Kilowatt Reactor Using Stirling TechnologY (KRUSTY) Demonstration. CEDT Phase 1 Preliminary Design Documentation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanchez, Rene Gerardo; Hutchinson, Jesson D.; Mcclure, Patrick Ray

2015-08-20

The intent of the integral experiment request IER 299 (called KiloPower by NASA) is to assemble and evaluate the operational performance of a compact reactor configuration that closely resembles the flight unit to be used by NASA to execute a deep space exploration mission. The reactor design will include heat pipes coupled to Stirling engines to demonstrate how one can generate electricity when extracting energy from a “nuclear generated” heat source. This series of experiments is a larger scale follow up to the DUFF series of experiments1,2 that were performed using the Flat-Top assembly.

30-kW class Arcjet Advanced Technology Transition Demonstration (ATTD) flight experiment diagnostic package

NASA Astrophysics Data System (ADS)

Kriebel, M. M.; Stevens, N. J.

1992-07-01

TRW, Rocket Research Co and Defense Systems Inc are developing a space qualified 30-kW class arcjet flight unit as a part of the Arcjet ATTD program. During space operation the package will measure plume deposition and contamination, electromagnetic interference, thermal radiation, arcjet thruster performance, and plume heating in order to quantify arcjet operational interactions. The Electric Propulsion Space Experiment (ESEX) diagnostic package is described. The goals of ESEX are the demonstration of a high powered arcjet performance and the measurement of potential arcjet-spacecraft interactions which cannot be determined in ground facilities. Arcjet performance, plume characterization, thermal radiation flux and the electromagnetic interference (EMI) experiment as well as experiment operations with a preliminary operations plan are presented.

The Majorana Demonstrator Status and Preliminary Results

DOE PAGES

Yu, C. -H.; Alvis, S. I.; Arnquist, I. J.; ...

2018-01-01

The MAJORANA Collaboration is using an array of high-purity Ge detectors to search for neutrinoless double-beta decay in 76Ge. Searches for neutrinoless double-beta decay are understood to be the only viable experimental method for testing the Majorana nature of the neutrino. Observation of this decay would imply violation of lepton number, that neutrinos are Majorana in nature, and provide information on the neutrino mass. The MAJORANA DEMONSTRATOR comprises 44.1 kg of p-type point-contact Ge detectors (29.7 kg enriched in 76Ge) surrounded by a low-background shield system. The experiment achieved a high efficiency of converting raw Ge material to detectors andmore » an unprecedented detector energy resolution of 2.5 keV FWHM at Q ββ. The MAJORANA collaboration began taking physics data in 2016. Here, this paper summarizes key construction aspects of the Demonstrator and shows preliminary results from initial data.« less

The Majorana Demonstrator Status and Preliminary Results

NASA Astrophysics Data System (ADS)

Yu, C.-H.; Alvis, S. I.; Arnquist, I. J.; Avignone, F. T.; Barabash, A. S.; Barton, C. J.; Bertrand, F. E.; Bode, T.; Brudanin, V.; Busch, M.; Buuck, M.; Caldwell, T. S.; Chan, Y.-D.; Christofferson, C. D.; Chu, P.-H.; Cuesta, C.; Detwiler, J. A.; Dunagan, C.; Efremenko, Yu; Ejiri, H.; Elliott, S. R.; Gilliss, T.; Giovanetti, G. K.; Green, M.; Gruszko, J.; Guinn, I. S.; Guiseppe, V. E.; Haufe, C. R.; Hehn, L.; Henning, R.; Hoppe, E. W.; Howe, M. A.; Keeter, K. J.; Kidd, M. F.; Konovalov, S. I.; Kouzes, R. T.; Lopez, A. M.; Martin, R. D.; Massarczyk, R.; Meijer, S. J.; Mertens, S.; Myslik, J.; Othman, G.; Pettus, W.; Poon, A. W. P.; Radford, D. C.; Rager, J.; Reine, A. L.; Rielage, K.; Ruof, N. W.; Shanks, B.; Shirchenko, M.; Suriano, A. M.; Tedeschi, D.; Varner, R. L.; Vasilyev, S.; Vetter, K.; Vorren, K.; White, B. R.; Wilkerson, J. F.; Wiseman, C.; Xu, W.; Yakushev, E.; Yumatov, V.; Zhitnikov, I.; Zhu, B. Z.

2018-05-01

The MAJORANA Collaboration is using an array of high-purity Ge detectors to search for neutrinoless double-beta decay in 76Ge. Searches for neutrinoless double-beta decay are understood to be the only viable experimental method for testing the Majorana nature of the neutrino. Observation of this decay would imply violation of lepton number, that neutrinos are Majorana in nature, and provide information on the neutrino mass. The MAJORANA DEMONSTRATOR comprises 44.1 kg of p-type point-contact Ge detectors (29.7 kg enriched in 76Ge) surrounded by a low-background shield system. The experiment achieved a high efficiency of converting raw Ge material to detectors and an unprecedented detector energy resolution of 2.5 keV FWHM at Qββ. The MAJORANA collaboration began taking physics data in 2016. This paper summarizes key construction aspects of the Demonstrator and shows preliminary results from initial data.

The Majorana Demonstrator Status and Preliminary Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yu, C. -H.; Alvis, S. I.; Arnquist, I. J.

The MAJORANA Collaboration is using an array of high-purity Ge detectors to search for neutrinoless double-beta decay in 76Ge. Searches for neutrinoless double-beta decay are understood to be the only viable experimental method for testing the Majorana nature of the neutrino. Observation of this decay would imply violation of lepton number, that neutrinos are Majorana in nature, and provide information on the neutrino mass. The MAJORANA DEMONSTRATOR comprises 44.1 kg of p-type point-contact Ge detectors (29.7 kg enriched in 76Ge) surrounded by a low-background shield system. The experiment achieved a high efficiency of converting raw Ge material to detectors andmore » an unprecedented detector energy resolution of 2.5 keV FWHM at Q ββ. The MAJORANA collaboration began taking physics data in 2016. Here, this paper summarizes key construction aspects of the Demonstrator and shows preliminary results from initial data.« less

Preliminary disposal limits, plume interaction factors, and final disposal limits

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flach, G.

In the 2008 E-Area Performance Assessment (PA), each final disposal limit was constructed as the product of a preliminary disposal limit and a plume interaction factor. The following mathematical development demonstrates that performance objectives are generally expected to be satisfied with high confidence under practical PA scenarios using this method. However, radionuclides that experience significant decay between a disposal unit and the 100-meter boundary, such as H-3 and Sr-90, can challenge performance objectives, depending on the disposed-of waste composition, facility geometry, and the significance of the plume interaction factor. Pros and cons of analyzing single disposal units or multiple disposalmore » units as a group in the preliminary disposal limits analysis are also identified.« less

Correlation mapping for visualizing propagation of pulsatile CSF motion in intracranial space based on magnetic resonance phase contrast velocity images: preliminary results.

PubMed

Yatsushiro, Satoshi; Hirayama, Akihiro; Matsumae, Mitsunori; Kajiwara, Nao; Abdullah, Afnizanfaizal; Kuroda, Kagayaki

2014-01-01

Correlation time mapping based on magnetic resonance (MR) velocimetry has been applied to pulsatile cerebrospinal fluid (CSF) motion to visualize the pressure transmission between CSF at different locations and/or between CSF and arterial blood flow. Healthy volunteer experiments demonstrated that the technique exhibited transmitting pulsatile CSF motion from CSF space in the vicinity of blood vessels with short delay and relatively high correlation coefficients. Patient and healthy volunteer experiments indicated that the properties of CSF motion were different from the healthy volunteers. Resultant images in healthy volunteers implied that there were slight individual difference in the CSF driving source locations. Clinical interpretation for these preliminary results is required to apply the present technique for classifying status of hydrocephalus.

Full-scale Transport Controlled Impact Demonstration Program

NASA Technical Reports Server (NTRS)

1987-01-01

The Federal Aviation Administration (FAA) and NASA conducted a full-scale air-to-surface impact-survivable impact demonstration with a remotely piloted transport aircraft on 1 December 1984, at Edwards Air Force Base, California. The test article consisted of experiments, special equipment, and supporting systems, such as antimisting kerosene (AMK), crashworthiness structural/restraint, analytical modeling, cabin fire safety, flight data recorders, post-impact investigation, instrumentation/data acquisition systems, remotely piloted vehicle/flight control systems, range and flight safety provisions, etc. This report describes the aircraft, experiments, systems, activities, and events which lead up to the Controlled Impact Demonstration (CID). An overview of the final unmanned remote control flight and sequence of impact events are delineated. Preliminary post CID observations are presented.

Creating Micro-Videos to Demonstrate Technology Learning

ERIC Educational Resources Information Center

Frydenberg, Mark; Andone, Diana

2016-01-01

Short videos, also known as micro-videos, have emerged as a platform for sharing ideas, experiences, and life events on online social networks. This paper shares preliminary results of a study involving students from two universities who created six-second videos using the Vine mobile app to explain or illustrate technology concepts. An analysis…

The Windy Island Soliton Experiment (WISE): Shallow Water and Basin Experiment Configuration and Preliminary Observations

DTIC Science & Technology

2009-02-19

Virginia 22203-1995 The Windy Island Soliton Experiment (WISE): Shallow Water and Basin Experiment Configuration and Preliminary Observations...case letters) The Windy Island Soliton Experiment (WISE): Shallow water and Basin Experiment Configuration and Preliminary Observations 5. FUNDING...release; distribution is unlimited 12b. DISTRIBUTION CODE 13. ABSTRACT (maximum 200 words) The Windy Islands Soliton Experiment (WISE) was

ATS-6 - Technical aspects of the Health/Education Telecommunications Experiment

NASA Technical Reports Server (NTRS)

Boor, J. L.; Braunstein, J.; Janky, J. M.; Ogden, D.; Potter, J. G.; Harper, E. L.; Volkmer, E.; Whalen, A. A.; Henderson, E.; Hupe, H. H.

1975-01-01

An overview is given of the HET experiment on ATS-6. The paper is divided into nine parts, including a technical overview, a preliminary evaluation of the HET demonstration, a review of operations at the Denver uplink terminal, a discussion of remote ground terminals, a review of C-band comprehensive terminals and of S-band comprehensive terminals, and parts devoted to general network operations, technical management and effectiveness of the network, and the site equipment operator.

A High-Energy Technology Demonstration Platfom: The First Step in a Stepping Stones Approach to Energy-Rich Space Infrastructures

NASA Technical Reports Server (NTRS)

Carrington, Connie; Day, Greg

2004-01-01

The sun provides an abundant source of energy in space, which can be used to power exploration vehicles and infrastructures that support exploration. A first step in developing and demonstrating the necessary technologies to support solar-powered exploration could be a 100-kWe-class solar-powered platform in Earth orbit. This platform would utilize advanced technologies in solar power collection and generation, power management and distribution, thermal management, and electric propulsion. It would also provide a power-rich free-flying platform to demonstrate in space a portfolio of technology flight experiments. This paper presents a preliminary design concept for a 100-kWe solar-powered satellite with the capability to use high-powered electric propulsion, and to flight-demonstrate a variety of payload experiments.

Imaging and sensing based on dual-pulse nonlinear photoacoustic contrast: a preliminary study on fatty liver

NASA Astrophysics Data System (ADS)

Tian, Chao; Xie, Zhixing; Fabiilli, Mario; Wang, Xueding

2015-03-01

We developed a simple and effective contrast for tissue characterization based on the recently proposed dual-pulse nonlinear photoacoustic technology. The new contrast takes advantage of the temperature dependence of Grüneisen parameter of tissue and involves a dual-pulse laser excitation process. A short pulse first heats the sample and causes a temperature jump, which then leads to the change of Grüneisen parameter and amplitude of the photoacoustic signal of the second pulse. For different tissues, the induced rate or trend of change is expected to be different, which constitutes the basis of the new contrast. Preliminary phantom experiment in blood and lipid mixtures and in vitro experiment in fatty rat liver have demonstrated that the proposed contrast has the capability of fast characterization of lipid-rich and blood-rich tissues.

Extrapolating Accelerated UV Weathering Data: Perspective From PVQAT Task Group 5 (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, D.; Annigoni, E.; Ballion, A.

2015-02-01

Taskgroup 5 (TG5) is concerned with a accelerated aging standard incorporating factors including ultraviolet radiation, temperature, and moisture. Separate experiments are being conducted in support of a test standard via the regional sub-groups in Asia, Europe, and the United States. The authors will describe the objectives and timeline for the TG5 interlaboratory study being directed out of the USA. Qualitative preliminary data from the experiment is presented. To date, the encapsulation transmittance experiment has: replicated behaviors of fielded materials (including specimen location- and formulation additive-specific discoloration); demonstrated coupling between UV aging and temperature; demonstrated that degradation in EVA results frommore » UV- aging; and obtained good qualitative comparison between Xe and UVA-340 sources for EVA. To date, the encapsulation adhesion experiment (using the compressive shear test to quantify strength of attachment) has demonstrated that attachment strength can decrease drastically (>50%) with age; however, early results suggest significant factor (UV, T, RH) dependence. Much remains to be learned about adhesion.« less

Preliminary experiments on pharmacokinetic diffuse fluorescence tomography of CT-scanning mode

NASA Astrophysics Data System (ADS)

Zhang, Yanqi; Wang, Xin; Yin, Guoyan; Li, Jiao; Zhou, Zhongxing; Zhao, Huijuan; Gao, Feng; Zhang, Limin

2016-10-01

In vivo tomographic imaging of the fluorescence pharmacokinetic parameters in tissues can provide additional specific and quantitative physiological and pathological information to that of fluorescence concentration. This modality normally requires a highly-sensitive diffuse fluorescence tomography (DFT) working in dynamic way to finally extract the pharmacokinetic parameters from the measured pharmacokinetics-associated temporally-varying boundary intensity. This paper is devoted to preliminary experimental validation of our proposed direct reconstruction scheme of instantaneous sampling based pharmacokinetic-DFT: A highly-sensitive DFT system of CT-scanning mode working with parallel four photomultiplier-tube photon-counting channels is developed to generate an instantaneous sampling dataset; A direct reconstruction scheme then extracts images of the pharmacokinetic parameters using the adaptive-EKF strategy. We design a dynamic phantom that can simulate the agent metabolism in living tissue. The results of the dynamic phantom experiments verify the validity of the experiment system and reconstruction algorithms, and demonstrate that system provides good resolution, high sensitivity and quantitativeness at different pump speed.

Creating Micro-Videos to Demonstrate Technology Learning and Digital Literacy

ERIC Educational Resources Information Center

Frydenberg, Mark; Andone, Diana

2016-01-01

Purpose: Short videos, also known as micro-videos, have emerged as a platform for sharing ideas, experiences and life events via online social networks. This paper aims to share preliminary results of a study, involving students from two universities who created six-second videos using the Vine mobile app to explain or illustrate technological…

Preliminary plan for a Shuttle Coherent Atmospheric Lidar Experiment (SCALE)

NASA Technical Reports Server (NTRS)

Fitzjarrald, D.; Beranek, R.; Bilbro, J.; Mabry, J.

1985-01-01

A study has been completed to define a Shuttle experiment that solves the most crucial scientific and engineering problems involved in building a satellite Doppler wind profiler for making global wind measurements. The study includes: (1) a laser study to determine the feasibility of using the existing NOAA Windvan laser in the Space Shuttle spacecraft; (2) a preliminary optics and telescope design; (3) an accommodations study including power, weight, thermal, and control system requirements; and (4) a flight trajectory and operations plan designed to accomplish the required scientific and engineering goals. The experiment will provide much-needed data on the global distribution of atmospheric aerosols and demonstrate the technique of making wind measurements from space, including scanning the laser beam and interpreting the data. Engineering accomplishments will include space qualification of the laser, development of signal processing and lag angle compensation hardware and software, and telescope and optics design. All of the results of this limited Spacelab experiment will be directly applicable to a complete satellite wind profiler for the Earth Observation System/Space Station or other free-flying satellite.

AIC Computations Using Navier-Stokes Equations on Single Image Supercomputers For Design Optimization

NASA Technical Reports Server (NTRS)

Guruswamy, Guru

2004-01-01

A procedure to accurately generate AIC using the Navier-Stokes solver including grid deformation is presented. Preliminary results show good comparisons between experiment and computed flutter boundaries for a rectangular wing. A full wing body configuration of an orbital space plane is selected for demonstration on a large number of processors. In the final paper the AIC of full wing body configuration will be computed. The scalability of the procedure on supercomputer will be demonstrated.

Spread spectrum time-resolved diffuse optical measurement system for enhanced sensitivity in detecting human brain activity

NASA Astrophysics Data System (ADS)

Mehta, Kalpesh; Hasnain, Ali; Zhou, Xiaowei; Luo, Jianwen; Penney, Trevor B.; Chen, Nanguang

2017-04-01

Diffuse optical spectroscopy (DOS) and imaging methods have been widely applied to noninvasive detection of brain activity. We have designed and implemented a low cost, portable, real-time one-channel time-resolved DOS system for neuroscience studies. Phantom experiments were carried out to test the performance of the system. We further conducted preliminary human experiments and demonstrated that enhanced sensitivity in detecting neural activity in the cortex could be achieved by the use of late arriving photons.

Daily Life Experience and Somatic Symptoms: A Preliminary Report.

DTIC Science & Technology

1981-03-01

AAO7 9 859 STATE UNIV OF NEW YORK AT STONY BROOK FG 5/10 DAILY LIFE EXPERIENCE AND SOMATIC SYMPTOMS: A PRELIMINARY REPOR--ETC(U) MAR 8I A A STONE. J...Experience and Somatic Symptoms: A Preliminary Report Arthur A. Stone Long Island Research Institute and Department of Psychiatry arnd Behavioral...TITLE (and S..,til.) s. ALF - , rlA9OQ COVERED Daily Life Experience and Somatic Symptoms: A Technical p " Preliminary Report, EL..... S. PERFORMING

Trajectory-Oriented Approach to Managing Traffic Complexity: Trajectory Flexibility Metrics and Algorithms and Preliminary Complexity Impact Assessment

NASA Technical Reports Server (NTRS)

Idris, Husni; Vivona, Robert A.; Al-Wakil, Tarek

2009-01-01

This document describes exploratory research on a distributed, trajectory oriented approach for traffic complexity management. The approach is to manage traffic complexity based on preserving trajectory flexibility and minimizing constraints. In particular, the document presents metrics for trajectory flexibility; a method for estimating these metrics based on discrete time and degree of freedom assumptions; a planning algorithm using these metrics to preserve flexibility; and preliminary experiments testing the impact of preserving trajectory flexibility on traffic complexity. The document also describes an early demonstration capability of the trajectory flexibility preservation function in the NASA Autonomous Operations Planner (AOP) platform.

High-frame-rate digital radiographic videography

NASA Astrophysics Data System (ADS)

King, Nicholas S. P.; Cverna, Frank H.; Albright, Kevin L.; Jaramillo, Steven A.; Yates, George J.; McDonald, Thomas E.; Flynn, Michael J.; Tashman, Scott

1994-10-01

High speed x-ray imaging can be an important tool for observing internal processes in a wide range of applications. In this paper we describe preliminary implementation of a system having the eventual goal of observing the internal dynamics of bone and joint reactions during loading. Two Los Alamos National Laboratory (LANL) gated and image intensified camera systems were used to record images from an x-ray image convertor tube to demonstrate the potential of high frame-rate digital radiographic videography in the analysis of bone and joint dynamics of the human body. Preliminary experiments were done at LANL to test the systems. Initial high frame-rate imaging (from 500 to 1000 frames/s) of a swinging pendulum mounted to the face of an X-ray image convertor tube demonstrated high contrast response and baseline sensitivity. The systems were then evaluated at the Motion Analysis Laboratory of Henry Ford Health Systems Bone and Joint Center. Imaging of a 9 inch acrylic disk with embedded lead markers rotating at approximately 1000 RPM, demonstrated the system response to a high velocity/high contrast target. By gating the P-20 phosphor image from the X-ray image convertor with a second image intensifier (II) and using a 100 microsecond wide optical gate through the second II, enough prompt light decay from the x-ray image convertor phosphor had taken place to achieve reduction of most of the motion blurring. Measurement of the marker velocity was made by using video frames acquired at 500 frames/s. The data obtained from both experiments successfully demonstrated the feasibility of the technique. Several key areas for improvement are discussed along with salient test results and experiment details.

STS-74/MIR Photogrammetric Appendage Structural Dynamics Experiment Preliminary Data Analysis

NASA Technical Reports Server (NTRS)

Gilbert, Michael G.; Welch, Sharon S.; Pappa, Richard S.; Demeo, Martha E.

1997-01-01

The Photogrammetric Appendage Structural Dynamics Experiment was designed, developed, and flown to demonstrate and prove measurement of the structural vibration response of a Russian Space Station Mir solar array using photogrammetric methods. The experiment flew on the STS-74 Space Shuttle mission to Mir in November 1995 and obtained video imagery of solar array structural response to various excitation events. The video imagery has been digitized and triangulated to obtain response time history data at discrete points on the solar array. This data has been further processed using the Eigensystem Realization Algorithm modal identification technique to determine the natural vibration frequencies, damping, and mode shapes of the solar array. The results demonstrate that photogrammetric measurement of articulating, nonoptically targeted, flexible solar arrays and appendages is a viable, low-cost measurement option for the International Space Station.

Development of polyphenylquinoxaline graphite composites

NASA Technical Reports Server (NTRS)

Hoggatt, J. T.; Hergenrother, P. M.; Shdo, J. G.

1973-01-01

The potential of polyphenylquinoxaline (PPQ)/graphite composites to serve as structural material at 316 C (600 F)has been demonstrated using a block copolymer, BlCo(13), PPQ derivative. Initially, thirteen polyphenylquinoxalines were evaluated. From this work, four candidate polymers were selected for preliminary evaluation as matrices for HMS graphite fiber reinforced composites. The preliminary composite evaluation enabled selection of one of the four polymers for advanced composite preparation and testing. Using an experimentally established cure schedule for each of the four polymers, preliminary laminates of 50% resin volume content, prepared without postcure, were tested for flexure strength and modulus, interlaminar shear strength (short beam), and tensile strength and modulus at ambient temperature. A block copolymer (Bl Co 13) derived from one mole p-bis (phenylglyoxalyl) benzene, one fourth mole 3,3'-diaminobenzidine and three-fourths mole 3,3', 4,4'-tetraminobenzophenone was selected for extensive study. Tensile, flexural, and interlaminar shear values were obtained after aging and testing postcured BlCo(13) laminates at 316 C (600 F). The potential of PPQ/graphite laminates to serve as short term structural materials at temperatures up to 371 C (700 F) was demonstrated through weight loss experiments.

Noninvasive Ultrasound Transdermal Insulin Delivery and Glucose Monitoring Using a Low-Profile Cymbal Array

NASA Astrophysics Data System (ADS)

Park, E.-J.; Luis, J.; Meyer, R. J.; Pishko, M. V.; Smith, N. B.

2006-05-01

Recent studies have shown that ultrasound mediated transdermal drug delivery offers promising results for noninvasive drug administration. The purpose of this study was to demonstrate ultrasonic transdermal insulin delivery and in vivo sensing glucose with a novel, low-profile ultrasound array based on the cymbal transducer. As a practical device, the array composed of circular cymbal transducers was thin (< 7mm) and weighed less than 22g. Using this array on hyperglycemic rats, our previous experiments demonstrated that blood glucose would decrease by 296.7 mg/dL from 60 minutes of ultrasound exposure. With a similar intensity, our goal was to evaluate the feasibility of insulin delivery with large animals (rabbits and pigs) and noninvasively determine the glucose level of hyperglycemic rats with the array system. Ultrasound was exposed for 60 minutes at Isptp=100 mW/cm2. With the same procedure, a preliminary experiment of large animal was performed on a pig (12 kg) at Isptp=50 mW/cm2. For the control experiments in insulin delivery, the blood glucose level varied little from the initial baseline. However, for the ultrasound and insulin exposure experiment, the glucose level was found to decrease by 132.6 mg/dL in 60 minutes and continued to decrease by 208.1 mg/dL in 90 minutes. From the preliminary pig experiment, the blood glucose level decreased by 120 mg/dL in 90 minutes. To noninvasively determine the glucose level, ultrasound exposure experiments with an electrochemical glucose biosensor were performed on hyperglycemic rats. After 20 minutes ultrasound exposure, the biosensor was placed at the exposure area to determine the concentration of glucose diffused through the skin. The glucose level of rats determined by the biosensor was 408 mg/dL which was very similar to the results of conventional glucose meter reading 396.7 mg/dL. Recently, a rectangular cymbal transducer was developed to obtain a larger sonication area without an increase in array size. Preliminary experiments were performed on hyperglycemic rabbits to evaluate the new transducer design. The results showed that the rectangular array has enhanced performance compared to the circular array. All results of ultrasound application indicate the feasibility of using a low-cost, light-weight cymbal array for enhanced noninvasive transdermal insulin delivery and glucose monitoring.

Advances in Electrically Driven Thermal Management

NASA Technical Reports Server (NTRS)

Didion, Jeffrey R.

2017-01-01

Electrically Driven Thermal Management is a vibrant technology development initiative incorporating ISS based technology demonstrations, development of innovative fluid management techniques and fundamental research efforts. The program emphasizes high temperature high heat flux thermal management required for future generations of RF electronics and power electronic devices. This presentation reviews i.) preliminary results from the Electrohydrodynamic (EHD) Long Term Flight Demonstration launched on STP-H5 payload in February 2017 ii.) advances in liquid phase flow distribution control iii.) development of the Electrically Driven Liquid Film Boiling Experiment under the NASA Microgravity Fluid Physics Program.

Science Support Room Operations During Desert RATS 2009

NASA Technical Reports Server (NTRS)

Lofgren, G. E.; Horz, F.; Bell, M. S.; Cohen, B. A.; Eppler,D. B.; Evans, C. a.; Hodges, K. V.; Hynek, B. M.; Gruener, J. E.; Kring, D. A.;

MSFC integrated experiments preliminary report. [for the Skylab program

NASA Technical Reports Server (NTRS)

1974-01-01

Skylab experiments are described and their preliminary results are reported. The types of experiments described include medical, earth resources, space physics, space manufacturing, and spacecraft design.

A general model-based design of experiments approach to achieve practical identifiability of pharmacokinetic and pharmacodynamic models.

PubMed

Galvanin, Federico; Ballan, Carlo C; Barolo, Massimiliano; Bezzo, Fabrizio

2013-08-01

The use of pharmacokinetic (PK) and pharmacodynamic (PD) models is a common and widespread practice in the preliminary stages of drug development. However, PK-PD models may be affected by structural identifiability issues intrinsically related to their mathematical formulation. A preliminary structural identifiability analysis is usually carried out to check if the set of model parameters can be uniquely determined from experimental observations under the ideal assumptions of noise-free data and no model uncertainty. However, even for structurally identifiable models, real-life experimental conditions and model uncertainty may strongly affect the practical possibility to estimate the model parameters in a statistically sound way. A systematic procedure coupling the numerical assessment of structural identifiability with advanced model-based design of experiments formulations is presented in this paper. The objective is to propose a general approach to design experiments in an optimal way, detecting a proper set of experimental settings that ensure the practical identifiability of PK-PD models. Two simulated case studies based on in vitro bacterial growth and killing models are presented to demonstrate the applicability and generality of the methodology to tackle model identifiability issues effectively, through the design of feasible and highly informative experiments.

Analyses of space environment effects on active fiber optic links orbited aboard the LDEF

NASA Technical Reports Server (NTRS)

Taylor, Edward W.; Monarski, T. W.; Berry, J. N.; Sanchez, A. D.; Padden, R. J.; Chapman, S. P.

1993-01-01

The results of the 'Preliminary Analysis of WL Experiment no. 701, Space Environment Effects on Operating Fiber Optic Systems,' is correlated with space simulated post retrieval terrestrial studies performed on the M0004 experiment. Temperature cycling measurements were performed on the active optical data links for the purpose of assessing link signal to noise ratio and bit error rate performance some 69 months following the experiment deployment in low Earth orbit. The early results indicate a high correlation between pre-orbit, orbit, and post-orbit functionality of the first known and longest space demonstration of operating fiber optic systems.

Preliminary results of the scientific experiments on the Kosmos-936 biosatellite

NASA Technical Reports Server (NTRS)

1977-01-01

The scientific equipment and experiments on the Kosmos-936 biosatellite are described, including various ground controls and the lab unit for studies at the descent vehicle landing site. Preliminary results are presented of the physiological experiment with rats, biological experiments with drosophila and higher and lower plants, and radiation physics and radiobiology studies for the planning of biological protection on future space flights. The most significant conclusion from the preliminary data is that rats tolerate space flight better with an artificial force of gravity.

Review of operational aspects of initial experiments utilizing the U.S. MLS. [microwave landing system effectiveness

NASA Technical Reports Server (NTRS)

Walsh, T. M.; Morello, S. A.; Reeder, J. P.

1976-01-01

An exercise to support the Federal Aviation Administration in demonstrating the U.S. candidate for an international microwave landing system (MLS) was conducted by NASA. During this demonstration the MLS was utilized to provide the TCV Boeing 737 research airplane with guidance for automatic control during transition from conventional RNAV to MLS RNAV in curved, descending flight; flare; touchdown; and roll-out. Flight profiles, system configuration, displays, and operating procedures used in the demonstration are described, and preliminary results of flight data analysis are discussed. Recent experiences with manually controlled flight in the NAFEC MLS environment are also discussed. The demonstration shows that in automatic three-dimensional flight, the volumetric signal coverage of the MLS can be exploited to enable a commercial carrier class airplane to perform complex curved, descending paths with precision turns into short final approaches terminating in landing and roll-out, even when subjected to strong and gusty tail and cross wind components and severe wind shear.

Preliminary experiments on phase conjugation for flow visualization. [barium titanate single crystals

NASA Technical Reports Server (NTRS)

Weimer, D.; Howes, W. L.

1984-01-01

Barium titanate single crystals are discussed in the context of: the procedure for polarizing a crystal; a test for phase conjugation; transients in the production of phase conjugation; real time readout by a separate laser of a hologram induced within the crystal, including conjugation response times to on-off switching of each beam; and a demonstration of a Twyman-Green interferometer utilizing phase conjugation.

Bistatic radar sea state monitoring

NASA Technical Reports Server (NTRS)

Ruck, G. T.; Barrick, D. E.; Kaliszewski, T.

1972-01-01

Bistatic radar techniques were examined for remote measurement of the two-dimensional surface wave height spectrum of the ocean. One technique operates at high frequencies (HF), 3-30 MHz, and the other at ultrahigh frequencies (UHF), approximately 1 GHz. Only a preliminary theoretical examination of the UHF technique was performed; however the principle underlying the HF technique was demonstrated experimentally with results indicating that an HF bistatic system using a surface transmitter and an orbital receiver would be capable of measuring the two-dimensional wave height spectrum in the vicinity of the transmitter. An HF bistatic system could also be used with an airborne receiver for ground truth ocean wave spectrum measurements. Preliminary system requirements and hardware configurations are discussed for both an orbital system and an aircraft verification experiment.

Illustrating idiographic methods for translation research: moderation effects, natural clinical experiments, and complex treatment-by-subgroup interactions.

PubMed

Ridenour, Ty A; Wittenborn, Andrea K; Raiff, Bethany R; Benedict, Neal; Kane-Gill, Sandra

2016-03-01

A critical juncture in translation research involves the preliminary studies of intervention tools, provider training programs, policies, and other mechanisms used to leverage knowledge garnered at one translation stage into another stage. Potentially useful for such studies are rigorous techniques for conducting within-subject clinical trials, which have advanced incrementally over the last decade. However, these methods have largely not been utilized within prevention or translation contexts. The purpose of this manuscript is to demonstrate the flexibility, wide applicability, and rigor of idiographic clinical trials for preliminary testing of intervention mechanisms. Specifically demonstrated are novel uses of state-space modeling for testing intervention mechanisms of short-term outcomes, identifying heterogeneity in and moderation of within-person treatment mechanisms, a horizontal line plot to refine sampling design during the course of a clinic-based experimental study, and the need to test a treatment's efficacy as treatment is administered along with (e.g., traditional 12-month outcomes).

Preliminary maintenance experience for DSS 13 unattended operations demonstration. [Deep Space Network

NASA Technical Reports Server (NTRS)

Remer, D. S.; Lorden, G.

1979-01-01

The maintenance data base collected for 15 weeks of recent unattended and automated operation of DSS 13 is summarized. During this period, DSS 13 was receiving spacecraft telemetry while being controlled remotely from JPL in Pasadena. Corrective and preventive maintenance manhours are reported by subsystem for DSS 13 including the equipment added for the automation demonstration. The corrective and preventive maintenance weekly manhours at DSS 13 averaged 22 and 40, respectively. The antenna hydraulic and electronic systems accounted for about half of the preventive and corrective maintenance manhours for a comparable attended DSN station, DSS 11.

Overview of the Preliminary Design of the Optical Communication Demonstration and High-Rate Link Facility

NASA Technical Reports Server (NTRS)

Sandusky, John V.; Jeganathan, M.; Ortiz, G.; Biswas, A.; Lee, S.; Parker, G.; Liu, B.; Johnson, D.; DePew, J.; Lesh, J. R.

2000-01-01

Tlis paper presents an overview of the preliminary design of both the flight and ground systems of the Optical Communication Demonstration and High-Rate Link Facility which will demonstrate optical communication from the International Space Station to ground after its deployment in October 2002. The overview of the preliminary design of the Flight System proceeds by contrasting it with the design of the laboratory-model unit, emphasizing key changes and the rationale behind the design choices. After presenting the preliminary design of the Ground System, the timetable for the construction and deployment of the flight and ground systems is outlined.

The development of intonation in young children with cochlear implants: A preliminary study of the influence of age at implantation and length of implant experience

PubMed Central

Snow, David; Ertmer, David

2010-01-01

This study describes the development of emerging intonation in six children who had received a cochlear implant (CI) before the age of three years. At the time their implant was activated, the children ranged in age from 11 to 37 months. Spontaneous longitudinal speech samples were recorded from 30-minute sessions in which the child interacted with his or her mother. Data were collected 2 months before activation of each child's CI and at monthly intervals after activation for 6 months. The findings were compared to the typical pattern of early intonation development in children with normal hearing (NH). The results suggested that young CI recipients progress through stages similar to those observed in children with NH. However, the intonation development of children with a CI reflects a marked interaction between chronological age at implantation and amount of CI experience. That is, after 2 months of CI-assisted hearing experience, the older children demonstrated a later stage of intonation development than younger children. These preliminary results support the idea that children acquire some foundations or prerequisites of intonation production through maturation, as measured by chronological age, even without robust auditory experience. PMID:20882119

The Role of Epithelial-Mesenchymal Transition in the Formation of Normal and Neoplastic Mammary Epithelial Stem Cells

DTIC Science & Technology

2011-09-01

separating stem cell and non- stem cell populations of normal and breast cancer cells and identified EMT transcription factors most likely involved in... stem cell biology. Preliminary results directly demonstrate that transient induction of EMT increases the number of mammary epithelial stem cells...EMT and entrance into a stem - cell state. The outcome of these experiments holds important implications for the mechanisms controlling the formation of

High-power free-electron maser with frequency multiplication operating in a shortwave part of the millimeter wave range

NASA Astrophysics Data System (ADS)

Bandurkin, I. V.; Kaminsky, A. K.; Perelstein, E. A.; Peskov, N. Yu.; Savilov, A. V.; Sedykh, S. N.

2012-08-01

The possibility of using frequency multiplication in order to obtain high-power short-wavelength radiation from a free-electron maser (FEM) with a Bragg resonator has been studied. Preliminary experiments with an LIU-3000 (JINR) linear induction accelerator demonstrate the operation of a frequency-multiplying FEM at megawatt power in the 6- and 4-mm wave bands on the second and third harmonic, respectively.

CROSS-SHORE TRANSPORT OF BIMODAL SANDS.

USGS Publications Warehouse

Richmond, Bruce M.; Sallenger,, Asbury H.; Edge, Billy L.

1985-01-01

Foreshore sediment level and sediment size were monitored as part of an extensive nearshore processes experiment - DUCK 82. Changes in foreshore texture were compared with computed values of onshore transported material based on current measurements from the surf zone and sediment transport theory. Preliminary results indicate reasonable agreement between predicted size of sediment transported onshore and beach texture changes. It is also demonstrated that coarse sediment may move onshore while finer material may simultaneously move offshore. Refs.

Derivation of particulate directional information from analysis of elliptical impact craters on LDEF

NASA Technical Reports Server (NTRS)

Newman, P. J.; Mackay, N.; Deshpande, S. P.; Green, S. F.; Mcdonnell, J. A. M.

1993-01-01

The Long Duration Exposure Facility provided a gravity gradient stabilized platform which allowed limited directional information to be derived from particle impact experiments. The morphology of impact craters on semi-infinite materials contains information which may be used to determine the direction of impact much more accurately. We demonstrate the applicability of this technique and present preliminary results of measurements from LDEF and modelling of interplanetary dust and space debris.

Kinetics and pathogenesis of intracellular magnetic nanoparticle cytotoxicity

NASA Astrophysics Data System (ADS)

Giustini, Andrew J.; Gottesman, Rachel E.; Petryk, A. A.; Rauwerdink, A. M.; Hoopes, P. Jack

2011-03-01

Magnetic nanoparticles excited by alternating magnetic fields (AMF) have demonstrated effective tumor-specific hyperthermia. This treatment is effective as a monotherapy as well as a therapeutic adjuvant to chemotherapy and radiation. Iron oxide nanoparticles have been shown, so far, to be non-toxic, as are the exciting AMF fields when used at moderate levels. Although higher levels of AMF can be more effective, depending on the type of iron oxide nanoparticles use, these higher field strengths and/or frequencies can induce normal tissue heating and toxicity. Thus, the use of nanoparticles exhibiting significant heating at low AMF strengths and frequencies is desirable. Our preliminary experiments have shown that the aggregation of magnetic nanoparticles within tumor cells improves their heating effect and cytotoxicity per nanoparticle. We have used transmission electron microscopy to track the endocytosis of nanoparticles into tumor cells (both breast adenocarcinoma (MTG-B) and acute monocytic leukemia (THP-1) cells). Our preliminary results suggest that nanoparticles internalized into tumor cells demonstrate greater cytotoxicity when excited with AMF than an equivalent heat dose from excited external nanoparticles or cells exposed to a hot water bath. We have also demonstrated that this increase in SAR caused by aggregation improves the cytotoxicity of nanoparticle hyperthermia therapy in vitro.

^4He experiments near T_λ with a heat current and reduced gravity in a low-gravity simulator

NASA Astrophysics Data System (ADS)

Liu, Yuanming; Larson, Melora; Israelsson, Ulf

1998-03-01

Conventional ground-based helium experiments experience limitations due to a variation of the superfluid transition temperature (T_λ) caused by the gravity-induced hydrostatic pressure in a ^4He sample cell. A low-gravity simulator consisting a high field superconducting magnet has been built in our laboratory and the preliminary measurements demonstrated a reduction of gravity in the sample cell. (Melora Larson, Feng-Chuan Liu, and Ulf Israelsson, Czech. J. of Phys. 46, 179 (1996).) We report our latest improvements on the simulator and measurements with a new sample cell which had copper end plates, Vepsel sidewalls, and sidewall probes. The measurements showed that gravity can be canceled with a field-field gradient product of 20.7 T^2/cm (or B=15.5 Tesla), in excellent agreement with the theoretical prediction. The measurements also revealed that the boundary resistance between the thermometers and liquid helium increased from 1.6 cm^2 K/W at zero field to 2.0 cm^2 K/W at B=13.8 Tesla. The preliminary dynamic measurements near T_λ with a heat current and reduced gravity will also be presented. This research was supported by NASA.

Small helium-cooled infrared telescope experiment for Spacelab-2 (IRT)

NASA Technical Reports Server (NTRS)

Fazio, Giovanni G.

1990-01-01

The Infrared Telescope (IRT) experiment, flown on Spacelab-2, was used to make infrared measurements between 2 and 120 microns. The objectives were multidisciplinary in nature with astrophysical goals of mapping the diffuse cosmic emission and extended infrared sources and technical goals of measuring the induced Shuttle environment, studying properties of superfluid helium in space, and testing various infrared telescope system designs. Astrophysically, new data were obtained on the structure of the Galaxy at near-infrared wavelengths. A summary of the large scale diffuse near-infrared observations of the Galaxy by the IRT is presented, as well as a summary of the preliminary results obtained from this data on the structure of the galactic disk and bulge. The importance of combining CO and near-infrared maps of similar resolution to determine a 3-D model of galactic extinction is demonstrated. The IRT data are used, in conjunction with a proposed galactic model, to make preliminary measurements of the global scale parameters of the Galaxy. During the mission substantial amounts of data were obtained concerning the induced Shuttle environment. An experiment was also performed to measure spacecraft glow in the IR.

Design, integration and preliminary results of the IXV Catalysis experiment

NASA Astrophysics Data System (ADS)

Viladegut, Alan; Panerai, F.; Chazot, O.; Pichon, T.; Bertrand, P.; Verdy, C.; Coddet, C.

2017-06-01

The CATalytic Experiment (CATE) is an in-flight demonstration of catalysis effects at the surface of thermal protection materials. A high-catalytic coating was applied over the baseline ceramic material on the windward side of the intermediate experimental vehicle (IXV). The temperature jump due to different catalytic activities was detected during re-entry through measurements made with near-surface thermocouples on the windward side of the vehicle. The experiment aimed at contributing to the development and validation of gas/surface interaction models for re-entry applications. The present paper summarizes the design of CATE and its integration on the windward side of the IXV. Results of a qualification campaign at the Plasmatron facility of the von Karman Institute for Fluid Dynamics are presented. They provided an experimental evidence of the temperature jump at the low-to-high catalytic interface of the heat shield under aerothermal conditions relevant to the actual IXV flight. These tests also gave confidence so that the high-catalytic patch would not endanger the integrity of the vehicle and the safety of the mission. A preliminary assessment of flight data from the thermocouple measurements shows consistency with results of the qualification tests.

STEP Experiment Requirements

NASA Technical Reports Server (NTRS)

Brumfield, M. L. (Compiler)

1984-01-01

A plan to develop a space technology experiments platform (STEP) was examined. NASA Langley Research Center held a STEP Experiment Requirements Workshop on June 29 and 30 and July 1, 1983, at which experiment proposers were invited to present more detailed information on their experiment concept and requirements. A feasibility and preliminary definition study was conducted and the preliminary definition of STEP capabilities and experiment concepts and expected requirements for support services are presented. The preliminary definition of STEP capabilities based on detailed review of potential experiment requirements is investigated. Topics discussed include: Shuttle on-orbit dynamics; effects of the space environment on damping materials; erectable beam experiment; technology for development of very large solar array deployers; thermal energy management process experiment; photovoltaic concentrater pointing dynamics and plasma interactions; vibration isolation technology; flight tests of a synthetic aperture radar antenna with use of STEP.

Preliminary Results of NASA's First Autonomous Formation Flying Experiment: Earth Observing-1 (EO-1)

NASA Technical Reports Server (NTRS)

Folta, David; Hawkins, Albin

2001-01-01

NASA's first autonomous formation flying mission is completing a primary goal of demonstrating an advanced technology called enhanced formation flying. To enable this technology, the Guidance, Navigation, and Control center at the Goddard Space Flight Center has implemented an autonomous universal three-axis formation flying algorithm in executive flight code onboard the New Millennium Program's (NMP) Earth Observing-1 (EO-1) spacecraft. This paper describes the mathematical background of the autonomous formation flying algorithm and the onboard design and presents the preliminary validation results of this unique system. Results from functionality assessment and autonomous maneuver control are presented as comparisons between the onboard EO-1 operational autonomous control system called AutoCon(tm), its ground-based predecessor, and a stand-alone algorithm.

Experience of suicidal thoughts: a discourse analytic study.

PubMed

Galasiński, Dariusz; Ziółkowska, Justyna

2013-01-01

In this paper we explore the relationship between current psychiatric thinking on suicide and service users' accounts of suicidal ideation and suicide attempts. The data comes from recordings of psychiatric interviews collected in three psychiatric hospitals in Poland. Assuming a constructionist view of discourse we argue that the literature on suicide ignores and simplifies the experience of those who think about suicide and attempt to commit it, and constructs their experiences as a homogeneous group of 'thoughts' with only limited content. We also offer a preliminary insight into the complexity of 'suicide thoughts', as narrated by those reporting them. We demonstrate that they are marginalized and made relatively irrelevant in the accounts of attempted suicide. Additionally, we demonstrate that while women construct suicide attempts (whether actually attempted in the end or not) as at least potentially beyond their control, men's narratives show them in control of the attempt, as if choosing an available option. We conclude by exploring possibilities of further qualitative discourse analytic research which builds on the findings we present here.

Effect of salt on the response of birds to sucrose

USGS Publications Warehouse

Rogers, J.G.; Maller, O.

1973-01-01

The preference of male red-winged blackbirds for solutions of sucrose and sucrose with 0.03 M sodium chloride was tested, using a two-bottle choice test. Preliminary experiments demonstrated that the birds were indifferent to 0.03 M NaCl in water. Both control and experimental animals exhibited indifference to the solutions at the lowest concentration and aversion at the highest. The data suggest that the added sodium chloride makes the sucrose stimulus more discriminable.

Seismo-acoustic ray model benchmarking against experimental tank data.

PubMed

Camargo Rodríguez, Orlando; Collis, Jon M; Simpson, Harry J; Ey, Emanuel; Schneiderwind, Joseph; Felisberto, Paulo

2012-08-01

Acoustic predictions of the recently developed traceo ray model, which accounts for bottom shear properties, are benchmarked against tank experimental data from the EPEE-1 and EPEE-2 (Elastic Parabolic Equation Experiment) experiments. Both experiments are representative of signal propagation in a Pekeris-like shallow-water waveguide over a non-flat isotropic elastic bottom, where significant interaction of the signal with the bottom can be expected. The benchmarks show, in particular, that the ray model can be as accurate as a parabolic approximation model benchmarked in similar conditions. The results of benchmarking are important, on one side, as a preliminary experimental validation of the model and, on the other side, demonstrates the reliability of the ray approach for seismo-acoustic applications.

Dense gamma-ray and pair creation using ultra-intense lasers

NASA Astrophysics Data System (ADS)

Liang, Edison; Lo, Willie; Hasson, Hannah; Dyer, Gilliss; Clarke, Taylor; Fasanelli, Fabio; Yao, Kelly; Marchenka, Ilija; Henderson, Alexander; Dashko, Andriy; Zhang, Yuling; Ditmire, Todd

2016-10-01

We report recent results of gamma-ray and e +e- pair creation experiments using the Texas Petawatt laser (TPW) in Austin and the Trident laser at LANL irradiating solid high-Z targets. In addition to achieving record high densities of emerging gamma-rays and pairs at TPW, we measured in detail the spectra of hot electrons, positrons, and gamma-rays, and studied their spectral variation with laser and target parameters. A new type of gamma-ray spectrometer, called the scintillator attenuation spectrometer (SAS), was successfully demonstrated in Trident experiments in 2015. We will discuss the design and results of the SAS. Preliminary results of new experiments at TPW carried out in the summer of 2016 will also be presented.

Prevalidation in pharmaceutical analysis. Part I. Fundamentals and critical discussion.

PubMed

Grdinić, Vladimir; Vuković, Jadranka

2004-05-28

A complete prevalidation, as a basic prevalidation strategy for quality control and standardization of analytical procedure was inaugurated. Fast and simple, the prevalidation methodology based on mathematical/statistical evaluation of a reduced number of experiments (N < or = 24) was elaborated and guidelines as well as algorithms were given in detail. This strategy has been produced for the pharmaceutical applications and dedicated to the preliminary evaluation of analytical methods where linear calibration model, which is very often occurred in practice, could be the most appropriate to fit experimental data. The requirements presented in this paper should therefore help the analyst to design and perform the minimum number of prevalidation experiments needed to obtain all the required information to evaluate and demonstrate the reliability of its analytical procedure. In complete prevalidation process, characterization of analytical groups, checking of two limiting groups, testing of data homogeneity, establishment of analytical functions, recognition of outliers, evaluation of limiting values and extraction of prevalidation parameters were included. Moreover, system of diagnosis for particular prevalidation step was suggested. As an illustrative example for demonstration of feasibility of prevalidation methodology, among great number of analytical procedures, Vis-spectrophotometric procedure for determination of tannins with Folin-Ciocalteu's phenol reagent was selected. Favourable metrological characteristics of this analytical procedure, as prevalidation figures of merit, recognized the metrological procedure as a valuable concept in preliminary evaluation of quality of analytical procedures.

SUMS preliminary design and data analysis development. [shuttle upper atmosphere mass spectrometer experiment

NASA Technical Reports Server (NTRS)

Hinson, E. W.

1981-01-01

The preliminary analysis and data analysis system development for the shuttle upper atmosphere mass spectrometer (SUMS) experiment are discussed. The SUMS experiment is designed to provide free stream atmospheric density, pressure, temperature, and mean molecular weight for the high altitude, high Mach number region.

The 30/20 GHz demonstration system SSUS-D/BSE

NASA Technical Reports Server (NTRS)

1981-01-01

The systems consisting of a 30/20 GHz communication satellite featuring a multiple fixed beam and scanning beam antenna, SS-TDMA, onboard processing and high power TWT's and IMPATT amplifiers, a trunking space-diversity Earth station, a customer premise system (CPS) portable Earth station and a Master Control Station. Hardware, software and personnel are included to build and launch one satellite and to carry on a two year experimentation and demonstration period of advanced Ka-band systems concepts and technology. Included are first level plans identifying all tasks, a schedule for system development and an assessment of critical technology and risk and a preliminary experiments plan.

A T0/Trigger detector for the External Target Experiment at CSR

NASA Astrophysics Data System (ADS)

Hu, D.; Shao, M.; Sun, Y.; Li, C.; Chen, H.; Tang, Z.; Zhang, Y.; Zhou, J.; Zeng, H.; Zhao, X.; You, W.; Song, G.; Deng, P.; Lu, J.; Zhao, L.

2017-06-01

A new T0/Trigger detector based on multi-gap resistive plate chamber (MRPC) technology has been constructed and tested for the external target experiment (ETE) at HIRFL-CSR. It measures the multiplicity and timing information of particles produced in heavy-ion collisions at the target region, providing necessary event collision time (T0) and collision centrality with high precision. Monte-Carlo simulation shows a time resolution of several tens of picosecond can be achieved at central collisions. The experimental tests have been performed for this prototype detector at the CSR-ETE. The preliminary results are shown to demonstrate the performance of the T0/Trigger detector.

College curriculum-sharing via CTS. [Communications Technology Satellite

NASA Technical Reports Server (NTRS)

Hudson, H. E.; Guild, P. D.; Coll, D. C.; Lumb, D. R.

1975-01-01

Domestic communication satellites and video compression techniques will increase communication channel capacity and reduce cost of video transmission. NASA Ames Research Center, Stanford University and Carleton University are participants in an experiment to develop, demonstrate, and evaluate college course sharing techniques via satellite using video compression. The universities will exchange televised seminar and lecture courses via CTS. The experiment features real-time video compression with channel coding and quadra-phase modulation for reducing transmission bandwidth and power requirements. Evaluation plans and preliminary results of Carleton surveys on student attitudes to televised teaching are presented. Policy implications for the U.S. and Canada are outlined.

Analytical and experimental investigation of liquid double drop dynamics: Preliminary design for space shuttle experiments

NASA Technical Reports Server (NTRS)

1981-01-01

The preliminary grant assessed the use of laboratory experiments for simulating low g liquid drop experiments in the space shuttle environment. Investigations were begun of appropriate immiscible liquid systems, design of experimental apparatus and analyses. The current grant continued these topics, completed construction and preliminary testing of the experimental apparatus, and performed experiments on single and compound liquid drops. A continuing assessment of laboratory capabilities, and the interests of project personnel and available collaborators, led to, after consultations with NASA personnel, a research emphasis specializing on compound drops consisting of hollow plastic or elastic spheroids filled with liquids.

The lived experience of working as a musician with an injury.

PubMed

Guptill, Christine

2011-01-01

Research and clinical experience have shown that musicians are at risk of acquiring playing-related injuries. This paper explores findings from a qualitative research study examining the lived experience of professional instrumental musicians with playing-related injuries, which has thus far been missing from the performing arts health literature. This study employed a phenomenological methodology influenced by van Manen to examine the lived experiences of professional musicians with playing-related injuries. Ten professional musicians in Ontario, Canada were interviewed about their experiences as musicians with playing-related injuries. Six of the participants later attended a focus group where preliminary findings were presented. The findings demonstrate a need for education about risk and prevention of injuries that could be satisfied by healthcare professionals and music educators. The practice and training of healthcare professionals should include the "tactful" (van Manen) delivery of care for this important and vulnerable population.

Experiences with a Barista Robot, FusionBot

NASA Astrophysics Data System (ADS)

Limbu, Dilip Kumar; Tan, Yeow Kee; Wong, Chern Yuen; Jiang, Ridong; Wu, Hengxin; Li, Liyuan; Kah, Eng Hoe; Yu, Xinguo; Li, Dong; Li, Haizhou

In this paper, we describe the implemented service robot, called FusionBot. The goal of this research is to explore and demonstrate the utility of an interactive service robot in a smart home environment, thereby improving the quality of human life. The robot has four main features: 1) speech recognition, 2) object recognition, 3) object grabbing and fetching and 4) communication with a smart coffee machine. Its software architecture employs a multimodal dialogue system that integrates different components, including spoken dialog system, vision understanding, navigation and smart device gateway. In the experiments conducted during the TechFest 2008 event, the FusionBot successfully demonstrated that it could autonomously serve coffee to visitors on their request. Preliminary survey results indicate that the robot has potential to not only aid in the general robotics but also contribute towards the long term goal of intelligent service robotics in smart home environment.

MA-NOTMP: A Triazacyclononane Trimethylphosphinate Based Bifunctional Chelator for Gallium Radiolabelling of Biomolecules.

PubMed

Poty, Sophie; Désogère, Pauline; Šimeček, Jakub; Bernhard, Claire; Goncalves, Victor; Goze, Christine; Boschetti, Frédéric; Notni, Johannes; Wester, Hans J; Denat, Franck

2015-09-01

In the past few years, gallium-68 has demonstrated significant potential as a radioisotope for positron emission tomography (PET), and the optimization of chelators for gallium coordination is a major goal in the development of radiopharmaceuticals. Methylaminotriazacyclononane trimethylphosphinate (MA-NOTMP), a new C-functionalized triazacyclononane derivative with phosphinate pendant arms, presents excellent coordination properties for (68) Ga (low ligand concentration, labelling at low pH even at room temperature). A "ready-to-be-grafted" bifunctional chelating agent (p-NCS-Bz-MA-NOTMP) was prepared to allow (68) Ga labelling of sensitive biological vectors. Conjugation to a bombesin(7-14) derivative was performed, and preliminary in vitro experiments demonstrated the potential of MA-NOTMP in the development of radiopharmaceuticals. This new chelator is therefore of major interest for labelling sensitive biomolecules, and further in vivo experiments will soon be performed. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Overview of the Lockheed Martin Compact Fusion Reactor (CFR) Project

NASA Astrophysics Data System (ADS)

McGuire, Thomas

2017-10-01

The Lockheed Martin Compact Fusion Reactor (CFR) Program endeavors to quickly develop a compact fusion power plant with favorable commercial economics and military utility. The CFR uses a diamagnetic, high beta, magnetically encapsulated, linear ring cusp plasma confinement scheme. Major project activities will be reviewed, including the T4B and T5 plasma heating experiments. The goal of the experiments is to demonstrate a suitable plasma target for heating experiments, to characterize the behavior of plasma sources in the CFR configuration and to then heat the plasma with neutral beams, with the plasma transitioning into the high Beta confinement regime. The design and preliminary results of the experiments will be presented, including discussion of predicted behavior, plasma sources, heating mechanisms, diagnostics suite and relevant numerical modeling. ©2017 Lockheed Martin Corporation. All Rights Reserved.

Cone-beam reconstruction for the two-circles-plus-one-line trajectory

NASA Astrophysics Data System (ADS)

Lu, Yanbin; Yang, Jiansheng; Emerson, John W.; Mao, Heng; Zhou, Tie; Si, Yuanzheng; Jiang, Ming

2012-05-01

The Kodak Image Station In-Vivo FX has an x-ray module with cone-beam configuration for radiographic imaging but lacks the functionality of tomography. To introduce x-ray tomography into the system, we choose the two-circles-plus-one-line trajectory by mounting one translation motor and one rotation motor. We establish a reconstruction algorithm by applying the M-line reconstruction method. Numerical studies and preliminary physical phantom experiment demonstrate the feasibility of the proposed design and reconstruction algorithm.

Work Experiences of People with Mental Illness in Malaysia: A Preliminary Qualitative Study

ERIC Educational Resources Information Center

Boo, Su-Lyn; Loong, Jaymee; Ng, Wai-Sheng

2011-01-01

This is a preliminary qualitative study, using a basic interpretive approach, to investigate the work experiences of people with mental illness in Malaysia. Six females and four males (aged 30-70) from a residential home for the mentally ill participated in semi-structured interviews. Three inter-relating themes emerged, namely the experience of…

Gd uptake experiments for preliminary set of functionalized adsorbents

DOE Data Explorer

Clinton Noack

2015-03-16

These data summarize adsorption experiments conducted with Gd in 0.5 M NaCl. Results represent preliminary, proof-of-concept data utilizing fine-powder silica gel as the adsorbent support. Future testing will focus on larger, application-appropriate beads.

Preliminary Advanced Colloids Experiment

NASA Image and Video Library

2011-09-29

ISS029-E-011867 (29 Sept. 2011) --- NASA astronaut Mike Fossum, Expedition 29 commander, works with the Light Microscopy Module (LMM) control box in the Destiny laboratory of the International Space Station in preparation for another session with the Preliminary Advanced Colloids Experiment (PACE) hardware.

Replicating the Z iron opacity experiments on the NIF

NASA Astrophysics Data System (ADS)

Perry, T. S.; Heeter, R. F.; Opachich, Y. P.; Ross, P. W.; Kline, J. L.; Flippo, K. A.; Sherrill, M. E.; Dodd, E. S.; DeVolder, B. G.; Cardenas, T.; Archuleta, T. N.; Craxton, R. S.; Zhang, R.; McKenty, P. W.; Garcia, E. M.; Huffman, E. J.; King, J. A.; Ahmed, M. F.; Emig, J. A.; Ayers, S. L.; Barrios, M. A.; May, M. J.; Schneider, M. B.; Liedahl, D. A.; Wilson, B. G.; Urbatsch, T. J.; Iglesias, C. A.; Bailey, J. E.; Rochau, G. A.

2017-06-01

X-ray opacity is a crucial factor of all radiation-hydrodynamics calculations, yet it is one of the least validated of the material properties in the simulation codes. Recent opacity experiments at the Sandia Z-machine have shown up to factors of two discrepancies between theory and experiment, casting doubt on the validity of the opacity models. Therefore, a new experimental opacity platform is being developed on the National Ignition Facility (NIF) not only to verify the Z-machine experimental results but also to extend the experiments to other temperatures and densities. The first experiments will be directed towards measuring the opacity of iron at a temperature of ∼160 eV and an electron density of ∼7 × 1021 cm-3. Preliminary experiments on NIF have demonstrated the ability to create a sufficiently bright point backlighter using an imploding plastic capsule and also a hohlraum that can heat the opacity sample to the desired conditions. The first of these iron opacity experiments is expected to be performed in 2017.

Preliminary analysis of LDEF instrument A0187-1: Chemistry of Micrometeoroids Experiment

NASA Technical Reports Server (NTRS)

Hoerz, Friedrich; Bernhard, Ronald P.; Warren, Jack; See, Thomas H.; Brownlee, Donald E.; Laurance, Mark R.; Messenger, Scott; Peterson, Robert B.

1992-01-01

The Chemistry of Micrometeoroids Experiment (CME) exposed approximately 0.8 sq. m of gold on the Long Duration Exposure Facility's (LDEF's) trailing edge (location A03) and approximately 1.1 sq. m of aluminum in the forward-facing A11 location. The most significant results to date relate to the discovery of unmelted pyroxene and olivine fragments associated with natural cosmic dust impacts. The latter are sufficiently large for detailed phase studies, and they serve to demonstrate that recovery of unmelted dust fragments is a realistic prospect for further dust experiments that will employ more advanced collector media. We also discovered that man-made debris impacts occur on the LDEF's trailing edge with substantially higher frequency than expected, suggesting that orbital debris in highly elliptical orbits may have been somewhat underestimated.

Gd uptake experiments for preliminary set of functionalized adsorbents (with content model)

DOE Data Explorer

Clinton Noack

2015-03-16

These data summarize adsorption experiments conducted with Gd in 0.5 M NaCl. Results represent preliminary, proof-of-concept data utilizing fine-powder silica gel as the adsorbent support. Future testing will focus on larger, application-appropriate beads.

Space vehicle integrated thermal protection/structural/meteoroid protection system, volume 1

NASA Technical Reports Server (NTRS)

Bartlett, D. H.; Zimmerman, D. K.

1973-01-01

A program was conducted to determine the merit of a combined structure/thermal meteoroid protection system for a cryogenic vehicle propulsion module. Structural concepts were evaluated to identify least weight designs. Thermal analyses determined optimum tank arrangements and insulation materials. Meteoroid penetration experiments provided data for design of protection systems. Preliminary designs were made and compared on the basis of payload capability. Thermal performance tests demonstrated heat transfer rates typical for the selected design. Meteoroid impact tests verified the protection characteristics. A mockup was made to demonstrate protection system installation. The best design found combined multilayer insulation with a truss structure vehicle body. The multilayer served as the thermal/meteoroid protection system.

Preliminary Field Demonstration of Passive Radio Sounding Using the Sun as a Signal for Echo Detection

NASA Astrophysics Data System (ADS)

Peters, S. T.; Schroeder, D. M.; Romero-Wolf, A.; Haynes, M.

2017-12-01

The Radar for Icy Moon Exploration (RIME) and the Radar for Europa Assessment and Sounding: Ocean to Near-surface (REASON) have been identified as potential candidates for the implementation of passive sounding as additional observing modes for the ESA and NASA missions to Ganymede and Europa. Recent work has shown the theoretical potential for Jupiter's decametric radiation to be used as a source for passive radio sounding of its icy moons. We are further developing and adapting this geophysical approach for use in terrestrial glaciology. Here, we present results from preliminary field testing of a prototype passive radio sounder from cliffs along the California coast. This includes both using a Lloyd's mirror to measure the Sun's direct path and its reflection off the ocean's surface and exploiting autocorrelation to detect the delay time of the echo. This is the first in-situ demonstration of the autocorrelation-based passive-sounding approach using an astronomical white noise signal. We also discuss preliminary field tests on rougher terrestrial and subglacial surfaces, including at Store Glacier in Greenland. Additionally, we present modeling and experimental results that demonstrate the feasibility of applying presumming approaches to the autocorrelations to achieve coherent gain from an inherently random signal. We note that while recording with wider bandwidths and greater delays places fundamental limits on the Lloyd's mirror approach, our new autocorrelation method has no such limitation. Furthermore, we show how achieving wide bandwidths via spectral-stitching methods allows us to obtain a finer range resolution than given by the receiver's instantaneous bandwidth. Finally, we discuss the potential for this technique to eliminate the need for active transmitters in certain types of ice sounding experiments, thereby reducing the complexity, power consumption, and cost of systems and observations.

Preliminary drop-tower experiments on liquid-interface geometry in partially filled containers at zero gravity

NASA Technical Reports Server (NTRS)

Smedley, G.

1990-01-01

Plexiglass containers with rounded trapezoidal cross sections were designed and built to test the validity of Concus and Finn's existence theorem (1974, 1983) for a bounded free liquid surface at zero gravity. Experiments were carried out at the NASA Lewis two-second drop tower. Dyed ethanol-water solutions and three immiscible liquid pairs, with one liquid dyed, were tested. High-speed movies were used to record the liquid motion. Liquid rose to the top of the smaller end of the containers when the contact angle was small enough, in agreement with the theory. Liquid interface motion demonstrated a strong dependence on physical properties, including surface roughness and contamination.

Airborne LIDAR Measurements of Water Vapor, Ozone, Clouds, and Aerosols in the Tropics Near Central America During the TC4 Experiment

NASA Technical Reports Server (NTRS)

Kooi, Susan; Fenn, Marta; Ismail, Syed; Ferrare, Richard; Hair, John; Browell, Edward; Notari, Anthony; Butler, Carolyn; Burton, Sharon; Simpson, Steven

2008-01-01

Large scale distributions of ozone, water vapor, aerosols, and clouds were measured throughout the troposphere by two NASA Langley lidar systems on board the NASA DC-8 aircraft as part of the Tropical Composition, Cloud, and Climate Coupling Experiment (TC4) over Central and South America and adjacent oceans in the summer of 2007. Special emphasis was placed on the sampling of convective outflow and transport, sub-visible cirrus clouds, boundary layer aerosols, Saharan dust, volcanic emissions, and urban and biomass burning plumes. This paper presents preliminary results from this campaign, and demonstrates the value of coordinated measurements by the two lidar systems.

Optimal conditions for tissue perforation using high intensity focused ultrasound

NASA Astrophysics Data System (ADS)

Mochizuki, Takashi; Kihara, Taizo; Ogawa, Kouji; Tanabe, Ryoko; Yosizawa, Shin; Umemura, Shin-ichiro; Kakimoto, Takashi; Yamashita, Hiromasa; Chiba, Toshio

2012-10-01

To perforate tissue lying deep part in body, a large size transducer was assembled by combining four spherical-shaped transducers, and the optimal conditions for tissue perforation have studied using ventricle muscle of chicken as a target. The ex vivo experiments showed that ventricle muscle was successfully perforated both when it was exposed to High Intensity Focused Ultrasound (HIFU) directly and when it was exposed to HIFU through atrial muscle layer. Moreover, it was shown that calculated acoustic power distributions are well similar to the perforation patterns, and that the acoustic energy distributes very complexly near the focus. Lastly, perforation on the living rabbit bladder wall was demonstrated as a preliminary in vivo experiment.

β-Decay Studies of r-Process Nuclei Using the Advanced Implantation Detector Array (AIDA)

NASA Astrophysics Data System (ADS)

Griffin, C. J.; Davinson, T.; Estrade, A.; Braga, D.; Burrows, I.; Coleman-Smith, P. J.; Grahn, T.; Grant, A.; Harkness-Brennan, L. J.; Kiss, G.; Kogimtzis, M.; Lazarus, I. H.; Letts, S. C.; Liu, Z.; Lorusso, G.; Matsui, K.; Nishimura, S.; Page, R. D.; Prydderch, M.; Phong, V. H.; Pucknell, V. F. E.; Rinta-Antila, S.; Roberts, O. J.; Seddon, D. A.; Simpson, J.; Thomas, S. L.; Woods, P. J.

Thought to produce around half of all isotopes heavier than iron, the r-process is a key mechanism for nucleosynthesis. However, a complete description of the r-process is still lacking and many unknowns remain. Experimental determination of β-decay half-lives and β-delayed neutron emission probabilities along the r-process path would help to facilitate a greater understanding of this process. The Advanced Implantation Detector Array (AIDA) represents the latest generation of silicon implantation detectors for β-decay studies with fast radioactive ion beams. Preliminary results from commissioning experiments demonstrate successful operation of AIDA and analysis of the data obtained during the first official AIDA experiments is now under-way.

Towards sub-100 fs multi-GW pulses directly emitted from a Thulium-doped fiber CPA system

NASA Astrophysics Data System (ADS)

Gaida, C.; Gebhardt, M.; Stutzki, F.; Jauregui, C.; Limpert, J.; Tünnermann, A.

2017-02-01

Experimental demonstrations of Tm-doped fiber amplifiers (typically in CW- or narrow-band pulsed operation) span a wavelength range going from about 1700 nm to well beyond 2000 nm. Thus, it should be possible to obtain a bandwidth of more than 100 nm, which would enable sub-100 fs pulse duration in an efficient, linear amplification scheme. In fact, this would allow the emission of pulses with less than 20 optical cycles directly from a Tm-doped fiber system, something that seems to be extremely challenging for other dopants in a fused silica fiber. In this contribution, we summarize the current development of our Thulium-doped fiber CPA system, demonstrate preliminary experiments for further scaling and discuss important design factors for the next steps. The current single-channel laser system presented herein delivers a pulse-peak power of 2 GW and a nearly transform-limited pulse duration of 200 fs in combination with 28.7 W of average power. Special care has been taken to reduce the detrimental impact of water vapor absorption by placing the whole system in a dry atmosphere housing (<0.1% rel. humidity) and by using a sufficiently long wavelength (1920-1980 nm). The utilization of a low-pressure chamber in the future will allow for the extension of the amplification bandwidth. Preliminary experiments demonstrating a broader amplification bandwidth that supports almost 100 fs pulse duration and average power scaling to < 100W have already been performed. Based on these results, a Tm-doped fiber CPA with sub-100 fs pulse duration, multi-GW pulse peak power and >100 W average power can be expected in the near future.

Zero-gravity cloud physics laboratory: Experiment program definition and preliminary laboratory concept studies

NASA Technical Reports Server (NTRS)

Eaton, L. R.; Greco, E. V.

1973-01-01

The experiment program definition and preliminary laboratory concept studies on the zero G cloud physics laboratory are reported. This program involves the definition and development of an atmospheric cloud physics laboratory and the selection and delineations of a set of candidate experiments that must utilize the unique environment of zero gravity or near zero gravity.

Vestibular Function Research (VFR) experiment. Phase B: Design definition study

NASA Technical Reports Server (NTRS)

1978-01-01

The Vestibular Functions Research (VFR) Experiment was established to investigate the neurosensory and related physiological processes believed to be associated with the space flight nausea syndrome and to develop logical means for its prediction, prevention and treatment. The VFR Project consists of ground and spaceflight experimentation using frogs as specimens. The phase B Preliminary Design Study provided for the preliminary design of the experiment hardware, preparation of performance and hardware specification and a Phase C/D development plan, establishment of STS (Space Transportation System) interfaces and mission operations, and the study of a variety of hardware, experiment and mission options. The study consist of three major tasks: (1) mission mode trade-off; (2) conceptual design; and (3) preliminary design.

In situ fluidization for peat bed rupture, and preliminary economic analysis.

PubMed

Niven, R K; Khalili, N

2002-11-01

This study concerns in situ fluidization (ISF), a new remediation method with potential application to the remediation of NAPL and heavy metal contaminants, by their release from the fluidized zone generated by a water jet. The present study examines the effect of ISF on layers of peat, of significance owing to its role as an important NAPL and metal contaminant trap. Once trapped, such contaminants are not readily accessible by most remedial methods, due to the low permeability and diffusivity of the peat. A simple tank experiment is used to demonstrate rupture of a peat layer by ISF, with removal of the peat as elutriated fines and segregated peat chunks. The application of ISF in the field is then examined by three field trials in uncontaminated sands, in both saturated and unsaturated conditions. Fluidized depths of up to 1.9 m in the saturated zone (with refusal on a peat layer) and 2.5 m in the unsaturated zone (no refusal) were attained, using a 1.9-m-long, 50 mm diameter jet operated at 5-13 1 s(-1). Pulses of dark turbidity and shell fragments in the effluent indicated the rupture of peat and shelly layers. The experiments demonstrate the hydraulic viability of ISF in the field, and its ability to remove peat-based contaminants. The issues of appropriate jet design and water generation during ISF are discussed, followed by a preliminary economic analysis of ISF relative to existing remediation methods.

Preliminary design polymeric materials experiment. [for space shuttles and Spacelab missions

NASA Technical Reports Server (NTRS)

Mattingly, S. G.; Rude, E. T.; Marshner, R. L.

1975-01-01

A typical Advanced Technology Laboratory mission flight plan was developed and used as a guideline for the identification of a number of experiment considerations. The experiment logistics beginning with sample preparation and ending with sample analysis are then overlaid on the mission in order to have a complete picture of the design requirements. The results of this preliminary design study fall into two categories. First specific preliminary designs of experiment hardware which is adaptable to a variety of mission requirements. Second, identification of those mission considerations which affect hardware design and will require further definition prior to final design. Finally, a program plan is presented which will provide the necessary experiment hardware in a realistic time period to match the planned shuttle flights. A bibliography of all material reviewed and consulted but not specifically referenced is provided.

Space station definitions, design, and development. Task 5: Multiple arm telerobot coordination and control: Manipulator design methodology

NASA Technical Reports Server (NTRS)

Stoughton, R. M.

1990-01-01

A proposed methodology applicable to the design of manipulator systems is described. The current design process is especially weak in the preliminary design phase, since there is no accepted measure to be used in trading off different options available for the various subsystems. The design process described uses Cartesian End-Effector Impedance as a measure of performance for the system. Having this measure of performance, it is shown how it may be used to determine the trade-offs necessary to the preliminary design phase. The design process involves three main parts: (1) determination of desired system performance in terms of End-Effector Impedance; (2) trade-off design options to achieve this desired performance; and (3) verification of system performance through laboratory testing. The design process is developed using numerous examples and experiments to demonstrate the feasability of this approach to manipulator design.

Researches on Preliminary Chemical Reactions in Spark-Ignition Engines

NASA Technical Reports Server (NTRS)

Muehlner, E.

1943-01-01

Chemical reactions can demonstrably occur in a fuel-air mixture compressed in the working cylinder of an Otto-cycle (spark ignition) internal-combustion engine even before the charge is ignited by the flame proceeding from the sparking plug. These are the so-called "prelinminary reactions" ("pre-flame" combustion or oxidation), and an exact knowledge of their characteristic development is of great importance for a correct appreciation of the phenomena of engine-knock (detonation), and consequently for its avoidance. Such reactions can be studied either in a working engine cylinder or in a combustion bomb. The first method necessitates a complicated experimental technique, while the second has the disadvantage of enabling only a single reaction to be studied at one time. Consequently, a new series of experiments was inaugurated, conducted in a motored (externally-driven) experimental engine of mixture-compression type, without ignition, the resulting preliminary reactions being detectable and measurable thermometrically.

The development of laser speckle velocimetry for the study of vortical flows

NASA Technical Reports Server (NTRS)

Krothapalli, A.

1991-01-01

A research program was undertaken to develop a new experimental technique commonly known as particle image displacement velocity (PIVD) to measure an instantaneous two dimensional velocity field in a selected plane of flow field. This technique was successfully developed and applied to the study of several aerodynamic problems. A detailed description of the technique and a broad review of all the research activity carried out in this field are reported. A list of technical publications is also provided. The application of PIDV to unsteady flows with large scale structures is demonstrated in a study of the temporal evolution of the flow past an impulsively started circular cylinder. The instantaneous two dimensional flow in the transition region of a rectangular air jet was measured using PIDV and the details are presented. This experiment clearly demonstrates the PIDV capability in the measurement of turbulent flows. Preliminary experiments were also conducted to measure the instantaneous flow over a circular bump in a transonic flow. Several other experiments now routinely use PIDV as a non-intrustive measurement technique to obtain instantaneous two dimensional velocity fields.

Experiments on Adaptive Techniques for Host-Based Intrusion Detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

DRAELOS, TIMOTHY J.; COLLINS, MICHAEL J.; DUGGAN, DAVID P.

2001-09-01

This research explores four experiments of adaptive host-based intrusion detection (ID) techniques in an attempt to develop systems that can detect novel exploits. The technique considered to have the most potential is adaptive critic designs (ACDs) because of their utilization of reinforcement learning, which allows learning exploits that are difficult to pinpoint in sensor data. Preliminary results of ID using an ACD, an Elman recurrent neural network, and a statistical anomaly detection technique demonstrate an ability to learn to distinguish between clean and exploit data. We used the Solaris Basic Security Module (BSM) as a data source and performed considerablemore » preprocessing on the raw data. A detection approach called generalized signature-based ID is recommended as a middle ground between signature-based ID, which has an inability to detect novel exploits, and anomaly detection, which detects too many events including events that are not exploits. The primary results of the ID experiments demonstrate the use of custom data for generalized signature-based intrusion detection and the ability of neural network-based systems to learn in this application environment.« less

A Preliminary Comparison of Three Dimensional Particle Tracking and Sizing using Plenoptic Imaging and Digital In-line Holography

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guildenbecher, Daniel Robert; Munz, Elise Dahnke; Farias, Paul Abraham

2015-12-01

Digital in-line holography and plenoptic photography are two techniques for single-shot, volumetric measurement of 3D particle fields. Here we present a preliminary comparison of the two methods by applying plenoptic imaging to experimental configurations that have been previously investigated with digital in-line holography. These experiments include the tracking of secondary droplets from the impact of a water drop on a thin film of water and tracking of pellets from a shotgun. Both plenoptic imaging and digital in-line holography successfully quantify the 3D nature of these particle fields. This includes measurement of the 3D particle position, individual particle sizes, and three-componentmore » velocity vectors. For the initial processing methods presented here, both techniques give out-of-plane positional accuracy of approximately 1-2 particle diameters. For a fixed image sensor, digital holography achieves higher effective in-plane spatial resolutions. However, collimated and coherent illumination makes holography susceptible to image distortion through index of refraction gradients, as demonstrated in the shotgun experiments. On the other hand, plenotpic imaging allows for a simpler experimental configuration. Furthermore, due to the use of diffuse, white-light illumination, plenoptic imaging is less susceptible to image distortion in the shotgun experiments. Additional work is needed to better quantify sources of uncertainty, particularly in the plenoptic experiments, as well as develop data processing methodologies optimized for the plenoptic measurement.« less

A Preliminary Comparison of Three Dimensional Particle Tracking and Sizing using Plenoptic Imaging and Digital In-line Holography [PowerPoint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guildenbecher, Daniel Robert; Munz, Elise Dahnke; Farias, Paul Abraham

2015-12-01

Digital in-line holography and plenoptic photography are two techniques for single-shot, volumetric measurement of 3D particle fields. Here we present a preliminary comparison of the two methods by applying plenoptic imaging to experimental configurations that have been previously investigated with digital in-line holography. These experiments include the tracking of secondary droplets from the impact of a water drop on a thin film of water and tracking of pellets from a shotgun. Both plenoptic imaging and digital in-line holography successfully quantify the 3D nature of these particle fields. This includes measurement of the 3D particle position, individual particle sizes, and three-componentmore » velocity vectors. For the initial processing methods presented here, both techniques give out-of-plane positional accuracy of approximately 1-2 particle diameters. For a fixed image sensor, digital holography achieves higher effective in-plane spatial resolutions. However, collimated and coherent illumination makes holography susceptible to image distortion through index of refraction gradients, as demonstrated in the shotgun experiments. On the other hand, plenotpic imaging allows for a simpler experimental configuration. Furthermore, due to the use of diffuse, white-light illumination, plenoptic imaging is less susceptible to image distortion in the shotgun experiments. Additional work is needed to better quantify sources of uncertainty, particularly in the plenoptic experiments, as well as develop data processing methodologies optimized for the plenoptic measurement.« less

Experiments in DIII-D Toward Achieving Rapid Shutdown with Runaway Electron Suppression

NASA Astrophysics Data System (ADS)

Hollmann, E. M.

2009-11-01

For safe discharge shutdown in future large tokamaks in the event of an unavoidable disruption, it is important to develop rapid (˜ several ms)shutdown methods to avoid large runaway electron currents, which pose a serious threat to plasma facing components. Prevention of runaway current formation has been proposed by either increasing electron-electron collisionality with massive particle injection, or magnetically by using externally applied non-axisymmetric fields to increase radial diffusive losses of a runaway seed population. Experiments studying both approaches have been pursued in the DIII-D tokamak. For collisional suppression, three different rapid shutdown methods are being investigated: massive gas injection, massive shattered cryogenic pellet injection, and polystyrene shell pellet injection. First-of-kind demonstrations of fast shutdowns were produced by 3000 Torr-l (0.8-g) shattered D2 pellets and large, 10-mm diameter, 0.3-g polystyrene shell pellets filled with boron powder. The application of external magnetic perturbations shows promising preliminary results in suppressing seed runaway electrons, although lack of repeatability in the runaway seed term made these results challenging to interpret. Experiments have been performed to help understand how runaways form and are transported during rapid shutdown. These experiments confirm that the commonly used 0D loop voltage + Dreicer evaporation picture of runaway seed formation is not applicable here, with relativistic E > 0.5,MeV electrons forming before any external loop voltage appears. Present applications of 0D, 1D, and 2D models to the rapid shutdown and runaway confinement experiments, as well as preliminary extrapolations to ITER, will be discussed.

Development of a near-infrared spectroscopic system for monitoring urine glucose level for the use of long-term home healthcare

NASA Astrophysics Data System (ADS)

Tanaka, Shinobu; Hayakawa, Yuuto; Ogawa, Mitsuhiro; Yamakoshi, Ken-ichi

2010-08-01

We have been developing a new technique for measuring urine glucose concentration using near infrared spectroscopy (NIRS) in conjunction with the Partial Least Square (PLS) method. In the previous study, we reported some results of preliminary experiments for assessing feasibility of this method using a FT-IR spectrometer. In this study, considering practicability of the system, a flow-through cell with the optical path length of 10 mm was newly introduced. Accuracy of the system was verified by the preliminary experiments using urine samples. From the results obtained, it was clearly demonstrated that the present method had a capability of predicting individual urine glucose level with reasonable accuracy (the minimum value of standard error of prediction: SEP = 22.3 mg/dl) and appeared to be a useful means for long-term home health care. However, mean value of SEP obtained by the urine samples from ten subjects was not satisfactorily low (53.7 mg/dl). For improving the accuracy, (1) mechanical stability of the optical system should be improved, (2) the method for normalizing the spectrum should be reconsidered, and (3) the number of subject should be increased.

A mobile telephone-based SMS and internet survey system for self-assessment in Australian anaesthesia: experience of a single practitioner.

PubMed

Belavy, D

2014-11-01

Self-assessment and audit in anaesthesia require a systematic approach to postoperative data collection. The increasing prevalence of mobile internet technology offers a new data collection method for anaesthetists. In this paper, a system for mobile internet data collection is described and the preliminary experience with its use is presented. The system was developed by the author and combined an open source survey application and a short message service (SMS) gateway to send SMS messages to patients after their anaesthesia and surgery. The messages requested patients to complete an online Quality of Recovery survey questionnaire if they had a smartphone. The results were immediately available. A preliminary survey of consenting patients with available mobile telephone numbers in a private practice was undertaken by the author. A total of 123 procedures were eligible for follow-up and survey requests were sent to 94 patients. Sixty-five surveys were completed. This represents 69% of surveys requested, demonstrating that mobile phone technology can be used to provide significant amounts of data for quality assurance. However, the implementation of a mobile internet data collection system requires consideration of privacy principles, security and ethical handling of data.

Synthetic aperture ultrasound imaging with a ring transducer array: preliminary ex vivo results.

PubMed

Qu, Xiaolei; Azuma, Takashi; Yogi, Takeshi; Azuma, Shiho; Takeuchi, Hideki; Tamano, Satoshi; Takagi, Shu

2016-10-01

The conventional medical ultrasound imaging has a low lateral spatial resolution, and the image quality depends on the depth of the imaging location. To overcome these problems, this study presents a synthetic aperture (SA) ultrasound imaging method using a ring transducer array. An experimental ring transducer array imaging system was constructed. The array was composed of 2048 transducer elements, and had a diameter of 200 mm and an inter-element pitch of 0.325 mm. The imaging object was placed in the center of the ring transducer array, which was immersed in water. SA ultrasound imaging was then employed to scan the object and reconstruct the reflection image. Both wire phantom and ex vivo experiments were conducted. The proposed method was found to be capable of producing isotropic high-resolution images of the wire phantom. In addition, preliminary ex vivo experiments using porcine organs demonstrated the ability of the method to reconstruct high-quality images without any depth dependence. The proposed ring transducer array and SA ultrasound imaging method were shown to be capable of producing isotropic high-resolution images whose quality was independent of depth.

Development of a liquid lithium thin film for use as a heavy ion beam stripper.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Momozaki, Y.; Nolen, J.; Reed, C.

2009-04-01

A series of experiments was performed to investigate the feasibility of a liquid lithium thin film for a charge stripper in a high-power heavy ion linac. Various preliminary experiments using simulants were first conducted to determine the film formation scheme, to investigate the film stability, and to obtain the design parameters for a liquid lithium thin film system. Based on the results from these preliminary studies, a prototypical, high pressure liquid lithium system was constructed to demonstrate liquid lithium thin film formation. This system was capable of driving liquid lithium at {approx}< 300 C and up to 13.9 MPa (2000more » psig) through a nozzle opening as large as 1 mm (40 mil) in diameter. This drive pressure corresponds to a Li velocity of >200 m/s. A thin lithium film of 9 mm in width at velocity of {approx}58 m/s was produced. Its thickness was estimated to be roughly {approx}< 13 {micro}m. High vacuum was maintained in the area of the film. This type of liquid metal thin film may also be used in other high power beam applications such as for intense X-ray or neutron sources.« less

Feasibility and systems definition study for microwave multi-application payload (MMAP)

NASA Technical Reports Server (NTRS)

Horton, J. B.; Allen, C. C.; Massaro, M. J.; Zemany, J. L.; Murrell, J. W.; Stanhouse, R. W.; Condon, G. P.; Stone, R. F.

1977-01-01

There were three Shuttle/Spacelab experiments: adaptive multibeam phased array antenna (AMPA) experiment, electromagnetic environment experiment (EEE), and millimeter wave communications experiment (MWCE). Work on the AMPA experiment was completed. Results included are definition of operating modes, sequence of operation, radii of operation about several ground stations, signal format, foot prints of typical orbits and preliminary definition of ground and user terminals. Definition of the MOD I EEE included conceptual hardware designs, spacelab interfaces, preliminary data handling methods, experiment tests and verification, and EMC studies. The MWCE was defined conceptually for a steerable high gain antenna.

Survey of CELSS Concepts and Preliminary Research in Japan

NASA Technical Reports Server (NTRS)

Ohya, H.; Oshima, T.; Nitta, K.

1985-01-01

Agricultural and other experiments relating to the development of a controlled ecological life support system (CELSS) were proposed. The engineering feasibility of each proposal was investigated by a CELSS experiment concept met study group. The CELSS experiment concept to clarify the goals of CELSS and to determine three phases to achieve the goals. The resulting phases, or missions, and preliminary proposals and studies needed to develop a CELSS are described.

Integrated support structure for GASCAN 2

NASA Technical Reports Server (NTRS)

1990-01-01

The focus of the Worcester Polytechnic Institute (WPI) Advanced Space Design Program was the preliminary design of the Integrated Support Structure for GASCAN II, a Get Away Special canister donated by the MITRE Corporation. Two teams of three students each worked on the support structure. There was a structural design team and a thermal design team. The structure will carry three experiments also undergoing preliminary design this year, the mu-gravity Ignition Experiment, the Rotational Flow in Low Gravity Experiment, and the Ionospheric Properties and Propagation Experiment. The structural design team was responsible for the layout of the GASCAN and the preliminary design of the structure itself. They produced the physical interface specifications defining the baseline weights and volumes for the equipment and produced layout drawings of the system. The team produced static and modal finite element analysis of the structure using ANSYS. The thermal design team was responsible for the power and timing requirements of the payload and for the identification and preliminary analysis of potential thermal problems. The team produced the power, timing, and energy interface specifications and assisted in the development of the specification of the battery pack. The thermal parameters of each experiment were cataloged and the experiments were subjected to worst case heat transfer scenarios.

A field study of wind over a simulated block building

NASA Technical Reports Server (NTRS)

Frost, W.; Shahabi, A. M.

1977-01-01

A full-scale field study of the wind over a simulated two-dimensional building is reported. The study develops an experiment to investigate the structure and magnitude of the wind fields. A description of the experimental arrangement, the type and expected accuracy of the data, and the range of the data are given. The data are expected to provide a fundamental understanding of mean wind and turbulence structure of the wind field around the bluff body. Preliminary analysis of the data demonstrates the reliability and completeness of the data in this regard.

Multidisciplinary Design, Analysis, and Optimization Tool Development Using a Genetic Algorithm

NASA Technical Reports Server (NTRS)

Pak, Chan-gi; Li, Wesley

2009-01-01

Multidisciplinary design, analysis, and optimization using a genetic algorithm is being developed at the National Aeronautics and Space Administration Dryden Flight Research Center (Edwards, California) to automate analysis and design process by leveraging existing tools to enable true multidisciplinary optimization in the preliminary design stage of subsonic, transonic, supersonic, and hypersonic aircraft. This is a promising technology, but faces many challenges in large-scale, real-world application. This report describes current approaches, recent results, and challenges for multidisciplinary design, analysis, and optimization as demonstrated by experience with the Ikhana fire pod design.!

A preliminary damage tolerance methodology for composite structures

NASA Technical Reports Server (NTRS)

Wilkins, D. J.

1983-01-01

The certification experience for the primary, safety-of-flight composite structure applications on the F-16 is discussed. The rationale for the selection of delamination as the major issue for damage tolerance is discussed, as well as the modeling approach selected. The development of the necessary coupon-level data base is briefly summarized. The major emphasis is on the description of a full-scale fatigue test where delamination growth was obtained to demonstrate the validity of the selected approach. A summary is used to review the generic features of the methodology.

Probabilistic cross-link analysis and experiment planning for high-throughput elucidation of protein structure.

PubMed

Ye, Xiaoduan; O'Neil, Patrick K; Foster, Adrienne N; Gajda, Michal J; Kosinski, Jan; Kurowski, Michal A; Bujnicki, Janusz M; Friedman, Alan M; Bailey-Kellogg, Chris

2004-12-01

Emerging high-throughput techniques for the characterization of protein and protein-complex structures yield noisy data with sparse information content, placing a significant burden on computation to properly interpret the experimental data. One such technique uses cross-linking (chemical or by cysteine oxidation) to confirm or select among proposed structural models (e.g., from fold recognition, ab initio prediction, or docking) by testing the consistency between cross-linking data and model geometry. This paper develops a probabilistic framework for analyzing the information content in cross-linking experiments, accounting for anticipated experimental error. This framework supports a mechanism for planning experiments to optimize the information gained. We evaluate potential experiment plans using explicit trade-offs among key properties of practical importance: discriminability, coverage, balance, ambiguity, and cost. We devise a greedy algorithm that considers those properties and, from a large number of combinatorial possibilities, rapidly selects sets of experiments expected to discriminate pairs of models efficiently. In an application to residue-specific chemical cross-linking, we demonstrate the ability of our approach to plan experiments effectively involving combinations of cross-linkers and introduced mutations. We also describe an experiment plan for the bacteriophage lambda Tfa chaperone protein in which we plan dicysteine mutants for discriminating threading models by disulfide formation. Preliminary results from a subset of the planned experiments are consistent and demonstrate the practicality of planning. Our methods provide the experimenter with a valuable tool (available from the authors) for understanding and optimizing cross-linking experiments.

THE MORPHOLOGICAL BASIS FOR OLFACTORY PERCEPTION OF STEROIDS DUING AGONISTIC BEHAVIOR IN LOBSTER: PRELIMINARY EXPERIMENTS

EPA Science Inventory

The morphological basis for olfactory perception of steroids during agonistic behavior in lobsters: preliminary experiments. Borsay Horowitz, DJ1, Kass-Simon, G2, Coglianese, D2, Martin, L2, Boseman, M2, Cromarty, S3, Randall, K3, Fini, A.3 1US EPA, NHEERL, ORD, Atlantic Ecology...

Global Experience: The Development and Preliminary Evaluation of a Programme Designed to Enhance Students' Global Engagement

ERIC Educational Resources Information Center

Feast, Vicki; Collyer-Braham, Sarah; Bretag, Tracey

2011-01-01

This paper reports on the development and preliminary evaluation of "Global Experience", an innovative programme at the University of South Australia designed to broaden students' intercultural engagement through a range of international experiential activities. The paper provides the rationale for the establishment of the programme…

Simple Carotid-Sparing Intensity-Modulated Radiotherapy Technique and Preliminary Experience for T1-2 Glottic Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rosenthal, David I., E-mail: dirosenthal@mdanderson.or; Fuller, Clifton D.; Barker, Jerry L.

2010-06-01

Purpose: To investigate the dosimetry and feasibility of carotid-sparing intensity-modulated radiotherapy (IMRT) for early glottic cancer and to report preliminary clinical experience. Methods and Materials: Digital Imaging and Communications in Medicine radiotherapy (DICOM-RT) datasets from 6 T1-2 conventionally treated glottic cancer patients were used to create both conventional IMRT plans. We developed a simplified IMRT planning algorithm with three fields and limited segments. Conventional and IMRT plans were compared using generalized equivalent uniform dose and dose-volume parameters for in-field carotid arteries, target volumes, and organs at risk. We have treated 11 patients with this simplified IMRT technique. Results: Intensity-modulated radiotherapymore » consistently reduced radiation dose to the carotid arteries (p < 0.05) while maintaining the clinical target volume coverage. With conventional planning, median carotid V35, V50, and V63 were 100%, 100%, and 69.0%, respectively. With IMRT planning these decreased to 2%, 0%, and 0%, respectively (p < 0.01). Radiation planning and treatment times were similar for conventional radiotherapy and IMRT. Treatment results have been excellent thus far. Conclusions: Intensity-modulated radiotherapy significantly reduced unnecessary radiation dose to the carotid arteries compared with conventional lateral fields while maintaining clinical target volume coverage. Further experience and longer follow-up will be required to demonstrate outcomes for cancer control and carotid artery effects.« less

Test description and preliminary pitot-pressure surveys for Langley Test Technique Demonstrator at Mach 6

NASA Technical Reports Server (NTRS)

Everhart, Joel L.; Ashby, George C., Jr.; Monta, William J.

1992-01-01

A propulsion/airframe integration experiment conducted in the NASA Langley 20-Inch Mach 6 Tunnel using a 16.8-in.-long version of the Langley Test Technique Demonstrator configuration with simulated scramjet propulsion is described. Schlieren and vapor screen visualization of the nozzle flow field is presented and correlated with pitot-pressure flow-field surveys. The data were obtained at nominal free-stream conditions of Re = 2.8 x 10 exp 6 and a nominal engine total pressure of 100 psia. It is concluded that pitot-pressure surveys coupled to schlieren and vapor-screen photographs, and oil flows have revealed flow features including vortices, free shear layers, and shock waves occurring in the model flow field.

Panic-Focused Psychodynamic Psychotherapy in a Woman with Panic Disorder and Generalized Anxiety Disorder

PubMed Central

Sandberg, Larry; Busch, Fredric; Schneier, Franklin; Gerber, Andrew; Caligor, Eve; Milrod, Barbara

2016-01-01

Panic-focused psychodynamic psychotherapy (PFPP) is a 24-session, twice-weekly (12 weeks), manualized psychoanalytic psychotherapy with demonstrated preliminary efficacy for panic disorder (PD).1,2 Given the substantial morbidity and the health care utilization of the PD population,3,4 coupled with the sizable proportion of such patients who do not respond (or respond inadequately) to alternate treatments (cognitive-behavioral therapy [CBT] and drug therapy),5–7 PFPP may offer clinicians an additional tool for their therapeutic armamentarium. It may also facilitate a rapprochement between academic psychiatry and psychodynamic perspectives, and a reassessment of the role of psychodynamic therapy as part of the educational experience of residents in training—an experience that has diminished over two decades. PMID:23030215

Testing of Safety-Critical Software Embedded in an Artificial Heart

NASA Astrophysics Data System (ADS)

Cha, Sungdeok; Jeong, Sehun; Yoo, Junbeom; Kim, Young-Gab

Software is being used more frequently to control medical devices such as artificial heart or robotic surgery system. While much of software safety issues in such systems are similar to other safety-critical systems (e.g., nuclear power plants), domain-specific properties may warrant development of customized techniques to demonstrate fitness of the system on patients. In this paper, we report results of a preliminary analysis done on software controlling a Hybrid Ventricular Assist Device (H-VAD) developed by Korea Artificial Organ Centre (KAOC). It is a state-of-the-art artificial heart which completed animal testing phase. We performed software testing in in-vitro experiments and animal experiments. An abnormal behaviour, never detected during extensive in-vitro analysis and animal testing, was found.

Consort 1 flight results: a synopsis.

PubMed

Wessling, F C; Lundquist, C A; Maybee, G W

1990-09-01

Consort 1 was the first low gravity materials processing payload to be launched by a commercially licensed rocket in the U.S.A. It carried six experiments which operated as planned during approx. 7 min of suborbital, low gravity flight (10(-5) g) and were returned in excellent condition to the investigators within 4 h of launch. Nearly 150 physical samples supported by measurements and photographs made during the flight were obtained for analysis. In addition to the experimental data returned, the success of Consort 1 demonstrated the ability of industry, working with university centers and government agencies, to rapidly prepare and launch payloads. A brief description of the rocket flight and payload configuration is given. Experiment objectives and methods are described and preliminary results and conclusions are presented.

Shuttle Imaging Radar - Geologic applications

NASA Technical Reports Server (NTRS)

Macdonald, H.; Bridges, L.; Waite, W.; Kaupp, V.

1982-01-01

The Space Shuttle, on its second flight (November 12, 1981), carried the first science and applications payload which provided an early demonstration of Shuttle's research capabilities. One of the experiments, the Shuttle Imaging Radar-A (SIR-A), had as a prime objective to evaluate the capability of spaceborne imaging radars as a tool for geologic exploration. The results of the experiment will help determine the value of using the combination of space radar and Landsat imagery for improved geologic analysis and mapping. Preliminary analysis of the Shuttle radar imagery with Seasat and Landsat imagery from similar areas provides evidence that spaceborne radars can significantly complement Landsat interpretation, and vastly improve geologic reconnaissance mapping in those areas of the world that are relatively unmapped because of perpetual cloud cover.

Markov chains for testing redundant software

NASA Technical Reports Server (NTRS)

White, Allan L.; Sjogren, Jon A.

1988-01-01

A preliminary design for a validation experiment has been developed that addresses several problems unique to assuring the extremely high quality of multiple-version programs in process-control software. The procedure uses Markov chains to model the error states of the multiple version programs. The programs are observed during simulated process-control testing, and estimates are obtained for the transition probabilities between the states of the Markov chain. The experimental Markov chain model is then expanded into a reliability model that takes into account the inertia of the system being controlled. The reliability of the multiple version software is computed from this reliability model at a given confidence level using confidence intervals obtained for the transition probabilities during the experiment. An example demonstrating the method is provided.

Towards monitoring real-time cellular response using an integrated microfluidics-MALDI/nESI-ion mobility-mass spectrometry platform

PubMed Central

Enders, Jeffrey R.; Marasco, Christina C.; Kole, Ayeeshik; Nguyen, Bao; Sundarapandian, Sevugarajan; Seale, Kevin T.; Wikswo, John P.; McLean, John A.

2014-01-01

The combination of microfluidic cell trapping devices with ion mobility-mass spectrometry offers the potential for elucidating in real time the dynamic responses of small populations of cells to paracrine signals, changes in metabolite levels, and delivery of drugs and toxins. Preliminary experiments examining peptides in methanol and recording the interactions of yeast and Jurkat cells with their superfusate have identified instrumental setup and control parameters and on-line desalting procedures. Numerous initial experiments demonstrate and validate this new instrumental platform. Future outlooks and potential applications are addressed, specifically how this instrumentation may be used for fully automated systems biology studies of the significantly interdependent, dynamic internal workings of cellular metabolic and signaling pathways. PMID:21073240

Preliminary design and hazards report. Boiling Reactor Experiment V (BORAX V)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rice, R. E.

1960-02-01

The preliminary objectives of the proposed BORAX V program are to test nuclear superheating concepts and to advance the technology of boiling-water-reactor design by performing experiments which will improve the understanding of factors limiting the stability of boiling reactors at high power densities. The reactor vessel is a cylinder with ellipsoidal heads, made of carbon steel clad internally with stainless steel. Each of the three cores is 24 in. high and has an effective diameter of 39 in. This is a preliminary report. (W.D.M.)

Inviscid Limit for Damped and Driven Incompressible Navier-Stokes Equations in mathbb R^2

NASA Astrophysics Data System (ADS)

Ramanah, D.; Raghunath, S.; Mee, D. J.; Rösgen, T.; Jacobs, P. A.

2007-08-01

Experiments to demonstrate the use of the background-oriented schlieren (BOS) technique in hypersonic impulse facilities are reported. BOS uses a simple optical set-up consisting of a structured background pattern, an electronic camera with a high shutter speed and a high intensity light source. The visualization technique is demonstrated in a small reflected shock tunnel with a Mach 4 conical nozzle, nozzle supply pressure of 2.2 MPa and nozzle supply enthalpy of 1.8 MJ/kg. A 20° sharp circular cone and a model of the MUSES-C re-entry body were tested. Images captured were processed using PIV-style image analysis to visualize variations in the density field. The shock angle on the cone measured from the BOS images agreed with theoretical calculations to within 0.5°. Shock standoff distances could be measured from the BOS image for the re-entry body. Preliminary experiments are also reported in higher enthalpy facilities where flow luminosity can interfere with imaging of the background pattern.

Characterization of bone microstructure using photoacoustic spectrum analysis

NASA Astrophysics Data System (ADS)

Feng, Ting; Kozloff, Kenneth M.; Xu, Guan; Du, Sidan; Yuan, Jie; Deng, Cheri X.; Wang, Xueding

2015-03-01

Osteoporosis is a progressive bone disease that is characterized by a decrease in bone mass and deterioration in microarchitecture. This study investigates the feasibility of characterizing bone microstructure by analyzing the frequency spectrum of the photoacoustic signals from the bone. Modeling and numerical simulation of photoacoustic signals and their frequency-domain analysis were performed on trabecular bones with different mineral densities. The resulting quasilinear photoacoustic spectra were fit by linear regression, from which spectral parameter slope can be quantified. The modeling demonstrates that, at an optical wavelength of 685 nm, bone specimens with lower mineral densities have higher slope. Preliminary experiment on osteoporosis rat tibia bones with different mineral contents has also been conducted. The finding from the experiment has a good agreement with the modeling, both demonstrating that the frequency-domain analysis of photoacoustic signals can provide objective assessment of bone microstructure and deterioration. Considering that photoacoustic measurement is non-ionizing, non-invasive, and has sufficient penetration in both calcified and noncalcified tissues, this new technology holds unique potential for clinical translation.

Ascending and Descending in Virtual Reality: Simple and Safe System Using Passive Haptics.

PubMed

Nagao, Ryohei; Matsumoto, Keigo; Narumi, Takuji; Tanikawa, Tomohiro; Hirose, Michitaka

2018-04-01

This paper presents a novel interactive system that provides users with virtual reality (VR) experiences, wherein users feel as if they are ascending/descending stairs through passive haptic feedback. The passive haptic stimuli are provided by small bumps under the feet of users; these stimuli are provided to represent the edges of the stairs in the virtual environment. The visual stimuli of the stairs and shoes, provided by head-mounted displays, evoke a visuo-haptic interaction that modifies a user's perception of the floor shape. Our system enables users to experience all types of stairs, such as half-turn and spiral stairs, in a VR setting. We conducted a preliminary user study and two experiments to evaluate the proposed technique. The preliminary user study investigated the effectiveness of the basic idea associated with the proposed technique for the case of a user ascending stairs. The results demonstrated that the passive haptic feedback produced by the small bumps enhanced the user's feeling of presence and sense of ascending. We subsequently performed an experiment to investigate an improved viewpoint manipulation method and the interaction of the manipulation and haptics for both the ascending and descending cases. The experimental results demonstrated that the participants had a feeling of presence and felt a steep stair gradient under the condition of haptic feedback and viewpoint manipulation based on the characteristics of actual stair walking data. However, these results also indicated that the proposed system may not be as effective in providing a sense of descending stairs without an optimization of the haptic stimuli. We then redesigned the shape of the small bumps, and evaluated the design in a second experiment. The results indicated that the best shape to present haptic stimuli is a right triangle cross section in both the ascending and descending cases. Although it is necessary to install small protrusions in the determined direction, by using this optimized shape the users feeling of presence of the stairs and the sensation of walking up and down was enhanced.

Replicating the Z iron opacity experiments on the NIF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perry, T. S.; Heeter, R. F.; Opachich, Y. P.

Here, X-ray opacity is a crucial factor of all radiation-hydrodynamics calculations, yet it is one of the least validated of the material properties in the simulation codes. Recent opacity experiments at the Sandia Z-machine have shown up to factors of two discrepancies between theory and experiment, casting doubt on the validity of the opacity models. Therefore, a new experimental opacity platform is being developed on the National Ignition Facility (NIF) not only to verify the Z-machine experimental results but also to extend the experiments to other temperatures and densities. The first experiments will be directed towards measuring the opacity ofmore » iron at a temperature of ~160 eV and an electron density of ~7 x 10 21 cm -3. Preliminary experiments on NIF have demonstrated the ability to create a sufficiently bright point backlighter using an imploding plastic capsule and also a hohlraum that can heat the opacity sample to the desired conditions. The first of these iron opacity experiments is expected to be performed in 2017.« less

Replicating the Z iron opacity experiments on the NIF

DOE PAGES

Perry, T. S.; Heeter, R. F.; Opachich, Y. P.; ...

2017-05-12

Here, X-ray opacity is a crucial factor of all radiation-hydrodynamics calculations, yet it is one of the least validated of the material properties in the simulation codes. Recent opacity experiments at the Sandia Z-machine have shown up to factors of two discrepancies between theory and experiment, casting doubt on the validity of the opacity models. Therefore, a new experimental opacity platform is being developed on the National Ignition Facility (NIF) not only to verify the Z-machine experimental results but also to extend the experiments to other temperatures and densities. The first experiments will be directed towards measuring the opacity ofmore » iron at a temperature of ~160 eV and an electron density of ~7 x 10 21 cm -3. Preliminary experiments on NIF have demonstrated the ability to create a sufficiently bright point backlighter using an imploding plastic capsule and also a hohlraum that can heat the opacity sample to the desired conditions. The first of these iron opacity experiments is expected to be performed in 2017.« less

DEMONSTRATION OF FUEL CELLS TO RECOVER ENERGY FROM ANAEROBIC DIGESTER GAS - PHASE I. CONCEPTUAL DESIGN, PRELIMINARY COST, AND EVALUATION STUDY

EPA Science Inventory

The report discusses Phase I (a conceptual design, preliminary cost, and evaluation study) of a program to demonstrate the recovery of energy from waste methane produced by anaerobic digestion of waste water treatment sludge. The fuel cell is being used for this application becau...

Preliminary Flight Results of the Microelectronics and Photonics Test Bed: NASA DR1773 Fiber Optic Data Bus Experiment

NASA Technical Reports Server (NTRS)

Jackson, George L.; LaBel, Kenneth A.; Marshall, Cheryl; Barth, Janet; Seidleck, Christina; Marshall, Paul

1998-01-01

NASA Goddard Spare Flight Center's (GSFC) Dual Rate 1773 (DR1773) Experiment on the Microelectronic and Photonic Test Bed (MPTB) has provided valuable information on the performance of the AS 1773 fiber optic data bus in the space radiation environment. Correlation of preliminary experiment data to ground based radiation test results show the AS 1773 bus is employable in future spacecraft applications requiring radiation tolerant communication links.

Preliminary test results from a free-piston Stirling engine technology demonstration program to support advanced radioisotope space power applications

NASA Astrophysics Data System (ADS)

White, Maurice A.; Qiu, Songgang; Augenblick, Jack E.

2000-01-01

Free-piston Stirling engines offer a relatively mature, proven, long-life technology that is well-suited for advanced, high-efficiency radioisotope space power systems. Contracts from DOE and NASA are being conducted by Stirling Technology Company (STC) for the purpose of demonstrating the Stirling technology in a configuration and power level that is representative of an eventual space power system. The long-term objective is to develop a power system with an efficiency exceeding 20% that can function with a high degree of reliability for up to 15 years on deep space missions. The current technology demonstration convertors (TDC's) are completing shakedown testing and have recently demonstrated performance levels that are virtually identical to projections made during the preliminary design phase. This paper describes preliminary test results for power output, efficiency, and vibration levels. These early results demonstrate the ability of the free-piston Stirling technology to exceed objectives by approximately quadrupling the efficiency of conventional radioisotope thermoelectric generators (RTG's). .

Characterization of the visibility of wildfire smoke clouds

NASA Astrophysics Data System (ADS)

de Vries, Jan S.; den Breejen, Eric

1993-09-01

In order to investigate the smoke cloud visibility of small wildfires a series of controlled biomass burning experiments has been carried out to investigate the characteristics of smoke clouds using various remote sensing techniques. These techniques include simultaneous scattering and transmission measurements in four wavelength bands, near-, mid-, and far- infrared video imagery, high resolution Fourier spectrometry, and particle size distribution measurements. The characterization and, in particular, knowledge on the contrast of smoke from small, beginning wildfires against a vegetation background is required in order to predict the performance of autonomous surveillance systems. This paper describes the preliminary analysis of experiments which have been carried out in Ypenburg (the Netherlands) in 1992. The results of these experiments are used to estimate the wildfire detection efficiency of a demonstration sensor which is being developed in a project financed by the Commission of the European Communities and by Bosschap. The autonomous wildfire detection sensor is described.

Experimental apparatus with full optical access for combustion experiments with laminar flames from a single circular nozzle at elevated pressures.

PubMed

Joo, Peter H; Gao, Jinlong; Li, Zhongshan; Aldén, Marcus

2015-03-01

The design and features of a high pressure chamber and burner that is suitable for combustion experiments at elevated pressures are presented. The high pressure combustion apparatus utilizes a high pressure burner that is comprised of a chamber burner module and an easily accessible interchangeable burner module to add to its flexibility. The burner is well suited to study both premixed and non-premixed flames. The optical access to the chamber is provided through four viewports for direct visual observations and optical-based diagnostic techniques. Auxiliary features include numerous access ports and electrical connections and as a result, the combustion apparatus is also suitable to work with plasmas and liquid fuels. Images of methane flames at elevated pressures up to 25 atm and preliminary results of optical-based measurements demonstrate the suitability of the high pressure experimental apparatus for combustion experiments.

Application of the NASA airborne oceanographic lidar to the mapping of chlorophyll and other organic pigments

NASA Technical Reports Server (NTRS)

Hoge, F. E.; Swift, R. N.

1981-01-01

Laser fluorosensing techniques used for the airborne measurement of chlorophyll a and other naturally occurring waterborne pigments are reviewed. Previous experiments demonstrating the utility of the airborne oceanographic lidar (AOL) for assessment of various marine parameters are briefly discussed. The configuration of the AOL during the NOAA/NASA Superflux experiments is described. The participation of the AOL in these experiments is presented and the preliminary results are discussed. The importance of multispectral receiving capability in a laser fluorosensing system for providing reproducible measurements over wide areas having spatial variations in water column transmittance properties is addressed. This capability minimizes the number of truthing points required and is usable even in shallow estuarine areas where resuspension of bottom sediment is common. Finally, problems encountered on the Superflux missions and the resulting limitations on the AOL data sets are addressed and feasible solutions to these problems are provided.

Theory and Experimental Program for p-B11 Fusion with the Dense Plasma Focus

NASA Astrophysics Data System (ADS)

Lerner, Eric J.; Krupakar Murali, S.; Haboub, A.

2011-10-01

Lawrenceville Plasma Physics Inc. has initiated a 2-year-long experimental project to test the scientific feasibility of achieving controlled fusion using the dense plasma focus (DPF) device with hydrogen-boron (p-B11) fuel. The goals of the experiment are: first, to confirm the achievement of high ion and electron energies observed in previous experiments from 2001; second, to greatly increase the efficiency of energy transfer into the plasmoid where the fusion reactions take place; third, to achieve the high magnetic fields (>1 GG) needed for the quantum magnetic field effect, which will reduce cooling of the plasma by X-ray emission; and finally, to use p-B11 fuel to demonstrate net energy gain. The experiments are being conducted with a newly constructed dense plasma focus in Middlesex, NJ which is expected to generate peak currents in excess of 2 MA. Some preliminary results are reported.

The Mars Observer Ka-band link experiment

NASA Technical Reports Server (NTRS)

Rebold, T. A.; Kwok, A.; Wood, G. E.; Butman, S.

1994-01-01

The Ka-Band Link Experiment was the first demonstration of a deep-space communications link in the 32- to 35-GHz band (Ka-band). It was carried out using the Mars Observer spacecraft while the spacecraft was in the cruise phase of its mission and using a 34-meter beam-waveguide research and development antenna at the Goldstone complex of the DSN. The DSN has been investigating the performance benefits of a shift from X-band (8.4 GHz) to Ka-band (32 GHz) for deep-space communications. The fourfold increase in frequency is expected to offer a factor of 3 to 10 improvement (5 to 10 dB) in signal strength for a given spacecraft transmitter power and antenna size. Until recently, the expected benefits were based on performance studies, with an eye to implementing such a link, but theory was transformed to reality when a 33.7-GHz Ka-band signal was received from the spacecraft by DSS 13. This article describes the design and implementation of the Ka-Band Link Experiment from the spacecraft to the DSS-13 system, as well as results from the Ka-band telemetry demonstration, ranging demonstration, and long-term tracking experiment. Finally, a preliminary analysis of comparative X- and Ka-band tracking results is included. These results show a 4- to 7-dB advantage for Ka-band using the system at DSS 13, assuming such obstacles as antenna pointing loss and power conversion loss are overcome.

Interactive Lecture Experiments in Large Introductory Physics Classes

NASA Astrophysics Data System (ADS)

Milner-Bolotin, Marina M.; Kotlicki, A.; Rieger, G.; Bates, F.; Moll, R.; McPhee, K.; Nashon, S.

2006-12-01

We describe Interactive Lecture Experiments (ILE), which build on Interactive Lecture Demonstrations proposed by Sokoloff and Thornton (2004) and extends it by providing students with the opportunity to analyze experiments demonstrated in the lecture outside of the classroom. Real time experimental data is collected, using Logger Pro combined with the digital video technology. This data is uploaded to the Internet and made available to the students for further analysis. Student learning is assessed in the following lecture using conceptual questions (clickers). The goal of this project is to use ILE to make large lectures more interactive and promote student interest in science, critical thinking and data analysis skills. We report on the systematic study conducted using the Colorado Learning Attitudes about Science Survey, Force Concept Inventory, open-ended physics problems and focus group interviews to determine the impact of ILE on student academic achievement, motivation and attitudes towards physics. Three sections of students (750 students) experienced four ILE experiments. The surveys were administered twice and academic results for students who experienced the ILE for a particular topic were compared to the students, from a different section, who did not complete the ILE for that topic. Additional qualitative data on students’ attitudes was collected using open ended survey questions and interviews. We will present preliminary conclusions about the role of ILEs as an effective pedagogy in large introductory physics courses. Sokoloff, D.R. and R.K. Thornton (2004). Interactive Lecture Demonstrations: Active Learning in Introductory Physics, J.Wiley & Sons, INC. Interactive Lecture Experiments: http://www.physics.ubc.ca/ year1lab/p100/LectureLabs/lectureLabs.html

Sodium sulfur battery flight experiment definition study

NASA Technical Reports Server (NTRS)

Chang, Rebecca R.; Minck, Robert

1989-01-01

Sodium-sulfur batteries were identified as the most likely successor to nickel-hydrogen batteries for space applications. One advantage of the Na/S battery system is that the usable specific energy is two to three times that of nickel-hydrogen batteries. This represents a significant launch cost savings or increased payload mass capabilities. Sodium-sulfur batteries support NASA OAST's proposed Civil Space Technology Initiative goal of a factor of two improvement in spacecraft power system performance, as well as the proposed Spacecraft 2000 initiative. The sodium-sulfur battery operates at between 300 and 400 C, using liquid sodium and sulfur/polysulfide electrodes and solid ceramic electrolyte. The transport of the electrode materials to the surface of the electrolyte is through wicking/capillary forces. These critical transport functions must be demonstrated under actual microgravity conditions before sodium-sulfur batteries can be confidently utilized in space. Ford Aerospace Corporation, under contract to NASA Lewis Research Center, is currently working on the sodium-sulfur battery space flight experiment definition study. The objective is to design the experiment that will demonstrate operation of the sodium-sulfur battery/cell in the space environment with particular emphasis on evaluation of microgravity effects. Experimental payload definitions were completed and preliminary designs of the experiment were defined.

FLOQSwab™: Optimisation of Procedures for the Recovery of Microbiological Samples from Surfaces

PubMed Central

Finazzi, Guido; Losio, Marina Nadia; Varisco, Giorgio

2016-01-01

The FLOQSwab™ is a specimen collection device worldwide recognised for its superior performance in the clinical diagnostics. The aim of this work was to evaluate FLOQSwab™ for the recovery of microbiological samples from surfaces compared to the traditional swab (rayon tipped swab) as per ISO 18593:2004 standard. The FLOQSwab™, thanks to its innovative manufacturing technology, allows improving the efficiency of recovery and release of analyte. The study has been divided into two experiments. In the first experiment the two swabs were evaluated for their capacity to recover and release the analyte (three different bacterial loads of Escherichia coli). In the second experiment, the two swabs were evaluated for their capacity to recover three different bacterial loads of E. coli from two different surface materials (stainless steel and polypropylene). In all experiments the flocked swab demonstrated a higher recovery rate compared to the traditional rayon tipped swab. The data obtained from this preliminary study demonstrated that the FLOQSwab™ could be a good food surfaces collection device, which improves the recovery of the analyte and thus produces accurate results. Based on the outcomes of the study, a larger field study is in progress using the FLOQSwab™ for samples collection to improve both environmental monitoring and the efficacy of the hygiene controls for food safety. PMID:27853708

Some experiences in aircraft aeroelastic design using Preliminary Aeroelastic Design of Structures (PAD)

NASA Technical Reports Server (NTRS)

Radovcich, N. A.

1984-01-01

The design experience associated with a benchmark aeroelastic design of an out of production transport aircraft is discussed. Current work being performed on a high aspect ratio wing design is reported. The Preliminary Aeroelastic Design of Structures (PADS) system is briefly summarized and some operational aspects of generating the design in an automated aeroelastic design environment are discussed.

Teaching Note--Description and Preliminary Evaluation of a Modified College Experience for Adults with Intellectual and Developmental Disabilities

ERIC Educational Resources Information Center

Remis, Kimberly; Moore, Crystal Dea; Pichardo, Julia; Rosario, Zuliany; Moore, Jeffrey Palmer

2017-01-01

This article describes the implementation and preliminary evaluation of a modified college experience for adults with intellectual and developmental disabilities (IDD) at a small liberal arts college. To increase social work students' interest in working with this population and access of people with IDD to higher education, Bridges to Skidmore…

Design of a water electrolysis flight experiment

NASA Technical Reports Server (NTRS)

Lee, M. Gene; Grigger, David J.; Thompson, C. Dean; Cusick, Robert J.

1993-01-01

Supply of oxygen (O2) and hydrogen (H2) by electolyzing water in space will play an important role in meeting the National Aeronautics and Space Administration's (NASA's) needs and goals for future space missios. Both O2 and H2 are envisioned to be used in a variety of processes including crew life support, spacecraft propulsion, extravehicular activity, electrical power generation/storage as well as in scientific experiment and manufacturing processes. The Electrolysis Performance Improvement Concept Study (EPICS) flight experiment described herein is sponsored by NASA Headquarters as a part of the In-Space Technology Experiment Program (IN-STEP). The objective of the EPICS is to further contribute to the improvement of the SEF technology, specifially by demonstrating and validating the SFE electromechanical process in microgravity as well as investigating perrformance improvements projected possible in a microgravity environment. This paper defines the experiment objective and presents the results of the preliminary design of the EPICS. The experiment will include testing three subscale self-contained SFE units: one containing baseline components, and two units having variations in key component materials. Tests will be conducted at varying current and thermal condition.

Preliminary flight results from the second U.S. Microgravity Payload (USMP-2)

NASA Technical Reports Server (NTRS)

Curreri, Peter; Reiss, Donald

1994-01-01

The second U.S. Microgravity Payload (USMP-2) was flown on the Space Shuttle in March 1994. It carried four major microgravity experiments plus a sophisticated accelerometer system to record the microgravity environment during USMP-2 operations. The USMP program is designed to accommodate experiments requiring extensive resources short of a full Spacelab mission, and the experiments are remotely operated and monitored. Results are reviewed from the four experiments: the Advanced Automated Directional Solidification Facility (AADSF), the Isothermal Dendrite Growth Experiment (IDGE), the Materiel por Etude des Phenomenes Interessant la Soldification sur Terre et en Orbite (MEPHISTO), and the Critical Fluid Light Scattering Experiment (Zeno). AASDF grew what is expected to be the largest steady-state sample ever of HgCdTe during 240 hours of operation. IDGE provided 60 growth cycles over a wide range of supercooling conditions studying the dendritic solidification of succinonitrile. MEPHISTO achieved 55 melt-solidify cycles and grew over 1 m of Bi/Sn alloy. Zeno located the critical point temperature for liquid Xe to 0.00001 K. IDGE and Zeno also provided the most extensive demonstrations to date of telescience.

Toward continuous glucose monitoring with planar modified biosensors and microdialysis. Study of temperature, oxygen dependence and in vivo experiment.

PubMed

Ricci, Francesco; Caprio, Felice; Poscia, Alessandro; Valgimigli, Francesco; Messeri, Dimitri; Lepori, Elena; Dall'Oglio, Giorgio; Palleschi, Giuseppe; Moscone, Danila

2007-04-15

Glucose biosensors based on the use of planar screen-printed electrodes modified with an electrochemical mediator and with glucose oxidase have been optimised for their application in the continuous glucose monitoring in diabetic patients. A full study of their operative stability and temperature dependence has been accomplished, thus giving useful information for in vivo applications. The effect of dissolved oxygen concentration in the working solution was also studied in order to evaluate its effect on the linearity of the sensors. Glucose monitoring performed with serum samples was performed to evaluate the effect of matrix components on operative stability and demonstrated an efficient behaviour for 72 h of continuous monitoring. Finally, these studies led to a sensor capable of detecting glucose at concentrations as low as 0.04 mM and with a good linearity up to 2.0 mM (at 37 degrees C) with an operative stability of ca. 72 h, thus demonstrating the possible application of these sensors for continuous glucose monitoring in conjunction with a microdialysis probe. Moreover, preliminary in vivo experiments for ca. 20 h have demonstrated the feasibility of this system.

"Minimally invasive video-assisted thyroidectomy. Initial experience in a general surgery department".

PubMed

Dobrinja, Chiara; Trevisan, Giuliano; Liguori, Gennaro

2009-03-01

The aim of this study is to analyze our preliminary results from minimally invasive video-assisted thyroidectomy (MIVAT) and demonstrate the feasibility of MIVAT also in non-referral centers. We report our initial experience based on a series of 47 patients selected for MIVAT at General Surgery Department of University of Trieste during a period from May 2005 to February 2007. The eligibility criteria were rigorously observed. Age, goiter volume, major diameter of the dominant nodule, operative times, pathologic findings, postoperative pain, length of hospital stay, cosmetic results, and complications were retrospectively analyzed. Thyroid lobectomy was successfully accomplished in 33 cases, total thyroidectomy in 14. Conversion to standard cervicotomy was required in three patients (6%). Mean operative time of lobectomy was 82.6 min and 118.7 for total thyroidectomy. Postoperative complications included 11 (23.4%) transient hypocalcemias, 2 (4.2%) hematomas, and 2 (4.2%) temporary laryngeal nerve palsies. None-recurrent nerve palsies was observed. The cosmetic result was excellent in most cases. Our experience demonstrates that MIVAT, after adequate training, is feasible and safe, with results comparable to conventional thyroidectomy, also in a General Surgery Department, from a dedicated team, with a sufficient and specific activity volume.

Preliminary design of flight hardware for two-phase fluid research

NASA Technical Reports Server (NTRS)

Hustvedt, D. C.; Oonk, R. L.

1982-01-01

This study defined the preliminary designs of flight software for the Space Shuttle Orbiter for three two-phase fluid research experiments: (1) liquid reorientation - to study the motion of liquid in tanks subjected to small accelerations; (2) pool boiling - to study low-gravity boiling from horizontal cylinders; and (3) flow boiling - to study low-gravity forced flow boiling heat transfer and flow phenomena in a heated horizontal tube. The study consisted of eight major tasks: reassessment of the existing experiment designs, assessment of the Spacelab facility approach, assessment of the individual carry-on approach, selection of the preferred approach, preliminary design of flight hardware, safety analysis, preparation of a development plan, estimates of detailed design, fabrication and ground testing costs. The most cost effective design approach for the experiments is individual carry-ons in the Orbiter middeck. The experiments were designed to fit into one or two middeck lockers. Development schedules for the detailed design, fabrication and ground testing ranged from 15 1/2 to 18 months. Minimum costs (in 1981 dollars) ranged from $463K for the liquid reorientation experiment to $998K for the pool boiling experiment.

Effect of descriptive information and experience on automation reliance.

PubMed

Yuviler-Gavish, Nirit; Gopher, Daniel

2011-06-01

The present research addresses the issue of reliance on decision support systems for the long-term (DSSLT), which help users develop decision-making strategies and long-term planning. It is argued that providing information about a system's future performance in an experiential manner, as compared with a descriptive manner, encourages users to increase their reliance level. Establishing appropriate reliance on DSSLT is contingent on the system developer's ability to provide users with information about the system's future performance. A sequence of three studies contrasts the effect on automation reliance of providing descriptive information versus experience for DSSLT with two different positive expected values of recommendations. Study I demonstrated that when automation reliance was determined solely on the basis of description, it was relatively low, but it increased significantly when a decision was made after experience with 50 training simulations. Participants were able to learn to increase their automation reliance levels when they encountered the same type of recommendation again. Study 2 showed that the absence of preliminary descriptive information did not affect the automation reliance levels obtained after experience. Study 3 demonstrated that participants were able to generalize their learning about increasing reliance levels to new recommendations. Using experience rather than description to give users information about future performance in DSSLT can help increase automation reliance levels. Implications for designing DSSLT and decision support systems in general are discussed.

Solar heating of common lunar minerals for the production of oxygen

NASA Technical Reports Server (NTRS)

Senior, C. L.

1991-01-01

The purpose of this work was to demonstrate the feasibility of vapor-phase reduction (pyrolysis) of lunar materials to produce oxygen. Solar furnace experiments were conducted on two common lunar minerals, ilmenite and anorthite. Thermodynamic equilibrium calculations predicted that ilmenite should show a larger pressure increase than anorthite under conditions of the experiments and this was confirmed by the experiments. The measured mass loss of the ilmenite sample was consistent with loss of oxygen by reduction of iron in the liquid phase; this result was also predicted from equilibrium calculations. Based on preliminary experiments and equilibrium calculations, the temperatures needed for pyrolysis are expected to be in the range of 2000 to 2500 K, giving total gas pressures of 0.01 to 1 torr. Bulk regolith can be used as a feedstock without extensive beneficiation. Further, selective condensation of metal-containing species from the gas phase may yield metallic iron and silicon as byproducts from the process.

5.625 Gbps bidirectional laser communications measurements between the NFIRE satellite and an optical ground station

NASA Astrophysics Data System (ADS)

Fields, Renny A.; Kozlowski, David A.; Yura, Harold T.; Wong, Robert L.; Wicker, Josef M.; Lunde, Carl T.; Gregory, Mark; Wandernoth, Bernhard K.; Heine, Frank F.; Luna, Joseph J.

2011-11-01

5.625 Gbps bidirectional laser communication at 1064 nm has been demonstrated on a repeatable basis between a Tesat coherent laser communication terminal with a 6.5 cm diameter ground aperture mounted inside the European Space Agency Optical Ground Station dome at Izana, Tenerife and a similar space-based terminal (12.4 cm diameter aperture) on the Near-Field InfraRed Experiment (NFIRE) low-earth-orbiting spacecraft. Both night and day bidirectional links were demonstrated with the longest being 177 seconds in duration. Correlation with atmospheric models and preliminary atmospheric r0 and scintillation measurements have been made for the conditions tested, suggesting that such coherent systems can be deployed successfully at still lower altitudes without resorting to the use of adaptive optics for compensation.

A Study of an Optical Lunar Surface Communications Network with High Bandwidth Direct to Earth Link

NASA Technical Reports Server (NTRS)

Wilson, K.; Biswas, A.; Schoolcraft, J.

2011-01-01

Analyzed optical DTE (direct to earth) and lunar relay satellite link analyses, greater than 200 Mbps downlink to 1-m Earth receiver and greater than 1 Mbps uplink achieved with mobile 5-cm lunar transceiver, greater than 1Gbps downlink and greater than 10 Mpbs uplink achieved with 10-cm stationary lunar transceiver, MITLL (MIT Lincoln Laboratory) 2013 LLCD (Lunar Laser Communications Demonstration) plans to demonstrate 622 Mbps downlink with 20 Mbps uplink between lunar orbiter and ground station; Identified top five technology challenges to deploying lunar optical network, Performed preliminary experiments on two of challenges: (i) lunar dust removal and (ii)DTN over optical carrier, Exploring opportunities to evaluate DTN (delay-tolerant networking) over optical link in a multi-node network e.g. Desert RATS.

Non-invasive continuous imaging of drug release from soy-based skin equivalent using wide-field interferometry

NASA Astrophysics Data System (ADS)

Gabai, Haniel; Baranes-Zeevi, Maya; Zilberman, Meital; Shaked, Natan T.

2013-04-01

We propose an off-axis interferometric imaging system as a simple and unique modality for continuous, non-contact and non-invasive wide-field imaging and characterization of drug release from its polymeric device used in biomedicine. In contrast to the current gold-standard methods in this field, usually based on chromatographic and spectroscopic techniques, our method requires no user intervention during the experiment, and only one test-tube is prepared. We experimentally demonstrate imaging and characterization of drug release from soy-based protein matrix, used as skin equivalent for wound dressing with controlled anesthetic, Bupivacaine drug release. Our preliminary results demonstrate the high potential of our method as a simple and low-cost modality for wide-field imaging and characterization of drug release from drug delivery devices.

On Subsurface Fracture Opening and Closure

NASA Astrophysics Data System (ADS)

Wang, Y.

2016-12-01

Mechanistic understanding of fracture opening and closure in geologic media is of significant importance to nature resource extraction and waste management, such as geothermal energy extraction, oil/gas production, radioactive waste disposal, and carbon sequestration and storage). A dynamic model for subsurface fracture opening and closure has been formulated. The model explicitly accounts for the stress concentration around individual aperture channels and the stress-activated mineral dissolution and precipitation. A preliminary model analysis has demonstrated the importance of the stress-activated dissolution mechanism in the evolution of fracture aperture in a stressed geologic medium. The model provides a reasonable explanation for some key features of fracture opening and closure observed in laboratory experiments, including a spontaneous switch from a net permeability reduction to a net permeability increase with no changes in a limestone fracture experiment.

Decentralized control mechanism underlying interlimb coordination of millipedes.

PubMed

Kano, Takeshi; Sakai, Kazuhiko; Yasui, Kotaro; Owaki, Dai; Ishiguro, Akio

2017-04-04

Legged animals exhibit adaptive and resilient locomotion through interlimb coordination. The long-term goal of this study is to clarify the relationship between the number of legs and the inherent decentralized control mechanism for interlimb coordination. As a preliminary step, the study focuses on millipedes as they represent the species with the greatest number of legs among various animal species. A decentralized control mechanism involving local force feedback was proposed based on the qualitative findings of behavioural experiments in which responses to the removal of part of the terrain and leg amputation were observed. The proposed mechanism was implemented in a developed millipede-like robot to demonstrate that the robot can adapt to the removal of the part of the terrain and leg amputation in a manner similar to that in behavioural experiments.

Damage Detection and Verification System (DDVS) for In-Situ Health Monitoring

NASA Technical Reports Server (NTRS)

Williams, Martha K.; Lewis, Mark; Szafran, J.; Shelton, C.; Ludwig, L.; Gibson, T.; Lane, J.; Trautwein, T.

2015-01-01

Project presentation for Game Changing Program Smart Book Release. Detection and Verification System (DDVS) expands the Flat Surface Damage Detection System (FSDDS) sensory panels damage detection capabilities and includes an autonomous inspection capability utilizing cameras and dynamic computer vision algorithms to verify system health. Objectives of this formulation task are to establish the concept of operations, formulate the system requirements for a potential ISS flight experiment, and develop a preliminary design of an autonomous inspection capability system that will be demonstrated as a proof-of-concept ground based damage detection and inspection system.

A numerical study of the hot gas environment around a STOVL aircraft in ground proximity

NASA Technical Reports Server (NTRS)

Vanoverbeke, Thomas J.; Holdeman, James D.

1988-01-01

The development of Short Takeoff Vertical Landing (STOVL) aircraft has historically been an empirical- and experience-based technology. In this study, a 3-D turbulent flow CFD code was used to calculate the hot gas environment around an STOVL aircraft operating in ground proximity. Preliminary calculations are reported for a typical STOVL aircraft configuration to identify key features of the flow field, and to demonstrate and assess the capability of current 3-D CFD codes to calculate the temperature of the gases ingested at the engine inlet as a function of flow and geometric conditions.

Fan-beam scanning laser optical computed tomography for large volume dosimetry

NASA Astrophysics Data System (ADS)

Dekker, K. H.; Battista, J. J.; Jordan, K. J.

2017-05-01

A prototype scanning-laser fan beam optical CT scanner is reported which is capable of high resolution, large volume dosimetry with reasonable scan time. An acylindrical, asymmetric aquarium design is presented which serves to 1) generate parallel-beam scan geometry, 2) focus light towards a small acceptance angle detector, and 3) avoid interference fringe-related artifacts. Preliminary experiments with uniform solution phantoms (11 and 15 cm diameter) and finger phantoms (13.5 mm diameter FEP tubing) demonstrate that the design allows accurate optical CT imaging, with optical CT measurements agreeing within 3% of independent Beer-Lambert law calculations.

Application of ERTS-1 imagery to the harvest model of the US Menhaden fishery

NASA Technical Reports Server (NTRS)

Maughan, P. M.; Marmelstein, A. D.; Temple, O. R.

1973-01-01

Preliminary results of an experiment to demonstrate the utility of ERTS-1 imagery for providing significant information to the harvest model of the menhaden industry are reported. Fisheries and related environmental data were obtained discontinuously throughout the 1973 menhaden (a surface schooling, coastal species) fishing season in Mississippi Sound. The unexpected complexity of the physical environment in Mississippi Sound precluded simplistic analysis of fish/environment relationships. Preliminary indications are that an association does exist between fish availability and differences in water transparency (turbidity) within the Sound. A clearer relationship is developing between major turbid features, imaged by ERTS-1 and location of successful fishing attempts. On all occasions where relatively cloudfree ERTS-1 overflight days coincided with fishery activity, overlays of catch location of ERTS-1 images show an association of school position with interfaces between imaged turbid features. Analysis is currently underway to determine persistence of such associations in an attempt to define minimum satellite return time necessary to maintain continuity of associations.

Bio-Aerosol Detection Using Mass Spectrometry: Public Health Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ludvigson, Laura D.

2004-01-01

I recently spent a summer as an intern at the Lawrence Livermore National Laboratory. I worked on a project involving the real-time, reagentless, single cell detection of aerosolized pathogens using a novel mass spectrometry approach called Bio-Aerosol Mass Spectrometry (BAMS). Based upon preliminary results showing the differentiation capabilities of BAMS, I would like to explore the development and use of this novel detection system in the context of both environmental and clinical sample pathogen detection. I would also like to explore the broader public health applications that a system such as BAMS might have in terms of infectious disease preventionmore » and control. In order to appreciate the potential of this instrument, I will demonstrate the need for better pathogen detection methods, and outline the instrumentation, data analysis and preliminary results that lead me toward a desire to explore this technology further. I will also discuss potential experiments for the future along with possible problems that may be encountered along the way.« less

Recent HBT results in Au+Au and p+p collisions from PHENIX

NASA Astrophysics Data System (ADS)

PHENIX Collaboration; Glenn, Andrew; PHENIX Collaboration

2009-11-01

We present Hanbury-Brown Twiss measurements from the PHENIX experiment at RHIC for final results for charged kaon pairs from s=200 GeV Au+Au collisions and preliminary results for charged pion pairs from s=200 GeVp+p collisions. We find that for kaon pairs from Au+Au, each traditional 3D Gaussian radius shows approximately the same linear increase as a function of Npart1/3. An imaging analysis reveals a significant non-Gaussian tail for r≳10 fm. The presence of a tail for kaon pairs demonstrates that similar non-Gaussian tails observed in earlier pion measurements cannot be fully explained by decays of long-lived resonances. The preliminary analysis of pions from s=200 GeV p+p minimum biased collisions show correlations which are well suited to traditional 3D HBT radii extraction via the Bowler-Sinyukov method, and we present R, R, and R as a function of mean transverse pair mass.

Early maladaptive schemas and aggressive sexual behavior: a preliminary study with male college students.

PubMed

Sigre-Leirós, Vera Lúcia; Carvalho, Joana; Nobre, Pedro

2013-07-01

The influence of adverse early attachment experiences on the development of aggressive sexual behavior has been demonstrated. Nonetheless, there is a gap in the literature regarding the conceptualization of this behavior according to developmental psychopathology models. The purpose of the present study was to investigate a potential association between Early Maladaptive Schemas (EMSs) and aggressive sexual behavior. A total of 166 male college students participated in the study. Participants were divided into two comparative groups according to data from the Sexual Experiences Survey-Short Form Perpetration (SES-SFP): Group of individuals with history of aggressive sexual behavior (N = 37) and Group of individuals without history of aggressive sexual behavior (N = 129). Aggressive sexual behavior was measured by the SES-SFP, and EMSs were measured by the Young Schema Questionnaire (YSQ-S3). Results showed that students who have committed any form of sexually aggressive behavior exhibited significantly higher levels of EMSs from the Disconnection and Rejection domain (namely, Mistrust/Abuse schema), from the Impaired Autonomy and Performance domain (namely, Dependence/Incompetence schema), and from the Overvigilance and Inhibition domain (namely, Negativity/Pessimism schema). These preliminary findings suggest that the EMSs were associated with aggressive sexual behavior, but further investigation is warranted. © 2012 International Society for Sexual Medicine.

Targeting Alertness to Improve Cognition in Older Adults: A Preliminary Report of Benefits in Executive Function and Skill Acquisition

PubMed Central

Van Vleet, Thomas M.; DeGutis, Joseph M.; Merzenich, Michael M.; Simpson, Gregory V.; Zomet, Ativ; Dabit, Sawsan

2016-01-01

Efficient self-regulation of alertness declines with age exacerbating normal declines in performance across multiple cognitive domains, including learning and skill acquisition. Previous cognitive intervention studies have shown that it is possible to enhance alertness in patients with acquired brain injury and marked attention impairments, and that this benefit generalizes to improvements in more global cognitive functions. In the current preliminary studies, we sought to test whether this approach, that targets both tonic (over a period of minutes) and phasic (moment-to-moment) alertness, can improve key executive functioning declines in older adults, and enhance the rate of skill acquisition. The results of both experiments 1 and 2 demonstrate that, compared to active control training, alertness training significantly enhanced performance in several validated executive function measures. In experiment 2, alertness training significantly improved skill acquisition compared to active control training in a well-characterized speed of processing task, with the largest benefits shown in the most challenging speed of processing blocks. The results of the current study suggest that targeting intrinsic alertness in cognitive training provides a novel approach to improve executive functions in older adults and may be a useful adjunct treatment to enhance benefits gained in other clinically validated treatments. PMID:27372902

Requirements and feasibility study of flight demonstration of Active Controls Technology (ACT) on the NASA 515 airplane

NASA Technical Reports Server (NTRS)

Gordon, C. K.

1975-01-01

A preliminary design study was conducted to evaluate the suitability of the NASA 515 airplane as a flight demonstration vehicle, and to develop plans, schedules, and budget costs for fly-by-wire/active controls technology flight validation in the NASA 515 airplane. The preliminary design and planning were accomplished for two phases of flight validation.

Preliminary design study for an atomospheric science facility

NASA Technical Reports Server (NTRS)

Hutchison, R.

1972-01-01

The activities and results of the Atmospheric Science Facility preliminary design study are reported. The objectives of the study were to define the scientific goals, to determine the range of experiment types, and to develop the preliminary instrument design requirements for a reusable, general purpose, optical research facility for investigating the earth's atmosphere from a space shuttle orbital vehicle.

["Soiuz-Apollo" experimental flight. Preliminary results of medicobiological studies, carried out during the flight of "Soiuz-19" spaceship].

PubMed

Vorob'ev, E I; Gazenko, O G; Gurovskiĭ, N N; Nefedov, Iu G; Egorov, B B

1976-01-01

The paper presents brief information on the Apollo-Soyuz test mission, its program biomedical investigations to be carried out in flight and specific medical aspects. It discusses the main tasks of the joint US-USSR experiments and Soviet experiments. It gives and analyzes preliminary results of medical monitoring and postflight examinations of the crew members.

A research experiment on facilitation and formation of joint research and development programs between government, industry, and universities: Overview, preliminary findings, and observations

NASA Technical Reports Server (NTRS)

Shariq, Syed Z.

1992-01-01

Presented is an overview of an experiment to explore the free-market approach to public-private collaboration through the development and implementation of a joint venture mechanism to enable formation of R&D projects between government, industry and academia. Some preliminary results related to time-to-commercialization and economic competitiveness are discussed.

Precursor life science experiments and closed life support systems on the Moon

NASA Astrophysics Data System (ADS)

Rodriguez, A.; Paille, C.; Rebeyre, P.; Lamaze, B.; Lobo, M.; Lasseur, C.

Nowadays the Moon is not only a scientific exploration target but also potentially also a launch pad for deeper space exploration. Establishing an extended human presence on the Moon could reduce the cost of further space exploration, and gather the technical and scientific experience that would make possible the next steps of space exploration, namely manned-missions to Mars. To enable the establishment of such a Moon base, a reliable and regenerative life support system (LSS) is required: without any recycling of metabolic consumables (oxygen, water and food), a 6-person crew during the course of one year would require a supply of 12t from Earth (not including water for hygiene purposes), with a prohibitive associated cost! The recycling of consumables is therefore mandatory for a combination of economic, logistical and also safety reasons. Currently the main regenerative technologies used, namely water recycling in the ISS, are physical-chemical but they do not solve the issue of food production. In the European Space Agency, for the last 15 years, studies are being performed on several life support topics, namely in air revitalisation, food, water and waste management, contaminants, monitoring and control. Ground demonstration, namely the MELiSSA Pilot Plant and Concordia Station, and simulation studies demonstrated the studies feasibility and the recycling levels are promising. To be able to build LSS in a Moon base, the temperature amplitude, the dust and its 14-day night, which limits solar power supply, should be regarded. To reduce these technical difficulties, a landing site should be carefully chosen. Considering the requirements of a mission to the Moon and within the Aurora programme phase I, a preliminary configuration for a regenerative LSS can be proposed as an experiment for a precursor mission to the Moon. An overview of the necessary LSS to a Moon base will be presented, identifying Moon?s specific requirements and showing preliminary calculations. Final recommendations and considerations on the terrestrial interest of LSS technologies are done.

Towards practical time-of-flight secondary ion mass spectrometry lignocellulolytic enzyme assays

PubMed Central

2013-01-01

Background Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) is a surface sensitive mass spectrometry technique with potential strengths as a method for detecting enzymatic activity on solid materials. In particular, ToF-SIMS has been applied to detect the enzymatic degradation of woody lignocellulose. Proof-of-principle experiments previously demonstrated the detection of both lignin-degrading and cellulose-degrading enzymes on solvent-extracted hardwood and softwood. However, these preliminary experiments suffered from low sample throughput and were restricted to samples which had been solvent-extracted in order to minimize the potential for mass interferences between low molecular weight extractive compounds and polymeric lignocellulose components. Results The present work introduces a new, higher-throughput method for processing powdered wood samples for ToF-SIMS, meanwhile exploring likely sources of sample contamination. Multivariate analysis (MVA) including Principal Component Analysis (PCA) and Multivariate Curve Resolution (MCR) was regularly used to check for sample contamination as well as to detect extractives and enzyme activity. New data also demonstrates successful ToF-SIMS analysis of unextracted samples, placing an emphasis on identifying the low-mass secondary ion peaks related to extractives, revealing how extractives change previously established peak ratios used to describe enzyme activity, and elucidating peak intensity patterns for better detection of cellulase activity in the presence of extractives. The sensitivity of ToF-SIMS to a range of cellulase doses is also shown, along with preliminary experiments augmenting the cellulase cocktail with other proteins. Conclusions These new procedures increase the throughput of sample preparation for ToF-SIMS analysis of lignocellulose and expand the applications of the method to include unextracted lignocellulose. These are important steps towards the practical use of ToF-SIMS as a tool to screen for changes in plant composition, whether the transformation of the lignocellulose is achieved through enzyme application, plant mutagenesis, or other treatments. PMID:24034438

A Preliminary Investigation into Worry about Mental Health: Development of the Mental Health Anxiety Inventory.

PubMed

Commons, Della; Greenwood, Kenneth Mark; Anderson, Rebecca A

2016-05-01

Worry about physical health is broadly referred to as health anxiety and can range from mild concern to severe or persistent anxiety such as that found in DSM-IV hypochondriasis. While much is known about anxiety regarding physical health, little is known about anxiety regarding mental health. However, recent conceptualizations of health anxiety propose that individuals can experience severe and problematic worry about mental health in similar ways to how people experience extreme worry about physical health. Given the paucity of research in this area, the aim of the current study was to explore anxiety regarding mental health through validation of the Mental Health Anxiety Inventory (MHAI), a modified version of the Short Health Anxiety Inventory. The MHAI, and measures of state anxiety (Depression, Anxiety and Stress Scales-21), trait worry (Penn State Worry Questionnaire), and health anxiety (Short Health Anxiety Inventory) were administered to 104 adult volunteers from the general community. The MHAI demonstrated high internal consistency, acceptable test-retest reliability, and good construct validity when correlated with other measures of anxiety. Results also indicated that participants worried about their mental health and physical health equally, and that almost 9% of participants reported levels of mental health anxiety that were potentially problematic. Preliminary results suggest that a small proportion of adults in the community may experience high levels of mental health anxiety requiring treatment, and that the MHAI, if validated further, could be a useful tool for assessing this form of anxiety.

How Much Can We Learn from a Single Chromatographic Experiment? A Bayesian Perspective.

PubMed

Wiczling, Paweł; Kaliszan, Roman

2016-01-05

In this work, we proposed and investigated a Bayesian inference procedure to find the desired chromatographic conditions based on known analyte properties (lipophilicity, pKa, and polar surface area) using one preliminary experiment. A previously developed nonlinear mixed effect model was used to specify the prior information about a new analyte with known physicochemical properties. Further, the prior (no preliminary data) and posterior predictive distribution (prior + one experiment) were determined sequentially to search towards the desired separation. The following isocratic high-performance reversed-phase liquid chromatographic conditions were sought: (1) retention time of a single analyte within the range of 4-6 min and (2) baseline separation of two analytes with retention times within the range of 4-10 min. The empirical posterior Bayesian distribution of parameters was estimated using the "slice sampling" Markov Chain Monte Carlo (MCMC) algorithm implemented in Matlab. The simulations with artificial analytes and experimental data of ketoprofen and papaverine were used to test the proposed methodology. The simulation experiment showed that for a single and two randomly selected analytes, there is 97% and 74% probability of obtaining a successful chromatogram using none or one preliminary experiment. The desired separation for ketoprofen and papaverine was established based on a single experiment. It was confirmed that the search for a desired separation rarely requires a large number of chromatographic analyses at least for a simple optimization problem. The proposed Bayesian-based optimization scheme is a powerful method of finding a desired chromatographic separation based on a small number of preliminary experiments.

Preliminary pioneer 10 encounter results from the ames research center plasma analyzer experiment.

PubMed

Wolfe, J H; Collard, H R; Mihalov, J D; Intriligator, D S

1974-01-25

Preliminary results from the Ames Research Center plasma analyzer experiment for the Pioneer 10 Jupiter encounter indicate that Jupiter has a detached bow shock and magnetopause similar to the case at Earth but much larger in spatial extent. In contrast to Earth, Jupiter's outer magnetosphere appears to be highly inflated by thermal plasma and therefore highly responsive in size to changes in solar wind dynamic pressure.

W(h)ither the Sense of Wonder of Pre-Service Primary Teachers' when Teaching Science?: A Preliminary Study of Their Personal Experiences

ERIC Educational Resources Information Center

Stolberg, Tonie L.

2008-01-01

This preliminary study seeks to explore whether wonder-based reflections are sources of inspiration for our future teachers of science. What experiences have brought them personally a sense of wonder and when, if at all, do they employ scientific explanations of those events? In all 140 pre-service primary teachers, when questioned, described 240…

Apparatus analysis and preliminary design of low gravity porous solids experiment for STS Orbiter mid-deck

NASA Technical Reports Server (NTRS)

Fleeter, R. D.; Kropp, J. L.

1983-01-01

The apparatus analysis laboratory equipment design and fabrication and the preliminary design of the Combustion of Porous Solids Experiment for operation in the mid-deck area of the Shuttle are described. The apparatus analysis indicated that the mid-deck region of the STS was a feasible region of the Shuttle for operation. A sixteen tube concept was developed with tubes of 75 cm length and up to 5.6 cm accommodated. The experiment is viewed by IR sensors and a 16 mm camera. Laboratory equipment was designed and fabricated to test the parible injection, mixing and venting concepts. This equipment was delivered to NASA/LeRC. A preliminary design was made for the experiment based upon the apparatus analysis. The design incorporated results from the Phase ""O'' Safety Review. This design utilizes a closed tube concept in which the particles are stored, injected and burned with no coupling to the Shuttle environment. Drawings of the major components and an assembly are given. The electronics are described for the experiment. An equipment list is presented and an experiment weight estimate is determined. The mission operation requirements are outlined.

Variation in the link between parental divorce and children's health disadvantage in low and high divorce settings.

PubMed

Smith-Greenaway, Emily; Clark, Shelley

2017-12-01

Like in other world regions, children with divorced parents in sub-Saharan Africa experience significant heath disadvantages relative to their peers with married parents. Preliminary evidence suggests this disadvantage may not be uniform across the subcontinent's diverse settings. Research from other world regions shows that the childhood health consequences of divorce vary across different contexts. Specifically, we hypothesize that the childhood disadvantages associated with divorce are more severe in regions of sub-Saharan Africa where divorce is rare, and less so where divorce is a more common family experience. Using Demographic and Health Survey data from 290 subnational regions within 31 sub-Saharan African countries, multilevel models document the previously shown link between having a divorced mother and child morbidity and mortality. The study results further demonstrate that the childhood health disadvantage is accentuated in subnational African regions where fewer women are divorced and muted in areas where more women are divorced. The findings demonstrate that the broader context can powerfully moderate childhood health inequalities traditionally thought of as operating at the family or individual level.

Experimental bacteriophage treatment of honeybees (Apis mellifera) infected with Paenibacillus larvae, the causative agent of American Foulbrood Disease

PubMed Central

Yost, Diane G.; Tsourkas, Philippos; Amy, Penny S.

2016-01-01

ABSTRACT American Foulbrood Disease (AFB) is an infection of honeybees caused by the bacterium Paenibacillus larvae. One potential remedy involves using biocontrol, such as bacteriophages (phages) to lyse P. larvae. Therefore, bacteriophages specific for P. larvae were isolated to determine their efficacy in lysing P. larvae cells. Samples from soil, beehive materials, cosmetics, and lysogenized P. larvae strains were screened; of 157 total samples, 28 were positive for at least one P. larvae bacteriophage, with a total of 30. Newly isolated bacteriophages were tested for the ability to lyse each of 11 P. larvae strains. Electron microscopy demonstrated that the phage isolates were from the family Siphoviridae. Seven phages with the broadest host ranges were combined into a cocktail for use in experimental treatments of infected bee larvae; both prophylactic and post-infection treatments were conducted. Results indicated that although both pre- and post-treatments were effective, prophylactic administration of the phages increased the survival of larvae more than post-treatment experiments. These preliminary experiments demonstrate the likelihood that phage therapy could be an effective method to control AFB. PMID:27144085

Assembling a prototype resonance electrical impedance spectroscopy system for breast tissue signal detection: preliminary assessment

NASA Astrophysics Data System (ADS)

Sumkin, Jules; Zheng, Bin; Gruss, Michelle; Drescher, John; Leader, Joseph; Good, Walter; Lu, Amy; Cohen, Cathy; Shah, Ratan; Zuley, Margarita; Gur, David

2008-03-01

Using electrical impedance spectroscopy (EIS) technology to detect breast abnormalities in general and cancer in particular has been attracting research interests for decades. Large clinical tests suggest that current EIS systems can achieve high specificity (>= 90%) at a relatively low sensitivity ranging from 15% to 35%. In this study, we explore a new resonance frequency based electrical impedance spectroscopy (REIS) technology to measure breast tissue EIS signals in vivo, which aims to be more sensitive to small tissue changes. Through collaboration between our imaging research group and a commercial company, a unique prototype REIS system has been assembled and preliminary signal acquisition has commenced. This REIS system has two detection probes mounted in the two ends of a Y-shape support device with probe separation of 60 mm. During REIS measurement, one probe touches the nipple and the other touches to an outer point of the breast. The electronic system continuously generates sweeps of multi-frequency electrical pulses ranging from 100 to 4100 kHz. The maximum electric voltage and the current applied to the probes are 1.5V and 30mA, respectively. Once a "record" command is entered, multi-frequency sweeps are recorded every 12 seconds until the program receives a "stop recording" command. In our imaging center, we have collected REIS measurements from 150 women under an IRB approved protocol. The database includes 58 biopsy cases, 78 screening negative cases, and other "recalled" cases (for additional imaging procedures). We measured eight signal features from the effective REIS sweep of each breast. We applied a multi-feature based artificial neural network (ANN) to classify between "biopsy" and normal "non-biopsy" breasts. The ANN performance is evaluated using a leave-one-out validation method and ROC analysis. We conducted two experiments. The first experiment attempted to classify 58 "biopsy" breasts and 58 "non-biopsy" breasts acquired on 58 women each having one breast recommended for biopsy. The second experiment attempted to classify 58 "biopsy" breasts and 58 negative breasts from the set of screening negative cases. The areas under ROC curves are 0.679 +/- 0.033 and 0.606 +/- 0.035 for the first and the second experiment, respectively. The preliminary results demonstrate (1) even with this rudimentary system with only one paired probes there is a measurable signal of changes in breast tissue demonstrating the feasibility of applying REIS technology for identifying at least some women with highly suspicious breast abnormalities and (2) the electromagnetic asymmetry between two breasts may be more sensitive in detecting changes in the abnormal breast. To further improve the REIS system performance, we are currently designing a new REIS system with multiple electrical probes and a more sophisticated analysis scheme.

Skylab 3 and 4 science demonstrations: Preliminary report

NASA Technical Reports Server (NTRS)

Bannister, T. C.

1974-01-01

Twelve science demonstrations were accomplished on the Skylab 3 and 4 missions. These were defined in response to crew requests for time-gap fillers and were designed to be accomplished using onboard equipment. The following 12 are described and the preliminary results are given: liquid floating zone; diffusion in liquids; ice melting; immiscible liquids; liquid films; gyroscope; Rochelle salt growth; deposition of silver crystals; fluid mechanics series; neutron environment; orbital mechanics; and charged particle mobility.

Cherenkov light identification in TeO2 crystals with Si low-temperature detectors

NASA Astrophysics Data System (ADS)

Gironi, L.; Biassoni, M.; Brofferio, C.; Capelli, S.; Carniti, P.; Cassina, L.; Clemenza, M.; Cremonesi, O.; Faverzani, M.; Ferri, E.; Giachero, A.; Gotti, C.; Maino, M.; Margesin, B.; Nucciotti, A.; Pavan, M.; Pessina, G.; Pozzi, S.; Previtali, E.; Puiu, A.; Sisti, M.; Terranova, F.

2017-09-01

Low temperature thermal detectors with particle identification capabilities are among the best detectors for next generation experiments for the search of neutrinoless double beta decay. Thermal detectors allow to reach excellent energy resolution and to optimize the detection efficiency, while the possibility to identify the interacting particle allows to greatly reduce the background. Tellurium dioxide is one of the favourite compounds since it has long demonstrated the first two features and could reach the third through Cherenkov emission tagging [1]. A new generation of cryogenic light detectors are however required to detect the few Cherenkov photons emitted by electrons of few MeV energy. Preliminary measurements with new Si light detectors demonstrated a clear event-by-event discrimination between alpha and beta/gamma interactions at the 130Te neutrinoless double beta decay Q-value (2528 keV).

Field Testing of a Two-Micron DIAL System for Profiling Atmospheric Carbon Dioxide

NASA Technical Reports Server (NTRS)

Refaat, Tamer F.; Ismail, Syed; Koch, Grady J.; Diaz, Liza; Davis, Ken; Rubio, Manuel

2010-01-01

A 2-m DIAL system has been developed at NASA Langley Research Center through the NASA Instrument Incubator Program. The system utilizes a tunable 2-m pulsed laser and an IR phototransistor for the transmitter and the receiver, respectively. The system targets the CO2 absorption line R22 in the 2.05-m band. Field experiments were conducted at West Branch, Iowa, for evaluating the system for CO2 measurement by comparison with in-situ sensors. The CO2 in-situ sensors were located on the NOAA's WBI tower at 31, 99 and 379 m altitudes, besides the NOAA s aircraft was sampling at higher altitudes. Preliminary results demonstrated the capabilities of the DIAL system in profiling atmospheric CO2 using the 2-m wavelength. Results of these experiments will be presented and discussed.

Solar thermal storage applications program

NASA Astrophysics Data System (ADS)

Peila, W. C.

1982-12-01

The efforts of the Storage Applications Program are reviewed. The program concentrated on the investigation of storage media and evaluation of storage methods. Extensive effort was given to experimental and analytical investigations of nitrate salts. Two tasks are the preliminary design of a 1200 MW/sub th/ system and the design, construction, operation, and evaluation of a subsystem research experiment, which utilized the same design. Some preliminary conclusions drawn from the subsystem research experiment are given.

Shallow Water Acoustic Experiments and Preliminary Planning for FY06 Fieldwork

DTIC Science & Technology

2011-03-21

To) 5/1/2005-12/31/2010 4. TITLE AND SUBTITLE Shallow Water Acoustic Experiments and Preliminary Planning for FY06 Fieldwork 5a. CONTRACT NUMBERS...numerical computations show horizontal interference patterns within the duct. Richly de - tailed sound radiation fields are predicted at locations far...4) for the vertical modal amplitude Tm at x^L is now de - scribed in detail. First, the assumption of total transmission at the open-ended

A 100 kW-Class Technology Demonstrator for Space Solar Power

NASA Technical Reports Server (NTRS)

Carrington, Connie; Howell, Joe; Day, Greg

2004-01-01

A first step in the development of solar power from space is the flight demonstration of critical technologies. These fundamental technologies include efficient solar power collection and generation, power management and distribution, and thermal management. In addition, the integration and utilization of these technologies into a viable satellite bus could provide an energy-rich platform for a portfolio of payload experiments such as wireless power transmission (WPT). This paper presents the preliminary design of a concept for a 100 kW-class fiee-flying platform suitable for flight demonstration of technology experiments. Recent space solar power (SSP) studies by NASA have taken a stepping stones approach that lead to the gigawatt systems necessary to cost-effectively deliver power from space. These steps start with a 100 kW-class satellite, leading to a 500 kW and then a 1 MW-class platform. Later steps develop a 100 M W bus that could eventually lead to a 1-2 GW pilot plant for SSP. Our studies have shown that a modular approach is cost effective. Modular designs include individual laser-power-beaming satellites that fly in constellations or that are autonomously assembled into larger structures at geosynchronous orbit (GEO). Microwave power-beamed approaches are also modularized into large numbers of identical units of solar arrays, power converters, or supporting structures for arrays and microwave transmitting antennas. A cost-effective approach to launching these modular units is to use existing Earth-to-orbit (ETO) launch systems, in which the modules are dropped into low Earth orbit (LEO) and then the modules perform their own orbit transfer to GEO using expendable solar arrays to power solar electric thrusters. At GEO, the modules either rendezvous and are assembled robotically into larger platforms, or are deployed into constellations of identical laser power-beaming satellites. Since solar electric propulsion by the modules is cost-effective for both self-transport of the modules from LEO to GEO, and for on-orbit stationkeeping and repositioning capability during the satellite's lifetime, this technology is also critical in technology development for SSP. The 100 kW-class technology demonstrator will utilize advanced solar power collection and generation technologies, power management and distribution, advanced thermal management, and solar electric propulsion. State-of-the-art solar concentrators, highly efficient multi-junction solar cells, integrated thermal management on the arrays, and innovative deployable structure design and packaging make the 100 kW satellite feasible for launch on one existing launch vehicle. Early SSP studies showed that a major percentage of the on-orbit mass for power-beaming satellites was from massive power converters at the solar arrays, at the bus, at the power transmitter, or at combinations of these locations. Higher voltage mays and power management and distribution (PMAD) systems reduce or eliminate the need for many of these massive power converters, and could enable direct-drive of high-voltage solar electric thrusters. Lightweight, highly efficient thermal management systems are a critical technology that must be developed and flown for SSP feasibility. Large amounts of power on satellites imply that large amounts of waste heat will need to be managed. In addition, several of the more innovative lightweight configurations proposed for SSP satellites take advantage of solar concentrators that are intractable without advanced thermal management technologies for the solar arrays. These thermal management systems include efficient interfaces with the WPT systems or other high-power technology experiments, lightweight deployable radiators that can be easily integrated into satellite buses, and efficient reliable thermal distribution systems that can pipe heat from the technology experiments to the radiators. In addition to demonstrating the integration and use of these mission-ctical technologies, the 100 kw-class satellite will provide a large experiment deck for a portfolio of technology experiments. Current plans for this technology demonstrator allow 2000 kg of payload capability and up to 100 kW of power. The technology experiments could include one or more wireless power transmission demonstrations, either to the Earth s surface or to a suitable space-based receiver. Technology experiments to quantify the on-orbit performance of critical technologies for SSP or space exploration are welcomed. In addition, the technology experiments provide an opportunity for international cooperation, to advance technology readiness levels of SSP technologies that require flight demonstration. This paper will present the preliminary design for a 100 kW solar-powered satellite and a variety of technology experiments that may be suitable for flight demonstration. In addition, a space-to-Earth-surface WPT experiment will be discussed.

Preliminary analyses of WL experiment No. 701, space environment effects on operating fiber optic systems

NASA Technical Reports Server (NTRS)

Taylor, E. W.; Berry, J. N.; Sanchez, A. D.; Padden, R. J.; Chapman, S. P.

1992-01-01

A brief overview of the analyses performed to date on WL Experiment-701 is presented. Four active digital fiber optic links were directly exposed to the space environment for a period of 2114 days. The links were situated aboard the Long Duration Exposure Facility (LDEF) with the cabled, single fiber windings atop an experimental tray containing instrumentation for exercising the experiment in orbit. Despite the unplanned and prolonged exposure to trapped and galactic radiation, wide temperature extremes, atomic oxygen interactions, and micro-meteorite and debris impacts, in most instances the optical data links performed well within the experimental limits. Analysis of the recorded orbital data clearly indicates that fiber optic applications in space will meet with success. Ongoing tests and analysis of the experiment at the Phillips Laboratory's Optoelectronics Laboratory will expand this premise, and establish the first known and extensive database of active fiber optic link performance during prolonged space exposure. WL Exp-701 was designed as a feasibility demonstration for fiber optic technology in space applications, and to study the performance of operating fiber systems exposed to space environmental factors such as galactic radiation, and wide temperature cycling. WL Exp-701 is widely acknowledged as a benchmark accomplishment that clearly demonstrates, for the first time, that fiber optic technology can be successfully used in a variety of space applications.

Preliminary Findings from the SHERE ISS Experiment

NASA Technical Reports Server (NTRS)

Hall, Nancy R.; McKinley, Gareth H.; Erni, Philipp; Soulages, Johannes; Magee, Kevin S.

2009-01-01

The Shear History Extensional Rheology Experiment (SHERE) is an International Space Station (ISS) glovebox experiment designed to study the effect of preshear on the transient evolution of the microstructure and viscoelastic tensile stresses for monodisperse dilute polymer solutions. The SHERE experiment hardware was launched on Shuttle Mission STS-120 (ISS Flight 10A) on October 22, 2007, and 20 fluid samples were launched on Shuttle Mission STS-123 (ISS Flight 10/A) on March 11, 2008. Astronaut Gregory Chamitoff performed experiments during Increment 17 on the ISS between June and September 2008. A summary of the ten year history of the hardware development, the experiment's science objectives, and Increment 17's flight operations are discussed in the paper. A brief summary of the preliminary science results is also discussed.

A frequency standard via spectrum analysis and direct digital synthesis

NASA Astrophysics Data System (ADS)

Li, Dawei; Shi, Daiting; Hu, Ermeng; Wang, Yigen; Tian, Lu; Zhao, Jianye; Wang, Zhong

2014-11-01

We demonstrated a frequency standard based on a detuned coherent population beating phenomenon. In this phenomenon, the beat frequency of the radio frequency for laser modulation and the hyperfine splitting can be obtained by digital signal processing technology. After analyzing the spectrum of the beat frequency, the fluctuation information is obtained and applied to compensate for the frequency shift to generate the standard frequency by the digital synthesis method. Frequency instability of 2.6 × 1012 at 1000 s is observed in our preliminary experiment. By eliminating the phase-locking loop, the method will enable us to achieve a full-digital frequency standard with remarkable stability.

Development of an intelligent hypertext system for wind tunnel testing

NASA Technical Reports Server (NTRS)

Lo, Ching F.; Shi, George Z.; Steinle, Frank W.; Wu, Y. C. L. Susan; Hoyt, W. Andes

1991-01-01

This paper summarizes the results of a system utilizing artificial intelligence technology to improve the productivity of project engineers who conduct wind tunnel tests. The objective was to create an intelligent hypertext system which integrates a hypertext manual and expert system that stores experts' knowledge and experience. The preliminary (Phase I) effort implemented a prototype IHS module encompassing a portion of the manuals and knowledge used for wind tunnel testing. The effort successfully demonstrated the feasibility of the intelligent hypertext system concept. A module for the internal strain gage balance, implemented on both IBM-PC and Macintosh computers, is presented. A description of the Phase II effort is included.

A Module Experimental Process System Development Unit (MEPSDU). [development of low cost solar arrays

NASA Technical Reports Server (NTRS)

1981-01-01

The technical readiness of a cost effective process sequence that has the potential for the production of flat plate photovoltaic modules which met the price goal in 1986 of $.70 or less per Watt peak was demonstrated. The proposed process sequence was reviewed and laboratory verification experiments were conducted. The preliminary process includes the following features: semicrystalline silicon (10 cm by 10 cm) as the silicon input material; spray on dopant diffusion source; Al paste BSF formation; spray on AR coating; electroless Ni plate solder dip metallization; laser scribe edges; K & S tabbing and stringing machine; and laminated EVA modules.

Practical in-situ determination of ortho-para hydrogen ratios via fiber-optic based Raman spectroscopy

DOE PAGES

Sutherland, Liese -Marie; Knudson, James N.; Mocko, Michal; ...

2015-12-17

An experiment was designed and developed to prototype a fiber-optic-based laser system, which measures the ratio of ortho-hydrogen to para-hydrogen in an operating neutron moderator system at the Los Alamos Neutron Science Center (LANSCE) spallation neutron source. Preliminary measurements resulted in an ortho to para ratio of 3.06:1, which is within acceptable agreement with the previously published ratio. As a result, the successful demonstration of Raman Spectroscopy for this measurement is expected to lead to a practical method that can be applied for similar in-situ measurements at operating neutron spallation sources.

Practical in-situ determination of ortho-para hydrogen ratios via fiber-optic based Raman spectroscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sutherland, Liese -Marie; Knudson, James N.; Mocko, Michal

An experiment was designed and developed to prototype a fiber-optic-based laser system, which measures the ratio of ortho-hydrogen to para-hydrogen in an operating neutron moderator system at the Los Alamos Neutron Science Center (LANSCE) spallation neutron source. Preliminary measurements resulted in an ortho to para ratio of 3.06:1, which is within acceptable agreement with the previously published ratio. As a result, the successful demonstration of Raman Spectroscopy for this measurement is expected to lead to a practical method that can be applied for similar in-situ measurements at operating neutron spallation sources.

Narrative Exposure Therapy: A Proposed Model to Address Intimate Partner Violence-Related PTSD in Parenting and Pregnant Adolescents.

PubMed

Volpe, Ellen M; Quinn, Camille R; Resch, Kathryn; Sommers, Marilyn S; Wieling, Elizabeth; Cerulli, Catherine

Pregnant and parenting adolescents experience high rates of intimate partner violence (IPV) and its sequelae posttraumatic stress disorder (PTSD) and depression. Narrative exposure therapy (NET) is an innovative intervention that has demonstrated strong preliminary evidence in improving mental health. The specific aims of this article are 3-fold: (1) provide a brief background about IPV-related PTSD and depression among pregnant and parenting adolescents; (2) describe NET's theoretical principles, its therapeutic process, and provide a review of existing evidence; and (3) discuss NET as a potential treatment to address the mental health burden among adolescents experiencing IPV-related PTSD and depression.

Process material management in the Space Station environment

NASA Technical Reports Server (NTRS)

Perry, J. L.; Humphries, W. R.

1988-01-01

The Space Station will provide a unique facility for conducting material-processing and life-science experiments under microgravity conditions. These conditions place special requirements on the U.S. Laboratory for storing and transporting chemicals and process fluids, reclaiming water from selected experiments, treating and storing experiment wastes, and providing vacuum utilities. To meet these needs and provide a safe laboratory environment, the Process Material Management System (PMMS) is being developed. Preliminary design requirements and concepts related to the PMMS are addressed, and the MSFC PMMS breadboard test facility and a preliminary plan for validating the overall system design are discussed.

Preliminary investigations of protein crystal growth using the Space Shuttle

NASA Technical Reports Server (NTRS)

Delucas, L. J.; Suddath, F. L.; Snyder, R.; Naumann, R.; Broom, M. B.; Pusey, M.; Yost, V.; Herren, B .; Carter, D.

1986-01-01

Four preliminary Shuttle experiments are described which have been used to develop prototype hardware for a more advanced system that will evaluate effects of gravity on protein crystal growth. The first phase of these experiments has centered on the development of micromethods for protein crystal growth by vapor-diffusion techniques (using a space version of the hanging-drop method) and on dialysis using microdialysis cells. Results suggest that the elimination of density-driven sedimentation can effect crystal morphology. In the dialysis experiment, space-grown crystals of concanavalin B were three times longer and 1/3 the thickness of earth-grown crystals.

Fiscal year 1981 US corn and soybeans pilot preliminary experiment plan, phase 1

NASA Technical Reports Server (NTRS)

Livingston, G. P.; Nedelman, K. S.; Norwood, D. F.; Smith, J. H. (Principal Investigator)

1981-01-01

A draft of the preliminary experiment plan for the foreign commodity production forecasting project fiscal year 1981 is presented. This draft plan includes: definition of the phase 1 and 2 U.S. pilot objectives; the proposed experiment design to evaluate crop calendar, area estimation, and area aggregation components for corn and soybean technologies using 1978/1979 crop-year data; a description of individual sensitivity evaluations of the baseline corn and soybean segment classification procedure; and technology and data assessment in support of the corn and soybean estimation technology for use in the U.S. central corn belt.

Preliminary technical results review of FY81 experiments. Volume 1: Fiscal year 1981/82 spring small grains pilot experiment. [Canada and the United States

NASA Technical Reports Server (NTRS)

1981-01-01

Technical progress made in the foreign commodity production forecasting for the advancement of spring small grains (SSG) area estimation is reported with emphasis on results achieved since the last AgRISTARS level semiannual review. Major objectives and accomplishments are reviewed and the experiment is described. The technical approach data assessment, and data systems used are considered. Results of the group approach comparison study are presented along with preliminary aggregation results for SSG processing procedures. The outlook for the future is assessed.

Cryogenic Technology Development for Exploration Missions

NASA Technical Reports Server (NTRS)

Chato, David J.

2007-01-01

This paper reports the status and findings of different cryogenic technology research projects in support of the President s Vision for Space Exploration. The exploration systems architecture study is reviewed for cryogenic fluid management needs. It is shown that the exploration architecture is reliant on the cryogenic propellants of liquid hydrogen, liquid oxygen and liquid methane. Needs identified include: the key technologies of liquid acquisition devices, passive thermal and pressure control, low gravity mass gauging, prototype pressure vessel demonstration, active thermal control; as well as feed system testing, and Cryogenic Fluid Management integrated system demonstration. Then five NASA technology projects are reviewed to show how these needs are being addressed by technology research. Projects reviewed include: In-Space Cryogenic Propellant Depot; Experimentation for the Maturation of Deep Space Cryogenic Refueling Technology; Cryogenic Propellant Operations Demonstrator; Zero Boil-Off Technology Experiment; and Propulsion and Cryogenic Advanced Development. Advances are found in the areas of liquid acquisition of liquid oxygen, mass gauging of liquid oxygen via radio frequency techniques, computational modeling of thermal and pressure control, broad area cooling thermal control strategies, flight experiments for resolving low gravity issues of cryogenic fluid management. Promising results are also seen for Joule-Thomson pressure control devices in liquid oxygen and liquid methane and liquid acquisition of methane, although these findings are still preliminary.

Preadaptation to the stimulus rearrangement of weightlessness: Preliminary studies and concepts for trainer designs

NASA Technical Reports Server (NTRS)

Parker, D. E.; Reschke, M. F.

1988-01-01

An effort to develop preflight adaptation training (PAT) apparatus and procedures to adapt astronauts to the stimulus rearrangement of weightless spaceflight is being pursued. Based on the otolith tilt-translation reinterpretation model of sensory adaptation to weightlessness, two prototype preflight adaptation trainers (PAT) have been developed. These trainers couple pitch movement of the subject with translation of the visual surround. Subjects were exposed to this stimulus rearrangement for periods of 30 m. The hypothesis is that exposure to the rearrangement would attenuate vertical eye movements was supported by two experiments using the Miami University Seesaw (MUS) PAT prototype. The Dynamic Environment Simulator (DES) prototype failed to support this hypothesis; this result is attributed to a pecularity of the DES apparatus. A final experiment demonstrated that changes in vertical eye movements were not a consequence of fixation on an external target during exposure to a control condition. Together these experiments support the view that preflight adaptation training can alter eye movements in a manner consistent with adaptation to weightlessness. Following these initial studies, concepts for development of operational preflight trainers were proposed. The trainers are intended to: demonstrate the stimulus rearrangement of weightlessness; allow astronauts to train in altered sensory environment; modify sensory motor reflexes; and reduce/eliminate space motion sickness symptoms.

Proof of concept demonstration of novel technologies for lunar spacesuit dust mitigation

NASA Astrophysics Data System (ADS)

Manyapu, Kavya K.; De Leon, Pablo; Peltz, Leora; Gaier, James R.; Waters, Deborah

2017-08-01

A recent report by NASA identified dust/particulate mitigation techniques as a highly relevant study for future long-term planetary exploration missions (NASA, 2015). The deleterious effects of lunar dust on spacesuits discovered during the Apollo missions has compelled NASA to identify dust mitigation as a critical path for potential future lunar, asteroid and Mars missions. The complexity of spacesuit design has however constrained integrating existing dust cleaning technologies, formerly demonstrated on rigid surfaces, into the spacesuit system. Accordingly, this research is investigating novel methods to integrate dust mitigation technologies for use on spacesuits. We examine utilizing a novel combination of active and passive technologies integrated into the spacesuit outerlayer to alleviate dust contamination. Leveraging two specific technologies, the Electrodynamics Dust Shield (EDS) active technology and Work Function Matching Coating (WFM) passive technology, developed by NASA for rigid surfaces, we apply new high performance materials such as the Carbon Nanotube (CNT) flexible fibers to develop a spacesuit-integrated dust cleaning system. Through experiments conducted using JSC-1A lunar dust simulant on coupons made of spacesuit outerlayer material, feasibility of integrating the proposed dust cleaning system and its performance were assessed. Results from these preliminary experiments show that the integrated dust cleaning system is capable of removing 80-95% of dust from the spacesuit material demonstrating proof of concept. This paper describes the techniques and results from the experiments. Future challenges of implementing the proposed approach into fight suits are identified.

Burst annealing of high temperature GaAs solar cells

NASA Technical Reports Server (NTRS)

Brothers, P. R.; Horne, W. E.

1991-01-01

One of the major limitations of solar cells in space power systems is their vulnerability to radiation damage. One solution to this problem is to periodically heat the cells to anneal the radiation damage. Annealing was demonstrated with silicon cells. The obstacle to annealing of GaAs cells was their susceptibility to thermal damage at the temperatures required to completely anneal the radiation damage. GaAs cells with high temperature contacts and encapsulation were developed. The cells tested are designed for concentrator use at 30 suns AMO. The circular active area is 2.5 mm in diameter for an area of 0.05 sq cm. Typical one sun AMO efficiency of these cells is over 18 percent. The cells were demonstrated to be resistant to damage after thermal excursions in excess of 600 C. This high temperature tolerance should allow these cells to survive the annealing of radiation damage. A limited set of experiments were devised to investigate the feasibility of annealing these high temperature cells. The effect of repeated cycles of electron and proton irradiation was tested. The damage mechanisms were analyzed. Limitations in annealing recovery suggested improvements in cell design for more complete recovery. These preliminary experiments also indicate the need for further study to isolate damage mechanisms. The primary objective of the experiments was to demonstrate and quantify the annealing behavior of high temperature GaAs cells. Secondary objectives were to measure the radiation degradation and to determine the effect of repeated irradiation and anneal cycles.

Orientation in birds. The sun compass.

PubMed

Schmidt-Koenig, K; Ganzhorn, J U; Ranvaud, R

1991-01-01

The sun compass was discovered by G. Kramer in caged birds showing migratory restlessness. Subsequent experiments with caged birds employing directional training and clock shifts, carried out by Hoffman and Schmidt-Koenig, showed that the sun azimuth is used, and the sun altitude ignored. In the laboratory, McDonald found the accuracy to be +/- 3 degrees(-)+/- 5 degrees. According to Hoffmann and Schmidt-Koenig, caged birds trained at medium northern latitudes were able to allow for the sun's apparent movement north of the arctic circle, but not in equatorial and trans-equatorial latitudes. In homing experiments, and employing clock shifts, Schmidt-Koenig demonstrated that the sun compass is used by homing pigeons during initial orientation. This finding is the principal evidence for the existence of a map-and-compass navigational system. Pigeons living in equatorial latitudes utilize the sun compass even under the extreme solar conditions of equinox, achieving angular resolution of about 3 degrees in homing experiments. According to preliminary analyses, the homing pigeons' ephemerides are retarded by several weeks (Ranvaud, Schmidt-Koenig, Ganzhorn et al.).

Gravity anomaly detection: Apollo/Soyuz

NASA Technical Reports Server (NTRS)

Vonbun, F. O.; Kahn, W. D.; Bryan, J. W.; Schmid, P. E.; Wells, W. T.; Conrad, D. T.

1976-01-01

The Goddard Apollo-Soyuz Geodynamics Experiment is described. It was performed to demonstrate the feasibility of tracking and recovering high frequency components of the earth's gravity field by utilizing a synchronous orbiting tracking station such as ATS-6. Gravity anomalies of 5 MGLS or larger having wavelengths of 300 to 1000 kilometers on the earth's surface are important for geologic studies of the upper layers of the earth's crust. Short wavelength Earth's gravity anomalies were detected from space. Two prime areas of data collection were selected for the experiment: (1) the center of the African continent and (2) the Indian Ocean Depression centered at 5% north latitude and 75% east longitude. Preliminary results show that the detectability objective of the experiment was met in both areas as well as at several additional anomalous areas around the globe. Gravity anomalies of the Karakoram and Himalayan mountain ranges, ocean trenches, as well as the Diamantina Depth, can be seen. Maps outlining the anomalies discovered are shown.

Microsurgical robotic system for the deep surgical field: development of a prototype and feasibility studies in animal and cadaveric models.

PubMed

Morita, Akio; Sora, Shigeo; Mitsuishi, Mamoru; Warisawa, Shinichi; Suruman, Katopo; Asai, Daisuke; Arata, Junpei; Baba, Shoichi; Takahashi, Hidechika; Mochizuki, Ryo; Kirino, Takaaki

2005-08-01

To enhance the surgeon's dexterity and maneuverability in the deep surgical field, the authors developed a master-slave microsurgical robotic system. This concept and the results of preliminary experiments are reported in this paper. The system has a master control unit, which conveys motion commands in six degrees of freedom (X, Y, and Z directions; rotation; tip flexion; and grasping) to two arms. The slave manipulator has a hanging base with an additional six degrees of freedom; it holds a motorized operating unit with two manipulators (5 mm in diameter, 18 cm in length). The accuracy of the prototype in both shallow and deep surgical fields was compared with routine freehand microsurgery. Closure of a partial arteriotomy and complete end-to-end anastomosis of the carotid artery (CA) in the deep operative field were performed in 20 Wistar rats. Three routine surgical procedures were also performed in cadavers. The accuracy of pointing with the nondominant hand in the deep surgical field was significantly improved through the use of robotics. The authors successfully closed the partial arteriotomy and completely anastomosed the rat CAs in the deep surgical field. The time needed for stitching was significantly shortened over the course of the first 10 rat experiments. The robotic instruments also moved satisfactorily in cadavers, but the manipulators still need to be smaller to fit into the narrow intracranial space. Computer-controlled surgical manipulation will be an important tool for neurosurgery, and preliminary experiments involving this robotic system demonstrate its promising maneuverability.

Dating ancient mosaic glasses by luminescence: The case study of San Pietro in Vaticano

NASA Astrophysics Data System (ADS)

Galli, A.; Martini, M.; Sibilia, E.; Vandini, M.; Villa, I.

2011-12-01

The preliminary results of a study on the dosimetric properties of a set of glass tesserae from the mosaics of the vaults of St. Peter's Basilica in Rome (late XVI century) are reported. The main goal of the research was to assess the possibility of dating them by means of luminescence techniques. The samples had already been extensively studied and investigated from a historical, artistic and compositional point of view. The period of the making of the mosaic was rather well known, and could be the basis to test the experimental procedures we used for dosimetry. The experiments also aimed at demonstrating the validity of the hypothesis we put forward, i.e. the positive link between the presence of micro-crystals and the luminescence sensitivity in mosaic glass: to this aim, the samples richer in crystalline inclusions were selected. The role of calcium antimonate and cassiterite was definitely demonstrated. For what concerns their thermoluminescence (TL) characteristics, a preliminary investigation suggested that the available configuration of the detection systems did not properly fit the wavelength of the emitted TL. Much more promising results have been achieved by the use of Optically Stimulated Luminescence (OSL), even if the measured absorbed doses were rather scattered. For one sample with high OSL sensitivity, it was possible to establish its recent age, relative to one of the documented restorations that took place during the last century.

Preliminary experience of shared clinical management between Milan and Pointe Noire using the INteractive TeleConsultation Network for Worldwide HealthcAre Services (INCAS): telemedicine between Milan and Africa.

PubMed

Malacarne, Mara; Lesma, Alessandro; Madera, Angelo; Malfatti, Eugenio; Castelli, Alberto; Lucini, Daniela; Pizzinelli, Paolo; Pagani, Massimo

2004-01-01

This paper describes preliminary experience in shared clinical management of patients located in Pointe Noire, Africa, and a referral center, Sacco University Hospital, located in Milan, Italy. The employed infrastructure INteractive TeleConsultation Network for Worldwide HealthcAre Services (INCAS) jointly developed by CEFRIEL (Center of Excellence For Research, Innovation, Education & Industrial Labs partnership) and ENI (Ente Nazionale Idrocarburi) is based on commercial off-the-shelf technology. This minimizes maintenance problems, while permitting a simple and friendly sharing of data using the telephone and e-mail for store-and-forward applications. The critical aspect of the flow of events comprising the exchange of information is discussed. In 60% of cases, only one telemedicine consultation was required. In the remainder 40%, a number of telemedicine consultations were required for appropriate management of clinical cases. The project demonstrated flexibility as documented by the wide range of pathologies that can be dealt with it. Finally the possibility of using shared clinical management as a learning tool is highlighted by the steep and rising learning curve. We conclude, however, that the patient, although handled in a "virtual" manner, should be viewed as very "real," as some of them elected to close the gap physically between Pointe Noire and Milan, and chose to be treated at the referral site.

Evidence for S-adenosyl-L-methionine (SAM-e) for the treatment of major depressive disorder.

PubMed

Papakostas, George I

2009-01-01

Despite the increasingly large array of antidepressants available to treat major depressive disorder, patients continue to experience relatively modest response and remission rates. In addition, patients may experience adverse side effects from pharmacotherapy that not only hinder treatment compliance and adherence but, in some cases, may also contribute to increased disability, patient suffering, morbidity, and mortality. In order to enhance treatment efficacy and tolerability, patients and clinicians have become increasingly interested in nonpharmaceutical supplements for treating depression. One of the best-studied of these supplements is S-adenosyl-L-methionine (SAM-e), a naturally occurring molecule present in all living cells and a major methyl group donor in the human body. Controlled trials have found SAM-e to be more efficacious than placebo and equal in efficacy to the tricyclic antidepressants for treating major depressive disorder (MDD) when administered parenterally (either intravenously or intramuscularly). Less evidence supports the use of oral SAM-e, although some trials have demonstrated its efficacy as well. In addition, there is a paucity of evidence examining whether oral forms of SAM-e can be safe, well tolerated, and efficacious when used as adjunctive treatment for antidepressant nonresponders with MDD. Although preliminary data suggest SAM-e may be useful as an adjunctive therapy to antidepressants, controlled studies are needed to confirm or refute these preliminary findings. (c) Copyright 2009 Physicians Postgraduate Press, Inc.

A Novel Acousto-Electric Levitator for Studies of Drop and Particle Clusters and Arrays

NASA Technical Reports Server (NTRS)

Tian, Yuren; Apfel, Robert E.; Zheng, Yibing

1999-01-01

A novel and compact instrumentation for studying the behavior of drop sprays and of clusters of drops now permits fundamental research into the behavior of reacting and non-reacting fluid and solid species. The new capability is made possible by simultaneous acousto-electric levitation and charging of "seed" droplets (10-30 microns in diameter) which come together in 2-D clusters (with up to 300 droplets). These clusters are interesting in their own right because of their crystalline and quasi-crystalline forms, which depend on the acoustic and electric field parameters. By varying the electric and acoustic field intensities, one can cause a cluster of droplets to condense into larger drops (e.g. 50-300 microns) which, because of their charge, form uniformly spaced 2-D arrays of monodispersed drops (e.g. 30-40 array drops in preliminary experiments). One or more layers of these 2-D arrays can form in the acoustic standing wave. Such a configuration permits a wide range of fundamental studies of drop evaporation, combustion, and nucleation. The drops can be single or multicomponent. Therefore, fundamental materials studies can also be performed. Using this same Cluster and Array Generation (CAG) instrumentation, it has been also possible in preliminary experiments to demonstrate the clustering and arraying of solid particles, both coated with an electrically conducting layer and uncoated, and both charged and uncharged.

Investigating the effect of peptide agonists on the chondrogenic differentiation of human mesenchymal stem cells using design of experiments.

PubMed

Renner, Julie N; Liu, Julie C

2013-01-01

Human mesenchymal stem cells (MSCs) are attractive for use in cartilage tissue engineering. Cells are often seeded in a structural scaffold containing growth factors. Peptide mimics of full-length growth factors are a promising alternative because they are less expensive and easier to manufacture. We investigated four short peptides for their effect on the chondrogenesis of human MSCs. The peptides were originally designed to mimic bone morphogenetic protein-2 (BMP-2), transforming growth factor-beta 1 (TGF-β1), and insulin, all of which have been shown to affect MSC chondrogenesis. Previous studies demonstrated that the peptides elicited bioactivity in other cell types, but the peptides have not been investigated for their effect on chondrogenesis in human MSCs. In a preliminary investigation, peptides were added to a pellet culture of human MSCs and assayed for their effect on glycosaminoglycan (GAG) production. These experiments determined peptide concentrations used in a full-factorial experiment to investigate any interactions. The experiment revealed the BMP peptide as a robust stimulant for GAG production. . © 2013 American Institute of Chemical Engineers.

MODELING AND ANALYSIS OF FISSION PRODUCT TRANSPORT IN THE AGR-3/4 EXPERIMENT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Humrickhouse, Paul W.; Collin, Blaise P.; Hawkes, Grant L.

In this work we describe the ongoing modeling and analysis efforts in support of the AGR-3/4 experiment. AGR-3/4 is intended to provide data to assess fission product retention and transport (e.g., diffusion coefficients) in fuel matrix and graphite materials. We describe a set of pre-test predictions that incorporate the results of detailed thermal and fission product release models into a coupled 1D radial diffusion model of the experiment, using diffusion coefficients reported in the literature for Ag, Cs, and Sr. We make some comparisons of the predicted Cs profiles to preliminary measured data for Cs and find these to bemore » reasonable, in most cases within an order of magnitude. Our ultimate objective is to refine the diffusion coefficients using AGR-3/4 data, so we identify an analytical method for doing so and demonstrate its efficacy via a series of numerical experiments using the model predictions. Finally, we discuss development of a post-irradiation examination plan informed by the modeling effort and simulate some of the heating tests that are tentatively planned.« less

Mini-DIAL system measurements coupled with multivariate data analysis to identify TIC and TIM simulants: preliminary absorption database analysis.

NASA Astrophysics Data System (ADS)

Gaudio, P.; Malizia, A.; Gelfusa, M.; Martinelli, E.; Di Natale, C.; Poggi, L. A.; Bellecci, C.

2017-01-01

Nowadays Toxic Industrial Components (TICs) and Toxic Industrial Materials (TIMs) are one of the most dangerous and diffuse vehicle of contamination in urban and industrial areas. The academic world together with the industrial and military one are working on innovative solutions to monitor the diffusion in atmosphere of such pollutants. In this phase the most common commercial sensors are based on “point detection” technology but it is clear that such instruments cannot satisfy the needs of the smart cities. The new challenge is developing stand-off systems to continuously monitor the atmosphere. Quantum Electronics and Plasma Physics (QEP) research group has a long experience in laser system development and has built two demonstrators based on DIAL (Differential Absorption of Light) technology could be able to identify chemical agents in atmosphere. In this work the authors will present one of those DIAL system, the miniaturized one, together with the preliminary results of an experimental campaign conducted on TICs and TIMs simulants in cell with aim of use the absorption database for the further atmospheric an analysis using the same DIAL system. The experimental results are analysed with standard multivariate data analysis technique as Principal Component Analysis (PCA) to develop a classification model aimed at identifying organic chemical compound in atmosphere. The preliminary results of absorption coefficients of some chemical compound are shown together pre PCA analysis.

Results of the 1998 Field Demonstration and Preliminary Implementation Guidance for Phytoremediation of Lead-Contaminated Soil at the Twin Cities Army Ammunition Plant, Arden Hills, Minnesota

DTIC Science & Technology

1999-03-01

Results of the 1998 Field Demonstration and Preliminary Implementation Guidance for Phytoremediation of Lead-Contaminated Soil at the Twin... Phytoremediation of Lead-Contaminated Soil at the Twin Cities Army Ammunition Plant, Arden Hills, Minnesota. 12. PERSONAL AUTHOR(S) A. P. Behel, Jr...CODES FIELD GROUP SUB-GROUP 18. SUBJECT TERMS (Continue on reverse if necessary and identify by block number) Phytoremediation of Lead-Contaminated

Preliminary measurements of the edge magnetic field pitch from 2-D Doppler backscattering in MAST and NSTX-U (invited)

NASA Astrophysics Data System (ADS)

Vann, R. G. L.; Brunner, K. J.; Ellis, R.; Taylor, G.; Thomas, D. A.

2016-11-01

The Synthetic Aperture Microwave Imaging (SAMI) system is a novel diagnostic consisting of an array of 8 independently phased antennas. At any one time, SAMI operates at one of the 16 frequencies in the range 10-34.5 GHz. The imaging beam is steered in software post-shot to create a picture of the entire emission surface. In SAMI's active probing mode of operation, the plasma edge is illuminated with a monochromatic source and SAMI reconstructs an image of the Doppler back-scattered (DBS) signal. By assuming that density fluctuations are extended along magnetic field lines, and knowing that the strongest back-scattered signals are directed perpendicular to the density fluctuations, SAMI's 2-D DBS imaging capability can be used to measure the pitch of the edge magnetic field. In this paper, we present preliminary pitch angle measurements obtained by SAMI on the Mega Amp Spherical Tokamak (MAST) at Culham Centre for Fusion Energy and on the National Spherical Torus Experiment Upgrade at Princeton Plasma Physics Laboratory. The results demonstrate encouraging agreement between SAMI and other independent measurements.

Preliminary measurements of the edge magnetic field pitch from 2-D Doppler backscattering in MAST and NSTX-U (invited).

PubMed

Vann, R G L; Brunner, K J; Ellis, R; Taylor, G; Thomas, D A

2016-11-01

The Synthetic Aperture Microwave Imaging (SAMI) system is a novel diagnostic consisting of an array of 8 independently phased antennas. At any one time, SAMI operates at one of the 16 frequencies in the range 10-34.5 GHz. The imaging beam is steered in software post-shot to create a picture of the entire emission surface. In SAMI's active probing mode of operation, the plasma edge is illuminated with a monochromatic source and SAMI reconstructs an image of the Doppler back-scattered (DBS) signal. By assuming that density fluctuations are extended along magnetic field lines, and knowing that the strongest back-scattered signals are directed perpendicular to the density fluctuations, SAMI's 2-D DBS imaging capability can be used to measure the pitch of the edge magnetic field. In this paper, we present preliminary pitch angle measurements obtained by SAMI on the Mega Amp Spherical Tokamak (MAST) at Culham Centre for Fusion Energy and on the National Spherical Torus Experiment Upgrade at Princeton Plasma Physics Laboratory. The results demonstrate encouraging agreement between SAMI and other independent measurements.

Preliminary Statistics from the NASA Alphasat Beacon Receiver in Milan, Italy

NASA Technical Reports Server (NTRS)

Zemba, Michael J.; Nessel, James A.; Morse, Jacquelynne R.

2015-01-01

NASA Glenn Research Center (GRC) and the Politecnico di Milano (POLIMI) have initiated a joint propagation campaign within the framework of the Alphasat propagation experiment to characterize rain attenuation, scintillation, and gaseous absorption effects of the atmosphere in the 40 GHz band. NASA GRC has developed and installed a KQ-band (20-40 GHz) beacon receiver at the POLIMI campus in Milan, Italy, which receives the 20-40 GHz signals broadcast from the Alphasat Aldo Paraboni TDP5 beacon payload. The primary goal of these measurements is to develop a physical model to improve predictions of communications systems performance within the Q-band. Herein, we provide an overview of the design and data calibration procedure, and present 6 months of preliminary statistics of the NASA propagation terminal, which has been installed and operating in Milan since May 2014. The Q-band receiver has demonstrated a dynamic range of 40 dB at an 8-Hz sampling rate. A weather station with an optical disdrometer is also installed to characterize rain drop size distribution for correlation with physical based models

Preliminary Statistics from the NASA Alphasat Beacon Receiver in Milan, Italy

NASA Technical Reports Server (NTRS)

Nessel, James; Zemba, Michael; Morse, Jacquelynne; Luini, Lorenzo; Riva, Carlo

2015-01-01

NASA Glenn Research Center (GRC) and the Politecnico di Milano (POLIMI) have initiated a joint propagation campaign within the framework of the Alphasat propagation experiment to characterize rain attenuation, scintillation, and gaseous absorption effects of the atmosphere in the 40 gigahertz band. NASA GRC has developed and installed a K/Q-band (20/40 gigahertz) beacon receiver at the POLIMI campus in Milan, Italy, which receives the 20/40 gigahertz signals broadcast from the Alphasat Aldo Paraboni TDP no. 5 beacon payload. The primary goal of these measurements is to develop a physical model to improve predictions of communications systems performance within the Q-band. Herein, we provide an overview of the design and data calibration procedure, and present 6 months of preliminary statistics of the NASA propagation terminal, which has been installed and operating in Milan since May 2014. The Q-band receiver has demonstrated a dynamic range of 40 decibels at an 8-hertz sampling rate. A weather station with an optical disdrometer is also installed to characterize rain drop size distribution for correlation with physical based models.

LDEF Experiment P0006 Linear Energy Transfer Spectrum Measurement (LETSME) quick look report

NASA Technical Reports Server (NTRS)

1990-01-01

A preliminary analysis of the various passive radiation detector materials included in the P0006 LETSME experiment flown on LDEF (Long Duration Exposure Facility) is presented. It consists of four tasks: (1) readout and analysis of thermoluminescent detectors (TLD); (2) readout and analysis of fission foil/mica detectors; (3) readout and analysis of (6)LiF/CR-39 detectors; and (4) preliminary processing and readout of CR-39 and polycarbonate plastic nuclear track detectors (PNTD).

Microwave remote sensing of snow experiment description and preliminary results

NASA Technical Reports Server (NTRS)

Ulaby, F. T. (Principal Investigator); Stiles, W. H.; Hanson, B. C.

1977-01-01

The active and passive microwave responses to snow were investigated at a site near Steamboat Springs, Colorado during the February and March winter months. The microwave equipment was mounted atop truck-mounted booms. Data were acquired at numerous frequencies, polarizations, and angles of incidence for a variety of snow conditions. The experiment description, the characteristics of the microwave and ground truth instruments, and the results of a preliminary analysis of a small portion of the total data volume acquired in Colorado are documented.

Built-in active sensing diagnostic system for civil infrastructure systems

NASA Astrophysics Data System (ADS)

Wu, Fan; Chang, Fu-Kuo

2001-07-01

A reliable, robust monitoring system can improve the maintenance of and provide safety protection for civil structures and therefore prolong their service lives. A built-in, active sensing diagnostic technique for civil structures has been under investigation. In this technique, piezoelectric materials are used as sensors/actuators to receive and generate signals. The transducers are embedded in reinforced concrete (RC) beams and are designed to detect damage, particularly debonding damage between the reinforcing bars and concrete. This paper presents preliminary results from a feasibility study of the technology. Laboratory experiments performed on RC beams, with piezo-electric sensors and actuators mounted on reinforced steel bars, have clearly demonstrated that the proposed technique could detect debonding damage. Analytical work, using a special purpose finite-element software, PZFlex, was also conducted to interpret the relationship between the measured data and actual debonding damage. Effectiveness of the proposed technique for detecting debonding damage in civil structures has been demonstrated.

Noncontact evaluation for interface states by photocarrier counting

NASA Astrophysics Data System (ADS)

Furuta, Masaaki; Shimizu, Kojiro; Maeta, Takahiro; Miyashita, Moriya; Izunome, Koji; Kubota, Hiroshi

2018-03-01

We have developed a noncontact measurement method that enables in-line measurement and does not have any test element group (TEG) formation. In this method, the number of photocarriers excited from the interface states are counted which is called “photocarrier counting”, and then the energy distribution of the interface states density (D it) is evaluated by spectral light excitation. In our previous experiment, the method used was a preliminary contact measurement method at the oxide on top of the Si wafer. We developed, at this time, a D it measurement method as a noncontact measurement with a gap between the probes and the wafer. The shallow trench isolation (STI) sidewall has more localized interface states than the region under the gate electrode. We demonstrate the noncontact measurement of trapped carriers from interface states using wafers of three different crystal plane orientations. The demonstration will pave the way for evaluating STI sidewall interface states in future studies.

Local effect of compression stockings on skin microcirculatory activity through the measurement of skin effective thermal conductivity.

PubMed

Grenier, Etienne; Gehin, Claudine; Lun, Bertrand; McAdams, Eric

2013-01-01

This paper presents a preliminary study to demonstrate the instantaneous local effect of compression stocking (Class 2) on skin microcirculatory activity. The measurement needs to be carefully performed as the sensor is placed under the garment. To assess the local effect of compression stockings, we use the ambulatory device Hematron located on the calf under the garment. Skin microcirculatory activity is assessed through the skin's effective thermal conductivity measurement. A specific housing for the sensor has been designed to avoid excessive pressure induced by the sensor when squeezed by stockings. The experiment, conducted on ten healthy subjects, comprised two stages: without and with compression stockings. Skin effective thermal conductivity was recorded at three successive positions (supine, sitting and standing). Significant improvement in skin microcirculatory activity was recorded by the Hematron device for the three positions. We have also demonstrated that Hematron sensor can be used under compression stockings.

Dirty liberals! Reminders of physical cleanliness influence moral and political attitudes.

PubMed

Helzer, Erik G; Pizarro, David A

2011-04-01

Many moral codes place a special emphasis on bodily purity, and manipulations that directly target bodily purity have been shown to influence a variety of moral judgments. Across two studies, we demonstrated that reminders of physical purity influence specific moral judgments regarding behaviors in the sexual domain as well as broad political attitudes. In Study 1, individuals in a public setting who were given a reminder of physical cleansing reported being more politically conservative than did individuals who were not given such a reminder. In Study 2, individuals reminded of physical cleansing in the laboratory demonstrated harsher moral judgments toward violations of sexual purity and were more likely to report being politically conservative than control participants. Together, these experiments provide further evidence of a deep link between physical purity and moral judgment, and they offer preliminary evidence that manipulations of physical purity can influence general (and putatively stable) political attitudes.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lincoln, D.E.

Preliminary analysis of two populations of Artemisia tridentata compared leaf chemical and physiological characteristics which influence herbivores. The proportion of sixteen of the volatile compounds differed significantly between the two populations; however, total yield of volatiles did not. This initial survey established the reliability of the procedure to quantitatively monitor plant responses to CO/sub 2/ enrichment and suggests that test samples be restricted to a single population. Four sesquiterpene lactones have been selected for the experimental quantitative HPLC analysis; all peaks have been assigned identities and have demonstrated high degree of reproducibility. Growth of Artemisia under high and low lightmore » at three CO/sub 2/ levels demonstrated that this species also undergoes a ''dilution'' of the leaf carbon content and is useful as test species for herbivory response to CO/sub 2/ induced effects. The initial experiment also showed that high irradiance is a necessary growth condition. 10 refs.« less

Student design projects in applied acoustics.

PubMed

Bös, Joachim; Moritz, Karsten; Skowronek, Adam; Thyes, Christian; Tschesche, Johannes; Hanselka, Holger

2012-03-01

This paper describes a series of student projects which are intended to complement theoretical education in acoustics and engineering noise control with practical experience. The projects are also intended to enhance the students' ability to work in a team, to manage a project, and to present their results. The projects are carried out in close cooperation with industrial partners so that the students can get a taste of the professional life of noise control engineers. The organization of such a project, its execution, and some of the results from the most recent student project are presented as a demonstrative example. This latest project involved the creation of noise maps of a production hall, the acoustic analysis of a packaging machine, and the acoustic analysis of a spiral vibratory conveyor. Upon completion of the analysis, students then designed, applied, and verified some simple preliminary noise reduction measures to demonstrate the potential of these techniques. © 2012 Acoustical Society of America

Pinosylvin-Based Polymers: Biodegradable Poly(Anhydride-Esters) for Extended Release of Antibacterial Pinosylvin.

PubMed

Bien-Aime, Stephan; Yu, Weiling; Uhrich, Kathryn E

2016-07-01

Pinosylvin is a natural stilbenoid known to exhibit antibacterial bioactivity against foodborne bacteria. In this work, pinosylvin is chemically incorporated into a poly(anhydride-ester) (PAE) backbone via melt-condensation polymerization, and characterized with respect to its physicochemical and thermal properties. In vitro release studies demonstrate that pinosylvin-based PAEs hydrolytically degrade over 40 d to release pinosylvin. Pseudo-first order kinetic experiments on model compounds, butyric anhydride and 3-butylstilbene ester, indicate that the anhydride linkages hydrolyze first, followed by the ester bonds to ultimately release pinosylvin. An antibacterial assay shows that the released pinosylvin exhibit bioactivity, while in vitro cytocompatibility studies demonstrate that the polymer is noncytotoxic toward fibroblasts. These preliminary findings suggest that the pinosylvin-based PAEs can serve as food preservatives in food packaging materials by safely providing antibacterial bioactivity over extended time periods. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

DNA Profiles of MTG (Moderat Tahan Gano) Oil Palm Variety Based on SSR Marker

NASA Astrophysics Data System (ADS)

Putri, L. A. P.; Setiado, H.; Hardianti, R.

2017-03-01

The oil palm, an economically important tree in Indonesia, has been one of the world’s major sources of edible oil and a significant precursor of biodiesel fuel. The objectives of this study were to know DNA profile of commercial MTG (Moderat Tahan Gano) oil palm variety collections. A total of 10 trees MTG oil palm variety were used for analysis. In this experiment, the DNA profile diversity was assessed using mEgCIR0174 and SSR-1 loci of oil palm’s specific SSR markers. The results of the experiment indicated out of 3 alleles of pcr product of mEgCIR0174 (198, 203 and 208 bp) and SSR-1 (201, 217 and 232 bp). These preliminary results demonstrated SSR marker can be used to evaluate genetic relatedness among trees of MTG (Moderat Tahan Gano) oil palm variety derived from different crossing or difference to desease resistance trait or misslabeled.

Serial and parallel power equipment with high-temperature superconducting elements

NASA Technical Reports Server (NTRS)

Bencze, Laszlo; Goebl, Nandor; Palotas, Bela; Vajda, Istvan

1995-01-01

One of the prospective, practical applications of high-temperature superconductors is the fault-current limitation in electrical energy networks. The development and testing of experimental HTSC serial current limiters have been reported in the literature. A Hungarian electric power company has proposed the development of a parallel equipment for arc suppressing both in the industrial and customers' networks. On the basis of the company's proposal the authors have outlined the scheme of a compound circuit that can be applied both for current limitation and arc suppressing. In this paper the design principles and methods of the shunt equipment are presented. These principles involve the electrical, mechanical and cryogenic aspects with the special view on the electrical and mechanical connection between the HTSC material and the current lead. Preliminary experiments and tests have been carried out to demonstrate the validity of the design principles developed. The results of the experiments and of the technological investigations are presented.

3D Cosmic Ray Muon Tomography from an Underground Tunnel

DOE PAGES

Guardincerri, Elena; Rowe, Charlotte Anne; Schultz-Fellenz, Emily S.; ...

2017-03-31

Here, we present an underground cosmic ray muon tomographic experiment imaging 3D density of overburden, part of a joint study with differential gravity. Muon data were acquired at four locations within a tunnel beneath Los Alamos, New Mexico, and used in a 3D tomographic inversion to recover the spatial variation in the overlying rock–air interface, and compared with a priori knowledge of the topography. Densities obtained exhibit good agreement with preliminary results of the gravity modeling, which will be presented elsewhere, and are compatible with values reported in the literature. The modeled rock–air interface matches that obtained from LIDAR withinmore » 4 m, our resolution, over much of the model volume. This experiment demonstrates the power of cosmic ray muons to image shallow geological targets using underground detectors, whose development as borehole devices will be an important new direction of passive geophysical imaging.« less

3D Cosmic Ray Muon Tomography from an Underground Tunnel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guardincerri, Elena; Rowe, Charlotte Anne; Schultz-Fellenz, Emily S.

Here, we present an underground cosmic ray muon tomographic experiment imaging 3D density of overburden, part of a joint study with differential gravity. Muon data were acquired at four locations within a tunnel beneath Los Alamos, New Mexico, and used in a 3D tomographic inversion to recover the spatial variation in the overlying rock–air interface, and compared with a priori knowledge of the topography. Densities obtained exhibit good agreement with preliminary results of the gravity modeling, which will be presented elsewhere, and are compatible with values reported in the literature. The modeled rock–air interface matches that obtained from LIDAR withinmore » 4 m, our resolution, over much of the model volume. This experiment demonstrates the power of cosmic ray muons to image shallow geological targets using underground detectors, whose development as borehole devices will be an important new direction of passive geophysical imaging.« less

Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil

PubMed Central

Brandl, Ferdinand; Bertrand, Nicolas; Lima, Eliana Martins; Langer, Robert

2015-01-01

Nanotechnology may offer fast and effective solutions for environmental clean-up. Herein, amphiphilic diblock copolymers are used to develop a platform of photosensitive core-shell nanoparticles. Irradiation with ultraviolet light removes the protective layer responsible for colloidal stability; as a result, the nanoparticles are rapidly and irreversibly converted to macroscopic aggregates. The associated phase separation allows measuring the partitioning of small molecules between the aqueous phase and nanoparticles; data suggests that interactions are enhanced by decreasing the particle size. Adsorption onto nanoparticles can be exploited to efficiently remove hydrophobic pollutants from water and contaminated soil. Preliminary in vivo experiments suggest that treatment with photocleavable nanoparticles can significantly reduce the teratogenicity of bisphenol A, triclosan and 17α-ethinyl estradiol without generating obviously toxic byproducts. Small-scale pilot experiments on wastewater, thermal printing paper and contaminated soil demonstrate the applicability of the approach. PMID:26196119

[Initial clinical experience of proton therapy at Shizuoka Cancer Center].

PubMed

Murayama, Shigeyuki; Fuji, Hiroshi; Yamashita, Haruo; Futami, Yasuyuki; Numano, Masumi; Harada, Hideyuki; Kamata, Minoru; Nishimura, Tetsuo

2005-10-01

To present the initial experience and preliminary clinical results of patients treated mainly with proton irradiation at the newly developed proton therapy facility at Shizuoka Cancer Center. We reviewed 125 patients who underwent proton therapy between July 2003 and December 2004. Of these 125 patients, 11 had head and neck malignancies, 15 non-small cell lung cancers, 22 hepatocellular carcinomas, 62 prostate cancers, and 15 other malignant tumors. Most patients experienced Grade 0-1 acute morbidities (NCI-CTC) in skin or mucosa, while a temporary Grade 2-3 reaction was observed in a high dose area. Response rates were 73% for H & N malignancies, 100% for NSCLC, and 77% for HCC. PSA evaluation for patients with prostate cancer revealed a high rate of complete response. The efficacy and safety of proton therapy at Shizuoka Cancer Center was demonstrated for patients with early-stage cancer or locally advanced disease.

3D Cosmic Ray Muon Tomography from an Underground Tunnel

NASA Astrophysics Data System (ADS)

Guardincerri, Elena; Rowe, Charlotte; Schultz-Fellenz, Emily; Roy, Mousumi; George, Nicolas; Morris, Christopher; Bacon, Jeffrey; Durham, Matthew; Morley, Deborah; Plaud-Ramos, Kenie; Poulson, Daniel; Baker, Diane; Bonneville, Alain; Kouzes, Richard

2017-05-01

We present an underground cosmic ray muon tomographic experiment imaging 3D density of overburden, part of a joint study with differential gravity. Muon data were acquired at four locations within a tunnel beneath Los Alamos, New Mexico, and used in a 3D tomographic inversion to recover the spatial variation in the overlying rock-air interface, and compared with a priori knowledge of the topography. Densities obtained exhibit good agreement with preliminary results of the gravity modeling, which will be presented elsewhere, and are compatible with values reported in the literature. The modeled rock-air interface matches that obtained from LIDAR within 4 m, our resolution, over much of the model volume. This experiment demonstrates the power of cosmic ray muons to image shallow geological targets using underground detectors, whose development as borehole devices will be an important new direction of passive geophysical imaging.

Nanoparticles with photoinduced precipitation for the extraction of pollutants from water and soil

NASA Astrophysics Data System (ADS)

Brandl, Ferdinand; Bertrand, Nicolas; Lima, Eliana Martins; Langer, Robert

2015-07-01

Nanotechnology may offer fast and effective solutions for environmental clean-up. Herein, amphiphilic diblock copolymers are used to develop a platform of photosensitive core-shell nanoparticles. Irradiation with ultraviolet light removes the protective layer responsible for colloidal stability; as a result, the nanoparticles are rapidly and irreversibly converted to macroscopic aggregates. The associated phase separation allows measuring the partitioning of small molecules between the aqueous phase and nanoparticles; data suggests that interactions are enhanced by decreasing the particle size. Adsorption onto nanoparticles can be exploited to efficiently remove hydrophobic pollutants from water and contaminated soil. Preliminary in vivo experiments suggest that treatment with photocleavable nanoparticles can significantly reduce the teratogenicity of bisphenol A, triclosan and 17α-ethinyl estradiol without generating obviously toxic byproducts. Small-scale pilot experiments on wastewater, thermal printing paper and contaminated soil demonstrate the applicability of the approach.

A preliminary experiment definition for video landmark acquisition and tracking

NASA Technical Reports Server (NTRS)

Schappell, R. T.; Tietz, J. C.; Hulstrom, R. L.; Cunningham, R. A.; Reel, G. M.

1976-01-01

Six scientific objectives/experiments were derived which consisted of agriculture/forestry/range resources, land use, geology/mineral resources, water resources, marine resources and environmental surveys. Computer calculations were then made of the spectral radiance signature of each of 25 candidate targets as seen by a satellite sensor system. An imaging system capable of recognizing, acquiring and tracking specific generic type surface features was defined. A preliminary experiment definition and design of a video Landmark Acquisition and Tracking system is given. This device will search a 10-mile swath while orbiting the earth, looking for land/water interfaces such as coastlines and rivers.

Bringing Science Public Outreach to Elementary Schools

NASA Astrophysics Data System (ADS)

Miller, Lucas; Speck, A.; Tinnin, A.

2012-01-01

Many science "museums” already offer fantastic programs for the general public, and even some aimed at elementary school kids. However, these venues are usually located in large cities and are only occasionally used as tools for enriching science education in public schools. Here we present preliminary work to establish exciting educational enrichment environments for public schools that do not easily have access to such facilities. This program is aimed at motivating children's interest in science beyond what they learn in the classroom setting. In this program, we use the experience and experiments/demonstrations developed at a large science museum (in this case, The St. Louis Science Center) and take them into a local elementary school. At the same time, students from the University of Missouri are getting trained on how to present these outreach materials and work with the local elementary schools. Our pilot study has started with implementation of presentations/demonstrations at Benton Elementary School within the Columbia Public School district, Missouri. The school has recently adopted a STEM (Science, Technology, Engineering, and Mathematics) centered learning system throughout all grade levels (K-5), and is therefore receptive to this effort. We have implemented a program in which we have given a series of scientific demonstrations at each grade level's lunch hour. Further enrichment ideas and plans include: addition demonstrations, hands-on experiments, and question and answer sessions. However, the application of these events would be to compliment the curriculum for the appropriate grade level at that time. The focus of this project is to develop public communications which links science museums, college students and local public schools with an emphasis on encouraging college science majors to share their knowledge and to strengthen their ability to work in a public environment.

Student perceptions of a community engagement experience: exploration of reflections on social responsibility and professional formation.

PubMed

Furze, Jennifer; Black, Lisa; Peck, Kirk; Jensen, Gail M

2011-08-01

Physical therapy educators are challenged to emphasize the importance of social responsibility as a vital curricular element of professional development. Through reflection, students are able to identify core values, beliefs, and attitudes as part of the professional development process. The purpose of this study was to explore student perceptions and values of a community engagement experience based upon frequency of participation. This qualitative research report investigated student perceptions of the community experience following participation. Data collection tools included an open-ended questionnaire and focus group interviews. Comparisons were made across data for participants who engaged in the activity one time versus multiple times. Data analysis revealed participation in the community engagement experience had a positive impact on most participants. One time only participants demonstrated increased self-awareness, contemplating change, and capacity to serve while more than one time participants described a deeper understanding of community, impact on others, and professional transformation. Student involvement in community engagement activities combined with structured reflection provided meaningful insight into participants' personal beliefs. The results suggest incorporation of community-based learning experiences into academic curriculum may be beneficial in the students' preliminary understanding of social responsibility.

Emotional experience with dyslexia and self-esteem: the protective role of perceived family support in late adulthood.

PubMed

Carawan, Lena W; Nalavany, Blace A; Jenkins, Carol

2016-01-01

Despite the growing body of evidence that suggests dyslexia persists through the life span, there is a dearth of research that explores the complicating factor of dyslexia in late adulthood. Based upon stress and coping theory, this study examined whether perceived family support protects the impact of negative emotional experience with dyslexia on self-esteem. Adults aged 21 years and older with diagnosed or self-reported dyslexia were participants in a web-based survey. A total of 224 individuals completed the survey. These findings are from the 50 participants who reported to be 60 years or older. Completed measures include their perception of family support, emotional experience with dyslexia, self-esteem, and demographic variables. Preliminary analysis revealed that negative emotional experience with dyslexia negatively impacts self-esteem. Hierarchical moderated regression analysis demonstrated that positive perceived family support significantly buffers, mitigates, and protects the effects of negative emotional experiences with dyslexia on self-esteem in individuals with dyslexia in late adulthood. In this study, family support promoted self-esteem because as a protective dynamic, it helped older adults cope with the emotional distress associated with dyslexia. Implications of these findings are discussed.

Fetoscopic single-layer repair of open spina bifida using a cellulose patch: preliminary clinical experience.

PubMed

Pedreira, Denise A L; Zanon, Nelci; de Sá, Renato A M; Acacio, Gregório L; Ogeda, Edilson; Belem, Teresa M L O U; Chmait, Ramen H; Kontopoulos, Eftichia; Quintero, Ruben A

2014-11-01

To report our preliminary clinical experience in the antenatal correction of open spina bifida (OSB) using a fetoscopic approach and a simplified closure technique. Four fetuses with lumbar-sacral defects were operated in utero from 25 to 27 weeks. Surgeries were performed percutaneously under general anesthesia using three trocars and partial carbon dioxide insufflation. After dissection of the neural placode, the surrounding skin was closed over a cellulose patch using a single continuous stitch. Surgical closure was successful in three of the four cases. All successful cases showed improvement of the hindbrain herniation and no neonatal neurosurgical repair was required in two cases. Delivery occurred between 31 and 33 weeks, and no fetal or neonatal deaths occurred. Ventriculoperitoneal shunting was not needed in two out of the 3 successful cases. Our preliminary experience suggests that definitive fetoscopic repair of OSB is feasible using our innovative surgical technique. A phase I trial for the fetoscopic correction of OSB with this technique is currently being conducted.

Evaluation and Preliminary Results of the New USNO PPS Timing Receiver

DTIC Science & Technology

2000-11-01

timing receiver, one may currently obtain raw pseudorange and carrier-phase data by periodically downloading such data from a flashcard . Several...preliminary experiments have been performed using data collected from the prototype TTR- 12 receivers’ flashcards and geodetic GPS carrier-phase techniques

The Clinical/Practicum Experience in Professional Preparation: Preliminary Findings

ERIC Educational Resources Information Center

Ralph, Edwin George; Walker, Keith; Wimmer, Randy

2008-01-01

The authors synthesize preliminary findings from an interdisciplinary study of the practicum/clinical phase of undergraduate pre-service education in the professions. Early data analysis identified similarities and differences across disciplines in terms of: (a) the terminology describing each practicum program, (b) the programs' key…

The NASA Juncture Flow Experiment: Goals, Progress, and Preliminary Testing (Invited)

NASA Technical Reports Server (NTRS)

Rumsey, Christopher L.; Neuhart, Danny H.; Kegerise, Michael A.

2016-01-01

NASA has been working toward designing and conducting a juncture flow experiment on a wing-body aircraft configuration. The experiment is planned to provide validation-quality data for CFD that focuses on the onset and progression of a separation bubble near the wing-body juncture trailing edge region. This paper describes the goals and purpose of the experiment. Although currently considered unreliable, preliminary CFD analyses of several different configurations are shown. These configurations have been subsequently tested in a series of "risk-reduction" wind tunnel tests, in order to help down-select to a final configuration that will attain the desired flow behavior. The risk-reduction testing at the higher Reynolds number has not yet been completed (at the time of this writing), but some results from one of the low-Reynolds-number experiments are shown.

Sound-Field Amplification: Preliminary Information Regarding Special Education Referrals

ERIC Educational Resources Information Center

Flexer, C.; Long, S.

2004-01-01

In this clinical exchange, the authors discuss acoustic accessibility and sound-field amplification in general education classrooms. They bridge theory to practice by presenting preliminary information from two different school systems demonstrating how an improved signal-to-noise ratio can have a positive impact on special education referrals.

Scanning Raman Lidar Measurements During the WVIOP2000 and AFWEX Field Experiments

NASA Technical Reports Server (NTRS)

Whiteman, David N.; Evans, K. D.; Berkoff, T. B.; Demoz, B. D.; DiGirolamo, P.; Smith, David E. (Technical Monitor)

2001-01-01

The NASA/Goddard Space Flight Center Scanning Raman Lidar (SRL) participated in the Water Vapor IOP 2000 (WVIOP2000) and ARM FIRE Water Vapor Experiment (AFWEX) at the DOE SGP CART site in northern Oklahoma. These experiments occurred during the period of September and December, 2000. The goals of both the WVIOP2000 and AFWEX were to better characterize the water vapor measurement capability of numerous sensors in the lower atmosphere and upper troposphere, respectively. The SRL received several hardware upgrades in anticipation of these experiments that permitted improved measurements of water vapor during the daytime and in the upper troposphere (UT). The daytime SRL water vapor error statistics were demonstrated a factor of 2-3 improvement compared to the permanently stationed CART Raman lidar (CARL). The performance of the SRL in the UT showed improvements as well. The technological upgrades that permitted these improved SRL measurements could also be implemented in the CARL system. Data examples demonstrating the new daytime and upper tropospheric measurement capability of the SRL will be shown at the meeting. In addition, preliminary analysis will be presented on several topics: 1) inter comparison of the water vapor measurements for several water vapor sensors including SRL, CARL, the NASA/Langley Lidar Atmospheric Sensing Experiment (LASE) flown onboard the NASA DC-8, in-situ sensors flown on the DC-8, and the Max Planck Institute Differential Absorption Lidar 2) comparison of cirrus cloud measurements using SRL and CARL and 3) case studies of meteorological events that occurred during the IOPs such as a cold frontal passage on the night of September 23.

Protective role of parnaparin in reducing systemic inflammation and atherosclerotic plaque formation in ApoE-/- mice.

PubMed

Artico, Marco; Riganò, Rachele; Buttari, Brigitta; Profumo, Elisabetta; Ionta, Brunella; Bosco, Sandro; Rasile, Manuela; Bianchi, Enrica; Bruno, Moira; Fumagalli, Lorenzo

2011-04-01

Atherosclerosis is a degenerative disease whose role in the onset and development of cardiovascular pathologies and complications is of importance. Due to its silent but progressive development, and considering the endothelial, immunological and inflammatory processes that are involved in its clinical course, this still relatively unknown pathological condition has been and continues to be a matter of investigation worldwide. Our experience with previous studies on atherosclerosis led us to investigate the possible influence of a low molecular weight heparin (LMWH) - Parnaparin® on the development and clinical course of atherosclerosis in double knock-out laboratory animals (ApoE-/- mice). Our experiments demonstrated a possible role of Parnaparin (PNP) in the control of atherogenic disease. In fact, in treated mice vs. untreated ones, PNP reduced the number and the size of atherosclerotic lesions in the aortic wall, as well as the development of liver steatosis, which was massive in untreated animals and moderate in treated ones. These preliminary observations require further clinical studies, but demonstrate a possible role of Parnaparin in the control of the development and clinical evolution of atherosclerosis and liver steatosis in laboratory animals.

Assessment of MARMOT Grain Growth Model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fromm, B.; Zhang, Y.; Schwen, D.

2015-12-01

This report assesses the MARMOT grain growth model by comparing modeling predictions with experimental results from thermal annealing. The purpose here is threefold: (1) to demonstrate the validation approach of using thermal annealing experiments with non-destructive characterization, (2) to test the reconstruction capability and computation efficiency in MOOSE, and (3) to validate the grain growth model and the associated parameters that are implemented in MARMOT for UO 2. To assure a rigorous comparison, the 2D and 3D initial experimental microstructures of UO 2 samples were characterized using non-destructive Synchrotron x-ray. The same samples were then annealed at 2273K for grainmore » growth, and their initial microstructures were used as initial conditions for simulated annealing at the same temperature using MARMOT. After annealing, the final experimental microstructures were characterized again to compare with the results from simulations. So far, comparison between modeling and experiments has been done for 2D microstructures, and 3D comparison is underway. The preliminary results demonstrated the usefulness of the non-destructive characterization method for MARMOT grain growth model validation. A detailed analysis of the 3D microstructures is in progress to fully validate the current model in MARMOT.« less

System Management in UK Libraries: Some Preliminary Findings of a Survey.

ERIC Educational Resources Information Center

Muirhead, Graeme A.

1992-01-01

A cross-section of libraries in the United Kingdom was surveyed to investigate the prevalence of systems librarians and their education, work experience, duties, and professional activities. Preliminary findings of one section of the questionnaire indicate that systems librarians are generally associated with larger institutions that have large…

Measurement data preprocessing in a radar-based system for monitoring of human movements

NASA Astrophysics Data System (ADS)

Morawski, Roman Z.; Miȩkina, Andrzej; Bajurko, Paweł R.

2015-02-01

The importance of research on new technologies that could be employed in care services for elderly people is highlighted. The need to examine the applicability of various sensor systems for non-invasive monitoring of the movements and vital bodily functions, such as heart beat or breathing rhythm, of elderly persons in their home environment is justified. An extensive overview of the literature concerning existing monitoring techniques is provided. A technological potential behind radar sensors is indicated. A new class of algorithms for preprocessing of measurement data from impulse radar sensors, when applied for elderly people monitoring, is proposed. Preliminary results of numerical experiments performed on those algorithms are demonstrated.

LISA Pathfinder: A Mission Status

NASA Astrophysics Data System (ADS)

Hewitson, Martin; LISA Pathfinder Team Team

2016-03-01

On December 3rd at 04:04 UTC, The European Space Agency launched the LISA Pathfinder satellite on board a VEGA rocket from Kourou in French Guiana. After a series of orbit raising manoeuvres and a 2 month long transfer orbit, LISA Pathfinder arrived at L1. Following a period of commissioning, the science operations commenced at the start of March, beginning the demonstration of technologies and methodologies which pave the way for a future large-scale gravitational wave observatory in space. This talk will present the scientific goals of the mission, discuss the technologies being tested, elucidate the link to a future space-based observatory, such as LISA, and present preliminary results from the in-orbit operations and experiments.

ECR plasma thruster research - Preliminary theory and experiments

NASA Technical Reports Server (NTRS)

Sercel, Joel C.; Fitzgerald, Dennis J.

1989-01-01

A preliminary theory of the operation of the electron-cyclotron-resonance (ECR) plasma thruster is described along with an outline of recent experiments. This work is presented to communicate the status of an ongoing research effort directed at developing a unified theory to quantitatively describe the operation of the ECR plasma thruster. The theory is presented as a set of nonlinear ordinary differential equations and boundary conditions which describe the plasma density, velocity, and electron temperature. Diagnostic tools developed to measure plasma conditions in the existing research device are described.

Sounding-Diagnosed Convective Environments and Preliminary Energy Budgets Diagnosed during the TRMM Field Campaigns

NASA Technical Reports Server (NTRS)

Halverson, Jeffrey B.; Roy, Biswadev; O'CStarr, David (Technical Monitor)

2002-01-01

An overview of mean convective thermodynamic and wind profiles for the Tropical Rainfall Measuring Mission (TRMM) Large Scale Biosphere-Atmosphere Experiment (LBA) and Kwajalein Experiment (KWAJEX) field campaigns will be presented, highlighting the diverse continental and marine tropical environments in which rain clouds and mesoscale convective systems evolved. An assessment of ongoing sounding quality control procedures will be shown. Additionally, we will present preliminary budgets of sensible heat source (Q1) and apparent moisture sink (Q2), which have been diagnosed from the various sounding networks.

New advances in the partial-reflection-drifts experiment using microprocessors

NASA Technical Reports Server (NTRS)

Ruggerio, R. L.; Bowhill, S. A.

1982-01-01

Improvements to the partial reflection drifts experiment are completed. The results of the improvements include real time processing and simultaneous measurements of the D region with coherent scatter. Preliminary results indicate a positive correlation between drift velocities calculated by both methods during a two day interval. The possibility now exists for extended observations between partial reflection and coherent scatter. In addition, preliminary measurements could be performed between partial reflection and meteor radar to complete a comparison of methods used to determine velocities in the D region.

Robotic Single-Site Surgery for Female-to-Male Transsexuals: Preliminary Experience

PubMed Central

Bogliolo, Stefano; Cassani, Chiara; Babilonti, Luciana; Gardella, Barbara; Zanellini, Francesca; Santamaria, Valentina; Nappi, Rossella Elena; Spinillo, Arsenio

2014-01-01

Hysterectomy with bilateral salpingo-oophorectomy is a part of gender reassignment surgery for the treatment of female-to-male transsexualism. Over the last years many efforts were made in order to reduce invasiveness of laparoscopic and robotic surgery such as the introduction of single-site approach. We report our preliminary experience on single-site robotic hysterectomy for cross-sex reassignment surgery. Our data suggest that single-site robotic hysterectomy is feasible and safe in female-to-male transsexualism with some benefits in terms of postoperative pain and aesthetic results. PMID:24982976

Development of a verification program for deployable truss advanced technology

NASA Technical Reports Server (NTRS)

Dyer, Jack E.

1988-01-01

Use of large deployable space structures to satisfy the growth demands of space systems is contingent upon reducing the associated risks that pervade many related technical disciplines. The overall objectives of this program was to develop a detailed plan to verify deployable truss advanced technology applicable to future large space structures and to develop a preliminary design of a deployable truss reflector/beam structure for use a a technology demonstration test article. The planning is based on a Shuttle flight experiment program using deployable 5 and 15 meter aperture tetrahedral truss reflections and a 20 m long deployable truss beam structure. The plan addresses validation of analytical methods, the degree to which ground testing adequately simulates flight and in-space testing requirements for large precision antenna designs. Based on an assessment of future NASA and DOD space system requirements, the program was developed to verify four critical technology areas: deployment, shape accuracy and control, pointing and alignment, and articulation and maneuvers. The flight experiment technology verification objectives can be met using two shuttle flights with the total experiment integrated on a single Shuttle Test Experiment Platform (STEP) and a Mission Peculiar Experiment Support Structure (MPESS). First flight of the experiment can be achieved 60 months after go-ahead with a total program duration of 90 months.

Accessing defect dynamics using intense, nanosecond pulsed ion beams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Persaud, A.; Barnard, J. J.; Guo, H.

2015-06-18

Gaining in-situ access to relaxation dynamics of radiation induced defects will lead to a better understanding of materials and is important for the verification of theoretical models and simulations. We show preliminary results from experiments at the new Neutralized Drift Compression Experiment (NDCX-II) at Lawrence Berkeley National Laboratory that will enable in-situ access to defect dynamics through pump-probe experiments. Here, the unique capabilities of the NDCX-II accelerator to generate intense, nanosecond pulsed ion beams are utilized. Preliminary data of channeling experiments using lithium and potassium ions and silicon membranes are shown. We compare these data to simulation results using Crystalmore » Trim. Furthermore, we discuss the improvements to the accelerator to higher performance levels and the new diagnostics tools that are being incorporated.« less

Spacelab payload accommodation handbook. Preliminary issue

NASA Technical Reports Server (NTRS)

1976-01-01

The main characteristics of the Spacelab system are described. Sufficient information on Spacelab capabilities is provided to enable individual experimenters or payload planning groups to determine how their payload equipment can be accomodated by Spacelab topics discussed include major spacelab/experiment interfaces; Spacelab payload support systems and requirements the experiments must comply with to allow experiment design; and development and integration up to a level where a group of individual experiments are integrated into a complete Spacelab payload using Spacelab racks/floors and pallet segments. Integration of a complete Spacelab payload with Spacelab subsystems, primary module structure etc., integration of Spacelab with the Orbiter and basic operational aspects are also covered in this preliminary edition of the handbook which reflects the current Spacelab baseline design and is for information only.

Exercise-Based Oncology Rehabilitation: Leveraging the Cardiac Rehabilitation Model

PubMed Central

Dittus, Kim L.; Lakoski, Susan G.; Savage, Patrick D.; Kokinda, Nathan; Toth, Michael; Stevens, Diane; Woods, Kimberly; O’Brien, Patricia; Ades, Philip A.

2014-01-01

PURPOSE The value of exercise and rehabilitative interventions for cancer survivors is increasingly clear and oncology rehabilitation programs could provide these important interventions. However, a pathway to create oncology rehabilitation has not been delineated. Community-based cardiac rehabilitation (CR) programs staffed by health care professionals with experience in providing rehabilitation and secondary prevention services to individuals with coronary heart disease are widely available and provide a potential model and location for oncology rehabilitation programs. Our purpose is to outline the rehabilitative needs of cancer survivors and demonstrate how oncology rehabilitation can be created using a cardiac rehabilitation model. METHODS We identify the impairments associated with cancer and its therapy that respond to rehabilitative interventions. Components of the CR model that would benefit cancer survivors are described. An example of an oncology rehabilitation program using a CR model is presented. RESULTS Cancer survivors have impairments associated with cancer and its therapy that improve with rehabilitation. Our experience demonstrates that effective rehabilitation services can be provided utilizing an existing CR infrastructure. Few adjustments to current cardiac rehabilitation models would be needed to provide oncology rehabilitation. Preliminary evidence suggests that cancer survivors participating in an oncology rehabilitation program experience improvements in psychological and physiologic parameters. CONCLUSIONS Utilizing the CR model of rehabilitative services and disease management provides a much needed mechanism to bring oncology rehabilitation to larger numbers of cancer survivors. PMID:25407596

Introduction of Cooperative Vehicle-to-Infrastructure Systems to Improve Speed Harmonization

DOT National Transportation Integrated Search

2016-03-01

This project executed a preliminary experiment of vehicle-to-infrastructure (V2I)-based speed harmonization in which speed guidance was communicated directly to vehicles. This experiment involved a set of micro-simulation experiments and a limited nu...

Laser Ablation Increases PEM/Catalyst Interfacial Area

NASA Technical Reports Server (NTRS)

Whitacre, Jay; Yalisove, Steve

2009-01-01

An investigational method of improving the performance of a fuel cell that contains a polymer-electrolyte membrane (PEM) is based on the concept of roughening the surface of the PEM, prior to deposition of a thin layer of catalyst, in order to increase the PEM/catalyst interfacial area and thereby increase the degree of utilization of the catalyst. The roughening is done by means of laser ablation under carefully controlled conditions. Next, the roughened membrane surface is coated with the thin layer of catalyst (which is typically platinum), then sandwiched between two electrode/catalyst structures to form a membrane/ele c t - rode assembly. The feasibility of the roughening technique was demonstrated in experiments in which proton-conducting membranes made of a perfluorosulfonic acid-based hydrophilic, protonconducting polymer were ablated by use of femtosecond laser pulses. It was found that when proper combinations of the pulse intensity, pulse-repetition rate, and number of repetitions was chosen, the initially flat, smooth membrane surfaces became roughened to such an extent as to be converted to networks of nodules interconnected by filaments (see Figure 1). In further experiments, electrochemical impedance spectroscopy (EIS) was performed on a pristine (smooth) membrane and on two laser-roughened membranes after the membranes were coated with platinum on both sides. Some preliminary EIS data were interpreted as showing that notwithstanding the potential for laser-induced damage, the bulk conductivities of the membranes were not diminished in the roughening process. Other preliminary EIS data (see Figure 2) were interpreted as signifying that the surface areas of the laser-roughened membranes were significantly greater than those of the smooth membrane. Moreover, elemental analyses showed that the sulfur-containing molecular groups necessary for proton conduction remained intact, even near the laser-roughened surfaces. These preliminary results can be taken as indications that laser-roughened PEMs should function well in fuel cells and, in particular, should exhibit current and power densities greater than those attainable by use of smooth membranes.

Parametric analyses of planned flowing uranium hexafluoride critical experiments

NASA Technical Reports Server (NTRS)

Rodgers, R. J.; Latham, T. S.

1976-01-01

Analytical investigations were conducted to determine preliminary design and operating characteristics of flowing uranium hexafluoride (UF6) gaseous nuclear reactor experiments in which a hybrid core configuration comprised of UF6 gas and a region of solid fuel will be employed. The investigations are part of a planned program to perform a series of experiments of increasing performance, culminating in an approximately 5 MW fissioning uranium plasma experiment. A preliminary design is described for an argon buffer gas confined, UF6 flow loop system for future use in flowing critical experiments. Initial calculations to estimate the operating characteristics of the gaseous fissioning UF6 in a confined flow test at a pressure of 4 atm, indicate temperature increases of approximately 100 and 1000 K in the UF6 may be obtained for total test power levels of 100 kW and 1 MW for test times of 320 and 32 sec, respectively.

A preliminary study of a cryogenic equivalence principle experiment on Shuttle

NASA Technical Reports Server (NTRS)

Everitt, C. W. F.; Worden, P. W., Jr.

1985-01-01

The Weak Equivalence Principle is the hypothesis that all test bodies fall with the same acceleration in the same gravitational field. The current limit on violations of the Weak Equivalence Principle, measured by the ratio of the difference in acceleration of two test masses to their average acceleration, is about 3 parts in one-hundred billion. It is anticipated that this can be improved in a shuttle experiment to a part in one quadrillion. Topics covered include: (1) studies of the shuttle environment, including interference with the experiment, interfacing to the experiment, and possible alternatives; (2) numerical simulations of the proposed experiment, including analytic solutions for special cases of the mass motion and preliminary estimates of sensitivity and time required; (3) error analysis of several noise sources such as thermal distortion, gas and radiation pressure effects, and mechanical distortion; and (4) development and performance tests of a laboratory version of the instrument.

Possession experiences in dissociative identity disorder: a preliminary study.

PubMed

Ross, Colin A

2011-01-01

Dissociative trance disorder, which includes possession experiences, was introduced as a provisional diagnosis requiring further study in the Diagnostic and Statistical Manual of Mental Disorders (4th ed.). Consideration is now being given to including possession experiences within dissociative identity disorder (DID) in the Diagnostic and Statistical Manual of Mental Disorders (5th ed.), which is due to be published in 2013. In order to provide empirical data relevant to the relationship between DID and possession states, I analyzed data on the prevalence of trance, possession states, sleepwalking, and paranormal experiences in 3 large samples: patients with DID from North America; psychiatric outpatients from Shanghai, China; and a general population sample from Winnipeg, Canada. Trance, sleepwalking, paranormal, and possession experiences were much more common in the DID patients than in the 2 comparison samples. The study is preliminary and exploratory in nature because the samples were not matched in any way.

The March 1985 demonstration of the fiducial network concept for GPS geodesy: A preliminary report

NASA Technical Reports Server (NTRS)

Davidson, J. M.; Thornton, C. L.; Dixon, T. H.; Vegos, C. J.; Young, L. E.; Yunck, T. P.

1986-01-01

The first field tests in preparation for the NASA Global Positioning System (GPS) Caribbean Initiative were conducted in late March and Early April of 1985. The GPS receivers were located at the POLARIS Very Long Base Interferometry (VLBI) stations at Westford, Massachusetts; Richmond, Florida; and Ft. Davis, Texas; and at the Mojave, Owens Valley, and Hat Creek VLBI stations in California. Other mobile receivers were placed near Mammoth Lakes, California; Pt. Mugu, California; Austin, Texas; and Dahlgren, Virginia. These sites were equipped with a combination of GPS receiver types, including SERIES-X, TI-4100 and AFGL dual frequency receivers. The principal objectives of these tests were the demonstration of the fiducial network concept for precise GPS geodesy, the performance assessment of the participating GPS receiver types, and to conduct the first in a series of experiments to monitor ground deformation in the Mammoth Lakes-Long Valley caldera region in California. Other objectives included the testing of the water vapor radiometers for the calibration of GPS data, the development of efficient procedures for planning and coordinating GPS field exercise, the establishment of institutional interfaces for future cooperating ventures, the testing of the GPS Data Analysis Software (GIPSY, for GPS Inferred Positioning SYstem), and the establishment of a set of calibration baselines in California. Preliminary reports of the success of the field tests, including receiver performance and data quality, and on the status of the data analysis software are given.

A Preliminary Investigation of a Fluid-Filled ECG-Triggered Anti-G Suit.

DTIC Science & Technology

1994-02-01

the abdomen, anterior thighs, and calves. In Australia, Dr. F.S. Cotton of Sydney developed a pneumatic anti-G suit using the Royal Australian Air...Acceleration Stress: Model Studies and Preliminary Experiments. IEEE Transactions on Biomedical Engineering, Feb 1985, Vol BME -32(2):158-165. 10 13. Lambert

A Preliminary Assessment of Phase Separator Ground-Based and Reduced-Gravity Testing for ALS Systems

NASA Technical Reports Server (NTRS)

Hall, Nancy Rabel

2006-01-01

A viewgraph presentation of phase separator ground-based and reduced-gravity testing for Advanced Life Support (ALS) systems is shown. The topics include: 1) Multiphase Flow Technology Program; 2) Types of Separators; 3) MOBI Phase Separators; 4) Experiment set-up; and 5) Preliminary comparison/results.

ICT and UD: Preliminary Study for Recommendations to Design Accessible University Courses.

PubMed

Pagliara, Silvio Marcello; Sánchez Utgé, Marta; De Anna, Lucia

2017-01-01

Starting from the Universal Design in the educational context principles, the experiences gained during the FIRB project "Net@ccessibility" and the high-education courses for teachers' specialization on special education, this research will focus on preliminary studies in order to define the recommendations for designing accessible university courses.

Factors affecting weight gain and dietary intake in Latino males residing in Mississippi: A preliminary study

USDA-ARS?s Scientific Manuscript database

Research indicates that as Latinos become more acculturated to the United States, their diet changes and they experience weight gain. There is also a high incidence of depression in this population. The purpose of this preliminary study was to examine the correlations between sociodemographic factor...

Virtual Reality in Neurointervention.

PubMed

Ong, Chin Siang; Deib, Gerard; Yesantharao, Pooja; Qiao, Ye; Pakpoor, Jina; Hibino, Narutoshi; Hui, Ferdinand; Garcia, Juan R

2018-06-01

Virtual reality (VR) allows users to experience realistic, immersive 3D virtual environments with the depth perception and binocular field of view of real 3D settings. Newer VR technology has now allowed for interaction with 3D objects within these virtual environments through the use of VR controllers. This technical note describes our preliminary experience with VR as an adjunct tool to traditional angiographic imaging in the preprocedural workup of a patient with a complex pseudoaneurysm. Angiographic MRI data was imported and segmented to create 3D meshes of bilateral carotid vasculature. The 3D meshes were then projected into VR space, allowing the operator to inspect the carotid vasculature using a 3D VR headset as well as interact with the pseudoaneurysm (handling, rotation, magnification, and sectioning) using two VR controllers. 3D segmentation of a complex pseudoaneurysm in the distal cervical segment of the right internal carotid artery was successfully performed and projected into VR. Conventional and VR visualization modes were equally effective in identifying and classifying the pathology. VR visualization allowed the operators to manipulate the dataset to achieve a greater understanding of the anatomy of the parent vessel, the angioarchitecture of the pseudoaneurysm, and the surface contours of all visualized structures. This preliminary study demonstrates the feasibility of utilizing VR for preprocedural evaluation in patients with anatomically complex neurovascular disorders. This novel visualization approach may serve as a valuable adjunct tool in deciding patient-specific treatment plans and selection of devices prior to intervention.

Comparison-Bot: an Automated Preliminary-Final Report Comparison System.

PubMed

Kalaria, Amit D; Filice, Ross W

2016-06-01

Regular comparison of preliminary to final reports is a critical part of radiology resident and fellow education as prior research has documented substantial preliminary to final discrepancies. Unfortunately, there are many barriers to this comparison: high study volume; overnight rotations without an attending; the ability to finalize reports remotely; the subtle nature of many changes; and lack of easy access to the preliminary report after finalization. We developed a system that automatically compiles and emails a weekly summary of report differences for all residents and fellows. Trainees can also create a custom report using a date range of their choice and can view this data on a resident dashboard. Differences between preliminary and final reports are clearly highlighted with links to the associated study in Picture Archiving and Communication Systems (PACS) for efficient review and learning. Reports with more changes, particularly changes made in the impression, are highlighted to focus attention on those exams with substantive edits. Our system provides an easy way for trainees to review changes to preliminary reports with immediate access to the associated images, thereby improving their educational experience. Departmental surveys showed that our report difference summary is easy to understand and improves the educational experience of our trainees. Additionally, interesting descriptive statistics help us understand how reports are changed by trainee level, by attending, and by exam type. Finally, this system can be easily ported to other departments who have access to their Health Level 7 (HL7) data.

Development of an YBCO coil with SSTC conductors for high field application

NASA Astrophysics Data System (ADS)

Shi, Y.; Liu, H. J.; Liu, F.; Tan, Y. F.; Jin, H.; Yu, M.; Lei, L.; Guo, L.; Hong, Z. Y.

2018-07-01

With the continuous reduction of the production costs and improvement of the transport performance, YBCO coated conductor is the most promising candidate for the high field magnet application due to its high irreversibility field and strong mechanical properties. Presently a stable production capacity of the YBCO conductors has been achieved by Shanghai Superconducting Technology Co., Ltd (SSTC) in China. Therefore, the demand in high field application with YBCO conductors is growing in China. This paper describes the design, fabrication and preliminary experiment of a solenoid coil with YBCO conductors supplied by SSTC to validate the possibility of high field application. Four same double pancakes were manufactured and assembled for the YBCO coil where the outer diameter and height was 54.3 and 48 mm respectively to match the dimensional limitation of the 14 T background magnets. The critical current (Ic) of YBCO conductors was obtained by measuring as a function of the applied field perpendicular to the YBCO conductor surface which provides the necessary input parameters for preliminary performance evaluation of the coil. Finally the preliminary test and discussion at 77 and 4.2 K were carried out. The consistency of four double pancakes Ic was achieved. The measured results indicate that the fabrication technology of HTS coil is reliable which gives the conference for the in-field test in high field application. This YBCO coil is the first demonstration of the SSTC YBCO coated conductors.

Anaesthesiologists' views on the need for point-of-care information system in the operating room: a survey of the European Society of Anaesthesiologists.

PubMed

Perel, A; Berkenstadt, H; Ziv, A; Katzenelson, R; Aitkenhead, A

2004-11-01

In this preliminary study we wanted to explore the attitudes of anaesthesiologists to a point-of-care information system in the operating room. The study was conducted as a preliminary step in the process of developing such a system by the European Society of Anaesthesiologists (ESA). A questionnaire was distributed to all 2240 attendees of the ESA's annual meeting in Gothenburg, Sweden, which took place in April 2001. Of the 329 responders (response rate of 14.6%), 79% were qualified specialists with more than 10 yr of experience (68%), mostly from Western Europe. Most responders admitted to regularly experiencing lack of medical knowledge relating to real-time patient care at least once a month (74%) or at least once a week (46%), and 39% admitted to having made errors during anaesthesia due to lack of medical information that can be otherwise found in a handbook. The choice ofa less optimal but more familiar approach to patient management due to lack of knowledge was reported by 37%. Eighty-eight percent of responders believe that having a point-of-care information system for the anaesthesiologists in the operating room is either important or very important. This preliminary survey demonstrates that lack of knowledge of anaesthesiologists may be a significant source of medical errors in the operating room, and suggests that a point-of-care information system for the anaesthesiologist may be of value.

Modular space station phase B extension preliminary system design. Volume 3: Experiment analyses

NASA Technical Reports Server (NTRS)

Wengrow, G. L.; Lillenas, A. N.

1972-01-01

Experiment analysis tasks performed during program definition study are described. Experiment accommodation and scheduling, and defining and implementing the laboratory evolution are discussed. The general purpose laboratory requirements and concepts are defined, and supplemental studies are reported.

Characterization of Bond Strength of U-Mo Fuel Plates Using the Laser Shockwave Technique: Capabilities and Preliminary Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

J. A. Smith; D. L. Cottle; B. H. Rabin

2013-09-01

This report summarizes work conducted to-date on the implementation of new laser-based capabilities for characterization of bond strength in nuclear fuel plates, and presents preliminary results obtained from fresh fuel studies on as-fabricated monolithic fuel consisting of uranium-10 wt.% molybdenum alloys clad in 6061 aluminum by hot isostatic pressing. Characterization involves application of two complementary experimental methods, laser-shock testing and laser-ultrasonic imaging, collectively referred to as the Laser Shockwave Technique (LST), that allows the integrity, physical properties and interfacial bond strength in fuel plates to be evaluated. Example characterization results are provided, including measurement of layer thicknesses, elastic properties ofmore » the constituents, and the location and nature of generated debonds (including kissing bonds). LST provides spatially localized, non-contacting measurements with minimum specimen preparation, and is ideally suited for applications involving radioactive materials, including irradiated materials. The theoretical principles and experimental approaches employed in characterizing nuclear fuel plates are described, and preliminary bond strength measurement results are discussed, with emphasis on demonstrating the capabilities and limitations of these methods. These preliminary results demonstrate the ability to distinguish bond strength variations between different fuel plates. Although additional development work is necessary to validate and qualify the test methods, these results suggest LST is viable as a method to meet fuel qualification requirements to demonstrate acceptable bonding integrity.« less

Fiber optical parametric amplifiers in optical communication systems

PubMed Central

Marhic (†), Michel E; Andrekson, Peter A; Petropoulos, Periklis; Radic, Stojan; Peucheret, Christophe; Jazayerifar, Mahmoud

2015-01-01

The prospects for using fiber optical parametric amplifiers (OPAs) in optical communication systems are reviewed. Phase-insensitive amplifiers (PIAs) and phase-sensitive amplifiers (PSAs) are considered. Low-penalty amplification at/or near 1 Tb/s has been achieved, for both wavelength- and time-division multiplexed formats. High-quality mid-span spectral inversion has been demonstrated at 0.64 Tb/s, avoiding electronic dispersion compensation. All-optical amplitude regeneration of amplitude-modulated signals has been performed, while PSAs have been used to demonstrate phase regeneration of phase-modulated signals. A PSA with 1.1-dB noise figure has been demonstrated, and preliminary wavelength-division multiplexing experiments have been performed with PSAs. 512 Gb/s have been transmitted over 6,000 km by periodic phase conjugation. Simulations indicate that PIAs could reach data rate x reach products in excess of 14,000 Tb/s × km in realistic wavelength-division multiplexed long-haul networks. Technical challenges remaining to be addressed in order for fiber OPAs to become useful for long-haul communication networks are discussed. PMID:25866588

Synthesis and in vivo magnetic resonance imaging evaluation of biocompatible branched copolymer nanocontrast agents.

PubMed

Jackson, Alexander W; Chandrasekharan, Prashant; Shi, Jian; Rannard, Steven P; Liu, Quan; Yang, Chang-Tong; He, Tao

2015-01-01

Branched copolymer nanoparticles (D(h) =20-35 nm) possessing 1,4,7, 10-tetraazacyclododecane-N,N',N″,N‴-tetraacetic acid macrocycles within their cores have been synthesized and applied as magnetic resonance imaging (MRI) nanosized contrast agents in vivo. These nanoparticles have been generated from novel functional monomers via reversible addition-fragmentation chain transfer polymerization. The process is very robust and synthetically straightforward. Chelation with gadolinium and preliminary in vivo experiments have demonstrated promising characteristics as MRI contrast agents with prolonged blood retention time, good biocompatibility, and an intravascular distribution. The ability of these nanoparticles to perfuse and passively target tumor cells through the enhanced permeability and retention effect is also demonstrated. These novel highly functional nanoparticle platforms have succinimidyl ester-activated benzoate functionalities within their corona, which make them suitable for future peptide conjugation and subsequent active cell-targeted MRI or the conjugation of fluorophores for bimodal imaging. We have also demonstrated that these branched copolymer nanoparticles are able to noncovalently encapsulate hydrophobic guest molecules, which could allow simultaneous bioimaging and drug delivery.

Results from colliding magnetized plasma jet experiments executed at the Trident laser facility

NASA Astrophysics Data System (ADS)

Manuel, M. J.-E.; Rasmus, A. M.; Kurnaz, C. C.; Klein, S. R.; Davis, J. S.; Drake, R. P.; Montgomery, D. S.; Hsu, S. C.; Adams, C. S.; Pollock, B. B.

2015-11-01

The interaction of high-velocity plasma flows in a background magnetic field has applications in pulsed-power and fusion schemes, as well as astrophysical environments, such as accretion systems and stellar mass ejections into the magnetosphere. Experiments recently executed at the Trident Laser Facility at the Los Alamos National Laboratory investigated the effects of an expanding aluminum plasma flow into a uniform 4.5-Tesla magnetic field created using a solenoid designed and manufactured at the University of Michigan. Opposing-target experiments demonstrate interesting collisional behavior between the two magnetized flows. Preliminary interferometry and Faraday rotation measurements will be presented and discussed. This work is funded by the U.S Department of Energy, through the NNSA-DS and SC-OFES Joint Program in High-Energy-Density Laboratory Plasmas, grant number DE-NA0001840. Support for this work was provided by NASA through Einstein Postdoctoral Fellowship grant number PF3-140111 awarded by the Chandra X-ray Center, which is operated by the Astrophysical Observatory for NASA under contract NAS8-03060.

Experiences in teleoperation of land vehicles

NASA Technical Reports Server (NTRS)

Mcgovern, Douglas E.

1989-01-01

Teleoperation of land vehicles allows the removal of the operator from the vehicle to a remote location. This can greatly increase operator safety and comfort in applications such as security patrol or military combat. The cost includes system complexity and reduced system performance. All feedback on vehicle performance and on environmental conditions must pass through sensors, a communications channel, and displays. In particular, this requires vision to be transmitted by close-circuit television with a consequent degradation of information content. Vehicular teleoperation, as a result, places severe demands on the operator. Teleoperated land vehicles have been built and tested by many organizations, including Sandia National Laboratories (SNL). The SNL fleet presently includes eight vehicles of varying capability. These vehicles have been operated using different types of controls, displays, and visual systems. Experimentation studying the effects of vision system characteristics on off-road, remote driving was performed for conditions of fixed camera versus steering-coupled camera and of color versus black and white video display. Additionally, much experience was gained through system demonstrations and hardware development trials. The preliminary experimental findings and the results of the accumulated operational experience are discussed.

Hybrid simulations of weakly collisional plasmas

NASA Astrophysics Data System (ADS)

Xia, Qian; Reville, Brian; Tzoufras, Michail

2016-10-01

Laser produced plasma experiments can be exploited to investigate phenomena of astrophysical relevance. The high densities and velocities that can be generated in the laboratory provide ideal conditions to investigate weakly collisional or collisionless plasma shock physics. In addition, the high temperatures permit magnetic and kinetic Reynolds numbers that are difficult to achieve in other plasma experiments, opening the possibility to study plasma dynamo. Many of these experiments are based on a classic plasma physics problem, namely the interpenetration of two plasma flows. To investigate this phenomenon, we are constructing a novel multi-dimensional hybrid numerical scheme, that solves the ion distribution kinetically via a Vlasov-Fokker-Planck equation, with electrons providing a charge neutralizing fluid. This allows us to follow the evolution on hydrodynamic timescales, while permitting inclusion ofcollisionlesseffects on small scales. It also could be used to study the increasing collisional effects due to the stiff gradient and weakly anisotropic velocity distribution. We present some preliminary validation tests for the code, demonstrating its ability to accurately model key processes that are relevant to laboratory and astrophysical plasmas.

Cherenkov and scintillation light separation on the TheiaR &D experiment

NASA Astrophysics Data System (ADS)

Caravaca, Javier; Land, Benjamin

2016-03-01

Identifying by separate the scintillation and Cherenkov light produced in a scintillation medium enables outstanding capabilities for future particle detectors, being the most relevant: allowing particle directionality information in a low energy threshold detector and improved particle identification. The TheiaR &D experiment uses an array of small and fast photomultipliers (PMTs) and state-of-the-art electronics to demonstrate the reconstruction of a Cherenkov ring in a scintillation medium, based on the number of produced photoelectrons and the timing information. A charged particle ionizing a scintillation medium produces a prompt Cherenkov cone and late isotropic scintillation light, typically delayed by <1ns. The fast response of our PMTs and DAQ provides a precision well below the ns level, making possible the time separation. Furthermore, the usage of the new developed water-based liquid scintillators (WBLS) provides a medium with a tunable Cherenkov/Scintillation light yield ratio, enhancing the visibility of the dimer Cherenkov light in presence of the scintillation light. Description of the experiment, details of the analysis and preliminary results of the first months of running will be discussed.

Adaptive Optical System for Retina Imaging Approaches Clinic Applications

NASA Astrophysics Data System (ADS)

Ling, N.; Zhang, Y.; Rao, X.; Wang, C.; Hu, Y.; Jiang, W.; Jiang, C.

We presented "A small adaptive optical system on table for human retinal imaging" at the 3rd Workshop on Adaptive Optics for Industry and Medicine. In this system, a 19 element small deformable mirror was used as wavefront correction element. High resolution images of photo receptors and capillaries of human retina were obtained. In recent two years, at the base of this system a new adaptive optical system for human retina imaging has been developed. The wavefront correction element is a newly developed 37 element deformable mirror. Some modifications have been adopted for easy operation. Experiments for different imaging wavelengths and axial positions were conducted. Mosaic pictures of photoreceptors and capillaries were obtained. 100 normal and abnormal eyes of different ages have been inspected.The first report in the world concerning the most detailed capillary distribution images cover ±3° by ± 3° field around the fovea has been demonstrated. Some preliminary very early diagnosis experiment has been tried in laboratory. This system is being planned to move to the hospital for clinic experiments.

Current Status and Future Perspectives of the LUCIFER Experiment

DOE PAGES

Beeman, J. W.; Bellini, F.; Benetti, P.; ...

2013-09-30

In the field of fundamental particle physics, the neutrino has become more and more important in the last few years, since the discovery of its mass. In particular, the ultimate nature of the neutrino (if it is a Dirac or a Majorana particle) plays a crucial role not only in neutrino physics, but also in the overall framework of fundamental particle interactions and in cosmology. The only way to disentangle its ultimate nature is to search for the neutrinoless double beta decay. The idea of LUCIFER is to combine the bolometric technique proposed for the CUORE experiment with the bolometricmore » light detection technique used in cryogenic dark matter experiments. The bolometric technique allows an extremely good energy resolution while its combination with the scintillation detection offers an ultimate tool for background rejection. The goal of LUCIFER is not only to build a background-free small-scale experiment but also to directly prove the potentiality of this technique. Preliminary tests on several detectors containing different interesting DBD emitters have clearly demonstrated the excellent background rejection capabilities that arise from the simultaneous, independent, double readout of heat and scintillation light.« less

Rule-governed behavior: teaching a preliminary repertoire of rule-following to children with autism.

PubMed

Tarbox, Jonathan; Zuckerman, Carrie K; Bishop, Michele R; Olive, Melissa L; O'Hora, Denis P

2011-01-01

Rule-governed behavior is generally considered an integral component of complex verbal repertoires but has rarely been the subject of empirical research. In particular, little or no previous research has attempted to establish rule-governed behavior in individuals who do not already display the repertoire. This study consists of two experiments that evaluated multiple exemplar training procedures for teaching a simple component skill, which may be necessary for developing a repertoire of rule-governed behavior. In both experiments, children with autism were taught to respond to simple rules that specified antecedents and the behaviors that should occur in their presence. In the first study, participants were taught to respond to rules containing "if/then" statements, where the antecedent was specified before the behavior. The second experiment was a replication and extension of the first. It involved a variation on the manner in which rules were presented. Both experiments eventually demonstrated generalization to novel rules for all participants; however variations to the standard procedure were required for several participants. Results suggest that rule-following can be analyzed and taught as generalized operant behavior and implications for future research are discussed.

DarkSide-20k: A 20 tonne two-phase LAr TPC for direct dark matter detection at LNGS

NASA Astrophysics Data System (ADS)

Aalseth, C. E.; Acerbi, F.; Agnes, P.; Albuquerque, I. F. M.; Alexander, T.; Alici, A.; Alton, A. K.; Antonioli, P.; Arcelli, S.; Ardito, R.; Arnquist, I. J.; Asner, D. M.; Ave, M.; Back, H. O.; Barrado Olmedo, A. I.; Batignani, G.; Bertoldo, E.; Bettarini, S.; Bisogni, M. G.; Bocci, V.; Bondar, A.; Bonfini, G.; Bonivento, W.; Bossa, M.; Bottino, B.; Boulay, M.; Bunker, R.; Bussino, S.; Buzulutskov, A.; Cadeddu, M.; Cadoni, M.; Caminata, A.; Canci, N.; Candela, A.; Cantini, C.; Caravati, M.; Cariello, M.; Carlini, M.; Carpinelli, M.; Castellani, A.; Catalanotti, S.; Cataudella, V.; Cavalcante, P.; Cavuoti, S.; Cereseto, R.; Chepurnov, A.; Cicalò, C.; Cifarelli, L.; Citterio, M.; Cocco, A. G.; Colocci, M.; Corgiolu, S.; Covone, G.; Crivelli, P.; D'Antone, I.; D'Incecco, M.; D'Urso, D.; Da Rocha Rolo, M. D.; Daniel, M.; Davini, S.; de Candia, A.; De Cecco, S.; De Deo, M.; De Filippis, G.; De Guido, G.; De Rosa, G.; Dellacasa, G.; Della Valle, M.; Demontis, P.; Derbin, A.; Devoto, A.; Di Eusanio, F.; Di Pietro, G.; Dionisi, C.; Dolgov, A.; Dormia, I.; Dussoni, S.; Empl, A.; Fernandez Diaz, M.; Ferri, A.; Filip, C.; Fiorillo, G.; Fomenko, K.; Franco, D.; Froudakis, G. E.; Gabriele, F.; Gabrieli, A.; Galbiati, C.; Garcia Abia, P.; Gendotti, A.; Ghisi, A.; Giagu, S.; Giampa, P.; Gibertoni, G.; Giganti, C.; Giorgi, M. A.; Giovanetti, G. K.; Gligan, M. L.; Gola, A.; Gorchakov, O.; Goretti, A. M.; Granato, F.; Grassi, M.; Grate, J. W.; Grigoriev, G. Y.; Gromov, M.; Guan, M.; Guerra, M. B. B.; Guerzoni, M.; Gulino, M.; Haaland, R. K.; Hallin, A.; Harrop, B.; Hoppe, E. W.; Horikawa, S.; Hosseini, B.; Hughes, D.; Humble, P.; Hungerford, E. V.; Ianni, An.; Jillings, C.; Johnson, T. N.; Keeter, K.; Kendziora, C. L.; Kim, S.; Koh, G.; Korablev, D.; Korga, G.; Kubankin, A.; Kuss, M.; Kuźniak, M.; La Commara, M.; Lehnert, B.; Li, X.; Lissia, M.; Lodi, G. U.; Loer, B.; Longo, G.; Loverre, P.; Lussana, R.; Luzzi, L.; Ma, Y.; Machado, A. A.; Machulin, I. N.; Mandarano, A.; Mapelli, L.; Marcante, M.; Margotti, A.; Mari, S. M.; Mariani, M.; Maricic, J.; Martoff, C. J.; Mascia, M.; Mayer, M.; McDonald, A. B.; Messina, A.; Meyers, P. D.; Milincic, R.; Moggi, A.; Moioli, S.; Monroe, J.; Monte, A.; Morrocchi, M.; Mount, B. J.; Mu, W.; Muratova, V. N.; Murphy, S.; Musico, P.; Nania, R.; Navrer Agasson, A.; Nikulin, I.; Nosov, V.; Nozdrina, A. O.; Nurakhov, N. N.; Oleinik, A.; Oleynikov, V.; Orsini, M.; Ortica, F.; Pagani, L.; Pallavicini, M.; Palmas, S.; Pandola, L.; Pantic, E.; Paoloni, E.; Paternoster, G.; Pavletcov, V.; Pazzona, F.; Peeters, S.; Pelczar, K.; Pellegrini, L. A.; Pelliccia, N.; Perotti, F.; Perruzza, R.; Pesudo, V.; Piemonte, C.; Pilo, F.; Pocar, A.; Pollmann, T.; Portaluppi, D.; Pugachev, D. A.; Qian, H.; Radics, B.; Raffaelli, F.; Ragusa, F.; Razeti, M.; Razeto, A.; Regazzoni, V.; Regenfus, C.; Reinhold, B.; Renshaw, A. L.; Rescigno, M.; Retière, F.; Riffard, Q.; Rivetti, A.; Rizzardini, S.; Romani, A.; Romero, L.; Rossi, B.; Rossi, N.; Rubbia, A.; Sablone, D.; Salatino, P.; Samoylov, O.; Sánchez García, E.; Sands, W.; Sanfilippo, S.; Sant, M.; Santorelli, R.; Savarese, C.; Scapparone, E.; Schlitzer, B.; Scioli, G.; Segreto, E.; Seifert, A.; Semenov, D. A.; Shchagin, A.; Shekhtman, L.; Shemyakina, E.; Sheshukov, A.; Simeone, M.; Singh, P. N.; Skensved, P.; Skorokhvatov, M. D.; Smirnov, O.; Sobrero, G.; Sokolov, A.; Sotnikov, A.; Speziale, F.; Stainforth, R.; Stanford, C.; Suffritti, G. B.; Suvorov, Y.; Tartaglia, R.; Testera, G.; Tonazzo, A.; Tosi, A.; Trinchese, P.; Unzhakov, E. V.; Vacca, A.; Vázquez-Jáuregui, E.; Verducci, M.; Viant, T.; Villa, F.; Vishneva, A.; Vogelaar, B.; Wada, M.; Wahl, J.; Walding, J.; Wang, H.; Wang, Y.; Watson, A. W.; Westerdale, S.; Williams, R.; Wojcik, M. M.; Wu, S.; Xiang, X.; Xiao, X.; Yang, C.; Ye, Z.; Yllera de Llano, A.; Zappa, F.; Zappalà, G.; Zhu, C.; Zichichi, A.; Zullo, M.; Zullo, A.; Zuzel, G.

2018-03-01

Building on the successful experience in operating the DarkSide-50 detector, the DarkSide Collaboration is going to construct DarkSide-20k, a direct WIMP search detector using a two-phase Liquid Argon Time Projection Chamber (LAr TPC) with an active (fiducial) mass of 23 t (20 t). This paper describes a preliminary design for the experiment, in which the DarkSide-20k LAr TPC is deployed within a shield/veto with a spherical Liquid Scintillator Veto (LSV) inside a cylindrical Water Cherenkov Veto (WCV). This preliminary design provides a baseline for the experiment to achieve its physics goals, while further development work will lead to the final optimization of the detector parameters and an eventual technical design. Operation of DarkSide-50 demonstrated a major reduction in the dominant 39Ar background when using argon extracted from an underground source, before applying pulse shape analysis. Data from DarkSide-50, in combination with MC simulation and analytical modeling, shows that a rejection factor for discrimination between electron and nuclear recoils of >3 × 109 is achievable. This, along with the use of the veto system and utilizing silicon photomultipliers in the LAr TPC, are the keys to unlocking the path to large LAr TPC detector masses, while maintaining an experiment in which less than < 0.1 events (other than ν-induced nuclear recoils) is expected to occur within the WIMP search region during the planned exposure. DarkSide-20k will have ultra-low backgrounds than can be measured in situ, giving sensitivity to WIMP-nucleon cross sections of 1.2 × 10^{-47} cm2 (1.1 × 10^{-46} cm2) for WIMPs of 1 TeV/c 2 (10 TeV/c 2) mass, to be achieved during a 5 yr run producing an exposure of 100 t yr free from any instrumental background.

The Viking biological investigation - Preliminary results

NASA Technical Reports Server (NTRS)

Klein, H. P.; Oyama, V. I.; Berdahl, B. J.; Horowitz, N. H.; Hobby, G. L.; Levin, G. V.; Straat, P. A.; Lederberg, J.; Rich, A.; Hubbard, J. S.

1976-01-01

A preliminary progress report is presented for the Viking biological investigation through its first month. The carbon assimilation, gas exchange, and labeled release experiments are described in detail, and the chronology of the experiments is outlined. For the first experiment, it is found that a small amount of gas was converted into organic material in one sample and that heat treatment of a duplicate sample prevented such conversion. In the second experiment, a substantial amount of O2 was detected along with significant increases in CO2 and small changes in N2. In the third experiment, a significant amount of radioactive gas was evolved from one sample, but not from a duplicate heat-treated sample. Possible biological and nonbiological interpretations are considered for these results. It is concluded that while the experiments provide clear evidence for the occurrence of chemical reactions and while the results do not violate any prima facie criteria for biological processes, a definitive answer cannot yet be given to the question of whether life exists on Mars.

A preliminary discussion of gravitational physics experiments for the Spacelab era

NASA Technical Reports Server (NTRS)

Decher, R.; Winkler, C. G.

1976-01-01

An overview of past, present, and proposed future experiments in gravitational physics is given. These experiments are concerned with the measurement of relativistic gravity effects to test theories of gravitation. Certain experiments which could be performed on shuttle and Spacelab missions and the potential of Spacelab for gravitation physics research are discussed.

Preliminary experiments to quantify liquid movement under mimetic vocal fold vibrational forces.

PubMed

Titze, Ingo R; Klemuk, Sarah; Lu, Xiaoying

2014-07-01

Hydration of vocal fold tissues is essential for self-sustained oscillation. Normal regulatory processes of liquid transport to and from the vocal folds would be expected through the autonomic systems, but the possibility exists that liquid movement may occur locally due to vibrational pressures. Such movement may cause regions of lower or higher concentrations of liquid viscosity and therewith changes in phonation threshold pressure. Hyaluronic acid, a glycosaminoglycan that attracts large quantities of free water, may be a key molecule for transporting or localizing liquids. Some preliminary experiments are reported in which attempts were made to move low-concentration HA liquids with vibration. None of the experiments was conclusive, but collectively they lay some groundwork for future explorations.

Astrionic system optimization and modular astrionics for NASA missions after 1974. Preliminary definition of astrionic system for space tug Mission Vehicle Payload (MVP)

NASA Technical Reports Server (NTRS)

1970-01-01

Results of preliminary studies to define the space tug astrionic system, subsystems, and components to meet requirements for a variety of missions are reported. Emphasis is placed on demonstration of the modular astrionics approach in the design of the space tug astrionic system.

EXECUTIVE SUMMARY FOR FULL-SCALE DUAL-ALKALI DEMONSTRATION AT LOUISVILLE GAS AND ELECTRIC CO. - PRELIMINARY DESIGN AND COST ESTIMATE

EPA Science Inventory

The report is the executive summary for the preliminary design of the dual-alkali system, designed by Combustion Equipment Associates, Inc./Arthur D. Little, Inc. and being installed to control SO2 emissions from Louisville Gas and Electric Company's Cane Run Unit No. 6 boiler. T...

Japanese Manga in Translation and American Graphic Novels: A Preliminary Examination of the Collections in 44 Academic Libraries

ERIC Educational Resources Information Center

Masuchika, Glenn; Boldt, Gail

2010-01-01

American graphic novels are increasingly recognized as high-quality literature and an interesting genre for academic study. Graphic novels of Japan, called manga, have established a strong foothold in American culture. This preliminary survey of 44 United States university libraries demonstrates that Japanese manga in translation are consistently…

Development and Preliminary Evaluation of a One-Week Summer Treatment Program for Separation Anxiety Disorder

ERIC Educational Resources Information Center

Santucci, Lauren C.; Ehrenreich, Jill T.; Trosper, Sarah E.; Bennett, Shannon M.; Pincus, Donna B.

2009-01-01

Numerous clinical trials have demonstrated the efficacy of cognitive behavior therapy (CBT) for the treatment of childhood Separation Anxiety Disorder (SAD) and other anxiety disorders yet additional research may still be needed to better access and engage anxious youth. In this study, we investigated the acceptability and preliminary utility of a…

Preliminary Evaluation Report on the Los Angeles City Schools, SB 28 Demonstration Program in Mathematics.

ERIC Educational Resources Information Center

Gordon, C. Wayne

The purpose of this preliminary report is to describe and evaluate the Los Angeles Model Mathematics Project (LAMMP). The objectives of this project include the improvement of mathematical skills and understanding of mathematical concepts, the improvement of students' self-image, the development of instructional materials and the assessment of…

76 FR 56147 - Certain Steel Nails From the People's Republic of China: Preliminary Results and Preliminary...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-12

... electroplating or hot dipping one or more times), phosphate cement, and paint. Head styles include, but are not... control and thus should be assessed a single antidumping duty rate.\\28\\ Exporters can demonstrate this independence through the absence of both de jure and de facto government control over export activities. Id...

Preliminary Report of NRC Twin Otter Operations in the 1997 Southern Great Plains Experiment

NASA Technical Reports Server (NTRS)

MacPherson, J. Ian

1997-01-01

From June 18 to July 17, 1997, the NRC Twin Otter atmospheric research aircraft was operated from Oklahoma City, U.S.A., in the Southern Great Plains 1997 (SGP97) Hydrology Experiment. The primary role of the aircraft was to measure the vertical fluxes of sensible and latent heat, CO2, ozone and momentum in the atmospheric boundary layer, along with supporting meteorological and radiometric data. Approximately 400 flux runs and 100 soundings were flown in 27 project flights over rural areas near Oklahoma City. This preliminary report documents the flight program, lists the instrumentation aboard the aircraft, and presents a summary of run-averaged data from each flux run. These data are from the in-field analysis and must be considered preliminary. A re-analysis incorporating updated calibrations is planned for the fall of 1997 followed by a more comprehensive technical report.

Chemical Analysis of the Moon at the Surveyor VII Landing Site: Preliminary Results.

PubMed

Turkevich, A L; Franzgrote, E J; Patterson, J H

1968-10-04

The alpha-scattering experiment aboard Surveyor VII has provided a chemical analysis of the moon in the area of the crater Tycho. The preliminary results indicate a chemical composition similar to that already found at two mare sites, but with a lower concentration of elements of the iron group (titanium through copper).

Preliminary Analysis of Fluctuations in the Received Uplink-Beacon-Power Data Obtained From the GOLD Experiments

NASA Technical Reports Server (NTRS)

Jeganathan, M.; Wilson, K. E.; Lesh, J. R.

1996-01-01

Uplink data from recent free-space optical communication experiments carried out between the Table Mountain Facility and the Japanese Engineering Test Satellite are used to study fluctuations caused by beam propagation through the atmosphere. The influence of atmospheric scintillation, beam wander and jitter, and multiple uplink beams on the statistics of power received by the satellite is analyzed and compared to experimental data. Preliminary analysis indicates the received signal obeys an approximate lognormal distribution, as predicted by the weak-turbulence model, but further characterization of other sources of fluctuations is necessary for accurate link predictions.

Preliminary analysis of fluctuations in the received uplink-beacon-power data obtained from the GOLD experiments

NASA Technical Reports Server (NTRS)

Jeganathan, M.; Wilson, K. E.; Lesh, J. R.

1996-01-01

Uplink data from recent free-space optical communication experiments carried out between the Table Mountain Facility and the Japanese Engineering Test Satellite are used to study fluctuations caused by beam propagation through the atmosphere. The influence of atmospheric scintillation, beam wander and jitter, and multiple uplink beams on the statistics of power received by the satellite is analyzed and compared to experimental data. Preliminary analysis indicates the received signal obeys an approximate lognormal distribution, as predicted by the weak-turbulence model, but further characterization of other sources of fluctuations is necessary for accurate link predictions.

Preliminary developments of MTR plates with uranium nitride

DOE Office of Scientific and Technical Information (OSTI.GOV)

Durand, J.P.; Laudamy, P.; Richter, K.

1997-08-01

In the opinion of CERCA, the total weight of Uranium per MTR plate (without changing the external dimensions) cannot be further increased using U{sub 3}Si{sub 2}. Limits have been reached on plates with a thicker meat or loaded to 6g Ut/cm{sup 3}. The use of a denser fuel like Uranium mononitride could permit an increase in these limits. A collaboration between the Institute for Transuranium Elements (ITU), Joint Research Centre of the European Commission, and CERCA has been set ut. The preliminary studies at the ITU to check compatibility between aluminium and UN proved that there are no metallurgical interactionsmore » below 500{degrees}C. Feasibility of the manufacturing, on a laboratory scale at CERCA, of depleted Uranium mononitride plates loaded to 7 g Ut/cm{sup 3} has been demonstrated. The manufacturing process, however, is only one aspect of the development of a new fuel. The experience gained in the case of U{sub 3}Si{sub 2} has shown that the development of a new fuel requires considerable time and financial investment. Such a development certainly represents an effort of about 10 years.« less

Inquiry experiences as a lecture supplement for preservice elementary teachers and general education students

NASA Astrophysics Data System (ADS)

Marshall, Jill A.; Dorward, James T.

2000-07-01

The study reported here was designed to substantiate the findings of previous research on the use of inquiry-based laboratory activities in introductory college physics courses. The authors sought to determine whether limited use of inquiry activities as a supplement to a traditional lecture and demonstration curriculum would improve student achievement in introductory classes for preservice teachers and general education students. Achievement was measured by responses to problems designed to test conceptual understanding as well as overall course grades. We analyzed the effect on selected student outcome measures in a preliminary study in which some students engaged in inquiry activities and others did not, and interviewed students about their perceptions of the inquiry activities. In the preliminary study, preservice elementary teachers and female students showed significantly higher achievement after engaging such activities, but only on exam questions relating directly to the material covered in the exercises. In a second study we used a common exam problem to compare the performance of students who had engaged in a revised version of the inquiry activities with the performance of students in algebra and calculus-based classes. The students who had engaged in inquiry investigations significantly outperformed the other students.

Development of a rapid diagnostic test for pertussis: direct detection of pertussis toxin in respiratory secretions.

PubMed Central

Friedman, R L; Paulaitis, S; McMillan, J W

1989-01-01

Monoclonal antibodies (MAb) were produced against the specific Bordetella pertussis antigen pertussis toxin (PT). In preliminary studies, one MAb (IB12) was selected and used in an enzyme-linked dot blot immunoassay to evaluate the ability of the method to detect known amounts of PT in control experiments and to test its potential for direct detection of PT in nasopharyngeal secretion (NP) specimens from patients with confirmed cases of whooping cough. The dot blot assay was able to detect PT at levels as low as 10 ng per dot in either buffer or control NP specimens. The assay demonstrated specificity, reacting only with dot blots of whole B. pertussis and not Bordetella bronchiseptica, Bordetella parapertussis, or other bacterial strains. In preliminary studies, NP aspirate, swab, and wash specimens were compared. The specimen of choice was found to be the NP aspirate, for which 100% positive results were found in the assay. These initial studies suggest that the dot blot immunoassay in which a MAb is used for direct detection of PT in NP specimens may be useful as a rapid diagnostic test for pertussis. Images PMID:2808670

Multiphase Flow Technology Impacts on Thermal Control Systems for Exploration

NASA Technical Reports Server (NTRS)

McQuillen, John; Sankovic, John; Lekan, Jack

2006-01-01

The Two-Phase Flow Facility (TPHIFFy) Project focused on bridging the critical knowledge gap by developing and demonstrating critical multiphase fluid products for advanced life support, thermal management and power conversion systems that are required to enable the Vision for Space Exploration. Safety and reliability of future systems will be enhanced by addressing critical microgravity fluid physics issues associated with flow boiling, condensation, phase separation, and system stability. The project included concept development, normal gravity testing, and reduced gravity aircraft flight campaigns, in preparation for the development of a space flight experiment implementation. Data will be utilized to develop predictive models that could be used for system design and operation. A single fluid, two-phase closed thermodynamic loop test bed was designed, assembled and tested. The major components in this test bed include: a boiler, a condenser, a phase separator and a circulating pump. The test loop was instrumented with flow meters, thermocouples, pressure transducers and both high speed and normal speed video cameras. A low boiling point surrogate fluid, FC-72, was selected based on scaling analyses using preliminary designs for operational systems. Preliminary results are presented which include flow regime transitions and some observations regarding system stability.

A Method for the Control of Multigrasp Myoelectric Prosthetic Hands

PubMed Central

Dalley, Skyler Ashton; Varol, Huseyin Atakan; Goldfarb, Michael

2012-01-01

This paper presents the design and preliminary experimental validation of a multigrasp myoelectric controller. The described method enables direct and proportional control of multigrasp prosthetic hand motion among nine characteristic postures using two surface electromyography electrodes. To assess the efficacy of the control method, five nonamputee subjects utilized the multigrasp myoelectric controller to command the motion of a virtual prosthesis between random sequences of target hand postures in a series of experimental trials. For comparison, the same subjects also utilized a data glove, worn on their native hand, to command the motion of the virtual prosthesis for similar sequences of target postures during each trial. The time required to transition from posture to posture and the percentage of correctly completed transitions were evaluated to characterize the ability to control the virtual prosthesis using each method. The average overall transition times across all subjects were found to be 1.49 and 0.81 s for the multigrasp myoelectric controller and the native hand, respectively. The average transition completion rates for both were found to be the same (99.2%). Supplemental videos demonstrate the virtual prosthesis experiments, as well as a preliminary hardware implementation. PMID:22180515

Preliminary measurements of the edge magnetic field pitch from 2-D Doppler backscattering in MAST and NSTX-U (invited)

DOE PAGES

Vann, R. G. L.; Brunner, K. J.; Ellis, R.; ...

2016-09-13

The Synthetic Aperture Microwave Imaging (SAMI) system is a novel diagnostic consisting of an array of 8 independently phased antennas. At any one time, SAMI operates at one of the 16 frequencies in the range 10-34.5 GHz. The imaging beam is steered in software post-shot to create a picture of the entire emission surface. In SAMI’s active probing mode of operation, the plasma edge is illuminated with a monochromatic source and SAMI reconstructs an image of the Doppler back-scattered (DBS) signal. By assuming that density fluctuations are extended along magnetic field lines, and knowing that the strongest back-scattered signals aremore » directed perpendicular to the density fluctuations, SAMI’s 2-D DBS imaging capability can be used to measure the pitch of the edge magnetic field. In this paper, we present preliminary pitch angle measurements obtained by SAMI on the Mega Amp Spherical Tokamak (MAST) at Culham Centre for Fusion Energy and on the National Spherical Torus Experiment Upgrade at Princeton Plasma Physics Laboratory. Lastly, the results demonstrate encouraging agreement between SAMI and other independent measurements.« less

Bringing computational science to the public.

PubMed

McDonagh, James L; Barker, Daniel; Alderson, Rosanna G

2016-01-01

The increasing use of computers in science allows for the scientific analyses of large datasets at an increasing pace. We provided examples and interactive demonstrations at Dundee Science Centre as part of the 2015 Women in Science festival, to present aspects of computational science to the general public. We used low-cost Raspberry Pi computers to provide hands on experience in computer programming and demonstrated the application of computers to biology. Computer games were used as a means to introduce computers to younger visitors. The success of the event was evaluated by voluntary feedback forms completed by visitors, in conjunction with our own self-evaluation. This work builds on the original work of the 4273π bioinformatics education program of Barker et al. (2013, BMC Bioinform. 14:243). 4273π provides open source education materials in bioinformatics. This work looks at the potential to adapt similar materials for public engagement events. It appears, at least in our small sample of visitors (n = 13), that basic computational science can be conveyed to people of all ages by means of interactive demonstrations. Children as young as five were able to successfully edit simple computer programs with supervision. This was, in many cases, their first experience of computer programming. The feedback is predominantly positive, showing strong support for improving computational science education, but also included suggestions for improvement. Our conclusions are necessarily preliminary. However, feedback forms suggest methods were generally well received among the participants; "Easy to follow. Clear explanation" and "Very easy. Demonstrators were very informative." Our event, held at a local Science Centre in Dundee, demonstrates that computer games and programming activities suitable for young children can be performed alongside a more specialised and applied introduction to computational science for older visitors.

Design, construction, and testing of the direct absorption receiver panel research experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chavez, J.M.; Rush, E.E.; Matthews, C.W.

1990-01-01

A panel research experiment (PRE) was designed, built, and tested as a scaled-down model of a direct absorption receiver (DAR). The PRE is a 3-MW{sub t}DAR experiment that will allow flow testing with molten nitrate salt and provide a test bed for DAR testing with actual solar heating. In a solar central receiver system DAR, the heat absorbing fluid (a blackened molten nitrate salt) flows in a thin film down a vertical panel (rather than through tubes as in conventional receiver designs) and absorbs the concentrated solar flux directly. The ability of the flowing salt film to absorb flux directly.more » The ability of the flowing salt film to absorb the incident solar flux depends on the panel design, hydraulic and thermal fluid flow characteristics, and fluid blackener properties. Testing of the PRE is being conducted to demonstrate the engineering feasibility of the DAR concept. The DAR concept is being investigated because it offers numerous potential performance and economic advantages for production of electricity when compared to other solar receiver designs. The PRE utilized a 1-m wide by 6-m long absorber panel. The salt flow tests are being used to investigate component performance, panel deformations, and fluid stability. Salt flow testing has demonstrated that all the DAR components work as designed and that there are fluid stability issues that need to be addressed. Future solar testing will include steady-state and transient experiments, thermal loss measurements, responses to severe flux and temperature gradients and determination of peak flux capability, and optimized operation. In this paper, we describe the design, construction, and some preliminary flow test results of the Panel Research Experiment. 11 refs., 8 figs., 2 tabs.« less

Motivation for proposed experimentation in the realm of accelerated E. M. systems: A preliminary design for an experiment

NASA Technical Reports Server (NTRS)

Post, E. J.

1970-01-01

An experiment, designed to determine the difference between fields-magnetic and electric-surrounding a uniformly moving charge as contrasted with the fields surrounding an accelerated charge, is presented. A thought experiment is presented to illustrate the process.

General characteristics of preliminary data processing in the Copernicus experiment

NASA Technical Reports Server (NTRS)

Ziolkovski, K.; Kossatski, K.

1975-01-01

Data from the 'Copernicus' experiment is processed in four stages: setting up of basic arrays, data calibration, graphical display of results, and assignment of results to navigation parameters. Each stage is briefly discussed.

Three-dimensional dynamics of temperature fields in phantoms and biotissue under IR laser photothermal therapy using gold nanoparticles and ICG dye

NASA Astrophysics Data System (ADS)

Akchurin, Georgy G.; Garif, Akchurin G.; Maksimova, Irina L.; Skaptsov, Alexander A.; Terentyuk, Georgy S.; Khlebtsov, Boris N.; Khlebtsov, Nikolai G.; Tuchin, Valery V.

2010-02-01

We describe applications of silica (core)/gold (shell) nanoparticles and ICG dye to photothermal treatment of phantoms, biotissue and spontaneous tumor of cats and dogs. The laser irradiation parameters were optimized by preliminary experiments with laboratory rats. Three dimensional dynamics of temperature fields in tissue and solution samples was measured with a thermal imaging system. It is shown that the temperature in the volume region of nanoparticles localization can substantially exceed the surface temperature recorded by the thermal imaging system. We have demonstrated effective optical destruction of cancer cells by local injection of plasmon-resonant gold nanoshells and ICG dye followed by continuous wave (CW) diode laser irradiation at wavelength 808 nm.

The propagation and backscattering of soliton-like pulses in a chain of quartz beads and related problems. (II). Backscattering

NASA Astrophysics Data System (ADS)

Manciu, Marian; Sen, Surajit; Hurd, Alan J.

1999-12-01

We demonstrate that the propagation of solitons, soliton-like excitations and acoustic pulses discussed in the preceding article (M. Manciu, S. Sen and A.J. Hurd, Physica A, preceding article) can be used to detect buried impurities in a chain of elastic grains with Hertzian contacts. We also present preliminary data for 3D granular beds, where soliton-like objects can form and can be used to probe for buried impurities, thus suggesting that soliton-pulse spectroscopy has the potential to become a valuable tool for probing the structural properties of granular assemblies. The effects of restitution are briefly discussed. We refer to available experiments which support our contention.

Core-shell poly-methylmethacrylate nanoparticles as effective carriers of electrostatically loaded anionic porphyrin.

PubMed

Varchi, Greta; Benfenati, Valentina; Pistone, Assunta; Ballestri, Marco; Sotgiu, Giovanna; Guerrini, Andrea; Dambruoso, Paolo; Liscio, Andrea; Ventura, Barbara

2013-05-01

Among the medical applications of nanoparticles, their usage as photosensitizer (PS) carriers for photodynamic therapy (PDT) has attracted increasing attention. In the present study we explored the morphological and photophysical properties of core-shell PMMA nanoparticles (PMMA-NPs) electrostatically post-loaded with the synthetic, water soluble 5,10,15,20-tetrakis(4-sulphonatophenyl)-porphyrin (TPPS4). pH response and singlet oxygen analyses of differently loaded samples proved the high capability of the PMMA-NPs to shield the PS from the environment, while retaining the PS singlet oxygen production capability. Preliminary in vitro imaging and phototoxicity experiments on HepG2 cells demonstrated the efficacy of the system to trigger photoinduced cell death in the culture.

Microbial response to space environment, part B

NASA Technical Reports Server (NTRS)

Taylor, G. R.; Chassay, C. E.; Ellis, W. L.; Foster, B. G.; Volz, P. A.; Spizizen, J.; Buecker, H.; Wrenn, R. T.; Simmonds, R. C.; Long, R. A.

1972-01-01

The performance of the microbial response to space environment experiment is considered excellent by all investigators. For most microbial systems, only preliminary survival data are available at this time. None of the available data indicate space flight-mediated changes in cell viability or recovery. One quite important observation has been made at this early date, however. The eggs produced after mice had been infected with N. dubius larvae demonstrated a significant decrease in hatchability when compared to identical ground controls. Except for the fact that the Apollo 16 flight larvae had been on board the command module, treatment of the flown larvae and ground control larvae was the same; neither had been exposed to UV irradiation. The significance and implications of this finding are currently being studied.

RRM3 Fluid Management Device

NASA Technical Reports Server (NTRS)

Barfknecht, P.; Benson, D.; Boyle, R.; DeLee, C.; DiPirro, M.; Francis, J.; Li, X.; McGuire, J.; Mustafi, S.; Tuttle, J.;

Telepathology between Richmond and Beckley Veterans Affairs Hospitals: report on the first 1000 cases.

PubMed

Weisz-Carrington, P; Blount, M; Kipreos, B; Mohanty, L; Lippman, R; Todd, W M; Trent, B

1999-01-01

A telepathology connection between Richmond VAMC and Beckley VAMC using dynamic robotic telepathology to provide pathology services remotely was established. This study reports a 14-month experience using telepathology to diagnose surgical specimens obtained from patients at the Beckley VA Medical Center and viewed in Richmond 250 miles away. Over 14 months, 2325 slides representing 1000 cases were viewed. Discrepancies were observed in 20 of 2325 slides, or 0.86% of the total. None of the patients, where a discrepancy was found, were adversely affected by the preliminary report given. This study demonstrates that telepathology is a reliable and cost-effective alternative to on-site pathology services and reviews advantages and disadvantages of the system.

Experimental investigation of refractory metals in the premelting region during fast heating

NASA Astrophysics Data System (ADS)

Senchenko, V. N.; Belikov, R. S.; Popov, V. S.

2015-11-01

This work demonstrates experimental possibility of investigation of high refractory materials around its melting point, particularly in premelting region with high accuracy. In this article authors describe the developed experimental setup based on rapid resistive self-heating of a sample by a large current pulse generated by a capacitor discharge circuit that allow fast pulse interruption by temperature feedback signal. The sample temperature was measured with a two-channel microsecond radiation pyrometer. Preliminary experiments were conducted on tantalum and molybdenum at heating speed of 108 K/s. The method allows investigating thermophysical properties of refractory conductive materials such as melting temperature, melting heat, specific resistivity, specific enthalpy and specific heat capacity in solid and liquid phase, especially in premelting area.

The Utility of Reflective Writing after a Palliative Care Experience: Can We Assess Medical Students' Professionalism?

PubMed Central

Gill, Anne C.; Teal, Cayla R.; Morrison, Laura J.

2013-01-01

Abstract Background Medical education leaders have called for a curriculum that proactively teaches knowledge, skills, and attitudes required for professional practice and have identified professionalism as a competency domain for medical students. Exposure to palliative care (PC), an often deeply moving clinical experience, is an optimal trigger for rich student reflection, and students' reflective writings can be explored for professional attitudes. Objective Our aim was to evaluate the merit of using student reflective writing about a PC clinical experience to teach and assess professionalism. Methods After a PC patient visit, students wrote a brief reflective essay. We explored qualitatively if/how evidence of students' professionalism was reflected in their writing. Five essays were randomly chosen to develop a preliminary thematic structure, which then guided analysis of 30 additional, randomly chosen essays. Analysts coded transcripts independently, then collaboratively, developed thematic categories, and selected illustrative quotes for each theme and subtheme. Results Essays revealed content reflecting more rich information about students' progress toward achieving two professionalism competencies (demonstrating awareness of one's own perspectives and biases; demonstrating caring, compassion, empathy, and respect) than two others (displaying self-awareness of performance; recognizing and taking actions to correct deficiencies in one's own behavior, knowledge, and skill). Conclusions Professional attitudes were evident in all essays. The essays had limited use for formal summative assessment of professionalism competencies. However, given the increasing presence of PC clinical experiences at medical schools nationwide, we believe this assessment strategy for professionalism has merit and deserves further investigation. PMID:23937062

Near-Death Experiences and the "Fantasy-Prone" Personality: Preliminary Findings.

ERIC Educational Resources Information Center

Council, James R.; Greyson, Bruce

Near-death experiences (NDEs) are subjective experiences at the threshold of death which can include strong positive affect, dissociation from the physical body, and paranormal/transcendental phenomena. Empirical investigation of NDEs has typically relied upon retrospective reports and personality studies of individuals who have come close to…

Do surrounding figures' emotions affect judgment of the target figure's emotion? Comparing the eye-movement patterns of European Canadians, Asian Canadians, Asian international students, and Japanese.

PubMed

Masuda, Takahiko; Wang, Huaitang; Ishii, Keiko; Ito, Kenichi

2012-01-01

Although the effect of context on cognition is observable across cultures, preliminary findings suggest that when asked to judge the emotion of a target model's facial expression, East Asians are more likely than their North American counterparts to be influenced by the facial expressions of surrounding others (Masuda et al., 2008b). Cultural psychologists discuss this cultural variation in affective emotional context under the rubric of holistic vs. analytic thought, independent vs. interdependent self-construals, and socially disengaged vs. socially engaged emotion (e.g., Mesquita and Markus, 2004). We demonstrate that this effect is generalizable even when (1) photos of real facial emotions are used, (2) the saliency of the target model's emotion is attenuated, and (3) a specific amount of observation time is allocated. We further demonstrate that the experience plays an important role in producing cultural variations in the affective context effect on cognition.

Melanopsin-expressing retinal ganglion cells are resistant to cell injury, but not always.

PubMed

Georg, Birgitte; Ghelli, Anna; Giordano, Carla; Ross-Cisneros, Fred N; Sadun, Alfredo A; Carelli, Valerio; Hannibal, Jens; La Morgia, Chiara

2017-09-01

Melanopsin retinal ganglion cells (mRGCs) are intrinsically photosensitive RGCs deputed to non-image forming functions of the eye such as synchronization of circadian rhythms to light-dark cycle. These cells are characterized by unique electrophysiological, anatomical and biochemical properties and are usually more resistant than conventional RGCs to different insults, such as axotomy and different paradigms of stress. We also demonstrated that these cells are relatively spared compared to conventional RGCs in mitochondrial optic neuropathies (Leber's hereditary optic neuropathy and Dominant Optic Atrophy). However, these cells are affected in other neurodegenerative conditions, such as glaucoma and Alzheimer's disease. We here review the current evidences that may underlie this dichotomy. We also present our unpublished data on cell experiments demonstrating that melanopsin itself does not explain the robustness of these cells and some preliminary data on immunohistochemical assessment of mitochondria in mRGCs. Copyright © 2017 Elsevier B.V. and Mitochondria Research Society. All rights reserved.

Knowledge-based approach to video content classification

NASA Astrophysics Data System (ADS)

Chen, Yu; Wong, Edward K.

2001-01-01

A framework for video content classification using a knowledge-based approach is herein proposed. This approach is motivated by the fact that videos are rich in semantic contents, which can best be interpreted and analyzed by human experts. We demonstrate the concept by implementing a prototype video classification system using the rule-based programming language CLIPS 6.05. Knowledge for video classification is encoded as a set of rules in the rule base. The left-hand-sides of rules contain high level and low level features, while the right-hand-sides of rules contain intermediate results or conclusions. Our current implementation includes features computed from motion, color, and text extracted from video frames. Our current rule set allows us to classify input video into one of five classes: news, weather, reporting, commercial, basketball and football. We use MYCIN's inexact reasoning method for combining evidences, and to handle the uncertainties in the features and in the classification results. We obtained good results in a preliminary experiment, and it demonstrated the validity of the proposed approach.

Knowledge-based approach to video content classification

NASA Astrophysics Data System (ADS)

Chen, Yu; Wong, Edward K.

2000-12-01

A framework for video content classification using a knowledge-based approach is herein proposed. This approach is motivated by the fact that videos are rich in semantic contents, which can best be interpreted and analyzed by human experts. We demonstrate the concept by implementing a prototype video classification system using the rule-based programming language CLIPS 6.05. Knowledge for video classification is encoded as a set of rules in the rule base. The left-hand-sides of rules contain high level and low level features, while the right-hand-sides of rules contain intermediate results or conclusions. Our current implementation includes features computed from motion, color, and text extracted from video frames. Our current rule set allows us to classify input video into one of five classes: news, weather, reporting, commercial, basketball and football. We use MYCIN's inexact reasoning method for combining evidences, and to handle the uncertainties in the features and in the classification results. We obtained good results in a preliminary experiment, and it demonstrated the validity of the proposed approach.

Imaging at an x-ray absorption edge using free electron laser pulses for interface dynamics in high energy density systems [Resonant phase contrast imaging for interface physics

DOE PAGES

Beckwith, M. A.; Jiang, S.; Schropp, A.; ...

2017-05-01

Tuning the energy of an x-ray probe to an absorption line or edge can provide material-specific measurements that are particularly useful for interfaces. Simulated hard x-ray images above the Fe K-edge are presented to examine ion diffusion across an interface between Fe 2O 3 and SiO 2 aerogel foam materials. The simulations demonstrate the feasibility of such a technique for measurements of density scale lengths near the interface with submicron spatial resolution. A proof-of-principle experiment is designed and performed at the Linac coherent light source facility. Preliminary data show the change of the interface after shock compression and heating withmore » simultaneous fluorescence spectra for temperature determination. Here, the results provide the first demonstration of using x-ray imaging at an absorption edge as a diagnostic to detect ultrafast phenomena for interface physics in high-energy-density systems.« less

Design and characterization of biofunctional magnetic porous silicon flakes.

PubMed

Muñoz Noval, A; García, R; Ruiz Casas, D; Losada Bayo, D; Sánchez Vaquero, V; Torres Costa, V; Martín Palma, R J; García, M A; García Ruiz, J P; Serrano Olmedo, J J; Muñoz Negrete, J F; del Pozo Guerrero, F; Manso Silván, M

2013-04-01

Magnetic porous silicon flakes (MPSF) were obtained from mesoporous silicon layers formed by multi-step anodization and subsequent composite formation with Fe oxide nanoparticles by thermal annealing. The magnetic nanoparticles adhered to the surface and penetrated inside the pores. Their structure evolved as a result of the annealing treatments derived from X-ray diffraction and X-ray absorption analyses. Moreover, by tailoring the magnetic load, the dynamic and hydrodynamic properties of the particles were controlled, as observed by the pressure displayed against a sensor probe. Preliminary functionality experiments were performed using an eye model, seeking potential use of MPSF as reinforcement for restored detached retina. It was observed that optimal flake immobilization is obtained when the MPSF reach values of magnetic saturation >10(-4)Am(2)g(-1). Furthermore, the MPSF were demonstrated to be preliminarily biocompatible in vitro. Moreover, New Zealand rabbit in vivo models demonstrated their short-term histocompatibility and their magnetic functionality as retina pressure actuators. Copyright © 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

A prototype experiment for cooperative monitoring of nuclear reactors with cubic meter scale antineutrino detectors

NASA Astrophysics Data System (ADS)

Bernstein, A.; Allen, M.; Bowden, N.; Brennan, J.; Carr, D. J.; Estrada, J.; Hagmann, C.; Lund, J. C.; Madden, N. W.; Winant, C. D.

2005-09-01

Our Lawrence Livermore National Laboratory/Sandia National Laboratories collaboration has deployed a cubic-meter-scale antineutrino detector to demonstrate non-intrusive and automatic monitoring of the power levels and plutonium content of a nuclear reactor. Reactor monitoring of this kind is required for all non-nuclear weapons states under the Nuclear Nonproliferation Treaty (NPT), and is implemented by the International Atomic Energy Agency (IAEA). Since the antineutrino count rate and energy spectrum depend on the relative yields of fissioning isotopes in the reactor core, changes in isotopic composition can be observed without ever directly accessing the core. Data from a cubic meter scale antineutrino detector, coupled with the well-understood principles that govern the core's evolution in time, can be used to determine whether the reactor is being operated in an illegitimate way. Our group has deployed a detector at the San Onofre reactor site in California to demonstrate this concept. This paper describes the concept and shows preliminary results from 8 months of operation.

Computational Analysis of the G-III Laminar Flow Glove

NASA Technical Reports Server (NTRS)

Malik, Mujeeb R.; Liao, Wei; Lee-Rausch, Elizabeth M.; Li, Fei; Choudhari, Meelan M.; Chang, Chau-Lyan

2011-01-01

Under NASA's Environmentally Responsible Aviation Project, flight experiments are planned with the primary objective of demonstrating the Discrete Roughness Elements (DRE) technology for passive laminar flow control at chord Reynolds numbers relevant to transport aircraft. In this paper, we present a preliminary computational assessment of the Gulfstream-III (G-III) aircraft wing-glove designed to attain natural laminar flow for the leading-edge sweep angle of 34.6deg. Analysis for a flight Mach number of 0.75 shows that it should be possible to achieve natural laminar flow for twice the transition Reynolds number ever achieved at this sweep angle. However, the wing-glove needs to be redesigned to effectively demonstrate passive laminar flow control using DREs. As a by-product of the computational assessment, effect of surface curvature on stationary crossflow disturbances is found to be strongly stabilizing for the current design, and it is suggested that convex surface curvature could be used as a control parameter for natural laminar flow design, provided transition occurs via stationary crossflow disturbances.

Use of Docker for deployment and testing of astronomy software

NASA Astrophysics Data System (ADS)

Morris, D.; Voutsinas, S.; Hambly, N. C.; Mann, R. G.

2017-07-01

We describe preliminary investigations of using Docker for the deployment and testing of astronomy software. Docker is a relatively new containerization technology that is developing rapidly and being adopted across a range of domains. It is based upon virtualization at operating system level, which presents many advantages in comparison to the more traditional hardware virtualization that underpins most cloud computing infrastructure today. A particular strength of Docker is its simple format for describing and managing software containers, which has benefits for software developers, system administrators and end users. We report on our experiences from two projects - a simple activity to demonstrate how Docker works, and a more elaborate set of services that demonstrates more of its capabilities and what they can achieve within an astronomical context - and include an account of how we solved problems through interaction with Docker's very active open source development community, which is currently the key to the most effective use of this rapidly-changing technology.

Metabolic response of granulocytes and platelets to synthetic vascular grafts: preliminary results with an in vitro technique.

PubMed

Pärsson, H; Nässberger, L; Thörne, J; Norgren, L

1995-04-01

The metabolism of granulocytes as well as platelets evoked by incubation with different synthetic vascular grafts was monitored during 6-h batch experiments using microcalorimetry. Standard knitted Dacron grafts, ePTFE-grafts, knitted Dacron grafts with collagen impregnation, and knitted Dacron grafts with external collagen-coating were used. The heat production per cell was calculated. A rapid increase of metabolic activity followed by a gradual decrease was demonstrated with both granulocyte suspension and platelet concentrate. Significant differences were obtained between the materials with a maximum response of Dacron grafts with collagen impregnation for both granulocyte and platelet response. The materials had different surface morphologies regarding cell adhesion after incubation as demonstrated with scanning electron microscopy with more pronounced adhesion on the collagen-impregnated grafts. The results suggest that microcalorimetry may be useful for the evaluation of cellular reactions on different biomaterials. However, further studies have to reveal the specificity of the reactions.

A Process Evaluation of Project Developmental Continuity. Interim Report III, Executive Summary: Preliminary Recommendations for the Study of Child Impact.

ERIC Educational Resources Information Center

Granville, Arthur C.; And Others

This executive summary presents the major findings of Interim Report III, which reports preliminary evaluation of Project Developmental Continuity (PDC). A Head Start demonstration program, PDC is aimed at promoting greater educational and developmental continuity as children make the transition from preschool to school. The report addresses three…

Experiment module concepts study. Volume 5 book 1, appendix A: Shuttle only task

NASA Technical Reports Server (NTRS)

1970-01-01

Results of a preliminary investigation of the effect on the candidate experiment program implementation of experiment module operations in the absence of an orbiting space station and with the availability of the space shuttle orbiter vehicle only are presented. The fundamental hardware elements for shuttle-only operation of the program are: (1) integrated common experiment modules CM-1, CM-3, and CM-4, together with the propulsion slice; (2) support modules capable of supplying on-orbit crew life support, power, data management, and other services normally provided by a space station; (3) dormancy kits to enable normally attached modules to remain in orbit while shuttle returns to earth; and (4) shuttle orbiter. Preliminary cost estimates for 30 day on-orbit and 5 day on-orbit capabilities for a four year implementation period are $4.2 billion and $2.1 billion, respectively.

Preliminary experiments on the reduction of the uranyl ion to uraninite by carbonaceous substances

USGS Publications Warehouse

Breger, Irving A.; Moore, Richard T.

1955-01-01

An aqueous solution of uranyl sulfate containing a suspension of subbituminous coal has been heated at 210 C for three days. Examination of the coal at the end of the experiment showed it to contain 31.8 percent uranium recognizable as uraninite by a sharp, strong X-ray diffraction pattern. A similar experiment with degraded spruce wood also led to the formation of uraninite but in lesser quantity and with broader lines in the X-ray diffraction pattern. The ability of coal or wood to reduce the uranyl ion is a critical factor in the correlation of studies of uraniferous coals containing the uranyl ion with studies of uraninite-bearing coalified wood from the Colorado Plateau. Although these results are based an preliminary experiments, they are extremely important geochemically and warrant the development of the series of controlled studies that are proposed.

A Spherical to Plane Wave Transformation Using a Reflectarray

NASA Technical Reports Server (NTRS)

Zaman, Afroz J.; Lee, Richard Q.

1997-01-01

A reflectarray has generally been used as a replacement for a reflector antenna. Using in this capacity, different configurations (prime focus, offset etc.) and various applications (dual frequency, scanning etc.) have been demonstrated with great success. Another potential application that has not been explored previously is the use of reflectarrays to compensate for phase errors in space power combining applications such as space-fed lens and power combining amplifier. In these applications, it is required to convert a spherical wave to a plane wave with proper phase correction added to each element of the reflectarray. This paper reports an experiment to investigate the feasibility of using a reflectarray as an alternative to a lens in space power combining. The experiment involves transforming a spherical wave from a orthomode horn to a plane wave at the horn aperture. The reflcctarray consists of square patches terminated in open stubs to provide necessary phase compensation. In this paper, preliminary results will be presented and the feasibility of such compensation scheme will be discussed.

Comparing men's and women's experiences of work after cancer: a photovoice study.

PubMed

Morrison, T L; Thomas, R L

2015-10-01

Work is an important quality of life indicator for many cancer survivors. There is, however, a lack of appropriate support to help survivors with work integration. As a result, many survivors are forced to independently navigate their return to work, experiencing unnecessary pitfalls in the process. As a preliminary step toward addressing this current gap in survivorship support, we explored the work integration experiences of 20 cancer survivors, 10 women and 10 men. Photovoice methods were combined with two individual interviews per participant. Participant-produced photographs and interview transcripts were analyzed to identify key themes. Both commonalities and gender-differentiated motivations underlying work integration emerged. Female and male participants both demonstrated and discussed differentiated manners of coping. Men expressed a propensity for productivity and active engagements over talking used predominantly by women. Appreciation of men's proclivity for productivity and activity suggests that a gender-tailored approach to rehabilitation may enhance male survivors' participation and the utility of rehabilitation efforts.

Morphological analysis of the growth stages of in-vivo mouse hair follicles by using optical coherence tomography

NASA Astrophysics Data System (ADS)

Jha, Rakesh Kumar; Kim, Kanghae; Jeon, Mansik; Kim, Jeehyun; Kang, Minyoung; Han, Insook; Kim, Moonkyu

2016-09-01

Swept-source optical coherence tomography (SS-OCT), a bio-photonic imaging modality, was used to demonstrate an initial feasibility experiment for detecting morphological variations of in-vivo mouse hair follicles for the anagen and the telogen growth stages. Two C57BL/6 adult male mice, one undergoing the anagen stage and the other undergoing the telogen stage of the hair follicle growth cycle, were selected for the experiment. The OCT cross-sectional images of mice skin were acquired in-vivo within an interval of 15 days, and the observed morphological changes were analyzed. The micro-structural features of mice skin on the 15th experimental day were further compared with corresponding histological observations. The preliminary result of this study provides clear insights into the structural details of mouse skin, confirming the resemblance of the OCT images with the corresponding histological measurements, and ensures the suitability of SS-OCT for non-invasive analysis of hair follicle conditions.

Enzyme-Cascade Analysis of the Rio Tinto Subsurface Environment: A Biosensor Experiment

NASA Technical Reports Server (NTRS)

McKay, David S.; Lynch, Kennda; Wainwright, Norman; Child, Alice; Williams, Kendra; McKay, David; Amils, Ricardo; Gonzalez, Elena; Stoker, Carol

2004-01-01

The Portable Test System (PTS), designed & developed by Charles Rivers Laboratories, Inc. (Charleston, SC) is a portable instrument that was designed to perform analysis of enzymatic assays related to rapid assessment of microbial contamination (Wainwright, 2003). The enzymatic cascade of Limulus Amebocyte Lysate (LAL) is known to be one of the most sensitive techniques available for microbial detection, enabling the PTS to be evaluated as a potential life detection instrument for in situ Astrobiology missions. In the summer of 2003 the system was tested as a part of the Mars Astrobiology Research and Technology Experiment (MARTE) ground truth science campaign in the Rio Tinto Analogue environment near Nerva, Spain. The preliminary results show that the PTS analysis correlates well with the contamination control tests and the more traditional lab-based biological assays performed during the MARTE field mission. Further work will be conducted on this research during a second field campaign in 2004 and a technology demonstration of a prototype instrument that includes autonomous sample preparation will occur in 2005.

Molecular performance of commercial MTG variety oil palm based on RAPD markers

NASA Astrophysics Data System (ADS)

Putri, L. A. P.; Setyo, I. E.; Basyuni, M.; Bayu, E. S.; Setiado, H.; Reynaldi, N. F.; Laia, H.; Puteri, S. A. K.; Arifiyanto, D.; Syahputra, I.

2018-02-01

The oil palm, an economically important tree in Indonesia, has been one of the world’s major sources of edible oil and a significant precursor of biodiesel fuel. This research is conducted by taking individual tree sample of commercial MTG variety germplasm oil palm one years old. The purpose of this research is to analyse molecular performance of some oil palm MTG variety based on RAPD markers. In this experiment, the DNA profile diversity was assessed using markers of oil palm’s random RAPD markers (OPD-20, SB-19, OPM-01 and OPO-11). A total of 15 trees commercial MTG oil palm variety were used for analysis. The results of the experiment indicated out of 4 RAPD markers (OPD-20, SB-19, OPM-01 and OPO-11) showed polymorphic of PCR product. These preliminary results demonstrated RAPD marker can be used to evaluate genetic relatedness among trees of commercial MTG variety oil palm and detecting either genetic variants or mislabelled.

Water-Soluble Spinel Ferrites by a Modified Polyol Process as Contrast Agents in MRI

NASA Astrophysics Data System (ADS)

Basina, Georgia; Tzitzios, Vasilis; Niarchos, Dimitris; Li, Wanfeng; Khurshid, Hafsa; Mao, Hui; Hadjipanayis, Costas; Hadjipanayis, George

2010-12-01

Magnetic nanoparticles have recently been very attractive for biomedical applications. In this study, we have synthesized ferrite nanoparticles for application as contrast agents in MRI experiments. Fe3O4 and MnFe2O4 spinel ferrites with a mean size of 11-12 nm, were prepared by a modified polyol route in commercially available polyethylene glycol with molecular weight 600 (PEG-600). The reaction takes place in the presence of water soluble and non-toxic tri-block copolymer known as Pluronic® F-127 (PEO100-PPO65-PEO100). The nanoparticles have saturation magnetization values of 52 and 68 emu/g for MnFe2O4 and Fe3O4, respectively. Both the Fe3O4, and MnFe2O4 nanoparticles make stable solutions in water known as ferrofluids. Preliminary data demonstrated the capability of these nanoparticles to induce imaging contrast in T2 weighted MRI experiments, making these materials suitable for biomedical applications such as medical MRI.

Discussion on the solar concentrating thermoelectric generation using micro-channel heat pipe array

NASA Astrophysics Data System (ADS)

Li, Guiqiang; Feng, Wei; Jin, Yi; Chen, Xiao; Ji, Jie

2017-11-01

Heat pipe is a high efficient tool in solar energy applications. In this paper, a novel solar concentrating thermoelectric generation using micro-channel heat pipe array (STEG-MCHP) was presented. The flat-plate micro-channel heat pipe array not only has a higher heat transfer performance than the common heat pipe, but also can be placed on the surface of TEG closely, which can further reduce the thermal resistance between the heat pipe and the TEG. A preliminary comparison experiment was also conducted to indicate the advantages of the STEG-MCHP. The optimization based on the model verified by the experiment was demonstrated, and the concentration ratio and selective absorbing coating area were also discussed. In addition, the cost analysis was also performed to compare between the STEG-MCHP and the common solar concentrating TEGs in series. The outcome showed that the solar concentrating thermoelectric generation using micro-channel heat pipe array has the higher electrical efficiency and lower cost, which may provide a suitable way for solar TEG applications.

Schlieren, Phase-Contrast, and Spectroscopy Diagnostics for the LBNL HIF Plasma Channel Experiment

NASA Astrophysics Data System (ADS)

Ponce, D. M.; Niemann, C.; Fessenden, T. J.; Leemans, W.; Vandersloot, K.; Dahlbacka, G.; Yu, S. S.; Sharp, W. M.; Tauschwitz, A.

1999-11-01

The LBNL Plasma Channel experiment has demonstrated stable 42-cm Z-pinch discharge plasma channels with peak currents in excess of 50 kA for a 7 torr nitrogen, 30 kV discharge. These channels offer the possibility of transporting heavy-ion beams for inertial fusion. We postulate that the stability of these channels resides in the existance of a neutral-gas density depresion created by a pre-pulse discharge before the main capacitor bank discharge is created. Here, we present the results and experimental diagnostics setup used for the study of the pre-pulse and main bank channels. Observation of both the plasma and neutral gas dynamics is achieved. Schlieren, Zernike's phase-contrast, and spectroscopic techniques are used. Preliminary Schlieren results show a gas shockwave moving radially at a rate of ≈ 10^6 mm/sec as a result of the fast and localized deposited energy during the evolution of the pre-pulse channel. This data will be used to validate simulation codes (BUCKY and CYCLOPS).

Fiber Bragg grating sensors for real-time monitoring of evacuation process

NASA Astrophysics Data System (ADS)

Guru Prasad, A. S.; Hegde, Gopalkrishna M.; Asokan, S.

2010-03-01

Fiber bragg grating (FBG) sensors have been widely used for number of sensing applications like temperature, pressure, acousto-ultrasonic, static and dynamic strain, refractive index change measurements and so on. Present work demonstrates the use of FBG sensors in in-situ measurement of vacuum process with simultaneous leak detection capability. Experiments were conducted in a bell jar vacuum chamber facilitated with conventional Pirani gauge for vacuum measurement. Three different experiments have been conducted to validate the performance of FBG sensor in monitoring vacuum creating process and air bleeding. The preliminary results of FBG sensors in vacuum monitoring have been compared with that of commercial Pirani gauge sensor. This novel technique offers a simple alternative to conventional method for real time monitoring of evacuation process. Proposed FBG based vacuum sensor has potential applications in vacuum systems involving hazardous environment such as chemical and gas plants, automobile industries, aeronautical establishments and leak monitoring in process industries, where the electrical or MEMS based sensors are prone to explosion and corrosion.

High-efficiency ytterbium-free erbium-doped all-glass double cladding silicate glass fiber for resonantly-pumped fiber lasers.

PubMed

Qiang, Zexuan; Geng, Jihong; Luo, Tao; Zhang, Jun; Jiang, Shibin

2014-02-01

A highly efficient ytterbium-free erbium-doped silicate glass fiber has been developed for high-power fiber laser applications at an eye-safe wavelength near 1.55 μm. Our preliminary experiments show that high laser efficiency can be obtained from a relatively short length of the gain fiber when resonantly pumped at 1535 nm in both core- and cladding-pumping configurations. With a core-pumping configuration as high as 75%, optical-to-optical efficiency and 4 W output power were obtained at 1560 nm from a 1 m long gain fiber. When using a cladding-pumping configuration, approximately 13 W output power with 67.7% slope efficiency was demonstrated from a piece of 2 m long fiber. The lengths of silicate-based gain fiber are much shorter than their silica-based counterparts used in other experiments, which is significantly important for high-power narrow-band and/or pulsed laser applications.

Whirl measurements on leakage flows in turbomachine models

NASA Technical Reports Server (NTRS)

Addlesee, A. J.; Altiparmak, D.; Pan, S.

1994-01-01

The beneficial effects claimed for whirl control devices demonstrate that the dynamic behavior of rotors is influenced by the fluid whirl in shaft and balance drum seals. The present paper reports results from two series of experiments, the first on the factors affecting the whirl at the seal inlet, and the second on the variation of whirl velocity along the seal. In both cases the LDA measurement technique required the clearance between the fixed and rotating parts of the models to be substantially greater than occurs in real machines, but the results are indicative nevertheless. Experimental and theoretical results are given for the radial distribution of whirl velocity in the gap between impeller shroud and pump casing. Results of tests with modified stator surfaces are also shown. This work leads naturally into the second series of experiments where some preliminary measurements of velocity distribution in the clearance between a fixed stator and a rotating shaft are reported for a range of inlet whirl conditions.

Olive oil enriched in lycopene from tomato by-product through a co-milling process.

PubMed

Bendini, Alessandra; Di Lecce, Giuseppe; Valli, Enrico; Barbieri, Sara; Tesini, Federica; Toschi, Tullia Gallina

2015-01-01

The aim of this investigation was to produce an olive oil (OO) naturally enriched with antioxidants, recovering carotenoids, in particular lycopene, using an industrial by-product of tomato seeds and skin. For this purpose, a technological process in a low-scale industrial plant to co-mill olives and tomato by-product in de-frosted or freeze-dried forms was applied and studied with respect to control samples. Preliminary results obtained from two different experiments were carried out by 40 kg of cultivar Correggiolo olives and 60 kg of olive blends from different cultivars. In both the experiments, the co-milling showed significant enrichment in carotenoids, especially in lycopene (mean values of 5.4 and 7.2 mg/kg oil from defrosted and freeze-dried by-products, respectively). The experimental results demonstrated the possibility to obtain a new functional food naturally enriched in antioxidant compounds, which might be marketed as "OO dressing enriched in lycopene" or "condiment produced using olives and tomato by-product".

Sphingoid esters from the molecular distillation of squid oil: A preliminary bioactivity determination.

PubMed

Saliu, Francesco; Longhin, Eleonora; Salanti, Anika; Degano, Ilaria; Della Pergola, Roberto

2016-06-15

A mixture of sphingoid esters was isolated (1.4% w/w) from the molecular distillation of crude squid visceral oil. A preliminary investigation on the bioactivity profile and toxic potential of this residue was carried out by in vitro experiments. No cytotoxicity and a moderate lipase inhibition activity were highlighted. Copyright © 2016 Elsevier Ltd. All rights reserved.

Source personality and persuasiveness: big five predispositions to being persuasive and the role of message involvement.

PubMed

Oreg, Shaul; Sverdlik, Noga

2014-06-01

In the present studies we incorporate a Person × Situation perspective into the study of the persuasion source. Specifically, we aimed to identify the personality characteristics of the persuasive individual and test the moderating role of target and source involvement. In three studies we found support for hypothesized relationships between source persuasiveness and Extraversion, Neuroticism, and Openness to Experience, and evidence for a moderating effect of involvement. In a preliminary study (N = 66, M(age)  = 22.7, 64% female), we demonstrated expected differences in the personality ratings assigned to a hypothetical persuasive versus nonpersuasive individual. In Study 1 (N = 95, M(age)  = 24.1, 62% female), through sets of two-person debates, we showed that source Extraversion and Openness to Experience were positively, and Neuroticism negatively, associated with source persuasiveness. In Study 2 (N = 148, M(age)  = 24.3, 61% female), we manipulated the level of involvement and mostly replicated the results from Study 1, but, corresponding with our predictions, only when involvement was low. Our findings demonstrate the relevance of an interactionist approach to the study of persuasion, highlighting the role of personality in the study of the persuasion source. © 2013 Wiley Periodicals, Inc.

Imaging through ground-level turbulence by Fourier telescopy: Simulations and preliminary experiments

NASA Astrophysics Data System (ADS)

Randunu Pathirannehelage, Nishantha

Fourier telescopy imaging is a recently-developed imaging method that relies on active structured-light illumination of the object. Reflected/scattered light is measured by a large "light bucket" detector; processing of the detected signal yields the magnitude and phase of spatial frequency components of the object reflectance or transmittance function. An inverse Fourier transform results in the image. In 2012 a novel method, known as time-average Fourier telescopy (TAFT), was introduced by William T. Rhodes as a means for diffraction-limited imaging through ground-level atmospheric turbulence. This method, which can be applied to long horizontal-path terrestrial imaging, addresses a need that is not solved by the adaptive optics methods being used in astronomical imaging. Field-experiment verification of the TAFT concept requires instrumentation that is not available at Florida Atlantic University. The objective of this doctoral research program is thus to demonstrate, in the absence of full-scale experimentation, the feasibility of time-average Fourier telescopy through (a) the design, construction, and testing of small-scale laboratory instrumentation capable of exploring basic Fourier telescopy data-gathering operations, and (b) the development of MATLAB-based software capable of demonstrating the effect of kilometer-scale passage of laser beams through ground-level turbulence in a numerical simulation of TAFT.

Implementation of fast macromolecular proton fraction mapping on 1.5 and 3 Tesla clinical MRI scanners: preliminary experience

NASA Astrophysics Data System (ADS)

Yarnykh, V.; Korostyshevskaya, A.

2017-08-01

Macromolecular proton fraction (MPF) is a biophysical parameter describing the amount of macromolecular protons involved into magnetization exchange with water protons in tissues. MPF represents a significant interest as a magnetic resonance imaging (MRI) biomarker of myelin for clinical applications. A recent fast MPF mapping method enabled clinical translation of MPF measurements due to time-efficient acquisition based on the single-point constrained fit algorithm. However, previous MPF mapping applications utilized only 3 Tesla MRI scanners and modified pulse sequences, which are not commonly available. This study aimed to test the feasibility of MPF mapping implementation on a 1.5 Tesla clinical scanner using standard manufacturer’s sequences and compare the performance of this method between 1.5 and 3 Tesla scanners. MPF mapping was implemented on 1.5 and 3 Tesla MRI units of one manufacturer with either optimized custom-written or standard product pulse sequences. Whole-brain three-dimensional MPF maps obtained from a single volunteer were compared between field strengths and implementation options. MPF maps demonstrated similar quality at both field strengths. MPF values in segmented brain tissues and specific anatomic regions appeared in close agreement. This experiment demonstrates the feasibility of fast MPF mapping using standard sequences on 1.5 T and 3 T clinical scanners.

Specific considerations with the automatic implantable atrial defibrillator.

PubMed

Jung, W; Wolpert, C; Esmailzadeh, B; Spehl, S; Herwig, S; Schumacher, B; Lewalter, T; Omran, H; Kirchhoff, P G; Lüderitz, B

1998-08-01

Internal atrial defibrillation has been evaluated as an alternative approach to the external technique for more than two decades. Previous studies in animals and humans have shown that internal atrial defibrillation is feasible with relatively low energies. The promising results achieved with internal atrial defibrillation have facilitated the development of an implantable atrial defibrillator (IAD). For any new therapy, it is imperative to demonstrate safety, efficacy, tolerability with improvement in quality of life, and cost-effectiveness compared with therapeutic options already available. Maintenance of sinus rhythm or prolonged duration in arrhythmia-free intervals should be demonstrated clearly with an IAD. Initial clinical experience with the Metrix system indicates stable atrial defibrillation thresholds, appropriate R wave synchronization markers, no shock-induced ventricular proarrhythmia, and excellent detection of atrial fibrillation (AF) with a specificity of 100%. Ventricular proarrhythmia has not been reported for correctly R wave synchronized low-energy shocks when closely coupled to RR intervals, and long-short cycles are avoided. Preliminary experience with the Metrix system suggests that the IAD may offer a therapeutic alternative for a subgroup of patients with drug-refractory, symptomatic, long-lasting, and infrequent episodes of AF. Further efforts must be undertaken to reduce the patient discomfort associated with internal atrial defibrillation in an attempt to make this new therapy acceptable to a larger patient population with AF.

Safety Performance of Airborne Separation: Preliminary Baseline Testing

NASA Technical Reports Server (NTRS)

Consiglio, Maria C.; Hoadley, Sherwood T.; Wing, David J.; Baxley, Brian T.

2007-01-01

The Safety Performance of Airborne Separation (SPAS) study is a suite of Monte Carlo simulation experiments designed to analyze and quantify safety behavior of airborne separation. This paper presents results of preliminary baseline testing. The preliminary baseline scenario is designed to be very challenging, consisting of randomized routes in generic high-density airspace in which all aircraft are constrained to the same flight level. Sustained traffic density is varied from approximately 3 to 15 aircraft per 10,000 square miles, approximating up to about 5 times today s traffic density in a typical sector. Research at high traffic densities and at multiple flight levels are planned within the next two years. Basic safety metrics for aircraft separation are collected and analyzed. During the progression of experiments, various errors, uncertainties, delays, and other variables potentially impacting system safety will be incrementally introduced to analyze the effect on safety of the individual factors as well as their interaction and collective effect. In this paper we report the results of the first experiment that addresses the preliminary baseline condition tested over a range of traffic densities. Early results at five times the typical traffic density in today s NAS indicate that, under the assumptions of this study, airborne separation can be safely performed. In addition, we report on initial observations from an exploration of four additional factors tested at a single traffic density: broadcast surveillance signal interference, extent of intent sharing, pilot delay, and wind prediction error.

Monitoring the Microgravity Environment Quality On-board the International Space Station Using Soft Computing Techniques. Part 2; Preliminary System Performance Results

NASA Technical Reports Server (NTRS)

Jules, Kenol; Lin, Paul P.; Weiss, Daniel S.

2002-01-01

This paper presents the preliminary performance results of the artificial intelligence monitoring system in full operational mode using near real time acceleration data downlinked from the International Space Station. Preliminary microgravity environment characterization analysis result for the International Space Station (Increment-2), using the monitoring system is presented. Also, comparison between the system predicted performance based on ground test data for the US laboratory "Destiny" module and actual on-orbit performance, using measured acceleration data from the U.S. laboratory module of the International Space Station is presented. Finally, preliminary on-orbit disturbance magnitude levels are presented for the Experiment of Physics of Colloids in Space, which are compared with on ground test data. The ground test data for the Experiment of Physics of Colloids in Space were acquired from the Microgravity Emission Laboratory, located at the NASA Glenn Research Center, Cleveland, Ohio. The artificial intelligence was developed by the NASA Glenn Principal Investigator Microgravity Services Project to help the principal investigator teams identify the primary vibratory disturbance sources that are active, at any moment of time, on-board the International Space Station, which might impact the microgravity environment their experiments are exposed to. From the Principal Investigator Microgravity Services' web site, the principal investigator teams can monitor via a dynamic graphical display, implemented in Java, in near real time, which event(s) is/are on, such as crew activities, pumps, fans, centrifuges, compressor, crew exercise, structural modes, etc., and decide whether or not to run their experiments, whenever that is an option, based on the acceleration magnitude and frequency sensitivity associated with that experiment. This monitoring system detects primarily the vibratory disturbance sources. The system has built-in capability to detect both known and unknown vibratory disturbance sources. Several soft computing techniques such as Kohonen's Self-Organizing Feature Map, Learning Vector Quantization, Back-Propagation Neural Networks, and Fuzzy Logic were used to design the system.

A Centralized Display for Mission Monitoring

NASA Technical Reports Server (NTRS)

Trujillo, Anna C.

2004-01-01

Humans traditionally experience a vigilance decrement over extended periods of time on reliable systems. One possible solution to aiding operators in monitoring is to use polar-star displays that will show deviations from normal in a more salient manner. The primary objectives of this experiment were to determine if polar-star displays aid in monitoring and preliminary diagnosis of the aircraft state. This experiment indicated that the polar-star display does indeed aid operators in detecting and diagnosing system events. Subjects were able to notice system events earlier and they subjectively reported the polar-star display helped them in monitoring, noticing an event, and diagnosing an event. Therefore, these results indicate that the polar-star display used for monitoring and preliminary diagnosis improves performance in these areas for system related events.

Rapid and reliable healing of critical size bone defects with genetically modified sheep muscle.

PubMed

Liu, F; Ferreira, E; Porter, R M; Glatt, V; Schinhan, M; Shen, Z; Randolph, M A; Kirker-Head, C A; Wehling, C; Vrahas, M S; Evans, C H; Wells, J W

2015-09-21

Large segmental defects in bone fail to heal and remain a clinical problem. Muscle is highly osteogenic, and preliminary data suggest that autologous muscle tissue expressing bone morphogenetic protein-2 (BMP-2) efficiently heals critical size defects in rats. Translation into possible human clinical trials requires, inter alia, demonstration of efficacy in a large animal, such as the sheep. Scale-up is fraught with numerous biological, anatomical, mechanical and structural variables, which cannot be addressed systematically because of cost and other practical issues. For this reason, we developed a translational model enabling us to isolate the biological question of whether sheep muscle, transduced with adenovirus expressing BMP-2, could heal critical size defects in vivo. Initial experiments in athymic rats noted strong healing in only about one-third of animals because of unexpected immune responses to sheep antigens. For this reason, subsequent experiments were performed with Fischer rats under transient immunosuppression. Such experiments confirmed remarkably rapid and reliable healing of the defects in all rats, with bridging by 2 weeks and remodelling as early as 3-4 weeks, despite BMP-2 production only in nanogram quantities and persisting for only 1-3 weeks. By 8 weeks the healed defects contained well-organised new bone with advanced neo-cortication and abundant marrow. Bone mineral content and mechanical strength were close to normal values. These data demonstrate the utility of this model when adapting this technology for bone healing in sheep, as a prelude to human clinical trials.

Methods of Combinatorial Optimization to Reveal Factors Affecting Gene Length

PubMed Central

Bolshoy, Alexander; Tatarinova, Tatiana

2012-01-01

In this paper we present a novel method for genome ranking according to gene lengths. The main outcomes described in this paper are the following: the formulation of the genome ranking problem, presentation of relevant approaches to solve it, and the demonstration of preliminary results from prokaryotic genomes ordering. Using a subset of prokaryotic genomes, we attempted to uncover factors affecting gene length. We have demonstrated that hyperthermophilic species have shorter genes as compared with mesophilic organisms, which probably means that environmental factors affect gene length. Moreover, these preliminary results show that environmental factors group together in ranking evolutionary distant species. PMID:23300345

Critical point wetting drop tower experiment

NASA Technical Reports Server (NTRS)

Kaukler, W. F.; Tcherneshoff, L. M.; Straits, S. R.

1984-01-01

Preliminary results for the Critical Point Wetting CPW Drop Tower Experiment are produced with immiscible systems. Much of the observed phenomena conformed to the anticipated behavior. More drops will be needed to test the CPW theory with these immiscible systems.

Experimental design for research on shock-turbulence interaction

NASA Technical Reports Server (NTRS)

Radcliffe, S. W.

1969-01-01

Report investigates the production of acoustic waves in the interaction of a supersonic shock and a turbulence environment. The five stages of the investigation are apparatus design, development of instrumentation, preliminary experiment, turbulence generator selection, and main experiments.

MISSE-7 MESA Miniaturized Electrostatic Analyzer - Ion Spectra Analysis Preliminary Results

NASA Astrophysics Data System (ADS)

Enloe, C. L.; Balthazor, R. L.; McHarg, M. G.; Clark, A. L.; Waite, D.; Wallerstein, A. J.; Wilson, K. A.

2011-12-01

The 7th Materials on the International Space Station Experiment (MISSE-7) was launched in November 2009 and retrieved on STS-134 in April 2011. One of the onboard experiments, the Miniaturized Electrostatic Analyzer (MESA), is a small low-cost low-size/weight/power ion and electron spectrometer that was pointed into ram during the majority of the time onboard. Over 800 Mb of data has been obtained by taking spectra every three minutes on-orbit. The data has been analyzed with a novel "parameterizing the parameters" method suitable for on-orbit data analysis using low-cost microcontrollers. Preliminary results are shown.

Onyx, a New Liquid Embolic Material for Peripheral Interventions: Preliminary Experience in Aneurysm, Pseudoaneurysm, and Pulmonary Arteriovenous Malformation Embolization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vanninen, Ritva L., E-mail: ritva.vanninen@kuh.fi; Manninen, I.

Purpose. To describe our preliminary experience with a new liquid embolization agent, Onyx, in peripheral interventions. Methods and results. We successfully treated two peripheral aneurysms (one in an internal iliac artery, one in a thoracic collateral artery of an aortic coarctation), two peripheral pseudoaneurysms (one in a lumbar artery, one in a renal artery), and one pulmonary arteriovenous malformation. Conclusion. Onyx is a promising alternative embolic material for peripheral interventions. It can be combined with coils in selected cases, and balloon catheters can be effectively used during slow injection of embolic material to control flow and protect the aneurysm neck.

A new oral contraceptive regimen for endometriosis management: preliminary experience with 24/4-day drospirenone/ethinylestradiol 3 mg/20 mcg.

PubMed

Mabrouk, Mohamed; Solfrini, Serena; Frascà, Clarissa; Del Forno, Simona; Montanari, Giulia; Ferrini, Giulia; Paradisi, Roberto; Seracchioli, Renato

2012-06-01

We report our preliminary experience with the use of a low-dose oral contraceptive containing Drospirenone/Ethinylestradiol 3 mg/20 mcg, both in cyclic and continuous regimen for endometriosis management. A total of 93 women were retrospectively included: 52 were treated by medical therapy (exclusive combined oral contraceptives (COC)-users), while 41 were submitted to surgery followed by postoperative therapy (postoperative COC-users). A clinical examination was performed at baseline and at 6-months follow-up. Presence and intensity of endometriosis-related symptoms were assessed by a visual analogue scale. Presence and dimension of endometriotic lesions were evaluated by transvaginal ultrasonography. Adverse effects and tolerability were analysed. In exclusive COC-users, significant reductions in dysmenorrhoea and dyspareunia scores and in endometrioma mean diameter were observed at follow-up. In postoperative COC-users, anatomical and symptom recurrence rates at follow-up were 4.9% and 17%, respectively. The most frequent adverse effects were spotting and headache. No difference between cyclic and continuous regimen in terms of symptom relief, lesion progression and tolerability was observed. From our preliminary experience, Drospirenone/Ethinylestradiol 3 mg/20 mcg seems to be promising in endometriosis management.

A universal ankle-foot prosthesis emulator for human locomotion experiments.

PubMed

Caputo, Joshua M; Collins, Steven H

2014-03-01

Robotic prostheses have the potential to significantly improve mobility for people with lower-limb amputation. Humans exhibit complex responses to mechanical interactions with these devices, however, and computational models are not yet able to predict such responses meaningfully. Experiments therefore play a critical role in development, but have been limited by the use of product-like prototypes, each requiring years of development and specialized for a narrow range of functions. Here we describe a robotic ankle-foot prosthesis system that enables rapid exploration of a wide range of dynamical behaviors in experiments with human subjects. This emulator comprises powerful off-board motor and control hardware, a flexible Bowden cable tether, and a lightweight instrumented prosthesis, resulting in a combination of low mass worn by the human (0.96 kg) and high mechatronic performance compared to prior platforms. Benchtop tests demonstrated closed-loop torque bandwidth of 17 Hz, peak torque of 175 Nm, and peak power of 1.0 kW. Tests with an anthropomorphic pendulum "leg" demonstrated low interference from the tether, less than 1 Nm about the hip. This combination of low worn mass, high bandwidth, high torque, and unrestricted movement makes the platform exceptionally versatile. To demonstrate suitability for human experiments, we performed preliminary tests in which a subject with unilateral transtibial amputation walked on a treadmill at 1.25 ms-1 while the prosthesis behaved in various ways. These tests revealed low torque tracking error (RMS error of 2.8 Nm) and the capacity to systematically vary work production or absorption across a broad range (from -5 to 21 J per step). These results support the use of robotic emulators during early stage assessment of proposed device functionalities and for scientific study of fundamental aspects of human-robot interaction. The design of simple, alternate end-effectors would enable studies at other joints or with additional degrees of freedom.

Minimally invasive video-assisted parathyroidectomy. Initial experience in a General Surgery Department.

PubMed

Dobrinja, C; Trevisan, G; Liguori, G

2009-02-01

The aim of this study is to analyze our preliminary results from minimally invasive video-assisted parathyroidectomy (MIVAP) and demonstrate the feasibility of MIVAP also in non-referral centers. During a period from June 2005 to January 2008, in the General Surgery Department of University of Trieste, we operated on 39 patients with primary hyperparathyroidism (pHPT). MIVAP by an anterior approach was proposed for 23 (59%) patients with sporadic pHPT and one unequivocally enlarged parathyroid gland on pre-operative ultrasound and 99mTc-SestaMIBI scintigraphy without associated goiter and without previous neck surgery. Intra-operatively, a quick parathyroid assay was used during the last 11 surgical procedures. All patients underwent pre-operative and post-operative investigations of calcemia, phoshoremia and PTH levels and vocal cord function. Age, operative times, pathologic findings, post-operative pain, calcemia, length of hospital stay, cosmetic results, and complications were retrospectively analyzed. MIVAP was successfully accomplished in 22 cases. Conversion to standard cervicotomy was required in one patient (4.34%). Mean operative time was 67 min. Post-operative complications included 1 (4.34%) transient hypocalcemia. No laryngeal nerve palsies, no definitive hypocalcemias, no persistent pHPT and no recurrent pHPT were observed. The cosmetic result was excellent in all cases. Our preliminary results demonstrate that MIVAP for localized single-gland adenoma, after adequate training, seems to be feasible with significant advantages, especially in terms of cosmetic results, post-operative pain, and post-operative recovery even in a General Surgery Department, if performed by a dedicated team, with a sufficient and specific activity volume.

Preliminary study on the responses of three marine algae, Ulva pertusa (Chlorophyta), Gelidium amansii (Rhodophyta) and Sargassum enerve (Phaeophyta), to nitrogen source and its availability

NASA Astrophysics Data System (ADS)

Liu, Dongyan; Amy, Pickering; Sun, Jun

2004-04-01

An experiment was designed to select economically valuable macroalga species with high nutrient uptake rates. Such species cultured on a large scale could be a potential solution to eutrophication. Three macroalgae species, Ulva pertusa (Chlorophyta), Gelidium amansii (Rhodophyta) and Sargassum enerve (Phaeophyta), were chosen for the experiment because of their economic values and availability. Control and four nitrogen concentrations were achieved by adding NH{4/+} and NO{3/-}. The results indicate that the fresh weights of all species increase faster than that of control after 5 d culture. The fresh weight of Ulva pertusa increases fastest among the 3 species. However, different species show different responses to nitrogen source and its availability. They also show the advantage of using NH{4/+} than using NO{3/-}. U. pertusa grows best and shows higher capability of removing nitrogen at 200µmolL-1, but it has lower economical value. G. amansii has higher economical value but lower capability of removing nitrogen at 200 µmolL-1. The capability of nitrogen assimilation of S. enerve is higher than that of G. amansii at 200µmolL -1, but the former’s increase of fresh weight is lower than those of other two species. Then present preliminary study demonstrates that it is possible to use macroalgae as biofilters and further development of this approach could provide biologically valuable information on the source, fate, and transport of N in marine ecosystems. Caution is needed should we extrapolate these findings to natural environments.

Stereotactic body radiotherapy (SBRT): Technological innovation and application in gynecologic oncology.

PubMed

Higginson, Daniel S; Morris, David E; Jones, Ellen L; Clarke-Pearson, Daniel; Varia, Mahesh A

2011-03-01

Stereotactic body radiotherapy (SBRT) is a novel form of noninvasive, highly conformal radiation treatment that delivers a high dose to tumor. The advantage of the technique resides in its ability to provide a high dose to tumor but spare normal tissues to an extent not previously possible. In this paper we will provide an introduction and review of this technology with regard to its use in gynecologic malignancies. Preliminary results from our experience are presented for the purpose of illustrating the range of SBRT applications in gynecologic oncology. A comprehensive literature review was conducted and our experience from the past three years was reviewed. Six case series are published that report results of SBRT for gynecologic malignancies. Sixteen gynecologic patients have been treated with SBRT at our institution. Treatment sites include pelvic and periaortic nodes (9 patients), oligometastatic disease (2), and cervical or endometrial primary tumors when other conventional external radiation or brachytherapy techniques were unsuitable (5). Preliminary follow-up at a median of 11 months (range, 0.3-33 months) demonstrates 79% locoregional control, 43% distant failure, and 50% overall survival. SBRT boosts to macroscopic periaortic node recurrences and other sites seem to provide local control and a possibility of long-term disease-free survival in carefully selected patients. Previously this had been difficult to achieve with conventional radiotherapy because of the proximity of periaortic nodes to small bowel. SBRT also offers a novel approach for minimally invasive treatment in the management of gynecological cancer where current surgical and radiotherapy techniques are unsuitable. Copyright © 2010 Elsevier Inc. All rights reserved.

Stimulus selectivity of drug purchase tasks: A preliminary study evaluating alcohol and cigarette demand.

PubMed

Strickland, Justin C; Stoops, William W

2017-06-01

The use of drug purchase tasks to measure drug demand in human behavioral pharmacology and addiction research has proliferated in recent years. Few studies have systematically evaluated the stimulus selectivity of drug purchase tasks to demonstrate that demand metrics are specific to valuation of or demand for the commodity under study. Stimulus selectivity is broadly defined for this purpose as a condition under which a specific stimulus input or target (e.g., alcohol, cigarettes) is the primary determinant of behavior (e.g., demand). The overall goal of the present study was to evaluate the stimulus selectivity of drug purchase tasks. Participants were sampled from the Amazon.com's crowdsourcing platform Mechanical Turk. Participants completed either alcohol and soda purchase tasks (Experiment 1; N = 139) or cigarette and chocolate purchase tasks (Experiment 2; N = 46), and demand metrics were compared to self-reported use behaviors. Demand metrics for alcohol and soda were closely associated with commodity-similar (e.g., alcohol demand and weekly alcohol use) but not commodity-different (e.g., alcohol demand and weekly soda use) variables. A similar pattern was observed for cigarette and chocolate demand, but selectivity was not as consistent as for alcohol and soda. Collectively, we observed robust selectivity for alcohol and soda purchase tasks and modest selectivity for cigarette and chocolate purchase tasks. These preliminary outcomes suggest that demand metrics adequately reflect the specific commodity under study and support the continued use of purchase tasks in substance use research. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Image guided percutaneous spine procedures using an optical see-through head mounted display: proof of concept and rationale.

PubMed

Deib, Gerard; Johnson, Alex; Unberath, Mathias; Yu, Kevin; Andress, Sebastian; Qian, Long; Osgood, Gregory; Navab, Nassir; Hui, Ferdinand; Gailloud, Philippe

2018-05-30

Optical see-through head mounted displays (OST-HMDs) offer a mixed reality (MixR) experience with unhindered procedural site visualization during procedures using high resolution radiographic imaging. This technical note describes our preliminary experience with percutaneous spine procedures utilizing OST-HMD as an alternative to traditional angiography suite monitors. MixR visualization was achieved using the Microsoft HoloLens system. Various spine procedures (vertebroplasty, kyphoplasty, and percutaneous discectomy) were performed on a lumbar spine phantom with commercially available devices. The HMD created a real time MixR environment by superimposing virtual posteroanterior and lateral views onto the interventionalist's field of view. The procedures were filmed from the operator's perspective. Videos were reviewed to assess whether key anatomic landmarks and materials were reliably visualized. Dosimetry and procedural times were recorded. The operator completed a questionnaire following each procedure, detailing benefits, limitations, and visualization mode preferences. Percutaneous vertebroplasty, kyphoplasty, and discectomy procedures were successfully performed using OST-HMD image guidance on a lumbar spine phantom. Dosimetry and procedural time compared favorably with typical procedural times. Conventional and MixR visualization modes were equally effective in providing image guidance, with key anatomic landmarks and materials reliably visualized. This preliminary study demonstrates the feasibility of utilizing OST-HMDs for image guidance in interventional spine procedures. This novel visualization approach may serve as a valuable adjunct tool during minimally invasive percutaneous spine treatment. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Preliminary assessment of the interaction of introduced biological agents with biofilms in water distribution systems.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sinclair, Michael B.; Caldwell, Sara; Jones, Howland D. T.

2005-12-01

Basic research is needed to better understand the potential risk of dangerous biological agents that are unintentionally or intentionally introduced into a water distribution system. We report on our capabilities to conduct such studies and our preliminary investigations. In 2004, the Biofilms Laboratory was initiated for the purpose of conducting applied research related to biofilms with a focus on application, application testing and system-scale research. Capabilities within the laboratory are the ability to grow biofilms formed from known bacteria or biofilms from drinking water. Biofilms can be grown quickly in drip-flow reactors or under conditions more analogous to drinking-water distributionmore » systems in annular reactors. Biofilms can be assessed through standard microbiological techniques (i .e, aerobic plate counts) or with various visualization techniques including epifluorescent and confocal laser scanning microscopy and confocal fluorescence hyperspectral imaging with multivariate analysis. We have demonstrated the ability to grow reproducible Pseudomonas fluorescens biofilms in the annular reactor with plate counts on the order of 10{sup 5} and 10{sup 6} CFU/cm{sup 2}. Stationary phase growth is typically reached 5 to 10 days after inoculation. We have also conducted a series of pathogen-introduction experiments, where we have observed that both polystyrene microspheres and Bacillus cereus (as a surrogate for B. anthracis) stay incorporated in the biofilms for the duration of our experiments, which lasted as long as 36 days. These results indicated that biofilms may act as a safe harbor for bio-pathogens in drinking water systems, making it difficult to decontaminate the systems.« less

Investigation of decolorization of textile wastewater in an anaerobic/aerobic biological activated carbon system (A/A BAC).

PubMed

Pasukphun, N; Vinitnantharat, S; Gheewala, S

2010-04-01

The aim of this study is to investigate the decolorization in anaerobic/aerobic biological activated carbon (A/A BAC) system. The experiment was divided into 2 stages; stage I is batch test for preliminary study of dye removal equilibrium time. The preliminary experiment (stage I) provided the optimal data for experimental design of A/A BAC system in SBR (stage II). Stage II is A/A BAC system imitated Sequencing Batch Reactor (SBR) which consist of 5 main periods; fill, react, settle, draw and idle. React period include anaerobic phase followed by aerobic phase. The BAC main media; Granular Activated Carbon (GAC), Mixed Cultures (MC) and Biological Activated Carbon (BAC) were used for dye and organic substances removal in three different solutions; Desizing Agent Solution (DAS), dye Solution (DS) and Synthetic Textile Wastewater (STW). Results indicate that GAC adsorption plays role in dye removal followed by BAC and MC activities, respectively. In the presence desizing agent, decolorization by MC was improved because desizing agent acts as co-substrates for microorganisms. It was found that 50% of dye removal efficiency was achieved in Fill period by MC. GC/MS analysis was used to identify dye intermediate from decolorization. Dye intermediate containing amine group was found in the solution and on BAC surfaces. The results demonstrated that combination of MC and BAC in the system promotes decolorization and dye intermediate removal. In order to improve dye removal efficiency in an A/A BAC system, replacement of virgin GAC, sufficient co-substrates supply and the appropriate anaerobic: aerobic period should be considered.

GPS Ocean Reflection Experiment on Spartan 251

NASA Technical Reports Server (NTRS)

Garrison, James L; Russo, Angela; Mickler, Dave; Armatys, Michael; Ferebee, Melvin J.

1999-01-01

It has recently been demonstrated that the GPS signal which has reflected from the ocean surface contains useful geophysical data from which the sea surface wind speed and other parameters can be extracted. This can be used for remote sensing, similar to present day use of radar altimeters or scatterometers, but with significantly smaller instrumentation because of the utilization of the existing GPS broadcast signal for illumination. Several campaigns of aircraft experimentation have been completed demonstrating this technique and reflected GPS data has been reliably collected from 25 km altitude on a balloon. However, there has not yet been a demonstration that the reflected GPS signal can be detected from orbit with sufficient signal to noise ratio (SNR) to make useful remote sensing measurements. A technology demonstration experiment was planned for a Space Shuttle flight in the late 2000 using the Spartan 251 recoverable carrier. This experiment would also have been the first flight validation of the PiVoT GPS receiver developed in house at the Goddard Space Flight Center. The "open-architecture" design of this receiver would allow the software modifications to be made which control code-correlator spacing to map out the shape of the reflected signal waveform, which is the most basic data product generated by this instrumentation. A moderate gain left-hand circularly polarized antenna, constructed from an array of off-the-shelf hemispherical antennas was to be used to give approximately 3 to 6 dB of additional gain. Preliminary SNR predictions have been done indicating that this antenna would offer sufficient gain to record waveform measurements. A system level description of the experiment instrumentation, including the receiver, antenna and data storage and retrieval will be given. The visibility of GPS reflections over the mission duration of several hours will be studied, including the effects of the limited beamwidth of the antenna. Spartan 251 has now been postponed with the earliest opportunity in the year 2002. The results of this study however, have been 2 used to further the define the requirements and expected performance of reflected GPS receivers in orbit. Several other space flight opportunities are being considered based upon this new information.

Bullying Experiences among Children and Youth with Autism Spectrum Disorders

ERIC Educational Resources Information Center

Cappadocia, M. Catherine; Weiss, Jonathan A.; Pepler, Debra

2012-01-01

Few studies have investigated bullying experiences among children diagnosed with autism spectrum disorders (ASD); however, preliminary research suggests that children with ASD are at greater risk for being bullied than typically developing peers. The aim of the current study was to build an understanding of bullying experiences among children with…

The Impact of Study Abroad Experiences on Vocational Identity among College Students

ERIC Educational Resources Information Center

Kronholz, Julia F.; Osborn, Debra S.

2016-01-01

The purpose of this study was to determine preliminary findings regarding the effect of a study abroad experience on vocational identity and career decision-making as defined by Cognitive Information Processing (CIP) theory (Sampson et al., 2004). The results revealed that a study abroad experience significantly impacts college students'…

Experience from a multicentre stroke register: a preliminary report

PubMed Central

Hatano, S.

1976-01-01

In collaboration with 15 centres in 10 countries of Africa, Asia, and Europe, WHO started a pilot study of a community-based stroke register, with standardized methods. Preliminary data were obtained on 6395 new cases of stroke in defined study communities, from May 1971 to September 1974. Information on incidence rates, clinical profiles, diagnosis, management, and course and prognosis for these patients is given. PMID:1088404

Pathways to the Future: A Longitudinal Study of Young Americans. Preliminary Report: Youth and the Labor Market--1979.

ERIC Educational Resources Information Center

Borus, Michael E.; And Others

This monograph presents preliminary cross-tabulation analyses of the 1979 National Longitudinal Survey of Youth Labor Market Experience of 12,693 youth of ages 14-21 who will be interviewed annually for at least five years. (Hispanic; non-Hispanic black; and non-Hispanic, non-black, poor youth were oversampled.) Each of the twenty-four topics…

A Preliminary Investigation of the Effects of Giving Testimony and Learning Yogic Breathing Techniques on Battered Women's Feelings of Depression

ERIC Educational Resources Information Center

Franzblau, Susan H.; Echevarria, Sonia; Smith, Michelle; Van Cantfort, Thomas E.

2008-01-01

Researchers have shown that mood and sense of control over one's life are significantly affected by testimony and other forms of disclosure and that learning to control breathing has positive effects on mood and anxiety. This preliminary experiment tests whether African American and European American abused women who give testimony about their…

Chemical Analysis of the Moon at the Surveyor VI Landing Site: Preliminary Results.

PubMed

Turkevich, A L; Patterson, J H; Franzgrote, E J

1968-06-07

The alpha-scattering experiment aboard soft-landing Surveyor VI has provided a chemical analysis of the surface of the moon in Sinus Medii. The preliminary results indicate that, within experimental errors, the composition is the same as that found by Surveyor V in Mare Tranquillitatis. This finding suggests that large portions of the lunar maria resemble basalt in composition.

Visual Knowledge in Tactical Planning: Preliminary Knowledge Acquisition Phase 1 Technical Report

DTIC Science & Technology

1990-04-05

MANAGEMENT INFORMATION , COMMUNICATIONS, AND COMPUTER SCIENCES Visual Knowledge in Tactical Planning: Preliminary Knowledge Acquisition Phase I Technical...perceived provides information in multiple modalities and, in fact, we may rely on a non-verbal mode for much of our understanding of the situation...some tasks, almost all the pertinent information is provided via diagrams, maps, znd other illustrations. Visual Knowledge Visual experience forms a

SARDA HITL Preliminary Human Factors Measures and Analyses

NASA Technical Reports Server (NTRS)

Hyashi, Miwa; Dulchinos, Victoria

2012-01-01

Human factors data collected during the SARDA HITL Simulation Experiment include a variety of subjective measures, including the NASA TLX, questionnaire questions regarding situational awareness, advisory usefulness, UI usability, and controller trust. Preliminary analysis of the TLX data indicate that workload may not be adversely affected by use of the advisories, additionally, the controller's subjective ratings of the advisories may suggest acceptance of the tool.

Preliminary data for the 20 May 1974, simultaneous evaluation of remote sensors experiment. [water pollution monitoring

NASA Technical Reports Server (NTRS)

Johnson, R. W.; Batten, C. E.; Bowker, D. E.; Bressette, W. E.; Grew, G. W.

1975-01-01

Several remote sensors were simultaneously used to collect data over the tidal James River from Hopewell to Norfolk, Virginia. Sensors evaluated included the Multichannel-Ocean Color Sensor, multispectral scanners, and multispectral photography. Ground truth measurements and remotely sensed data are given. Preliminary analysis indicates that suspended sediment and concentrated industrial effluent are observable from all sensors.

Measuring the impact and distress of health problems from the individual's perspective: development of the Perceived Impact of Problem Profile (PIPP)

PubMed Central

Pallant, Julie F; Misajon, RoseAnne; Bennett, Elizabeth; Manderson, Lenore

2006-01-01

Background The aim of this study was to develop and conduct preliminary validation of the Perceived Impact of Problem Profile (PIPP). Based on the biopsychosocial model of health and functioning, the PIPP was intended as a generic research and clinical measurement tool to assess the impact and distress of health conditions from the individuals' perspective. The ICF classification system was used to guide the structure of the PIPP with subscales included to assess impact on self-care, mobility, participation, relationships and psychological well-being. While the ICF focuses on the classification of objective health and health related status, the PIPP broadens this focus to address the individuals' subjective experience of their health condition. Methods An item pool of 23 items assessing both impact and distress on five key domains was generated. These were administered to 169 adults with mobility impairment. Rasch analysis using RUMM2020 was conducted to assess the psychometric properties of each set of items. Preliminary construct validation of the PIPP was performed using the EQ5D. Results For both the Impact and Distress scales of the PIPP, the five subscales (Self-care, Mobility, Participation, Relationships, and Psychological Well-being) showed adequate psychometric properties, demonstrating fit to the Rasch model. All subscales showed adequate person separation reliability and no evidence of differential item functioning for sex, age, educational level or rural vs urban residence. Preliminary validity testing using the EQ5D items provided support for the subscales. Conclusion This preliminary study, using a sample of adults with mobility impairment, provides support for the psychometric properties of the PIPP as a potential clinical and research measurement tool. The PIPP provides a brief, but comprehensive means to assess the key ICF components, focusing on the individuals' perspective of the impact and distress caused by their health condition. Further validation of its use across different health conditions and varying cultural settings is required. PMID:16808842

Online Activities for Enhancing Sex Education Curricula: Preliminary Evidence on the Effectiveness of the Abstinence and Contraception Education Storehouse

PubMed Central

Raghupathy, Shobana; Klein, Charles; Card, Josefina

2013-01-01

The purpose of this research was to conduct a preliminary evaluation of the Abstinence and Contraception Education Storehouse (ACES), a digital, classroom-based resource designed to supplement existing sex education curricula with highly interactive materials such as video clips, multimedia polls and quizzes, and audiovisual demonstrations. 335 students ages 14–19 were randomly assigned to an ACES–based (treatment) or a standard (control) sex education curriculum. Data were collected at the onset of the intervention and 3-months after the completion of the intervention. Preliminary results were highly encouraging, with ACES participants who were sexually initiated at baseline reporting at the 3-month follow-up significant reductions in the number of times they had sex in the past four weeks. Both sexually initiated and non-sexually initiated youth who experienced the ACES curriculum also demonstrated greater intent to abstain from the sex during the follow-up period than those in the control group. PMID:24078799

Multidisciplinary optimization of controlled space structures with global sensitivity equations

NASA Technical Reports Server (NTRS)

Padula, Sharon L.; James, Benjamin B.; Graves, Philip C.; Woodard, Stanley E.

1991-01-01

A new method for the preliminary design of controlled space structures is presented. The method coordinates standard finite element structural analysis, multivariable controls, and nonlinear programming codes and allows simultaneous optimization of the structures and control systems of a spacecraft. Global sensitivity equations are a key feature of this method. The preliminary design of a generic geostationary platform is used to demonstrate the multidisciplinary optimization method. Fifteen design variables are used to optimize truss member sizes and feedback gain values. The goal is to reduce the total mass of the structure and the vibration control system while satisfying constraints on vibration decay rate. Incorporating the nonnegligible mass of actuators causes an essential coupling between structural design variables and control design variables. The solution of the demonstration problem is an important step toward a comprehensive preliminary design capability for structures and control systems. Use of global sensitivity equations helps solve optimization problems that have a large number of design variables and a high degree of coupling between disciplines.

King County Metro Battery Electric Bus Demonstration: Preliminary Project Results

DOE Office of Scientific and Technical Information (OSTI.GOV)

The U.S. Federal Transit Administration (FTA) funds a variety of research projects that support the commercialization of zero-emission bus technology. To evaluate projects funded through these programs, FTA has enlisted the help of the National Renewable Energy Laboratory (NREL) to conduct third-party evaluations of the technologies deployed under the FTA programs. NREL works with the selected agencies to evaluate the performance of the zero-emission buses compared to baseline conventional buses in similar service. The evaluation effort will advance the knowledge base of zero-emission technologies in transit bus applications and provide 'lessons learned' to aid other fleets in incrementally introducing nextmore » generation zero-emission buses into their operations. This report provides preliminary performance evaluation results from a demonstration of three zero-emission battery electric buses at King County Metro in King County, Washington. NREL developed this preliminary results report to quickly disseminate evaluation results to stakeholders. Detailed evaluation results will be published in future reports.« less

Cascade Optimization Strategy with Neural Network and Regression Approximations Demonstrated on a Preliminary Aircraft Engine Design

NASA Technical Reports Server (NTRS)

Hopkins, Dale A.; Patnaik, Surya N.

2000-01-01

A preliminary aircraft engine design methodology is being developed that utilizes a cascade optimization strategy together with neural network and regression approximation methods. The cascade strategy employs different optimization algorithms in a specified sequence. The neural network and regression methods are used to approximate solutions obtained from the NASA Engine Performance Program (NEPP), which implements engine thermodynamic cycle and performance analysis models. The new methodology is proving to be more robust and computationally efficient than the conventional optimization approach of using a single optimization algorithm with direct reanalysis. The methodology has been demonstrated on a preliminary design problem for a novel subsonic turbofan engine concept that incorporates a wave rotor as a cycle-topping device. Computations of maximum thrust were obtained for a specific design point in the engine mission profile. The results (depicted in the figure) show a significant improvement in the maximum thrust obtained using the new methodology in comparison to benchmark solutions obtained using NEPP in a manual design mode.

Online Activities for Enhancing Sex Education Curricula: Preliminary Evidence on the Effectiveness of the Abstinence and Contraception Education Storehouse.

PubMed

Raghupathy, Shobana; Klein, Charles; Card, Josefina

2013-01-01

The purpose of this research was to conduct a preliminary evaluation of the Abstinence and Contraception Education Storehouse (ACES), a digital, classroom-based resource designed to supplement existing sex education curricula with highly interactive materials such as video clips, multimedia polls and quizzes, and audiovisual demonstrations. 335 students ages 14-19 were randomly assigned to an ACES-based (treatment) or a standard (control) sex education curriculum. Data were collected at the onset of the intervention and 3-months after the completion of the intervention. Preliminary results were highly encouraging, with ACES participants who were sexually initiated at baseline reporting at the 3-month follow-up significant reductions in the number of times they had sex in the past four weeks. Both sexually initiated and non-sexually initiated youth who experienced the ACES curriculum also demonstrated greater intent to abstain from the sex during the follow-up period than those in the control group.

The FRD and transmission of the 270-m GRACES optical fiber link and a high numerical aperture fiber for astronomy

NASA Astrophysics Data System (ADS)

Pazder, John; Fournier, Paul; Pawluczyk, Rafal; van Kooten, Maaike

2014-07-01

We report results of the extensive development work done on the 270-m optical fiber link for the GRACES project and a preliminary investigations into a high numerical aperture fiber for astronomy. The Gemini Remote Access CFHT ESPaDOnS Spectrograph (GRACES) is an instrumentation experiment to link ESPaDOnS, a bench-mounted highresolution optical spectrograph at CFHT, to the Gemini-North telescope with an optical fiber link. A 270-m fiber link with less than 14% Focal Ratio Degradation (FRD) has been developed jointly by HIA and FiberTech Optica for the experiment. A preliminary study has been conducted by HIA into a high numerical aperture fiber (0.26 numerical aperture) with the intended application of wide field optical spectrographs fiber fed from the telescope prime focus. The Laboratory test results of FRD, transmission, and stability for the GRACES fiber link and preliminary FRD measurements of the high numerical aperture fiber tests are reported.

A preliminary demonstration of "virtual warehousing" and cross-docking technique with active RFID combined with asset tracking equipment.

DOT National Transportation Integrated Search

2010-11-01

The University of Denvers Intermodal Transportation Institute and System Planning : Corporations GlobalTrak system have successfully demonstrated the integration of GPS : tracking and active RFID monitoring of simulated cargo of pallet and cart...

Addicted to Pain: A Preliminary Model of Sexual Masochism as Addiction.

PubMed

Kurt, Holly; Ronel, Natti

2017-11-01

An exploratory, qualitative, phenomenological study focused on the experience of pain while participating in sexual masochistic acts. Semi-structured interviews were conducted with nine individuals (four female, five male) who regularly participate in sexually masochistic acts and point to pain as central to their experience. Qualitative analysis of the data revealed several key characteristics of the participant's experience: the first time, intoxication, craving and withdrawal, tolerance, pain as control, and the pain inducing partner. The findings indicate that the way pain is experienced while mitigated through masochistic behavior creates an addictive process that coincides with a chronic behavioral spin contextualization. This article presents a preliminary model of addiction to physical pain in light of the Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) definition of substance-related and addictive disorders and the behavioral spin theory.

Mechatronic description of a laser autoguided vehicle for greenhouse operations.

PubMed

Sánchez-Hermosilla, Julián; González, Ramón; Rodríguez, Francisco; Donaire, Julián G

2013-01-08

This paper presents a novel approach for guiding mobile robots inside greenhouses demonstrated by promising preliminary physical experiments. It represents a comprehensive attempt to use the successful principles of AGVs (auto-guided vehicles) inside greenhouses, but avoiding the necessity of modifying the crop layout, and avoiding having to bury metallic pipes in the greenhouse floor. The designed vehicle can operate different tools, e.g., a spray system for applying plant-protection product, a lifting platform to reach the top part of the plants to perform pruning and harvesting tasks, and a trailer to transport fruits, plants, and crop waste. Regarding autonomous navigation, it follows the idea of AGVs, but now laser emitters are used to mark the desired route. The vehicle development is analyzed from a mechatronic standpoint (mechanics, electronics, and autonomous control).

Finding Your Way™: a collaborative approach to increase awareness of missing person events among persons with dementia.

PubMed

Hillier, Loretta M; Harvey, David; Conway, Cathy; Hunt, Jocelyn; Hoffman, Ron

2016-04-01

To describe an innovative community-wide program aimed at increasing awareness of risks of missing person events among persons with dementia targeting various cultural groups and to present preliminary evaluation findings. Review of program records to describe program implementation and a community partner survey. Over 23 months, 386 partnerships were established to implement the program; 941 awareness-raising sessions were conducted reaching 23,495 individuals. There is an upward trend in number of sessions conducted in various languages and attendance. Community partners' (>85%) responded positively to the program and consultation process. This partnership experience demonstrates the effectiveness of a collaborative approach to the development and widespread dissemination of information and resource materials aimed at ensuring the safety of a vulnerable population.

Process analysis of recycled thermoplasts from consumer electronics by laser-induced plasma spectroscopy.

PubMed

Fink, Herbert; Panne, Ulrich; Niessner, Reinhard

2002-09-01

An experimental setup for direct elemental analysis of recycled thermoplasts from consumer electronics by laser-induced plasma spectroscopy (LIPS, or laser-induced breakdown spectroscopy, LIBS) was realized. The combination of a echelle spectrograph, featuring a high resolution with a broad spectral coverage, with multivariate methods, such as PLS, PCR, and variable subset selection via a genetic algorithm, resulted in considerable improvements in selectivity and sensitivity for this complex matrix. With a normalization to carbon as internal standard, the limits of detection were in the ppm range. A preliminary pattern recognition study points to the possibility of polymer recognition via the line-rich echelle spectra. Several experiments at an extruder within a recycling plant demonstrated successfully the capability of LIPS for different kinds of routine on-line process analysis.

Application Of The Excimer Laser To Area Recontouring Of The Cornea

NASA Astrophysics Data System (ADS)

Yoder, Paul R.; Telfair, William B.; Warner, John W.; Martin, Clifford A.; L'Esperance, Francis A.

1989-04-01

Excimer lasers operating at 193 nm are being used experimentally in a special type of materials processing wherein the central portion of the anterior surface of the human cornea is selectively ablated so as to change its refractive power and, hopefully, improve impaired vision. Research to date has demonstrated recontouring as a potential means for reducing myopia and hyperopia of cadaver eyes while studies of ablations on the corneas of living monkeys and of blind human volunteers show promise of prompt and successful healing. The procedure has also shown merit in removing superficial scars from the corneal surface. In this paper, we describe the electro-optical system used to deliver the UV laser beam in these experiments and report some preliminary results of the ablation studies.

Selective removal of organics for water reclamation

NASA Technical Reports Server (NTRS)

Murphy, Oliver J.; Hitchens, G. Duncan

1989-01-01

Electrolysis has been investigated as a means of purifying waste water. The feasibility of the direct electrochemical oxidation of urea has been demonstrated. Urea levels were reduced from 1200 ppm to 1 ppm forming the basis for a new approach to urine purification where the only consumable is electrical energy. Preliminary estimates of the energy requirements are 270 W/hr per liter of urine. Urea oxidation rates of around 350 mg urea/hr/m2 were observed. It is anticipated that a 1 m2 geometric area of electrode could treat urine for a crew of several persons. The low levels of organic contaminants resulting from this treatment indicate that the approach may have an impact as a post treatment process. Experiments are planned to investigate this later possibility.

Time course of anger and other emotions in women with borderline personality disorder: a preliminary study.

PubMed

Jacob, Gitta A; Guenzler, Cindy; Zimmermann, Sabine; Scheel, Corinna N; Rüsch, Nicolas; Leonhart, Rainer; Nerb, Josef; Lieb, Klaus

2008-09-01

Borderline personality disorder (BPD) is characterized by emotional dysregulation including strong emotional reactions to emotional stimuli and a slow return to baseline emotions. Difficulties controlling anger are particularly prominent in BPD. To experimentally test emotional dysregulation with a special focus on anger, we investigated whether a standardized anger induction by a short story caused stronger and prolonged anger reactions in women with BPD (n=27) as compared to female healthy controls (n=26) and whether other emotions were affected by the anger induction. Although the anger reaction was not stronger in the BPD group, it was significantly prolonged. The BPD group showed also stronger negative emotions over the whole experiment. The study is the first to demonstrate prolonged anger reactions in BPD patients in an experimental setting.

Diamond field emitter array cathodes and possibilities for employing additive manufacturing for dielectric laser accelerating structures

DOE Office of Scientific and Technical Information (OSTI.GOV)

Simakov, Evgenya Ivanovna; Andrews, Heather Lynn; Herman, Matthew Joseph

2016-09-20

These are slides for a presentation at Stanford University. The outline is as follows: Motivation: customers for compact accelerators, LANL's technologies for laser acceleration, DFEA cathodes, and additive manufacturing of micron-size structures. Among the stated conclusions are the following: preliminary study identified DFEA cathodes as promising sources for DLAs--high beam current and small emittance; additive manufacturing with Nanoscribe Professional GT can produce structures with the right scale features for a DLA operating at micron wavelengths (fabrication tolerances need to be studied, DLAs require new materials). Future plans include DLA experiment with a beam produced by the DFEA cathode with fieldmore » emission, demonstration of photoemission from DFEAs, and new structures to print and test.« less

A Dual Modality System for Simultaneous Fluorescence and Positron Emission Tomography Imaging of Small Animals

NASA Astrophysics Data System (ADS)

Liu, Shuangquan; Zhang, Bin; Wang, Xin; Li, Lin; Chen, Yan; Liu, Xin; Liu, Fei; Shan, Baoci; Bai, Jing

2011-02-01

A dual-modality imaging system for simultaneous fluorescence molecular tomography (FMT) and positron emission tomography (PET) of small animals has been developed. The system consists of a noncontact 360°-projection FMT module and a flat panel detector pair based PET module, which are mounted orthogonally for the sake of eliminating cross interference. The FMT images and PET data are simultaneously acquired by employing dynamic sampling mode. Phantom experiments, in which the localization and range of radioactive and fluorescence probes are exactly indicated, have been carried out to verify the feasibility of the system. An experimental tumor-bearing mouse is also scanned using the dual-modality simultaneous imaging system, the preliminary fluorescence tomographic images and PET images demonstrate the in vivo performance of the presented dual-modality system.

Simultaneous measurement of breathing rate and heart rate using a microbend multimode fiber optic sensor

NASA Astrophysics Data System (ADS)

Chen, Zhihao; Lau, Doreen; Teo, Ju Teng; Ng, Soon Huat; Yang, Xiufeng; Kei, Pin Lin

2014-05-01

We propose and demonstrate the feasibility of using a highly sensitive microbend multimode fiber optic sensor for simultaneous measurement of breathing rate (BR) and heart rate (HR). The sensing system consists of a transceiver, microbend multimode fiber, and a computer. The transceiver is comprised of an optical transmitter, an optical receiver, and circuits for data communication with the computer via Bluetooth. Comparative experiments conducted between the sensor and predicate commercial physiologic devices showed an accuracy of ±2 bpm for both BR and HR measurement. Our preliminary study of simultaneous measurement of BR and HR in a clinical trial conducted on 11 healthy subjects during magnetic resonance imaging (MRI) also showed very good agreement with measurements obtained from conventional MR-compatible devices.

Spectral-spatial classification for noninvasive cancer detection using hyperspectral imaging

NASA Astrophysics Data System (ADS)

Lu, Guolan; Halig, Luma; Wang, Dongsheng; Qin, Xulei; Chen, Zhuo Georgia; Fei, Baowei

2014-10-01

Early detection of malignant lesions could improve both survival and quality of life of cancer patients. Hyperspectral imaging (HSI) has emerged as a powerful tool for noninvasive cancer detection and diagnosis, with the advantage of avoiding tissue biopsy and providing diagnostic signatures without the need of a contrast agent in real time. We developed a spectral-spatial classification method to distinguish cancer from normal tissue on hyperspectral images. We acquire hyperspectral reflectance images from 450 to 900 nm with a 2-nm increment from tumor-bearing mice. In our animal experiments, the HSI and classification method achieved a sensitivity of 93.7% and a specificity of 91.3%. The preliminary study demonstrated that HSI has the potential to be applied in vivo for noninvasive detection of tumors.

Dimorphous expressions of positive emotion: displays of both care and aggression in response to cute stimuli.

PubMed

Aragón, Oriana R; Clark, Margaret S; Dyer, Rebecca L; Bargh, John A

2015-03-01

Extremely positive experiences, and positive appraisals thereof, produce intense positive emotions that often generate both positive expressions (e.g., smiles) and expressions normatively reserved for negative emotions (e.g., tears). We developed a definition of these dimorphous expressions and tested the proposal that their function is to regulate emotions. We showed that individuals who express emotions in this dimorphous manner do so as a general response across a variety of emotionally provoking situations, which suggests that these expressions are responses to intense positive emotion rather than unique to one particular situation. We used cute stimuli (an elicitor of positive emotion) to demonstrate both the existence of these dimorphous expressions and to provide preliminary evidence of their function as regulators of emotion. © The Author(s) 2015.

Electrolytic decontamination of conductive materials for hazardous waste management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wedman, D.E.; Martinez, H.E.; Nelson, T.O.

1996-12-31

Electrolytic removal of plutonium and americium from stainless steel and uranium surfaces has been demonstrated. Preliminary experiments were performed on the electrochemically based decontamination of type 304L stainless steel in sodium nitrate solutions to better understand the metal removal effects of varying cur-rent density, pH, and nitrate concentration parameters. Material removal rates and changes in surface morphology under these varying conditions are reported. Experimental results indicate that an electropolishing step before contamination removes surface roughness, thereby simplifying later electrolytic decontamination. Sodium nitrate based electrolytic decontamination produced the most uniform stripping of material at low to intermediate pH and at sodiummore » nitrate concentrations of 200 g L{sup -1} and higher. Stirring was also observed to increase the uniformity of the stripping process.« less

State of the art in biobehavioral approaches to the management of chronic pain in childhood

PubMed Central

Simons, Laura E; Basch, Molly C

2016-01-01

Chronic pain in childhood is prevalent, persistent and significantly impactful on most domains of life. The chronic pain experience occurs within a complex biopsychosocial framework, with particular emphasis on the social context. Currently, psychological treatments involve a cognitive–behavioral therapy treatment plan, providing some combination of psychoeducation, self-regulation training, maladaptive cognition identification, behavioral exposure and parent involvement. New treatment areas are emerging, such as group- and internet-based cognitive–behavioral therapy, motivational interviewing, comorbid obesity intervention and intensive multidisciplinary rehabilitation. Preliminary studies of emerging treatments demonstrate encouraging results; however, treatment effectiveness hinges on accurate matching of patient to treatment modality. Overall, the current direction of the field promises many innovative breakthroughs to ameliorate suffering in youth with chronic pain. PMID:26678858

Integrated image presentation of transmission and fluorescent X-ray CT using synchrotron radiation

NASA Astrophysics Data System (ADS)

Zeniya, T.; Takeda, T.; Yu, Q.; Hasegawa, Y.; Hyodo, K.; Yuasa, T.; Hiranaka, Y.; Itai, Y.; Akatsuka, T.

2001-07-01

We have developed a computed tomography (CT) system with synchrotron radiation (SR) to detect fluorescent X-rays and transmitted X-rays simultaneously. Both SR transmission X-ray CT (SR-TXCT) and SR fluorescent X-ray CT (SR-FXCT) can describe cross-sectional images with high spatial and contrast resolutions as compared to conventional CT. TXCT gives morphological information and FXCT gives functional information of organs. So, superposed display system for SR-FXCT and SR-TXCT images has been developed for clinical diagnosis with higher reliability. Preliminary experiment with brain phantom was carried out and the superposition of both images was performed. The superposed SR-CT image gave us both functional and morphological information easily with high reliability, thus demonstrating the usefulness of this system.

Rapid analysis of controlled substances using desorption electrospray ionization mass spectrometry.

PubMed

Rodriguez-Cruz, Sandra E

2006-01-01

The recently developed technique of desorption electrospray ionization (DESI) has been applied to the rapid analysis of controlled substances. Experiments have been performed using a commercial ThermoFinnigan LCQ Advantage MAX ion-trap mass spectrometer with limited modifications. Results from the ambient sampling of licit and illicit tablets demonstrate the ability of the DESI technique to detect the main active ingredient(s) or controlled substance(s), even in the presence of other higher-concentration components. Full-scan mass spectrometry data provide preliminary identification by molecular weight determination, while rapid analysis using the tandem mass spectrometry (MS/MS) mode provides fragmentation data which, when compared to the laboratory-generated ESI-MS/MS spectral library, provide structural information and final identification of the active ingredient(s). The consecutive analysis of tablets containing different active components indicates there is no cross-contamination or interference from tablet to tablet, demonstrating the reliability of the DESI technique for rapid sampling (one tablet/min or better). Active ingredients have been detected for tablets in which the active component represents less than 1% of the total tablet weight, demonstrating the sensitivity of the technique. The real-time sampling of cannabis plant material is also presented.

Stress predicts brain changes in children: a pilot longitudinal study on youth stress, posttraumatic stress disorder, and the hippocampus.

PubMed

Carrion, Victor G; Weems, Carl F; Reiss, Allan L

2007-03-01

Does stress damage the brain? Studies of adults with posttraumatic stress disorder have demonstrated smaller hippocampal volumes when compared with the volumes of adults with no posttraumatic stress disorder. Studies of children with posttraumatic stress disorder have not replicated the smaller hippocampal findings in adults, which suggests that smaller hippocampal volume may be caused by neurodevelopmental experiences with stress. Animal research has demonstrated that the glucocorticoids secreted during stress can be neurotoxic to the hippocampus, but this has not been empirically demonstrated in human samples. We hypothesized that cortisol volumes would predict hippocampal volume reduction in patients with posttraumatic symptoms. We report data from a pilot longitudinal study of children (n = 15) with history of maltreatment who underwent clinical evaluation for posttraumatic stress disorder, cortisol, and neuroimaging. Posttraumatic stress disorder symptoms and cortisol at baseline predicted hippocampal reduction over an ensuing 12- to 18-month interval. Results from this pilot study suggest that stress is associated with hippocampal reduction in children with posttraumatic stress disorder symptoms and provide preliminary human evidence that stress may indeed damage the hippocampus. Additional studies seem to be warranted.

Point-source helicity injection for ST plasma startup in Pegasus

NASA Astrophysics Data System (ADS)

Redd, A. J.; Battaglia, D. J.; Bongard, M. W.; Fonck, R. J.; Schlossberg, D. J.

2009-11-01

Plasma current guns are used as point-source DC helicity injectors for forming non-solenoidal tokamak plasmas in the Pegasus Toroidal Experiment. Discharges driven by this injection scheme have achieved Ip>= 100 kA using Iinj<= 4 kA. They form at the outboard midplane, transition to a tokamak-like equilibrium, and continue to grow inward as Ip increases due to helicity injection and outer- PF induction. The maximum Ip is determined by helicity balance (injection rate vs resistive dissipation) and a Taylor relaxation limit, in which Ip√ITF Iinj/w, where w is the radial thickness of the gun-driven edge. Preliminary experiments tentatively confirm these scalings with ITF, Iinj, and w, increasing confidence in this simple relaxation model. Adding solenoidal inductive drive during helicity injection can push Ip up to, but not beyond, the predicted relaxation limit, demonstrating that this is a hard performance limit. Present experiments are focused on increasing the injection voltage (i.e., helicity injection rate) and reducing w. Near-term goals are to further test scalings predicted by the simple relaxation model and to study in detail the observed bursty n=1 activity correlated with rapid increases in Ip.

User needs, benefits and integration of robotic systems in a space station laboratory

NASA Technical Reports Server (NTRS)

Farnell, K. E.; Richard, J. A.; Ploge, E.; Badgley, M. B.; Konkel, C. R.; Dodd, W. R.

1989-01-01

The methodology, results and conclusions of the User Needs, Benefits, and Integration Study (UNBIS) of Robotic Systems in the Space Station Microgravity and Materials Processing Facility are summarized. Study goals include the determination of user requirements for robotics within the Space Station, United States Laboratory. Three experiments were selected to determine user needs and to allow detailed investigation of microgravity requirements. A NASTRAN analysis of Space Station response to robotic disturbances, and acceleration measurement of a standard industrial robot (Intelledex Model 660) resulted in selection of two ranges of low gravity manipulation: Level 1 (10-3 to 10-5 G at greater than 1 Hz.) and Level 2 (less than = 10-6 G at 0.1 Hz). This included an evaluation of microstepping methods for controlling stepper motors and concluded that an industrial robot actuator can perform milli-G motion without modification. Relative merits of end-effectors and manipulators were studied in order to determine their ability to perform a range of tasks related to the three low gravity experiments. An Effectivity Rating was established for evaluating these robotic system capabilities. Preliminary interface requirements were determined such that definition of requirements for an orbital flight demonstration experiment may be established.

Shock wave perturbation decay in granular materials

DOE PAGES

Vogler, Tracy J.

2015-11-05

A technique in which the evolution of a perturbation in a shock wave front is monitored as it travels through a sample is applied to granular materials. Although the approach was originally conceived as a way to measure the viscosity of the sample, here it is utilized as a means to probe the deviatoric strength of the material. Initial results for a tungsten carbide powder are presented that demonstrate the approach is viable. Simulations of the experiments using continuum and mesoscale modeling approaches are used to better understand the experiments. The best agreement with the limited experimental data is obtainedmore » for the mesoscale model, which has previously been shown to give good agreement with planar impact results. The continuum simulations indicate that the decay of the perturbation is controlled by material strength but is insensitive to the compaction response. Other sensitivities are assessed using the two modeling approaches. The simulations indicate that the configuration used in the preliminary experiments suffers from certain artifacts and should be modified to remove them. As a result, the limitations of the current instrumentation are discussed, and possible approaches to improve it are suggested.« less

Special Education Paraprofessionals in District Context

ERIC Educational Resources Information Center

Howley, Craig; Howley, Aimee; Telfer, Deborah

2017-01-01

This survey research investigated the experience of Ohio districts using paraprofessionals assigned to special education students. This study provides a unique statewide description of district experience. Based on themes from the literature and preliminary conversations with educational practitioners in Ohio, the survey conceptualized district…

Experiences of four parents with physical therapy and early mobility of their children in a pediatric critical care unit: A case series.

PubMed

Parisien, Rachel B; Gillanders, Kirstie; Hennessy, Erin K; Herterich, Lisa; Saunders, Kendra; Lati, Jamil; Dos Santos, Stephanie; Hassall, Alison; O'Brien, Kelly K

2016-05-31

The aim of this study was to conduct a preliminary investigation into parents' experiences of physical therapy and early mobility (EM) for their children in a pediatric critical care unit (PCCU). We conducted a series of four qualitative case studies using in-depth semi-structured face-to-face interviews. We recruited parents of children who had undergone surgery and received at least one EM physical therapy intervention while intubated. We conducted a thematic analysis of transcribed interviews to illuminate the factors that influenced EM experiences. Four parents participated in the study. We developed an overview of Parental Experiences with Physical Therapy and Early Mobility in a PCCU, which includes four themes that parents believed influenced their experiences: (1) environmental factors; (2) awareness of physical therapist and health care professional (HCP) roles; (3) communication among parents and HCPs; and (4) parental participation in their child's EM, within the overarching parental experiences in the PCCU. This study affords a preliminary understanding of parents' experiences with physical therapy and EM in a PCCU setting. Results provide an important foundation for future research on mobility in the context of pediatric critical care research and practice.

Preliminary design of a redundant strapped down inertial navigation unit using two-degree-of-freedom tuned-gimbal gyroscopes

NASA Technical Reports Server (NTRS)

1976-01-01

This redundant strapdown INS preliminary design study demonstrates the practicality of a skewed sensor system configuration by means of: (1) devising a practical system mechanization utilizing proven strapdown instruments, (2) thoroughly analyzing the skewed sensor redundancy management concept to determine optimum geometry, data processing requirements, and realistic reliability estimates, and (3) implementing the redundant computers into a low-cost, maintainable configuration.

Energy Efficient Engine: Control system preliminary definition report

NASA Technical Reports Server (NTRS)

Howe, David C.

1986-01-01

The object of the Control Preliminary Definition Program was to define a preliminary control system concept as a part of the Energy Efficient Engine program. The program was limited to a conceptual definition of a full authority digital electronic control system. System requirements were determined and a control system was conceptually defined to these requirements. Areas requiring technological development were identified and a plan was established for implementing the identified technological features, including a control technology demonstration. A significant element of this program was a study of the potential benefits of closed-loop active clearance control, along with laboratory tests of candidate clearance sensor elements for a closed loop system.

Passive exposure of Earth radiation budget experiment components. LDEF experiment AO-147: Post-flight examinations and tests

NASA Technical Reports Server (NTRS)

Hickey, John R.

1992-01-01

The flight spare sensors of the Earth Radiation Budget (ERB) experiment of the Nimbus 6 and 7 missions were flown aboard the LDEF. The preliminary post retrieval examination and test results are presented here for the sensor windows and filters, the thermopile sensors and a cavity radiometer.

HEBS and Binary 1-sinc masks simulations, HCIT experiments and results

NASA Technical Reports Server (NTRS)

Balasubramanian, Bala K.; Hoppe, Dan; Wilson, Dan; Echternach, Pierre; Trauger, John; Halverson, Peter; Niessner, Al; Shi, Fang; Lowman, Andrew

2005-01-01

Based on preliminary experiments and results with a binary 1-sinc mask in the HCIT early in August 2004, we planned for a detailed experiment to compare the performance of HEBS and Binary masks under nearly identical conditions in the HCIT. This report details the design and fabrication of the masks, simulated predictions, and experimental results.

Student Participation in Ecological Research: Preliminary Insights from Students' Experiences in the Smoky Mountains

ERIC Educational Resources Information Center

Pacifici, Lara B.; Miller, Craig; Thomson, Norman

2009-01-01

Students participating in summer research internships at the Great Smoky Mountain National Park kept electronic journals to document their experiences. We used a combined content analysis to quantify the responses from the students in particular areas of interest and to understand the essence of experiences from the explanations provided in their…

Learner-Centered Blogging: A Preliminary Investigation of EFL Student Writers' Experience

ERIC Educational Resources Information Center

Lin, Ming Huei

2015-01-01

This study aims to investigate the effectiveness of integrating a learner-centered blogging approach into the EFL writing classroom in Taiwan. For this purpose, a 16-week experiment was conducted, involving an intact class of 18 university-level Taiwanese EFL student writers. During the experiment, the participants first created their own blogs on…

A preliminary 6 DOF attitude and translation control system design for Starprobe

NASA Technical Reports Server (NTRS)

Mak, P.; Mettler, E.; Vijayarahgavan, A.

1981-01-01

The extreme thermal environment near perihelion and the high-accuracy gravitational science experiments impose unique design requirements on various subsystems of Starprobe. This paper examines some of these requirements and their impact on the preliminary design of a six-degree-of-freedom attitude and translational control system. Attention is given to design considerations, the baseline attitude/translational control system, system modeling, and simulation studies.

Preliminary Evaluation Of Commercial Supercapacitors For Space Applications

NASA Astrophysics Data System (ADS)

Gineste, Valery; Loup, Didier; Mattesco, Patrick; Neugnot, Nicolas

2011-10-01

Supercapacitors are identified since years as a new technology enabling energy storage together with high power delivery capability to the system. A recent ESA study [1] led by Astrium has demonstrated the interest of these devices for space application, providing that reliability and end of life performances are demonstrated. A realistic commercial on the shelf (COTS) approach (or with limited design modification approved by potential suppliers) has been favoured (as for batteries). This paper presents preliminary test results done by Astrium on COTS supercapacitors: accelerated life tests, calendar life tests, technology analyses. Based on these results, assessment and lessons learnt are drawn in view of future exhaustive supercapacitor validation and future qualification.

The Thirty Gigahertz Instrument Receiver for the QUIJOTE Experiment: Preliminary Polarization Measurements and Systematic-Error Analysis.

PubMed

Casas, Francisco J; Ortiz, David; Villa, Enrique; Cano, Juan L; Cagigas, Jaime; Pérez, Ana R; Aja, Beatriz; Terán, J Vicente; de la Fuente, Luisa; Artal, Eduardo; Hoyland, Roger; Génova-Santos, Ricardo

2015-08-05

This paper presents preliminary polarization measurements and systematic-error characterization of the Thirty Gigahertz Instrument receiver developed for the QUIJOTE experiment. The instrument has been designed to measure the polarization of Cosmic Microwave Background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. Two kinds of linearly polarized input signals have been used as excitations in the polarimeter measurement tests in the laboratory; these show consistent results in terms of the Stokes parameters obtained. A measurement-based systematic-error characterization technique has been used in order to determine the possible sources of instrumental errors and to assist in the polarimeter calibration process.

Preliminary Investigation of Cyclic Behavior at SHADOZ Sites Between the Equator and 5 deg S Latitude

NASA Technical Reports Server (NTRS)

Schmidlin, F. J.

2009-01-01

Investigation of cyclic behavior of temperature and ozone data from five SHADOZ sites between the Equator and 5degS Latitude (Nairobi, Ascension Island, Natal, San Crystobal, and Watukoset) reveal an amazing array of oscillations. In particular, eight years of measurements (1998-2007) reveal changes such as decreasing amounts of ozone at some pressure levels and/or sites, while other levels and/or sites experience increasing ozone. Temperature changes of 1-2 C occur that also experience irregular oscillations. This study is preliminary and only concentrates on the 250-, 200-, 100-, 70-, and 50-hPa pressure surfaces. Surfaces existing below and above the tropopause behave differently.

Preliminary Experiments for the Assessment of V/W-band Links for Space-Earth Communications

NASA Technical Reports Server (NTRS)

Nessel, James A.; Acosta, Roberto J.; Miranda, Felix A.

2013-01-01

Since September 2012, NASA Glenn Research Center has deployed a microwave profiling radiometer at White Sands, NM, to estimate atmospheric propagation effects on communications links in the V and W bands (71-86GHz). Estimates of attenuation statistics in the millimeter wave due to gaseous and cloud components of the atmosphere show good agreement with current ITU-R models, but fail to predict link performance in the presence of moderate to heavy rain rates, due to the inherent limitations of passive radiometry. Herein, we discuss the preliminary results of these measurements and describe a design for a terrestrial link experiment to validate/refine existing rain attenuation models in the V/Wbands.

Preliminary Experiments for the Assessment of VW-Band Links for Space-Earth Communications

NASA Technical Reports Server (NTRS)

Nessel, James A.; Acosta, Roberto J.; Miranda, Felix A.

2013-01-01

Since September 2012, NASA Glenn Research Center has deployed a microwave profiling radiometer at White Sands, NM, to estimate atmospheric propagation effects on communications links in the V and W bands (71-86GHz). Estimates of attenuation statistics in the millimeter wave due to gaseous and cloud components of the atmosphere show good agreement with current ITU-R models, but fail to predict link performance in the presence of moderate to heavy rain rates, due to the inherent limitations of passive radiometry. Herein, we discuss the preliminary results of these measurements and describe a design for a terrestrial link experiment to validaterefine existing rain attenuation models in the VW-bands.

[A new psycho-dermatology clinic in Israel: our first year experience].

PubMed

Orion, Edith; Ben-Avi, Orit

2011-01-01

Psychodermatology involves the interrelationships between the skin and the mind, especially when considering the formation and evolution of certain common skin conditions. It appears that 30-40% of dermatology patients suffer from certain psychological problems as defined by the ICD-10, in a way that influences their disease severity and progression, as well as their quality of Life. Treatment of such cases requires a multi-disciplinary approach and should involve both a dermatologist and a mental health specialist working together In this article, the authors summarize the preliminary experience of the first year of the only psychodermatology clinic in Israel in several decades, work methods and patients' characteristics and preliminary conclusions.

Biodegradable biliary stent implantation in the treatment of benign bilioplastic-refractory biliary strictures: preliminary experience.

PubMed

Mauri, Giovanni; Michelozzi, Caterina; Melchiorre, Fabio; Poretti, Dario; Tramarin, Marco; Pedicini, Vittorio; Solbiati, Luigi; Cornalba, Gianpaolo; Sconfienza, Luca Maria

2013-12-01

To evaluate feasibility, safety, and outcome of patients treated with biodegradable biliary stents for benign biliary stenosis refractory to other treatments. Between March 2011 and September 2012, ten patients (seven men, three women; age 59 ± 7 years) with recurrent cholangitis due to postsurgical biliary stricture, previous multiple unsuccessful (two to five) bilioplasties, and unsuitability for surgical/endoscopic repair underwent percutaneous implantation of a biodegradable biliary stent. Patients were followed-up clinically and with ultrasound at 1, 3 and 6 months, and then at 6-month intervals. Stent implantation was always feasible. No immediate major or minor complications occurred. In all patients, 48-h cholangiographic control demonstrated optimal stent positioning and stenosis resolution. In a median follow-up time of 16.5 months (25th-75th percentiles = 11-20.25 months) no further invasive treatment was needed. Three patients experienced transient episodes of cholangitis. Neither re-stenosis nor dilatation of the biliary tree was documented during follow-up. No stent was visible at the 6-month follow-up. Percutaneous placement of biodegradable biliary stents represents a new option in treating benign biliary stenoses refractory to treatment with bilioplasty. This technique seems to be feasible, effective and free from major complications. Further investigations are warranted to confirm our preliminary results.

Ayahuasca-assisted therapy for addiction: results from a preliminary observational study in Canada.

PubMed

Thomas, Gerald; Lucas, Philippe; Capler, N Rielle; Tupper, Kenneth W; Martin, Gina

2013-03-01

This paper reports results from a preliminary observational study of ayahuasca-assisted treatment for problematic substance use and stress delivered in a rural First Nations community in British Columbia, Canada. The "Working with Addiction and Stress" retreats combined four days of group counselling with two expert-led ayahuasca ceremonies. This study collected pre-treatment and six months follow-up data from 12 participants on several psychological and behavioral factors related to problematic substance use, and qualitative data assessing the personal experiences of the participants six months after the retreat. Statistically significant (p < 0.05) improvements were demonstrated for scales assessing hopefulness, empowerment, mindfulness, and quality of life meaning and outlook subscales. Self-reported alcohol, tobacco and cocaine use declined, although cannabis and opiate use did not; reported reductions in problematic cocaine use were statistically significant. All study participants reported positive and lasting changes from participating in the retreats. This form of ayahuasca-assisted therapy appears to be associated with statistically significant improvements in several factors related to problematic substance use among a rural aboriginal population. These findings suggest participants may have experienced positive psychological and behavioral changes in response to this therapeutic approach, and that more rigorous research of ayahuasca-assisted therapy for problematic substance use is warranted.

X-ray transparent microfluidic chips for high-throughput screening and optimization of in meso membrane protein crystallization

PubMed Central

Schieferstein, Jeremy M.; Pawate, Ashtamurthy S.; Wan, Frank; Sheraden, Paige N.; Broecker, Jana; Ernst, Oliver P.; Gennis, Robert B.

2017-01-01

Elucidating and clarifying the function of membrane proteins ultimately requires atomic resolution structures as determined most commonly by X-ray crystallography. Many high impact membrane protein structures have resulted from advanced techniques such as in meso crystallization that present technical difficulties for the set-up and scale-out of high-throughput crystallization experiments. In prior work, we designed a novel, low-throughput X-ray transparent microfluidic device that automated the mixing of protein and lipid by diffusion for in meso crystallization trials. Here, we report X-ray transparent microfluidic devices for high-throughput crystallization screening and optimization that overcome the limitations of scale and demonstrate their application to the crystallization of several membrane proteins. Two complementary chips are presented: (1) a high-throughput screening chip to test 192 crystallization conditions in parallel using as little as 8 nl of membrane protein per well and (2) a crystallization optimization chip to rapidly optimize preliminary crystallization hits through fine-gradient re-screening. We screened three membrane proteins for new in meso crystallization conditions, identifying several preliminary hits that we tested for X-ray diffraction quality. Further, we identified and optimized the crystallization condition for a photosynthetic reaction center mutant and solved its structure to a resolution of 3.5 Å. PMID:28469762

Fusing Panchromatic and SWIR Bands Based on Cnn - a Preliminary Study Over WORLDVIEW-3 Datasets

NASA Astrophysics Data System (ADS)

Guo, M.; Ma, H.; Bao, Y.; Wang, L.

2018-04-01

The traditional fusion methods are based on the fact that the spectral ranges of the Panchromatic (PAN) and multispectral bands (MS) are almost overlapping. In this paper, we propose a new pan-sharpening method for the fusion of PAN and SWIR (short-wave infrared) bands, whose spectral coverages are not overlapping. This problem is addressed with a convolutional neural network (CNN), which is trained by WorldView-3 dataset. CNN can learn the complex relationship among bands, and thus alleviate spectral distortion. Consequently, in our network, we use the simple three-layer basic architecture with 16 × 16 kernels to conduct the experiment. Every layer use different receptive field. The first two layers compute 512 feature maps by using the 16 × 16 and 1 × 1 receptive field respectively and the third layer with a 8 × 8 receptive field. The fusion results are optimized by continuous training. As for assessment, four evaluation indexes including Entropy, CC, SAM and UIQI are selected built on subjective visual effect and quantitative evaluation. The preliminary experimental results demonstrate that the fusion algorithms can effectively enhance the spatial information. Unfortunately, the fusion image has spectral distortion, it cannot maintain the spectral information of the SWIR image.

System Synthesis in Preliminary Aircraft Design using Statistical Methods

NASA Technical Reports Server (NTRS)

DeLaurentis, Daniel; Mavris, Dimitri N.; Schrage, Daniel P.

1996-01-01

This paper documents an approach to conceptual and preliminary aircraft design in which system synthesis is achieved using statistical methods, specifically design of experiments (DOE) and response surface methodology (RSM). These methods are employed in order to more efficiently search the design space for optimum configurations. In particular, a methodology incorporating three uses of these techniques is presented. First, response surface equations are formed which represent aerodynamic analyses, in the form of regression polynomials, which are more sophisticated than generally available in early design stages. Next, a regression equation for an overall evaluation criterion is constructed for the purpose of constrained optimization at the system level. This optimization, though achieved in a innovative way, is still traditional in that it is a point design solution. The methodology put forward here remedies this by introducing uncertainty into the problem, resulting a solutions which are probabilistic in nature. DOE/RSM is used for the third time in this setting. The process is demonstrated through a detailed aero-propulsion optimization of a high speed civil transport. Fundamental goals of the methodology, then, are to introduce higher fidelity disciplinary analyses to the conceptual aircraft synthesis and provide a roadmap for transitioning from point solutions to probabalistic designs (and eventually robust ones).

Science-based HRA: experimental comparison of operator performance to IDAC (Information-Decision-Action Crew) simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shirley, Rachel; Smidts, Carol; Boring, Ronald

Information-Decision-Action Crew (IDAC) operator model simulations of a Steam Generator Tube Rupture are compared to student operator performance in studies conducted in the Ohio State University’s Nuclear Power Plant Simulator Facility. This study is presented as a prototype for conducting simulator studies to validate key aspects of Human Reliability Analysis (HRA) methods. Seven student operator crews are compared to simulation results for crews designed to demonstrate three different decision-making strategies. The IDAC model used in the simulations is modified slightly to capture novice behavior rather that expert operators. Operator actions and scenario pacing are compared. A preliminary review of availablemore » performance shaping factors (PSFs) is presented. After the scenario in the NPP Simulator Facility, student operators review a video of the scenario and evaluate six PSFs at pre-determined points in the scenario. This provides a dynamic record of the PSFs experienced by the OSU student operators. In this preliminary analysis, Time Constraint Load (TCL) calculated in the IDAC simulations is compared to TCL reported by student operators. We identify potential modifications to the IDAC model to develop an “IDAC Student Operator Model.” This analysis provides insights into how similar experiments could be conducted using expert operators to improve the fidelity of IDAC simulations.« less

The Northrop Grumman External Occulter Testbed: Preliminary Results

NASA Astrophysics Data System (ADS)

Lo, Amy; Glassman, T.; Lillie, C.

2007-05-01

We have built a subscale testbed to demonstrate and validate the performance of the New Worlds Observer (NWO), a terrestrial planet finder external-occulter mission concept. The external occulter concept allows observations of nearby exo-Earths using two spacecraft: one carrying an occulter that is tens of meters in diameter and the other carrying a generic space telescope. The occulter is completely opaque, resembling a flower, with petals having a hypergaussian profile that enable 10-10 intensity suppression of stars that potentially harbor terrestrial planets. The baseline flight NWO system has a 30 meter occulter flying 30,000 km in front of a 4 meter class telescope. Testing the flight configuration on the ground is not feasible, so we have matched the Fresnel number of the flight configuration ( 10) using a subscale occulter. Our testbed consists of an 80 meter length evacuated tube, with a high precision occulter in the center of the tube. The occulter is 4 cm in diameter, manufactured with ¼ micron metrological accuracy and less than 2 micron tip truncation. This mimics a 30 meter occulter with millimeter figure accuracy and less than centimeter tip truncation. Our testbed is an evolving experiment, and we report here the first, preliminary, results using a single wavelength laser (532 nm) as the source.

Preliminary study on X-ray fluorescence computed tomography imaging of gold nanoparticles: Acceleration of data acquisition by multiple pinholes scheme

NASA Astrophysics Data System (ADS)

Sasaya, Tenta; Sunaguchi, Naoki; Seo, Seung-Jum; Hyodo, Kazuyuki; Zeniya, Tsutomu; Kim, Jong-Ki; Yuasa, Tetsuya

2018-04-01

Gold nanoparticles (GNPs) have recently attracted attention in nanomedicine as novel contrast agents for cancer imaging. A decisive tomographic imaging technique has not yet been established to depict the 3-D distribution of GNPs in an object. An imaging technique known as pinhole-based X-ray fluorescence computed tomography (XFCT) is a promising method that can be used to reconstruct the distribution of GNPs from the X-ray fluorescence emitted by GNPs. We address the acceleration of data acquisition in pinhole-based XFCT for preclinical use using a multiple pinhole scheme. In this scheme, multiple projections are simultaneously acquired through a multi-pinhole collimator with a 2-D detector and full-field volumetric beam to enhance the signal-to-noise ratio of the projections; this enables fast data acquisition. To demonstrate the efficacy of this method, we performed an imaging experiment using a physical phantom with an actual multi-pinhole XFCT system that was constructed using the beamline AR-NE7A at KEK. The preliminary study showed that the multi-pinhole XFCT achieved a data acquisition time of 20 min at a theoretical detection limit of approximately 0.1 Au mg/ml and at a spatial resolution of 0.4 mm.

Experiments in pilot decision-making during simulated low visibility approaches

NASA Technical Reports Server (NTRS)

Curry, R. E.; Lauber, J. K.; Billings, C. E.

1975-01-01

A simulation task is reported which incorporates both kinds of variables, informational and psychological, to successfully study pilot decision making behavior in the laboratory. Preliminary experiments in the measurement of decisions and the inducement of stress in simulated low visibility approaches are described.

The Structured Trauma-Related Experiences and Symptoms Screener (STRESS): Development and Preliminary Psychometrics.

PubMed

Grasso, Damion J; Felton, Julia W; Reid-Quiñones, Kathryn

2015-08-01

The Structured Trauma-Related Experiences and Symptoms Screener (STRESS) is a self-report instrument for youth of age 7-18 that inventories 25 adverse childhood experiences and potentially traumatic events and assesses symptoms of post-traumatic stress disorder using the revised criteria published in the Diagnostic and Statistical Manual for Mental Disorders, fifth edition (DSM-5). The STRESS can be administered by computer such that questions are read aloud and automatic scoring and feedback are provided. Data were collected on a sample of 229 children and adolescents of age 7-17 undergoing a forensic child abuse and neglect evaluation. The purpose of the current study was to examine preliminary psychometric characteristics of the computer-administered STRESS as well as its underlying factor structure in relation to the four-factor DSM-5 model. Results provide initial support for the use of the STRESS in assessing adverse and potentially traumatic experiences and traumatic stress in children and adolescents. © The Author(s) 2015.

Rocket observations of solar radiation during the eclipse of 26 February 1979

NASA Technical Reports Server (NTRS)

Bliss, H. M.; Smith, L. G.

1980-01-01

Three Nike Tomahawk rockets were launched in Red Lake, Ontario, one previous to, and two during, the total eclipse of the Sun, for the purpose of studying the atmosphere and its interaction with solar radiation. The method and preliminary results of three experiments that were used to measure solar radiation in the X-ray, Lyman-alpha, and visible parts of the spectrum are described. The instrumentation designed for this investigation is discussed as well as post-flight data processing techniques. The retrieved data were processed to some extent to verify that a valid representation of the solar radiation was obtained. The Lyman-alpha experiment yielded very good results, and preliminary data are included. The visible radiation experiment served as support for the other experiments and also functioned well. Due to a high level of energetic particles during the eclipse, the X-ray data were contaminated and are not presented. However, satellite observations indicate no appreciable level of X-rays from the Sun during the time of the eclipse.

Subjective experience of inner speech in aphasia: Preliminary behavioral relationships and neural correlates.

PubMed

Fama, Mackenzie E; Hayward, William; Snider, Sarah F; Friedman, Rhonda B; Turkeltaub, Peter E

2017-01-01

Many individuals with aphasia describe anomia with comments like "I know it but I can't say it." The exact meaning of such phrases is unclear. We hypothesize that at least two discrete experiences exist: the sense of (1) knowing a concept, but failing to find the right word, and (2) saying the correct word internally but not aloud (successful inner speech, sIS). We propose that sIS reflects successful lexical access; subsequent overt anomia indicates post-lexical output deficits. In this pilot study, we probed the subjective experience of anomia in 37 persons with aphasia. Self-reported sIS related to aphasia severity and phonological output deficits. In multivariate lesion-symptom mapping, sIS was associated with dorsal stream lesions, particularly in ventral sensorimotor cortex. These preliminary results suggest that people with aphasia can often provide meaningful insights about their experience of anomia and that reports of sIS relate to specific lesion locations and language deficits. Copyright © 2016 Elsevier Inc. All rights reserved.

Preliminary navigation accuracy analysis for the TDRSS Onboard Navigation System (TONS) experiment on EP/EUVE

NASA Technical Reports Server (NTRS)

Gramling, C. J.; Long, A. C.; Lee, T.; Ottenstein, N. A.; Samii, M. V.

1991-01-01

A Tracking and Data Relay Satellite System (TDRSS) Onboard Navigation System (TONS) is currently being developed by NASA to provide a high accuracy autonomous navigation capability for users of TDRSS and its successor, the Advanced TDRSS (ATDRSS). The fully autonomous user onboard navigation system will support orbit determination, time determination, and frequency determination, based on observation of a continuously available, unscheduled navigation beacon signal. A TONS experiment will be performed in conjunction with the Explorer Platform (EP) Extreme Ultraviolet Explorer (EUVE) mission to flight quality TONS Block 1. An overview is presented of TONS and a preliminary analysis of the navigation accuracy anticipated for the TONS experiment. Descriptions of the TONS experiment and the associated navigation objectives, as well as a description of the onboard navigation algorithms, are provided. The accuracy of the selected algorithms is evaluated based on the processing of realistic simulated TDRSS one way forward link Doppler measurements. The analysis process is discussed and the associated navigation accuracy results are presented.

Decision-Making in Flight with Different Convective Weather Information Sources: Preliminary Results

NASA Technical Reports Server (NTRS)

Latorella, Kara A.; Chamberlain, James P.

2004-01-01

This paper reports preliminary and partial results of a flight experiment to address how General Aviation (GA) pilots use weather cues to make flight decisions. This research presents pilots with weather cue conditions typically available to GA pilots in visual meteorological conditions (VMC) and instrument meteorological conditions (IMC) today, as well as in IMC with a Graphical Weather Information System (GWIS). These preliminary data indicate that both VMC and GWIS-augmented IMC conditions result in better confidence, information sufficiency and perceived performance than the current IMC condition. For all these measures, the VMC and GWIS-augmented conditions seemed to provide similar pilot support. These preliminary results are interpreted for their implications on GWIS display design, training, and operational use guidelines. Final experimental results will compare these subjective data with objective data of situation awareness and decision quality.

GRC-2010-C-01237

NASA Image and Video Library

2006-03-29

Fiber-Reinforced-Foam (FRF) Core Composite Sandwich Panel Concept for Advanced Composites Technologies Project - Preliminary Manufacturing Demonstration Articles for Ares V Payload Shroud Barrel Acreage Structure

GRC-2010-C-01234

NASA Image and Video Library

2006-03-29

Fiber-Reinforced-Foam (FRF) Core Composite Sandwich Panel Concept for Advanced Composites Technologies Project - Preliminary Manufacturing Demonstration Articles for Ares V Payload Shroud Barrel Acreage Structure

GRC-2010-C-01233

NASA Image and Video Library

2006-03-29

Fiber-Reinforced-Foam (FRF) Core Composite Sandwich Panel Concept for Advanced Composites Technologies Project - Preliminary Manufacturing Demonstration Articles for Ares V Payload Shroud Barrel Acreage Structure

Development of a biaxial compression device for biological samples: preliminary experimental results for a closed cell foam.

PubMed

Little, J P; Tevelen, G; Adam, C J; Evans, J H; Pearcy, M J

2009-07-01

Biological tissues are subjected to complex loading states in vivo and in order to define constitutive equations that effectively simulate their mechanical behaviour under these loads, it is necessary to obtain data on the tissue's response to multiaxial loading. Single axis and shear testing of biological tissues is often carried out, but biaxial testing is less common. We sought to design and commission a biaxial compression testing device, capable of obtaining repeatable data for biological samples. The apparatus comprised a sealed stainless steel pressure vessel specifically designed such that a state of hydrostatic compression could be created on the test specimen while simultaneously unloading the sample along one axis with an equilibrating tensile pressure. Thus a state of equibiaxial compression was created perpendicular to the long axis of a rectangular sample. For the purpose of calibration and commissioning of the vessel, rectangular samples of closed cell ethylene vinyl acetate (EVA) foam were tested. Each sample was subjected to repeated loading, and nine separate biaxial experiments were carried out to a maximum pressure of 204 kPa (30 psi), with a relaxation time of two hours between them. Calibration testing demonstrated the force applied to the samples had a maximum error of 0.026 N (0.423% of maximum applied force). Under repeated loading, the foam sample demonstrated lower stiffness during the first load cycle. Following this cycle, an increased stiffness, repeatable response was observed with successive loading. While the experimental protocol was developed for EVA foam, preliminary results on this material suggest that this device may be capable of providing test data for biological tissue samples. The load response of the foam was characteristic of closed cell foams, with consolidation during the early loading cycles, then a repeatable load-displacement response upon repeated loading. The repeatability of the test results demonstrated the ability of the test device to provide reproducible test data and the low experimental error in the force demonstrated the reliability of the test data.

Preliminary results toward injection locking of an incoherent laser array

NASA Technical Reports Server (NTRS)

Daher, J.

1986-01-01

The preliminary results of phase locking an incoherent laser array to a master source in an attempt to achieve coherent operation are presented. The techniques necessary to demonstrate phase locking are described along with some topics for future consideration. As expected, the results obtained suggest that injection locking of an array, where the spacing between adjacent longitudinal modes of its elements is significantly larger than the locking bandwidth, may not be feasible.

A preliminary look at AVE-SESAME 4 conducted on 9-10 May 1979

NASA Technical Reports Server (NTRS)

July, M.; Turner, R. E.

1980-01-01

This report contains information on data collected, symptotic conditions, and severe and unusual weather reported during the Atmospheric Variability Experiment Severe Environmental Storms and Mesoscale Experiment (AVE-SESAME) 4 period. The information provides researchers a look at conditions during the period.

Forest Herbicide Washoff From Foliar Applications

Treesearch

J.L. Michael; Kevin L. Talley; H.C. Fishburn

1992-01-01

Field and laboratory experiments were conducted to develop and test methods for determining washoff of foliar applied herbicides typically used in forestry in the South.Preliminary results show good agreement between results of laboratory methods used and observations from field experiments on actual precipitation events. Methods included application of...

Toward Machine Understanding of Information Quality.

ERIC Educational Resources Information Center

Tang, Rong; Ng, K. B.; Strzalkowski, Tomek; Kantor, Paul B.

2003-01-01

Reports preliminary results of a study to develop and automate new metrics for assessment of information quality in text documents, particularly in news. Through focus group studies, quality judgment experiments, and textual feature extraction and analysis, nine quality aspects were generated and applied in human assessments. Experiments were…

The Entrepreneurial Subjectivity of Successful Researchers

ERIC Educational Resources Information Center

Sinclair, Jennifer; Cuthbert, Denise; Barnacle, Robyn

2014-01-01

This article begins the work of examining what kind of doctoral experiences positively influence researcher development, and what other attributes may contribute to a successful research career. It reports preliminary findings from the analysis of survey responses by a sample of successful mid-career researchers. Positive doctoral experiences and…

A preliminary experiment to collect gas from a submarine gas plume

NASA Astrophysics Data System (ADS)

Aoyama, C.; Fukuoka, H.

2016-12-01

Thousands of gas plumes have been found on the sea floors around Japan. Most of them are associated with methane hydrates on seafloor surface and/or shallow subsurface, and those bubbles are consisting largely of methane. Concerns are emerging about large scale plumes may provide the highly efficient greenhouse gas to the atmosphere. A novel methodology is proposed in this study, to collect those gas bubbles in the plumes using membrane-made dome to reduce global greenhouse effect and to develop new energy resources. Experiment field is northeast offshore of the Sado Island, Niigata prefecture of Japan, where more than 40 gas plumes had been found, gushing out from rather shallower sea floor of 150 - 400 m depth. Authors will present the achievement obtained in the preliminary gas collection experiment which was performed in a gas plume in this sea area in March 2016.

ATS-6 - Preliminary results from the 13/18-GHz COMSAT Propagation Experiment

NASA Technical Reports Server (NTRS)

Hyde, G.

1975-01-01

The 13/18-GHz COMSAT Propagation Experiment (CPE) is reviewed, the data acquisition and processing are discussed, and samples of preliminary results are presented. The need for measurements of both hydrometeor-induced attenuation statistics and diversity effectiveness is brought out. The facilitation of the experiment - CPE dual frequency and diversity site location, the CPE ground transmit terminals, the CPE transponder on Applications Technology Satellite-6 (ATS-6), and the CPE receive and data acquisition system - is briefly examined. The on-line preprocessing of the received signal is reviewed, followed by a discussion of the off-line processing of this database to remove signal fluctuations not due to hydrometeors. Finally, samples of the results of first-level analysis of the resultant data for the 18-GHz diversity site near Boston, Mass., and for the dual frequency 13/18-GHz site near Detroit, Mich., are presented and discussed.

SLS-1 flight experiments preliminary significant results

NASA Technical Reports Server (NTRS)

1992-01-01

Spacelab Life Sciences-1 (SLS-1) is the first of a series of dedicated life sciences Spacelab missions designed to investigate the mechanisms involved in the physiological adaptation to weightlessness and the subsequent readaptation to 1 gravity (1 G). Hypotheses generated from the physiological effects observed during earlier missions led to the formulation of several integrated experiments to determine the underlying mechanisms responsible for the observed phenomena. The 18 experiments selected for flight on SLS-1 investigated the cardiovascular, cardiopulmonary, regulatory physiology, musculoskeletal, and neuroscience disciplines in both human and rodent subjects. The SLS-1 preliminary results gave insight to the mechanisms involved in the adaptation to the microgravity environment and readaptation when returning to Earth. The experimental results will be used to promote health and safety for future long duration space flights and, as in the past, will be applied to many biomedical problems encountered here on Earth.

Conjugating binary systems for spacecraft thermal control. Appendix C: Aeroassist Flight Experiment Carrier Vehicle preliminary stress analysis

NASA Technical Reports Server (NTRS)

Ingram, J. E.; Murray, T. O.

1989-01-01

An assessment of the static strength of the Aeroassist Flight Experiment (AFE) Carrier Vehicle is presented. The Carrier Vehicle is the structural component which provides the mounting platform for the experiments, on-board computers, batteries, and other black boxes. In addition, the Solid Rocket Motor (SRM), the Thrusters, and the Aerobrake are all attached directly to the Carrier Vehicle. The basic approach in this analysis was to develop a NASTRAN Finite Element Model as a parallel effort to the preliminary design, and to use the internal loads from this model to perform the stress analysis. The NASTRAN method of Inertial Relief was employed. This method involves either specifying a set of CG (center of gravity) accelerations or applying forces at the CG and representing the Carrier Vehicle and all its mounted devices with the proper stiffness and mass properties.

Protein crystal growth in microgravity

NASA Technical Reports Server (NTRS)

Rosenblum, William M.; Delucas, Lawrence J.; Wilson, William W.

1989-01-01

Major advances have been made in several of the experimental aspects of protein crystallography, leaving protein crystallization as one of the few remaining bottlenecks. As a result, it has become important that the science of protein crystal growth is better understood and that improved methods for protein crystallization are developed. Preliminary experiments with both small molecules and proteins indicate that microgravity may beneficially affect crystal growth. For this reason, a series of protein crystal growth experiments using the Space Shuttle was initiated. The preliminary space experiments were used to evolve prototype hardware that will form the basis for a more advanced system that can be used to evaluate effects of gravity on protein crystal growth. Various optical techniques are being utilized to monitor the crystal growth process from the incipient or nucleation stage and throughout the growth phase. The eventual goal of these studies is to develop a system which utilizes optical monitoring for dynamic control of the crystallization process.

[Experience in the use of equipment for ECG system analysis in municipal polyclinics].

PubMed

Bondarenko, A A

2006-01-01

Two electrocardiographs, an analog-digital electrocardiograph with preliminary analog filtering of signal and a smart cardiograph implemented as a PC-compatible device without preliminary analog filtering, are considered. Advantages and disadvantages of ECG systems based on artificial intelligence are discussed. ECG interpretation modes provided by the two electrocardiographs are considered. The reliability of automatic ECG interpretation is assessed. Problems of rational use of automated ECG processing systems are discussed.

Preliminary results on the search for the neutrinoless double beta decay of 130Te with the cuoricino experiment

DOE PAGES

Nucciotti, A.

2003-11-18

The search for neutrinoless double beta decay (DBD-0ν) is a powerful tool to establish the correct neutrino mass hierarchy and whether the neutrino is a Majorana or Dirac particle. The Milano group has run several experiments using thermal detectors to search for the 130Te DBD-0ν. The Cuoricino experiment consists of an array of 62 TeO 2 thermal detectors for a total mass of about 40 kg, by far the largest cryogenic experiment in the world. The detector installation in the Gran Sasso Underground Laboratory has been recently completed. After a test phase the experiment is now taking data and wemore » report here the preliminary results. In conclusion, Cuoricino is the first step toward the CUORE experiment, which will consists of 1000 TeO 2 thermal detectors for a total mass of about 760 kg: in this paper we discuss also the physics potential of both stages for what concerns the DBD-0ν search. PACS: 11.30.Fs Lepton number – 14.60.Pq Neutrino mass and mixing – 23.40.Bw Weak interactions in beta decay« less

The Geoengineering Model Intercomparison Project Phase 6 (GeoMIP6): Simulation design and preliminary results

DOE PAGES

Kravitz, Benjamin S.; Robock, Alan; Tilmes, S.; ...

2015-10-27

We present a suite of new climate model experiment designs for the Geoengineering Model Intercomparison Project (GeoMIP). This set of experiments, named GeoMIP6 (to be consistent with the Coupled Model Intercomparison Project Phase 6), builds on the previous GeoMIP project simulations, and has been expanded to address several further important topics, including key uncertainties in extreme events, the use of geoengineering as part of a portfolio of responses to climate change, and the relatively new idea of cirrus cloud thinning to allow more long wave radiation to escape to space. We discuss experiment designs, as well as the rationale formore » those designs, showing preliminary results from individual models when available. We also introduce a new feature, called the GeoMIP Testbed, which provides a platform for simulations that will be performed with a few models and subsequently assessed to determine whether the proposed experiment designs will be adopted as core (Tier 1) GeoMIP experiments. In conclusion, this is meant to encourage various stakeholders to propose new targeted experiments that address their key open science questions, with the goal of making GeoMIP more relevant to a broader set of communities.« less

A preliminary investigation of the environmental Control and Life Support Subsystems (EC/LSS) for animal and plant experiment payloads

NASA Technical Reports Server (NTRS)

Wells, H. B.

1972-01-01

A preliminary study of the environmental control and life support subsystems (EC/LSS) necessary for an earth orbital spacecraft to conduct biological experiments is presented. The primary spacecraft models available for conducting these biological experiments are the space shuttle and modular space station. The experiments would be housed in a separate module that would be contained in either the shuttle payload bay or attached to the modular space station. This module would be manned only for experiment-related tasks, and would contain a separate EC/LSS for the crew and animals. Metabolic data were tabulated on various animals that are considered useful for a typical experiment program. The minimum payload for the 30-day space shuttle module was found to require about the equivalent of a one-man EC/LSS; however, the selected two-man shuttle assemblies will give a growth and contingency factor of about 50 percent. The maximum payloads for the space station mission will require at least a seven-man EC/LSS for the laboratory colony and a nine-man EC/LSS for the centrifuge colony. There is practically no room for growth or contingencies in these areas.

Three Dimensional Primary Hepatocyte Culture

NASA Technical Reports Server (NTRS)

Yoffe, Boris

1998-01-01

Our results demonstrated for the first time the feasibility of culturing PHH in microgravity bioreactors that exceeded the longest period obtained using other methods. Within the first week of culture, isolated hepatocytes started to form aggregates, which continuously increased in size (up to 1 cm) and macroscopically appeared as a multidimensional tissue-like assembly. To improve oxygenation and nutrition within the spheroids we performed experiments with the biodegradable nonwoven fiber-based polymers made from PolyGlycolic Acid (PGA). It has been shown that PGA scaffolds stimulate isolated cells to regenerate tissue with defined sizes and shapes and are currently being studied for various tissue-engineering applications. Our data demonstrated that culturing hepatocytes in the presence of PGA scaffolds resulted in more efficient cell assembly and formations of larger cell spheroids (up to 3 cm in length, see figure). The histology of cell aggregates cultured with PGA showed polymer fibers with attached hepatocytes. We initiated experiments to co-culture primary human hepatocytes with human microvascular endothelial cells in the bioreactor. The presence of endothelial cells in co-cultures were established by immunohistochemistry using anti-CD34 monoclonal Ab. Our preliminary data demonstrated that cultures of purified hepatocytes with human microvascular endothelial cells exhibited better growth and expressed higher levels of albumin MRNA for a longer period of time than cultures of ppfified, primary human hepatocytes cultured alone. We also evaluated microsomal deethylation activity of hepatocytes cultured in the presence of endothelial cells.In summary, we have established liver cell culture, which mimicked the structure and function of the parent tissue.

Neuronal responses to vector-averaged gravity: a search for gravisensing and adaptation mechanisms--a preliminary report.

PubMed

Gruener, R

1998-01-01

This paper serves as a milepost in our work using the clinostat as a tool for mimicking certain aspects of altered gravity conditions (vector-nulled gravity) in order to gain insights into the adaptation of cells (and hence organisms) to the microgravity environment of space. I review here recent data, limited to cellular adaptation to altered gravity environments, from others in the field, and including some of our work using the clinostat and from spaceflight experiments. Finally, I report here preliminary results of experiments, carried out initially at Nagoya University's RIEM with follow-up experiments at the University of Arizona, to test the applicability of PC12 cells as neuronal models in which to assess adaptation to altered gravity conditions. PC12 (phaeochromocytoma) cells were used to examine two central hypotheses. The first is that the ubiquity of the cytoskeletally tethered nucleus of cells serves as a general gravisensing device which may be incidental to its other, more central genomic control-role. The second hypothesis is that the clinostat is a useful, earthbound platform on which to carry out space-biology relevant experiments in preparation for testing in space flights. PC12 cells were triggered to differentiate, into neuron-like cells, by the addition of Nerve Growth Factor (NGF) to the culture medium within 4-6 hours after cell plating and just before mounting cultures on the clinostat and control devices. Cultures, in 60 mm or 35 mm polylysine-coated dishes, were subjected to clinorotation, centrifugal force, motional controls and shear-turbulence control conditions for varying periods. Experiments were carried out at 37 degrees C. Cell morphology (including neurite characteristics) and gene activation were examined. Cytoskeletal integrity was assessed from the staining of tubulin and actin filaments. Confocal microscopy in combination with fluorescence monitoring was undertaken. At this point of the investigation, only preliminary data can be presented. This is due to various technical problems and the need to carry out rigorous statistical tests. Still, the preliminary data are of interest because they form the foundation for interpretation against the background of cellular gravisensing and adaptation to gravitational perturbations.

Partial hyperbolicity and attracting regions in 3-dimensional manifolds

NASA Astrophysics Data System (ADS)

Potrie, Rafael

The need for reliable, fiber-based sources of entangled and paired photons has intensified in recent years because of potential uses in optical quantum communication and computing. In particular, indistinguishable photon sources are an inherent part of several quantum communication protocols and are needed to establish the viability of quantum communication networks. This thesis is centered around the development of such sources at telecommunication-band wavelengths. In this thesis, we describe experiments on entangled photon generation and the creation of quantum logic gates in the C-band, and on photon indistinguishability in the O-band. These experiments utilize the four-wave mixing process in fiber which occurs as a result of the Kerr nonlinearity, to create paired photons. To begin, we report the development of a source of 1550-nm polarization entangled photons in fiber. We then interface this source with a quantum Controlled-NOT gate, which is a universal quantum logic gate. We set experimental bounds on the process fidelity of the Controlled-NOT gate. Next, we report a demonstration of quantum interference between 1310-nm photons produced in independent sources. We demonstrate high quantum interference visibility, a signature of quantum indistinguishability, while using distinguishable pump photons. Together, these efforts constitute preliminary steps toward establishing the viability of fiber-based quantum communication, which will allow us to utilize existing infrastructure for implementing quantum communication protocols.

Diffuse optical tomography and spectroscopy of breast cancer and fetal brain

NASA Astrophysics Data System (ADS)

Choe, Regine

Diffuse optical techniques utilize light in the near infrared spectral range to measure tissue physiology non-invasively. Based on these measurements, either on average or a three-dimensional spatial map of tissue properties such as total hemoglobin concentration, blood oxygen saturation and scattering can be obtained using model-based reconstruction algorithms. In this thesis, diffuse optical techniques were applied for in vivo breast cancer imaging and trans-abdominal fetal brain oxygenation monitoring. For in vivo breast cancer imaging, clinical diffuse optical tomography and related instrumentation was developed and used in several contexts. Bulk physiological properties were quantified for fifty-two healthy subjects in the parallel-plate transmission geometry. Three-dimensional images of breast were reconstructed for subjects with breast tumors and, tumor contrast with respect to normal tissue was found in total hemoglobin concentration and scattering and was quantified for twenty-two breast carcinomas. Tumor contrast and tumor volume changes during neoadjuvant chemotherapy were tracked for one subject and compared to the dynamic contrast-enhanced MRI. Finally, the feasibility for measuring blood flow of breast tumors using optical methods was demonstrated for seven subjects. In a qualitatively different set of experiments, the feasibility for trans-abdominal fetal brain oxygenation monitoring was demonstrated on pregnant ewes with induced fetal hypoxia. Preliminary clinical experiences were discussed to identify future directions. In total, this research has translated diffuse optical tomography techniques into clinical research environment.

Direct-Drive Gas-Cooled Reactor Power System: Concept and Preliminary Testing

NASA Technical Reports Server (NTRS)

Wright, S. A.; Lipinski, R. J.; Godfroy, T. J.; Bragg-Sitton, S. M.; VanDyke, M. K.

2002-01-01

This paper describes the concept and preliminary component testing of a gas-cooled, UN-fueled, pin-type reactor which uses He/Xe gas that goes directly into a recuperated Brayton system to produce electricity for nuclear electric propulsion. This Direct-Drive Gas-Cooled Reactor (DDG) is designed to be subcritical under water or wet- sand immersion in case of a launch accident. Because the gas-cooled reactor can directly drive the Brayton turbomachinery, it is possible to configure the system such that there are no external surfaces or pressure boundaries that are refractory metal, even though the gas delivered to the turbine is 1144 K. The He/Xe gas mixture is a good heat transport medium when flowing, and a good insulator when stagnant. Judicious use of stagnant cavities as insulating regions allows transport of the 1144-K gas while keeping all external surfaces below 900 K. At this temperature super-alloys (Hastelloy or Inconel) can be used instead of refractory metals. Super-alloys reduce the technology risk because they are easier to fabricate than refractory metals, we have a much more extensive knowledge base on their characteristics, and, because they have a greater resistance to oxidation, system testing is eased. The system is also relatively simple in its design: no additional coolant pumps, heat exchanger, or freeze-thaw systems are required. Key to success of this concept is a good knowledge of the heat transfer between the fuel pins and the gas, as well as the pressure drop through the system. This paper describes preliminary testing to obtain this key information, as well as experience in demonstrating electrically heated testing of simulated reactor components.

Feasibility and preliminary effects of resistance training and nutritional supplements during versus after radiotherapy in patients with head and neck cancer: A pilot randomized trial.

PubMed

Sandmael, Jon Arne; Bye, Asta; Solheim, Tora Skeidsvoll; Stene, Guro Birgitte; Thorsen, Lene; Kaasa, Stein; Lund, Jo-Åsmund; Oldervoll, Line Merethe

2017-11-15

Patients with head and neck cancer (HNC) experience involuntary weight loss that has a negative impact on physical function, morbidity, and survival. The objective of the current study was to evaluate the feasibility of an exercise and nutrition intervention during radiotherapy (RT) compared with after RT, and to examine preliminary effects on skeletal muscle mass. Patients with HNC were randomized to an exercise and nutrition intervention during RT (EN-DUR) or after RT (EN-AF). The EN-DUR intervention was conducted at a hospital and the EN-AF intervention took place at a rehabilitation center. The interventions consisted of progressive resistance training (PRT) and oral nutritional supplements (ONS). Feasibility outcomes were tracked weekly and muscle mass was measured by computed tomography scans before and after RT and at 2 months follow-up. Of the 50 eligible patients, 41 (82%) agreed to participate. 90% of patients completed the EN-DUR intervention and the adherence to PRT and ONS was 81% and 57%, respectively. 52% of patients attended the EN-AF intervention and adherence to PRT and ONS was 94% and 76%, respectively. The EN-DUR demonstrated a trend toward mitigating loss of muscle mass during RT and the EN-AF demonstrated a similar trend after RT. No difference in muscle mass was detected between the groups from baseline to week 14. An exercise and nutrition intervention is feasible for patients with HNC during RT, and the intervention is potentially effective in mitigating loss of muscle mass both during and after RT. Future trials should assess the feasibility and effects of extended interventions during and after treatment. Cancer 2017;123:4440-8. © 2017 American Cancer Society. © 2017 American Cancer Society.

DEMONSTRATION OF A LIQUID CARBON DIOXIDE PROCESS FOR CLEANING METAL PARTS

EPA Science Inventory

The report gives results of a demonstration of liquid carbon dioxide (LCO2) as an alternative to chlorinated solvents for cleaning metal parts. It describes the LCO2 process, the parts tested, the contaminants removed, and results from preliminary laboratory testing and on-site d...

Hydrocortisone effect on hyaluronate synthesis in a self-assembled human dermal equivalent.

PubMed

Deshpande, Madhura; Papp, Suzanne; Schaffer, Lana; Pouyani, Tara

2016-10-01

Human dermal matrix is a 'self-assembled' dermal equivalent containing large amounts of the glycosaminoglycan hyaluronic acid (hyaluronate, hyaluronan, HA). We sought to investigate the actions of the hormone hydrocortisone on hyaluronate synthesis in the human dermal matrix. To this end, human dermal fibroblasts were cultured under serum-free conditions, and in the absence of a three-dimensional matrix, in the presence of varying amounts of hydrocortisone. The resultant human dermal matrices were characterized. We report that low concentrations of hydrocortisone enhance hyaluronate synthesis in the human dermal equivalent and higher concentrations cause inhibition of hyaluronate synthesis. Other glycosaminoglycan (chondroitin sulphate) synthesis is not affected by changing hydrocortisone concentrations up to 500× (200 µg/ml) of the base value. In order to gain preliminary insight into the molecular mechanism of hyaluronate inhibition, a differential gene array analysis was conducted of human dermal matrix grown in the presence of 200 µg/ml hydrocortisone and in a physiological concentration (0.4 µg/ml, normal conditions). The results of these experiments demonstrate the differential expression of 43 genes in the 500× (200 µg/ml) hydrocortisone construct as compared to the construct grown under normal conditions (0.4 µg/ml hydrocortisone). These preliminary experiments suggest that hydrocortisone at higher concentrations may exert its inhibitory effect on hyaluronate synthesis early in the glycolytic pathway, leading to HA biosynthesis by downregulation of phosphoglucomutase and glucose phosphate isomerase, possibly leading to depletion of the cellular pool of UDP-sugar precursors necessary for HA synthesis. Copyright © 2013 John Wiley & Sons, Ltd. Copyright © 2013 John Wiley & Sons, Ltd.

Small-Interfering RNA–Eluting Surfaces as a Novel Concept for Intravascular Local Gene Silencing

PubMed Central

Nolte, Andrea; Walker, Tobias; Schneider, Martina; Kray, Oya; Avci-Adali, Meltem; Ziemer, Gerhard; Wendel, Hans Peter

2011-01-01

New drug-eluting stent (DES) methods have recently been demonstrated to improve outcomes of intravascular interventions. A novel technique is the design of gene-silencing stents that elute specific small-interfering RNAs (siRNAs) for better vascular wall regeneration. Although siRNAs used to alter gene expression have surpassed expectations in in vitro experiments, the functional and local delivery of siRNAs is still the major obstacle for the in vivo application of RNA interference. In this preliminary in vitro study we investigated a surface-immobilized siRNA delivery technique that would be readily adaptable for local intravascular applications in vivo. The transfection potency of gelatin coatings consisting of a specific siRNA complexed with polyethylenimine (PEI) was examined in primary human endothelial cells by flow cytometry and quantitative real-time polymerase chain reaction. Several media conditions, such as the presence or absence of serum during cultivation, were investigated. Furthermore, different siRNA and PEI amounts, as well as nitrogen/phosphate ratios, were tested for their transfection efficiency. Gelatin coatings consisting of PEI and siRNA against an exemplary endothelial adhesion molecule receptor achieved a significant knockdown of around 70%. The transfection efficiency of the coatings was not influenced by the presence of serum. The results of this preliminary study support the expectation that this novel coating may be favorable for local in vivo gene silencing (for example, when immobilized on stents or balloons for percutanous transluminal coronary angioplasty). However, further animal experiments are needed to confirm the translation into clinical practice. This intriguing technology leads the way to more sophisticated and individualized coatings for the post-DES era, toward silencing of genes involved in the pathway of intimal hyperplasia. PMID:21792480

A Nonlinear Dynamics-Based Estimator for Functional Electrical Stimulation: Preliminary Results From Lower-Leg Extension Experiments.

PubMed

Allen, Marcus; Zhong, Qiang; Kirsch, Nicholas; Dani, Ashwin; Clark, William W; Sharma, Nitin

2017-12-01

Miniature inertial measurement units (IMUs) are wearable sensors that measure limb segment or joint angles during dynamic movements. However, IMUs are generally prone to drift, external magnetic interference, and measurement noise. This paper presents a new class of nonlinear state estimation technique called state-dependent coefficient (SDC) estimation to accurately predict joint angles from IMU measurements. The SDC estimation method uses limb dynamics, instead of limb kinematics, to estimate the limb state. Importantly, the nonlinear limb dynamic model is formulated into state-dependent matrices that facilitate the estimator design without performing a Jacobian linearization. The estimation method is experimentally demonstrated to predict knee joint angle measurements during functional electrical stimulation of the quadriceps muscle. The nonlinear knee musculoskeletal model was identified through a series of experiments. The SDC estimator was then compared with an extended kalman filter (EKF), which uses a Jacobian linearization and a rotation matrix method, which uses a kinematic model instead of the dynamic model. Each estimator's performance was evaluated against the true value of the joint angle, which was measured through a rotary encoder. The experimental results showed that the SDC estimator, the rotation matrix method, and EKF had root mean square errors of 2.70°, 2.86°, and 4.42°, respectively. Our preliminary experimental results show the new estimator's advantage over the EKF method but a slight advantage over the rotation matrix method. However, the information from the dynamic model allows the SDC method to use only one IMU to measure the knee angle compared with the rotation matrix method that uses two IMUs to estimate the angle.

Synthesis of Ti Oxides at Reducing Conditions: Implications for Beamline Standards and Cosmochemistry

NASA Technical Reports Server (NTRS)

Righter, K.; Pando, K. A.; Butterworth, A. L.; Gainsforth, Z.; Jilly-Rehak, C. E.; Westphal, A. J.

2017-01-01

These initial experiments demonstrate the great potential for synthesizing customized compounds for use as standards, or in buffering experiments at reducing conditions. We are also investigating Cr and V oxides, as well as compounds containing these elements such as FeV2O4 and FeCr2O4. Oxygen fugacity exerts a major control on mineral major element chemistry and elemental valence of minerals in any plane-tary compositional system [1]. For Earth, Fe is multivalent ranging from nearly Fe0 at low fO2 in the deep mantle to Fe2+ to Fe3+ at high low fO2. For solar nebular and meteoritic materials fO2 ranges from near IW to 10 log fO2 units below the IW buffer [1]. Phases in CAIs, for example, contain no Fe2+, but may contain Ti4+, Ti3+, or Ti2+, and Cr3+ or Cr2+, and V3+ or V2+ [1,2,3]. De-tailed study of inclusions may reveal important differences in fO2 thus reflecting different environments in the solar nebula [4]. XANES, FEG-SEM, and TEM can reveal such variations in micro and nano samples such as Stardust and cosmic dust particles [5], but successful application to reduced conditions depends upon the availability of well characterized standards. Acquiring appropriate standards for reduced phases that contain Ti3+ or Ti2+, Cr3+ or Cr2+, and V3+ or V2+ can be a challenge. Here we report our preliminary results at synthesizing reduced Ti bearing standards, and focus on the preliminary characterization.

Preliminary measurements of 135Cs with AMS

NASA Astrophysics Data System (ADS)

Yin, Xinyi; He, Ming; Dong, Kejun; Dou, Liang; Lan, Xiaoxi; Pang, Fangfang; Wu, Shaoyong; Jiang, Shan

2015-10-01

135Cs is an interesting nuclide in many research fields, especially in environmental study. Preliminary measurements of the long-lived 135Cs with accelerator mass spectrometry (AMS) have been developed with the HI-13 tandem AMS facility at China Institute of Atomic Energy (CIAE). In order to improve ion extracting current and depressing background interference, experiments were carried out on different ions of Cs extracted from different samples. It was found that Cs- extracted from CsNO3 can be used for AMS measurement of 135Cs. According to the preliminary results, the background level can be obtained with blanks was 135Ba/Cs ∼ 8.8 × 10-12 with the CIAE-AMS system.

Final definition and preliminary design study for the initial atmospheric cloud physics laboratory, a Spacelab mission payload

NASA Technical Reports Server (NTRS)

1976-01-01

The following areas related to the final definition and preliminary design study of the initial atmospheric cloud physics laboratory (ACPL) were covered: (1) proposal organization, personnel, schedule, and project management, (2) proposed configurations, (3) study objectives, (4) ACPL experiment program listing and description, (5) mission/flight flexibility and modularity/commonality, (6) study plan, and (7) description of following tasks: requirement analysis and definition task flow, systems analysis and trade studies, subsystem analysis and trade studies, specifications and interface control documents, preliminary design task flow, work breakdown structure, programmatic analysis and planning, and project costs. Finally, an overview of the scientific requirements was presented.

A Paired-Associates Analysis of Reading Acquisition.

ERIC Educational Resources Information Center

Muller, Douglas G.

A major objective of this study was to seek the relationship of principles derived from traditional paired-associates transfer experiments as applied to the reading task. In this experiment 10 subjects from upper-division education courses, all volunteers, received various types of preliminary training with letter stimuli; then all subjects…

Chemical pump study

NASA Technical Reports Server (NTRS)

Bergquist, L. E.

1973-01-01

Sorption pumps applicable to the Pioneer Venus Mass Spectrometer Experiment were investigated. The pump requirements are discussed, and a survey of the existing pumps presented. Zirconium and zirconium graphite products were found to be the most promising among the getter materials surveyed. A preliminary pump design for the noble gas experiment is discussed.

Preliminary experience with a stereoscopic video system in a remotely piloted aircraft application

NASA Technical Reports Server (NTRS)

Rezek, T. W.

1983-01-01

Remote piloting video display development at the Dryden Flight Research Facility of NASA's Ames Research Center is summarized, and the reasons for considering stereo television are presented. Pertinent equipment is described. Limited flight experience is also discussed, along with recommendations for further study.

The Glacier Lakes Ecosystem Experiments Site

Treesearch

R. C. Musselman

1994-01-01

The Glacier Lakes Ecosystem Experiment Site (GLEES), a 600 ha research watershed at 3200-3400 m elevation in the Snowy Range of SE Wyoming, has been established to examine the effects of atmospheric deposition on alpine and subalpine ecosystems. This document provides preliminary data on the landscape habitats, floristics, geology, soils, aquatics, atmospheric...

Child Peer Sexual Abuse: Preliminary Data on Outcomes and Disclosure Experiences

ERIC Educational Resources Information Center

Sperry, Debbie M.; Gilbert, Brenda O.

2005-01-01

Objective: This study compared experiences of children sexually abused by peers to those of children abused by adolescents/adults. Variables examined included perceived negativity of the abuse, self-reported outcomes, overall psychological functioning, and disclosure. Method: An archival data set containing retrospective reports of childhood…

FABS (Formulated Abstracting): An Experiment in Regularized Content Description.

ERIC Educational Resources Information Center

Harris, Brian; Hofmann, Thomas R.

This preliminary report of research conducted at the Linguistics Documentation Centre of the University of Ottawa describes a bilingual experiment into the elaboration of well structured formulary routines for making the writing of abstracts easier, and at the same time standardizing and generally augmenting the information given in them. The…

LDEF: 69 Months in Space. First Post-Retrieval Symposium, part 2

NASA Technical Reports Server (NTRS)

Levine, Arlene S. (Editor)

1992-01-01

A compilation of papers from the symposium is presented. The preliminary data analysis is presented of the 57 experiments flown on the LDEF. The experiments include materials, coatings, thermal systems, power and propulsion, science (cosmic ray, interstellar gas, heavy ions, and micrometeoroid), electronics, optics, and life science.

Regulation of pumping function of the heart in developing body under changing regimens of motor activity.

PubMed

Vafina, E Z; Abzalov, R A; Abzalov, N I; Nikitin, A S; Gulyakov, A A

2014-06-01

We analyzed parameters of the pumping function of the heart in rats subjected to enhanced motor activity after a preliminary 70-day hypokinesia under conditions of α- and β-adrenergic receptor stimulation with norepinephrine followed by blockade of β-adrenergic receptor with propranolol (obsidian) and α1-adrenergic receptors with doxazosin. After norepinephrine administration, the HR and cardiac output were higher in rats with enhanced physical activity after preliminary hypokinesia than in rats with low physical activity. After propranolol administration, stroke volume and cardiac output in 100-day-old rats with limited activity were lower, and HR higher was than in rats with enhanced physical activity after preliminary 70-day hypokinesia. After administration of doxazosin, rats with limited motor activity demonstrated more pronounced changes in HR than rats with enhanced physical activity after preliminary 70-day hypokinesia.

A Module Experimental Process System Development Unit (MEPSDU)

NASA Technical Reports Server (NTRS)

1981-01-01

The purpose of this program is to demonstrate the technical readiness of a cost effective process sequence that has the potential for the production of flat plate photovoltaic modules which met the price goal in 1986 of $.70 or less per watt peak. Program efforts included: preliminary design review, preliminary cell fabrication using the proposed process sequence, verification of sandblasting back cleanup, study of resist parameters, evaluation of pull strength of the proposed metallization, measurement of contact resistance of Electroless Ni contacts, optimization of process parameter, design of the MEPSDU module, identification and testing of insulator tapes, development of a lamination process sequence, identification, discussions, demonstrations and visits with candidate equipment vendors, evaluation of proposals for tabbing and stringing machine.

Preliminary Geologic/spectral Analysis of LANDSAT-4 Thematic Mapper Data, Wind River/bighorn Basin Area, Wyoming

NASA Technical Reports Server (NTRS)

Lang, H. R.; Conel, J. E.; Paylor, E. D.

1984-01-01

A LIDQA evaluation for geologic applications of a LANDSAT TM scene covering the Wind River/Bighorn Basin area, Wyoming, is examined. This involves a quantitative assessment of data quality including spatial and spectral characteristics. Analysis is concentrated on the 6 visible, near infrared, and short wavelength infrared bands. Preliminary analysis demonstrates that: (1) principal component images derived from the correlation matrix provide the most useful geologic information. To extract surface spectral reflectance, the TM radiance data must be calibrated. Scatterplots demonstrate that TM data can be calibrated and sensor response is essentially linear. Low instrumental offset and gain settings result in spectral data that do not utilize the full dynamic range of the TM system.

Intelligent redundant actuation system requirements and preliminary system design

NASA Technical Reports Server (NTRS)

Defeo, P.; Geiger, L. J.; Harris, J.

1985-01-01

Several redundant actuation system configurations were designed and demonstrated to satisfy the stringent operational requirements of advanced flight control systems. However, this has been accomplished largely through brute force hardware redundancy, resulting in significantly increased computational requirements on the flight control computers which perform the failure analysis and reconfiguration management. Modern technology now provides powerful, low-cost microprocessors which are effective in performing failure isolation and configuration management at the local actuator level. One such concept, called an Intelligent Redundant Actuation System (IRAS), significantly reduces the flight control computer requirements and performs the local tasks more comprehensively than previously feasible. The requirements and preliminary design of an experimental laboratory system capable of demonstrating the concept and sufficiently flexible to explore a variety of configurations are discussed.

Sanford Underground Research Facility - The United State's Deep Underground Research Facility

NASA Astrophysics Data System (ADS)

Vardiman, D.

2012-12-01

The 2.5 km deep Sanford Underground Research Facility (SURF) is managed by the South Dakota Science and Technology Authority (SDSTA) at the former Homestake Mine site in Lead, South Dakota. The US Department of Energy currently supports the development of the facility using a phased approach for underground deployment of experiments as they obtain an advanced design stage. The geology of the Sanford Laboratory site has been studied during the 125 years of operations at the Homestake Mine and more recently as part of the preliminary geotechnical site investigations for the NSF's Deep Underground Science and Engineering Laboratory project. The overall geology at DUSEL is a well-defined stratigraphic sequence of schist and phyllites. The three major Proterozoic units encountered in the underground consist of interbedded schist, metasediments, and amphibolite schist which are crosscut by Tertiary rhyolite dikes. Preliminary geotechnical site investigations included drift mapping, borehole drilling, borehole televiewing, in-situ stress analysis, laboratory analysis of core, mapping and laser scanning of new excavations, modeling and analysis of all geotechnical information. The investigation was focused upon the determination if the proposed site rock mass could support the world's largest (66 meter diameter) deep underground excavation. While the DUSEL project has subsequently been significantly modified, these data are still available to provide a baseline of the ground conditions which may be judiciously extrapolated throughout the entire Proterozoic rock assemblage for future excavations. Recommendations for facility instrumentation and monitoring were included in the preliminary design of the DUSEL project design and include; single and multiple point extensometers, tape extensometers and convergence measurements (pins), load cells and pressure cells, smart cables, inclinometers/Tiltmeters, Piezometers, thermistors, seismographs and accelerometers, scanners (laser/LIDAR), surveying instruments, and surveying benchmarks and optical survey points. Currently an array of single and multipoint extensometers monitors the Davis Campus. A facility-wide micro seismic monitoring system is anticipated to be deployed during the latter half of 2012. This system is designed to monitor minor events initiated within the historical mined out portions of the facility. The major science programs for the coming five years consist of the MAJORANA DEMONSTRATOR (MJD) neutrinoless double beta decay experiment; the Large Underground Xenon (LUX) dark matter search, the Center for Ultralow Background Experiments at DUSEL (CUBED), numerous geoscience installations, Long-Baseline Neutrino Experiment (LBNE), a nuclear astrophysics program involving a low energy underground particle accelerator, second and third generation dark matter experiments, and additional low background counting facilities. The Sanford Lab facility is an active, U.S. based, deep underground research facility dedicated to science, affording the science community the opportunity to conduct unprecedented scientific research in a broad range of physics, biology and geoscience fields at depth. SURF is actively interested in hosting additional research collaborations and provides resources for full facility design, cost estimation, excavation, construction and support management services.

Application of Pi Preform Composite Joints in Fabrication of NASA Composite Crew Module Demonstration Structure

NASA Technical Reports Server (NTRS)

Higgins, John E.; Pelham, Larry

2008-01-01

This paper will describe unique and extensive use of pre-woven and impregnated pi cross-sections in fabrication of a carbon composite demonstration structure for the Composite Crew Module (CCM) Program. The program is managed by the NASA Safety and Engineering Center with participants from ten NASA Centers and AFRL. Multiple aerospace contractors are participating in the design development, tooling and fabrication effort as well. The goal of the program is to develop an agency wide design team for composite habitable spacecraft. The specific goals for this development project are: a) To gain hands on experience in design, building and testing a composite crew module. b) To validate key assumptions by resolving composite spacecraft design details through fabrication and testing of hardware. This paper will focus on the design and fabrication issues supporting selection of the Lockheed Martin patented Pi pre-form to provide sound composite joints a numerous locations in the structure. This abstract is based on Preliminary Design data. The final design will continue to evolve through the fall of 2007 with fabrication mostly completed by conference date.

A preliminary 6-month prospective study examining self-reported religious preference, religiosity/spirituality, and retention at a Jewish residential treatment center for substance-related disorders.

PubMed

Parhami, Iman; Davtian, Margarit; Collard, Michael; Lopez, Jean; Fong, Timothy W

2014-07-01

Although there is a substantial amount of research suggesting that higher levels of religiosity/spirituality (R/S) are associated with better treatment outcomes of substance-related disorders, no studies have explored this relationship at a faith-based residential treatment center. The objective of this prospective study is to explore the relationship between R/S, self-reported religious preference, and retention at a Jewish residential treatment center for substance-related disorders. Using the Daily Spiritual Experience Scale, R/S levels were assessed for 33 subjects at baseline, 1 month, 3 months, and 6 months. Results demonstrated a significant relationship between baseline R/S level and retention at 6 months, while R/S levels were unchanged during the course of treatment. Notably, no relationship was found between self-reported religious affiliation and retention. This study demonstrates that patients' R/S level, rather than religious affiliation, is a possible predictor for better outcome at faith-based residential centers for substance-related disorders.

Investigation of the enzymology and pharmacology of novel substrates and inhibitors of dopamine beta-monooxygenase

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roberts, S.F.

1987-01-01

Dopamine beta-monooxygenase (DBM) was shown to catalyze the selenoxidation of 2-(phenylseleno)ethylamines, selenium-containing analogues of dopamine, by the normal monooxygenase pathway. The compounds 2-(phenylseleno)-ethylamine (PAESe), 2-(4'-hydroxyphenylseleno)ethylamine (pOH PAESe), and 1-(phenylseleno)-2-propylamine (Me PAESe) were synthesized and fully characterized as DBM substrates. Two other classes of compounds were investigated as potential alternate substrates for DBM. The possibility of stereoselective sulfonylation of 2-(phenylsulfenyl)- ethylamine (PAESO) was considered. A unique class of compounds, 2-(phenylthio)ethanols were designed and synthesized as DBM substrates but were found to be a novel class of potent competitive inhibitors of DBM with respect to tyramine. Preliminary experiments were also performed inmore » an effort to demonstrate that the potent antihypertensive and indirect-acting sympathomimetic activity of 2-(phenylthio)ethylamine (PAES) was a result of DBM-oxygenation of this compound in vivo. The specific reserpine-sensitive uptake of (/sup 3/H)-norepinephrine into rat brain synaptosomes was demonstrated as was the synaptosomal conversion of (/sup 3/H)-dopamine to (/sup 3/H)-norepinephrine.« less

A Preliminary 6-Month Prospective Study Examining Self-reported Religious Preference, Religiosity/Spirituality, and Retention at a Jewish Residential Treatment Center for Substance-Related Disorders

PubMed Central

Davtian, Margarit; Collard, Michael; Lopez, Jean; Fong, Timothy W.

2012-01-01

Although there is a substantial amount of research suggesting that higher levels of religiosity/spirituality (R/S) are associated with better treatment outcomes of substance-related disorders, no studies have explored this relationship at a faith-based residential treatment center. The objective of this prospective study is to explore the relationship between R/S, self-reported religious preference, and retention at a Jewish residential treatment center for substance-related disorders. Using the Daily Spiritual Experience Scale, R/S levels were assessed for 33 subjects at baseline, 1 month, 3 months, and 6 months. Results demonstrated a significant relationship between baseline R/S level and retention at 6 months, while R/S levels were unchanged during the course of treatment. Notably, no relationship was found between self-reported religious affiliation and retention. This study demonstrates that patients’ R/S level, rather than religious affiliation, is a possible predictor for better outcome at faith-based residential centers for substance-related disorders. PMID:22460083

AgRISTARS. Preliminary technical results review of FY81 experiments, volume 2: Fiscal year 1981/1982 "corn and soybeans pilot" experiment

NASA Technical Reports Server (NTRS)

1981-01-01

The performance of the technology exhibited significant proportion estimation errors, specifically, high mean error in both corn and soybeans area estimation. The data systems, technical approaches, and data assessment of the pilot experiment were reviewed. Results of proportion estimations procedure performance evaluations, and sensitivity evaluations are presented. The role of the pilot experiment in foreign technology development is discussed.

The application of 3D image processing to studies of the musculoskeletal system

NASA Astrophysics Data System (ADS)

Hirsch, Bruce Elliot; Udupa, Jayaram K.; Siegler, Sorin; Winkelstein, Beth A.

2009-10-01

Three dimensional renditions of anatomical structures are commonly used to improve visualization, surgical planning, and patient education. However, such 3D images also contain information which is not readily apparent, and which can be mined to elucidate, for example, such parameters as joint kinematics, spacial relationships, and distortions of those relationships with movement. Here we describe two series of experiments which demonstrate the functional application of 3D imaging. The first concerns the joints of the ankle complex, where the usual description of motions in the talocrural joint is shown to be incomplete, and where the roles of the anterior talofibular and calcaneofibular ligaments are clarified in ankle sprains. Also, the biomechanical effects of two common surgical procedures for repairing torn ligaments were examined. The second series of experiments explores changes in the anatomical relationships between nerve elements and the cervical vertebrae with changes in neck position. They provide preliminary evidence that morphological differences may exist between asymptomatic subjects and patients with radiculopathy in certain positions, even when conventional imaging shows no difference.

Solution and shock-induced exsolution of argon in vitreous carbon

NASA Technical Reports Server (NTRS)

Gazis, Carey; Ahrens, Thomas J.

1991-01-01

To add to the knowledge of noble gas solution and exsolution in carbonaceus material, experiments were performed on vitreous carbon. Ar-rich vitreous carbon samples were prepared under vapor-saturated conditions using argon as the pressurizing medium. Solubility data were obtained for temperatures of 773 to 973 K and pressures of 250 to 1500 bars. Up to 7 wt pct Ar was dissolved in the carbon. The solubility data were compared to a thermodynamic model of argon atoms dissolving into a fixed population of 'holes' in the carbon. Two variations of the model yielded estimates of the enthalpy of solution of Ar in vitreous carbon equal to about -4700 cal/mole. Preliminary shock experiments showed that 28 percent of the total argon was released by driving 4 GPa shocks into the argon-rich carbon. It was demonstrated that shock-induced argon loss is not simply caused by the impact-induced diminution of grain size. The present value of shock pressure required for partial impact devolatilization of Ar from carbon is below the range (5-30 GPa) at which H2O is released from phyllosilicates.

ROTSE All-Sky Surveys for Variable Stars. I. Test Fields

NASA Astrophysics Data System (ADS)

Akerlof, C.; Amrose, S.; Balsano, R.; Bloch, J.; Casperson, D.; Fletcher, S.; Gisler, G.; Hills, J.; Kehoe, R.; Lee, B.; Marshall, S.; McKay, T.; Pawl, A.; Schaefer, J.; Szymanski, J.; Wren, J.

2000-04-01

The Robotic Optical Transient Search Experiment I (ROTSE-I) experiment has generated CCD photometry for the entire northern sky in two epochs nightly since 1998 March. These sky patrol data are a powerful resource for studies of astrophysical transients. As a demonstration project, we present first results of a search for periodic variable stars derived from ROTSE-I observations. Variable identification, period determination, and type classification are conducted via automatic algorithms. In a set of nine ROTSE-I sky patrol fields covering roughly 2000 deg2, we identify 1781 periodic variable stars with mean magnitudes between mv=10.0 and mv=15.5. About 90% of these objects are newly identified as variable. Examples of many familiar types are presented. All classifications for this study have been manually confirmed. The selection criteria for this analysis have been conservatively defined and are known to be biased against some variable classes. This preliminary study includes only 5.6% of the total ROTSE-I sky coverage, suggesting that the full ROTSE-I variable catalog will include more than 32,000 periodic variable stars.

‘I quit’ versus ‘I'm sorry I used’: A preliminary investigation of variations in narrative ending and transportation

PubMed Central

Banerjee, Smita C.; Greene, Kathryn

2016-01-01

A narrative experience can partly depend on how a narrative ends or concludes. This study examined prevention effects of personal drug use narratives varying by type of ending and gender of protagonist. Additionally, the role of transportation in the persuasion process, particularly the association between transportation and cocaine use intentions, both directly and indirectly, through the mediation of antidrug and pro-drug expectancies was assessed. A total of 500 undergraduate students at a large northern university in the UK participated in the experiment which was a 2 × 2 × 2 mixed design with ending (progressive vs. regressive) and gender of protagonist (male vs. female) as within-participants factors and participant gender (male vs. female) as between-participants factors. The results demonstrated significant main effects for ending, gender of protagonist in the narrative and participant gender, but no interaction effects. Finally, greater transportation was associated with stronger anti-cocaine expectancies, which were further associated with lower cocaine use intentions. Important theoretical and empirical implications are discussed. PMID:22519724

A Preliminary Study of CO2 Flux Measurements by Lidar

NASA Technical Reports Server (NTRS)

Gibert, Fabien; Koch, Grady J.; Beyon, Jeffrey Y.; Hilton, T.; Davis, Kenneth J.; Andrews, Arlyn; Ismail, Syed; Singh, Upendra N.

2008-01-01

A mechanistic understanding of the global carbon cycle requires quantification of terrestrial ecosystem CO2 fluxes at regional scales. In this paper, we analyze the potential of a Doppler DIAL system to make flux measurements of atmospheric CO2 using the eddy-covariance and boundary layer budget methods and present results from a ground based experiment. The goal of this study is to put CO2 flux point measurements in a mesoscale context. In June 2007, a field experiment combining a 2-m Doppler Heterodyne Differential Absorption Lidar (HDIAL) and in-situ sensors of a 447-m tall tower (WLEF) took place in Wisconsin. The HDIAL measures simultaneously: 1) CO2 mixing ratio, 2) atmosphere structure via aerosol backscatter and 3) radial velocity. We demonstrate how to synthesize these data into regional flux estimates. Lidar-inferred fluxes are compared with eddy-covariance fluxes obtained in-situ at 396m AGL from the tower. In cases where the lidar was not yet able to measure the fluxes with acceptable precision, we discuss possible modifications to improve system performance.

Progress of the LASL dry hot rock geothermal energy project

NASA Technical Reports Server (NTRS)

Smith, M. C.

1974-01-01

The possibilities and problems of extracting energy from geothermal reservoirs which do not spontaneously yield useful amounts of steam or hot water are discussed. The system for accomplishing this which is being developed first is a pressurized-water circulation loop intended for use in relatively impermeable hot rock. It will consist of two holes connected through the hot rock by a very large hydraulic fracture and connected at the surface through the primary heat exchanger of an energy utilization system. Preliminary experiments in a hole 2576 ft (0.7852 km) deep, extending about 470 ft (143 m) into the Precambrian basement rock underlying the Jemez Plateau of north-central New Mexico, revealed no unexpected difficulties in drilling or hydraulically fracturing such rock at a temperature of approximately 100 C, and demonstrated a permeability low enough so that it appeared probable that pressurized water could be contained by the basement rock. Similar experiments are in progress in a second hole, now 6701 ft (2.043 km) deep, about 1.5 miles (2.4 km) south of the first one.

Wearable ultrasonic guiding device with white cane for the visually impaired: A preliminary verisimilitude experiment.

PubMed

Cheng, Po-Hsun

2016-01-01

Several assistive technologies are available to help visually impaired individuals avoid obstructions while walking. Unfortunately, white canes and medical walkers are unable to detect obstacles on the road or react to encumbrances located above the waist. In this study, I adopted the cyber-physical system approach in the development of a cap-connected device to compensate for gaps in detection associated with conventional aids for the visually impaired. I developed a verisimilar, experimental route involving the participation of seven individuals with visual impairment, including straight sections, left turns, right turns, curves, and suspended objects. My aim was to facilitate the collection of information required for the practical use of the device. My findings demonstrate the feasibility of the proposed guiding device in alerting walkers to the presence of some kinds of obstacles from the small number of subjects. That is, it shows promise for future work and research with the proposed device. My findings provide a valuable reference for the further improvement of these devices as well as the establishment of experiments involving the visually impaired.

Compact pulsed high-energy Er:glass laser

NASA Astrophysics Data System (ADS)

Wan, Peng; Liu, Jian

2012-03-01

Bulk Erbium-doped lasers are widely used for long-distance telemetry and ranging. In some applications such as coherent Doppler radars, laser outputs with a relatively long pulse width, good beam profile and pulse shape are required. High energy Q-switched Er:glass lasers were demonstrated by use of electro-optic (E/O) Q-switching or frustrated total internal reflection (FTIR) Q-switching. However, the output pulse durations in these lasers were fixed to relatively small values and extremely hard to tune. We report here on developing a novel and compact Q-switched Er:Yb co-doped phosphate glass laser at an eye-safe wavelength of 1.5 μm. A rotating mirror was used as a Q-switch. Co-linear pump scheme was used to maintain a good output beam profile. Near-perfect Gaussian temporal shape was obtained in our experiment. By changing motor rotation speed, pulse duration was tunable and up to 240 ns was achieved. In our preliminary experiment, output pulse energies of 44 mJ and 4.5 mJ were obtained in free-running and Q-switched operation modes respectively.

Preliminary Experiment of Non-Inductive Plasma Current Startup in SUNIST Spherical Tokamak

NASA Astrophysics Data System (ADS)

He, Yexi; Zhang, Liang; Xie, Lifeng; Tang, Yi; Yang, Xuanzong; Feng, Chunhua; Fu, Hongjun

2006-01-01

The non-inductive plasma current startup is an important motivation in SUNIST spherical tokamak. In the recent experiment, the magnetron microwave system of 100 kW and 2.45 GHz has been used to the ECR plasma current startup. Besides the toroidal field, a vertical field was applied to generate preliminary toroidal plasma current without the action of the central solenoid. As the evidence of plasma current startup with the effect of vertical field drift, the direction of plasma current is changed when the direction of vertical field changes during the ECR plasma current startup discharge. We also observed a maximum plasma current by scanning vertical field in both directions. Additionally, we used electrode discharge to assist the ECR plasma current startup.

Apollo 17 traverse gravimeter experiment /Preliminary results/

NASA Technical Reports Server (NTRS)

Talwani, M.; Kahle, H.-G.

1976-01-01

Preliminary results of the traverse gravimeter experiment successfully performed during the Apollo 17 mission are discussed. An earth-moon gravity tie was established. On the basis of several readings, a gravity value of 162,695 + or - 5 mgal was obtained at the lunar-module landing site in the Taurus-Littrow valley. Free-air and Bouguer corrections were applied to the gravity data. The resultant Bouguer anomaly, analyzed with a two-dimensional approximation, shows a relative gravity maximum of about 25 to 30 mgal over the Taurus-Littrow valley. This maximum is interpreted in terms of a 1-km-thick block of basalt flow with a positive density contrast of 0.8 g/cu cm relative to the highland material on either side.

Preliminary design of laser-induced breakdown spectroscopy for proto-Material Plasma Exposure eXperiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shaw, G., E-mail: shawgc@ornl.gov; University of Tennessee, Knoxville, Tennessee 37996; Martin, M. Z.

2014-11-15

Laser-induced breakdown spectroscopy (LIBS) is a technique for measuring surface matter composition. LIBS is performed by focusing laser radiation onto a target surface, ablating the surface, forming a plasma, and analyzing the light produced. LIBS surface analysis is a possible diagnostic for characterizing plasma-facing materials in ITER. Oak Ridge National Laboratory has enabled the initial installation of a laser-induced breakdown spectroscopy diagnostic on the prototype Material-Plasma Exposure eXperiment (Proto-MPEX), which strives to mimic the conditions found at the surface of the ITER divertor. This paper will discuss the LIBS implementation on Proto-MPEX, preliminary design of the fiber optic LIBS collectionmore » probe, and the expected results.« less

The Thirty Gigahertz Instrument Receiver for the QUIJOTE Experiment: Preliminary Polarization Measurements and Systematic-Error Analysis

PubMed Central

Casas, Francisco J.; Ortiz, David; Villa, Enrique; Cano, Juan L.; Cagigas, Jaime; Pérez, Ana R.; Aja, Beatriz; Terán, J. Vicente; de la Fuente, Luisa; Artal, Eduardo; Hoyland, Roger; Génova-Santos, Ricardo

2015-01-01

This paper presents preliminary polarization measurements and systematic-error characterization of the Thirty Gigahertz Instrument receiver developed for the QUIJOTE experiment. The instrument has been designed to measure the polarization of Cosmic Microwave Background radiation from the sky, obtaining the Q, U, and I Stokes parameters of the incoming signal simultaneously. Two kinds of linearly polarized input signals have been used as excitations in the polarimeter measurement tests in the laboratory; these show consistent results in terms of the Stokes parameters obtained. A measurement-based systematic-error characterization technique has been used in order to determine the possible sources of instrumental errors and to assist in the polarimeter calibration process. PMID:26251906

Toward Scalable Ion Traps for Quantum Information Processing

DTIC Science & Technology

2010-01-01

3/033031 Abstract. In this paper, we report the design, fabrication and preliminary testing of a 150 zone ion trap array built in a ‘ surface ...gates [4–6]. We report here on the design, fabrication and preliminary testing of a large array built in a ‘ surface -electrode’ geometry [7, 8] and...report the first transport of atomic ions through a surface -electrode trap junction. Transport of ions through a junction has been demonstrated previously

Optimization of interplanetary trajectories with unpowered planetary swingbys

NASA Technical Reports Server (NTRS)

Sauer, Carl G., Jr.

1988-01-01

A method is presented for calculating and optimizing unpowered planetary swingby trajectories using a patched conic trajectory generator. Examples of unpowered swingby trajectories are given to demonstrate the method. The method, which uses primer vector theory, is not highly accurate, but provides projections for preliminary mission definition studies. Advantages to using a patched conic trajectory simulation for preliminary studies which examine many different and complex missions include calculation speed and adaptability to changes or additions to the formulation.

Design of Human-Machine Interface and altering of pelvic obliquity with RGR Trainer.

PubMed

Pietrusinski, Maciej; Unluhisarcikli, Ozer; Mavroidis, Constantinos; Cajigas, Iahn; Bonato, Paolo

2011-01-01

The Robotic Gait Rehabilitation (RGR) Trainer targets secondary gait deviations in stroke survivors undergoing rehabilitation. Using an impedance control strategy and a linear electromagnetic actuator, the device generates a force field to control pelvic obliquity through a Human-Machine Interface (i.e. a lower body exoskeleton). Herein we describe the design of the RGR Trainer Human-Machine Interface (HMI) and we demonstrate the system's ability to alter the pattern of movement of the pelvis during gait in a healthy subject. Results are shown for experiments during which we induced hip-hiking - in healthy subjects. Our findings indicate that the RGR Trainer has the ability of affecting pelvic obliquity during gait. Furthermore, we provide preliminary evidence of short-term retention of the modified pelvic obliquity pattern induced by the RGR Trainer. © 2011 IEEE

Region-based multi-step optic disk and cup segmentation from color fundus image

NASA Astrophysics Data System (ADS)

Xiao, Di; Lock, Jane; Manresa, Javier Moreno; Vignarajan, Janardhan; Tay-Kearney, Mei-Ling; Kanagasingam, Yogesan

2013-02-01

Retinal optic cup-disk-ratio (CDR) is a one of important indicators of glaucomatous neuropathy. In this paper, we propose a novel multi-step 4-quadrant thresholding method for optic disk segmentation and a multi-step temporal-nasal segmenting method for optic cup segmentation based on blood vessel inpainted HSL lightness images and green images. The performance of the proposed methods was evaluated on a group of color fundus images and compared with the manual outlining results from two experts. Dice scores of detected disk and cup regions between the auto and manual results were computed and compared. Vertical CDRs were also compared among the three results. The preliminary experiment has demonstrated the robustness of the method for automatic optic disk and cup segmentation and its potential value for clinical application.

Encrypted optical storage with wavelength-key and random phase codes.

PubMed

Matoba, O; Javidi, B

1999-11-10

An encrypted optical memory system that uses a wavelength code as well as input and Fourier-plane random phase codes is proposed. Original data are illuminated by a coherent light source with a specified wavelength and are then encrypted with two random phase codes before being stored holographically in a photorefractive material. Successful decryption requires the use of a readout beam with the same wavelength as that used in the recording, in addition to the correct phase key in the Fourier plane. The wavelength selectivity of the proposed system is evaluated numerically. We show that the number of available wavelength keys depends on the correlation length of the phase key in the Fourier plane. Preliminary experiments of encryption and decryption of optical memory in a LiNbO(3):Fe photorefractive crystal are demonstrated.

Design of compact dispersion interferometer with a high efficiency nonlinear crystal and a low power CO2 laser

NASA Astrophysics Data System (ADS)

Akiyama, T.; Yoshimura, S.; Tomita, K.; Shirai, N.; Murakami, T.; Urabe, K.

2017-12-01

When the electron density of a plasma generated in high pressure environment is measured by a conventional interferometer, the phase shifts due to changes of the neutral gas density cause significant measurement errors. A dispersion interferometer, which measures the phase shift that arises from dispersion of medium between the fundamental and the second harmonic wavelengths of laser light, can suppress the measured phase shift due to the variations of neutral gas density. In recent years, the CO2 laser dispersion interferometer has been applied to the atmospheric pressure plasmas and its feasibility has been demonstrated. By combining a low power laser and a high efficiency nonlinear crystal for the second harmonic component generation, a compact dispersion interferometer can be designed. The optical design and preliminary experiments are conducted.

Large charged drop levitation against gravity

NASA Technical Reports Server (NTRS)

Rhim, Won-Kyu; Chung, Sang Kun; Hyson, Michael T.; Trinh, Eugene H.; Elleman, Daniel D.

1987-01-01

A hybrid electrostatic-acoustic levitator that can levitate and manipulate a large liquid drop in one gravity is presented. To the authors' knowledge, this is the first time such large drops (up to 4 mm in diameter in the case of water) have been levitated against 1-gravity. This makes possible, for the first time, many new experiments both in space and in ground-based laboratories, such as 1)supercooling and superheating, 2) containerless crystal growth from various salt solutions or melts, 3) drop dynamics of oscillating or rotating liquid drops, 4) drop evaporation and Rayleigh bursting, and 5) containerless material processing in space. The digital control system, liquid drop launch process, principles of electrode design, and design of a multipurpose room temperature levitation chamber are described. Preliminary results that demonstrate drop oscillation and rotation, and crystal growth from supersaturated salt solutions are presented.

Cognitions and emotions in eating disorders.

PubMed

Siep, Nicolette; Jansen, Anita; Havermans, Remco; Roefs, Anne

2011-01-01

The cognitive model of eating disorders (EDs) states that the processing of external and internal stimuli might be biased in mental disorders. These biases, or cognitive errors, systematically distort the individual's experiences and, in that way, maintains the eating disorder. This chapter presents an updated literature review of experimental studies investigating these cognitive biases. Results indicate that ED patients show biases in attention, interpretation, and memory when it comes to the processing of food-, weight-, and body shape-related cues. Some recent studies show that they also demonstrate errors in general cognitive abilities such as set shifting, central coherence, and decision making. A future challenge is whether cognitive biases and processes can be manipulated. Few preliminary studies suggest that an attention retraining and training in the cognitive modulation of food reward processing might be effective strategies to change body satisfaction, food cravings, and eating behavior.

[Projective identification, mimesis and the analytical situation. Preliminary observations].

PubMed

Ruberto, A; Lucchi, N; Senesi, P; Gaston, A

1990-01-01

In an attempt to underline the need to refer to an imaginary setting, in which the analytical relationship is acted out, the Authors have considered the possible relations between the concept of projective identification, as defined by Klein and further developed by Bion, and the idea of "Mimesis", which is inevitably involved in every story, and which confronts the imaginary at the very moment in which it is produced. The "fusion" between subject and object, which may occur in a more or less partial manner, is defined as a phenomenal demonstration of the participation of the two poles of the relationship in a "super-individual" experience which embraces them both. The mythical image of the hunter. Anyone is, in our opinion, a paradigmatic clement in this from of "meeting" which takes place within an impersonal and illusionary dimension.