Matsumoto, Naoya; Konno, Alu; Inoue, Takashi; Okazaki, Shigetoshi
2018-06-18
In this paper, excitation light wavefront modulation is performed considering the curved sample surface shape to demonstrate high-quality deep observation using two-photon excitation microscopy (TPM) with a dry objective lens. A large spherical aberration typically occurs when the refractive index (RI) interface between air and the sample is a plane perpendicular to the optical axis. Moreover, the curved sample surface shape and the RI mismatch cause various aberrations, including spherical ones. Consequently, the fluorescence intensity and resolution of the obtained image are degraded in the deep regions. To improve them, we designed a pre-distortion wavefront for correcting the aberration caused by the curved sample surface shape by using a novel, simple optical path length difference calculation method. The excitation light wavefront is modulated to the pre-distortion wavefront by a spatial light modulator incorporated in the TPM system before passing through the interface, where the RI mismatch occurs. Thus, the excitation light is condensed without aberrations. Blood vessels were thereby observed up to an optical depth of 2,000 μm in a cleared mouse brain by using a dry objective lens.
Qiao, Mu; Liu, Honglin; Pang, Guanghui; Han, Shensheng
2017-08-29
Manipulating light non-invasively through inhomogeneous media is an attractive goal in many disciplines. Wavefront shaping and optical phase conjugation can focus light to a point. Transmission matrix method can control light on multiple output modes simultaneously. Here we report a non-invasive approach which enables three-dimension (3D) light control between two turbid layers. A digital optical phase conjugation mirror measured and conjugated the diffused wavefront, which originated from a quasi-point source on the front turbid layer and passed through the back turbid layer. And then, because of memory effect, the phase-conjugated wavefront could be used as a carrier wave to transport a pre-calculated wavefront through the back turbid layer. The pre-calculated wavefront could project a desired 3D light field inside the sample, which, in our experiments, consisted of two 220-grid ground glass plates spaced by a 20 mm distance. The controllable range of light, according to the memory effect, was calculated to be 80 mrad in solid angle and 16 mm on z-axis. Due to the 3D light control ability, our approach may find applications in photodynamic therapy and optogenetics. Besides, our approach can also be combined with ghost imaging or compressed sensing to achieve 3D imaging between turbid layers.
NASA Astrophysics Data System (ADS)
Sarpün, Ismail Hakki; n, Abdullah Aydı; Tel, Eyyup
2017-09-01
In fusion reactors, neutron induced radioactivity strongly depends on the irradiated material. So, a proper selection of structural materials will have been limited the radioactive inventory in a fusion reactor. First-wall and blanket components have high radioactivity concentration due to being the most flux-exposed structures. The main objective of fusion structural material research is the development and selection of materials for reactor components with good thermo-mechanical and physical properties, coupled with low-activation characteristics. Double differential light charged particle emission cross section, which is a fundamental data to determine nuclear heating and material damages in structural fusion material research, for some elements target nuclei have been calculated by the TALYS 1.8 nuclear reaction code at 14-15 MeV neutron incident energy and compared with available experimental data in EXFOR library. Direct, compound and pre-equilibrium reaction contribution have been theoretically calculated and dominant contribution have been determined for each emission of proton, deuteron and alpha particle.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Akkus, Harun, E-mail: physicisthakkus@gmail.com
2013-12-15
We introduce a method for calculating the amount of deflection angle of light passing close to a massive object. It is based on Fermat’s principle. The varying refractive index of medium around the massive object is obtained from the Buckingham pi-theorem. Highlights: •A different and simpler method for the calculation of deflection angle of light. •Not a curved space, only 2-D Euclidean space. •Getting a varying refractive index from the Buckingham pi-theorem. •Obtaining the some results of general relativity from Fermat’s principle.
Brown, Barbara B.; Tribby, Calvin P.; Tharp, Doug; Flick, Kristi; Miller, Harvey J.; Smith, Ken R.; Jensen, Wyatt
2015-01-01
Many communities in the United States have been adding new light rail to bus-predominant public transit systems. However, there is disagreement as to whether opening light rail lines attracts new ridership or merely draws ridership from existing transit users. We study a new light rail line in Salt Lake City, Utah, USA, which is part of a complete street redevelopment. We utilize a pre-test post-test control group quasi-experimental design to test two different measures of ridership change. The first measure is calculated from stops along the light rail route; the second assumes that nearby bus stops might be displaced by the rail and calculates ridership change with those stops included as baseline. Both the simple measure (transit use changes on the complete street light rail corridor) and the “displacement” measure (transit use changes in the one-quarter mile catchment areas around new light rail stops) showed significant (p < .01) and substantial (677%) increases in transit passengers compared to pre-light rail bus users. In particular, the displacement analysis discredits a common challenge that when a new light rail line opens, most passengers are simply former bus riders whose routes were canceled in favor of light rail. The study suggests that light rail services can attract additional ridership to public transit systems. In addition, although pre-post control-group designs require time and effort, this project underscores the benefits of such quasi-experimental designs in terms of the strength of the inferences that can be drawn about the impacts of new transit infrastructure and services. PMID:26543329
Werner, Carol M; Brown, Barbara B; Tribby, Calvin P; Tharp, Doug; Flick, Kristi; Miller, Harvey J; Smith, Ken R; Jensen, Wyatt
2016-01-01
Many communities in the United States have been adding new light rail to bus-predominant public transit systems. However, there is disagreement as to whether opening light rail lines attracts new ridership or merely draws ridership from existing transit users. We study a new light rail line in Salt Lake City, Utah, USA, which is part of a complete street redevelopment. We utilize a pre-test post-test control group quasi-experimental design to test two different measures of ridership change. The first measure is calculated from stops along the light rail route; the second assumes that nearby bus stops might be displaced by the rail and calculates ridership change with those stops included as baseline. Both the simple measure (transit use changes on the complete street light rail corridor) and the "displacement" measure (transit use changes in the one-quarter mile catchment areas around new light rail stops) showed significant ( p < .01) and substantial (677%) increases in transit passengers compared to pre-light rail bus users. In particular, the displacement analysis discredits a common challenge that when a new light rail line opens, most passengers are simply former bus riders whose routes were canceled in favor of light rail. The study suggests that light rail services can attract additional ridership to public transit systems. In addition, although pre-post control-group designs require time and effort, this project underscores the benefits of such quasi-experimental designs in terms of the strength of the inferences that can be drawn about the impacts of new transit infrastructure and services.
Image system for three dimensional, 360{degree}, time sequence surface mapping of moving objects
Lu, S.Y.
1998-12-22
A three-dimensional motion camera system comprises a light projector placed between two synchronous video cameras all focused on an object-of-interest. The light projector shines a sharp pattern of vertical lines (Ronchi ruling) on the object-of-interest that appear to be bent differently to each camera by virtue of the surface shape of the object-of-interest and the relative geometry of the cameras, light projector and object-of-interest. Each video frame is captured in a computer memory and analyzed. Since the relative geometry is known and the system pre-calibrated, the unknown three-dimensional shape of the object-of-interest can be solved for by matching the intersections of the projected light lines with orthogonal epipolar lines corresponding to horizontal rows in the video camera frames. A surface reconstruction is made and displayed on a monitor screen. For 360{degree} all around coverage of the object-of-interest, two additional sets of light projectors and corresponding cameras are distributed about 120{degree} apart from one another. 20 figs.
A Self-consistent Model for a Full Cycle of Recurrent Novae—Wind Mass-loss Rate and X-Ray Luminosity
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kato, Mariko; Saio, Hideyuki; Hachisu, Izumi, E-mail: mariko.kato@hc.st.keio.ac.jp
2017-04-01
An unexpectedly slow evolution in the pre-optical-maximum phase was suggested in the very short recurrence period of nova M31N 2008-12a. To obtain reasonable nova light curves we have improved our calculation method by consistently combining optically thick wind solutions of hydrogen-rich envelopes with white dwarf (WD) structures calculated by a Henyey-type evolution code. The wind mass-loss rate is properly determined with high accuracy. We have calculated light curve models for 1.2 M {sub ⊙} and 1.38 M {sub ⊙} WDs with mass accretion rates corresponding to recurrence periods of 10 yr and 1 yr, respectively. The outburst lasts 590/29 days,more » in which the pre-optical-maximum phase is 82/16 days, for 1.2/1.38 M {sub ⊙}, respectively. Optically thick winds start at the end of the X-ray flash and cease at the beginning of the supersoft X-ray phase. We also present supersoft X-ray light curves including a prompt X-ray flash and later supersoft X-ray phase.« less
"Let There Be Light" Minicourse, Career Oriented Pre-Technical Physics.
ERIC Educational Resources Information Center
Dallas Independent School District, TX.
This instructional guide, intended for student use, develops the concept of light through a series of sequential activities. A technical development of the subject is pursued with examples stressing practical aspects of the concepts. Included in the minicourse are: (1) the rationale, (2) terminal behavioral objectives, (3) enabling behavioral…
Image system for three dimensional, 360 DEGREE, time sequence surface mapping of moving objects
Lu, Shin-Yee
1998-01-01
A three-dimensional motion camera system comprises a light projector placed between two synchronous video cameras all focused on an object-of-interest. The light projector shines a sharp pattern of vertical lines (Ronchi ruling) on the object-of-interest that appear to be bent differently to each camera by virtue of the surface shape of the object-of-interest and the relative geometry of the cameras, light projector and object-of-interest Each video frame is captured in a computer memory and analyzed. Since the relative geometry is known and the system pre-calibrated, the unknown three-dimensional shape of the object-of-interest can be solved for by matching the intersections of the projected light lines with orthogonal epipolar lines corresponding to horizontal rows in the video camera frames. A surface reconstruction is made and displayed on a monitor screen. For 360.degree. all around coverage of theobject-of-interest, two additional sets of light projectors and corresponding cameras are distributed about 120.degree. apart from one another.
Flynn-Evans, Erin E.; Lockley, Steven W.
2016-01-01
Study Objectives: There is currently no questionnaire-based pre-screening tool available to detect non-24-hour sleep-wake rhythm disorder (N24HSWD) among blind patients. Our goal was to develop such a tool, derived from gold standard, objective hormonal measures of circadian entrainment status, for the detection of N24HSWD among those with visual impairment. Methods: We evaluated the contribution of 40 variables in their ability to predict N24HSWD among 127 blind women, classified using urinary 6-sulfatoxymelatonin period, an objective marker of circadian entrainment status in this population. We subjected the 40 candidate predictors to 1,000 bootstrapped iterations of a logistic regression forward selection model to predict N24HSWD, with model inclusion set at the p < 0.05 level. We removed any predictors that were not selected at least 1% of the time in the 1,000 bootstrapped models and applied a second round of 1,000 bootstrapped logistic regression forward selection models to the remaining 23 candidate predictors. We included all questions that were selected at least 10% of the time in the final model. We subjected the selected predictors to a final logistic regression model to predict N24SWD over 1,000 bootstrapped models to calculate the concordance statistic and adjusted optimism of the final model. We used this information to generate a predictive model and determined the sensitivity and specificity of the model. Finally, we applied the model to a cohort of 1,262 blind women who completed the survey, but did not collect urine samples. Results: The final model consisted of eight questions. The concordance statistic, adjusted for bootstrapping, was 0.85. The positive predictive value was 88%, the negative predictive value was 79%. Applying this model to our larger dataset of women, we found that 61% of those without light perception, and 27% with some degree of light perception, would be referred for further screening for N24HSWD. Conclusions: Our model has predictive utility sufficient to serve as a pre-screening questionnaire for N24HSWD among the blind. Citation: Flynn-Evans EE, Lockley SW. A pre-screening questionnaire to predict non-24-hour sleep-wake rhythm disorder (N24HSWD) among the blind. J Clin Sleep Med 2016;12(5):703–710. PMID:26951421
Airborne Laser Polar Nephelometer
NASA Technical Reports Server (NTRS)
Grams, Gerald W.
1973-01-01
A polar nephelometer has been developed at NCAR to measure the angular variation of the intensity of light scattered by air molecules and particles. The system has been designed for airborne measurements using outside air ducted through a 5-cm diameter airflow tube; the sample volume is that which is common to the intersection of a collimated source beam and the detector field of view within the airflow tube. The source is a linearly polarized helium-neon laser beam. The optical system defines a collimated field-of-view (0.5deg half-angle) through a series of diaphragms located behind a I72-mm focal length objective lens. A photomultiplier tube is located immediately behind an aperture in the focal plane of the objective lens. The laser beam is mechanically chopped (on-off) at a rate of 5 Hz; a two-channel pulse counter, synchronized to the laser output, measures the photomultiplier pulse rate with the light beam both on and off. The difference in these measured pulse rates is directly proportional to the intensity of the scattered light from the volume common to the intersection of the laser beam and the detector field-of-view. Measurements can be made at scattering angles from 15deg to 165deg with reference to the direction of propagation of the light beam. Intermediate angles are obtained by selecting the angular increments desired between these extreme angles (any multiple of 0.1deg can be selected for the angular increment; 5deg is used in normal operation). Pulses provided by digital circuits control a stepping motor which sequentially rotates the detector by pre-selected angular increments. The synchronous photon-counting system automatically begins measurement of the scattered-light intensity immediately after the rotation to a new angle has been completed. The instrument has been flown on the NASA Convair 990 airborne laboratory to obtain data on the complex index of refraction of atmospheric aerosols. A particle impaction device is operated simultaneously to collect particles from the same airflow tube used to make the scattered-light measurements. A size distribution function is obtained by analysis of the particles collected by the impaction device. Calculated values of the angular variation of the scattered-light intensity are obtained by applying Mie scattering theory to the observed size distribution function and assuming different values of the complex index of refraction of the particles. The calculated values are then compared with data on the actual variation of the scattered-light intensity obtained with the polar nephelometer. The most probable value of the complex refractive index is that which provides the best fit between the experimental light scattering data and the parameters calculated from the observed size distribution function.
Sub-pixel accuracy thickness calculation of poultry fillets from scattered laser profiles
NASA Astrophysics Data System (ADS)
Jing, Hansong; Chen, Xin; Tao, Yang; Zhu, Bin; Jin, Fenghua
2005-11-01
A laser range imaging system based on the triangulation method was designed and implemented for online high-resolution thickness calculation of poultry fillets. A laser pattern was projected onto the surface of the chicken fillet for calculation of the thickness of the meat. Because chicken fillets are relatively loosely-structured material, a laser light easily penetrates the meat, and scattering occurs both at and under the surface. When laser light is scattered under the surface it is reflected back and further blurs the laser line sharpness. To accurately calculate the thickness of the object, the light transportation has to be considered. In the system, the Bidirectional Reflectance Distribution Function (BSSRDF) was used to model the light transportation and the light pattern reflected into the cameras. BSSRDF gives the reflectance of a target as a function of illumination geometry and viewing geometry. Based on this function, an empirical method has been developed and it has been proven that this method can be used to accurately calculate the thickness of the object from a scattered laser profile. The laser range system is designed as a sub-system that complements the X-ray bone inspection system for non-invasive detection of hazardous materials in boneless poultry meat with irregular thickness.
Finding the average speed of a light-emitting toy car with a smartphone light sensor
NASA Astrophysics Data System (ADS)
Kapucu, Serkan
2017-07-01
This study aims to demonstrate how the average speed of a light-emitting toy car may be determined using a smartphone’s light sensor. The freely available Android smartphone application, ‘AndroSensor’, was used for the experiment. The classroom experiment combines complementary physics knowledge of optics and kinematics to find the average speed of a moving object. The speed of the toy car is found by determining the distance between the light-emitting toy car and the smartphone, and the time taken to travel these distances. To ensure that the average speed of the toy car calculated with the help of the AndroSensor was correct, the average speed was also calculated by analyzing video-recordings of the toy car. The resulting speeds found with these different methods were in good agreement with each other. Hence, it can be concluded that reliable measurements of the average speed of light-emitting objects can be determined with the help of the light sensor of an Android smartphone.
Blood pulsation measurement using cameras operating in visible light: limitations.
Koprowski, Robert
2016-10-03
The paper presents an automatic method for analysis and processing of images from a camera operating in visible light. This analysis applies to images containing the human facial area (body) and enables to measure the blood pulse rate. Special attention was paid to the limitations of this measurement method taking into account the possibility of using consumer cameras in real conditions (different types of lighting, different camera resolution, camera movement). The proposed new method of image analysis and processing was associated with three stages: (1) image pre-processing-allowing for the image filtration and stabilization (object location tracking); (2) main image processing-allowing for segmentation of human skin areas, acquisition of brightness changes; (3) signal analysis-filtration, FFT (Fast Fourier Transformation) analysis, pulse calculation. The presented algorithm and method for measuring the pulse rate has the following advantages: (1) it allows for non-contact and non-invasive measurement; (2) it can be carried out using almost any camera, including webcams; (3) it enables to track the object on the stage, which allows for the measurement of the heart rate when the patient is moving; (4) for a minimum of 40,000 pixels, it provides a measurement error of less than ±2 beats per minute for p < 0.01 and sunlight, or a slightly larger error (±3 beats per minute) for artificial lighting; (5) analysis of a single image takes about 40 ms in Matlab Version 7.11.0.584 (R2010b) with Image Processing Toolbox Version 7.1 (R2010b).
NASA Astrophysics Data System (ADS)
Chatterjee, Subhasri; Das, Nandan K.; Kumar, Satish; Mohapatra, Sonali; Pradhan, Asima; Panigrahi, Prasanta K.; Ghosh, Nirmalya
2013-02-01
Multi-resolution analysis on the spatial refractive index inhomogeneities in the connective tissue regions of human cervix reveals clear signature of multifractality. We have thus developed an inverse analysis strategy for extraction and quantification of the multifractality of spatial refractive index fluctuations from the recorded light scattering signal. The method is based on Fourier domain pre-processing of light scattering data using Born approximation, and its subsequent analysis through Multifractal Detrended Fluctuation Analysis model. The method has been validated on several mono- and multi-fractal scattering objects whose self-similar properties are user controlled and known a-priori. Following successful validation, this approach has initially been explored for differentiating between different grades of precancerous human cervical tissues.
A Study on AR 3D Objects Shading Method Using Electronic Compass Sensor
NASA Astrophysics Data System (ADS)
Jung, Sungmo; Kim, Seoksoo
More effective communications can be offered to users by applying NPR (Non-Photorealistic Rendering) methods to 3D graphics. Thus, there has been much research on how to apply NPR to mobile contents. However, previous studies only propose cartoon rendering for pre-treatment with no consideration for directions of light in the surrounding environment. In this study, therefore, ECS(Electronic Compass Sensor) is applied to AR 3D objects shading in order to define directions of light as per time slots for assimilation with the surrounding environment.
The application of laser triangulation method on the blind guidance
NASA Astrophysics Data System (ADS)
Wu, Jih-Huah; Wang, Jinn-Der; Fang, Wei; Shan, Yi-Chia; Ma, Shih-Hsin; Kao, Hai-Ko; Jiang, Joe-Air; Lee, Yun-Parn
2011-08-01
A new apparatus for blind-guide is proposed in this paper. Optical triangulation method was used to realize the system. The main components comprise a notebook computer, a camera and two laser modules. One laser module emits a light line beam on the vertical axis. Another laser module emits a light line beam on the tilt horizontal axis. The track of the light line beam on the ground or on the object is captured by the camera, and the image is sent to the notebook computer for calculation. The system can calculate the object width and the distance between the object and the blind in terms of the light line positions on the image. Based on the experiment, the distance between the test object and the blind can be measured with a standard deviation of less than 3% within the range of 60 to 150 cm. The test object width can be measured with a standard deviation of less than 1% within the range of 60 to 150 cm. For saving the power consumption, the laser modules are switched on/off with a trigger pulse. And for reducing the complex computation, the two laser modules are switched on alternately. Besides this, a band pass filter is used to filter out the signal except the specific laser light, which can increase the signal to noise ratio.
Pre-Packaged Commercial PACE Financing Solutions
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wallander, Michael
The objective of this project was to demonstrate a more streamlined method for facilitating commercial property assessed clean energy (PACE) retrofits. The Recipient aimed to prove that energy efficiency performance of simple, pre-packaged technologies (e.g., lighting and heating, ventilation and air conditioning (HVAC)) can be accurately estimated without the need for a detailed energy audit. A successful project would inspire consumer confidence in undertaking cost-effective retrofits.
NASA Astrophysics Data System (ADS)
Schroeder, Walter; Schulze, Wolfram; Wetter, Thomas; Chen, Chi-Hsien
2008-08-01
Three-dimensional (3D) body surface reconstruction is an important field in health care. A popular method for this purpose is laser scanning. However, using Photometric Stereo (PS) to record lumbar lordosis and the surface contour of the back poses a viable alternative due to its lower costs and higher flexibility compared to laser techniques and other methods of three-dimensional body surface reconstruction. In this work, we extended the traditional PS method and proposed a new method for obtaining surface and volume data of a moving object. The principle of traditional Photometric Stereo uses at least three images of a static object taken under different light sources to obtain 3D information of the object. Instead of using normal light, the light sources in the proposed method consist of the RGB-Color-Model's three colors: red, green and blue. A series of pictures taken with a video camera can now be separated into the different color channels. Each set of the three images can then be used to calculate the surface normals as a traditional PS. This method waives the requirement that the object imaged must be kept still as in almost all the other body surface reconstruction methods. By putting two cameras opposite to a moving object and lighting the object with the colored light, the time-varying surface (4D) data can easily be calculated. The obtained information can be used in many medical fields such as rehabilitation, diabetes screening or orthopedics.
NASA Technical Reports Server (NTRS)
Ross, C. L.
1973-01-01
Information necessary for successful performance of the observer's function in the White Light Coronagraph portion of the Apollo Telescope Mount experiments is presented. The pre-flight, in-flight, and post-flight operations required to perform the S-052 experiment are described. A discussion of the scientific objectives of the experiment and a description of the hardware are provided.
Effects of oxytocin on background anxiety in rats with high or low baseline startle
Ayers, Luke; Agostini, Andrew; Schulkin, Jay; Rosen, Jeffrey B.
2016-01-01
Rationale Oxytocin has antianxiety properties in humans and rodents. However, the antianxiety effects have been variable. Objectives To reduce variability and strengthen to the antianxiety effect of oxytocin in fear-potentiated startle, two experiments were performed. First, different amounts of light-shock pairings were given to determine the optimal levels of cue-specific fear conditioning and non-predictable startle (background anxiety). Second, the antianxiety effects of oxytocin were examined in rats with high and low pre-fear conditioning baseline startle to determine if oxytocin differentially affects high and low trait anxiety rats. Methods Baseline pre-fear conditioning startle responses were first measured. Rats then received 1, 5 or 10 light-shock pairings. Fear-potentiated startle was then tested with two trial types: light-cued startle and non-cued startle trials. In the second experiment, rats fear conditioned with 10 light-shock pairings were administered either saline or oxytocin before a fear-potentiated startle test. Rats were categorized as low or high startlers by their pre-fear conditioning startle amplitude. Results Ten shock-pairings produced the largest non-cued startle responses (background anxiety), without increasing cue-specific fear-potentiated startle compared to 1 and 5 light-shock pairings. Cue-specific fear-potentiated startle was unaffected by oxytocin. Oxytocin reduced background anxiety only in rats with low pre-fear startle responses. Conclusions Oxytocin has population selective antianxiety effects on non-cued unpredictable threat, but only in rats with low pre-fear baseline startle responses. The low startle responses are reminiscent of humans with low startle responses and high trait anxiety. PMID:27004789
Light-ion Production from O, Si, Fe and Bi Induced by 175 MeV Quasi-monoenergetic Neutrons
NASA Astrophysics Data System (ADS)
Bevilacqua, R.; Pomp, S.; Jansson, K.; Gustavsson, C.; Österlund, M.; Simutkin, V.; Hayashi, M.; Hirayama, S.; Naitou, Y.; Watanabe, Y.; Hjalmarsson, A.; Prokofiev, A.; Tippawan, U.; Lecolley, F.-R.; Marie, N.; Leray, S.; David, J.-C.; Mashnik, S.
2014-05-01
We have measured double-differential cross sections in the interaction of 175 MeV quasi-monoenergetic neutrons with O, Si, Fe and Bi. We have compared these results with model calculations with INCL4.5-Abla07, MCNP6 and TALYS-1.2. We have also compared our data with PHITS calculations, where the pre-equilibrium stage of the reaction was accounted respectively using the JENDL/HE-2007 evaluated data library, the quantum molecular dynamics model (QMD) and a modified version of QMD (MQMD) to include a surface coalescence model. The most crucial aspect is the formation and emission of composite particles in the pre-equilibrium stage.
Metz, A J; Klein, S D; Scholkmann, F; Wolf, U
2017-01-01
We are increasingly exposed to colored light, but its impact on human physiology is not yet extensively investigated. In the present study we aimed to determine the effects of colored light on human cerebral Mayer wave activity (MWA). We measured oxy- ([O 2 Hb]), deoxy- ([HHb]), total hemoglobin ([tHb]) concentrations and tissue oxygen saturation (StO 2 ) by functional near-infrared spectroscopy (fNIRS) in the left and right pre-frontal cortex (L-PFC, R-PFC) of 17 subjects (median age: 29 years, 6 women). In a randomized crossover design subjects were exposed to blue, red, green, and yellow LED light for 10 min. Pre-light (8 min, baseline) and post-light (15 min, recovery) conditions were darkness. MWA was calculated from band-pass filtered fNIRS signals (~0.08-0.12 Hz). The medians from the last 3 min of each period (baseline, light exposure, recovery) were statistically analyzed. MWA was increased during red and green light vs. baseline and after blue light exposure in recovery in the L-PFC. MWA differed depending on the chosen frequency range, filter design, and type of signals to analyze (raw intensity, hemoglobin signal from multi-distance method or modified Beer-Lambert law, or within hemoglobin signals).
The application of digital image plane holography technology to identify Chinese herbal medicine
NASA Astrophysics Data System (ADS)
Wang, Huaying; Guo, Zhongjia; Liao, Wei; Zhang, Zhihui
2012-03-01
In this paper, the imaging technology of digital image plane holography to identify the Chinese herbal medicine is studied. The optical experiment system of digital image plane holography which is the special case of pre-magnification digital holography was built. In the record system, one is an object light by using plane waves which illuminates the object, and the other one is recording hologram by using spherical light wave as reference light. There is a Micro objective lens behind the object. The second phase factor which caus ed by the Micro objective lens can be eliminated by choosing the proper position of the reference point source when digital image plane holography is recorded by spherical light. In this experiment, we use the Lygodium cells and Onion cells as the object. The experiment results with Lygodium cells and Onion cells show that digital image plane holography avoid the process of finding recording distance by using auto-focusing approach, and the phase information of the object can be reconstructed more accurately. The digital image plane holography is applied to the microscopic imaging of cells more effectively, and it is suit to apply for the identify of Chinese Herbal Medicine. And it promotes the application of digital holographic in practice.
Visual perception enhancement for detection of cancerous oral tissue by multi-spectral imaging
NASA Astrophysics Data System (ADS)
Wang, Hsiang-Chen; Tsai, Meng-Tsan; Chiang, Chun-Ping
2013-05-01
Color reproduction systems based on the multi-spectral imaging technique (MSI) for both directly estimating reflection spectra and direct visualization of oral tissues using various light sources are proposed. Images from three oral cancer patients were taken as the experimental samples, and spectral differences between pre-cancerous and normal oral mucosal tissues were calculated at three time points during 5-aminolevulinic acid photodynamic therapy (ALA-PDT) to analyze whether they were consistent with disease processes. To check the successful treatment of oral cancer with ALA-PDT, oral cavity images by swept source optical coherence tomography (SS-OCT) are demonstrated. This system can also reproduce images under different light sources. For pre-cancerous detection, the oral images after the second ALA-PDT are assigned as the target samples. By using RGB LEDs with various correlated color temperatures (CCTs) for color difference comparison, the light source with a CCT of about 4500 K was found to have the best ability to enhance the color difference between pre-cancerous and normal oral mucosal tissues in the oral cavity. Compared with the fluorescent lighting commonly used today, the color difference can be improved by 39.2% from 16.5270 to 23.0023. Hence, this light source and spectral analysis increase the efficiency of the medical diagnosis of oral cancer and aid patients in receiving early treatment.
DI NARDO, W.; GIANNANTONIO, S.; DI GIUDA, D.; DE CORSO, E.; SCHINAIA, L.; PALUDETTI, G.
2013-01-01
SUMMARY Pre-surgery evaluation, indications for cochlear implantation and expectations in terms of post-operative functional results remain challenging topics in pre-lingually deaf adults. Our study has the purpose of determining the benefits of Single Photon Emission Tomography (SPECT) assessment in pre-surgical evaluation of pre-lingually deaf adults who are candidates for cochlear implantation. In 7 pre-lingually profoundly deaf patients, brain SPECT was performed at baseline conditions and in bilateral simultaneous multi-frequency acoustic stimulation. Six sagittal tomograms of both temporal cortices were used for semi-quantitative analysis in each patient. Percentage increases in cortical perfusion resulting from auditory stimulation were calculated. The results showed an inter-hemispherical asymmetry of the activation extension and intensity in the stimulated temporal areas. Consistent with the obtained brain activation data, patients were implanted preferring the side that showed higher activation after acoustic stimulus. Considering the increment in auditory perception performances, it was possible to point out a relationship between cortical brain activity shown by SPECT and hearing performances, and, even more significant, a correlation between post-operative functional performances and the activation of the most medial part of the sagittal temporal tomograms, corresponding to medium-high frequencies. In light of these findings, we believe that brain SPECT could be considered in the evaluation of deaf patients candidate for cochlear implantation, and that it plays a major role in functional assessment of the auditory cortex of pre-lingually deaf subjects, even if further studies are necessary to conclusively establish its utility. Further developments of this technique are possible by using trans-tympanic electrical stimulation of the cochlear promontory, which could give the opportunity to study completely deaf patients, whose evaluation is objectively difficult with current audiological methods. PMID:23620636
Method and Apparatus for Improved Spatial Light Modulation
NASA Technical Reports Server (NTRS)
Soutar, Colin (Inventor); Juday, Richard D. (Inventor)
2000-01-01
A method and apparatus for modulating a light beam in an optical processing system is described. Preferably, an electrically-controlled polarizer unit and/or an analyzer unit are utilized in combination with a spatial light modulator and a controller. Preferably, the spatial light modulator comprises a pixelated birefringent medium such as a liquid crystal video display. The combination of the electrically controlled polarizer unit and analyzer unit make it simple and fast to reconfigure the modulation described by the Jones matrix of the spatial light modulator. A particular optical processing objective is provided to the controller. The controller performs calculations and supplies control signals to the polarizer unit, the analyzer unit, and the spatial light modulator in order to obtain the optical processing objective.
Method and Apparatus for Improved Spatial Light Modulation
NASA Technical Reports Server (NTRS)
Colin, Soutar (Inventor); Juday, Richard D. (Inventor)
1999-01-01
A method and apparatus for modulating a light beam in an optical processing system is described. Preferably, an electrically-controlled polarizer unit and/or an analyzer unit are utilized in combination with a spatial light modulator and a controller. Preferably, the spatial light modulator comprises a pixelated birefringent medium such as a liquid crystal video display. The combination of the electrically controlled polarizer unit and analyzer unit make it simple and fast to reconfigure the modulation described by the Jones matrix of the spatial light modulator. A particular optical processing objective is provided to the controller. The controller performs calculations and supplies control signals to the polarizer unit, the analyzer unit, and the spatial light modulator in order to obtain die optical processing objective.
The AAO fiber instrument data simulator
NASA Astrophysics Data System (ADS)
Goodwin, Michael; Farrell, Tony; Smedley, Scott; Heald, Ron; Heijmans, Jeroen; De Silva, Gayandhi; Carollo, Daniela
2012-09-01
The fiber instrument data simulator is an in-house software tool that simulates detector images of fiber-fed spectrographs developed by the Australian Astronomical Observatory (AAO). In addition to helping validate the instrument designs, the resulting simulated images are used to develop the required data reduction software. Example applications that have benefited from the tool usage are the HERMES and SAMI instrumental projects for the Anglo-Australian Telescope (AAT). Given the sophistication of these projects an end-to-end data simulator that accurately models the predicted detector images is required. The data simulator encompasses all aspects of the transmission and optical aberrations of the light path: from the science object, through the atmosphere, telescope, fibers, spectrograph and finally the camera detectors. The simulator runs under a Linux environment that uses pre-calculated information derived from ZEMAX models and processed data from MATLAB. In this paper, we discuss the aspects of the model, software, example simulations and verification.
NASA Astrophysics Data System (ADS)
Zoller, Christian; Hohmann, Ansgar; Ertl, Thomas; Kienle, Alwin
2017-07-01
The Monte Carlo method is often referred as the gold standard to calculate the light propagation in turbid media [1]. Especially for complex shaped geometries where no analytical solutions are available the Monte Carlo method becomes very important [1, 2]. In this work a Monte Carlo software is presented, to simulate the light propagation in complex shaped geometries. To improve the simulation time the code is based on OpenCL such that graphics cards can be used as well as other computing devices. Within the software an illumination concept is presented to realize easily all kinds of light sources, like spatial frequency domain (SFD), optical fibers or Gaussian beam profiles. Moreover different objects, which are not connected to each other, can be considered simultaneously, without any additional preprocessing. This Monte Carlo software can be used for many applications. In this work the transmission spectrum of a tooth and the color reconstruction of a virtual object are shown, using results from the Monte Carlo software.
Shading of a computer-generated hologram by zone plate modulation.
Kurihara, Takayuki; Takaki, Yasuhiro
2012-02-13
We propose a hologram calculation technique that enables reconstructing a shaded three-dimensional (3D) image. The amplitude distributions of zone plates, which generate the object points that constitute a 3D object, were two-dimensionally modulated. Two-dimensional (2D) amplitude modulation was determined on the basis of the Phong reflection model developed for computer graphics, which considers the specular, diffuse, and ambient reflection light components. The 2D amplitude modulation added variable and constant modulations: the former controlled the specular light component and the latter controlled the diffuse and ambient components. The proposed calculation technique was experimentally verified. The reconstructed image showed specular reflection that varied depending on the viewing position.
Shadow Detection Based on Regions of Light Sources for Object Extraction in Nighttime Video
Lee, Gil-beom; Lee, Myeong-jin; Lee, Woo-Kyung; Park, Joo-heon; Kim, Tae-Hwan
2017-01-01
Intelligent video surveillance systems detect pre-configured surveillance events through background modeling, foreground and object extraction, object tracking, and event detection. Shadow regions inside video frames sometimes appear as foreground objects, interfere with ensuing processes, and finally degrade the event detection performance of the systems. Conventional studies have mostly used intensity, color, texture, and geometric information to perform shadow detection in daytime video, but these methods lack the capability of removing shadows in nighttime video. In this paper, a novel shadow detection algorithm for nighttime video is proposed; this algorithm partitions each foreground object based on the object’s vertical histogram and screens out shadow objects by validating their orientations heading toward regions of light sources. From the experimental results, it can be seen that the proposed algorithm shows more than 93.8% shadow removal and 89.9% object extraction rates for nighttime video sequences, and the algorithm outperforms conventional shadow removal algorithms designed for daytime videos. PMID:28327515
Reflective and refractive objects for mixed reality.
Knecht, Martin; Traxler, Christoph; Winklhofer, Christoph; Wimmer, Michael
2013-04-01
In this paper, we present a novel rendering method which integrates reflective or refractive objects into a differential instant radiosity (DIR) framework usable for mixed-reality (MR) applications. This kind of objects are very special from the light interaction point of view, as they reflect and refract incident rays. Therefore they may cause high-frequency lighting effects known as caustics. Using instant-radiosity (IR) methods to approximate these high-frequency lighting effects would require a large amount of virtual point lights (VPLs) and is therefore not desirable due to real-time constraints. Instead, our approach combines differential instant radiosity with three other methods. One method handles more accurate reflections compared to simple cubemaps by using impostors. Another method is able to calculate two refractions in real-time, and the third method uses small quads to create caustic effects. Our proposed method replaces parts in light paths that belong to reflective or refractive objects using these three methods and thus tightly integrates into DIR. In contrast to previous methods which introduce reflective or refractive objects into MR scenarios, our method produces caustics that also emit additional indirect light. The method runs at real-time frame rates, and the results show that reflective and refractive objects with caustics improve the overall impression for MR scenarios.
Single-pixel non-imaging object recognition by means of Fourier spectrum acquisition
NASA Astrophysics Data System (ADS)
Chen, Huichao; Shi, Jianhong; Liu, Xialin; Niu, Zhouzhou; Zeng, Guihua
2018-04-01
Single-pixel imaging has emerged over recent years as a novel imaging technique, which has significant application prospects. In this paper, we propose and experimentally demonstrate a scheme that can achieve single-pixel non-imaging object recognition by acquiring the Fourier spectrum. In an experiment, a four-step phase-shifting sinusoid illumination light is used to irradiate the object image, the value of the light intensity is measured with a single-pixel detection unit, and the Fourier coefficients of the object image are obtained by a differential measurement. The Fourier coefficients are first cast into binary numbers to obtain the hash value. We propose a new method of perceptual hashing algorithm, which is combined with a discrete Fourier transform to calculate the hash value. The hash distance is obtained by calculating the difference of the hash value between the object image and the contrast images. By setting an appropriate threshold, the object image can be quickly and accurately recognized. The proposed scheme realizes single-pixel non-imaging perceptual hashing object recognition by using fewer measurements. Our result might open a new path for realizing object recognition with non-imaging.
Perturbation theory in light-cone quantization
DOE Office of Scientific and Technical Information (OSTI.GOV)
Langnau, A.
1992-01-01
A thorough investigation of light-cone properties which are characteristic for higher dimensions is very important. The easiest way of addressing these issues is by analyzing the perturbative structure of light-cone field theories first. Perturbative studies cannot be substituted for an analysis of problems related to a nonperturbative approach. However, in order to lay down groundwork for upcoming nonperturbative studies, it is indispensable to validate the renormalization methods at the perturbative level, i.e., to gain control over the perturbative treatment first. A clear understanding of divergences in perturbation theory, as well as their numerical treatment, is a necessary first step towardsmore » formulating such a program. The first objective of this dissertation is to clarify this issue, at least in second and fourth-order in perturbation theory. The work in this dissertation can provide guidance for the choice of counterterms in Discrete Light-Cone Quantization or the Tamm-Dancoff approach. A second objective of this work is the study of light-cone perturbation theory as a competitive tool for conducting perturbative Feynman diagram calculations. Feynman perturbation theory has become the most practical tool for computing cross sections in high energy physics and other physical properties of field theory. Although this standard covariant method has been applied to a great range of problems, computations beyond one-loop corrections are very difficult. Because of the algebraic complexity of the Feynman calculations in higher-order perturbation theory, it is desirable to automatize Feynman diagram calculations so that algebraic manipulation programs can carry out almost the entire calculation. This thesis presents a step in this direction. The technique we are elaborating on here is known as light-cone perturbation theory.« less
A programmable light engine for quantitative single molecule TIRF and HILO imaging.
van 't Hoff, Marcel; de Sars, Vincent; Oheim, Martin
2008-10-27
We report on a simple yet powerful implementation of objective-type total internal reflection fluorescence (TIRF) and highly inclined and laminated optical sheet (HILO, a type of dark-field) illumination. Instead of focusing the illuminating laser beam to a single spot close to the edge of the microscope objective, we are scanning during the acquisition of a fluorescence image the focused spot in a circular orbit, thereby illuminating the sample from various directions. We measure parameters relevant for quantitative image analysis during fluorescence image acquisition by capturing an image of the excitation light distribution in an equivalent objective backfocal plane (BFP). Operating at scan rates above 1 MHz, our programmable light engine allows directional averaging by circular spinning the spot even for sub-millisecond exposure times. We show that restoring the symmetry of TIRF/HILO illumination reduces scattering and produces an evenly lit field-of-view that affords on-line analysis of evanescnt-field excited fluorescence without pre-processing. Utilizing crossed acousto-optical deflectors, our device generates arbitrary intensity profiles in BFP, permitting variable-angle, multi-color illumination, or objective lenses to be rapidly exchanged.
The effects of acute pesticide exposure on neuroblastoma cells chronically exposed to diazinon.
Axelrad, J C; Howard, C V; McLean, W G
2003-03-14
Speculation about potential neurotoxicity due to chronic exposure to low doses of organophosphate (OP) pesticides is not yet supported by experimental evidence. The objective of this work was to use a cell culture model of chronic OP exposure to determine if such exposure can alter the sensitivity of nerve cells to subsequent acute exposure to OPs or other compounds. NB2a neuroblastoma cells were grown in the presence of 25 microM diazinon for 8 weeks. The OP was then withdrawn and the cells were induced to differentiate in the presence of various other pesticides or herbicides, including OPs and OP-containing formulations. The resulting outgrowth of neurite-like structures was measured by light microscopy and quantitative image analysis and the IC(50) for each OP or formulation was calculated. The IC(50) values in diazinon-pre-exposed cells were compared with the equivalent values in cells not pre-exposed to diazinon. The IC(50) for inhibition of neurite outgrowth by acute application of diazinon, pyrethrum, glyphosate or a commercial formulation of glyphosate was decreased by between 20 and 90% after pre-treatment with diazinon. In contrast, the IC(50) for pirimiphos methyl was unaffected and those for phosmet or chlorpyrifos were increased by between 1.5- and 3-fold. Treatment of cells with chlorpyrifos or with a second glyphosate-containing formulation led to the formation of abnormal neurite-like structures in diazinon-pre-exposed cells. The data support the view that chronic exposure to an OP may reduce the threshold for toxicity of some, but by no means all, environmental agents.
Qu, Yufu; Zou, Zhaofan
2017-10-16
Photographic images taken in foggy or hazy weather (hazy images) exhibit poor visibility and detail because of scattering and attenuation of light caused by suspended particles, and therefore, image dehazing has attracted considerable research attention. The current polarization-based dehazing algorithms strongly rely on the presence of a "sky area", and thus, the selection of model parameters is susceptible to external interference of high-brightness objects and strong light sources. In addition, the noise of the restored image is large. In order to solve these problems, we propose a polarization-based dehazing algorithm that does not rely on the sky area ("non-sky"). First, a linear polarizer is used to collect three polarized images. The maximum- and minimum-intensity images are then obtained by calculation, assuming the polarization of light emanating from objects is negligible in most scenarios involving non-specular objects. Subsequently, the polarization difference of the two images is used to determine a sky area and calculate the infinite atmospheric light value. Next, using the global features of the image, and based on the assumption that the airlight and object radiance are irrelevant, the degree of polarization of the airlight (DPA) is calculated by solving for the optimal solution of the correlation coefficient equation between airlight and object radiance; the optimal solution is obtained by setting the right-hand side of the equation to zero. Then, the hazy image is subjected to dehazing. Subsequently, a filtering denoising algorithm, which combines the polarization difference information and block-matching and 3D (BM3D) filtering, is designed to filter the image smoothly. Our experimental results show that the proposed polarization-based dehazing algorithm does not depend on whether the image includes a sky area and does not require complex models. Moreover, the dehazing image except specular object scenarios is superior to those obtained by Tarel, Fattal, Ren, and Berman based on the criteria of no-reference quality assessment (NRQA), blind/referenceless image spatial quality evaluator (BRISQUE), blind anistropic quality index (AQI), and e.
2006-09-30
dealing with the bleaching of corals and foraminifera and the photosynthesis of benthic plants. OBJECTIVES The initial objective of this work...of the structural light field around coral heads and other vertical structures should be included in future studies of bleaching of coral and... coral bleaching –Perceptibility problem begun for AUV @2m and @8m above 10m bottom –Higher resolution and higher-speed calculations (e.g. more
Video sensor with range measurement capability
NASA Technical Reports Server (NTRS)
Howard, Richard T. (Inventor); Briscoe, Jeri M. (Inventor); Corder, Eric L. (Inventor); Broderick, David J. (Inventor)
2008-01-01
A video sensor device is provided which incorporates a rangefinder function. The device includes a single video camera and a fixed laser spaced a predetermined distance from the camera for, when activated, producing a laser beam. A diffractive optic element divides the beam so that multiple light spots are produced on a target object. A processor calculates the range to the object based on the known spacing and angles determined from the light spots on the video images produced by the camera.
Effects of Circadian Disruption on Methamphetamine Consumption in Methamphetamine-Exposed Rats
Doyle, Susan E.; Feng, Hanting; Garber, Garrett; Menaker, Michael; Lynch, Wendy J.
2015-01-01
Rationale A substantial number of clinical studies indicate associations between sleep abnormalities and drug abuse; however, the role played by the circadian system in the development of addiction is largely unknown. Objective The aim of this study was to examine the effects of experimentally induced chronic jet lag on methamphetamine consumption in a rat model of methamphetamine drinking. Methods Male Sprague-Dawley rats (n=32) were housed in running wheel cages in a 12:12 light:dark cycle. One group of rats (n=16) was given two weeks of forced methamphetamine consumption (0.01% in drinking water; meth pre-exposed) while a second group (n=16, not pre-exposed) received water only. This was followed by a two week abstinence period during which half of the animals from each group were exposed to 4 consecutive 6-hr advancing phase shifts of the light:dark cycle, while the other half remained on the original light:dark cycle. Methamphetamine consumption was assessed in all rats following the deprivation period using a two-bottle choice paradigm. Results Methamphetamine consumption was initially lower in methamphetamine pre-exposed vs. not pre-exposed rats. However, during the second week following abstinence, consumption was significantly higher in phase shifted rats of the methamphetamine pre-exposed group compared to all other groups. Conclusions These data reveal an effect of circadian rhythm disturbance on methamphetamine consumption, and suggest that dysregulation of the circadian system be considered in the etiology of relapse and addiction. PMID:25543849
DOE Office of Scientific and Technical Information (OSTI.GOV)
Radhakrishnan, Archana, E-mail: anju.archana@gmail.com; Murugesan, Dr V., E-mail: murugesh@serc.iisc.in
The electromagnetic theory of light explains the behavior of light in most of the domains quite accurately. The problem arises when the exact solution of the Maxwell's equation is not present, in case of objects with arbitrary geometry. To find the extinction cross-section and lifetime of the gold nanoparticle, the software FDTD solutions 8.6 by Lumerical is employed. The extinction cross-sections and lifetimes of Gold nanospheres of different sizes and arrangements are studied using pulse lengths of the order of femtoseconds. The decay constant and other properties are compared. Further, the lifetimes are calculated using frequency and time domain calculations.
The peculiar dipping events in the disc-bearing young-stellar object EPIC 204278916
NASA Astrophysics Data System (ADS)
Scaringi, S.; Manara, C. F.; Barenfeld, S. A.; Groot, P. J.; Isella, A.; Kenworthy, M. A.; Knigge, C.; Maccarone, T. J.; Ricci, L.; Ansdell, M.
2016-12-01
EPIC 204278916 has been serendipitously discovered from its K2 light curve that displays irregular dimmings of up to 65 per cent for ≈25 consecutive days out of 78.8 d of observations. For the remaining duration of the observations, the variability is highly periodic and attributed to stellar rotation. The star is a young, low-mass (M-type) pre-main-sequence star with clear evidence of a resolved tilted disc from Atacama Large Millimeter/submillimeter Array (ALMA) observations. We examine the K2 light curve in detail and hypothesize that the irregular dimmings are caused by either a warped inner disc edge or transiting cometary-like objects in either circular or eccentric orbits. The explanations discussed here are particularly relevant for other recently discovered young objects with similar absorption dips.
Logvinenko, Alexander D; Funt, Brian; Mirzaei, Hamidreza; Tokunaga, Rumi
2015-01-01
Colour constancy needs to be reconsidered in light of the limits imposed by metamer mismatching. Metamer mismatching refers to the fact that two objects reflecting metameric light under one illumination may reflect non-metameric light under a second; so two objects appearing as having the same colour under one illuminant can appear as having different colours under a second. Yet since Helmholtz, object colour has generally been believed to remain relatively constant. The deviations from colour constancy registered in experiments are usually thought to be small enough that they do not contradict the notion of colour constancy. However, it is important to determine how the deviations from colour constancy relate to the limits metamer mismatching imposes on constancy. Hence, we calculated metamer mismatching's effect for the 20 Munsell papers and 8 pairs of illuminants employed in the colour constancy study by Logvinenko and Tokunaga and found it to be so extensive that the two notions-metamer mismatching and colour constancy-must be mutually exclusive. In particular, the notion of colour constancy leads to some paradoxical phenomena such as the possibility of 20 objects having the same colour under chromatic light dispersing into a hue circle of colours under neutral light. Thus, colour constancy refers to a phenomenon, which because of metamer mismatching, simply cannot exist. Moreover, it obscures the really important visual phenomenon; namely, the alteration of object colours induced by illumination change. We show that colour is not an independent, intrinsic attribute of an object, but rather an attribute of an object/light pair, and then define a concept of material colour in terms of equivalence classes of such object/light pairs. We suggest that studying the shift in material colour under a change in illuminant will be more fruitful than pursuing colour constancy's false premise that colour is an intrinsic attribute of an object.
Single-shot three-dimensional reconstruction based on structured light line pattern
NASA Astrophysics Data System (ADS)
Wang, ZhenZhou; Yang, YongMing
2018-07-01
Reconstruction of the object by single-shot is of great importance in many applications, in which the object is moving or its shape is non-rigid and changes irregularly. In this paper, we propose a single-shot structured light 3D imaging technique that calculates the phase map from the distorted line pattern. This technique makes use of the image processing techniques to segment and cluster the projected structured light line pattern from one single captured image. The coordinates of the clustered lines are extracted to form a low-resolution phase matrix which is then transformed to full-resolution phase map by spline interpolation. The 3D shape of the object is computed from the full-resolution phase map and the 2D camera coordinates. Experimental results show that the proposed method was able to reconstruct the three-dimensional shape of the object robustly from one single image.
Green supply chain: Simulating road traffic congestion
NASA Astrophysics Data System (ADS)
Jalal, Muhammad Zulqarnain Hakim Abd; Nawawi, Mohd Kamal Mohd; Laailatul Hanim Mat Desa, Wan; Khalid, Ruzelan; Khalid Abduljabbar, Waleed; Ramli, Razamin
2017-09-01
With the increasing awareness of the consumers about environmental issues, businesses, households and governments increasingly want use green products and services which lead to green supply chain. This paper discusses a simulation study of a selected road traffic system that will contribute to the air pollution if in the congestion state. Road traffic congestion (RTC) can be caused by a temporary obstruction, a permanent capacity bottleneck in the network itself, and stochastic fluctuation in demand within a particular sector of the network, leading to spillback and queue propagation. A discrete-event simulation model is developed to represent the real traffic light control (TLC) system condition during peak hours. Certain performance measures such as average waiting time and queue length were measured using the simulation model. Existing system uses pre-set cycle time to control the light changes which is fixed time cycle. In this research, we test several other combination of pre-set cycle time with the objective to find the best system. In addition, we plan to use a combination of the pre-set cycle time and a proximity sensor which have the authority to manipulate the cycle time of the lights. The sensors work in such situation when the street seems to have less occupied vehicles, obviously it may not need a normal cycle for green light, and automatically change the cycle to street where vehicle is present.
Space telescope low scattered light camera - A model
NASA Technical Reports Server (NTRS)
Breckinridge, J. B.; Kuper, T. G.; Shack, R. V.
1982-01-01
A design approach for a camera to be used with the space telescope is given. Camera optics relay the system pupil onto an annular Gaussian ring apodizing mask to control scattered light. One and two dimensional models of ripple on the primary mirror were calculated. Scattered light calculations using ripple amplitudes between wavelength/20 wavelength/200 with spatial correlations of the ripple across the primary mirror between 0.2 and 2.0 centimeters indicate that the detection of an object a billion times fainter than a bright source in the field is possible. Detection of a Jovian type planet in orbit about alpha Centauri with a camera on the space telescope may be possible.
On-Orbit Sky Background Measurements with the FOS
NASA Technical Reports Server (NTRS)
Lyons, R. W.; Baity, W. A.; Beaver, E. A.; Cohen, R. D.; Junkkarinen, V. T.; Linsky, J. B.; Bohlin, R. C.
1993-01-01
Observations of the sky background obtained with the Faint Object Spectrograph during 1991-1992 are discussed. Sky light can be an important contributor to the observed count rate in several of the instrument configurations especially when large apertures are used. In general, the sky background is consistent with the pre-launch expectations and showed the expected effects of zodiacal light and diffuse galactic light. In addition to these sources, there is, particularly during the daytime, a highly variable airglow component which includes a number of emission lines. The sky background will have an impact on the reduction and possibly the interpretation of some spectra.
BVRI Photometric Study of the High Mass Ratio, Detached, Pre-contact W UMa Binary GQ Cancri
NASA Astrophysics Data System (ADS)
Samec, R. G.; Olson, A.; Caton, D.; Faulkner, D. R.
2017-12-01
CCD BVRcIc light curves of GQ Cancri were observed in April 2013 using the SARA North 0.9-meter Telescope at Kitt Peak National Observatory in Arizona in remote mode. It is a high-amplitude (V 0.9 magnitude) K0±V type eclipsing binary (T1 5250 K) with a photometrically-determined mass ratio of M2 / M1 = 0.80. Its spectral color type classifies it as a pre-contact W UMa Binary (PCWB). The Wilson-Devinney Mode 2 solutions show that the system has a detached binary configuration with fill-outs of 94% and 98% for the primary and secondary component, respectively. As expected, the light curve is asymmetric due to spot activity. Three times of minimum light were calculated, for two primary eclipses and one secondary eclipse, from our present observations. In total, some 26 times of minimum light covering nearly 20 years of observation were used to determine linear and quadratic ephemerides. It is noted that the light curve solution remained in a detached state for every iteration of the computer runs. The components are very similar with a computed temperature difference of only 4 K, and the flux of the primary component accounts for 53±55% of the system's light in B, V, Rc, and Ic. A 12-degree radius high latitude white spot (faculae) was iterated on the primary component.
Yamamoto, Takatsugu; Ferracane, Jack L; Sakaguchi, Ronald L; Swain, Michael V
2009-04-01
Polymerization contraction of dental composite produces a stress field in the bonded surrounding substrate that may be capable of propagating cracks from pre-existing flaws. The objectives of this study were to assess the extent of crack propagation from flaws in the surrounding ceramic substrate caused by composite contraction stresses, and to propose a method to calculate the contraction stress in the ceramic using indentation fracture. Initial cracks were introduced with a Vickers indenter near a cylindrical hole drilled into a glass-ceramic simulating enamel. Lengths of the radial indentation cracks were measured. Three composites having different contraction stresses were cured within the hole using one- or two-step light-activation methods and the crack lengths were measured. The contraction stress in the ceramic was calculated from the crack length and the fracture toughness of the glass-ceramic. Interfacial gaps between the composite and the ceramic were expressed as the ratio of the gap length to the hole perimeter, as well as the maximum gap width. All groups revealed crack propagation and the formation of contraction gaps. The calculated contraction stresses ranged from 4.2 MPa to 7.0 MPa. There was no correlation between the stress values and the contraction gaps. This method for calculating the stresses produced by composites is a relatively simple technique requiring a conventional hardness tester. The method can investigate two clinical phenomena that may occur during the placement of composite restorations, i.e. simulated enamel cracking near the margins and the formation of contraction gaps.
Four-point functions and the permutation group S4
NASA Astrophysics Data System (ADS)
Eichmann, Gernot; Fischer, Christian S.; Heupel, Walter
2015-09-01
Four-point functions are at the heart of many interesting physical processes. A prime example is the light-by-light scattering amplitude, which plays an important role in the calculation of hadronic contributions to the anomalous magnetic moment of the muon. In the calculation of such quantities one faces the challenge of finding a suitable and well-behaved basis of tensor structures in coordinate and/or momentum space. Provided all (or many) of the external legs represent similar particle content, a powerful tool to construct and organize such bases is the permutation group S4. We introduce an efficient notation for dealing with the irreducible multiplets of S4, and we highlight the merits of this treatment by exemplifying four-point functions with gauge-boson legs such as the four-gluon vertex and the light-by-light scattering amplitude. The multiplet analysis is also useful for isolating the important kinematic regions and the dynamical singularity content of such amplitudes. Our analysis serves as a basis for future efficient calculations of these and similar objects.
Algorithm of resonance orders for the objects
NASA Astrophysics Data System (ADS)
Zhang, YongGang; Zhang, JianXue
2018-03-01
In mechanical engineering, the object resonance phenomena often occur when the external incident wave frequency is close to object of the natural frequency. Object resonance phenomena get the maximum value when the external incident frequency is equal to object the natural frequency. Experiments found that resonance intension of the object is changed, different objects resonance phenomena present different characteristics of ladders. Based on object orders resonance characteristics, the calculation method of object orders resonance is put forward in the paper, and the application for the light and sound waves on the seven order resonance characteristics by people feel, the result error is less than 1%.Visible in this paper, the method has high accuracy and usability. The calculation method reveals that some object resonance occur present order characteristic only four types, namely the first-orders resonance characteristics, third-orders characteristics, five orders characteristic, and seven orders characteristic.
A, Ahamed Basha; C, Mathangi D; R, Shyamala
2016-12-01
Fluorescent light exposure at night alters cellular enzyme activities resulting in health defects. Studies have demonstrated that light emitting diode photobiomodulation enhances cellular enzyme activities. The objectives of this study are to evaluate the effects of fluorescent light induced changes in cellular enzymes and to assess the protective role of pre exposure to 670 nm LED in rat model. Male Wistar albino rats were divided into 10 groups of 6 animals each based on duration of exposure (1, 15, and 30 days) and exposure regimen (cage control, exposure to fluorescent light [1800 lx], LED preexposure followed by fluorescent light exposure and only LED exposure). Na + -K + ATPase, Ca 2+ ATPase, and cytochrome c oxidase of the brain, heart, kidney, liver, and skeletal muscle were assayed. Animals of the fluorescent light exposure group showed a significant reduction in Na + -K + ATPase and Ca 2+ ATPase activities in 1 and 15 days and their increase in animals of 30-day group in most of the regions studied. Cytochrome c oxidase showed increase in their level at all the time points assessed in most of the tissues. LED light preexposure showed a significant enhancement in the degree of increase in the enzyme activities in almost all the tissues and at all the time points assessed. This study demonstrates the protective effect of 670 nm LED pre exposure on cellular enzymes against fluorescent light induced change.
Annoyance caused by light aircraft noise
NASA Technical Reports Server (NTRS)
1981-01-01
The correlation between objective and noise stresses and subjectively perceived disturbance from general aviation aircraft was studied at 6 Swiss airports. Noise levels calculated for these airports are given. Survey results are analyzed.
Effects of Combined Ketamine/Xylazine Anesthesia on Light Induced Retinal Degeneration in Rats
Bolz, Sylvia; Eslava-Schmalbach, Javier; Willmann, Gabriel; Zhour, Ahmad; Zrenner, Eberhart; Fischer, M. Dominik; Gekeler, Florian
2012-01-01
Objectives To explore the effect of ketamine-xylazine anesthesia on light-induced retinal degeneration in rats. Methods Rats were anesthetized with ketamine and xylazine (100 and 5 mg, respectively) for 1 h, followed by a recovery phase of 2 h before exposure to 16,000 lux of environmental illumination for 2 h. Functional assessment by electroretinography (ERG) and morphological assessment by in vivo imaging (optical coherence tomography), histology (hematoxylin/eosin staining, TUNEL assay) and immunohistochemistry (GFAP and rhodopsin staining) were performed at baseline (ERG), 36 h, 7 d and 14 d post-treatment. Non-anesthetized animals treated with light damage served as controls. Results Ketamine-xylazine pre-treatment preserved retinal function and protected against light-induced retinal degeneration. In vivo retinal imaging demonstrated a significant increase of outer nuclear layer (ONL) thickness in the non-anesthetized group at 36 h (p<0.01) and significant reduction one week (p<0.01) after light damage. In contrast, ketamine-xylazine pre-treated animals showed no significant alteration of total retinal or ONL thickness at either time point (p>0.05), indicating a stabilizing and/or protective effect with regard to phototoxicity. Histology confirmed light-induced photoreceptor cell death and Müller cells gliosis in non-anesthetized rats, especially in the superior hemiretina, while ketamine-xylazine treated rats showed reduced photoreceptor cell death (TUNEL staining: p<0.001 after 7 d), thicker ONL and longer IS/OS. Fourteen days after light damage, a reduction of standard flash induced a-wave amplitudes and a-wave slopes (p = 0.01) and significant alterations in parameters of the scotopic sensitivity function (e.g. Vmax of the Naka Rushton fit p = 0.03) were observed in non-treated vs. ketamine-xylazine treated animals. Conclusions Our results suggest that pre-treatment with ketamine-xylazine anesthesia protects retinas against light damage, reducing photoreceptor cell death. These data support the notion that anesthesia with ketamine-xylazine provides neuroprotective effects in light-induced cell damage. PMID:22558200
The intermediate-age pre-cataclysmic variables SDSS J172406+562003 and RE J2013+4002
NASA Astrophysics Data System (ADS)
Shimansky, V. V.; Borisov, N. V.; Nurtdinova, D. N.; Mitrofanova, A. A.; Vlasyuk, V. V.; Spiridonova, O. I.
2012-06-01
We have analyzed the physical status of the pre-cataclysmic variables SDSSJ172406+562003 and RE J2013+4002, which have evolved after their common-envelope stage a time t = 106-107 years. Spectroscopy and photometry of these systems were performed with the 6-m and 1-m telescopes of the Special Astrophysical Observatory. We demonstrate that emission lines in the spectra were formed solely by the reflection of radiation emitted by the white dwarfs on the surfaces of their cool companions, under conditions close to local thermodynamic equilibrium. These effects are also responsible for most of the objects' photometric variability amplitude. However, comparing the light curves of SDSS 172406 from different epochs, we find aperiodic brightness variations, probably due to spottedness of the surface of the secondary. Jointly analyzing the spectra, radial-velocity curves, and light curves of the pre-cataclysmic variables and modeling the reflection effects, we have derived their fundamental parameters. We demonstrate that the secondaries in these systems are consistent with evolutionary models for main-sequence stars and do not have the luminosity excesses characteristic of cool stars in young pre-cataclysmic variables.
Light energy conservation processes in Halobacterium halobium cells
NASA Technical Reports Server (NTRS)
Bogomolni, R. A.
1977-01-01
Proton pumping driven by light or by respiration generates an electrochemical potential difference across the membrane in Halobacterium halobium. The pH changes induced by light or by respiration in cell suspensions are complicated by proton flows associated with the functioning of the cellular energy transducers. A proton-per-ATP ratio of about 3 is calculated from simultaneous measurements of phosphorylation and the proton inflow. This value is compatible with the chemiosmotic coupling hypothesis. The time course of the light-induced changes in membrane potential indicates that light-driven pumping increases a dark pre-existing potential of about 130 mV only by a small amount (20 to 30 mV). The complex kinetic features of the membrane potential changes do not closely follow those of the pH changes, which suggests that flows of ions other than protons are involved. A qualitative model consistent with the available data is presented.
Zoller, Christian Johannes; Hohmann, Ansgar; Foschum, Florian; Geiger, Simeon; Geiger, Martin; Ertl, Thomas Peter; Kienle, Alwin
2018-06-01
A GPU-based Monte Carlo software (MCtet) was developed to calculate the light propagation in arbitrarily shaped objects, like a human tooth, represented by a tetrahedral mesh. A unique feature of MCtet is a concept to realize different kinds of light-sources illuminating the complex-shaped surface of an object, for which no preprocessing step is needed. With this concept, it is also possible to consider photons leaving a turbid media and reentering again in case of a concave object. The correct implementation was shown by comparison with five other Monte Carlo software packages. A hundredfold acceleration compared with central processing units-based programs was found. MCtet can simulate anisotropic light propagation, e.g., by accounting for scattering at cylindrical structures. The important influence of the anisotropic light propagation, caused, e.g., by the tubules in human dentin, is shown for the transmission spectrum through a tooth. It was found that the sensitivity to a change in the oxygen saturation inside the pulp for transmission spectra is much larger if the tubules are considered. Another "light guiding" effect based on a combination of a low scattering and a high refractive index in enamel is described. (2018) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).
Pre-cometary ice composition from hot core chemistry.
Tornow, Carmen; Kührt, Ekkehard; Motschmann, Uwe
2005-10-01
Pre-cometary ice located around star-forming regions contains molecules that are pre-biotic compounds or pre-biotic precursors. Molecular line surveys of hot cores provide information on the composition of the ice since it sublimates near these sites. We have combined a hydrostatic hot core model with a complex network of chemical reactions to calculate the time-dependent abundances of molecules, ions, and radicals. The model considers the interaction between the ice and gas phase. It is applied to the Orion hot core where high-mass star formation occurs, and to the solar-mass binary protostar system IRAS 16293-2422. Our calculations show that at the end of the hot core phase both star-forming sites produce the same prebiotic CN-bearing molecules. However, in the Orion hot core these molecules are formed in larger abundances. A comparison of the calculated values with the abundances derived from the observed line data requires a chemically unprocessed molecular cloud as the initial state of hot core evolution. Thus, it appears that these objects are formed at a much younger cloud stage than previously thought. This implies that the ice phase of the young clouds does not contain CN-bearing molecules in large abundances before the hot core has been formed. The pre-biotic molecules synthesized in hot cores cause a chemical enrichment in the gas phase and in the pre-cometary ice. This enrichment is thought to be an important extraterrestrial aspect of the formation of life on Earth and elsewhere.
Correlation transfer and diffusion of ultrasound-modulated multiply scattered light.
Sakadzić, Sava; Wang, Lihong V
2006-04-28
We develop a temporal correlation transfer equation (CTE) and a temporal correlation diffusion equation (CDE) for ultrasound-modulated multiply scattered light. These equations can be applied to an optically scattering medium with embedded optically scattering and absorbing objects to calculate the power spectrum of light modulated by a nonuniform ultrasound field. We present an analytical solution based on the CDE and Monte Carlo simulation results for light modulated by a cylinder of ultrasound in an optically scattering slab. We further validate with experimental measurements the numerical calculations for an actual ultrasound field. The CTE and CDE are valid for moderate ultrasound pressures and on a length scale comparable with the optical transport mean-free path. These equations should be applicable to a wide spectrum of conditions for ultrasound-modulated optical tomography of soft biological tissues.
Alexandrite-like effect in purple flowers analyzed with newly devised round RGB diagram
Kasajima, Ichiro
2016-01-01
The gemstone alexandrite is known for its feature to change color depending on the spectral quality of the incident light. Thus, the stone looks green when illuminated by white LED light but looks red when illuminated by incandescent light. This effect (alexandrite effect) is caused by a special relationship between the spectral quality of the incident light and the absorbance spectrum of the stone. Here we report an alexandrite-like effect in the petals of torenia and cyclamen flowers. These flowers are purple in sunlight but magenta (reddish) in incandescent light, and violet (bluish purple) in white LED light. The m-n, triangle and round diagrams are devised to calculate the colors of visible light spectra, based on the RGB color-matching function. Using these calculations, the alexandrite-like effect in purple flowers was successfully analyzed in terms of the interaction between the incident light spectrum and the absorbance spectrum of their purple anthocyanin. This analysis allows both logical and intuitive understanding of the colors exhibited by any object showing alexandrite–like properties. PMID:27404088
Infrared system for monitoring movement of objects
Valentine, Kenneth H.; Falter, Diedre D.; Falter, Kelly G.
1991-01-01
A system for monitoring moving objects, such as the flight of honeybees and other insects, using a pulsed laser light source. This system has a self-powered micro-miniaturized transmitting unit powered, in the preferred embodiment, with an array solar cells. This transmitting unit is attached to the object to be monitored. These solar cells provide current to a storage energy capacitor to produce, for example, five volts for the operation of the transmitter. In the simplest embodiment, the voltage on the capacitor operates a pulse generator to provide a pulsed energizing signal to one or more very small laser diodes. The pulsed light is then received at a receiving base station using substantially standard means which converts the light to an electrical signal for processing in a microprocessor to create the information as to the movement of the object. In the case of a unit for monitoring honeybees and other insects, the transmitting unit weighs less than 50 mg, and has a size no larger than 1.times.3.times.5 millimeters. Also, the preferred embodiment provides for the coding of the light to uniquely identify the particular transmitting unit that is being monitored. A "wake-up" circuit is provided in the preferred embodiment whereby there is no transmission until the voltage on the capacitor has exceeded a pre-set threshold. Various other uses of the motion-detection system are described.
Infrared system for monitoring movement of objects
Valentine, K.H.; Falter, D.D.; Falter, K.G.
1991-04-30
A system is described for monitoring moving objects, such as the flight of honeybees and other insects, using a pulsed laser light source. This system has a self-powered micro-miniaturized transmitting unit powered, in the preferred embodiment, with an array of solar cells. This transmitting unit is attached to the object to be monitored. These solar cells provide current to a storage energy capacitor to produce, for example, five volts for the operation of the transmitter. In the simplest embodiment, the voltage on the capacitor operates a pulse generator to provide a pulsed energizing signal to one or more very small laser diodes. The pulsed light is then received at a receiving base station using substantially standard means which converts the light to an electrical signal for processing in a microprocessor to create the information as to the movement of the object. In the case of a unit for monitoring honeybees and other insects, the transmitting unit weighs less than 50 mg, and has a size no larger than 1[times]3[times]5 millimeters. Also, the preferred embodiment provides for the coding of the light to uniquely identify the particular transmitting unit that is being monitored. A wake-up' circuit is provided in the preferred embodiment whereby there is no transmission until the voltage on the capacitor has exceeded a pre-set threshold. Various other uses of the motion-detection system are described. 4 figures.
Competency Based Business Education: Business Math/Related Rules.
ERIC Educational Resources Information Center
Wisconsin Univ., Madison. Wisconsin Vocational Studies Center.
Modules on fractions, decimals, percentages, discounts, interest, the adding machine, and the calculation of a depreciation are included. Each module contains objectives, learning activities, pre-practice exercises, practice exercises, and post-practice exercises. At the beginning of each module, the importance of the module is explained. (MK)
Novel mathematical algorithm for pupillometric data analysis.
Canver, Matthew C; Canver, Adam C; Revere, Karen E; Amado, Defne; Bennett, Jean; Chung, Daniel C
2014-01-01
Pupillometry is used clinically to evaluate retinal and optic nerve function by measuring pupillary response to light stimuli. We have developed a mathematical algorithm to automate and expedite the analysis of non-filtered, non-calculated pupillometric data obtained from mouse pupillary light reflex recordings, obtained from dynamic pupillary diameter recordings following exposure of varying light intensities. The non-filtered, non-calculated pupillometric data is filtered through a low pass finite impulse response (FIR) filter. Thresholding is used to remove data caused by eye blinking, loss of pupil tracking, and/or head movement. Twelve physiologically relevant parameters were extracted from the collected data: (1) baseline diameter, (2) minimum diameter, (3) response amplitude, (4) re-dilation amplitude, (5) percent of baseline diameter, (6) response time, (7) re-dilation time, (8) average constriction velocity, (9) average re-dilation velocity, (10) maximum constriction velocity, (11) maximum re-dilation velocity, and (12) onset latency. No significant differences were noted between parameters derived from algorithm calculated values and manually derived results (p ≥ 0.05). This mathematical algorithm will expedite endpoint data derivation and eliminate human error in the manual calculation of pupillometric parameters from non-filtered, non-calculated pupillometric values. Subsequently, these values can be used as reference metrics for characterizing the natural history of retinal disease. Furthermore, it will be instrumental in the assessment of functional visual recovery in humans and pre-clinical models of retinal degeneration and optic nerve disease following pharmacological or gene-based therapies. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.
Logvinenko, Alexander D.; Funt, Brian; Mirzaei, Hamidreza; Tokunaga, Rumi
2015-01-01
Colour constancy needs to be reconsidered in light of the limits imposed by metamer mismatching. Metamer mismatching refers to the fact that two objects reflecting metameric light under one illumination may reflect non-metameric light under a second; so two objects appearing as having the same colour under one illuminant can appear as having different colours under a second. Yet since Helmholtz, object colour has generally been believed to remain relatively constant. The deviations from colour constancy registered in experiments are usually thought to be small enough that they do not contradict the notion of colour constancy. However, it is important to determine how the deviations from colour constancy relate to the limits metamer mismatching imposes on constancy. Hence, we calculated metamer mismatching’s effect for the 20 Munsell papers and 8 pairs of illuminants employed in the colour constancy study by Logvinenko and Tokunaga and found it to be so extensive that the two notions—metamer mismatching and colour constancy—must be mutually exclusive. In particular, the notion of colour constancy leads to some paradoxical phenomena such as the possibility of 20 objects having the same colour under chromatic light dispersing into a hue circle of colours under neutral light. Thus, colour constancy refers to a phenomenon, which because of metamer mismatching, simply cannot exist. Moreover, it obscures the really important visual phenomenon; namely, the alteration of object colours induced by illumination change. We show that colour is not an independent, intrinsic attribute of an object, but rather an attribute of an object/light pair, and then define a concept of material colour in terms of equivalence classes of such object/light pairs. We suggest that studying the shift in material colour under a change in illuminant will be more fruitful than pursuing colour constancy’s false premise that colour is an intrinsic attribute of an object. PMID:26356217
NASA Astrophysics Data System (ADS)
Zhu, Wei; Chen, Qianghua; Wang, Yanghong; Luo, Huifu; Wu, Huan; Ma, Binwu
2018-06-01
In the laser self-mixing interference vibration measurement system, the self mixing interference signal is usually weak so that it can be hardly distinguished from the environmental noise. In order to solve this problem, we present a self-mixing interference optical path with a pre-feedback mirror, a pre-feedback mirror is added between the object and the collimator lens, corresponding feedback light enters into the inner cavity of the laser and the interference by the pre-feedback mirror occurs. The pre-feedback system is established after that. The self-mixing interference theoretical model with a pre-feedback based on the F-P model is derived. The theoretical analysis shows that the amplitude of the intensity of the interference signal can be improved by 2-4 times. The influence factors of system are also discussed. The experiment results show that the amplitude of the signal is greatly improved, which agrees with the theoretical analysis.
Improved resolution in practical light microscopy by means of a glass-fiber 2 π-tilting device
NASA Astrophysics Data System (ADS)
Bradl, Joachim; Rinke, Bernd; Schneider, Bernhard; Hausmann, Michael; Cremer, Christoph G.
1996-01-01
The spatial resolution of a conventional light microscope or a confocal laser scanning microscope can be determined by calculating the point spread function for the objective used. Normally, ideal conditions are assumed for these calculations. Such conditions, however, are often not fulfilled in biological applications especially in those cases where biochemical requirements (e.g. buffer conditions) influence the specimen preparation on the microscope slide (i.e. 'practical' light microscopy). It has been shown that the problem of a reduced z- resolution in 3D-microscopy (optical sectioning) can be overcome by a capillary in a 2(pi) - tilting device that allows object rotation into an optimal perspective. The application of the glass capillary instead of a standard slide has an additional influence on the imaging properties of the microscope. Therefore, another 2(pi) -tilting device was developed, using a glass fiber for object fixation and rotation. Such a fiber could be covered by standard cover glasses. To estimate the resolution of this setup, point spread functions were measured under different conditions using fluorescent microspheres of subwavelength dimensions. Results obtained from standard slide setups were compared to the glass fiber setup. These results showed that in practice rotation leads to an overall 3D-resolution improvement.
Laser scanning system for object monitoring
McIntyre, Timothy James [Knoxville, TN; Maxey, Lonnie Curtis [Powell, TN; Chiaro, Jr; John, Peter [Clinton, TN
2008-04-22
A laser scanner is located in a fixed position to have line-of-sight access to key features of monitored objects. The scanner rapidly scans pre-programmed points corresponding to the positions of retroreflecting targets affixed to the key features of the objects. The scanner is capable of making highly detailed scans of any portion of the field of view, permitting the exact location and identity of targets to be confirmed. The security of an object is verified by determining that the cooperative target is still present and that its position has not changed. The retroreflecting targets also modulate the reflected light for purposes of returning additional information back to the location of the scanner.
New methods for deriving cometary secular light curves: C/1995 O1 (Hale-Bopp) revisited
NASA Astrophysics Data System (ADS)
Womack, Maria; Lastra, Nathan; Harrington, Olga; Curtis, Anthony; Wierzchos, Kacper; Ruffini, Nicholas; Charles, Mentzer; Rabson, David; Cox, Timothy; Rivera, Isabel; Micciche, Anthony
2017-10-01
We present an algorithm for reducing scatter and increasing precision in a comet light curve. As a demonstration, we processed apparent magnitudes of comet Hale-Bopp from 16 highly experienced observers (archived with the International Comet Quarterly), correcting for distance from Earth and phase angle. Different observers tend to agree on the difference in magnitudes of an object at different distances, but the magnitude reported by observer is shifted relative to that of another for an object at a fixed distance. We estimated the shifts using a self-consistent statistical approach, leading to a sharper light curve and improving the precision of the measured slopes. The final secular lightcurve for comet Hale-Bopp ranges from -7 au (pre-perihelion) to +8 au (post-perihelion) and is the best secular light curve produced to date for this “great” comet. We discuss Hale-Bopp’s lightcurve evolution and possibly related physical implications, and potential usefulness of this light curve for comparisons with other future bright comets. We also assess the appropriateness of using secular lightcurves to characterize dust production rates in Hale-Bopp and other dust-rich comets. M.W. acknowledges support from NSF grant AST-1615917.
A phase response curve to single bright light pulses in human subjects
NASA Technical Reports Server (NTRS)
Khalsa, Sat Bir S.; Jewett, Megan E.; Cajochen, Christian; Czeisler, Charles A.
2003-01-01
The circadian pacemaker is differentially sensitive to the resetting effects of retinal light exposure, depending upon the circadian phase at which the light exposure occurs. Previously reported human phase response curves (PRCs) to single bright light exposures have employed small sample sizes, and were often based on relatively imprecise estimates of circadian phase and phase resetting. In the present study, 21 healthy, entrained subjects underwent pre- and post-stimulus constant routines (CRs) in dim light (approximately 2-7 lx) with maintained wakefulness in a semi-recumbent posture. The 6.7 h bright light exposure stimulus consisted of alternating 6 min fixed gaze (approximately 10 000 lx) and free gaze (approximately 5000-9000 lx) exposures. Light exposures were scheduled across the circadian cycle in different subjects so as to derive a PRC. Plasma melatonin was used to determine the phase of the onset, offset, and midpoint of the melatonin profiles during the CRs. Phase shifts were calculated as the difference in phase between the pre- and post-stimulus CRs. The resultant PRC of the midpoint of the melatonin rhythm revealed a characteristic type 1 PRC with a significant peak-to-trough amplitude of 5.02 h. Phase delays occurred when the light stimulus was centred prior to the critical phase at the core body temperature minimum, phase advances occurred when the light stimulus was centred after the critical phase, and no phase shift occurred at the critical phase. During the subjective day, no prolonged 'dead zone' of photic insensitivity was apparent. Phase shifts derived using the melatonin onsets showed larger magnitudes than those derived from the melatonin offsets. These data provide a comprehensive characterization of the human PRC under highly controlled laboratory conditions.
Kakudo, Natsuko; Kushida, Satoshi; Suzuki, Kenji; Kusumoto, Kenji
2013-12-01
Chemical peeling is becoming increasingly popular for skin rejuvenation in dermatological cosmetic medicine. However, the improvements seen with chemical peeling are often very minor, and it is difficult to conduct a quantitative assessment of pre- and post-treatment appearance. We report the pre- and postpeeling effects for facial pigment deposition using a novel computer analysis method for digital-camera-captured images. Glycolic acid chemical peeling was performed a total of 5 times at 2-week intervals in 23 healthy women. We conducted a computer image analysis by utilizing Robo Skin Analyzer CS 50 and Clinical Suite 2.1 and then reviewed each parameter for the area of facial pigment deposition pre- and post-treatment. Parameters were pigmentation size and four pigmentation categories: little pigmentation and three levels of marked pigmentation (Lv1, 2, and 3) based on detection threshold. Each parameter was measured, and the total area of facial pigmentation was calculated. The total area of little pigmentation and marked pigmentation (Lv1) was significantly reduced. On the other hand, a significant difference was not observed for the total area of marked pigmentation Lv2 and Lv3. This suggests that glycolic acid chemical peeling has an effect on small facial pigment disposition or has an effect on light pigment deposition. As the Robo Skin Analyzer is useful for objectively quantifying and analyzing minor changes in facial skin, it is considered to be an effective tool for accumulating treatment evidence in the cosmetic and esthetic skin field. © 2013 Wiley Periodicals, Inc.
Sequential, progressive, equal-power, reflective beam-splitter arrays
NASA Astrophysics Data System (ADS)
Manhart, Paul K.
2017-11-01
The equations to calculate equal-power reflectivity of a sequential series of beam splitters is presented. Non-sequential optical design examples are offered for uniform illumination using diode lasers. Objects created using Boolean operators and Swept Surfaces can create objects capable of reflecting light into predefined elevation and azimuth angles. Analysis of the illumination patterns for the array are also presented.
Nucleosynthesis during a Thermonuclear Supernova Explosion
NASA Astrophysics Data System (ADS)
Panov, I. V.; Glazyrin, S. I.; Röpke, F. K.; Blinnikov, S. I.
2018-05-01
Supernovae are such bright objects that they can be observed even at high redshifts. Some types of such events, for example, type Ia (thermonuclear), have peculiarities of the light curve, which allows them to be used for cosmological applications. The light curve is determined by the details of the explosion dynamics and nucleosynthesis: in particular, it depends on the amount of iron-peak elements produced during the explosion. We discuss the burning processes in such objects and the peculiarities of turbulence simulations in them, which is needed for a proper hydrodynamic description of the explosion process. A direct nucleosynthesis calculation is performed for the temperature and density profiles derived in the available 3D hydrodynamic explosion simulations. We show that in the supernova progenitor model considered the calculated abundances of elements from carbon to iron-peak elements are in good agreement both with the observations and with the calculations of other authors. At the same time, no r-elements are produced even at the maximum neutron excess for this model ( Y e 0.47) due to the slow evolution of the density and temperature.
NASA Astrophysics Data System (ADS)
Larionova, Kira; Stetsky, Sergey
2018-03-01
The main rationale and objective of the submitted research work is to create a quality lighting environment in the premises of deepened buildings and below-ground structures under screen effect of high-rise construction (high-rise buildings). It is noted, that in modern megapolises, a deficiency of vacant urban territories leads to the increased density of urban development with increased amount of high-rise construction and tendency to increase efficiency in the use of underground space. The natural lighting of premises in underground buildings and structures is the most efficient way, but it can be implemented only under use of roof lighting system in the form of roof monitors or skylights. In this case the levels of indoor natural lighting will be affected with serious screening effect of high-rise buildings in surrounding development. Such an situation is not regulated, or even considered by the contemporary building Codes and Regulations on natural lighting of interiors. The authors offered a new formula for a daylight factor calculation with roof lighting system in the described cases. The results of theoretical calculations and experimental studies showed very similar values. This proved the truth of the offered formula and elaborated method of calculation on the basis of an offered hypothesis. It prooves, that it is possible to use some factor and guide points in the daylight factors design under system of side natural lighting in the same design for a system of roof lighting.
Application of space periodic variation of light polarization in imaging polarimetry
DOE Office of Scientific and Technical Information (OSTI.GOV)
Drobczynski, Slawomir; Kasprzak, Henryk
The application of space periodic variation of light polarization for measurement and calculation of the distribution of the phase retardation between two eigenwaves propagating inside a linearly birefringent media and the distribution of the azimuth angle of the first eigenvector is described. The measuring method proposed does not require any mechanical movements or rotations of any optical elements. Application of a liquid crystal (LC) modulator instead of a quarter-wave plate gives an opportunity to introduce the required phase shift. The space periodic modulation of the polarization of light is achieved by the use of a Wollaston prism placed inside themore » path of the light beam. Then a fast Fourier transform is used for further calculations. The number of measurements of the light intensity at the output of the system is minimized to two. These assumptions make the proposed method very fast, which is especially important in measurements of the objects with optical anisotropy that is changing in time.« less
MM Herculis - An eclipsing binary of the RS CVn
NASA Technical Reports Server (NTRS)
Sowell, J. R.; Hall, D. S.; Henry, G. W.; Burke, E. W., Jr.; Milone, E. F.
1983-01-01
V, B and U differential photoelectric photometry has been obtained for the RS Canum Venaticorum-class eclipsing binary star MM Her, with the light outside the eclipse being Fourier-analyzed to study wave migration and amplitude. These, together with the mean light level of the system, have been monitored from 1976 through 1980. Observations within the eclipse have revealed eclipses to be partial, rather than total as previously thought. The geometric elements of the presently rectified light curve are forced on the pre-1980 light curves and found to be compatible. With these elements, and previously obtained double line radial velocity curves, new absolute dimensions of 1.18 solar masses and 1.58 solar radii are calculated for the hotter star and 1.27 solar masses and 2.83 solar radii for the cooler star. The plotting of color indices on the color-color curve indicates G2V and K2IV spectral types.
Numerical Simulation of Partially-Coherent Broadband Optical Imaging Using the FDTD Method
Çapoğlu, İlker R.; White, Craig A.; Rogers, Jeremy D.; Subramanian, Hariharan; Taflove, Allen; Backman, Vadim
2012-01-01
Rigorous numerical modeling of optical systems has attracted interest in diverse research areas ranging from biophotonics to photolithography. We report the full-vector electromagnetic numerical simulation of a broadband optical imaging system with partially-coherent and unpolarized illumination. The scattering of light from the sample is calculated using the finite-difference time-domain (FDTD) numerical method. Geometrical optics principles are applied to the scattered light to obtain the intensity distribution at the image plane. Multilayered object spaces are also supported by our algorithm. For the first time, numerical FDTD calculations are directly compared to and shown to agree well with broadband experimental microscopy results. PMID:21540939
NASA Astrophysics Data System (ADS)
Niwase, Hiroaki; Takada, Naoki; Araki, Hiromitsu; Maeda, Yuki; Fujiwara, Masato; Nakayama, Hirotaka; Kakue, Takashi; Shimobaba, Tomoyoshi; Ito, Tomoyoshi
2016-09-01
Parallel calculations of large-pixel-count computer-generated holograms (CGHs) are suitable for multiple-graphics processing unit (multi-GPU) cluster systems. However, it is not easy for a multi-GPU cluster system to accomplish fast CGH calculations when CGH transfers between PCs are required. In these cases, the CGH transfer between the PCs becomes a bottleneck. Usually, this problem occurs only in multi-GPU cluster systems with a single spatial light modulator. To overcome this problem, we propose a simple method using the InfiniBand network. The computational speed of the proposed method using 13 GPUs (NVIDIA GeForce GTX TITAN X) was more than 3000 times faster than that of a CPU (Intel Core i7 4770) when the number of three-dimensional (3-D) object points exceeded 20,480. In practice, we achieved ˜40 tera floating point operations per second (TFLOPS) when the number of 3-D object points exceeded 40,960. Our proposed method was able to reconstruct a real-time movie of a 3-D object comprising 95,949 points.
Structured light optical microscopy for three-dimensional reconstruction of technical surfaces
NASA Astrophysics Data System (ADS)
Kettel, Johannes; Reinecke, Holger; Müller, Claas
2016-04-01
In microsystems technology quality control of micro structured surfaces with different surface properties is playing an ever more important role. The process of quality control incorporates three-dimensional (3D) reconstruction of specularand diffusive reflecting technical surfaces. Due to the demand on high measurement accuracy and data acquisition rates, structured light optical microscopy has become a valuable solution to solve this problem providing high vertical and lateral resolution. However, 3D reconstruction of specular reflecting technical surfaces still remains a challenge to optical measurement principles. In this paper we present a measurement principle based on structured light optical microscopy which enables 3D reconstruction of specular- and diffusive reflecting technical surfaces. It is realized using two light paths of a stereo microscope equipped with different magnification levels. The right optical path of the stereo microscope is used to project structured light onto the object surface. The left optical path is used to capture the structured illuminated object surface with a camera. Structured light patterns are generated by a Digital Light Processing (DLP) device in combination with a high power Light Emitting Diode (LED). Structured light patterns are realized as a matrix of discrete light spots to illuminate defined areas on the object surface. The introduced measurement principle is based on multiple and parallel processed point measurements. Analysis of the measured Point Spread Function (PSF) by pattern recognition and model fitting algorithms enables the precise calculation of 3D coordinates. Using exemplary technical surfaces we demonstrate the successful application of our measurement principle.
ERIC Educational Resources Information Center
Ghoneim, Nahed Mohammed Mahmoud; Elghotmy, Heba Elsayed Abdelsalam
2016-01-01
Knowledge Investment is a new and unique concept. Converting the output of scientific research into reality requires a promising start-up. Knowledge economy should be given the priority it deserves and be considered one of the strategic objectives of the development plans in Egypt. With English increasingly being positioned as the pre-eminent…
USDA-ARS?s Scientific Manuscript database
Recent advances in remote sensing and land data assimilation purport to improve the quality of antecedent soil moisture information available for operational hydrologic forecasting. We objectively validate this claim by calculating the strength of the relationship between storm-scale runoff ratio (i...
Pre-main sequence sun: a dynamic approach
DOE Office of Scientific and Technical Information (OSTI.GOV)
Newman, M.J.; Winkler, K.H.A.
1979-01-01
The classical pre-main sequence evolutionary behavior found by Hayashi and his coworkers for the Sun depends crucially on the choice of initial conditions. The Hayashi picture results from beginning the calculation with an already centrally condensed, highly Jeans unstable object not terribly far removed from the stellar state initially. The present calculation follows the work of Larson in investigating the hydrodynamic collapse and self-gravitational accretion of an initially uniform, just Jeans unstable interstellar gas-dust cloud. The resulting picture for the early history of the Sun is quite different from that found by Hayashi. A rather small (R approx. = 2more » R/sub sun/), low-luminosity (L greater than or equal to L/sub sun/) protostellar core develops. A fully convective stellar core, characteristic of Hayashi's work, is not found during the accretion process, and can only develop, if at all, in the subsequent pre-main sequence Kelvin-Helmholtz contraction of the core. 3 figures, 1 table.« less
Speiser, Daniel I; Pankey, M Sabrina; Zaharoff, Alexander K; Battelle, Barbara A; Bracken-Grissom, Heather D; Breinholt, Jesse W; Bybee, Seth M; Cronin, Thomas W; Garm, Anders; Lindgren, Annie R; Patel, Nipam H; Porter, Megan L; Protas, Meredith E; Rivera, Ajna S; Serb, Jeanne M; Zigler, Kirk S; Crandall, Keith A; Oakley, Todd H
2014-11-19
Tools for high throughput sequencing and de novo assembly make the analysis of transcriptomes (i.e. the suite of genes expressed in a tissue) feasible for almost any organism. Yet a challenge for biologists is that it can be difficult to assign identities to gene sequences, especially from non-model organisms. Phylogenetic analyses are one useful method for assigning identities to these sequences, but such methods tend to be time-consuming because of the need to re-calculate trees for every gene of interest and each time a new data set is analyzed. In response, we employed existing tools for phylogenetic analysis to produce a computationally efficient, tree-based approach for annotating transcriptomes or new genomes that we term Phylogenetically-Informed Annotation (PIA), which places uncharacterized genes into pre-calculated phylogenies of gene families. We generated maximum likelihood trees for 109 genes from a Light Interaction Toolkit (LIT), a collection of genes that underlie the function or development of light-interacting structures in metazoans. To do so, we searched protein sequences predicted from 29 fully-sequenced genomes and built trees using tools for phylogenetic analysis in the Osiris package of Galaxy (an open-source workflow management system). Next, to rapidly annotate transcriptomes from organisms that lack sequenced genomes, we repurposed a maximum likelihood-based Evolutionary Placement Algorithm (implemented in RAxML) to place sequences of potential LIT genes on to our pre-calculated gene trees. Finally, we implemented PIA in Galaxy and used it to search for LIT genes in 28 newly-sequenced transcriptomes from the light-interacting tissues of a range of cephalopod mollusks, arthropods, and cubozoan cnidarians. Our new trees for LIT genes are available on the Bitbucket public repository ( http://bitbucket.org/osiris_phylogenetics/pia/ ) and we demonstrate PIA on a publicly-accessible web server ( http://galaxy-dev.cnsi.ucsb.edu/pia/ ). Our new trees for LIT genes will be a valuable resource for researchers studying the evolution of eyes or other light-interacting structures. We also introduce PIA, a high throughput method for using phylogenetic relationships to identify LIT genes in transcriptomes from non-model organisms. With simple modifications, our methods may be used to search for different sets of genes or to annotate data sets from taxa outside of Metazoa.
From protostellar to pre-main-sequence evolution
NASA Astrophysics Data System (ADS)
D'Antona, F.
I summarize the status of pre-main-sequence evolutionary tracks starting from the first steps dating back to the concept of Hayashi track. Understanding of the dynamical protostellar phase in the vision of Palla & Stahler, who introduced the concept of the deuterium burning thermostat and of stellar birthline, provided for a long time a link between the dynamical and hydrostatic evolution. Disk accretion however changed considerably the view, but re-introducing some ambiguities which must still be solved. The limitations and uncertainties in the mass and age determination from models for young stellar objects are summarized, but the burning of light elements is still a powerful observational signature.
Cross correlation anomaly detection system
NASA Technical Reports Server (NTRS)
Micka, E. Z. (Inventor)
1975-01-01
This invention provides a method for automatically inspecting the surface of an object, such as an integrated circuit chip, whereby the data obtained by the light reflected from the surface, caused by a scanning light beam, is automatically compared with data representing acceptable values for each unique surface. A signal output provided indicated of acceptance or rejection of the chip. Acceptance is based on predetermined statistical confidence intervals calculated from known good regions of the object being tested, or their representative values. The method can utilize a known good chip, a photographic mask from which the I.C. was fabricated, or a computer stored replica of each pattern being tested.
Fast object reconstruction in block-based compressive low-light-level imaging
NASA Astrophysics Data System (ADS)
Ke, Jun; Sui, Dong; Wei, Ping
2014-11-01
In this paper we propose a simply yet effective and efficient method for long-term object tracking. Different from traditional visual tracking method which mainly depends on frame-to-frame correspondence, we combine high-level semantic information with low-level correspondences. Our framework is formulated in a confidence selection framework, which allows our system to recover from drift and partly deal with occlusion problem. To summarize, our algorithm can be roughly decomposed in a initialization stage and a tracking stage. In the initialization stage, an offline classifier is trained to get the object appearance information in category level. When the video stream is coming, the pre-trained offline classifier is used for detecting the potential target and initializing the tracking stage. In the tracking stage, it consists of three parts which are online tracking part, offline tracking part and confidence judgment part. Online tracking part captures the specific target appearance information while detection part localizes the object based on the pre-trained offline classifier. Since there is no data dependence between online tracking and offline detection, these two parts are running in parallel to significantly improve the processing speed. A confidence selection mechanism is proposed to optimize the object location. Besides, we also propose a simple mechanism to judge the absence of the object. If the target is lost, the pre-trained offline classifier is utilized to re-initialize the whole algorithm as long as the target is re-located. During experiment, we evaluate our method on several challenging video sequences and demonstrate competitive results.
Simulating the nasal cycle with computational fluid dynamics
Patel, Ruchin G.; Garcia, Guilherme J. M.; Frank-Ito, Dennis O.; Kimbell, Julia S.; Rhee, John S.
2015-01-01
Objectives (1) Develop a method to account for the confounding effect of the nasal cycle when comparing pre- and post-surgery objective measures of nasal patency. (2) Illustrate this method by reporting objective measures derived from computational fluid dynamics (CFD) models spanning the full range of mucosal engorgement associated with the nasal cycle in two subjects. Study Design Retrospective Setting Academic tertiary medical center. Subjects and Methods A cohort of 24 nasal airway obstruction patients was reviewed to select the two patients with the greatest reciprocal change in mucosal engorgement between pre- and post-surgery computed tomography (CT) scans. Three-dimensional anatomic models were created based on the pre- and post-operative CT scans. Nasal cycling models were also created by gradually changing the thickness of the inferior turbinate, middle turbinate, and septal swell body. CFD was used to simulate airflow and to calculate nasal resistance and average heat flux. Results Before accounting for the nasal cycle, Patient A appeared to have a paradoxical worsening nasal obstruction in the right cavity postoperatively. After accounting for the nasal cycle, Patient A had small improvements in objective measures postoperatively. The magnitude of the surgical effect also differed in Patient B after accounting for the nasal cycle. Conclusion By simulating the nasal cycle and comparing models in similar congestive states, surgical changes in nasal patency can be distinguished from physiological changes associated with the nasal cycle. This ability can lead to more precise comparisons of pre and post-surgery objective measures and potentially more accurate virtual surgery planning. PMID:25450411
DOE Office of Scientific and Technical Information (OSTI.GOV)
Korovin, Yu. A.; Maksimushkina, A. V., E-mail: AVMaksimushkina@mephi.ru; Frolova, T. A.
2016-12-15
The cross sections of nuclear reactions involving emission of clusters of light nuclei in proton collisions with a heavy-metal target are computed for incident-proton energies between 30 MeV and 2.6 GeV. The calculation relies on the ALICE/ASH and CASCADE/INPE computer codes. The parameters determining the pre-equilibrium cluster emission are varied in the computation.
Enhancement of polarizabilities of cylinders with cylinder-slab resonances
Xiao, Meng; Huang, Xueqin; Liu, H.; Chan, C. T.
2015-01-01
If an object is very small in size compared with the wavelength of light, it does not scatter light efficiently. It is hence difficult to detect a very small object with light. We show using analytic theory as well as full wave numerical calculation that the effective polarizability of a small cylinder can be greatly enhanced by coupling it with a superlens type metamaterial slab. This kind of enhancement is not due to the individual resonance effect of the metamaterial slab, nor due to that of the object, but is caused by a collective resonant mode between the cylinder and the slab. We show that this type of particle-slab resonance which makes a small two-dimensional object much “brighter” is actually closely related to the reverse effect known in the literature as “cloaking by anomalous resonance” which can make a small cylinder undetectable. We also show that the enhancement of polarizability can lead to strongly enhanced electromagnetic forces that can be attractive or repulsive, depending on the material properties of the cylinder. PMID:25641391
When holography meets coherent diffraction imaging.
Latychevskaia, Tatiana; Longchamp, Jean-Nicolas; Fink, Hans-Werner
2012-12-17
The phase problem is inherent to crystallographic, astronomical and optical imaging where only the intensity of the scattered signal is detected and the phase information is lost and must somehow be recovered to reconstruct the object's structure. Modern imaging techniques at the molecular scale rely on utilizing novel coherent light sources like X-ray free electron lasers for the ultimate goal of visualizing such objects as individual biomolecules rather than crystals. Here, unlike in the case of crystals where structures can be solved by model building and phase refinement, the phase distribution of the wave scattered by an individual molecule must directly be recovered. There are two well-known solutions to the phase problem: holography and coherent diffraction imaging (CDI). Both techniques have their pros and cons. In holography, the reconstruction of the scattered complex-valued object wave is directly provided by a well-defined reference wave that must cover the entire detector area which often is an experimental challenge. CDI provides the highest possible, only wavelength limited, resolution, but the phase recovery is an iterative process which requires some pre-defined information about the object and whose outcome is not always uniquely-defined. Moreover, the diffraction patterns must be recorded under oversampling conditions, a pre-requisite to be able to solve the phase problem. Here, we report how holography and CDI can be merged into one superior technique: holographic coherent diffraction imaging (HCDI). An inline hologram can be recorded by employing a modified CDI experimental scheme. We demonstrate that the amplitude of the Fourier transform of an inline hologram is related to the complex-valued visibility, thus providing information on both, the amplitude and the phase of the scattered wave in the plane of the diffraction pattern. With the phase information available, the condition of oversampling the diffraction patterns can be relaxed, and the phase problem can be solved in a fast and unambiguous manner. We demonstrate the reconstruction of various diffraction patterns of objects recorded with visible light as well as with low-energy electrons. Although we have demonstrated our HCDI method using laser light and low-energy electrons, it can also be applied to any other coherent radiation such as X-rays or high-energy electrons.
Using Light Curves to Characterize Size and Shape of Pseudo-Debris
NASA Technical Reports Server (NTRS)
Rodriquez, Heather M.; Abercromby, Kira J.; Jarvis, Kandy S.; Barker, Edwin
2006-01-01
Photometric measurements were collected for a new study aimed at estimating orbital debris sizes based on object brightness. To obtain a size from optical measurements the current practice is to assume an albedo and use a normalized magnitude to calculate optical size. However, assuming a single albedo value may not be valid for all objects or orbit types; material type and orientation can mask an object s true optical cross section. This experiment used a CCD camera to record data, a 300 W Xenon, Ozone Free collimated light source to simulate solar illumination, and a robotic arm with five degrees of freedom to move the piece of simulated debris through various orientations. The pseudo-debris pieces used in this experiment originate from the European Space Operations Centre s ESOC2 ground test explosion of a mock satellite. A uniformly illuminated white ping-pong ball was used as a zero-magnitude reference. Each debris piece was then moved through specific orientations and rotations to generate a light curve. This paper discusses the results of five different object-based light curves as measured through an x-rotation. Intensity measurements, from which each light curve was generated, were recorded in five degree increments from zero to 180 degrees. Comparing light curves of different shaped and sized pieces against their characteristic length establishes the start of a database from which an optical size estimation model will be derived in the future.
T1 mapping and survival in systemic light-chain amyloidosis
Banypersad, Sanjay M.; Fontana, Marianna; Maestrini, Viviana; Sado, Daniel M.; Captur, Gabriella; Petrie, Aviva; Piechnik, Stefan K.; Whelan, Carol J.; Herrey, Anna S.; Gillmore, Julian D.; Lachmann, Helen J.; Wechalekar, Ashutosh D.; Hawkins, Philip N.; Moon, James C.
2015-01-01
Aims To assess the prognostic value of myocardial pre-contrast T1 and extracellular volume (ECV) in systemic amyloid light-chain (AL) amyloidosis using cardiovascular magnetic resonance (CMR) T1 mapping. Methods and results One hundred patients underwent CMR and T1 mapping pre- and post-contrast. Myocardial ECV was calculated at contrast equilibrium (ECVi) and 15 min post-bolus (ECVb). Fifty-four healthy volunteers served as controls. Patients were followed up for a median duration of 23 months and survival analyses were performed. Mean ECVi was raised in amyloid (0.44 ± 0.12) as was ECVb (mean 0.44 ± 0.12) compared with healthy volunteers (0.25 ± 0.02), P < 0.001. Native pre-contrast T1 was raised in amyloid (mean 1080 ± 87 ms vs. 954 ± 34 ms, P < 0.001). All three correlated with pre-test probability of cardiac involvement, cardiac biomarkers, and systolic and diastolic dysfunction. During follow-up, 25 deaths occurred. An ECVi of >0.45 carried a hazard ratio (HR) for death of 3.84 [95% confidence interval (CI): 1.53–9.61], P = 0.004 and pre-contrast T1 of >1044 ms = HR 5.39 (95% CI: 1.24–23.4), P = 0.02. Extracellular volume after primed infusion and ECVb performed similarly. Isolated post-contrast T1 was non-predictive. In Cox regression models, ECVi was independently predictive of mortality (HR = 4.41, 95% CI: 1.35–14.4) after adjusting for E:E′, ejection fraction, diastolic dysfunction grade, and NT-proBNP. Conclusion Myocardial ECV (bolus or infusion technique) and pre-contrast T1 are biomarkers for cardiac AL amyloid and they predict mortality in systemic amyloidosis. PMID:25411195
Light sensors for objective light measurement in ambulatory polysomnography.
Schembri, Rachel; Spong, Jo; Peters, Allison; Rochford, Peter; Wilksch, Philip; O'Donoghue, Fergal J; Greenwood, Kenneth M; Barnes, Maree; Kennedy, Gerard A; Berlowitz, David J
2017-01-01
Ambulatory polysomnography (PSG) does not commonly include an objective measure of light to determine the time of lights off (Loff), and thus cannot be used to calculate important indices such as sleep onset latency and sleep efficiency. This study examined the technical specifications and appropriateness of a prototype light sensor (LS) for use in ambulatory Compumedics Somte PSG.Two studies were conducted. The first examined the light measurement characteristics of the LS when used with a portable PSG device, specifically recording trace range, linearity, sensitivity, and stability. This involved the LS being exposed to varying incandescent and fluorescent light levels in a light controlled room. Secondly, the LS was trialled in 24 home and 12 hospital ambulatory PSGs to investigate whether light levels in home and hospital settings were within the recording range of the LS, and to quantify the typical light intensity reduction at the time of Loff. A preliminary exploration of clinical utility was also conducted. Linearity between LS voltage and lux was demonstrated, and the LS trace was stable over 14 hours of recording. The observed maximum voltage output of the LS/PSG device was 250 mV, corresponding to a maximum recording range of 350 lux and 523 lux for incandescent and fluorescent light respectively. At the time of Loff, light levels were within the recording range of the LS, and on average dropped by 72 lux (9-245) in the home and 76 lux (4-348) in the hospital setting. Results suggest that clinical utility was greatest in hospital settings where patients are less mobile. The LS was a simple and effective objective marker of light level in portable PSG, which can be used to identify Loff in ambulatory PSG. This allows measurement of additional sleep indices and support with clinical decisions.
The design of a small flow optical sensor of particle counter
NASA Astrophysics Data System (ADS)
Zhan, Yongbo; zhang, Jianwei; Zeng, Jianxiong; Li, Bin; Chen, Lu
2018-01-01
Based on the principle of Mie scattering, we design a small flow optical sensor of particle counter. Firstly, laser illumination system was simulated and designed by ZEMAX optical design software, and the uniform light intensity of photosensitive area was obtained. The gas circuit structure was also designed according to the related theory of fluid mechanics. Then, the method of combining with MIST scattering calculation software and geometric modeling was firstly used to design spherical reflection system, on the basis of the formula of object-image distance. Finally, the test was conducted after the optical sensor placed in self-designed pre-amplification and high-speed processing circuit. The test results show that the counting efficiency of 0.3 μm gear is above 70%, 0.5 μm gear and 1.0 μm gear are both reached more than 90%, and the dispersion coefficient of each gear is very nearly the same, compared with the standard machine of Kanomax 3886 under the particle spraying flow of 2.5SCFH, 3.0SCFH, 3.5SCFH.
Research on pre-scientific concept of light in children's cognitive activity
NASA Astrophysics Data System (ADS)
Lan, Zhigao; Yu, Yang; Yan, Dan; Yang, Shulin
2017-08-01
Based on the theory of Ausubel's meaningful learning and cognitive characteristic of childens pre-scientific concept, two students of Huang Gang Middle School have been interviewed continuously about cognition of interaction between light and matter. Comprehension degree of childens pre-scientific concept about interaction between light and matter has been deeply understood, formation of strategy of childens pre-scientific concept has been discussed. Several influence factors related to formation of childens pre-scientific concept have been analyzed, such as sex, family environment, and learning experience of kindergarten and primary school.
Being Careful with PASCO's Kinetic Friction Experiment: Uncovering Pre-Sliding Displacement?
ERIC Educational Resources Information Center
Lawlor, T. M.
2008-01-01
The widely used PASCO laboratory equipment is an excellent way to introduce students to many topics in physics. In one case, PASCO's equipment may be too good! Various experiments exist for calculating the kinetic coefficient of friction by measuring the acceleration of a sliding object under some constant force. With ever more accurate equipment,…
Stereoscopic augmented reality with pseudo-realistic global illumination effects
NASA Astrophysics Data System (ADS)
de Sorbier, Francois; Saito, Hideo
2014-03-01
Recently, augmented reality has become very popular and has appeared in our daily life with gaming, guiding systems or mobile phone applications. However, inserting object in such a way their appearance seems natural is still an issue, especially in an unknown environment. This paper presents a framework that demonstrates the capabilities of Kinect for convincing augmented reality in an unknown environment. Rather than pre-computing a reconstruction of the scene like proposed by most of the previous method, we propose a dynamic capture of the scene that allows adapting to live changes of the environment. Our approach, based on the update of an environment map, can also detect the position of the light sources. Combining information from the environment map, the light sources and the camera tracking, we can display virtual objects using stereoscopic devices with global illumination effects such as diffuse and mirror reflections, refractions and shadows in real time.
NASA Astrophysics Data System (ADS)
Doulgerakis, Matthaios; Eggebrecht, Adam; Wojtkiewicz, Stanislaw; Culver, Joseph; Dehghani, Hamid
2017-12-01
Parameter recovery in diffuse optical tomography is a computationally expensive algorithm, especially when used for large and complex volumes, as in the case of human brain functional imaging. The modeling of light propagation, also known as the forward problem, is the computational bottleneck of the recovery algorithm, whereby the lack of a real-time solution is impeding practical and clinical applications. The objective of this work is the acceleration of the forward model, within a diffusion approximation-based finite-element modeling framework, employing parallelization to expedite the calculation of light propagation in realistic adult head models. The proposed methodology is applicable for modeling both continuous wave and frequency-domain systems with the results demonstrating a 10-fold speed increase when GPU architectures are available, while maintaining high accuracy. It is shown that, for a very high-resolution finite-element model of the adult human head with ˜600,000 nodes, consisting of heterogeneous layers, light propagation can be calculated at ˜0.25 s/excitation source.
NASA Astrophysics Data System (ADS)
Parviainen, Hannu
2015-10-01
PyLDTk automates the calculation of custom stellar limb darkening (LD) profiles and model-specific limb darkening coefficients (LDC) using the library of PHOENIX-generated specific intensity spectra by Husser et al. (2013). It facilitates exoplanet transit light curve modeling, especially transmission spectroscopy where the modeling is carried out for custom narrow passbands. PyLDTk construct model-specific priors on the limb darkening coefficients prior to the transit light curve modeling. It can also be directly integrated into the log posterior computation of any pre-existing transit modeling code with minimal modifications to constrain the LD model parameter space directly by the LD profile, allowing for the marginalization over the whole parameter space that can explain the profile without the need to approximate this constraint by a prior distribution. This is useful when using a high-order limb darkening model where the coefficients are often correlated, and the priors estimated from the tabulated values usually fail to include these correlations.
The JCMT Gould Belt Survey: A First Look at SCUBA-2 Observations of the Lupus I Molecular Cloud
NASA Astrophysics Data System (ADS)
Mowat, C.; Hatchell, J.; Rumble, D.; Kirk, H.; Buckle, J.; Berry, D. S.; Broekhoven-Fiene, H.; Currie, M. J.; Jenness, T.; Johnstone, D.; Mottram, J. C.; Pattle, K.; Tisi, S.; Di Francesco, J.; Hogerheijde, M. R.; Ward-Thompson, D.; Bastien, P.; Bresnahan, D.; Butner, H.; Chen, M.; Chrysostomou, A.; Coudé, S.; Davis, C. J.; Drabek-Maunder, E.; Duarte-Cabral, A.; Fich, M.; Fiege, J.; Friberg, P.; Friesen, R.; Fuller, G. A.; Graves, S.; Greaves, J.; Holland, W.; Joncas, G.; Kirk, J. M.; Knee, L. B. G.; Mairs, S.; Marsh, K.; Matthews, B. C.; Moriarty-Schieven, G.; Rawlings, J.; Retter, B.; Richer, J.; Robertson, D.; Rosolowsky, E.; Sadavoy, S.; Thomas, H.; Tothill, N.; Viti, S.; White, G. J.; Wouterloot, J.; Yates, J.; Zhu, M.
2017-05-01
This paper presents observations of the Lupus I molecular cloud at 450 and 850 μm with Submillimetre Common User Bolometer Array (SCUBA-2) as part of the James Clerk Maxwell Telescope Gould Belt Survey (JCMT GBS). Nine compact sources, assumed to be the discs of young stellar objects (YSOs), 12 extended protostellar, pre-stellar and starless cores, and one isolated, low-luminosity protostar, are detected in the region. Spectral energy distributions, including submillimetre fluxes, are produced for 15 YSOs, and each is fitted with the models of Robitaille et al. The proportion of Class 0/I protostars is higher than that seen in other Gould Belt regions such as Ophiuchus and Serpens. Circumstellar disc masses are calculated for more evolved sources, while protostellar envelope masses are calculated for protostars. Up to four very low luminosity objects are found; a large fraction when compared to other Spitzer c2d regions. One YSO has a disc mass greater than the minimum mass solar nebula. 12 starless/protostellar cores are detected by SCUBA-2 and their masses are calculated. The stability of these cores is examined using both the thermal Jeans mass and a turbulent virial mass when possible. Two cores in Lupus I are super-Jeans and contain no known YSOs. One of these cores has a virial parameter of 1.1 ± 0.4, and could therefore be pre-stellar. The high ratio of Class 0/I to Class III YSOs (1:1), and the presence of a pre-stellar core candidate, provides support for the hypothesis that a shock recently triggered star formation in Lupus I.
Exposure to light enhances pre-adult fitness in two dark-dwelling sympatric species of ants
Lone, Shahnaz Rahman; Sharma, Vijay Kumar
2008-01-01
Background In insects, circadian clocks play a key role in enhancing fitness by regulating life history traits such as developmental time and adult lifespan. These clocks use environmental light/dark (LD) cycles to fine-tune a wide range of behavioral and physiological processes. To study the effect of environmental LD conditions on pre-adult fitness components, we used two dark-dwelling sympatric species of ants (the night active Camponotus compressus and the day active Camponotus paria), which normally develop underground and have fairly long pre-adult developmental time. Results Our results suggest that ants develop fastest as pre-adults when maintained under constant light (LL), followed closely by 12:12 hr light/dark (LD), and then constant darkness (DD). While light exposure alters developmental rates of almost all stages of development, the overall pre-adult development in LL is speeded-up (relative to DD) by ~37% (34 days) in C. compressus and by ~35% (31 days) in C. paria. In LD too, development is faster (relative to DD) by ~29% (26 days) in C. compressus and by ~28% (25 days) in C. paria. Pre-adult viability of both species is also higher under LL and LD compared to DD. While pre-adult development time and viability is enhanced in LL and LD, clutch-size undergoes reduction, at least in C. compressus. Conclusion Exposure to light enhances pre-adult fitness in two dark-dwelling species of Camponotus by speeding-up development and by enhancing viability. This suggests that social ants use environmental light/dark cycles to modulate key life history traits such as pre-adult development time and viability. PMID:19046462
The Rise and Fall of the Type Ib Supernova iPTF13bvn Not a Massive Wolf-Rayet Star
NASA Technical Reports Server (NTRS)
Fremling, C.; Sollerman, J.; Taddia, F.; Ergon, M.; Valenti, S.; Arcavi, I.; Ben-Ami, S.; Cao, Y.; Cenko, S. B.; Filippenko, A. V.;
2014-01-01
Context. We investigate iPTF13bvn, a core-collapse (CC) supernova (SN) in the nearby spiral galaxy NGC 5806. This object was discovered by the intermediate Palomar Transient Factory (iPTF) very close to the estimated explosion date and was classified as a stripped-envelope CC SN, likely of Type Ib. Furthermore, a possible progenitor detection in pre-explosion Hubble Space Telescope (HST) images was reported, making this the only SN Ib with such an identification. Based on the luminosity and color of the progenitor candidate, as well as on early-time spectra and photometry of the SN, it was argued that the progenitor candidate is consistent with a single, massive Wolf-Rayet (WR) star. Aims. We aim to confirm the progenitor detection, to robustly classify the SN using additional spectroscopy, and to investigate if our follow-up photometric and spectroscopic data on iPTF13bvn are consistent with a single-star WR progenitor scenario. Methods. We present a large set of observational data, consisting of multi-band light curves (UBVRI, g'r'i'z') and optical spectra. We perform standard spectral line analysis to track the evolution of the SN ejecta. We also construct a bolometric light curve and perform hydrodynamical calculations to model this light curve to constrain the synthesized radioactive nickel mass and the total ejecta mass of the SN. Late-time photometry is analyzed to constrain the amount of oxygen. Furthermore, image registration of pre- and post-explosion HST images is performed. Results. Our HST astrometry confirms the location of the progenitor candidate of iPTF13bvn, and follow-up spectra securely classify this as a SN Ib. We use our hydrodynamical model to fit the observed bolometric light curve, estimating the total ejecta mass to be 1.9 solar mass and the radioactive nickel mass to be 0.05 solar mass. The model fit requires the nickel synthesized in the explosion to be highly mixed out in the ejecta. We also find that the late-time nebular r'-band luminosity is not consistent with predictions based on the expected oxygen nucleosynthesis in very massive stars. Conclusions. We find that our bolometric light curve of iPTF13bvn is not consistent with the previously proposed single massive WR-star progenitor scenario. The total ejecta mass and, in particular, the late-time oxygen emission are both significantly lower than what would be expected from a single WR progenitor with a main-sequence mass of at least 30 solar mass.
NASA Technical Reports Server (NTRS)
Grams, G. W.
1982-01-01
A variety of studies were carried out to help establish the accuracy of quantities describing physical characteristics of cloud particles (such as size, shape, and composition) that are to be inferred from light scattering data obtained with the nephelameter experiment on the Galileo spacecraft. The objectives were to provide data for validating and testing procedures for analyzing the Galileo nephelameter data with light scattering observations in a variety of on-going laboratory and field measurement programs for which simultaneous observations of the physical characteristics of the scattering particles were available.
Mass loss from pre-main-sequence accretion disks. I - The accelerating wind of FU Orionis
NASA Technical Reports Server (NTRS)
Calvet, Nuria; Hartmann, Lee; Kenyon, Scott J.
1993-01-01
We present evidence that the wind of the pre-main-sequence object FU Orionis arises from the surface of the luminous accretion disk. A disk wind model calculated assuming radiative equilibrium explains the differential behavior of the observed asymmetric absorption-line profiles. The model predicts that strong lines should be asymmetric and blueshifted, while weak lines should be symmetric and double-peaked due to disk rotation, in agreement with observations. We propose that many blueshifted 'shell' absorption features are not produced in a true shell of material, but rather form in a differentially expanding wind that is rapidly rotating. The inference of rapid rotation supports the proposal that pre-main-sequence disk winds are rotationally driven.
Phytochrome A Mediates Blue-Light Enhancement of Second-Positive Phototropism in Arabidopsis
Sullivan, Stuart; Hart, Jaynee E.; Rasch, Patrick; Walker, Catriona H.; Christie, John M.
2016-01-01
Hypocotyl phototropism of etiolated Arabidopsis seedlings is primarily mediated by the blue-light receptor kinase phototropin 1 (phot1). Phot1-mediated curvature to continuous unilateral blue light irradiation (0.5 μmol m−2 s−1) is enhanced by overhead pre-treatment with red light (20 μmol m−2 s−1 for 15 min) through the action of phytochrome (phyA). Here, we show that pre-treatment with blue light is equally as effective in eliciting phototropic enhancement and is dependent on phyA. Although blue light pre-treatment was sufficient to activate early phot1 signaling events, phot1 autophosphorylation in vivo was not found to be saturated, as assessed by subsequently measuring phot1 kinase activity in vitro. However, enhancement effects by red and blue light pre-treatment were not observed at higher intensities of phototropic stimulation (10 μmol m−2 s−1). Phototropic enhancement by red and blue light pre-treatments to 0.5 μmol m−2 s−1 unilateral blue light irradiation was also lacking in transgenic Arabidopsis where PHOT1 expression was restricted to the epidermis. Together, these findings indicate that phyA-mediated effects on phot1 signaling are restricted to low intensities of phototropic stimulation and originate from tissues other than the epidermis. PMID:27014313
Phytochrome A Mediates Blue-Light Enhancement of Second-Positive Phototropism in Arabidopsis.
Sullivan, Stuart; Hart, Jaynee E; Rasch, Patrick; Walker, Catriona H; Christie, John M
2016-01-01
Hypocotyl phototropism of etiolated Arabidopsis seedlings is primarily mediated by the blue-light receptor kinase phototropin 1 (phot1). Phot1-mediated curvature to continuous unilateral blue light irradiation (0.5 μmol m(-2) s(-1)) is enhanced by overhead pre-treatment with red light (20 μmol m(-2) s(-1) for 15 min) through the action of phytochrome (phyA). Here, we show that pre-treatment with blue light is equally as effective in eliciting phototropic enhancement and is dependent on phyA. Although blue light pre-treatment was sufficient to activate early phot1 signaling events, phot1 autophosphorylation in vivo was not found to be saturated, as assessed by subsequently measuring phot1 kinase activity in vitro. However, enhancement effects by red and blue light pre-treatment were not observed at higher intensities of phototropic stimulation (10 μmol m(-2) s(-1)). Phototropic enhancement by red and blue light pre-treatments to 0.5 μmol m(-2) s(-1) unilateral blue light irradiation was also lacking in transgenic Arabidopsis where PHOT1 expression was restricted to the epidermis. Together, these findings indicate that phyA-mediated effects on phot1 signaling are restricted to low intensities of phototropic stimulation and originate from tissues other than the epidermis.
Proportional Counter Calibration and Analysis for 12C + p Resonance Scattering
NASA Astrophysics Data System (ADS)
Nelson, Austin; Rogachev, Grigory; Uberseder, Ethan; Hooker, Josh; Koshchiy, Yevgen
2014-09-01
Light exotic nuclei provide a unique opportunity to test the predictions of modern ab initio theoretical calculations near the drip line. In ab initio approaches, nuclear structure is described starting from bare nucleon-nucleon and three-nucleon interactions. Calculations are very heavy and can only be performed for the lightest nuclei (A < 16). Experimental information on the structure of light exotic nuclei is crucial to determine the validity of these calculations and to fix the parameters for the three-nucleon forces. Resonance scattering with rare isotope beams is a very effective tool to study spectroscopy of nuclei near the drip line. A new setup was developed at the Cyclotron Institute for effective resonance scattering measurements. The setup includes ionization chamber, silicon array, and an array of proportional counters. The proportional counter array, consisting of 8 anode wires arranged in a parallel cellular grid, is used for particle identification and to track the positioning of light recoils. The main objective of this project was to test the performance and perform position calibration of this proportional counter array. The test was done using 12C beam. The excitation function for 12C + p elastic scattering was measured and calibration of the proportional counter was performed using known resonances in 13N. The method of calibration, including solid angle calculations, normalization corrections, and position calibration will be presented. Light exotic nuclei provide a unique opportunity to test the predictions of modern ab initio theoretical calculations near the drip line. In ab initio approaches, nuclear structure is described starting from bare nucleon-nucleon and three-nucleon interactions. Calculations are very heavy and can only be performed for the lightest nuclei (A < 16). Experimental information on the structure of light exotic nuclei is crucial to determine the validity of these calculations and to fix the parameters for the three-nucleon forces. Resonance scattering with rare isotope beams is a very effective tool to study spectroscopy of nuclei near the drip line. A new setup was developed at the Cyclotron Institute for effective resonance scattering measurements. The setup includes ionization chamber, silicon array, and an array of proportional counters. The proportional counter array, consisting of 8 anode wires arranged in a parallel cellular grid, is used for particle identification and to track the positioning of light recoils. The main objective of this project was to test the performance and perform position calibration of this proportional counter array. The test was done using 12C beam. The excitation function for 12C + p elastic scattering was measured and calibration of the proportional counter was performed using known resonances in 13N. The method of calibration, including solid angle calculations, normalization corrections, and position calibration will be presented. Funded by DOE and NSF-REU Program; Grant No. PHY-1263281.
Measurement and application of bidirectional reflectance distribution function
NASA Astrophysics Data System (ADS)
Liao, Fei; Li, Lin; Lu, Chengwen
2016-10-01
When a beam of light with certain intensity and distribution reaches the surface of a material, the distribution of the diffused light is related to the incident angle, the receiving angle, the wavelength of the light and the types of the material. Bidirectional Reflectance Distribution Function (BRDF) is a method to describe this distribution. For an optical system, the optical and mechanical materials' BRDF are unique, and if we want to calculate stray light of the system we should know the correct BRDF data of the whole materials. There are fundamental significances in the area of space remote sensor where BRDF is needed in the precise radiation calibration. It is also important in the military field where BRDF can be used in the object identification and target tracking, etc. In this paper, 11 kinds of aerospace materials' BRDF are measured and more than 310,000 groups of BRDF data are achieved , and also a BRDF database is established in China for the first time. With the BRDF data of the database, we can create the detector model, build the stray light radiation surface model in the stray light analysis software. In this way, the stray radiation on the detector can be calculated correctly.
Distributed learning and multi-objectivity in traffic light control
NASA Astrophysics Data System (ADS)
Brys, Tim; Pham, Tong T.; Taylor, Matthew E.
2014-01-01
Traffic jams and suboptimal traffic flows are ubiquitous in modern societies, and they create enormous economic losses each year. Delays at traffic lights alone account for roughly 10% of all delays in US traffic. As most traffic light scheduling systems currently in use are static, set up by human experts rather than being adaptive, the interest in machine learning approaches to this problem has increased in recent years. Reinforcement learning (RL) approaches are often used in these studies, as they require little pre-existing knowledge about traffic flows. Distributed constraint optimisation approaches (DCOP) have also been shown to be successful, but are limited to cases where the traffic flows are known. The distributed coordination of exploration and exploitation (DCEE) framework was recently proposed to introduce learning in the DCOP framework. In this paper, we present a study of DCEE and RL techniques in a complex simulator, illustrating the particular advantages of each, comparing them against standard isolated traffic actuated signals. We analyse how learning and coordination behave under different traffic conditions, and discuss the multi-objective nature of the problem. Finally we evaluate several alternative reward signals in the best performing approach, some of these taking advantage of the correlation between the problem-inherent objectives to improve performance.
Multi-Filter Photometric Analysis of Three β Lyrae-type Eclipsing Binary Stars
NASA Astrophysics Data System (ADS)
Gardner, T.; Hahs, G.; Gokhale, V.
2015-12-01
We present light curve analysis of three variable stars, ASAS J105855+1722.2, NSVS 5066754, and NSVS 9091101. These objects are selected from a list of β- Lyrae candidates published by Hoffman et al. (2008). Light curves are generated using data collected at the the 31-inch NURO telescope at the Lowell Observatory in Flagstaff, Arizona in three filters: Bessell B, V, and R. Additional observations were made using the 14-inch Meade telescope at the Truman State Observatory in Kirksville, Missouri using Baader R, G, and B filters. In this paper, we present the light curves for these three objects and generate a truncated eight-term Fourier fit to these light curves. We use the Fourier coefficients from this fit to confirm ASAS J105855+1722.2 and NSVS 5066754 as β Lyrae type systems, and NSVS 9091101 to possibly be a RR Lyrae-type system. We measure the O'Connell effect observed in two of these systems (ASAS J105855+1722.2 and NSVS 5066754), and quantify this effect by calculating the "Light Curve Asymmetry" (LCA) and the "O'Connell Effect Ratio" (OER).
NASA Astrophysics Data System (ADS)
Gritsevich, M.; Penttilä, A.; Maconi, G.; Kassamakov, I.; Martikainen, J.; Markkanen, J.; Vaisanen, T.; Helander, P.; Puranen, T.; Salmi, A.; Hæggström, E.; Muinonen, K.
2017-12-01
Electromagnetic scattering is a fundamental physical process that allows inferring characteristics of an object studied remotely. This possibility is enhanced by obtaining the light-scattering response at multiple wavelengths and viewing geometries, i.e., by considering a wider range of the phase angle (the angle between the incident light and the light reflected from the object) in the experiment. Within the ERC Advanced Grant project SAEMPL (http://cordis.europa.eu/project/rcn/107666_en.html) we have assembled an interdisciplinary group of scientists to develop a fully automated, 3D scatterometer that can measure scattered light at different wavelengths from small particulate samples. The setup comprises: (a) the PXI Express platform to synchronously record data from several photomultiplier tubes (PMTs); (b) a motorized rotation stage to precisely control the azimuthal angle of the PMTs around 360°; and (c) a versatile light source, whose wavelength, polarization, intensity, and beam shape can be precisely controlled. An acoustic levitator is used to hold the sample without touching it. The device is the first of its kind, since it measures controlled spectral angular scattering including all polarization effects, for an arbitrary object in the µm-cm size scale. It permits a nondestructive, disturbance-free measurement with control of the orientation and location of the scattering object. To demonstrate our approach we performed detailed measurements of light scattered by a Chelyabinsk LL5 chondrite particle, derived from the light-colored lithology sample of the meteorite. These measurements are cross-validated against the modeled light-scattering characteristics of the sample, i.e., the intensity and the degree of linear polarization of the reflected light, calculated with state-of-the-art electromagnetic techniques (see Muinonen et al., this meeting). We demonstrate a unique non-destructive approach to derive the optical properties of small grain samples which facilitates research on highly valuable planetary materials, such as samples returned from space missions or rare meteorites.
Bolometric Light Curves of Peculiar Type II-P Supernovae
NASA Astrophysics Data System (ADS)
Lusk, Jeremy A.; Baron, E.
2017-04-01
We examine the bolometric light curves of five Type II-P supernovae (SNe 1998A, 2000cb, 2006V, 2006au, and 2009E), which are thought to originate from blue supergiant progenitors like that of SN 1987A, using a new python package named SuperBoL. With this code, we calculate SNe light curves using three different common techniques common from the literature: the quasi-bolometric method, which integrates the observed photometry, the direct integration method, which additionally corrects for unobserved flux in the UV and IR, and the bolometric correction method, which uses correlations between observed colors and V-band bolometric corrections. We present here the light curves calculated by SuperBoL, along with previously published light curves, as well as peak luminosities and 56Ni yields. We find that the direct integration and bolometric correction light curves largely agree with previously published light curves, but with what we believe to be more robust error calculations, with 0.2≲ δ {L}{bol}/{L}{bol}≲ 0.5. Peak luminosities and 56Ni masses are similarly comparable to previous work. SN 2000cb remains an unusual member of this sub-group, owing to the faster rise and flatter plateau than the other supernovae in the sample. Initial comparisons with the NLTE atmosphere code PHOENIX show that the direct integration technique reproduces the luminosity of a model supernova spectrum to ˜5% when given synthetic photometry of the spectrum as input. Our code is publicly available. The ability to produce bolometric light curves from observed sets of broadband light curves should be helpful in the interpretation of other types of supernovae, particularly those that are not well characterized, such as extremely luminous supernovae and faint fast objects.
NASA Astrophysics Data System (ADS)
Gong, Changfei; Han, Ce; Gan, Guanghui; Deng, Zhenxiang; Zhou, Yongqiang; Yi, Jinling; Zheng, Xiaomin; Xie, Congying; Jin, Xiance
2017-04-01
Dynamic myocardial perfusion CT (DMP-CT) imaging provides quantitative functional information for diagnosis and risk stratification of coronary artery disease by calculating myocardial perfusion hemodynamic parameter (MPHP) maps. However, the level of radiation delivered by dynamic sequential scan protocol can be potentially high. The purpose of this work is to develop a pre-contrast normal-dose scan induced structure tensor total variation regularization based on the penalized weighted least-squares (PWLS) criteria to improve the image quality of DMP-CT with a low-mAs CT acquisition. For simplicity, the present approach was termed as ‘PWLS-ndiSTV’. Specifically, the ndiSTV regularization takes into account the spatial-temporal structure information of DMP-CT data and further exploits the higher order derivatives of the objective images to enhance denoising performance. Subsequently, an effective optimization algorithm based on the split-Bregman approach was adopted to minimize the associative objective function. Evaluations with modified dynamic XCAT phantom and preclinical porcine datasets have demonstrated that the proposed PWLS-ndiSTV approach can achieve promising gains over other existing approaches in terms of noise-induced artifacts mitigation, edge details preservation, and accurate MPHP maps calculation.
NASA Astrophysics Data System (ADS)
Hoadley, Keri; France, Kevin; Nell, Nicholas; Kane, Robert; Schultz, Ted; Beasley, Matthew; Green, James; Kulow, Jen; Kersgaard, Eliot; Fleming, Brian
2014-07-01
The Colorado High-resolution Echelle Stellar Spectrograph (CHESS) is a far ultraviolet (FUV) rocket-borne experiment designed to study the atomic-to-molecular transitions within translucent interstellar clouds. CHESS is an objective echelle spectrograph operating at f/12.4 and resolving power of 120,000 over a band pass of 100 - 160 nm. The echelle flight grating is the product of a research and development project with LightSmyth Inc. and was coated at Goddard Space Flight Center (GSFC) with Al+LiF. It has an empirically-determined groove density of 71.67 grooves/mm. At the Center for Astrophysics and Space Astronomy (CASA) at the University of Colorado (CU), we measured the efficiencies of the peak and adjacent dispersion orders throughout the 90 - 165 nm band pass to characterize the behavior of the grating for pre-flight calibrations and to assess the scattered-light behavior. The crossdispersing grating, developed and ruled by Horiba Jobin-Yvon, is a holographically-ruled, low line density (351 grooves/mm), powered optic with a toroidal surface curvature. The CHESS cross-disperser was also coated at GSFC; Cr+Al+LiF was deposited to enhance far-UV efficiency. Results from final efficiency and reflectivity measurements of both optics are presented. We utilize a cross-strip anode microchannel plate (MCP) detector built by Sensor Sciences to achieve high resolution (25 μm spatial resolution) and data collection rates (~ 106 photons/second) over a large format (40mm round, digitized to 8k x 8k) for the first time in an astronomical sounding rocket flight. The CHESS instrument was successfully launched from White Sands Missile Range on 24 May 2014. We present pre-flight sensitivity, effective area calculations, lab spectra and calibration results, and touch on first results and post-flight calibration plans.
An accelerated hologram calculation using the wavefront recording plane method and wavelet transform
NASA Astrophysics Data System (ADS)
Arai, Daisuke; Shimobaba, Tomoyoshi; Nishitsuji, Takashi; Kakue, Takashi; Masuda, Nobuyuki; Ito, Tomoyoshi
2017-06-01
Fast hologram calculation methods are critical in real-time holography applications such as three-dimensional (3D) displays. We recently proposed a wavelet transform-based hologram calculation called WASABI. Even though WASABI can decrease the calculation time of a hologram from a point cloud, it increases the calculation time with increasing propagation distance. We also proposed a wavefront recoding plane (WRP) method. This is a two-step fast hologram calculation in which the first step calculates the superposition of light waves emitted from a point cloud in a virtual plane, and the second step performs a diffraction calculation from the virtual plane to the hologram plane. A drawback of the WRP method is in the first step when the point cloud has a large number of object points and/or a long distribution in the depth direction. In this paper, we propose a method combining WASABI and the WRP method in which the drawbacks of each can be complementarily solved. Using a consumer CPU, the proposed method succeeded in performing a hologram calculation with 2048 × 2048 pixels from a 3D object with one million points in approximately 0.4 s.
NASA Astrophysics Data System (ADS)
Vo, Martin
2017-08-01
Light Curves Classifier uses data mining and machine learning to obtain and classify desired objects. This task can be accomplished by attributes of light curves or any time series, including shapes, histograms, or variograms, or by other available information about the inspected objects, such as color indices, temperatures, and abundances. After specifying features which describe the objects to be searched, the software trains on a given training sample, and can then be used for unsupervised clustering for visualizing the natural separation of the sample. The package can be also used for automatic tuning parameters of used methods (for example, number of hidden neurons or binning ratio). Trained classifiers can be used for filtering outputs from astronomical databases or data stored locally. The Light Curve Classifier can also be used for simple downloading of light curves and all available information of queried stars. It natively can connect to OgleII, OgleIII, ASAS, CoRoT, Kepler, Catalina and MACHO, and new connectors or descriptors can be implemented. In addition to direct usage of the package and command line UI, the program can be used through a web interface. Users can create jobs for ”training” methods on given objects, querying databases and filtering outputs by trained filters. Preimplemented descriptors, classifier and connectors can be picked by simple clicks and their parameters can be tuned by giving ranges of these values. All combinations are then calculated and the best one is used for creating the filter. Natural separation of the data can be visualized by unsupervised clustering.
Exquisite Nova Light Curves from the Solar Mass Ejection Imager (SMEI)
NASA Astrophysics Data System (ADS)
Hounsell, R.; Bode, M. F.; Hick, P. P.; Buffington, A.; Jackson, B. V.; Clover, J. M.; Shafter, A. W.; Darnley, M. J.; Mawson, N. R.; Steele, I. A.; Evans, A.; Eyres, S. P. S.; O'Brien, T. J.
2010-11-01
We present light curves of three classical novae (CNe; KT Eridani, V598 Puppis, V1280 Scorpii) and one recurrent nova (RS Ophiuchi) derived from data obtained by the Solar Mass Ejection Imager (SMEI) on board the Coriolis satellite. SMEI provides near complete skymap coverage with precision visible-light photometry at 102 minute cadence. The light curves derived from these skymaps offer unprecedented temporal resolution around, and especially before, maximum light, a phase of the eruption normally not covered by ground-based observations. They allow us to explore fundamental parameters of individual objects including the epoch of the initial explosion, the reality and duration of any pre-maximum halt (found in all three fast novae in our sample), the presence of secondary maxima, speed of decline of the initial light curve, plus precise timing of the onset of dust formation (in V1280 Sco) leading to estimation of the bolometric luminosity, white dwarf mass, and object distance. For KT Eri, Liverpool Telescope SkyCamT data confirm important features of the SMEI light curve and overall our results add weight to the proposed similarities of this object to recurrent rather than to CNe. In RS Oph, comparison with hard X-ray data from the 2006 outburst implies that the onset of the outburst coincides with extensive high-velocity mass loss. It is also noted that two of the four novae we have detected (V598 Pup and KT Eri) were only discovered by ground-based observers weeks or months after maximum light, yet these novae reached peak magnitudes of 3.46 and 5.42, respectively. This emphasizes the fact that many bright novae per year are still overlooked, particularly those of the very fast speed class. Coupled with its ability to observe novae in detail even when relatively close to the Sun in the sky, we estimate that as many as five novae per year may be detectable by SMEI.
Statistical theory of light nucleus reactions with 1p-shell light nuclei
NASA Astrophysics Data System (ADS)
Xiaojun, Sun; Jingshang, Zhang
2017-09-01
The 1p-shell light elements (Li, Be, B, C, N, and O) had long been selected as the most important materials for improving neutron economy in thermal and fast fission reactors and in the design of accelerator-driven spallation neutron sources. A statistical theory of light nucleus reactions (STLN) is proposed to describe the double-differential cross sections for both neutron and light charged particle induced nuclear reactions with 1p-shell light nuclei. The dynamics of STLN is described by the unified Hauser-Feshbach and exciton model, in which the angular momentum and parity conservations are strictly considered in equilibrium and pre-equilibrium processes. The Coulomb barriers of the incoming and outgoing charged particles, which significantly influence the open channels of the reaction, can be reasonably considered in incident channel and different outgoing channels. In kinematics, the recoiling effects in various emission processes are strictly taken into account. The analytical energy and angular spectra of the reaction products in sequential and simultaneous emission processes are obtained in terms of the new integral formula proposed in our recent paper. Taking 12C(n, xn), 9Be(n, xn), 16O(n, xn), and 9Be(p,xn) reactions as examples, we had calculated the double-differential cross sections of outgoing neutrons and compared with the experimental data. In addition, we had also calculated the partition and total kerma coefficients for 12C(n, xn) and 16O(n, xn) reactions, respectively. The existing experimental data can be remarkably well reproduced by STLN, which had been used to set up file-6 in CENDL database.
Gurav, Sushma K.; Zirpe, Kapil G.; Wadia, R. S.; Naniwadekar, Avinash; Pote, Prajakta U.; Tungenwar, Amit; Deshmukh, Abhijeet M.; Mohopatra, Srikanta; Nimavat, Balakrishna; Surywanshi, Prasad
2018-01-01
Objective: “Stroke code” (SC) implementation in hospitals can improve the rate of thrombolysis and the timeline in care of stroke patient. Materials and Methods: A prospective data of patients treated for acute ischemic stroke (AIS) after implementation of “SC” (post-SC era) were analyzed (2015–2016) and compared with the retrospective data of patients treated in the “pre-SC era.” Parameters such as symptom-to-door, door-to-physician, door-to-imaging, door-to-needle (DTN), and symptom-to-needle time were calculated. The severity of stroke was calculated using the National Institutes of Health Stroke Score (NIHSS) before and after treatment. Results: Patients presented with stroke symptoms in pre- and post-SC era (695 vs. 610) and, out of these, patients who came in window period constituted 148 (21%) and 210 (34%), respectively. Patients thrombolyzed in pre- and post-SC era were 44 (29.7%) and 65 (44.52%), respectively. Average DTN time was 104.95 min in pre-SC era and reduced to 67.28 min (P < 0.001) post-SC implementation. Percentage of patients thrombolyzed within DTN time ≤60 min in pre-SC era and SC era was 15.90% and 55.38%, respectively. Conclusion: Implementation of SC helped us to increase thrombolysis rate in AIS and decrease DTN time. PMID:29743763
NASA Astrophysics Data System (ADS)
Markman, Adam; Carnicer, Artur; Javidi, Bahram
2017-05-01
We overview our recent work [1] on utilizing three-dimensional (3D) optical phase codes for object authentication using the random forest classifier. A simple 3D optical phase code (OPC) is generated by combining multiple diffusers and glass slides. This tag is then placed on a quick-response (QR) code, which is a barcode capable of storing information and can be scanned under non-uniform illumination conditions, rotation, and slight degradation. A coherent light source illuminates the OPC and the transmitted light is captured by a CCD to record the unique signature. Feature extraction on the signature is performed and inputted into a pre-trained random-forest classifier for authentication.
WE-A-BRE-01: Debate: To Measure or Not to Measure
DOE Office of Scientific and Technical Information (OSTI.GOV)
Moran, J; Miften, M; Mihailidis, D
2014-06-15
Recent studies have highlighted some of the limitations of patient-specific pre-treatment IMRT QA measurements with respect to assessing plan deliverability. Pre-treatment QA measurements are frequently performed with detectors in phantoms that do not involve any patient heterogeneities or with an EPID without a phantom. Other techniques have been developed where measurement results are used to recalculate the patient-specific dose volume histograms. Measurements continue to play a fundamental role in understanding the initial and continued performance of treatment planning and delivery systems. Less attention has been focused on the role of computational techniques in a QA program such as calculation withmore » independent dose calculation algorithms or recalculation of the delivery with machine log files or EPID measurements. This session will explore the role of pre-treatment measurements compared to other methods such as computational and transit dosimetry techniques. Efficiency and practicality of the two approaches will also be presented and debated. The speakers will present a history of IMRT quality assurance and debate each other regarding which types of techniques are needed today and for future quality assurance. Examples will be shared of situations where overall quality needed to be assessed with calculation techniques in addition to measurements. Elements where measurements continue to be crucial such as for a thorough end-to-end test involving measurement will be discussed. Operational details that can reduce the gamma tool effectiveness and accuracy for patient-specific pre-treatment IMRT/VMAT QA will be described. Finally, a vision for the future of IMRT and VMAT plan QA will be discussed from a safety perspective. Learning Objectives: Understand the advantages and limitations of measurement and calculation approaches for pre-treatment measurements for IMRT and VMAT planning Learn about the elements of a balanced quality assurance program involving modulated techniques Learn how to use tools and techniques such as an end-to-end test to enhance your IMRT and VMAT QA program.« less
A clustering approach to segmenting users of internet-based risk calculators.
Harle, C A; Downs, J S; Padman, R
2011-01-01
Risk calculators are widely available Internet applications that deliver quantitative health risk estimates to consumers. Although these tools are known to have varying effects on risk perceptions, little is known about who will be more likely to accept objective risk estimates. To identify clusters of online health consumers that help explain variation in individual improvement in risk perceptions from web-based quantitative disease risk information. A secondary analysis was performed on data collected in a field experiment that measured people's pre-diabetes risk perceptions before and after visiting a realistic health promotion website that provided quantitative risk information. K-means clustering was performed on numerous candidate variable sets, and the different segmentations were evaluated based on between-cluster variation in risk perception improvement. Variation in responses to risk information was best explained by clustering on pre-intervention absolute pre-diabetes risk perceptions and an objective estimate of personal risk. Members of a high-risk overestimater cluster showed large improvements in their risk perceptions, but clusters of both moderate-risk and high-risk underestimaters were much more muted in improving their optimistically biased perceptions. Cluster analysis provided a unique approach for segmenting health consumers and predicting their acceptance of quantitative disease risk information. These clusters suggest that health consumers were very responsive to good news, but tended not to incorporate bad news into their self-perceptions much. These findings help to quantify variation among online health consumers and may inform the targeted marketing of and improvements to risk communication tools on the Internet.
THE LOCATIONS OF SHORT GAMMA-RAY BURSTS AS EVIDENCE FOR COMPACT OBJECT BINARY PROGENITORS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fong, W.; Berger, E.
2013-10-10
We present a detailed investigation of Hubble Space Telescope rest-frame UV/optical observations of 22 short gamma-ray burst (GRB) host galaxies and sub-galactic environments. Utilizing the high angular resolution and depth of HST we characterize the host galaxy morphologies, measure precise projected physical and host-normalized offsets between the bursts and host centers, and calculate the locations of the bursts with respect to their host light distributions (rest-frame UV and optical). We calculate a median short GRB projected physical offset of 4.5 kpc, about 3.5 times larger than that for long GRBs, and find that ≈25% of short GRBs have offsets ofmore » ∼> 10 kpc. When compared to their host sizes, the median offset is 1.5 half-light radii (r{sub e} ), about 1.5 times larger than the values for long GRBs, core-collapse supernovae, and Type Ia supernovae. In addition, ≈20% of short GRBs having offsets of ∼> 5r{sub e} , and only ≈25% are located within 1r{sub e} . We further find that short GRBs severely under-represent their hosts' rest-frame optical and UV light, with ≈30%-45% of the bursts located in regions of their host galaxies that have no detectable stellar light, and ≈55% in the regions with no UV light. Therefore, short GRBs do not occur in regions of star formation or even stellar mass. This demonstrates that the progenitor systems of short GRBs must migrate from their birth sites to their eventual explosion sites, a signature of kicks in compact object binary systems. Utilizing the full sample of offsets, we estimate natal kick velocities of ≈20-140 km s{sup –1}. These independent lines of evidence provide the strongest support to date that short GRBs result from the merger of compact object binaries (NS-NS/NS-BH)« less
NASA Astrophysics Data System (ADS)
Chen, Liang-Chia; Chen, Yi-Shiuan; Chang, Yi-Wei; Lin, Shyh-Tsong; Yeh, Sheng Lih
2013-01-01
In this research, new nano-scale measurement methodology based on spectrally-resolved chromatic confocal interferometry (SRCCI) was successfully developed by employing integration of chromatic confocal sectioning and spectrally-resolve white light interferometry (SRWLI) for microscopic three dimensional surface profilometry. The proposed chromatic confocal method (CCM) using a broad band while light in combination with a specially designed chromatic dispersion objective is capable of simultaneously acquiring multiple images at a large range of object depths to perform surface 3-D reconstruction by single image shot without vertical scanning and correspondingly achieving a high measurement depth range up to hundreds of micrometers. A Linnik-type interferometric configuration based on spectrally resolved white light interferometry is developed and integrated with the CCM to simultaneously achieve nanoscale axis resolution for the detection point. The white-light interferograms acquired at the exit plane of the spectrometer possess a continuous variation of wavelength along the chromaticity axis, in which the light intensity reaches to its peak when the optical path difference equals to zero between two optical arms. To examine the measurement accuracy of the developed system, a pre-calibrated accurate step height target with a total step height of 10.10 μm was measured. The experimental result shows that the maximum measurement error was verified to be less than 0.3% of the overall measuring height.
Human phase response curve to a 1 h pulse of bright white light
St Hilaire, Melissa A; Gooley, Joshua J; Khalsa, Sat Bir S; Kronauer, Richard E; Czeisler, Charles A; Lockley, Steven W
2012-01-01
The phase resetting response of the human circadian pacemaker to light depends on the timing of exposure and is described by a phase response curve (PRC). The current study aimed to construct a PRC for a 1 h exposure to bright white light (∼8000 lux) and to compare this PRC to a <3 lux dim background light PRC. These data were also compared to a previously completed 6.7 h bright white light PRC and a <15 lux dim background light PRC constructed under similar conditions. Participants were randomized for exposure to 1 h of either bright white light (n= 18) or <3 lux dim background light (n= 18) scheduled at 1 of 18 circadian phases. Participants completed constant routine (CR) procedures in dim light (<3 lux) before and after the light exposure to assess circadian phase. Phase shifts were calculated as the difference in timing of dim light melatonin onset (DLMO) during pre- and post-stimulus CRs. Exposure to 1 h of bright white light induced a Type 1 PRC with a fitted peak-to-trough amplitude of 2.20 h. No discernible PRC was observed in the <3 lux dim background light PRC. The fitted peak-to-trough amplitude of the 1 h bright light PRC was ∼40% of that for the 6.7 h PRC despite representing only 15% of the light exposure duration, consistent with previous studies showing a non-linear duration–response function for the effects of light on circadian resetting. PMID:22547633
Human phase response curve to a 1 h pulse of bright white light.
St Hilaire, Melissa A; Gooley, Joshua J; Khalsa, Sat Bir S; Kronauer, Richard E; Czeisler, Charles A; Lockley, Steven W
2012-07-01
The phase resetting response of the human circadian pacemaker to light depends on the timing of exposure and is described by a phase response curve (PRC). The current study aimed to construct a PRC for a 1 h exposure to bright white light (∼8000 lux) and to compare this PRC to a <3 lux dim background light PRC. These data were also compared to a previously completed 6.7 h bright white light PRC and a <15 lux dim background light PRC constructed under similar conditions. Participants were randomized for exposure to 1 h of either bright white light (n=18) or <3 lux dim background light (n=18) scheduled at 1 of 18 circadian phases. Participants completed constant routine (CR) procedures in dim light (<3 lux) before and after the light exposure to assess circadian phase. Phase shifts were calculated as the difference in timing of dim light melatonin onset (DLMO) during pre- and post-stimulus CRs. Exposure to 1 h of bright white light induced a Type 1 PRC with a fitted peak-to-trough amplitude of 2.20 h. No discernible PRC was observed in the <3 lux dim background light PRC. The fitted peak-to-trough amplitude of the 1 h bright light PRC was ∼40% of that for the 6.7 h PRC despite representing only 15% of the light exposure duration, consistent with previous studies showing a non-linear duration–response function for the effects of light on circadian resetting.
A novel method for fast imaging of brain function, non-invasively, with light
NASA Astrophysics Data System (ADS)
Chance, Britton; Anday, Endla; Nioka, Shoko; Zhou, Shuoming; Hong, Long; Worden, Katherine; Li, C.; Murray, T.; Ovetsky, Y.; Pidikiti, D.; Thomas, R.
1998-05-01
Imaging of the human body by any non-invasive technique has been an appropriate goal of physics and medicine, and great success has been obtained with both Magnetic Resonance Imaging (MRI) and Positron Emission Tomography (PET) in brain imaging. Non-imaging responses to functional activation using near infrared spectroscopy of brain (fNIR) obtained in 1993 (Chance, et al. [1]) and in 1994 (Tamura, et al. [2]) are now complemented with images of pre-frontal and parietal stimulation in adults and pre-term neonates in this communication (see also [3]). Prior studies used continuous [4], pulsed [3] or modulated [5] light. The amplitude and phase cancellation of optical patterns as demonstrated for single source detector pairs affords remarkable sensitivity of small object detection in model systems [6]. The methods have now been elaborated with multiple source detector combinations (nine sources, four detectors). Using simple back projection algorithms it is now possible to image sensorimotor and cognitive activation of adult and pre- and full-term neonate human brain function in times < 30 sec and with two dimensional resolutions of < 1 cm in two dimensional displays. The method can be used in evaluation of adult and neonatal cerebral dysfunction in a simple, portable and affordable method that does not require immobilization, as contrasted to MRI and PET.
An MM and QM Study of Biomimetic Catalysis of Diels-Alder Reactions Using Cyclodextrins
Chen, Wei; Sun, Lipeng; Tang, Zhiye; Ali, Zulfikhar A.; Wong, Bryan M.; Chang, Chia-en A.
2018-01-01
We performed a computational investigation of the mechanism by which cyclodextrins (CDs) catalyze Diels-Alder reactions between 9-anthracenemethanol and N-cyclohexylmaleimide. Hydrogen bonds (Hbonds) between N-cyclohexylmaleimide and the hydroxyl groups of cyclodextrins were suggested to play an important role in this catalytic process. However, our free energy calculations and molecular dynamics simulations showed that these Hbonds are not stable, and quantum mechanical calculations suggested that the reaction is not promoted by these Hbonds. The binding of 9-anthracenemethanol and N-cyclohexylmaleimide to cyclodextrins was the key to the catalytic process. Cyclodextrins act as a container to hold the two reactants in the cavity, pre-organize them for the reactions, and thus reduce the entropy penalty to the activation free energy. Dimethyl-β-CD was a better catalyst for this specific reaction than β-CD because of its stronger van der Waals interaction with the pre-organized reactants and its better performance in reducing the activation energy. This computational work sheds light on the mechanism of the catalytic reaction by cyclodextrins and introduces new perspectives of supramolecular catalysis. PMID:29938117
Oh, Seungtaik; Jeong, Il Kwon
2015-11-16
We will introduce a new simple analytic formula of the Fourier coefficient of the 3D field distribution of a point light source to generate a cylindrical angular spectrum which captures the object wave in 360° in the 3D Fourier space. Conceptually, the cylindrical angular spectrum can be understood as a cylindrical version of the omnidirectional spectral approach of Sando et al. Our Fourier coefficient formula is based on an intuitive observation that a point light radiates uniformly in all directions. Our formula is defined over all frequency vectors lying on the entire sphere in the 3D Fourier space and is more natural and computationally more efficient for all around recording of the object wave than that of the previous omnidirectional spectral method. A generalized frequency-based occlusion culling method for an arbitrary complex object is also proposed to enhance the 3D quality of a hologram. As a practical application of the cylindrical angular spectrum, an interactive hologram example is presented together with implementation details.
Analysis of fundamental parameters for V477 Lyr
NASA Astrophysics Data System (ADS)
Shimansky, V. V.; Pozdnyakova, S. A.; Borisov, N. V.; Bikmaev, I. F.; Galeev, A. I.; Sakhibullin, N. A.; Spiridonova, O. I.
2008-06-01
We analyze the photometric and spectroscopic observations of the young pre-cataclysmic variable (pre-CV) V477 Lyr. The masses of both binary components have been corrected by analyzing their radial velocity curves. We show that agreement between the theoretical and observed light curves of the object is possible for several sets of its physical parameters corresponding to the chosen temperature of the primary component. The final parameters of V477 Lyr have been established by comparing observational data with evolutionary tracks for planetary nebula nuclei. The derived effective temperature of the O subdwarf is higher than that estimated by analyzing the object’s ultraviolet spectra by more than 10000 K. This is in agreement with the analogous results obtained previously for the young pre-CVs V664 Cas and UU Sge. The secondary component of V477 Lyr has been proven to have a more than 25-fold luminosity excess compared to main-sequence stars of similar mass. Comparison of the physical parameters for the cool stars in young pre-CVs indicates that their luminosities do not correlate with the masses of the objects. The observed luminosity excesses in such stars show a close correlation with the post-common-envelope lifetime of the systems and should be investigated within the framework of the theory of their relaxation to the state of main-sequence stars.
NASA Astrophysics Data System (ADS)
Zeng, Zhenxiang; Zheng, Huadong; Yu, Yingjie; Asundi, Anand K.
2017-06-01
A method for calculating off-axis phase-only holograms of three-dimensional (3D) object using accelerated point-based Fresnel diffraction algorithm (PB-FDA) is proposed. The complex amplitude of the object points on the z-axis in hologram plane is calculated using Fresnel diffraction formula, called principal complex amplitudes (PCAs). The complex amplitudes of those off-axis object points of the same depth can be obtained by 2D shifting of PCAs. In order to improve the calculating speed of the PB-FDA, the convolution operation based on fast Fourier transform (FFT) is used to calculate the holograms rather than using the point-by-point spatial 2D shifting of the PCAs. The shortest recording distance of the PB-FDA is analyzed in order to remove the influence of multiple-order images in reconstructed images. The optimal recording distance of the PB-FDA is also analyzed to improve the quality of reconstructed images. Numerical reconstructions and optical reconstructions with a phase-only spatial light modulator (SLM) show that holographic 3D display is feasible with the proposed algorithm. The proposed PB-FDA can also avoid the influence of the zero-order image introduced by SLM in optical reconstructed images.
Paraboloid-aspheric lenses free of spherical aberration
NASA Astrophysics Data System (ADS)
Lozano-Rincón, Ninfa del C.; Valencia-Estrada, Juan Camilo
2017-07-01
A method to design singlet paraboloid-aspheric lenses free of all orders of spherical aberration with maximum aperture is described. This work includes all parametric formulas to describe paraboloid-aspheric or aspheric-paraboloid lenses for any finite conjugated planes. It also includes the Schwarzchilds approximations (which can be used to calculate one rigorous propagation of light waves in physic optics) to design convex paraboloid-aspheric lenses for imaging an object at infinity, with explicit formulas to calculate thicknesses easily. The results were verified with software through ray tracing.
Araki, Hiromitsu; Takada, Naoki; Niwase, Hiroaki; Ikawa, Shohei; Fujiwara, Masato; Nakayama, Hirotaka; Kakue, Takashi; Shimobaba, Tomoyoshi; Ito, Tomoyoshi
2015-12-01
We propose real-time time-division color electroholography using a single graphics processing unit (GPU) and a simple synchronization system of reference light. To facilitate real-time time-division color electroholography, we developed a light emitting diode (LED) controller with a universal serial bus (USB) module and the drive circuit for reference light. A one-chip RGB LED connected to a personal computer via an LED controller was used as the reference light. A single GPU calculates three computer-generated holograms (CGHs) suitable for red, green, and blue colors in each frame of a three-dimensional (3D) movie. After CGH calculation using a single GPU, the CPU can synchronize the CGH display with the color switching of the one-chip RGB LED via the LED controller. Consequently, we succeeded in real-time time-division color electroholography for a 3D object consisting of around 1000 points per color when an NVIDIA GeForce GTX TITAN was used as the GPU. Furthermore, we implemented the proposed method in various GPUs. The experimental results showed that the proposed method was effective for various GPUs.
Doulgerakis, Matthaios; Eggebrecht, Adam; Wojtkiewicz, Stanislaw; Culver, Joseph; Dehghani, Hamid
2017-12-01
Parameter recovery in diffuse optical tomography is a computationally expensive algorithm, especially when used for large and complex volumes, as in the case of human brain functional imaging. The modeling of light propagation, also known as the forward problem, is the computational bottleneck of the recovery algorithm, whereby the lack of a real-time solution is impeding practical and clinical applications. The objective of this work is the acceleration of the forward model, within a diffusion approximation-based finite-element modeling framework, employing parallelization to expedite the calculation of light propagation in realistic adult head models. The proposed methodology is applicable for modeling both continuous wave and frequency-domain systems with the results demonstrating a 10-fold speed increase when GPU architectures are available, while maintaining high accuracy. It is shown that, for a very high-resolution finite-element model of the adult human head with ∼600,000 nodes, consisting of heterogeneous layers, light propagation can be calculated at ∼0.25 s/excitation source. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).
A Framework for Realistic Modeling and Display of Object Surface Appearance
NASA Astrophysics Data System (ADS)
Darling, Benjamin A.
With advances in screen and video hardware technology, the type of content presented on computers has progressed from text and simple shapes to high-resolution photographs, photorealistic renderings, and high-definition video. At the same time, there have been significant advances in the area of content capture, with the development of devices and methods for creating rich digital representations of real-world objects. Unlike photo or video capture, which provide a fixed record of the light in a scene, these new technologies provide information on the underlying properties of the objects, allowing their appearance to be simulated for novel lighting and viewing conditions. These capabilities provide an opportunity to continue the computer display progression, from high-fidelity image presentations to digital surrogates that recreate the experience of directly viewing objects in the real world. In this dissertation, a framework was developed for representing objects with complex color, gloss, and texture properties and displaying them onscreen to appear as if they are part of the real-world environment. At its core, there is a conceptual shift from a traditional image-based display workflow to an object-based one. Instead of presenting the stored patterns of light from a scene, the objective is to reproduce the appearance attributes of a stored object by simulating its dynamic patterns of light for the real viewing and lighting geometry. This is accomplished using a computational approach where the physical light sources are modeled and the observer and display screen are actively tracked. Surface colors are calculated for the real spectral composition of the illumination with a custom multispectral rendering pipeline. In a set of experiments, the accuracy of color and gloss reproduction was evaluated by measuring the screen directly with a spectroradiometer. Gloss reproduction was assessed by comparing gonio measurements of the screen output to measurements of the real samples in the same measurement configuration. A chromatic adaptation experiment was performed to evaluate color appearance in the framework and explore the factors that contribute to differences when viewing self-luminous displays as opposed to reflective objects. A set of sample applications was developed to demonstrate the potential utility of the object display technology for digital proofing, psychophysical testing, and artwork display.
The influence of object pre-exposure on two-year-olds' disambiguation of novel labels.
Graham, Susan A; Turner, Juanita N; Henderson, Annette M E
2005-02-01
We investigated whether manipulating the perceived novelty of nameless objects would influence two-year-olds' tendency to map novel words to these objects. In Experiment 1, children who had been pre-exposed to target nameless objects were more likely to map novel words onto those objects than children who were not pre-exposed to the objects or children who were pre-exposed to non-target members of the nameless object categories. In Experiment 2, children who were pre-exposed to a nameless object were more likely to assign the novel label to that object than to either a familiar object or an unfamiliar object that had not been pre-exposed. The results of these studies suggest that reducing the novelty of nameless objects increases two-year-olds' tendency to map a novel word to a nameless object.
Blind guidance system based on laser triangulation
NASA Astrophysics Data System (ADS)
Wu, Jih-Huah; Wang, Jinner-Der; Fang, Wei; Lee, Yun-Parn; Shan, Yi-Chia; Kao, Hai-Ko; Ma, Shih-Hsin; Jiang, Joe-Air
2012-05-01
We propose a new guidance system for the blind. An optical triangulation method is used in the system. The main components of the proposed system comprise of a notebook computer, a camera, and two laser modules. The track image of the light beam on the ground or on the object is captured by the camera and then the image is sent to the notebook computer for further processing and analysis. Using a developed signal-processing algorithm, our system can determine the object width and the distance between the object and the blind person through the calculation of the light line positions on the image. A series of feasibility tests of the developed blind guidance system were conducted. The experimental results show that the distance between the test object and the blind can be measured with a standard deviation of less than 8.5% within the range of 40 and 130 cm, while the test object width can be measured with a standard deviation of less than 4.5% within the range of 40 and 130 cm. The application potential of the designed system to the blind guidance can be expected.
Kolling, William M; McPherson, Timothy B
2013-04-12
OBJECTIVE. To assess the effectiveness of using a vapor pressure osmometer to measure the accuracy of pharmacy students' compounding skills. DESIGN. Students calculated the theoretical osmotic pressure (mmol/kg) of a solution as a pre-laboratory exercise, compared their calculations with actual values, and then attempted to determine the cause of any errors found. ASSESSMENT. After the introduction of the vapor pressure osmometer, the first-time pass rate for solution compounding has varied from 85% to 100%. Approximately 85% of students surveyed reported that the instrument was valuable as a teaching tool because it objectively assessed their work and provided immediate formative assessment. CONCLUSIONS. This simple technique of measuring compounding accuracy using a vapor pressure osmometer allowed students to see the importance of quality control and assessment in practice for both pharmacists and technicians.
Assessment of the Accuracy of Pharmacy Students’ Compounded Solutions Using Vapor Pressure Osmometry
McPherson, Timothy B.
2013-01-01
Objective. To assess the effectiveness of using a vapor pressure osmometer to measure the accuracy of pharmacy students’ compounding skills. Design. Students calculated the theoretical osmotic pressure (mmol/kg) of a solution as a pre-laboratory exercise, compared their calculations with actual values, and then attempted to determine the cause of any errors found. Assessment. After the introduction of the vapor pressure osmometer, the first-time pass rate for solution compounding has varied from 85% to 100%. Approximately 85% of students surveyed reported that the instrument was valuable as a teaching tool because it objectively assessed their work and provided immediate formative assessment. Conclusions. This simple technique of measuring compounding accuracy using a vapor pressure osmometer allowed students to see the importance of quality control and assessment in practice for both pharmacists and technicians. PMID:23610476
Photometric Study of the Solar Type Pre-Contact Binary, V2421 Cygni
NASA Astrophysics Data System (ADS)
Hill, Robert L.; Shebs, T.; Samec, R. G.; Kring, J.; Van Hamme, W. V.; Faulkner, D. R.
2013-06-01
We present the first precision BVRI light curves, and synthetic light curve solutions and a period study for the 14th magnitude (V) pre-contact W UMa Binary, V2421 Cygni. Observations were taken with the NURO 0.81-m Lowell reflector on 30 September, 1 and 2 October. Our light curves were premodeled with Binary Maker 3.0, and solved with the Wilson-Devinney program. The observations included 140 B, 149 V, 139 R and 135 I individual and calibrated observations. These were taken with the Lowell CRYOTIGER cooled (-100k) 2KX2K NASACAM. Three mean times of minimum light were determined, including HJDMin I = 2455469.82375±0.00037, and 2455471.72232±0.0012 and HJDMin II = 2455470.77149±0.0012. Eight eclipse timings were taken from the the literature for our calculation of its first precision ephemeris: JD Tmin I = 2455469.8238± 0.0047 + 0.6331290 ± 0.0000015 d*E The light curve has the appearance of an Algol (EA) type, however it is made up of dwarf solar type components in a detached mode with a period of only 0.6331 days. The light curve solution gives a mass ratio of ~0.5, an inclination of 86° and amplitudes of 1.3, 1.1, 0.98, and 0.87 in B,V,R and I, respectively. Flare-like disruptions occur in the light curves following the primary and secondary eclipses. The fill-outs are 83% and 98% for star one (hotter more massive component) and star two, respectively. The model includes two hot spots, possibly, stream spots (one a direct hit and the second, a splash spot). Further observations are needed to determine its orbital evolution. We thank USC, Lancaster for their support of our membership in NURO for the past 8 years, the American Astronomical Society for its support through its small research program and Arizona Space grant for the partial support for our student’s travel.
Blue-Light Hazard From Gas Metal Arc Welding of Aluminum Alloys.
Nakashima, Hitoshi; Takahashi, Jyunya; Fujii, Nobuyuki; Okuno, Tsutomu
2017-10-01
The objective was to quantify the blue-light hazard from gas metal arc welding (GMAW) of aluminum alloys. The exposure level is expected to depend on the welding conditions. Therefore, it is important to identify the blue-light hazard under various welding conditions. We experimentally conducted GMAW of aluminum alloys under various welding conditions and measured the spectral radiance of the arcs. The effective blue-light radiance, which the American Conference of Governmental Industrial Hygienists has defined to quantify the exposure level of blue light, was calculated from the measured spectral radiance. The maximum acceptable exposure duration per 10000 s for this effective blue-light radiance was calculated. The effective blue-light radiance measured in this study was in the range of 2.9-20.0 W cm-2·sr. The corresponding maximum acceptable exposure duration per 10000 s was only 5.0-34 s, so it is hazardous to view the welding arc. The effective blue-light radiance was higher at higher welding currents than at lower welding currents, when pulsed welding currents were used rather than steady welding currents, and when magnesium was included in the welding materials. It is very hazardous to view the arcs in GMAW of aluminum alloys. Welders and their helpers should use appropriate eye protection in arc-welding operations. They should also avoid direct light exposure when starting an arc-welding operation. © The Author 2017. Published by Oxford University Press on behalf of the British Occupational Hygiene Society.
NASA Astrophysics Data System (ADS)
Chen, Liang-Chia; Chang, Yi-Wei; Li, Hau-Wei
2012-08-01
Full-field chromatic confocal surface profilometry employing a digital micromirror device (DMD) for spatial correspondence is proposed to minimize lateral cross-talks between individual detection sensors. Although full-field chromatic confocal profilometry is capable of enhancing measurement efficiency by completely removing time-consuming vertical scanning operation, its vertical measurement resolution and accuracy are still severely affected by the potential sensor lateral cross-talk problem. To overcome this critical bottleneck, a DMD-based chromatic confocal method is developed by employing a specially-designed objective for chromatic light dispersion, and a DMD for lateral pixel correspondence and scanning, thereby reducing the lateral cross-talk influence. Using the chromatic objective, the incident light is dispersed according to a pre-designed detection range of several hundred micrometers, and a full-field reflected light is captured by a three-chip color camera for multi color detection. Using this method, the full width half maximum of the depth response curve can be significantly sharpened, thus improving the vertical measurement resolution and repeatability of the depth detection. From our preliminary experimental evaluation, it is verified that the ±3σ repeatability of the height measurement can be kept within 2% of the overall measurement range.
Optical calculation of correlation filters for a robotic vision system
NASA Technical Reports Server (NTRS)
Knopp, Jerome
1989-01-01
A method is presented for designing optical correlation filters based on measuring three intensity patterns: the Fourier transform of a filter object, a reference wave and the interference pattern produced by the sum of the object transform and the reference. The method can produce a filter that is well matched to both the object, its transforming optical system and the spatial light modulator used in the correlator input plane. A computer simulation was presented to demonstrate the approach for the special case of a conventional binary phase-only filter. The simulation produced a workable filter with a sharp correlation peak.
Digging for Fossils in the Hertzsprung Gap
NASA Technical Reports Server (NTRS)
Ayres, Thomas R.
1999-01-01
Objective was to conduct deep (approx. 250 ks) pointings on two EUV sources, the early-F giant beta Cas and the mid-G giant mu Velorum; to obtain spectra in the range 70-300 A and to record Deep Survey light curves over the extensive duration of each observation. We have analyzed the DS lightcurve and the SW spectrum, breaking the latter lip into time slices corresponding to key phases of the observation: pre-flare, flare rise, and two segments of the flare decay.
Optical sectioning microscopes with no moving parts using a micro-stripe array light emitting diode.
Poher, V; Zhang, H X; Kennedy, G T; Griffin, C; Oddos, S; Gu, E; Elson, D S; Girkin, M; French, P M W; Dawson, M D; Neil, M A
2007-09-03
We describe an optical sectioning microscopy system with no moving parts based on a micro-structured stripe-array light emitting diode (LED). By projecting arbitrary line or grid patterns onto the object, we are able to implement a variety of optical sectioning microscopy techniques such as grid-projection structured illumination and line scanning confocal microscopy, switching from one imaging technique to another without modifying the microscope setup. The micro-structured LED and driver are detailed and depth discrimination capabilities are measured and calculated.
Wide-field imaging through scattering media by scattered light fluorescence microscopy
NASA Astrophysics Data System (ADS)
Zhou, Yulan; Li, Xun
2017-08-01
To obtain images through scattering media, scattered light fluorescence (SLF) microscopy that utilizes the optical memory effect has been developed. However, the small field of view (FOV) of SLF microscopy limits its application. In this paper, we have introduced a re-modulation method to achieve wide-field imaging through scattering media by SLF microscopy. In the re-modulation method, to raster scan the focus across the object plane, the incident wavefront is re-modulated via a spatial light modulator (SLM) in the updated phase compensation calculated using the optimized iterative algorithm. Compared with the conventional optical memory effect method, the re-modulation method can greatly increase the FOV of a SLF microscope. With the phase compensation theoretically calculated, the process of updating the phase compensation of a high speed SLM is fast. The re-modulation method does not increase the imaging time. The re-modulation method is, therefore, expected to make SLF microscopy have much wider applications in biology, medicine and physiology.
Study of a high-precision SAW-MOEMS strain sensor with laser optics
NASA Astrophysics Data System (ADS)
Liu, Xinwei; Chen, Shufen; Li, Honglang; Zou, Zhengfeng; Fu, Lei; Meng, Yanbin
2015-02-01
A novel structure design of a surface acoustic wave (SAW) micro-optic-electro-mechanical-system (MOEMS) strain sensor with a light readout unit is presented in this paper. By measuring the polarization intensity ratio of the TE/TM mode outputted from the waveguide, the strain produced from an object can be measured precisely. The basic working principle of the SAW MOEMS strain sensor is introduced and the mathematical model of the strain sensor system is established. The SAW characteristics effected by the strain sensor are mathematically deduced. The coupling coefficient between the SAW modes and light modes can be calculated based on the theory of coupling modes. The conversion coefficient of polarized light modes is obtained. Due to the restrictions of the specific parameters of the device, the level of technology and the material characteristics, the sensitivity of the strain sensor system is calculated through simulation as 0.1 μɛ, with a dynamic range of 0 ~ ±50 μɛ.
Does Calculation or Word-Problem Instruction Provide A Stronger Route to Pre-Algebraic Knowledge?
Fuchs, Lynn S.; Powell, Sarah R.; Cirino, Paul T.; Schumacher, Robin F.; Marrin, Sarah; Hamlett, Carol L.; Fuchs, Douglas; Compton, Donald L.; Changas, Paul C.
2014-01-01
The focus of this study was connections among 3 aspects of mathematical cognition at 2nd grade: calculations, word problems, and pre-algebraic knowledge. We extended the literature, which is dominated by correlational work, by examining whether intervention conducted on calculations or word problems contributes to improved performance in the other domain and whether intervention in either or both domains contributes to pre-algebraic knowledge. Participants were 1102 children in 127 2nd-grade classrooms in 25 schools. Teachers were randomly assigned to 3 conditions: calculation intervention, word-problem intervention, and business-as-usual control. Intervention, which lasted 17 weeks, was designed to provide research-based linkages between arithmetic calculations or arithmetic word problems (depending on condition) to pre-algebraic knowledge. Multilevel modeling suggested calculation intervention improved calculation but not word-problem outcomes; word-problem intervention enhanced word-problem but not calculation outcomes; and word-problem intervention provided a stronger route than calculation intervention to pre-algebraic knowledge. PMID:25541565
NASA Astrophysics Data System (ADS)
Jurdana-Šepić, R.; Poljančić Beljan, I.
Searching for T Tauri stars or related early type variables we carried out a BVRI photometric measurements of five candidates with positions within the field of the pre-main sequence object V733 Cephei (Persson's star) located in the dark cloud L1216 near to Cepheus OB3 Association: VES 946, VES 950, NSV 14333, NSV 25966 and V385 Cep. Their magnitudes are determined on the plates from Asiago Observatory historical photographic archive exposed 1971 - 1978. We provide finding charts for program stars and comparison sequence stars, magnitude estimations, magnitude mean values and BVR_cI_c light curves of program stars.
Nikolaev, V P; Katuntsev, V P
1998-01-01
Objectives of the study were comparative assessment of the risk of decompression sickness (DCS) in human subjects during shirt-sleeve simulation of extravehicular activity (EVA) following Russian and U.S. protocols, and analysis of causes of the difference between real and simulated EVA decompression safety. To this end, DCS risk during exposure to a sing-step decompression was estimated with an original method. According to the method, DCS incidence is determined by distribution of nucleation efficacy index (z) in the worst body tissues and its critical values (zm) as a function of initial nitrogen tension in these tissues and final ambient pressure post decompression. Gaussian distribution of z values was calculated basing on results of the DCS risk evaluation on the U.S. EVA protocol in an unsuited chamber test with various pre-breath procedures (Conkin et al., 1987). Half-time of nitrogen washout from the worst tissues was presumed to be 480 min. Calculated DCS risk during short-sleeve EVA simulation by the Russian and U.S. protocols with identical physical loading made up 19.2% and 23.4%, respectively. Effects of the working spacesuit pressure, spacesuit rigidity, metabolic rates during operations in EVA space suit, transcutaneous nitrogen exchange in the oxygen atmosphere of space suit, microgravity, analgesics, short compression due to spacesuit leak tests on the eye of EVA are discussed. Data of the study illustrate and advocate for high decompression safety of current Russian and U.S. EVA protocols.
USDA-ARS?s Scientific Manuscript database
Light signals regulate plant growth and development by controlling a plethora of gene expression changes. Post-transcriptional regulation, especially pre-mRNA processing, is a key modulator of gene expression; however, the molecular mechanisms linking pre-mRNA processing and light signaling are not ...
Coupling control and optimization at the Canadian Light Source
NASA Astrophysics Data System (ADS)
Wurtz, W. A.
2018-06-01
We present a detailed study using the skew quadrupoles in the Canadian Light Source storage ring lattice to control the parameters of a coupled lattice. We calculate the six-dimensional beam envelop matrix and use it to produce a variety of objective functions for optimization using the Multi-Objective Particle Swarm Optimization (MOPSO) algorithm. MOPSO produces a number of skew quadrupole configurations that we apply to the storage ring. We use the X-ray synchrotron radiation diagnostic beamline to image the beam and we make measurements of the vertical dispersion and beam lifetime. We observe satisfactory agreement between the measurements and simulations. These methods can be used to adjust phase space coupling in a rational way and have applications to fine-tuning the vertical emittance and Touschek lifetime and measuring the gas scattering lifetime.
Bar coded retroreflective target
Vann, Charles S.
2000-01-01
This small, inexpensive, non-contact laser sensor can detect the location of a retroreflective target in a relatively large volume and up to six degrees of position. The tracker's laser beam is formed into a plane of light which is swept across the space of interest. When the beam illuminates the retroreflector, some of the light returns to the tracker. The intensity, angle, and time of the return beam is measured to calculate the three dimensional location of the target. With three retroreflectors on the target, the locations of three points on the target are measured, enabling the calculation of all six degrees of target position. Until now, devices for three-dimensional tracking of objects in a large volume have been heavy, large, and very expensive. Because of the simplicity and unique characteristics of this tracker, it is capable of three-dimensional tracking of one to several objects in a large volume, yet it is compact, light-weight, and relatively inexpensive. Alternatively, a tracker produces a diverging laser beam which is directed towards a fixed position, and senses when a retroreflective target enters the fixed field of view. An optically bar coded target can be read by the tracker to provide information about the target. The target can be formed of a ball lens with a bar code on one end. As the target moves through the field, the ball lens causes the laser beam to scan across the bar code.
Vann, Charles S.
2003-09-09
This small, inexpensive, non-contact laser sensor can detect the location of a retroreflective target in a relatively large volume and up to six degrees of position. The tracker's laser beam is formed into a plane of light which is swept across the space of interest. When the beam illuminates the retroreflector, some of the light returns to the tracker. The intensity, angle, and time of the return beam is measured to calculate the three dimensional location of the target. With three retroreflectors on the target, the locations of three points on the target are measured, enabling the calculation of all six degrees of target position. Until now, devices for three-dimensional tracking of objects in a large volume have been heavy, large, and very expensive. Because of the simplicity and unique characteristics of this tracker, it is capable of three-dimensional tracking of one to several objects in a large volume, yet it is compact, light-weight, and relatively inexpensive. Alternatively, a tracker produces a diverging laser beam which is directed towards a fixed position, and senses when a retroreflective target enters the fixed field of view. An optically bar coded target can be read by the tracker to provide information about the target. The target can be formed of a ball lens with a bar code on one end. As the target moves through the field, the ball lens causes the laser beam to scan across the bar code.
Object memory and change detection: dissociation as a function of visual and conceptual similarity.
Yeh, Yei-Yu; Yang, Cheng-Ta
2008-01-01
People often fail to detect a change between two visual scenes, a phenomenon referred to as change blindness. This study investigates how a post-change object's similarity to the pre-change object influences memory of the pre-change object and affects change detection. The results of Experiment 1 showed that similarity lowered detection sensitivity but did not affect the speed of identifying the pre-change object, suggesting that similarity between the pre- and post-change objects does not degrade the pre-change representation. Identification speed for the pre-change object was faster than naming the new object regardless of detection accuracy. Similarity also decreased detection sensitivity in Experiment 2 but improved the recognition of the pre-change object under both correct detection and detection failure. The similarity effect on recognition was greatly reduced when 20% of each pre-change stimulus was masked by random dots in Experiment 3. Together the results suggest that the level of pre-change representation under detection failure is equivalent to the level under correct detection and that the pre-change representation is almost complete. Similarity lowers detection sensitivity but improves explicit access in recognition. Dissociation arises between recognition and change detection as the two judgments rely on the match-to-mismatch signal and mismatch-to-match signal, respectively.
NASA Astrophysics Data System (ADS)
Cambra-López, María; Winkel, Albert; Mosquera, Julio; Ogink, Nico W. M.; Aarnink, André J. A.
2015-06-01
The objective of this study was to compare co-located real-time light scattering devices and equivalent gravimetric samplers in poultry and pig houses for PM10 mass concentration, and to develop animal-specific calibration factors for light scattering samplers. These results will contribute to evaluate the comparability of different sampling instruments for PM10 concentrations. Paired DustTrak light scattering device (DustTrak aerosol monitor, TSI, U.S.) and PM10 gravimetric cyclone sampler were used for measuring PM10 mass concentrations during 24 h periods (from noon to noon) inside animal houses. Sampling was conducted in 32 animal houses in the Netherlands, including broilers, broiler breeders, layers in floor and in aviary system, turkeys, piglets, growing-finishing pigs in traditional and low emission housing with dry and liquid feed, and sows in individual and group housing. A total of 119 pairs of 24 h measurements (55 for poultry and 64 for pigs) were recorded and analyzed using linear regression analysis. Deviations between samplers were calculated and discussed. In poultry, cyclone sampler and DustTrak data fitted well to a linear regression, with a regression coefficient equal to 0.41, an intercept of 0.16 mg m-3 and a correlation coefficient of 0.91 (excluding turkeys). Results in turkeys showed a regression coefficient equal to 1.1 (P = 0.49), an intercept of 0.06 mg m-3 (P < 0.0001) and a correlation coefficient of 0.98. In pigs, we found a regression coefficient equal to 0.61, an intercept of 0.05 mg m-3 and a correlation coefficient of 0.84. Measured PM10 concentrations using DustTraks were clearly underestimated (approx. by a factor 2) in both poultry and pig housing systems compared with cyclone pre-separators. Absolute, relative, and random deviations increased with concentration. DustTrak light scattering devices should be self-calibrated to investigate PM10 mass concentrations accurately in animal houses. We recommend linear regression equations as animal-specific calibration factors for DustTraks instead of manufacturer calibration factors, especially in heavily dusty environments such as animal houses.
2013-01-01
Background Gallstones represent a significant burden for health care systems worldwide and are one of the most common disorders presenting to emergency room. Ultrasonography, complete blood picture test and liver function tests are procedures of choice in suspected gallstones or biliary diseases. They are the most sensitive, specific, non-invasive and inexpensive tests for the detection of gallstones. Our main objective was to evaluate the relationship of ultrasonographic findings, hemolytic indices and liver function tests with gallstones. Methodology It was a prospective study carried out in Civil Hospital Karachi (DUHS) and Liaquat National Hospital, two largest tertiary care hospitals of Karachi, Pakistan. Duration of the study was from July 2011 to October 2012. The study was carried out on diagnosed, pre-operative and symptomatic patients of cholelithiases. Exclusion criteria were patients of gallbladder and pancreatic carcinoma, emergency operations, patients having age <12 years and non-cooperative patients, who refused to give written consent for participation in the study. Total two tests were performed on each patient after diagnosis by ultrasonography. These were complete blood count and liver function tests. All the demographic data, laboratory findings and ultrasonographic features were noted in a pre-structured Performa. Sample size was calculated by using open-epidemiological sample size calculator prevalence (p) = 35%, d = 5%, and confidence interval (CI) 95% = 350. All the data was entered and analyzed through SPSS 19. Result There were 454 diagnosed and pre-operative cases of gallstones present in the study. There were 120(26.4%) males and 334(73.6%) females, with a mean age of 42.80 ± 12.26 years. Most of the suspects had multiple stones 384 (84.5%) while few had single stones 70(15.4%). Fatty liver was found to be present in 144(31.7%) patients and 92(20.2%) had hepatomegaly. Splenomegaly was present in 16(3.5%) patients. Alkaline phosphatase was elevated in 186(41.0%) patients while SGPT was found to be raised in 160(35.2%). Blood urea nitrogen was found to be elevated in 186(41%) patients and serum creatinine was elevated in 46(10.1%) patients. Conclusion In the light of findings it is recommend that all patients should go through the process of ultrasonography and all the biochemical parameters should be analyzed before surgery. PMID:23618353
Aslam, Hafiz Muhammad; Saleem, Shafaq; Edhi, Muhammad Muzzammil; Shaikh, Hiba Arshad; Khan, Jehanzeb Daniel; Hafiz, Mehak; Saleem, Maria
2013-01-01
Gallstones represent a significant burden for health care systems worldwide and are one of the most common disorders presenting to emergency room. Ultrasonography, complete blood picture test and liver function tests are procedures of choice in suspected gallstones or biliary diseases. They are the most sensitive, specific, non-invasive and inexpensive tests for the detection of gallstones. Our main objective was to evaluate the relationship of ultrasonographic findings, hemolytic indices and liver function tests with gallstones. It was a prospective study carried out in Civil Hospital Karachi (DUHS) and Liaquat National Hospital, two largest tertiary care hospitals of Karachi, Pakistan. Duration of the study was from July 2011 to October 2012. The study was carried out on diagnosed, pre-operative and symptomatic patients of cholelithiases. Exclusion criteria were patients of gallbladder and pancreatic carcinoma, emergency operations, patients having age <12 years and non-cooperative patients, who refused to give written consent for participation in the study. Total two tests were performed on each patient after diagnosis by ultrasonography. These were complete blood count and liver function tests. All the demographic data, laboratory findings and ultrasonographic features were noted in a pre-structured Performa. Sample size was calculated by using open-epidemiological sample size calculator prevalence (p) = 35%, d = 5%, and confidence interval (CI) 95% = 350. All the data was entered and analyzed through SPSS 19. There were 454 diagnosed and pre-operative cases of gallstones present in the study. There were 120(26.4%) males and 334(73.6%) females, with a mean age of 42.80 ± 12.26 years. Most of the suspects had multiple stones 384 (84.5%) while few had single stones 70(15.4%). Fatty liver was found to be present in 144(31.7%) patients and 92(20.2%) had hepatomegaly. Splenomegaly was present in 16(3.5%) patients. Alkaline phosphatase was elevated in 186(41.0%) patients while SGPT was found to be raised in 160(35.2%). Blood urea nitrogen was found to be elevated in 186(41%) patients and serum creatinine was elevated in 46(10.1%) patients. In the light of findings it is recommend that all patients should go through the process of ultrasonography and all the biochemical parameters should be analyzed before surgery.
NASA Astrophysics Data System (ADS)
Sarbadhicary, Sumit; Badenes, Carles; Chomiuk, Laura; Maldonado, Jessica; Caprioli, Damiano; Heger, Mairead; Huizenga, Daniel
2018-01-01
Our understanding of the progenitors of many stellar species, such as supernovae, massive and low-mass He-burning stars, is limited because of many poorly constrained aspects of stellar evolution theory. For my dissertation, I have focused on using Local Group galaxy surveys to constrain stellar evolution scenarios by measuring delay-time distributions (DTD). The DTD is the hypothetical occurrence rate of a stellar object per elapsed time after a brief burst of star formation. It is the measured distribution of timescales on which stars evolve, and therefore serves as a powerful observational constraint on theoretical progenitor models. The DTD can be measured from a survey of stellar objects and a set of star-formation histories of the host galaxy, and is particularly effective in the Local Group, where high-quality star-formation histories are available from resolved stellar populations. I am currently calculating a SN DTD with supernova remnants (SNRs) in order to provide the strongest constraints on the progenitors of thermonuclear and core-collapse supernovae. However, most SNRs do not have reliable age measurements and their evolution depends on the ambient environment. For this reason, I wrote a radio light curve model of an SNR population to extract the visibility times and rates of supernovae - crucial ingredients for the DTD - from an SNR survey. The model uses observational constraints on the local environments from multi-wavelength surveys, accounts for missing SNRs and employs the latest models of shock-driven particle acceleration. The final calculation of the SN DTD in the Local Group is awaiting completion of a systematic SNR catalog from deep radio-continuum images, now in preparation by a group led by Dr. Laura Chomiuk. I have also calculated DTDs for the LMC population of RR Lyrae and Cepheid variables, which serve as important distance calibrators and stellar population tracers. We find that Cepheids can have delay-times between 10 Myrs - 1 Gyr, while RR Lyrae can have delay-times < 10 Gyrs. These observations cannot be explained by models using mass and metallicity alone. In future projects, I will apply the DTD technique to constrain the supergiant and pre-supernova evolutionary models.
Front panel engineering with CAD simulation tool
NASA Astrophysics Data System (ADS)
Delacour, Jacques; Ungar, Serge; Mathieu, Gilles; Hasna, Guenther; Martinez, Pascal; Roche, Jean-Christophe
1999-04-01
THe progress made recently in display technology covers many fields of application. The specification of radiance, colorimetry and lighting efficiency creates some new challenges for designers. Photometric design is limited by the capability of correctly predicting the result of a lighting system, to save on the costs and time taken to build multiple prototypes or bread board benches. The second step of the research carried out by company OPTIS is to propose an optimization method to be applied to the lighting system, developed in the software SPEOS. The main features of the tool requires include the CAD interface, to enable fast and efficient transfer between mechanical and light design software, the source modeling, the light transfer model and an optimization tool. The CAD interface is mainly a prototype of transfer, which is not the subjects here. Photometric simulation is efficiently achieved by using the measured source encoding and a simulation by the Monte Carlo method. Today, the advantages and the limitations of the Monte Carlo method are well known. The noise reduction requires a long calculation time, which increases with the complexity of the display panel. A successful optimization is difficult to achieve, due to the long calculation time required for each optimization pass including a Monte Carlo simulation. The problem was initially defined as an engineering method of study. The experience shows that good understanding and mastering of the phenomenon of light transfer is limited by the complexity of non sequential propagation. The engineer must call for the help of a simulation and optimization tool. The main point needed to be able to perform an efficient optimization is a quick method for simulating light transfer. Much work has been done in this area and some interesting results can be observed. It must be said that the Monte Carlo method wastes time calculating some results and information which are not required for the needs of the simulation. Low efficiency transfer system cost a lot of lost time. More generally, the light transfer simulation can be treated efficiently when the integrated result is composed of elementary sub results that include quick analytical calculated intersections. The first axis of research appear. The quick integration research and the quick calculation of geometric intersections. The first axis of research brings some general solutions also valid for multi-reflection systems. The second axis requires some deep thinking on the intersection calculation. An interesting way is the subdivision of space in VOXELS. This is an adapted method of 3D division of space according to the objects and their location. An experimental software has been developed to provide a validation of the method. The gain is particularly high in complex systems. An important reduction in the calculation time has been achieved.
Ganandran, G S B; Mahlia, T M I; Ong, Hwai Chyuan; Rismanchi, B; Chong, W T
2014-01-01
This paper reports the result of an investigation on the potential energy saving of the lighting systems at selected buildings of the Universiti Tenaga Nasional. The scope of this project includes evaluation of the lighting system in the Library, Admin Building, College of Engineering, College of Information Technology, Apartments, and COE Food court of the university. The main objectives of this project are to design the proper retrofit scenario and to calculate the potential electricity saving, the payback period, and the potential environmental benefits. In this survey the policy for retrofitting the old lighting system with the new energy saving LEDs starts with 10% for the first year and continues constantly for 10 years until all the lighting systems have been replaced. The result of the life cycle analysis reveals that after four years, the selected buildings will bring profit for the investment.
Ganandran, G. S. B.; Mahlia, T. M. I.; Ong, Hwai Chyuan; Rismanchi, B.; Chong, W. T.
2014-01-01
This paper reports the result of an investigation on the potential energy saving of the lighting systems at selected buildings of the Universiti Tenaga Nasional. The scope of this project includes evaluation of the lighting system in the Library, Admin Building, College of Engineering, College of Information Technology, Apartments, and COE Food court of the university. The main objectives of this project are to design the proper retrofit scenario and to calculate the potential electricity saving, the payback period, and the potential environmental benefits. In this survey the policy for retrofitting the old lighting system with the new energy saving LEDs starts with 10% for the first year and continues constantly for 10 years until all the lighting systems have been replaced. The result of the life cycle analysis reveals that after four years, the selected buildings will bring profit for the investment. PMID:25133258
Fuel Optimal, Finite Thrust Guidance Methods to Circumnavigate with Lighting Constraints
NASA Astrophysics Data System (ADS)
Prince, E. R.; Carr, R. W.; Cobb, R. G.
This paper details improvements made to the authors' most recent work to find fuel optimal, finite-thrust guidance to inject an inspector satellite into a prescribed natural motion circumnavigation (NMC) orbit about a resident space object (RSO) in geosynchronous orbit (GEO). Better initial guess methodologies are developed for the low-fidelity model nonlinear programming problem (NLP) solver to include using Clohessy- Wiltshire (CW) targeting, a modified particle swarm optimization (PSO), and MATLAB's genetic algorithm (GA). These initial guess solutions may then be fed into the NLP solver as an initial guess, where a different NLP solver, IPOPT, is used. Celestial lighting constraints are taken into account in addition to the sunlight constraint, ensuring that the resulting NMC also adheres to Moon and Earth lighting constraints. The guidance is initially calculated given a fixed final time, and then solutions are also calculated for fixed final times before and after the original fixed final time, allowing mission planners to choose the lowest-cost solution in the resulting range which satisfies all constraints. The developed algorithms provide computationally fast and highly reliable methods for determining fuel optimal guidance for NMC injections while also adhering to multiple lighting constraints.
CAMSS: A spectroscopic survey of meteoroid elemental abundances
NASA Astrophysics Data System (ADS)
Jenniskens, P.; Gural, P.; Berdeu, A.
2014-07-01
The main element abundances (Mg, Fe, Na, ...) of some Near Earth Objects can be measured by meteor spectroscopy. The Cameras for All-sky Meteor Surveillance (CAMS) Spectrograph project aims to scale up meteor spectroscopy in the same way as CAMS scaled up the measurement of precise meteoroid trajectories from multi-station video observations. Spectra are recorded with sixteen low-light video cameras, each equipped with a high 1379 lines/mm objective transmission grating. The cameras are operated in survey mode and have recorded spectra in the San Francisco Bay Area every clear night since March 12, 2013. An interactive software tool is being developed to calibrate the wavelength alignments projected on the focal plane and extract the meteor spectra. Because the meteoroid trajectory and pre-atmospheric orbit are also independently measured, the absolute abundances of elements in the meteoroid plasma can be calculated as a function of altitude, while the orbital information can tie the meteoroid back to its parent object. % 2007AdSpR..39..538A Berezhnoy, A. A., Borovička, J. 2012, ACM 2012, Abstract 6142 1993A&A...279..627B 1994A&AS..103...83B 2005Icar..174...15B 2011pimo.conf...28G Gural, P. S. 2012, M&PS, 47, 1405 1997ApJ...479..441J 2007AdSpR..39..491J 2011Icar..216...40J Gomez, N., Madiedo, J. M., & Trigo-Rodriguez, J. M. 2013, 44th LPSC, Abstract 1239 2007AdSpR..39..513K 2004AJ....128.2564M 2007AdSpR..39..583R 2007AdSpR..39..517T 2011A&A...526A.126W
Learning of perceptual grouping for object segmentation on RGB-D data☆
Richtsfeld, Andreas; Mörwald, Thomas; Prankl, Johann; Zillich, Michael; Vincze, Markus
2014-01-01
Object segmentation of unknown objects with arbitrary shape in cluttered scenes is an ambitious goal in computer vision and became a great impulse with the introduction of cheap and powerful RGB-D sensors. We introduce a framework for segmenting RGB-D images where data is processed in a hierarchical fashion. After pre-clustering on pixel level parametric surface patches are estimated. Different relations between patch-pairs are calculated, which we derive from perceptual grouping principles, and support vector machine classification is employed to learn Perceptual Grouping. Finally, we show that object hypotheses generation with Graph-Cut finds a globally optimal solution and prevents wrong grouping. Our framework is able to segment objects, even if they are stacked or jumbled in cluttered scenes. We also tackle the problem of segmenting objects when they are partially occluded. The work is evaluated on publicly available object segmentation databases and also compared with state-of-the-art work of object segmentation. PMID:24478571
Digital holographic tomography based on spectral interferometry.
Yu, Lingfeng; Chen, Zhongping
2007-10-15
A digital holographic tomography system has been developed with the use of an inexpensive broadband light source and a fiber-based spectral interferometer. Multiple synthesized holograms (or object wave fields) of different wavelengths are obtained by transversely scanning a probe beam. The acquisition speed is improved compared with conventional wavelength-scanning digital holographic systems. The optical field of a volume around the object location is calculated by numerical diffraction from each synthesized hologram, and all such field volumes are numerically superposed to create the three-dimensional tomographic image. Experiments were performed to demonstrate the idea.
Deng, Mingdan; Qian, Hongmei; Chen, Lili; Sun, Bo; Chang, Jiaqi; Miao, Huiying; Cai, Congxi; Wang, Qiaomei
2017-05-01
The effects of pre-harvest red light irradiation on main healthy phytochemicals as well as antioxidant activity of Chinese kale sprouts during postharvest storage were investigated. 6-day-old sprouts were treated by red light for 24h before harvest and sampled for further analysis of nutritional quality on the first, second and third day after harvest. The results indicated that red light exposure notably postponed the degradation of aliphatic, indole, and total glucosinolates during postharvest storage. The vitamin C level was remarkably higher in red light treated sprouts on the first and second day after harvest when compared with the control. In addition, red light treatment also enhanced the accumulation of total phenolics and maintained higher level of antioxidant activity than the control. All above results suggested that pre-harvest red light treatment might provide a new strategy to maintain the nutritive value of Chinese kale sprouts during postharvest storage. Copyright © 2016 Elsevier Ltd. All rights reserved.
Creating Affording Situations: Coaching through Animate Objects.
Baber, Chris; Khattab, Ahmad; Russell, Martin; Hermsdörfer, Joachim; Wing, Alan
2017-10-11
We explore the ways in which animate objects can be used to cue actions as part of coaching in Activities of Daily Living (ADL). In this case, changing the appearance or behavior of a physical object is intended to cue actions which are appropriate for a given context. The context is defined by the intention of the users, the state of the objects and the tasks for which these objects can be used. We present initial design prototypes and simple user trials which explore the impact of different cues on activity. It is shown that raising the handle of a jug, for example, not only cues the act of picking up the jug but also encourages use of the hand adjacent to the handle; that combinations of lights (on the objects) and auditory cues influence activity through reducing uncertainty; and that cueing can challenge pre-learned action sequences. We interpret these results in terms of the idea that the animate objects can be used to create affording situations, and discuss implications of this work to support relearning of ADL following brain damage or injury, such as might arise following a stroke.
Slit Function Measurement of An Imaging Spectrograph Using Fourier Transform Techniques
NASA Technical Reports Server (NTRS)
Park, Hongwoo; Swimyard, Bruce; Jakobsen, Peter; Moseley, Harvey; Greenhouse, Matthew
2004-01-01
Knowledge of a spectrograph slit function is necessary to interpret the unresolved lines in an observed spectrum. A theoretical slit function can be calculated from the sizes of the entrance slit, the detector aperture when it functions as an exit slit, the dispersion characteristic of the disperser, and the point spread function of the spectrograph. A measured slit function is preferred to the theoretical one for the correct interpretation of the spectral data. In a scanning spectrometer with a single exit slit, the slit function is easily measured. In a fixed grating/or disperser spectrograph, illuminating the entrance slit with a near monochromatic light from a pre-monochrmator or a tunable laser and varying the wavelength of the incident light can measure the slit function. Even though the latter technique had been used successfully for the slit function measurements, it had been very laborious and it would be prohibitive to an imaging spectrograph or a multi-object spectrograph that has a large field of view. We explore an alternative technique that is manageable for the measurements. In the proposed technique, the imaging spectrograph is used as a detector of a Fourier transform spectrometer. This method can be applied not only to an IR spectrograph but also has a potential to a visible/UV spectrograph including a wedge filter spectrograph. This technique will require a blackbody source of known temperature and a bolometer to characterize the interferometer part of the Fourier Transform spectrometer. This pa?er will describe the alternative slit function measurement technique using a Fourier transform spectrometer.
NASA Astrophysics Data System (ADS)
Perrier, C.; Breysacher, J.; Rauw, G.
2009-09-01
Aims: We present a technique to determine the orbital and physical parameters of eclipsing eccentric Wolf-Rayet + O-star binaries, where one eclipse is produced by the absorption of the O-star light by the stellar wind of the W-R star. Methods: Our method is based on the use of the empirical moments of the light curve that are integral transforms evaluated from the observed light curves. The optical depth along the line of sight and the limb darkening of the W-R star are modelled by simple mathematical functions, and we derive analytical expressions for the moments of the light curve as a function of the orbital parameters and the key parameters of the transparency and limb-darkening functions. These analytical expressions are then inverted in order to derive the values of the orbital inclination, the stellar radii, the fractional luminosities, and the parameters of the wind transparency and limb-darkening laws. Results: The method is applied to the SMC W-R eclipsing binary HD 5980, a remarkable object that underwent an LBV-like event in August 1994. The analysis refers to the pre-outburst observational data. A synthetic light curve based on the elements derived for the system allows a quality assessment of the results obtained.
NASA Technical Reports Server (NTRS)
Buck, Gregory M. (Inventor)
1989-01-01
A thermal imaging system provides quantitative temperature information and is particularly useful in hypersonic wind tunnel applications. An object to be measured is prepared by coating with a two-color, ultraviolet-activated, thermographic phosphor. The colors emitted by the phosphor are detected by a conventional color video camera. A phosphor emitting blue and green light with a ratio that varies depending on temperature is used so that the intensity of light in the blue and green wavelengths detected by the blue and green tubes in the video camera can be compared. Signals representing the intensity of blue and green light at points on the surface of a model in a hypersonic wind tunnel are used to calculate a ratio of blue to green light intensity which provides quantitative temperature information for the surface of the model.
Automated measurement of spatial preference in the open field test with transmitted lighting.
Kulikov, Alexander V; Tikhonova, Maria A; Kulikov, Victor A
2008-05-30
New modification of the open field was designed to improve automation of the test. The main innovations were: (1) transmitted lighting and (2) estimation of probability to find pixels associated with an animal in the selected region of arena as an objective index of spatial preference. Transmitted (inverted) lighting significantly ameliorated the contrast between an animal and arena and allowed to track white animals with similar efficacy as colored ones. Probability as a measure of preference of selected region was mathematically proved and experimentally verified. A good correlation between probability and classic indices of spatial preference (number of region entries and time spent therein) was shown. The algorithm of calculation of probability to find pixels associated with an animal in the selected region was implemented in the EthoStudio software. Significant interstrain differences in locomotion and the central zone preference (index of anxiety) were shown using the inverted lighting and the EthoStudio software in mice of six inbred strains. The effects of arena shape (circle or square) and a novel object presence in the center of arena on the open field behavior in mice were studied.
NASA Astrophysics Data System (ADS)
Liu, Shasha; Zhao, Xiuming; Li, Yuanzuo; Zhao, Xiaohong; Chen, Maodu
2009-06-01
Density functional theory (DFT) and time-dependent DFT calculations have been performed to investigate the Raman scattering spectra of metal-molecule complex and metal-molecule-metal junction architectures interconnected with 4-aminothiophenol (PATP) molecule. The simulated profiles of normal Raman scattering (NRS) spectra for the two complexes (Ag2-PATP and PATP-Au2) and the two junctions (Ag2-PATP-Au2 and Au2-PATP-Ag2) are similar to each other, but exhibit obviously different Raman intensities. Due to the lager static polarizabilities of the two junctions, which directly influence the ground state chemical enhancement in NRS spectra, the calculated normal Raman intensities of them are stronger than those of two complexes by the factor of 102. We calculate preresonance Raman scattering (RRS) spectra with incident light at 1064 nm, which is much lower than the S1 electronic transition energy of complexes and junctions. Ag2-PATP-Au2 and Au2-PATP-Ag2 junctions yield higher Raman intensities than those of Ag2-PATP and PATP-Au2 complexes, especially for b2 modes. This effect is mainly attributed to charge transfer (CT) between the metal gap and the PAPT molecule which results in the occurrence of CT resonance enhancement. The calculated pre-RRS spectra strongly depend on the electronic transition state produced by new structures. With excitation at 514.5 nm, the calculated pre-RRS spectra of two complexes and two junctions are stronger than those of with excitation at 1064 nm. A charge difference densities methodology has been used to visually describe chemical enhancement mechanism of RRS spectrum. This methodology aims at visualizing intermolecular CT which provides direct evidence of the Herzberg-Teller mechanism.
Fuchs, Lynn S.; Compton, Donald L.; Fuchs, Douglas; Powell, Sarah R.; Schumacher, Robin F.; Hamlett, Carol L.; Vernier, Emily; Namkung, Jessica M.; Vukovic, Rose K.
2012-01-01
The purpose of this study was to investigate the contributions of domain-general cognitive resources and different forms of arithmetic development to individual differences in pre-algebraic knowledge. Children (n=279; mean age=7.59 yrs) were assessed on 7 domain-general cognitive resources as well as arithmetic calculations and word problems at start of 2nd grade and on calculations, word problems, and pre-algebraic knowledge at end of 3rd grade. Multilevel path analysis, controlling for instructional effects associated with the sequence of classrooms in which students were nested across grades 2–3, indicated arithmetic calculations and word problems are foundational to pre-algebraic knowledge. Also, results revealed direct contributions of nonverbal reasoning and oral language to pre-algebraic knowledge, beyond indirect effects that are mediated via arithmetic calculations and word problems. By contrast, attentive behavior, phonological processing, and processing speed contributed to pre-algebraic knowledge only indirectly via arithmetic calculations and word problems. PMID:22409764
Lamont, Scott; Brunero, Scott
2018-05-19
Workplace violence prevalence has attracted significant attention within the international nursing literature. Little attention to non-mental health settings and a lack of evaluation rigor have been identified within review literature. To examine the effects of a workplace violence training program in relation to risk assessment and management practices, de-escalation skills, breakaway techniques, and confidence levels, within an acute hospital setting. A quasi-experimental study of nurses using pretest-posttest measurements of educational objectives and confidence levels, with two week follow-up. A 440 bed metropolitan tertiary referral hospital in Sydney, Australia. Nurses working in specialties identified as a 'high risk' for violence. A pre-post-test design was used with participants attending a one day workshop. The workshop evaluation comprised the use of two validated questionnaires: the Continuing Professional Development Reaction questionnaire, and the Confidence in Coping with Patient Aggression Instrument. Descriptive and inferential statistics were calculated. The paired t-test was used to assess the statistical significance of changes in the clinical behaviour intention and confidence scores from pre- to post-intervention. Cohen's d effect sizes were calculated to determine the extent of the significant results. Seventy-eight participants completed both pre- and post-workshop evaluation questionnaires. Statistically significant increases in behaviour intention scores were found in fourteen of the fifteen constructs relating to the three broad workshop objectives, and confidence ratings, with medium to large effect sizes observed in some constructs. A significant increase in overall confidence in coping with patient aggression was also found post-test with large effect size. Positive results were observed from the workplace violence training. Training needs to be complimented by a multi-faceted organisational approach which includes governance, quality and review processes. Copyright © 2018 Elsevier Ltd. All rights reserved.
Han, Dong; Ma, Guangming; Wei, Lequn; Ren, Chenglong; Zhou, Jieli; Shen, Chen
2017-01-01
Objective: To investigate the value of using the quantitative parameters from only the pre-contrast dual-energy spectral CT imaging for distinguishing between parapelvic cyst and hydronephrosis with non-calculous (HNC). Methods: This retrospective study was approved by the institutional review board. 28 patients with parapelvic cyst and 24 patients with HNC who underwent standard pre-contrast and multiphase contrast-enhanced dual-energy spectral CT imaging were retrospectively identified. The parapelvic cyst and HNC were identified using the contrast-enhanced scans, and their CT number in the 70-keV monochromatic images, effective atomic number (Zeff), iodine concentration (IC) and water concentration in the pre-contrast images were measured. The slope of the spectral curve (λ) was calculated. The difference in the measurements between parapelvic cyst and HNC was statistically analyzed using SPSS® v. 19.0 (IBM Corp., New York, NY; formerly SPSS Inc., Chicago, IL) statistical software. Receiver-operating characteristic analysis was performed to assess the diagnostic performance. Results: The CT numbers in the 70-keV images, Zeff and IC values were statistically different between parapelvic cyst and HNC (all p < 0.05). The sensitivity, specificity and accuracy of these parameters for distinguishing between parapelvic cyst and HNC were 89.2%, 73.3% and 82.1%; 86.5%, 43.3% and 67.2%; 91.9%, 40.0% and 68.7%; and 64.9%, 73.3% and 83.6%, respectively, and the combined specificity was 92.9%. There was no statistical difference in λ between the two groups (p > 0.05). Conclusion: The quantitative parameters obtained in the pre-contrast dual-energy spectral CT imaging may be used to differentiate between parapelvic cyst and HNC. Advances in knowledge: The pre-contrast dual-energy spectral CT scans may be used to screen parapelvic cysts for patients who are asymptomatic, thereby avoiding contrast-enhanced CT or CT urography examination for these patients to reduce ionizing radiation dose and contrast dose. PMID:28281789
Crow, W T; Chen, F; Reichle, R H; Liu, Q
2017-06-16
Recent advances in remote sensing and land data assimilation purport to improve the quality of antecedent soil moisture information available for operational hydrologic forecasting. We objectively validate this claim by calculating the strength of the relationship between storm-scale runoff ratio (i.e., total stream flow divided by total rainfall accumulation in depth units) and pre-storm surface soil moisture estimates from a range of surface soil moisture data products. Results demonstrate that both satellite-based, L-band microwave radiometry and the application of land data assimilation techniques have significantly improved the utility of surface soil moisture data sets for forecasting stream flow response to future rainfall events.
Crow, W.T.; Chen, F.; Reichle, R.H.; Liu, Q.
2018-01-01
Recent advances in remote sensing and land data assimilation purport to improve the quality of antecedent soil moisture information available for operational hydrologic forecasting. We objectively validate this claim by calculating the strength of the relationship between storm-scale runoff ratio (i.e., total stream flow divided by total rainfall accumulation in depth units) and pre-storm surface soil moisture estimates from a range of surface soil moisture data products. Results demonstrate that both satellite-based, L-band microwave radiometry and the application of land data assimilation techniques have significantly improved the utility of surface soil moisture data sets for forecasting stream flow response to future rainfall events. PMID:29657342
Gay, Caryl L; Richoux, Sarah E; Beebe, Kathleen R; Lee, Kathryn A
2017-06-01
Poor sleep during pregnancy has been associated with poorer birth outcomes. High body mass index (BMI) is often associated with poor sleep, but little is known about the relationship between gestational weight gain and sleep in late pregnancy. The purpose of this study was to evaluate the relationships of both gestational weight gain and pre-pregnancy BMI to objective and subjective measures of sleep during late pregnancy. Pregnant women (n=128) were recruited from prenatal clinics and childbirth classes primarily serving low-income women. Their sleep (disruption and duration) was objectively assessed in their last month of pregnancy with 72 hours of wrist actigraphy monitoring. Their perceived sleep quality was assessed with the Pittsburgh Sleep Quality Index. Pre-pregnancy and late pregnancy height and weight were assessed by self-report and used to calculate BMI and gestational weight gain, which were then grouped into standardized categories. Mean Pittsburgh Sleep Quality Index score was 6.8 ± 3.1 (range 2-16). Sixty percent had excess gestational weight gain and it was associated with poorer perceived sleep quality, but was unrelated to objective measures of sleep duration and disruption. Pre-pregnancy BMI was unrelated to all sleep parameters. However, analyses of the interaction of pre-pregnancy BMI and gestational weight gain indicated that excess weight gain was associated with shorter sleep duration and more sleep disruption, but only among women who were overweight before pregnancy. Pregnancy is an opportunity to promote long-term women's health with a better understanding of the relationship between weight management and healthy sleep habits. © 2017 Wiley Periodicals, Inc.
Colour change in cyanosis and the confusions of congenital colour vision deficient observers.
McNamara, Renae; Taylor, Clair M; McKenzie, David K; Coroneo, Minas T; Dain, Stephen J
2010-09-01
Visual recognition of cyanosis is an important clinical activity. While pulse oximetry is almost universal in the hospital environment, there are circumstances where it is not available or may be unreliable. Cyanosis recognition is affected by lighting colour. In addition, there is, mainly anecdotal, evidence that people with greater colour vision deficiencies (CVDs) have particular difficulty and there is no effective lighting strategy to assist in the observation. The change of blood colour with oxygenation has been shown to lie close to the direction of colour confusions made by congenital red-green dichromats. The important sites of observation are lips, nail beds and palm creases. 10 subjects who were known to be chronically hypoxaemic were recruited from the chronic respiratory program. Their blood oxygen saturation (SpO(2)) varied from 84% to 96% pre-exercise, and 61-84% post-exercise. Ten normal subjects were recruited whose SpO(2) was 99% or 100%. The spectral radiances of lips, nail beds and palm creases were measured using a telespectroradiometer and compared with the spectral radiances of a white tile of known spectral reflectances measured in the same location. This is a non-contact method of measurement, avoiding the blanching caused by pressure of contact methods. The spectral reflectances were calculated, and the chromaticities calculated for a Planckian radiator T = 4000K. Measurements on lips yielded the most consistent results. The colour changes pre- and post-exercise and compared with normal colour lie generally along a deutan confusion line. These results show the direction of the colour change and confirm the, previously anecdotal, difficulties in detecting cyanosis by observers with CVDs. © 2010 The Authors, Ophthalmic and Physiological Optics © 2010 The College of Optometrists.
Estimating learning outcomes from pre- and posttest student self-assessments: a longitudinal study.
Schiekirka, Sarah; Reinhardt, Deborah; Beißbarth, Tim; Anders, Sven; Pukrop, Tobias; Raupach, Tobias
2013-03-01
Learning outcome is an important measure for overall teaching quality and should be addressed by comprehensive evaluation tools. The authors evaluated the validity of a novel evaluation tool based on student self-assessments, which may help identify specific strengths and weaknesses of a particular course. In 2011, the authors asked 145 fourth-year students at Göttingen Medical School to self-assess their knowledge on 33 specific learning objectives in a pretest and posttest as part of a cardiorespiratory module. The authors compared performance gain calculated from self-assessments with performance gain derived from formative examinations that were closely matched to these 33 learning objectives. Eighty-three students (57.2%) completed the assessment. There was good agreement between performance gain derived from subjective data and performance gain derived from objective examinations (Pearson r=0.78; P<.0001) on the group level. The association between the two measures was much weaker when data were analyzed on the individual level. Further analysis determined a quality cutoff for performance gain derived from aggregated student self-assessments. When using this cutoff, the evaluation tool was highly sensitive in identifying specific learning objectives with favorable or suboptimal objective performance gains. The tool is easy to implement, takes initial performance levels into account, and does not require extensive pre-post testing. By providing valid estimates of actual performance gain obtained during a teaching module, it may assist medical teachers in identifying strengths and weaknesses of a particular course on the level of specific learning objectives.
A Serum miR Signature Specific to Low-Risk Prostate Cancer
2017-09-01
useful pre-treatment risk calculators that use clinical parameters (age, biopsy grade, PSA ). These calculators accurately identify high-risk patients...aggressive disease. There are several useful pre-treatment risk calculators that use clinical parameters (age, biopsy grade, PSA ). These calculators
LIGHT EXPOSURE AMONG ADOLESCENTS WITH DELAYED SLEEP PHASE DISORDER: A PROSPECTIVE COHORT STUDY
Auger, R. Robert; Burgess, Helen J.; Dierkhising, Ross A.; Sharma, Ruchi G.; Slocumb, Nancy L.
2012-01-01
Our study objective was to compare light exposure and sleep parameters between adolescents with delayed sleep phase disorder (n=16, 15.3 ± 1.8 years) and unaffected controls (n=22, 13.7 ± 2.4 years) using a prospective cohort design. Participants wore wrist actigraphs with photosensors for 14 days. Mean hourly lux levels from 20:00-05:00 h and 05:00-14:00 h were examined, in addition to the 9-hour intervals prior to sleep onset and after sleep offset. Sleep parameters were compared separately, and were also included as covariates within models that analyzed associations with specified light intervals. Additional covariates included group and school night status. Adolescent subjects with delayed sleep phase disorder received more evening (p<0.02, 22:00-02:00 h) and less morning light (p<0.05, 08:00-09:00 h and 10:00-12:00 h) than controls, but had less pre-sleep exposure with adjustments for the time of sleep onset (p<0.03, fifth-seventh hours prior to onset hour). No differences were identified with respect to the sleep offset interval. Increased total sleep time and later sleep offset times were associated with decreased evening (p<0.001 and p=0.02, respectively) and morning (p=0.01 and p<0.001, respectively) exposure, and later sleep onset times were associated with increased evening exposure (p<0.001). Increased total sleep time also correlated with increased exposure during the 9 hours before sleep-onset (p=0.01), and a later sleep onset time corresponded with decreased exposure during the same interval (p<0.001). Outcomes persisted regardless of school night status. In conclusion, light exposure interpretation requires adjustments for sleep timing among adolescents with delayed sleep phase disorder. Pre- and post-sleep exposure do not appear to contribute directly to phase delays. Sensitivity to morning light may be reduced among adolescents with delayed sleep phase disorder. PMID:22080736
Use of pre-pulse in laser spot welding of materials with high optical reflection
NASA Astrophysics Data System (ADS)
Mys, Ihor; Geiger, Manfred
2003-11-01
Laser micro welding has become a standard manufacturing technique, particularly in industry sectors, such as automotive and aerospace electronics or medical devices, where the requirements for strength, miniaturization and temperature resistance are constantly rising. So far the use of laser micro welding is limited due to the fluctuation of the quality of the welded joints, because the welding results for material with high optical reflection and thermal conductivity, such as copper and copper alloys, depend very strongly on the condition of the material surface. This paper presents investigations on the use of a laser pre-pulse in spot welding of electronic materials with Nd:YAG laser. In order to achieve reproducible joining results two strategies are followed-up. The first one utilizes a reflection-based process control for measuring the reflection during the short pre-pulse. The intensity of the reflected light is used to calculate an appropriated welding pulse power, which corresponds to the measured relative absorption. Adjustment of laser parameters according to the condition of the surface is done in real time before laser main pulse. A second possibility for the stabilization of copper welding is the employment of a short and powerful laser pre-pulse before laser main pulse. This pre-pulse affects the workpiece surface and creates more reproducible absorption conditions for the main pulse, independent from the initial situation on material surface.
Clemes, Stacy A; O'Connell, Sophie E; Edwardson, Charlotte L
2014-03-01
To examine objectively determined sedentary behavior and physical activity (PA) during and outside working hours in full-time office workers. A total of 170 participants wore an ActiGraph GT1M accelerometer for 7 days. Time spent sedentary (<100 counts/min), in light-intensity PA (100 to 1951 counts/min), and moderate-to-vigorous PA (≥1952 counts/min) was calculated for workdays (including working hours and nonworking hours) and nonworkdays. Participants accumulated significantly higher levels of sedentary behavior (68% vs 60%) and lower levels of light-intensity activity (28% vs 36%) on workdays in comparison with nonworkdays. Up to 71% of working hours were spent sedentary. Individuals who were most sedentary at work were also more sedentary outside work. Those who are most sedentary at work do not compensate by increasing their PA or reducing their sedentary time outside work. Occupational interventions should address workplace and leisure-time sedentary behavior.
DOT National Transportation Integrated Search
2013-04-30
This report discusses light-vehicle crash countermeasure profiles and functions for five target pre-crash scenario groups based on vehicle-to-vehicle (V2V) communications. Target pre-crash scenario groups include rear-end, lane change, opposite direc...
The Making of a Pre-Planetary Nebula
NASA Astrophysics Data System (ADS)
Kohler, Susanna
2017-07-01
The gas expelled by dying stars gets twisted into intricate shapes and patterns as nebulae form. Now a team of researchers might have some answers about how this happens.Whats a Pre-Planetary Nebula?This H-R diagram for the globular cluster M5 shows where AGB stars lie: they are represented by blue markers here. The AGB is one of the final stages in a low- to intermediate-mass stars lifetime. [Lithopsian]When a low- to intermediate-mass star approaches the end of its lifetime, it moves onto the Asymptotic Giant Branch (AGB) in the Herzsprung-Russell diagram. As the star exhausts its fuel here, it shrugs off its outer layers. These layers of gas then encase the stars core, which is not yet hot enough to ionize the gas and cause it to glow.Instead, during this time the gas is relatively cool and dark, faintly reflecting light from the star and emitting only very dim infrared emission of its own. At this stage, the gas represents a pre-planetary nebula. Only later when the stellar core contracts enough to heat up and emit ionizing radiation does the nebula begin to properly glow, at which point it qualifies as a full planetary nebula.Images of OH231 in optical light (top) and 12CO (bottom) taken from the literature. [See Balick et al. 2017 for full credit]Unexpected ShapesPre-planetary nebulae are a very short-lived evolutionary stage, so weve observed only a few hundred of them which has left many unanswered questions about these objects.One particular mystery is that of their shapes: if these nebulae are formed by stars expelling their outer layers, we would naively expect them to be simple spherical shells and yet we observe pre-planetary nebulae to have intricate shapes and patterns. How does the star create these asymmetric shapes? A team of scientists led by Bruce Balick (University of Washington, Seattle) has now used simulations to address this question.Injecting MassBalick and collaborators use 3D hydrodynamic simulations to model one particular pre-planetary nebula, OH231, which lies 4,200 light-years away and is about 1.4 light-years long. This is a well studied nebula, so the team had many observations that their model needed to successfully replicate: the nebulas shapes, dimensions, overall geometry, locations of shocks, timescales, and even velocity gradients are known.The authors model included mass injection from the central source into the ambient gas in three different ways:clumps: spherical knots injected all at once,cylindrical jets: thin outflows with parallel streamlines, andsprays: conical outflows with diverging streamlines.Explanation from a Champagne BottlePanel A: best-fitting simulations of OH231 200, 400, and 800 yr after the clump and spray are launched. Panel B: example from the same family of solutions, in which the mass is reduced by a factor of 10. Click for a closer look. [Balick et al. 2017]Balick and collaborators found that by injecting the mass in these three ways with a specific order and spacing, they were able to find a family of solutions that very well replicated observations of OH231. In the best-fitting model, combinations of pairs of clumps are embedded within sprays of brief duration and launched into static ancient AGB winds. The authors compare the setup to the ejection of the cork and the spray of high-pressure fluid when a bottle of champagne is opened.These simulations successfully map out all but perhaps the first century of the nebulas evolution and give us some of the best insight yet into how these short-lived objects are formed. The authors are now working to reproduce these simulations for other pre-planetary nebulae, with the goal of piecing together common attributes of their ejection histories.CitationBruce Balick et al 2017 ApJ 843 108. doi:10.3847/1538-4357/aa77f0
NASA Astrophysics Data System (ADS)
Zhu, Jing; Bao, Xiaoqing; Zhang, Mei-Jue
2005-07-01
Objective: To research epidermal cellular vegetal cycle and the difference of DNA content between pre and post Intravascular Low Level Laser Irradiation treatment of psoriasis. Method: 15 patients suffered from psoriasis were treated by intravascular low level laser irradiation (output power: 4-5mw, 1 hour per day, a course of treatment is 10 days). We checked the different DNA content of epidermal cell between pre and post treatment of psoriasis and 8 natural human. Then the percentage of each phase among the whole cellular cycle was calculated and the statistical analysis was made. Results: The mean value of G1/S phase is obviously down while G2+M phase increased obviously. T test P<0.05.The related statistical analysis showed significant difference between pre and post treatments. Conclusions: The Intravascular Low Level Laser Irradiation (ILLLI) in treatment of psoriasis is effective according to the research of epidermal cellular vegetal cycle and the difference DNA content of Intravascular Low Level Laser Irradiation between pre and post treatment of psoriasis
Full color natural light holographic camera.
Kim, Myung K
2013-04-22
Full-color, three-dimensional images of objects under incoherent illumination are obtained by a digital holography technique. Based on self-interference of two beam-split copies of the object's optical field with differential curvatures, the apparatus consists of a beam-splitter, a few mirrors and lenses, a piezo-actuator, and a color camera. No lasers or other special illuminations are used for recording or reconstruction. Color holographic images of daylight-illuminated outdoor scenes and a halogen lamp-illuminated toy figure are obtained. From a recorded hologram, images can be calculated, or numerically focused, at any distances for viewing.
NASA Astrophysics Data System (ADS)
Yang Yang, Fan; Nelson, Bron; Aziz, Jonathan; Carlino, Roberto; Dono Perez, Andres; Faber, Nicolas; Foster, Cyrus; Frost, Chad; Henze, Chris; Karacalıoğlu, Arif Göktuğ; Levit, Creon; Marshall, William; Mason, James; O'Toole, Conor; Swenson, Jason; Worden, Simon P.; Stupl, Jan
2016-09-01
This work provides an efficiency analysis of the LightForce space debris collision avoidance scheme in the current debris environment and describes a simulation approach to assess its impact on the long-term evolution of the space debris environment. LightForce aims to provide just-in-time collision avoidance by utilizing photon pressure from ground-based industrial lasers. These ground stations impart minimal accelerations to increase the miss distance for a predicted conjunction between two objects. In the first part of this paper we will present research that investigates the short-term effect of a few systems consisting of 20 kW class lasers directed by 1.5 m diameter telescopes using adaptive optics. The results found such a network of ground stations to mitigate more than 85 percent of conjunctions and could lower the expected number of collisions in Low Earth Orbit (LEO) by an order of magnitude. While these are impressive numbers that indicate LightForce's utility in the short-term, the remaining 15 % of possible collisions contain (among others) conjunctions between two massive objects that would add large amount of debris if they collide. Still, conjunctions between massive objects and smaller objects can be mitigated. Hence, we choose to expand the capabilities of the simulation software to investigate the overall effect of a network of LightForce stations on the long-term debris evolution. In the second part of this paper, we will present the planned simulation approach for that effort. For the efficiency analysis of collision avoidance in the current debris environment, we utilize a simulation approach that uses the entire Two Line Element (TLE) catalog in LEO for a given day as initial input. These objects are propagated for one year and an all-on-all conjunction analysis is performed. For conjunctions that fall below a range threshold, we calculate the probability of collision and record those values. To assess efficiency, we compare a baseline (without collision avoidance) conjunction analysis with an analysis where LightForce is active. Using that approach, we take into account that collision avoidance maneuvers could have effects on third objects. Performing all-on-all conjunction analyses for extended period of time requires significant computer resources; hence we implemented this simulation utilizing a highly parallel approach on the NASA Pleiades supercomputer.
Yang, Fan Yang; Nelson, Bron; Aziz, Jonathan; Carlino, Roberto; Perez, Andres Dono; Faber, Nicolas; Foster, Cyrus; Frost, Chad; Henze, Chris; Karacalıoğlu, Arif Göktuğ; Levit, Creon; Marshall, William; Mason, James; O’Toole, Conor; Swenson, Jason; Worden, Simon P.; Stupl, Jan
2017-01-01
This work provides an efficiency analysis of the LightForce space debris collision avoidance scheme in the current debris environment and describes a simulation approach to assess its impact on the long-term evolution of the space debris environment. LightForce aims to provide just-in-time collision avoidance by utilizing photon pressure from ground-based industrial lasers. These ground stations impart minimal accelerations to increase the miss distance for a predicted conjunction between two objects. In the first part of this paper we will present research that investigates the short-term effect of a few systems consisting of 20 kW class lasers directed by 1.5 m diameter telescopes using adaptive optics. The results found such a network of ground stations to mitigate more than 85 percent of conjunctions and could lower the expected number of collisions in Low Earth Orbit (LEO) by an order of magnitude. While these are impressive numbers that indicate LightForce’s utility in the short-term, the remaining 15 % of possible collisions contain (among others) conjunctions between two massive objects that would add large amount of debris if they collide. Still, conjunctions between massive objects and smaller objects can be mitigated. Hence, we choose to expand the capabilities of the simulation software to investigate the overall effect of a network of LightForce stations on the long-term debris evolution. In the second part of this paper, we will present the planned simulation approach for that effort. For the efficiency analysis of collision avoidance in the current debris environment, we utilize a simulation approach that uses the entire Two Line Element (TLE) catalog in LEO for a given day as initial input. These objects are propagated for one year and an all-on-all conjunction analysis is performed. For conjunctions that fall below a range threshold, we calculate the probability of collision and record those values. To assess efficiency, we compare a baseline (without collision avoidance) conjunction analysis with an analysis where LightForce is active. Using that approach, we take into account that collision avoidance maneuvers could have effects on third objects. Performing all-on-all conjunction analyses for extended period of time requires significant computer resources; hence we implemented this simulation utilizing a highly parallel approach on the NASA Pleiades supercomputer. PMID:29302129
Yang, Fan Yang; Nelson, Bron; Aziz, Jonathan; Carlino, Roberto; Perez, Andres Dono; Faber, Nicolas; Foster, Cyrus; Frost, Chad; Henze, Chris; Karacalıoğlu, Arif Göktuğ; Levit, Creon; Marshall, William; Mason, James; O'Toole, Conor; Swenson, Jason; Worden, Simon P; Stupl, Jan
2016-09-01
This work provides an efficiency analysis of the LightForce space debris collision avoidance scheme in the current debris environment and describes a simulation approach to assess its impact on the long-term evolution of the space debris environment. LightForce aims to provide just-in-time collision avoidance by utilizing photon pressure from ground-based industrial lasers. These ground stations impart minimal accelerations to increase the miss distance for a predicted conjunction between two objects. In the first part of this paper we will present research that investigates the short-term effect of a few systems consisting of 20 kW class lasers directed by 1.5 m diameter telescopes using adaptive optics. The results found such a network of ground stations to mitigate more than 85 percent of conjunctions and could lower the expected number of collisions in Low Earth Orbit (LEO) by an order of magnitude. While these are impressive numbers that indicate LightForce's utility in the short-term, the remaining 15 % of possible collisions contain (among others) conjunctions between two massive objects that would add large amount of debris if they collide. Still, conjunctions between massive objects and smaller objects can be mitigated. Hence, we choose to expand the capabilities of the simulation software to investigate the overall effect of a network of LightForce stations on the long-term debris evolution. In the second part of this paper, we will present the planned simulation approach for that effort. For the efficiency analysis of collision avoidance in the current debris environment, we utilize a simulation approach that uses the entire Two Line Element (TLE) catalog in LEO for a given day as initial input. These objects are propagated for one year and an all-on-all conjunction analysis is performed. For conjunctions that fall below a range threshold, we calculate the probability of collision and record those values. To assess efficiency, we compare a baseline (without collision avoidance) conjunction analysis with an analysis where LightForce is active. Using that approach, we take into account that collision avoidance maneuvers could have effects on third objects. Performing all-on-all conjunction analyses for extended period of time requires significant computer resources; hence we implemented this simulation utilizing a highly parallel approach on the NASA Pleiades supercomputer.
Yin, Yu-Feng; Lin, Yen-Chen; Tsai, Tsung-Han; Shen, Yi-Chun; Huang, Jianjang
2013-01-15
In recent years, researchers have demonstrated negative refraction theoretically and experimentally by pumping optical power into photonic crystal (PhC) or waveguide structures. The concept of negative refraction can be used to create a perfect lens that focuses an object smaller than the wavelength. By inserting two-dimensional PhCs into the peripheral of a semiconductor light emitting structure, this study presents an electroluminescent device with negative refraction in the visible wavelength range. This approach produces polarization dependent collimation behavior in far-field radiation patterns. The modal dispersion of negative refraction results in strong group velocity modulation, and self-focusing and -defocusing behaviors are apparent from light extraction. This study further verifies experimental results by using theoretic calculations based on equifrequency contours.
A sudden brightness decrease of the young pre-MS object GM Cep
NASA Astrophysics Data System (ADS)
Munari, U.; Castellani, F.; Giannini, T.; Antoniucci, S.; Lorenzetti, D.
2017-11-01
In the framework of our EXor monitoring programme dubbed EXORCISM (EXOR OptiCal and Infrared Systematic Monitoring - Antoniucci et al. 2013 PPVI, Lorenzetti et al. 2007 ApJ 665, 1182; Lorenzetti et al. 2009 ApJ 693, 1056), we observed a new fading of the optical brightness of the Young Stellar Object (YSO) GM Cep (d=870 pc). This is a well studied variable (Semkov & Peneva 2012 APSS,338,95; Ibryamov et al. 2015 PASA,32,11; Xiao, Kroll, & Henden 2010 AJ, 139, 1527; Sicilia-Aguilar et al. 2008 ApJ,673,382-3) whose light-curve is dominated by recurrent brightness dims, interpreted as non-periodical eclipse events due to orbiting dust structures that move along the line of sight (UXor-type variability - Grinin 1988).
DOT National Transportation Integrated Search
2013-05-31
This report describes pre-crash scenarios that might be addressed by vehicle-to-vehicle communications. The focus is on crashes involving at least 1 light vehicle with a gross vehicle weight rating of 10,000 pounds or less. The 2004-2008 General Esti...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hung, Cheng-Hung
The main objective of this project was to develop a low-cost integrated substrate for rigid OLED solid-state lighting produced at a manufacturing scale. The integrated substrates could include combinations of soda lime glass substrate, light extraction layer, and an anode layer (i.e., Transparent Conductive Oxide, TCO). Over the 3 + year course of the project, the scope of work was revised to focus on the development of a glass substrates with an internal light extraction (IEL) layer. A manufacturing-scale float glass on-line particle embedding process capable of producing an IEL glass substrate having a thickness of less than 1.7mm andmore » an area larger than 500mm x 400mm was demonstrated. Substrates measuring 470mm x 370mm were used in the OLED manufacturing process for fabricating OLED lighting panels in single pixel devices as large as 120.5mm x 120.5mm. The measured light extraction efficiency (calculated as external quantum efficiency, EQE) for on-line produced IEL samples (>50%) met the project’s initial goal.« less
Yates, Thomas; Henson, Joseph; Edwardson, Charlotte; Dunstan, David; Bodicoat, Danielle H; Khunti, Kamlesh; Davies, Melanie J
2015-07-01
The aim of this study is to quantify associations between objectively measured sedentary time and markers of insulin sensitivity by considering allocation into light-intensity physical activity or moderate- to vigorous-intensity physical activity (MVPA). Participants with an increased risk of impaired glucose regulation (IGR) were recruited (Leicestershire, United Kingdom, 2010-2011). Sedentary, light-intensity physical activity and MVPA time were measured using accelerometers. Fasting and 2-hour post-challenge insulin and glucose were assessed; insulin sensitivity was calculated by HOMA-IS and Matsuda-ISI. Isotemporal substitution regression models were used. Data were analysed in 2014. 508 participants were included (average age=65years, female=34%). Reallocating 30min of sedentary time into light-intensity physical activity was associated a 5% (95% CI 1, 9%; p=0.024) difference in Matsuda-ISI after adjustment for measured confounding variables. Reallocation into MVPA was associated with a 15% (7, 25%; p<0.001) difference in HOMA-IS and 18% (8, 28%; p<0.001) difference in Matsuda-ISI. Results for light-intensity physical activity were modified by IGR status with stronger associations seen in those with IGR. Reallocating sedentary time into light-intensity physical activity or MVPA was associated with differences in insulin sensitivity, with stronger and more consistent associations seen for MVPA. Copyright © 2015. Published by Elsevier Inc.
Plasticity in neuromagnetic cortical responses suggests enhanced auditory object representation
2013-01-01
Background Auditory perceptual learning persistently modifies neural networks in the central nervous system. Central auditory processing comprises a hierarchy of sound analysis and integration, which transforms an acoustical signal into a meaningful object for perception. Based on latencies and source locations of auditory evoked responses, we investigated which stage of central processing undergoes neuroplastic changes when gaining auditory experience during passive listening and active perceptual training. Young healthy volunteers participated in a five-day training program to identify two pre-voiced versions of the stop-consonant syllable ‘ba’, which is an unusual speech sound to English listeners. Magnetoencephalographic (MEG) brain responses were recorded during two pre-training and one post-training sessions. Underlying cortical sources were localized, and the temporal dynamics of auditory evoked responses were analyzed. Results After both passive listening and active training, the amplitude of the P2m wave with latency of 200 ms increased considerably. By this latency, the integration of stimulus features into an auditory object for further conscious perception is considered to be complete. Therefore the P2m changes were discussed in the light of auditory object representation. Moreover, P2m sources were localized in anterior auditory association cortex, which is part of the antero-ventral pathway for object identification. The amplitude of the earlier N1m wave, which is related to processing of sensory information, did not change over the time course of the study. Conclusion The P2m amplitude increase and its persistence over time constitute a neuroplastic change. The P2m gain likely reflects enhanced object representation after stimulus experience and training, which enables listeners to improve their ability for scrutinizing fine differences in pre-voicing time. Different trajectories of brain and behaviour changes suggest that the preceding effect of a P2m increase relates to brain processes, which are necessary precursors of perceptual learning. Cautious discussion is required when interpreting the finding of a P2 amplitude increase between recordings before and after training and learning. PMID:24314010
Interstellar journeys in human lifetimes: numerical computations
NASA Astrophysics Data System (ADS)
Riggs, Peter J.
2017-05-01
Contrary to some contemporary accounts, a spacecraft with low acceleration can reach speeds very close to the speed of light in just a few years. In support of the teaching of special relativity, an easy to use software application has been created which calculates the values for travel times and distances to astronomical objects for such a spacecraft. This spreadsheet application may be conveniently employed as a basis for class exercises.
A Heterogeneous Multiprocessor Graphics System Using Processor-Enhanced Memories
1989-02-01
frames per second, font generation directly from conic spline descriptions, and rapid calculation of radiosity form factors. The hardware consists of...generality for rendering curved surfaces, volume data, objects dcscri id with Constructive Solid Geometry, for rendering scenes using the radiosity ...f.aces and for computing a spherical radiosity lighting model (see Section 7.6). Custom Memory Chips \\ 208 bits x 128 pixels - Renderer Board ix p o a
Creating Affording Situations: Coaching through Animate Objects
Khattab, Ahmad; Russell, Martin; Hermsdörfer, Joachim; Wing, Alan
2017-01-01
We explore the ways in which animate objects can be used to cue actions as part of coaching in Activities of Daily Living (ADL). In this case, changing the appearance or behavior of a physical object is intended to cue actions which are appropriate for a given context. The context is defined by the intention of the users, the state of the objects and the tasks for which these objects can be used. We present initial design prototypes and simple user trials which explore the impact of different cues on activity. It is shown that raising the handle of a jug, for example, not only cues the act of picking up the jug but also encourages use of the hand adjacent to the handle; that combinations of lights (on the objects) and auditory cues influence activity through reducing uncertainty; and that cueing can challenge pre-learned action sequences. We interpret these results in terms of the idea that the animate objects can be used to create affording situations, and discuss implications of this work to support relearning of ADL following brain damage or injury, such as might arise following a stroke. PMID:29019939
Viswanathan, R; Shashibhushan, K K; Subba Reddy, V V
2011-12-01
To evaluate and compare shear bond strengths of composite resins to primary enamel and dentine when the adhesives are pre-cured (light cured before the application of the resin) or co-cured (adhesive and the resin light cured together). Buccal surfaces of 80 caries-free primary molars were wet ground to create bonding surfaces on enamel and dentine and specimens mounted on acrylic blocks. Two bonding agents (Prime and Bond NT® and Xeno III®) were applied to either enamel or dentine as per manufacturer's instructions. In 40 specimens, the bonding agent was light cured immediately after the application (pre-cured). The other 40 specimens were not light cured until the composite resin application (co-cured). Resin composite cylinders were made incrementally using acrylic moulds over the adhesives and light cured. Specimens were stored in deionised water for 24 hours at room temperature. Shear bond strength was measured using an Instron universal testing machine (in MPa) and was analysed with Student's unpaired t test. Light curing the adhesive separately produced significantly higher bond strengths to primary dentine than co-curing (p<0.001). At the same time light curing the adhesive separately did not produce significantly different bond strengths to primary enamel (p>0.05). Curing sequence had no significant effect on shear bond strength of adhesives on the primary enamel. Pre-curing adhesives before curing composite resins produced greater shear bond strength to primary dentine.
Service-learning in nursing education: its impact on leadership and social justice.
Groh, Carla J; Stallwood, Lynda G; Daniels, John J
2011-01-01
Although studies suggest that service-learning is positive for students, findings reported are primarily qualitative. A convenience sample of 306 senior-level nursing students completed the Service-Learning Self-Evaluation Tool (SLSET) pre- and post-service-learning experience over a six-year span. The constructs measured were leadership skills and social justice. Paired t-tests were calculated. Statistically significant differences were noted between pre- and post-service-learning experience, with students rating themselves higher on leadership and social justice items after the experience. Cronbach's alpha for leadership and social justice were greater than 0.80. Service-learning as an educational methodology that combines community service with academic learning objectives is a viable strategy for facilitating leadership skills and increased awareness of social justice issues in nursing students.
Infants' prospective control during object manipulation in an uncertain environment.
Gottwald, Janna M; Gredebäck, Gustaf
2015-08-01
This study investigates how infants use visual and sensorimotor information to prospectively control their actions. We gave 14-month-olds two objects of different weight and observed how high they were lifted, using a Qualisys Motion Capture System. In one condition, the two objects were visually distinct (different color condition) in another they were visually identical (same color condition). Lifting amplitudes of the first movement unit were analyzed in order to assess prospective control. Results demonstrate that infants lifted a light object higher than a heavy object, especially when vision could be used to assess weight (different color condition). When being confronted with two visually identical objects of different weight (same color condition), infants showed a different lifting pattern than what could be observed in the different color condition, expressed by a significant interaction effect between object weight and color condition on lifting amplitude. These results indicate that (a) visual information about object weight can be used to prospectively control lifting actions and that (b) infants are able to prospectively control their lifting actions even without visual information about object weight. We argue that infants, in the absence of reliable visual information about object weight, heighten their dependence on non-visual information (tactile, sensorimotor memory) in order to estimate weight and pre-adjust their lifting actions in a prospective manner.
Plant experiments with light-emitting diode module in Svet space greenhouse
NASA Astrophysics Data System (ADS)
Ilieva, Iliyana; Ivanova, Tania; Naydenov, Yordan; Dandolov, Ivan; Stefanov, Detelin
Light is necessary for photosynthesis and shoot orientation in the space plant growth facilities. Light modules (LM) must provide sufficient photosynthetic photon flux for optimal efficiency of photosynthetic processes and also meet the constraints for power, volume and mass. A new LM for SVET Space Greenhouse using Cree R XLamp R 7090 XR light-emitting diodes (LEDs) is developed. Three types of monochromic LEDs emitting in the red, green, and blue region of the spectrum are used. The new LM contains 36 LED spots - 30 LED spots with one red, green and blue LED and 6 LED spots with three red LEDs. DMX programming device controls the LED spots and can set 231 levels of light intensity thus achieving Photosynthetic Photon Flux Density (PPFD) in the range 0-400 µmol.m-2 .s-1 and different percentages of the red, green and blue light, depending on the experimental objectives. Two one-month experiments with "salad-type" plants - lettuce and chicory were carried at 400 µmol.m-2 .s-1 PPFD (high light - HL) and 220 µmol.m-2 .s-1 PPFD (low light - LL) and composition 70% red, 20% green and 10% blue light. In vivo modulated chlorophyll fluorescence was measured by a PAM fluorometer on leaf discs and the following parameters: effective quantum yield of Photosystem II (ΦP SII ) and non-photochemical quenching (NPQ) were calculated. Both lettuce and chicory plants grown at LL express higher photochemical activity of Photosystem II (PSII) than HL grown plants, evaluated by the actual PSII quantum yield, ΦP SII . The calculated steady state NPQ values did not differ significantly in lettuce and chicory. The rapid phase of the NPQ increase was accelerated in all studied LL leaves. In conclusion low light conditions ensured more effective functioning of PSII than HL when lettuce and chicory plants were grown at 70% red, 20% green and 10% blue light composition.
Distribution of light in the human retina under natural viewing conditions
NASA Astrophysics Data System (ADS)
Gibert, Jorge C.
Age-related macular degeneration (AMD) is the leading cause of blindness inAmerica. The fact that AMD wreaks most of the damage in the center of the retina raises the question of whether light, integrated over long periods, is more concentrated in the macula. A method, based on eye-tracking, was developed to measure the distribution of light in the retina under natural viewing conditions. The hypothesis was that integrated over time, retinal illumination peaked in the macula. Additionally a possible relationship between age and retinal illumination was investigated. The eye tracker superimposed the subject's gaze position on a video recorded by a scene camera. Five informed subjects were employed in feasibility tests, and 58 naive subjects participated in 5 phases. In phase 1 the subjects viewed a gray-scale image. In phase 2, they observed a sequence of photographic images. In phase 3 they viewed a video. In phase 4, they worked on a computer; in phase 5, the subjects walked around freely. The informed subjects were instructed to gaze at bright objects in the field of view and then at dark objects. Naive subjects were allowed to gaze freely for all phases. Using the subject's gaze coordinates, and the video provided by the scene camera, the cumulative light distribution on the retina was calculated for ˜15° around the fovea. As expected for control subjects, cumulative retinal light distributions peaked and dipped in the fovea when they gazed at bright or dark objects respectively. The light distribution maps obtained from the naive subjects presented a tendency to peak in the macula for phases 1, 2, and 3, a consistent tendency in phase 4 and a variable tendency in phase 5. The feasibility of using an eye-tracker system to measure the distribution of light in the retina was demonstrated, thus helping to understand the role played by light exposure in the etiology of AMD. Results showed that a tendency for light to peak in the macula is a characteristic of some individuals and of certain tasks. In these situations, risk of AMD could be increased. No significant difference was observed based on age.
Brown, Mary Jean; Jacobs, David E.
2011-01-01
Objectives. We examined the relationship between self-reported inadequate residential natural light and risk for depression or falls among adults aged 18 years or older. Methods. Generalized estimating equations were used to calculate the odds of depression or falls in participants with self-reported inadequate natural residential light vs. those reporting adequate light (n=6,017) using data from the World Health Organization's Large Analysis and Review of European Housing and Health Survey, a large cross-sectional study of housing and health in representative populations from eight European cities. Results. Participants reporting inadequate natural light in their dwellings were 1.4 times (95% confidence interval [CI] 1.2,1.7) as likely to report depression and 1.5 times (95% CI 1.2, 1.9) as likely to report a fall compared with those satisfied with their dwelling's light. After adjustment for major confounders, the likelihood of depression changed slightly, while the likelihood of a fall increased to 2.5 (95% CI 1.5, 4.2). Conclusion. Self-reported inadequate light in housing is independently associated with depression and falls. Increasing light in housing, a relatively inexpensive intervention, may improve two distinct health conditions. PMID:21563721
NASA Astrophysics Data System (ADS)
Stritzinger, M. D.; Anderson, J. P.; Contreras, C.; Heinrich-Josties, E.; Morrell, N.; Phillips, M. M.; Anais, J.; Boldt, L.; Busta, L.; Burns, C. R.; Campillay, A.; Corco, C.; Castellon, S.; Folatelli, G.; González, C.; Holmbo, S.; Hsiao, E. Y.; Krzeminski, W.; Salgado, F.; Serón, J.; Torres-Robledo, S.; Freedman, W. L.; Hamuy, M.; Krisciunas, K.; Madore, B. F.; Persson, S. E.; Roth, M.; Suntzeff, N. B.; Taddia, F.; Li, W.; Filippenko, A. V.
2018-02-01
The first phase of the Carnegie Supernova Project (CSP-I) was a dedicated supernova follow-up program based at the Las Campanas Observatory that collected science data of young, low-redshift supernovae between 2004 and 2009. Presented in this paper is the CSP-I photometric data release of low-redshift stripped-envelope core-collapse supernovae. The data consist of optical (uBgVri) photometry of 34 objects, with a subset of 26 having near-infrared (YJH) photometry. Twenty objects have optical pre-maximum coverage with a subset of 12 beginning at least five days prior to the epoch of B-band maximum brightness. In the near-infrared, 17 objects have pre-maximum observations with a subset of 14 beginning at least five days prior to the epoch of J-band maximum brightness. Analysis of this photometric data release is presented in companion papers focusing on techniques to estimate host-galaxy extinction and the light-curve and progenitor star properties of the sample. The analysis of an accompanying visual-wavelength spectroscopy sample of 150 spectra will be the subject of a future paper. Based on observations collected at Las Campanas Observatory.Tables 2-8 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/609/A134
The effect of light rail transit on body mass index and physical activity.
MacDonald, John M; Stokes, Robert J; Cohen, Deborah A; Kofner, Aaron; Ridgeway, Greg K
2010-08-01
The built environment can constrain or facilitate physical activity. Most studies of the health consequences of the built environment face problems of selection bias associated with confounding effects of residential choice and transportation decisions. To examine the cross-sectional associations between objective and perceived measures of the built environment; BMI; obesity (BMI>30 kg/m(2)); and meeting weekly recommended physical activity (RPA) levels through walking and vigorous exercise. To assess the effect of using light rail transit (LRT) system on BMI, obesity, and weekly RPA levels. Data were collected on individuals before (July 2006-February 2007) and after (March 2008-July 2008) completion of an LRT system in Charlotte NC. BMI, obesity, and physical activity levels were calculated for a comparison of these factors pre- and post-LRT construction. A propensity score weighting approach adjusted for differences in baseline characteristics among LRT and non-LRT users. Data were analyzed in 2009. More-positive perceptions of one's neighborhood at baseline were associated with a -0.36 (p<0.05) lower BMI; 15% lower odds (95% CI=0.77, 0.94) of obesity; 9% higher odds (95% CI=0.99, 1.20) of meeting weekly RPA through walking; and 11% higher odds (95% CI=1.01, 1.22) of meeting RPA levels of vigorous exercise. The use of LRT to commute to work was associated with an average -1.18 reduction in BMI (p<0.05) and an 81% reduced odds (95% CI=0.04, 0.92) of becoming obese over time. The results of this study suggest that improving neighborhood environments and increasing the public's use of LRT systems could provide improvements in health outcomes for millions of individuals. 2010 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.
Moody, J D; Clancy, T J; Frieders, G; Celliers, P M; Ralph, J; Turnbull, D P
2014-11-01
Laser pre-pulse and early-time laser reflection from the hohlraum wall onto the capsule (termed "glint") can cause capsule imprint and unwanted early-time shocks on indirect drive implosion experiments. In a minor modification to the existing velocity interferometer system for any reflector diagnostic on NIF a fast-response vacuum photodiode was added to detect this light. The measurements show evidence of laser pre-pulse and possible light reflection off the hohlraum wall and onto the capsule.
Bhuvaneshwari, M; Sagar, Bhawana; Doshi, Siddharth; Chandrasekaran, N; Mukherjee, Amitava
2017-02-01
This study evaluated the toxicity potential of ZnO and TiO 2 nanoparticles under pre-UV-A irradiation and visible light condition on Artemia salina. The nanoparticle suspension was prepared in seawater medium and exposed under pre-UV-A (0.23 mW/cm 2 ) and visible light (0.18 mW/cm 2 ) conditions. The aggregation profiles of both nanoparticles (NPs) and dissolution of ZnO NPs under both irradiation conditions at various kinetic intervals (1, 24, 48 h) were studied. The 48-h LC 50 values were found to be 27.62 and 71.63 mg/L for ZnO NPs and 117 and 120.9 mg/L for TiO 2 NPs under pre-UV-A and visible light conditions. ZnO NPs were found to be more toxic to A. salina as compared to TiO 2 NPs. The enhanced toxicity was observed under pre-UV-A-irradiated ZnO NPs, signifying its phototoxicity. Accumulation of ZnO and TiO 2 NPs into A. salina depends on the concentration of particles and type irradiations. Elimination of accumulated nanoparticles was also evident under both irradiation conditions. Other than ZnO NPs, the dissolved Zn 2+ also had a significant effect on toxicity and accumulation in A. salina. Increased catalase (CAT) activity in A. salina indicates the generation of oxidative stress due to NP interaction. Thus, this study provides an understanding of the toxicity of photoreactive ZnO and TiO 2 NPs as related to the effects of pre-UV-A and visible light irradiation.
Münch, M; Scheuermaier, KD; Zhang, R; Dunne, SP; Guzik, AM; Silva, EJ; Ronda, JM; Duffy, JF
2011-01-01
Evening bright light exposure is reported to ameliorate daytime sleepiness and age-related sleep complaints, and also delays the timing of circadian rhythms. We tested whether evening light exposure given to older adults with sleep-wake complaints would delay the timing of their circadian rhythms with respect to their sleep timing, thereby reducing evening sleepiness and improving subsequent sleep quality. We examined the impact of evening light exposure from two different light sources on subjective alertness, EEG activity during wakefulness, and sleep stages. Ten healthy older adults with sleep complaints (mean age=63.3 yrs; 6F) participated in a 13-day study. After three baseline days, circadian phase was assessed. On the evening of days 5–8 the subjects were exposed for 2 h to either polychromatic blue-enriched white light or standard white fluorescent light, and on the following day circadian phase was re-assessed. Subjects were allowed to leave the laboratory during all but the two days when the circadian phase assessment took place. Evening assessments of subjective alertness, and wake and sleep EEG data were analyzed. Subjective alertness and wake EEG activity in the alpha range (9.75–11.25 Hz) were significantly higher during light exposures when compared to the pre-light exposure evening (p<0.05). The light exposures produced circadian phase shifts and significantly prolonged latency to rapid eye-movement (REM) sleep for both light groups (p<0.05). The increase in wake EEG alpha activity during the light exposures was negatively correlated with REM sleep duration (p<0.05). Evening light exposure could benefit older adults with early evening sleepiness, without negatively impacting the subsequent sleep episode. PMID:21664380
Mere exposure alters category learning of novel objects.
Folstein, Jonathan R; Gauthier, Isabel; Palmeri, Thomas J
2010-01-01
We investigated how mere exposure to complex objects with correlated or uncorrelated object features affects later category learning of new objects not seen during exposure. Correlations among pre-exposed object dimensions influenced later category learning. Unlike other published studies, the collection of pre-exposed objects provided no information regarding the categories to be learned, ruling out unsupervised or incidental category learning during pre-exposure. Instead, results are interpreted with respect to statistical learning mechanisms, providing one of the first demonstrations of how statistical learning can influence visual object learning.
Mere Exposure Alters Category Learning of Novel Objects
Folstein, Jonathan R.; Gauthier, Isabel; Palmeri, Thomas J.
2010-01-01
We investigated how mere exposure to complex objects with correlated or uncorrelated object features affects later category learning of new objects not seen during exposure. Correlations among pre-exposed object dimensions influenced later category learning. Unlike other published studies, the collection of pre-exposed objects provided no information regarding the categories to be learned, ruling out unsupervised or incidental category learning during pre-exposure. Instead, results are interpreted with respect to statistical learning mechanisms, providing one of the first demonstrations of how statistical learning can influence visual object learning. PMID:21833209
LED Curing Lights and Temperature Changes in Different Tooth Sites
Armellin, E.; Bovesecchi, G.; Coppa, P.; Pasquantonio, G.; Cerroni, L.
2016-01-01
Objectives. The aim of this in vitro study was to assess thermal changes on tooth tissues during light exposure using two different LED curing units. The hypothesis was that no temperature increase could be detected within the dental pulp during polymerization irrespective of the use of a composite resin or a light-curing unit. Methods. Caries-free human first molars were selected, pulp residues were removed after root resection, and four calibrated type-J thermocouples were positioned. Two LED lamps were tested; temperature measurements were made on intact teeth and on the same tooth during curing of composite restorations. The data was analyzed by one-way analysis of variance (ANOVA), Wilcoxon test, Kruskal-Wallis test, and Pearson's χ 2. After ANOVA, the Bonferroni multiple comparison test was performed. Results. Polymerization data analysis showed that in the pulp chamber temperature increase was higher than that without resin. Starlight PRO, in the same condition of Valo lamp, showed a lower temperature increase in pre- and intrapolymerization. A control group (without composite resin) was evaluated. Significance. Temperature increase during resin curing is a function of the rate of polymerization, due to the exothermic polymerization reaction, the energy from the light unit, and time of exposure. PMID:27195282
Restoring the spatial resolution of refocus images on 4D light field
NASA Astrophysics Data System (ADS)
Lim, JaeGuyn; Park, ByungKwan; Kang, JooYoung; Lee, SeongDeok
2010-01-01
This paper presents the method for generating a refocus image with restored spatial resolution on a plenoptic camera, which functions controlling the depth of field after capturing one image unlike a traditional camera. It is generally known that the camera captures 4D light field (angular and spatial information of light) within a limited 2D sensor and results in reducing 2D spatial resolution due to inevitable 2D angular data. That's the reason why a refocus image is composed of a low spatial resolution compared with 2D sensor. However, it has recently been known that angular data contain sub-pixel spatial information such that the spatial resolution of 4D light field can be increased. We exploit the fact for improving the spatial resolution of a refocus image. We have experimentally scrutinized that the spatial information is different according to the depth of objects from a camera. So, from the selection of refocused regions (corresponding depth), we use corresponding pre-estimated sub-pixel spatial information for reconstructing spatial resolution of the regions. Meanwhile other regions maintain out-of-focus. Our experimental results show the effect of this proposed method compared to existing method.
LED Curing Lights and Temperature Changes in Different Tooth Sites.
Armellin, E; Bovesecchi, G; Coppa, P; Pasquantonio, G; Cerroni, L
2016-01-01
Objectives. The aim of this in vitro study was to assess thermal changes on tooth tissues during light exposure using two different LED curing units. The hypothesis was that no temperature increase could be detected within the dental pulp during polymerization irrespective of the use of a composite resin or a light-curing unit. Methods. Caries-free human first molars were selected, pulp residues were removed after root resection, and four calibrated type-J thermocouples were positioned. Two LED lamps were tested; temperature measurements were made on intact teeth and on the same tooth during curing of composite restorations. The data was analyzed by one-way analysis of variance (ANOVA), Wilcoxon test, Kruskal-Wallis test, and Pearson's χ (2). After ANOVA, the Bonferroni multiple comparison test was performed. Results. Polymerization data analysis showed that in the pulp chamber temperature increase was higher than that without resin. Starlight PRO, in the same condition of Valo lamp, showed a lower temperature increase in pre- and intrapolymerization. A control group (without composite resin) was evaluated. Significance. Temperature increase during resin curing is a function of the rate of polymerization, due to the exothermic polymerization reaction, the energy from the light unit, and time of exposure.
batman: BAsic Transit Model cAlculatioN in Python
NASA Astrophysics Data System (ADS)
Kreidberg, Laura
2015-10-01
batman provides fast calculation of exoplanet transit light curves and supports calculation of light curves for any radially symmetric stellar limb darkening law. It uses an integration algorithm for models that cannot be quickly calculated analytically, and in typical use, the batman Python package can calculate a million model light curves in well under ten minutes for any limb darkening profile.
NASA Astrophysics Data System (ADS)
Ma, J.; Liu, Q.
2018-02-01
This paper presents an improved short circuit calculation method, based on pre-computed surface to determine the short circuit current of a distribution system with multiple doubly fed induction generators (DFIGs). The short circuit current, injected into power grid by DFIG, is determined by low voltage ride through (LVRT) control and protection under grid fault. However, the existing methods are difficult to calculate the short circuit current of DFIG in engineering practice due to its complexity. A short circuit calculation method, based on pre-computed surface, was proposed by developing the surface of short circuit current changing with the calculating impedance and the open circuit voltage. And the short circuit currents were derived by taking into account the rotor excitation and crowbar activation time. Finally, the pre-computed surfaces of short circuit current at different time were established, and the procedure of DFIG short circuit calculation considering its LVRT was designed. The correctness of proposed method was verified by simulation.
Evaluation of image quality metrics for the prediction of subjective best focus.
Kilintari, Marina; Pallikaris, Aristophanis; Tsiklis, Nikolaos; Ginis, Harilaos S
2010-03-01
Seven existing and three new image quality metrics were evaluated in terms of their effectiveness in predicting subjective cycloplegic refraction. Monochromatic wavefront aberrations (WA) were measured in 70 eyes using a Shack-Hartmann based device (Complete Ophthalmic Analysis System; Wavefront Sciences). Subjective cycloplegic spherocylindrical correction was obtained using a standard manifest refraction procedure. The dioptric amount required to optimize each metric was calculated and compared with the subjective refraction result. Metrics included monochromatic and polychromatic variants, as well as variants taking into consideration the Stiles and Crawford effect (SCE). WA measurements were performed using infrared light and converted to visible before all calculations. The mean difference between subjective cycloplegic and WA-derived spherical refraction ranged from 0.17 to 0.36 diopters (D), while paraxial curvature resulted in a difference of 0.68 D. Monochromatic metrics exhibited smaller mean differences between subjective cycloplegic and objective refraction. Consideration of the SCE reduced the standard deviation (SD) of the difference between subjective and objective refraction. All metrics exhibited similar performance in terms of accuracy and precision. We hypothesize that errors pertaining to the conversion between infrared and visible wavelengths rather than calculation method may be the limiting factor in determining objective best focus from near infrared WA measurements.
Holographic fluorescence mapping using space-division matching method
NASA Astrophysics Data System (ADS)
Abe, Ryosuke; Hayasaki, Yoshio
2017-10-01
Three-dimensional mapping of fluorescence light sources was performed by using self-interference digital holography. The positions of the sources were quantitatively determined by using Gaussian fitting of the axial and lateral intensity distributions obtained from diffraction calculations through position calibration from the observation space to the sample space. A space-division matching method was developed to perform the mapping of many fluorescence light sources, in this experiment, 500 nm fluorescent nanoparticles fixed in gelatin. A fluorescence digital holographic microscope having a 60 × objective lens with a numerical aperture of 1.25 detected 13 fluorescence light sources in a measurable region with a radius of ∼ 20 μm and a height of ∼ 5 μm. It was found that the measurable region had a conical shape resulting from the overlap between two beams.
Measuring the speed resolution of extensive air showers at the Southern Pierre Auger Observatory
NASA Astrophysics Data System (ADS)
Gesterling, Kathleen; Sarazin, Fred
2009-10-01
Ultra-high energy cosmic rays induce extensive air showers (EASs) in Earth's atmosphere which are assumed to propagate at the speed of light. The fluorescence detector (FD) at the Southern Pierre Auger Observatory detects the light signal from the EAS and directly measures the energy of the cosmic ray. When two or more FD sites observe an event, the geometry of the shower can be calculated independently of the velocity it is traveling. It is then possible to fit the time profile recorded in the FD using the shower speed as a free parameter. The analysis of a collection of stereo events allowed us to determine with what speed resolution we can measure EASs with sensitivity to subluminal components. Knowing the speed resolution we can look for objects propagating significantly below the speed of light.
Father participation with mothers in the Signposts program: an initial investigation.
May, Fiona S; McLean, Louise A; Anderson, Angelika; Hudson, Alan; Cameron, Christine; Matthews, Jan
2013-03-01
The Signposts program is an evidence-based intervention system for parents of children with intellectual disability and problem behaviours. This study provided an initial investigation of the outcomes for mothers associated with father participation in Signposts, using data collected from the Signposts Statewide project, conducted in Victoria, Australia. Data from Signposts Statewide were analysed, with the effect size Cohen's d and 95% confidence interval around d calculated for pre- to post-program changes for 134 mothers who participated in Signposts with fathers and 483 mothers who participated without fathers. Although mothers in both groups benefitted from the program, as evidenced by pre- to post-program improvements across all measures, the mean effect size was notably larger for mothers who participated in Signposts with fathers. These results highlight possible further program benefits for mothers who participate in Signposts with fathers, and are of particular significance in light of research describing the increased stress experienced by mothers of children with a disability.
Laser Light Scattering by Shock Waves
NASA Technical Reports Server (NTRS)
Panda, J.; Adamovsky, G.
1995-01-01
Scattering of coherent light as it propagates parallel to a shock wave, formed in front of a bluff cylindrical body placed in a supersonic stream, is studied experimentally and numerically. Two incident optical fields are considered. First, a large diameter collimated beam is allowed to pass through the shock containing flow. The light intensity distribution in the resultant shadowgraph image, measured by a low light CCD camera, shows well-defined fringes upstream and downstream of the shadow cast by the shock. In the second situation, a narrow laser beam is brought to a grazing incidence on the shock and the scattered light, which appears as a diverging sheet from the point of interaction, is visualized and measured on a screen placed normal to the laser path. Experiments are conducted on shocks formed at various free-stream Mach numbers, M, and total pressures, P(sub 0). It is found that the widths of the shock shadows in a shadowgraph image become independent of M and P(sub 0) when plotted against the jump in the refractive index, (Delta)n, created across the shock. The total scattered light measured from the narrow laser beam and shock interaction also follows the same trend. In the numerical part of the study, the shock is assumed to be a 'phase object', which introduces phase difference between the upstream and downstream propagating parts of the light disturbances. For a given shape and (Delta)n of the bow shock the phase and amplitude modulations are first calculated by ray tracing. The wave front is then propagated to the screen using the Fresnet diffraction equation. The calculated intensity distribution, for both of the incident optical fields, shows good agreement with the experimental data.
NASA Astrophysics Data System (ADS)
Baek, Sang-In; Kim, Sung-Jo; Kim, Jong-Hyun
2015-09-01
Although the homeotropic alignment of liquid crystals is widely used in LCD TVs, no easy method exists to measure its anchoring coefficient. In this study, we propose an easy and convenient measurement technique in which a polarizing optical microscope is used in the reflective mode with an objective lens having a low depth of focus. All measurements focus on the reflection of light near the interface between the liquid crystal and alignment layer. The change in the reflected light is measured by applying an electric field. We model the response of the director of the liquid crystal to the electric field and, thus, the change in reflectance. By adjusting the extrapolation length in the calculation, we match the experimental and calculated results and obtain the anchoring coefficient. In our experiment, the extrapolation lengths were 0.31 ± 0.04 μm, 0.32 ± 0.08 μm, and 0.23 ± 0.05 μm for lecithin, AL-64168, and SE-5662, respectively.
Kepler Uniform Modeling of KOIs: MCMC Notes for Data Release 25
NASA Technical Reports Server (NTRS)
Hoffman, Kelsey L.; Rowe, Jason F.
2017-01-01
This document describes data products related to the reported planetary parameters and uncertainties for the Kepler Objects of Interest (KOIs) based on a Markov-Chain-Monte-Carlo (MCMC) analysis. Reported parameters, uncertainties and data products can be found at the NASA Exoplanet Archive . The codes used for this data analysis are available on the Github website (Rowe 2016). The relevant paper for details of the calculations is Rowe et al. (2015). The main differences between the model fits discussed here and those in the DR24 catalogue are that the DR25 light curves were used in the analysis, our processing of the MAST light curves took into account different data flags, the number of chains calculated was doubled to 200 000, and the parameters which are reported are based on a damped least-squares fit, instead of the median value from the Markov chain or the chain with the lowest 2 as reported in the past.
Hall station and camera system operation and maintenance manual
NASA Technical Reports Server (NTRS)
Piekutowski, A. J.; Strader, E. A.
1986-01-01
The major components of the Hall station and camera system are described. The Hall film record of an event provides the time of flight of the projectile between the slits. A time mark generator is used to supply extremely short pulses of light at a known frequency. These pulses of light are used to produce timing marks on the edge of the film. Comparison of these marks with the spacing of the projectile images provides the information necessary to determine the time of flight of the projectile. Since the slits are installed with a known separation distance, calculation of the velocity of any object passing both slits is a simple matter.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Houser, Kevin W.; Royer, Michael P.; David, Aurelien
A system for evaluating the color rendition of light sources was recently published as IES TM-30-15 IES Method for Evaluating Light Source Color Rendition. The system includes a fidelity index (Rf) to quantify similarity to a reference illuminant, a relative-gamut index (Rg) to quantify saturation relative to a reference illuminant, and a color vector icon that visually presents information about color rendition. The calculation employs CAM02-UCS and uses a newly-developed set of reflectance functions, comprising 99 color evaluation samples (CES). The CES were down-selected from 105,000 real object samples and are uniformly distributed in color space (fairly representing different colors)more » and wavelength space (avoiding artificial increase of color rendition values by selective optimization).« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kinzey, Bruce R.; Myer, Michael
This report documents the results of a collaborative project to demonstrate a solid state lighting (SSL) general illumination product in an outdoor area walkway application. In the project, six light-emitting diode (LED) luminaires were installed to replace six existing high pressure sodium (HPS) luminaires mounted on 14-foot poles on a set of exterior walkways and stairs at the Federal Aviation Administration (FAA) William J. Hughes Technical Center in Atlantic City, New Jersey, during December, 2007. The effort was a U.S. Department of Energy (DOE) SSL Technology Gateway Demonstration that involved a collaborative teaming agreement between DOE, FAA and Ruud Lightingmore » (and their wholly owned division, Beta LED). Pre- and post-installation power and illumination measurements were taken and used in calculations of energy savings and related economic payback, while personnel impacted by the new lights were provided questionnaires to gauge their perceptions and feedback. The SSL product demonstrated energy savings of over 25% while maintaining illuminance levels and improving illuminance uniformity. PNNL's economic analysis yielded a variety of potential payback results depending on the assumptions used. In the best case, replacing HPS with the LED luminaire can yield a payback as low as 3 years. The new lamps were quite popular with the affected personnel, who gave the lighting an average score of 4.46 out of 5 for improvement.« less
Erasmus, M. Frank; Matlawska-Wasowska, Ksenia; Kinjyo, Ichiko; Mahajan, Avanika; Winter, Stuart S.; Xu, Li; Horowitz, Michael; Lidke, Diane S.; Wilson, Bridget S.
2017-01-01
The pre-B cell receptor (pre-BCR) is an immature form of the BCR critical for early B lymphocyte development. It is composed of the membrane-bound immunoglobulin (Ig) heavy chain, surrogate light chain components, and the signaling subunits Igα and Igβ. We developed monovalent Quantum Dot (QD)-labeled probes specific for Igβ to study the behavior of pre-BCRs engaged in autonomous, ligand-independent signaling in live B cells. Single-particle tracking revealed that QD-labeled pre-BCRs engaged in transient, but frequent, homotypic interactions. Receptor motion was correlated at short separation distances, consistent with the formation of dimers and higher-order oligomers. Repeated encounters between diffusing pre-BCRs appeared to reflect transient co-confinement in plasma membrane domains. In human B cell precursor acute lymphoblastic leukemia (BCP-ALL) cells, we showed that frequent, short-lived, homotypic pre-BCR interactions stimulated survival signals, including expression of BCL6, which encodes a transcriptional repressor. These survival signals were blocked by inhibitory monovalent antigen-binding antibody fragments (Fabs) specific for the surrogate light chain components of the pre-BCR or by inhibitors of the tyrosine kinases Lyn and Syk. For comparison, we evaluated pre-BCR aggregation mediated by dimeric galectin-1, which has binding sites for carbohydrate and for the λ5 component of the surrogate light chain. Galectin-1 binding resulted in the formation of large, highly immobile pre-BCR aggregates, which was partially relieved by the addition of lactose to prevent the crosslinking of galectin-BCR complexes to other glycosylated membrane components. Analysis of the pre-BCR and its signaling partners suggested that they could be potential targets for combination therapy in BCP-ALL. PMID:27899526
DARK-FIELD ILLUMINATION SYSTEM
Norgren, D.U.
1962-07-24
A means was developed for viewing objects against a dark background from a viewing point close to the light which illuminates the objects and under conditions where the back scattering of light by the objects is minimal. A broad light retro-directing member on the opposite side of the objects from the light returns direct light back towards the source while directing other light away from the viewing point. The viewing point is offset from the light and thus receives only light which is forwardly scattered by an object while returning towards the source. The object is seen, at its true location, against a dark background. The invention is particularly adapted for illuminating and viewing nuclear particle tracks in a liquid hydrogen bubble chamber through a single chamber window. (AEC)
NASA Astrophysics Data System (ADS)
Ivanov, Arkady P.; Barun, Vladimir V.
2007-05-01
A calculation scheme and an algorithm to simultaneously diagnose several structural and biophysical parameters of skin by reflected light are constructed in the paper. The procedure is based the fact that, after absorption and scattering, light reflected by tissue contains information on its optically active chromophores and structure. The problem on isolating the desired parameters is a spectroscopic one under multiple scattering conditions. The latter considerably complicates the solution of the problem and requires the elaboration of an approach that is specific to the object studied. The procedure presented in the paper is based on spectral tissue model properties proposed earlier and engineering methods for solving the radiative transfer equation. The desired parameters are melanin and blood volume fractions, f and c, epidermis thickness d, mean diameter D of capillaries, and blood oxygenation degree S. Spectral diffuse reflectance R(λ) of skin over the range of 400 to 850 nm was calculated as a first stage. Then the sensitivity of R(λ) to the above parameters was studied to optimize the algorithm by wavelengths and to propose an experimental scheme for diagnostics. It is shown that blood volume fraction and f*d product can be rather surely determined by the reflected green -- red light. One can find f and d separately as well as D by the blue reflectance. The last stage is the derivation of S at about 600 nm.
Linear CCD attitude measurement system based on the identification of the auxiliary array CCD
NASA Astrophysics Data System (ADS)
Hu, Yinghui; Yuan, Feng; Li, Kai; Wang, Yan
2015-10-01
Object to the high precision flying target attitude measurement issues of a large space and large field of view, comparing existing measurement methods, the idea is proposed of using two array CCD to assist in identifying the three linear CCD with multi-cooperative target attitude measurement system, and to address the existing nonlinear system errors and calibration parameters and more problems with nine linear CCD spectroscopic test system of too complicated constraints among camera position caused by excessive. The mathematical model of binocular vision and three linear CCD test system are established, co-spot composition triangle utilize three red LED position light, three points' coordinates are given in advance by Cooperate Measuring Machine, the red LED in the composition of the three sides of a triangle adds three blue LED light points as an auxiliary, so that array CCD is easier to identify three red LED light points, and linear CCD camera is installed of a red filter to filter out the blue LED light points while reducing stray light. Using array CCD to measure the spot, identifying and calculating the spatial coordinates solutions of red LED light points, while utilizing linear CCD to measure three red LED spot for solving linear CCD test system, which can be drawn from 27 solution. Measured with array CCD coordinates auxiliary linear CCD has achieved spot identification, and has solved the difficult problems of multi-objective linear CCD identification. Unique combination of linear CCD imaging features, linear CCD special cylindrical lens system is developed using telecentric optical design, the energy center of the spot position in the depth range of convergence in the direction is perpendicular to the optical axis of the small changes ensuring highprecision image quality, and the entire test system improves spatial object attitude measurement speed and precision.
Taipale, Heidi; Tanskanen, Antti; Koponen, Marjaana; Tolppanen, Anna-Maija; Tiihonen, Jari; Hartikainen, Sirpa
2016-01-01
Background PRE2DUP is a modeling method that generates drug use periods (ie, when drug use started and ended) from drug purchases recorded in dispensing-based register data. It is based on the evaluation of personal drug purchasing patterns and considers hospital stays, possible stockpiling of drugs, and package information. Objective The objective of this study was to investigate person-level agreement between self-reported drug use in the interview and drug use modeled from dispensing data with PRE2DUP method for various drug classes used by older persons. Methods Self-reported drug use was assessed from the GeMS Study including a random sample of persons aged ≥75 years from the city of Kuopio, Finland, in 2006. Drug purchases recorded in the Prescription register data of these persons were modeled to determine drug use periods with PRE2DUP modeling method. Agreement between self-reported drug use on the interview date and drug use calculated from register-based data was compared in order to find the frequently used drugs and drug classes, which was evaluated by Cohen’s kappa. Kappa values 0.61–0.80 were considered to represent good and 0.81–1.00 as very good agreement. Results Among 569 participants with mean age of 82 years, the agreement between interview and register data was very good for 75% and very good or good for 93% of the studied drugs or drug classes. Good or very good agreement was observed for drugs that are typically used on regular bases, whereas “as needed” drugs represented poorer results. Conclusion PRE2DUP modeling method validly describes regular drug use among older persons. For most of drug classes investigated, PRE2DUP-modeled register data described drug use as well as interview-based data which are more time-consuming to collect. Further studies should be conducted by comparing it with other methods and in different drug user populations. PMID:27785101
Bhat, B; Sharma, V D
2015-03-01
Valeriana officinalis is an important medicinal herb commonly found in Kashmir valley. This study forms an important preliminary step for in-vitro micro propagation of V. officinalis from breaking the seed dormancy, inducing rapid seed germination and its subsequent micro propagation. We investigated the influence of pretreatment of V. officinalis seeds with reduced temperature and light on seed germination and in-vitro propagation. Culture of explants from cultivated seeds have demonstrated its potential for in vitro propagation and plantlet regeneration. Individual as well as combinations of treatments such as temperature and light availability influenced the germination of seeds variedly. Unchilled seeds of V. officinalis were given dip in GA3 (200 ppm) for 24, 48 and 120 h. Seeds treated with GA3 for 24 h and kept in darkness showed the best results, i.e. 48%. Seeds pretreated with GA3 for 120 h and incubated in dark showed 40% germination. Pre-chilling up to 72 h and kept in light showed maximum germination of 60% followed by 40% kept in darkness. Pre-chilling for 48 h resulted in 40 and 25% seed germination in light and darkness, respectively. GA3 pre-treatment for 72 h and 24 h pre chilling were most effective in inducing seed germination. Maximum shoot response was obtained on MS enriched with BAP (1 mg/L) + IAA (0.1 mg/L) combinations using shoot tips as explants. Multiple shoot regeneration from shoot apices was recorded on BAP (1 mg/L) and BAP (1 mg/L) + IAA (0.1 mg/L).
NASA Astrophysics Data System (ADS)
Fiore, Antonio; Scarcelli, Giuliano
2017-02-01
Brillouin microscopy allows high-resolution mapping of the mechanical properties of a sample by measuring the spectra of acoustically induced light scattering therein, and thus has been widely investigated for biomedical application. Measuring the Brillouin spectral shift is challenging when the light is focused onto the interfaces between two materials of different refractive index, because a sizeable portion of the incident light is Fresnel-reflected into the Brillouin spectrometer. To address this need, here, we designed a Brillouin confocal microscope in which the specular reflection at the interface between two materials is physically rejected without significant loss to the Brillouin signal. To achieve this goal, we illuminate the sample with a small-diameter Gaussian beam focused by a high numerical aperture objective lens. In the collection path, the beam reflected from the sample has the same diameter as the incident beam, while the scattered light beam is as large as the clear aperture of the microscope objective. Therefore, using a small blocking filter allows to efficiently reject the reflected light. We calculated the tradeoff between extinction improvement and signal loss when the diameter of the blocking filter is changed. Experimentally, we demonstrated extinction improvement of over 60dB with only 30% signal loss while achieving submicron resolutions. This innovation can be useful for in vivo measurements of the cornea to avoid artifacts in the epithelium and anterior portions of the stroma, as well as to investigate cells cultured on glass coverslips without necessity of index-matching materials.
NIR spectrometer using a Schottky photodetector enhanced by grating-based SPR.
Chen, Wenjing; Kan, Tetsuo; Ajiki, Yoshiharu; Matsumoto, Kiyoshi; Shimoyama, Isao
2016-10-31
We present a near-infrared (NIR) spectrum measurement method using a Schottky photodetector enhanced by surface plasmon resonance (SPR). An Au grating was fabricated on an n-type silicon wafer to form a Schottky barrier and act as an SPR coupler. The resulting photodetector provides wavelength-selective photodetection depending on the SPR coupling angle. A matrix was pre-calculated to describe this characteristic. The spectrum was obtained from this matrix and the measured photocurrents at various SPR coupling angles. Light with single and multiple wavelengths was tested. Comparative measurements showed that our method is able to detect spectra with a wavelength resolution comparable to that of a commercial spectrometer.
Testing the Formation Mechanism of Sub-Stellar Objects in Lupus (A SOLA Team Study)
NASA Astrophysics Data System (ADS)
De Gregorio-Monsalvo, Itziar; Lopez, C.; Takahashi, S.; Santamaria-Miranda
2017-06-01
The international SOLA team (Soul of Lupus with ALMA) has identified a set of pre- and proto-stellar candidates in Lupus 1 and 3 of substellar nature using 1.1mm ASTE/AzTEC maps and our optical to submillimeter database. We have observed with ALMA the most promising pre- and proto-brown dwarfs candidates. Our aims are to provide insights on how substellar objects form and evolve, from the equivalent to the pre-stellar cores to the Class II stage in the low mass regime of star formation. Our sample comprises 33 pre-stellar objects, 7 Class 0 and I objects, and 22 Class II objects.
40 CFR 98.433 - Calculating GHG contained in pre-charged equipment or closed-cell foams.
Code of Federal Regulations, 2014 CFR
2014-07-01
...-charged equipment or closed-cell foams. 98.433 Section 98.433 Protection of Environment ENVIRONMENTAL... Exporters of Fluorinated Greenhouse Gases Contained in Pre-Charged Equipment or Closed-Cell Foams § 98.433 Calculating GHG contained in pre-charged equipment or closed-cell foams. (a) The total mass of each...
40 CFR 98.433 - Calculating GHG contained in pre-charged equipment or closed-cell foams.
Code of Federal Regulations, 2013 CFR
2013-07-01
...-charged equipment or closed-cell foams. 98.433 Section 98.433 Protection of Environment ENVIRONMENTAL... Exporters of Fluorinated Greenhouse Gases Contained in Pre-Charged Equipment or Closed-Cell Foams § 98.433 Calculating GHG contained in pre-charged equipment or closed-cell foams. (a) The total mass of each...
40 CFR 98.433 - Calculating GHG contained in pre-charged equipment or closed-cell foams.
Code of Federal Regulations, 2011 CFR
2011-07-01
...-charged equipment or closed-cell foams. 98.433 Section 98.433 Protection of Environment ENVIRONMENTAL... Exporters of Fluorinated Greenhouse Gases Contained in Pre-Charged Equipment or Closed-Cell Foams § 98.433 Calculating GHG contained in pre-charged equipment or closed-cell foams. (a) The total mass of each...
40 CFR 98.433 - Calculating GHG contained in pre-charged equipment or closed-cell foams.
Code of Federal Regulations, 2012 CFR
2012-07-01
...-charged equipment or closed-cell foams. 98.433 Section 98.433 Protection of Environment ENVIRONMENTAL... Exporters of Fluorinated Greenhouse Gases Contained in Pre-Charged Equipment or Closed-Cell Foams § 98.433 Calculating GHG contained in pre-charged equipment or closed-cell foams. (a) The total mass of each...
Library of Giant Planet Reflection Spectra for WFirst and Future Space Telescopes
NASA Astrophysics Data System (ADS)
Smith, Adam J. R. W.; Fortney, Jonathan; Morley, Caroline; Batalha, Natasha E.; Lewis, Nikole K.
2018-01-01
Future large space space telescopes will be able to directly image exoplanets in optical light. The optical light of a resolved planet is due to stellar flux reflected by Rayleigh scattering or cloud scattering, with absorption features imprinted due to molecular bands in the planetary atmosphere. To aid in the design of such missions, and to better understand a wide range of giant planet atmospheres, we have built a library of model giant planet reflection spectra, for the purpose of determining effective methods of spectral analysis as well as for comparison with actual imaged objects. This library covers a wide range of parameters: objects are modeled at ten orbital distances between 0.5 AU and 5.0 AU, which ranges from planets too warm for water clouds, out to those that are true Jupiter analogs. These calculations include six metalicities between solar and 100x solar, with a variety of different cloud thickness parameters, and across all possible phase angles.
Trevors, J T
2012-12-01
The hypothesis is proposed that during the organization of pre-biotic bacterial cell(s), high-energy electrical discharges, infrared radiation (IR), thermosynthesis and possibly pre-photosynthesis were central to the origin of life. High-energy electrical discharges generated some simple organic molecules available for the origin of life. Infrared radiation, both incoming to the Earth and generated on the cooling Earth with day/night and warming/cooling cycles, was a component of heat engine thermosynthesis before enzymes and the genetic code were present. Eventually, a primitive forerunner of photosynthesis and the capability to capture visible light emerged. In addition, the dual particle-wave nature of light is discussed from the perspective that life requires light acting both as a wave and particle.
Brants, Marijke; Bulthé, Jessica; Daniels, Nicky; Wagemans, Johan; Op de Beeck, Hans P
2016-02-15
Visual object perception is an important function in primates which can be fine-tuned by experience, even in adults. Which factors determine the regions and the neurons that are modified by learning is still unclear. Recently, it was proposed that the exact cortical focus and distribution of learning effects might depend upon the pre-learning mapping of relevant functional properties and how this mapping determines the informativeness of neural units for the stimuli and the task to be learned. From this hypothesis we would expect that visual experience would strengthen the pre-learning distributed functional map of the relevant distinctive object properties. Here we present a first test of this prediction in twelve human subjects who were trained in object categorization and differentiation, preceded and followed by a functional magnetic resonance imaging session. Specifically, training increased the distributed multi-voxel pattern information for trained object distinctions in object-selective cortex, resulting in a generalization from pre-training multi-voxel activity patterns to after-training activity patterns. Simulations show that the increased selectivity combined with the inter-session generalization is consistent with a training-induced strengthening of a pre-existing selectivity map. No training-related neural changes were detected in other regions. In sum, training to categorize or individuate objects strengthened pre-existing representations in human object-selective cortex, providing a first indication that the neuroanatomical distribution of learning effects depends upon the pre-learning mapping of visual object properties. Copyright © 2015 Elsevier Inc. All rights reserved.
ERIC Educational Resources Information Center
Suydam, Marilyn, Comp.
This volume reports research conducted to provide the National Science Foundation (NSF) with information concerning the existing range of beliefs and opinions about the impact of the hand-held calculator on pre-college educational practice. A literature search and several surveys of groups of individuals involved in calculator manufacture and…
Anderson, Roy; Farrell, Sam; Turner, Hugo; Walson, Judd; Donnelly, Christl A; Truscott, James
2017-02-17
A method is outlined for the use of an individual-based stochastic model of parasite transmission dynamics to assess different designs for a cluster randomized trial in which mass drug administration (MDA) is employed in attempts to eliminate the transmission of soil-transmitted helminths (STH) in defined geographic locations. The hypothesis to be tested is: Can MDA alone interrupt the transmission of STH species in defined settings? Clustering is at a village level and the choice of clusters of villages is stratified by transmission intensity (low, medium and high) and parasite species mix (either Ascaris, Trichuris or hookworm dominant). The methodological approach first uses an age-structured deterministic model to predict the MDA coverage required for treating pre-school aged children (Pre-SAC), school aged children (SAC) and adults (Adults) to eliminate transmission (crossing the breakpoint in transmission created by sexual mating in dioecious helminths) with 3 rounds of annual MDA. Stochastic individual-based models are then used to calculate the positive and negative predictive values (PPV and NPV, respectively, for observing elimination or the bounce back of infection) for a defined prevalence of infection 2 years post the cessation of MDA. For the arm only involving the treatment of Pre-SAC and SAC, the failure rate is predicted to be very high (particularly for hookworm-infected villages) unless transmission intensity is very low (R 0 , or the effective reproductive number R, just above unity in value). The calculations are designed to consider various trial arms and stratifications; namely, community-based treatment and Pre-SAC and SAC only treatment (the two arms of the trial), different STH transmission settings of low, medium and high, and different STH species mixes. Results are considered in the light of the complications introduced by the choice of statistic to define success or failure, varying adherence to treatment, migration and parameter uncertainty.
Stopping time: Henry Fox Talbot and the origins of freeze-frame photography.
Ramalingam, Chitra
2008-09-01
As an image-making tool for scientists studying the transient, instantaneous photography has long been seen as opening up a visual realm previously inaccessible to the inferior testimony of the human eye. But when photographic pioneer Henry Fox Talbot took the first photograph of a moving object by the light of an electric spark in 1851, he was guided by existing visual practices designed to create instantaneous vision in the eye itself. Exploring the background behind the peculiar subject of his experiment - a mechanically spinning disc - reveals a hidden prehistory of spark-illuminated photography: physicists' pre-photographic techniques for stopping time.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kambersky, V.; Schaefer, R.; Leibniz Institute for Solid State and Materials Research, Helmholtzstrasse 20, 01069 Dresden
2011-07-15
An anomalous symmetry of magneto-optical images of ferromagnetic domain walls was reported by Schaefer and Hubert [Phys. Status Solidi A 118, 271 (1990)] and interpreted in terms of light amplitudes proportional to the magnetization gradient. We present analytic and numerical calculations supporting such proportionality under additional conditions implied by classical rules of micromagnetics and address some objections presented by Banno [Phys. Rev. A 77, 033818 (2008)] against such proportionality.
The stellar wind of an O8.5 I(f) star in M 31
NASA Technical Reports Server (NTRS)
Haser, S. M.; Lennon, D. J.; Kudritzki, R.-P.; Puls, J.; Pauldrach, A. W. A.; Bianchi, L.; Hutchings, J. B.
1995-01-01
We rediscuss the UV spectrum of OB 78#231, an O8.5 I(f) star in the Andromeda galaxy M 31, which has been obtained with the Faint Object Spectrograph on the Hubble Space Telescope by Hutchings et al. (1992). The spectrum has been re-extracted with better knowledge of background, calibration, and scattered light. The empirical analysis of the stellar wind lines results in a terminal velocity and mass loss rate similar to those typically found in comparable galactic objects. Furthermore, a comparison with an FOS spectrum of an O7 supergiant in the Small Magellanic Cloud and IUE spectra of galactic objects implies a metallicity close to galactic counterparts. These results are confirmed quantitatively by spectrum synthesis calculations using a theoretical description of O-star winds.
A numerical experiment on light pollution from distant sources
NASA Astrophysics Data System (ADS)
Kocifaj, M.
2011-08-01
To predict the light pollution of the night-time sky realistically over any location or measuring point on the ground presents quite a difficult calculation task. Light pollution of the local atmosphere is caused by stray light, light loss or reflection of artificially illuminated ground objects or surfaces such as streets, advertisement boards or building interiors. Thus it depends on the size, shape, spatial distribution, radiative pattern and spectral characteristics of many neighbouring light sources. The actual state of the atmospheric environment and the orography of the surrounding terrain are also relevant. All of these factors together influence the spectral sky radiance/luminance in a complex manner. Knowledge of the directional behaviour of light pollution is especially important for the correct interpretation of astronomical observations. From a mathematical point of view, the light noise or veil luminance of a specific sky element is given by a superposition of scattered light beams. Theoretical models that simulate light pollution typically take into account all ground-based light sources, thus imposing great requirements on CPU and MEM. As shown in this paper, a contribution of distant sources to the light pollution might be essential under specific conditions of low turbidity and/or Garstang-like radiative patterns. To evaluate the convergence of the theoretical model, numerical experiments are made for different light sources, spectral bands and atmospheric conditions. It is shown that in the worst case the integration limit is approximately 100 km, but it can be significantly shortened for light sources with cosine-like radiative patterns.
Three-dimensional displacement measurement of image point by point-diffraction interferometry
NASA Astrophysics Data System (ADS)
He, Xiao; Chen, Lingfeng; Meng, Xiaojie; Yu, Lei
2018-01-01
This paper presents a method for measuring the three-dimensional (3-D) displacement of an image point based on point-diffraction interferometry. An object Point-light-source (PLS) interferes with a fixed PLS and its interferograms are captured by an exit pupil. When the image point of the object PLS is slightly shifted to a new position, the wavefront of the image PLS changes. And its interferograms also change. Processing these figures (captured before and after the movement), the wavefront difference of the image PLS can be obtained and it contains the information of three-dimensional (3-D) displacement of the image PLS. However, the information of its three-dimensional (3-D) displacement cannot be calculated until the distance between the image PLS and the exit pupil is calibrated. Therefore, we use a plane-parallel-plate with a known refractive index and thickness to determine this distance, which is based on the Snell's law for small angle of incidence. Thus, since the distance between the exit pupil and the image PLS is a known quantity, the 3-D displacement of the image PLS can be simultaneously calculated through two interference measurements. Preliminary experimental results indicate that its relative error is below 0.3%. With the ability to accurately locate an image point (whatever it is real or virtual), a fiber point-light-source can act as the reticle by itself in optical measurement.
Fuchs, Lynn S.; Gilbert, Jennifer K.; Powell, Sarah R.; Cirino, Paul T.; Fuchs, Douglas; Hamlett, Carol L.; Seethaler, Pamela M.; Tolar, Tammy D.
2016-01-01
The purpose of this study was to examine child-level pathways in development of pre-algebraic knowledge versus word-problem solving, while evaluating the contribution of calculation accuracy and fluency as mediators of foundational skills/processes. Children (n = 962; mean 7.60 years) were assessed on general cognitive processes and early calculation, word-problem, and number knowledge at start of grade 2; calculation accuracy and calculation fluency at end of grade 2; and pre-algebraic knowledge and word-problem solving at end of grade 4. Important similarities in pathways were identified, but path analysis also indicated that language comprehension is more critical for later word-problem solving than pre-algebraic knowledge. We conclude that pathways in development of these forms of 4th-grade mathematics performance are more alike than different, but demonstrate the need to fine-tune instruction for strands of the mathematics curriculum in ways that address individual students’ foundational mathematics skills or cognitive processes. PMID:27786534
Lercari, B; Bertram, L
2004-02-01
The interactions of phytochrome A (phyA), phytochrome B1 (phyB1) and phytochrome B2 (phyB2) in light-dependent shoot regeneration from the hypocotyl of tomato was analysed using all eight possible homozygous allelic combinations of the null mutants. The donor plants were pre-grown either in the dark or under red or far-red light for 8 days after sowing; thereafter hypocotyl segments (apical, middle and basal portions) were transferred onto hormone-free medium for culture under different light qualities. Etiolated apical segments cultured in vitro under white light showed a very high frequency of regeneration for all of the genotypes tested besides phyB1phyB2, phyAphyB1 and phyAphyB1phyB2 mutants. Evidence is provided of a specific interference of phyB2 with phyA-mediated HIR to far-red and blue light in etiolated explants. Pre-treatment of donor plants by growth under red light enhanced the competence of phyB1phyB2, phyAphyB1 and phyAphyB1phyB2 mutants for shoot regeneration, whereas pre-irradiation with far-red light enhanced the frequency of regeneration only in the phyAphyB1 mutant. Multiple phytochromes are involved in red light- and far-red light-dependent acquisition of competence for shoot regeneration. The position of the segments along the hypocotyl influenced the role of the various phytochromes and the interactions between them. The culture of competent hypocotyl segments under red, far-red or blue light reduced the frequency of explants forming shoots compared to those cultured under white light, with different genotypes having different response patterns.
Spectral matching technology for light-emitting diode-based jaundice photodynamic therapy device
NASA Astrophysics Data System (ADS)
Gan, Ru-ting; Guo, Zhen-ning; Lin, Jie-ben
2015-02-01
The objective of this paper is to obtain the spectrum of light-emitting diode (LED)-based jaundice photodynamic therapy device (JPTD), the bilirubin absorption spectrum in vivo was regarded as target spectrum. According to the spectral constructing theory, a simple genetic algorithm as the spectral matching algorithm was first proposed in this study. The optimal combination ratios of LEDs were obtained, and the required LEDs number was then calculated. Meanwhile, the algorithm was compared with the existing spectral matching algorithms. The results show that this algorithm runs faster with higher efficiency, the switching time consumed is 2.06 s, and the fitting spectrum is very similar to the target spectrum with 98.15% matching degree. Thus, blue LED-based JPTD can replace traditional blue fluorescent tube, the spectral matching technology that has been put forward can be applied to the light source spectral matching for jaundice photodynamic therapy and other medical phototherapy.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Falewicz, Robert; Radziszewski, Krzysztof; Rudawy, Paweł
2017-10-01
We compare time variations of the H α and X-ray emissions observed during the pre-impulsive and impulsive phases of the C1.1-class solar flare on 2013 June 21 with those of plasma parameters and synthesized X-ray emission from a 1D hydrodynamic numerical model of the flare. The numerical model was calculated assuming that the external energy is delivered to the flaring loop by nonthermal electrons (NTEs). The H α spectra and images were obtained using the Multi-channel Subtractive Double Pass spectrograph with a time resolution of 50 ms. The X-ray fluxes and spectra were recorded by RHESSI . Pre-flare geometric andmore » thermodynamic parameters of the model and the delivered energy were estimated using RHESSI data. The time variations of the X-ray light curves in various energy bands and those of the H α intensities and line profiles were well correlated. The timescales of the observed variations agree with the calculated variations of the plasma parameters in the flaring loop footpoints, reflecting the time variations of the vertical extent of the energy deposition layer. Our result shows that the fast time variations of the H α emission of the flaring kernels can be explained by momentary changes of the deposited energy flux and the variations of the penetration depths of the NTEs.« less
Including robustness in multi-criteria optimization for intensity-modulated proton therapy
NASA Astrophysics Data System (ADS)
Chen, Wei; Unkelbach, Jan; Trofimov, Alexei; Madden, Thomas; Kooy, Hanne; Bortfeld, Thomas; Craft, David
2012-02-01
We present a method to include robustness in a multi-criteria optimization (MCO) framework for intensity-modulated proton therapy (IMPT). The approach allows one to simultaneously explore the trade-off between different objectives as well as the trade-off between robustness and nominal plan quality. In MCO, a database of plans each emphasizing different treatment planning objectives, is pre-computed to approximate the Pareto surface. An IMPT treatment plan that strikes the best balance between the different objectives can be selected by navigating on the Pareto surface. In our approach, robustness is integrated into MCO by adding robustified objectives and constraints to the MCO problem. Uncertainties (or errors) of the robust problem are modeled by pre-calculated dose-influence matrices for a nominal scenario and a number of pre-defined error scenarios (shifted patient positions, proton beam undershoot and overshoot). Objectives and constraints can be defined for the nominal scenario, thus characterizing nominal plan quality. A robustified objective represents the worst objective function value that can be realized for any of the error scenarios and thus provides a measure of plan robustness. The optimization method is based on a linear projection solver and is capable of handling large problem sizes resulting from a fine dose grid resolution, many scenarios, and a large number of proton pencil beams. A base-of-skull case is used to demonstrate the robust optimization method. It is demonstrated that the robust optimization method reduces the sensitivity of the treatment plan to setup and range errors to a degree that is not achieved by a safety margin approach. A chordoma case is analyzed in more detail to demonstrate the involved trade-offs between target underdose and brainstem sparing as well as robustness and nominal plan quality. The latter illustrates the advantage of MCO in the context of robust planning. For all cases examined, the robust optimization for each Pareto optimal plan takes less than 5 min on a standard computer, making a computationally friendly interface possible to the planner. In conclusion, the uncertainty pertinent to the IMPT procedure can be reduced during treatment planning by optimizing plans that emphasize different treatment objectives, including robustness, and then interactively seeking for a most-preferred one from the solution Pareto surface.
40 CFR 85.525 - Applicable standards.
Code of Federal Regulations, 2014 CFR
2014-07-01
... on FTP test results from the emission data vehicle (EDV) representing the pre-conversion test group. The sum of CO2, CH4, and N2O shall be calculated for pre- and post-conversion FTP test results, where... group. The sum of CO2, CH4, and N2O shall be calculated for pre- and post-conversion FTP test results...
Mitchnick, Krista A; Wideman, Cassidy E; Huff, Andrew E; Palmer, Daniel; McNaughton, Bruce L; Winters, Boyer D
2018-05-15
The capacity to recognize objects from different view-points or angles, referred to as view-invariance, is an essential process that humans engage in daily. Currently, the ability to investigate the neurobiological underpinnings of this phenomenon is limited, as few ethologically valid view-invariant object recognition tasks exist for rodents. Here, we report two complementary, novel view-invariant object recognition tasks in which rodents physically interact with three-dimensional objects. Prior to experimentation, rats and mice were given extensive experience with a set of 'pre-exposure' objects. In a variant of the spontaneous object recognition task, novelty preference for pre-exposed or new objects was assessed at various angles of rotation (45°, 90° or 180°); unlike control rodents, for whom the objects were novel, rats and mice tested with pre-exposed objects did not discriminate between rotated and un-rotated objects in the choice phase, indicating substantial view-invariant object recognition. Secondly, using automated operant touchscreen chambers, rats were tested on pre-exposed or novel objects in a pairwise discrimination task, where the rewarded stimulus (S+) was rotated (180°) once rats had reached acquisition criterion; rats tested with pre-exposed objects re-acquired the pairwise discrimination following S+ rotation more effectively than those tested with new objects. Systemic scopolamine impaired performance on both tasks, suggesting involvement of acetylcholine at muscarinic receptors in view-invariant object processing. These tasks present novel means of studying the behavioral and neural bases of view-invariant object recognition in rodents. Copyright © 2018 Elsevier B.V. All rights reserved.
Lattice QCD Calculation of Hadronic Light-by-Light Scattering.
Green, Jeremy; Gryniuk, Oleksii; von Hippel, Georg; Meyer, Harvey B; Pascalutsa, Vladimir
2015-11-27
We perform a lattice QCD calculation of the hadronic light-by-light scattering amplitude in a broad kinematical range. At forward kinematics, the results are compared to a phenomenological analysis based on dispersive sum rules for light-by-light scattering. The size of the pion pole contribution is investigated for momenta of typical hadronic size. The presented numerical methods can be used to compute the hadronic light-by-light contribution to the anomalous magnetic moment of the muon. Our calculations are carried out in two-flavor QCD with the pion mass in the range of 270-450 MeV and contain so far only the diagrams with fully connected quark lines.
Digital camera auto white balance based on color temperature estimation clustering
NASA Astrophysics Data System (ADS)
Zhang, Lei; Liu, Peng; Liu, Yuling; Yu, Feihong
2010-11-01
Auto white balance (AWB) is an important technique for digital cameras. Human vision system has the ability to recognize the original color of an object in a scene illuminated by a light source that has a different color temperature from D65-the standard sun light. However, recorded images or video clips, can only record the original information incident into the sensor. Therefore, those recorded will appear different from the real scene observed by the human. Auto white balance is a technique to solve this problem. Traditional methods such as gray world assumption, white point estimation, may fail for scenes with large color patches. In this paper, an AWB method based on color temperature estimation clustering is presented and discussed. First, the method gives a list of several lighting conditions that are common for daily life, which are represented by their color temperatures, and thresholds for each color temperature to determine whether a light source is this kind of illumination; second, an image to be white balanced are divided into N blocks (N is determined empirically). For each block, the gray world assumption method is used to calculate the color cast, which can be used to estimate the color temperature of that block. Third, each calculated color temperature are compared with the color temperatures in the given illumination list. If the color temperature of a block is not within any of the thresholds in the given list, that block is discarded. Fourth, the remaining blocks are given a majority selection, the color temperature having the most blocks are considered as the color temperature of the light source. Experimental results show that the proposed method works well for most commonly used light sources. The color casts are removed and the final images look natural.
Comparison of the Light Charged Particles on Scatter Radiation Dose in Thyroid Hadron Therapy
Azizi, M; Mowlavi, AA
2014-01-01
Background: Hadron therapy is a novel technique of cancer radiation therapy which employs charged particles beams, 1H and light ions in particular. Due to their physical and radiobiological properties, they allow one to obtain a more conformal treatment, sparing better the healthy tissues located in proximity of the tumor and allowing a higher control of the disease. Objective: As it is well known, these light particles can interact with nuclei in the tissue, and produce the different secondary particles such as neutron and photon. These particles can damage specially the critical organs behind of thyroid gland. Methods: In this research, we simulated neck geometry by MCNPX code and calculated the light particles dose at distance of 2.14 cm in thyroid gland, for different particles beam: 1H, 2H, 3He, and 4He. Thyroid treatment is important because the spine and vertebrae is situated right behind to the thyroid gland on the posterior side. Results: The results show that 2H has the most total flux for photon and neutron, 1.944E-3 and 1.7666E-2, respectively. Whereas 1H and 3He have best conditions, 8.88609E-4 and 1.35431E-3 for photon, 4.90506E-4 and 4.34057E-3 for neutron, respectively. The same calculation has obtained for energy depositions for these particles. Conclusion: In this research, we investigated that which of these light particles can deliver the maximum dose to the normal tissues and the minimum dose to the tumor. By comparing these results for the mentioned light particles, we find out 1H and 3He is the best therapy choices for thyroid glands whereas 2H is the worst. PMID:25505774
Selected Topics in Light Front Field Theory and Applications to the High Energy Phenomena
NASA Astrophysics Data System (ADS)
Kundu, Rajen
1999-10-01
In this thesis, we have presented some of the aspects of light-front (LF) field theory through their successful application in the Deep Inelastic Scattering (DIS). We have developed a LFQCD Hamiltonian description of the DIS structure functions starting from Bjorken-Johnson-Low limit of virtual forward Compton scattering amplitude and using LF current commutators. We worked in the LF gauge A^+=0 and used the old-fashioned LFQCD perturbation theory in our calculations. The importance of our work are summarized below. Our approach shares the intution of parton model and addresses directly the structure functions, which are experimental objects, instead of its moments as in OPE method. Moreover, it can potentially incorporate the non-perturbative contents of the structure functions as we have demonstrated by introducing a new factorization scheme. In the context of nucleonic helicity structure, the well known gauge fixed LF helicity operator is shown to provide consistent physical information and helps us defining new relevant structure functions. The anomalous dimensions relevant for the Q^2-evolution of such structure functions are calculated. Our study is important in establishing the equivalance of LF field theory and the usual equal-time one through perturbative calculations of the dressed parton structure functions reproducing the well known results. Also the importance of Gallilean boost symmetry in understanding the correctness of any higher order calculation using (x^+)-ordered LFQCD perturbation theory are emphasized.
Mass-energy distribution of fragments within Langevin dynamics of fission induced by heavy ions
NASA Astrophysics Data System (ADS)
Anischenko, Yu. A.; Adeev, G. D.
2012-08-01
A stochastic approach based on four-dimensional Langevin fission dynamics is applied to calculating mass-energy distributions of fragments originating from the fission of excited compound nuclei. In the model under investigation, the coordinate K representing the projection of the total angular momentum onto the symmetry axis of the nucleus is taken into account in addition to three collective shape coordinates introduced on the basis of the { c, h, α} parametrization. The evolution of the orientation degree of freedom ( K mode) is described by means of the Langevin equation in the overdamped regime. The tensor of friction is calculated under the assumption of the reducedmechanismof one-body dissipation in the wall-plus-window model. The calculations are performed for two values of the coefficient that takes into account the reduction of the contribution from the wall formula: k s = 0.25 and k s = 1.0. Calculations with a modified wall-plus-window formula are also performed, and the quantity measuring the degree to which the single-particle motion of nucleons within the nuclear system being considered is chaotic is used for k s in this calculation. Fusion-fission reactions leading to the production of compound nuclei are considered for values of the parameter Z 2/ A in the range between 21 and 44. So wide a range is chosen in order to perform a comparative analysis not only for heavy but also for light compound nuclei in the vicinity of the Businaro-Gallone point. For all of the reactions considered in the present study, the calculations performed within four-dimensional Langevin dynamics faithfully reproduce mass-energy and mass distributions obtained experimentally. The inclusion of the K mode in the Langevin equation leads to an increase in the variances of mass and energy distributions in relation to what one obtains from three-dimensional Langevin calculations. The results of the calculations where one associates k s with the measure of chaoticity in the single-particle motion of nucleons within the nuclear system under study are in good agreement for variances of mass distributions. The results of calculations for the correlations between the prescission neutron multiplicity and the fission-fragment mass, < n pre( M)>, and between, this multiplicity and the kinetic energy of fission fragments, < n pre( E k )>, are also presented.
NASA Astrophysics Data System (ADS)
Xu, Jinghai; An, Jiwen; Nie, Gaozong
2016-04-01
Improving earthquake disaster loss estimation speed and accuracy is one of the key factors in effective earthquake response and rescue. The presentation of exposure data by applying a dasymetric map approach has good potential for addressing this issue. With the support of 30'' × 30'' areal exposure data (population and building data in China), this paper presents a new earthquake disaster loss estimation method for emergency response situations. This method has two phases: a pre-earthquake phase and a co-earthquake phase. In the pre-earthquake phase, we pre-calculate the earthquake loss related to different seismic intensities and store them in a 30'' × 30'' grid format, which has several stages: determining the earthquake loss calculation factor, gridding damage probability matrices, calculating building damage and calculating human losses. Then, in the co-earthquake phase, there are two stages of estimating loss: generating a theoretical isoseismal map to depict the spatial distribution of the seismic intensity field; then, using the seismic intensity field to extract statistics of losses from the pre-calculated estimation data. Thus, the final loss estimation results are obtained. The method is validated by four actual earthquakes that occurred in China. The method not only significantly improves the speed and accuracy of loss estimation but also provides the spatial distribution of the losses, which will be effective in aiding earthquake emergency response and rescue. Additionally, related pre-calculated earthquake loss estimation data in China could serve to provide disaster risk analysis before earthquakes occur. Currently, the pre-calculated loss estimation data and the two-phase estimation method are used by the China Earthquake Administration.
An evaluation of shear bond strength of self-etch adhesive on pre-etched enamel: an in vitro study.
Rao, Bhadra; Reddy, Satti Narayana; Mujeeb, Abdul; Mehta, Kanchan; Saritha, G
2013-11-01
To determine the shear bond strength of self-etch adhesive G-bond on pre-etched enamel. Thirty caries free human mandibular premolars extracted for orthodontic purpose were used for the study. Occlusal surfaces of all the teeth were flattened with diamond bur and a silicon carbide paper was used for surface smoothening. The thirty samples were randomly grouped into three groups. Three different etch systems were used for the composite build up: group 1 (G-bond self-etch adhesive system), group 2 (G-bond) and group 3 (Adper single bond). Light cured was applied for 10 seconds with a LED unit for composite buildup on the occlusal surface of each tooth with 8 millimeters (mm) in diameter and 3 mm in thickness. The specimens in each group were tested in shear mode using a knife-edge testing apparatus in a universal testing machine across head speed of 1 mm/ minute. Shear bond strength values in Mpa were calculated from the peak load at failure divided by the specimen surface area. The mean shear bond strength of all the groups were calculated and statistical analysis was carried out using one-way Analysis of Variance (ANOVA). The mean bond strength of group 1 is 15.5 Mpa, group 2 is 19.5 Mpa and group 3 is 20.1 Mpa. Statistical analysis was carried out between the groups using one-way ANOVA. Group 1 showed statistically significant lower bond strength when compared to groups 2 and 3. No statistical significant difference between groups 2 and 3 (p < 0.05). Self-etch adhesive G-bond showed increase in shear bond strength on pre-etched enamel.
Lewis, L K; Rowlands, A V; Gardiner, P A; Standage, M; English, C; Olds, T
2016-03-01
This study aimed to evaluate the preliminary effectiveness and feasibility of a theory-informed program to reduce sitting time in older adults. Pre-experimental (pre-post) study. Thirty non-working adult (≥ 60 years) participants attended a one hour face-to-face intervention session and were guided through: a review of their sitting time; normative feedback on sitting time; and setting goals to reduce total sitting time and bouts of prolonged sitting. Participants chose six goals and integrated one per week incrementally for six weeks. Participants received weekly phone calls. Sitting time and bouts of prolonged sitting (≥ 30 min) were measured objectively for seven days (activPAL3c inclinometer) pre- and post-intervention. During these periods, a 24-h time recall instrument was administered by computer-assisted telephone interview. Participants completed a post-intervention project evaluation questionnaire. Paired t tests with sequential Bonferroni corrections and Cohen's d effect sizes were calculated for all outcomes. Twenty-seven participants completed the assessments (71.7 ± 6.5 years). Post-intervention, objectively-measured total sitting time was significantly reduced by 51.5 min per day (p=0.006; d=-0.58) and number of bouts of prolonged sitting by 0.8 per day (p=0.002; d=-0.70). Objectively-measured standing increased by 39 min per day (p=0.006; d=0.58). Participants self-reported spending 96 min less per day sitting (p<0.001; d=-0.77) and 32 min less per day watching television (p=0.005; d=-0.59). Participants were highly satisfied with the program. The 'Small Steps' program is a feasible and promising avenue for behavioral modification to reduce sitting time in older adults. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Improved Ecosystem Predictions of the California Current System via Accurate Light Calculations
2011-09-30
System via Accurate Light Calculations Curtis D. Mobley Sequoia Scientific, Inc. 2700 Richards Road, Suite 107 Bellevue, WA 98005 phone: 425...7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Sequoia Scientific, Inc,2700 Richards Road, Suite 107,Bellevue,WA,98005 8. PERFORMING...EcoLight-S 1.0 Users’ Guide and Technical Documentation. Sequoia Scientific, Inc., Bellevue, WA, 38 pages. Mobley, C. D., 2011. Fast light calculations
Self-recalibration of a robot-assisted structured-light-based measurement system.
Xu, Jing; Chen, Rui; Liu, Shuntao; Guan, Yong
2017-11-10
The structured-light-based measurement method is widely employed in numerous fields. However, for industrial inspection, to achieve complete scanning of a work piece and overcome occlusion, the measurement system needs to be moved to different viewpoints. Moreover, frequent reconfiguration of the measurement system may be needed based on the size of the measured object, making the self-recalibration of extrinsic parameters indispensable. To this end, this paper proposes an automatic self-recalibration and reconstruction method, wherein a robot arm is employed to move the measurement system for complete scanning; the self-recalibration is achieved using fundamental matrix calculations and point cloud registration without the need for an accurate calibration gauge. Experimental results demonstrate the feasibility and accuracy of our method.
Underwater image enhancement through depth estimation based on random forest
NASA Astrophysics Data System (ADS)
Tai, Shen-Chuan; Tsai, Ting-Chou; Huang, Jyun-Han
2017-11-01
Light absorption and scattering in underwater environments can result in low-contrast images with a distinct color cast. This paper proposes a systematic framework for the enhancement of underwater images. Light transmission is estimated using the random forest algorithm. RGB values, luminance, color difference, blurriness, and the dark channel are treated as features in training and estimation. Transmission is calculated using an ensemble machine learning algorithm to deal with a variety of conditions encountered in underwater environments. A color compensation and contrast enhancement algorithm based on depth information was also developed with the aim of improving the visual quality of underwater images. Experimental results demonstrate that the proposed scheme outperforms existing methods with regard to subjective visual quality as well as objective measurements.
Interferometer Control of Optical Tweezers
NASA Technical Reports Server (NTRS)
Decker, Arthur J.
2002-01-01
This paper discusses progress in using spatial light modulators and interferometry to control the beam profile of an optical tweezers. The approach being developed is to use a spatial light modulator (SLM) to control the phase profile of the tweezers beam and to use a combination of the SLM and interferometry to control the intensity profile. The objective is to perform fine and calculable control of the moments and forces on a tip or tool to be used to manipulate and interrogate nanostructures. The performance of the SLM in generating multiple and independently controllable tweezers beams is also reported. Concurrent supporting research projects are mentioned and include tweezers beam scattering and neural-net processing of the interference patterns for control of the tweezers beams.
Simulation of laser beam reflection at the sea surface modeling and validation
NASA Astrophysics Data System (ADS)
Schwenger, Frédéric; Repasi, Endre
2013-06-01
A 3D simulation of the reflection of a Gaussian shaped laser beam on the dynamic sea surface is presented. The simulation is suitable for the pre-calculation of images for cameras operating in different spectral wavebands (visible, short wave infrared) for a bistatic configuration of laser source and receiver for different atmospheric conditions. In the visible waveband the calculated detected total power of reflected laser light from a 660nm laser source is compared with data collected in a field trial. Our computer simulation comprises the 3D simulation of a maritime scene (open sea/clear sky) and the simulation of laser beam reflected at the sea surface. The basic sea surface geometry is modeled by a composition of smooth wind driven gravity waves. To predict the view of a camera the sea surface radiance must be calculated for the specific waveband. Additionally, the radiances of laser light specularly reflected at the wind-roughened sea surface are modeled considering an analytical statistical sea surface BRDF (bidirectional reflectance distribution function). Validation of simulation results is prerequisite before applying the computer simulation to maritime laser applications. For validation purposes data (images and meteorological data) were selected from field measurements, using a 660nm cw-laser diode to produce laser beam reflection at the water surface and recording images by a TV camera. The validation is done by numerical comparison of measured total laser power extracted from recorded images with the corresponding simulation results. The results of the comparison are presented for different incident (zenith/azimuth) angles of the laser beam.
Smirnakou, Sonia; Ouzounis, Theoharis; Radoglou, Kalliopi M.
2017-01-01
Regulation of the growth, development, and quality of plants by the control of light quality has attracted extensive attention worldwide. The aim of this study was to examine the effects of continuous LED spectrum for indoor plant pre-cultivation and to investigate the morphological and physiological responses of a common broadleaved tree species in Mediterranean environment, Quercus ithaburensis var. macrolepis at seedling developmental stage. Thus, the seedlings were pre-cultivated for 28 days, under five different LED light qualities: (1) Fluorescent (FL) as control light (2) L20AP67 (high in green and moderate in far-red), (3) AP673L (high in green and red), (4) G2 (highest in red and far-red), AP67 (high in blue, red, and far-red), and (5) NS1 (highest in blue and green and lowest in far-red) LEDs. Further examination was held at the nursery for 1 year, on several seedling quality traits. Indeed, AP67 and AP673L triggered higher leaf formation, while L20AP67 positively affected seedling shoot development. NS1 and AP67 LED pre-cultivated seedlings showed significantly higher root fibrosity than those of FL light. Furthermore, NS1 and AP673L LEDs induced fourfold increase on seedling root dry weight than FL light. Hence, evaluating the seedling nursery performance attributes, most of those photomorphogenetic responses previously obtained were still detectable. Even more so, LED pre-cultivated seedlings showed higher survival and faster growth indicating better adaptation even under natural light conditions, a fact further reinforced by the significantly higher Dickson’s quality index acquired. In conclusion, the goal of each nursery management program is the production of high quality seedlings with those desirable traits, which in turn satisfy the specific needs for a particular reforestation site. Thus, the enhanced oak seedling quality traits formed under continuous LEDs spectrum especially of NS1 and AP673L pre-cultivation may potentially fulfill this goal. PMID:28261244
Testing and modeling of PBX-9591 shock initiation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lam, Kim; Foley, Timothy; Novak, Alan
2010-01-01
This paper describes an ongoing effort to develop a detonation sensitivity test for PBX-9501 that is suitable for studying pristine and damaged HE. The approach involves testing and comparing the sensitivities of HE pressed to various densities and those of pre-damaged samples with similar porosities. The ultimate objectives are to understand the response of pre-damaged HE to shock impacts and to develop practical computational models for use in system analysis codes for HE safety studies. Computer simulation with the CTH shock physics code is used to aid the experimental design and analyze the test results. In the calculations, initiation andmore » growth or failure of detonation are modeled with the empirical HVRB model. The historical LANL SSGT and LSGT were reviewed and it was determined that a new, modified gap test be developed to satisfy the current requirements. In the new test, the donor/spacer/acceptor assembly is placed in a holder that is designed to work with fixtures for pre-damaging the acceptor sample. CTH simulations were made of the gap test with PBX-9501 samples pressed to three different densities. The calculated sensitivities were validated by test observations. The agreement between the computed and experimental critical gap thicknesses, ranging from 9 to 21 mm under various test conditions, is well within 1 mm. These results show that the numerical modeling is a valuable complement to the experimental efforts in studying and understanding shock initiation of PBX-9501.« less
In-Vacuum Photogrammetry of a 10-Meter Solar Sail
NASA Technical Reports Server (NTRS)
Meyer, Chris G.; Jones, Thomas W.; Lunsford, Charles B.; Pappa, Richard S.
2005-01-01
In July 2004, a 10-meter solar sail structure developed by L Garde, Inc. was tested in vacuum at the NASA Glenn 30-meter Plum Brook Space Power Facility in Sandusky, Ohio. The three main objections of the test were to demonstrate unattended deployment from a stowed configuration, to measure the deployed shape of the sail at both ambient and cryogenic room temperatures, and to measure the deployed structural dynamic characteristics (vibration modes). This paper summarizes the work conducted to fulfill the second test objective. The deployed shape was measured photogrammetrically in vacuum conditions with four 2-megapixel digital video cameras contained in custom made pressurized canisters. The canisters included high-intensity LED ring lights to illuminate a grid of retroreflective targets distributed on the solar sail. The test results closely matched pre-test photogrammetry numerical simulations and compare well with ABAQUS finite-element model predictions.
NASA Technical Reports Server (NTRS)
Irvine, William M.; Schloerb, F. Peter
1997-01-01
The basic theme of this program is the study of molecular complexity and evolution in interstellar clouds and in primitive solar system objects. Research has included the detection and study of a number of new interstellar molecules and investigation of reaction pathways for astrochemistry from a comparison of theory and observed molecular abundances. The latter includes studies of cold, dark clouds in which ion-molecule chemistry should predominate, searches for the effects of interchange of material between the gas and solid phases in interstellar clouds, unbiased spectral surveys of particular sources, and systematic investigation of the interlinked chemistry and physics of dense interstellar clouds. In addition, the study of comets has allowed a comparison between the chemistry of such minimally thermally processed objects and that of interstellar clouds, shedding light on the evolution of the biogenic elements during the process of solar system formation.
Optical device for measuring a surface characteristic of an object by multi-color interferometry
NASA Technical Reports Server (NTRS)
Meyer, William V. (Inventor); Smart, Anthony E. (Inventor)
2001-01-01
An interferometer having a light beam source that produces a plurality of separate and distinct wavelengths of light. Optic fibers are used to transport the wavelengths of light toward an object surface and to allow light reflected from the object to pass through a polarizer to improve the polarization ratio of the reflected light to determine a characteristic of the object surface.
Color-rendering indices in global illumination methods
NASA Astrophysics Data System (ADS)
Geisler-Moroder, David; Dür, Arne
2009-10-01
Human perception of material colors depends heavily on the nature of the light sources that are used for illumination. One and the same object can cause highly different color impressions when lit by a vapor lamp or by daylight, respectively. On the basis of state-of-the-art colorimetric methods, we present a modern approach for the calculation of color-rendering indices (CRI), which were defined by the International Commission on Illumination (CIE) to characterize color reproduction properties of illuminants. We update the standard CIE method in three main points: first, we use the CIELAB color space; second, we apply a linearized Bradford transformation for chromatic adaptation; and finally, we evaluate color differences using the CIEDE2000 total color difference formula. Moreover, within a real-world scene, light incident on a measurement surface is composed of a direct and an indirect part. Neumann and Schanda [Proc. CGIV'06 Conf., Leeds, UK, pp. 283-286 (2006)] have shown for the cube model that diffuse interreflections can influence the CRI of a light source. We analyze how color-rendering indices vary in a real-world scene with mixed direct and indirect illumination and recommend the usage of a spectral rendering engine instead of an RGB-based renderer for reasons of accuracy of CRI calculations.
DOE Office of Scientific and Technical Information (OSTI.GOV)
L.M. Montierth
2000-09-15
The objective of this calculation is to characterize the nuclear criticality safety concerns associated with the codisposal of the U.S. Department of Energy's (DOE) Shippingport Light Water Breeder Reactor (SP LWBR) Spent Nuclear Fuel (SNF) in a 5-Defense High-Level Waste (5-DHLW) Waste Package (WP), which is to be placed in a Monitored Geologic Repository (MGR). The scope of this calculation is limited to the determination of the effective neutron multiplication factor (K{sub eff}) for intact- and degraded-mode internal configurations of the codisposal WP containing Shippingport LWBR seed-type assemblies. The results of this calculation will be used to evaluate criticality issuesmore » and support the analysis that is planed to be performed to demonstrate the viability of the codisposal concept for the MGR. This calculation is associated with the waste package design and was performed in accordance with the DOE SNF Analysis Plan for FY 2000 (See Ref. 22). The document has been prepared in accordance with the Administrative Procedure AP-3.12Q, Calculations (Ref. 23).« less
Lyman-α Emission from an Infant Black Hole in the Early Universe
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wiggins, Brandon Kerry; Smidt, Joseph Michael; Johnson, Jarrett L.
The COSMOS survey recently discovered an exotic young galaxy, COSMOS Redshift 7 (CR7), in the early universe (1 billion years after the Big Bang), which is devoid of evidence of elements heavier than hydrogen and helium. Whereas some believe this might be the first galaxy discovered with stars made only from these elements, others think CR7 may be powered by a newborn supermassive black hole. In this paper, we summarize for a general academic audience our efforts to model the creation of this galaxy through cosmological simulations. These state-of-the-art calculations include primordial chemistry and cooling and the interaction of x-raysmore » from the black hole with surrounding gas. We simulate the process of light escaping this object with Monte Carlo Lyman-α transfer and compare our calculations with observations of CR7. Our work demonstrates the viability of the black hole interpretation for this intriguing object in the early universe.« less
Lyman-α Emission from an Infant Black Hole in the Early Universe
Wiggins, Brandon Kerry; Smidt, Joseph Michael; Johnson, Jarrett L.
2016-01-01
The COSMOS survey recently discovered an exotic young galaxy, COSMOS Redshift 7 (CR7), in the early universe (1 billion years after the Big Bang), which is devoid of evidence of elements heavier than hydrogen and helium. Whereas some believe this might be the first galaxy discovered with stars made only from these elements, others think CR7 may be powered by a newborn supermassive black hole. In this paper, we summarize for a general academic audience our efforts to model the creation of this galaxy through cosmological simulations. These state-of-the-art calculations include primordial chemistry and cooling and the interaction of x-raysmore » from the black hole with surrounding gas. We simulate the process of light escaping this object with Monte Carlo Lyman-α transfer and compare our calculations with observations of CR7. Our work demonstrates the viability of the black hole interpretation for this intriguing object in the early universe.« less
NASA Astrophysics Data System (ADS)
Jeřábková, T.; Kroupa, P.; Dabringhausen, J.; Hilker, M.; Bekki, K.
2017-12-01
The stellar initial mass function (IMF) has been described as being invariant, bottom-heavy, or top-heavy in extremely dense star-burst conditions. To provide usable observable diagnostics, we calculate redshift dependent spectral energy distributions of stellar populations in extreme star-burst clusters, which are likely to have been the precursors of present day massive globular clusters (GCs) and of ultra compact dwarf galaxies (UCDs). The retention fraction of stellar remnants is taken into account to assess the mass to light ratios of the ageing star-burst. Their redshift dependent photometric properties are calculated as predictions for James Webb Space Telescope (JWST) observations. While the present day GCs and UCDs are largely degenerate concerning bottom-heavy or top-heavy IMFs, a metallicity- and density-dependent top-heavy IMF implies the most massive UCDs, at ages < 100 Myr, to appear as objects with quasar-like luminosities with a 0.1-10% variability on a monthly timescale due to core collapse supernovae.
NASA Astrophysics Data System (ADS)
Wyatt, Philip
2009-03-01
The electromagnetic inverse scattering problem suggests that if a homogeneous and non-absorbing object be illuminated with a monochromatic light source and if the far field scattered light intensity is known at sufficient scattering angles, then, in principle, one could derive the dielectric structure of the scattering object. In general, this is an ill-posed problem and methods must be developed to regularize the search for unique solutions. An iterative procedure often begins with a model of the scattering object, solves the forward scattering problem using this model, and then compares these calculated results with the measured values. Key to any such solution is instrumentation capable of providing adequate data. To this end, the development of the first laser based absolute light scattering photometers is described together with their continuing evolution and some of the remarkable discoveries made with them. For particles much smaller than the wavelength of the incident light (e.g. macromolecules), the inverse scattering problems are easily solved. Among the many solutions derived with this instrumentation are the in situ structure of bacterial cells, new drug delivery mechanisms, the development of new vaccines and other biologicals, characterization of wines, the possibility of custom chemotherapy, development of new polymeric materials, identification of protein crystallization conditions, and a variety discoveries concerning protein interactions. A new form of the problem is described to address bioterrorist threats. Over the many years of development and refinement, one element stands out as essential for the successes that followed: the R and D teams were always directed and executed by physics trained theorists and experimentalists. 14 Ph. D. physicists each made his/her unique contribution to the development of these evolving instruments and the interpretation of their results.
Quantitative locomotion study of freely swimming micro-organisms using laser diffraction.
Magnes, Jenny; Susman, Kathleen; Eells, Rebecca
2012-10-25
Soil and aquatic microscopic organisms live and behave in a complex three-dimensional environment. Most studies of microscopic organism behavior, in contrast, have been conducted using microscope-based approaches, which limit the movement and behavior to a narrow, nearly two-dimensional focal field.(1) We present a novel analytical approach that provides real-time analysis of freely swimming C. elegans in a cuvette without dependence on microscope-based equipment. This approach consists of tracking the temporal periodicity of diffraction patterns generated by directing laser light through the cuvette. We measure oscillation frequencies for freely swimming nematodes. Analysis of the far-field diffraction patterns reveals clues about the waveforms of the nematodes. Diffraction is the process of light bending around an object. In this case light is diffracted by the organisms. The light waves interfere and can form a diffraction pattern. A far-field, or Fraunhofer, diffraction pattern is formed if the screen-to-object distance is much larger than the diffracting object. In this case, the diffraction pattern can be calculated (modeled) using a Fourier transform.(2) C. elegans are free-living soil-dwelling nematodes that navigate in three dimensions. They move both on a solid matrix like soil or agar in a sinusoidal locomotory pattern called crawling and in liquid in a different pattern called swimming.(3) The roles played by sensory information provided by mechanosensory, chemosensory, and thermosensory cells that govern plastic changes in locomotory patterns and switches in patterns are only beginning to be elucidated.(4) We describe an optical approach to measuring nematode locomotion in three dimensions that does not require a microscope and will enable us to begin to explore the complexities of nematode locomotion under different conditions.
40 CFR 85.525 - Applicable standards.
Code of Federal Regulations, 2013 CFR
2013-07-01
... results from the emission data vehicle (EDV) representing the pre-conversion test group. The sum of CO2, CH4, and N2O shall be calculated for pre- and post-conversion FTP test results, where CH4 and N2O are..., and N2O shall be calculated for pre- and post-conversion FTP test results, where CH4 and N2O are...
Rasool, Brwa; Karpinska, Barbara; Konert, Grzegorz; Durian, Guido; Denessiouk, Konstantin; Kangasjärvi, Saijaliisa; Foyer, Christine H.
2014-01-01
The interactions between biotic and abiotic stress signaling pathways are complex and poorly understood but protein kinase/phosphatase cascades are potentially important components. Aphid fecundity and susceptibility to Pseudomonas syringae infection were determined in the low light-grown Arabidopsis thaliana wild type and in mutant lines defective in either the protein phosphatase (PP)2A regulatory subunit B'γ (gamma; pp2a-b'γ) or B'ζ (zeta; pp2a-b'ζ1-1 and pp2a-b'ζ 1-2) and in gamma zeta double mutants (pp2a-b'γζ) lacking both subunits. All the mutants except for pp2a-b'ζ 1-1 had significantly lower leaf areas than the wild type. Susceptibility to P. syringae was similar in all genotypes. In contrast, aphid fecundity was significantly decreased in the pp2a-b'γ mutant relative to the wild type but not in the pp2a-b'γζ double mutant. A high light pre-treatment, which led to a significant increase in rosette growth in all mutant lines but not in the wild type, led to a significant decrease in aphid fecundity in all genotypes. The high light pre-treatment abolished the differences in aphid resistance observed in the pp2a-b'γ mutant relative to the wild type. The light and CO2 response curves for photosynthesis were changed in response to the high light pre-treatment, but the high light effects were similar in all genotypes. These data demonstrate that a pre-exposure to high light and the composition of B-subunits on the trimeric PP2A holoenzymes are important in regulating plant resistance to aphids. The functional specificity for the individual regulatory B-subunits may therefore limit aphid colonization, depending on the prevailing abiotic stress environment. PMID:25191331
Turning on the Lights: What Pre-Assessments Can Do
ERIC Educational Resources Information Center
Hockett, Jessica A.; Doubet, Kristina J.
2014-01-01
Pre-assessment has a bad reputation, write Hockett and Doubet--but that's largely because it's often misused solely to compare pre- and post-results. Used this way, pre-assessment serves as little more than a thief of instruction and a discouraging exercise for students. The authors describe how teachers can design thoughtful…
NASA Technical Reports Server (NTRS)
Capuano, J. M., Jr.; Thronson, H. A., Jr.; Witt, A. N.
1993-01-01
The presence of substantial amounts of interstellar dust in late-type galaxies affects observable parameters such as the optical surface brightness, the color, and the ratio of far-infrared to optical luminosity of these galaxies. We conducted radiative transfer calculations for late-type galaxy environments to examine two different scenarios: (1) the effects of increasing amounts of dust in two fixed geometries with different star distributions; and (2) the effects of an evolving dust-star geometry in which the total amount of dust is held constant, for three different star distributions. The calculations were done for ten photometric bands, ranging from the far-ultraviolet to the near-infrared (K), and scattered light was included in the galactic surface brightness at each wavelength. The energy absorbed throughout these ten photometric bands was assumed to re-emerge in the far-infrared as thermal dust emission. We also considered the evolutionary contraction of a constant amount of dust relative to pre-existing star distributions.
NASA Astrophysics Data System (ADS)
Khodaverdi zahraee, N.; Rastiveis, H.
2017-09-01
Earthquake is one of the most divesting natural events that threaten human life during history. After the earthquake, having information about the damaged area, the amount and type of damage can be a great help in the relief and reconstruction for disaster managers. It is very important that these measures should be taken immediately after the earthquake because any negligence could be more criminal losses. The purpose of this paper is to propose and implement an automatic approach for mapping destructed buildings after an earthquake using pre- and post-event high resolution satellite images. In the proposed method after preprocessing, segmentation of both images is performed using multi-resolution segmentation technique. Then, the segmentation results are intersected with ArcGIS to obtain equal image objects on both images. After that, appropriate textural features, which make a better difference between changed or unchanged areas, are calculated for all the image objects. Finally, subtracting the extracted textural features from pre- and post-event images, obtained values are applied as an input feature vector in an artificial neural network for classifying the area into two classes of changed and unchanged areas. The proposed method was evaluated using WorldView2 satellite images, acquired before and after the 2010 Haiti earthquake. The reported overall accuracy of 93% proved the ability of the proposed method for post-earthquake buildings change detection.
NASA Astrophysics Data System (ADS)
Lizarelli, R. F. Z.; Miguel, F. A. C.; Freitas-Pontes, K. M.; Villa, G. E. P.; Nunez, S. C.; Bagnato, V. S.
2010-11-01
Dentin hypersensitivity is a common condition associated with high dental pain. A new LED-based (light emitting diode) light source has been used as an experimental tool in some studies. Purpose: The main objective was to compare these two light sources emitting in the same spectral band (red - from 625 to 660 nm) to promote pain relief. Material and methods: A total of 6 sessions were accomplished, being three irradiation sessions and three follow-up sessions. This single-blind study compared a control group (Placebo) and two other groups with different equipments: low laser intensity treatment (LILT) and a light emitting diode system treatment (LEDT). Results: The results showed that there is no statistical difference between LILT and LEDT groups, however, both were better than control group (p <= 0.01) in terms of treatment efficiency; there is no difference between the second and the third sessions for both treatment, it means that the third session was not necessary; finally, the improvement at the end of the entire research (follow up care of 30 days) was very expressive in comparison to pre-treatment situation for all teeth (p <= 0.01). Conclusion: LILT and LEDT were equally effective to treat dentine hypersensitivity, a 3rd treatment session was not necessary/two sessions are enough.
A Yohkoh search for `black-light flares'
NASA Technical Reports Server (NTRS)
Van Driel-Gesztelyi, Lidia; Hudson, Hugh S.; Anwar, Bachtiar; Hiei, Eijiro
1994-01-01
Calculations which predict that a phenomenon analogous to stellar negative pre-flares could also exist on the Sun were published by Henoux et al. (1990), and Aboudarham et al., (1990), who showed at the beginning of a solar white-light flare (WLF) event an electron beam can cause a transient darkening before the WLF emission starts, under certain conditions. They named this event a `black light flare' (BLF). Such a BLF event should appear as diffuse dark patches lasting for about 20 seconds preceding the WLF emission, which would coincide with intense and impulsive hard X-ray bursts. The BLF location would be at (or in the vicinity of ) the forthcoming bright patches. Their predicted contrast depends on the position of the flare on the solar disk and on the wavelength band of the observation. The Yohkoh satellite provided white-light data from the aspect camera of the Soft X-ray Telescope (SXT) instrument (Tsuneta et al., 1991), at 431 nm and with a typical image interval of 10 - 12 s. We have studied nine white-light flares observed with this instrument, with X-ray class larger than M6. We have found a few interesting episodes, but no unambiguous example of the predicted BLF event. This study, although the best survey to date, was not ideal from the observational point of view. We therefore encourage further searches. Successful observations of this phenomenon on the Sun would greatly strengthen our knowledge of the lower solar atmosphere and its effects on solar luminosity variations.
Apparatus for Direct Optical Fiber Through-Lens Illumination of Microscopy or Observational Objects
NASA Technical Reports Server (NTRS)
Kadogawa, Hiroshi (Inventor)
2001-01-01
In one embodiment of the invention, a microscope or other observational apparatus, comprises a hollow tube, a lens mounted to the tube, a light source and at least one flexible optical fiber having an input end and an output end. The input end is positioned to receive light from the light source, and the output end is positioned within the tube so as to directly project light along a straight path to the lens to illuminate an object to be viewed. The path of projected light is uninterrupted and free of light deflecting elements. By passing the light through the lens, the light can be diffused or otherwise defocused to provide more uniform illumination across the surface of the object, increasing the quality of the image of the object seen by the viewer. The direct undeflected and uninterrupted projection of light, without change of direction, eliminates the need for light-deflecting elements, such as beam-splitters, mirrors, prisms, or the like, to direct the projected light towards the object.
Separation of foreground and background from light field using gradient information.
Lee, Jae Young; Park, Rae-Hong
2017-02-01
Studies of computer vision or machine vision applications using a light field camera have been increasing in recent years. However, the abilities that the light field camera has are not fully used in these applications. In this paper, we propose a method for direct separation of foreground and background that uses the gradient information and can be used in various applications such as pre-processing. From an optical phenomenon whereby the bundles of rays from the background are flipped, we derive that the disparity sign of the background in the captured three-dimensional scene has the opposite disparity sign of the foreground. Using the majority-weighted voting algorithm based on the gradient information with the Lambertian assumption and the gradient constraint, the foreground and background can be separated at each pixel. In regard to pre-processing, the proposed method can be used for various applications such as occlusion and saliency detection, disparity estimation, and so on. Experimental results with the EPFL light field dataset and Stanford Lytro light field dataset show that the proposed method achieves better performance in terms of the occlusion detection, and thus can be effectively used in pre-processing for saliency detection and disparity estimation.
The Influence of the Environment and Clothing on Human Exposure to Ultraviolet Light
Liu, Jin; Zhang, Wei
2015-01-01
Objection The aim of this study is to determine the effect of clothing and the environment on human exposure to ultraviolet light. Methods The ultraviolet (ultraviolet A and ultraviolet B) light intensity was measured, and air quality parameters were recorded in 2014 in Beijing, China. Three types of clothing (white polyester cloth, pure cotton white T-shirt, and pure cotton black T-shirt) were individually placed on a mannequin. The ultraviolet (ultraviolet A and ultraviolet B) light intensities were measured above and beneath each article of clothing, and the percentage of ultraviolet light transmission through the clothing was calculated. Results (1) The ultraviolet light transmission was significantly higher through white cloth than through black cloth; the transmission was significantly higher through polyester cloth than through cotton. (2) The weather significantly influenced ultraviolet light transmission through white polyester cloth; transmission was highest on clear days and lowest on overcast days (ultraviolet A: P=0.000; ultraviolet B: P=0.008). (3) Air quality parameters (air quality index and particulate matter 2.5 and 10) were inversely related to the ultraviolet light intensity that reached the earth’s surface. Ultraviolet B transmission through white polyester cloth was greater under conditions of low air pollution compared with high air pollution. Conclusion Clothing color and material and different types of weather affected ultraviolet light transmission; for one particular cloth, the transmission decreased with increasing air pollution. PMID:25923778
Nishiyama, Megumi; Kawaguchi, Jun
2014-11-01
To clarify the relationship between visual long-term memory (VLTM) and online visual processing, we investigated whether and how VLTM involuntarily affects the performance of a one-shot change detection task using images consisting of six meaningless geometric objects. In the study phase, participants observed pre-change (Experiment 1), post-change (Experiment 2), or both pre- and post-change (Experiment 3) images appearing in the subsequent change detection phase. In the change detection phase, one object always changed between pre- and post-change images and participants reported which object was changed. Results showed that VLTM of pre-change images enhanced the performance of change detection, while that of post-change images decreased accuracy. Prior exposure to both pre- and post-change images did not influence performance. These results indicate that pre-change information plays an important role in change detection, and that information in VLTM related to the current task does not always have a positive effect on performance. Copyright © 2014 Elsevier Inc. All rights reserved.
HTL resummation in the light cone gauge
NASA Astrophysics Data System (ADS)
Chen, Qi; Hou, De-fu
2018-04-01
The light cone gauge with light cone variables is often used in pQCD calculations in relativistic heavy-ion collision physics. The Hard Thermal Loops (HTL) resummation is an indispensable technique for hot QCD calculation. It was developed in covariant gauges with conventional Minkowski varaiables; we shall extend this method to the light cone gauge. In the real time formalism, using the Mandelstam-Leibbrant prescription of (n·K)‑1, we calculate the transverse and longitudinal components of the gluon HTL self energy, and prove that there are no infrared divergences. With this HTL self energy, we derive the HTL resummed gluon propagator in the light cone gauge. We also calculate the quark HTL self energy and the resummed quark propagator in the light cone gauge and find it is gauge independent. As application examples, we analytically calculate the damping rates of hard quarks and gluons with the HTL resummed gluon propagator in the light cone gauge and showed that they are gauge independent. The final physical results are identical to those computed in covariant gauge, as they should be. Supported by National Natural Science Foundation of China (11375070, 11735007, 11521064)
NASA Astrophysics Data System (ADS)
Liang, Yajie; Walczak, Piotr; Bulte, Jeff W. M.
2012-01-01
One critical issue for noninvasive imaging of transplanted bioluminescent cells is the large amount of light absorption in tissue when emission wavelengths below 600 nm are used. Luciferase with a red-shifted spectrum can potentially bypass this limitation. We assessed and compared a mutant of firefly luciferase (Ppy RE9, PRE9) against the yellow luciferase luc2 gene for use in cell transplantation studies. C17.2 neural stem cells expressing PRE9-Venus and luc2-Venus were sorted by flow cytometry and assessed for bioluminescence in vitro in culture and in vivo after transplantation into the brain of immunodeficient Rag2-/- mice. We found that the luminescence from PRE9 was stable, with a peak emission at 620 nm, shifted to the red compared to that of luc2. The emission peak for PRE9 was pH-independent, in contrast to luc2, and much less affected by tissue absorbance compared to that of luc2. However, the total emitted light radiance from PRE9 was substantially lower than that of luc2, both in vitro and in vivo. We conclude that PRE9 has favorable properties as compared to luc2 in terms of pH independence, red-shifted spectrum, tissue light penetration, and signal quantification, justifying further optimization of protein expression and enzymatic activity.
NASA Astrophysics Data System (ADS)
Okawa, Shinpei; Hirasawa, Takeshi; Kushibiki, Toshihiro; Ishihara, Miya
2015-03-01
Quantification of the optical properties of the tissues and blood by noninvasive photoacoustic (PA) imaging may provide useful information for screening and early diagnosis of diseases. Linearized 2D image reconstruction algorithm based on PA wave equation and the photon diffusion equation (PDE) can reconstruct the image with computational cost smaller than a method based on 3D radiative transfer equation. However, the reconstructed image is affected by the differences between the actual and assumed light propagations. A quantitative capability of a linearized 2D image reconstruction was investigated and discussed by the numerical simulations and the phantom experiment in this study. The numerical simulations with the 3D Monte Carlo (MC) simulation and the 2D finite element calculation of the PDE were carried out. The phantom experiment was also conducted. In the phantom experiment, the PA pressures were acquired by a probe which had an optical fiber for illumination and the ring shaped P(VDF-TrFE) ultrasound transducer. The measured object was made of Intralipid and Indocyanine green. In the numerical simulations, it was shown that the linearized image reconstruction method recovered the absorption coefficients with alleviating the dependency of the PA amplitude on the depth of the photon absorber. The linearized image reconstruction method worked effectively under the light propagation calculated by 3D MC simulation, although some errors occurred. The phantom experiments validated the result of the numerical simulations.
Nursing students' mathematic calculation skills.
Rainboth, Lynde; DeMasi, Chris
2006-12-01
This mixed method study used a pre-test/post-test design to evaluate the efficacy of a teaching strategy in improving beginning nursing student learning outcomes. During a 4-week student teaching period, a convenience sample of 54 sophomore level nursing students were required to complete calculation assignments, taught one calculation method, and mandated to attend medication calculation classes. These students completed pre- and post-math tests and a major medication mathematic exam. Scores from the intervention student group were compared to those achieved by the previous sophomore class. Results demonstrated a statistically significant improvement from pre- to post-test and the students who received the intervention had statistically significantly higher scores on the major medication calculation exam than did the students in the control group. The evaluation completed by the intervention group showed that the students were satisfied with the method and outcome.
Barta, András; Horváth, Gábor
2003-12-01
The apparent position, size, and shape of aerial objects viewed binocularly from water change as a result of the refraction of light at the water surface. Earlier studies of the refraction-distorted structure of the aerial binocular visual field of underwater observers were restricted to either vertically or horizontally oriented eyes. Here we calculate the position of the binocular image point of an aerial object point viewed by two arbitrarily positioned underwater eyes when the water surface is flat. Assuming that binocular image fusion is performed by appropriate vergent eye movements to bring the object's image onto the foveae, the structure of the aerial binocular visual field is computed and visualized as a function of the relative positions of the eyes. We also analyze two erroneous representations of the underwater imaging of aerial objects that have occurred in the literature. It is demonstrated that the structure of the aerial binocular visual field of underwater observers distorted by refraction is more complex than has been thought previously.
Catalytic Ignition and Upstream Reaction Propagation in Monolith Reactors
NASA Technical Reports Server (NTRS)
Struk, Peter M.; Dietrich, Daniel L.; Miller, Fletcher J.; T'ien, James S.
2007-01-01
Using numerical simulations, this work demonstrates a concept called back-end ignition for lighting-off and pre-heating a catalytic monolith in a power generation system. In this concept, a downstream heat source (e.g. a flame) or resistive heating in the downstream portion of the monolith initiates a localized catalytic reaction which subsequently propagates upstream and heats the entire monolith. The simulations used a transient numerical model of a single catalytic channel which characterizes the behavior of the entire monolith. The model treats both the gas and solid phases and includes detailed homogeneous and heterogeneous reactions. An important parameter in the model for back-end ignition is upstream heat conduction along the solid. The simulations used both dry and wet CO chemistry as a model fuel for the proof-of-concept calculations; the presence of water vapor can trigger homogenous reactions, provided that gas-phase temperatures are adequately high and there is sufficient fuel remaining after surface reactions. With sufficiently high inlet equivalence ratio, back-end ignition occurs using the thermophysical properties of both a ceramic and metal monolith (coated with platinum in both cases), with the heat-up times significantly faster for the metal monolith. For lower equivalence ratios, back-end ignition occurs without upstream propagation. Once light-off and propagation occur, the inlet equivalence ratio could be reduced significantly while still maintaining an ignited monolith as demonstrated by calculations using complete monolith heating.
NASA Astrophysics Data System (ADS)
Zhevlakov, A. S.; Radzhabov, A. E.; Dorokhov, A. E.
2010-11-01
The muon contribution to the anomalous magnetic moment from light-by-light scattering diagrams with pion participation is calculated for a nonlocal chiral quark model. For various nonlocal model parameterizations, the contribution makes a μ Had,LbL = 5.1(0.2) 10-10. Later on, we plan to calculate contributions from diagrams with an intermediate scalar meson and quark boxing.
Back focal plane microscopic ellipsometer with internal reflection geometry
NASA Astrophysics Data System (ADS)
Otsuki, Soichi; Murase, Norio; Kano, Hiroshi
2013-05-01
A back focal plane (BFP) ellipsometer is presented to measure a thin film on a cover glass using an oil-immersion high-numerical-aperture objective lens. The internal reflection geometry lowers the pseudo Brewster angle (ϕB) to the range over which the light distribution is observed in BFP of the objective. A calculation based on Mueller matrix was developed to compute ellipsometric parameters from the intensity distribution on BFP. The center and radius of the partial reflection region below the critical angle were determined and used to define a polar coordinate on BFP. Harmonic components were computed from the intensities along the azimuth direction and transformed to ellipsometric parameters at multiple incident angles around ϕB. The refractive index and thickness of the film and the contributions of the objective effect were estimated at the same time by fitting.
Narayanan, S; Orton, S; Leparc, G F; Garcia-Rubio, L H; Potter, R L
1999-10-01
A new blood typing technology based on ultraviolet (UV) and visible light spectroscopy (UV/visible spectroscopy) has been developed. Blood groups and types are determined by quantifying reproducible changes in the UV and visible light spectra of blood in the presence of agglutinating antibodies. Samples of red cells in the presence and absence of agglutinating antibodies were examined by UV/visible spectroscopy. Blood groups and types were determined by comparing the optical density spectra obtained between 665 and 1000 nm. These comparisons generate numbers (agglutination index) ranging from 0 to 100, with smaller numbers corresponding to lack of agglutination and larger numbers corresponding to agglutination. The optical density of agglutinated blood is dramatically different from that of unagglutinated blood. The agglutination index derived from the relative slopes of the spectra is an objective indicator of agglutination strength. An agglutination index greater than 17 consistently and accurately established blood group- and type-specific agglutination. The method accurately predicted A, B, and O blood groups, and D type in over 275 samples. Scattering theory-based calculations of relative volumes of red cells before and after agglutination show a direct correlation with the agglutination index and provide the theoretical basis of the analysis. This quantitative technique is reproducible and has the potential for automation.
A Multistage Approach for Image Registration.
Bowen, Francis; Hu, Jianghai; Du, Eliza Yingzi
2016-09-01
Successful image registration is an important step for object recognition, target detection, remote sensing, multimodal content fusion, scene blending, and disaster assessment and management. The geometric and photometric variations between images adversely affect the ability for an algorithm to estimate the transformation parameters that relate the two images. Local deformations, lighting conditions, object obstructions, and perspective differences all contribute to the challenges faced by traditional registration techniques. In this paper, a novel multistage registration approach is proposed that is resilient to view point differences, image content variations, and lighting conditions. Robust registration is realized through the utilization of a novel region descriptor which couples with the spatial and texture characteristics of invariant feature points. The proposed region descriptor is exploited in a multistage approach. A multistage process allows the utilization of the graph-based descriptor in many scenarios thus allowing the algorithm to be applied to a broader set of images. Each successive stage of the registration technique is evaluated through an effective similarity metric which determines subsequent action. The registration of aerial and street view images from pre- and post-disaster provide strong evidence that the proposed method estimates more accurate global transformation parameters than traditional feature-based methods. Experimental results show the robustness and accuracy of the proposed multistage image registration methodology.
ERIC Educational Resources Information Center
Kapucu, Serkan
2017-01-01
This study investigates how the acceleration and speed of a light-emitting object on an inclined plane may be determined using a smartphone's light sensor. A light-emitting object was released from the top of an inclined plane and its illuminance values were detected by a smartphone's light sensor during its subsequent motion down the plane. Using…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-31
... DEPARTMENT OF STATE [Public Notice 8136] Culturally Significant Objects Imported for Exhibition Determinations: ``Pre-Raphaelites: Victorian Art and Design, 1848- 1900'' SUMMARY: Notice is hereby given of the... exhibition ``Pre-Raphaelites: Victorian Art and Design, 1848-1900,'' imported from abroad for temporary...
Inverted light-sheet microscope for imaging mouse pre-implantation development.
Strnad, Petr; Gunther, Stefan; Reichmann, Judith; Krzic, Uros; Balazs, Balint; de Medeiros, Gustavo; Norlin, Nils; Hiiragi, Takashi; Hufnagel, Lars; Ellenberg, Jan
2016-02-01
Despite its importance for understanding human infertility and congenital diseases, early mammalian development has remained inaccessible to in toto imaging. We developed an inverted light-sheet microscope that enabled us to image mouse embryos from zygote to blastocyst, computationally track all cells and reconstruct a complete lineage tree of mouse pre-implantation development. We used this unique data set to show that the first cell fate specification occurs at the 16-cell stage.
Investigating daily fatigue scores during two-week offshore day shifts.
Riethmeister, Vanessa; Bültmann, Ute; Gordijn, Marijke; Brouwer, Sandra; de Boer, Michiel
2018-09-01
This study examined daily scores of fatigue and circadian rhythm markers over two-week offshore day shift periods. A prospective cohort study among N = 60 offshore day-shift workers working two-week offshore shifts was conducted. Offshore day shifts lasted from 07:00 - 19:00 h. Fatigue was measured objectively with pre- and post-shift scores of the 3-minute psychomotor vigilance tasks (PVT-B) parameters (reaction times, number of lapses, errors and false starts) and subjectively with pre- and post-shift Karolinska Sleepiness Scale (KSS) ratings. Evening saliva samples were collected on offshore days 2,7 and 13 to measure circadian rhythm markers such as dim-light melatonin onset times and cortisol. Generalized and linear mixed model analyses were used to examine daily fatigue scores over time. Complete data from N = 42 offshore day shift workers was analyzed. Daily parameters of objective fatigue, PVT-B scores (reaction times, average number of lapses, errors and false starts), remained stable over the course of the two-week offshore day shifts. Daily subjective post-shift fatigue scores significantly increased over the course of the two-week offshore shifts. Each day offshore was associated with an increased post-shift subjective fatigue score of 0.06 points (95%CI: .03 - .09 p < .001). No significant statistical differences in subjective pre-shift fatigue scores were found. Neither a circadian rhythm phase shift of melatonin nor an effect on the pattern and levels of evening cortisol was found. Daily parameters of objective fatigue scores remained stable over the course of the two-week offshore day shifts. Daily subjective post-shift fatigue scores significantly increased over the course of the two-week offshore shifts. No significant changes in circadian rhythm markers were found. Increased post-shift fatigue scores, especially during the last days of an offshore shift, should be considered and managed in (offshore) fatigue risk management programs and fatigue risk prediction models. Copyright © 2018 Elsevier Ltd. All rights reserved.
Colour Light And Wellbeing: A Case Study Of M Mall 020 George Town, Penang Island
NASA Astrophysics Data System (ADS)
Aqbar Zakaria, Safial; Yii Rou, Ng; Zhi En, Hoi; Iyian, Tai
2017-12-01
Contrary to popular belief, the brightest light or the most colourful light makes good lighting design. However, what makes a good lighting design in interior space is an impeccable composite of art and science. With the application of good lighting design, it can produce an impressive result from enhancing the aesthetic of architectural elements to conveying the right type of ambiance of the interiors. This research intends to address the crucial issues regarding the ways in which lighting designers can communicate the benefits of good lighting and to create a better awareness to users. The objectives of this paper are to outline and explore the features of good and poor lighting design in M Mall O2O based on the lighting design language and profession. The results of this research are mainly qualitative in nature, supported by the professional lighting designers on the definitions of good lighting, personal observation and visual data which were taken in George Town, Penang Island. The case studies on good and poor lighting portrayed in this mall were used as examples to scrutinize the issues raised herein. To achieve the optimum lighting design, a joint approach of focusing on the artistic flair brought forth by lighting and more scientific effort on the calculation levels of lights is crucial. Different functionality requires a different amount of attention on either approach. In conclusion, a good lighting design must be able to enhance the atmosphere and also enrich the quality of the interior architecture. Apart from that, a good lighting design should have good distribution of brightness levels, contrast and different colour temperatures to enhance characters of the interior spaces without neglecting the health and wellbeing aspects.
Nonparametric estimation of benchmark doses in environmental risk assessment
Piegorsch, Walter W.; Xiong, Hui; Bhattacharya, Rabi N.; Lin, Lizhen
2013-01-01
Summary An important statistical objective in environmental risk analysis is estimation of minimum exposure levels, called benchmark doses (BMDs), that induce a pre-specified benchmark response in a dose-response experiment. In such settings, representations of the risk are traditionally based on a parametric dose-response model. It is a well-known concern, however, that if the chosen parametric form is misspecified, inaccurate and possibly unsafe low-dose inferences can result. We apply a nonparametric approach for calculating benchmark doses, based on an isotonic regression method for dose-response estimation with quantal-response data (Bhattacharya and Kong, 2007). We determine the large-sample properties of the estimator, develop bootstrap-based confidence limits on the BMDs, and explore the confidence limits’ small-sample properties via a short simulation study. An example from cancer risk assessment illustrates the calculations. PMID:23914133
Domestic smoke exposure is associated with alveolar macrophage particulate load.
Fullerton, Duncan G; Jere, Khuzwayo; Jambo, Kondwani; Kulkarni, Neeta S; Zijlstra, Eduard E; Grigg, Jonathan; French, Neil; Molyneux, Malcolm E; Gordon, Stephen B
2009-03-01
Indoor air pollution is associated with impaired respiratory health. The pre-dominant indoor air pollutant to which two billion of the world's population is exposed is biomass fuel smoke. We tested the hypothesis that reported smoke exposure in men and women is associated with increased alveolar macrophage uptake of biomass smoke particulates. Healthy volunteers attending for research bronchoscopy in Malawi completed a questionnaire assessment of smoke exposure. Particulate matter visible in alveolar macrophages (AM) was quantified using digital image analysis. The geometric mean of the percentage area of the cytoplasm occupied by particulates in 50 cover-slip adherent AM was calculated and termed particulate load. In 57 subjects (40 men and 17 women) there was a significant difference between the particulate load in groups divided according to pre-dominant lighting form used at home (ANOVA P = 0.0009) and type of cooking fuel (P = 0.0078). Particulate load observed in macrophages is associated with the reported type of biomass fuel exposure. Macrophage function in relation to respiratory health should now be investigated in biomass smoke exposed subjects.
Phase Function Determination in Support of Orbital Debris Size Estimation
NASA Technical Reports Server (NTRS)
Hejduk, M. D.; Cowardin, H. M.; Stansbery, Eugene G.
2012-01-01
To recover the size of a space debris object from photometric measurements, it is necessary to determine its albedo and basic shape: if the albedo is known, the reflective area can be calculated; and if the shape is known, the shape and area taken together can be used to estimate a characteristic dimension. Albedo is typically determined by inferring the object s material type from filter photometry or spectroscopy and is not the subject of the present study. Object shape, on the other hand, can be revealed from a time-history of the object s brightness response. The most data-rich presentation is a continuous light-curve that records the object s brightness for an entire sensor pass, which could last for tens of minutes to several hours: from this one can see both short-term periodic behavior as well as brightness variations with phase angle. Light-curve interpretation, however, is more art than science and does not lend itself easily to automation; and the collection method, which requires single-object telescope dedication for long periods of time, is not well suited to debris survey conditions. So one is led to investigate how easily an object s brightness phase function, which can be constructed from the more survey-friendly point photometry, can be used to recover object shape. Such a recovery is usually attempted by comparing a phase-function curve constructed from an object s empirical brightness measurements to analytically-derived curves for basic shapes or shape combinations. There are two ways to accomplish this: a simple averaged brightness-versus phase curve assembled from the empirical data, or a more elaborate approach in which one is essentially calculating a brightness PDF for each phase angle bin (a technique explored in unpublished AFRL/RV research and in Ojakangas 2011); in each case the empirical curve is compared to analytical results for shapes of interest. The latter technique promises more discrimination power but requires more data; the former can be assembled in its essentials from fewer measurements but will be less definitive in its assignments. The goal of the present study is to evaluate both techniques under debris survey conditions to determine their relative performance and, additionally, to learn precisely how a survey should be conducted in order to maximize their performance. Because the distendedness of objects has more of an effect than their precise shape in calculating a characteristic dimension, one is interested in the techniques discrimination ability to distinguish between an elongated rectangular prism and a short rectangular prism or cube, or an elongated cylinder from a squat cylinder or sphere. Sensitivity studies using simulated data will be conducted to determine discrimination power for both techniques as a function of amount of data collected and range (and specific region) of phase angles sampled. Empirical GEODSS photometry data for distended objects (dead payloads with solar panels, rocket bodies) and compact objects (cubesats, calibration spheres, squat payloads) will also be used to test this discrimination ability. The result will be a recommended technique and data collection paradigm for debris surveys in order to maximize this type of discrimination.
Radiation doses and neutron irridation effects on human cells based on calculations
NASA Astrophysics Data System (ADS)
Radojevic, B. B.; Cukavac, M.; Jovanovic, D.
In general, main aim of our paper is to follow influence of neutron's radiation on materials, but one of possible applications of fast neutrons in therapeutical reasons i.e. their influence on carcinom cells of difficuilt geometries in human bodies too. Interactions between neutrons and human cells of tissue are analysed here. We know that the light nuclei of hydrogen, nitrogen, carbon, and oxygen are main constituents of human cells, and that different nuclear models are usually used to present interactions of nuclear particles with mentioned elements. Some of most widely used pre-equilibrium nuclear models are: intranuclear cascade model (ICN), Harp-Miller-Berne (HMB), geometry-dependent hybrid (GDH) and exciton models (EM). In this paper is studied and calculated the primary energetic spectra of the secundary particles (neutrons, protons, and gamas) emitted from this interactions, and followed by corresponding integral cross sections, based on exciton model (EM). The total emission cross-section is the sum of emissions in all stages of energies. Obtained spectra for interactions type of (n, n'), (n, p), and (n, ?), for various incident neutron energies in the interval from 3 MeV up to 30 MeV are analysed too. Some results of calculations are presented here.
The effects of laser absorption on direct-drive capsule experiments at OMEGA
NASA Astrophysics Data System (ADS)
Dodd, E. S.; Benage, J. F.; Kyrala, G. A.; Wilson, D. C.; Wysocki, F. J.; Seka, W.; Glebov, V. Yu.; Stoeckl, C.; Frenje, J. A.
2012-04-01
The yield of an inertial confinement fusion capsule can be greatly affected by the inclusion of high-Z material in the fuel, either intentionally as a diagnostic or from mixing due to hydrodynamic instabilities. To validate calculations of these conditions, glass shell targets filled with a D2 and 3He fuel mixture were fielded in experiments with controlled amounts of pre-mixed Ar, Kr, or Xe. The experiments were fielded at the OMEGA laser [T. R. Boehly et al., Opt. Commun. 133, 495 (1997)] using 1.0 ns square laser pulses having a total energy 23 kJ and direct drive illumination of shells with an outer diameter of ˜925 μm and a thickness of ˜5 μm. Data were collected and compared to one-dimensional integrated models for yield and burn-temperature measurements. This paper presents a critical examination of the calculational assumptions used in our experimental modeling. A modified treatment of laser-capsule interaction improves the match to the measured scattered laser light and also improves agreement for yields, burn-temperatures, and the fuel compression as measured by the ratio of two yields. Remaining discrepancies between measurement and calculation will also be discussed.
Local vs Nonlocal States in FeTiO3 Probed with 1s2pRIXS: Implications for Photochemistry
2017-01-01
Metal–metal charge transfer (MMCT) is expected to be the main mechanism that enables the harvesting of solar light by iron–titanium oxides for photocatalysis. We have studied FeTiO3 as a model compound for MMCT with 1s2pRIXS at the Fe K-edge. The high-energy resolution XANES enables distinguishing five pre-edge features. The three first well distinct RIXS features are assigned to electric quadrupole transitions to the localized Fe* 3d states, shifted to lower energy by the 1s core–hole. Crystal field multiplet calculations confirm the speciation of divalent iron. The contribution of electric dipole absorption due to local p-d mixing allowed by the trigonal distortion of the cation site is supported by DFT and CFM calculations. The two other nonlocal features are assigned to electric dipole transitions to excited Fe* 4p states mixed with the neighboring Ti 3d states. The comparison with DFT calculations demonstrates that MMCT in ilmenite is favored by the hybridization between the Fe 4p and delocalized Ti 3d orbitals via the O 2p orbitals. PMID:28872322
Local vs Nonlocal States in FeTiO3 Probed with 1s2pRIXS: Implications for Photochemistry.
Hunault, Myrtille O J Y; Khan, Wilayat; Minár, Jan; Kroll, Thomas; Sokaras, Dimosthenis; Zimmermann, Patric; Delgado-Jaime, Mario U; de Groot, Frank M F
2017-09-18
Metal-metal charge transfer (MMCT) is expected to be the main mechanism that enables the harvesting of solar light by iron-titanium oxides for photocatalysis. We have studied FeTiO 3 as a model compound for MMCT with 1s2pRIXS at the Fe K-edge. The high-energy resolution XANES enables distinguishing five pre-edge features. The three first well distinct RIXS features are assigned to electric quadrupole transitions to the localized Fe* 3d states, shifted to lower energy by the 1s core-hole. Crystal field multiplet calculations confirm the speciation of divalent iron. The contribution of electric dipole absorption due to local p-d mixing allowed by the trigonal distortion of the cation site is supported by DFT and CFM calculations. The two other nonlocal features are assigned to electric dipole transitions to excited Fe* 4p states mixed with the neighboring Ti 3d states. The comparison with DFT calculations demonstrates that MMCT in ilmenite is favored by the hybridization between the Fe 4p and delocalized Ti 3d orbitals via the O 2p orbitals.
Goldstein, Cathy A; Karnib, Hala; Williams, Katherine; Virk, Zunaira; Shamim-Uzzaman, Afifa
2017-11-22
Home sleep apnea tests (HSATs) are an alternative to attended polysomnograms (PSGs) when the pre-test probability for moderate to severe OSA is high. However, insurers often mandate use anytime OSA is suspected regardless of the pre-test probability. Our objective was to determine the ability of HSATs to rule in OSA when the pre-test probability of an apnea hypopnea index (AHI) in the moderate to severe range is low. Patients who underwent HSATs were characterized as low or high pre-test probability based on the presence of two symptoms of the STOP instrument plus either BMI > 35 or male gender. The odds of HSAT diagnostic for OSA dependent on pre-test probability was calculated. Stepwise selection determined predictors of non-diagnostic HSAT. As PSG is performed after HSATs that do not confirm OSA, false negative results were assessed. Among 196 individuals, pre-test probability was low in 74 (38%) and high in 122 (62%). A lower percentage of individuals with a low versus high pre-test probability for moderate to severe OSA had HSAT results that confirmed OSA (61 versus 84%, p = 0.0002) resulting in an odds ratio (OR) of 0.29 for confirmatory HSAT in the low pre-test probability group (95% CI [0.146, 0.563]). Multivariate logistic regression demonstrated that age ≤ 50 (OR 3.10 [1.24-7.73]), female gender (OR 3.58[1.50-8.66]), non-enlarged neck circumference (OR 11.50 [2.50-52.93]), and the absence of loud snoring (OR 3.47 [1.30-9.25]) best predicted non-diagnostic HSAT. OSA was diagnosed by PSG in 54% of individuals with negative HSAT which was similar in both pre-test probability groups. HSATs should be reserved for individuals with high pre-test probability for moderate to severe disease as opposed to any individual with suspected OSA.
NASA Astrophysics Data System (ADS)
Hustim, M.; Arifin, Z.; Aly, S. H.; Ramli, M. I.; Zakaria, R.; Liputo, A.
2018-04-01
This research aimed to predict the noise produced by the traffic in the road network in Makassar City using ASJ-RTN Model 2008 by calculating the horn sound. Observations were taken at 37 survey points on road side. The observations were conducted at 06.00 - 18.00 and 06.00 - 21.00 which research objects were motorcycle (MC), light vehicle (LV) and heavy vehicle (HV). The observed data were traffic volume, vehicle speed, number of horn and traffic noise using Sound Level Meter Tenmars TM-103. The research result indicates that prediction noise model by calculating the horn sound produces the average noise level value of 78.5 dB having the Pearson’s correlation and RMSE of 0.95 and 0.87. Therefore, ASJ-RTN Model 2008 prediction model by calculating the horn sound is said to be sufficiently good for predicting noise level.
Pre-Conditioning with Low-Level Laser (Light) Therapy: Light Before the Storm
Agrawal, Tanupriya; Gupta, Gaurav K.; Rai, Vikrant; Carroll, James D.; Hamblin, Michael R.
2014-01-01
Pre-conditioning by ischemia, hyperthermia, hypothermia, hyperbaric oxygen (and numerous other modalities) is a rapidly growing area of investigation that is used in pathological conditions where tissue damage may be expected. The damage caused by surgery, heart attack, or stroke can be mitigated by pre-treating the local or distant tissue with low levels of a stress-inducing stimulus, that can induce a protective response against subsequent major damage. Low-level laser (light) therapy (LLLT) has been used for nearly 50 years to enhance tissue healing and to relieve pain, inflammation and swelling. The photons are absorbed in cytochrome(c) oxidase (unit four in the mitochondrial respiratory chain), and this enzyme activation increases electron transport, respiration, oxygen consumption and ATP production. A complex signaling cascade is initiated leading to activation of transcription factors and up- and down-regulation of numerous genes. Recently it has become apparent that LLLT can also be effective if delivered to normal cells or tissue before the actual insult or trauma, in a pre-conditioning mode. Muscles are protected, nerves feel less pain, and LLLT can protect against a subsequent heart attack. These examples point the way to wider use of LLLT as a pre-conditioning modality to prevent pain and increase healing after surgical/medical procedures and possibly to increase athletic performance. PMID:25552961
Automated Meteor Detection by All-Sky Digital Camera Systems
NASA Astrophysics Data System (ADS)
Suk, Tomáš; Šimberová, Stanislava
2017-12-01
We have developed a set of methods to detect meteor light traces captured by all-sky CCD cameras. Operating at small automatic observatories (stations), these cameras create a network spread over a large territory. Image data coming from these stations are merged in one central node. Since a vast amount of data is collected by the stations in a single night, robotic storage and analysis are essential to processing. The proposed methodology is adapted to data from a network of automatic stations equipped with digital fish-eye cameras and includes data capturing, preparation, pre-processing, analysis, and finally recognition of objects in time sequences. In our experiments we utilized real observed data from two stations.
Effects of novelty and methamphetamine on conditioned and sensory reinforcement
Lloyd, David R.; Kausch, Michael A.; Gancarz, Amy M.; Beyley, Linda J.; Richards, Jerry B.
2012-01-01
Background Light onset can be both a sensory reinforcer (SR) with intrinsic reinforcing properties, and a conditioned reinforcer (CR) which predicts a biologically important reinforcer. Stimulant drugs, such as methamphetamine (METH), may increase the reinforcing effectiveness of CRs by enhancing the predictive properties of the CR. In contrast, METH-induced increases in the reinforcing effectiveness of SRs, are mediated by the immediate sensory consequences of the light. Methods The effects of novelty (on SRs) and METH (on both CRs and SRs) were tested. Experiment 1: Rats were pre-exposed to 5 s light and water pairings presented according to a variable-time (VT) 2 min schedule or unpaired water and light presented according to independent, concurrent VT 2 min schedules. Experiment 2: Rats were pre-exposed to 5 s light presented according to a VT 2 min schedule, or no stimuli. In both experiments, the pre-exposure phase was followed by a test phase in which 5 s light onset was made response-contingent on a variable-interval (VI) 2 min schedule and the effects of METH (0.5 mg/kg) were determined. Results Novel light onset was a more effective reinforcer than familiar light onset. METH increased the absolute rate of responding without increasing the relative frequency of responding for both CRs and SRs. Conclusion Novelty plays a role in determining the reinforcing effectiveness of SRs. The results are consistent with the interpretation that METH-induced increases in reinforcer effectiveness of CRs and SRs may be mediated by immediate sensory consequences, rather than prediction. PMID:22814112
Paul, Michel A; Love, Ryan J; Hawton, Andrea; Brett, Kaighley; McCreary, Donald R; Arendt, Josephine
2015-03-01
There are conflicting reports regarding seasonal sleep difficulties in polar regions. Herein we report differences in actigraphic sleep measures between two summer trials (collected at Canadian Forces Station Alert, 82.5°N, in 2012 and 2014) and evaluate exogenous melatonin for preventing/treating circadian phase delay due to nocturnal light exposure. Subjects wore actigraphs continuously to obtain sleep data. Following seven days of actigraphic recording the subjects filled out questionnaires regarding sleep difficulty and psychosocial parameters and subsequently remained in dim light conditions for 24 hours, during which saliva was collected bihourly to measure melatonin. During Trial 2, individuals who reported difficulty sleeping were prescribed melatonin, and a second saliva collection was conducted to evaluate the effect of melatonin on the circadian system. Trial 1 subjects collectively had late dim light melatonin onsets and difficulty sleeping; however, the Trial 2 subjects had normally timed melatonin rhythms, and obtained a good quantity of high-quality sleep. Nocturnal light exposure was significantly different between the trials, with Trial 1 subjects exposed to significantly more light between 2200 and 0200h. Melatonin treatment during Trial 2 led to an improvement in the subjective sleep difficulty between the pre- and post-treatment surveys; however there were no significant differences in the objective measures of sleep. The difference in sleep and melatonin rhythms between research participants in June 2012 and June 2014 is attributed to the higher levels of nocturnal light exposure in 2012. The avoidance of nocturnal light is likely to improve sleep during the Arctic summer. Crown Copyright © 2014. Published by Elsevier B.V. All rights reserved.
Image quality of the cat eye measured during retinal ganglion cell experiments.
Bonds, A B; Enroth-Cugell, C; Pinto, L H
1972-01-01
1. The modulation transfer function (MTF) of the dioptrics of fifteen cat eyes was determined. The aerial image, formed by the eye of a standard object (a 0.5-1.0 degrees annulus), was photographed. The transmission of the film negative was measured with a scanning microdensitometer to yield the light distribution within the aerial image. Correcting for the double passage, this experimentally determined light distribution and the known object light distribution were used to obtain the MTF, applying Fourier methods. Each MTF was used to calculate the light distribution within the retinal image of stimuli of various geometry used in experiments on retinal ganglion cells in the same eye.2. When the eye was equipped with an artificial pupil of the same size as that used in the neurophysiological experiments (4.0-4.8 mm diam.) the MTF had fallen to 0.5 at 2.43 c/deg. When the pupil was removed the MTF had fallen to 0.5 at a much lower spatial frequency (1.0 c/deg). This shows that even when one uses an artificial pupil too large to provide optimal image quality there is a vast improvement over using no pupil.3. These image quality measurements were prompted by the need to know the actual stimulus image in experiments on the functional organization of the receptive field, a need exemplified in this paper by a few specific physiological results. The full neurophysiological results appear in the next two papers.
Identification of Young Stellar Variables with KELT for K2 . I. Taurus Dippers and Rotators
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rodriguez, Joseph E.; Cargile, Phillip A.; Ansdell, Megan
One of the most well-studied young stellar associations, Taurus–Auriga, was observed by the extended Kepler mission, K2 , in the spring of 2017. K2 Campaign 13 (C13) is a unique opportunity to study many stars in this young association at high photometric precision and cadence. Using observations from the Kilodegree Extremely Little Telescope (KELT) survey, we identify “dippers,” aperiodic and periodic variables among K2 C13 target stars. This release of the KELT data (light curve data in e-tables) provides the community with long-time baseline observations to assist in the understanding of the more exotic variables in the association. Transient-like phenomenamore » on timescales of months to years are known characteristics in the light curves of young stellar objects, making contextual pre- and post- K2 observations critical to understanding their underlying processes. We are providing a comprehensive set of the KELT light curves for known Taurus–Auriga stars in K2 C13. The combined data sets from K2 and KELT should permit a broad array of investigations related to star formation, stellar variability, and protoplanetary environments.« less
Light clusters and pasta phases in warm and dense nuclear matter
NASA Astrophysics Data System (ADS)
Avancini, Sidney S.; Ferreira, Márcio; Pais, Helena; Providência, Constança; Röpke, Gerd
2017-04-01
The pasta phases are calculated for warm stellar matter in a framework of relativistic mean-field models, including the possibility of light cluster formation. Results from three different semiclassical approaches are compared with a quantum statistical calculation. Light clusters are considered as point-like particles, and their abundances are determined from the minimization of the free energy. The couplings of the light clusters to mesons are determined from experimental chemical equilibrium constants and many-body quantum statistical calculations. The effect of these light clusters on the chemical potentials is also discussed. It is shown that, by including heavy clusters, light clusters are present up to larger nucleonic densities, although with smaller mass fractions.
Pre-melting Behaviour in fcc Metals
NASA Astrophysics Data System (ADS)
Pamato, M. G.; Wood, I. G.; Dobson, D. P.; Hunt, S.; Vocadlo, L.
2016-12-01
Although the Earth's core is accepted to be made of an iron-nickel alloy with a few percent of light elements, its exact structure and composition are still unknown. Seismological and mineralogical models in the Earth's inner core do not agree, with mineralogical models derived from ab initiocalculations predicting shear-wave velocities up to 30% greater than seismically observed values. Recent computer simulations revealed that such difference may be explained by a dramatic, non-linear, softening of the elastic constants of Fe prior to melting. Up to date, computer calculations are the only result on pre-melting of direct applicability to the Earth's core and it is essential to systematically investigate such phenomena at inner core pressures and temperatures. Measuring the pressure dependence of pre-melting effects at such conditions and to the required precision is however extremely challenging. Also, pre-melting effects have been observed or suggested to occur in other materials, particularly noble metals, which exhibit large departures from linearity (modulus defects) at elevated temperatures. The aim of this study is to investigate to what extent pre-melting behaviour occurs in the physical properties of other metals at more experimentally tractable conditions. In particular, we report measurements of density and thermal expansion coefficients of both pure and alloyed gold (Au) up to their melting points. Au is an ideal test material since it crystallises in a simple monatomic face-centred structure and has a relatively low melting temperature. Precise measurements of unit cell lattice parameters were performed using a PANalytical X'Pert Pro powder diffractometer, equipped with an incident beam monochromator (giving very high resolution diffraction patterns) and with environmental stages covering the range from 40 K to 1373 K, with a readily achievable temperature resolution of 1K. We will discuss the circumstances under which pre-melting occurs, its mechanism(s), the effect of impurities and defects in the solid, and the consequences of pre-melting in the Earth's core.
Does pre-pregnancy BMI determine blood pressure during pregnancy? A prospective cohort study
Zuithoff, Peter; Browne, Joyce L; Amelia, Dwirani; Baharuddin, Mohammad; Grobbee, Diederick E; Uiterwaal, Cuno S P M
2016-01-01
Objectives To evaluate if pre-pregnancy body mass index (BMI) determines blood pressure throughout pregnancy and to explore the role of gestational weight gain in this association. In addition, the effects of pre-pregnancy BMI and gestational weight gain on the occurrence of gestational hypertension and pre-eclampsia were investigated. Design Prospective cohort study. Setting Maternal and child health primary care referral centre, Jakarta, Indonesia. Population and measurements 2252 pregnant women visiting Budi Kemuliaan Hospital and its branch for regular antenatal care visits from July 2012 to April 2015. Pre-pregnancy BMI (kg/m2) was based on self-reported pre-pregnancy weight and measured height at first visit. Gestational weight gain was calculated as weight at the day of delivery minus the pre-pregnancy weight. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured during pregnancy at every visit. Linear mixed models were used to analyse this relation with repeated blood pressure measures as the outcome and pre-pregnancy BMI as the predictor. When looking at gestational hypertension and pre-eclampsia as outcomes, (multiple) logistic regression was used in the analysis. Results Independent of pre-pregnancy BMI, SBP and DBP increased by 0.99 mm Hg/month and 0.46 mm Hg/month, respectively. Higher pre-pregnancy BMI was associated with higher pregnancy SBP (0.25 mm Hg/kg/m2; 95% CI 0.17 to 0.34; p<0.01) and DBP (0.18 mm Hg/kg/m2; 0.13 to 0.24; p<0.01) in adjusted analysis. Every 1 kg/m2 higher pre-pregnancy BMI was associated with 6% and 9% higher odds for gestational hypertension (adjusted OR (aOR) 1.06; 95% CI 1.03 to 1.09; p<0.01) and pre-eclampsia (aOR 1.09; 1.04 to 1.14; p<0.01). Accounting for gestational weight gain did not attenuate these associations. Conclusions Pre-pregnancy BMI determines the level, but not the change, of blood pressure in pregnancy and is linked to higher odds for gestational hypertension and pre-eclampsia, independent of gestational weight gain. PMID:27515754
Development of the IES method for evaluating the color rendition of light sources
David, Aurelien; Fini, Paul T.; Houser, Kevin W.; ...
2015-06-08
We have developed a two-measure system for evaluating light sources’ color rendition that builds upon conceptual progress of numerous researchers over the last two decades. The system quantifies the color fidelity and color gamut (change in object chroma) of a light source in comparison to a reference illuminant. The calculations are based on a newly developed set of reflectance data from real samples uniformly distributed in color space (thereby fairly representing all colors) and in wavelength space (thereby precluding artificial optimization of the color rendition scores by spectral engineering). The color fidelity score R f is an improved version ofmore » the CIE color rendering index. The color gamut score R g is an improved version of the Gamut Area Index. In combination, they provide two complementary assessments to guide the optimization of future light sources. This method summarizes the findings of the Color Metric Task Group of the Illuminating Engineering Society of North America (IES). It is adopted in the upcoming IES TM-30-2015, and is proposed for consideration with the International Commission on Illumination (CIE).« less
Khiewkhern, Santisith; Promthet, Supannee; Sukprasert, Aemkhea; Eunhpinitpong, Wichai; Bradshaw, Peter
2013-01-01
Patients with colorectal cancer are usually treated with chemotherapy, which reduces the number of blood cells, especially white blood cells, and consequently increases the risk of infections. Some research studies have reported that aromatherapy massage affects the immune system and improves immune function by, for example, increasing the numbers of natural killer cells and peripheral blood lymphocytes. However, there has been no report of any study which provided good evidence as to whether aromatherapy with Thai massage could improve the immune system in patients with colorectal cancer. The objectives of this study were to determine whether the use of aromatherapy with light Thai massage in patients with colorectal cancer, who have received chemotherapy, can result in improvement of the cellular immunity and reduce the severity of the common symptoms of side effects. Sixty-six patients with colorectal cancer in Phichit Hospital, Thailand, were enrolled in a single-blind, randomised-controlled trial. The intervention consisted of three massage sessions with ginger and coconut oil over a 1-week period. The control group received standard supportive care only. Assessments were conducted at pre-assessment and at the end of one week of massage or standard care. Changes from pre-assessment to the end of treatment were measured in terms of white blood cells, neutrophils, lymphocytes, CD4 and CD8 cells and the CD4/CD8 ratio and also the severity of self-rated symptom scores. The main finding was that after adjusting for pre-assessment values the mean lymphocyte count at the post-assessment was significantly higher (P=0.04) in the treatment group than in the controls. The size of this difference suggested that aromatherapy with Thai massage could boost lymphocyte numbers by 11%. The secondary outcomes were that at the post assessment the symptom severity scores for fatigue, presenting symptom, pain and stress were significantly lower in the massage group than in the standard care controls. Aromatherapy with light Thai massage can be beneficial for the immune systems of cancer patients who are undergoing chemotherapy by increasing the number of lymphocytes and can help to reduce the severity of common symptoms.
Gender approaches to evolutionary multi-objective optimization using pre-selection of criteria
NASA Astrophysics Data System (ADS)
Kowalczuk, Zdzisław; Białaszewski, Tomasz
2018-01-01
A novel idea to perform evolutionary computations (ECs) for solving highly dimensional multi-objective optimization (MOO) problems is proposed. Following the general idea of evolution, it is proposed that information about gender is used to distinguish between various groups of objectives and identify the (aggregate) nature of optimality of individuals (solutions). This identification is drawn out of the fitness of individuals and applied during parental crossover in the processes of evolutionary multi-objective optimization (EMOO). The article introduces the principles of the genetic-gender approach (GGA) and virtual gender approach (VGA), which are not just evolutionary techniques, but constitute a completely new rule (philosophy) for use in solving MOO tasks. The proposed approaches are validated against principal representatives of the EMOO algorithms of the state of the art in solving benchmark problems in the light of recognized EC performance criteria. The research shows the superiority of the gender approach in terms of effectiveness, reliability, transparency, intelligibility and MOO problem simplification, resulting in the great usefulness and practicability of GGA and VGA. Moreover, an important feature of GGA and VGA is that they alleviate the 'curse' of dimensionality typical of many engineering designs.
Detecting Lateral Motion using Light's Orbital Angular Momentum.
Cvijetic, Neda; Milione, Giovanni; Ip, Ezra; Wang, Ting
2015-10-23
Interrogating an object with a light beam and analyzing the scattered light can reveal kinematic information about the object, which is vital for applications ranging from autonomous vehicles to gesture recognition and virtual reality. We show that by analyzing the change in the orbital angular momentum (OAM) of a tilted light beam eclipsed by a moving object, lateral motion of the object can be detected in an arbitrary direction using a single light beam and without object image reconstruction. We observe OAM spectral asymmetry that corresponds to the lateral motion direction along an arbitrary axis perpendicular to the plane containing the light beam and OAM measurement axes. These findings extend OAM-based remote sensing to detection of non-rotational qualities of objects and may also have extensions to other electromagnetic wave regimes, including radio and sound.
NASA Astrophysics Data System (ADS)
Savidge, Rodney
Wild type (Col 0) Arabidopsis thaliana were grown in a growth chamber within the single mid-deck sized Advanced Biological Research System (ABRS) spaceflight hardware developed by NASA Kennedy Space Center. Before beginning this experiment, the plants, each rooted in individual transferable tubes containing nutrients, were cultivated hydroponically on halfstrength Hoagland's solution beneath either LED lighting similar to that provided by the ABRS growth chamber or white fluorescent lighting. The leaves of the basal whorl of plants pre-grown in ABRS lighting were small and purplish at the start of the experiment, whereas those under fluorescent lighting were larger and green. The plants were transferred to the ABRS soon after their inflorescence axes had started to elongate, and thereafter they were maintained under preset conditions (22 o C, approximately 1500 ppm CO2 , predominantly 125 µmol m-2 s-1 PAR) with pulses of water provided at 1-3 d intervals (as needed) to the module into which the root tubes were inserted. That module was pre-treated with half-strength Hoagland's nutrient solution on day 0, but no additional nutrients were provided the plants thereafter. Strong primary growth of all inflorescence stems occurred soon after initiating the ABRS experiment, and the plants began forming an overarching canopy of flowering stems beneath the LED lighting module within two weeks. After 38 days the root module was littered with seeds, siliques and abscised leaves, but all plants remained alive. Plants pre-grown in ABRS lighting were more advanced toward senescence, and leaves and stems of plants pre-grown in fluorescent lighting although greener were also acquiring a purplish hue. Microscopy revealed that the flowering stems achieved no secondary growth; however, progressive inward conversion of pith parenchyma into sclerenchyma cells did occur resulting in the inflorescence stems becoming abnormally woody.
The Robustness of Pre-School Children's Tendency to Count Discrete Physical Objects
ERIC Educational Resources Information Center
Fletcher, Ben; Pine, Karen J.
2009-01-01
When pre-school children count an array of objects containing one that is broken in half, most count the halves as two separate objects. Two studies explore this predisposition to count discrete physical objects (DPOs) and investigate its robustness in the face of various manipulations. In Experiment 1, 32 children aged three-four years counted…
NASA Technical Reports Server (NTRS)
Dunne, Matthew J.
2011-01-01
The development of computer software as a tool to generate visual displays has led to an overall expansion of automated computer generated images in the aerospace industry. These visual overlays are generated by combining raw data with pre-existing data on the object or objects being analyzed on the screen. The National Aeronautics and Space Administration (NASA) uses this computer software to generate on-screen overlays when a Visiting Vehicle (VV) is berthing with the International Space Station (ISS). In order for Mission Control Center personnel to be a contributing factor in the VV berthing process, computer software similar to that on the ISS must be readily available on the ground to be used for analysis. In addition, this software must perform engineering calculations and save data for further analysis.
Data processing and optimization system to study prospective interstate power interconnections
NASA Astrophysics Data System (ADS)
Podkovalnikov, Sergei; Trofimov, Ivan; Trofimov, Leonid
2018-01-01
The paper presents Data processing and optimization system for studying and making rational decisions on the formation of interstate electric power interconnections, with aim to increasing effectiveness of their functioning and expansion. The technologies for building and integrating a Data processing and optimization system including an object-oriented database and a predictive mathematical model for optimizing the expansion of electric power systems ORIRES, are described. The technology of collection and pre-processing of non-structured data collected from various sources and its loading to the object-oriented database, as well as processing and presentation of information in the GIS system are described. One of the approaches of graphical visualization of the results of optimization model is considered on the example of calculating the option for expansion of the South Korean electric power grid.
Depth Perception in Space (Artist's Concept)
NASA Technical Reports Server (NTRS)
2007-01-01
This artist's concept shows how astronomers use the unique orbit of NASA's Spitzer Space Telescope and a depth-perceiving trick called parallax to determine the distance of dark planets, black holes and failed stars that lurk invisibly among us. These objects do not produce light, and are too faint to detect from Earth. However, astronomers can deduce their presence from the way they affect the light from background objects. When such a dark body passes in front of a bright star, its gravity warps the path of the star's light and causes it to brighten -- this process is called gravitational microlensing. By comparing the 'peak brightness' of the microlensing event from two perspectives -- Earth and Spitzer -- scientists can determine how far away the dark object is. Peak brightness is the moment when the observer, the dark object and background star are most closely aligned. Humans naturally use parallax to determine distance -- this is commonly referred to as depth perception. In the case of humans, each eye sees the position of an object differently. The brain takes each eye's perspective, and instantaneously calculates how far away the object is. In space, astronomers can use the same trick to determine the distance of an invisible dark object. In this illustration, the dark object is the moving black ball between Earth, Spitzer and our neighboring galaxy the Small Magellanic Cloud (SMC; bottom right). To determine the object's distance, astronomers observe the microlensing event at its 'peak brightness' from Earth when the dark object crosses our line-of-sight (dashed line) to a given star in the SMC. This represents one perspective, like looking at an object with only your left eye. To get the other 'right eye' perspective, astronomers also observe the peak brightness with Spitzer when the object later moves through its line-of-sight. Because astronomers know the exact distance between Earth and Spitzer, they can determine the dark body's speed by timing how long it took for Spitzer to see peak brightness after astronomers observed the event on Earth. Using trigonometric equations and graphs to do the 'brain's' job, scientists can infer the dark body's distance. The scales in this diagram are greatly exaggerated for clarity. The distance between Spitzer and the Earth is miniscule in comparison to the distance to the dark object and SMC. Since microlensing events require extremely precise alignments, even such a tiny separation is enough to measure these objects out to tremendous distances.Surface tension mediated conversion of light to work
Okawa, David; Pastine, Stefan J; Zettl, Alexander K; Frechet, Jean M. J
2014-12-02
Disclosed are a method and apparatus for converting light energy to mechanical energy by modification of surface tension on a supporting fluid. The apparatus comprises an object which may be formed as a composite object comprising a support matrix and a highly light absorptive material. The support matrix may comprise a silicon polymer. The highly light absorptive material may comprise vertically aligned carbon nanotubes (VANTs) embedded in the support matrix. The composite object is supported on a fluid. By exposing the highly light absorptive material to light, heat is generated, which changes the surface tension of the composite object, causing it to move physically within the fluid.
CMOS image sensor with contour enhancement
NASA Astrophysics Data System (ADS)
Meng, Liya; Lai, Xiaofeng; Chen, Kun; Yuan, Xianghui
2010-10-01
Imitating the signal acquisition and processing of vertebrate retina, a CMOS image sensor with bionic pre-processing circuit is designed. Integration of signal-process circuit on-chip can reduce the requirement of bandwidth and precision of the subsequent interface circuit, and simplify the design of the computer-vision system. This signal pre-processing circuit consists of adaptive photoreceptor, spatial filtering resistive network and Op-Amp calculation circuit. The adaptive photoreceptor unit with a dynamic range of approximately 100 dB has a good self-adaptability for the transient changes in light intensity instead of intensity level itself. Spatial low-pass filtering resistive network used to mimic the function of horizontal cell, is composed of the horizontal resistor (HRES) circuit and OTA (Operational Transconductance Amplifier) circuit. HRES circuit, imitating dendrite of the neuron cell, comprises of two series MOS transistors operated in weak inversion region. Appending two diode-connected n-channel transistors to a simple transconductance amplifier forms the OTA Op-Amp circuit, which provides stable bias voltage for the gate of MOS transistors in HRES circuit, while serves as an OTA voltage follower to provide input voltage for the network nodes. The Op-Amp calculation circuit with a simple two-stage Op-Amp achieves the image contour enhancing. By adjusting the bias voltage of the resistive network, the smoothing effect can be tuned to change the effect of image's contour enhancement. Simulations of cell circuit and 16×16 2D circuit array are implemented using CSMC 0.5μm DPTM CMOS process.
Code of Federal Regulations, 2011 CFR
2011-07-01
... impairment. A deciview is a haze index derived from calculated light extinction, such that uniform changes in... (for the purposes of calculating deciview, the atmospheric light extinction coefficient must be... light extinction coefficient, expressed in inverse megameters (Mm−1). Existing stationary facility means...
Code of Federal Regulations, 2010 CFR
2010-07-01
... impairment. A deciview is a haze index derived from calculated light extinction, such that uniform changes in... (for the purposes of calculating deciview, the atmospheric light extinction coefficient must be... light extinction coefficient, expressed in inverse megameters (Mm−1). Existing stationary facility means...
Code of Federal Regulations, 2012 CFR
2012-07-01
... impairment. A deciview is a haze index derived from calculated light extinction, such that uniform changes in... (for the purposes of calculating deciview, the atmospheric light extinction coefficient must be... light extinction coefficient, expressed in inverse megameters (Mm−1). Existing stationary facility means...
Code of Federal Regulations, 2013 CFR
2013-07-01
... impairment. A deciview is a haze index derived from calculated light extinction, such that uniform changes in... (for the purposes of calculating deciview, the atmospheric light extinction coefficient must be... light extinction coefficient, expressed in inverse megameters (Mm−1). Existing stationary facility means...
ERIC Educational Resources Information Center
Bektas, Oktay
2015-01-01
This study investigated pre-service science teachers' pedagogical content knowledge in the physics, chemistry, and biology topics. These topics were the light and sound, the physical and chemical changes, and reproduction, growth, and evolution. Qualitative research design was utilized. Data were collected from 33 pre-service science teachers…
Microcomputer Calculation of Theoretical Pre-Exponential Factors for Bimolecular Reactions.
ERIC Educational Resources Information Center
Venugopalan, Mundiyath
1991-01-01
Described is the application of microcomputers to predict reaction rates based on theoretical atomic and molecular properties taught in undergraduate physical chemistry. Listed is the BASIC program which computes the partition functions for any specific bimolecular reactants. These functions are then used to calculate the pre-exponential factor of…
Light Curve Simulation Using Spacecraft CAD Models and Empirical Material Spectral BRDFS
NASA Astrophysics Data System (ADS)
Willison, A.; Bedard, D.
This paper presents a Matlab-based light curve simulation software package that uses computer-aided design (CAD) models of spacecraft and the spectral bidirectional reflectance distribution function (sBRDF) of their homogenous surface materials. It represents the overall optical reflectance of objects as a sBRDF, a spectrometric quantity, obtainable during an optical ground truth experiment. The broadband bidirectional reflectance distribution function (BRDF), the basis of a broadband light curve, is produced by integrating the sBRDF over the optical wavelength range. Colour-filtered BRDFs, the basis of colour-filtered light curves, are produced by first multiplying the sBRDF by colour filters, and integrating the products. The software package's validity is established through comparison of simulated reflectance spectra and broadband light curves with those measured of the CanX-1 Engineering Model (EM) nanosatellite, collected during an optical ground truth experiment. It is currently being extended to simulate light curves of spacecraft in Earth orbit, using spacecraft Two-Line-Element (TLE) sets, yaw/pitch/roll angles, and observer coordinates. Measured light curves of the NEOSSat spacecraft will be used to validate simulated quantities. The sBRDF was chosen to represent material reflectance as it is spectrometric and a function of illumination and observation geometry. Homogeneous material sBRDFs were obtained using a goniospectrometer for a range of illumination and observation geometries, collected in a controlled environment. The materials analyzed include aluminum alloy, two types of triple-junction photovoltaic (TJPV) cell, white paint, and multi-layer insulation (MLI). Interpolation and extrapolation methods were used to determine the sBRDF for all possible illumination and observation geometries not measured in the laboratory, resulting in empirical look-up tables. These look-up tables are referenced when calculating the overall sBRDF of objects, where the contribution of each facet is proportionally integrated.
de Araujo Toloi, Diego; Uema, Deise; Matsushita, Felipe; da Silva Andrade, Paulo Antonio; Branco, Tiago Pugliese; de Carvalho Chino, Fabiana Tomie Becker; Guerra, Raquel Bezerra; Pfiffer, Túlio Eduardo Flesch; Chiba, Toshio; Guindalini, Rodrigo Santa Cruz; Sulmasy, Daniel P; Riechelmann, Rachel P
2016-01-01
Summary Objectives Spirituality is related to the care and the quality of life of cancer patients. Thus, it is very important to assess their needs. The objective of this study was the translation and cultural adjustment of the Spiritual Needs Assessment for Patients (SNAP) questionnaire to the Brazilian Portuguese language. Methodology The translation and cultural adjustment of the SNAP questionnaire involved six stages: backtranslation, revision of backtranslation, translation to the original language and adjustments, pre-test on ten patients, and test and retest with 30 patients after three weeks. Adult patients, with a solid tumour and literate with a minimum of four years schooling were included. For analysis and consistency we used the calculation of the Cronbach alpha coefficient and the Pearson linear correlation. Results The final questionnaire had some language and content adjustments compared to the original version in English. The correlation analysis of each item with the total score of the questionnaire showed coefficients above 0.99. The calculation of the Cronbach alpha coefficient was 0.9. The calculation of the Pearson linear correlation with the test and retest of the questionnaire was equal to 0.95. Conclusion The SNAP questionnaire translated into Brazilian Portuguese is adequately reliable and consistent. This instrument allows adequate access to spiritual needs and can help patient care. PMID:28101137
Asteroid (367943) 2012 DA14 Flyby Spin State Analysis
NASA Astrophysics Data System (ADS)
Benson, Conor; Scheeres, Daniel J.; Moskovitz, Nicholas
2017-10-01
On February 15, 2013 asteroid 2012 DA14 experienced an extremely close Earth encounter, passing within 27700 km altitude. This flyby gave observers the chance to directly detect flyby-induced changes to the asteroid’s spin state and physical properties. The strongest shape and spin state constraints were provided by Goldstone delay-Doppler radar and visible-wavelength photometry taken after closest approach. These data indicated a roughly 40 m x 20 m object in non-principal axis rotation. NPA states are described by two fundamental periods. Pφ is the average precession period of the long/short axis about the angular momentum vector and Pψ is the rotation period about the long/short axis.WindowCLEAN (Belton & Gandhi 1988) power spectrum analysis of the post flyby light curve showed three prominent frequencies, two of which were 1:2 multiples of each other. Mueller et al. (2002) suggest peaks with this relationship are 1/Pφ and 2/Pφ, implying that Pφ = 6.35 hr. Likely values for Pψ were then 8.72, 13.95, or 23.39 hr. These Pφ,Pψ pairs yielded six candidate spin states in total, one LAM and one SAM per pair.Second to fourth order, two-dimensional Fourier series fits to the light curve were best for periods of 6.359 and 8.724 hr. The two other candidate pairs were also in the top ten fits. Inertia constraints of a roughly 2:1 uniform density ellipsoid eliminated two of the three SAM states. Using JPL Horizons ephemerides and Lambertian ellipsoids, simulated light curves were generated. The simulated and observed power spectra were then compared for all angular momentum poles and reasonable ellipsoid elongations. Only the Pφ = 6.359 hr and Pψ = 8.724 hr LAM state produced light curves consistent with the observed frequency structure. All other states were clearly incompatible. With two well-fitting poles found, phasing the initial attitude and angular velocity yielded plausible matches to the observed light curve. Neglecting gravitational torques, neither pole agreed with the observed pre-flyby light curve, suggesting that the asteroid’s spin state changed during the encounter, consistent with numerical simulation predictions. The consistency between the pre-flyby observations and simulated states will be discussed.
An integrated fiberoptic-microfluidic device for agglutination detection and blood typing.
Ramasubramanian, Melur K; Alexander, Stewart P
2009-02-01
In this paper, an integrated fiberoptic-microfluidic device for the detection of agglutination for blood type cross-matching has been described. The device consists of a straight microfluidic channel through with a reacted RBC suspension is pumped with the help of a syringe pump. The flow intersects an optical path created by an emitter-received fiber optic pair integrated into the microfluidic device. A 650 nm laser diode is used as the light source and a silicon photodiode is used to detect the light intensity. The spacing between the tips of the two optic fibers can be adjusted. When fiber spacing is large and the concentration of the suspension is high, scattering phenomenon becomes the dominant mechanism for agglutination detection while at low concentrations and small spacing, optointerruption becomes the dominant mechanism. An agglutination strength factor (ASF) is calculated from the data. Studies with a variety of blood types indicate that the sensing method correctly identifies the agglutination reaction in all cases. A disposable integrated device can be designed for future implementation of the method for near-bedside pre-transfusion check.
Concept of white light in stage lighting
NASA Astrophysics Data System (ADS)
Rinaldi, Mauricio R.
2002-06-01
In perceiving objects, generally we see them in a white light situation. But, actually, there is not an absolute white, in such a manner that the different light sources have a determined kind of white, what it is known as color temperature. Even the white light may be of different kinds (different color temperature), the individual mind tends to perceive it as the same kind of white, that is to say, there is in our mind a psychological function by which we operate an integration in the perception in order to do the object perceptually invariable. On the other hand, it is a common practice in stage lighting to use color light sources. It is a well known phenomenon that a color of light produces a change in the object color perception. However, when we go to theater, we see the objects as having their real color, even if the lighting is not white. In this paper the concept of white light in stage lighting is presented, showing its possibilities of aesthetical expression.
DOE Office of Scientific and Technical Information (OSTI.GOV)
David, Aurelien; Fini, Paul T.; Houser, Kevin W.
We have developed a two-measure system for evaluating light sources’ color rendition that builds upon conceptual progress of numerous researchers over the last two decades. The system quantifies the color fidelity and color gamut (change in object chroma) of a light source in comparison to a reference illuminant. The calculations are based on a newly developed set of reflectance data from real samples uniformly distributed in color space (thereby fairly representing all colors) and in wavelength space (thereby precluding artificial optimization of the color rendition scores by spectral engineering). The color fidelity score R f is an improved version ofmore » the CIE color rendering index. The color gamut score R g is an improved version of the Gamut Area Index. In combination, they provide two complementary assessments to guide the optimization of future light sources. This method summarizes the findings of the Color Metric Task Group of the Illuminating Engineering Society of North America (IES). It is adopted in the upcoming IES TM-30-2015, and is proposed for consideration with the International Commission on Illumination (CIE).« less
Transit timing analysis of the exoplanet TrES-5 b. Possible existence of the exoplanet TrES-5 c
NASA Astrophysics Data System (ADS)
Sokov, Eugene N.; Sokova, Iraida A.; Dyachenko, Vladimir V.; Rastegaev, Denis A.; Burdanov, Artem; Rusov, Sergey A.; Benni, Paul; Shadick, Stan; Hentunen, Veli-Pekka; Salisbury, Mark; Esseiva, Nicolas; Garlitz, Joe; Bretton, Marc; Ogmen, Yenal; Karavaev, Yuri; Ayiomamitis, Anthony; Mazurenko, Oleg; Alonso, David Molina; Velichko, Sergey F.
2018-06-01
In this work, we present transit timing variations detected for the exoplanet TrES-5b. To obtain the necessary amount of photometric data for this exoplanet, we have organized an international campaign to search for exoplanets based on the Transit Timing Variation method (TTV) and as a result of this we collected 30 new light curves, 15 light curves from the Exoplanet Transit Database (ETD) and 8 light curves from the literature for the timing analysis of the exoplanet TrES-5b. We have detected timing variations with a semi-amplitude of A ≈ 0.0016 days and a period of P ≈ 99 days. We carried out the N-body modeling based on the three-body problem. The detected perturbation of TrES-5b may be caused by a second exoplanet in the TrES-5 system. We have calculated the possible mass and resonance of the object: M ≈ 0.24MJup at a 1:2 Resonance.
Target Recognition Using Neural Networks for Model Deformation Measurements
NASA Technical Reports Server (NTRS)
Ross, Richard W.; Hibler, David L.
1999-01-01
Optical measurements provide a non-invasive method for measuring deformation of wind tunnel models. Model deformation systems use targets mounted or painted on the surface of the model to identify known positions, and photogrammetric methods are used to calculate 3-D positions of the targets on the model from digital 2-D images. Under ideal conditions, the reflective targets are placed against a dark background and provide high-contrast images, aiding in target recognition. However, glints of light reflecting from the model surface, or reduced contrast caused by light source or model smoothness constraints, can compromise accurate target determination using current algorithmic methods. This paper describes a technique using a neural network and image processing technologies which increases the reliability of target recognition systems. Unlike algorithmic methods, the neural network can be trained to identify the characteristic patterns that distinguish targets from other objects of similar size and appearance and can adapt to changes in lighting and environmental conditions.
Assessing human skin with diffuse reflectance spectroscopy and colorimetry
NASA Astrophysics Data System (ADS)
Seo, InSeok; Liu, Yang; Bargo, Paulo R.; Kollias, Nikiforos
2012-02-01
Colorimetry has been used as an objective measure of perceived skin color by human eye to document and score physiological responses of the skin from external insults. CIE color space values (L*, a* and b*) are the most commonly used parameters to correlate visually perceived color attributes such as L* for pigment, a* for erythema, and b* for sallowness of the skin. In this study, we investigated the relation of Lab color scale to the amount of major skin chromophores (oxy-, deoxyhemoglobin and melanin) calculated from diffuse reflectance spectroscopy. Thirty two healthy human subjects with ages from 20 to 70 years old, skin types I-VI, were recruited for the study. DRS and colorimetry measurements were taken from the left and right cheeks, and on the right upper inner arm. The melanin content calculated from 630-700 nm range of DRS measurements was shown to correlate with the lightness of skin (L*) for most skin types. For subjects with medium-to-light complexion, melanin measured at the blue part spectrum and hemoglobin interfered on the relation of lightness of the skin color to the melanin content. The sallowness of the skin that is quantified by the melanin contribution at the blue part spectrum of DRS was found to be related to b* scale. This study demonstrates the importance of documenting skin color by assessing individual skin chromophores with diffuse reflectance spectroscopy, in comparison to colorimetry assessment.
Experimental investigations into visual and electronic tooth color measurement.
Ratzmann, Anja; Treichel, Anja; Langforth, Gabriele; Gedrange, Tomasz; Welk, Alexander
2011-04-01
The present study aimed to examine the validity of the visual color assessment and an electronic tooth color measurement system by means of Shade Inspector™ in comparison with a gold standard. Additionally, reproducibility of electronic measurements was demonstrated by means of two reference systems. Ceramic specimens of two thicknesses (h=1.6 mm, h=2.6 mm) were used. Three experienced dental technicians using the VITAPAN Classical(®) color scale carried out all visual tests. Validity of the visual assessment and the electronic measurements was confirmed separately for both thicknesses by means of lightness and hue of the VITAPAN Classical(®) color scale. Reproducibility of electronic measurements was confirmed by means of the VITAPAN Classical(®) and 3D-Master(®). The 3D-Master(®) data were calculated according to lightness, hue and chroma. Intraclass correlation coefficient (ICC) was used in assessing validity/reproducibility for lightness and chroma, Kappa statistics were used for hue. A level ≥0.75 was pre-established for ICC and ≥0.60 for the Kappa index. RESULTS OF VISUAL COLOR ASSESSMENT: Validity for lightness was good for both thicknesses; agreement rates for hue were inconsistent. ELECTRONIC MEASUREMENT: Validity for lightness was fair to good, hue values were below 0.60. Reproducibility of lightness was good to very good for both reference systems. Hue values (VITAPAN Classical(®)) for 1.6 mm test specimens were upside, for 2.6 mm below 0.60, Kappa values for 3D-Master(®) were ≥0.60 for all measurements, reproducibility of chroma was very good. Validity was better for visual than for electronic color assessment. Reproducibility of the electronic device by means of the Shade Inspector™ was given for the VITAPAN Classical(®) and 3D-Master(®) systems.
Terrace retro-reflector array for poloidal polarimeter on ITER.
Imazawa, R; Kawano, Y; Ono, T; Kusama, Y
2011-02-01
A new concept of a terrace retro-reflector array (TERRA) as part of the poloidal polarimeter for ITER is proposed in this paper. TERRA reflects a laser light even from a high incident angle in the direction of the incident-light path, while a conventional retro-reflector array cannot. Besides, TERRA can be installed in a smaller space than a corner-cube retro-reflector. In an optical sense, TERRA is equivalent to a Littrow grating, the blaze angle of which varies, depending on the incident angle. The reflected light generates a bright and dark fringe, and the bright fringe is required to travel along the incident-light path to achieve the objects of laser-aided diagnostics. In order to investigate the propagation properties of laser light reflected by TERRA, we have developed a new diffraction formula. Conditions for the propagation of the bright fringe in the direction of the incident light have been obtained using the Littrow grating model and have been confirmed in a simulation applying the new diffraction formula. Finally, we have designed laser transmission optics using TERRA for the ITER poloidal polarimeter and have calculated the light propagation of the system. The optical design obtains a high transmission efficiency, with 88.6% of the incident power returned. These results demonstrate the feasibility of applying TERRA to the ITER poloidal polarimeter.
Computer Generated Holography with Intensity-Graded Patterns
Conti, Rossella; Assayag, Osnath; de Sars, Vincent; Guillon, Marc; Emiliani, Valentina
2016-01-01
Computer Generated Holography achieves patterned illumination at the sample plane through phase modulation of the laser beam at the objective back aperture. This is obtained by using liquid crystal-based spatial light modulators (LC-SLMs), which modulate the spatial phase of the incident laser beam. A variety of algorithms is employed to calculate the phase modulation masks addressed to the LC-SLM. These algorithms range from simple gratings-and-lenses to generate multiple diffraction-limited spots, to iterative Fourier-transform algorithms capable of generating arbitrary illumination shapes perfectly tailored on the base of the target contour. Applications for holographic light patterning include multi-trap optical tweezers, patterned voltage imaging and optical control of neuronal excitation using uncaging or optogenetics. These past implementations of computer generated holography used binary input profile to generate binary light distribution at the sample plane. Here we demonstrate that using graded input sources, enables generating intensity graded light patterns and extend the range of application of holographic light illumination. At first, we use intensity-graded holograms to compensate for LC-SLM position dependent diffraction efficiency or sample fluorescence inhomogeneity. Finally we show that intensity-graded holography can be used to equalize photo evoked currents from cells expressing different levels of chanelrhodopsin2 (ChR2), one of the most commonly used optogenetics light gated channels, taking into account the non-linear dependence of channel opening on incident light. PMID:27799896
Semantic memory retrieval circuit: role of pre-SMA, caudate, and thalamus.
Hart, John; Maguire, Mandy J; Motes, Michael; Mudar, Raksha Anand; Chiang, Hsueh-Sheng; Womack, Kyle B; Kraut, Michael A
2013-07-01
We propose that pre-supplementary motor area (pre-SMA)-thalamic interactions govern processes fundamental to semantic retrieval of an integrated object memory. At the onset of semantic retrieval, pre-SMA initiates electrical interactions between multiple cortical regions associated with semantic memory subsystems encodings as indexed by an increase in theta-band EEG power. This starts between 100-150 ms after stimulus presentation and is sustained throughout the task. We posit that this activity represents initiation of the object memory search, which continues in searching for an object memory. When the correct memory is retrieved, there is a high beta-band EEG power increase, which reflects communication between pre-SMA and thalamus, designates the end of the search process and resultant in object retrieval from multiple semantic memory subsystems. This high beta signal is also detected in cortical regions. This circuit is modulated by the caudate nuclei to facilitate correct and suppress incorrect target memories. Copyright © 2012 Elsevier Inc. All rights reserved.
The Light and Period Variations of the Eclipsing Binary BX Draconis
NASA Astrophysics Data System (ADS)
Park, Jang-Ho; Lee, Jae Woo; Kim, Seung-Lee; Lee, Chung-Uk; Jeon, Young-Beom
2013-02-01
New CCD photometric observations of BX Dra were carried out on 26 nights during the period from 2009 April to 2010 June. The long-term photometric behaviors of the system are obtained from detailed studies of the period and light variations, based on historical data and our new observations. All available light curves display total eclipses at secondary minima and inverse O'Connell effects with Max I fainter than Max II, which were satisfactorily modeled by adding a slightly time-varying hot spot on the primary star. A total of 87 times of minimum lights spanning over ˜74 yr, including our 22 timing measurements, were used for ephemeris computations. A detailed analysis of the O - C diagram disclosed that the orbital period shows an upward parabola in combination with a sinusoidal variation. The continuous increase of period at a rate of +5.65 × 10-7 d yr-1 is consistent with that calculated from the Wilson-Devinney synthesis code. It can be interpreted as a mass transfer from the secondary star to the primary at a rate of 2.74 × 10-7 M⊙ yr-1, which is one of the largest rates between components of the contact system. The most likely explanation of the sinusoidal variation having a period of 30.2 yr and a semiamplitude of 0.0062 d is a light-travel-time effect due to the existence of a circumbinary object. We suggest that BX Dra is probably a triple system, consisting of a primary star with a spectral type of F0, its secondary component of spectral type F1-2, and an unseen circumbinary object with a minimum mass of M3 = 0.23 M⊙.
Light drives vertical gradients of leaf morphology in a sugar maple (Acer saccharum) forest.
Coble, Adam P; Cavaleri, Molly A
2014-02-01
Leaf mass per area (LMA, g m(-2)) is an essential trait for modeling canopy function due to its strong association with photosynthesis, respiration and leaf nitrogen. Leaf mass per area, which is influenced by both leaf thickness and density (LMA = thickness × density), generally increases from the bottom to the top of tree canopies, yet the mechanisms behind this universal pattern are not yet resolved. For decades, the light environment was assumed to be the most influential driver of within-canopy variation in LMA, yet recent evidence has shown hydrostatic gradients to be more important in upper canopy positions, especially in tall evergreen trees in temperate and tropical forests. The aim of this study was to disentangle the importance of various environmental drivers on vertical LMA gradients in a mature sugar maple (Acer saccharum Marshall) forest. We compared LMA, leaf density and leaf thickness relationships with height, light and predawn leaf water potential (ΨPre) within a closed and an exposed canopy to assess leaf morphological traits at similar heights but different light conditions. Contrary to our expectations and recent findings in the literature, we found strong evidence that light was the primary driver of vertical gradients in leaf morphology. At similar heights (13-23 m), LMA was greater within the exposed canopy than the closed canopy, and light had a stronger influence over LMA compared with ΨPre. Light also had a stronger influence over both leaf thickness and density compared with ΨPre; however, the increase in LMA within both canopy types was primarily due to increasing leaf thickness with increasing light availability. This study provides strong evidence that canopy structure and crown exposure, in addition to height, should be considered as a parameter for determining vertical patterns in LMA and modeling canopy function.
Acoustic vibrations of metal nano-objects: Time-domain investigations
NASA Astrophysics Data System (ADS)
Crut, Aurélien; Maioli, Paolo; Del Fatti, Natalia; Vallée, Fabrice
2015-01-01
Theoretical and time-domain experimental investigations of the vibrational acoustic response of nano-objects are described focusing on metallic ones. Acoustic vibrations are modeled using a macroscopic-like approach based on continuum mechanics with the proper boundary conditions, a model which yields results in excellent agreement with the experimental ones and those of atomistic calculations, down to the nanometric scale. Vibrational mode excitation and detection mechanisms and the associated mode selection in ultrafast pump-probe spectroscopy are discussed, and the measured time-dependent signals in single and ensemble of nanoparticles modeled. The launched modes, their period and their damping rate are compared to experimental results obtained on ensembles of nano-objects with different composition, morphology and environment, and with size ranging from one to hundreds of nanometers. Recent extension of time-domain spectroscopy to individual nano-objects has shed new light on the vibrational responses of isolated nanoparticles, in particular on their damping, but also raises questions on the origin of its large particle to particle dispersion.
NASA Astrophysics Data System (ADS)
Näyhä, Simo; Rintamäki, Hannu; Donaldson, Gavin; Hassi, Juhani; Jousilahti, Pekka; Laatikainen, Tiina; Jaakkola, Jouni J. K.; Ikäheimo, Tiina M.
2017-04-01
The prevalence of heat-related cardiorespiratory symptoms among vulnerable groups is not well known. We therefore estimated the prevalence of heat-related cardiorespiratory symptoms among the Finnish population and their associations with social and individual vulnerability factors. The data came from the National FINRISK 2007 Study, in which 4007 men and women aged 25-74 answered questions on heat-related cardiorespiratory symptoms in the Oulu Cold and Heat Questionnaire 2007. Logistic regression was used to calculate odds ratios (ORs), their 95 % confidence intervals (CIs), and model-predicted prevalence figures. The prevalence of heat-related cardiorespiratory symptoms was 12 %. It increased with age, from 3 % at the age of 25 years to 28 % at the age of 75 years. The symptoms were associated with pre-existing lung (OR 3.93; CI 3.01-5.13) and cardiovascular diseases (OR 2.27; 1.78-2.89); being a pensioner (OR 2.91; 1.65-5.28), unemployed (OR 2.82; 1.47-5.48), or working in agriculture (OR 2.27; 1.14-4.46) compared with working in industry; having only basic vs academic education (OR 1.98; 1.31-3.05); being female (OR 1.94; 1.51-2.50); being heavy vs light alcohol consumer (OR 1.89; 1.02-3.32); undertaking hard vs light physical work (OR 1.48;1.06-2.07); and being inactive vs active in leisure time (OR 1.97; 1.39-2.81). The adjusted prevalence of symptoms showed a wide range of variation, from 3 to 61 % depending on sex, age, professional field, education, and pre-existing lung and cardiovascular diseases. In conclusion, heat-related cardiorespiratory symptoms are commonly perceived among people with pre-existing lung or cardiovascular disease, agricultural workers, unemployed, pensioners, and people having only basic education. This information is needed for any planning and targeting measures to reduce the burden of summer heat.
Light-driven photosensitizer uptake increases Candida albicans photodynamic inactivation.
Romano, Renan A; Pratavieira, Sebastião; Silva, Ana P da; Kurachi, Cristina; Guimarães, Francisco E G
2017-11-01
Photodynamic Inactivation (PDI) is based on the use of a photosensitizer (PS) and light that results mainly in the production of reactive oxygen species, aiming to produce microorganism cell death. PS incubation time and light dose are key protocol parameters that influence PDI response; the correct choice of them can increase the efficiency of inactivation. The results of this study show that a minor change in the PDI protocol, namely light-driven incubation leads to a higher photosensitizer and more uniform cell uptake inside the irradiated zone. Furthermore, as the uptake increases, the damage caused by PDI also increases. The proposed light-driven incubation prior to the inactivation illumination dose has advantages when compared to the traditional PDI treatments since it can be more selective and effective. Using a violet light as pre-illumination (light-driven incubation) source and a red-light system as PDI source, it was possible to demonstrate that when compared to the traditional protocol of dark incubation, the pre-illuminated cell culture showed an inactivation increase of 7 log units. These in vitro results performed in Candida albicans cells may result in the introduction of a new protocol for PDI. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
lcps: Light curve pre-selection
NASA Astrophysics Data System (ADS)
Schlecker, Martin
2018-05-01
lcps searches for transit-like features (i.e., dips) in photometric data. Its main purpose is to restrict large sets of light curves to a number of files that show interesting behavior, such as drops in flux. While lcps is adaptable to any format of time series, its I/O module is designed specifically for photometry of the Kepler spacecraft. It extracts the pre-conditioned PDCSAP data from light curves files created by the standard Kepler pipeline. It can also handle csv-formatted ascii files. lcps uses a sliding window technique to compare a section of flux time series with its surroundings. A dip is detected if the flux within the window is lower than a threshold fraction of the surrounding fluxes.
The Contribution of Pre-impact Spine Posture on Human Body Model Response in Whole-body Side Impact.
Poulard, David; Subit, Damien; Donlon, John-Paul; Lessley, David J; Kim, Taewung; Park, Gwansik; Kent, Richard W
2014-11-01
The objective of the study was to analyze independently the contribution of pre-impact spine posture on impact response by subjecting a finite element human body model (HBM) to whole-body, lateral impacts. Seven postured models were created from the original HBM: one matching the standard driving posture and six matching pre-impact posture measured for each of six subjects tested in previously published experiments. The same measurements as those obtained during the experiments were calculated from the simulations, and biofidelity metrics based on signals correlation were established to compare the response of HBM to that of the cadavers. HBM responses showed good correlation with the subject response for the reaction forces, the rib strain (correlation score=0.8) and the overall kinematics. The pre-impact posture was found to greatly alter the reaction forces, deflections and the strain time histories mainly in terms of time delay. By modifying only the posture of HBM, the variability in the impact response was found to be equivalent to that observed in the experiments performed with cadavers with different anthropometries. The patterns observed in the responses of the postured HBM indicate that the inclination of the spine in the frontal plane plays a major role. The postured HBM sustained from 2 to 5 bone fractures, including the scapula in some cases, confirming that the pre-impact posture influences the injury outcome predicted by the simulation.
A Saccade Based Framework for Real-Time Motion Segmentation Using Event Based Vision Sensors
Mishra, Abhishek; Ghosh, Rohan; Principe, Jose C.; Thakor, Nitish V.; Kukreja, Sunil L.
2017-01-01
Motion segmentation is a critical pre-processing step for autonomous robotic systems to facilitate tracking of moving objects in cluttered environments. Event based sensors are low power analog devices that represent a scene by means of asynchronous information updates of only the dynamic details at high temporal resolution and, hence, require significantly less calculations. However, motion segmentation using spatiotemporal data is a challenging task due to data asynchrony. Prior approaches for object tracking using neuromorphic sensors perform well while the sensor is static or a known model of the object to be followed is available. To address these limitations, in this paper we develop a technique for generalized motion segmentation based on spatial statistics across time frames. First, we create micromotion on the platform to facilitate the separation of static and dynamic elements of a scene, inspired by human saccadic eye movements. Second, we introduce the concept of spike-groups as a methodology to partition spatio-temporal event groups, which facilitates computation of scene statistics and characterize objects in it. Experimental results show that our algorithm is able to classify dynamic objects with a moving camera with maximum accuracy of 92%. PMID:28316563
A Preliminary Study of the Safety of Red Light Phototherapy of Tissues Harboring Cancer
Stadler, Istvan; Brondon, Philip; Axe, David R.; Friedman, Mark; Nardia, Frances Barg; Lanzafame, Raymond
2012-01-01
Abstract Objective: Red light phototherapy is known to stimulate cell proliferation in wound healing. This study investigated whether low-level light therapy (LLLT) would promote tumor growth when pre-existing malignancy is present. Background data: LLLT has been increasingly used for numerous conditions, but its use in cancer patients, including the treatment of lymphedema or various unrelated comorbidities, has been withheld by practitioners because of the fear that LLLT might result in initiation or promotion of metastatic lesions or new primary tumors. There has been little scientific study of oncologic outcomes after use of LLLT in cancer patients. Methods: A standard SKH mouse nonmelanoma UV-induced skin cancer model was used after visible squamous cell carcinomas were present, to study the effects of LLLT on tumor growth. The red light group (n=8) received automated full body 670 nm LLLT delivered twice a day at 5 J/cm2 using an LED source. The control group (n=8) was handled similarly, but did not receive LLLT. Measurements on 330 tumors were conducted for 37 consecutive days, while the animals received daily LLLT. Results: Daily tumor measurements demonstrated no measurable effect of LLLT on tumor growth. Conclusions: This experiment suggests that LLLT at these parameters may be safe even when malignant lesions are present. Further studies on the effects of photoirradiation on neoplasms are warranted. PMID:22853435
Zhao, Zhao; Sun, Tao; Jiang, Yun; Wu, Lijiang; Cai, Xiangzhong; Sun, Xiaodong; Sun, Xiangjun
2014-12-01
Blue light induced oxidative damage and ER stress are related to the pathogenesis of age-related macular degeneration (AMD). However, the mechanism of blue light-induced damage remained obscure. The objective of this work is to assess the photooxidative damage to retinal pigment epithelial cells (RPE) and oxidation-induced changes in expression of ER stress associated apoptotic proteins, and investigate the mechanism underlying the protective effects of grape skin extracts. To mimic lipofuscin-mediated photooxidation in vivo, ARPE-19 cells that accumulated A2E, one of lipofuscin fluorophores, were used as a model system to investigate the mechanism of photooxidative damage and the protective effects of grape skin polyphenols. Exposure of A2E containing ARPE-19 cells to blue light resulted in significant apoptosis and increases in levels of GRP78, CHOP, p-JNK, Bax, cleaved caspase-9, and cleaved caspase-3, indicating that photooxidative damage to RPE cells is mediated by the ER-stress-induced intrinsic apoptotic pathway. Cells in which GRP78 had been knocked down with shRNA were more vulnerable to photooxidative damage. Pre-treatment of blue-light-exposed A2E containing ARPE-19 cells, with grape skin extracts, inhibited apoptosis, in a dose dependent manner. Knockdown GRP78 blocked the protective effect of grape skin extracts.
R CORONAE BOREALIS STARS ARE VIABLE FACTORIES OF PRE-SOLAR GRAINS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Karakas, Amanda I.; Ruiter, Ashley J.; Hampel, Melanie, E-mail: amanda.karakas@anu.edu.au
2015-08-20
We present a new theoretical estimate for the birthrate of R Coronae Borealis (RCB) stars that is in agreement with recent observational data. We find the current Galactic birthrate of RCB stars to be ≈25% of the Galactic rate of Type Ia supernovae, assuming that RCB stars are formed through the merger of carbon–oxygen and helium-rich white dwarfs. Our new RCB birthrate (1.8 × 10{sup −3} yr{sup −1}) is a factor of 10 lower than previous theoretical estimates. This results in roughly 180–540 RCB stars in the Galaxy, depending on the RCB lifetime. From the theoretical and observational estimates, wemore » calculate the total dust production from RCB stars and compare this rate to dust production from novae and born-again asymptotic giant branch (AGB) stars. We find that the amount of dust produced by RCB stars is comparable to the amounts produced by novae or born-again post-AGB stars, indicating that these merger objects are a viable source of carbonaceous pre-solar grains in the Galaxy. There are graphite grains with carbon and oxygen isotopic ratios consistent with the observed composition of RCB stars, adding weight to the suggestion that these rare objects are a source of stardust grains.« less
An integer programming model for distal humerus fracture fixation planning.
Maratt, Joseph D; Peaks, Ya-Sin A; Doro, Lisa Case; Karunakar, Madhav A; Hughes, Richard E
2008-05-01
To demonstrate the feasibility of an integer programming model to assist in pre-operative planning for open reduction and internal fixation of a distal humerus fracture. We describe an integer programming model based on the objective of maximizing the reward for screws placed while satisfying the requirements for sound internal fixation. The model maximizes the number of bicortical screws placed while avoiding screw collision and favoring screws of greater length that cross multiple fracture planes. The model was tested on three types of total articular fractures of the distal humerus. Solutions were generated using 5, 9, 21 and 33 possible screw orientations per hole. Solutions generated using 33 possible screw orientations per hole and five screw lengths resulted in the most clinically relevant fixation plan and required the calculation of 1,191,975 pairs of screws that resulted in collision. At this level of complexity, the pre-processor took 104 seconds to generate the constraints for the solver, and a solution was generated in under one minute in all three cases. Despite the large size of this problem, it can be solved in a reasonable amount of time, making use of the model practical in pre-surgical planning.
Santos, Luis; Fernandez-Rio, Javier; Winge, Kristian; Barragán-Pérez, Beatriz; González-Gómez, Lucía; Rodríguez-Pérez, Vicente; González-Díez, Vicente; Lucía, Alejandro; Iglesias-Soler, Eliseo; Dopico-Calvo, Xurxo; Fernández-Del-Olmo, Miguel; Del-Valle, Miguel; Blanco-Traba, Miguel; Suman, Oscar E; Rodríguez-Gómez, Javier
2017-10-01
Progressive resistance exercise (PRE) can have a positive effect in individuals with Parkinson's disease (PD). However, the effect of PRE may vary with the clinical subtype of PD. To date, no study has assessed the effects of PRE in the different subtypes of PD. The aim of the present study was to assess the effects of PRE in PD patients with akinesia and rigidity (AR-subtype). A randomized controlled trial was conducted. Outpatients clinics of the Bierzo Parkinson Association (Ponferrada, Spain) and the Asturias Parkinson Association (Oviedo, Spain). Twenty-eight patients with AR-subtype PD were randomized into an Experimental Group (EG, N.=13) and Control Group (CG, N.=15). Static posturography (Centre of Pressure -CoP- parameters), gait (the Ten-Meter Walk Test [TMWT]), freezing of gait (the Freezing of Gait Questionnaire [FOG-Q]), the motor portion of the Movement Disorders Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) and patient-perceived quality of life (the 39-item Parkinson's disease Questionnaire [PDQ39]), were assessed at pre-test, post-test, and re-test. Ratings of perceived exertion (RPE) (Borg >6-20 Scale) were recorded at the end of each PRE training session. The EG displayed significant ameliorations in Length (CoP parameters) from pre- to post-test (P=0.048), in speed of fast rhythm walking (TMWT) from pre- to post-test (P=0.000), and from pre- to re-test (P=0.027), and in the PDQ39 Score from pre- to post-test (P=0.024). No significant differences were detected in Area or Speed (CoP parameters), speed of preferred rhythm walking (TMWT), FOG-Q scores, or the motor portion of the MDS-UPDRS scores. The EG reported a mean RPE of 9.95 (between "very light" and "fairly light") for the whole training program. These findings provide support for the use of PRE training in the rehabilitation of individuals with AR-subtype PD, as it can improve static posturography, gait, and quality of life. Furthermore, RPE scores showed that individuals with AR-subtype PD consider that PRE training require only light efforts. The PRE training can be a helpful and fruitful rehabilitation tool for AR-subtype PD patients.
ERIC Educational Resources Information Center
Beer, Christopher P.
2010-01-01
This study analyzes the nature of pre-service teachers' conceptual models of various electromagnetic phenomena, specifically electrical current, electrical resistance, and light/matter interactions. This is achieved through the students answering the three questions on electromagnetism using a free response approach including both verbal and…
The Baumot BA-B Diesel Particulate Filter with Pre-Catalyst is a diesel engine retrofit device for light, medium, and heavy heavy-duty diesel on-highway engines for use with commercial ultra-low-sulfur diesel (ULSD) fuel. The BA-B particulate filter is composed of a pre-catalyst ...
Pre-cataract surgery test using speckle pattern
NASA Astrophysics Data System (ADS)
Jutamulia, Suganda; Wihardjo, Erning; Widjaja, Joewono
2016-11-01
A laser diode device for pre cataract surgery test is proposed. The operation is based on the speckle generated on the retina by the cataract lens, when the cataract lens is illuminated with a coherent laser light.
Hu, Xiao-Long; Wang, Hong; Zhang, Xi-Chun
2015-01-01
We fabricated GaN-based light-emitting diodes (LEDs) without pre-activation of p-type GaN. During the fabrication process, a 100-nm-thick indium tin oxide film was served as the p-type contact layer and annealed at 500°C in N2 ambient for 20 min to increase its transparency as well as to activate the p-type GaN. The electrical measurements showed that the LEDs were featured by a lower forward voltage and higher wall-plug efficiency in comparison with LEDs using pre-activation of p-type GaN. We discussed the mechanism of activation of p-type GaN at 500°C in N2 ambient. Furthermore, x-ray photoemission spectroscopy examinations were carried out to study the improved electrical performances of the LEDs without pre-activation of p-type GaN.
NASA Astrophysics Data System (ADS)
Tatsumi, Yuki; Saito, Riichiro
2018-03-01
Raman spectra of graphene and MoS2 are calculated for incident and scattered circularly polarized light. In the case of graphene, the well known G -band Raman spectra have a not well known property that the helicity of the incident circularly polarized light changes to another helicity in the scattered light. Using the electron-photon and electron-phonon matrix elements by first-principles calculation, we calculate resonant Raman spectra of graphene and MoS2 for circularly polarized light which are compared with recent experiments. The Raman intensity for circularly polarized light is relevant to optical valley polarization in the case of MoS2. We also discuss how the helicity-selection rule can be modified by applying stress to graphene.
Blum, Thomas; Chowdhury, Saumitra; Hayakawa, Masashi; Izubuchi, Taku
2015-01-09
The most compelling possibility for a new law of nature beyond the four fundamental forces comprising the standard model of high-energy physics is the discrepancy between measurements and calculations of the muon anomalous magnetic moment. Until now a key part of the calculation, the hadronic light-by-light contribution, has only been accessible from models of QCD, the quantum description of the strong force, whose accuracy at the required level may be questioned. A first principles calculation with systematically improvable errors is needed, along with the upcoming experiments, to decisively settle the matter. For the first time, the form factor that yields the light-by-light scattering contribution to the muon anomalous magnetic moment is computed in such a framework, lattice QCD+QED and QED. A nonperturbative treatment of QED is used and checked against perturbation theory. The hadronic contribution is calculated for unphysical quark and muon masses, and only the diagram with a single quark loop is computed for which statistically significant signals are obtained. Initial results are promising, and the prospect for a complete calculation with physical masses and controlled errors is discussed.
Back-illuminate fiber system research for multi-object fiber spectroscopic telescope
NASA Astrophysics Data System (ADS)
Zhou, Zengxiang; Liu, Zhigang; Hu, Hongzhuan; Wang, Jianping; Zhai, Chao; Chu, Jiaru
2016-07-01
In the telescope observation, the position of fiber will highly influence the spectra efficient input in the fiber to the spectrograph. When the fibers were back illuminated on the spectra end, they would export light on the positioner end, so the CCD cameras could capture the photo of fiber tip position covered the focal plane, calculates the precise position information by light centroid method and feeds back to control system. A set of fiber back illuminated system was developed which combined to the low revolution spectro instruments in LAMOST. It could provide uniform light output to the fibers, meet the requirements for the CCD camera measurement. The paper was introduced the back illuminated system design and different test for the light resource. After optimization, the effect illuminated system could compare with the integrating sphere, meet the conditions of fiber position measurement.Using parallel controlled fiber positioner as the spectroscopic receiver is an efficiency observation system for spectra survey, has been used in LAMOST recently, and will be proposed in CFHT and rebuilt telescope Mayall. In the telescope observation, the position of fiber will highly influence the spectra efficient input in the fiber to the spectrograph. When the fibers were back illuminated on the spectra end, they would export light on the positioner end, so the CCD cameras could capture the photo of fiber tip position covered the focal plane, calculates the precise position information by light centroid method and feeds back to control system. After many years on these research, the back illuminated fiber measurement was the best method to acquire the precision position of fibers. In LAMOST, a set of fiber back illuminated system was developed which combined to the low revolution spectro instruments in LAMOST. It could provide uniform light output to the fibers, meet the requirements for the CCD camera measurement and was controlled by high-level observation system which could shut down during the telescope observation. The paper was introduced the back illuminated system design and different test for the light resource. After optimization, the effect illuminated system could compare the integrating sphere, meet the conditions of fiber position measurement.
Optimization of torque on an optically driven micromotor by manipulation of the index of refraction
NASA Astrophysics Data System (ADS)
Wing, Frank M., III; Mahajan, Satish; Collett, Walter
2004-12-01
Since the 1970"s, the focused laser beam has become a familiar tool to manipulate neutral, dielectric micro-objects. A number of authors, including Higurashi and Gauthier, have described the effects of radiation pressure from laser light on microrotors. Collett, et al. developed a wave, rather than a ray optic, approach in the calculation of such forces on a microrotor for the first time. This paper describes a modification to the design of a laser driven, radiation pressure microrotor, intended to improve the optically generated torque. Employing the wave approach, the electric and magnetic fields in the vicinity of the rotor are calculated using the finite difference time domain (FDTD) method, which takes into account the wave nature of the incident light. Forces are calculated from the application of Maxwell"s stress tensor over the surfaces of the rotor. Results indicate a significant increase in torque when the index of refraction of the microrotor is changed from a single value to an inhomogeneous profile. The optical fiber industry has successfully employed a variation in the index of refraction across the cross section of a fiber for the purpose of increasing the efficiency of light transmission. Therefore, it is hoped that various fabrication methods can be utilized for causing desired changes in the index of refraction of an optically driven microrotor. Various profiles of the index of refraction inside a microrotor are considered for optimization of torque. Simulation methodology and results of torque on a microrotor for various profiles of the index of refraction are presented. Guidelines for improvised fabrication of efficient microrotors may then be obtained from these profiles.
A new calculation of LAMOST optical vignetting
NASA Astrophysics Data System (ADS)
Li, Shuang; Luo, Ali; Chen, Jianjun; Liu, Genrong; Comte, Georges
2012-09-01
A new method to calculate the optical vignetting of LAMOST (Large Sky Area Muti-Object Fiber Spectroscopic Telescope) is presented. With the pilot survey of LAMOST, it is necessary to have thorough and quantitative estimation and analysis on the observing efficiency which is affected by various factors: the optical system of the telescope and the spectrograph that is vignetting, the focal instrument, and the site condition. The wide field and large pupil of LAMOST fed by a Schmidt reflecting mirror, with a fixed optical axis coinciding with the local polar axis, lead to significant telescope vignetting, caused by the effective light-collecting area of the corrector, the light obstruction of the focal-plate, and the size of the primary mirror. A calculation of the vignetting has been presented by Xue et al. (2007), which considered 4 meter circle limitation and based on ray-tracking. In fact, there is no effect of the 4 meter circle limitation, so that we compute the vignetting again by means of obtaining the ratio of effective projected area of the corrector. All the results are derived by AUTOCAD. Moreover, the vignetting functions and vignetting variations with declination at which the telescope is pointed and the position considered in the focal surface are presented and analysed. Finally, compared with the ray-tracing method to obtain the vignetting before, the validity and availability of the proposed method are illustrated.
Morin, Jean-François; Botton, Eléonore; Jacquemard, François; Richard-Gireme, Anouk
2013-01-01
The Fetal medicine foundation (FMF) has developed a new algorithm called Prenatal Risk Calculation (PRC) to evaluate Down syndrome screening based on free hCGβ, PAPP-A and nuchal translucency. The peculiarity of this algorithm is to use the degree of extremeness (DoE) instead of the multiple of the median (MoM). The biologists measuring maternal seric markers on Kryptor™ machines (Thermo Fisher Scientific) use Fast Screen pre I plus software for the prenatal risk calculation. This software integrates the PRC algorithm. Our study evaluates the data of 2.092 patient files of which 19 show a fœtal abnormality. These files have been first evaluated with the ViewPoint software based on MoM. The link between DoE and MoM has been analyzed and the different calculated risks compared. The study shows that Fast Screen pre I plus software gives the same risk results as ViewPoint software, but yields significantly fewer false positive results.
Detecting Lateral Motion using Light’s Orbital Angular Momentum
Cvijetic, Neda; Milione, Giovanni; Ip, Ezra; Wang, Ting
2015-01-01
Interrogating an object with a light beam and analyzing the scattered light can reveal kinematic information about the object, which is vital for applications ranging from autonomous vehicles to gesture recognition and virtual reality. We show that by analyzing the change in the orbital angular momentum (OAM) of a tilted light beam eclipsed by a moving object, lateral motion of the object can be detected in an arbitrary direction using a single light beam and without object image reconstruction. We observe OAM spectral asymmetry that corresponds to the lateral motion direction along an arbitrary axis perpendicular to the plane containing the light beam and OAM measurement axes. These findings extend OAM-based remote sensing to detection of non-rotational qualities of objects and may also have extensions to other electromagnetic wave regimes, including radio and sound. PMID:26493681
GOETZINGER, Katherine R.; ZHONG, Yan; CAHILL, Alison G.; ODIBO, Linda; MACONES, George A.; ODIBO, Anthony O.
2014-01-01
Objective To estimate the efficiency of first-trimester uterine artery Doppler, A-disintegrin and metalloprotease 12 (ADAM12), pregnancy-associated plasma protein A (PAPP-A) and maternal characteristics in the prediction of pre-eclampsia. Methods This is a prospective cohort study of patients presenting for first-trimester aneuploidy screening between 11-14 weeks’ gestation. Maternal serum ADAM12 and PAPP-A levels were measured by immunoassay, and mean uterine artery Doppler pulsatility indices (PI) were calculated. Outcomes of interest included pre-eclampsia, early pre-eclampsia, defined as requiring delivery at <34 weeks’ gestation, and gestational hypertension. Logistic regression analysis was used to model the prediction of pre-eclampsia using ADAM12 multiples of the median (MoM), PAPP-A MoM, and uterine artery Doppler PI MoM, either individually or in combination. Sensitivity, specificity, and area under the receiver-operating characteristic curves (AUC) were used to compare the screening efficiency of the models using non-parametric U-statistics. Results Of 578 patients with complete outcome data, there were 54 (9.3%) cases of preeclampsia and 13 (2.2%) cases of early pre-eclampsia. Median ADAM12 levels were significantly lower in patients who developed pre-eclampsia compared to those who did not. (0.81 v. 1.01 MoMs; p<0.04) For a fixed false positive rate (FPR) of 10%, ADAM12, PAPP-A, and uterine artery Doppler in combination with maternal characteristics identified 50%, 48%, and 52% of patients who developed pre-eclampsia, respectively. Combining these first-trimester parameters did not improve the predictive efficiency of the models. Conclusion First-trimester ADAM12, PAPP-A, and uterine artery Doppler are not sufficiently predictive of pre-eclampsia. Combinations of these parameters do not further improve their screening efficiency. PMID:23980220
EDITORIAL: Transformation optics Transformation optics
NASA Astrophysics Data System (ADS)
Shalaev, Vladimir M.; Pendry, John
2011-02-01
Metamaterials are artificial materials with versatile properties that can be tailored to fit almost any practical need and thus go well beyond what can be obtained with `natural' materials. Recent progress in developing optical metamaterials allows unprecedented extreme control over the flow of light at both the nano- and macroscopic scales. The innovative field of transformation optics, which is enabled by metamaterials, inspired researchers to take a fresh look at the very foundations of optics and helped to create a new paradigm for the science of light. Similar to general relativity, where time and space are curved, transformation optics shows that the space for light can also be bent in an almost arbitrary way. Most importantly, the optical space can be designed and engineered, opening up the fascinating possibility of controlling the flow of light with nanometer spatial precision. This new paradigm enables a number of novel optical devices guiding how, using metamaterials, the space for light can be curved in a pre-designed and well-controlled way. Metamaterials which incorporate the innovative theories of transformation optics are pertinent to the important areas of optical cloaking, optical black holes, super-resolution imaging, and other sci-fi-like devices. One such exciting device is an electromagnetic cloak that can bend light around itself, similar to the flow of water around a stone, making invisible both the cloak and the object hidden inside. Another important application is a flat hyperlens that can magnify the nanometer-scale features of an object that cannot be resolved with conventional optics. This could revolutionize the field of optical imaging, for instance, because such a meta-lens could become a standard add-on tool for microscopes. By enabling nanoscale resolution in optical microscopy, metamaterial-based transformation optics could allow one to literally see extremely small objects with the eye, including biological cells, viruses, and possibly even DNA molecules. Light-concentrating devices, such as the optical black hole, can be used for efficient solar light collection in photovoltaic elements for renewable energy. With the dramatic advances in micro- and nanofabrication methods, we are presented with the opportunity to control light in a way that was not possible with the materials provided to us by nature. In an artificial pattern of sub-wavelength elements, the propagation of electromagnetic energy can be defined by an equivalent spatial and spectral dispersion of effective dielectric and magnetic properties. These synthetic structures, which can be fabricated with a desired spatial distribution of effective permittivity epsilon(r) and permeability μ(r), offer a unique potential to guide and control the flow of electromagnetic energy in such an engineered optical space. No longer are we constrained by the electromagnetic response of natural materials and their chemical compounds. Instead, we can tailor the shape and size of the structural units of the metamaterials, or tune their composition and morphology to provide new functionality.
batman: BAsic Transit Model cAlculatioN in Python
NASA Astrophysics Data System (ADS)
Kreidberg, Laura
2015-11-01
I introduce batman, a Python package for modeling exoplanet transit light curves. The batman package supports calculation of light curves for any radially symmetric stellar limb darkening law, using a new integration algorithm for models that cannot be quickly calculated analytically. The code uses C extension modules to speed up model calculation and is parallelized with OpenMP. For a typical light curve with 100 data points in transit, batman can calculate one million quadratic limb-darkened models in 30 seconds with a single 1.7 GHz Intel Core i5 processor. The same calculation takes seven minutes using the four-parameter nonlinear limb darkening model (computed to 1 ppm accuracy). Maximum truncation error for integrated models is an input parameter that can be set as low as 0.001 ppm, ensuring that the community is prepared for the precise transit light curves we anticipate measuring with upcoming facilities. The batman package is open source and publicly available at https://github.com/lkreidberg/batman .
Ambient lighting: setting international standards for the viewing of softcopy chest images
NASA Astrophysics Data System (ADS)
McEntee, Mark F.; Ryan, John; Evanoff, Micheal G.; Keeling, Aoife; Chakraborty, Dev; Manning, David; Brennan, Patrick C.
2007-03-01
Clinical radiological judgments are increasingly being made on softcopy LCD monitors. These monitors are found throughout the hospital environment in radiological reading rooms, outpatient clinics and wards. This means that ambient lighting where clinical judgments from images are made can vary widely. Inappropriate ambient lighting has several deleterious effects: monitor reflections reduce contrast; veiling glare adds brightness; dynamic range and detectability of low contrast objects is limited. Radiological images displayed on LCDs are more sensitive to the impact of inappropriate ambient lighting and with these devices problems described above are often more evident. The current work aims to provide data on optimum ambient lighting, based on lesions within chest images. The data provided may be used for the establishment of workable ambient lighting standards. Ambient lighting at 30cms from the monitor was set at 480 Lux (office lighting) 100 Lux (WHO recommendations), 40 Lux and <10 Lux. All monitors were calibrated to DICOM part 14 GSDF. Sixty radiologists were presented with 30 chest images, 15 images having simulated nodular lesions of varying subtlety and size. Lesions were positioned in accordance with typical clinical presentation and were validated radiologically. Each image was presented for 30 seconds and viewers were asked to identify and score any visualized lesion from 1-4 to indicate confidence level of detection. At the end of the session, sensitivity and specificity were calculated. Analysis of the data suggests that visualization of chest lesions is affected by inappropriate lighting with chest radiologists demonstrating greater ambient lighting dependency. JAFROC analyses are currently being performed.
Appearance-based face recognition and light-fields.
Gross, Ralph; Matthews, Iain; Baker, Simon
2004-04-01
Arguably the most important decision to be made when developing an object recognition algorithm is selecting the scene measurements or features on which to base the algorithm. In appearance-based object recognition, the features are chosen to be the pixel intensity values in an image of the object. These pixel intensities correspond directly to the radiance of light emitted from the object along certain rays in space. The set of all such radiance values over all possible rays is known as the plenoptic function or light-field. In this paper, we develop a theory of appearance-based object recognition from light-fields. This theory leads directly to an algorithm for face recognition across pose that uses as many images of the face as are available, from one upwards. All of the pixels, whichever image they come from, are treated equally and used to estimate the (eigen) light-field of the object. The eigen light-field is then used as the set of features on which to base recognition, analogously to how the pixel intensities are used in appearance-based face and object recognition.
Pre-scission model predictions of fission fragment mass distributions for super-heavy elements
NASA Astrophysics Data System (ADS)
Carjan, N.; Ivanyuk, F. A.; Oganessian, Yu. Ts.
2017-12-01
The total deformation energy just before the moment of neck rupture for the heaviest nuclei for which spontaneous fission has been detected (Ds281279-, 281Rg and Cn284282-) is calculated. The Strutinsky's prescription is used and nuclear shapes just before scission are described in terms of Cassinian ovals defined for the fixed value of elongation parameter α = 0.98 and generalized by the inclusion of four additional shape parameters: α1, α3, α4, and α6. Supposing that the probability of each point in the deformation space is given by Boltzmann factor, the distribution of the fission-fragment masses is estimated. The octupole deformation α3 at scission is found to play a decisive role in determining the main feature of the mass distribution: symmetric or asymmetric. Only the inclusion of α3 leads to an asymmetric division. Finally, the calculations are extended to an unexplored region of super-heavy nuclei: the even-even Fl (Z = 114), Lv (Z = 116), Og (Z = 118) and (Z = 126) isotopes. For these nuclei, the most probable mass of the light fragment has an almost constant value (≈136) like in the case of the most probable mass of the heavy fragment in the actinide region. It is the neutron shell at 82 that makes this light fragment so stable. Naturally, for very neutron-deficient isotopes, the mass division becomes symmetric when N = 2 × 82.
Seidman, Dominika L; Weber, Shannon; Cohan, Deborah
2017-01-01
Abstract Introduction: HIV prevention during pregnancy and lactation is critical for both maternal and child health. Pregnancy provides a critical opportunity for clinicians to elicit women’s vulnerabilities to HIV and offer HIV testing, treatment and referral and/or comprehensive HIV prevention options for the current pregnancy, the postpartum period and safer conception options for future pregnancies. In this commentary, we review the safety of oral pre-exposure prophylaxis with tenofovir/emtricitabine in pregnant and lactating women and suggest opportunities to identify pregnant and postpartum women at substantial risk of HIV. We then describe a clinical approach to caring for women who both choose and decline pre-exposure prophylaxis during pregnancy and postpartum, highlighting areas for future research. Discussion: Evidence suggests that pre-exposure prophylaxis with tenofovir/emtricitabine is safe in pregnancy and lactation. Identifying women vulnerable to HIV and eligible for pre-exposure prophylaxis is challenging in light of the myriad of individual, community, and structural forces impacting HIV acquisition. Validated risk calculators exist for specific populations but have not been used to screen and offer HIV prevention methods. Partner testing and engagement of men living with HIV are additional means of reaching at-risk women. However, women’s vulnerabilities to HIV change over time. Combining screening for HIV vulnerability with HIV and/or STI testing at standard intervals during pregnancy is a practical way to prompt providers to incorporate HIV screening and prevention counselling. We suggest using shared decision-making to offer women pre-exposure prophylaxis as one of multiple HIV prevention strategies during pregnancy and postpartum, facilitating open conversations about HIV vulnerabilities, preferences about HIV prevention strategies, and choosing a method that best meets the needs of each woman. Conclusion: Growing evidence suggests that pre-exposure prophylaxis with tenofovir/emtricitabine during pregnancy and lactation is safe and effective. Shared decision-making provides one approach to identify at-risk women and offers pre-exposure prophylaxis but requires implementation research in diverse clinical settings. Including pregnant and breastfeeding women in future HIV prevention research is critical for the creation of evidence-driven public health policies and clinical guidelines. PMID:28361503
Seidman, Dominika L; Weber, Shannon; Cohan, Deborah
2017-03-08
HIV prevention during pregnancy and lactation is critical for both maternal and child health. Pregnancy provides a critical opportunity for clinicians to elicit women's vulnerabilities to HIV and offer HIV testing, treatment and referral and/or comprehensive HIV prevention options for the current pregnancy, the postpartum period and safer conception options for future pregnancies. In this commentary, we review the safety of oral pre-exposure prophylaxis with tenofovir/emtricitabine in pregnant and lactating women and suggest opportunities to identify pregnant and postpartum women at substantial risk of HIV. We then describe a clinical approach to caring for women who both choose and decline pre-exposure prophylaxis during pregnancy and postpartum, highlighting areas for future research. Evidence suggests that pre-exposure prophylaxis with tenofovir/emtricitabine is safe in pregnancy and lactation. Identifying women vulnerable to HIV and eligible for pre-exposure prophylaxis is challenging in light of the myriad of individual, community, and structural forces impacting HIV acquisition. Validated risk calculators exist for specific populations but have not been used to screen and offer HIV prevention methods. Partner testing and engagement of men living with HIV are additional means of reaching at-risk women. However, women's vulnerabilities to HIV change over time. Combining screening for HIV vulnerability with HIV and/or STI testing at standard intervals during pregnancy is a practical way to prompt providers to incorporate HIV screening and prevention counselling. We suggest using shared decision-making to offer women pre-exposure prophylaxis as one of multiple HIV prevention strategies during pregnancy and postpartum, facilitating open conversations about HIV vulnerabilities, preferences about HIV prevention strategies, and choosing a method that best meets the needs of each woman. Growing evidence suggests that pre-exposure prophylaxis with tenofovir/emtricitabine during pregnancy and lactation is safe and effective. Shared decision-making provides one approach to identify at-risk women and offers pre-exposure prophylaxis but requires implementation research in diverse clinical settings. Including pregnant and breastfeeding women in future HIV prevention research is critical for the creation of evidence-driven public health policies and clinical guidelines.
Curing mode affects bond strength of adhesively luted composite CAD/CAM restorations to dentin.
Lührs, Anne-Katrin; Pongprueksa, Pong; De Munck, Jan; Geurtsen, Werner; Van Meerbeek, Bart
2014-03-01
To determine the effect of curing mode and restoration-surface pre-treatment on the micro-tensile bond strength (μTBS) to dentin. Sandblasted CAD/CAM composite blocks (LAVA Ultimate, 3M ESPE) were cemented to bur-cut dentin using either the etch & rinse composite cement Nexus 3 ('NX3', Kerr) with Optibond XTR ('XTR', Kerr), or the self-etch composite cement RelyX Ultimate ('RXU', 3M ESPE) with Scotchbond Universal ('SBU', 3M ESPE). All experimental groups included different 'curing modes' (light-curing of adhesive and cement ('LL'), light-curing of adhesive and auto-cure of cement ('LA'), co-cure of adhesive through light-curing of cement ('AL'), or complete auto-cure ('AA')) and different 'restoration-surface pre-treatments' of the composite block (NX3: either a silane primer (Kerr), or the XTR adhesive; RXU: either silane primer (RelyX Ceramic Primer, 3M ESPE) and SBU, or solely SBU). After water-storage (7 days, 37°C), the μTBS was measured. Additionally, the degree of conversion (DC) of both cements was measured after 10min and after 1 week, either auto-cured (21°C/37°C) or light-cured (directly/through 3-mm CAD/CAM composite). The linear mixed-effects model (α=0.05) revealed a significant influence of the factors 'curing mode' and 'composite cement', and a less significant effect of the factor 'restoration-surface pre-treatment'. Light-curing 'LL' revealed the highest μTBS, which decreased significantly for all other curing modes. For curing modes 'AA' and 'AL', the lowest μTBS and a high percentage of pre-testing failures were reported. Overall, DC increased with light-curing and incubation time. The curing mode is decisive for the bonding effectiveness of adhesively luted composite CAD/CAM restorations to dentin. Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.
Accretion Disk Outflows from Compact Object Mergers
NASA Astrophysics Data System (ADS)
Metzger, Brian
Nuclear reactions play a key role in the accretion disks and outflows associated with the merger of binary compact objects and the central engines of gamma-ray bursts and supernovae. The proposed research program will investigate the impact of nucleosynthesis on these events and their observable signatures by means of analytic calculations and numerical simulations. One focus of this research is rapid accretion following the tidal disruption of a white dwarf (WD) by a neutron star (NS) or black hole (BH) binary companion. Tidal disruption shreds the WD into a massive torus composed of C, O, and/or He, which undergoes nuclear reactions and burns to increasingly heavier elements as it flows to smaller radii towards the central compact object. The nuclear energy so released is comparable to that released gravitationally, suggesting that burning could drastically alter the structure and stability of the accretion flow. Axisymmetric hydrodynamic simulations of the evolution of the torus including nuclear burning will be performed to explore issues such as the mass budget of the flow (accretion vs. outflows) and its thermal stability (steady burning and accretion vs. runaway explosion). The mass, velocity, and composition of outflows from the disk will be used in separate radiative transfer calculations to predict the lightcurves and spectra of the 56Ni-decay powered optical transients from WD-NS/WD-BH mergers. The possible connection of such events to recently discovered classes of sub-luminous Type I supernovae will be assessed. The coalescence of NS-NS/NS-BH binaries also results in the formation of a massive torus surrounding a central compact object. Three-dimensional magnetohydrodynamic simulations of the long-term evolution of such accretion disks will be performed, which for the first time follow the effects of weak interactions and the nuclear energy released by Helium recombination. The nucleosynthetic yield of disk outflows will be calculated using a detailed nuclear reaction network along characteristic Lagrangian trajectories. Results of these calculations will be used to (1) reassess NS-NS/NS-BH mergers as an astrophysical source of heavy r-process nuclei; and (2) calculate the light curves of the optical transients (`kilonovae') powered by the radioactive decay. Separate work will assess the effects that neutrino irradiation from a long-lived neutron star remnant has on the electron fraction of the disk outflows. The strong contrast between the opacities of proton- and neutron-rich matter imply that the presence and lifetime of such a remnant could be imprinted on the kilonova emission. Our investigation sheds light on the central engines of GRBs and other high-energy transients and hence is relevant to NASA's Swift, MAXI, and Fermi missions. Our results will also impact the interpretation of future observations of supernovae and their galactic environments with the Hubble Space Telescope (HST). Our results will also impact follow-up observations of kilonovae, maximizing the impact of HST to constrain the key open questions such as the progenitors of gamma-ray bursts and the origin of r-process nuclei.
Speckle-based three-dimensional velocity measurement using spatial filtering velocimetry.
Iversen, Theis F Q; Jakobsen, Michael L; Hanson, Steen G
2011-04-10
We present an optical method for measuring the real-time three-dimensional (3D) translational velocity of a diffusely scattering rigid object observed through an imaging system. The method is based on a combination of the motion of random speckle patterns and regular fringe patterns. The speckle pattern is formed in the observation plane of the imaging system due to reflection from an area of the object illuminated by a coherent light source. The speckle pattern translates in response to in-plane translation of the object, and the presence of an angular offset reference wave coinciding with the speckle pattern in the observation plane gives rise to interference, resulting in a fringe pattern that translates in response to the out-of-plane translation of the object. Numerical calculations are performed to evaluate the dynamic properties of the intensity distribution and the response of realistic spatial filters designed to measure the three components of the object's translational velocity. Furthermore, experimental data are presented that demonstrate full 3D velocity measurement. © 2011 Optical Society of America
MAHLI Calibration Target in Ultraviolet Light
2012-02-07
During pre-flight testing in March 2011, the Mars Hand Lens Imager MAHLI camera on NASA Mars rover Curiosity took this image of the MAHLI calibration target under illumination from MAHLI two ultraviolet LEDs light emitting diodes.
Light Pipe Energy Savings Calculator
NASA Astrophysics Data System (ADS)
Owens, Erin; Behringer, Ernest R.
2009-04-01
Dependence on fossil fuels is unsustainable and therefore a shift to renewable energy sources such as sunlight is required. Light pipes provide a way to utilize sunlight for interior lighting, and can reduce the need for fossil fuel-generated electrical energy. Because consumers considering light pipe installation may be more strongly motivated by cost considerations than by sustainability arguments, an easy means to examine the corresponding costs and benefits is needed to facilitate informed decision-making. The purpose of this American Physical Society Physics and Society Fellowship project is to create a Web-based calculator to allow users to quantify the possible cost savings for their specific light pipe application. Initial calculations show that the illumination provided by light pipes can replace electric light use during the day, and in many cases can supply greater illumination levels than those typically given by electric lighting. While the installation cost of a light pipe is significantly greater than the avoided cost of electricity over the lifetime of the light pipe at current prices, savings may be realized if electricity prices increase.
Method of measuring blood oxygenation based on spectroscopy of diffusely scattered light
NASA Astrophysics Data System (ADS)
Kleshnin, M. S.; Orlova, A. G.; Kirillin, M. Yu.; Golubyatnikov, G. Yu.; Turchin, I. V.
2017-05-01
A new approach to the measurement of blood oxygenation is developed and implemented, based on an original two-step algorithm reconstructing the relative concentration of biological chromophores (haemoglobin, water, lipids) from the measured spectra of diffusely scattered light at different distances from the radiation source. The numerical experiments and approbation of the proposed approach using a biological phantom have shown the high accuracy of the reconstruction of optical properties of the object in question, as well as the possibility of correct calculation of the haemoglobin oxygenation in the presence of additive noises without calibration of the measuring device. The results of the experimental studies in animals agree with the previously published results obtained by other research groups and demonstrate the possibility of applying the developed method to the monitoring of blood oxygenation in tumour tissues.
Problem definition for pre-crash sensing advanced restraints.
DOT National Transportation Integrated Search
2009-04-01
This report presents the results of crash analyses that defined and prioritized target crashes for advanced restraint systems based on pre-crash sensors. These analyses targeted the driver and front-seat passenger 13 or older, traveling in light vehi...
Image quality of the cat eye measured during retinal ganglion cell experiments
Bonds, A. B.; Enroth-Cugell, Christina; Pinto, L. H.
1972-01-01
1. The modulation transfer function (MTF) of the dioptrics of fifteen cat eyes was determined. The aerial image, formed by the eye of a standard object (a 0·5-1·0° annulus), was photographed. The transmission of the film negative was measured with a scanning microdensitometer to yield the light distribution within the aerial image. Correcting for the double passage, this experimentally determined light distribution and the known object light distribution were used to obtain the MTF, applying Fourier methods. Each MTF was used to calculate the light distribution within the retinal image of stimuli of various geometry used in experiments on retinal ganglion cells in the same eye. 2. When the eye was equipped with an artificial pupil of the same size as that used in the neurophysiological experiments (4·0-4·8 mm diam.) the MTF had fallen to 0·5 at 2·43 c/deg. When the pupil was removed the MTF had fallen to 0·5 at a much lower spatial frequency (1·0 c/deg). This shows that even when one uses an artificial pupil too large to provide optimal image quality there is a vast improvement over using no pupil. 3. These image quality measurements were prompted by the need to know the actual stimulus image in experiments on the functional organization of the receptive field, a need exemplified in this paper by a few specific physiological results. The full neurophysiological results appear in the next two papers. ImagesFig. 3Fig. 4 PMID:5014105
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, Zhi-Jun; Zhan, Fei; Xiao, Hongyan
X-ray transient absorption spectroscopy (XTA) and optical transient spectroscopy (OTA) were used to probe the Co(I) intermediate generated in situ from an aqueous photocatalytic hydrogen evolution system, with [RuII(bpy)3]Cl2·6H2O as the photosensitizer, ascorbic acid/ascorbate as the electron donor, and the Co-polypyridyl complex ([CoII(DPABpy) Cl]Cl) as the pre-catalyst. Upon exposure to light, the XTA measured at Co K-edge visualizes the grow and decay of the Co(I) intermediate, and reveals its Co-N bond contraction of 0.09 ± 0.03 Å. Density functional theory (DFT) calculations support the bond contraction and illustrate that the metal-to-ligand π back-bonding greatly stabilizes the penta-coordinated Co(I) intermediate, whichmore » provides easy photon access. To the best of our knowledge, this is the first example of capturing the penta-coordinated Co(I) intermediate in operando with bond contraction by XTA, thereby providing new insights for fundamental understanding of structure– function relationship of cobalt-based molecular catalysts.« less
Jin, X; Yan, H; Han, C; Zhou, Y; Yi, J
2015-01-01
Objective: To investigate comparatively the percentage gamma passing rate (%GP) of two-dimensional (2D) and three-dimensional (3D) pre-treatment volumetric modulated arc therapy (VMAT) dosimetric verification and their correlation and sensitivity with percentage dosimetric errors (%DE). Methods: %GP of 2D and 3D pre-treatment VMAT quality assurance (QA) with different acceptance criteria was obtained by ArcCHECK® (Sun Nuclear Corporation, Melbourne, FL) for 20 patients with nasopharyngeal cancer (NPC) and 20 patients with oesophageal cancer. %DE were calculated from planned dose–volume histogram (DVH) and patients' predicted DVH calculated by 3DVH® software (Sun Nuclear Corporation). Correlation and sensitivity between %GP and %DE were investigated using Pearson's correlation coefficient (r) and receiver operating characteristics (ROCs). Results: Relatively higher %DE on some DVH-based metrics were observed for both patients with NPC and oesophageal cancer. Except for 2%/2 mm criterion, the average %GPs for all patients undergoing VMAT were acceptable with average rates of 97.11% ± 1.54% and 97.39% ± 1.37% for 2D and 3D 3%/3 mm criteria, respectively. The number of correlations for 3D was higher than that for 2D (21 vs 8). However, the general correlation was still poor for all the analysed metrics (9 out of 26 for 3D 3%/3 mm criterion). The average area under the curve (AUC) of ROCs was 0.66 ± 0.12 and 0.71 ± 0.21 for 2D and 3D evaluations, respectively. Conclusions: There is a lack of correlation between %GP and %DE for both 2D and 3D pre-treatment VMAT dosimetric evaluation. DVH-based dose metrics evaluation obtained from 3DVH will provide more useful analysis. Advances in knowledge: Correlation and sensitivity of %GP with %DE for VMAT QA were studied for the first time. PMID:25494412
Gait analysis and weight bearing in pre-clinical joint pain research.
Ängeby Möller, Kristina; Svärd, Heta; Suominen, Anni; Immonen, Jarmo; Holappa, Johanna; Stenfors, Carina
2018-04-15
There is a need for better joint pain treatment, but development of new medication has not been successful. Pre-clinical models with readouts that better reflect the clinical situation are needed. In patients with joint pain, pain at rest and pain at walking are two major complaints. We describe a new way of calculating results from gait analysis using the CatWalk™ setup. Rats with monoarthritis induced by injection of Complete Freund's Adjuvant (CFA) intra-articularly into the ankle joint of one hind limb were used to assess gait and dynamic weight bearing. The results show that dynamic weight bearing was markedly reduced for the injected paw. Gait parameters such as amount of normal step sequences, walking speed and duration of step placement were also affected. Treatment with naproxen (an NSAID commonly used for inflammatory pain) attenuated the CFA-induced effects. Pregabalin, which is used for neuropathic pain, had no effect. Reduced dynamic weight bearing during locomotion, assessed and calculated in the way we present here, showed a dose-dependent and lasting normalization after naproxen treatment. In contrast, static weight bearing while standing (Incapacitance tester) showed a significant effect for a limited time only. Mechanical sensitivity (von Frey Optihairs) was completely normalized by naproxen, and the window for testing pharmacological effect disappeared. Objective and reproducible effects, with an endpoint showing face validity compared to pain while walking in patients with joint pain, are achieved by a new way of calculating dynamic weight bearing in monoarthritic rats. Copyright © 2017 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Russ, M.; Shankar, A.; Jain, A.; Setlur Nagesh, S. V.; Ionita, C. N.; Scott, C.; Karim, K. S.; Bednarek, D. R.; Rudin, S.
2016-03-01
A novel amorphous selenium (a-Se) direct detector with CMOS readout has been designed, and relative detector performance investigated. The detector features include a 25μm pixel pitch, and 1000μm thick a-Se layer operating at 10V/μm bias field. A simulated detector DQE was determined, and used in comparative calculations of the Relative Object Detectability (ROD) family of prewhitening matched-filter (PWMF) observer and non-pre-whitening matched filter (NPWMF) observer model metrics to gauge a-Se detector performance against existing high resolution micro-angiographic fluoroscopic (MAF) detectors and a standard flat panel detector (FPD). The PWMF-ROD or ROD metric compares two x-ray imaging detectors in their relative abilities in imaging a given object by taking the integral over spatial frequencies of the Fourier transform of the detector DQE weighted by an object function, divided by the comparable integral for a different detector. The generalized-ROD (G-ROD) metric incorporates clinically relevant parameters (focal- spot size, magnification, and scatter) to show the degradation in imaging performance for detectors that are part of an imaging chain. Preliminary ROD calculations using simulated spheres as the object predicted superior imaging performance by the a-Se detector as compared to existing detectors. New PWMF-G-ROD and NPWMF-G-ROD results still indicate better performance by the a-Se detector in an imaging chain over all sphere sizes for various focal spot sizes and magnifications, although a-Se performance advantages were degraded by focal spot blurring. Nevertheless, the a-Se technology has great potential to provide break- through abilities such as visualization of fine details including of neuro-vascular perforator vessels and of small vascular devices.
ERIC Educational Resources Information Center
Hatem, Neil
2010-01-01
This study investigates the relationship between the use of graphing calculators employed as Type II technology and student achievement, as determined by assessing students' problem solving skills associated with the concept of function, at the college algebra and pre-calculus level. In addition, this study explores the integration of graphing…
Rotation, scale, and translation invariant pattern recognition using feature extraction
NASA Astrophysics Data System (ADS)
Prevost, Donald; Doucet, Michel; Bergeron, Alain; Veilleux, Luc; Chevrette, Paul C.; Gingras, Denis J.
1997-03-01
A rotation, scale and translation invariant pattern recognition technique is proposed.It is based on Fourier- Mellin Descriptors (FMD). Each FMD is taken as an independent feature of the object, and a set of those features forms a signature. FMDs are naturally rotation invariant. Translation invariance is achieved through pre- processing. A proper normalization of the FMDs gives the scale invariance property. This approach offers the double advantage of providing invariant signatures of the objects, and a dramatic reduction of the amount of data to process. The compressed invariant feature signature is next presented to a multi-layered perceptron neural network. This final step provides some robustness to the classification of the signatures, enabling good recognition behavior under anamorphically scaled distortion. We also present an original feature extraction technique, adapted to optical calculation of the FMDs. A prototype optical set-up was built, and experimental results are presented.
Industrial metrology as applied to large physics experiments
DOE Office of Scientific and Technical Information (OSTI.GOV)
Veal, D.
1993-05-01
A physics experiment is a large complex 3-D object (typ. 1200 m{sup 3}, 35000 tonnes), with sub-millimetric alignment requirements. Two generic survey alignment tasks can be identified; first, an iterative positioning of the apparatus subsystems in space and, second, a quantification of as-built parameters. The most convenient measurement technique is industrial triangulation but the complexity of the measured object and measurement environment constraints frequently requires a more sophisticated approach. To enlarge the ``survey alignment toolbox`` measurement techniques commonly associated with other disciplines such as geodesy, applied geodesy for accelerator alignment, and mechanical engineering are also used. Disparate observables require amore » heavy reliance on least squares programs for campaign pre-analysis and calculation. This paper will offer an introduction to the alignment of physics experiments and will identify trends for the next generation of SSC experiments.« less
Ye, Shaodong; Yin, Lu; Amico, Rivet; Simoni, Jane; Vermund, Sten; Ruan, Yuhua; Shao, Yiming; Qian, Han-Zhu
2014-01-01
Objective To conduct a systematic review and meta-analysis to evaluate the efficacy of peer-led interventions in reducing unprotected anal intercourse (UAI) among men who have sex with men (MSM). Methods Randomized clinical trials (RCTs), quasi-experimental studies, pre- and post-intervention studies without control groups, and serial cross-sectional assessments involving peers delivering interventions among MSM and published as of February 2012 were identified by systematically searching 13 electronic databases and cross-referencing. Effect sizes (ES) were calculated as the changes of standardized mean difference (SMD) in UAI between groups or pre-post intervention. Results A total of 22 studies met the eligibility criteria, including five RCTs, six quasi-experimental studies, six pre-and-post intervention studies, and five serial cross-sectional intervention studies. We used 15 individual studies including 17 interventions for overall ES calculation; peer-led interventions reduced UAI with any sexual partners in meta-analysis (mean ES: -0.27; 95% confidence interval [CI]: −0.41, −0.13; P<0.01). Subgroup analyses demonstrated a statistically significant reduction on UAI in quasi-experimental studies (mean ES: −0.30; 95% CI: −0.50, −0.09; P = 0.01) and serial cross-sectional intervention studies (mean ES: −0.33; 95% CI: −0.57, −0.09; P = 0.01), but non-significant reduction in RCTs (mean ES: −0.15; 95% CI: −0.36, 0.07; P = 0.18) or pre- and post-intervention studies (mean ES: −0.29; 95% CI: −0.69, 0.11; P = 0.15). Heterogeneity was large across these 15 studies (I 2 = 77.5%; P<0.01), largely due to pre-and-post intervention studies and serial cross-sectional intervention studies. Conclusions Peer-led HIV prevention interventions reduced the overall UAI among MSM, but the efficacy varied by study design. More RCTs are needed to evaluate the effect of peer-led interventions while minimizing potential bias. PMID:24614809
Quantitative light-induced fluorescence technology for quantitative evaluation of tooth wear
NASA Astrophysics Data System (ADS)
Kim, Sang-Kyeom; Lee, Hyung-Suk; Park, Seok-Woo; Lee, Eun-Song; de Josselin de Jong, Elbert; Jung, Hoi-In; Kim, Baek-Il
2017-12-01
Various technologies used to objectively determine enamel thickness or dentin exposure have been suggested. However, most methods have clinical limitations. This study was conducted to confirm the potential of quantitative light-induced fluorescence (QLF) using autofluorescence intensity of occlusal surfaces of worn teeth according to enamel grinding depth in vitro. Sixteen permanent premolars were used. Each tooth was gradationally ground down at the occlusal surface in the apical direction. QLF-digital and swept-source optical coherence tomography images were acquired at each grinding depth (in steps of 100 μm). All QLF images were converted to 8-bit grayscale images to calculate the fluorescence intensity. The maximum brightness (MB) values of the same sound regions in grayscale images before (MB) and phased values after (MB) the grinding process were calculated. Finally, 13 samples were evaluated. MB increased over the grinding depth range with a strong correlation (r=0.994, P<0.001). In conclusion, the fluorescence intensity of the teeth and grinding depth was strongly correlated in the QLF images. Therefore, QLF technology may be a useful noninvasive tool used to monitor the progression of tooth wear and to conveniently estimate enamel thickness.
Color rendering indices in global illumination methods
NASA Astrophysics Data System (ADS)
Geisler-Moroder, David; Dür, Arne
2009-02-01
Human perception of material colors depends heavily on the nature of the light sources used for illumination. One and the same object can cause highly different color impressions when lit by a vapor lamp or by daylight, respectively. Based on state-of-the-art colorimetric methods we present a modern approach for calculating color rendering indices (CRI), which were defined by the International Commission on Illumination (CIE) to characterize color reproduction properties of illuminants. We update the standard CIE method in three main points: firstly, we use the CIELAB color space, secondly, we apply a Bradford transformation for chromatic adaptation, and finally, we evaluate color differences using the CIEDE2000 total color difference formula. Moreover, within a real-world scene, light incident on a measurement surface is composed of a direct and an indirect part. Neumann and Schanda1 have shown for the cube model that interreflections can influence the CRI of an illuminant. We analyze how color rendering indices vary in a real-world scene with mixed direct and indirect illumination and recommend the usage of a spectral rendering engine instead of an RGB based renderer for reasons of accuracy of CRI calculations.
Instantaneous phase-shifting Fizeau interferometry with high-speed pixelated phase-mask camera
NASA Astrophysics Data System (ADS)
Yatagai, Toyohiko; Jackin, Boaz Jessie; Ono, Akira; Kiyohara, Kosuke; Noguchi, Masato; Yoshii, Minoru; Kiyohara, Motosuke; Niwa, Hayato; Ikuo, Kazuyuki; Onuma, Takashi
2015-08-01
A Fizeou interferometer with instantaneous phase-shifting ability using a Wollaston prism is designed. to measure dynamic phase change of objects, a high-speed video camera of 10-5s of shutter speed is used with a pixelated phase-mask of 1024 × 1024 elements. The light source used is a laser of wavelength 532 nm which is split into orthogonal polarization states by passing through a Wollaston prism. By adjusting the tilt of the reference surface it is possible to make the reference and object beam with orthogonal polarizations states to coincide and interfere. Then the pixelated phase-mask camera calculate the phase changes and hence the optical path length difference. Vibration of speakers and turbulence of air flow were successfully measured in 7,000 frames/sec.
Cao, Lilly; McInnes, Matthew D F; Ryan, John O
2014-02-01
Little objective evidence exists regarding what makes a good lecture. Our purpose was to determine qualities of radiology review course lectures that are associated with positive audience evaluation. 57 presentations from the Ottawa Resident Review Course (2012) were analyzed by a PGY4 radiology resident blinded to the result of audience evaluation. Objective data extracted were: slides per minute, lines of text per text slide, words per text slide, cases per minute, images per minute, images per case, number of audience laughs, number of questions posed to the audience, number of summaries, inclusion of learning objectives, ending on time, use of pre/post-test and use of special effects. Mean audience evaluation scores for each talk from daily audience evaluations (up to 60 per talk) were standardized out of 100. Correlation coefficient was calculated between continuous variables and audience evaluation scores. Student T test was performed on categorical variables and audience evaluation scores. Strongest positive association with audience evaluation scores was for image quality (r = 0.57) and number of times the audience laughed (r = 0.3). Strongest negative association was between images per case and audience scores (r = -0.25). Talks with special effects were rated better (mean score 94.3 vs. 87.1, p < 0.001). Talks with the highest image quality were rated better (mean score 94.1 vs. 87.5, p < 0.001). Talks which contained a pre/post-test were rated better (mean score 92 vs. 87.8, p = 0.004). Many factors go into making a great review course lecture. At the University of Ottawa Resident Review Course, high quality images, use of special effects, use of pre/post-test and humor were most strongly associated with high audience evaluation scores. High image volume per case may be negatively associated with audience evaluation scores.
Pre-Service Teacher Training in Health and Well-Being in England: The State of the Nation
ERIC Educational Resources Information Center
Byrne, J.; Shepherd, J.; Dewhirst, S.; Pickett, K.; Speller, V.; Roderick, P.; Grace, M.; Almond, P.
2015-01-01
This paper presents findings from a survey of pre-service teacher training institutions in England with regard to the provision of health and well-being education. It examines factors affecting the inclusion of health and well-being, and explores educational implications in light of the changing landscape of pre-service teacher education in…
NASA Astrophysics Data System (ADS)
Bell, Cameron P. M.
2012-11-01
In this thesis a critical assessment of the ages derived using theoretical pre-main-sequence (pre-MS) stellar evolutionary models is presented by comparing the predictions to the low-mass pre-MS population of 14 young star-forming regions (SFRs) in colour-magnitude diagrams (CMDs). Deriving pre-MS ages requires precise distances and estimates of the reddening. Therefore, the main-sequence (MS) members of the SFRs have been used to derive a self-consistent set of statistically robust ages, distances and reddenings with associated uncertainties using a maximum-likelihood fitting statistic and MS evolutionary models. A photometric method for de-reddening individual stars - known as the Q-method - in regions where the extinction is spatially variable has been updated and is presented. The effects of both the model dependency and the SFR composition on these derived parameters are also discussed. The problem of calibrating photometric observations of red pre-MS stars is examined and it is shown that using observations of MS stars to transform the data into a standard photometric system can introduce significant errors in the position of the pre-MS locus in CMD space. Hence, it is crucial that precise photometric studies - especially of pre-MS objects - be carried out in the natural photometric system of the observations. This therefore requires a robust model of the system responses for the instrument used, and thus the calculated responses for the Wide-Field Camera on the Isaac Newton Telescope are presented. These system responses have been tested using standard star observations and have been shown to be a good representation of the photometric system. A benchmark test for the pre-MS evolutionary models is performed by comparing them to a set of well-calibrated CMDs of the Pleiades in the wavelength regime 0.4-2.5 μm. The masses predicted by these models are also tested against dynamical masses using a sample of MS binaries by calculating the system magnitude in a given photometric bandpass. This analysis shows that for Teff ≤ 4000 K the models systematically overestimate the flux by a factor of 2 at 0.5 μm, though this decreases with wavelength, becoming negligible at 2.2 μm. Thus before the pre-MS models are used to derive ages, a recalibration of the models is performed by incorporating an empirical colour-Teff relation and bolometric corrections based on the Ks-band luminosity of Pleiades members, with theoretical corrections for the dependence on the surface gravity (log g). The recalibrated pre-MS model isochrones are used to derive ages from the pre-MS populations of the SFRs. These ages are then compared with the MS derivations, thus providing a powerful diagnostic tool with which to discriminate between the different pre-MS age scales that arise from a much stronger model dependency in the pre-MS regime. The revised ages assigned to each of the 14 SFRs are up to a factor two older than previous derivations, a result with wide-ranging implications, including that circumstellar discs survive longer and that the average Class II lifetime is greater than currently believed.
Accuracy analysis for triangulation and tracking based on time-multiplexed structured light.
Wagner, Benjamin; Stüber, Patrick; Wissel, Tobias; Bruder, Ralf; Schweikard, Achim; Ernst, Floris
2014-08-01
The authors' research group is currently developing a new optical head tracking system for intracranial radiosurgery. This tracking system utilizes infrared laser light to measure features of the soft tissue on the patient's forehead. These features are intended to offer highly accurate registration with respect to the rigid skull structure by means of compensating for the soft tissue. In this context, the system also has to be able to quickly generate accurate reconstructions of the skin surface. For this purpose, the authors have developed a laser scanning device which uses time-multiplexed structured light to triangulate surface points. The accuracy of the authors' laser scanning device is analyzed and compared for different triangulation methods. These methods are given by the Linear-Eigen method and a nonlinear least squares method. Since Microsoft's Kinect camera represents an alternative for fast surface reconstruction, the authors' results are also compared to the triangulation accuracy of the Kinect device. Moreover, the authors' laser scanning device was used for tracking of a rigid object to determine how this process is influenced by the remaining triangulation errors. For this experiment, the scanning device was mounted to the end-effector of a robot to be able to calculate a ground truth for the tracking. The analysis of the triangulation accuracy of the authors' laser scanning device revealed a root mean square (RMS) error of 0.16 mm. In comparison, the analysis of the triangulation accuracy of the Kinect device revealed a RMS error of 0.89 mm. It turned out that the remaining triangulation errors only cause small inaccuracies for the tracking of a rigid object. Here, the tracking accuracy was given by a RMS translational error of 0.33 mm and a RMS rotational error of 0.12°. This paper shows that time-multiplexed structured light can be used to generate highly accurate reconstructions of surfaces. Furthermore, the reconstructed point sets can be used for high-accuracy tracking of objects, meeting the strict requirements of intracranial radiosurgery.
Astroinformatics in the Age of LSST: Analyzing the Summer 2012 Data Release
NASA Astrophysics Data System (ADS)
Borne, Kirk D.; De Lee, N. M.; Stassun, K.; Paegert, M.; Cargile, P.; Burger, D.; Bloom, J. S.; Richards, J.
2013-01-01
The Large Synoptic Survey Telescope (LSST) will image the visible southern sky every three nights. This multi-band, multi-epoch survey will produce a torrent of data, which traditional methods of object-by-object data analysis will not be able to accommodate. Thus the need for new astroinformatics tools to visualize, simulate, mine, and analyze this quantity of data. The Berkeley Center for Time-Domain Informatics (CTDI) is building the informatics infrastructure for generic light curve classification, including the innovation of new algorithms for feature generation and machine learning. The CTDI portal (http://dotastro.org) contains one of the largest collections of public light curves, with visualization and exploration tools. The group has also published the first calibrated probabilistic classification catalog of 50k variable stars along with a data exploration portal called http://bigmacc.info. Twice a year, the LSST collaboration releases simulated LSST data, in order to aid software development. This poster also showcases a suite of new tools from the Vanderbilt Initiative in Data-instensive Astrophysics (VIDA), designed to take advantage of these large data sets. VIDA's Filtergraph interactive web tool allows one to instantly create an interactive data portal for fast, real-time visualization of large data sets. Filtergraph enables quick selection of interesting objects by easily filtering on many different columns, 2-D and 3-D representations, and on-the-fly arithmetic calculations on the data. It also makes sharing the data and the tool with collaborators very easy. The EB/RRL Factory is a neural-network based variable star classifier, which is designed to quickly identify variable stars in a variety of classes from LSST light curve data (currently tuned to Eclipsing Binaries and RR Lyrae stars), and to provide likelihood-based orbital elements or stellar parameters as appropriate. Finally the LCsimulator software allows one to create simulated light curves of multiple types of variable stars based on an LSST cadence.
Exposure to dim light at night during early development increases adult anxiety-like responses.
Borniger, Jeremy C; McHenry, Zachary D; Abi Salloum, Bachir A; Nelson, Randy J
2014-06-22
Early experiences produce effects that may persist throughout life. Therefore, to understand adult phenotype, it is important to investigate the role of early environmental stimuli in adult behavior and health. Artificial light at night (LAN) is an increasingly common phenomenon throughout the world. However, animals, including humans, evolved under dark night conditions. Many studies have revealed affective, immune, and metabolic alterations provoked by aberrant light exposure and subsequent circadian disruption. Pups are receptive to entraining cues from the mother and then light early during development, raising the possibility that the early life light environment may influence subsequent behavior. Thus, to investigate potential influences of early life exposure to LAN on adult phenotype, we exposed mice to dim (~5 lux; full spectrum white light) or dark (~0 lux) nights pre- and/or postnatally. After weaning at 3 weeks of age, all mice were maintained in dark nights until adulthood (9 weeks of age) when behavior was assessed. Mice exposed to dim light in early life increased anxiety-like behavior and fearful responses on the elevated plus maze and passive avoidance tests. These mice also displayed reduced growth rates, which ultimately normalized during adolescence. mRNA expression of brain derived neurotrophic factor (BDNF), a neurotrophin previously linked to early life environment and adult phenotype, was not altered in the prefrontal cortex or hippocampus by early life LAN exposure. Serum corticosterone concentrations were similar between groups at weaning, suggesting that early life LAN does not elicit a long-term physiologic stress response. Dim light exposure did not influence behavior on the open field, novel object, sucrose anhedonia, or forced swim tests. Our data highlight the potential deleterious consequences of low levels of light during early life to development and subsequent behavior. Whether these changes are due to altered maternal behavior or persistent circadian abnormalities incurred by LAN remains to be determined. Copyright © 2014 Elsevier Inc. All rights reserved.
ERIC Educational Resources Information Center
Govender, I.; Grayson, D. J.
2008-01-01
This paper presents the results of an investigation into the various ways in which pre-service and in-service teachers experience learning to program in an object-oriented language. Both groups of teachers were enrolled in university courses. In most cases, the pre-service teachers were learning to program for the first time, while the in-service…
NASA Astrophysics Data System (ADS)
Sajjadi, Seyed; Buelna, Xavier; Eloranta, Jussi
2018-01-01
Application of inexpensive light emitting diodes as backlight sources for time-resolved shadowgraph imaging is demonstrated. The two light sources tested are able to produce light pulse sequences in the nanosecond and microsecond time regimes. After determining their time response characteristics, the diodes were applied to study the gas bubble formation around laser-heated copper nanoparticles in superfluid helium at 1.7 K and to determine the local cavitation bubble dynamics around fast moving metal micro-particles in the liquid. A convolutional neural network algorithm for analyzing the shadowgraph images by a computer is presented and the method is validated against the results from manual image analysis. The second application employed the red-green-blue light emitting diode source that produces light pulse sequences of the individual colors such that three separate shadowgraph frames can be recorded onto the color pixels of a charge-coupled device camera. Such an image sequence can be used to determine the moving object geometry, local velocity, and acceleration/deceleration. These data can be used to calculate, for example, the instantaneous Reynolds number for the liquid flow around the particle. Although specifically demonstrated for superfluid helium, the technique can be used to study the dynamic response of any medium that exhibits spatial variations in the index of refraction.
Automatic diagnostic system for measuring ocular refractive errors
NASA Astrophysics Data System (ADS)
Ventura, Liliane; Chiaradia, Caio; de Sousa, Sidney J. F.; de Castro, Jarbas C.
1996-05-01
Ocular refractive errors (myopia, hyperopia and astigmatism) are automatic and objectively determined by projecting a light target onto the retina using an infra-red (850 nm) diode laser. The light vergence which emerges from the eye (light scattered from the retina) is evaluated in order to determine the corresponding ametropia. The system basically consists of projecting a target (ring) onto the retina and analyzing the scattered light with a CCD camera. The light scattered by the eye is divided into six portions (3 meridians) by using a mask and a set of six prisms. The distance between the two images provided by each of the meridians, leads to the refractive error of the referred meridian. Hence, it is possible to determine the refractive error at three different meridians, which gives the exact solution for the eye's refractive error (spherical and cylindrical components and the axis of the astigmatism). The computational basis used for the image analysis is a heuristic search, which provides satisfactory calculation times for our purposes. The peculiar shape of the target, a ring, provides a wider range of measurement and also saves parts of the retina from unnecessary laser irradiation. Measurements were done in artificial and in vivo eyes (using cicloplegics) and the results were in good agreement with the retinoscopic measurements.
Polarized light scattering as a probe for changes in chromosome structure
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shapiro, Daniel Benjamin
1993-10-01
Measurements and calculations of polarized light scattering are applied to chromosomes. Calculations of the Mueller matrix, which completely describes how the polarization state of light is altered upon scattering, are developed for helical structures related to that of chromosomes. Measurements of the Mueller matrix are presented for octopus sperm heads, and dinoflagellates. Comparisons of theory and experiment are made. A working theory of polarized light scattering from helices is developed. The use of the first Born approximation vs the coupled dipole approximation are investigated. A comparison of continuous, calculated in this work, and discrete models is also discussed. By comparingmore » light scattering measurements with theoretical predictions the average orientation of DNA in an octopus sperm head is determined. Calculations are made for the Mueller matrix of DNA plectonemic helices at UV, visible and X-ray wavelengths. Finally evidence is presented that the chromosomes of dinoflagellates are responsible for observed differential scattering of circularly-polarized light. This differential scattering is found to vary in a manner that is possibly correlated to the cell cycle of the dinoflagellates. It is concluded that by properly choosing the wavelength probe polarized light scattering can provide a useful tool to study chromosome structure.« less
3D Imaging with Holographic Tomography
NASA Astrophysics Data System (ADS)
Sheppard, Colin J. R.; Kou, Shan Shan
2010-04-01
There are two main types of tomography that enable the 3D internal structures of objects to be reconstructed from scattered data. The commonly known computerized tomography (CT) give good results in the x-ray wavelength range where the filtered back-projection theorem and Radon transform can be used. These techniques rely on the Fourier projection-slice theorem where rays are considered to propagate straight through the object. Another type of tomography called `diffraction tomography' applies in applications in optics and acoustics where diffraction and scattering effects must be taken into account. The latter proves to be a more difficult problem, as light no longer travels straight through the sample. Holographic tomography is a popular way of performing diffraction tomography and there has been active experimental research on reconstructing complex refractive index data using this approach recently. However, there are two distinct ways of doing tomography: either by rotation of the object or by rotation of the illumination while fixing the detector. The difference between these two setups is intuitive but needs to be quantified. From Fourier optics and information transformation point of view, we use 3D transfer function analysis to quantitatively describe how spatial frequencies of the object are mapped to the Fourier domain. We first employ a paraxial treatment by calculating the Fourier transform of the defocused OTF. The shape of the calculated 3D CTF for tomography, by scanning the illumination in one direction only, takes on a form that we might call a 'peanut,' compared to the case of object rotation, where a diablo is formed, the peanut exhibiting significant differences and non-isotropy. In particular, there is a line singularity along one transverse direction. Under high numerical aperture conditions, the paraxial treatment is not accurate, and so we make use of 3D analytical geometry to calculate the behaviour in the non-paraxial case. This time, we obtain a similar peanut, but without the line singularity.
Axial-Current Matrix Elements in Light Nuclei from Lattice QCD
NASA Astrophysics Data System (ADS)
Savage, M.; Beane, S.; Chang, E.; Davoudi, Z.; Detmold, W.; Orginos, K.; Shanahan, P.; Tiburzi, B.; Wagman, M.; Winter, F.; Nplqcd Collaboration
I present results from the first lattice QCD calculations of axial-current matrix elements in light nuclei, performed by the NPLQCD collaboration. Precision calculations of these matrix elements, and the subsequent extraction of multi-nucleon axial-current operators, are essential in refining theoretical predictions of the proton-proton fusion cross section, neutrino-nucleus cross sections and $\\beta\\beta$-decay rates of nuclei. In addition, they are expected to shed light on the phenomenological quenching of $g_A$ that is required in nuclear many-body calculations.
Light absorption and excitation energy transfer calculations in primitive photosynthetic bacteria
NASA Astrophysics Data System (ADS)
Komatsu, Yu; Kayanuma, Megumi; Shoji, Mitsuo; Yabana, Kazuhiro; Shiraishi, Kenji; Umemura, Masayuki
2015-06-01
In photosynthetic organisms, light energy is converted into chemical energy through the light absorption and excitation energy transfer (EET) processes. These processes start in light-harvesting complexes, which contain special photosynthetic pigments. The exploration of unique mechanisms in light-harvesting complexes is directly related to studies, such as artificial photosynthesis or biosignatures in astrobiology. We examined, through ab initio calculations, the light absorption and EET processes using cluster models of light-harvesting complexes in purple bacteria (LH2). We evaluated absorption spectra and energy transfer rates using the LH2 monomer and dimer models to reproduce experimental results. After the calibration tests, a LH2 aggregation model, composed of 7 or 19 LH2s aligned in triangle lattice, was examined. We found that the light absorption is red shifted and the energy transfer becomes faster as the system size increases. We also found that EET is accelerated by exchanging the central pigments to lower energy excited pigments. As an astrobiological application, we calculated light absorptions efficiencies of the LH2 in different photoenvironments.
Four queries concerning the metaphysics of early human embryogenesis.
Howsepian, A A
2008-04-01
In this essay, I attempt to provide answers to the following four queries concerning the metaphysics of early human embryogenesis. (1) Following its first cellular fission, is it coherent to claim that one and only one of two "blastomeric" twins of a human zygote is identical with that zygote? (2) Following the fusion of two human pre-embryos, is it coherent to claim that one and only one pre-fusion pre-embryo is identical with that postfusion pre-embryo? (3) Does a live human being come into existence only when its brain comes into existence? (4) At implantation, does a pre-embryo become a mere part of its mother? I argue that either if things have quidditative properties or if criterialism is false, then queries (1) and (2) can be answered in the affirmative; that in light of recent developments in theories of human death and in light of a more "functional" theory of brains, query (3) can be answered in the negative; and that plausible mereological principles require a negative answer to query (4).
Finch, Anthony J; Benson, Jamie M; Donnelly, Patrick E; Torzilli, Peter A
2017-06-01
Objective Many in vivo procedures to repair chondral defects use ultraviolet (UV)-photoinitiated in situ polymerization within the cartilage matrix. Chemical species that absorb UV light might reduce the effectiveness of these procedures by acting as light absorption barriers. This study evaluated whether any of the individual native biochemical components in cartilage and synovial fluid interfered with the absorption of light by common scaffolding photosensitizers. Materials UV-visible spectroscopy was performed on each major component of cartilage in solution, on bovine synovial fluid, and on four photosensitizers, riboflavin, Irgacure 2959, quinine, and riboflavin-5'-phosphate. Molar extinction and absorption coefficients were calculated at wavelengths of maximum absorbance and 365 nm. Intact articular cartilage was also examined. Results The individual major biochemical components of cartilage, Irgacure 2959, and quinine did not exhibit a significant absorption at 365 nm. Riboflavin and riboflavin-5'-phosphate were more effectual light absorbers at 365 nm, compared with the individual native species. Intact cartilage absorbed a significantly greater amount of UV light in comparison with the native species. Conclusion Our results indicate that none of the individual native species in cartilage will interfere with the absorption of UV light at 365 nm by these commonly used photoinitiators. Intact cartilage slices exhibited significant light absorption at 365 nm, while also having distinct absorbance peaks at wavelengths less than 300 nm. Determining the UV absorptive properties of the biomolecules native to articular cartilage and synovial fluid will aid in optimizing scaffolding procedures to ensure sufficient scaffold polymerization at a minimum UV intensity.
Scanning optical microscope with long working distance objective
Cloutier, Sylvain G.
2010-10-19
A scanning optical microscope, including: a light source to generate a beam of probe light; collimation optics to substantially collimate the probe beam; a probe-result beamsplitter; a long working-distance, infinity-corrected objective; scanning means to scan a beam spot of the focused probe beam on or within a sample; relay optics; and a detector. The collimation optics are disposed in the probe beam. The probe-result beamsplitter is arranged in the optical paths of the probe beam and the resultant light from the sample. The beamsplitter reflects the probe beam into the objective and transmits resultant light. The long working-distance, infinity-corrected objective is also arranged in the optical paths of the probe beam and the resultant light. It focuses the reflected probe beam onto the sample, and collects and substantially collimates the resultant light. The relay optics are arranged to relay the transmitted resultant light from the beamsplitter to the detector.
Wu, Haining; Dong, Jianfei; Qi, Gaojin; Zhang, Guoqi
2015-07-01
Enhancing the colorfulness of illuminated objects is a promising application of LED lighting for commercial, exhibiting, and scientific purposes. This paper proposes a method to enhance the color of illuminated objects for a given polychromatic lamp. Meanwhile, the light color is restricted to white. We further relax the white light constraints by introducing soft margins. Based on the spectral and electrical characteristics of LEDs and object surface properties, we determine the optimal mixing of the LED light spectrum by solving a numerical optimization problem, which is a quadratic fractional programming problem by formulation. Simulation studies show that the trade-off between the white light constraint and the level of the color enhancement can be adjusted by tuning an upper limit value of the soft margin. Furthermore, visual evaluation experiments are performed to evaluate human perception of the color enhancement. The experiments have verified the effectiveness of the proposed method.
Object Detection and Classification by Decision-Level Fusion for Intelligent Vehicle Systems.
Oh, Sang-Il; Kang, Hang-Bong
2017-01-22
To understand driving environments effectively, it is important to achieve accurate detection and classification of objects detected by sensor-based intelligent vehicle systems, which are significantly important tasks. Object detection is performed for the localization of objects, whereas object classification recognizes object classes from detected object regions. For accurate object detection and classification, fusing multiple sensor information into a key component of the representation and perception processes is necessary. In this paper, we propose a new object-detection and classification method using decision-level fusion. We fuse the classification outputs from independent unary classifiers, such as 3D point clouds and image data using a convolutional neural network (CNN). The unary classifiers for the two sensors are the CNN with five layers, which use more than two pre-trained convolutional layers to consider local to global features as data representation. To represent data using convolutional layers, we apply region of interest (ROI) pooling to the outputs of each layer on the object candidate regions generated using object proposal generation to realize color flattening and semantic grouping for charge-coupled device and Light Detection And Ranging (LiDAR) sensors. We evaluate our proposed method on a KITTI benchmark dataset to detect and classify three object classes: cars, pedestrians and cyclists. The evaluation results show that the proposed method achieves better performance than the previous methods. Our proposed method extracted approximately 500 proposals on a 1226 × 370 image, whereas the original selective search method extracted approximately 10 6 × n proposals. We obtained classification performance with 77.72% mean average precision over the entirety of the classes in the moderate detection level of the KITTI benchmark dataset.
Object Detection and Classification by Decision-Level Fusion for Intelligent Vehicle Systems
Oh, Sang-Il; Kang, Hang-Bong
2017-01-01
To understand driving environments effectively, it is important to achieve accurate detection and classification of objects detected by sensor-based intelligent vehicle systems, which are significantly important tasks. Object detection is performed for the localization of objects, whereas object classification recognizes object classes from detected object regions. For accurate object detection and classification, fusing multiple sensor information into a key component of the representation and perception processes is necessary. In this paper, we propose a new object-detection and classification method using decision-level fusion. We fuse the classification outputs from independent unary classifiers, such as 3D point clouds and image data using a convolutional neural network (CNN). The unary classifiers for the two sensors are the CNN with five layers, which use more than two pre-trained convolutional layers to consider local to global features as data representation. To represent data using convolutional layers, we apply region of interest (ROI) pooling to the outputs of each layer on the object candidate regions generated using object proposal generation to realize color flattening and semantic grouping for charge-coupled device and Light Detection And Ranging (LiDAR) sensors. We evaluate our proposed method on a KITTI benchmark dataset to detect and classify three object classes: cars, pedestrians and cyclists. The evaluation results show that the proposed method achieves better performance than the previous methods. Our proposed method extracted approximately 500 proposals on a 1226×370 image, whereas the original selective search method extracted approximately 106×n proposals. We obtained classification performance with 77.72% mean average precision over the entirety of the classes in the moderate detection level of the KITTI benchmark dataset. PMID:28117742
Transmission electron microscopy as a tool for nanocrystal characterization pre- and post-injector
Stevenson, H. P.; DePonte, D. P.; Makhov, A. M.; Conway, James F.; Zeldin, O. B.; Boutet, S.; Calero, G.; Cohen, A. E.
2014-01-01
Recent advancements at the Linac Coherent Light Source X-ray free-electron laser (XFEL) enabling successful serial femtosecond diffraction experiments using nanometre-sized crystals (NCs) have opened up the possibility of X-ray structure determination of proteins that produce only submicrometre crystals such as many membrane proteins. Careful crystal pre-characterization including compatibility testing of the sample delivery method is essential to ensure efficient use of the limited beamtime available at XFEL sources. This work demonstrates the utility of transmission electron microscopy for detecting and evaluating NCs within the carrier solutions of liquid injectors. The diffraction quality of these crystals may be assessed by examining the crystal lattice and by calculating the fast Fourier transform of the image. Injector reservoir solutions, as well as solutions collected post-injection, were evaluated for three types of protein NCs (i) the membrane protein PTHR1, (ii) the multi-protein complex Pol II-GFP and (iii) the soluble protein lysozyme. Our results indicate that the concentration and diffraction quality of NCs, particularly those with high solvent content and sensitivity to mechanical manipulation may be affected by the delivery process. PMID:24914151
Effects of circadian disruption on methamphetamine consumption in methamphetamine-exposed rats.
Doyle, Susan E; Feng, Hanting; Garber, Garrett; Menaker, Michael; Lynch, Wendy J
2015-06-01
A substantial number of clinical studies indicate associations between sleep abnormalities and drug abuse; however, the role played by the circadian system in the development of addiction is largely unknown. The aim of this study was to examine the effects of experimentally induced chronic jet lag on methamphetamine consumption in a rat model of methamphetamine drinking. Male Sprague-Dawley rats (n = 32) were housed in running wheel cages in a 12:12 h light:dark cycle. One group of rats (n = 16) was given 2 weeks of forced methamphetamine consumption (0.01 % in drinking water; meth pre-exposed) while a second group (n = 16, not pre-exposed) received water only. This was followed by a 2-week abstinence period during which half of the animals from each group were exposed to four consecutive 6-h advancing phase shifts of the light:dark cycle, while the other half remained on the original light:dark cycle. Methamphetamine consumption was assessed in all rats following the deprivation period using a two-bottle choice paradigm. Methamphetamine consumption was initially lower in methamphetamine pre-exposed versus not pre-exposed rats. However, during the second week following abstinence, consumption was significantly higher in phase-shifted rats of the methamphetamine pre-exposed group compared to all other groups. These data reveal an effect of circadian rhythm disturbance on methamphetamine consumption and suggest that dysregulation of the circadian system be considered in the etiology of relapse and addiction.
NASA Astrophysics Data System (ADS)
Cui, Y.; Liu, Y.; Peng, L.; Qin, Y.
2017-12-01
Arsenic was a typical toxic metalloid element and its contamination in groundwater was widely recognized as a global health problem, especially in north China, where people depended on groundwater as water resource. Arsenic was existed as As(III) in underground water, and has low affinity to the surface of various minerals and more toxic and more difficultly to be removed compared with As(V), so a pre-oxidation technology by transforming As (III) to As (V) is highly desirable. Electrochemical and oxidizing agents were traditional technology, which usually causes secondary pollution. A novel methodology is presented here, using prepared magnetic visible-light-driven nanomaterials as recyclable media to investigate As(III) pre-oxidation processing. Ag@AgCl core-shell nanowires were first synthesized by oxidation of Ag nanowires with moderate FeCl3, and exhibited excellent photocatalytic activity to As(III) with visible-light. The ratio of chloridization was proved to act as key effect on photocatalytic oxidation efficiency. Testing with simulated groundwater condition proved that pH, ionic strength and concentration of humic acid have obvious effects on Ag@AgCl photocatalytic ability. h+ and ·O2- were confirmed to be the main active species during the visible-light driven photocatalytic oxidation process for As(III) by trapping experiments with radical scavengers. Then Fe0 was introduced to prepare Fe-Ag nanowire and chloridized into Fe-Ag@AgCl to provide magnetic characteristic. The magnetic recycling and re-chloride experiments validated this visible-light-driven material has excellent stable and high reused ability as photocatalyst under visible light irradiation.
Optical inspection system for cylindrical objects
Brenden, Byron B.; Peters, Timothy J.
1989-01-01
In the inspection of cylindrical objects, particularly O-rings, the object is translated through a field of view and a linear light trace is projected on its surface. An image of the light trace is projected on a mask, which has a size and shape corresponding to the size and shape which the image would have if the surface of the object were perfect. If there is a defect, light will pass the mask and be sensed by a detector positioned behind the mask. Preferably, two masks and associated detectors are used, one mask being convex to pass light when the light trace falls on a projection from the surface and the other concave, to pass light when the light trace falls on a depression in the surface. The light trace may be either dynamic, formed by a scanned laser beam, or static, formed by such a beam focussed by a cylindrical lens. Means are provided to automatically keep the illuminating receiving systems properly aligned.
Brodin, N. Patrik; Guha, Chandan; Tomé, Wolfgang A.
2015-01-01
Modern pre-clinical radiation therapy (RT) research requires high precision and accurate dosimetry to facilitate the translation of research findings into clinical practice. Several systems are available that provide precise delivery and on-board imaging capabilities, highlighting the need for a quality management program (QMP) to ensure consistent and accurate radiation dose delivery. An ongoing, simple, and efficient QMP for image-guided robotic small animal irradiators used in pre-clinical RT research is described. Protocols were developed and implemented to assess the dose output constancy (based on the AAPM TG-61 protocol), cone-beam computed tomography (CBCT) image quality and object representation accuracy (using a custom-designed imaging phantom), CBCT-guided target localization accuracy and consistency of the CBCT-based dose calculation. To facilitate an efficient read-out and limit the user dependence of the QMP data analysis, a semi-automatic image analysis and data representation program was developed using the technical computing software MATLAB. The results of the first six months experience using the suggested QMP for a Small Animal Radiation Research Platform (SARRP) are presented, with data collected on a bi-monthly basis. The dosimetric output constancy was established to be within ±1 %, the consistency of the image resolution was within ±0.2 mm, the accuracy of CBCT-guided target localization was within ±0.5 mm, and dose calculation consistency was within ±2 s (± 3 %) per treatment beam. Based on these results, this simple quality assurance program allows for the detection of inconsistencies in dosimetric or imaging parameters that are beyond the acceptable variability for a reliable and accurate pre-clinical RT system, on a monthly or bi-monthly basis. PMID:26425981
Brodin, N Patrik; Guha, Chandan; Tomé, Wolfgang A
2015-11-01
Modern pre-clinical radiation therapy (RT) research requires high precision and accurate dosimetry to facilitate the translation of research findings into clinical practice. Several systems are available that provide precise delivery and on-board imaging capabilities, highlighting the need for a quality management program (QMP) to ensure consistent and accurate radiation dose delivery. An ongoing, simple, and efficient QMP for image-guided robotic small animal irradiators used in pre-clinical RT research is described. Protocols were developed and implemented to assess the dose output constancy (based on the AAPM TG-61 protocol), cone-beam computed tomography (CBCT) image quality and object representation accuracy (using a custom-designed imaging phantom), CBCT-guided target localization accuracy and consistency of the CBCT-based dose calculation. To facilitate an efficient read-out and limit the user dependence of the QMP data analysis, a semi-automatic image analysis and data representation program was developed using the technical computing software MATLAB. The results of the first 6-mo experience using the suggested QMP for a Small Animal Radiation Research Platform (SARRP) are presented, with data collected on a bi-monthly basis. The dosimetric output constancy was established to be within ±1 %, the consistency of the image resolution was within ±0.2 mm, the accuracy of CBCT-guided target localization was within ±0.5 mm, and dose calculation consistency was within ±2 s (±3%) per treatment beam. Based on these results, this simple quality assurance program allows for the detection of inconsistencies in dosimetric or imaging parameters that are beyond the acceptable variability for a reliable and accurate pre-clinical RT system, on a monthly or bi-monthly basis.
Parental education and physical activity in pre-school children.
Vale, S; Ricardo, N; Soares-Miranda, L; Santos, R; Moreira, C; Mota, J
2014-05-01
The purpose of this study was to objectively assess pre-school children's total physical activity (TPA) patterns and compliance with guidelines and to examine differences relative to parental education. The sample consisted on 509 healthy pre-school children, aged 3-6 years recruited from kindergartens located in the metropolitan area of Porto, Portugal. The PA was assessed for 7 consecutive days by accelerometry. For TPA, we followed the guidelines of the National Association for Sport and Physical Education (NASPE) (children who spent at least >120 min per day in active play). For TPA, we calculated the proportion of children who spent at least >120 min per day in active play and moderate-to-vigorous physical activity (MVPA), we calculated the proportion of children who spent at least >60 min per day in active play. Parental education was analysed according to the Portuguese education system. Children with parents in the highest education level were less active than children from low and middle education level (P ≤ 0.001) in all patterns of PA (week and weekend). Regarding TPA during the week we found that the majority of children from low and middle parental education meet the NASPE guidelines. On the other hand, more than half the children from high parental education did not meet these recommendations (P ≤ 0.001) and MVPA recommendations (P ≤ 0.05). In both recommendations, children from low parental education were twice more likely to meet the recommendations compared with children belonging to high parental education. Parent education was negatively associated with children's daily physical activity patterns and compliance with guidelines. © 2013 John Wiley & Sons Ltd.
Poitras, Julien; Chauny, Jean-Marc; Lévesque, Jean-Frédéric; Ouimet, Mathieu; Dupuis, Gilles; Tanguay, Alain; Simard-Racine, Geneviève
2015-01-01
Introduction Health services research generates useful knowledge. Promotion of implementation of this knowledge in medical practice is essential. Prior to initiation of a major study on rural emergency departments (EDs), we deployed two knowledge transfer strategies designed to generate interest and engagement from potential knowledge users. The objective of this paper was to review: 1) a combined project launch and media press release strategy, and 2) a pre-study survey designed to survey potential knowledge users’ opinions on the proposed study variables. Materials and Methods We evaluated the impact of the project launch (presentation at two conferences hosted by key stakeholders) and media press release via a survey of participants/stakeholders and by calculating the number of media interview requests and reports generated. We used a pre-study survey to collect potential key stakeholder’ opinions on the study variables. Results Twenty-one of Quebec’s 26 rural EDs participated in the pre-study survey (81% participation rate). The press release about the study generated 51 press articles and 20 media request for interviews, and contributed to public awareness of a major rural research initiative. In the pre-study survey, thirteen participants (46%) mentioned prior knowledge of the research project. Results from the pre-study survey revealed that all of the potential study variables were considered to be relevant for inclusion in the research project. Respondents also proposed additional variables of interest, including factors promoting retention of human resources. Conclusions The present study demonstrated the potential utility of a two-pronged knowledge transfer strategy, including a combined formal launch and press release, and a pre-study survey designed to ensure that the included variables were of interest to participants and stakeholders. PMID:25849328
Van Capelle, Abbey; Broderick, Carolyn R; van Doorn, Nancy; E Ward, Rachel; Parmenter, Belinda J
2017-07-01
Mastery in -fundamental motor skills (FMS) is associated with increased physical activity (PA) in school-aged children; however, there is limited research on pre-schoolers (3-5 years). We aimed to evaluate interventions for improving FMS as well as PA. A search of electronic databases was conducted for controlled trials using PA interventions with FMS as outcomes in healthy pre-schoolers. Standardised mean difference (SMD), 95% confidence intervals and publication bias were calculated for each outcome using Revman 5.3. Twenty trials met inclusion criteria. In total, 4255 pre-schoolers were analysed with 854 completing a FMS intervention. Studies were categorised into three groups (i) Teacher-Led (TL)(n=13); (ii) Child-Centred (CC)(n=6) and (iii) Parent-Led (PL)(n=1). Mean age was 4.3±0.4 years, with equal gender distribution. Interventions ran for 21±17 weeks, 3±1 times per week for 35±17 minutes. TL interventions significantly improved overall FMS (SMD=0.14[0.06, 0.21]; p=0.0003), object control (SMD=0.47[0.15, 0.80]; p= 0.004), and locomotor skills (SMD=0.44[0.16, 0.73]; p=0.002), whereas CC interventions were not significant. There was a small, non-significant reduction in sedentary time (SMD=-0.35[-0.80, 0.10]; p= 0.12), and a large non-significant increase in PA (SMD=0.79[-0.83, 2.41]; p=0.34). PA interventions improve FMS in pre-schoolers; however, due to limited research, more study is needed on CC interventions. Targeting FMS development in pre-schoolers may promote higher PA levels and reduce sedentary time, however more study is needed. Copyright © 2017 Sports Medicine Australia. All rights reserved.
Delirium prediction in the intensive care unit: comparison of two delirium prediction models.
Wassenaar, Annelies; Schoonhoven, Lisette; Devlin, John W; van Haren, Frank M P; Slooter, Arjen J C; Jorens, Philippe G; van der Jagt, Mathieu; Simons, Koen S; Egerod, Ingrid; Burry, Lisa D; Beishuizen, Albertus; Matos, Joaquim; Donders, A Rogier T; Pickkers, Peter; van den Boogaard, Mark
2018-05-05
Accurate prediction of delirium in the intensive care unit (ICU) may facilitate efficient use of early preventive strategies and stratification of ICU patients by delirium risk in clinical research, but the optimal delirium prediction model to use is unclear. We compared the predictive performance and user convenience of the prediction model for delirium (PRE-DELIRIC) and early prediction model for delirium (E-PRE-DELIRIC) in ICU patients and determined the value of a two-stage calculation. This 7-country, 11-hospital, prospective cohort study evaluated consecutive adults admitted to the ICU who could be reliably assessed for delirium using the Confusion Assessment Method-ICU or the Intensive Care Delirium Screening Checklist. The predictive performance of the models was measured using the area under the receiver operating characteristic curve. Calibration was assessed graphically. A physician questionnaire evaluated user convenience. For the two-stage calculation we used E-PRE-DELIRIC immediately after ICU admission and updated the prediction using PRE-DELIRIC after 24 h. In total 2178 patients were included. The area under the receiver operating characteristic curve was significantly greater for PRE-DELIRIC (0.74 (95% confidence interval 0.71-0.76)) compared to E-PRE-DELIRIC (0.68 (95% confidence interval 0.66-0.71)) (z score of - 2.73 (p < 0.01)). Both models were well-calibrated. The sensitivity improved when using the two-stage calculation in low-risk patients. Compared to PRE-DELIRIC, ICU physicians (n = 68) rated the E-PRE-DELIRIC model more feasible. While both ICU delirium prediction models have moderate-to-good performance, the PRE-DELIRIC model predicts delirium better. However, ICU physicians rated the user convenience of E-PRE-DELIRIC superior to PRE-DELIRIC. In low-risk patients the delirium prediction further improves after an update with the PRE-DELIRIC model after 24 h. ClinicalTrials.gov, NCT02518646 . Registered on 21 July 2015.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-06
... Light & Power Company; Notice of Intent To File License Application, Filing of Pre-Application Document.... Date Filed: March 29, 2013. d. Submitted By: Alaska Electric Light & Power Company (AEL&P). e. Name of... Act and the joint agency regulations thereunder at 50 CFR, Part 402; (b) NOAA Fisheries under section...
Gallazzi, Enrico; Drago, Lorenzo; Baldini, Andrea; Stockley, Ian; George, David A; Scarponi, Sara; Romanò, Carlo L
2017-01-01
Background : Differentiating between septic and aseptic joint prosthesis may be challenging, since no single test is able to confirm or rule out infection. The choice and interpretation of the panel of tests performed in any case often relies on empirical evaluation and poorly validated scores. The "Combined Diagnostic Tool (CDT)" App, a smartphone application for iOS, was developed to allow to automatically calculate the probability of having a of periprosthetic joint infection, on the basis of the relative sensitivity and specificity of the positive and negative diagnostic tests performed in any given patient. Objective : The aim of the present study was to apply the CDT software to investigate the ability of the tests routinely performed in three high-volume European centers to diagnose a periprosthetic infection. Methods : This three-center retrospective study included 120 consecutive patients undergoing total hip or knee revision, and included 65 infected patients (Group A) and 55 patients without infection (Group B). The following parameters were evaluated: number and type of positive and negative diagnostic tests performed pre-, intra- and post-operatively and resultant probability calculated by the CDT App of having a peri-prosthetic joint infection, based on pre-, intra- and post-operative combined tests. Results : Serological tests were the most common performed, with an average 2.7 tests per patient for Group A and 2.2 for Group B, followed by joint aspiration (0.9 and 0.8 tests per patient, respectively) and imaging techniques (0.5 and 0.2 test per patient). Mean CDT App calculated probability of having an infection based on pre-operative tests was 79.4% for patients in Group A and 35.7 in Group B. Twenty-nine patients in Group A had > 10% chance of not having an infection, and 29 of Group B had > 10% chance of having an infection. Conclusion : This is the first retrospective study focused on investigating the number and type of tests commonly performed prior to joint revision surgery and aimed at evaluating their combined ability to diagnose a peri-prosthetic infection. CDT App allowed us to demonstrate that, on average, the routine combination of commonly used tests is unable to diagnose pre-operatively a peri-prosthetic infection with a probability higher than 90%.
A Novel Testing Model for Opportunistic Screening of Pre-Diabetes and Diabetes among U.S. Adults
Zhang, Yurong; Hu, Gang; Zhang, Lu; Mayo, Rachel; Chen, Liwei
2015-01-01
Objective The study aim was to evaluate the performance of a novel simultaneous testing model, based on the Finnish Diabetes Risk Score (FINDRISC) and HbA1c, in detecting undiagnosed diabetes and pre-diabetes in Americans. Research Design and Methods This cross-sectional analysis included 3,886 men and women (≥ 20 years) without known diabetes from the U.S. National Health and Nutrition Examination Survey (NHANES) 2005-2010. The FINDRISC was developed based on eight variables (age, BMI, waist circumference, use of antihypertensive drug, history of high blood glucose, family history of diabetes, daily physical activity and fruit & vegetable intake). The sensitivity, specificity, and the receiver operating characteristic (ROC) curve of the testing model were calculated for undiagnosed diabetes and pre-diabetes, determined by oral glucose tolerance test (OGTT). Results The prevalence of undiagnosed diabetes was 7.0% and 43.1% for pre-diabetes (27.7% for isolated impaired fasting glucose (IFG), 5.1% for impaired glucose tolerance (IGT), and 10.3% for having both IFG and IGT). The sensitivity and specificity of using the HbA1c alone was 24.2% and 99.6% for diabetes (cutoff of ≥6.5%), and 35.2% and 86.4% for pre-diabetes (cutoff of ≥5.7%). The sensitivity and specificity of using the FINDRISC alone (cutoff of ≥9) was 79.1% and 48.6% for diabetes and 60.2% and 61.4% for pre-diabetes. Using the simultaneous testing model with a combination of FINDRISC and HbA1c improved the sensitivity to 84.2% for diabetes and 74.2% for pre-diabetes. The specificity for the simultaneous testing model was 48.4% of diabetes and 53.0% for pre-diabetes. Conclusions This simultaneous testing model is a practical and valid tool in diabetes screening in the general U.S. population. PMID:25790106
Depth perception camera for autonomous vehicle applications
NASA Astrophysics Data System (ADS)
Kornreich, Philipp
2013-05-01
An imager that can measure the distance from each pixel to the point on the object that is in focus at the pixel is described. Since it provides numeric information of the distance from the camera to all points in its field of view it is ideally suited for autonomous vehicle navigation and robotic vision. This eliminates the LIDAR conventionally used for range measurements. The light arriving at a pixel through a convex lens adds constructively only if it comes from the object point in focus at this pixel. The light from all other object points cancels. Thus, the lens selects the point on the object who's range is to be determined. The range measurement is accomplished by short light guides at each pixel. The light guides contain a p - n junction and a pair of contacts along its length. They, too, contain light sensing elements along the length. The device uses ambient light that is only coherent in spherical shell shaped light packets of thickness of one coherence length. Each of the frequency components of the broad band light arriving at a pixel has a phase proportional to the distance from an object point to its image pixel.
Integration of a high-NA light microscope in a scanning electron microscope.
Zonnevylle, A C; Van Tol, R F C; Liv, N; Narvaez, A C; Effting, A P J; Kruit, P; Hoogenboom, J P
2013-10-01
We present an integrated light-electron microscope in which an inverted high-NA objective lens is positioned inside a scanning electron microscope (SEM). The SEM objective lens and the light objective lens have a common axis and focal plane, allowing high-resolution optical microscopy and scanning electron microscopy on the same area of a sample simultaneously. Components for light illumination and detection can be mounted outside the vacuum, enabling flexibility in the construction of the light microscope. The light objective lens can be positioned underneath the SEM objective lens during operation for sub-10 μm alignment of the fields of view of the light and electron microscopes. We demonstrate in situ epifluorescence microscopy in the SEM with a numerical aperture of 1.4 using vacuum-compatible immersion oil. For a 40-nm-diameter fluorescent polymer nanoparticle, an intensity profile with a FWHM of 380 nm is measured whereas the SEM performance is uncompromised. The integrated instrument may offer new possibilities for correlative light and electron microscopy in the life sciences as well as in physics and chemistry. © 2013 The Authors Journal of Microscopy © 2013 Royal Microscopical Society.
Automatic Lamp and Fan Control Based on Microcontroller
NASA Astrophysics Data System (ADS)
Widyaningrum, V. T.; Pramudita, Y. D.
2018-01-01
In general, automation can be described as a process following pre-determined sequential steps with a little or without any human exertion. Automation is provided with the use of various sensors suitable to observe the production processes, actuators and different techniques and devices. In this research, the automation system developed is an automatic lamp and an automatic fan on the smart home. Both of these systems will be processed using an Arduino Mega 2560 microcontroller. A microcontroller is used to obtain values of physical conditions through sensors connected to it. In the automatic lamp system required sensors to detect the light of the LDR (Light Dependent Resistor) sensor. While the automatic fan system required sensors to detect the temperature of the DHT11 sensor. In tests that have been done lamps and fans can work properly. The lamp can turn on automatically when the light begins to darken, and the lamp can also turn off automatically when the light begins to bright again. In addition, it can concluded also that the readings of LDR sensors are placed outside the room is different from the readings of LDR sensors placed in the room. This is because the light intensity received by the existing LDR sensor in the room is blocked by the wall of the house or by other objects. Then for the fan, it can also turn on automatically when the temperature is greater than 25°C, and the fan speed can also be adjusted. The fan may also turn off automatically when the temperature is less than equal to 25°C.
ERIC Educational Resources Information Center
Yeni, Sabiha; Ozdener, Nesrin
2014-01-01
The purpose of the study is to investigate how pre-service teachers benefit from learning objects repositories while preparing course content. Qualitative and quantitative data collection methods were used in a mixed methods approach. This study was carried out with 74 teachers from the Faculty of Education. In the first phase of the study,…
Chameleon gravity, electrostatics, and kinematics in the outer galaxy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pourhasan, R.; Mann, R.B.; Afshordi, N.
2011-12-01
Light scalar fields are expected to arise in theories of high energy physics (such as string theory), and find phenomenological motivations in dark energy, dark matter, or neutrino physics. However, the coupling of light scalar fields to ordinary (or dark) matter is strongly constrained from laboratory, solar system, and astrophysical tests of the fifth force. One way to evade these constraints in dense environments is through the chameleon mechanism, where the field's mass steeply increases with ambient density. Consequently, the chameleonic force is only sourced by a thin shell near the surface of dense objects, which significantly reduces its magnitude.more » In this paper, we argue that thin-shell conditions are equivalent to ''conducting'' boundary conditions in electrostatics. As an application, we use the analogue of the method of images to calculate the back-reaction (or self-force) of an object around a spherical gravitational source. Using this method, we can explicitly compute the violation of the equivalence principle in the outskirts of galactic haloes (assuming an NFW dark matter profile): Intermediate mass satellites can be slower than their larger/smaller counterparts by as much as 10% close to a thin shell.« less
Hybrid plasmonic nanodevices: Switching mechanism for the nonlinear emission
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bragas, Andrea V.; Singh, Mahi R.
2014-03-31
Control of the light emission at the nanoscale is of central interest in nanophotonics due to the many applications in very different fields, ranging from quantum information to biophysics. Resonant excitation of surface plasmon polaritons in metal nanoparticles create nanostructured and enhanced light fields around those structures, which produce their strong interaction in a hybrid nanodevice with other plasmonic or non-plasmonic objects. This interaction may in turn also modulate the far field with important consequences in the applications. We show in this paper that the nonlinear emission from semiconductor quantum dots is strongly affected by the close presence of metalmore » nanoparticles, which are resonantly excited. Using a pulsed laser, optical second harmonic is generated in the quantum dot, and it is highly enhanced when the laser is tuned around the nanoparticle plasmon resonance. Even more interesting is the demonstration of a switching mechanism, controlled by an external continuous-wave field, which can enhance or extinguish the SH signal, even when the pulsed laser is always on. Experimental observations are in excellent agreement with the theoretical calculations, based on the dipole-dipole near-field coupling of the objects forming the hybrid system.« less
Simulation of optical interstellar scintillation
NASA Astrophysics Data System (ADS)
Habibi, F.; Moniez, M.; Ansari, R.; Rahvar, S.
2013-04-01
Aims: Stars twinkle because their light propagates through the atmosphere. The same phenomenon is expected on a longer time scale when the light of remote stars crosses an interstellar turbulent molecular cloud, but it has never been observed at optical wavelengths. The aim of the study described in this paper is to fully simulate the scintillation process, starting from the molecular cloud description as a fractal object, ending with the simulations of fluctuating stellar light curves. Methods: Fast Fourier transforms are first used to simulate fractal clouds. Then, the illumination pattern resulting from the crossing of background star light through these refractive clouds is calculated from a Fresnel integral that also uses fast Fourier transform techniques. Regularisation procedure and computing limitations are discussed, along with the effect of spatial and temporal coherency (source size and wavelength passband). Results: We quantify the expected modulation index of stellar light curves as a function of the turbulence strength - characterised by the diffraction radius Rdiff - and the projected source size, introduce the timing aspects, and establish connections between the light curve observables and the refractive cloud. We extend our discussion to clouds with different structure functions from Kolmogorov-type turbulence. Conclusions: Our study confirms that current telescopes of ~4 m with fast-readout, wide-field detectors have the capability of discovering the first interstellar optical scintillation effects. We also show that this effect should be unambiguously distinguished from any other type of variability through the observation of desynchronised light curves, simultaneously measured by two distant telescopes.
Estimation of crosstalk in LED fNIRS by photon propagation Monte Carlo simulation
NASA Astrophysics Data System (ADS)
Iwano, Takayuki; Umeyama, Shinji
2015-12-01
fNIRS (functional near-Infrared spectroscopy) can measure brain activity non-invasively and has advantages such as low cost and portability. While the conventional fNIRS has used laser light, LED light fNIRS is recently becoming common in use. Using LED for fNIRS, equipment can be more inexpensive and more portable. LED light, however, has a wider illumination spectrum than laser light, which may change crosstalk between the calculated concentration change of oxygenated and deoxygenated hemoglobins. The crosstalk is caused by difference in light path length in the head tissues depending on wavelengths used. We conducted Monte Carlo simulations of photon propagation in the tissue layers of head (scalp, skull, CSF, gray matter, and white matter) to estimate the light path length in each layers. Based on the estimated path lengths, the crosstalk in fNIRS using LED light was calculated. Our results showed that LED light more increases the crosstalk than laser light does when certain combinations of wavelengths were adopted. Even in such cases, the crosstalk increased by using LED light can be effectively suppressed by replacing the value of extinction coefficients used in the hemoglobin calculation to their weighted average over illumination spectrum.
SU-C-207A-03: Development of Proton CT Imaging System Using Thick Scintillator and CCD Camera
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tanaka, S; Uesaka, M; Nishio, T
2016-06-15
Purpose: In the treatment planning of proton therapy, Water Equivalent Length (WEL), which is the parameter for the calculation of dose and the range of proton, is derived by X-ray CT (xCT) image and xCT-WEL conversion. However, about a few percent error in the accuracy of proton range calculation through this conversion has been reported. The purpose of this study is to construct a proton CT (pCT) imaging system for an evaluation of the error. Methods: The pCT imaging system was constructed with a thick scintillator and a cooled CCD camera, which acquires the two-dimensional image of integrated value ofmore » the scintillation light toward the beam direction. The pCT image is reconstructed by FBP method using a correction between the light intensity and residual range of proton beam. An experiment for the demonstration of this system was performed with 70-MeV proton beam provided by NIRS cyclotron. The pCT image of several objects reconstructed from the experimental data was evaluated quantitatively. Results: Three-dimensional pCT images of several objects were reconstructed experimentally. A finestructure of approximately 1 mm was clearly observed. The position resolution of pCT image was almost the same as that of xCT image. And the error of proton CT pixel value was up to 4%. The deterioration of image quality was caused mainly by the effect of multiple Coulomb scattering. Conclusion: We designed and constructed the pCT imaging system using a thick scintillator and a CCD camera. And the system was evaluated with the experiment by use of 70-MeV proton beam. Three-dimensional pCT images of several objects were acquired by the system. This work was supported by JST SENTAN Grant Number 13A1101 and JSPS KAKENHI Grant Number 15H04912.« less
Calculating observables in inhomogeneous cosmologies. Part I: general framework
NASA Astrophysics Data System (ADS)
Hellaby, Charles; Walters, Anthony
2018-02-01
We lay out a general framework for calculating the variation of a set of cosmological observables, down the past null cone of an arbitrarily placed observer, in a given arbitrary inhomogeneous metric. The observables include redshift, proper motions, area distance and redshift-space density. Of particular interest are observables that are zero in the spherically symmetric case, such as proper motions. The algorithm is based on the null geodesic equation and the geodesic deviation equation, and it is tailored to creating a practical numerical implementation. The algorithm provides a method for tracking which light rays connect moving objects to the observer at successive times. Our algorithm is applied to the particular case of the Szekeres metric. A numerical implementation has been created and some results will be presented in a subsequent paper. Future work will explore the range of possibilities.
Vasilakaki, Sofia; Barbayianni, Efrosini; Leonis, Georgios; Papadopoulos, Manthos G.; Mavromoustakos, Thomas; Gelb, Michael H.; Kokotos, George
2016-01-01
Inhibition of group IIA secreted phospholipase A2 (GIIA sPLA2) has been an important objective for medicinal chemists. We have previously shown that inhibitors incorporating the 2-oxoamide functionality may inhibit human and mouse GIIA sPLA2s. Herein, the development of new potent inhibitors by molecular docking calculations using the structure of the known inhibitor 7 as scaffold, are described. Synthesis and biological evaluation of the new compounds revealed that the long chain 2-oxoamide based on (S)-valine GK241 led to improved activity (IC50 = 143 nM and 68 nM against human and mouse GIIA sPLA2, respectively). In addition, molecular dynamics simulations were employed to shed light on GK241 potent and selective inhibitory activity. PMID:26970660
NASA Technical Reports Server (NTRS)
Colquitt, Walter
1989-01-01
The main objective is to improve the performance of a specific FORTRAN computer code from the Planetary Sciences Division of NASA/Johnson Space Center when used on a modern vectorizing supercomputer. The code is used to calculate orbits of dust grains that separate from comets and asteroids. This code accounts for influences of the sun and 8 planets (neglecting Pluto), solar wind, and solar light pressure including Poynting-Robertson drag. Calculations allow one to study the motion of these particles as they are influenced by the Earth or one of the other planets. Some of these particles become trapped just beyond the Earth for long periods of time. These integer period resonances vary from 3 orbits of the Earth and 2 orbits of the particles to as high as 14 to 13.
Radiometric calibration and SNR calculation of a SWIR imaging telescope
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yilmaz, Ozgur; Turk, Fethi; Selimoglu, Ozgur
2012-09-06
Radiometric calibration of an imaging telescope is usually made using a uniform illumination sphere in a laboratory. In this study, we used the open-sky images taken during bright day conditions to calibrate our telescope. We found a dark signal offset value and a linear response coefficient value for each pixel by using three different algorithms. Then we applied these coefficients to the taken images, and considerably lowered the image non-uniformity. Calibration can be repeated during the operation of telescope with an object that has better uniformity than open-sky. Also SNR (Signal to Noise Ratio) of each pixel was calculated frommore » the open-sky images using the temporal mean and standard deviations. It is found that SNR is greater than 80 for all pixels even at low light levels.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Choi, Yunhee; Lee, Jeong-Eun; Bourke, Tyler L.
We present observations and analyses of the low-mass star-forming region, Taurus Molecular Cloud-1 (TMC-1). CS ( J = 2–1)/N{sub 2}H{sup +} ( J = 1–0) and C{sup 17}O ( J = 2–1)/C{sup 18}O ( J = 2–1) were observed with the Five College Radio Astronomy Observatory and the Seoul Radio Astronomy Observatory, respectively. In addition, Spitzer infrared data and 1.2 mm continuum data observed with Max-Planck Millimetre Bolometer are used. We also perform chemical modeling to investigate the relative molecular distributions of the TMC-1 filament. Based on Spitzer observations, there is no young stellar object along the TMC-1 filament, while five Classmore » II and one Class I young stellar objects are identified outside the filament. The comparison between column densities calculated from dust continuum and C{sup 17}O 2–1 line emission shows that CO is depleted much more significantly in the ammonia peak than in the cyanopolyyne peak, while the column densities calculated from the dust continuum are similar at the two peaks. N{sub 2}H{sup +} is not depleted much in either peak. According to our chemical calculation, the differential chemical distribution in the two peaks can be explained by different timescales required to reach the same density, i.e., by different dynamical processes.« less
Identification and restoration in 3D fluorescence microscopy
NASA Astrophysics Data System (ADS)
Dieterlen, Alain; Xu, Chengqi; Haeberle, Olivier; Hueber, Nicolas; Malfara, R.; Colicchio, B.; Jacquey, Serge
2004-06-01
3-D optical fluorescent microscopy becomes now an efficient tool for volumic investigation of living biological samples. The 3-D data can be acquired by Optical Sectioning Microscopy which is performed by axial stepping of the object versus the objective. For any instrument, each recorded image can be described by a convolution equation between the original object and the Point Spread Function (PSF) of the acquisition system. To assess performance and ensure the data reproducibility, as for any 3-D quantitative analysis, the system indentification is mandatory. The PSF explains the properties of the image acquisition system; it can be computed or acquired experimentally. Statistical tools and Zernike moments are shown appropriate and complementary to describe a 3-D system PSF and to quantify the variation of the PSF as function of the optical parameters. Some critical experimental parameters can be identified with these tools. This is helpful for biologist to define an aquisition protocol optimizing the use of the system. Reduction of out-of-focus light is the task of 3-D microscopy; it is carried out computationally by deconvolution process. Pre-filtering the images improves the stability of deconvolution results, now less dependent on the regularization parameter; this helps the biologists to use restoration process.
Analyte stability during the total testing process: studies of vitamins A, D and E by LC-MS/MS.
Albahrani, Ali A; Rotarou, Victor; Roche, Peter J; Greaves, Ronda F
2016-10-01
There are limited evidence based studies demonstrating the stability of fat-soluble vitamins (FSV) measured in blood. This study aimed to examine the effects of light, temperature and time on vitamins A, D and E throughout the total testing process. Four experiments were conducted. Three investigated the sample matrix, of whole blood, serum and the extracted sample, against the variables of temperature and light; and the fourth experiment investigated the sample during the extraction process against the variable of light. All samples were analysed via our simultaneous FSV method using liquid chromatography-tandem mass spectrometry technology. The allowable clinical percentage change was calculated based on biological variation and desirable method imprecision for each analyte. The total change limit was ±7.3% for 25-OH-vitamin D3, ±11.8% for retinol and ±10.8% for α-tocopherol. Vitamins D and E were stable in the investigated conditions (concentration changes <4%) in the pre-analytical and analytical stages. Vitamin A showed photosensitivity in times >48 h with concentration changes of -6.8% (blood) and -6.5% (serum), both are within the allowable clinical percentage change. By contrast, the extracted retinol sample demonstrated a concentration change of -18.4% after 48 h of light exposure. However, vitamin A in the serum and extracted solution was stable for one month when stored at -20°C. Blood samples for vitamins D and E analyses can be processed in normal laboratory conditions of lighting and temperature. The required conditions for vitamin A analysis are similar when performed within 48 h. For longer-term storage, serum and vitamin A extracts should be stored at -20°C.
Matsushima, Hiroyuki; Nagata, Mayumi; Katsuki, Yoko; Ota, Ichiro; Miyake, Kensaku; Beiko, George H.H.; Grzybowski, Andrzej
2015-01-01
Background To report on five patients with decreased visual acuity due to glistening and severe sub-surface nano-glistening (SSNG) formation within their intraocular lenses (IOLs). Design Case reports and analysis of extracted IOLs. Participants and samples We report improved visual acuity when IOLs with severe glistening and SSNG were exchanged for clear IOLs in five patients. Methods Case reports. Main outcome measures The main outcome measure was visual acuity. The secondary outcome measure was light transmission. Explanted IOLs were subjected to investigation. Pre- and postoperative slit lamp images of the anterior eye and microscopic images of the extracted IOLs were taken and compared. Light transmission of the IOL was measured using a double beam type spectrophotometer. An integrated value of the percentage light transmittance in the visible light spectrum was calculated. Results We report on five patients whose visual acuity improved when IOLs were exchanged because of severe glistening and SSNG. All of the affected IOLs were MA60BM (Alcon, Forth Wroth Texas, USA) and the original implantation had occurred over a range of 6–15 years prior to the IOL exchange. Light transmission was decreased in all affected lenses compared to a similar control IOL. Conclusions Although only a few reports of cases in which glistening and SSNG have progressed to the level of decreased visual function have been published, the likelihood is that this phenomena will increase as the severity and incidence of these inclusions have been shown to increase with time. Appropriate evaluations of visual function in such patients are needed and consideration should be given to IOL exchange in symptomatic patients. PMID:26586975
NASA Astrophysics Data System (ADS)
Zhou, Y.
2017-12-01
The rainfall associated with TCs making landfall over western Gulf Coast and Caribbean Sea Coast caused numerous fatalities and divesting damage, however, few studies have been done over these regions. This study examines spatial pattern of rain fields associated with TCs making landfall over western Gulf Coast and Caribbean Sea Coast during 1998-2015 through a Geographic Information System (GIS)-based analysis of satellite-estimated rain rates. Regions of light rainfall (rain rate > 2.5 mm/h) and moderate rainfall (rain rate > 5.0 mm/h) during entire life cycle of each TC are converted into polygons and measurements are made of their area, dispersion and displacement during entire life cycle. The metric of dispersion is calculated for the entire rain field as defined by outlining light and moderate rain rates. The displacement to east and north is calculated by area weighted methods. There are three main objectives of this study. The first goal is to measure the area and spatial distribution of rain fields of TCs making landfall over the western Gulf and Caribbean Sea coastlines. We examine in which regions, the light and moderate rainfall area, dispersion and displacement of rainfall have higher values, and how they change during the entire TC life cycle. The second goal is to determine to determine which environmental conditions are associated with the spatial configuration of light and moderate rain rates. The conditions include storm intensity, motion direction and speed, total precipitable water and wind shear. Last, we determine the time that rainfall reaches land relative to the time that the storm's center makes landfall and durations of rainfall from TCs over land.
Models of bright nickel-free supernovae from stripped massive stars with circumstellar shells
NASA Astrophysics Data System (ADS)
Kleiser, Io K. W.; Kasen, Daniel; Duffell, Paul C.
2018-04-01
The nature of an emerging class of rapidly fading supernovae (RFSNe) - characterized by their short-lived light-curve duration, but varying widely in peak brightness - remains puzzling. Whether the RFSNe arise from low-mass thermonuclear eruptions on white dwarfs or from the core collapse of massive stars is still a matter of dispute. We explore the possibility that the explosion of hydrogen-free massive stars could produce bright but rapidly fading transients if the effective pre-supernova radii are large and if little or no radioactive nickel is ejected. The source of radiation is then purely due to shock cooling. We study this model of RFSNe using spherically symmetric hydrodynamics and radiation transport calculations of the explosion of stripped stars embedded in helium-dominated winds or shells of various masses and extent. We present a parameter study showing how the properties of the circumstellar envelopes affect the dynamics of the explosion and can lead to a diversity of light curves. We also explore the dynamics of the fallback of the innermost stellar layers, which might be able to remove radioactive nickel from the ejecta, making the rapid decline in the late-time light curve possible. We provide scaling relations that describe how the duration and luminosity of these events depend on the supernova kinetic energy and the mass and radius of the circumstellar material.
NASA Astrophysics Data System (ADS)
Besemer, Abigail E.
Targeted radionuclide therapy is emerging as an attractive treatment option for a broad spectrum of tumor types because it has the potential to simultaneously eradicate both the primary tumor site as well as the metastatic disease throughout the body. Patient-specific absorbed dose calculations for radionuclide therapies are important for reducing the risk of normal tissue complications and optimizing tumor response. However, the only FDA approved software for internal dosimetry calculates doses based on the MIRD methodology which estimates mean organ doses using activity-to-dose scaling factors tabulated from standard phantom geometries. Despite the improved dosimetric accuracy afforded by direct Monte Carlo dosimetry methods these methods are not widely used in routine clinical practice because of the complexity of implementation, lack of relevant standard protocols, and longer dose calculation times. The main goal of this work was to develop a Monte Carlo internal dosimetry platform in order to (1) calculate patient-specific voxelized dose distributions in a clinically feasible time frame, (2) examine and quantify the dosimetric impact of various parameters and methodologies used in 3D internal dosimetry methods, and (3) develop a multi-criteria treatment planning optimization framework for multi-radiopharmaceutical combination therapies. This platform utilizes serial PET/CT or SPECT/CT images to calculate voxelized 3D internal dose distributions with the Monte Carlo code Geant4. Dosimetry can be computed for any diagnostic or therapeutic radiopharmaceutical and for both pre-clinical and clinical applications. In this work, the platform's dosimetry calculations were successfully validated against previously published reference doses values calculated in standard phantoms for a variety of radionuclides, over a wide range of photon and electron energies, and for many different organs and tumor sizes. Retrospective dosimetry was also calculated for various pre-clinical and clinical patients and large dosimetric differences resulted when using conventional organ-level methods and the patient-specific voxelized methods described in this work. The dosimetric impact of various steps in the 3D voxelized dosimetry process were evaluated including quantitative imaging acquisition, image coregistration, voxel resampling, ROI contouring, CT-based material segmentation, and pharmacokinetic fitting. Finally, a multi-objective treatment planning optimization framework was developed for multi-radiopharmaceutical combination therapies.
NASA Astrophysics Data System (ADS)
Berthier, J.; Carry, B.; Vachier, F.; Eggl, S.; Santerne, A.
2016-05-01
All the fields of the extended space mission Kepler/K2 are located within the ecliptic. Many Solar system objects thus cross the K2 stellar masks on a regular basis. We aim at providing to the entire community a simple tool to search and identify Solar system objects serendipitously observed by Kepler. The sky body tracker (SkyBoT) service hosted at Institut de mécanique céleste et de calcul des éphémérides provides a Virtual Observatory compliant cone search that lists all Solar system objects present within a field of view at a given epoch. To generate such a list in a timely manner, ephemerides are pre-computed, updated weekly, and stored in a relational data base to ensure a fast access. The SkyBoT web service can now be used with Kepler. Solar system objects within a small (few arcminutes) field of view are identified and listed in less than 10 s. Generating object data for the entire K2 field of view (14°) takes about a minute. This extension of the SkyBoT service opens new possibilities with respect to mining K2 data for Solar system science, as well as removing Solar system objects from stellar photometric time series.
Orlovic, Martina; Carter, Alexander William; Marti, Joachim; Mossialos, Elias
2017-01-01
Objective Obstetric care is a high-risk area in healthcare delivery, so it is essential to have up-to-date quantitative evidence in this area to inform policy decisions regarding these services. In light of this, the objective of this study is to investigate the incidence and economic burden of third and fourth-degree lacerations in the English National Health Service (NHS) using recent national data. Methods We used coded inpatient data from Hospital Episode Statistics (HES) for the financial years from 2010/2011 to 2013/2014 for all females that gave birth during that period in the English NHS. Using HES, we used pre-existing safety indicator algorithms to calculate the incidence of third and fourth-degree obstetric tears and employed a propensity score matching method to estimate the excess length of stay and economic burden associated with these events. Results Observed rates per 1000 inpatient episodes in 2010/2011 and 2013/2014, respectively: Patient Safety Indicator—trauma during vaginal delivery with instrument (PSI 18)=84.16 and 91.24; trauma during vaginal delivery without instrument (PSI 19)=29.78 and 33.43; trauma during caesarean delivery (PSI 20)=3.61 and 4.56. Estimated overall (all PSIs) economic burden for 2010/2011=£10.7 million and for 2013/2014=£14.5 million, expressed in 2013/2014 prices. Conclusions Despite many initiatives targeting the quality of maternity care in the NHS, the incidence of third and fourth-degree lacerations has increased during the observed period which signals that quality improvement efforts in obstetric care may not be reducing incidence rates. Our conservative estimates of the financial burden of these events appear low relative to total NHS expenditure for these years. PMID:28606903
30 CFR 5.30 - Fee calculation.
Code of Federal Regulations, 2010 CFR
2010-07-01
... authorizes the fee estimate. (1) The applicant may pre-authorize an expenditure for services under this subchapter, and may further choose to pre-authorize either a maximum dollar amount or an expenditure without a specified maximum amount. All applications containing a pre-authorization statement will...
30 CFR 5.30 - Fee calculation.
Code of Federal Regulations, 2013 CFR
2013-07-01
... authorizes the fee estimate. (1) The applicant may pre-authorize an expenditure for services under this subchapter, and may further choose to pre-authorize either a maximum dollar amount or an expenditure without a specified maximum amount. All applications containing a pre-authorization statement will...
30 CFR 5.30 - Fee calculation.
Code of Federal Regulations, 2011 CFR
2011-07-01
... authorizes the fee estimate. (1) The applicant may pre-authorize an expenditure for services under this subchapter, and may further choose to pre-authorize either a maximum dollar amount or an expenditure without a specified maximum amount. All applications containing a pre-authorization statement will...
Searching for δ Scuti-type pulsation and characterising northern pre-main-sequence field stars
NASA Astrophysics Data System (ADS)
Díaz-Fraile, D.; Rodríguez, E.; Amado, P. J.
2014-08-01
Context. Pre-main-sequence (PMS) stars are objects evolving from the birthline to the zero-age main sequence (ZAMS). Given a mass range near the ZAMS, the temperatures and luminosities of PMS and main-sequence stars are very similar. Moreover, their evolutionary tracks intersect one another causing some ambiguity in the determination of their evolutionary status. In this context, the detection and study of pulsations in PMS stars is crucial for differentiating between both types of stars by obtaining information of their interiors via asteroseismic techniques. Aims: A photometric variability study of a sample of northern field stars, which previously classified as either PMS or Herbig Ae/Be objects, has been undertaken with the purpose of detecting δ Scuti-type pulsations. Determination of physical parameters for these stars has also been carried out to locate them on the Hertzsprung-Russell diagram and check the instability strip for this type of pulsators. Methods: Multichannel photomultiplier and CCD time series photometry in the uvby Strömgren and BVI Johnson bands were obtained during four consecutive years from 2007 to 2010. The light curves have been analysed, and a variability criterion has been established. Among the objects classified as variable stars, we have selected those which present periodicities above 4 d-1, which was established as the lowest limit for δ Scuti-type pulsations in this investigation. Finally, these variable stars have been placed in a colour-magnitude diagram using the physical parameters derived with the collected uvbyβ Strömgren-Crawford photometry. Results: Five PMS δ Scuti- and three probable β Cephei-type stars have been detected. Two additional PMS δ Scuti stars are also confirmed in this work. Moreover, three new δ Scuti- and two γ Doradus-type stars have been detected among the main-sequence objects used as comparison or check stars.
Planning the FUSE Mission Using the SOVA Algorithm
NASA Technical Reports Server (NTRS)
Lanzi, James; Heatwole, Scott; Ward, Philip R.; Civeit, Thomas; Calvani, Humberto; Kruk, Jeffrey W.; Suchkov, Anatoly
2011-01-01
Three documents discuss the Sustainable Objective Valuation and Attainability (SOVA) algorithm and software as used to plan tasks (principally, scientific observations and associated maneuvers) for the Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. SOVA is a means of managing risk in a complex system, based on a concept of computing the expected return value of a candidate ordered set of tasks as a product of pre-assigned task values and assessments of attainability made against qualitatively defined strategic objectives. For the FUSE mission, SOVA autonomously assembles a week-long schedule of target observations and associated maneuvers so as to maximize the expected scientific return value while keeping the satellite stable, managing the angular momentum of spacecraft attitude- control reaction wheels, and striving for other strategic objectives. A six-degree-of-freedom model of the spacecraft is used in simulating the tasks, and the attainability of a task is calculated at each step by use of strategic objectives as defined by use of fuzzy inference systems. SOVA utilizes a variant of a graph-search algorithm known as the A* search algorithm to assemble the tasks into a week-long target schedule, using the expected scientific return value to guide the search.
Near-Field Scanning Optical Microscopy and Raman Microscopy.
NASA Astrophysics Data System (ADS)
Harootunian, Alec Tate
1987-09-01
Both a one dimensional near-field scanning optical microscope and Raman microprobe were constructed. In near -field scanning optical microscopy (NSOM) a subwavelength aperture is scanned in the near-field of the object. Radiation transmitted through the aperture is collected to form an image as the aperture scans over the object. The resolution of an NSOM system is essentially wavelength independent and is limited by the diameter of the aperture used to scan the object. NSOM was developed in an effort to provide a nondestructive in situ high spatial resolution probe while still utilizing photons at optical wavelengths. The Raman microprobe constructed provided vibrational Raman information with spatial resolution equivalent that of a conventional diffraction limited microscope. Both transmission studies and near-field diffration studies of subwavelength apertures were performed. Diffraction theories for a small aperture in an infinitely thin conducting screen, a slit in a thick conducting screen, and an aperture in a black screen were examined. All three theories indicate collimation of radiation to the size to the size of the subwavelength aperture or slit in the near-field. Theoretical calculations and experimental results indicate that light transmitted through subwavelength apertures is readily detectable. Light of wavelength 4579 (ANGSTROM) was transmitted through apertures with diameters as small as 300 (ANGSTROM). These studies indicate the feasibility of constructing an NSOM system. One dimensional transmission and fluorescence NSOM systems were constructed. Apertures in the tips of metallized glass pipettes width inner diameters of less than 1000 (ANGSTROM) were used as a light source in the NSOM system. A tunneling current was used to maintain the aperture position in the near-field. Fluorescence NSOM was demonstrated for the first time. Microspectroscopic and Raman microscopic studies of turtle cone oil droplets were performed. Both the Raman vibrational frequencies and the Raman excitation data indicate that the carotenoids are unaggregated. The carotenoid astaxanthin was identified in the orange and red droplets by Raman microscopy. Future applications for both Raman microscopy and near-field microscopy were proposed. Four methods of near-field distance regulation were also examined. Finally, theoretical exposure curves for near-field lithography were calculated. Both the near-field lithographic results and the near field diffraction studies indicate essentially wavelength independent resolution. (Abstract shortened with permission of author.).
Kay, Daniel B; Buysse, Daniel J; Germain, Anne; Hall, Martica; Monk, Timothy H
2015-02-01
Discrepancy between subjective and objective measures of sleep is associated with insomnia and increasing age. Cognitive behavioural therapy for insomnia improves sleep quality and decreases subjective-objective sleep discrepancy. This study describes differences between older adults with insomnia and controls in sleep discrepancy, and tests the hypothesis that reduced sleep discrepancy following cognitive behavioural therapy for insomnia correlates with the magnitude of symptom improvement reported by older adults with insomnia. Participants were 63 adults >60 years of age with insomnia, and 51 controls. At baseline, participants completed sleep diaries for 7 days while wearing wrist actigraphs. After receiving cognitive behavioural therapy for insomnia, insomnia patients repeated this sleep assessment. Sleep discrepancy variables were calculated by subtracting actigraphic sleep onset latency and wake after sleep onset from respective self-reported estimates, pre- and post-treatment. Mean level and night-to-night variability in sleep discrepancy were investigated. Baseline sleep discrepancies were compared between groups. Pre-post-treatment changes in Insomnia Severity Index score and sleep discrepancy variables were investigated within older adults with insomnia. Sleep discrepancy was significantly greater and more variable across nights in older adults with insomnia than controls, P ≤ 0.001 for all. Treatment with cognitive behavioural therapy for insomnia was associated with significant reduction in the Insomnia Severity Index score that correlated with changes in mean level and night-to-night variability in wake after sleep onset discrepancy, P < 0.001 for all. Study of sleep discrepancy patterns may guide more targeted treatments for late-life insomnia. © 2014 European Sleep Research Society.
Curcumin uptake enhancement using low dose light illumination during incubation in Candida albicans
NASA Astrophysics Data System (ADS)
Romano, Renan A.; Pratavieira, Sebastião.; da Silva, Ana P.; Kurachi, Cristina; Bagnato, Vanderlei S.; Guimarães, Francisco E. G.
2017-07-01
A new PDI protocol is presented in this study. C. albicans cells pre-illuminated with a low dose light demonstrated an increase of curcumin uptake when compared to dark incubation, leading to a higher PDI efficacy.
Hard exclusive pion electroproduction at backward angles with CLAS
NASA Astrophysics Data System (ADS)
Park, K.; Guidal, M.; Gothe, R. W.; Pire, B.; Semenov-Tian-Shansky, K.; Laget, J.-M.; Adhikari, K. P.; Adhikari, S.; Akbar, Z.; Avakian, H.; Ball, J.; Balossino, I.; Baltzell, N. A.; Barion, L.; Battaglieri, M.; Bedlinskiy, I.; Biselli, A. S.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Cao, F. T.; Carman, D. S.; Celentano, A.; Charles, G.; Chetry, T.; Ciullo, G.; Clark, L.; Cole, P. L.; Contalbrigo, M.; Crede, V.; D'Angelo, A.; Dashyan, N.; De Vita, R.; De Sanctis, E.; Defurne, M.; Deur, A.; Djalali, C.; Dupre, R.; Egiyan, H.; El Alaoui, A.; El Fassi, L.; Elouadrhiri, L.; Eugenio, P.; Fedotov, G.; Fersch, R.; Filippi, A.; Garçon, M.; Ghandilyan, Y.; Gilfoyle, G. P.; Girod, F. X.; Golovatch, E.; Griffioen, K. A.; Guo, L.; Hafidi, K.; Hakobyan, H.; Hanretty, C.; Harrison, N.; Hattawy, M.; Heddle, D.; Hicks, K.; Holtrop, M.; Hyde, C. E.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Isupov, E. L.; Jenkins, D.; Johnston, S.; Joo, K.; Kabir, M. L.; Keller, D.; Khachatryan, G.; Khachatryan, M.; Khandaker, M.; Kim, W.; Klein, F. J.; Kubarovsky, V.; Kuhn, S. E.; Lanza, L.; Livingston, K.; MacGregor, I. J. D.; Markov, N.; McKinnon, B.; Mirazita, M.; Mokeev, V.; Montgomery, R. A.; Munoz Camacho, C.; Nadel-Turonski, P.; Niccolai, S.; Niculescu, G.; Osipenko, M.; Paolone, M.; Paremuzyan, R.; Pasyuk, E.; Phelps, W.; Pogorelko, O.; Poudel, J.; Price, J. W.; Prok, Y.; Protopopescu, D.; Ripani, M.; Rizzo, A.; Rossi, P.; Sabatié, F.; Salgado, C.; Schumacher, R. A.; Sharabian, Y.; Skorodumina, Iu.; Smith, G. D.; Sokhan, D.; Sparveris, N.; Stepanyan, S.; Strakovsky, I. I.; Strauch, S.; Taiuti, M.; Tan, J. A.; Ungaro, M.; Voskanyan, H.; Voutier, E.; Wei, X.; Zachariou, N.; Zhang, J.
2018-05-01
We report on the first measurement of cross sections for exclusive deeply virtual pion electroproduction off the proton, ep →e‧ nπ+, above the resonance region at backward pion center-of-mass angles. The φπ* -dependent cross sections were measured, from which we extracted three combinations of structure functions of the proton. Our results are compatible with calculations based on nucleon-to-pion transition distribution amplitudes (TDAs). These non-perturbative objects are defined as matrix elements of three-quark-light-cone-operators and characterize partonic correlations with a particular emphasis on baryon charge distribution inside a nucleon.
Lunar eclipse photometry: absolute luminance measurements and modeling.
Hernitschek, Nina; Schmidt, Elmar; Vollmer, Michael
2008-12-01
The Moon's time-dependent luminance was determined during the 9 February 1990 and 3 March 2007 total lunar eclipses by using calibrated, industry standard photometers. After the results were corrected to unit air mass and to standard distances for both Moon and Sun, an absolute calibration was accomplished by using the Sun's known luminance and a pre-eclipse lunar albedo of approximately 13.5%. The measured minimum level of brightness in the total phase of both eclipses was relatively high, namely -3.32 m(vis) and -1.7 m(vis), which hints at the absence of pronounced stratospheric aerosol. The light curves were modeled in such a way as to let the Moon move through an artificial Earth shadow composed of a multitude of disk and ring zones, containing a relative luminance data set from an atmospheric radiative transfer calculation.
Response Time Measurements of the NIF DANTE XRD-31 X-Ray Diodes (Pre-print)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Don Pellinen and Michael Griffin
2009-01-23
The XRD-31 is a fast, windowless X-ray vacuum photodiode developed by EG&G. It is currently the primary fast X-ray detector used to diagnose the X-rays on NIF and OMEGA on the multichannel DANTE spectrometer. The XRD-31 has a dynamic range of less than 1e-12 amps to more than 10 amps. A technique is described to measure the impulse response of the diodes to a 150 fs pulse of 200 nm laser light and a method to calculate the “risetime” for a square pulse and compare it with the computed electron transit time from the photocathode to the anode. Measured responsemore » time for 5 XRD-31s assembled in early 2004 was 149.7 ps +-2.75 ps.« less
Gravitational particle production in inflation. A fresh look
NASA Astrophysics Data System (ADS)
Yajnik, Urjit A.
1990-01-01
Gravitational production of energy density in the case of a minimally coupled scalar field is treated using quantum field theory in curved spacetime. We calculate
Zivcevska, Marija; Lei, Shaobo; Blakeman, Alan; Goltz, Herbert C; Wong, Agnes M F
2018-03-01
To develop an objective psychophysical method to quantify light-induced visual discomfort, and to measure the effects of viewing condition and stimulus wavelength. Eleven visually normal subjects participated in the study. Their pupils were dilated (2.5% phenylephrine) before the experiment. A Ganzfeld system presented either red (1.5, 19.1, 38.2, 57.3, 76.3, 152.7, 305.3 cd/m2) or blue (1.4, 7.1, 14.3, 28.6, 42.9, 57.1, 71.4 cd/m2) randomized light intensities (1 s each) in four blocks. Constant white-light stimuli (3 cd/m2, 4 s duration) were interleaved with the chromatic trials. Participants reported each stimulus as either "uncomfortably bright" or "not uncomfortably bright." The experiment was done binocularly and monocularly in separate sessions, and the order of color/viewing condition sequence was randomized across participants. The proportion of "uncomfortable" responses was used to generate individual psychometric functions, from which 50% discomfort thresholds were calculated. Light-induced discomfort was higher under blue compared with red light stimulation, both during binocular (t(10) = 3.58, P < 0.01) and monocular viewing (t(10) = 3.15, P = 0.01). There was also a significant difference in discomfort between viewing conditions, with binocular viewing inducing more discomfort than monocular viewing for blue (P < 0.001), but not for red light stimulation. The light-induced discomfort characteristics reported here are consistent with features of the melanopsin-containing intrinsically photosensitive retinal ganglion cell light irradiance pathway, which may mediate photophobia, a prominent feature in many clinical disorders. This is the first psychometric assessment designed around melanopsin spectral properties that can be customized further to assess photophobia in different clinical populations.
Farno, Ehsan; Baudez, Jean Christophe; Parthasarathy, Rajarathinam; Eshtiaghi, Nicky
2017-04-16
In a wastewater treatment process, energy is mainly used in sludge handling and heating, while energy is recovered by biogas production in anaerobic digestion process. Thermal pre-treatment of sludge can change the energy balance in a wastewater treatment process since it reduces the viscosity and yield stress of sludge and increases the biogas production. In this study, a calculation based on a hypothetical wastewater treatment plant is provided to show the possibility of creating a net positive energy wastewater treatment plant as a result of implementing thermal pre-treatment process before the anaerobic digester. The calculations showed a great energy saving in pumping and mixing of the sludge by thermal pre-treatment of sludge before anaerobic digestion process.
Light water reactor lower head failure analysis
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rempe, J.L.; Chavez, S.A.; Thinnes, G.L.
1993-10-01
This document presents the results from a US Nuclear Regulatory Commission-sponsored research program to investigate the mode and timing of vessel lower head failure. Major objectives of the analysis were to identify plausible failure mechanisms and to develop a method for determining which failure mode would occur first in different light water reactor designs and accident conditions. Failure mechanisms, such as tube ejection, tube rupture, global vessel failure, and localized vessel creep rupture, were studied. Newly developed models and existing models were applied to predict which failure mechanism would occur first in various severe accident scenarios. So that a broadermore » range of conditions could be considered simultaneously, calculations relied heavily on models with closed-form or simplified numerical solution techniques. Finite element techniques-were employed for analytical model verification and examining more detailed phenomena. High-temperature creep and tensile data were obtained for predicting vessel and penetration structural response.« less
Retinex based low-light image enhancement using guided filtering and variational framework
NASA Astrophysics Data System (ADS)
Zhang, Shi; Tang, Gui-jin; Liu, Xiao-hua; Luo, Su-huai; Wang, Da-dong
2018-03-01
A new image enhancement algorithm based on Retinex theory is proposed to solve the problem of bad visual effect of an image in low-light conditions. First, an image is converted from the RGB color space to the HSV color space to get the V channel. Next, the illuminations are respectively estimated by the guided filtering and the variational framework on the V channel and combined into a new illumination by average gradient. The new reflectance is calculated using V channel and the new illumination. Then a new V channel obtained by multiplying the new illumination and reflectance is processed with contrast limited adaptive histogram equalization (CLAHE). Finally, the new image in HSV space is converted back to RGB space to obtain the enhanced image. Experimental results show that the proposed method has better subjective quality and objective quality than existing methods.
Method of Modeling and Simulation of Shaped External Occulters
NASA Technical Reports Server (NTRS)
Lyon, Richard G. (Inventor); Clampin, Mark (Inventor); Petrone, Peter, III (Inventor)
2016-01-01
The present invention relates to modeling an external occulter including: providing at least one processor executing program code to implement a simulation system, the program code including: providing an external occulter having a plurality of petals, the occulter being coupled to a telescope; and propagating light from the occulter to a telescope aperture of the telescope by scalar Fresnel propagation, by: obtaining an incident field strength at a predetermined wavelength at an occulter surface; obtaining a field propagation from the occulter to the telescope aperture using a Fresnel integral; modeling a celestial object at differing field angles by shifting a location of a shadow cast by the occulter on the telescope aperture; calculating an intensity of the occulter shadow on the telescope aperture; and applying a telescope aperture mask to a field of the occulter shadow, and propagating the light to a focal plane of the telescope via FFT techniques.
Polarized Raman spectroscopy of bone tissue: watch the scattering
NASA Astrophysics Data System (ADS)
Raghavan, Mekhala; Sahar, Nadder D.; Wilson, Robert H.; Mycek, Mary-Ann; Pleshko, Nancy; Kohn, David H.; Morris, Michael D.
2010-02-01
Polarized Raman spectroscopy is widely used in the study of molecular composition and orientation in synthetic and natural polymer systems. Here, we describe the use of Raman spectroscopy to extract quantitative orientation information from bone tissue. Bone tissue poses special challenges to the use of polarized Raman spectroscopy for measurement of orientation distribution functions because the tissue is turbid and birefringent. Multiple scattering in turbid media depolarizes light and is potentially a source of error. Using a Raman microprobe, we show that repeating the measurements with a series of objectives of differing numerical apertures can be used to assess the contributions of sample turbidity and depth of field to the calculated orientation distribution functions. With this test, an optic can be chosen to minimize the systematic errors introduced by multiple scattering events. With adequate knowledge of the optical properties of these bone tissues, we can determine if elastic light scattering affects the polarized Raman measurements.
Axial-Current Matrix Elements in Light Nuclei from Lattice QCD
DOE Office of Scientific and Technical Information (OSTI.GOV)
Savage, Martin; Shanahan, Phiala E.; Tiburzi, Brian C.
2016-12-01
I present results from the first lattice QCD calculations of axial-current matrix elements in light nuclei, performed by the NPLQCD collaboration. Precision calculations of these matrix elements, and the subsequent extraction of multi-nucleon axial-current operators, are essential in refining theoretical predictions of the proton-proton fusion cross section, neutrino-nucleus cross sections andmore » $$\\beta\\beta$$-decay rates of nuclei. In addition, they are expected to shed light on the phenomenological quenching of $$g_A$$ that is required in nuclear many-body calculations.« less
Biosensors for EVA: Improved Instrumentation for Ground-based Studies
NASA Technical Reports Server (NTRS)
Soller, B.; Ellerby, G.; Zou, F.; Scott, P.; Jin, C.; Lee, S. M. C.; Coates, J.
2010-01-01
During lunar excursions in the EVA suit, real-time measurement of metabolic rate is required to manage consumables and guide activities to ensure safe return to the base. Metabolic rate, or oxygen consumption (VO2), is normally measured from pulmonary parameters but cannot be determined with standard techniques in the oxygen-rich environment of a spacesuit. Our group has developed novel near infrared spectroscopic (NIRS) methods to calculate muscle oxygen saturation (SmO 2), hematocrit, and pH, and we recently demonstrated that we can use our NIRS sensor to measure VO 2 on the leg during cycling. Our NSBRI project has 4 objectives: (1) increase the accuracy of the metabolic rate calculation through improved prediction of stroke volume; (2) investigate the relative contributions of calf and thigh oxygen consumption to metabolic rate calculation for walking and running; (3) demonstrate that the NIRS-based noninvasive metabolic rate methodology is sensitive enough to detect decrement in VO 2 in a space analog; and (4) improve instrumentation to allow testing within a spacesuit. Over the past year we have made progress on all four objectives, but the most significant progress was made in improving the instrumentation. The NIRS system currently in use at JSC is based on fiber optics technology. Optical fiber bundles are used to deliver light from a light source in the monitor to the patient, and light reflected back from the patient s muscle to the monitor for spectroscopic analysis. The fiber optic cables are large and fragile, and there is no way to get them in and out of the test spacesuit used for ground-based studies. With complimentary funding from the US Army, we undertook a complete redesign of the sensor and control electronics to build a novel system small enough to be used within the spacesuit and portable enough to be used by a combat medic. In the new system the filament lamp used in the fiber optic system was replaced with a novel broadband near infrared LED light source. The compact grating spectrometer was replaced with a chip-scale spectrometer. With this new design, the sensor is 4 in 2 in 0.5 in, weighs 60 g, and no fiber optic cables are needed. The sensor, which contains the light source and the spectrometer, is adhered directly to the skin with medical grade adhesive. The sensor can be powered via the USB port of the laptop computer that controls the sensor operation. Alternatively, for studies in the spacesuit, the sensor can be powered by a small battery pack and operated by an ultra-portable hand-held computer. Both the handheld computer and battery pack will easily fit within the PLSS of the test spacesuit. System automation was significantly improved, to add features suggested by our colleagues in the Cardiovascular Laboratory and the NASA JSC Exercise Physiology and Countermeasures Project. The functionality and portability of this system were demonstrated in our UMass laboratory.
Precise Selenodetic Coordinate System on Artificial Light Refers
NASA Astrophysics Data System (ADS)
Bagrov, Alexander; Pichkhadze, Konstantin M.; Sysoev, Valentin
Historically a coordinate system for the Moon was established on the base of telescopic observations from the Earth. As the angular resolution of Earth-to-Space telescopic observations is limited by Earth atmosphere, and is ordinary worse then 1 ang. second, the mean accuracy of selenodetic coordinates is some angular minutes, which corresponds to errors about 900 meters for positions of lunar objects near center of visible lunar disk, and at least twice more when objects are near lunar poles. As there are no Global Positioning System nor any astronomical observation instruments on the Moon, we proposed to use an autonomous light beacon on the Luna-Globe landing module to fix its position on the surface of the moon ant to use it as refer point for fixation of spherical coordinates system for the Moon. The light beacon is designed to be surely visible by orbiting probe TV-camera. As any space probe has its own stars-orientation system, there is not a problem to calculate a set of directions to the beacon and to the referent stars in probe-centered coordinate system during flight over the beacon. Large number of measured angular positions and time of each observation will be enough to calculate both orbital parameters of the probe and selenodetic coordinates of the beacon by methods of geodesy. All this will allow fixing angular coordinates of any feature of lunar surface in one global coordinate system, referred to the beacon. The satellite’s orbit plane contains ever the center mass of main body, so if the beacon will be placed closely to a lunar pole, we shall determine pole point position of the Moon with accuracy tens times better then it is known now. When angular accuracy of self-orientation by stars of the orbital module of Luna-Glob mission will be 6 angular seconds, then being in circular orbit with height of 200 km the on-board TV-camera will allow calculation of the beacon position as well as 6" corresponding to spatial resolution of the camera. It mean that coordinates of the beacon will be determined with accuracy not worse then 6 meters on the lunar surface. Much more accuracy can be achieved if orbital probe will use as precise angular measurer as optical interferometer. The limiting accuracy of proposed method is far above any reasonable level, because it may be sub-millimeter one. Theoretical analysis shows that for achievement of 1-meter accuracy of coordinate measuring over lunar globe it will be enough to disperse over it surface some 60 light beacons. Designed by Lavochkin Association light beacon is autonomous one, and it will work at least 10 years, so coordinate frame of any other lunar mission could use established selenodetic coordinates during this period. The same approach may be used for establishing Martial coordinates system.
Three-dimensional information extraction from GaoFen-1 satellite images for landslide monitoring
NASA Astrophysics Data System (ADS)
Wang, Shixin; Yang, Baolin; Zhou, Yi; Wang, Futao; Zhang, Rui; Zhao, Qing
2018-05-01
To more efficiently use GaoFen-1 (GF-1) satellite images for landslide emergency monitoring, a Digital Surface Model (DSM) can be generated from GF-1 across-track stereo image pairs to build a terrain dataset. This study proposes a landslide 3D information extraction method based on the terrain changes of slope objects. The slope objects are mergences of segmented image objects which have similar aspects; and the terrain changes are calculated from the post-disaster Digital Elevation Model (DEM) from GF-1 and the pre-disaster DEM from GDEM V2. A high mountain landslide that occurred in Wenchuan County, Sichuan Province is used to conduct a 3D information extraction test. The extracted total area of the landslide is 22.58 ha; the displaced earth volume is 652,100 m3; and the average sliding direction is 263.83°. The accuracies of them are 0.89, 0.87 and 0.95, respectively. Thus, the proposed method expands the application of GF-1 satellite images to the field of landslide emergency monitoring.
The pre-B cell receptor: turning autoreactivity into self-defense.
Vettermann, Christian; Jäck, Hans-Martin
2010-05-01
The first step in establishing the antibody repertoire in humans and mice is the rearrangement of immunoglobulin heavy chain (HC) genes in early B lineage cells. These cells then assemble microHCs with surrogate light chains (SLC) into a pre-B cell receptor (pre-BCR). We propose that the pre-BCR has evolved from an ancient autoreactive BCR, since the SLC is an autoreactive entity that binds to the pre-BCR itself and to other self-antigens. Abrogation of autoreactivity in the SLC diminishes pre-BCR signaling and impairs the clonal expansion of pre-B cells producing functional microHCs. Since SLC expression is restricted to pre-B cells, the autoreactivity encoded by the pre-BCR can be utilized to pre-select the antibody repertoire, while simultaneously avoiding the formation of autoreactive B lymphocytes. Copyright 2010 Elsevier Ltd. All rights reserved.
Seccia, V.; Cocuzza, P.; Ferrazza, P.; Briganti, T.; Matteucci, F.; Fatigante, L.; Giusti, P.; Grosso, M.; Locantore, L.; Morganti, R.; Nacci, A.; Sellari Franceschini, S.; Paiar, F.; Caramella, D.; Fattori, B.
2016-01-01
SUMMARY The objective of this study is to report the initial results of a prospective trial assessing instrumental deglutition function in nasopharynx and oropharynx cancers after radio or chemoradiotherapy using intensity-modulated radiotherapy (IMRT). IMRT was delivered aiming to spare the swallowing organ at risk (SWOARs) for Stage II-IV naso- and oropharynx cancer. Objective instrumental assessment included videofluoroscopy (VFS), fiberoptic endoscopic evaluation of swallowing (FEES) and oro-pharyngeal-oesophageal scintigraphy (OPES) at baseline and at 1 month after radiotherapy. Dysphagia parameter scores were calculated at each exam after liquid (L) and semi-liquid (SL) bolus intake: pre-deglutition penetration, aspiration, pharyngeal transit time (PTT) and hypopharyngeal retention index (HPRI). Overall, 20 patients (6 nasophaynx and 14 oropharynx) completed treatment and instrumental assessment after 1 month. Comparison between pre- and post-treatment HPRI score values showed a significant worsening in both FEES-L (p = 0.021) and SL (p = 0.02) and at VFS-L (p = 0.008) and SL (p = 0.005). Moreover, a relationship between HPRI worsening at FEES-L and FEES-SL (p = 0.005) as well as at VFS-L and VFS-SL (p < 0.001) was observed. PTT was not significantly affected by radiotherapy (p > 0.2). Only a few patients experienced pre-deglutition penetration (1 patient with base of tongue cancer at FEES-L and SL) and aspiration (1 patient with nasopharynx cancer at OPES-L and FEES-SL) after radiotherapy. Our early results showed that IMRT-SWOARs sparing caused a significant increase in the post-deglutition HPRI score. Longer follow-up will be necessary to evaluate if the increase of HPRI is related to a high risk of developing late aspiration. PMID:27070541
On the formation of TW Crv optical radiation
NASA Astrophysics Data System (ADS)
Shimansky, V. V.; Mitrofanova, A. A.; Borisov, N. V.; Fabrika, S. N.; Galeev, A. I.
2016-10-01
We present the analysis of the optical radiation of the young pre-cataclysmic variable TW Crv. Spectroscopic and photometric observations were obtained at the SAO RAS 6-m BTA telescope and at the Russian-Turkish RTT-150 telescope. The light curves of the system posses nearly sinusoidal shapes with the amplitudes of Δ m > 0.m7, what is typical for young pre-cataclysmic variables with sdO-subdwarfs and orbit inclinations of less than 45◦. The optical spectrum contains dominant radiation of the hot subdwarf with the HI and He II absorption lines and strong emission lines, which are formed in the atmosphere of the secondary owing to the reflection effects. Radial velocities of the cool star were measured by analyzing the λλ 4630-4650 Å Bowen blend, which for the first time allowed to determine the component masses. A numerical simulation of the light curves and spectra of TW Crv, obtaining a complete set of systems fundamental parameters was carried out. The hot star parameters prompt its belonging to the sdOsubdwarf class at the stage of transition to the cooling white dwarf sequence. The absence of its observable planetary nebula is caused by a long-lasting evolution of the system after the common envelope state. The secondary component has a luminosity excess, which is typical for other young sdO-subdwarf precataclysmic variables. Its position on the " age-luminosity excess" diagram points at the accuracy of the obtained set of TW Crv fundamental parameters and at the similarity of its evolutionary and physical conditions with that of other BE UMa-type objects.
Circadian control of the daily plasma glucose rhythm: an interplay of GABA and glutamate.
Kalsbeek, Andries; Foppen, Ewout; Schalij, Ingrid; Van Heijningen, Caroline; van der Vliet, Jan; Fliers, Eric; Buijs, Ruud M
2008-09-15
The mammalian biological clock, located in the hypothalamic suprachiasmatic nuclei (SCN), imposes its temporal structure on the organism via neural and endocrine outputs. To further investigate SCN control of the autonomic nervous system we focused in the present study on the daily rhythm in plasma glucose concentrations. The hypothalamic paraventricular nucleus (PVN) is an important target area of biological clock output and harbors the pre-autonomic neurons that control peripheral sympathetic and parasympathetic activity. Using local administration of GABA and glutamate receptor (ant)agonists in the PVN at different times of the light/dark-cycle we investigated whether daily changes in the activity of autonomic nervous system contribute to the control of plasma glucose and plasma insulin concentrations. Activation of neuronal activity in the PVN of non-feeding animals, either by administering a glutamatergic agonist or a GABAergic antagonist, induced hyperglycemia. The effect of the GABA-antagonist was time dependent, causing increased plasma glucose concentrations only when administered during the light period. The absence of a hyperglycemic effect of the GABA-antagonist in SCN-ablated animals provided further evidence for a daily change in GABAergic input from the SCN to the PVN. On the other hand, feeding-induced plasma glucose and insulin responses were suppressed by inhibition of PVN neuronal activity only during the dark period. These results indicate that the pre-autonomic neurons in the PVN are controlled by an interplay of inhibitory and excitatory inputs. Liver-dedicated sympathetic pre-autonomic neurons (responsible for hepatic glucose production) and pancreas-dedicated pre-autonomic parasympathetic neurons (responsible for insulin release) are controlled by inhibitory GABAergic contacts that are mainly active during the light period. Both sympathetic and parasympathetic pre-autonomic PVN neurons also receive excitatory inputs, either from the biological clock (sympathetic pre-autonomic neurons) or from non-clock areas (para-sympathetic pre-autonomic neurons), but the timing information is mainly provided by the GABAergic outputs of the biological clock.
Circadian Control of the Daily Plasma Glucose Rhythm: An Interplay of GABA and Glutamate
Kalsbeek, Andries; Foppen, Ewout; Schalij, Ingrid; Van Heijningen, Caroline; van der Vliet, Jan; Fliers, Eric; Buijs, Ruud M.
2008-01-01
The mammalian biological clock, located in the hypothalamic suprachiasmatic nuclei (SCN), imposes its temporal structure on the organism via neural and endocrine outputs. To further investigate SCN control of the autonomic nervous system we focused in the present study on the daily rhythm in plasma glucose concentrations. The hypothalamic paraventricular nucleus (PVN) is an important target area of biological clock output and harbors the pre-autonomic neurons that control peripheral sympathetic and parasympathetic activity. Using local administration of GABA and glutamate receptor (ant)agonists in the PVN at different times of the light/dark-cycle we investigated whether daily changes in the activity of autonomic nervous system contribute to the control of plasma glucose and plasma insulin concentrations. Activation of neuronal activity in the PVN of non-feeding animals, either by administering a glutamatergic agonist or a GABAergic antagonist, induced hyperglycemia. The effect of the GABA-antagonist was time dependent, causing increased plasma glucose concentrations only when administered during the light period. The absence of a hyperglycemic effect of the GABA-antagonist in SCN-ablated animals provided further evidence for a daily change in GABAergic input from the SCN to the PVN. On the other hand, feeding-induced plasma glucose and insulin responses were suppressed by inhibition of PVN neuronal activity only during the dark period. These results indicate that the pre-autonomic neurons in the PVN are controlled by an interplay of inhibitory and excitatory inputs. Liver-dedicated sympathetic pre-autonomic neurons (responsible for hepatic glucose production) and pancreas-dedicated pre-autonomic parasympathetic neurons (responsible for insulin release) are controlled by inhibitory GABAergic contacts that are mainly active during the light period. Both sympathetic and parasympathetic pre-autonomic PVN neurons also receive excitatory inputs, either from the biological clock (sympathetic pre-autonomic neurons) or from non-clock areas (para-sympathetic pre-autonomic neurons), but the timing information is mainly provided by the GABAergic outputs of the biological clock. PMID:18791643
Investigation of methods for calculating duration of lightsignal regulation cycle
NASA Astrophysics Data System (ADS)
Dorokhin, S. V.; Novikov, A. N.; Zelikov, V. A.; Strukov, Y. V.; Novikov, I. A.; Shevtsova, A. G.; Likhachev, D. V.
2018-05-01
The research objective is development of a new approach to determining of mode operation of traffic lights taking into consideration advanced characteristics of traffic flow. It will allow one to decrease transport delay significantly while a vehicle on the way and, using signal control, to increase main parameters on the whole, such as fuel consumption, travel time and traffic speed. The research shows that basic approaches, which are applied nowadays to determine main parameters of traffic lights, do not allow one to take into consideration a number of characteristics of traffic flow, so it leads to many challenges that appear as ineffective using of traffic lights. There is critical transport delay at many controlled crossroads so it can lead to emergence of traffic accidents. The research contributes to the knowledge, studying the experience of using these approaches and, on the basis of their improvement and development of new approaches, allowing one to reduce risks to a minimum. The study also provides an opportunity to expand the scope of further research in this area, combining and applying lessons learned.
Powell, Sarah R; Fuchs, Lynn S; Cirino, Paul T; Fuchs, Douglas; Compton, Donald L; Changas, Paul C
2015-07-01
The focus of the present study was enhancing word-problem and calculation achievement in ways that support pre-algebraic thinking among 2 nd -grade students at risk for mathematics difficulty. Intervention relied on a multi-tier support system (i.e., responsiveness-to-intervention or RTI) in which at-risk students participate in general classroom instruction and receive supplementary small-group tutoring. Participants were 265 students in 110 classrooms in 25 schools. Teachers were randomly assigned to 3 conditions: calculation RTI, word-problem RTI, and business-as-usual control. Intervention lasted 17 weeks. Multilevel modeling indicated that calculation RTI improved calculation but not word-problem outcomes; word-problem RTI enhanced proximal word-problem outcomes as well as performance on some calculation outcomes; and word-problem RTI provided a stronger route than calculation RTI to pre-algebraic knowledge.
Powell, Sarah R.; Fuchs, Lynn S.; Cirino, Paul T.; Fuchs, Douglas; Compton, Donald L.; Changas, Paul C.
2014-01-01
The focus of the present study was enhancing word-problem and calculation achievement in ways that support pre-algebraic thinking among 2nd-grade students at risk for mathematics difficulty. Intervention relied on a multi-tier support system (i.e., responsiveness-to-intervention or RTI) in which at-risk students participate in general classroom instruction and receive supplementary small-group tutoring. Participants were 265 students in 110 classrooms in 25 schools. Teachers were randomly assigned to 3 conditions: calculation RTI, word-problem RTI, and business-as-usual control. Intervention lasted 17 weeks. Multilevel modeling indicated that calculation RTI improved calculation but not word-problem outcomes; word-problem RTI enhanced proximal word-problem outcomes as well as performance on some calculation outcomes; and word-problem RTI provided a stronger route than calculation RTI to pre-algebraic knowledge. PMID:26097244
[NIR-SERS Spectra Detection of Cytidine on Nano-Silver Films].
Zhang, De-qing; Liu, Ren-ming; Zhang, Guo-qiang; Zhang, Yan; Xiong, Yang; Zhang, Chuan-yun; Li, Lun; Si, Min-zhen
2016-03-01
The polyvinyl alcohol (PVA) protected silver glass-like nanostructure (PVA-Ag-GNS) with high surface-enhanced Raman scattering (SERS) activity was prepared and employed to detect the near-infrared surface enhanced Raman scattering (NIR-SERS) spectra of cytidine aqueous solution (10(-2)-10(-8) mol x L(-1)). In the work, the near-infrared laser beam (785 nm) was used as the excitation light source. The experiment results show that high-quality NIR-SERS spectra were obtained in the ranges of 300 to 2 000 cm(-1) and the detection limit of cytidine aqueous solution was down to 10(-7) mol x L(-1). Meanwhile, the PVA-Ag-GNS shows a high enhancement factor (EF) of -10(8). In order to test the optical reproducibility of PVA-Ag-GNS, ten samples of cytidine aqueous solution (10(-2)-10(-5) mol x L(-1)) had been dropped onto the surface of PVA-Ag-GNS respectively. Meanwhile, these samples were measured by the portable Raman spectrometer. As a result, the PVA-Ag-GNS demonstrated good optical reproducibility in the detection of cytidine aqueous solution. In addition, to explain the reason of enhancement effect, the ultraviolet-visible (UV-Vis) extinction spectrum and scanning electron microscope (SEM) of cytidine molecules adsorbed on the surface of PVA-Ag-GNS were measured. There is plasmon resonance band at 800 nm in the UV-Vis extinction Spectrum of the compound system. Therefore, when the near-infrared laser beam (785 nm) was used as excitation light source, the compound system may produce strongly surface plasmon resonance (SPR). According to the SEM of PVA-Ag-GNS, there are much interstitial between the silver nanoparticles. So NIR-SERS is mainly attributed to electromagnetic (EM) fields associated with strong surface plasmon resonance. At last, the geometry optimization and pre-Raman spectrum of cytidine for the ground states were performed with DFT, B3LYP functional and the 6-311G basis set, and the near-infrared laser with wavelength of 785 nm was employed in the pre-Raman spectrum calculation process. The calculation results without imaginary frequency and the results match pretty well with the experimental Raman spectrum. At the same time, the assignations of Raman bands and adsorption behaviors of cytidine molecules on the surface of PVA-Ag-GNS are also discussed. According to our experiment and calculations, cytidine molecules mainly adsorbed on silver nanoparticles via the ribose moiety and amino group may get close to the local electromagnetic field.
Distance measurement based on light field geometry and ray tracing.
Chen, Yanqin; Jin, Xin; Dai, Qionghai
2017-01-09
In this paper, we propose a geometric optical model to measure the distances of object planes in a light field image. The proposed geometric optical model is composed of two sub-models based on ray tracing: object space model and image space model. The two theoretic sub-models are derived on account of on-axis point light sources. In object space model, light rays propagate into the main lens and refract inside it following the refraction theorem. In image space model, light rays exit from emission positions on the main lens and subsequently impinge on the image sensor with different imaging diameters. The relationships between imaging diameters of objects and their corresponding emission positions on the main lens are investigated through utilizing refocusing and similar triangle principle. By combining the two sub-models together and tracing light rays back to the object space, the relationships between objects' imaging diameters and corresponding distances of object planes are figured out. The performance of the proposed geometric optical model is compared with existing approaches using different configurations of hand-held plenoptic 1.0 cameras and real experiments are conducted using a preliminary imaging system. Results demonstrate that the proposed model can outperform existing approaches in terms of accuracy and exhibits good performance at general imaging range.
Light Pollution at Mount Wilson: Effect of Lighting Technology Changes
NASA Astrophysics Data System (ADS)
Garstang, R. H.
2000-05-01
In an earlier paper (Bull. AAS. 30, 838, 1998; Mem. Soc. Astr. Italia, in press, 2000) I studied the effects of population growth and of smog on the historical growth of light pollution at Mount Wilson. I have now done some very crude calculations to evaluate the effect of changes in lighting technology - the most important change being from incandescent lamps to mercury vapor lamps to high pressure sodium lamps in street lighting. I am greatly indebted to George Eslinger, lately Director of the Bureau of Public Lighting of the City of Los Angeles, for information on the numbers and types of street lights in that City. The ratio of numbers of lamps of different kinds throughout the Los Angeles basin at any given date has been assumed to be the same as in the City. The contributions to the photon output in the B and V photometric bands have been estimated. The calculations show a rate of increase of the V brightness greater than that obtained if lighting changes are neglected. The B brightness shows a maximum during the period when mercury vapor street lighting predominated. I hope to refine my calculations when additional information becomes available.
Hegaard, Hanne Kristine; Rode, Line; Katballe, Malene Kjær; Langberg, Henning; Ottesen, Bent; Damm, Peter
2017-08-01
In order to examine the association between pre-pregnancy leisure time physical activities and gestational weight gain, postpartum weight gain and birth weight, we analysed prospectively collected data from 1827 women with singleton term pregnancies. Women were categorised in groups of sedentary women, light exercisers, moderate exercisers and competitive athletes. The results showed that sedentary women on average gained 14.1 kg during pregnancy, whereas light exercisers gained 13.7 kg, moderate exercisers gained 14.3 kg and competitive athletes 16.1 kg. Competitive athletes had an increased risk of having a gestational weight gain above Institute of Medicine (IOM) recommendations with an odds ratio of 2.60 (1.32-5.15) compared to light exercisers. However, birth weight and one year postpartum weight was similar for all four groups. Thus, although competitive athletes gain more weight than recommended during pregnancy, this may not affect birth weight or postpartum weight. Impact statement What is already known on this subjectPrevious studies have found that increased pre-pregnancy physical activity is associated with lower gestational weight gain during the last trimester, but showed no association between the pre-pregnancy level of physical activity and mean birth weight. What the results of this study addWe found that women classified as competitive exercisers had a 2.6-fold increased risk of gaining more weight than recommended compared to light exercisers. Nearly 6 out of 10 women among the competitive exercisers gained more weight than recommended by IOM. Surprisingly, this did not appear to increase birth weight or post-partum weight gain, but other adverse effects cannot be excluded. What the implications are of these findings for clinical practice and/or further researchIn the clinical practice it may be relevant to focus on and advise pre-pregnancy competitive exercisers in order to prevent excessive gestational weight gain.
Korzynska, Anna; Roszkowiak, Lukasz; Pijanowska, Dorota; Kozlowski, Wojciech; Markiewicz, Tomasz
2014-01-01
The aim of this study is to compare the digital images of the tissue biopsy captured with optical microscope using bright field technique under various light conditions. The range of colour's variation in immunohistochemically stained with 3,3'-Diaminobenzidine and Haematoxylin tissue samples is immense and coming from various sources. One of them is inadequate setting of camera's white balance to microscope's light colour temperature. Although this type of error can be easily handled during the stage of image acquisition, it can be eliminated with use of colour adjustment algorithms. The examination of the dependence of colour variation from microscope's light temperature and settings of the camera is done as an introductory research to the process of automatic colour standardization. Six fields of view with empty space among the tissue samples have been selected for analysis. Each field of view has been acquired 225 times with various microscope light temperature and camera white balance settings. The fourteen randomly chosen images have been corrected and compared, with the reference image, by the following methods: Mean Square Error, Structural SIMilarity and visual assessment of viewer. For two types of backgrounds and two types of objects, the statistical image descriptors: range, median, mean and its standard deviation of chromaticity on a and b channels from CIELab colour space, and luminance L, and local colour variability for objects' specific area have been calculated. The results have been averaged for 6 images acquired in the same light conditions and camera settings for each sample. The analysis of the results leads to the following conclusions: (1) the images collected with white balance setting adjusted to light colour temperature clusters in certain area of chromatic space, (2) the process of white balance correction for images collected with white balance camera settings not matched to the light temperature moves image descriptors into proper chromatic space but simultaneously the value of luminance changes. So the process of the image unification in a sense of colour fidelity can be solved in separate introductory stage before the automatic image analysis.