGA at SNW site. We estimated the displacement velocities with relative to the Amurian plate from the result of repeated observation. The estimated displacement velocity vectors at SNE and SNW are 42×8 mm/y to N94W direction and 46×13 mm/y to N77W direction, respectively. The directions are the same as those measured at the on-land GPS stations. The magnitudes of velocity vector indicate significant shortening by approximately 11 mm/y between SNW and on-land GPS stations at the western part of the Suruga Trough. We also calculated the theoretical surface deformation pattern to depict the interplate locking condition. These results show that the plate interface at the shallow zone of the northernmost Suruga trough is strongly locked.

Cycling of sulfur in subduction zones: The geochemistry of sulfur in the Mariana Island Arc and back-arc trough

NASA Astrophysics Data System (ADS)

Alt, Jeffrey C.; Shanks, Wayne C., III; Jackson, Michael C.

1993-10-01

The sulfur contents and sulfur isotopic compositions of 24 glassy submarine volcanics from the Mariana Island Arc and back-arc Mariana Trough were determined in order to investigate the hypothesis that subducted seawater sulfur (delta S-34 = 21 parts per thousand) is recycled through arc volcanism. Our results for sulfur are similar to those for subaerial arc volcanics: Mariana Arc glasses are enriched in S-34(delta S-34 = up to 10.3 parts per thousand, mean = 3.8 parts per thousand) and depleted in S(20-290 ppm, mean = 100 ppm) relative to mid ocean ridge basalt (MORB)(850 ppm S, delta S-34 = 0.1 +/- 0.5 parts per thousand). The bac-arc trough basalts contain 200-930 ppm S and have delta S-34 values of 1.1 +/- 0.5 parts per thousand, which overlap those for the arc and MORB. The low sulfur contents of the arc and some of the trough glasses are attributed to (1) early loss of small amounts of sulfur through separation of immiscible sulfide and (2) later vapor-melt equilibrium control of sulfur contents and loss of sulfur in a vapor phase from sulfide-undersaturated melts near the minimum in sulfur solubility at fO2 is approximately equal to NNO (nickel-nickel oxide). Although these processes removed sulfur from the melts their effects on the sulfur isotopic compositions of the melts were minimal. Positive trends of delta S-34 with Sr-87/Sr-86 large ion lithophile element (LILE) and Light rare earth elements (LREE) contents of the arc volcanics are consistent with a metasomatic seawater sulfur component in the depleted sub-arc mantle source. The lack of a S-34-rich slab signature in the trough lavas may be attributed to equilibration of metasomatic fluid with mantle material along the longer pathway from the slab to the source of the trough volcanics. Sulfur is likely to have been transported into the mantle wedge by metasomatic fluid derived from subducted sediments and pore fluids. Gases extracted from vesicles in arc and back-arc samples are predominantly H2O, with minor CO2 and traces of H2S and SO2.CO2 in the arc and back-arc rocks has delta C-13 values of -2.1 to 13.1 parts per thousand, similar to MORB. These data suggest that degassing of CO2 could explain the slightly lower delta C-13 values for some Mariana Trough volcanic glasses, and that incorporation of subduction-derived organic carbon into the Mariana trough mantle source may not be necessary. More analyses are required to resolve this question, however.

Potentiometric surfaces, summer 2013 and winter 2015, and select hydrographs for the Southern High Plains aquifer, Cannon Air Force Base, Curry County, New Mexico

USGS Publications Warehouse

Collison, Jake

2016-04-07

Cannon Air Force Base (Cannon AFB) is located in the High Plains physiographic region of east-central New Mexico, about 5 miles west of Clovis, New Mexico. The area surrounding Cannon AFB is primarily used for agriculture, including irrigated cropland and dairies. The Southern High Plains aquifer is the principal source of water for Cannon AFB, for the nearby town of Clovis, and for local agriculture and dairies. The Southern High Plains aquifer in the vicinity of Cannon AFB consists of three subsurface geological formations: the Chinle Formation of Triassic age, the Ogallala Formation of Tertiary age, and the Blackwater Draw Formation of Quaternary age. The Ogallala Formation is the main water-yielding formation of the Southern High Plains aquifer. Groundwater-supplied, center-pivot irrigation dominates pumping from the Southern High Plains aquifer in the area surrounding Cannon AFB, where the irrigation season typically extends from early March through October. The U.S. Geological Survey has been monitoring groundwater levels in the vicinity of Cannon AFB since 1954 and has developed general potentiometric-surface maps that show groundwater flow from northwest to southeast in the study area. While previous potentiometric-surface maps show the general direction of groundwater flow, a denser well network is needed to show details of groundwater flow at a local scale. Groundwater levels were measured in 93 wells during summer 2013 and 100 wells during winter 2015.The summer and winter potentiometric-surface maps display the presence of what is interpreted to be a groundwater trough trending from the northwest to the southeast through the study area. This groundwater trough may be the hydraulic expression of a Tertiary-age paleochannel. Groundwater north of the trough flows in a southerly direction into the trough, and groundwater south of the trough flows in an easterly direction into the trough.During the 18-month period between summer 2013 and winter 2015, changes in groundwater levels ranged from a rise of 10.0 to a decline of 3.8 feet. The regions to the north and south of the groundwater trough contained the majority of the rises in groundwater levels, whereas the regions within the trough contained the majority of the declines in groundwater levels. In contrast, the long-term groundwater-level trend in wells with 20 to 60 years of record is a steady decline in average annual water levels, with declines ranging from 0.41 to 2.81 feet per year. Overall, the northwestern part of the study area exhibits the smallest average annual declines, while the southeastern part of the study area exhibits the largest average annual declines.

Quasar outflows and AGN feedback in the extreme UV: HST/COS observations of HE 0238-1904

NASA Astrophysics Data System (ADS)

Arav, Nahum; Borguet, Benoit; Chamberlain, Carter; Edmonds, Doug; Danforth, Charles

2013-12-01

Spectroscopic observations of quasar outflows at rest-frame 500-1000 Å have immense diagnostic power. We present analyses of such data, where absorption troughs from O IV and O IV* allow us to obtain the distance of the outflows from the AGN and troughs from Ne VIII and Mg X reveal the warm absorber phase of the outflow. Their inferred column densities, combined with those of O VI, N IV and H I, yield two important results. (1) The outflow shows two ionization phases, where the high-ionization phase carries the bulk of the material. This is similar to the situation seen in X-ray warm absorber studies. Furthermore, the low-ionization phase is inferred to have a volume filling factor of 10-5-10-6. (2) We determine a distance of 3000 pc from the outflow to the central source using the O IV*/O IV column density ratio and the knowledge of the ionization parameter. Since this is a typical high-ionization outflow, we can determine robust values for the outflow's mass flux and kinetic luminosity of 40 M⊙ yr-1 and 1045 erg s-1, respectively, where the latter is roughly equal to 1 per cent of the bolometric luminosity. Such a large kinetic luminosity and mass flow rate measured in a typical high-ionization wind suggest that quasar outflows are a major contributor to AGN feedback mechanisms.

Study of Using Solar Thermal Power for the Margarine Melting Heat Process.

PubMed

Sharaf Eldean, Mohamed A; Soliman, A M

2015-04-01

The heating process of melting margarine requires a vast amount of thermal energy due to its high melting point and the size of the reservoir it is contained in. Existing methods to heat margarine have a high hourly cost of production and use fossil fuels which have been shown to have a negative impact on the environment. Thus, we perform an analytical feasibility study of using solar thermal power as an alternative energy source for the margarine melting process. In this study, the efficiency and cost effectiveness of a parabolic trough collector (PTC) solar field are compared with that of a steam boiler. Different working fluids (water vapor and Therminol-VP1 heat transfer oil (HTO)) through the solar field are also investigated. The results reveal the total hourly cost ($/h) by the conventional configuration is much greater than the solar applications regardless of the type of working fluid. Moreover, the conventional configuration causes a negative impact to the environment by increasing the amount of CO 2 , CO, and NO 2 by 117.4 kg/day, 184 kg/day, and 74.7 kg/day, respectively. Optimized period of melt and tank volume parameters at temperature differences not exceeding 25 °C are found to be 8-10 h and 100 m 3 , respectively. The solar PTC operated with water and steam as the working fluid is recommended as a vital alternative for the margarine melting heating process.

IEA/SPS 500 kW distributed collector system

NASA Technical Reports Server (NTRS)

Neumann, T. W.; Hartman, C. D.

1980-01-01

Engineering studies for an International Energy Agency project for the design and construction of a 500 kW solar thermal electric power generation system of the distributed collector system (DCS) type are reviewed. The DCS system design consists of a mixed field of parabolic trough type solar collectors which are used to heat a thermal heat transfer oil. Heated oil is delivered to a thermocline storage tank from which heat is extracted and delivered to a boiler by a second heat transfer loop using the same heat transfer oil. Steam is generated in the boiler, expanded through a steam turbine, and recirculated through a condenser system cooled by a wet cooling tower.

Environmental dust effects on aluminum surfaces in humid air ambient.

PubMed

Yilbas, Bekir Sami; Hassan, Ghassan; Ali, Haider; Al-Aqeeli, Nasser

2017-04-05

Environmental dusts settle on surfaces and influence the performance of concentrated solar energy harvesting devices, such as aluminum troughs. The characteristics of environmental dust and the effects of mud formed from the dust particles as a result of water condensing in humid air conditions on an aluminum wafer surface are examined. The dissolution of alkaline and alkaline earth compounds in water condensate form a chemically active mud liquid with pH 8.2. Due to gravity, the mud liquid settles at the interface of the mud and the aluminum surface while forming locally scattered patches of liquid films. Once the mud liquid dries, adhesion work to remove the dry mud increases significantly. The mud liquid gives rise to the formation of pinholes and local pit sites on the aluminum surface. Morphological changes due to pit sites and residues of the dry mud on the aluminum surface lower the surface reflection after the removal of the dry mud from the surface. The characteristics of the aluminum surface can address the dust/mud-related limitations of reflective surfaces and may have implications for the reductions in the efficiencies of solar concentrated power systems.

Environmental dust effects on aluminum surfaces in humid air ambient

PubMed Central

Yilbas, Bekir Sami; Hassan, Ghassan; Ali, Haider; Al-Aqeeli, Nasser

2017-01-01

Environmental dusts settle on surfaces and influence the performance of concentrated solar energy harvesting devices, such as aluminum troughs. The characteristics of environmental dust and the effects of mud formed from the dust particles as a result of water condensing in humid air conditions on an aluminum wafer surface are examined. The dissolution of alkaline and alkaline earth compounds in water condensate form a chemically active mud liquid with pH 8.2. Due to gravity, the mud liquid settles at the interface of the mud and the aluminum surface while forming locally scattered patches of liquid films. Once the mud liquid dries, adhesion work to remove the dry mud increases significantly. The mud liquid gives rise to the formation of pinholes and local pit sites on the aluminum surface. Morphological changes due to pit sites and residues of the dry mud on the aluminum surface lower the surface reflection after the removal of the dry mud from the surface. The characteristics of the aluminum surface can address the dust/mud-related limitations of reflective surfaces and may have implications for the reductions in the efficiencies of solar concentrated power systems. PMID:28378798

The Rome trough and evolution of the Iapetean margin

DOE Office of Scientific and Technical Information (OSTI.GOV)

Walker, D.; Hamilton-Smith, T.; Drahovzal, J.A.

1991-08-01

Recent structural mapping of the Rome trough suggests a complex structure very different from the symmetrical and laterally continuous graben commonly depicted. Early and Middle Cambrian extension in the Rome trough of eastern Kentucky and adjacent areas resulted in a series of alternately facing half-grabens with variable displacement. These half-grabens are bounded by southwest-northeast-trending normal faults (e.g., Kentucky River and Warfield faults), which are laterally continuous only on the order to tens of kilometers. The Rome trough is laterally segmented by north-south-trending faults (e.g., Lexington fault) commonly expressed as flexures in younger rocks (e.g., Burning Springs anticline and Floyd Countymore » channel). Many of these north-south-trending faults have significant left-lateral displacement, and probably represent reactivated thrust faults of the Grenville tectonic front. The Rome trough and the associated Mississippi Valley, Rough Creek, and Birmingham fault systems were initiated during an Early Cambrian shift in sea-floor spreading from the Blue Ridge-Pine Mountain rift to the Ouachita rift along the Alabama-Oklahoma transform fault. These fault systems have been proposed as having originated from extensional stress propagated northward from the Ouachita rift across the transform fault. In the alternate model proposed here, faulting was brittle, extensional failure resulting form subsidence and flexure of the continental margin to the east. Following initiation of sea-floor spreading at the Blue Ridge-Pine Mountain rift in the latest Proterozoic, margin subsidence in the presence of the Alabama-Oklahoma transform boundary and the inherited Grenville tectonic front resulted in this interior cratonic fault system.« less

Evidence for Recent Liquid Water on Mars: Gullies in Sirenum Fossae Trough

NASA Technical Reports Server (NTRS)

2000-01-01

This mosaic of two Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) images shows about 20 different gullies coming down the south-facing wall of a trough in the Sirenum Fossae/Gorgonum Chaos region of the martian southern hemisphere. Each channel and its associated fan--or apron--of debris appears to have started just below the same hard, resistant layer of bedrock located approximately 100 meters (about 325 feet) below the top of the trough wall. The layer beneath this hard, resistant bedrock is interpreted to be permeable, which allows ground water to percolate through it and--at the location of this trough--seep out onto the martian surface. The channels and aprons only occur on the south-facing slope of this valley created by faults on each side of the trough. The depression is approximately 1.4 km (0.9 mi) across.

The mosaic was constructed from two pictures taken on September 16, 1999, and May 1, 2000. The black line is a gap between the two images that was not covered by MOC. The scene covers an area approximately 5.5 kilometers (3.4 miles) wide by 4.9 km (3.0 mi) high. Sunlight illuminates the area from the upper left. The image is located near 38.5oS, 171.3oW. MOC high resolution images are taken black-and-white (grayscale); the color seen here has been synthesized from the colors of Mars observed by the MOC wide angle cameras and by the Viking Orbiters in the late 1970s.

Impact of Pharmacy Practice Model Expansion on Pharmacokinetic Services: Optimization of Vancomycin Dosing and Improved Patient Safety.

PubMed

Han, Zhe; Pettit, Natasha N; Landon, Emily M; Brielmaier, Benjamin D

2017-04-01

Background: The impact of pharmacy interventions on optimizing vancomycin therapy has been described, however interventions vary among studies and the most optimal pharmacy practice model (PPM) for pharmacokinetic (PK) services has not been established. Objective: The purpose of this study is to demonstrate the value of 24 hours a day, 7 days a week (24/7) PK services. Methods: New PK services were implemented in 2 phases with institutional PPM expansion. Phase 1 included universal monitoring by pharmacists with recommendations made to prescribers during business hours. Phase 2 expanded clinical pharmacists' coverage to 24/7 and provided an optional 24/7 pharmacist-managed PK consult service. We compared vancomycin therapeutic trough attainment, dosing, and clinical and safety outcomes between phases 1 and 2 in adult inpatients receiving therapeutic intravenous vancomycin. Results. One hundred and fifty patients were included in each phase. Phase 2 had a greater proportion of vancomycin courses with therapeutic initial trough concentrations (27.5% vs 46.1%; p = 0.002), higher initial trough concentrations (10.9 mcg/mL vs 16.4 mcg/mL; p < 0.001), and optimized initial vancomycin dosing (13.5 mg/kg vs 16.2 mg/kg; p < 0.001). Phase 2 also saw significant reduction in the incidence of vancomycin-associated nephrotoxicity (21.1% vs 11.7%; p = 0.038). Dose optimization and improvement in initial target trough attainment were most notable among intensive care unit (ICU) patients. Conclusions. Our study demonstrated that 24/7 PK services implemented with institutional PPM expansion optimized vancomycin target trough attainment and improved patient safety.

Synoptic patterns leading to hailstorm in Chaharmahal and Bakhtiari province, Iran

NASA Astrophysics Data System (ADS)

Salahi, Bromand; Nohegar, Ahmad; Behrouzi, Mahmoud; Aalijahan, Mehdi

2018-03-01

The purpose of this study was to extract the synoptic patterns of 500 mb geopotential height and the sea level pressure leading to form hail in Chaharmahal and Bakhtiari province, Iran. To this end, at first, we explored hail occurrence in different areas of the province under investigation. Then, using sea level pressure and 500 mb geopotential height data, the patterns of hail occurrence were investigated through hierarchical clustering and Ward's method. The level of 500 mb patterns resulting in hail formation in the area include: (1) settlement of a cut-off low pressure blocking in Turkey and Iran's position in downstream of trough and injection of humidity coming from the Red Sea; (2) settlement of low ridge in northern Europe and Iran lying in downstream of the trough and injection of humidity of the Mediterranean Sea; (3) settlement of a cut-off low pressure in east of Europe and Iran lying in downstream of the trough; and (4) settlement of a deep trough in the Mediterranean Sea, formation of an omega-shaped blocking in Northern Europe and Iran lying in downstream of the trough. At sea level, the following patterns have caused hail formation in Chaharmahal and Bakhtiari province: (1) settlement of low pressure in Iran and Russia accompanying high pressure in Taklimakan Desert and east of Europe; (2) settlement of low pressure in Iran and high pressure in Egypt, northern Europe, and Taklimakan Desert; and (3) settlement of low pressure in Iran, Saudi Arabia and south of Italy and high pressure in Egypt and Siberia.

Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids.

PubMed

Mourad, Michel; Mourad, Georges; Wallemacq, Pierre; Garrigue, Valérie; Van Bellingen, Christophe; Van Kerckhove, Valérie; De Meyer, Martine; Malaise, Jacques; Eddour, Djamila Chaib; Lison, Dominique; Squifflet, Jean Paul; Haufroid, Vincent

2005-10-15

CYP3A5 and MDR1 polymorphisms have been shown to influence tacrolimus blood concentrations and dose requirements. The aim is to determine whether these polymorphisms also affect sirolimus trough concentrations and dose requirements after kidney transplantation. Eighty-five renal transplant recipients receiving sirolimus were included. Twenty-four were treated with a combined sirolimus-tacrolimus regimen. Eighty-one patients received steroids. Sirolimus and tacrolimus were adjusted to a target therapeutic window. CYP3A5 (intron 3) and MDR1 (exons 12, 21, 26) genotypes were correlated to the adjusted trough concentrations and dose requirements for both sirolimus and tacrolimus. There were no significant correlation between adjusted sirolimus trough concentrations or dose requirements and genetic polymorphisms. In a multiple regression model, adjusted-prednisone dose was involved with a positive or negative effect when considering sirolimus dose requirements or adjusted concentrations, respectively. In the subgroup of patients treated by tacrolimus and sirolimus, adjusted tacrolimus doses were higher in patients carrying at least one CYP3A5 *1 allele (median 0.083 vs. 0.035 mg/kg for CYP3A5*3/*3 patients, P<0.05). Adjusted-prednisolone dose and CYP3A5 polymorphism explained up to 61% of the variability in tacrolimus dose requirements. Unlike tacrolimus, sirolimus adjusted trough concentrations and dose requirements seem not affected by CYP3A5 and MDR1 polymorphisms. Adjusted-prednisone dose has a significant impact on tacrolimus and sirolimus dose requirements.

Detailed partial load investigation of a thermal energy storage concept for solar thermal power plants with direct steam generation

NASA Astrophysics Data System (ADS)

Seitz, M.; Hübner, S.; Johnson, M.

2016-05-01

Direct steam generation enables the implementation of a higher steam temperature for parabolic trough concentrated solar power plants. This leads to much better cycle efficiencies and lower electricity generating costs. For a flexible and more economic operation of such a power plant, it is necessary to develop thermal energy storage systems for the extension of the production time of the power plant. In the case of steam as the heat transfer fluid, it is important to use a storage material that uses latent heat for the storage process. This leads to a minimum of exergy losses during the storage process. In the case of a concentrating solar power plant, superheated steam is needed during the discharging process. This steam cannot be superheated by the latent heat storage system. Therefore, a sensible molten salt storage system is used for this task. In contrast to the state-of-the-art thermal energy storages within the concentrating solar power area of application, a storage system for a direct steam generation plant consists of a latent and a sensible storage part. Thus far, no partial load behaviors of sensible and latent heat storage systems have been analyzed in detail. In this work, an optimized fin structure was developed in order to minimize the costs of the latent heat storage. A complete system simulation of the power plant process, including the solar field, power block and sensible and latent heat energy storage calculates the interaction between the solar field, the power block and the thermal energy storage system.

Determining the Nature of Late Gunn–Peterson Troughs with Galaxy Surveys

NASA Astrophysics Data System (ADS)

Davies, Frederick B.; Becker, George D.; Furlanetto, Steven R.

2018-06-01

Recent observations have discovered long (up to ∼110 Mpc/h), opaque Gunn–Peterson troughs in the z ∼ 5.5 Lyα forest, which are challenging to explain with conventional models of the post-reionization intergalactic medium. Here, we demonstrate that observations of the galaxy populations in the vicinity of the deepest troughs can distinguish two competing models for these features: deep voids where the ionizing background is weak due to fluctuations in the mean free path of ionizing photons would show a deficit of galaxies, while residual temperature variations from extended, inhomogeneous reionization would show an overdensity of galaxies. We use large (∼550 Mpc/h) semi-numerical simulations of these competing explanations to predict the galaxy populations in the largest of the known troughs at z ∼ 5.7. We quantify the strong correlation of Lyα effective optical depth and galaxy surface density in both models, and estimate the degree to which realistic surveys can measure such a correlation. While a spectroscopic galaxy survey is ideal, we also show that a relatively inexpensive narrowband survey of Lyα-emitting galaxies is ∼90% likely to distinguish between the competing models.

Amazonian volcanism inside Valles Marineris on Mars

NASA Astrophysics Data System (ADS)

Brož, Petr; Hauber, Ernst; Wray, James J.; Michael, Gregory

2017-09-01

The giant trough system of Valles Marineris is one of the most spectacular landforms on Mars, yet its origin is still unclear. Although often referred to as a rift, it also shows some characteristics that are indicative of collapse processes. For decades, one of the major open questions was whether volcanism was active inside the Valles Marineris. Here we present evidence for a volcanic field on the floor of the deepest trough of Valles Marineris, Coprates Chasma. More than 130 individual edifices resemble scoria and tuff cones, and are associated with units that are interpreted as lava flows. Crater counts indicate that the volcanic field was emplaced sometime between ∼0.4 Ga and ∼0.2 Ga. The spatial distribution of the cones displays a control by trough-parallel subsurface structures, suggesting magma ascent in feeder dikes along trough-bounding normal faults. Spectral data reveal an opaline-silica-rich unit associated with at least one of the cones, indicative of hydrothermal processes. Our results point to magma-water interaction, an environment of astrobiological interest, perhaps associated with late-stage activity in the evolution of Valles Marineris, and suggest that the floor of Coprates Chasma is promising target for the in situ exploration of Mars.

Archimede solar energy molten salt parabolic trough demo plant: Improvements and second year of operation

NASA Astrophysics Data System (ADS)

Maccari, Augusto; Donnola, Sandro; Matino, Francesca; Tamano, Shiro

2016-05-01

Since July 2013, the first stand-alone Molten Salt Parabolic Trough (MSPT) demo plant, which was built in collaboration with Archimede Solar Energy and Chiyoda Corporation, is in operation, located adjacent to the Archimede Solar Energy (ASE) manufacturing plant in Massa Martana (Italy). During the two year's operating time frame, the management of the demo plant has shown that MSPT technology is a suitable and reliable option. Several O&M procedures and tests have been performed, as Heat Loss and Minimum Flow Test, with remarkable results confirming that this technology is ready to be extended to standard size CSP plant, if the plant design takes into account molten salt peculiarities. Additionally, the plant has been equipped on fall 2014 with a Steam Generator system by Chiyoda Corporation, in order to test even this important MSPT plant subsystem and to extend the solar field active time, overcoming the previous lack of an adequate thermal load. Here, a description of the plant improvements and the overall plant operation figures will be presented.

Dense Ocean Floor Network for Earthquakes and Tsunamis; DONET/ DONET2, Part2 -Development and data application for the mega thrust earthquakes around the Nankai trough-

NASA Astrophysics Data System (ADS)

Kaneda, Y.; Kawaguchi, K.; Araki, E.; Matsumoto, H.; Nakamura, T.; Nakano, M.; Kamiya, S.; Ariyoshi, K.; Baba, T.; Ohori, M.; Hori, T.; Takahashi, N.; Kaneko, S.; Donet Research; Development Group

2010-12-01

Yoshiyuki Kaneda Katsuyoshi Kawaguchi*, Eiichiro Araki*, Shou Kaneko*, Hiroyuki Matsumoto*, Takeshi Nakamura*, Masaru Nakano*, Shinichirou Kamiya*, Keisuke Ariyoshi*, Toshitaka Baba*, Michihiro Ohori*, Narumi Takakahashi*, and Takane Hori** * Earthquake and Tsunami Research Project for Disaster Prevention, Leading Project , Japan Agency for Marine-Earth Science and Technology (JAMSTEC) **Institute for Research on Earth Evolution, Japan Agency for Marine-Earth Science and Technology (JAMSTEC) DONET (Dense Ocean Floor Network for Earthquakes and Tsunamis) is the real time monitoring system of the Tonankai seismogenic zones around the Nankai trough southwestern Japan. We were starting to develop DONET to perform real time monitoring of crustal activities over there and the advanced early warning system. DONET will provide important and useful data to understand the Nankai trough maga thrust earthquake seismogenic zones and to improve the accuracy of the earthquake recurrence cycle simulation. Details of DONET concept are as follows. 1) Redundancy, Extendable function and advanced maintenance system using the looped cable system, junction boxes and the ROV/AUV. DONET has 20 observatories and incorporated in a double land stations concept. Also, we are developed ROV for the 10km cable extensions and heavy weight operations. 2) Multi kinds of sensors to observe broad band phenomena such as long period tremors, very low frequency earthquakes and strong motions of mega thrust earthquakes over M8: Therefore, sensors such as a broadband seismometer, an accelerometer, a hydrophone, a precise pressure gauge, a differential pressure gauge and a thermometer are equipped with each observatory in DONET. 3) For speedy detections, evaluations and notifications of earthquakes and tsunamis: DONET system will be deployed around the Tonankai seismogenic zone. 4) Provide data of ocean floor crustal deformations derived from pressure sensors: Simultaneously, the development of data assimilation method using DONET data is very important to improve the recurrence cycle simulation model. 5) Understanding of the interaction between the crust and upper mantle around the Nankai trough subduction zone. We will deploy DONET not only in the Tonankai seismogenic zone but also DONET2 with high voltages in the Nankai seismogenic zone western the Nankai trough: The total system will be deployed to understand the seismic linkage between the Tonankai and Nankai earthquakes: Using DONET and DONET2 data, we will be able to observe the crustal activities and before and after slips at the Tonankai earthquake and Nankai earthquake. And we will improve the recurrence cycle simulation model by the advanced data assimilation method. Actually, we constructed one observatory in DONET and observed some earthquakes and tsunamis. We will introduce details of DONET/DONET2 and some observed data.

Stratigraphic framework of Cambrian and Ordovician rocks in the central Appalachian Basin from Medina County, Ohio, through southwestern and south-central Pennsylvania to Hampshire County, West Virginia

USGS Publications Warehouse

Ryder, Robert T.; Harris, Anita G.; Repetski, John E.; revised and digitized by Crangle, Robert D.

2003-01-01

A 275-mi-long restored stratigraphic cross section from Medina County, Ohio, through southwestern and south-central Pennsylvania to Hampshire County, W. Va., provides new details on Cambrian and Ordovician stratigraphy in the central Appalachian basin and the structure of underlying Precambrian basement rocks. From west to east, the major structural elements of the block-faulted basement in this section are (1) the relatively stable, slightly extended craton, which includes the Wooster arch, (2) the fault-controlled Ohio-West Virginia hinge zone, which separates the craton from the adjoining Rome trough, (3) the Rome trough, which consists of an east-facing asymmetric graben and an overlying sag basin, and (4) a positive fault block, named here the South-central Pennsylvania arch, which borders the eastern margin of the graben part of the Rome trough. Pre-Middle Ordovician structural relief on Precambrian basement rocks across the down-to-the-west normal fault that separates the Rome trough and the adjoining South-central Pennsylvania arch amounted to between 6,000 and 7,000 ft. The restored cross section shows eastward thickening of the Cambrian and Ordovician sequence from about 3,000 ft near the crest of the Wooster arch at the western end of the section to about 5,150 ft at the Ohio-West Virginia hinge zone adjoining the western margin of the Rome trough to about 19,800 ft near the depositional axis of the Rome trough. East of the Rome trough, at the adjoining western edge of the South-central Pennsylvania arch, the Cambrian and Ordovician sequence thins abruptly to about 13,500 ft and then thins gradually eastward across the arch to about 12,700 ft near the Allegheny structural front and to about 10,150 ft at the eastern end of the restored section. In general, the Cambrian and Ordovician sequence along this section consists of four major lithofacies that are predominantly shallow marine to peritidal in origin. In ascending stratigraphic order, the lithofacies are identified by the following descriptive names: (1) sandstone, shale, limestone, and dolomite unit, (2) dolomite and sandstone unit, (3) limestone and black shale unit, and (4) shale and sandstone unit. Each of these units and their associated subunits thicken from west to east across the restored section to a maximum near the depositional axis of the Rome trough and then thin eastward to the end of the section. The sandstone, shale, limestone, and dolomite unit is largely confined to the asymmetric graben that marks the initial phase of the Rome trough. This unit is Early and Middle Cambrian in age and consists, in ascending order, of a basal sandstone unit (undrilled but probably present), the Tomstown Dolomite (undrilled but probably present), the Waynesboro Formation, and the Pleasant Hill Limestone and its equivalent lower one-third of the Elbrook Formation at the eastern end of the section. The dolomite and sandstone unit forms the core of the Cambrian and Ordovician sequence. In the Rome trough and on the adjoining South-central Pennsylvania arch, this unit consists, in ascending order, of the Middle and Upper Cambrian Warrior Formation and the equivalent upper two-thirds of the Elbrook Formation at the eastern end of the section, the Upper Cambrian Gatesburg Formation, and the Lower Ordovician and Middle Ordovician (Whiterockian and Chazyan) Beekmantown Group. West of the Ohio-West Virginia hinge zone, the dolomite and sandstone unit consists, in ascending order, of the Conasauga Formation of Janssens (1973), the Krysik sandstone of driller's usage, the B zone of Calvert (1964), the Knox Dolomite and the associated Rose Run Sandstone Member, and the Wells Creek Formation. The widespread Knox unconformity is located at the base of the Wells Creek Formation and at or near the top of the adjoining Beekmantown Group, except near the depositional axis of the Rome trough, where the unconformity seems to be absent. The limestone and black shale unit i

Down hole transmission system

DOEpatents

Hall, David R [Provo, UT; Hall, Jr., H. Tracy

2007-07-24

A transmission system in a downhole component comprises a data transmission element in both ends of the downhole component. Each data transmission element houses an electrically conducting coil in a MCEI circular trough. The electrically conducting coil comprises at least two generally fractional loops. In the preferred embodiment, the transmission elements are connected by an electrical conductor. Preferably, the electrical conductor is a coaxial cable. Preferably, the MCEI trough comprises ferrite. In the preferred embodiment, the fractional loops are connected by a connecting cable. In one aspect of the present invention, the connecting cable is a pair of twisted wires. In one embodiment the connecting cable is a shielded pair of twisted wires. In another aspect of the present invention, the connecting cable is a coaxial cable. The connecting cable may be disposed outside of the MCEI circular trough.

Contrasting modes of rifting: The Benue Trough and Cameroon Volcanic Line, West Africa

NASA Astrophysics Data System (ADS)

Okereke, C. S.

1988-08-01

The Benue trough of west Africa is commonly believed to be a rift feature that originated in the Cretaceous at about the time that Africa and South America began to separate. Bouguer gravity and available geological data in the trough indicate that its formation was probably the result of regional horizontal stresses in the lithosphere, causing crustal extension and surface subsidence. By contrast, the data for the adjoining Cameroon volcanic line suggests that the associated tensional stresses relate to mantle upwarp causing thinning of the lithosphere and regional crustal uplift similar to that associated with the Kenya rift. Thus the association of passive and active rifts seen in the Afro-Arabia rift system is also a feature of the Cretaceous rift system in west Africa.

Ancient geodynamics and global-scale hydrology on Mars.

PubMed

Phillips, R J; Zuber, M T; Solomon, S C; Golombek, M P; Jakosky, B M; Banerdt, W B; Smith, D E; Williams, R M; Hynek, B M; Aharonson, O; Hauck , S A

2001-03-30

Loading of the lithosphere of Mars by the Tharsis rise explains much of the global shape and long-wavelength gravity field of the planet, including a ring of negative gravity anomalies and a topographic trough around Tharsis, as well as gravity anomaly and topographic highs centered in Arabia Terra and extending northward toward Utopia. The Tharsis-induced trough and antipodal high were largely in place by the end of the Noachian Epoch and exerted control on the location and orientation of valley networks. The release of carbon dioxide and water accompanying the emplacement of approximately 3 x 10(8) cubic kilometers of Tharsis magmas may have sustained a warmer climate than at present, enabling the formation of ancient valley networks and fluvial landscape denudation in and adjacent to the large-scale trough.

Crustal Structure in the Southern Rockall Trough from Satellite Gravity Data: Evidence for Sea-floor Spreading

NASA Astrophysics Data System (ADS)

Chappell, A.; Kusznir, N. J.

2005-05-01

The southern Rockall Trough south of 57 N has previously been interpreted as either an intra-continental rift floored with highly extended continental crust, or a failed oceanic rift formed by Cretaceous sea floor spreading. Satellite gravity, bathymetry data and seismic estimates of sediment thickness are used to derive crustal basement thickness for the southern Rockall Trough and adjacent regions using a gravity inversion method incorporating a correction for the large negative thermal gravity component present in oceanic and stretched continental lithosphere. The marine Bouguer anomaly, derived from satellite free air gravity (Sandwell & Smith 1997) and Gebco 2003 bathymetry data, is inverted using the method of Oldenberg (1974), incorporating an iteratively applied thermal anomaly correction, to give Moho depth. For oceanic crust the thermal anomaly correction is calculated using isochron ages (Muller et al. 1997) and for continental crust from the beta stretching factors resulting from gravity derived crustal basement thickness and an assumed rift age. When sediment thickness and volcanic addition are assumed to be zero, the resulting upper bound of crustal thickness from the gravity inversion is as little as 10 km in the southern Rockall Trough. A segmented axial thickening of the crust at the centre of the Rockall Trough is predicted, between the Barra volcanic ridge and the Anton Dohrn seamount and is interpreted as having a volcanic origin. Inclusion of a sediment thickness correction in the gravity inversion further reduces predicted crustal thickness. A pseudo-sediment-thickness map has been constructed from the available wide-angle data and incorporated in the gravity inversion. The addition of up to 5.5 km of sediment in the gravity inversion reduces the upper bound of crustal thickness to less than 3 km in some locations. The segmented axial thickening and thin crust shown by the gravity inversion, the lack of intra-basinal faulting, and the volcanic origin for the axis shown by normal incidence seismic data, are consistent with a sea-floor spreading origin for the southern Rockall Trough and not formation by intra-continental rifting. We investigate the formation of the southern Rockall Trough using SfMargin, a new model of continental lithosphere thinning leading to continental breakup and sea-floor spreading initiation. Comparisons of the geometry of the southern Rockall Trough predicted by SfMargin with that observed are consistent with a short period (20Ma) of slow Cretaceous sea-floor spreading, followed by thermal subsidence to present day. This work forms part of the NERC Margins iSIMM project. iSIMM investigators are from Liverpool and Cambridge Universities, Badley Geoscience & Schlumberger Cambridge Research supported by the NERC, the DTI, Agip UK, BP, Amerada Hess Ltd, Anadarko, ConocoPhillips, Shell, Statoil and WesternGeco. The iSIMM team comprises NJ Kusznir, RS White, AM Roberts, PAF Christie, A Chappell, J Eccles, R Fletcher, D Healy, N Hurst, ZC Lunnon, CJ Parkin, AW Roberts, LK Smith, V Tymms & R Spitzer.

Reliability of power profiles measured on NIMO TR1504 (Lambda-X) and effects of lens decentration for single vision, bifocal and multifocal contact lenses.

PubMed

Kim, Eon; Bakaraju, Ravi C; Ehrmann, Klaus

2016-01-01

To evaluate the repeatability of power profiles measured on NIMO TR1504 (Lambda-X, Belgium) and investigate the effects of lens decentration on the power profiles for single vision (SV), bifocal (BF) and multifocal (MF) contact lenses. Accuracy of the sphere power was evaluated using single vision BK-7 calibration glass lenses of six minus and six plus powers. Three SV and four BF/MF contact lenses - three lenses each, were measured five times to calculate the coefficients of repeatability (COR) of the instrument. The COR was computed for each chord position, lens design, prescription power and operator. One lens from each type was measured with a deliberate decentration up to ±0.5mm in 0.1mm steps. For all lenses, the COR varied across different regions of the half-chord position. In general, SV lenses showed lower COR compared to the BF/MF group lenses. There were no noticeable trends of COR between prescription powers for SV and BF/MF lenses. The shape of the power profiles was not affected when lenses were deliberately decentered for all SV and PureVision MF lenses. However, for Acuvue BF lenses, the peak to trough amplitude of the power profiles flattened up to 1.00D. The COR across the half-chord of the optic zone diameter was mostly within clinical relevance except for the central 0.5mm half-chord position. COR were dependent on the lens type, whereby BF/MF group produced higher COR than SV lenses. The effects of deliberate decentration on the shape of power profiles were pronounced for lenses where the profiles had sharp transitions of power. Copyright © 2015 Spanish General Council of Optometry. Published by Elsevier Espana. All rights reserved.

Western Ross Sea continental slope gravity currents

NASA Astrophysics Data System (ADS)

Gordon, Arnold L.; Orsi, Alejandro H.; Muench, Robin; Huber, Bruce A.; Zambianchi, Enrico; Visbeck, Martin

2009-06-01

Antarctic Bottom Water of the world ocean is derived from dense Shelf Water that is carried downslope by gravity currents at specific sites along the Antarctic margins. Data gathered by the AnSlope and CLIMA programs reveal the presence of energetic gravity currents that are formed over the western continental slope of the Ross Sea when High Salinity Shelf Water exits the shelf through Drygalski Trough. Joides Trough, immediately to the east, offers an additional escape route for less saline Shelf Water, while the Glomar Challenger Trough still farther east is a major pathway for export of the once supercooled low-salinity Ice Shelf Water that forms under the Ross Ice Shelf. The Drygalski Trough gravity currents increase in thickness from ˜100 to ˜400 m on proceeding downslope from ˜600 m (the shelf break) to 1200 m (upper slope) sea floor depth, while turning sharply to the west in response to the Coriolis force during their descent. The mean current pathway trends ˜35° downslope from isobaths. Benthic-layer current and thickness are correlated with the bottom water salinity, which exerts the primary control over the benthic-layer density. A 1-year time series of bottom-water current and hydrographic properties obtained on the slope near the 1000 m isobath indicates episodic pulses of Shelf Water export through Drygalski Trough. These cold (<-1 °C), salty (>34.75) pulses correlate with strong downslope bottom flow. Extreme examples occurred during austral summer/fall 2003, comprising concentrated High Salinity Shelf Water (-1.9 °C; 34.79) and approaching 1.5 m s -1 at descent angles as large as ˜60° relative to the isobaths. Such events were most common during November-May, consistent with a northward shift in position of the dense Shelf Water during austral summer. The coldest, saltiest bottom water was measured from mid-April to mid-May 2003. The summer/fall export of High Salinity Shelf Water observed in 2004 was less than that seen in 2003. This difference, if real, may reflect the influence of the large iceberg C-19 over Drygalski Trough until its departure in mid-May 2003, when there was a marked decrease in the coldest, saltiest gravity current adjacent to Drygalski Trough. Northward transport of cold, saline, recently ventilated Antarctic Bottom Water observed in March 2004 off Cape Adare was ˜1.7 Sv, including ˜0.4 Sv of High Salinity Shelf Water.

Poultry farm hygiene: microbiological quality assessment of drinking water used in layer chickens managed under the battery cage and deep litter systems at three poultry farms in southwestern Nigeria.

PubMed

Folorunso, O R; Kayode, Sule; Onibon, V O

2014-01-01

Water troughs from deep litter and caged chicken water troughs (drinkers) fixed to each of the different 3-tier cages containing layer chickens in Farms A, B and C were subjected to a 7-day study which involved the monitoring of poultry farm hygiene. Drinkers were washed before filling with water on Day 1. For Days 3, 5 and 7 water was served without prior washing. The occurrence and characterization of the bacteria isolates were investigated and data obtained were analyzed and compared. For the bacterial count on Day 1, for layer chickens on cage system, no significant differences (p > 0.05) among the farms and between the farms tier interactions. On Day 3, no significant difference (p > 0.05) among the parameters. On Day 5, there was significant difference (p<0.05) among the farms and on Day 7, there was high significant difference (p < 0.01) among the farms. On Days 5 and 7, there were no significant differences (p>0.05) among the tiers nor between the interactions of the farms and tiers. The bacterial count in water troughs of layer chickens in deep litter system, on Day 1, had no significant differences (p > 0.05) between the farms, water troughs and their interactions. On Day 3, no significant difference (p > 0.05) among the parameters. On Days 5 and 7, there were significant difference (p<0.05) and a high significant difference (p < 0.01) between the farms respectively. On Days 5 and 7, no significant differences between the water troughs and between the interaction of the farms and the water troughs. Farm A isolates contained Staphylococcus aureus, Proteus vulgaris, Streptococcus faecalis, Escherichia coli, Staphylococcus epidermis, Klebsiella sp., Salmonella sp., Bacillus subtilis, Lactobacillus salivarius and Corynebacterium sp. Farm B had Staphylococcus aureus, S. epidermis, Bacillus subtilis, Corynebacterium sp., Escherichia coli, Streptococcus faecalis and Klebsiella sp. while for Farm C, apart from the prevalent bacteria isolates obtained in Farms A and B, additional 2 bacterial isolates, Lactobacillus salivarius and Pseudomonas aeuriginosa were found. In conclusion, water troughs when cleaned on daily basis carry minimum bacterial load. Those left for 3, 5 and 7 days uncleaned had progressively high bacterial loads, suggesting that the flock of birds and the consumers of the eggs and meat from the chickens are at risk of bacterial infection unless strict farm hygiene is ensured through regular monitoring.

Probabilistic Tsunami Hazard Assessment along Nankai Trough (2) a comprehensive assessment including a variety of earthquake source areas other than those that the Earthquake Research Committee, Japanese government (2013) showed

NASA Astrophysics Data System (ADS)

Hirata, K.; Fujiwara, H.; Nakamura, H.; Osada, M.; Morikawa, N.; Kawai, S.; Ohsumi, T.; Aoi, S.; Yamamoto, N.; Matsuyama, H.; Toyama, N.; Kito, T.; Murashima, Y.; Murata, Y.; Inoue, T.; Saito, R.; Takayama, J.; Akiyama, S.; Korenaga, M.; Abe, Y.; Hashimoto, N.

2016-12-01

For the forthcoming Nankai earthquake with M8 to M9 class, the Earthquake Research Committee(ERC)/Headquarters for Earthquake Research Promotion, Japanese government (2013) showed 15 examples of earthquake source areas (ESAs) as possible combinations of 18 sub-regions (6 segments along trough and 3 segments normal to trough) and assessed the occurrence probability within the next 30 years (from Jan. 1, 2013) was 60% to 70%. Hirata et al.(2015, AGU) presented Probabilistic Tsunami Hazard Assessment (PTHA) along Nankai Trough in the case where diversity of the next event's ESA is modeled by only the 15 ESAs. In this study, we newly set 70 ESAs in addition of the previous 15 ESAs so that total of 85 ESAs are considered. By producing tens of faults models, with various slip distribution patterns, for each of 85 ESAs, we obtain 2500 fault models in addition of previous 1400 fault models so that total of 3900 fault models are considered to model the diversity of the next Nankai earthquake rupture (Toyama et al.,2015, JpGU). For PTHA, the occurrence probability of the next Nankai earthquake is distributed to possible 3900 fault models in the viewpoint of similarity to the 15 ESAs' extents (Abe et al.,2015, JpGU). A major concept of the occurrence probability distribution is; (i) earthquakes rupturing on any of 15 ESAs that ERC(2013) showed most likely occur, (ii) earthquakes rupturing on any of ESAs whose along-trench extent is the same as any of 15 ESAs but trough-normal extent differs from it second likely occur, (iii) earthquakes rupturing on any of ESAs whose both of along-trough and trough-normal extents differ from any of 15 ESAs rarely occur. Procedures for tsunami simulation and probabilistic tsunami hazard synthesis are the same as Hirata et al (2015). A tsunami hazard map, synthesized under an assumption that the Nankai earthquakes can be modeled as a renewal process based on BPT distribution with a mean recurrence interval of 88.2 years (ERC, 2013) and an aperiodicity of 0.22, as the median of the values (0.20 to 0.24)that ERC (2013) recommended, suggests that several coastal segments along the southwest coast of Shikoku Island, the southeast coast of Kii Peninsula, and the west coast of Izu Peninsula show over 26 % in exceedance probability that maximum water rise exceeds 10 meters at any coastal point within the next 30 years.

Characterization of inappetent sheep in a feedlot using radio-tracking technology.

PubMed

Barnes, Anne L; Wickham, Sarah L; Admiraal, Ryan; Miller, David W; Collins, Teresa; Stockman, Catherine; Fleming, Patricia A

2018-04-03

The feeding and drinking behaviours of sheep were monitored using RFID technology at a commercial pre-embarkation feedlot in Western Australia with the aim of characterizing feeding and drinking patterns of inappetent sheep that might allow them to be treated. Feeding and drinking behaviours of sheep were compared with their survival and change in body condition. Patterns of number of visits and the time spent at feed and water troughs were analyzed for a total of 8,206 sheep, representing four consignments that were monitored for a range of 6-31 d. Data for feeding and drinking behaviours were compared for the first 6 d. For animals that were alive at exit, 18.9% of sheep attended the feed trough for less than 0.25 h d-1 (15 min per day) on day 1; this decreased to only 2.4% of sheep by day 6. Of the sheep monitored, 0.93% died (n = 76); Salmonella spp. infection was the leading cause of death (n = 40; 52.6% of all deaths) across all months and was accompanied with inanition. There was marked variability in the average time spent at the feed trough for sheep that died eventually from salmonella/inanition (contributing to the lack of statistical difference in time spent at feed trough between sheep dying from different causes; P = 0.056). Over half (55%) of the animals diagnosed with salmonella/inanition spent an average of less than 0.50 h d-1 (30 min per day) and 45% less than 0.25 h d-1 at the feed trough. There was a negative correlation (r) in time spent at the feed trough overtime for individual sheep that died from salmonella/inanition, indicating that these individuals went off their feed. This pattern was not evident for animals that died from other causes (significant difference in r values between five categories of cause of death; P = 0.040). Characterization of feeding behaviour of sheep that died from salmonella/inanition therefore appears to require more than simply monitoring daily intake. There was no difference in time spent at water troughs between sheep that died or were alive at exit (average 0.30 ± 0.23 h d-1). This study reveals that the patterns of feeding and drinking behaviours during pre-embarkation feedlotting do not readily allow identification of animals that warrant singling out for veterinary care or alternative feed arrangements. This result highlights the need for experienced stockmanship in handling these animals.

Lakes in Valles Marineris

NASA Astrophysics Data System (ADS)

Lucchitta, Baerbel K.

2010-10-01

The paper reviews the evolution of hypotheses of lakes in Valles Marineris through observations made from the time of Mariner and continuing through the Viking, MGS, MO, MEx, and MRO missions. Several pertinent findings from these missions are addressed, including: The morphology and composition of the interior layered deposits (ILD); the question whether ILD are deposited inside the troughs or exhumed from the walls; the possible existence of ancestral basins; the derivation of water; arguments for an origin as aqueous, eolian, or pyroclastic sediments, or sub/ice volcanoes; origin of inclined layers, mounds and moats; and age relations of features within and peripheral to the troughs. A possible scenario begins with the collapse of ice-charged ground into ancestral basins along structural planes of weakness due to Tharsis stresses, about 3.5 Ga ago. The basins rapidly filled with water from ground ice, subterranean aquifers, or nearby valley networks. The water spilled out of the peripheral troughs and flowed across high plateaus into early outflow channels. The ancestral basins then filled with sediments derived from valley networks or from trapped eolian or pyroclastic deposits. Alternatively, volcanoes rose under the water or ice to form tuyas. The water was highly acidic, and sediments may have been deposited directly as evaporites or were later altered to evaporites by the brines or by hydrothermal activity. Percolating fluids produced iron oxide concretions. Similar alteration would have affected the putative volcanoes. Most of the ILD were emplaced early in the troughs' history. Shortly thereafter, more water erupted from the peripheral troughs and formed additional chaos and outflow channels. The ancestral basins were breached by erosion and tectonism, and the through-going Coprates/Ius graben system developed. Major lakes within the Valles Marineris dried up and vigorous wind erosion reduced the friable, evaporite-rich sediments to isolated mounds. Simultaneously, the iron oxide concretions weat hered out to form lag deposits mostly at the base of scarps. During that time, some of the ILD may have become tilted by structural deformation. Alternatively, inclined beds on the mounds may have come from draping by volcanic ash or eolian deposits, or by gravity sliding on the steep, evaporite-charged flanks of the mounds. Inclined layers could be readily explained if the ILD were tuyas. Landslides fell into the newly created voids and occasional sliding persisted throughout most of the troughs' history. Minor volcanic activity continued and may have spewed mafic ash onto the eroded ILD-mound surfaces and onto the trough floors. Eventually, only wind persisted, producing yardangs on the ILD and reworking ash, trapped eolian sediments, and debris eroded from the ILD.

High H2O/Ce of K-rich MORB from Lena Trough and Gakkel Ridge, Arctic Ocean

NASA Astrophysics Data System (ADS)

Snow, J. E.; Feig, S. T.

2014-12-01

Lena Trough in the Arctic ocean is the oblique spreading continuation of Gakkel Ridge through the Fram Strait (eg Snow et al. 2011). Extreme trace element and isotopic compositions seen in Lena Trough basalt appear to be the enriched end member dominating the geochemistry of the Western Volcanic Zone of the Western Gakkel Ridge as traced by Pb isotopes, K2O/TiO2, Ba/Nb and other isotopic, major and trace element indicators of mixing (Nauret et al., 2011). This is in contrast to neighboring Gakkel Ridge which has been spreading for 50-60 million years. Basalts from Lena Trough also show a pure MORB noble gas signature (Nauret et al., 2010) and peridotites show no evidence of ancient components in their Os isotopes (Lassiter, et al., in press). The major and trace element compositions of the basalts, however are very distinct from MORB, being far more potassic than all but a single locality on the SW Indian Ridge. We determined H2O and trace element composiitions of a suite of 17 basalt glasses from the Central Lena Trough (CLT) and the Gakkel Western Volcanic Zone, including many of those previously analyzed by Nauret et al. (2012). The Western Gakkel glasses have high H2O/Ce for MORB (>300) suggesting a water rich source consistent with the idea that the northernmost Atlantic mantle is enriched in water (Michael et al., 1995). They are within the range of Eastern Gakkel host glasses determined by Wanless et al, 2013. The Lena Trough (CLT) glasses are very rich in water for MORB (>1% H2O) and are among the highest H2O/Ce (>400) ever measured in MORB aside from melt inclusions in olivine. Mantle melting dynamics and melt evolution cannot account for the H2O/Ce variations in MORB, as these elements have similar behavior during melting and crustal evolution. Interestingly, the H2O/K2O ratios in the basalts are only around 1. This is because the K2O levels in the CLT glasses are very high as well relative to REE. The absolutely linear relationship between H2O and K2O/TiO2 in Lena and Gakkel basalts shows that water systematics in these rocks are completely governed by source composition, with little or no modification by mantle melting dynamics or crystal fractionation. The geochemical influence of the WVZ enriched mantle source declines with distance from Lena Trough along Gakkel Ridge.

Brimonidine 0.2% vs unoprostone 0.15% both added to timolol maleate 0.5% given twice daily to patients with primary open-angle glaucoma or ocular hypertension.

PubMed

Sharpe, E D; Henry, C J; Mundorf, T K; Day, D G; Stewart, J A; Jenkins, J N; Stewart, W C

2005-01-01

To compare the efficacy and safety of brimonidine 0.2% vs unoprostone 0.15%, both added to timolol maleate 0.5% each given twice daily. In this prospective, multi-centred, double-masked, crossover comparison, patients were randomized to one treatment group for a 6-week treatment period, and then crossed over to the opposite treatment. Measurements were performed at 0800, 1000, 1600, 1800, and 2000 h at baseline and at the end of each treatment period. In all, 33 patients entered this trial and 29 completed. The baseline trough intraocular pressure (IOP) was 23.3+/-2.4 and the diurnal curve IOP was 22.0+/-1.3 mmHg. For the brimonidine and timolol maleate treatment group, the trough IOP was 21.6+/-3.3 and the diurnal curve IOP was 19.8+/-2.1 mmHg, while the timolol and unoprostone treatment showed a trough IOP of 20.9+/-3.8 and a diurnal curve IOP of 19.3+/-2.4 mmHg. There was no significant difference between treatment groups at any time point for the diurnal curve, or in the reduction from baseline (P>0.05). Both treatments failed to statistically reduce the IOP from baseline at 1800 h. There was no difference between treatment groups regarding ocular and systemic unsolicited adverse events, but patients admitted to more dryness (P=0.02) and burning upon instillation (P<0.0001) with unoprostone by survey. Brimonidine 0.2% or unoprostone 0.15% added to timolol maleate 0.5% provide similar efficacy and safety throughout the daytime diurnal curve.

Switching from rivaroxaban to warfarin: an open label pharmacodynamic study in healthy subjects

PubMed Central

Moore, Kenneth Todd; Byra, William; Vaidyanathan, Seema; Natarajan, Jaya; Ariyawansa, Jay; Salih, Hiba; Turner, Kenneth C

2015-01-01

Aims The primary objective was to explore the pharmacodynamic changes during transition from rivaroxaban to warfarin in healthy subjects. Safety, tolerability and pharmacokinetics were assessed as secondary objectives. Methods An open label, non-randomized, sequential two period study. In treatment period 1 (TP1), subjects received rivaroxaban 20 mg once daily (5 days), followed by co-administration with a warfarin loading dose regimen of 5 or 10 mg (for the 10 mg regimen, the dose could be uptitrated to attain target international normalized ratio [INR] ≥2.0) once daily (2–4 days). When trough INR values ≥2.0 were attained, rivaroxaban was discontinued and warfarin treatment continued as monotherapy (INR 2.0–3.0). During treatment period 2, subjects received the same warfarin regimen as in TP1, but without rivaroxaban. Results During co-administration, maximum INR and prothrombin time (PT) values were higher than with rivaroxaban or warfarin monotherapy. The mean maximum effect (Emax) for INR after co-administration was 2.79–4.15 (mean PT Emax 41.0–62.7 s), compared with 1.41–1.74 (mean PT Emax 20.1–25.2 s) for warfarin alone. However, rivaroxaban had the smallest effect on INR at trough rivaroxaban concentrations. Neither rivaroxaban nor warfarin significantly affected maximum plasma concentrations of the other drug. Conclusions The combined pharmacodynamic effects during co-administration of rivaroxaban and warfarin were greater than additive, but the pharmacokinetics of both drugs were unaffected. Co-administration was well tolerated. When transitioning from rivaroxaban to warfarin, INR monitoring during co-administration should be performed at the trough rivaroxaban concentration to minimize the effect of rivaroxaban on INR. PMID:25475601

Body mass index influences infliximab post-infusion levels and correlates with prospective loss of response to the drug in a cohort of inflammatory bowel disease patients under maintenance therapy with Infliximab.

PubMed

Scaldaferri, Franco; D'Ambrosio, Daria; Holleran, Grainne; Poscia, Andrea; Petito, Valentina; Lopetuso, Loris; Graziani, Cristina; Laterza, Lucrezia; Pistone, Maria Teresa; Pecere, Silvia; Currò, Diego; Gaetani, Eleonora; Armuzzi, Alessandro; Papa, Alfredo; Cammarota, Giovanni; Gasbarrini, Antonio

2017-01-01

Infliximab is an effective treatment for inflammatory bowel disease (IBD). Studies differ regarding the influence of body mass index (BMI) on the response to infliximab, with the majority of studies indicating that increased BMI may be associated with a poorer response to Infliximab. However, the pharmacokinetic mechanisms causing this have not yet been reported. Examine the correlation between BMI/immunosuppressant use with clinical response, trough and post-infusion levels of infliximab, tumour necrosis factor-α(TNF-α) and anti-drug antibodies(ATI), and determine if these factors can predict future response. We collected serum from 24 patients receiving Infliximab before and 30 minutes following infusion. Clinical parameters were collected retrospectively and prospectively. ELISA measurements of infliximab, TNF-α and ATI were performed. We confirmed that patients with higher infliximab trough levels have a better response rate and that patients with an elevated BMI display a higher rate of loss of response (20%). Patients with a higher BMI had elevated post-infusion levels of infliximab. Additionally, the ratio of IFX/TNF-α trough levels correlated with clinical response to the following infusion. This study confirms that an elevated BMI is associated with a poorer response to infliximab. For the first time, we describe that a higher BMI correlates with higher post-infusion levels, however this does not correlate with a higher rate of response to the drug, suggesting that circulating drug levels do not correlate with tissue levels. Furthermore, in our small cohort of patients, we identified a possible predictive marker of future response to treatment which may be used to guide dose escalation and predict non-response to infliximab.

Assessment of drug-drug interaction potential between ceritinib and proton pump inhibitors in healthy subjects and in patients with ALK-positive non-small cell lung cancer.

PubMed

Lau, Yvonne Y; Gu, Wen; Lin, Tiffany; Viraswami-Appanna, Kalyanee; Cai, Can; Scott, Jeffrey W; Shi, Michael

2017-06-01

The impact of proton pump inhibitors (PPIs) on the pharmacokinetics (PK) and efficacy of ceritinib was evaluated. A healthy subject drug-drug interaction (DDI) study was conducted to assess the effect of esomeprazole on the PK of a single 750 mg dose of ceritinib. To further investigate the impact of PPIs on the PK and efficacy of ceritinib in ALK-positive cancer patients, two subgroup analyses were performed. Analysis 1 evaluated ceritinib steady-state trough concentration (C trough,ss ) and overall response rate (ORR) by concomitant use of PPIs in patients from the ASCEND-1, -2, and -3 studies; analysis 2 evaluated ceritinib single-dose and steady-state AUC 0-24h and C max by concomitant PPI use in patients from ASCEND-1 using a definition of PPI usage similar to that used in the healthy subject study. In the healthy subject study, co-administration of a single 750 mg dose of ceritinib with esomeprazole 40 mg for 6 days decreased ceritinib AUC 0-∞ by 76% and C max by 79%. However, based on subgroup analysis 1, patients had similar C trough,ss and ORR regardless of concomitant PPI usage. Based on analysis 2, co-administration of a single 750 mg ceritinib dose with PPIs for 6 days in patients suggested less effect on ceritinib exposure than that observed in healthy subjects as AUC 0-24h decreased by 30% and C max decreased by 25%. No clinically meaningful effect on steady-state exposure was observed after daily dosing. Long-term administration of ceritinib with PPIs does not adversely affect the PK and efficacy of ceritinib in ALK-positive cancer patients.

Dabigatran Levels in Elderly Patients with Atrial Fibrillation: First Post-Marketing Experiences.

PubMed

Bolek, Tomáš; Samoš, Matej; Škorňová, Ingrid; Stančiaková, Lucia; Staško, Ján; Galajda, Peter; Kubisz, Peter; Mokáň, Marián

2018-05-08

The number of elderly individuals with non-valvular atrial fibrillation (NV-AF) requiring long-term anticoagulation is rising. The pharmacokinetics of oral anticoagulants in elderly individuals may differ from that for younger patients. The aim of this study was to assess the dabigatran levels in elderly patients with NV-AF. A pilot prospective post-marketing study in patients with NV-AF on dabigatran therapy was performed; we enrolled 21 consecutive elderly patients (aged ≥ 75 years) on a reduced dabigatran regimen (110 mg twice daily) and compared them with 13 younger (≤ 70 years) individuals on reduced dabigatran therapy due to renal impairment and with 16 younger patients on standard dabigatran therapy (150 mg twice daily). Blood samples were taken for the assessment of dabigatran trough and peak levels. Dabigatran levels were measured with the Hemoclot ® Thrombin Inhibitor Assay. There were significant differences in dabigatran trough levels when comparing elderly patients on reduced dabigatran with non-elderly patients on reduced dabigatran (99.3 ± 73.6 vs 51.6 ± 25.6 ng/mL; p < 0.01). Similarly, the detected dabigatran peak levels were significantly higher in elderly patients on reduced dabigatran compared with non-elderly patients on reduced dabigatran (173.4 ± 116.2 vs 116.1 ± 19.1 ng/mL; p < 0.01). No significant differences in dabigatran trough and peak levels were found when comparing elderly patients on reduced dabigatran with non-elderly patients on standard dabigatran therapy. This pilot study demonstrated that elderly patients on reduced dabigatran exhibit significantly higher dabigatran levels than younger individuals on a reduced regimen, and similar levels compared with younger individuals on standard dabigatran.

Daily Patterns of Preschoolers' Objectively Measured Step Counts in Six European Countries: Cross-Sectional Results from the ToyBox-Study.

PubMed

Van Stappen, Vicky; Van Dyck, Delfien; Latomme, Julie; De Bourdeaudhuij, Ilse; Moreno, Luis; Socha, Piotr; Iotova, Violeta; Koletzko, Berthold; Manios, Yannis; Androutsos, Odysseas; Cardon, Greet; De Craemer, Marieke

2018-02-07

This study is part of the ToyBox-study, which is conducted in six European countries (Belgium, Bulgaria, Germany, Greece, Poland and Spain), aiming to develop a cost-effective kindergarten-based, family-involved intervention to prevent overweight and obesity in four- to six-year-old preschool children. In the current study, we aimed to examine and compare preschoolers' step count patterns, across the six European countries. A sample of 3578 preschoolers (mean age: 4.8 ± 0.4) was included. Multilevel analyses were performed to take clustering of measurements into account. Based on the average hourly steps, step count patterns for the six European countries were created for weekdays and weekend days. The step count patterns during weekdays were related to the daily kindergarten schedules. Step count patterns during weekdays showed several significant peaks and troughs ( p < 0.01) and clearly reflected the kindergartens' daily schedules, except for Germany. For example, low numbers of steps were observed during afternoon naptimes and high numbers of steps during recess. In Germany, step count patterns did not show clear peaks and troughs, which can be explained by a less structured kindergarten schedule. On weekend days, differences in step count patterns were observed in the absolute number of steps in the afternoon trough and the period in which the evening peak occurred. Differences in step count patterns across the countries can be explained by differences in (school) policy, lifestyle habits, and culture. Therefore, it might be important to respond to these step count patterns and more specifically to tackle the inactive periods during interventions to promote physical activity in preschoolers.

Bioavailability of voriconazole in hospitalised patients.

PubMed

Veringa, Anette; Geling, Sanne; Span, Lambert F R; Vermeulen, Karin M; Zijlstra, Jan G; van der Werf, Tjip S; Kosterink, Jos G W; Alffenaar, Jan-Willem C

2017-02-01

An important element in antimicrobial stewardship programmes is early switch from intravenous (i.v.) to oral antimicrobial treatment, especially for highly bioavailable drugs. The antifungal agent voriconazole is available both in i.v. and oral formulations and bioavailability is estimated to be >90% in healthy volunteers, making this drug a suitable candidate for such a transition. Recently, two studies have shown that the bioavailability of voriconazole is substantially lower in patients. However, for both studies various factors that could influence the voriconazole serum concentration, such as inflammation, concomitant intake of food with oral voriconazole, and gastrointestinal complications, were not included in the evaluation. Therefore, in this study a retrospective chart review was performed in adult patients treated with both oral and i.v. voriconazole at the same dose and within a limited (≤5 days) time interval in order to evaluate the effect of switching the route of administration on voriconazole serum concentrations. A total of 13 patients were included. The mean voriconazole trough concentration was 2.28 mg/L [95% confidence interval (CI) 1.29-3.26 mg/L] for i.v. voriconazole administration and 2.04 mg/L (95% CI 0.78-3.30 mg/L) for oral administration. No significant difference was found in the mean oral and i.v. trough concentrations of voriconazole (P = 0.390). The mean bioavailability was 83.0% (95% CI 59.0-107.0%). These findings suggest that factors other than bioavailability may cause the observed difference in voriconazole trough concentrations between oral and i.v. administration in the earlier studies and stress the need for an antimicrobial stewardship team to guide voriconazole dosing. Copyright © 2016 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.

Daily Patterns of Preschoolers’ Objectively Measured Step Counts in Six European Countries: Cross-Sectional Results from the ToyBox-Study

PubMed Central

Van Stappen, Vicky; Latomme, Julie; Moreno, Luis; Socha, Piotr; Iotova, Violeta; Koletzko, Berthold; Manios, Yannis; Androutsos, Odysseas

2018-01-01

This study is part of the ToyBox-study, which is conducted in six European countries (Belgium, Bulgaria, Germany, Greece, Poland and Spain), aiming to develop a cost-effective kindergarten-based, family-involved intervention to prevent overweight and obesity in four- to six-year-old preschool children. In the current study, we aimed to examine and compare preschoolers’ step count patterns, across the six European countries. A sample of 3578 preschoolers (mean age: 4.8 ± 0.4) was included. Multilevel analyses were performed to take clustering of measurements into account. Based on the average hourly steps, step count patterns for the six European countries were created for weekdays and weekend days. The step count patterns during weekdays were related to the daily kindergarten schedules. Step count patterns during weekdays showed several significant peaks and troughs (p < 0.01) and clearly reflected the kindergartens’ daily schedules, except for Germany. For example, low numbers of steps were observed during afternoon naptimes and high numbers of steps during recess. In Germany, step count patterns did not show clear peaks and troughs, which can be explained by a less structured kindergarten schedule. On weekend days, differences in step count patterns were observed in the absolute number of steps in the afternoon trough and the period in which the evening peak occurred. Differences in step count patterns across the countries can be explained by differences in (school) policy, lifestyle habits, and culture. Therefore, it might be important to respond to these step count patterns and more specifically to tackle the inactive periods during interventions to promote physical activity in preschoolers. PMID:29414916

Cambrian potential indicated in Kentucky Rome trough

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harris, D.C.; Drahovzal, J.A.

1996-02-19

This paper reviews recent gas discoveries in the Kentucky Rome trough and the implications for future developments. It reviews the geology and stratigraphy of this structure and identifies the potential zones of production and trapping mechanisms. It provides results from geologic logs and seismic data to provide cross sectional and structural interpretations. Finally it discusses the gas composition of natural gas recovered from the basin.

CSPonD demonstrative project: Start-up process of a 25 kW prototype

NASA Astrophysics Data System (ADS)

Gil, Antoni; Grange, Benjamin; Perez, Victor G.; Tetreault-Friend, Melanie; Codd, Daniel S.; Calvet, Nicolas; Slocum, Alexander S.

2017-06-01

The current concept of commercial concentrated solar power (CSP) plants, based on the concept of a solar field, receiver, storage and power block, experienced significant growth in the past decades. The power block is the most well know part of the plant, while solar field depends on the receiver technology. The dominant receiver technologies are parabolic troughs and central towers. Most thermal energy storage (TES) relies on two tanks of molten salts, one hot and one cold serviced by pumps and piping systems. In spite of the technical development level achieved by these systems, efficiency is limited, mainly caused by thermal losses in piping, parasitic losses due to electric tracing and pumping and receiver limitations. In order to mitigate the these issues, a new concept called Concentrated Solar Power on Demand (CSPonD), was developed, consisting of a direct absorption Solar Salt CSP receiver which simultaneously acts as TES tank. Currently, in the frame of the flagship collaborative project between the Masdar Institute (UAE) and the Massachusetts Institute of Technology (USA) a 25 kW demonstrative prototype is in its final building phase at the Masdar Institute Solar Platform. The present paper, explains the demonstration prototype based on the CSPonD concept, with emphasis on the planned start-up process for the facility.

Photovoltaic concentrator application experiment to be located at Sea World Park, Orlando, Florida. Phase I. System Design. Final report, June 1, 1978-February 28, 1979

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kirpich, A.S.

1979-12-01

The General Electric/Sea World Photovoltaic Concentrator Application Experiment will be located at Sea World's Marine Park near Orlando, Florida. The experiment will consist of nine azimuth-tracking turntable arrays, each containing twenty-four elevation-tracking parabolic trough PV concentrators of a type developed on this contract. The system will produce a peak power output of 330 kW and an annual net electrical energy of 355 MWh corresponding to an annual direct normal insolation of 1375.5 kWh/m/sup 2/. A line-commutated DC/AC inverter controlled to operate at the solar array maximum power point will deliver three-phase power through a bidirectional transformer to a 13-kilovolt linemore » serving the Sea World Park. In addition to generating electrical power, the system will produce 3.56 x 10/sup 5/ ton-hours of cooling for air conditioning a nearby shark exhibit by supplying collected thermal energy to a lithium-bromide absorption chiller. With credit included for the amount of electricity that would be required to produce this cooling by a vapor compression cycle, the overall system efficiency is estimated to be 11.7 percent.« less

Temporal variability of the Circumpolar Deep Water inflow onto the Ross Sea continental shelf

NASA Astrophysics Data System (ADS)

Castagno, Pasquale; Falco, Pierpaolo; Dinniman, Michael S.; Spezie, Giancarlo; Budillon, Giorgio

2017-02-01

The intrusion of Circumpolar Deep Water (CDW) is the primary source of heat, salt and nutrients onto Antarctica's continental shelves and plays a major role in the shelf physical and biological processes. Different studies have analyzed the processes responsible for the transport of CDW across the Ross Sea shelf break, but until now, there are no continuous observations that investigate the timing of the intrusions. Also, few works have focused on the effect of the tides that control these intrusions. In the Ross Sea, the CDW intrudes onto the shelf in several locations, but mostly along the troughs. We use hydrographic observations and a mooring placed on the outer shelf in the middle of the Drygalski Trough in order to characterize the spatial and temporal variability of CDW inflow onto the shelf. Our data span from 2004 to the beginning of 2014. In the Drygalski Trough, the CDW enters as a 150 m thick layer between 250 and 400 m, and moves upward towards the south. At the mooring location, about 50 km from the shelf break, two main CDW cores can be observed: one on the east side of the trough spreading along the west slope of Mawson Bank from about 200 m to the bottom and the other one in the central-west side from 200 m to about 350 m depth. A signature of this lighter and relatively warm water is detected by the instruments on the mooring at bottom of the Drygalski Trough. High frequency periodic CDW intrusion at the bottom of the trough is related to the diurnal and spring/neap tidal cycles. At lower frequency, a seasonal variability of the CDW intrusion is noticed. A strong inflow of CDW is observed every year at the end of December, while the CDW inflow is at its seasonal minimum during the beginning of the austral fall. In addition an interannual variability is also evident. A change of the CDW intrusion before and after 2010 is observed.

Palaeo-ice stream pathways in the easternmost Amundsen Sea Embayment, West Antarctica

NASA Astrophysics Data System (ADS)

Klages, Johann P.; Kuhn, Gerhard; Graham, Alastair G. C.; Smith, James A.; Hillenbrand, Claus-Dieter; Nitsche, Frank O.; Larter, Rob D.; Gohl, Karsten

2015-04-01

Multibeam swath bathymetry datasets collected over the past two decades have been compiled to identify palaeo-ice stream pathways in the easternmost Amundsen Sea Embayment. We mapped 3010 glacial landforms to reconstruct palaeo-ice flow in the ~250 km-long Abbot Glacial Trough that was occupied by a large palaeo-ice stream, fed by two tributaries (Cosgrove and Abbot) that reached the continental shelf edge during the last maximum ice-sheet advance. The mapping has enabled a clear differentiation between glacial landforms interpreted as indicative of wet- (e.g. mega-scale glacial lineations) and cold-based ice (e.g. hill-hole pairs) during the last glaciation of the continental shelf. Both the regions of fast palaeo-ice flow within the palaeo-ice stream troughs, and the regions of slow palaeo-ice flow on adjacent seafloor highs (referred to as inter-ice stream ridges) additionally record glacial landforms such as grounding-zone wedges and recessional moraines that indicate grounding line stillstands of the ice sheet during the last deglaciation from the shelf. As the palaeo-ice stream flowed along a trough with variable geometry and variable subglacial substrate, it appears that trough sections characterized by constrictions and outcropping hard substrate that changes the bed gradient, led the pace of grounding-line retreat to slow and subsequently pause, resulting in the deposition of grounding-zone wedges. The stepped retreat recorded within the Abbot Glacial Trough corresponds well to post-glacial stepped retreat interpreted for the neighbouring Pine Island-Thwaites Palaeo-Ice Stream trough, thus suggesting a uniform pattern of episodic retreat across the eastern Amundsen Sea Embayment. The correlation of episodic retreat features with geological boundaries further emphasises the significance of subglacial geology in steering ice stream flow. Our new geomorphological map of the easternmost Amundsen Sea Embayment resolves the pathways of palaeo-ice streams that were probably all active during the last maximum extent of the ice sheet on this part of the shelf, and reveals the style of postglacial grounding-line retreat. Both are important input variables in ice sheet models and therefore can be used for validating the reliability of these models.

Space plasma physics research

NASA Technical Reports Server (NTRS)

Comfort, Richard H.; Horwitz, James L.

1993-01-01

During the course of this grant, work was performed on a variety of topics and there were a number of significant accomplishments. A summary of these accomplishments is included. The topics studied include empirical model data base, data reduction for archiving, semikinetic modeling of low energy plasma in the inner terrestrial magnetosphere and ionosphere, O(+) outflows, equatorial plasma trough, and plasma wave ray-tracing studies. A list of publications and presentations which have resulted from this research is also included.

Climatology of atmospheric circulation patterns of Arabian dust in western Iran.

PubMed

Najafi, Mohammad Saeed; Sarraf, B S; Zarrin, A; Rasouli, A A

2017-08-28

Being in vicinity of vast deserts, the west and southwest of Iran are characterized by high levels of dust events, which have adverse consequences on human health, ecosystems, and environment. Using ground based dataset of dust events in western Iran and NCEP/NCAR reanalysis data, the atmospheric circulation patterns of dust events in the Arabian region and west of Iran are identified. The atmospheric circulation patterns which lead to dust events in the Arabian region and western Iran were classified into two main categories: the Shamal dust events that occurs in warm period of year and the frontal dust events as cold period pattern. In frontal dust events, the western trough or blocking pattern at mid-level leads to frontogenesis, instability, and air uplift at lower levels of troposphere in the southwest of Asia. Non-frontal is other pattern of dust event in the cold period and dust generation are due to the regional circulation systems at the lower level of troposphere. In Shamal wind pattern, the Saudi Arabian anticyclone, Turkmenistan anticyclone, and Zagros thermal low play the key roles in formation of this pattern. Summer and transitional patterns are two sub-categories of summer Shamal wind pattern. In summer trough pattern, the mid-tropospheric trough leads to intensify the surface thermal systems in the Middle East and causes instability and rising of wind speed in the region. In synthetic pattern of Shamal wind and summer trough, dust is created by the impact of a trough in mid-levels of troposphere as well as existing the mentioned regional systems which are contributed in formation of summer Shamal wind pattern.

Morphology and sedimentology of glacigenic submarine fans on the west Greenland continental margin

NASA Astrophysics Data System (ADS)

O'Cofaigh, Colm; Hogan, Kelly A.; Dowdeswell, Julian A.; Jennings, Anne E.; Noormets, Riko; Evans, Jeffrey

2014-05-01

Along the West Greenland continental margin adjoining Baffin Bay, bathymetric data show a series of large submarine fans located at the mouths of cross-shelf troughs. Two of these fans, the Uummannaq Fan and the Disko Fan are trough-mouth fans built largely of debris delivered from ice sheet outlets of the Greenland Ice Sheet during past glacial maxima. On the Uummannaq Fan glacigenic debris flow deposits occur on the upper slope and extend to at least 1800 m water depth in front of the trough-mouth. The debris flow deposits are related to the remobilisation of subglacial debris that was delivered onto the upper slope at times when an ice stream was positioned at the shelf edge. In contrast, sedimentary facies from the northern sector of the fan are characterised by hemipelagic and ice-rafted sediments and turbidites; glacigenic debris flows are notably absent in cores from this region. Further south along the Greenland continental margin the surface of the Disko Fan is prominently channelised and associated sediments are acoustically stratified. Although glacigenic debris flow deposits do occur on the upper Disko Fan, sediments recovered in cores from elsewhere on the fan record the influence of turbidity current and meltwater sedimentation. The channelised form of the Disko fan contrasts markedly with that of the Uummannaq Fan and, more widely, with trough mouth fans from the Polar North Atlantic. Collectively these data highlight the variability of glacimarine depositional processes operating on trough-mouth fans on high-latitude continental slopes and show that glacigenic debris flows are but one of a number of mechanisms by which such large glacially-influenced depocentres form.

Earth Observations

NASA Image and Video Library

2013-06-21

ISS036-E-011034 (21 June 2013) --- The Salton Trough is featured in this image photographed by an Expedition 36 crew member on the International Space Station. The Imperial and Coachella Valleys of southern California – and the corresponding Mexicali Valley and Colorado River Delta in Mexico – are part of the Salton Trough, a large geologic structure known to geologists as a graben or rift valley that extends into the Gulf of California. The trough is a geologically complex zone formed by interaction of the San Andreas transform fault system that is, broadly speaking, moving southern California towards Alaska; and the northward motion of the Gulf of California segment of the East Pacific Rise that continues to widen the Gulf of California by sea-floor spreading. According to scientists, sediments deposited by the Colorado River have been filling the northern rift valley (the Salton Trough) for the past several million years, excluding the waters of the Gulf of California and providing a fertile environment – together with irrigation—for the development of extensive agriculture in the region (visible as green and yellow-brown fields at center). The Salton Sea, a favorite landmark of astronauts in low Earth orbit, was formed by an irrigation canal rupture in 1905, and today is sustained by agricultural runoff water. A wide array of varying landforms and land uses in the Salton Trough are visible from space. In addition to the agricultural fields and Salton Sea, easily visible metropolitan areas include Yuma, AZ (lower left); Mexicali, Baja California, Mexico (center); and the San Diego-Tijuana conurbation on the Pacific Coast (right). The approximately 72-kilometer-long Algodones Dunefield is visible at lower left.

How older people in the United States and Germany fared in the growth years of the 1980s: a cross-sectional versus a longitudinal view.

PubMed

Burkhauser, R V; Cutts, A C; Lillard, D R

1999-09-01

The goal of the study was to show that cross-sectional and longitudinal data yield dramatically different answers to a basic question: "How did older persons fare in the recovery years of the 1980s?" The United States Panel Study of Income Dynamics and the German Socio-Economic Panel are used cross-sectionally to capture changes in the economic well-being of older persons in the trough and peak years of the 1980s business cycle, and longitudinally to trace how the economic well-being of a given cohort of older persons changed over those years. Kernel density estimation is then used to show how the distribution of economic well-being of these populations changed over these years. Cross-sectional comparisons confirm that persons aged 65 and over in the peak year were better off than persons aged 65 and over in the trough year in both countries. Longitudinal comparisons, however, show that persons aged 65 and over in the trough year who survived to the peak year received a substantially smaller share of the rewards of economic recovery than cross-sectional comparisons imply. Moreover, the entire income distribution of older persons in the United States shifted downwards. Compositional changes in the cross-sectional data, caused by the entry of high-income persons who are young in the peak year but old in the trough year, obscure the decline in the economic well-being of the cohort of older persons who survived the trough year, in cross-sectional comparisons of older populations in the United States in the 1980s.

On Local Ionization Equilibrium and Disk Winds in QSOs

NASA Astrophysics Data System (ADS)

Pereyra, Nicolas A.

2014-11-01

We present theoretical C IV λλ1548,1550 absorption line profiles for QSOs calculated assuming the accretion disk wind (ADW) scenario. The results suggest that the multiple absorption troughs seen in many QSOs may be due to the discontinuities in the ion balance of the wind (caused by X-rays), rather than discontinuities in the density/velocity structure. The profiles are calculated from a 2.5-dimensional time-dependent hydrodynamic simulation of a line-driven disk wind for a typical QSO black hole mass, a typical QSO luminosity, and for a standard Shakura-Sunyaev disk. We include the effects of ionizing X-rays originating from within the inner disk radius by assuming that the wind is shielded from the X-rays from a certain viewing angle up to 90° ("edge on"). In the shielded region, we assume constant ionization equilibrium, and thus constant line-force parameters. In the non-shielded region, we assume that both the line-force and the C IV populations are nonexistent. The model can account for P-Cygni absorption troughs (produced at edge on viewing angles), multiple absorption troughs (produced at viewing angles close to the angle that separates the shielded region and the non-shielded region), and for detached absorption troughs (produced at an angle in between the first two absorption line types); that is, the model can account for the general types of broad absorption lines seen in QSOs as a viewing angle effect. The steady nature of ADWs, in turn, may account for the steady nature of the absorption structure observed in multiple-trough broad absorption line QSOs. The model parameters are M bh = 109 M ⊙ and L disk = 1047 erg s-1.

Nationwide conversion to generic tacrolimus in pediatric kidney transplant recipients.

PubMed

Naicker, Derisha; Reed, Peter W; Ronaldson, Jane; Kara, Tonya; Wong, William; Prestidge, Chanel

2017-11-01

Bioequivalence between Tacrolimus Prograf® and generic tacrolimus formulations has been demonstrated in adult populations, however clinical experience and safety data regarding generic tacrolimus in pediatric transplant recipients is limited. This study aimed to evaluate conversion from Tacrolimus Prograf® to Sandoz® in pediatric renal transplant recipients nationwide. The primary outcome was a change in mean trough tacrolimus concentration. Additionally, changes in tacrolimus intra-patient coefficient of variation (CoV), allograft function, requirement for dose adjustments, and episodes of biopsy-proven rejection were evaluated. Retrospective cohort study in 37 pediatric renal transplant recipients who switched to Tacrolimus Sandoz®. Each patient had three pre-conversion tacrolimus trough and creatinine concentrations within the 4 months prior and three post-conversion concentrations on day 3, 10, and the next subsequent level. Mean pre- and post-conversion tacrolimus trough concentrations and glomerular filtration rate (eGFR) were calculated. Tacrolimus concentration, CoV, and creatinine differences were compared by paired t test. Thirty-seven patients (41% females, age 3-18 years) were included. Average intra-patient difference in trough tacrolimus concentration was 0.05μg/l (95% CI -0.37 to 0.47). Average intra-patient difference in eGFR was -1.20 ml/min/1.73 2 (95% CI -3.53 to 1.13). Three patients had acute rejection during 12 months post-conversion compared to none during 12 months pre-conversion. Pediatric renal transplant recipients can be converted from Tacrolimus Prograf® to Sandoz® with negligible change in trough concentration, dose adjustments, or immediate allograft function. Of concern was the number of acute rejection episodes, however non-adherence contributed to at least one episode and this difference was determined clinically and statistically not significant.

Constraints on mantle melt geometries from body wave attenuation in the Salton Trough and Snake River Plain

NASA Astrophysics Data System (ADS)

Byrnes, J. S.; Bezada, M.

2017-12-01

Melt can be retained in the mantle at triple junctions between grain boundaries, be spread in thin films along two-grain boundaries, or be organized by shear into elongate melt-rich bands. Which of these geometries is most prevalent is unknown. This ambiguity makes the interpretation of anomalous seismic velocities and quality factors difficult, since different geometries would result in different mechanical effects. Here, we compare observations of seismic attenuation beneath the Salton Trough and the Snake River Plain; two regions where the presence of melt has been inferred. The results suggest that seismic attenuation is diagnostic of melt geometry. We measure the relative attenuation of P waves from deep focus earthquakes using a time-domain method. Even though the two regions are underlain by comparably strong low-velocity anomalies, their attenuation signature is very different. The upper mantle beneath the Salton Trough is sufficiently attenuating that the presence of melt must lower Qp, while attenuation beneath the Snake River Plain is not anomalous with respect to surrounding regions. These seemingly contradictory results can be reconciled if different melt geometries characterize each region. SKS splitting from the Salton Trough suggests that melt is organized into melt-rich bands, while this is not the case for the Snake River Plain. We infer that beneath the Snake River Plain melt is retained at triple junctions between grain boundaries, a geometry that is not predicted to cause seismic attenuation. More elongate geometries beneath the Salton Trough may cause seismic attenuation via the melt-squirt mechanism. In light of these results, we conclude that prior observations of low seismic velocities with somewhat high quality factors beneath the East Pacific Rise and Southern California suggest that melt does not organize into elongate bands across much of the asthenosphere.

The nature of the crust under Cayman Trough from gravity

USGS Publications Warehouse

ten Brink, Uri S.; Coleman, D.F.; Dillon, William P.

2002-01-01

Considerable crustal thickness variations are inferred along Cayman Trough, a slow-spreading ocean basin in the Caribbean Sea, from modeling of the gravity field. The crust to a distance of 50 km from the spreading center is only 2–3 km thick in agreement with dredge and dive results. Crustal thickness increases to ∼5.5 km at distances between 100 and 430 km west of the spreading center and to 3.5–6 km at distances between 60 and 370 km east of the spreading center. The increase in thickness is interpreted to represent serpentinization of the uppermost mantle lithosphere, rather than a true increase in the volume of accreted ocean crust. Serpentinized peridotite rocks have indeed been dredged from the base of escarpments of oceanic crust rocks in Cayman Trough. Laboratory-measured density and P-wave speed of peridotite with 40–50% serpentine are similar to the observed speed in published refraction results and to the inferred density from the model. Crustal thickness gradually increases to 7–8 km at the far ends of the trough partially in areas where sea floor magnetic anomalies were identified. Basement depth becomes gradually shallower starting 250 km west of the rise and 340 km east of the rise, in contrast to the predicted trend of increasing depth to basement from cooling models of the oceanic lithosphere. The gradual increase in apparent crustal thickness and the shallowing trend of basement depth are interpreted to indicate that the deep distal parts of Cayman Trough are underlain by highly attenuated crust, not by a continuously accreted oceanic crust.

Effect of azilsartan versus candesartan on morning blood pressure surges in Japanese patients with essential hypertension

PubMed Central

Kario, Kazuomi; Enya, Kazuaki; Sugiura, Kenkichi; Ikeda, Yoshinori

2014-01-01

Morning blood pressure (BP) surge is reported as a risk factor for cardiovascular events and end-organ damage independent of the 24-h BP level. Controlling morning BP surge is therefore important to help prevent onset of cardiovascular disease. We compared the efficacy of azilsartan and candesartan in controlling morning systolic BP (SBP) surges by analyzing relevant ambulatory BP monitoring data in patients with/without baseline BP surges. As part of a 16-week randomized, double-blind study of azilsartan (20–40 mg once daily) and candesartan (8–12 mg once daily) in Japanese patients with essential hypertension, an exploratory analysis was carried out using ambulatory BP monitoring at baseline and week 14. The effects of study drugs on morning BP surges, including sleep trough surge (early morning SBP minus the lowest night-time SBP) and prewaking surge (early morning SBP minus SBP before awakening), were evaluated. Patients with sleep trough surge of at least 35 mmHg were defined by the presence of a morning BP surge (the ‘surge group’). Sleep trough surge and prewaking surge data were available at both baseline and week 14 in 548 patients, 147 of whom (azilsartan 76; candesartan 71) had a baseline morning BP surge. In surge group patients, azilsartan significantly reduced both the sleep trough surge and the prewaking surge at week 14 compared with candesartan (least squares means of the between-group differences −5.8 mmHg, P=0.0395; and −5.7 mmHg, P=0.0228, respectively). Once-daily azilsartan improved sleep trough surge and prewaking surge to a greater extent than candesartan in Japanese patients with grade I–II essential hypertension. PMID:24710336

Effect of azilsartan versus candesartan on morning blood pressure surges in Japanese patients with essential hypertension.

PubMed

Rakugi, Hiromi; Kario, Kazuomi; Enya, Kazuaki; Sugiura, Kenkichi; Ikeda, Yoshinori

2014-06-01

Morning blood pressure (BP) surge is reported as a risk factor for cardiovascular events and end-organ damage independent of the 24-h BP level. Controlling morning BP surge is therefore important to help prevent onset of cardiovascular disease. We compared the efficacy of azilsartan and candesartan in controlling morning systolic BP (SBP) surges by analyzing relevant ambulatory BP monitoring data in patients with/without baseline BP surges. As part of a 16-week randomized, double-blind study of azilsartan (20-40 mg once daily) and candesartan (8-12 mg once daily) in Japanese patients with essential hypertension, an exploratory analysis was carried out using ambulatory BP monitoring at baseline and week 14. The effects of study drugs on morning BP surges, including sleep trough surge (early morning SBP minus the lowest night-time SBP) and prewaking surge (early morning SBP minus SBP before awakening), were evaluated. Patients with sleep trough surge of at least 35 mmHg were defined by the presence of a morning BP surge (the 'surge group'). Sleep trough surge and prewaking surge data were available at both baseline and week 14 in 548 patients, 147 of whom (azilsartan 76; candesartan 71) had a baseline morning BP surge. In surge group patients, azilsartan significantly reduced both the sleep trough surge and the prewaking surge at week 14 compared with candesartan (least squares means of the between-group differences -5.8 mmHg, P=0.0395; and -5.7 mmHg, P=0.0228, respectively). Once-daily azilsartan improved sleep trough surge and prewaking surge to a greater extent than candesartan in Japanese patients with grade I-II essential hypertension.

Hydrogen production by the solar-powered hybrid sulfur process: Analysis of the integration of the CSP and chemical plants in selected scenarios

NASA Astrophysics Data System (ADS)

Liberatore, Raffaele; Lanchi, Michela; Turchetti, Luca

2016-05-01

The Hybrid Sulfur (HyS) is a water splitting process for hydrogen production powered with high temperature nuclear heat and electric power; among the numerous thermo-chemical and thermo-electro-chemical cycles proposed in the literature, such cycle is considered to have a particularly high potential also if powered by renewable energy. SOL2HY2 (Solar to Hydrogen Hybrid Cycles) is a 3 year research project, co-funded by the Fuel Cells and Hydrogen Joint Undertaking (FCH JU). A significant part of the project activities are devoted to the analysis and optimization of the integration of the solar power plant with the chemical, hydrogen production plant. This work reports a part of the results obtained in such research activity. The analysis presented in this work builds on previous process simulations used to determine the energy requirements of the hydrogen production plant in terms of electric power, medium (<550°C) and high (>550°C) temperature heat. For the supply of medium temperature (MT) heat, a parabolic trough CSP plant using molten salts as heat transfer and storage medium is considered. A central receiver CSP (Concentrated Solar Power) plant is considered to provide high temperature (HT) heat, which is only needed for sulfuric acid decomposition. Finally, electric power is provided by a power block included in the MT solar plant and/or drawn from the grid, depending on the scenario considered. In particular, the analysis presented here focuses on the medium temperature CSP plant, possibly combined with a power block. Different scenarios were analysed by considering plants with different combinations of geographical location and sizing criteria.

Sirolimus Pharmacokinetics in Early Postmyeloablative Pediatric Blood and Marrow Transplantation

PubMed Central

Goyal, Rakesh K.; Han, Kelong; Wall, Donna A.; Pulsipher, Michael A.; Bunin, Nancy; Grupp, Stephan A.; Mada, Sripal R.; Venkataramanan, Raman

2014-01-01

This study examined the pharmacokinetics of sirolimus in pediatric allogeneic blood and marrow transplantation (BMT) recipients in the presence and absence of concomitant fluconazole. Forty pediatric BMT recipients received a daily oral dose of sirolimus and a continuous i.v. infusion of tacrolimus for graft-versus-host disease prophylaxis. Fluconazole was administered i.v. to 19 patients and orally to 6 patients. Full pharmacokinetic profiles of sirolimus within a single dosing interval were collected. Whole-blood sirolimus concentrations were measured by HPLC/mass spectrometry. Noncompartmental analysis was performed using WinNonlin. Nonlinear mixed-effects pharmacokinetic models were developed using NONMEM following standard procedures. The mean ± SD sirolimus trough level before the dose (C0) was 8.0 ± 4.6 ng/mL (range, 1.8–21.6 ng/mL). The peak concentration was 19.9 ± 11.8 ng/mL (range, 3.9–46.1 ng/mL), and the trough level 24 hours later (C24) was 9.1 ± 5.3 ng/mL (range, 1.0–19.1 ng/mL). The terminal disposition half-life (T1/2) was 24.5 ± 11.2 hours (range, 5.8–53.2 hours), and the area under the concentration-versus-time curve (AUC0–24) was 401.1 ± 316.3 ng·h/mL (range, 20.7–1332.3 ng·h/mL). In patients at steady state, C0 and C24 were closely correlated (R2 = 0.77) with a slope of 0.99, indicating the achievement of steady state. C24 was 1.7-fold greater (P = .036) and AUC0–24 was 2-fold greater (P = .012) in Caucasian patients (n = 22) compared with Hispanic patients (n = 9). The average apparent oral clearance was 3-fold greater (P = .001) and the apparent oral volume of distribution was 2-fold greater (P = .018) in patients age ≤12 years compared with those age >12 years. C24 was significantly lower in patients (n = 10) who developed grade III–IV aGVHD (n = 10) than in those with grade 0-II aGVHD (n = 22) (6.1 ± 2.9 ng/mL versus 9.4 ± 5.5 ng/mL; P = .044). Dose-normalized sirolimus trough concentrations were significantly higher in patients receiving concomitant fluconazole therapy compared with those not receiving fluconazole (C0: 3.9 ± 2.5 versus 2.4 ± 1.5 ng/mL/mg, P = .030; C24: 4.8 ± 3.3 versus 2.5 ± 1.7 ng/mL/mg, P = .018). This pharmacokinetic study of sirolimus in pediatric patients documents a large interindividual variability in the exposure of sirolimus. Steady-state trough blood concentrations were correlated with drug exposure. Trough concentrations were higher with a concomitant use of fluconazole and were higher in Caucasian patients than in Hispanic patients. Oral clearance was greater in children age ≤12 years than in older children and adolescents. With therapeutic drug monitoring, the majority (79%) of sirolimus trough levels could be maintained within the target range (3–12 ng/mL). This study provides a rationale and support for dose adjustments of sirolimus based on steady-state blood concentrations aimed at achieving a target concentration to minimize toxicity and maximize therapeutic benefits in pediatric BMT recipients. PMID:23266742

Post-early cretaceous landform evolution along the western margin of the banca~nnia trough, western nsw

USGS Publications Warehouse

Gibson, D.L.

2000-01-01

Previously undated post-Devonian sediments outcropping north of Fowlers Gap station near the western margin of the Bancannia Trough are shown by plant macro- and microfossil determinations to be of Early Cretaceous (most likely Neocomian and/or Aptian) age, and thus part of the Eromanga Basin. They are assigned to the previously defined Telephone Creek Formation. Study of the structural configuration of this unit and the unconformably underlying Devonian rocks suggests that the gross landscape architecture of the area results from post-Early Cretaceous monoclinal folding along blind faults at the western margin of the trough, combined with the effects of differential erosion. This study shows that, while landscape evolution in the area has been dynamic, the major changes that have occurred are on a geological rather than human timescale.

Element of an inductive coupler

DOEpatents

Hall, David R.; Fox, Joe

2006-08-15

An element for an inductive coupler in a downhole component comprises magnetically conductive material, which is disposed in a recess in annular housing. The magnetically conductive material forms a generally circular trough. The circular trough comprises an outer generally U-shaped surface, an inner generally U-shaped surface, and two generally planar surfaces joining the inner and outer surfaces. The element further comprises pressure relief grooves in at least one of the surfaces of the circular trough. The pressure relief grooves may be scored lines. Preferably the pressure relief grooves are parallel to the magnetic field generated by the magnetically conductive material. The magnetically conductive material is selected from the group consisting of soft iron, ferrite, a nickel iron alloy, a silicon iron alloy, a cobalt iron alloy, and a mu-metal. Preferably, the annular housing is a metal ring.

Initial Investigation into the Potential of CSP Industrial Process Heat for the Southwest United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kurup, Parthiv; Turchi, Craig

2015-11-01

After significant interest in the 1970s, but relatively few deployments, the use of solar technologies for thermal applications, including enhanced oil recovery (EOR), desalination, and industrial process heat (IPH), is again receiving global interest. In particular, the European Union (EU) has been a leader in the use, development, deployment, and tracking of Solar Industrial Process Heat (SIPH) plants. The objective of this study is to ascertain U.S. market potential of IPH for concentrating collector technologies that have been developed and promoted through the U.S. Department of Energy's Concentrating Solar Power (CSP) Program. For this study, the solar-thermal collector technologies ofmore » interest are parabolic trough collectors (PTCs) and linear Fresnel (LF) systems.« less

Dynamic modelling and simulation of linear Fresnel solar field model based on molten salt heat transfer fluid

NASA Astrophysics Data System (ADS)

Hakkarainen, Elina; Tähtinen, Matti

2016-05-01

Demonstrations of direct steam generation (DSG) in linear Fresnel collectors (LFC) have given promising results related to higher steam parameters compared to the current state-of-the-art parabolic trough collector (PTC) technology using oil as heat transfer fluid (HTF). However, DSG technology lacks feasible solution for long-term thermal energy storage (TES) system. This option is important for CSP technology in order to offer dispatchable power. Recently, molten salts have been proposed to be used as HTF and directly as storage medium in both line-focusing solar fields, offering storage capacity of several hours. This direct molten salt (DMS) storage concept has already gained operational experience in solar tower power plant, and it is under demonstration phase both in the case of LFC and PTC systems. Dynamic simulation programs offer a valuable effort for design and optimization of solar power plants. In this work, APROS dynamic simulation program is used to model a DMS linear Fresnel solar field with two-tank TES system, and example simulation results are presented in order to verify the functionality of the model and capability of APROS for CSP modelling and simulation.

Solar thermal organic rankine cycle for micro-generation

NASA Astrophysics Data System (ADS)

Alkahli, N. A.; Abdullah, H.; Darus, A. N.; Jalaludin, A. F.

2012-06-01

The conceptual design of an Organic Rankine Cycle (ORC) driven by solar thermal energy is developed for the decentralized production of electricity of up to 50 kW. Conventional Rankine Cycle uses water as the working fluid whereas ORC uses organic compound as the working fluid and it is particularly suitable for low temperature applications. The ORC and the solar collector will be sized according to the solar flux distribution in the Republic of Yemen for the required power output of 50 kW. This will be a micro power generation system that consists of two cycles, the solar thermal cycle that harness solar energy and the power cycle, which is the ORC that generates electricity. As for the solar thermal cycle, heat transfer fluid (HTF) circulates the cycle while absorbing thermal energy from the sun through a parabolic trough collector and then storing it in a thermal storage to increase system efficiency and maintains system operation during low radiation. The heat is then transferred to the organic fluid in the ORC via a heat exchanger. The organic fluids to be used and analyzed in the ORC are hydrocarbons R600a and R290.

TOPDAQ Acquisition Utility Beta version 1.0

DOE Office of Scientific and Technical Information (OSTI.GOV)

MOreno, Mario; & Barret, Keith

2010-01-07

This TOPDAQ Acquisition Utility uses 5 digital cameras mounted on a vertical pole, maintained in a vertical position using sensors and actuators, to take photographs of an RP-2 or RP-3 module, one camera for each row (4) and one in the center for driving, when the module is at 0 degrees, or facing the eastern horizon. These photographs and other data collected at the same time the pictures are taken are analyzed by the TOPAAP Analysis Utility. The TOPCAT implemented by the TOPDAQ Acquisition Utility and TOPAAP Analysis Utility programs optimizes the alignment of each RP in a module onmore » a parabolic trough solar collector array (SCA) to maximize the amount of solar energy intercepted by the solar receiver. The camera fixture and related hardware are mounted on a pickup truck and driven between rows in a parabolic trough solar power plant. An ultrasonic distance meter is used to maintain the correct distance between the cameras and the RP module. Along with the two leveling actuators, a third actuator is used to maintain a proper relative vertical position between the cameras and the RP module. The TOPDAQ Acquisition Utility facilitates file management by keeping track of which RP module data is being taken and also controls the exposure levels for each camera to maintain a high contract ratio in the photograph even as the available daylight changes throughout the day. The theoretical TOPCAT hardware and software support the current industry standard RP-2 and RP-3 module geometries.« less

Quasar Outflows and AGN Feedback in the Extreme UV: HST/COS Observations of QSO HE0238-1904

NASA Astrophysics Data System (ADS)

Arav, Nahum; Borguet, B.; Chamberlain, C.; Edmonds, D.; Danforth, C.

2014-01-01

Spectroscopic observations of quasar outflows at rest-frame 500-1000 Angstrom have immense diagnostic power. We present analyses of such data, where absorption troughs from three important ions are measured: first, O IV and O IV* that allow us to obtain the distance of high ionization outflows from the AGN; second, Ne VIII and Mg X that are sensitive to the very high ionization phase of the outflow. Their inferred column densities, combined with those of troughs from O VI, N IV, and H I, yield two important results: 1) The outflow shows two ionization phases, where the high ionization phase carries the bulk of the material. This is similar to the situation seen in x-ray warm absorber studies. Furthermore, the low ionization phase is inferred to have a volume filling factor of 10^(-5)-10^(-6). 2) From the O IV to O IV* column density ratio, and the knowledge of the ionization parameter, we determine a distance of 3000 pc. from the outflow to the central source. Since this is a typical high ionization outflow, we can determine robust values for the mass flux and kinetic luminosity of the outflow: 40 solar masses per year and 10^45 ergs/s, respectively, where the latter is roughly equal to 1% of the bolometric luminosity. Such a large kinetic luminosity and mass flow rate measured in a typical high ionization wind suggests that quasar outflows are a major contributor to AGN feedback mechanisms.

To v∞ and beyond! The He I absorption variability across the 2014.6 periastron passage of η Carinae

NASA Astrophysics Data System (ADS)

Richardson, Noel D.; Madura, Thomas I.; St-Jean, Lucas; Moffat, Anthony F. J.; Gull, Theodore R.; Russell, Christopher M. P.; Damineli, Augusto; Teodoro, Mairan; Corcoran, Michael F.; Walter, Frederick M.; Clementel, Nicola; Groh, José H.; Hamaguchi, Kenji; Hillier, D. John

2016-09-01

We have monitored the massive binary star η Carinae with the CTIO/Small and Moderate Aperture Research Telescope System 1.5 m telescope and CHIRON spectrograph from the previous apastron passage of the system through the recent 2014.6 periastron passage. Our monitoring has resulted in a large, homogeneous data set with an unprecedented time-sampling, spectral resolving power, and signal to noise. This allowed us to investigate temporal variability previously unexplored in the system and discover a kinematic structure in the P Cygni absorption troughs of neutral helium wind lines. The features observed occurred prior to the periastron passage and are seen as we look through the trailing arm of the wind-wind collision shock cone. We show that the bulk of the variability is repeatable across the last five periastron passages, and that the absorption occurs in the inner 230 au of the system. In addition, we found an additional, high-velocity absorption component superimposed on the P Cygni absorption troughs that has been previously unobserved in these lines, but which bears resemblance to the observations of the He I λ10830 Å feature across previous cycles. Through a comparison of the current smoothed particle hydrodynamical simulations, we show that the observed variations are likely caused by instabilities in the wind-wind collision region in our line of sight, coupled with stochastic variability related to clumping in the winds.

Modulations of Driven Nonlinear Surface Waves on Water and Liquid Helium-4.

DTIC Science & Technology

1985-06-01

loop to control drive amplitude. 63 CHAPTER III. DATA AND INTERPRETATION. Section 5. Cockscombs. 25. Cockscomb in water at f/30. 67 26. Double...annular trough, sealed and then partially filled with normal or superfluid helium, is oscillated vertically and supported 6 . . ... . . . . . 41 700...44 0 .0 0 00 loudspeaker surface wave sealed trough transducer shel oo •Figure 3. Schmatic of the helium experiment. 8 r

Current status of the western gray squirrel population in the Puget Trough, Washington.

Treesearch

R. Bayrakci; A.B. Carey; T.M. Wilson

2001-01-01

The Puget Trough population of Washington’s state-threatened western gray squirrel is centered in Oregon white oak ecotones adjacent to conifer forests and prairies on the Fort Lewis Military Reservation. Our goal was to determine the current status of western gray squirrels in this region. In 1998, we found five western gray squirrels in 538 hours of foot surveys in...

Heavy precipitation episodes in the Western Mediterranean : Use of a semi-Lagrangian advection model for the fine-scale description of upper-level troughs

NASA Astrophysics Data System (ADS)

Gauthier, N.; Claud, C.; Funatsu, B. M.; Chaboureau, J.-P.; Argence, S.; Lambert, D.; Richard, E.; Hauchecorne, A.; Arbogast, P.; Maynard, K.

2009-09-01

Heavy precipitation events over the Mediterranean Sea are generally associated with upper-level troughs. The mesoscale structures of such troughs are however not well reproduced by the atmospheric analyses due to inappropriate spatial resolution. We propose here to use a semi-Lagrangian advection model called MIMOSA (Modélisation Isentrope du transport Méso-échelle de l'Ozone Stratosphérique par Advection) initially developed to describe stratospheric filaments, to calculate fine-scale Potential Vorticity (PV) fields on isentropic surfaces near the tropopause. After a description of MIMOSA, we will focus on the model-generated PV fields for several high impact weather cases that occurred over the Western Mediterreanean Sea. We will demonstrate the ability of MIMOSA to resolve fine scale structures of upper-level troughs considering the Algiers' flash flood, which occurred on November 2001, and then a heavy precipitation event over southeast France on the 5-6 September 2005. Finally, with a PV inversion method, we will show the impact of the fine scales PV structures as depicted by MIMOSA to improve the numerical simulation of a « hurricane » that hit Italy in September 2006, both in terms of surface pressure and precipitation forecasts.

Microbial Community in the Hydrothermal System at Southern Mariana Trough

NASA Astrophysics Data System (ADS)

Kato, S.; Itahashi, S.; Kakegawa, T.; Utsumi, M.; Maruyama, A.; Ishibashi, J.; Marumo, K.; Urabe, T.; Yamagishi, A.

2004-12-01

There is unique ecosystem around deep-sea hydrothermal area. Living organisms are supported by chemical free energy provided by the hydrothermal water. The ecosystem is expected to be similar to those in early stage of life history on the earth, when photosynthetic organisms have not emerged. In this study, we have analyzed the microbial diversity in the hydrothermal area at southern Mariana trough. In the "Archaean Park Project" supported by special Coordination Fund, four holes were bored and cased by titanium pipes near hydrothermal vents in the southern Mariana trough in 2004. Hydrothermal fluids were collected from these cased holes and natural vents in this area. Microbial cells were collected by filtering the hydrothermal fluid in situ or in the mother sip. Filters were stored at -80C and used for DNA extraction. Chimneys at this area was also collected and stored at -80C. The filters and chimney samples were crushed and DNA was extracted. DNA samples were used for amplification of 16S rDNA fragments by PCR using archaea specific primers and universal primers. The PCR fragments were cloned and sequenced. These PCR clones of different samples will be compared. We will extend our knowledge about microbiological diversity at Southern Mariana trough to compare the results obtained at other area.

Inductive coupler for downhole components and method for making same

DOEpatents

Hall, David R.; Hall, Jr., H. Tracy; Pixton, David S.; Dahlgren, Scott; Briscoe, Michael A.; Sneddon, Cameron; Fox, Joe

2006-05-09

The present invention includes a method of making an inductive coupler for downhole components. The method includes providing an annular housing, preferably made of steel, the housing having a recess. A conductor, preferably an insulated wire, is also provided along with a plurality of generally U-shaped magnetically conducting, electrically insulating (MCEI) segments. Preferably, the MCEI segments comprise ferrite. An assembly is formed by placing the plurality of MCEI segments within the recess in the annular housing. The segments are aligned to form a generally circular trough. A first portion of the conductor is placed within the circular trough. This assembly is consolidated with a meltable polymer which fills spaces between the segments, annular housing and the first portion of the conductor. The invention also includes an inductive coupler including an annular housing having a recess defined by a bottom portion and two opposing side wall portions. At least one side wall portion includes a lip extending toward but not reaching the other side wall portion. A plurality of generally U-shaped MCEI segments, preferably comprised of ferrite, are disposed in the recess and aligned so as to form a circular trough. The coupler further includes a conductor disposed within the circular trough and a polymer filling spaces between the segments, the annular housing and the conductor.

Difference of the seismic structure between the Hyuga-nada and the Nankai seismogenic segments

NASA Astrophysics Data System (ADS)

Yamamoto, Y.; Obana, K.; Takahashi, T.; Nakanishi, A.; Kodaira, S.; Kaneda, Y.

2010-12-01

In the Nankai Trough, three major seismogenic zones of megathrust earthquake exist (Tokai, Tonankai and Nankai earthquake regions). The Hyuga-nada region was distinguished from these seismogenic zones because of the lack of megathrust earthquake. In the Hyuga-nada region, interplate earthquakes of M~7 occur repeatedly at intervals of about 20 years whereas no megathrust (M > 8) earthquakes had been recognized up to now. However, recent studies show the possibility of simultaneous rupture of the Tokai, Tonankai, Nankai and Hyuga-nada segments was also pointed out [e.g., Hori et al., 2009 AOGS]. To understand the possibility of seismic linkage of Nankai and Hyuga-nada segments, Japan Agency for Marine-Earth Science and Technology has been carried out a wide-angle active source survey and local seismic observation in the western end of the Nankai seismogenic zone, as a part of Research concerning Interaction Between the Tokai, Tonankai and Nankai Earthquakes' funded by Ministry of Education, Culture, Sports, Science and Technology, Japan. Nakanishi et al [2009, AGU] showed that subducting Philippine Sea Plate can be divided into three zones and there is the zone of the thin oceanic crust of the subducting Philippine Sea Plate between Nankai segment and Kyushu-Palau Ridge segment by analyzing of the active source survey. Deep structure of the subducting slab is also important to consider the possibility of the seismic linkage and the location of the boundary among three zones described above. To obtain the deep seismic image, we performed a three-dimensional seismic tomography using the local seismic data recorded on 158 ocean bottom seismographs and 105 land seismic stations. From these data, we could detect 1141 earthquakes in the Hyuga-nada region. From the result of hypocenter relocation, microseismicity near the trough axis is active on the western part of the ‘thin oceanic crust’, whereas inactive on the eastern part. Besides, velocity structure of the uppermost part of the subducting slab mantle shows spatial heterogeneities. In the thin oceanic crust zone, high velocity slab mantle is imaged from near the trough to coastline. On the other hands, there is low velocity zone in the slab mantle near the trough axis in the Kyusyu-Palau Ridge segment. This low velocity zone may be related to the location of the eastern end of subducted Kyusyu-Palau Ridge.

Association Between Low Trough Levels of Vedolizumab During Induction Therapy for Inflammatory Bowel Diseases and Need for Additional Doses Within 6 Months.

PubMed

Williet, Nicolas; Boschetti, Gilles; Fovet, Marion; Di Bernado, Thomas; Claudez, Pierre; Del Tedesco, Emilie; Jarlot, Camille; Rinaldi, Leslie; Berger, Anne; Phelip, Jean-Marc; Flourie, Bernard; Nancey, Stéphane; Paul, Stéphane; Roblin, Xavier

2017-11-01

We investigated whether serum trough levels of vedolizumab, a humanized monoclonal antibody against integrin α4β7, during the induction phase of treatment can determine whether patients will need additional doses (optimization of therapy) within the first 6 months. We conducted an observational study of 47 consecutive patients with Crohn's disease (CD; n = 31) or ulcerative colitis (UC; n = 16) who had not responded to 2 previous treatment regimens with antagonists of tumor necrosis factor and were starting therapy with vedolizumab at 2 hospitals in France, from June 2014 through April 2016. All patients were given a 300-mg infusion of vedolizumab at the start of the study, Week 2, Week 6, and then every 8 weeks; patients were also given corticosteroids during the first 4-6 weeks. Patients not in remission at Week 6 were given additional doses of vedolizumab at Week 10 and then every 4 weeks (extended therapy or optimization). Remission at Week 6 of treatment was defined as CD activity score below 150 points for patients with CD and a partial Mayo Clinic score of <3 points, without concomitant corticosteroids, for patients with UC. Blood samples were collected each week and serum levels of vedolizumab and antibodies against vedolizumab were measured using an enzyme-linked immunosorbent assay. Median trough levels of vedolizumab and interquartile ranges were compared using the nonparametric Mann-Whitney test. The primary objective was to determine whether trough levels of vedolizumab measured during the first 6 weeks of induction therapy associated with the need for extended treatment within the first 6 months. Based on response to therapy at Week 6, extended treatment was required for 30 of the 47 patients (23 patients with CD and 7 patients with UC). At Week 2, trough levels of vedolizumab for patients selected for extended treatment were 23.0 μg/mL (interquartile range, 14.0-37.0 μg/mL), compared with 42.5 μg/mL in patients who did not receive extended treatment (interquartile range, 33.5-50.7; P = .15). At Week 6, trough levels of vedolizumab <18.5 μg/mL were associated with need for extended therapy (100% positive predictive value, 46.2%; negative predictive value; area under the receiver operating characteristic curve, 0.72) within the first 6 months. Among patients who required extended treatment at Week 10, all of those with trough levels of vedolizumab <19.0 μg/mL at Week 6 had achieved clinical remission 4 weeks later (secondary responders). In a prospective study of patients with CD or UC receiving induction therapy with vedolizumab, low trough levels of vedolizumab at Week 6 (<19.0 μg/mL) are associated with need for additional doses (given at Week 10 and then every 4 weeks). All patients receiving these additional doses achieved a clinical response 4 weeks later. Copyright © 2017 AGA Institute. Published by Elsevier Inc. All rights reserved.

Exploring Unconventional Hydrocarbons in the Makó Trough, Pannonian basin, Hungary: Results and Challenges

NASA Astrophysics Data System (ADS)

Horvath, Anita; Bada, Gabor; Szafian, Peter; Sztano, Orsolya; Law, Ben; Wallis, Rod

2010-05-01

The latest phase exploration in the Makó Trough, which commenced a few years ago, has focused on the utilization of unconventional hydrocarbons. Accumulations are regarded as "unconventional" when they cannot be produced economically except by means of some sort of stimulation, usually hydraulic fracturing. The model we have developed for the evaluation of the hydrocarbon potential indicates a significant gas accumulation in the area of the Makó Trough. The tally of the distinctive attributes of the hydrocarbon system and the combined analysis of the available geological data led to the conclusion that the Makó Trough represents an area of active basin-centered gas accumulation (BCGA), with very significant perspective reserves. In a BCGA, hydrocarbons do not accumulate conventionally, in structural or stratigraphic traps, but rather in cells. Due to the geological setting of the Makó Trough, the hydrocarbon cell here forms a relatively continuous zone marked by considerable internal lithological and petrophysical variability. The most prolific parts, called sweet spots, possess a reservoir potential higher than the average. The identification of these sweet spots constitutes one of the most important, and quite possibly the most challenging task of the entire exploration project. The hemipelagic Endrőd Formation, which acts as the source rock, contains organic-rich marls in a depth delimited by the 170-230 °C isotherms. These marls constitute the still active hydrocarbon "kitchen" of the BCGA in the Makó Trough. The top and bottom boundaries of the cell essentially coincide with the turbidites of the Szolnok Formation and the top of the pre-Neogene basement, respectively. In light of the fact that pressure, temperature, and maturity tests have produced rather similar results in a number of wells in the area, we have reason to believe that the extension of the Makó Trough's BCGA is of regional dimensions (>1000 km2). The thickness and lateral extension of the potential reservoirs yield a cell volume as great as several hundred km3 - the largest single prospective gas occurrence in Hungary to date. Due to its novelty and complexity, the exploration of this unconventional resource demands the concurrent application of a wider range of geological and geophysical methods. In this presentation, we use selected examples to give an idea of where we stand on the way toward understanding the Makó Trough, particularly in terms of the geometric and structural features of the basin, the depositional (basin-fill) processes, and of the maturation history and accumulation properties of hydrocarbons. The geophysical surveys were purpose-designed to enable the mapping of the deep sedimentary trough and the sediments deposited in it. The data acquired to date suggest that the basin-centered gas accumulation occurred in the Lower Pannonian strata (11-6? Ma). Interpreting the 3D seismic data, the structural features and sedimentology of the basin can be studied in excellent resolution, while the integration of the seismic information with the geological data obtained from the wells allows us to interpret local well information extensively to gain a deeper, three-dimensional understanding of the basin. The sedimentary sequence filling up the Makó Trough displays distinct stratigraphic units separated by unconformities. Mapping the top of the pre-Neogene basement provides valuable insight into the nature of the paleo-geomorphological elements and the sedimentary environment at the onset of rifting. Paleontological information dates the syn-rift sediments of the trough to the Late Miocene (Early Pannonian), suggesting that the most intensive phase of basin evolution here was delayed by a few million years compared to adjacent areas. For the environmental reconstruction of the post-rift sedimentary sequence, we start with the assumption that initially a starved basin existed here, where sedimentation could not keep up with the rate of subsidence (Endrőd Formation). The basin was then almost completely filled by the turbidites of a prograding delta system (Szolnok Formation), followed by the sediments from the pro-delta (Algyő Formation) and the delta plain (Újfalu Formation). During the Plio- and Pleistocene, the area continued to subside at a decreased rate, providing a limited accumulation space filled by a thick sequence of alluvial deposits similar to the paleo-environment of the Tisza River and its tributaries prior to regulation. Our modeling of basin evolution in terms of subsidence, thermal and maturation history based on the results of geochemical, petrophysical, and paleontological investigations reveals that the organic matter accumulated in the trough underwent exceptionally rapid maturation during the last 5 to 7 million years. In fact, source rocks continue to mature at present time, and the hydrocarbons they generate continue to migrate and trap. The rather young age of the Pannonian Basin and its hydrocarbon system makes it quite different from the other examples of basin-centered gas accumulation, such as the classic Rocky Mountains in the U.S., or the Karoo Basin in South Africa, the Beetaloo Basin in Australia, making up the exploration portfolio of Falcon.

Pushing concentration of stationary solar concentrators to the limit.

PubMed

Winston, Roland; Zhang, Weiya

2010-04-26

We give the theoretical limit of concentration allowed by nonimaging optics for stationary solar concentrators after reviewing sun- earth geometry in direction cosine space. We then discuss the design principles that we follow to approach the maximum concentration along with examples including a hollow CPC trough, a dielectric CPC trough, and a 3D dielectric stationary solar concentrator which concentrates sun light four times (4x), eight hours per day year around.

Pushing concentration of stationary solar concentrators to the limit.

PubMed

Winston, Roland; Zhang, Weiya

2010-04-26

We give the theoretical limit of concentration allowed by nonimaging optics for stationary solar concentrators after reviewing sun-earth geometry in direction cosine space. We then discuss the design principles that we follow to approach the maximum concentration along with examples including a hollow CPC trough, a dielectric CPC trough, and a 3D dielectric stationary solar concentrator which concentrates sun light four times (4x), eight hours per day year around.

Exact analytic flux distributions for two-dimensional solar concentrators.

PubMed

Fraidenraich, Naum; Henrique de Oliveira Pedrosa Filho, Manoel; Vilela, Olga C; Gordon, Jeffrey M

2013-07-01

A new approach for representing and evaluating the flux density distribution on the absorbers of two-dimensional imaging solar concentrators is presented. The formalism accommodates any realistic solar radiance and concentrator optical error distribution. The solutions obviate the need for raytracing, and are physically transparent. Examples illustrating the method's versatility are presented for parabolic trough mirrors with both planar and tubular absorbers, Fresnel reflectors with tubular absorbers, and V-trough mirrors with planar absorbers.

Interseismic Coupling-Based Earthquake and Tsunami Scenarios for the Nankai Trough

NASA Astrophysics Data System (ADS)

Baranes, H.; Woodruff, J. D.; Loveless, J. P.; Hyodo, M.

2018-04-01

Theoretical modeling and investigations of recent subduction zone earthquakes show that geodetic estimates of interseismic coupling and the spatial distribution of coseismic rupture are correlated. However, the utility of contemporary coupling in guiding construction of rupture scenarios has not been evaluated on the world's most hazardous faults. Here we demonstrate methods for scaling coupling to slip to create rupture models for southwestern Japan's Nankai Trough. Results show that coupling-based models produce distributions of ground surface deformation and tsunami inundation that are similar to historical and geologic records of the largest known Nankai earthquake in CE 1707 and to an independent, quasi-dynamic rupture model. Notably, these models and records all support focused subsidence around western Shikoku that makes the region particularly vulnerable to flooding. Results imply that contemporary coupling mirrors the slip distribution of a full-margin, 1707-type rupture, and Global Positioning System measurements of surface motion are connected with the trough's physical characteristics.

Gas Forming a V-Shape Aluminum Sheet into a Trough of Saddle-Contour

NASA Astrophysics Data System (ADS)

Lee, Shyong; Lan, Hsien-Chin; Lee, Jye; Wang, Jian-Yih; Huang, J. C.; Chu, Chun Lin

2012-11-01

A sheet metal trough of aluminum alloys is manufactured by gas-forming process at 500 °C. The product with slope walls is of ~1.2 m long and ~260 mm opening width, comprising two conical sinks at two ends. The depth of one sink apex is ~350 mm, which results in the depth/width ratio reaching 1.4. To form such a complex shape with high aspect ratio, a pre-form of V-shape groove is prepared prior to the gas-forming work. When this double concave trough is turned upside down, the convex contour resembles the back of a twin hump camel. The formability of this configuration depends on the gas pressurization rate profile, the working temperature, material's micro-structure, as well as pre-form design. The latter point is demonstrated by comparing two aluminum alloys, AA5182 and SP5083, with nearly same compositions but very different grain sizes.

Chronology of Miocene-Pliocene deposits at Split Mountain Gorge, Southern California: A record of regional tectonics and Colorado River evolution

USGS Publications Warehouse

Dorsey, R.J.; Fluette, A.; McDougall, K.; Housen, B.A.; Janecke, S.U.; Axen, G.J.; Shirvell, C.R.

2007-01-01

Late Miocene to early Pliocene deposit at Split Mountain Gorge, California, preserve a record of basinal response to changes in regional tectonics, paleogeography, and evolution of the Colorado River. The base of the Elephant Trees Formation, magnetostratigraphically dated as 8.1 ?? 0.4 Ma, provides the earliest well-dated record of extension in the southwestern Salton Trough. The oldest marine sediments are ca. 6.3 Ma. The nearly synchronous timing of marine incursion in the Salton Trough and northern Gulf of California region supports a model for localization of Pacific-North America plate motion in the Gulf ca. 6 Ma. The first appearance of Colorado River sand at the Miocene-Pliocene boundary (5.33 Ma) suggests rapid propagation of the river to the Salton Trough, and supports a lake-spillover hypothesis for initiation of the lower Colorado River. ?? 2007 Geological Society of America.

The Valencia trough and the origin of the western Mediterranean basins

NASA Astrophysics Data System (ADS)

Vegas, R.

1992-03-01

Evolutionary models for the Valencia trough must be necessarily related to the Neogene-Present geodynamics of the western Mediterranean basins. All these basins occupy new space created in the wake of the westward translation of the Alboran block and the counter-clockwise rotation of the Corso-Sardinian block. This escape-tectonics, microplate dispersal, model can account for the co-existence and progressive migration of compressional and extensional strain fields within the Africa-Europe broad zone of convergence. In this escape-tectonics model, the Valencia trough has resulted in a complex evolution which includes: (1) latest Oligocene-Early Miocene rifting along the Catalan-Valencian margin due to the opening of the Gulf of Lions; (2) almost simultaneous, Early Miocene, transpressive thrusting in the Balearic margin related to the initiation of displacement of the Alboran block; and (3) Late Miocene generalized extension as a consequence of the opening of the South Balearic basin.

Slide Conveying of Granular Materials-Thinking Out of the Glovebox

NASA Technical Reports Server (NTRS)

Goddard, J. D.; Didwania, A. K.; Nott, P. R.

2000-01-01

The vibratory conveyor, routinely employed for normal-gravity transport of granular materials, usually consists of a continuous open trough vibrated sinusoidally to induce axial movement of a granular material. Motivated in part by a hypothetical application in zero gravity, we propose a novel modification of the vibratory conveyor based on a closed 2d trough operating in a "slide-conveying" mode, with the granular mass remaining permanently in contact with the trough walls. We present a detailed analysis of the mechanics of transport, based on a rigid-slab model for the granular mass with frictional (Coulomb) slip at the upper and lower walls. The form of the vibration cycle plays a crucial role, and the optimal conveying cycle is not the commonly assumed rectilinear sinusoidal motion. The conveying efficiency for the novel slide conveyor will be presented for several simple vibration cycles, including one believed to represent the theoretical optimum.

Plasmaspheric Erosion via Plasmasphere Coupling to Ring Current Plasmas: EUV Observations and Modeling

NASA Technical Reports Server (NTRS)

Adrian, M. L.; Gallagher, D. L.; Khazanov, G. V.; Chsang, S. W.; Liemohn, M. W.; Perez, J. D.; Green, J. L.; Sandel, B. R.; Mitchell, D. G.; Mende, S. B.;

Coincident observations of ionospheric troughs and the equatorial plasmapause

NASA Technical Reports Server (NTRS)

Grebowsky, J. M.; Maynard, N. C.; Tulunay, Y. K.; Lanzerotti, L. J.

1976-01-01

Electron-density observations made in the topside ionosphere by the Ariel 4 and Isis 2 satellites are examined in conjunction with results obtained by Explorer 45 when it traversed the near-equatorial plasmapause with one hour (both UT and MLT) of the Ariel and Isis traversals of the same L coordinate. Both dusk and night observations are analyzed, and an attempt is made to show that depressions in ionospheric electron density occur in the vicinity of the plasmapause field line. It is concluded that the electron distributions observed in the electron-density troughs at 550 km near dusk by Ariel and at 1400 km near midnight by Isis do not always parallel variations in the light-ion distribution inferred from the Explorer plasmapause traversals and that there appears to be no specific feature of the main ionospheric trough which can be used to identify the plasmapause field line except in a statistical sense.

Airborne Lidar measurements of the atmospheric pressure profile with tunable Alexandrite lasers

NASA Technical Reports Server (NTRS)

Korb, C. L.; Schwemmer, G. K.; Dombrowski, M.; Milrod, J.; Walden, H.

1986-01-01

The first remote measurements of the atmospheric pressure profile made from an airborne platform are described. The measurements utilize a differential absorption lidar and tunable solid state Alexandrite lasers. The pressure measurement technique uses a high resolution oxygen A band where the absorption is highly pressure sensitive due to collision broadening. Absorption troughs and regions of minimum absorption were used between pairs of stongly absorption lines for these measurements. The trough technique allows the measurement to be greatly desensitized to the effects of laser frequency instabilities. The lidar system was set up to measure pressure with the on-line laser tuned to the absorption trough at 13147.3/cm and with the reference laser tuned to a nonabsorbing frequency near 13170.0/cm. The lidar signal returns were sampled with a 200 range gate (30 vertical resoltion) and averaged over 100 shots.

Constraining back-arc basin formation in the eastern Coral Sea: preliminary results from the ECOSAT voyage

NASA Astrophysics Data System (ADS)

Seton, M.; Williams, S.; Mortimer, N. N.; Meffre, S.; Moore, J.; Micklethwaite, S.; Zahirovic, S.

2013-12-01

The eastern Coral Sea region is an underexplored area at the northeastern corner of the Australian plate, where long-lived interaction between the Pacific and Australian plate boundaries has resulted in an intricate assemblage of deep oceanic basins and ridges, continental fragments and volcanic products. A paucity of marine geophysical and geological data from this complex region has resulted in the lack of a clear conceptual framework to describe its formation, ultimately affecting our understanding of the connection between the plate boundaries of the SW Pacific and SE Asia. In particular, the tectonic relationship between two back-arc basins, the Santa Cruz and d'Entrecasteaux Basins, and the South Rennell Trough, has yet to be resolved. In October-November, 2012, we collected 6,200 km of marine magnetic, 6,800 km of gravity and over 13,600 km2 of swath bathymetry data from the eastern Coral Sea onboard the RV Southern Surveyor. A complementary dredging program yielded useful samples from 14 seafloor sites. Our preliminary geochemical interpretation of the dredge samples obtained from the South Rennell Trough reveal volcanic rocks resembling MORB or BABB-type basalts, similar in composition to the recently re-analysed and dated ORSTOM dredges from the area that yielded ~28 Ma MORB-like basalts. Swath bathymetry profiles from the Santa Cruz Basin reveal that the South Rennell Trough extends into this basin, with seafloor spreading fabric being parallel to the trough. Preliminary analysis of the three full and four partial new magnetic anomaly profiles across the Santa Cruz Basin, coupled with limited existing profiles, reveals that the basin may have formed between Chrons 13-18 (~32-38 Ma), with an extinct spreading ridge along the inferred continuation of the South Rennell Trough, consistent with ORSTOM age dates. Our results suggest that the South Rennell Trough is an extinct southwestward propagating spreading ridge, which may have initiated along a pre-existing zone of weakness. A preliminary interpretation of the 4 magnetic profiles collected in the d'Entrecasteaux Basin and existing profiles of seafloor fabric shows that this basin does not share a common seafloor spreading history with the Santa Cruz Basin, as has been suggested previously. Our preliminary interpretation of the relationship between the Santa Cruz Basin, South Rennell Trough and d'Entrecasteaux Basin requires a re-interpretation of existing models of the SW Pacific to take into account a southwestward propagating spreading ridge between 38-32 Ma, contemporaneous with seafloor spreading further south in the North Loyalty Basin. Further work on age-dating and geochemical analysis of the newly collected dredge samples and an in-depth analysis of the magnetic anomalies in the d'Entrecasteaux Basin may further yield important information concerning the tectonic evolution of the area.

Unraveling the complexities of circadian and sleep interactions with memory formation through invertebrate research

PubMed Central

Michel, Maximilian; Lyons, Lisa C.

2014-01-01

Across phylogeny, the endogenous biological clock has been recognized as providing adaptive advantages to organisms through coordination of physiological and behavioral processes. Recent research has emphasized the role of circadian modulation of memory in generating peaks and troughs in cognitive performance. The circadian clock along with homeostatic processes also regulates sleep, which itself impacts the formation and consolidation of memory. Thus, the circadian clock, sleep and memory form a triad with ongoing dynamic interactions. With technological advances and the development of a global 24/7 society, understanding the mechanisms underlying these connections becomes pivotal for development of therapeutic treatments for memory disorders and to address issues in cognitive performance arising from non-traditional work schedules. Invertebrate models, such as Drosophila melanogaster and the mollusks Aplysia and Lymnaea, have proven invaluable tools for identification of highly conserved molecular processes in memory. Recent research from invertebrate systems has outlined the influence of sleep and the circadian clock upon synaptic plasticity. In this review, we discuss the effects of the circadian clock and sleep on memory formation in invertebrates drawing attention to the potential of in vivo and in vitro approaches that harness the power of simple invertebrate systems to correlate individual cellular processes with complex behaviors. In conclusion, this review highlights how studies in invertebrates with relatively simple nervous systems can provide mechanistic insights into corresponding behaviors in higher organisms and can be used to outline possible therapeutic options to guide further targeted inquiry. PMID:25136297

High-temperature solar receiver integrated with a short-term storage system

NASA Astrophysics Data System (ADS)

Giovannelli, Ambra; Bashir, Muhammad Anser; Archilei, Erika Maria

2017-06-01

Small-Scale Concentrated Solar Power Plants could have a potential market for off-grid applications in rural contexts with limited access to the electrical grid and favorable environmental characteristics. Some Small-Scale plants have already been developed, like the 25-30 kWe Dish-Stirling engine. Other ones are under development as, for example, plants based on Parabolic Trough Collectors coupled with Organic Rankine Cycles. Furthermore, the technological progress achieved in the development of new small high-temperature solar receiver, makes possible the development of interesting systems based on Micro Gas Turbines coupled with Dish collectors. Such systems could have several advantages in terms of costs, reliability and availability if compared with Dish-Stirling plants. In addition, Dish-Micro Gas Turbine systems are expected to have higher performance than Solar Organic Rankine Cycle plants. The present work focuses the attention on some challenging aspects related to the design of small high-temperature solar receivers for Dish-Micro Gas Turbine systems. Natural fluctuations in the solar radiation can reduce system performance and damage seriously the Micro Gas Turbine. To stabilize the system operation, the solar receiver has to assure a proper thermal inertia. Therefore, a solar receiver integrated with a short-term storage system based on high-temperature phase-change materials is proposed in this paper. Steady-state and transient analyses (for thermal storage charge and discharge phases) have been carried out using the commercial CFD code Ansys-Fluent. Results are presented and discussed.

Two-Dimensional Automatic Measurement for Nozzle Flow Distribution Using Improved Ultrasonic Sensor

PubMed Central

Zhai, Changyuan; Zhao, Chunjiang; Wang, Xiu; Wang, Ning; Zou, Wei; Li, Wei

2015-01-01

Spray deposition and distribution are affected by many factors, one of which is nozzle flow distribution. A two-dimensional automatic measurement system, which consisted of a conveying unit, a system control unit, an ultrasonic sensor, and a deposition collecting dish, was designed and developed. The system could precisely move an ultrasonic sensor above a pesticide deposition collecting dish to measure the nozzle flow distribution. A sensor sleeve with a PVC tube was designed for the ultrasonic sensor to limit its beam angle in order to measure the liquid level in the small troughs. System performance tests were conducted to verify the designed functions and measurement accuracy. A commercial spray nozzle was also used to measure its flow distribution. The test results showed that the relative error on volume measurement was less than 7.27% when the liquid volume was 2 mL in trough, while the error was less than 4.52% when the liquid volume was 4 mL or more. The developed system was also used to evaluate the flow distribution of a commercial nozzle. It was able to provide the shape and the spraying width of the flow distribution accurately. PMID:26501288

Neutropenia is independently associated with sub-therapeutic serum concentration of vancomycin.

PubMed

Choi, Min Hyuk; Choe, Yeon Hwa; Lee, Sang-Guk; Jeong, Seok Hoon; Kim, Jeong-Ho

2017-02-01

We aimed to identify the impact of the presence of neutropenia on serum vancomycin concentration (SVC). A retrospective study was conducted from January 2005 to December 2015. The study population was comprised of adult patients who were performed serum concentration of vancomycin. Patients with renal failure or using non-conventional dosages of vancomycin were excluded. A total of 1307 adult patients were included in this study, of whom 163 (12.4%) were neutropenic. Patients with neutropenia presented significantly lower SVCs than non-neutropenic patients (P<0.0001). Multiple linear regressions showed significant association between neutropenia and trough SVC (beta coefficients, -2.351; P=0.004). Multiple logistic regression analysis also revealed a significant association between sub-therapeutic vancomycin concentrations (trough SVC values<10mg/l) and neutropenia (odds ratio, 1.75, P=0.029) CONCLUSIONS: The presence of neutropenia is significantly associated with low SVC, even after adjusting for other variables. Therefore, neutropenic patients had a higher risk of sub-therapeutic SVC compared with non-neutropenic patients. We recommended that vancomycin therapy should be monitored with TDM-guided optimization of dosage and intervals, especially in neutropenic patients. Copyright © 2016 Elsevier B.V. All rights reserved.