ERIC Educational Resources Information Center
Mapotse, Tomé Awshar
2015-01-01
This article is based on a preliminary action research (AR) study conducted with selected schools in Limpopo. It intends to report on the progress made and research problem identified during the reconnaissance/preliminary study. The aim of this preliminary research is to ascertain whether the findings conform to the main research question of the…
Preliminary development of the adolescent students' basic psychological needs at school scale.
Tian, Lili; Han, Mengmeng; Huebner, E Scott
2014-04-01
The aim of the present study was to develop and provide evidence for the validity of a new measure of adolescent students' psychological need satisfaction at school, using a sample of Chinese students. We conducted four studies with four independent samples (total n = 1872). The first study aimed to develop items for the new instrument and to ascertain its factorial structure using exploratory factor analysis procedures. The second study aimed to examine the instrument's factorial structure using confirmatory factor analysis procedures as well as to assess its internal consistency reliability, convergent and divergent validity. The third study aimed to assess its measurement invariance across gender and age. The fourth study aimed to test its test-retest reliability over time and predictive validity. These preliminary results showed that the new instrument has promising psychometric properties. The potential contributions of the new instrument for future research and educational practices were discussed. Copyright © 2014 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.
Factorial Structure of the Pain Rehabilitation Expectations Scale: A Preliminary Study
ERIC Educational Resources Information Center
Cheing, Gladys L. Y.; Lai, Amy K. M.; Vong, Sinfia K. S.; Chan, Fong H.
2010-01-01
The aim of this study was to report the preliminary validation results for the Pain Rehabilitation Expectations Scale (PRES). The PRES is a clinical tool developed to measure the expectations about rehabilitation treatment and outcome for people with back pain. Fifty people with chronic back pain were recruited from 11 physiotherapy outpatient…
ERIC Educational Resources Information Center
Donohoe, Claire; Topping, Keith; Hannah, Elizabeth
2012-01-01
This preliminary study investigated the impact of the online interactive programme Brainology (which aimed to encourage a growth mindset) on the mindset, resiliency and sense of mastery of secondary school pupils. A quasi-experimental pre-, post- and follow-up mixed-methods study was carried out with 33 participants aged 13-14 years. The measures…
Automated Iodine Monitoring System Development (AIMS). [shuttle prototype
NASA Technical Reports Server (NTRS)
1975-01-01
The operating principle of the automated iodine monitoring/controller system (AIMS) is described along with several design modifications. The iodine addition system is also discussed along with test setups and calibration; a facsimile of the optical/mechanical portion of the iodine monitor was fabricated and tested. The appendices include information on shuttle prototype AIMS, preliminary prime item development specifications, preliminary failure modes and effects analysis, and preliminary operating and maintenance instructions.
Preliminary Validation of the Child Abuse Potential Inventory in Turkey
ERIC Educational Resources Information Center
Kutsal, Ebru; Pasli, Figen; Isikli, Sedat; Sahin, Figen; Yilmaz, Gokce; Beyazova, Ufuk
2011-01-01
This study aims to provide preliminary findings on the validity of Child Abuse Potential Inventory (CAP Inventory) on Turkish sample of 23 abuser and 47 nonabuser parents. To investigate validity in two groups, Minnesota Multiphasic Personality Inventory (MMPI) Psychopathic Deviate (MMPI-PD) scale is also used along with CAP. The results show…
Teaching in Rural Turkey: Pre-Service Teacher Perspectives
ERIC Educational Resources Information Center
Kizilaslan, Irem
2012-01-01
Despite preliminary findings that preparing teachers for rural positions is of great importance in Turkey's conditions, little has been reported regarding the measures that need to be addressed in order to effectively prepare teachers for remote areas. In response to this gap, the present study aimed to provide some preliminary views about the…
ERIC Educational Resources Information Center
Searl, Jeff; Knollhoff, Stephanie; Barohn, Richard J.
2017-01-01
Purpose: This preliminary study on lingual-alveolar contact pressures (LACP) in people with amyotrophic lateral sclerosis (ALS) had several aims: (a) to evaluate whether the protocol induced fatigue, (b) to compare LACP during speech (LACP-Sp) and during maximum isometric pressing (LACP-Max) in people with ALS (PALS) versus healthy controls, (c)…
ERIC Educational Resources Information Center
Caputo, Andrea; Rastelli, Valentina
2014-01-01
This study provides preliminary evidence from an Italian in-service training program addressed to lower secondary school teachers which supports school improvement plans (SIPs). It aims at exploring the association between characteristics/contents of SIPs and student improvement in math achievement. Pre-post standardized tests and text analysis of…
ERIC Educational Resources Information Center
Granville, Arthur C.; And Others
This executive summary presents the major findings of Interim Report III, which reports preliminary evaluation of Project Developmental Continuity (PDC). A Head Start demonstration program, PDC is aimed at promoting greater educational and developmental continuity as children make the transition from preschool to school. The report addresses three…
ERIC Educational Resources Information Center
Maruyama, Yukiko; Kanoh, Hiroko; Adachi, Kinya
2017-01-01
To investigate parents' concerns about programming education in primary school, a preliminary online survey was carried out as a first step of the study. The result of the survey shows that parents seem to think that aim of programming education in primary school is not only learning coding. [For the complete proceedings, see ED579395.
ERIC Educational Resources Information Center
En, Lydea Gn Wei; Brebner, Chris; McCormack, Paul
2014-01-01
Background: There are no published data on typical phonological development for Singaporean children. There is therefore the risk that children's speech in Singapore may be misdiagnosed or that clinicians may set goals erroneously. Aims: This paper reports a preliminary study on the English phonology of typically developing 4;0-4;5-year-old…
ERIC Educational Resources Information Center
Casenhiser, Devin M.; Shanker, Stuart G.; Stieben, Jim
2013-01-01
The study evaluates a social-communication-based approach to autism intervention aimed at improving the social interaction skills of children with autism spectrum disorder. We report preliminary results from an ongoing randomized controlled trial of 51 children aged 2 years 0 months to 4 years 11 months. Participants were assigned to either a…
NASA Technical Reports Server (NTRS)
King, R. B.; Fordyce, J. S.; Antoine, A. C.; Leibecki, H. F.; Neustadter, H. E.; Sidik, S. M.; Burr, J. C.; Craig, G. T.; Cornett, C. L.
1974-01-01
Preliminary review of a study of trace elements and compound concentrations in the ambient suspended particulate matter in Cleveland, Ohio, measured from August 1971 through June 1973, as a function of source, monitoring location, and meteorological conditions. The study is aimed at the development of techniques for identifying specific pollution sources which could be integrated into a practical system readily usable by an enforcement agency.
Hepburn, Silvia R; Crane, Catherine; Barnhofer, Thorsten; Duggan, Danielle S; Fennell, Melanie J V; Williams, J Mark G
2009-06-01
Thought suppression is a strategy aimed at mental control that may paradoxically increase the frequency of unwanted thoughts. This preliminary study examined effects of mindfulness-based cognitive therapy (MBCT) on thought suppression and depression in individuals with past depression and suicidality. In a randomized controlled trial design, 68 participants were allocated to an MBCT group or a treatment-as-usual waitlist control. Measures of thought suppression and depression were taken pre- and post-treatment. MBCT did not reduce thought suppression as measured by the White Bear Suppression Inventory, but significantly reduced self-reported attempts to suppress in the previous week. Preliminary evidence suggests that MBCT for suicidality may reduce thought suppression, but differential effects on thought suppression measures warrant further studies.
A preliminary neutron crystallographic study of thaumatin
DOE Office of Scientific and Technical Information (OSTI.GOV)
Teixeira, Susana C. M.; Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble; EPSAM and ISTM, Keele University, Staffordshire ST5 5BG
2008-05-01
Preliminary neutron crystallographic data from the sweet protein thaumatin have been recorded using the LADI-III diffractometer at the Institut Laue Langevin (ILL). The results illustrate the feasibility of a full neutron structural analysis aimed at further understanding the molecular basis of the perception of sweet taste. Such an analysis will exploit the use of perdeuterated thaumatin. A preliminary neutron crystallographic study of the sweet protein thaumatin is presented. Large hydrogenated crystals were prepared in deuterated crystallization buffer using the gel-acupuncture method. Data were collected to a resolution of 2 Å on the LADI-III diffractometer at the Institut Laue Langevin (ILL).more » The results demonstrate the feasibility of a full neutron crystallographic analysis of this structure aimed at providing relevant information on the location of H atoms, the distribution of charge on the protein surface and localized water in the structure. This information will be of interest for understanding the specificity of thaumatin–receptor interactions and will contribute to further understanding of the molecular mechanisms underlying the perception of taste.« less
Schacht, M J; Toustrup, C B; Madsen, L B; Martiny, M S; Larsen, B B; Simonsen, J T
2016-10-01
Rapid on-site evaluation (ROSE) of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) followed by a subsequent preliminary adequacy assessment and a preliminary diagnosis, was performed at Aarhus University Hospital by biomedical scientists (BMS). The aim of this study was to evaluate the BMS accuracy of ROSE adequacy assessment, the preliminary adequacy assessment and the preliminary diagnosis as compared with the cytopathologist-rendered final adequacy assessment and final diagnosis. The BMS-rendered assessments for 717 sites from 319 consecutive patients over a 4-month period were compared with the cytopathologist-rendered assessments. Comparisons of adequacy and preliminary diagnoses were based on inter-observer Cohen's Kappa coefficient with a 95% confidence interval (CI). Strong correlations between ROSE and final adequacy assessments [Kappa coefficient of 0.90 (CI: 0.85-0.96)] and between the preliminary and final adequacy assessments [Kappa coefficient of 0.93 (CI: 0.87-0.99)] were found. As for the correlation between the preliminary and final diagnoses, the Kappa coefficient was 0.99 (CI: 0.98-1). Both ROSE and preliminary adequacy assessments as well as preliminary diagnoses, all performed by BMS, were highly accurate when compared with the final assessment by the cytopathologist. © 2016 John Wiley & Sons Ltd.
Preliminary Analysis of the BASALA-H Experimental Programme
DOE Office of Scientific and Technical Information (OSTI.GOV)
Blaise, Patrick; Fougeras, Philippe; Philibert, Herve
2002-07-01
This paper is focused on the preliminary analysis of results obtained on the first cores of the first phase of the BASALA (Boiling water reactor Advanced core physics Study Aimed at mox fuel Lattice) programme, aimed at studying the neutronic parameters in ABWR core in hot conditions, currently under investigation in the French EOLE critical facility, within the framework of a cooperation between NUPEC, CEA and Cogema. The first 'on-line' analysis of the results has been made, using a new preliminary design and safety scheme based on the French APOLLO-2 code in its 2.4 qualified version and associated CEA-93 V4more » (JEF-2.2) Library, that will enable the Experimental Physics Division (SPEx) to perform future core designs. It describes the scheme adopted and the results obtained in various cases, going to the critical size determination to the reactivity worth of the perturbed configurations (voided, over-moderated, and poisoned with Gd{sub 2}O{sub 3}-UO{sub 2} pins). A preliminary study on the experimental results on the MISTRAL-4 is resumed, and the comparison of APOLLO-2 versus MCNP-4C calculations on these cores is made. The results obtained show very good agreements between the two codes, and versus the experiment. This work opens the way to the future full analysis of the experimental results of the qualifying teams with completely validated schemes, based on the new 2.5 version of the APOLLO-2 code. (authors)« less
The Impact of Involving Students in Managing the Quality of Higher Education Provision
ERIC Educational Resources Information Center
Garwe, Evelyn Chiyevo
2015-01-01
This study was aimed at exploring the power of student involvement in improving quality of higher educational provision in private higher education institutions in Zimbabwe. A longitudinal approach involving two separate surveys and covering a period of three years was used. A preliminary survey aimed at assessing the issues that impact negatively…
Development of Mathematics Course Attitude Scale: A Preliminary Study of Validity & Reliability
ERIC Educational Resources Information Center
Eskici, Menekse; Ilgaz, Gökhan; Aricak, Osman Tolga
2017-01-01
The aim of this research is to develop a Mathematics Course Attitude Scale to measure high school students' attitudes towards mathematics and to test the validity and reliability of this scale. It is also aimed to reveal whether there are significant differences in school students' attitudes towards mathematics according to their gender and…
Gratwick-Sarll, Kassandra; Bentley, Caroline
2014-01-01
A repeated measures, uncontrolled, preliminary evaluation of a single 3-hour workshop-"Should I Say Something?"-aimed at improving eating disorders mental health literacy, was conducted in a sample of 177 university undergraduates. Following participation in the workshop, significant increases in eating disorder recognition and knowledge, and significant decreases in stigmatizing attitudes, were reported by participants. Moreover, 85% of participants reported that they provided assistance to someone whom they suspected had a mental health condition, including an eating disorder, during the 3-month follow-up period. This study provides preliminary evidence that "Should I Say Something?" may be effective in improving the mental health literacy of young people.
Whole body pointing movements in transient microgravity: preliminary results.
Tagliabue, Michele; Pedrocchi, Alessandra; Gower, Valerio; Ferrigno, Giancarlo; Pozzo, Thierry
2004-07-01
The aim of the present study is a better comprehension of strategies of motor coordination during complex movements. In this field of research microgravity represent a unique experimental condition for the investigation of the role of equilibrium control in movement planning. Namely, here we focus on two important issues: the centre of mass control and the endpoint trajectory. Preliminary results of the center of mass position and the finger path curvature during pointing movements performed under normal and transient microgravity conditions are presented.
Paiva, Carlos Eduardo; Paiva, Bianca Sakamoto Ribeiro; de Castro, Rafael Amaral; Souza, Cristiano de Pádua; de Paiva Maia, Yara Cristina; Ayres, Jairo Aparecido; Michelin, Odair Carlito
2013-03-01
The aim of this preliminary study was to investigate whether religious practice can modify quality of life (QoL) in BC patients during chemotherapy. QoL and religion practice questionnaire (RPQ) scores were evaluated in a sample of BC patients in different moments. Before chemotherapy initiation, women with lower physical and social functional scores displayed higher RPQ scores. On the other hand, low RPQ patients worsened some QoL scores over time. Body image acceptance was positively correlated with religious practice and specifically praying activity. This preliminary study suggests the importance of religion in coping with cancer chemotherapy.
Bünder, Peter
2011-01-01
Marte Meo is a low-intensity programme of counselling parents and other persons significantly involved with children which aims to foster parenting capacity and facilitate child development. The article describes a preliminary pilot study with the aim of identifying variables for the future evaluation of efficacy and effectiveness of the Marte Meo method.
ERIC Educational Resources Information Center
Salvas, Marie-Claude; Vitaro, Frank; Brendgen, Mara; Cantin, Ste´phane
2016-01-01
Positive friendships have been related to decreasing levels of children's physical aggression over time. While this evidence calls for interventions aimed at helping children build good-quality friendships, tests of causality through experimental manipulations are still needed. The goal of this study was to examine whether an intervention aimed to…
Life Stories of Parents with Autistic Children
ERIC Educational Resources Information Center
Kocabiyik, Oya Onat; Fazlioglu, Yesim
2018-01-01
The major aim of this study was to determine how children diagnosed with autism shapes their parents' lives by specifying parents? life stories. The study group consisted of 10 parents who have children with autism. Parents who have participated in the study were determined through a preliminary interview prior to the study and in-depth interviews…
Ethics for Industrial Technology
ERIC Educational Resources Information Center
Rosentrater, Kurt A.; Balamuralikrishna, Radha
2005-01-01
This paper takes aim at one specific, as well as basic, need in teamwork and interdisciplinary projects--ethics and its implications for professional practice. A preliminary study suggests that students majoring in industrial technology degree programs may not have adequate opportunity to formally study and engage in ethical aspects of technology…
ERIC Educational Resources Information Center
Loucas, Tom; Riches, Nick Greatorex; Charman, Tony; Pickles, Andrew; Simonoff, Emily; Chandler, Susie; Baird, Gillian
2010-01-01
Background: The cognitive bases of language impairment in specific language impairment (SLI) and autism spectrum disorders (ASD) were investigated in a novel non-word comparison task which manipulated phonological short-term memory (PSTM) and speech perception, both implicated in poor non-word repetition. Aims: This study aimed to investigate the…
Increasing Parent Involvement in Youth HIV Prevention: A Randomized Caribbean Study
ERIC Educational Resources Information Center
Baptiste, Donna R.; Kapungu, Chisina; Miller, Steve; Crown, Laurel; Henry, David; Da Costa Martinez, Dona; Jo-Bennett, Karen
2009-01-01
This article presents preliminary findings of a randomized HIV prevention study in Trinidad and Tobago in the Caribbean. The study centers on a family HIV workshop aimed at strengthening parenting skills that are empirically linked to reducing adolescent HIV exposure and other sexual risks. These skills include parental monitoring; educating youth…
Online Activities of Urban Malaysian Adolescents: Report of a Pilot Study
ERIC Educational Resources Information Center
Tan, Kok Eng; Yen Abdullah, Melissa Ng Lee; Guan Saw, Kim
2012-01-01
The literacy practices of many communities today show new ways of meaning making in the contemporary, technological and digital culture. A number of Malaysian adolescents belong to this culture. This pilot study reports the preliminary findings of a larger study aimed at describing the online activities of Malaysian adolescents. Fifty-four…
Pressurized Wideband Absorbance Findings in Healthy Neonates: A Preliminary Study
ERIC Educational Resources Information Center
Wali, Hamzah A.; Mazlan, Rafidah; Kei, Joseph
2017-01-01
Purpose: The present study aimed to establish normative data for wideband absorbance (WBA) measured at tympanometric peak pressure (TPP) and 0 daPa and to assess the test-retest reliability of both measurements in healthy neonates. Method: Participants of this cross-sectional study included 99 full-term neonates (165 ears) with mean chronological…
Creativity, Bipolar Disorder Vulnerability and Psychological Well-Being: A Preliminary Study
ERIC Educational Resources Information Center
Gostoli, Sara; Cerini, Veronica; Piolanti, Antonio; Rafanelli, Chiara
2017-01-01
The aim of this research was to investigate the relationships between creativity, subclinical bipolar disorder symptomatology, and psychological well-being. The study method was of descriptive, correlational type. Significant tests were performed using multivariate regression analysis. Students of the 4th grade of 6 different Italian colleges…
Effect of Hypertextual Reading on Academic Success and Comprehension Skills
ERIC Educational Resources Information Center
Durukan, Erhan
2014-01-01
As computer technology developed, hypertexts emerged as an influential environment for developing language skills. This study aims to evaluate a text prepared in a hypertextual environment and its effects on academic success and comprehension skills. In this study, "preliminary test final test control group experimental pattern" was used…
NASA Astrophysics Data System (ADS)
Alan, G.; Tercan, M.
2017-10-01
Needlepunched nonwoven textiles are commonly used as geotextiles for various applications. Considering both environmental and economical benefits, utilization of recycled fibres in nonwoven geotextiles has become an attractive issue. Within this scope, the aim of this study is to evaluate the puncture resistance performances of top and bottom layers of multi-layered needle punched nonwovens made of recycled fibres to be used as membrane protective geotextiles by comparing them with those of made from polypropylene and polyester fibres. Puncture resistance results indicated that nonwovens made of recycled fibres demonstrated good performances at this preliminary stage.
Personalized Support for Chronic Conditions
D’Antrassi, Pierluigi; Ajčević, Miloš; Stellato, Kira; Di Lenarda, Andrea; Marceglia, Sara; Accardo, Agostino
2016-01-01
Summary Objective Solutions for improving management of chronic conditions are under the attention of healthcare systems, due to the increasing prevalence caused by demographic change and better survival, and the relevant impact on healthcare expenditures. The objective of this study was to propose a comprehensive architecture of a mHealth system aimed at boosting the active and informed participation of patients in their care process, while at the same time overcoming the current technical and psychological/clinical issues highlighted by the existing literature. Methods After having studied the current challenges outlined in the literature, both in terms of technological and human requirements, we focused our attention on some specific psychological aspects with a view to providing patients with a comprehensive and personalized solution. Our approach has been reinforced through the results of a preliminary assessment we conducted on 22 patients with chronic conditions. The main goal of such an assessment was to provide a preliminary understanding of their needs in a real context, both in terms of self-awareness and of their predisposition toward the use of IT solutions. Results According to the specific needs and features, such as mindfulness and gamification, which were identified through the literature and the preliminary assessment, we designed a comprehensive open architecture able to provide a tailor-made solution linked to specific individuals’ needs. Conclusion The present study represents the preliminary step towards the development of a solution aimed at enhancing patients’ actual perception and encouraging self-management and self-awareness for a better lifestyle. Future work regards further identification of pathology-related needs and requirements through focus groups including all stakeholders in order to describe the architecture and functionality in greater detail. PMID:27452661
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wendt, Fabian F; Damiani, Rick R
This poster summarizes the scope and preliminary results of a study conducted for the Bureau of Safety and Environmental Enforcement aimed at quantifying differences between two modeling approaches (fully coupled and sequentially coupled) through aero-hydro-servo-elastic simulations of two offshore wind turbines on a monopile and jacket substructure.
Sex, Drugs and STDs: Preliminary Findings from the Belfast Youth Development Study
ERIC Educational Resources Information Center
McAloney, Kareena; McCrystal, Patrick; Percy, Andrew
2010-01-01
Young people's participation in sexual risk behaviours is commonly linked with participation in a range of other risky behaviours, and in particular with substance use behaviours. This cross-sectional analysis of the sixth sweep of the Belfast Youth Development Study aimed to examine associations between substance use and sexual activity and…
Emotional Intelligence in Applicant Selection for Care-Related Academic Programs
ERIC Educational Resources Information Center
Zysberg, Leehu; Levy, Anat; Zisberg, Anna
2011-01-01
Two studies describe the development of the Audiovisual Test of Emotional Intelligence (AVEI), aimed at candidate selection in educational settings. Study I depicts the construction of the test and the preliminary examination of its psychometric properties in a sample of 92 college students. Item analysis allowed the modification of problem items,…
Short Animation Movies as Advance Organizers in Physics Teaching: A Preliminary Study
ERIC Educational Resources Information Center
Koscianski, Andre; Ribeiro, Rafael Joao; da Silva, Sani Carvalho Rutz
2012-01-01
Background: Advance organizers are instructional materials that help students use previous knowledge to make links with new information. Short animation movies are a possible format and are well suited for physics, as they can portray dynamic phenomena and represent abstract concepts. Purpose: The study aimed to determine guidelines for the…
Bullying Experiences among Children and Youth with Autism Spectrum Disorders
ERIC Educational Resources Information Center
Cappadocia, M. Catherine; Weiss, Jonathan A.; Pepler, Debra
2012-01-01
Few studies have investigated bullying experiences among children diagnosed with autism spectrum disorders (ASD); however, preliminary research suggests that children with ASD are at greater risk for being bullied than typically developing peers. The aim of the current study was to build an understanding of bullying experiences among children with…
ERIC Educational Resources Information Center
Kampourakis, Kostas; Zogza, Vasso
2009-01-01
This study aimed to explore secondary students' explanations of evolutionary processes, and to determine how consistent these were, after a specific evolution instruction. In a previous study it was found that before instruction students provided different explanations for similar processes to tasks with different content. Hence, it seemed that…
Children with Disabilities: Constructing Metaphors and Meanings through Art
ERIC Educational Resources Information Center
Saldaña, Claudia
2016-01-01
The aim of this qualitative study is to explore how art, as a semiotic tool, transforms children with disabilities. To achieve this purpose, one must listen to the voices of teachers and childcare workers in the field of special education. The study's preliminary findings found three main categories through data analysis: 1) Teachers' perceptions…
Aspiration to Enrol Children in Islamic Studies: A Case of Academicians
ERIC Educational Resources Information Center
Islam, Tazul; Zayed, Tareq M.
2016-01-01
Purpose: A preliminary observation reveals that children of Islamic studies (IS) academicians do not choose IS as their career discipline. In view of this, this paper aims to explore the dimensions of parental attitudes, behaviours, perceptions and aspirations in seeing a future in IS for their children. Design/methodology/approach: Fifteen…
African American and Caucasian Attempters Compared for Suicide Risk Factors: A Preliminary Study
ERIC Educational Resources Information Center
Roy, Alec
2003-01-01
The aim of the study was to compare African American and Caucasian substance dependent suicide attempters for risk factors for suicidal behavior. One hundred and fifty-eight African American and 95 Caucasian substance dependent patients who had attempted suicide were interviewed and their family history of suicidal behavior recorded. Patients…
ERIC Educational Resources Information Center
Watson, Candice C.; Rich, Brendan A.; Sanchez, Lisa; O'Brien, Kelly; Alvord, Mary K.
2014-01-01
Background: There is a lack of research examining the feasibility of group psychotherapy interventions for anxious children in private clinical service settings. Furthermore, no research to date has examined the effectiveness of resilience-based interventions for helping children with anxiety disorders. Objective: The present study aims to examine…
ERIC Educational Resources Information Center
Enticott, Peter G.; Rinehart, Nicole J.; Tonge, Bruce J.; Bradshaw, John L.; Fitzgerald, Paul B.
2010-01-01
Aim: Controversy surrounds the distinction between high-functioning autism (HFA) and Asperger disorder, but motor abnormalities are associated features of both conditions. This study examined motor cortical inhibition and excitability in HFA and Asperger disorder using transcranial magnetic stimulation (TMS). Method: Participants were diagnosed by…
Preliminary assessments of CO2 storage in carbonate formations: a case study from Malaysia
NASA Astrophysics Data System (ADS)
Raza, Arshad; Gholami, Raoof; Rezaee, Reza; Bing, Chua Han; Nagarajan, Ramasamy; Hamid, Mohamed Ali
2017-06-01
The preliminary assessment of depleted reservoirs prior to the injection of CO2 is an essential step to ensure the safety and success of storage projects. Several studies have provided a preliminary assessment of depleted reservoirs as a sequestration practice. However, the screening criteria used in these studies were not able to consider all of the aspects of a storage site. The aim of this paper is to provide a reservoir-scale evaluation approach for long-term storage practice in an offshore carbonate field located in Malaysia. Recently developed screening criteria that cover the key aspects of storage sites, such as capacity, injectivity, trapping mechanisms, and containment, are taken into consideration for the purpose of this study. The results obtained suggest that the reservoir has good potential to be a storage place for CO2, although the compaction behavior and aquifer supports of the reservoir might cause some difficulties. It is, therefore, recommended that a series of experimental and numerical studies on different aspects of storage sites be performed to ensure that injectivity is not a problem when it comes to the implementation stage.
Problem Analysis: Application in Developing Marketing Strategies for Colleges.
ERIC Educational Resources Information Center
Martin, John; Moore, Thomas
1991-01-01
The problem analysis technique can help colleges understand students' salient needs in a competitive market. A preliminary study demonstrates the usefulness of the approach for developing strategies aimed at maintaining student loyalty and improving word-of-mouth promotion to other prospective students. (Author/MSE)
A preliminary study of aquaporin 1 immunolocalization in chronic subdural hematoma membranes.
Basaldella, Luca; Perin, Alessandro; Orvieto, Enrico; Marton, Elisabetta; Itskevich, David; Dei Tos, Angelo Paolo; Longatti, Pierluigi
2010-07-01
Aquaporin 1 (AQP1) is a molecular water channel expressed in many anatomical locations, particularly in epithelial barriers specialized in water transport. The aim of this study was to investigate AQP1 expression in chronic subdural hematoma (CSDH) membranes. In this preliminary study, 11 patients with CSDH underwent burr hole craniectomy and drainage. Membrane specimens were stained with a monoclonal antibody targeting AQP1 for immunohistochemical analysis. The endothelial cells of the sinusoid capillaries of the outer membranes exhibited an elevated immunoreactivity to AQP1 antibody compared to the staining intensity of specimens from the inner membrane and normal dura. These findings suggest that the outer membrane might be the source of the increased fluid accumulation responsible for chronic hematoma enlargement.
ERIC Educational Resources Information Center
Cheng, Ivy K. Y.; Chan, Karen M. K.; Wong, C. S.; Cheung, Raymond T. F.
2015-01-01
Background: There is growing evidence of potential benefits of repetitive transcranial magnetic stimulation (rTMS) in the rehabilitation of dysphagia. However, the site and frequency of stimulation for optimal effects are not clear. Aims: The aim of this pilot study is to investigate the short-term effects of high-frequency 5 Hz rTMS applied to…
ERIC Educational Resources Information Center
Stadnick, Nicole A.; Stahmer, Aubyn; Brookman-Frazee, Lauren
2015-01-01
This is a pilot study of the effectiveness of Project ImPACT, a parent-mediated intervention for ASD delivered in a community program. The primary aim was to compare child and parent outcomes between the intervention group and a community comparison for 30 young children with ASD at baseline and 12 weeks. The secondary aim was to identify parent…
A Study of EL2 Pilots' Radio Communication in the General Aviation Environment
ERIC Educational Resources Information Center
Estival, Dominique; Molesworth, Brett
2009-01-01
This paper reports on the preliminary stages of a project designed to investigate communication problems in General Aviation and assess the utility of language technologies as a means of mitigation. The study presented in this paper is the first of a three-part study, in which we aim to investigate the extent to which the English language…
Vijayaram, Seerangaraj; Kannan, Suruli; Saravanan, Konda Mani; Vasantharaj, Seerangaraj; Sathiyavimal, Selvam; P, Palanisamy Senthilkumar
2016-05-01
The presence study was aimed to catalyze the primary metabolites and their confirmation by using GC-MS analysis and antibacterial potential of leaf extract of two important medicinal plant viz., Eucalyptus and Azadirachta indica. The antibacterial potential of the methanol leaf extract of the studied species was tested against Escherichia coli, Pseudomonas aeruginosa, Klebsiellap neumoniae, Streptococcus pyogens, Staphylococcus aureus using by agar well diffusion method. The higher zone of inhibition (16mm) was observed against the bacterium Pseudomonas aeruginosa at 100μl concentration of methanol leaf extract. Preliminary phytochemical analysis of studied species shows that presence of phytochemical compounds like steroids, phenolic compounds and flavonoids. GC-MS analysis confirms the occurrence of 20 different compounds in the methanol leaf extract of the both studied species.
ERIC Educational Resources Information Center
Granville, Arthur; And Others
This interim report re-examines data on instrument suitability, comparability of groups, and adequacy of sample size in Year III of the process evaluation of Project Developmental Continuity (PDC) and offers preliminary recommendations concerning the feasibility of continuing the impact study. PDC is a Head Start demonstration program aimed at…
ERIC Educational Resources Information Center
Degeneffe, Charles Edmund; Green, Richard; Jones, Clair
2016-01-01
Purpose: The study aimed to understand how use and satisfaction with services following discharge from an acquired brain injury (ABI) acute-care facility related to family caregiver outcomes. Methods: A correlational and descriptive study design was used. Nineteen primary family caregivers of persons recently discharged from an ABI acute-care…
ERIC Educational Resources Information Center
Trend, Roger David
2001-01-01
Studies (n=51) inservice school teachers with regard to their orientations toward geoscience phenomena in general and deep time in particular. Aims to identify the nature of idiosyncratic conceptions of deep time and propose a curricular Deep Time Framework for teacher education. (Contains 29 references.) (Author/YDS)
ERIC Educational Resources Information Center
Rosenblum, Sara; Aloni, Tsipi; Josman, Naomi
2010-01-01
Organizational ability constitutes one executive function (EF) component essential for common everyday performance. The study aim was to explore the relationship between handwriting performance and organizational ability in school-aged children. Participants were 58 males, aged 7-8 years, 30 with dysgraphia and 28 with proficient handwriting.…
The Challenges of Chinese: A Preliminary Study of UK Learners' Perceptions of Difficulty
ERIC Educational Resources Information Center
Hu, Bo
2010-01-01
This study aims to highlight aspects of difficulty encountered by Chinese as a Foreign Language (CFL) learners and to explore the factors underlying these aspects. Data were gathered through a Chinese Language Learning Difficulty Survey from 164 CFL learners, mostly in British higher education. The survey data provided useful exploratory findings.…
ERIC Educational Resources Information Center
Strotmann, Birgit; Bamond, Victoria; Lopez Lago, Jose Maria; Bailen, Maria; Bonilla, Sonia; Montesinos, Francisco
2014-01-01
Few studies have been conducted at the tertiary level on Content and Language Integrated Learning (CLIL). The current study aims to gather and share preliminary data concerning CLIL in higher education at several universities in different countries. A questionnaire and brief description of the project and its objectives were emailed to all…
Are Deep Strategic Learners Better Suited to PBL? A Preliminary Study
ERIC Educational Resources Information Center
Papinczak, Tracey
2009-01-01
The aim of this study was to determine if medical students categorised as having deep and strategic approaches to their learning find problem-based learning (PBL) enjoyable and supportive of their learning, and achieve well in the first-year course. Quantitative and qualitative data were gathered from first-year medical students (N = 213). All…
Serum Ionized Calcium Quantification for Staging Canine Periodontal Disease: A Preliminary Study.
Miguel Carreira, L; Daniela, Dias; Pedro, Azevedo
2015-06-01
Periodontal diseases (PD) are infectious, inflammatory, progressive diseases of the oral cavity affecting people and dogs. PD takes 2 forms: gingivitis and periodontitis. Diagnosing or staging PD can be achieved only with dental x-rays and periodontal probing, both of which require the use of general anesthesia in dogs. This study aimed to determine whether serum ionized calcium ([iCa(2+)]) levels can be useful in preliminary PD staging in dogs. A sample of 40 dogs (n = 40) was divided into 4 groups (n = 10 each) based on the following PD stages: G1 (gingivitis), G2 (initial periodontitis), G3 (moderate periodontitis), and G4 (severe periodontitis). The groups were then subjected to [iCa(2+)] quantification. Statistically significant differences were observed between PD stages and [iCa(2+)] for all stages except G3 and G4. Therefore, this parameter can be used as an additional tool to establish and monitor preliminary PD status. Copyright © 2015 Elsevier Inc. All rights reserved.
Factors Associated with the Participation of Children with Complex Communication Needs
ERIC Educational Resources Information Center
Clarke, M. T.; Newton, C.; Griffiths, T.; Price, K.; Lysley, A.; Petrides, K. V.
2011-01-01
The aim of this study was to conduct a preliminary analysis of relations between child and environmental variables, including factors related to communication aid provision, and participation in informal everyday activities in a sample of children with complex communication needs. Ninety-seven caregivers of children provided with communication…
Parent Experience of Implementing Effective Home Programs
ERIC Educational Resources Information Center
Novak, Iona
2011-01-01
The aim of this preliminary study was to describe parent views about implementing effective home programs to inform practice recommendations. Semi-structured interviews were conducted with 10 parents of children with cerebral palsy (2 fathers and 8 mothers) who had participated in a home program by using a partnership-based approach. Transcripts…
Universal Developmental Screening: Preliminary Studies in Galicia, Spain
ERIC Educational Resources Information Center
Sarmiento Campos, Jose A.; Squires, Jane; Ponte, Jaime
2011-01-01
"A_Tempo" is a research project that is currently under development in Galicia, an autonomous community of Spain. Its main aim is to propose an effective universal screening procedure for early identification of developmental disorders in children from zero to three years of age who attend Galician pre-primary schools.…
Cross Cultural Perspectives of Gender and Management in Universities
ERIC Educational Resources Information Center
White, K.; Riordan, S.; Ozkanli, O.; Neale, J.
2010-01-01
Aim: This article presents preliminary results of a cross cultural study of gender and management in universities. Methodology: Qualitative interviews with senior managers in each country were analysed in relation to key concepts of career paths, support, gate keeping, management skills, disciplinary factors, gendered leadership styles and…
Facilitating International Fieldwork: The Receptive Services of New Zealand's Geography Community
ERIC Educational Resources Information Center
Fuller, Ian C.
2015-01-01
This study aims to provide preliminary insight into facilitating international fieldwork in New Zealand by researchers and universities who support visiting university groups. Anonymous online surveys sought views of supporting researchers (15 respondents), and supported scholars (8 respondents). The extent to which international fieldwork is…
Depression in Adolescents with ASD: A Pilot RCT of a Group Intervention
ERIC Educational Resources Information Center
Santomauro, Damian; Sheffield, Jeanie; Sofronoff, Kate
2016-01-01
Depression is a potentially life threatening affective disorder that is highly prevalent in individuals with autism spectrum disorders (ASD). This study aimed to evaluate the feasibility, acceptability and preliminary efficacy of a cognitive behavioural intervention for depression in adolescents with ASD. Participants were randomly assigned to the…
Stakeholder Support for School Food Policy Expansions
ERIC Educational Resources Information Center
Pettigrew, Simone; Pescud, Melanie; Donovan, Robert J.
2012-01-01
The aim of this study was to assess the extent to which parents and school-based stakeholders (principals, teachers, canteen managers and Parents & Citizen Committee presidents) are supportive of potential expansions to a new school food policy. Eight additional policy components elicited in preliminary focus groups with parents and 19 additional…
Environmental literacy with green chemistry oriented in 21st century learning
NASA Astrophysics Data System (ADS)
Mitarlis, Ibnu, Suhadi; Rahayu, Sri; Sutrisno
2017-12-01
The aim of this study is to analyze the design of chemistry subject with green chemistry oriented to improve students' environmental literacy as one of the important requirements of 21st century learning. This research used R&D design which consisted of four stages, i.e. preliminary study, the study of literature, development of materials, and expert and empirical validation. This article presents the results of preliminary study and the study of literature. It can be concluded from the results of an analysis that environmental literacy is one of the important components of learning outcomes which should be pursued in 21st century teaching. Philosophy of green chemistry plays an important role to reduce and prevent pollution of environment. Principles of green chemistry can be integrated into learning environment as learning outcomes or nurturant effects of learning.
ERIC Educational Resources Information Center
Sánchez de Miguel, Manuel; Lizaso, Izarne; Hermosilla, Daniel; Alcover, Carlos-Maria; Goudas, Marios; Arranz-Freijó, Enrique
2017-01-01
Background: Research has shown that self-determination theory can be useful in the study of motivation in sport and other forms of physical activity. The Perceived Locus of Causality (PLOC) scale was originally designed to study both. Aim: The current research presents and validates the new PLOC-U scale to measure academic motivation in the…
Light ion production for a future radiobiological facility at CERN: Preliminary studies
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stafford-Haworth, Joshua, E-mail: Joshua.Stafford-Haworth@cern.ch; John Adams Institute at Royal Holloway, University of London, Egham, Surrey TW20 0EX; Bellodi, Giulia
2014-02-15
Recent medical applications of ions such as carbon and helium have proved extremely effective for the treatment of human patients. However, before now a comprehensive study of the effects of different light ions on organic targets has not been completed. There is a strong desire for a dedicated facility which can produce ions in the range of protons to neon in order to perform this study. This paper will present the proposal and preliminary investigations into the production of light ions, and the development of a radiobiological research facility at CERN. The aims of this project will be presented alongmore » with the modifications required to the existing linear accelerator (Linac3), and the foreseen facility, including the requirements for an ion source in terms of some of the specification parameters and the flexibility of operation for different ion types. Preliminary results from beam transport simulations will be presented, in addition to some planned tests required to produce some of the required light ions (lithium, boron) to be conducted in collaboration with the Helmholtz-Zentrum für Materialien und Energie, Berlin.« less
Light ion production for a future radiobiological facility at CERN: preliminary studies.
Stafford-Haworth, Joshua; Bellodi, Giulia; Küchler, Detlef; Lombardi, Alessandra; Röhrich, Jörg; Scrivens, Richard
2014-02-01
Recent medical applications of ions such as carbon and helium have proved extremely effective for the treatment of human patients. However, before now a comprehensive study of the effects of different light ions on organic targets has not been completed. There is a strong desire for a dedicated facility which can produce ions in the range of protons to neon in order to perform this study. This paper will present the proposal and preliminary investigations into the production of light ions, and the development of a radiobiological research facility at CERN. The aims of this project will be presented along with the modifications required to the existing linear accelerator (Linac3), and the foreseen facility, including the requirements for an ion source in terms of some of the specification parameters and the flexibility of operation for different ion types. Preliminary results from beam transport simulations will be presented, in addition to some planned tests required to produce some of the required light ions (lithium, boron) to be conducted in collaboration with the Helmholtz-Zentrum für Materialien und Energie, Berlin.
ERIC Educational Resources Information Center
Lin, Jin-Ding; Lin, Lan-Ping; Hsieh, Molly; Lin, Pei-Ying
2010-01-01
The present study aimed to describe the kidney function profile--serum creatinine and estimated glomerular filtration rate (eGFR), and to examine the relationships of predisposing factors to abnormal serum creatinine in people with intellectual disabilities (ID). Data were collected by a cross-sectional study of 827 aged 15-18 years adolescents…
ERIC Educational Resources Information Center
Meyer, Amanda J.; Armson, Anthony; Losco, C. Dominique; Losco, Barrett; Walker, Bruce F.
2015-01-01
It has been demonstrated that a positive correlation exists between clinical knowledge and retained concepts in basic sciences. Studies have demonstrated a modest attrition of anatomy knowledge over time, which may be influenced by students' perceived importance of the basic sciences and the learning styles adopted. The aims of this study were to:…
ERIC Educational Resources Information Center
Miniscalco, Carmela; Rudling, Maja; Råstam, Maria; Gillberg, Christopher; Johnels, Jakob Åsberg
2014-01-01
Background: Research in the last decades has clearly pointed to the important role of language and communicative level when trying to understand developmental trajectories in children with autism spectrum disorders (ASD). Aims: The purpose of this longitudinal study was to investigate whether (1) "core language skills", measured as…
ERIC Educational Resources Information Center
Martinez-Castilla, Pastora; Peppe, Susan
2008-01-01
This study aimed to find out what intonation features reliably represent the emotions of "liking" as opposed to "disliking" in the Spanish language, with a view to designing a prosody assessment procedure for use with children with speech and language disorders. 18 intonationally different prosodic realisations (tokens) of one word (limon) were…
ERIC Educational Resources Information Center
Dagnino, Francesca Maria; Ballauri, Margherita; Benigno, Vincenza; Caponetto, Ilaria; Pesenti, Elia
2013-01-01
This paper presents the results of preliminary research on the assessment of reasoning abilities in primary school poor achievers vs. normal achievers using computer game tasks. Subjects were evaluated by means of cognitive assessment on logical abilities and academic skills. The aim of this study is to better understand the relationship between…
ERIC Educational Resources Information Center
Panerai, Simonetta; Tasca, Domenica; Lanuzza, Bartolo; Trubia, Grazia; Ferri, Raffaele; Musso, Sabrina; Alagona, Giovanna; Di Guardo, Giuseppe; Barone, Concetta; Gaglione, Maria P.; Elia, Maurizio
2014-01-01
This report, based on four studies with children with low-functioning autism, aimed at evaluating the effects of repetitive transcranial magnetic stimulation delivered on the left and right premotor cortices on eye-hand integration tasks; defining the long-lasting effects of high-frequency repetitive transcranial magnetic stimulation; and…
ERIC Educational Resources Information Center
Anggraini, Purwati; Kusniarti, Tuti
2015-01-01
This current study aimed at investigating Bahasa Indonesia textbooks with regards to local wisdom issues. The preliminary study was utilized as the basis for developing instructional materials of Bahasa Indonesia that are rich of characters. Bahasa Indonesia instructional materials containing local wisdoms not only equip students with broad…
The Ambulatory Integration of the Medical and Social (AIMS) model: A retrospective evaluation.
Rowe, Jeannine M; Rizzo, Victoria M; Shier Kricke, Gayle; Krajci, Kate; Rodriguez-Morales, Grisel; Newman, Michelle; Golden, Robyn
2016-01-01
An exploratory, retrospective evaluation of Ambulatory Integration of the Medical and Social (AIMS), a care coordination model designed to integrate medical and non-medical needs of patients and delivered exclusively by social workers was conducted to examine mean utilization of costly health care services for older adult patients. Results reveal mean utilization of 30-day hospital readmissions, emergency department (ED) visits, and hospital admissions are significantly lower for the study sample compared to the larger patient population. Comparisons with national population statistics reveal significantly lower mean utilization of 30-day admissions and ED visits for the study sample. The findings offer preliminary support regarding the value of AIMS.
Koeneman, M M; Kruse, A J; Kooreman, L F S; Zur Hausen, A; Hopman, A H N; Sep, S J S; Van Gorp, T; Slangen, B F M; van Beekhuizen, H J; van de Sande, A J M; Gerestein, C G; Nijman, H W; Kruitwagen, R F P M
2017-02-07
The "TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia" (TOPIC) trial was stopped preliminary, due to lagging inclusions. This study aimed to evaluate the treatment efficacy and clinical applicability of imiquimod 5% cream in high-grade cervical intraepithelial neoplasia (CIN). The lagging inclusions were mainly due to a strong patient preference for either of the two treatment modalities. This prompted us to initiate a new study on the same subject, with a non-randomized, open-label design: the 'TOPical Imiquimod treatment of high-grade Cervical intraepithelial neoplasia (TOPIC)-3' study. Original TOPIC-trial: Medical Ethics Committee approval number METC13231; ClinicalTrials.gov Identifier: NCT02329171, 22 December 2014. TOPIC-3 study: Medical Ethics Committee approval number METC162025; ClinicalTrials.gov Identifier: NCT02917746, 16 September 2016.
Handwriting Capacity in Children Newly Diagnosed with Attention Deficit Hyperactivity Disorder
ERIC Educational Resources Information Center
Brossard-Racine, Marie; Majnemer, Annette; Shevell, Michael; Snider, Laurie; Belanger, Stacey Ageranioti
2011-01-01
Preliminary evidence suggests that children with Attention Deficit Hyperactivity Disorder (ADHD) may exhibit handwriting difficulties. However, the exact nature of these difficulties and the extent to which they may relate to motor or behavioural difficulties remains unclear. The aim of this study was to describe handwriting capacity in children…
ERIC Educational Resources Information Center
Walker, Denise D.; Roffman, Roger A.; Stephens, Robert S.; Wakana, Kim; Berghuis, James
2006-01-01
This study's aims were (a) to investigate the feasibility of a school-based motivational enhancement therapy (MET) intervention in voluntarily attracting adolescents who smoke marijuana regularly but who are not seeking formal treatment and (b) to evaluate the efficacy of the intervention in reducing marijuana use. Ninety-seven adolescents who had…
A Different Approach to Preparing Novakian Concept Maps: The Indexing Method
ERIC Educational Resources Information Center
Turan Oluk, Nurcan; Ekmekci, Güler
2016-01-01
People who claim that applying Novakian concept maps in Turkish is problematic base their arguments largely upon the structural differences between the English and Turkish languages. This study aims to introduce the indexing method to eliminate problems encountered in Turkish applications of Novakian maps and to share the preliminary results of…
ERIC Educational Resources Information Center
Koenig, Kathleen; White, Susan Williams; Pachler, Maryellen; Lau, Monika; Lewis, Moira; Klin, Ami; Scahill, Lawrence
2010-01-01
A randomized controlled design was employed to evaluate a social skills intervention for children with pervasive developmental disorders. Aims included evaluating the acceptability of the program and gathering preliminary evidence on efficacy. Forty-four children, ages 8-11 years, were randomly assigned to treatment or wait list. Treatment…
Learning Authentic Leadership in New Zealand: A Learner-Centred Methodology and Evaluation
ERIC Educational Resources Information Center
Roche, Maree
2010-01-01
This study provides preliminary examination of the efficacy of the "Best Authentic Leadership Self" exercise. A field quasi-experimental design was conducted with a dual purpose: (1) to ascertain the value of interventions aimed at triggering events to enhance the learning (c.f. teaching) of "authentic leadership? and how this…
Introductory Minicourse, Career Oriented Pre-Technical Physics. Preliminary Edition.
ERIC Educational Resources Information Center
Bullock, Bob; And Others
This minicourse was prepared for use with secondary physics students in the Dallas Independent School District. This is an introductory minicourse aimed at acquainting the student with the realm of physics so that the student can pursue further study by selecting those minicourses most relevant to his career needs and interests. The minicourse was…
Exploring the Temperament and Character Traits of Rural and Urban Doctors
ERIC Educational Resources Information Center
Eley, Diann; Young, Louise; Przybeck, Thomas R.
2009-01-01
Context: Australia shares many dilemmas with North America regarding shortages of doctors in rural and remote locations. This preliminary study contributes to the establishment of a psychobiological profile for rural doctors by comparing temperament and character traits with an urban cohort. Purpose: The aim was to compare the individual levels…
ERIC Educational Resources Information Center
Shen, I-Hsuan; Lee, Tsai-Yun; Chen, Chia-Ling
2012-01-01
Preliminary evidence suggests that handwriting difficulties are common to children with Attention Deficit Hyperactivity Disorder (ADHD). However, the nature of the task-specific impairments is needed to be clarified. The aim of this study was to describe handwriting capacity in ADHD children without DCD and identify underlying factors of…
ERIC Educational Resources Information Center
Adams, Catherine; Lloyd, Julian
2005-01-01
Background: The preliminary phase of a project aimed at establishing appropriate outcome measures for intervention with children who have pragmatic language impairments (PLI) is reported. Assessment methods for children with PLI are considered in the context of developing outcome measures for intervention studies. Communicative function…
Using media to promote suicide prevention hotlines to Veteran households.
Karras, Elizabeth; Stephens, Brady; Kemp, Janet E; Bossarte, Robert M
2014-02-01
This article presents preliminary evidence that media campaigns are valuable in promoting suicide prevention hotlines to Veteran households by reporting data from 2526 telephone surveys. Findings from this study underscore the need for further investigation of the use of media campaigns to support suicide prevention initiatives aimed at Veteran populations.
ERIC Educational Resources Information Center
Lee, Juyoung; Krause, Amanda E.; Davidson, Jane W.
2017-01-01
The aim of this study was to consider how we can invest in music-making to promote well-being in school contexts. Web-based data collection was conducted where researchers identified 17 case studies that describe successful music programs in schools in Australia. The researchers aligned content from these case studies into the five categories of…
Pamies-Aubalat, Lidia; Quiles-Marcos, Yolanda; Núñez-Núñez, Rosa M
2013-12-01
This study examined the Dieting Peer Competitiveness Scale; it is an instrument for evaluating this social comparison in young people. This instrumental study has two aims: The objective of the first aim was to present preliminary psychometric data from the Spanish version of the Dieting Peer Competitiveness Scale, including statistical item analysis, research about this instrument's internal structure, and a reliability analysis, from a sample of 1067 secondary school adolescents. The second objective of the study corresponds to confirmatory factor analysis of the scale's internal structure, as well as analysis for evidence of validity from a sample of 1075 adolescents.
NASA Astrophysics Data System (ADS)
Mani, Lara; Cole, Paul D.; Stewart, Iain
2016-07-01
This paper presents the findings from a study aimed at understanding whether video games (or serious games) can be effective in enhancing volcanic hazard education and communication. Using the eastern Caribbean island of St. Vincent, we have developed a video game - St. Vincent's Volcano - for use in existing volcano education and outreach sessions. Its twin aims are to improve residents' knowledge of potential future eruptive hazards (ash fall, pyroclastic flows and lahars) and to integrate traditional methods of education in a more interactive manner. Here, we discuss the process of game development including concept design through to the final implementation on St. Vincent. Preliminary results obtained from the final implementation (through pre- and post-test knowledge quizzes) for both student and adult participants provide indications that a video game of this style may be effective in improving a learner's knowledge. Both groups of participants demonstrated a post-test increase in their knowledge quiz score of 9.3 % for adults and 8.3 % for students and, when plotted as learning gains (Hake, 1998), show similar overall improvements (0.11 for adults and 0.09 for students). These preliminary findings may provide a sound foundation for the increased integration of emerging technologies within traditional education sessions. This paper also shares some of the challenges and lessons learnt throughout the development and testing processes and provides recommendations for researchers looking to pursue a similar study.
Design of Launcher Towards Spacecraft Comfort: Ariane 6 Objectives
NASA Astrophysics Data System (ADS)
Mourey, Patrick; Lambare, Hadrien; Valbuena, Matias F.
2014-06-01
Preliminary advanced studies were performed recently to select the possible concepts for a launcher that could succeed to Ariane 5. During the end of 2012 Space Ministry Conference, a configuration defining the propellant of the stages and the coarse staging ("PPH") was frozen in order to engage the preliminary selection concept studies. The first phase consisted to select the main features of the architecture in order to go deeper in the different matters or the advanced studies. The concept was selected mid of 2013.During all these phases of the preliminary project, different criteria (such as the recurring cost which is a major one) were used to quote the different concepts, among which the "payload comfort", ie the minimization of the environment generated by the launcher toward the satellites.The minimization of the environment was first expressed in term of objectives in the Mission Requirement Document (MRD) for the different mechanical environment such as quasi-static loads, dynamic loads, acoustics, shocks... Criteria such as usable volume, satellites frequency requirement and interface requirement are also expressed in the MRD.The definition of these different criteria was of course fixed taking benefit from the launcher operator experience based on a long story of dealing with spacecraft-launcher interface issues on Ariane, Soyouz and Vega. The general idea is to target improved or similar levels than those currently applicable for Ariane 5. For some environment for which a special need is anticipated from the potential end users, a special effort is aimed.The preliminary advanced study phase is currently running and has to address specific topics such as the definition of the upper part layout including geometry ofthe fairing, the definition of the launch pad with preliminary ideas to minimize acoustics and blast wave or first calculations on dimensioning dynamic load- cases such as thrust oscillations of the solid rocket motors (SRM).The present paper will give a very preliminary overview of the different topics in relation with these general launcher-spacecraft issues.
ERIC Educational Resources Information Center
Chen, C.-C.; Ringenbach, S. D. R.; Crews, D.; Kulinna, P. H.; Amazeen, Eric L.
2015-01-01
Background: This study was aimed at investigating the impact of a single exercise intervention on executive function in young adults with Down syndrome (DS). Methods: Considering the relations among executive function, physical and mental health and early onset of Alzheimer's disease in this population, we tested three components of executive…
ERIC Educational Resources Information Center
Higgins, Robert; Hogg, Peter; Robinson, Leslie
2013-01-01
This article discusses the piloting and evaluation of the Research-informed Teaching experience (RiTe) project. The aim of RiTe was to link teaching and learning with research within an undergraduate diagnostic radiography curriculum. A preliminary pilot study of RiTe was undertaken with a group of level 4 (year 1) volunteer BSc (Hons) diagnostic…
ERIC Educational Resources Information Center
Crino, Natalie; Djokvucic, Ivana
2010-01-01
Treatment outcome studies demonstrate that day-hospital programs are effective in the treatment of eating disorders. Few descriptions are available on the specifics of treatment, particularly the process of therapy. The group therapy modality is thought to provide important therapeutic benefits. The present study aimed to examine the association…
ERIC Educational Resources Information Center
Dominiak-Kochanek, Monika
2016-01-01
The aim of this study was to define whether, and to what extent identity formation in late adolescence is disability specific. Ninety-eight adolescents participated in this study, including 43 students with motor disability and 55 students without disability. Identity exploration and commitment was measured by the Utrecht-Groningen Identity…
Lahiri, Uttama; Trewyn, Adam; Warren, Zachary; Sarkar, Nilanjan
2011-01-01
Children with Autism Spectrum Disorder are often characterized by deficits in social communication skills. While evidence suggests that intensive individualized interventions can improve aspects of core deficits in Autism Spectrum Disorder, at present numerous potent barriers exist related to accessing and implementing such interventions. Researchers are increasingly employing technology to develop more accessible, quantifiable, and individualized intervention tools to address core vulnerabilities related to autism. The present study describes the development and preliminary application of a Virtual Reality technology aimed at facilitating improvements in social communication skills for adolescents with autism. We present preliminary data from the usability study of this technological application for six adolescents with autism and discuss potential future development and application of adaptive Virtual Reality technology within an intervention framework.
Kubayi, Alliance; Toriola, Abel; Didymus, Faye
2018-06-01
The aim of this series of studies was to develop and initially validate an instrument to assess stressors among South African sports coaches. In study one, a preliminary pool of 45 items was developed based on existing literature and an expert panel was employed to assess the content validity and applicability of these items. In study two, the 32 items that were retained after study one were analysed using principal component analysis (PCA). The resultant factorial structure comprised four components: environmental stressors, performance stressors, task-related stressors, and athlete stressors. These four components were made up of 26 items and, together, the components and items comprised the provisional Stressors in Sports Coaching Questionnaire (SSCQ). The results show that the SSCQ demonstrates acceptable internal consistency (.73-.89). The findings provide preliminary evidence that SSCQ is a valid tool to assess stressors among South African sports coaches.
ERIC Educational Resources Information Center
Misurell, Justin R.; Springer, Craig; Tryon, Warren W.
2011-01-01
This preliminary investigation examined the efficacy of a game-based cognitive-behavioral therapy group program for elementary school-aged children who have experienced sexual abuse. Treatment aimed to improve: (a) internalizing symptoms, (b) externalizing behaviors, (c) sexually inappropriate behaviors, (d) social skills deficits, (e) self-esteem…
Industrial solutions trends for the control of HiRes spectrograph@E-ELT
NASA Astrophysics Data System (ADS)
Di Marcantonio, P.; Baldini, V.; Calderone, G.; Cirami, R.; Coretti, I.; Cristiani, S.
Starting a few years ago, ESO initiated a number of projects aiming to explore the possible adoption of industrial standards and commercial off-the-shelf components (COTS) for the control of future VLT and E-ELT instrumentations. In this context, ESPRESSO, the next generation high-stability spectrograph for the VLT and to a certain extent, a precursor of HiRes, has adopted since the preliminary design phase those solutions. Based on the ESPRESSO experience and taking into account the requirements inferred from the preliminary Hi-Res studies in terms of both high-level operations as well as low-level control, I will present in this paper the current proposal for the HiRes hardware architecture.
Behavior of HepG2 liver cancer cells using microfluidic-microscopy: a preliminary study
NASA Astrophysics Data System (ADS)
Karamahmutoglu, Hande; ćetin, Metin; Yaǧcı, Tamer; Elitaş, Meltem
2018-02-01
Hepatocellular carcinoma is one of the most common types of liver cancer causing death all over the world. Although early-stage liver cancer can sometimes be treated with partial hepatectomy, liver transplantation, ablation, and embolization, sorafenib treatment is the only approved systemic therapy for advanced HCC. The aim of this research is to develop tools and methods to understand the individuality of hepatocellular carcinoma. Microfluidic cell-culture platform has been developed to observe behavior of single-cells; fluorescence microscopy has been implemented to investigate phenotypic changes of cells. Our preliminary data proved high-level heterogeneity of hepatocellular carcinoma while verifying limited growth of liver cancer cell lines on the silicon wafer.
The Effect of Verbal and Visuo-Spatial Abilities on the Development of Knowledge of the Earth
NASA Astrophysics Data System (ADS)
Kikas, Eve
2006-09-01
Difficulties in students’ understanding of the spherical model of the Earth have been shown in previous studies. One of the reasons for these difficulties lies in beliefs and preliminary knowledge that hinder the interpretation of the scientific knowledge, the other reason may lie in the low level of verbal and visuo-spatial abilities. The study aims to investigate the effect of verbal and visuo-spatial abilities, but also that of preliminary knowledge on the later development of the knowledge of the Earth in school. 176 schoolchildren (96 boys and 80 girls) from five schools were tested; the mean age of the children during the first interview was seven years and eight months. All students were interviewed twice in grades 1 and 2, before and after they had learnt the topic in school. Factual, scientific and synthetic knowledge was assessed. The facilitative effect of visuo-spatial and verbal abilities and preliminary factual and scientific knowledge on students’ knowledge of astronomy after having learnt the topic in school was shown. In contrast, the hindering effect of synthetic knowledge was not found.
Boyden, Paul; Knowles, Rebecca; Corcoran, Rhiannon; Hamilton, Simon; Rowse, Georgina
2015-01-01
A preliminary cognitive model of grandiose delusions has been put forward suggesting that persecutory and grandiose delusions shared distinct, yet overlapping psychological processes. This study aims to test this model and hypothesises that participants experiencing grandiose delusions may demonstrate a theory of mind (ToM) impairment and differences in attributional style compared to a control group. A cross-sectional design compared the performance of 18 individuals with grandiose delusions to a control group of 14 participants with depression. ToM was measured using a non-verbal joke appreciation task and a verbal stories task. Attributional style was measured using the internal, personal and situational attributions questionnaire. Participants experiencing grandiose delusions performed significantly worse on both ToM tasks compared to controls. Furthermore, these participants provided significantly more atypical answers when explaining the joke behind the ToM cartoons. No differences for subjective funniness ratings or attributional style were found. This preliminary study indicated participants experiencing grandiose delusions have ToM impairments which may contribute to the maintenance of this symptom.
4MOST systems engineering: from conceptual design to preliminary design review
NASA Astrophysics Data System (ADS)
Bellido-Tirado, Olga; Frey, Steffen; Barden, Samuel C.; Brynnel, Joar; Giannone, Domenico; Haynes, Roger; de Jong, Roelof S.; Phillips, Daniel; Schnurr, Olivier; Walcher, Jakob; Winkler, Roland
2016-08-01
The 4MOST Facility is a high-multiplex, wide-field, brief-fed spectrograph system for the ESO VISTA telescope. It aims to create a world-class spectroscopic survey facility unique in its combination of wide-field multiplex, spectral resolution, spectral coverage, and sensitivity. At the end of 2014, after a successful concept optimization design phase, 4MOST entered into its Preliminary Design Phase. Here we present the process and tools adopted during the Preliminary Design Phase to define the subsystems specifications, coordinate the interface control documents and draft the system verification procedures.
ERIC Educational Resources Information Center
Mestad, Idar; Kolstø, Stein Dankert
2017-01-01
This study aims to characterize a group of students' preliminary oral explanations of a scientific phenomenon produced as part of their learning process. The students were encouraged to use their own wordings to test out their own interpretation of observations when conducting practical activities. They presented their explanations orally in the…
Development of a Scale for Measuring Teachers' Attitudes toward Students' Inappropriate Behaviour
ERIC Educational Resources Information Center
Malak, Md. Saiful; Sharma, Umesh; Deppeler, Joanne M.
2017-01-01
This study aimed at developing a valid and reliable instrument for measuring attitudes of primary schoolteachers toward inappropriate student behaviour. A systematic approach was used to develop the scale. Results provide preliminary evidence that the new instrument (consisting of 13 items on a six-point Likert type scale) meets the standards for…
Teaching Programming in Secondary School: A Pedagogical Content Knowledge Perspective
ERIC Educational Resources Information Center
Saeli, Mara; Perrenet, Jacob; Jochems, Wim M. G.; Zwaneveld, Bert
2011-01-01
The goal of this literature study is to give some preliminary answers to the questions that aim to uncover the Pedagogical Content Knowledge (PCK) of Informatics Education, with focus on Programming. PCK has been defined as the knowledge that allows teachers to transform their knowledge of the subject into something accessible for their students.…
Creating Micro-Videos to Demonstrate Technology Learning and Digital Literacy
ERIC Educational Resources Information Center
Frydenberg, Mark; Andone, Diana
2016-01-01
Purpose: Short videos, also known as micro-videos, have emerged as a platform for sharing ideas, experiences and life events via online social networks. This paper aims to share preliminary results of a study, involving students from two universities who created six-second videos using the Vine mobile app to explain or illustrate technological…
ERIC Educational Resources Information Center
Bedregal, Luis E.; Paris, Manuel Jr.; Anez, Luis M.; Shahar, Golan; Davidson, Larry
2006-01-01
As part of a broader study aimed at evaluating perceived alliance with service providers and level of satisfaction with services received, 103 monolingual Spanish speaking Hispanic women were interviewed. Participants were receiving ongoing behavioral health treatment at three different community service provider sites located in the greater New…
ERIC Educational Resources Information Center
Aherne, Cian; Coughlan, Barry
2017-01-01
Background: Aquatics is an under-researched but possibly appropriate form of activity for people with severe to profound intellectual disabilities (SPIDs). Aim: The current pilot study investigates the suitability of an aquatics programme for service users with SPIDs. Method: Four service users with SPID completed an 8-12-session aquatics…
ERIC Educational Resources Information Center
Sabuncuoglu, Osman; Berkem, Meral
2006-01-01
This study aimed to determine the exact pattern of obsessive--compulsive disorder (OCD) symptoms in children displayed across school and home settings. Twenty-six school children (aged 7 through 17) with OCD were tested using the Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS), the Clinical Global Impression (CGI)--severity subscale and…
ERIC Educational Resources Information Center
Patel, Minal R.; Resnicow, Kenneth; Lang, Ian; Kraus, Kathleen; Heisler, Michele
2018-01-01
Background: Cost-related nonadherence (CRN) to recommended self-management behaviors among adults with chronic conditions such as diabetes is prevalent. Few behavioral interventions to mitigate CRN have been tested and evaluated. Aims: We developed a financial burden resource tool and examined its acceptability and the preliminary effects on…
Learner-Centered Blogging: A Preliminary Investigation of EFL Student Writers' Experience
ERIC Educational Resources Information Center
Lin, Ming Huei
2015-01-01
This study aims to investigate the effectiveness of integrating a learner-centered blogging approach into the EFL writing classroom in Taiwan. For this purpose, a 16-week experiment was conducted, involving an intact class of 18 university-level Taiwanese EFL student writers. During the experiment, the participants first created their own blogs on…
Emergent Writing in Preschoolers: Preliminary Evidence for a Theoretical Framework
ERIC Educational Resources Information Center
Puranik, Cynthia S.; Lonigan, Christopher J.
2014-01-01
Researchers and educators use the term "emergent literacy" to refer to a broad set of skills and attitudes that serve as foundational skills for acquiring success in later reading and writing; however, models of emergent literacy have generally focused on reading and reading-related behaviors. Hence, the primary aim of this study was to…
ERIC Educational Resources Information Center
Marshall, Rebecca Shisler; Laures-Gore, Jacqueline; Love, Kim
2018-01-01
Background: Stroke is currently the leading cause of long-term disability in adults in the United States. There is a need for accessible, low-cost treatments of stroke-related disabilities such as aphasia. Aims: To explore an intervention for aphasia utilizing mindfulness meditation (MM). This preliminary study examines the feasibility of teaching…
ERIC Educational Resources Information Center
Rivers, Kenyatta O.; Perkins, Rosalie A.; Carson, Cecyle P.
2009-01-01
Background: Formal training in dealing with death and dying issues is not a standard content area in communication sciences and disorders programmes' curricula. At the same time, it cannot be presumed that pre-professional students' personal background equips them to deal with these issues. Aim: To investigate the perceptions of pre-professional…
Preliminary Ecotoxicity and Biodegradability Assessment of Metalworking Fluids
NASA Astrophysics Data System (ADS)
Gerulová, Kristína; Amcha, Peter; Filická, Slávka
2010-01-01
The main aim of this study was to evaluate the potential of activated sludge from sewage treatment plant to degrade selected MWFs (ecotoxicity to bacterial consortium) and to evaluate the ecotoxicity by Lemna minor-higher plant. After evaluating the ecotoxicity, biodegradations rate with activated sludge was assessed on the basis of COD measurement. Preliminary study of measuring the ecotoxicity according to OECD 221 by Lemna minor shows effective concentration of Emulzin H at the rate of 81.6 mg l-1, for Ecocool 82.9 mg l-1, for BC 25 about 99.3 mg l-1, and for Dasnobor about 97.3 mg l-1. Preliminary study of measuring the ecotoxicity by bacterial consortium according to OECD 209 (STN EN ISO 8192) shows effective concentration of Blasocut BC 25 at the rate 227.4 mg l-1. According to OECD 302B, the biodegradations level of Emulzin H, Ecocool and BC 25 achieved 80% in 10 days. It can be stated that these MWFs have potential to ultimate degradation, but the statement has to be confirmed by a biodegradability test with other parameters than COD, which exhibits some disadvantages in testing O/W emulsions.
ERIC Educational Resources Information Center
Puranik, Cynthia S.; Patchan, Melissa M.; Lemons, Christopher J.; Al Otaiba, Stephanie
2017-01-01
Despite the poor outcomes for U.S. students on national writing tests, overall research on how to teach writing is sparse, and this scarcity is more pronounced in the early years of beginning to write. In this study 81,200 we present preliminary findings from Year 1 of a 3-year Institute of Education Sciences-funded Goal 2 project aimed at…
Cognitive correlates in panic disorder as related to impulsivity - preliminary report.
Jakuszkowiak-Wojten, Katarzyna; Gałuszko-Węgielnik, Maria; Raczak, Alicja; Cubała, Wiesław Jerzy; Wiglusz, Mariusz Stanisław; Herstowska, Marta; Landowski, Jerzy
2012-09-01
Impulsivity is the neurophysiologically based inability to confirm behaviour to its context or consequences. Overimpulsiveness characterizes many mental disorders and poses an important clinical dilemma. Although the relationship between mood disorders and impulsivity has been well studied the relationship between anxiety and impulsivity is controversial and not well explored. Some studies hypothesise that patients with the diagnosis of panic disorders are characterised by higher levels of impulsivity as a trait as compared to healthy individuals. The aim of this study was to assess cognitive correlates in panic disorder as related to impulsivity measures. Within the preliminary studies four patients diagnosed with panic disorder (DSM-IV-TR) were studied. The severity measure was the Panic and Agoraphobia Scale. The experimental group comprised of psychotropic drug naive patients. Impulsiveness was evaluated with the Barrat Impulsiveness Scale - 11th version (BIS-11). To asses cognitive functions we used CANTAB (Cambridge Neuropsychological Test Automated Battery). BIS-11 scores observed in the group of psychotropic drug naive patients with panic disorder were higher than the adjusted average for the population and correlated with the number of mistakes in CANTAB (Spatial Working Memory Test); rs=0.949; p=0.0513. The preliminary findings indicate a correlation between impulsivity and cognitive deficits in panic disorder in psychotropic drug naive patients.
Vera-Sempere, Francisco; Marzal, Cristina; Pellín-Carcelén, Ana; Martí-Bonmatí, Ezequiel; Bagan, Leticia
2012-01-01
Aim: The aim of this preliminary study was to detect cytological changes in the oral mucosa after using a mouth wash with alcohol. Material and Methods: A prospective double-blind, controlled study was performed, for 6 months. Group 1 consisted of 30 subjects who used a mouth rinse with 26.9% of alcohol [Listerine®] and Group 2 consisted of 30 subjects who used a mouth rinse with the same ingredients but with no alcohol. We obtained three cytological samples from the oral mucosa. The presence of cytological atypia, binucleation and karyorrhesis, and type of cells were studied. We also used a fluorescent in situ hybridization technique (FISH) in 15 samples in each group, for the micronucleus. Results: We found no clinical mucosal alteration after using the mouth wash at the end of the study in either group. We observed no cytological differences between the groups at the end of the study (p>0.05). Regarding the study of the micronucleus by FISH, we observed no significant difference between the groups (p>0.05). Conclusions: Our results showed no cytological alteration in patients using a mouth rinse with alcohol, but these findings should be considered preliminary results, to be confirmed in a greater sample of patients. Key words:Mouth wash, oral mucosa, cytological change, alcohol. PMID:23085712
Clerici, P; Guercio, A
2010-01-01
The proposed model is aimed at assessing work-related stress and consists of a preliminary phase during which the Organization is monitored, Indexes and stressors are defined, characterized and then weighted; existing symptoms (if any) are also identified. A 'Probability vs. Severity' Matrix is then built up as a result: these tasks can profitably be performed by a technical professional, typically the Responsible of the Safety and Health Committee. According to found evidences, a second phase, strictly based upon the application of psychosocial research tools, might be needed to investigate group of workers that resulted troublesome during the preliminary phase. The preliminary phase of investigation on organizational stressors and indexes can be easily and successfully integrated with the 'Safety Assessment' steps provided for the B-BS protocol, also aimed at monitoring the organizational wellbeing and consequently acting on the workers' behavior. The model has been specifically designed for Small and Medium Enterprises, with the global objective of preventing accidents at work due to misbehavior and distraction, by correctly and safely applying operational procedures and mutual relationships.
Preliminary Study of OCD and Health Disparities at the U.S.-Mexico Border
Olson, Tom; Vera, Beatriz; Perez, Oriana
2007-01-01
The widespread and devastating nature of obsessive compulsive disorder (OCD) sharply contrasts with the paucity of research involving Mexican Americans and Mexicans who suffer from this condition. This mixed-methods preliminary study was intended to provide initial data and to pilot the procedures for a larger investigation of the cultural identification, symptomatology, health concerns, coping mechanisms, and quality of life of Mexican Americans and Mexicans with OCD living in the U.S.-Mexico border region of El Paso, Texas and Ciudad Juarez, Mexico. For the sample of six participants, whose symptoms ranged from moderate to extreme, OCD was associated with marked impairment in quality of life, particularly in terms of social functioning, an area of central importance for many Mexican Americans and Mexicans. Areas of further study were identified, with the aim of developing culturally sensitive interventions to decrease health disparities involving OCD. PMID:17917689
Mercury exposure on potential plant Ludwigia octovalvis L. - Preliminary toxicological testing
NASA Astrophysics Data System (ADS)
Alrawiq, Huda S. M.; Mushrifah, I.
2013-11-01
The preliminary test in phytoremediation is necessaryto determine the ability of plant to survive in media with different concentrations of contaminant. It was conducted to determine the maximum concentration of the contaminant that isharmful to the plant and suppress the plant growth. This study showed the ability of Ludwigia octovalvisto resist mercury (Hg) contaminant in sand containing different concentrations of Hg (0, 0.5, 1, 2, 4, 6 and 8 mg/L). The experimental work wasperformed under greenhouse conditions for an observation period of 4 weeks. Throughout the 4 weeks duration, the resultsshowed that 66.66% of the plants withered for on exposure to Hg concentration of 4 mg/L and 100% withered at higher concentrations of 6 and 8 mg/L. The results of this study may serve as a basis for research that aims to study uptake and accumulation of Hg using potential phytoremediation plants.
ODA, Hitomi; MORI, Akihiro; LEE, Peter; SAEKI, Kaori; ARAI, Toshiro; SAKO, Toshinori
2014-01-01
ABSTRACT Sitagliptin is a dipeptidyl peptidase-4 inhibitor aimed at treating Type 2 diabetes mellitus (T2DM) and T1DM, by increasing blood levels of Glucagon-like peptide 1 (GLP-1) and insulin. The objective of this preliminary study is to characterize Sitagliptin’s ability for glycemic control, in healthy dogs under an oral glucose tolerance test (OGTT) environment. Overall, Sitagliptin did not result in any significant changes to temporal glucose and insulin concentrations. However, a ~55% increase in median total GLP-1 AUC0–120min was observed, as compared to baseline control in healthy dogs (n=5), thus indicating a similar mode of action of Sitagliptin between healthy dogs and humans. Future studies to validate the use of Sitagliptin with dogs suffering from insulin independent diabetes are warranted. PMID:24931645
NASA Astrophysics Data System (ADS)
Koenig, Karsten; Schneckenburger, Herbert
1994-09-01
The laser-induced in vivo autofluorescence of human teeth was investigated by means of time- resolved/time-gated fluorescence techniques. The aim of these studies was non-contact caries and plaque detection. Carious lesions and dental plaque fluoresce in the red spectral region. This autofluorescence seems to be based on porphyrin-producing bacteria. We report on preliminary studies on patients using a novel method of autofluorescence imaging. A special device was constructed for time-gated video imaging. Nanosecond laser pulses for fluorescence excitation were provided by a frequency-doubled, Q-switched Nd:YAG laser. Autofluorescence was detected in an appropriate nanosecond time window using a video camera with a time-gated image intensifier (minimal time gate: 5 ns). Laser-induced autofluorescence based on porphyrin-producing bacteria seems to be an appropriate tool for detecting dental lesions and for creating `caries-images' and `dental plaque' images.
Skucha-Nowak, Małgorzata; Machorowska-Pieniążek, Agnieszka; Tanasiewicz, Marta
2016-01-01
The aim of the infiltration technique is to penetrate demineralized enamel with a low viscosity resin. Icon® (DMG) is the first ever and so far the only dental infiltrant. Bacteriostaticity is one of the properties that should be inherent in dental infiltrants, but Icon lacks this feature. The aim of the preliminary study was to properly choose a dye which would allow us to assess the penetrating abilities of our own, experimental preparation with features of a dental infiltrant with bacteriostatic properties and to compare using an optical microscope the depth of infiltration of the designed experimental preparation with the infiltrant available on the market. The preparation is supposed to infiltrate decalcified human enamel and be assessed with an optical microscope. Eosin, neutral fuchsine and methylene blue were added to experimental preparation with dental infiltrant features and to Icon® (DMG) in order to assess the depth of penetration of the experimental solution into the decalcified layers of enamel. The experimental solution mixes well with eosin, neutral fuchsine, and methylene blue. During the preliminary study, the authors concluded that the experimental solution mixes well with methylene blue, neutral fuchsine, and eosin. An addition of eosin to a preparation which infiltrates inner, demineralized enamel layers, facilitates the assessment of such a preparation with an optical microscope. A designed experimental solution with the main ingredients, i.e., 2-hydroxyethyl methacrylate (HEMA) and tetraethylene glycol dimethacrylate (TEGDMA) with a ratio of 75% to 25% penetrates the demineralized (decalcified) inner parts of the enamel and polymerizes when exposed to light. In order to assess the infiltration of the experimental solution into the demineralized enamel layers, it is required to improve the measurement techniques that utilize optical microscopy.
ERIC Educational Resources Information Center
Back, Christina; Gustafsson, Per A.; Larsson, IngBeth; Bertero, Carina
2011-01-01
Objective: The aim of this study was to describe how sexually abused children experience the legal process, a process that includes being questioned by the police during the preliminary investigation and by lawyers and the prosecutor in the courtroom, and meeting other professionals from various agencies. Method: Face-to-face in-depth interviews…
ERIC Educational Resources Information Center
Stumbo, Norma J.; Hedrick, Bradley N.; Weisman, Courtney; Martin, Jay K.
2011-01-01
The purpose of this preliminary study was to explore the residual barriers and facilitators for a selected group of individuals with severe physical disabilities who had been afforded a comprehensive set of strategies and services aimed at meeting their basic personal as well as academic needs. Their perceptions of both barriers and facilitators,…
ERIC Educational Resources Information Center
Wilksch, Simon M.; Durbridge, Mitchell R.; Wade, Tracey D.
2008-01-01
The study aims to find out whether programs targeting perfectionism and media literacy are more effective than control classes in reducing eating disorder risk factors. Finding reveals that perfectionism programs are well suited to individuals of mid- to late adolescent age and shows the importune of making prevention programs developmentally…
Children with Speech, Language and Communication Needs: Their Perceptions of Their Quality of Life
ERIC Educational Resources Information Center
Markham, Chris; van Laar, Darren; Gibbard, Deborah; Dean, Taraneh
2009-01-01
Background: This study is part of a programme of research aiming to develop a quantitative measure of quality of life for children with communication needs. It builds on the preliminary findings of Markham and Dean (2006), which described some of the perception's parents and carers of children with speech language and communication needs had…
ERIC Educational Resources Information Center
Rawles, Joanna
2016-01-01
The aims of this article are twofold: to discuss the value of practice-based research as a basis for enhancing learning and teaching in social work and, as an illustration of this, to present the findings of a preliminary qualitative research study into social work students' development of professional judgment skills. The research was conducted…
ERIC Educational Resources Information Center
Lingam, Govinda; Lingam, Narsamma; Sharma, Lalesh
2017-01-01
This preliminary study reports on educational changes and its impact on primary teachers' world of work in Fiji. Data were gathered from 38 primary teachers, using a questionnaire of Likert scale items and open-ended questions aiming to identify the intensity of the changes that have occurred in their work. The data analysis reveals the…
ERIC Educational Resources Information Center
Goetz, William Clark
2013-01-01
Rural Kentucky residents suffer twice as many fire residential deaths than the national average. Fire prevention programs are primarily aimed at elementary school children however these children do not make the decisions nor take the precautions necessary to alter these conditions; their adult parents do. There is little research into the…
Cognition and Lobar Morphology in Full Mutation Boys with Fragile X Syndrome
ERIC Educational Resources Information Center
Meguid, Nagwa A.; Fahim, Cherine; Sami, Rasha; Nashaat, Neveen H.; Yoon, Uicheul; Anwar, Mona; El-Dessouky, Hosam M.; Shahine, Elham A.; Ibrahim, Ahmed Samir; Mancini-Marie, Adham; Evans, Alan C.
2012-01-01
The aims of the present study are twofold: (1) to examine cortical morphology (CM) associated with alterations in cognition in fragile X syndrome (FXS); (2) to characterize the CM profile of FXS versus FXS with an autism diagnosis (FXS+Aut) as a preliminary attempt to further elucidate the behavioral distinctions between the two sub-groups. We…
Measuring attitudes towards suicide: Preliminary evaluation of an attitude towards suicide scale.
Cwik, Jan Christopher; Till, Benedikt; Bieda, Angela; Blackwell, Simon E; Walter, Carolin; Teismann, Tobias
2017-01-01
Our study aimed to validate a previously published scale assessing attitudes towards suicide. Factor structure, convergent and discriminant validity, and predictive validity were investigated. Adult German participants (N=503; mean age=24.74years; age range=18-67years) anonymously completed a set of questionnaires. An exploratory factor analysis was conducted, and incongruous items were deleted. Subsequently, scale properties of the reduced scale and its construct validity were analyzed. A confirmatory factor analysis was then conducted in an independent sample (N=266; mean age=28.77years; age range=18-88years) to further confirm the factor structure of the questionnaire. Parallel analysis indicated a three-factor solution, which was also supported by confirmatory factor analysis: right to commit suicide, interpersonal gesture and resilience. The subscales demonstrated acceptable construct and discriminant validity. Cronbach's α for the subscales ranged from 0.67 to 0.83, explaining 49.70% of the total variance. Positive attitudes towards suicide proved to be predictive of suicide risk status, providing preliminary evidence for the utility of the scale. Future studies aiming to reproduce the factor structure in a more heterogeneous sample are warranted. Copyright © 2016 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Gogoladze, Z.; Moscatelli, M.; Giallini, S.; Avalle, A.; Gventsadze, A.; Kvavadze, N.; Tsereteli, N.
2016-12-01
Seismic risk is a crucial issue for South Caucasus, which is the main gateway between Asia and Europe. The goal of this work is to propose new methods and criteria for defining an overall approach aimed at assessing and mitigating seismic risk in Georgia. In this reguard seismic microzonation represents a highly useful tool for seismic risk assessmentin land management, for design of buildings or structures and for emergency planning.Seismic microzonation assessment of local seismic hazard,which is a component of seismicity resulting from specific local characteristics which cause local amplification and soil instability, through identification of zones with seismically homogeneous behavior. This paper presents the results of preliminary study of seismic microzonation of Gori, Georgia. Gori is and is located in the Shida Kartli region and on both sides of Liachvi and Mtkvari rivers, with area of about 135 km2around the Gori fortress. Gori is located in Achara-Trialeti fold-thrust belt, that is tectonically unstable. Half of all earthquakes in Gori area with magnitude M≥3.5 have happened along this fault zone and on basis of damage caused by previous earthquakes, this territory show the highest level of risk (the maximum value of direct losses) in central part of the town. The seismic microzonation map of level 1 for Gori was carried out using: 1) Already available data (i.e., topographic map and boreholes data), 2) Results of new geological surveys and 3) Geophysical measurements (i.e., MASW and noise measurements processed with HVSR technique). Our preliminary results highlight the presence of both stable zones susceptible to local amplifications and unstable zones susceptible to geological instability. Our results are directed to establish set of actions aimed at risk mitigation before initial onset of emergency, and to management of the emergency once the seismic event has occurred. The products obtained, will contain the basic elements of an integrated system aimed at reducing risk and improving over all safety of people and infrastructure in Georgia.
A study of ignition phenomena of bulk metals by radiant heating
NASA Technical Reports Server (NTRS)
Branch, Melvin C.; Abbud-Madrid, A.; Feiereisen, T. J.; Daily, J. W.
1993-01-01
Early research on combustion of metals was motivated by the knowledge of the large heat release and corresponding high temperatures associated with metal-oxygen reactions. The advent of space flight brought about an increased interest in the ignition and combustion of metallic particles as additives in solid rocket propellants. More recently, attention has been given to the flammability properties of bulk, structural metals due to the number of accidental explosions of metal components in high-pressure oxygen systems. The following work represents a preliminary study that is part of a broader research effort aimed at providing further insight into the phenomena of bulk metal combustion by looking at the effects of gravity on the ignition behavior of metals. The scope of this preliminary experimental study includes the use of a non-coherent, continuous radiation ignition source, the measurement of temperature profiles of a variety of metals and a qualitative observation of the ignition phenomena at normal gravity. The specific objectives of the investigation include: (1) a feasibility study of the use of a continuous radiation source for metal ignition; (2) testing and characterization of the ignition behavior of a variety of metals; and (3) building a preliminary experimental database on ignition of metals under normal gravity conditions.
Multi-path transportation futures study: Results from Phase 1
DOE Office of Scientific and Technical Information (OSTI.GOV)
Patterson, Phil; Singh, Margaret; Plotkin, Steve
2007-03-09
This PowerPoint briefing provides documentation and details for Phase 1 of the Multi-Path Transportation Futures Study, which compares alternative ways to make significant reductions in oil use and carbon emissions from U.S. light vehicles to 2050. Phase I, completed in 2006, was a scoping study, aimed at identifying key analytic issues and constructing a study design. The Phase 1 analysis included an evaluation of several pathways and scenarios; however, these analyses were limited in number and scope and were designed to be preliminary.
Mazzoleni, Stefano; Turchetti, Giuseppe; Palla, Ilaria; Posteraro, Federico; Dario, Paolo
2014-09-01
During the last decade, different robotic devices have been developed for motor rehabilitation of stroke survivors. These devices have been shown to improve motor impairment and contribute to the understanding of mechanisms underlying motor recovery after a stroke. The assessment of the robotic technology for rehabilitation assumes great importance. The aim of this study is to present preliminary results on the assessment of the acceptability of the robotic technology for rehabilitation on a group of thirty-four chronic stroke patients. The results from questionnaires on the patients' acceptability of two different robot-assisted rehabilitation scenarios show that the robotic approach was well accepted and tolerated by the patients. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.
ERIC Educational Resources Information Center
Lariscy, Ruthann; Reber, Bryan; Paek, Hye-Jin
2011-01-01
The aims of this study are to identify health concerns and behaviors, to understand why some concerns are more worrisome than others, and to learn what information sources are relied on for a young age cohort--7th grade students--in two poor and near-poor school districts. Focus groups--one each of girls and boys--in each of two public school…
ERIC Educational Resources Information Center
McDougall, Janette; Servais, Michelle; Meyer, Katherine; Case, Sheila; Dannenhold, Kara; Johnson, Sue; Riggin, Colleen
2009-01-01
This is a preliminary evaluation of a program aimed at providing training, consultation, and resource materials to educators in public schools in order to build the capacity of those educators and schools to meet the needs of students with autism spectrum disorders. Educator and school level outcomes were evaluated and information about program…
Markova, Nadezhda V.; Batovska, Daniela I.; Kozuharova, Ekaterina K.; Enchev, Venelin G.
2015-01-01
Aim: The parent of xGraptoveria, Graptopetalum paraguayense, is used in Chinese folk medicine for alleviating hepatic disorders, detumescence and detoxication, lowering of blood pressure, inhibition of cancer cells, exerting diuretic effects, relieving pain and infections. No data are available regarding its anti-conjunctivitis effect. The aim of this preliminary study is to test the anti-conjunctivitis properties of xGraptoveria (Crassulaceae) and to identify its bioactive constituents. Materials and Methods: Fresh watery juice of leaves of xGraptoveria was extracted with n-butanol and the extract was analyzed using gas chromatography-mass spectrometry (GC/MS). The ethnobotanical appraisal of the anti-conjunctivitis properties of xGraptoveria was based on 11 interviews about the symptoms against which this plant demonstrated positive effect. Results: Fresh juice of xGraptoveria leaves applied directly to the irritated eye 2 times per day cured conjunctivitis in all reported cases. The main groups of organic compounds identified by GC/MS analysis in the fresh extracted leaf juice of xGraptoveria were: Alkylamines, hydroxycarboxylic acids, aliphatic and aromatic carboxylic acids, amino acids, alcohols, aromatic and aliphatic hydrocarbons. Conclusion: In this preliminary study, it is suggested that xGraptoveria exerts anti-conjunctivitis activity, through synergistic effect of different chemical compounds, most probably alkylamines and mainly hydroxycarboxylic, aliphatic, and aromatic carboxylic acids. PMID:26401380
2017-03-01
breathing capacity (Aim 1) and forelimb function (Aim 2), without systemic hypertension or hippocampal pathology (Aim 3). SPECIFIC AIMS Aim 1 (Florida...benefits. On the other hand, there was no evidence for pathology ( hypertension or hippocampal pathology). We were not able to perform time-series... hypertension or hippocampal (CA1) pathology. However, we did see striking (and surprising) preliminary evidence that prolonged rAIH: 1) reduced volume of the
NASA Astrophysics Data System (ADS)
Palmiste, Ü.; Voll, H.
2017-10-01
The development of advanced air cleaning technologies aims to reduce building energy consumption by reduction of outdoor air flow rates while keeping the indoor air quality at an acceptable level by air cleaning. Photocatalytic oxidation is an emerging technology for gas-phase air cleaning that can be applied in a standalone unit or a subsystem of a building mechanical ventilation system. Quantitative information on photocatalytic reactor performance is required to evaluate the technical and economic viability of the advanced air cleaning by PCO technology as an energy conservation measure in a building air conditioning system. Photocatalytic reactors applying optical fibers as light guide or photocatalyst coating support have been reported as an approach to address the current light utilization problems and thus, improve the overall efficiency. The aim of the paper is to present a preliminary evaluation on continuous flow optical fiber photocatalytic reactors based on performance indicators commonly applied for air cleaners. Based on experimental data, monolith-type optical fiber reactor performance surpasses annular-type optical fiber reactors in single-pass removal efficiency, clean air delivery rate and operating cost efficiency.
PLA and two components silicon rubber blends aiming for frozen foods packaging applications
NASA Astrophysics Data System (ADS)
Meekum, Utai; Khiansanoi, Apichart
2018-03-01
Designing of PLA and two components silicone rubber blends was studies. Frozen food packaging application is the main ultimate aim. The statistical method using 23 DOE was conducted. The standard testing methods, in particular impact testing at sub-zero temperature, were performed. The preliminary blend formula comprised 1.0 phr of silane and polyester polyols, respectively, was initially resolved. Then, the optimize the silicone portion in the blends was determined. Blending formula using 8.0 phr of silicone with respect to PLA matrix gave rise to the overall satisfactory properties. 3. TETA was used as the silicone curing agent and reactively blended onto the ingredients. TETA at 0.4 phr, with respect to the silicone, enhanced the mechanical properties, especially flexibility and toughness, of the PLA/silicone blend. Exceeding the optimal TETA loading would cause the chain scission and also the dilution effects. Hence, marginal inferior properties of the blends were be experienced. The preliminary biodegradability investigation found that the PLA/silicone blend initially triggered at the second week. Its degradation rate was likely to be faster than neat PLA.
Berlin, Lisa J; Martoccio, Tiffany L; Appleyard Carmody, Karen; Goodman, W Benjamin; O'Donnell, Karen; Williams, Janis; Murphy, Robert A; Dodge, Kenneth A
2017-12-01
US government-funded early home visiting services are expanding significantly. The most widely implemented home visiting models target at-risk new mothers and their infants. Such home visiting programs typically aim to support infant-parent relationships; yet, such programs' effects on infant attachment quality per se are as yet untested. Given these programs' aims, and the crucial role of early attachments in human development, it is important to understand attachment processes in home visited families. The current, preliminary study examined 94 high-risk mother-infant dyads participating in a randomized evaluation of the Healthy Families Durham (HFD) home visiting program. We tested (a) infant attachment security and disorganization as predictors of toddler behavior problems and (b) program effects on attachment security and disorganization. We found that (a) infant attachment disorganization (but not security) predicted toddler behavior problems and (b) participation in HFD did not significantly affect infant attachment security or disorganization. Findings are discussed in terms of the potential for attachment-specific interventions to enhance the typical array of home visiting services.
ERIC Educational Resources Information Center
Lopez, Beatriz; Leekam, Susan R.; Arts, Gerda R. J.
2008-01-01
This study aimed to test the assumption drawn from weak central coherence theory that a central cognitive mechanism is responsible for integrating information at both conceptual and perceptual levels. A visual semantic memory task and a face recognition task measuring use of holistic information were administered to 15 children with autism and 16…
NASA Technical Reports Server (NTRS)
Mancini, D.; Bussoletti, E.; Mennella, V.; Vittone, A. A.; Colangeli, L.; Mirra, C.; Stephens, J.; Nuth, J.; Lilleleht, L.; Furgeson, F.
1992-01-01
The first results of the STARDUST project, aimed at producing and analyzing cosmic-dust analog materials in microgravity conditions, are summarized. The discussion covers the purpose of the investigation, cosmic-dust formation and properties, previous simulations of cosmic-dust formation, the current approach, the microgravity experimental apparatus, and potential advantages of studying dust formation under microgravity conditions.
ERIC Educational Resources Information Center
Powell, Lesley; Cheshire, Anna
2010-01-01
The aim of this study was to conduct a pilot evaluation of the Mosac Massage Program, a novel program that uses massage to address some of the difficulties faced by children who have been sexually abused and their nonabusing parents. Interviews were conducted with four participating mothers immediately before and after the program. Benefits…
ERIC Educational Resources Information Center
Bullock, Bob; And Others
This minicourse was prepared for use with secondary physics students in the Dallas Independent School District and is one option in a physics program which provides for the selection of topics on the basis of student career needs and interests. This minicourse was aimed at two levels in the study of basic machines. The "light" level…
ERIC Educational Resources Information Center
Deng, Meng; Wang, Sisi; Guan, Wenjun; Wang, Yan
2017-01-01
The aim of this study was to develop and validate an instrument of inclusive teachers' competencies for teaching students with special educational needs in China. Data were obtained from a preliminary and large-scale investigation in Beijing. The primary analyses included exploratory factor analysis and confirmatory factor analysis. The findings…
ERIC Educational Resources Information Center
Lin, Jin-Ding; Sung, Chang-Lin; Lin, Lan-Ping; Liu, Ta-Wen; Lin, Pei-Ying; Chen, Li-Mei; Chu, Cordia M.; Wu, Jia-Ling
2010-01-01
This study aims to establish evidence-based data to explore the perceptions and experience of primary care physicians in the Pap smear screening provision for women with intellectual disabilities (ID), and to analyze the associated factors in the delivery of screening services to women with ID in Taiwan. Data obtained by a cross-sectional survey…
ERIC Educational Resources Information Center
Barratt-Pugh, Llandis
This paper outlines the background and preliminary findings of a study currently in progress in Perth, Western Australia, to investigate the relationship between competence based training and the development of lifelong learning skills. The paper explores both the underlying aims of competency-based training (CBT) and the educational antecedents…
ERIC Educational Resources Information Center
Laghi, Fiorenzo; Lonigro, Antonia; Baiocco, Roberto; Baumgartner, Emma
2013-01-01
As adolescents' alcohol abuse is more widespread almost everywhere, the aim of this study was to better understand the influence of both alcohol expectancies and parenting styles on this risky behaviour in order to allow the development of future prevention programmes, by evaluating the correlation between these variables. A total of 1500 subjects…
ERIC Educational Resources Information Center
Coholic, Diana; Eys, Mark; Lougheed, Sean
2012-01-01
We discuss preliminary findings from a study that investigated the effectiveness of a Holistic Arts-Based Group Program (HAP) for the development of resilience in children in need. The HAP teaches mindfulness using arts-based methods, and aims to teach children how to understand their feelings and develop their strengths. We assessed the…
ERIC Educational Resources Information Center
deVille, Barry, Ed.
This is a preliminary examination of the present status and future prospects of educational technology in Nova Scotian schools. It is aimed at developing a plan to enhance the quality of educational technology by concentrating on systems which will be conducive to realizing educational goals at a reasonable cost. An overview of the institutional…
Cabasse, C; Marie-Cousin, A; Huet, A; Sixou, J L
2015-03-01
Anesthetizing MIH (Molar and Incisor Hypomineralisation) teeth is one of the major challenges in paediatric dentistry. Computer-assisted IO injection (CAIO) of 4% articaine with 1:200,000 epinephrine (Alphacaine, Septodont) has been shown to be an efficient way to anesthetize teeth in children. The aim of this study was to assess the efficacy of this method with MIH teeth. This preliminary study was performed using the Quick Sleeper system (Dental Hi Tec, Cholet, France) that allows computer-controlled rotation of the needle to penetrate the bone and computer-controlled injection of the anaesthetic solution. Patients (39) of the department of Paediatric Dentistry were included allowing 46 sessions (including 32 mandibular first permanent molars) to be assessed. CAIO showed efficacy in 93.5% (43/46) of cases. Failures (3) were due to impossibility to reach the spongy bone (1) and to achieve anaesthesia (2). This prospective study confirms that CAIO anaesthesia is a promising method to anesthetize teeth with MIH that could therefore be routinely used by trained practitioners.
Cassin, Stephanie E.; Wnuk, Susan; Du, Chau; Jackson, Timothy; Hawa, Raed; Parikh, Sagar V.
2017-01-01
Objective This study aimed to determine the feasibility and preliminary efficacy of a post-operative telephone-based cognitive behavioral therapy intervention (Tele-CBT) in improving eating pathology and psychosocial functioning. Methods Six-month post-operative bariatric surgery patients (n = 19) received six sessions of Tele-CBT. Study outcome variables included binge eating (BES), emotional eating (EES), depressive symptoms (PHQ-9), and anxiety symptoms (GAD-7). Results Retention was 73.7 % post-intervention. Tele-CBT resulted in significant reductions in mean difference scores on BES, EES-Total, EES-Anxiety, EES-Anger, PHQ9, and GAD7. Tele-CBT patients experienced a mean weight loss of 8.62 ± 15.02 kg between 6-months post-surgery (pre-Tele-CBT) and 12-months post-surgery. Conclusions These preliminary results suggest that post-surgery Tele-CBT is feasible and can improve post-surgery symptoms of psychopathology in this uncontrolled study, supporting the need for a randomized controlled trial. PMID:27491293
Yee, Kwang Chien; Wong, Ming Chao; Turner, Paul
2017-01-01
Stimulating sustained behavioural change through information and technology has been an aim of much health informatics research. Traditional approaches use technology to mediate communications between health professionals and patients. More recent lifestyle technologies engage the patient directly with information and advice - but what of the phenomena that is Pokémon Go - does it point to another way of achieving health benefits through fun? This paper aims to explore some of the conceptual questions for health informatics stimulated by the phenomenal popularity of Pokémon Go. The paper is grounded analysis of data generated through a preliminary participatory observational study in Australia.
Shepard, Michele; Brenner, Sara
2014-01-01
Numerous studies are ongoing in the fields of nanotoxicology and exposure science; however, gaps remain in identifying and evaluating potential exposures from skin contact with engineered nanoparticles in occupational settings. The aim of this study was to identify potential cutaneous exposure scenarios at a workplace using engineered nanoparticles (alumina, ceria, amorphous silica) and evaluate the presence of these materials on workplace surfaces. Process review, workplace observations, and preliminary surface sampling were conducted using microvacuum and wipe sample collection methods and transmission electron microscopy with elemental analysis. Exposure scenarios were identified with potential for incidental contact. Nanoparticles of silica or silica and/or alumina agglomerates (or aggregates) were identified in surface samples from work areas where engineered nanoparticles were used or handled. Additional data are needed to evaluate occupational exposures from skin contact with engineered nanoparticles; precautionary measures should be used to minimize potential cutaneous exposures in the workplace.
Exotic nuclear studies around and below A = 100
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nara Singh, B. S.; Wadsworth, R.; Brock, T. S.
2011-11-30
A RISING experiment with an aim to study exotic Cd nuclei was carried out at GSI-FRS facility. Some preliminary results from this experiment are presented here. In particular, the {beta} decay of {sup 96}Cd to {sup 96}Ag revealed the existence of a high spin isomer predicted a few decades ago. In this context, the structures of both these nuclei are discussed. Shell model calculations using the Gross-Frenkel interaction are used to interpret the results.
Perlis, Michael; Grandner, Michael; Zee, Jarcy; Bremer, Erin; Whinnery, Julia; Barilla, Holly; Andalia, Priscilla; Gehrman, Phil; Morales, Knashawn; Thase, Michael; Bootzin, Richard; Ader, Robert
2015-01-01
Background and aim At present, there is no consensus regarding how to medically manage chronic insomnia in the long term. The unstated standard of practice is for patients to use hypnotics intermittently. The present study aimed to compare a partial reinforcement strategy with nightly and intermittent dosing strategies for its potential as a maintenance therapy. Methods A mixed model was used in the study. One between-subjects factor: group (n = 4). One repeated-measures factor: time (12 weekly assessments). A total of 74 subjects with chronic Insomnia were treated with 10 mg zolpidem for 4 weeks. Treatment respondents were randomized to nightly dosing with 10 mg or 5 mg (QHS-10 and QHS-5), intermittent dosing with 10 mg (IDS-10 [3–5 days weekly]), or partial reinforcement dosing with 10 mg (PRS-10 [nightly pill use with 50% active medication and 50% placebos]) for 12 weeks. Results It was found, in compliant subjects (n = 55), that all four strategies evaluated maintained treatment response over time (ie, prevented or delayed relapse). For the subjects that remained in remission, the subjects in the intermittent dosing group (IDS-10) group exhibited poorer sleep continuity. Conclusions While best considered a preliminary study, the present findings suggest that the partial reinforcement strategy may be a viable means toward maintaining treatment gains over time with less active medication. PMID:26298795
Sewage sludge drying by energy recovery from OFMSW composting: Preliminary feasibility evaluation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rada, Elena Cristina; Ragazzi, Marco; Villotti, Stefano
2014-05-01
Highlights: • The aim is to support the drying of sewage sludge, using a solar greenhouse. • The system allows the exploitation of heat available from OFMSW aerobic process. • Another aim is to face the problem of OFMSW treatment, in particular food waste. • Energy and mass balances are presented for a case study. - Abstract: In this paper an original energy recovery method from composting is analyzed. The integrated system exploits the heat available from the aerobic biochemical process in order to support the drying of sewage sludge, using a specific solar greenhouse. The aim is to tacklemore » the problem of organic waste treatment, with specific regard to food waste. This is done by optimizing the energy consumption of the aerobic process of composting, using the heat produced to solve a second important waste management problem such as the sewage waste treatment. Energy and mass balances are presented in a preliminary feasibility study. Referring to a composting plant with a capacity of 15,000 t/y of food waste, the estimation of the power from recovered heat for the entire plant resulted about 42 kW. The results demonstrated that the energy recoverable can cover part of the heat necessary for the treatment of sludge generated by the population served by the composting plant (in terms of food waste and green waste collection). The addition of a renewable source such as solar energy could cover the residual energy demand. The approach is presented in detail in order for it to be replicated in other case studies or at full scale applications.« less
Andrade, E L; Bento, A F; Cavalli, J; Oliveira, S K; Schwanke, R C; Siqueira, J M; Freitas, C S; Marcon, R; Calixto, J B
2016-12-12
The process of drug development involves non-clinical and clinical studies. Non-clinical studies are conducted using different protocols including animal studies, which mostly follow the Good Laboratory Practice (GLP) regulations. During the early pre-clinical development process, also known as Go/No-Go decision, a drug candidate needs to pass through several steps, such as determination of drug availability (studies on pharmacokinetics), absorption, distribution, metabolism and elimination (ADME) and preliminary studies that aim to investigate the candidate safety including genotoxicity, mutagenicity, safety pharmacology and general toxicology. These preliminary studies generally do not need to comply with GLP regulations. These studies aim at investigating the drug safety to obtain the first information about its tolerability in different systems that are relevant for further decisions. There are, however, other studies that should be performed according to GLP standards and are mandatory for the safe exposure to humans, such as repeated dose toxicity, genotoxicity and safety pharmacology. These studies must be conducted before the Investigational New Drug (IND) application. The package of non-clinical studies should cover all information needed for the safe transposition of drugs from animals to humans, generally based on the non-observed adverse effect level (NOAEL) obtained from general toxicity studies. After IND approval, other GLP experiments for the evaluation of chronic toxicity, reproductive and developmental toxicity, carcinogenicity and genotoxicity, are carried out during the clinical phase of development. However, the necessity of performing such studies depends on the new drug clinical application purpose.
Brady, Pamela; Kangas, Maria; McGill, Katherine
2017-04-01
The first aim of this systematic review was to evaluate the evidence for family psychoeducation (FPE) interventions for major depressive disorder (MDD). A second aim was to compare the efficacy of different modes of delivering face-to-face FPE interventions. Ten studies (based on nine distinct samples) were identified comprising four single-family studies, four multifamily studies, one single versus multifamily comparative study, and one peer-led, mixed-diagnosis study. Seven studies measured patient functioning and six reported positive outcomes. Six studies measured carer's well-being and four reported positive outcomes. Results provide preliminary evidence that FPE leads to improved outcomes for patient functioning and family-carer's well-being for persons with depression. The implications for future development and delivery of FPE interventions for MDD are discussed. © 2016 American Association for Marriage and Family Therapy.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mitchell, M.; Nam, H; Carter, A
2009-01-01
Adeno-associated virus (AAV) serotype 9, which is under development for gene-delivery applications, shows significantly enhanced capsid-associated transduction efficiency in muscle compared with other AAV serotypes. With the aim of characterizing the structural determinants of this property, the purification, crystallization and preliminary X-ray crystallographic analyses of the AAV9 viral capsid are reported. The crystals diffracted X-rays to 2.8 A resolution using synchrotron radiation and belonged to the trigonal space group P32, with unit-cell parameters a = b = 251.0, c = 640.0 A. There are three complete viral capsids in the crystal unit cell. The orientation and position of the asymmetricmore » unit capsid have been determined by molecular-replacement methods and structure determination is in progress.« less
NASA Astrophysics Data System (ADS)
Hasan, Noor Haliza; Abdullah, M. T.
2008-01-01
The aim of the study is to use cluster analysis on morphometric parameters within the genus Kerivoula to produce a dendrogram and to determine the suitability of this method to describe the relationship among species within this genus. A total of 15 adult male individuals from genus Kerivoula taken from sampling trips around Borneo and specimens kept at the zoological museum of Universiti Malaysia Sarawak were examined. A total of 27 characters using dental, skull and external body measurements were recorded. Clustering analysis illustrated the grouping and morphometric relationships between the species of this genus. It has clearly separated each species from each other despite the overlapping of measurements of some species within the genus. Cluster analysis provides an alternative approach to make a preliminary identification of a species.
Merlo, Lisa J.; Stone, Amanda M.; Bibbey, Alex
2013-01-01
This study aimed to develop and assess the psychometric properties of an English language measure of problematic mobile phone use. Participants were recruited from a university campus, health science center, and other public locations. The sample included 244 individuals (68.4% female) aged 18–75. Results supported a unidimensional factor structure for the 20-item self-report Problematic Use of Mobile Phones (PUMP) Scale. Internal consistency was excellent (α = 0.94). Strong correlations (r = .76, P < .001) were found between the PUMP Scale and an existing scale of cellular phone dependency that was validated in Asia, as well as items assessing frequency and intensity of mobile phone use. Results provide preliminary support for the use of the PUMP Scale to measure problematic use of mobile phones. PMID:24826371
Integrating "GeoGebra" into IWB-Equipped Teaching Environments: Preliminary Results
ERIC Educational Resources Information Center
Lavicza, Zsolt; Papp-Varga, Zsuzsanna
2010-01-01
The aims of the project described in this paper are threefold. Firstly, the authors aim to examine how "GeoGebra", an open-source dynamic mathematics software application, can be used successfully for mathematics teaching in interactive whiteboard (IWB)-equipped teaching environments. Secondly, they intend to uncover how professional…
The cost of child health inequalities in Aotearoa New Zealand: a preliminary scoping study
2012-01-01
Background Health inequalities have been extensively documented, internationally and in New Zealand. The cost of reducing health inequities is often perceived as high; however, recent international studies suggest the cost of “doing nothing” is itself significant. This study aimed to develop a preliminary estimate of the economic cost of health inequities between Māori (indigenous) and non-Māori children in New Zealand. Methods Standard quantitative epidemiological methods and “cost of illness” methodology were employed, within a Kaupapa Māori theoretical framework. Data were obtained from national data collections held by the New Zealand Health Information Service and other health sector agencies. Results Preliminary estimates suggest child health inequities between Māori and non-Māori in New Zealand are cost-saving to the health sector. However the societal costs are significant. A conservative “base case” scenario estimate is over $NZ62 million per year, while alternative costing methods yield larger costs of nearly $NZ200 million per annum. The total cost estimate is highly sensitive to the costing method used and Value of Statistical Life applied, as the cost of potentially avoidable deaths of Māori children is the major contributor to this estimate. Conclusions This preliminary study suggests that health sector spending is skewed towards non-Māori children despite evidence of greater Māori need. Persistent child health inequities result in significant societal economic costs. Eliminating child health inequities, particularly in primary care access, could result in significant economic benefits for New Zealand. However, there are conceptual, ethical and methodological challenges in estimating the economic cost of child health inequities. Re-thinking of traditional economic frameworks and development of more appropriate methodologies is required. PMID:22640030
Piram, Maryam; Frenkel, Joost; Gattorno, Marco; Ozen, Seza; Lachmann, Helen J; Goldbach-Mansky, Raphaela; Hentgen, Véronique; Neven, Bénédicte; Stankovic Stojanovic, Katia; Simon, Anna; Kuemmerle-Deschner, Jasmin; Hoffman, Hal; Stojanov, Silvia; Duquesne, Agnès; Pillet, Pascal; Martini, Alberto; Pouchot, Jacques; Koné-Paut, Isabelle
2012-01-01
Background The systemic autoinflammatory disorders (SAID) share many clinical manifestations, albeit with variable patterns, intensity and frequency. A common definition of disease activity would be rational and useful in the management of these lifelong diseases. Moreover, standardised disease activity scores are required for the assessment of new therapies in constant development. The aim of this study was to develop preliminary activity scores for familial Mediterranean fever, mevalonate kinase deficiency, tumour necrosis factor receptor-1-associated periodic syndrome and cryopyrin-associated periodic syndromes (CAPS). Methods The study was conducted using two well-recognised consensus formation methods: the Delphi technique and the nominal group technique. The results from a two-step survey and data from parent/patient interviews were used as preliminary data to develop the agenda for a consensus conference to build a provisional scoring system. Results 24 of 65 experts in SAID from 20 countries answered the web questionnaire and 16 attended the consensus conference. There was consensus agreement to develop separate activity scores for each disease but with a common format based on patient diaries. Fever and disease-specific clinical variables were scored according to their severity. A final score was generated by summing the score of all the variables divided by the number of days over which the diary was completed. Scores varied from 0 to 16 (0–13 in CAPS). These scores were developed for the purpose of clinical studies but could be used in clinical practice. Conclusion Using widely recognised consensus formation techniques, preliminary scores were obtained to measure disease activity in four main SAID. Further prospective validation study of this instrument will follow. PMID:21081528
The cost of child health inequalities in Aotearoa New Zealand: a preliminary scoping study.
Mills, Clair; Reid, Papaarangi; Vaithianathan, Rhema
2012-05-28
Health inequalities have been extensively documented, internationally and in New Zealand. The cost of reducing health inequities is often perceived as high; however, recent international studies suggest the cost of "doing nothing" is itself significant. This study aimed to develop a preliminary estimate of the economic cost of health inequities between Māori (indigenous) and non-Māori children in New Zealand. Standard quantitative epidemiological methods and "cost of illness" methodology were employed, within a Kaupapa Māori theoretical framework. Data were obtained from national data collections held by the New Zealand Health Information Service and other health sector agencies. Preliminary estimates suggest child health inequities between Māori and non-Māori in New Zealand are cost-saving to the health sector. However the societal costs are significant. A conservative "base case" scenario estimate is over $NZ62 million per year, while alternative costing methods yield larger costs of nearly $NZ200 million per annum. The total cost estimate is highly sensitive to the costing method used and Value of Statistical Life applied, as the cost of potentially avoidable deaths of Māori children is the major contributor to this estimate. This preliminary study suggests that health sector spending is skewed towards non-Māori children despite evidence of greater Māori need. Persistent child health inequities result in significant societal economic costs. Eliminating child health inequities, particularly in primary care access, could result in significant economic benefits for New Zealand. However, there are conceptual, ethical and methodological challenges in estimating the economic cost of child health inequities. Re-thinking of traditional economic frameworks and development of more appropriate methodologies is required.
Catunda, I S; Vasconcelos, B C do E; Andrade, E S de S; Costa, D F N
2016-08-01
The aim of the present preliminary study was to investigate the effectiveness of an avocado-soybean unsaponifiable extract (ASU) in patients with arthralgia and osteoarthritis of the temporomandibular joint (TMJ). A randomized, double-blind, placebo-controlled trial was carried out. Fourteen women diagnosed with arthralgia and osteoarthritis of the TMJ using the Research Diagnostic Criteria for Temporomandibular Disorders were included in the statistical analysis. The women were allocated randomly to two groups: ASU group and placebo group. Pain was measured using a visual analogue scale and pressure algometer. Mandibular function was evaluated through measurement of mandibular movements. Quality of life was measured using the Oral Health Impact Profile (OHIP-14). The medication (ASU capsules or placebo capsules) was used for 4 months and the total follow-up was 6 months. Those taking the ASU extract had a decrease in pain symptoms and an improvement in quality of life. Moreover, a significant reduction in the use of rescue medication was found in the ASU group compared to the placebo group. This preliminary study provides strong evidence of the effectiveness of an avocado-soybean unsaponifiable extract in patients with degenerative joint diseases and arthralgia in the TMJ. Further studies with larger samples should be performed. Copyright © 2016 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
Ying, Liying; Wu, Lai Har; Wu, Xiangli; Shu, Jing; Loke, Alice Yuen
2018-04-01
Infertility affects both women and men in the physical, emotional, existential, and interpersonal realms. When couples seek in vitro fertilisation (IVF) treatment, they further suffer from the difficulties of the treatment and the uncertainty of its outcome. The aim of this study was to develop a preliminary conceptual framework for couples undergoing IVF treatment to give health professionals a better understanding of the experiences of such couples, and to guide the development of an intervention. The process of identifying frameworks adopted in intervention studies confirmed that there is no established framework for infertile couples undergoing IVF treatment. A skeletal framework identified from previous studies provides an internal structure for the proposed framework for couples undergoing IVF treatment, filled out with concepts drawn from a concept analysis and a qualitative study, knitting the structure together. This preliminary framework is the Endurance with Partnership Conceptual Framework (P-EPCF). It consists of four domains: the impacts of infertility and stressors, dyadic mediators, dyadic moderators and dyadic outcomes. According to the P-EPCF, the impacts of infertility and IVF treatment can be mediated by the couples' partnership and dyadic coping. Improvements in the psychological well-being and marital functioning of IVF couples can then be expected. The P-EPCF would be potentially valuable in guiding the development of a complex, couple-based intervention, which could focus on enhancing the partnership of couples and their coping strategies.
Rapid Dispersion of Polymicrobial Wound Biofilms with Depolymerase Enzymes
2012-11-01
reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing this collection of...second annual report for DM102823. The first annual report covered the following aims: Aim 1. Task 1. IACUC review Aim 1. Task 2. Bioinformatic...mannosidase from New England Biolabs and evaluated its anti -biofilm properties. Preliminary data (figure, next page) suggests that this enzyme cleaves
ERIC Educational Resources Information Center
Hostyn, Ine; Petry, Katja; Lambrechts, Greet; Maes, Bea
2011-01-01
Background: Affective and reciprocal interactions with others are essential for persons with profound intellectual and multiple disabilities (PIMD), but it is a challenge to assess their quality. This study aimed to investigate the usefulness of instruments from parent-infant research to evaluate these interactions. Method: Eighteen videotaped…
ERIC Educational Resources Information Center
St John, Jacqueline D.; Keller, Jane
Based on a preliminary version of this study, project aims were to learn what college freshmen knew about presidents in office from the late 19th century to the present and to determine the students' writing levels. During the first class of each of five semesters, students enrolled in an American History Since 1985 course were asked to write one…
ERIC Educational Resources Information Center
Wilson, Kenesha; Copeland-Solas, Eddia; Guthrie-Dixon, Natalie
2016-01-01
Mind mapping was introduced as a culturally relevant pedagogy aimed at enhancing the teaching and learning experience in a general education, Environmental Science class for mostly Emirati English Language Learners (ELL). Anecdotal evidence suggests that the students are very artistic and visual and enjoy group-based activities. It was decided to…
Social networking sites use and the morphology of a social-semantic brain network.
Turel, Ofir; He, Qinghua; Brevers, Damien; Bechara, Antoine
2017-09-30
Social lives have shifted, at least in part, for large portions of the population to social networking sites. How such lifestyle changes may be associated with brain structures is still largely unknown. In this manuscript, we describe two preliminary studies aimed at exploring this issue. The first study (n = 276) showed that Facebook users reported on increased social-semantic and mentalizing demands, and that such increases were positively associated with people's level of Facebook use. The second study (n = 33) theorized on and examined likely anatomical correlates of such changes in demands on the brain. Findings indicated that the grey matter volumes of the posterior parts of the bilateral middle and superior temporal, and left fusiform gyri were positively associated with the level of Facebook use. These results provided preliminary evidence that grey matter volumes of brain structures involved in social-semantic and mentalizing tasks may be linked to the extent of social networking sites use.
Urban simulation and gaming: Preliminary experience and perspectives, appendix F
NASA Technical Reports Server (NTRS)
Shostak, A. B.
1973-01-01
A three-month summer study of gaming, as applied to urban problems, was conducted. The results of the study are presented along with a series of recommendations aimed at guiding the warranted efforts of others to further explore the application of scientific gaming to the solution of some of America's urban problems. Three main topics are considered and are discussed in depth. These include: (1) gaming and urbanology, (2) methodology and lessons, and (3) reforms in the Cities Game.
Sunaguchi, Naoki; Yuasa, Tetsuya; Hyodo, Kazuyuki; Zeniya, Tsutomu
2013-01-01
We propose a 3-dimensional fluorescent x-ray computed tomography (CT) pinhole collimator, aimed at providing molecular imaging with quantifiable measures and sub-millimeter spatial resolution. In this study, we demonstrate the feasibility of this concept and investigate imaging properties such as spatial resolution, contrast resolution and quantifiable measures, by imaging physical phantoms using a preliminary imaging system developed with monochromatic synchrotron x rays constructed at the BLNE-7A experimental line at KEK, Japan.
PLCO Ovarian Phase III Validation Study — EDRN Public Portal
Our preliminary data indicate that the performance of CA 125 as a screening test for ovarian cancer can be improved upon by additional biomarkers. With completion of one additional validation step, we will be ready to test the performance of a consensus marker panel in a phase III validation study. Given the original aims of the PLCO trial, we believe that the PLCO represents an ideal longitudinal cohort offering specimens for phase III validation of ovarian cancer biomarkers.
The study on length and diameter ratio of nail as preliminary design for slope stabilization
NASA Astrophysics Data System (ADS)
Gunawan, Indra; Silmi Surjandari, Niken; Muslih Purwana, Yusep
2017-11-01
Soil nailing technology has been widely applied in practice for reinforced slope. The number of studies for the effective design of nail-reinforced slopes has also increased. However, most of the previous study was focused on a safety factor of the slope; the ratio of length and diameter itself has likely never been studied before. The aim of this study is to relate the length and diameter ratio of the nail with the safety factor of the 20 m height of sand slope in the various angle of friction and steepness of the slope. Simplified Bishop method was utilized to analyze the safety factor of the slope. This study is using data simulation to calculate the safety factor of the slope with soil nailing reinforcement. The results indicate that safety factor of slope stability increases with the increase of length and diameter ratio of the nail. At any angle of friction and steepness of the slope, certain effective length and diameter ratio was obtain. These results may be considered as a preliminary design for slope stabilization.
NASA Astrophysics Data System (ADS)
Beer, Franziska; Passow, Harald
2008-02-01
The aim of the study is the construction of a test assembly, which facilitates objective, comparative studies on the cutting performance of lasers in hard tissue. To ensure the applicability of our own construction for the reproducible performance of laser incisions in hard tissue, eleven freshly extracted blocks (2×1.5cm2) of human bone were prepared with a Er,Cr:YSGG laser by using a handheld handpiece, respectively, using the constructed device for a standardized cutting. A total of 44 cuts were executed. The specimen were then histologically evaluated. The standard test assembly met the requirements concerning the provision of objective results. The findings of the histological evaluation prove the reproducibility of the results. The standard test assembly presented in this paper facilitates comparative studies of different laser systems by reducing subjective influence on the preparation to a minimum. The results of this preliminary study show that the precision of the guiding instrument for laser cutting reduces the error of cut width by 50-fold, from 50to1μm.
Crenshaw, Tanya L.; Chambers, Erin W.; Heeren, Cinda; Metcalf, Heather E.
2017-01-01
Just over 10 years ago, we conducted a culture study of the Computer Science Department at the flagship University of Illinois at Urbana-Champaign, one of the top five computing departments in the country. The study found that while the department placed an emphasis on research, it did so in a way that, in conjunction with a lack of communication and transparency, devalued teaching and mentoring, and negatively impacted the professional development, education, and sense of belonging of the students. As one part of a multi-phase case study spanning over a decade, this manuscript presents preliminary findings from our latest work at the university. We detail early comparisons between data gathered at the Department of Computer Science at the University of Illinois at Urbana-Champaign in 2005 and our most recent pilot case study, a follow-up research project completed in 2016. Though we have not yet completed the full data collection, we find it worthwhile to reflect on the pilot case study data we have collected thus far. Our data reveals improvements in the perceptions of undergraduate teaching quality and undergraduate peer mentoring networks. However, we also found evidence of continuing feelings of isolation, incidents of bias, policy opacity, and uneven policy implementation that are areas of concern, particularly with respect to historically underrepresented groups. We discuss these preliminary follow-up findings, offer research and methodological reflections, and share next steps for applied research that aims to create positive cultural change in computing. PMID:28579969
Dating ancient mosaic glasses by luminescence: The case study of San Pietro in Vaticano
NASA Astrophysics Data System (ADS)
Galli, A.; Martini, M.; Sibilia, E.; Vandini, M.; Villa, I.
2011-12-01
The preliminary results of a study on the dosimetric properties of a set of glass tesserae from the mosaics of the vaults of St. Peter's Basilica in Rome (late XVI century) are reported. The main goal of the research was to assess the possibility of dating them by means of luminescence techniques. The samples had already been extensively studied and investigated from a historical, artistic and compositional point of view. The period of the making of the mosaic was rather well known, and could be the basis to test the experimental procedures we used for dosimetry. The experiments also aimed at demonstrating the validity of the hypothesis we put forward, i.e. the positive link between the presence of micro-crystals and the luminescence sensitivity in mosaic glass: to this aim, the samples richer in crystalline inclusions were selected. The role of calcium antimonate and cassiterite was definitely demonstrated. For what concerns their thermoluminescence (TL) characteristics, a preliminary investigation suggested that the available configuration of the detection systems did not properly fit the wavelength of the emitted TL. Much more promising results have been achieved by the use of Optically Stimulated Luminescence (OSL), even if the measured absorbed doses were rather scattered. For one sample with high OSL sensitivity, it was possible to establish its recent age, relative to one of the documented restorations that took place during the last century.
A pilot study to evaluate the effects of floatation spa treatment on patients with osteoarthritis.
Hill, S; Eckett, M J; Paterson, C; Harkness, E F
1999-12-01
To conduct a preliminary investigation of the effects on floatation spa therapy on quality of life in patients with osteoarthritis to see if controlled trials are warranted. Uncontrolled clinical trial. Private floatation spa therapy centre. Fourteen patients with chronic osteoarthritis of the weight-bearing joints, of whom four dropped out. Six weekly sessions of floatation spa therapy. SF36, AIMS2 and MYMOP quality-of-life questionnaires. All patients improved. Differences between baseline and discharge scores showed statistically significant improvement for MYMOP, but not AIMS2 or SF-36. Controlled trials of floatation spa therapy for patients with osteoarthritis are warranted.
ERIC Educational Resources Information Center
Ronen, Tammie; Rosenbaum, Michael
2010-01-01
This article describes a school-based aggression reduction intervention program aiming to impart highly aggressive adolescents with a learned resourcefulness repertoire, using Ronen and Rosenbaum's four-module self-control model. Intervention aimed to teach adolescents that aggression is changeable behavior resulting from how they think and feel,…
NASA Technical Reports Server (NTRS)
Michal, Todd R.
1998-01-01
This study supports the NASA Langley sponsored project aimed at determining the viability of using Euler technology for preliminary design use. The primary objective of this study was to assess the accuracy and efficiency of the Boeing, St. Louis unstructured grid flow field analysis system, consisting of the MACGS grid generation and NASTD flow solver codes. Euler solutions about the Aero Configuration/Weapons Fighter Technology (ACWFT) 1204 aircraft configuration were generated. Several variations of the geometry were investigated including a standard wing, cambered wing, deflected elevon, and deflected body flap. A wide range of flow conditions, most of which were in the non-linear regimes of the flight envelope, including variations in speed (subsonic, transonic, supersonic), angles of attack, and sideslip were investigated. Several flowfield non-linearities were present in these solutions including shock waves, vortical flows and the resulting interactions. The accuracy of this method was evaluated by comparing solutions with test data and Navier-Stokes solutions. The ability to accurately predict lateral-directional characteristics and control effectiveness was investigated by computing solutions with sideslip, and with deflected control surfaces. Problem set up times and computational resource requirements were documented and used to evaluate the efficiency of this approach for use in the fast paced preliminary design environment.
Preliminary study of the pilot's workload during emergency procedures in helicopters air operations.
Bezerra, Flávio G V; Ribeiro, Selma L O
2012-01-01
Military air operations and law enforcement operations in helicopters are examples of activities that require high performance of the operator. This article aimed at presenting a preliminary analysis of data obtained in the initial study in order to validate the instruments and the research protocol that focuses on the analysis of the workload imposed on helicopter pilots in emergency situations. The research was conducted in an environment of real flight training and used the NASA-TLX Scale to assess the workload and an interview guide to obtain reports on the main tasks performed. Preliminary data obtained is related to the participation of 10 (ten) volunteer pilots with experience in different types of helicopters. Four scenarios involving helicopter emergency procedures of HB-350 "Squirrel" were outlined. For this article, the analysis used only the data regarding the Physical and Mental Demands of the NASA-TLX Scale. Preliminarily, the results indicate that the "time pressure" as a factor contributing to increase mental requirement in emergency situations in flight, and that this increase was reflected in the request of mental processes such as: identification of the breakdown, attention and monitoring parameters. Future steps include extending the sample and adding physiological tools to better understand the effects of these types of emergencies on pilot performance and flight safety.
Oberman, Lindsay M
2012-12-01
The CDC currently estimates the prevalence of autism spectrum disorders (ASD) at 1 in 88 children. Though the exact etiology of ASD is unknown, recent studies implicate synaptic maturation and plasticity in the pathogenesis of ASD leading to an imbalance of excitation and inhibition, and specifically a disproportionately high level of excitation. Pharmacological agents that modulate excitation and inhibition are currently in clinical trials for treatment of ASD and show promising preliminary results. This paper reviews the literature implicating the role of glutamate and GABA pathways in the pathophysiology of ASD. It also provides a review of the current results from both animal models and human clinical trials of drugs aimed at normalizing the imbalance of excitation and inhibition through the use of metabotropic glutamate receptor (mGluR) antagonists and GABA agonists. Both mGluR antagonists and GABA agonists have promising preliminary data from animal model and small-scale Phase II human trials. They show significant efficacy in subpopulations and appear to have favorable side-effect profiles. Though preliminary data are extremely promising, results from ongoing larger, double-blind, placebo-controlled studies will give a more complete understanding of the efficacy and side-effect profile related to these drugs.
A preliminary conceptual framework for cancer couple dyads: live with love.
Li, Qiuping; Loke, Alice Y
2015-01-01
With the research focus on family caregiving shifting from the individual to the dyadic level, there is a need to develop a conceptual framework that focused on caregiver-patient dyads. The aim of this study was to develop a preliminary conceptual framework for cancer couple dyads, to "Live With Love." A literature search was conducted among 4 electronic databases to identify couple-based intervention studies related to couples coping with cancer. This report differs from a traditional literature review in that we synthesized the models or frameworks used in these studies rather than the outcomes of the studies. A preliminary Live With Love Conceptual Framework (P-LLCF) for cancer couple dyads was developed based on the conceptual frameworks adopted in related literature on spousal caregiving for patients with cancer. This P-LLCF contains 3 domains: event situation, dyadic mediators, and caregiver-patient dyads (appraisal, coping, and adjustment/outcomes). The various components in this P-LLCF will work together to benefit the positive dyadic adjustment/outcomes of the spousal caregiver-patient dyads in the cancer dyads' journey of coping with cancer. This P-LLCF sheds new light on the study of cancer couple dyads. It will be potentially valuable for guiding the related research and development of interventions on cancer couple dyads. Future research is needed to assess the outcome of interventions that focus on different components. It is also needed to develop measurements to assess dyadic adjustment/outcomes in nursing practice.
Harder, Sönke; Wolfart, Stefan; Egert, Christopher; Kern, Matthias
2011-10-01
The aim of this preliminary prospective study was to evaluate the clinical outcome, the oral health-related quality of life (OHRQoL), and the subjective chewing ability of patients with mandibular complete dentures retained by a single implant placed in the mandible midline. Patients wearing complete dentures were treated with a single implant in the mandible, followed by relining of the dentures and incorporation of ball attachments for implant retention. Implant outcome, prosthodontic maintenance, subjective chewing ability, and the oral health impact profile of the patients were assessed at baseline and at four weeks after connecting the denture and implant. Eleven patients were enrolled in this investigation, and the mean observation period was 43.4 months (minimum period: 35, maximum period: 52 months). No implants were lost during observation period, but four dentures needed repair because of the fracture of the denture base in the midline area. A significant improvement was observed in the OHRQoL of the patients after the attachment of the mandibular dentures with a single midline implant. Furthermore, the subjective chewing ability of the patients was significantly improved after implant connection. Within the limitations of this preliminary prospective clinical study, single implant-supported mandibular overdentures were a successful treatment option for older edentulous patients who showed improvements in their OHRQoL and chewing ability. Copyright © 2011 Elsevier Ltd. All rights reserved.
Zieliński, Rafał; Kobos, Jozef; Zakrzewska, Anna
While Ki-67 expression is frequently used as an indicator of tumor cell proliferation, alternative markers have also been proposed. Possible alternative indicators of proliferation are the minichromosome maintenance (MCM) proteins, whose levels are inversely associated with tumor cell differentiation. The aim of this preliminary study was to compare the levels of Ki-67 and MCM-3 expression in major salivary gland epithelial tumors in all children and adolescents who underwent surgery in our department in the years 2009-2014. The histopathological diagnosis of the subjects was reviewed, as well as the expression of Ki-67 and MCM-3 in post-op specimens of the tumors. The normality of data was checked with the Shapiro-Wilk test. The t test for independent variables or the U test was used as appropriate to determine statistically significant differences in the expression of Ki-67 and MCM-3. Five cases of pleomorphic adenoma, one of myoepithelioma, one of basal cell adenoma and one of mucoepidermoid carcinoma were identified. Significantly greater MCM-3 than Ki-67 expression was observed in every case. The results of our preliminary study emphasize the need for future research on MCM-3 as a sensitive proliferation marker, providing an alternative to Ki-67, in cases of various major salivary gland epithelial tumors in children and adolescents.
Bidari, Ali; Hassanzadeh, Morteza; Ghavidel Parsa, Banafsheh; Kianmehr, Nahid; Kabir, Ali; Pirhadi, Sara; Sayfi, Mohammad; Toutounchi, Mehrangiz; Fattahi, Fariba; Zandi Karimi, Fereidoon
2013-12-01
The aim of this study was to validate the 2010 American College of Rheumatology (ACR) preliminary criteria for fibromyalgia (FM) in an Iranian population. In this multicenter prospective study, we enrolled 168 FM patients and 110 controls. All participants underwent dolorimetry examination by study assessors and completed a questionnaire containing variables of both the ACR 2010 preliminary and ACR 1990 criteria. We compared the performance of the ACR 2010 criteria with the expert diagnosis as well as the ACR 1990 criteria. Receiver operator characteristic analyses and Youden index were used to evaluate the test characteristics of a set of different cutoff points for two subcomponents of ACR 2010 criteria including widespread pain index (WPI) and symptom severity (SS) scale. Considering expert diagnosis as the gold standard, the ACR 2010 criteria showed comparable specificity with ACR 1990 (92.8 vs. 88.3 %, P = 0.073), but lower sensitivity (58.9 vs. 71.4 %, P = 0.003) and a tendency for lower accuracy (72.4 vs. 78.4 %, P = 0.105). Applying the ACR 1990 criteria as the gold standard, we observed a trend toward an increase in overall accuracy (72.4 vs. 79.1 %, P = 0.064). Optimal test characteristics were achieved for WPI ≥6 and SS scale score ≥4 and improved sensitivity and accuracy of ACR 2010 criteria when compared to expert, 76.1 and 81.7, respectively. The preliminary ACR 2010 criteria performed less desirably in terms of sensitivity in our set of Iranian patients. Selecting lower cutoff points as WPI ≥6 and SS scale score ≥4 improved the diagnostic values of the criteria.
Programmable multi-zone furnace for microgravity research
NASA Technical Reports Server (NTRS)
Rosenthal, Bruce N.; Krolikowski, Cathryn R.
1991-01-01
In order to provide new furnace technology to accommodate microgravity research studies and commercial applications in material processes, research has been initiated on the development of the Programmable-Multi-zone Furnace (PMZF). The PMZF is described as a multi-user materials processing furnace facility that is composed of thirty or more heater elements in series on a muffle tube or in a stacked ring-type configuration and independently controlled by a computer. One of the aims of the PMZF project is to allow furnace thermal gradient profiles to be reconfigured without physical modification of the hardware by creating the capability of reconfiguring thermal profiles in response to investigators' requests. The future location of the PMZF facility is discussed; the preliminary science survey results and preliminary conceptual designs for the PMZF are presented; and a review of multi-zone furnace technology is given.
Site Studies for the SuperB Collider and Synchrotron Radiation Facility Project
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tomassini, S.; Biagini, M.E.; Raimondi, P.
2012-04-26
The SuperB complex project aims at the construction of a very high luminosity (10{sup 36} cm{sup -2}s{sup -1}) asymmetric e{sup +}e{sup -} B-factory and a few X-ray synchrotron beam lines (SR). The project has been recently approved by the Italian Government as part of the National Research Plan. The Tor Vergata University location has been chosen and a Consortium among INFN, University of Rome II Tor Vergata and the Research Ministry is being signed, allowing for the constitution of the 'Cabibbo Laboratory', where the SuperB project will be hosted. This paper presents and describes the status of the preliminary designmore » of the site layout, related issues for the chosen site and the preliminary ground motion (GM) measurement results.« less
NASA Technical Reports Server (NTRS)
Hoadley, A. W.; Porter, A. J.
1990-01-01
This paper presents data on a preliminary analysis of the thermal dynamic characteristics of the Airborne Information Management System (AIMS), which is a continuing design project at NASA Dryden. The analysis established the methods which will be applied to the actual AIMS boards as they become available. The paper also describes the AIMS liquid cooling system design and presents a thermodynamic computer model of the AIMS cooling system, together with an experimental validation of this model.
The Diffusion of mHealth Applications.
Gallos, Parisis; Mantas, John
2017-01-01
The aim of this preliminary study is to present the usage behaviour of mHealth applications. A survey was conducted among 352 Smartphone users; 109 of them had used mHealth applications as well. The usage of these applications seemed to be quite low. Young people had used mHealth applications more than the elders. Also, there was not found a statistically significant relationship between the gender and the usage of mHealth applications.
Ondrejka, R; Durove, A; Svrcek, S; Benísek, Z; Süliová, J
1997-02-01
The study was aimed at isolation and subsequent identification of strains of rabies virus by means of monoclonal antibodies from foxes killed in the vaccination zone within the complex preliminary monitoring of oral antirabies vaccination. The results obtained indicate that the vaccines for oral antirabies vaccination used in Slovakia did not contain any vaccination strain pathogenic to the extremely sensitive target species-the fox (Vulpes vulpes).
Neutron capture measurement on {sup 173}Lu at LANSCE with DANCE detector
DOE Office of Scientific and Technical Information (OSTI.GOV)
Theroine, C.; Ebran, A.; Meot, V.
2013-06-10
The (n,{gamma}) cross section on the unstable {sup 173}Lu(t{sub 1/2} = 1.37y) has been measured from thermal energy up to 200 eV at Los Alamos Neutron Science Center (LANSCE) with The Detector for Advanced Neutron Capture Experiements (DANCE). The main aim of this study is to validate and optimize reaction models for unstable nucleus. A preliminary capture yield will be presented in this paper.
In Search of Cosmic Rays: A Student Physics Project Aimed at Finding the Origin of Cosmic Rays.
ERIC Educational Resources Information Center
Antonelli, Jamie; Mahoney, Sean; Streich, Derek; Liebl, Michael
2001-01-01
Describes an ongoing project, the Cosmic Ray Observatory Project (CROP), being conducted by the University of Nebraska in partnership with several high schools. Each school group has installed cosmic ray detectors, and initial activities have included calibrating equipment, gathering preliminary data, and learning about cosmic ray showers. Aims to…
Canullo, Luigi; Dellavia, Claudia
2009-10-01
The aim of this preliminary study was to evaluate histologically a nanocrystalline hydroxyapatite silica gel in maxillary sinus floor grafting in severely resorbed maxillae. A total of 16 consecutive patients scheduled for sinus lift were recruited during this study. Patients were randomly divided in two groups, eight patients each. In both groups, preoperative residual bone level ranged between 1 and 3 mm (mean value of 2.03 mm). No membrane was used to occlude the buccal window. Second surgery was carried out after a healing period of 3 months in Group 1 and 6 months in Group 2. Using a trephine bur, one bone specimen was harvested from each augmented sinus and underwent histological and histomorphometric analysis. Histological analysis showed significant new bone formation and remodeling of the grafted material. In the cores obtained at 6 months, regenerated bone, residual NanoBone, and bone marrow occupied respectively 48 +/- 4.63%, 28 +/- 5.33%, and 24 +/- 7.23% of the grafted volume. In the specimens taken 3 months after grafting, mean new bone was 8 +/- 3.34%, mean NanoBone was 45 +/- 5.10%, and mean bone marrow was 47 +/- 6.81% of the bioptical volume. Within the limits of this preliminary prospective study, it was concluded that grafting of maxillary sinus using nanostructured hydroxyapatite silica gel as only bone filler is a reliable procedure also in critical anatomic conditions and after early healing period.
Hypoallergenic properties of donkey's milk: a preliminary study.
Vincenzetti, Silvia; Foghini, Laura; Pucciarelli, Stefania; Polzonetti, Valeria; Cammertoni, Natalina; Beghelli, Daniela; Polidori, Paolo
2014-01-01
Cow's milk protein allergy (CMPA) is an abnormal immunological response to cow milk proteins, which results in IgE-mediated reactions. The therapeutic strategy to respond to CMPA envisages the total elimination of milk or the administration of cow's milk substitutes. For this reason the use of milk from other mammalian species was tested. Among them, donkey's milk proved to be the best alternative in feeding infants affected by CMPA, since its chemical composition is comparable to human milk. In this work an in vitrostudy was performed in order to analyze the IgE reactivity to milk protein allergens from cow, donkey and goat. In particular, immunoblotting experiments using sera from milk-allergic and non-allergic adult volunteers were conducted with the aim of verifying the hypoallergenic property of donkey's milk. This study provided a preliminary evidence of the hypoallergenicity of donkey's milk when compared to bovine and goat milk. Considering the obtained results, it would be possible to develop a sensitive diagnostic method for CMPA detection, based on chromatographic and immunoblotting analysis.
Mitchell, John T; McIntyre, Elizabeth M; English, Joseph S; Dennis, Michelle F; Beckham, Jean C; Kollins, Scott H
2017-11-01
Mindfulness meditation training is garnering increasing empirical interest as an intervention for ADHD in adulthood, although no studies of mindfulness as a standalone treatment have included a sample composed entirely of adults with ADHD or a comparison group. The aim of this study was to assess the feasibility, acceptability, and preliminary efficacy of mindfulness meditation for ADHD, executive functioning (EF), and emotion dysregulation symptoms in an adult ADHD sample. Adults with ADHD were stratified by ADHD medication status and otherwise randomized into an 8-week group-based mindfulness treatment ( n = 11) or waitlist group ( n = 9). Treatment feasibility and acceptability were positive. In addition, self-reported ADHD and EF symptoms (assessed in the laboratory and ecological momentary assessment), clinician ratings of ADHD and EF symptoms, and self-reported emotion dysregulation improved for the treatment group relative to the waitlist group over time with large effect sizes. Improvement was not observed for EF tasks. Findings support preliminary treatment efficacy, though require larger trials.
Preliminary Analysis of High-Flux RSG-GAS to Transmute Am-241 of PWR’s Spent Fuel in Asian Region
NASA Astrophysics Data System (ADS)
Budi Setiawan, M.; Kuntjoro, S.
2018-02-01
A preliminary study of minor actinides (MA) transmutation in the high flux profile RSG-GAS research reactor was performed, aiming at an optimal transmutation loading for present nuclear energy development. The MA selected in the analysis includes Am-241 discharged from pressurized water reactors (PWRs) in Asian region. Until recently, studies have been undertaken in various methods to reduce radiotoxicity from actinides in high-level waste. From the cell calculation using computer code SRAC2006, it is obtained that the target Am-241 which has a cross section of the thermal energy absorption in the region (group 8) is relatively large; it will be easily burned in the RSG-GAS reactor. Minor actinides of Am-241 which can be inserted in the fuel (B/T fuel) is 2.5 kg which is equivalent to Am-241 resulted from the partition of spent fuel from 2 units power reactors PWR with power 1000MW(th) operated for one year.
Samsel, R; Chmura, A; Włodarczyk, Z; Wyzgał, J; Cieciura, T; Lagiewska, B; Pliszczyński, J; Korczak, G; Lazowski, T; Paczek, L; Wałaszewski, J; Lao, M; Rowiński, W
1999-01-01
Monoclonal and polyclonal antilymphocyte antibodies have been used successfully in organ transplantation as induction therapy and in the treatment of acute graft rejection. Used for induction the medication is generally given for the first 7-10 days. The aim of this study was to assess the safety and efficacy of single high dose (9 mg/kg) ATG Fresenius S given perioperatively, before revascularization, to kidney allograft recipients. During last twelve months seventy six, first cadaveric kidney adult recipients were included into the study in two centers (center A-64, center B-12). All patients received triple drug immunosuppression (Neoral, steroids and Cellcept which was replaced by azathioprine after 4 months), and were randomized to receive ATG or not. The follow-up period ranged from 1 month up to 1 year. The preliminary results are very promising, the rejection rate in bolus group was significantly lower than in control. No significant side effects or serious adverse events in both groups were observed.
Analysis of weight changes after left gastric artery embolization in a cancer-naive population
Kim, David J.; Raman, Hari S.; Salter, Amber; Ramaswamy, Raja; Gunn, Andrew J.; Weiss, Clifford R.; Akinwande, Olaguoke
2018-01-01
PURPOSE We aimed to evaluate weight changes after left gastric artery (LGA) embolization in a retrospective cancer-naive cohort. METHODS A retrospective study was conducted to identify patients who underwent LGA embolization for gastrointestinal bleeding (GI). Patients with known cancer diagnoses at the time of LGA embolization were excluded. Pre- and postprocedure weights were assessed. Statistical analysis was performed using paired t-test and Wilcoxon signed-rank test. RESULTS A total of 39 patients were identified. In 21 patients who had documented pre- and postprocedural weights, a median of 16.3 kg weight loss (P = 0.045) was observed over a median time of 12 months (range, 2–72). In patients who had pre- and postprocedure endoscopies (n=6), 2 had worsening ulcers following LGA embolization and 4 had stable or no abnormal findings. CONCLUSION Our preliminary observation suggests that LGA embolization is well tolerated and results in unintended weight loss. Larger studies are needed to confirm these preliminary findings. PMID:29757147
Shepard, Michele; Brenner, Sara
2014-01-01
Background: Numerous studies are ongoing in the fields of nanotoxicology and exposure science; however, gaps remain in identifying and evaluating potential exposures from skin contact with engineered nanoparticles in occupational settings. Objectives: The aim of this study was to identify potential cutaneous exposure scenarios at a workplace using engineered nanoparticles (alumina, ceria, amorphous silica) and evaluate the presence of these materials on workplace surfaces. Methods: Process review, workplace observations, and preliminary surface sampling were conducted using microvacuum and wipe sample collection methods and transmission electron microscopy with elemental analysis. Results: Exposure scenarios were identified with potential for incidental contact. Nanoparticles of silica or silica and/or alumina agglomerates (or aggregates) were identified in surface samples from work areas where engineered nanoparticles were used or handled. Conclusions: Additional data are needed to evaluate occupational exposures from skin contact with engineered nanoparticles; precautionary measures should be used to minimize potential cutaneous exposures in the workplace. PMID:25000112
Bianchini, F; Di Vita, A; Palermo, L; Piccardi, L; Blundo, C; Guariglia, C
2014-12-01
The aim of this study was to determine whether an egocentric topographical working memory (WM) deficit is present in the early stages of Alzheimer's disease (AD) with respect to other forms of visuospatial WM. Further, we would investigate whether this deficit could be present in patients having AD without topographical disorientation (TD) signs in everyday life assessed through an informal interview to caregivers. Seven patients with AD and 20 healthy participants performed the Walking Corsi Test and the Corsi Block-Tapping Test. The former test requires memorizing a sequence of places by following a path and the latter is a well-known visuospatial memory task. Patients with AD also performed a verbal WM test to exclude the presence of general WM impairments. Preliminary results suggest that egocentric topographical WM is selectively impaired, with respect to visuospatial and verbal WM, even without TD suggesting an important role of this memory in the early stages of AD. © The Author(s) 2014.
Tanja, Tilles-Tirkkonen; Outi, Nuutinen; Sakari, Suominen; Jarmo, Liukkonen; Kaisa, Poutanen; Leila, Karhunen
2015-01-01
Eating competence is an attitudinal and behavioral concept, based on The Satter Eating Competence Model. In adults, it has been shown to be associated with a higher quality of diet. Eating competence or its association with the quality of diet has not been studied in adolescents. The aim of the current study was to explore the utility of using a preliminary Finnish translation of the ecSI 2.0 for evaluating presumed eating competence and its association with food selection, meal patterns and related psychobehavioral factors in 10–17 year old adolescents. Altogether 976 10–17 years old Finnish adolescents filled in the study questionnaire. When exploring the construct validity of ecSI 2.0, the confirmatory factor analysis (CFA) indicated acceptable model fit and all four components of the ecSI 2.0 (eating attitudes, food acceptance, internal regulation of food intake, management of eating context) correlated with each other and were internally consistent. Over half (58%) of the adolescents scored 32 or higher and were thus classified as presumably eating competent (pEC). Eating competence was associated with greater meal frequency, more frequent consumption of vegetables and fruits, and more health-promoting family eating patterns. In addition the pEC, adolescents more often perceived their body size as appropriate, had less often tried to lose weight and had a higher self-esteem and a stronger sense of coherence than the not pEC ones. Family eating patterns and self-esteem were the main underlying factors of eating competence. In conclusion, this preliminary study suggests eating competence could be a useful concept to characterize eating patterns and related behaviors and attitudes in adolescents. However, these preliminary findings need to be confirmed in further studies with an instrument fully validated for this age group. PMID:26007335
Tanja, Tilles-Tirkkonen; Outi, Nuutinen; Sakari, Suominen; Jarmo, Liukkonen; Kaisa, Poutanen; Leila, Karhunen
2015-05-21
Eating competence is an attitudinal and behavioral concept, based on The Satter Eating Competence Model. In adults, it has been shown to be associated with a higher quality of diet. Eating competence or its association with the quality of diet has not been studied in adolescents. The aim of the current study was to explore the utility of using a preliminary Finnish translation of the ecSI 2.0 for evaluating presumed eating competence and its association with food selection, meal patterns and related psychobehavioral factors in 10-17 year old adolescents. Altogether 976 10-17 years old Finnish adolescents filled in the study questionnaire. When exploring the construct validity of ecSI 2.0, the confirmatory factor analysis (CFA) indicated acceptable model fit and all four components of the ecSI 2.0 (eating attitudes, food acceptance, internal regulation of food intake, management of eating context) correlated with each other and were internally consistent. Over half (58%) of the adolescents scored 32 or higher and were thus classified as presumably eating competent (pEC). Eating competence was associated with greater meal frequency, more frequent consumption of vegetables and fruits, and more health-promoting family eating patterns. In addition the pEC, adolescents more often perceived their body size as appropriate, had less often tried to lose weight and had a higher self-esteem and a stronger sense of coherence than the not pEC ones. Family eating patterns and self-esteem were the main underlying factors of eating competence. In conclusion, this preliminary study suggests eating competence could be a useful concept to characterize eating patterns and related behaviors and attitudes in adolescents. However, these preliminary findings need to be confirmed in further studies with an instrument fully validated for this age group.
ERIC Educational Resources Information Center
Muñoz Marín, Jorge Hugo; González Moncada, Adriana
2010-01-01
Distance web-based learning is a popular strategy in ELT teaching in Colombia. Despite of the growth of experiences, there are very few studies regarding teachers' participation in these courses. This paper reports preliminary findings of an on-going study aiming at exploring the roles that a teach er plays in an EFL reading comprehension distance…
g-factor measurements of isomeric states in 174W
NASA Astrophysics Data System (ADS)
Rocchini, M.; Nannini, A.; Benzoni, G.; Melon, B.; John, P. R.; Ur, C. A.; Avigo, R.; Bazzacco, D.; Blasi, N.; Bocchi, G.; Bottoni, S.; Bracco, A.; Camera, F.; Ceruti, S.; Crespi, F. C. L.; Georgiev, G.; Giaz, A.; Gottardo, A.; Leoni, S.; Menegazzo, R.; Mengoni, D.; Michelagnoli, C.; Million, B.; Modamio, V.; Morales, A. I.; Napoli, D. R.; Ottanelli, M.; Pellegri, L.; Perego, A.; Valiente-Dobon, J. J.; Wieland, O.
2016-05-01
The experimental setup GAMIPE used for gyro magnetic factor measurements at Laboratori Nazionali di Legnaro and a recent experimental work regarding K-isomers in 174W are described. Aim of the experiment is to study the detailed structure of the isomeric states wave functions, by the measurement of the magnetic dipole moments. This piece of information can provide interesting hints for theoretical models. Preliminary results concerning the population of the isomers of interest and half-lives are presented.
NASA Astrophysics Data System (ADS)
Hamdi, Boualem; Hamdi, Safia
The chemical and physical properties of a Algerian diatomite were given before and after heat treatment and chemical with an aim of a use in the heat insulation of constructions. The preliminary results obtained showed that this material is extremely porous (porosity >70 %), characterized of a low density and a very low thermal conductivity. These promising properties support the use of this local material in the thermal insulation.
Liburdi, Katia; Emiliani Spinelli, Sara; Benucci, Ilaria; Lombardelli, Claudio; Esti, Marco
2018-01-15
The aim of this study was to develop a bioreactor design for continuous milk coagulation using a biocatalyst composed of immobilized animal and vegetable rennet on aminated magnetic particles, which has been proven to be an appropriate carrier for enzyme immobilization. Calf and vegetable (Cynara cardunculus) rennets were covalently immobilized on CLEA® magnetic supports and the immobilization procedure was optimized in batch mode, by evaluating protein loading, caseinolytic activity and the coagulation properties of skim milk powder and cow's milk. Subsequently the optimal temperature of immobilized coagulant was defined and a technically-friendly enzyme bioreactor was developed in order to carry out a continuous milk coagulation process with the aim of producing soft cheese. Copyright © 2017 Elsevier Ltd. All rights reserved.
Outcomes of an illness self-management group using wellness recovery action planning.
Starnino, Vincent R; Mariscal, Susana; Holter, Mark C; Davidson, Lori J; Cook, Karen S; Fukui, Sadaaki; Rapp, Charles A
2010-01-01
The aim of this preliminary study was to examine the impact of participation in an illness self-management recovery program (Wellness Recovery Action Planning-WRAP) on the ability of individuals with severe mental illnesses to achieve key recovery related outcomes. A total of 30 participants from three mental health centers were followed immediately before and after engaging in a 12-week WRAP program. Three paired sample t-tests were conducted to determine the effectiveness of WRAP on hope, recovery orientation, and level of symptoms. A significant positive time effect was found for hope and recovery orientation. Participants showed improvement in symptoms, but the change was slightly below statistical significance. These preliminary results offer promising evidence that the use of WRAP has a positive effect on self-reported hope and recovery-related attitudes, thereby providing an effective complement to current mental health treatment.
Baldini, M; Coni, E; Mantovani, A; Stacchini, A; Zanasi, F
1989-01-01
The aim of this study was the evaluation of the effect of dietary imbalances on absorption and distribution of lead in the female Sprague-Dawley rat. In this note preliminary results on the relationship between blood concentrations of lead and unbalanced diets are presented. Hyperproteic, hyperglycidic, hyperlipidic and balanced diets were prepared, and most of them included 15 mg/kg lead. Blood samples were collected at day 0, 21, 36, and 95 of the diets and analyzed by anodic stripping voltammetry (ASV). Lead uptake as a function of feed consumption was found to decrease in the order: balanced, hyperproteic and hyperglycidic, hyperlipidic diet. On the other hand lead blood levels were as follows (decreasing order): hyperlipidic, hyperproteic, hyperglycidic, balanced. Further research is being carried out on the influences of dietary imbalances on whole-body distribution of lead.
Plasma brake model for preliminary mission analysis
NASA Astrophysics Data System (ADS)
Orsini, Leonardo; Niccolai, Lorenzo; Mengali, Giovanni; Quarta, Alessandro A.
2018-03-01
Plasma brake is an innovative propellantless propulsion system concept that exploits the Coulomb collisions between a charged tether and the ions in the surrounding environment (typically, the ionosphere) to generate an electrostatic force orthogonal to the tether direction. Previous studies on the plasma brake effect have emphasized the existence of a number of different parameters necessary to obtain an accurate description of the propulsive acceleration from a physical viewpoint. The aim of this work is to discuss an analytical model capable of estimating, with the accuracy required by a preliminary mission analysis, the performance of a spacecraft equipped with a plasma brake in a (near-circular) low Earth orbit. The simplified mathematical model is first validated through numerical simulations, and is then used to evaluate the plasma brake performance in some typical mission scenarios, in order to quantify the influence of the system parameters on the mission performance index.
NASA Astrophysics Data System (ADS)
Umami, M. K.
2018-01-01
This study is a preliminary survey on thumb reach of Indonesian population when interacting with single-handed device. This study was aimed to know the thumb reach envelope on the screen of mobile phone. The correlation between the thumb reach vs. the hand length and thumb length was also identified. Thirty young adults participated in the study. All participants had normal body stature and were right-handed person. In the observational phase, the participant was asked to colour the canvas area on the screen of the mobile phone by using his/her thumb. The participant had to complete the task by applying the single hand interaction. The participant should grab the mobile phone as he/she use it normally in his/her daily activities. The thumb reach envelope of participants was identified from the coloured area of the canvas. The results of this study found that participants with a large hand length and thumb length tend to have a large thumb reach. The results of this study also show the thumb reach area of the participants is forming an elliptical shape that runs from the northeast to southwest on the device screen.
Study of the Application of Separation Control by Unsteady Excitation to Civil Transport Aircraft
NASA Technical Reports Server (NTRS)
McLean, J. D.; Crouch, J. D.; Stoner, R. C.; Sakurai, S.; Seidel, G. E.; Feifel, W. M.; Rush, H. M.
1999-01-01
This study provides a preliminary assessment of the potential benefits of applying unsteady separation control to transport aircraft. Estimates are given for some of the costs associated with a specific application to high-lift systems. High-leverage areas for future research were identified during the course of the study. The study was conducted in three phases. Phase 1 consisted of a coarse screening of potential applications within the aerodynamics discipline. Potential benefits were identified and in some cases quantified in a preliminary way. Phase 2 concentrated on the application to the wing high-lift system, deemed to have the greatest potential benefit for commercial transports. A team of experts, including other disciplines (i.e. hydraulic, mechanical, and electrical systems, structures, configurations, manufacturing, and finance), assessed the feasibility, benefits, and costs to arrive at estimates of net benefits. In both phases of the study, areas of concern and areas for future research were identified. In phase 3 of this study, the high-leverage areas for future research were prioritized as a guide for future efforts aimed at the application of active flow control to commercial transport aircraft.
Di Fiore, Paola; Bussone, Gennaro; Galli, Alberto; Didier, Henri; Peccarisi, Cesare; D'Amico, Domenico; Frediani, Fabio
2017-05-01
Since chronic migraine is difficult to treat and often associated with medication overuse, non-invasive neurostimulation approaches are worth investigating. Transcutaneous supraorbital neurostimulation using the Cefaly ® device is promising as a non-invasive preventive treatment for episodic migraine, but no data are available for chronic migraine. Our aim was to perform a preliminary evaluation of the efficacy of the Cefaly ® device for the prophylaxis of chronic migraine with or without medication overuse. Primary endpoints were 50% reduction in monthly migraine days and 50% reduction in monthly medication use over 4 months. In an open-label study, twenty-three consecutive headache center patients with chronic migraine, diagnosed according to International Headache Society criteria, were recruited prospectively. After informed consent, patients were trained to use Cefaly ® and instructed to use it for 20 min daily over 4 months. All patients received active neurostimulation. Thirty-five percent of the patients enrolled in the study achieved the study endpoints. Over half the patients had a greater than 50% reduction in acute medication consumption.
A preliminary study of mechanistic approach in pavement design to accommodate climate change effects
NASA Astrophysics Data System (ADS)
Harnaeni, S. R.; Pramesti, F. P.; Budiarto, A.; Setyawan, A.
2018-03-01
Road damage is caused by some factors, including climate changes, overload, and inappropriate procedure for material and development process. Meanwhile, climate change is a phenomenon which cannot be avoided. The effects observed include air temperature rise, sea level rise, rainfall changes, and the intensity of extreme weather phenomena. Previous studies had shown the impacts of climate changes on road damage. Therefore, several measures to anticipate the damage should be considered during the planning and construction in order to reduce the cost of road maintenance. There are three approaches generally applied in the design of flexible pavement thickness, namely mechanistic approach, mechanistic-empirical (ME) approach and empirical approach. The advantages of applying mechanistic approach or mechanistic-empirical (ME) approaches are its efficiency and reliability in the design of flexible pavement thickness as well as its capacity to accommodate climate changes in compared to empirical approach. However, generally, the design of flexible pavement thickness in Indonesia still applies empirical approach. This preliminary study aimed to emphasize the importance of the shifting towards a mechanistic approach in the design of flexible pavement thickness.
Di Pierro, Francesco; Di Pasquale, Daniele; Di Cicco, Maurizio
2015-01-01
Secretory otitis media (SOM) remains a common disease among children. Although its cause is not yet perfectly established, the pathology, often a sequel of acute otitis media (AOM), is mainly characterized by persistent fluid in the middle ear cavity. Twenty-two children with a diagnosis of SOM were treated daily for 90 days with an oral formulation containing the oral probiotic Streptococcus salivarius K12 (Bactoblis®). After treatment, the children were evaluated for AOM episodes and subjected to tone audiometry, tympanometry, endonasal endoscopy, otoscopy, and tonsillar examination. Subject compliance and probiotic tolerability and side effects have also been evaluated. Our results indicate a good safety profile, a substantial reduction of AOM episodes, and a positive outcome from the treatment for all of the clinical outcomes tested. We conclude that strain K12 may have a role in reducing the occurrence and/or severity of SOM in children. From our perspective, this study constitutes a starting point toward the organization of a more extensive placebo-controlled study aimed at critically appraising our preliminary observations. PMID:26396541
Seroprevalence of Leishmaniasis Among Dogs Living in a Municipal Dog and Cat Shelter in Edirne.
Düzbeyaz, Ayşe; Şakru, Nermin; Töz, Seray
2016-06-01
In this study, we aimed to investigate the seroprevalence of canine leishmaniosis among dogs that live in the town center due to a lack of data on the prevalence of canine leishmaniasis (CanL) in Edirne. In the present study, 37 dogs living in a municipal dog and cat shelter in Edirne were screened for leishmaniosis by the ındirect fluorescent antibody test. All samples were found to be seronegative. Our study is a preliminary study for Edirne. We wish to perform a large-scale seroepidemiological study with a larger number of dogs from different regions and identify Phlebotomus species.
Rees, Clare Samantha; Anderson, Rebecca Anne; Kane, Robert Thomas; Finlay-Jones, Amy Louise
2016-07-05
The development and evaluation of Internet-delivered cognitive behavioral therapy (iCBT) interventions provides a potential solution for current limitations in the acceptability, availability, and accessibility of mental health care for young people with obsessive-compulsive disorder (OCD). Preliminary results support the effectiveness of therapist-assisted iCBT for young people with OCD; however, no previous studies have examined the effectiveness of completely self-guided iCBT for OCD in young people. We aimed to conduct a preliminary evaluation of the effectiveness of the OCD? Not Me! program for reducing OCD-related psychopathology in young people (12-18 years). This program is an eight-stage, completely self-guided iCBT treatment for OCD, which is based on exposure and response prevention. These data were early and preliminary results of a longer study in which an open trial design is being used to evaluate the effectiveness of the OCD? Not Me! Participants were required to have at least subclinical levels of OCD to be offered the online program. Participants with moderate-high suicide/self-harm risk or symptoms of eating disorder or psychosis were not offered the program. OCD symptoms and severity were measured at pre- and posttest, and at the beginning of each stage of the program. Data was analyzed using generalized linear mixed models. A total of 334 people were screened for inclusion in the study, with 132 participants aged 12 to 18 years providing data for the final analysis. Participants showed significant reductions in OCD symptoms (P<.001) and severity (P<.001) between pre- and posttest. These preliminary results suggest that fully automated iCBT holds promise as a way of increasing access to treatment for young people with OCD; however, further research needs to be conducted to replicate the results and to determine the feasibility of the program. Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12613000152729; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=363654 (Archived by WebCite at http://www.webcitation.org/ 6iD7EDFqH).
Anderson, Rebecca Anne; Kane, Robert Thomas; Finlay-Jones, Amy Louise
2016-01-01
Background The development and evaluation of Internet-delivered cognitive behavioral therapy (iCBT) interventions provides a potential solution for current limitations in the acceptability, availability, and accessibility of mental health care for young people with obsessive-compulsive disorder (OCD). Preliminary results support the effectiveness of therapist-assisted iCBT for young people with OCD; however, no previous studies have examined the effectiveness of completely self-guided iCBT for OCD in young people. Objective We aimed to conduct a preliminary evaluation of the effectiveness of the OCD? Not Me! program for reducing OCD-related psychopathology in young people (12-18 years). This program is an eight-stage, completely self-guided iCBT treatment for OCD, which is based on exposure and response prevention. Methods These data were early and preliminary results of a longer study in which an open trial design is being used to evaluate the effectiveness of the OCD? Not Me! program. Participants were required to have at least subclinical levels of OCD to be offered the online program. Participants with moderate-high suicide/self-harm risk or symptoms of eating disorder or psychosis were not offered the program. OCD symptoms and severity were measured at pre- and posttest, and at the beginning of each stage of the program. Data was analyzed using generalized linear mixed models. Results A total of 334 people were screened for inclusion in the study, with 132 participants aged 12 to 18 years providing data for the final analysis. Participants showed significant reductions in OCD symptoms (P<.001) and severity (P<.001) between pre- and posttest. Conclusions These preliminary results suggest that fully automated iCBT holds promise as a way of increasing access to treatment for young people with OCD; however, further research needs to be conducted to replicate the results and to determine the feasibility of the program. Trial Registration Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12613000152729; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=363654 (Archived by WebCite at http://www.webcitation.org/ 6iD7EDFqH) PMID:27381977
Tseng, Yu-Ting; Chang, Elizabeth H; Kuo, Li-Na; Shen, Wan-Chen; Bai, Kuan-Jen; Wang, Chih-Chi; Chen, Hsiang-Yin
2017-10-01
The PharmaCloud system, a cloud-based medication system, was launched by the Taiwan National Health Insurance Administration (NHIA) in 2013 to integrate patients' medication lists among different medical institutions. The aim of the preliminary study was to evaluate satisfaction with this system among physicians and pharmacists at the early stage of system implementation. A questionnaire was developed through a review of the literature and discussion in 6 focus groups to understand the level of satisfaction, attitudes, and intentions of physicians and pharmacists using the PharmaCloud system. It was then administered nationally in Taiwan in July to September 2015. Descriptive statistics and multiple regression were performed to identify variables influencing satisfaction and intention to use the system. In total, 895 pharmacist and 105 physician questionnaires were valid for analysis. The results showed that satisfaction with system quality warranted improvement. Positive attitudes toward medication reconciliation among physicians and pharmacists, which were significant predictors of the intention to use the system (β= 0.223, p < 0.001). Most physicians and pharmacists agreed that obtaining signed patient consent was needed but preferred that it be conducted by the NHIA rather than by individual medical institutions (4.02 ± 1.19 vs. 3.49 ± 1.40, p < 0.01). The preliminary study results indicated a moderate satisfaction toward the PharmaCloud system. Hospital pharmacists had a high satisfaction rate, but neither are physicians and community pharmacists. Continuously improvement on system quality has been performing based on the results of this preliminary survey. Policies and standardization processes, including privacy protection, are still warranted further actions to make the Taiwan PharmaCloud system a convenient platform for medication reconciliation. Copyright © 2017 Elsevier B.V. All rights reserved.
Utility of Social Modeling for Proliferation Assessment - Preliminary Assessment
DOE Office of Scientific and Technical Information (OSTI.GOV)
Coles, Garill A.; Gastelum, Zoe N.; Brothers, Alan J.
2009-06-01
This Preliminary Assessment draft report will present the results of a literature search and preliminary assessment of the body of research, analysis methods, models and data deemed to be relevant to the Utility of Social Modeling for Proliferation Assessment research. This report will provide: 1) a description of the problem space and the kinds of information pertinent to the problem space, 2) a discussion of key relevant or representative literature, 3) a discussion of models and modeling approaches judged to be potentially useful to the research, and 4) the next steps of this research that will be pursued based onmore » this preliminary assessment. This draft report represents a technical deliverable for the NA-22 Simulations, Algorithms, and Modeling (SAM) program. Specifically this draft report is the Task 1 deliverable for project PL09-UtilSocial-PD06, Utility of Social Modeling for Proliferation Assessment. This project investigates non-traditional use of social and cultural information to improve nuclear proliferation assessment, including nonproliferation assessment, proliferation resistance assessments, safeguards assessments and other related studies. These assessments often use and create technical information about the State’s posture towards proliferation, the vulnerability of a nuclear energy system to an undesired event, and the effectiveness of safeguards. This project will find and fuse social and technical information by explicitly considering the role of cultural, social and behavioral factors relevant to proliferation. The aim of this research is to describe and demonstrate if and how social science modeling has utility in proliferation assessment.« less
Dammeyer, Jesper; Køppe, Simo
2013-06-01
Research in social interaction and nonverbal communication among individuals with severe developmental disabilities also includes the study of body movements. Advances in analytical technology give new possibilities for measuring body movements more accurately and reliably. One such advance is the Qualisys Motion Capture System (QMCS), which utilizes optical markers to capture body movements. The aim of this study was to explore the practicality of measuring body movements in the nonverbal communication of a child with severe developmental disabilities. A preliminary case study has been undertaken. The social interaction between a boy with developmental disabilities and his teacher was analyzed (1) using observer ratings on psychological aspects of the social interaction and (2) measuring body positions, velocity, and angles of body movements using the QMCS. Associations between observer ratings and measured body movements were examined. This preliminary case study has indicated that emotional response and attention level during the social interaction corresponded with local, synchronized movements and face-to-face orientation. Measurement of motor behavior is suggested as being a potentially useful methodological approach to studying social interaction and communication development.
Cho, Hanna; Jeon, Seun; Kim, Changsoo; Ye, Byoung Seok; Kim, Geon Ha; Noh, Young; Kim, Hee Jin; Yoon, Cindy W; Kim, Yeo Jin; Kim, Jung-Hyun; Park, Sang Eon; Kim, Sung Tae; Lee, Jong-Min; Kang, Sue J; Suh, Mee Kyung; Chin, Juhee; Na, Duk L; Kang, Dae Ryong; Seo, Sang Won
2015-01-01
Epidemiological studies have reported that higher education (HE) is associated with a reduced risk of incident Alzheimer's disease (AD). However, after the clinical onset of AD, patients with HE levels show more rapid cognitive decline than patients with lower education (LE) levels. Although education level and cognition have been linked, there have been few longitudinal studies investigating the relationship between education level and cortical decline in patients with AD. The aim of this study was to compare the topography of cortical atrophy longitudinally between AD patients with HE (HE-AD) and AD patients with LE (LE-AD). We prospectively recruited 36 patients with early-stage AD and 14 normal controls. The patients were classified into two groups according to educational level, 23 HE-AD (>9 years) and 13 LE-AD (≤9 years). As AD progressed over the 5-year longitudinal follow-ups, the HE-AD showed a significant group-by-time interaction in the right dorsolateral frontal and precuneus, and the left parahippocampal regions compared to the LE-AD. Our study reveals that the preliminary longitudinal effect of HE accelerates cortical atrophy in AD patients over time, which underlines the importance of education level for predicting prognosis.
Construction Of Critical Thinking Skills Test Instrument Related The Concept On Sound Wave
NASA Astrophysics Data System (ADS)
Mabruroh, F.; Suhandi, A.
2017-02-01
This study aimed to construct test instrument of critical thinking skills of high school students related the concept on sound wave. This research using a mixed methods with sequential exploratory design, consists of: 1) a preliminary study; 2) design and review of test instruments. The form of test instruments in essay questions, consist of 18 questions that was divided into 5 indicators and 8 sub-indicators of the critical thinking skills expressed by Ennis, with questions that are qualitative and contextual. Phases of preliminary study include: a) policy studies; b) survey to the school; c) and literature studies. Phases of the design and review of test instruments consist of two steps, namely a draft design of test instruments include: a) analysis of the depth of teaching materials; b) the selection of indicators and sub-indicators of critical thinking skills; c) analysis of indicators and sub-indicators of critical thinking skills; d) implementation of indicators and sub-indicators of critical thinking skills; and e) making the descriptions about the test instrument. In the next phase of the review test instruments, consist of: a) writing about the test instrument; b) validity test by experts; and c) revision of test instruments based on the validator.
Feasibility study of a family-focused intervention to improve outcomes for children with FASD.
Reid, Natasha; Dawe, Sharon; Harnett, Paul; Shelton, Doug; Hutton, Lauren; O'Callaghan, Frances
2017-08-01
Growing evidence shows that children with fetal alcohol spectrum disorder (FASD) can benefit from interventions, and specifically interventions focused on improving self-regulation. However, novel ways of improving outcomes for children with FASD need further investigation so that programs target not only the individual child but also the family context, which includes the parent-child relationship. The current study aimed to evaluate the feasibility of an adapted version of the Parents under Pressure (PuP) program that addresses self-regulatory processes, through improving the parent-child relationship and the use of mindfulness-based strategies for both children and parents. This was a mixed methods study. Feasibility was examined by evaluating recruitment, data collection/outcome measures, and intervention procedures. The study used a phenomenological approach to obtain qualitative information from caregivers and a single-case experimental design to evaluate the preliminary participant responses to the intervention. Two out of three families completed treatment. The recruitment and intervention procedures were found to be suitable for and acceptable to the families involved. Some concerns were identified regarding the outcome measures that would need to be addressed in future research. Quantitative and qualitative outcomes were positive. The results provide preliminary support for the feasibility of an adapted version of the PuP program. Thus, offering a potential multi-component option, that aims to improve self-regulatory skills for children with FASD, through focusing on improving the parent-child relationship and incorporating mindfulness-based techniques for both parents and children. Copyright © 2017 Elsevier Ltd. All rights reserved.
Space transfer vehicle concepts and requirements study. Volume 3, book 1: Program cost estimates
NASA Technical Reports Server (NTRS)
Peffley, Al F.
1991-01-01
The Space Transfer Vehicle (STV) Concepts and Requirements Study cost estimate and program planning analysis is presented. The cost estimating technique used to support STV system, subsystem, and component cost analysis is a mixture of parametric cost estimating and selective cost analogy approaches. The parametric cost analysis is aimed at developing cost-effective aerobrake, crew module, tank module, and lander designs with the parametric cost estimates data. This is accomplished using cost as a design parameter in an iterative process with conceptual design input information. The parametric estimating approach segregates costs by major program life cycle phase (development, production, integration, and launch support). These phases are further broken out into major hardware subsystems, software functions, and tasks according to the STV preliminary program work breakdown structure (WBS). The WBS is defined to a low enough level of detail by the study team to highlight STV system cost drivers. This level of cost visibility provided the basis for cost sensitivity analysis against various design approaches aimed at achieving a cost-effective design. The cost approach, methodology, and rationale are described. A chronological record of the interim review material relating to cost analysis is included along with a brief summary of the study contract tasks accomplished during that period of review and the key conclusions or observations identified that relate to STV program cost estimates. The STV life cycle costs are estimated on the proprietary parametric cost model (PCM) with inputs organized by a project WBS. Preliminary life cycle schedules are also included.
Torres, Bárbara; Alonso-Arbiol, Itziar; Cantero, María José; Abubakar, Amina
2011-11-01
The quality of infant-mother attachment has been linked to competence in different domains of child development. Research indicates that early intervention can enhance the quality of infant-mother attachment, though its efficacy in a group format has yet to be evaluated. The current study is aimed at examining the usefulness of a group intervention in enhancing infant-mother attachment. An intervention aimed at addressing aspects such as maternal responsivity, sensitivity and childrearing behaviour was developed by the researchers and experienced psychologists. The intervention spanned a period of 14 months starting from the third quarter of pregnancy. The intervention was evaluated among 24 mothers from the Basque region of Spain. The sample consisted of children of both genders in a similar proportion: 45.8% were boys and 54.2% were girls. The children in this sample were full-term born and did not present symptoms of any serious pre- or postnatal complications. The intervention had a statistically non-significant medium effect. Infants whose mothers had received the intervention showed higher rates of secure attachment compared to children from the control group, as assessed by the Strange Situation observation procedure. A potentially significant confounding variable, maternal attachment, was balanced across the intervention and comparison groups. We can tentatively point out that a group intervention may enhance the quality of infant-mother attachment. Nevertheless, because the study design was not randomized, the results of this study remain preliminary and need replication in a full randomized controlled trial designed study.
2017-07-01
Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to any penalty for failing to comply with a...progress in our work with the industry collaborator providing data to meet our study aims. Preliminary analyses of sleep and cognitive performance data...have yielded compelling findings with respect to sleep duration and cognitive performance across the lifespan. These now published findings
Stability of facial emotion recognition performance in bipolar disorder.
Martino, Diego J; Samamé, Cecilia; Strejilevich, Sergio A
2016-09-30
The aim of this study was to assess the performance in emotional processing over time in a sample of euthymic patients with bipolar disorder (BD). Performance in the facial recognition of the six basic emotions (surprise, anger, sadness, happiness, disgust, and fear) did not change during a follow-up period of almost 7 years. These preliminary results suggest that performance in facial emotion recognition might be stable over time in BD. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Atmosphere Behavior in Gas-Closed Mouse-Algal Systems: An Experimental and Modelling Study
NASA Technical Reports Server (NTRS)
Averner, M. M.; Moore, B., III; Bartholomew, I.; Wharton, R.
1985-01-01
A dual approach of mathematical modelling and laboratory experimentation aimed at examining the gas exchange characteristics of artificial animal/plant systems closed to the ambient atmosphere was initiated. The development of control techniques and management strategies for maintaining the atmospheric levels of carbon dioxide and oxygen at physiological levels is examined. A mathematical model simulating the atmospheric behavior in these systems was developed and an experimental gas closed system was constructed. These systems are described and preliminary results are presented.
New results of Δσ L( np) at high energies
NASA Astrophysics Data System (ADS)
Sharov, V. I.; Adiasevich, B. P.; Anischenko, N. G.; Antonenko, V. G.; Averichev, S. A.; Azhgirey, L. S.; Bartenev, V. D.; Bazhanov, N. A.; Belyaev, A. A.; Blinov, N. A.; Borisov, N. S.; Borzakov, S. B.; Borzunov, Yu. T.; Bushuev, Yu. P.; Chernenko, L. P.; Chernykh, E. V.; Chumakov, V. F.; Dolgh, S. A.; Fedorov, A. N.; Fimushkin, V. V.; Finger, M.; Finger, M.; Golovanov, L. B.; Gurevich, G. M.; Janata, A.; Kirillov, A. D.; Kolomiets, V. G.; Komogorov, E. V.; Kopylov, S. A.; Kovalenko, A. D.; Kovalev, A. I.; Krasnov, V. A.; Krstonoshich, P.; Kuzmin, E. S.; Ladygin, V. P.; Lazarev, A. B.; Lehar, F.; de Lesquen, A.; Liburg, M. Yu.; Livanov, A. N.; Lukhanin, A. A.; Maniakov, P. K.; Matafonov, V. N.; Matyushevsky, E. A.; Moroz, V. D.; Morozov, A. A.; Neganov, A. B.; Nikolaevsky, G. P.; Nomofilov, A. A.; Panteleev, Tz.; Pilipenko, Yu. K.; Pisarev, I. L.; Plis, Yu. A.; Polunin, Yu. P.; Prokofiev, A. N.; Prytkov, V. Yu.; Rukoyatkin, P. A.; Schedrov, V. A.; Schevelev, O. N.; Shilov, S. N.; Shishov, Yu. A.; Shutov, V. B.; Slunečka, M.; Slunečková, V.; Starikov, A. Yu.; Stoletov, G. D.; Strunov, L. N.; Svetov, A. L.; Usov, Yu. A.; Vasiliev, T.; Volkov, V. I.; Vorobiev, E. I.; Yudin, I. P.; Zaitsev, I. V.; Zhdanov, A. A.; Zhmyrov, V. N.
2002-03-01
Preliminary results of the Δσ L( np) at 1.4, 1.7, 1.9 and 2.0 GeV are presented. They were obtained during the two data-taking runs at the JINR Dubna Synchrophasotron in 2001 and complete the existing data above 1.1 GeV. The data analysis is in progress. The aim of the present studies is to determine the imaginary and real parts of the np spin-dependent forward scattering amplitudes over this energy range.
NASA Astrophysics Data System (ADS)
Curci, Vita; Dassisti, Michele; Josefa, Mula Bru; Manuel, Díaz Madroñero
2014-10-01
Supply chain model (SCM) are potentially capable to integrate different aspects in supporting decision making for enterprise management tasks. The aim of the paper is to propose an hybrid mathematical programming model for optimization of production requirements resources planning. The preliminary model was conceived bottom-up from a real industrial case analysed oriented to maximize cash flow. Despite the intense computational effort required to converge to a solution, optimisation done brought good result in solving the objective function.
Shock Tunnel Studies of Scramjet Phenomena
NASA Technical Reports Server (NTRS)
Stalker, R. J.
1996-01-01
Work focussed on a large number of preliminary studies of supersonic combustion in a simple combustion duct - thrust nozzle combination, investigating effects of Mach number, equivalence ratio, combustor divergence, fuel injecting angle and other parameters with an influence on the combustion process. This phase lasted for some three or four years, during which strongest emphasis was placed on responding to the request for preliminary experimental information on high enthalpy effects, to support the technology maturation activities of the NASP program. As the need for preliminary data became less urgent, it was possible to conduct more systematic studies of high enthalpy combustion phenomena, and to initiate other projects aimed at improving the facilities and instrumentation used for studying scramjet phenomena at high enthalpies. The combustion studies were particularly directed towards hypersonic combustion, and to the effects of injecting fuel along the combustion chamber wall. A substantial effort was directed towards a study of the effect of scale on the supersonic combustion process. The influence of wave phenomena (both compression waves and expansion waves) on the realization of thrust from a supersonic combustion process was also investigated. The effect of chemical kinetics was looked into, particularly as it affected the composition of the test flow provided by a ground facility. The effect of injection of the fuel through wall orifices was compared with injection from a strut spanning the stream, and the effect of heating the fuel prior to injection was investigated. Studies of fuel-air mixing by shock impingement were also done, as well as mass spectrometer surveys of a combustion wake. The use of hypersonic nozzles with an expansion tube was investigated. A new method was developed for measuring the forces acting of a model in less than one millisecond. Also included in this report are listings of published journal papers and conference presentations.
Impact of organizational policies and practices on workplace injuries in a hospital setting.
Tveito, T H; Sembajwe, G; Boden, L I; Dennerlein, J T; Wagner, G R; Kenwood, C; Stoddard, A M; Reme, S E; Hopcia, K; Hashimoto, D; Shaw, W S; Sorensen, G
2014-08-01
This study aimed to assess relationships between perceptions of organizational practices and policies (OPP), social support, and injury rates among workers in hospital units. A total of 1230 hospital workers provided survey data on OPP, job flexibility, and social support. Demographic data and unit injury rates were collected from the hospitals' administrative databases. Injury rates were lower in units where workers reported higher OPP scores and high social support. These relationships were mainly observed among registered nurses. Registered nurses perceived coworker support and OPP as less satisfactory than patient care associates (PCAs). Nevertheless, because of the low number of PCAs at each unit, results for the PCAs are preliminary and should be further researched in future studies with larger sample sizes. Employers aiming to reduce injuries in hospitals could focus on good OPP and supportive work environment.
Preliminary consideration of CFETR ITER-like case diagnostic system.
Li, G S; Yang, Y; Wang, Y M; Ming, T F; Han, X; Liu, S C; Wang, E H; Liu, Y K; Yang, W J; Li, G Q; Hu, Q S; Gao, X
2016-11-01
Chinese Fusion Engineering Test Reactor (CFETR) is a new superconducting tokamak device being designed in China, which aims at bridging the gap between ITER and DEMO, where DEMO is a tokamak demonstration fusion reactor. Two diagnostic cases, ITER-like case and towards DEMO case, have been considered for CFETR early and later operating phases, respectively. In this paper, some preliminary consideration of ITER-like case will be presented. Based on ITER diagnostic system, three versions of increased complexity and coverage of the ITER-like case diagnostic system have been developed with different goals and functions. Version A aims only machine protection and basic control. Both of version B and version C are mainly for machine protection, basic and advanced control, but version C has an increased level of redundancy necessary for improved measurements capability. The performance of these versions and needed R&D work are outlined.
Preliminary consideration of CFETR ITER-like case diagnostic system
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li, G. S.; Liu, Y. K.; Gao, X.
2016-11-15
Chinese Fusion Engineering Test Reactor (CFETR) is a new superconducting tokamak device being designed in China, which aims at bridging the gap between ITER and DEMO, where DEMO is a tokamak demonstration fusion reactor. Two diagnostic cases, ITER-like case and towards DEMO case, have been considered for CFETR early and later operating phases, respectively. In this paper, some preliminary consideration of ITER-like case will be presented. Based on ITER diagnostic system, three versions of increased complexity and coverage of the ITER-like case diagnostic system have been developed with different goals and functions. Version A aims only machine protection and basicmore » control. Both of version B and version C are mainly for machine protection, basic and advanced control, but version C has an increased level of redundancy necessary for improved measurements capability. The performance of these versions and needed R&D work are outlined.« less
Susko, Michele L; Bloom, Michael S; Neamtiu, Iulia A; Appleton, Allison A; Surdu, Simona; Pop, Cristian; Fitzgerald, Edward F; Anastasiu, Doru; Gurzau, Eugen S
2017-04-01
High level arsenic exposure is associated with reproductive toxicity in experimental and observational studies; however, few data exist to assess risks at low levels. Even less data are available to evaluate the impact of low level arsenic exposure on human fecundity. Our aim in this pilot study was a preliminary evaluation of associations between low level drinking water arsenic contamination and female fecundity. This retrospective study was conducted among women previously recruited to a hospital-based case-control study of spontaneous pregnancy loss in Timiṣ County, Romania. Women (n=94) with planned pregnancies of 5-20 weeks gestation completed a comprehensive physician-administered study questionnaire and reported the number of menstrual cycles attempting to conceive as the time to pregnancy (TTP). Drinking water samples were collected from residential drinking water sources and we determined arsenic levels using hydride generation-atomic absorption spectrometry (HG-AAS). Multivariable Cox-proportional hazards regression with Efron approximation was employed to evaluate TTP as a function of drinking water arsenic concentrations among planned pregnancies, adjusted for covariates. There was no main effect for drinking water arsenic exposure, yet the conditional probability for pregnancy was modestly lower among arsenic exposed women with longer TTPs, relative to women with shorter TTPs, and relative to unexposed women. For example, 1µg/L average drinking water arsenic conferred 5%, 8%, and 10% lower likelihoods for pregnancy in the 6th, 9th, and 12th cycles, respectively (P=0.01). While preliminary, our results suggest that low level arsenic contamination in residential drinking water sources may further impair fecundity among women with longer waiting times; however, this hypothesis requires confirmation by a future, more definitive study. Copyright © 2016 Elsevier Inc. All rights reserved.
Susko, Michele L.; Bloom, Michael S.; Neamtiu, Iulia A.; Appleton, Allison A.; Surdu, Simona; Pop, Cristian; Fitzgerald, Edward F.; Anastasiu, Doru; Gurzau, Eugen S.
2017-01-01
High level arsenic exposure is associated with reproductive toxicity in experimental and observational studies; however, few data exist to assess risks at low levels. Even less data are available to evaluate the impact of low level arsenic exposure on human fecundity. Our aim in this pilot study was a preliminary evaluation of associations between low level drinking water arsenic contamination and female fecundity. This retrospective study was conducted among women previously recruited to a hospital-based case-control study of spontaneous pregnancy loss in Timiş County, Romania. Women (n = 94) with planned pregnancies of 5–20 weeks gestation completed a comprehensive physician-administered study questionnaire and reported the number of menstrual cycles attempting to conceive as the time to pregnancy (TTP). Drinking water samples were collected from residential drinking water sources and we determined arsenic levels using hydride generation-atomic absorption spectrometry (HG-AAS). Multivariable Cox-proportional hazards regression with Efron approximation was employed to evaluate TTP as a function of drinking water arsenic concentrations among planned pregnancies, adjusted for covariates. There was no main effect for drinking water arsenic exposure, yet the conditional probability for pregnancy was modestly lower among arsenic exposed women with longer TTPs, relative to women with shorter TTPs, and relative to unexposed women For example, 1 μg/L average drinking water arsenic conferred 5%, 8%, and 10% lower likelihoods for pregnancy in the 6th, 9th, and 12th cycles, respectively (P = 0.01). While preliminary, our results suggest that low level arsenic contamination in residential drinking water sources may further impair fecundity among women with longer waiting times; however, this hypothesis requires confirmation by a future, more definitive study. PMID:28061371
Kelly-Cirino, Cassandra D; Curry, Patricia S; Marola, Jamie L; Helstrom, Niels K; Salfinger, Max
2016-11-01
OMNIgene®•SPUTUM (OM-S) is a sputum transport reagent designed to work with all tuberculosis diagnostics and eliminate the need for cold chain. The aim of this preliminary study was to assess the compatibility of OM-S-treated sputum with the Xpert® MTB/RIF assay. Fifty-five characterized sputa from the FIND TB Specimen Bank were used. Compatibility of OM-S was assessed for both Xpert sample preparation methods: H.1 protocol (sediment, n=25) and H.2 protocol (direct expectorate, n=30). All controls were prepared using the H.2 protocol. Results revealed 100% concordance of MTB/RIF results for all except the low-positive group in the H.1 study arm (n=10; 88% concordance). OM-S-treated sputa were successful in both protocols; if the Xpert buffer is not added during the H.2 procedure, sample viscosity may require repeat testing. Using OM-S could offer users flexibility in clinical testing algorithms. Larger compatibility studies are warranted, particularly with respect to MTB/RIF results for low-positive samples. Copyright © 2016 Elsevier Inc. All rights reserved.
Illuminati, I; Seigle-Murandi, F; Gouzou, S; Fabacher, T; Facca, S; Hidalgo Diaz, J J; Liverneaux, P
2017-12-01
There are no published studies on the management of carpal tunnel syndrome (CTS) patients who have already been operated for recurrent CTS on the contralateral side. The aim of this study was to evaluate 13 patients with CTS who underwent primary release using a Canaletto ® implant. The 13 patients had all been operated for recurrent CTS previously. On the contralateral side, they all had subjective signs, and two of them already had complications. All were operated with the Canaletto ® implant according to Duché's technique, in a mean of 20minutes. After a mean 19.3-month follow-up, paresthesia, pain, and QuickDASH scores were significantly improved, even in one patient who underwent revision at another facility. This preliminary study suggests that use of a Canaletto ® implant as first-line treatment for CTS in patients who already underwent revision surgery on the other side is a simple and safe technique, without worsening of symptoms. These findings should be assessed with a prospective randomized controlled trial. Copyright © 2017 SFCM. Published by Elsevier Masson SAS. All rights reserved.
Preliminary results of the aerosol optical depth retrieval in Johor, Malaysia
NASA Astrophysics Data System (ADS)
Lim, H. Q.; Kanniah, K. D.; Lau, A. M. S.
2014-02-01
Monitoring of atmospheric aerosols over the urban area is important as tremendous amounts of pollutants are released by industrial activities and heavy traffic flow. Air quality monitoring by satellite observation provides better spatial coverage, however, detailed aerosol properties retrieval remains a challenge. This is due to the limitation of aerosol retrieval algorithm on high reflectance (bright surface) areas. The aim of this study is to retrieve aerosol optical depth over urban areas of Iskandar Malaysia; the main southern development zone in Johor state, using Moderate Resolution Imaging Spectroradiometer (MODIS) 500 m resolution data. One of the important steps is the aerosol optical depth retrieval is to characterise different types of aerosols in the study area. This information will be used to construct a Look Up Table containing the simulated aerosol reflectance and corresponding aerosol optical depth. Thus, in this study we have characterised different aerosol types in the study area using Aerosol Robotic Network (AERONET) data. These data were processed using cluster analysis and the preliminary results show that the area is consisting of coastal urban (65%), polluted urban (27.5%), dust particles (6%) and heavy pollution (1.5%) aerosols.
A Study of Imaging Interferometer Simulators
NASA Technical Reports Server (NTRS)
Allen, Ronald J.
2002-01-01
Several new space science mission concepts under development at NASA-GSFC for astronomy are intended to carry out synthetic imaging using Michelson interferometers or direct (Fizeau) imaging with sparse apertures. Examples of these mission concepts include the Stellar Imager (SI), the Space Infrared Interferometric Telescope (SPIRIT), the Submillimeter Probe of the Evolution of Cosmic Structure (SPECS), and the Fourier-Kelvin Stellar Interferometer (FKSI). We have been developing computer-based simulators for these missions. These simulators are aimed at providing a quantitative evaluation of the imaging capabilities of the mission by modelling the performance on different realistic targets in terms of sensitivity, angular resolution, and dynamic range. Both Fizeau and Michelson modes of operation can be considered. Our work is based on adapting a computer simulator called imSIM, which was initially written for the Space Interferometer Mission in order to simulate the imaging mode of new missions such as those listed. In a recent GSFC-funded study we have successfully written a preliminary version of a simulator SISIM for the Stellar Imager and carried out some preliminary studies with it. In a separately funded study we have also been applying these methods to SPECS/SPIRIT.
Parisien, Rachel B; Gillanders, Kirstie; Hennessy, Erin K; Herterich, Lisa; Saunders, Kendra; Lati, Jamil; Dos Santos, Stephanie; Hassall, Alison; O'Brien, Kelly K
2016-05-31
The aim of this study was to conduct a preliminary investigation into parents' experiences of physical therapy and early mobility (EM) for their children in a pediatric critical care unit (PCCU). We conducted a series of four qualitative case studies using in-depth semi-structured face-to-face interviews. We recruited parents of children who had undergone surgery and received at least one EM physical therapy intervention while intubated. We conducted a thematic analysis of transcribed interviews to illuminate the factors that influenced EM experiences. Four parents participated in the study. We developed an overview of Parental Experiences with Physical Therapy and Early Mobility in a PCCU, which includes four themes that parents believed influenced their experiences: (1) environmental factors; (2) awareness of physical therapist and health care professional (HCP) roles; (3) communication among parents and HCPs; and (4) parental participation in their child's EM, within the overarching parental experiences in the PCCU. This study affords a preliminary understanding of parents' experiences with physical therapy and EM in a PCCU setting. Results provide an important foundation for future research on mobility in the context of pediatric critical care research and practice.
Developing Ill-defined problem-solving for the context of “South Sumatera”
NASA Astrophysics Data System (ADS)
Arifin, S.; Zulkardi; Putri, R. I. I.; Hartono, Y.; Susanti, E.
2017-12-01
This study aims to produce a valid and practical ill-defined problem-solving for context South Sumatera. The subject of the research is three students of the first semester of undergraduate students in the mathematics department of Raden Fatah State Islamic University. This study use development studies that consist of preliminary and prototyping. In preliminary stage have been analysis content curricula, indicator, and strategies of problem-solving. Meanwhile, in prototyping stage only consist of self-evaluation, expert review, and one-to-one. The data were collected through a walkthrough, interview, and test. The data were validated using expert review, but in practice, the data were obtained from test and interview to subject of the research. This studies produced two valid and practical problem-solving. The first problem is about “Benteng Kuto Besak”, and the second problem is about “Monpera”. From the expert review, the conclusion can be drawn that two problems which are developing are ill-defined problem-solving, and valid from content, construct, and its language. Besides that, the problems are practical because all students know and understand what the problems goal, but not the solutions.
A techno-economic approach to plasma gasification
NASA Astrophysics Data System (ADS)
Ramos, Ana; Rouboa, Abel
2018-05-01
Within the most used Waste-to-Energy technologies plasma gasification is recent and therefore not yet widely commercialized. Thus, it is necessary to conduct a viability study to support the thorough understanding and implementation of this thermal treatment. This paper aims to assess some technical, environmental and economic aspects of plasma gasification paving the way for a more sustained waste management system, as well as taking advantage of the commodity assets granted by the technique. Therefore, results from previously published studies were updated and highlighted as a preliminary starting point in order to potentially evolve to a complete and systematic work.
Schiro, Jessica; Marcilly, Romaric; Leroy, Nicolas; Wawrzyniak, Clément; Martinot, Alain; Pelayo, Sylvia
2015-01-01
The study aims to identify the information useful to support a patients' EDs' choice in order to design a patient Web-based system. For that purpose, a focus group and a formative user test have been performed. The results show that five types of information can be relevant. The spontaneous favored information is the "distance" to EDs. The "Wait time", that is sanctified in literature, is only used in a second time. A larger summative evaluation should be planned to evaluate and validate the befits of this kind of tool.
Ageing Studies on the First Resistive-MicroMeGaS Quadruplet at GIF++ Preliminary Results
NASA Astrophysics Data System (ADS)
Alvarez Gonzalez, B.; Bianco, M.; Farina, E.; Iengo, P.; Kuger, F.; Lin, T.; Longo, L.; Sekhniaidze, G.; Sidiropoulou, O.; Schott, M.; Valderanis, C.; Wotschack, J.
2018-02-01
A resistive-MicroMeGaS quadruplet built at CERN has been installed at the new CERN Gamma Irradiation Facility (GIF++) with the aim of carrying out a long-term ageing study. Two smaller resistive bulk-MicroMeGaS produced at the CERN PCB workshop have also been installed at GIF++ in order to provide a comparison of the ageing behavior with the MicroMeGaS quadruplet. We give an overview of the ongoing tests at GIF++ in terms of particle rate, integrated charge and spatial resolution of the MicroMeGaS detectors.
Leelarungrayub, Jirakrit; Yankai, Araya; Pinkaew, Decha; Puntumetakul, Rungthip; Laskin, James J; Bloomer, Richard J
2016-01-01
The aims of this preliminary study were to evaluate the antioxidant and lipid status before and after star fruit juice consumption in healthy elderly subjects, and the vitamins in star fruit extracts. A preliminary designated protocol was performed in 27 elderly individuals with a mean (±SD) age of 69.5±5.3 years, by planning a 2-week control period before 4 weeks of consumption of star fruit twice daily. Oxidative stress parameters such as total antioxidant capacity, glutathione, malondialdehyde, protein hydroperoxide, multivitamins such as l-ascorbic acid (Vit C), retinoic acid (Vit A), and tocopherol (Vit E), and the lipid profile parameters such as cholesterol, triglyceride, high-density lipoprotein-cholesterol (HDL-C) and low-density lipoprotein-cholesterol (LDL-C) were analyzed. Moreover, Vit C, Vit A, and Vit E levels were evaluated in the star fruit extracts during the 4-week period. In the 2-week control period, all parameters showed no statistically significant difference; after 4 weeks of consumption, significant improvement in the antioxidant status was observed with increased total antioxidant capacity and reduced malondialdehyde and protein hydroperoxide levels, as well as significantly increased levels of Vit C and Vit A, when compared to the two-time evaluation during the baseline periods. However, glutathione and Vit E showed no statistical difference. In addition, the HDL-C level was higher and the LDL-C level was significantly lower when compared to both baseline periods. But the levels of triglyceride and cholesterol showed no difference. Vit C and Vit A were identified in small quantities in the star fruit extract. This preliminary study suggested that consumption of star fruit juice twice daily for 1 month improved the elderly people's antioxidant status and vitamins, as well as improved the lipoproteins related to Vit C and Vit A in the star fruit extract.
Leelarungrayub, Jirakrit; Yankai, Araya; Pinkaew, Decha; Puntumetakul, Rungthip; Laskin, James J; Bloomer, Richard J
2016-01-01
Objective The aims of this preliminary study were to evaluate the antioxidant and lipid status before and after star fruit juice consumption in healthy elderly subjects, and the vitamins in star fruit extracts. Methods A preliminary designated protocol was performed in 27 elderly individuals with a mean (±SD) age of 69.5±5.3 years, by planning a 2-week control period before 4 weeks of consumption of star fruit twice daily. Oxidative stress parameters such as total antioxidant capacity, glutathione, malondialdehyde, protein hydroperoxide, multivitamins such as l-ascorbic acid (Vit C), retinoic acid (Vit A), and tocopherol (Vit E), and the lipid profile parameters such as cholesterol, triglyceride, high-density lipoprotein-cholesterol (HDL-C) and low-density lipoprotein-cholesterol (LDL-C) were analyzed. Moreover, Vit C, Vit A, and Vit E levels were evaluated in the star fruit extracts during the 4-week period. Results In the 2-week control period, all parameters showed no statistically significant difference; after 4 weeks of consumption, significant improvement in the antioxidant status was observed with increased total antioxidant capacity and reduced malondialdehyde and protein hydroperoxide levels, as well as significantly increased levels of Vit C and Vit A, when compared to the two-time evaluation during the baseline periods. However, glutathione and Vit E showed no statistical difference. In addition, the HDL-C level was higher and the LDL-C level was significantly lower when compared to both baseline periods. But the levels of triglyceride and cholesterol showed no difference. Vit C and Vit A were identified in small quantities in the star fruit extract. Conclusion This preliminary study suggested that consumption of star fruit juice twice daily for 1 month improved the elderly people’s antioxidant status and vitamins, as well as improved the lipoproteins related to Vit C and Vit A in the star fruit extract. PMID:27621606
Lim, Jung-Won
2015-01-01
The present study aimed to examine the relationships among barriers to cancer care, perceived social support, and patient navigation services (PNS) for Korean breast cancer patients. For Korean breast cancer patients, PNS are comprised of five services, including emotional, financial, information, transportation, and disease management. The study findings demonstrated that transportation and disease management barriers were directly associated with PNS, whereas emotional and financial barriers were indirectly associated with PNS through perceived social support. The current study provides a preliminary Korean patient navigation model to identify how barriers to cancer care can be reduced through social support and PNS.
A Preliminary Rhetoric of Technical Copywriting.
ERIC Educational Resources Information Center
Henson, Leigh
1994-01-01
Discusses the rhetorical elements of technical copywriting, including its shared communicative aims with technical writing; authorship considerations such as ethics, education, and professionalism; and the concerns of promotional strategy, audience analysis, choice of media and materials, writing strategy, and style. (SR)
NASA Astrophysics Data System (ADS)
Suzuki, Yusuke; Maruo, Katsuhiko; Zhang, Alice W.; Shimogaki, Kazushige; Ogawa, Hideto; Hirayama, Fumiya
2012-01-01
Bacterial contamination of blood products is one of the most frequent infectious complications of transfusion. Since glucose levels in blood supplies decrease as bacteria proliferate, it should be possible to detect the presence of bacterial contamination by measuring the glucose concentrations in the blood components. Hence this study is aimed to serve as a preliminary study for the nondestructive measurement of glucose level in transfusion blood. The glucose concentrations in red blood cell (RBC) samples were predicted using near-infrared diffuse-reflectance spectroscopy in the 1350 to 1850 nm wavelength region. Furthermore, the effects of donor, hematocrit level, and temperature variations among the RBC samples were observed. Results showed that the prediction performance of a dataset which contained samples that differed in all three parameters had a standard error of 29.3 mg/dL. Multiplicative scatter correction (MSC) preprocessing method was also found to be effective in minimizing the variations in scattering patterns created by various sample properties. The results suggest that the diffuse-reflectance spectroscopy may provide another avenue for the detection of bacterial contamination in red cell concentrations (RCC) products.
Hepark, Sevket; Janssen, Lotte; de Vries, Alicia; Schoenberg, Poppy L A; Donders, Rogier; Kan, Cornelis C; Speckens, Anne E M
2015-11-20
The aim of this study was to examine the effectiveness of mindfulness as a treatment for adults diagnosed with ADHD. A 12-week-adapted mindfulness-based cognitive therapy (MBCT) program is compared with a waiting list (WL) group. Adults with ADHD were randomly allocated to MBCT (n = 55) or waitlist (n = 48). Outcome measures included investigator-rated ADHD symptoms (primary), self-reported ADHD symptoms, executive functioning, depressive and anxiety symptoms, patient functioning, and mindfulness skills. MBCT resulted in a significant reduction of ADHD symptoms, both investigator-rated and self-reported, based on per-protocol and intention-to-treat analyses. Significant improvements in executive functioning and mindfulness skills were found. Additional analyses suggested that the efficacy of MBCT in reducing ADHD symptoms and improving executive functioning is partially mediated by an increase in the mindfulness skill "Act With Awareness." No improvements were observed for depressive and anxiety symptoms, and patient functioning. This study provides preliminary support for the effectiveness of MBCT for adults with ADHD. © The Author(s) 2015.
Panerai, Simonetta; Tasca, Domenica; Lanuzza, Bartolo; Trubia, Grazia; Ferri, Raffaele; Musso, Sabrina; Alagona, Giovanna; Di Guardo, Giuseppe; Barone, Concetta; Gaglione, Maria P; Elia, Maurizio
2014-08-01
This report, based on four studies with children with low-functioning autism, aimed at evaluating the effects of repetitive transcranial magnetic stimulation delivered on the left and right premotor cortices on eye-hand integration tasks; defining the long-lasting effects of high-frequency repetitive transcranial magnetic stimulation; and investigating the real efficacy of high-frequency repetitive transcranial magnetic stimulation by comparing three kinds of treatments (high-frequency repetitive transcranial magnetic stimulation, a traditional eye-hand integration training, and both treatments combined). Results showed a significant increase in eye-hand performances only when high-frequency repetitive transcranial magnetic stimulation was delivered on the left premotor cortex; a persistent improvement up to 1 h after the end of the stimulation; better outcomes in the treatment combining high-frequency repetitive transcranial magnetic stimulation and eye-hand integration training. Based on these preliminary findings, further evaluations on the usefulness of high-frequency repetitive transcranial magnetic stimulation in rehabilitation of children with autism are strongly recommended. © The Author(s) 2013.
Mridula, Meenu R; Nair, Ashalatha S; Kumar, K Satheesh
2018-02-01
In this paper, we compared the efficacy of observation based modeling approach using a genetic algorithm with the regular statistical analysis as an alternative methodology in plant research. Preliminary experimental data on in vitro rooting was taken for this study with an aim to understand the effect of charcoal and naphthalene acetic acid (NAA) on successful rooting and also to optimize the two variables for maximum result. Observation-based modelling, as well as traditional approach, could identify NAA as a critical factor in rooting of the plantlets under the experimental conditions employed. Symbolic regression analysis using the software deployed here optimised the treatments studied and was successful in identifying the complex non-linear interaction among the variables, with minimalistic preliminary data. The presence of charcoal in the culture medium has a significant impact on root generation by reducing basal callus mass formation. Such an approach is advantageous for establishing in vitro culture protocols as these models will have significant potential for saving time and expenditure in plant tissue culture laboratories, and it further reduces the need for specialised background.
Fedele, David A; Mullins, Larry L; Wolfe-Christensen, Cortney; Carpentier, Melissa Y
2011-04-01
This preliminary investigation aimed to longitudinally examine parenting capacity variables, namely parental overprotection, perceived child vulnerability, and parenting stress and their relation to child adjustment in mothers of children on treatment for cancer. As part of a larger study, biological mothers (N=22) completed measures of parental overprotection, perceived child vulnerability, parenting stress, and child adjustment at Time 1 and a follow-up time point. Analyses were conducted to determine whether (1) levels of parental overprotection, perceived child vulnerability, and parenting stress declined from Time 1 to follow-up and (2) if Time 1 parenting capacity variables were associated with child adjustment at follow-up. Results revealed that parental overprotection, perceived child vulnerability, and parenting stress declined from Time 1 to follow-up, and levels of parental overprotection, perceived child vulnerability, and parenting stress at Time 1 were significantly related to child adjustment at follow-up. Collectively, the preliminary findings of this study indicate that mothers of children with cancer evidence improved parenting capacity over time. Furthermore, it seems that Time 1 parenting capacity variables are significantly related to later child adjustment.
Giannini, Giuseppe; Vesci, Loredana; Battistuzzi, Gianfranco; Vignola, Davide; Milazzo, Ferdinando M; Guglielmi, Mario Berardino; Barbarino, Marcella; Santaniello, Mosè; Fantò, Nicola; Mor, Marco; Rivara, Silvia; Pala, Daniele; Taddei, Maurizio; Pisano, Claudio; Cabri, Walter
2014-10-23
A systematic study of medicinal chemistry aimed at identifying a new generation of HDAC inhibitors, through the introduction of a thiol zinc-binding group (ZBG) and of an amide-lactam in the ω-position of the polyethylene chain of the vorinostat scaffold, allowed the selection of a new class of potent pan-HDAC inhibitors (pan-HDACis). Simple, highly versatile, and efficient synthetic approaches were used to synthesize a library of these new derivatives, which were then submitted to a screening for HDAC inhibition as well as to a preliminary in vitro assessment of their antiproliferative activity. Molecular docking into HDAC crystal structures suggested a binding mode for these thiol derivatives consistent with the stereoselectivity observed upon insertion of amide-lactam substituents in the ω-position. ST7612AA1 (117), selected as a drug candidate for further development, showed an in vitro activity in the nanomolar range associated with a remarkable in vivo antitumor activity, highly competitive with the most potent HDAC inhibitors, currently under clinical trials. A preliminary study of PK and metabolism is also illustrated.
Submovement control processes in discrete aiming as a function of space-time constraints.
Hsieh, Tsung-Yu; Liu, Yeou-Teh; Newell, Karl M
2017-01-01
There is preliminary evidence that there are several types of submovements in movement aiming that reflect different processes of control and can result from particular task constraints. The purpose of the study was to investigate the effect of movement space and time task criteria on the prevalence of different submovement control characteristics in discrete aiming. Twelve participants completed 3 distance x 5 time conditions each with 100 trials in a target-aiming movement task. The kinematic structure of the trajectory determined the prevalence of 5 submovement types (none; pre-peak, post-peak movement velocity; undershoot, overshoot). The findings showed that the overall number of submovements increased in the slower space-time conditions and was predominantly characterized by post-peak trajectory submovements rather than discrete overshoot submovements. Overshoot submovements were more frequent in the high average movement velocity and short time duration conditions. We concluded that there are qualitatively different distributional patterns of submovement types in discrete aiming tasks that are organized by the quantitative scaling of the average movement velocity arising from multiple control processes to meet the specific space-time task constraints.
Overnight shift work: factors contributing to diagnostic discrepancies.
Hanna, Tarek N; Loehfelm, Thomas; Khosa, Faisal; Rohatgi, Saurabh; Johnson, Jamlik-Omari
2016-02-01
The aims of the study are to identify factors contributing to preliminary interpretive discrepancies on overnight radiology resident shifts and apply this data in the context of known literature to draw parallels to attending overnight shift work schedules. Residents in one university-based training program provided preliminary interpretations of 18,488 overnight (11 pm–8 am) studies at a level 1 trauma center between July 1, 2013 and December 31, 2014. As part of their normal workflow and feedback, attendings scored the reports as major discrepancy, minor discrepancy, agree, and agree--good job. We retrospectively obtained the preliminary interpretation scores for each study. Total relative value units (RVUs) per shift were calculated as an indicator of overnight workload. The dataset was supplemented with information on trainee level, number of consecutive nights on night float, hour, modality, and per-shift RVU. The data were analyzed with proportional logistic regression and Fisher's exact test. There were 233 major discrepancies (1.26 %). Trainee level (senior vs. junior residents; 1.08 vs. 1.38 %; p < 0.05) and modality were significantly associated with performance. Increased workload affected more junior residents' performance, with R3 residents performing significantly worse on busier nights. Hour of the night was not significantly associated with performance, but there was a trend toward best performance at 2 am, with subsequent decreased accuracy throughout the remaining shift hours. Improved performance occurred after the first six night float shifts, presumably as residents acclimated to a night schedule. As overnight shift work schedules increase in popularity for residents and attendings, focused attention to factors impacting interpretative accuracy is warranted.
Peyron, Pierre-Antoine; Baccino, Éric; Nagot, Nicolas; Lehmann, Sylvain; Delaby, Constance
2017-02-01
Determination of skin wound vitality is an important issue in forensic practice. No reliable biomarker currently exists. Quantification of inflammatory cytokines in injured skin with MSD ® technology is an innovative and promising approach. This preliminary study aims to develop a protocol for the preparation and the analysis of skin samples. Samples from ante mortem wounds, post mortem wounds, and intact skin ("control samples") were taken from corpses at the autopsy. After an optimization of the pre-analytical protocol had been performed in terms of skin homogeneisation and proteic extraction, the concentration of TNF-α was measured in each sample with the MSD ® approach. Then five other cytokines of interest (IL-1β, IL-6, IL-10, IL-12p70 and IFN-γ) were simultaneously quantified with a MSD ® multiplex assay. The optimal pre-analytical conditions consist in a proteic extraction from a 6 mm diameter skin sample, in a PBS buffer with triton 0,05%. Our results show the linearity and the reproductibility of the TNF-α quantification with MSD ® , and an inter- and intra-individual variability of the concentrations of proteins. The MSD ® multiplex assay is likely to detect differential skin concentrations for each cytokine of interest. This preliminary study was used to develop and optimize the pre-analytical and analytical conditions of the MSD ® method using injured and healthy skin samples, for the purpose of looking for and identifying the cytokine, or the set of cytokines, that may be biomarkers of skin wound vitality.
Koskinen, Heli
2007-01-01
An important issue that has received insufficient attention in the use of problem-based learning in the medical curriculum is the mode of assessing the level of difficulty of patient cases. In the present study, the level of difficulty of case-based questions in a veterinary degree final examination in reproduction was evaluated. First, cognitive taxonomies were evaluated to clarify whether qualitative methods such as Bloom's taxonomy, the Structure of the Observed Learning Outcome (SOLO) taxonomy, and the Amsterdam Clinical Challenge Scale (ACCS) differed from each other as evaluation tools for problem-based cases. Using these taxonomies, 30 case-based questions from the final examination in reproduction in the Helsinki veterinary program were initially evaluated to determine which one was best suited to the evaluation of the difficulty of cases. In follow-up, the same cases were also evaluated by an experienced veterinary instructor in reproduction, with the aim of gaining insight into using these approaches to evaluating difficulty. It would appear, from this preliminary assessment, that the SOLO taxonomy may be the most suitable for evaluating the difficulty of patient cases, since the instructor's quality rating resembled more closely the SOLO than the Bloom taxonomy or the ACCS. It is to be emphasized that the purpose of this study was to provide a preliminary evaluation of possible approaches that might be used to assess patient-case difficulty. Resolving all issues will require a greater number of evaluations of all components.
Quilty, Lena C; Taylor, Graeme J; McBride, Carolina; Bagby, R Michael
2017-08-01
Previous studies have found that alexithymia predicts process and outcome of psychodynamic psychotherapy across a range of psychiatric disorders. There is preliminary evidence that alexithymia may exert its effects on outcome through the therapist. Other studies have found that alexithymia does not influence outcome of cognitive-behavioral therapy (CBT). The aim of the current study was to investigate the capacity of alexithymia to predict therapist- and patient-rated therapeutic alliance and response to CBT and interpersonal psychotherapy (IPT) for major depressive disorder. A total of 75 adults with major depressive disorder were randomized to receive weekly sessions of manualized individual CBT or IPT for a period of 16 weeks. Pre-treatment alexithymia exhibited a positive direct effect on depression change, and a negative indirect effect on depression change via patient-rated alliance at week 13. There was no mediating role of therapist-rated alliance. Although these findings are preliminary, they suggest that pre-treatment alexithymia has meaningful links to psychotherapy process and outcome, and that nuanced analyses incorporating intervening variables are necessary to elucidate the nature of these links. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.
Brunetti, L; Santoro, E; De Caro, F; Cavallo, P; Boccia, G; Capunzo, M; Motta, O
2006-06-01
The observance of hand hygiene compliance is important to reduce cross-infection by micro-organisms. The aim of this preliminary study was to evaluate the level of hand hygiene in healthcare workers from different departments, with particular emphasis on transient flora. The study was conducted in three departments (Surgery, Intensive Care Unit, Obstetrics and Gynecology) of a hospital in Campania, southern Italy. Over a six-month period, 50 healthcare workers were randomly tested. Imprints of palms and fingertips were taken monthly during the morning shift. The number of colonies per plate was counted and transient pathogens were identified. Risk factors for hand contamination were determined. Total flora was found in the following CFU means per palm and per five fingertips (95% CI): Obstetrics and Gynecology [palms 130 CFUs (95% CI 85-180); fingertips 125 CFUs (95% CI 92-160)]; ICU [palms 80 CFUs (95% CI 58-99); fingertips 62 CFUs (95% CI 45-82)]; Surgery [palms 75 CFUs (95% CI 41-120); fingertips 70 CFUs (95% CI 52-90)] Transient flora was found on 39% of healthcare workers' hands. The only factor associated with hand contamination by transient flora was the absence of gloving during healthcare procedure (P = 0.02).
NASA Astrophysics Data System (ADS)
Righetti, Raffaella; Garra, Brian S.; Mobbs, Louise M.; Kraemer-Chant, Christina M.; Ophir, Jonathan; Krouskop, Thomas A.
2007-11-01
Lymphedema is a common condition involving an abnormal accumulation of lymphatic fluid in the interstitial space that causes swelling, most often in the arm(s) and leg(s). Lymphedema is a significant lifelong concern that can be congenital or develop following cancer treatment or cancer metastasis. Common methods of evaluation of lymphedema are mostly qualitative making it difficult to reliably assess the severity of the disease, a key factor in choosing the appropriate treatment. In this paper, we investigate the feasibility of using novel elastographic techniques to differentiate between lymphedematous and normal tissues. This study represents the first step of a larger study aimed at investigating the combined use of elastographic and sonographic techniques for the detection and staging of lymphedema. In this preliminary study, poroelastographic images were generated from the leg (8) and arm (4) subcutis of five normal volunteers and seven volunteers having lymphedema, and the results were compared using statistical analyses. The preliminary results reported in this paper suggest that it may be feasible to perform poroelastography in different lymphedematous tissues in vivo and that poroelastography techniques may be of help in differentiating between normal and lymphedematous tissues.
Lardon, Arnaud; Girard, Marie-Pier; Zaïm, Chérine; Lemeunier, Nadège; Descarreaux, Martin; Marchand, Andrée-Anne
2017-01-01
Aim The purpose of this systematic literature review is to assess the benefits of workplace-based occupational therapies and interventions, including acute and preventive medication, on headache intensity and frequency, related disability as well as work-related outcomes. Methods A search of the literature was conducted in PubMed, MEDLINE, Cochrane library, CINAHL and Embase using terms related to headache, workplace and occupational health. The Cochrane Collaboration's risk of bias assessment tool was used on individual studies to assess internal validity and the Grading of Recommendations Assessment, Development, and Evaluation system was applied to studies by clinical outcome and used to rate quality of evidence. Results Fifteen articles were included in the systematic review. None of them were classified as low risk of bias according to the Cochrane Collaboration's tool for assessing risk of bias. This systematic review found preliminary low-quality evidence suggesting that exercise and acupuncture can reduce workers' headache pain intensity, frequency and related disability. Conclusion Although this systematic review provided preliminary low evidence in favour of work-based intervention, studies with more rigorous designs and methodologies are needed to provide further evidence of the effectiveness of workplace-based headache management strategies.
Dean, R E; Kennedy, Paul
2009-05-01
The current study aimed to develop a reliable and valid appraisal scale (The Appraisals of DisAbility: Primary and Secondary Scale; ADAPSS) for adult spinal cord injury (SCI) populations. Items for the ADAPSS were generated using themes and quotes from a qualitative study exploring appraisals made by individuals with SCI. The ADAPSS was administered with 2 additional appraisal measures, a measure of anxiety and depression, a measure of social desirability and demographic information. The study used a cross-sectional questionnaire design with a test-retest component, sampling community-based individuals with SCI. Data analysis was undertaken on 237 completed questionnaires. Factor analysis revealed the ADAPSS to have a 6-factor structure and the following subscales identified: (a) Fearful Despondency, (b) Overwhelming Disbelief, (c) Determined Resolve, (d) Growth and Resilience, (e) Negative Perceptions of Disability, and (f) Personal Agency. Preliminary analyses suggest the ADAPSS demonstrates reasonable reliability and validity and has potential as a therapeutic outcome measure. Future research should focus on the relationship between appraisals identified on the ADAPSS and their relationship to the coping strategies that individuals employ and adjustment to SCI. (PsycINFO Database Record (c) 2009 APA, all rights reserved).
NASA Astrophysics Data System (ADS)
Rahyussalim A., J.; Kurniawati, T.; Aprilya, D.; Anggraini, R.; Ramahdita, Ghiska; Whulanza, Yudan
2017-02-01
Scaffold as a biomaterial must fulfill some requirements to be safely implanted to the human body. Toxicity and biocompatibility test are needed to evaluate scaffold material in mediating cell proliferation and differentiation, secreting extracelullar matrix and carrying biomolecular signals for cell communication. An in vitro study with mesenchymal stem cells consisted of direct contact test and indirect contact test using MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) tetrazolium reduction assay was conducted on 4 scaffolds made of poly-L-lactic acid (PLA), polyvinyl alcohol (PVA), and hydroxyapatite-poly (vinyl alcohol) composite. There were cells-substrate adhesion impairment, morphological changes, cell death and reduction in cell proliferation seen at 2nd and 6th day in most tested scaffold. Cell count result at day-6 showed proliferation inhibition of more than 50% cell death (inhibition value >50) in all tested scaffold. In MTT assay, two scaffolds were proven non-toxic. In conclusion, various scaffold materials showed different toxicity effect. The toxicity and biocompatibility profile in this study is a preliminary data for further research aiming to use those local-made scaffolds to fill human bone defect in various needs.
Methacrylate micro/nano particles prepared by spray drying: a preliminary in vitro/in vivo study.
Muñoz Ortega, Begoña; Sallam, Marwa Ahmed; Marín Boscá, M Teresa
2016-09-01
Delivery systems controlling drug release only in the colon holds great promises since they improve utilization of drug and decrease the dosing times comparison with conventional forms. The aim of the present study was to prepare polymeric microparticles on the basis of Ciprofloxacin via oral route for the treatment of inflammatory bowel disease. Ciprofloxacin was selected because of its extensive coverage for intestinal flora, relatively favorable side-effect profile and preliminary data suggesting its efficacy in the treatment of active Crohn's Disease. Microparticles were prepared using different acrylic compounds, namely Eudragit® RL (PO) and RS (PO) and a mixture of both. Spray-drying was used as a preparation method of Ciprofloxacin/Eudragit® microparticles using a Mini Spray Dryer B-290 (Büchi, Postfach, Switzerland). In vitro dissolution studies were performed to choose the best formulation and selected microparticles were characterized by size and morphology by environmental scanning electron microscopy. Yield and encapsulation efficiency were calculated and in vivo/ex vivo experiments were investigated both of which suggest that selected microparticles can be used for colon targeting of drugs increasing residence time of the drug in the affected area.
McKeon, Ashlee; Terhorst, Lauren; Skidmore, Elizabeth; Ding, Dan; Cooper, Rory; McCue, Michael
2017-01-01
This study aimed to develop a novel tool for measuring behavioural dysregulation in adults with traumatic brain injury (TBI) using objective data sources and real-world application and provide preliminary evidence for its psychometric properties. Fourteen adults with TBI receiving services at a local brain injury rehabilitation programme completed multiple assessments of behaviour and followed by a series of challenging problem-solving tasks while being video recorded. Trained clinicians completed post-hoc behavioural assessments using the behavioural dysregulation ratings scale, and behavioural event data were then extracted for comparison with self-report measures. Subject matter experts in neurorehabilitation were in 100% agreement that preliminarily, the new tool measured the construct of behavioural dysregulation. Construct validity was established through strong convergence with 'like' measures and weak correlation with 'unlike' measures. Substantial inter-rater reliability was established between two trained clinician raters. This study provides preliminary evidence supporting the use of a new precision measurement tool of behaviour in post-acute TBI that has the capability to be deployed naturalistically where deficits truly manifest. Future large-scaled confirmatory psychometric trials are warranted to further establish the utility of this new tool in rehabilitation research.
Zamani, Elham; Kordi, Ramin; Nourian, Ruhollah; Noorian, Negin; Memari, Amir Hossein; Shariati, Mohammad
2014-12-01
Low Back Pain (LBP) is one of the most prevalent causes of disability not only in the general population but also in athletes. Despite a large number of self-reported back specific disability questionnaires, there is no specific, well documented, outcome measure for athletes suffering from back pain. This study aimed to identify the main descriptive themes representing functional disability in athletes due to LBP. We conducted a qualitative study using in-depth interviews to characterize the experiences of athletes with LBP. Twenty athletes with LBP were recruited and the main descriptive elements of their LBP related disability were extracted. Then a preliminary questionnaire using these themes was proposed. The main disability indicators were pain intensity; stretching exercises, strengthening exercises, sport specific skills, back range of motion (ROM), sitting, walking, sleep patterns, self-care, and recreational activities, fear of pain and avoidance behavior, and changes in sexual activity. The findings of this study suggest that apart from non-sports items, some sport related items should be included in the assessment of LBP disability levels in athletes. Our results have also been organized as a preliminary LBP disability questionnaire for athletes.
Tailored Prevention of Inpatient Falls
ZUYEV, LYUBOV; BENOIT, ANGELA N.; CHANG, FRANK Y.; DYKES, PATRICIA C.
2011-01-01
Patient falls and fall-related injuries are serious problems in hospitals. The Fall TIPS application aims to prevent patient falls by translating routine nursing fall risk assessment into a decision support intervention that communicates fall risk status and creates a tailored evidence-based plan of care that is accessible to the care team, patients, and family members. In our design and implementation of the Fall TIPS toolkit, we used the Spiral Software Development Life Cycle model. Three output tools available to be generated from the toolkit are bed poster, plan of care, and patient education handout. A preliminary design of the application was based on initial requirements defined by project leaders and informed by focus groups with end users. Preliminary design partially simulated the paper version of the Morse Fall Scale currently used in hospitals involved in the research study. Strengths and weaknesses of the first prototype were identified by heuristic evaluation. Usability testing was performed at sites where research study is implemented. Suggestions mentioned by end users participating in usability studies were either directly incorporated into the toolkit and output tools, were slightly modified, or will be addressed during training. The next step is implementation of the fall prevention toolkit on the pilot testing units. PMID:20975543
Zamani, Elham; Kordi, Ramin; Nourian, Ruhollah; Noorian, Negin; Memari, Amir Hossein; Shariati, Mohammad
2014-01-01
Background: Low Back Pain (LBP) is one of the most prevalent causes of disability not only in the general population but also in athletes. Despite a large number of self-reported back specific disability questionnaires, there is no specific, well documented, outcome measure for athletes suffering from back pain. Objectives: This study aimed to identify the main descriptive themes representing functional disability in athletes due to LBP. Patients and Methods: We conducted a qualitative study using in-depth interviews to characterize the experiences of athletes with LBP. Twenty athletes with LBP were recruited and the main descriptive elements of their LBP related disability were extracted. Then a preliminary questionnaire using these themes was proposed. Results: The main disability indicators were pain intensity; stretching exercises, strengthening exercises, sport specific skills, back range of motion (ROM), sitting, walking, sleep patterns, self-care, and recreational activities, fear of pain and avoidance behavior, and changes in sexual activity. Conclusions: The findings of this study suggest that apart from non-sports items, some sport related items should be included in the assessment of LBP disability levels in athletes. Our results have also been organized as a preliminary LBP disability questionnaire for athletes. PMID:25741417
Palmiere, Cristian; Tettamanti, Camilla
2018-06-01
Increased infection susceptibility in the diabetic population is a controversial issue in the clinical field. The greater frequency of infections in diabetic patients has been speculated as caused by the hyperglycemic environment that favors immune dysfunction. The aim of this study was to investigate the proportion of positive bacterial cultures in a series of diabetic individuals who underwent forensic investigations and assess the frequency of hyperglycemia at the time of death in these cases as well as the percentage of diabetics with cause of death due to bacterial infection. Forensic autopsy cases characterized by positive bacterial cultures and pre-existing diagnosis of diabetes mellitus were included in the study. Initial findings revealed that 12% (7/58 cases) of positive bacterial cultures concerned individuals with a pre-existing diagnosis of diabetes mellitus. Bacterial infection was considered to be the cause of death in 22% (7/31 cases) of diabetics with positive bacterial cultures. Hyperglycemia could be identified in 1 case only at the time of death. These preliminary results highlight the usefulness of systematically performing postmortem bacteriology in the forensic setting to more precisely characterize infectious risk factors in diabetics.
76 FR 47529 - Port Access Route Study: In the Waters of Montauk Channel and Block Island Sound
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-05
.... ACTION: Notice of availability of Preliminary Study Recommendations with request for comments. SUMMARY: The Coast Guard announces the availability of Preliminary Study Recommendations of a Port Access Route... study area. Preliminary recommendations indicate that marine transportation safety would be enhanced...
Praveena, Sarva Mangala; Chen, Kwan Soo; Ismail, Sharifah Norkhadijah Syed
2013-11-15
This study aims to determine the concentrations of total coliforms and Escherichia coli (E. coli) in beach water, Teluk Kemang beach. This study was also aimed to determine relationship between total coliforms, E. coli and physicochemical parameters. As perceived health symptoms among beach visitors are rarely incorporated in beach water studies, this element was also assessed in this study. A total of eight water sampling points were selected randomly along Teluk Kemang beach. Total coliforms concentrations were found between 20 and 1940 cfu/100ml. E. coli concentrations were between 0 and 90 cfu/100ml. Significant correlations were found between total coliforms and E. coli with pH, temperature and oxidation reduction potential. Skin and eyes symptoms were the highest reported though in small numbers. Microbiological water quality in Teluk Kemang public beach was generally safe for recreational activities except sampling location near with sewage outfall. Copyright © 2013 Elsevier Ltd. All rights reserved.
Narrative Enhancement and Cognitive Therapy (NECT) Effectiveness: A Quasi-Experimental Study
Roe, David; Hasson-Ohayon, Ilanit; Mashiach-Eizenberg, Michal; Derhy, Oren; Lysaker, Paul H.; Yanos, Philip T.
2014-01-01
Objective Accumulated evidence suggests that approximately one third of people with a serious mental illness (SMI) experience elevated self-stigma. Narrative enhancement and cognitive therapy (NECT) is a structured group-based intervention aimed to reduce self-stigma. The current study aims to examine the effectiveness of NECT. A quasi-experimental design. Design Baseline and follow-up data were collected and outcomes were compared between 63 persons with SMI who participated in NECT and 56 persons who received treatment as usual. Results The NECT treatment group showed significant (p < .05) reductions in self-stigma and increases in self-esteem, quality of life, and Hope-Agency scores between pre- and posttreatment assessments, compared with the control group. Conclusions The current results provide preliminary support for the use of NECT as an effective treatment to reduce self-stigma and its implications for treatment and practice are discussed. PMID:24114797
The Effect of Alkaline Activator Ratio on the Compressive Strength of Fly Ash-Based Geopolymer Paste
NASA Astrophysics Data System (ADS)
Lăzărescu, A. V.; Szilagyi, H.; Baeră, C.; Ioani, A.
2017-06-01
Alkaline activation of fly ash is a particular procedure in which ash resulting from a power plant combined with a specific alkaline activator creates a solid material when dried at a certain temperature. In order to obtain desirable compressive strengths, the mix design of fly ash based geopolymer pastes should be explored comprehensively. To determine the preliminary compressive strength for fly ash based geopolymer paste using Romanian material source, various ratios of Na2SiO3 solution/ NaOH solution were produced, keeping the fly ash/alkaline activator ratio constant. All the mixes were then cured at 70 °C for 24 hours and tested at 2 and 7 days, respectively. The aim of this paper is to present the preliminary compressive strength results for producing fly ash based geopolymer paste using Romanian material sources, the effect of alkaline activators ratio on the compressive strength and studying the directions for future research.
Sensorized toys for measuring manipulation capabilities of infants at home.
Passetti, Giovanni; Cecchi, Francesca; Baldoli, Ilaria; Sgandurra, Giuseppina; Beani, Elena; Cioni, Giovanni; Laschi, Cecilia; Dario, Paolo
2015-01-01
Preterm infants, i.e. babies born after a gestation period shorter than 37 weeks, spend less time exploring objects. The quantitative measurement of grasping actions and forces in infants can give insights on their typical or atypical motor development. The aim of this work was to test a new tool, a kit of sensorized toys, to longitudinally measure, monitor and promote preterm infants manipulation capabilities with a purposive training in an ecological environment. This study presents preliminary analysis of grasping activity. Three preterm infants performed 4 weeks of daily training at home. Sensorized toys with embedded pressure sensors were used as part of the training to allow quantitative analysis of grasping (pressure and acceleration applied to toys while playing). Each toy was placed on the midline, while the infant was in supine position. Preliminary data show differences in the grasping parameters in relation to infants age and the performed daily training. Ongoing clinical trial will allow a full validation of this new tool for promoting object exploration in preterm infants.
Investigation of the reaction d + d → {sup 2}He + {sup 2}n at the deuteron energy of 15 MeV
DOE Office of Scientific and Technical Information (OSTI.GOV)
Konobeevski, E. S., E-mail: konobeev@inr.ru; Zuyev, S. V.; Kasparov, A. A.
An experimental setup for studying the reaction d + d → {sup 2}He + {sup 2}n is described, and the first preliminary results of measurements at a deuteron energy of 15 MeV are presented. The experiment was aimed at determining the energies of quasibound singlet states of two-nucleon systems (nn and pp), these energies being important features of nucleon–nucleon (NN) interaction. The measurements in question were performed at a deuteron beamfrom the U-120 cyclotron of the Skobeltsyn Institute ofNuclear Physics (Moscow State University). Two protons and one of the neutrons fromthe breakup of the dineutron system were detected in themore » experiment. A simulation of the reaction in question and preliminary experimental results reveal the possibility of determining the energy of quasibound singlet states on the basis of the form of the energy spectra of particles originating from their breakup.« less
Stochastic Methods for Aircraft Design
NASA Technical Reports Server (NTRS)
Pelz, Richard B.; Ogot, Madara
1998-01-01
The global stochastic optimization method, simulated annealing (SA), was adapted and applied to various problems in aircraft design. The research was aimed at overcoming the problem of finding an optimal design in a space with multiple minima and roughness ubiquitous to numerically generated nonlinear objective functions. SA was modified to reduce the number of objective function evaluations for an optimal design, historically the main criticism of stochastic methods. SA was applied to many CFD/MDO problems including: low sonic-boom bodies, minimum drag on supersonic fore-bodies, minimum drag on supersonic aeroelastic fore-bodies, minimum drag on HSCT aeroelastic wings, FLOPS preliminary design code, another preliminary aircraft design study with vortex lattice aerodynamics, HSR complete aircraft aerodynamics. In every case, SA provided a simple, robust and reliable optimization method which found optimal designs in order 100 objective function evaluations. Perhaps most importantly, from this academic/industrial project, technology has been successfully transferred; this method is the method of choice for optimization problems at Northrop Grumman.
New program for identification of child maltreatment in emergency department: preliminary data.
Milani, Gregorio P; Vianello, Federica A; Cantoni, Barbara; Agostoni, Carlo; Fossali, Emilio F
2016-07-13
Early detection of child maltreatment in pediatric emergency department is one of the most important challenges for the Italian and European medical care system. Several interventions have been proposed, but results are often unquantifiable or inadequate to face this problem. We promoted an educational program and built up an interdisciplinary team to improve the identification and management of maltreated children. Aim of this study is to report preliminary results of these interventions. Meetings structured with lecture-based teaching and case-based lessons were focused on identification and management of maltreatment cases. An interdisciplinary team with forensic physicians, dermatologists, orthopedics, radiologists, gynecologists, oculists, psychologists and psychiatrics, was created to manage children with suspected diagnosis of maltreatment. We analysed the characteristics of subjects diagnosed after these interventions and their number was compared with the one in the two previous years. An increased rate of diagnoses of 16.9 % was found. Results of the reported program are encouraging, but many efforts are still mandatory to improve the child maltreatment identification in emergency departments.
Porter, Laura S; Keefe, Francis J; Baucom, Donald H; Olsen, Maren; Zafar, S Yousuf; Uronis, Hope
2017-07-01
This study aims to test the feasibility and preliminary efficacy of a couple-based communication intervention for advanced GI cancer delivered via videoconference. Thirty-two couples were randomly assigned to either couples communication skills training (CCST) or an education comparison intervention, both delivered via videoconference. Participation was limited to couples who reported communication difficulties at screening. Patients and partners completed measures of relationship functioning and individual functioning at baseline and post-intervention. Eighty-eight percent of randomized dyads completed all six sessions and reported high levels of satisfaction with the intervention. Between-group effect sizes suggested that the CCST intervention led to improvements in relationship satisfaction for patients and partners and to improvements in intimacy and communication for patients. A couples-based communication intervention delivered via videoconference is feasible and acceptable in the context of advanced cancer. Preliminary findings suggest that the intervention shows promise in contributing to enhanced relationship functioning. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.
Microscopic Examination of Cold Spray Cermet Sn+In2O3 Coatings for Sputtering Target Materials
Baszczuk, A.; Rutkowska-Gorczyca, M.; Jasiorski, M.; Małachowska, A.; Posadowski, W.; Znamirowski, Z.
2017-01-01
Low-pressure cold spraying is a newly developed technology with high application potential. The aim of this study was to investigate potential application of this technique for producing a new type of transparent conductive oxide films target. Cold spraying technique allows the manufacture of target directly on the backing plate; therefore the proposed sputtering target has a form of Sn+In2O3 coating sprayed onto copper substrate. The microstructure and properties of the feedstock powder prepared using three various methods as well as the deposited ones by low-pressure cold spraying coatings were evaluated, compared, and analysed. Produced cermet Sn+In2O3 targets were employed in first magnetron sputtering process to deposit preliminary, thin, transparent conducting oxide films onto the glass substrates. The resistivity of obtained preliminary films was measured and allows believing that fabrication of TCO (transparent conducting oxide) films using targets produced by cold spraying is possible in the future, after optimization of the deposition conditions. PMID:29109810
Microscopic Examination of Cold Spray Cermet Sn+In2O3 Coatings for Sputtering Target Materials.
Winnicki, M; Baszczuk, A; Rutkowska-Gorczyca, M; Jasiorski, M; Małachowska, A; Posadowski, W; Znamirowski, Z; Ambroziak, A
2017-01-01
Low-pressure cold spraying is a newly developed technology with high application potential. The aim of this study was to investigate potential application of this technique for producing a new type of transparent conductive oxide films target. Cold spraying technique allows the manufacture of target directly on the backing plate; therefore the proposed sputtering target has a form of Sn+In 2 O 3 coating sprayed onto copper substrate. The microstructure and properties of the feedstock powder prepared using three various methods as well as the deposited ones by low-pressure cold spraying coatings were evaluated, compared, and analysed. Produced cermet Sn+In 2 O 3 targets were employed in first magnetron sputtering process to deposit preliminary, thin, transparent conducting oxide films onto the glass substrates. The resistivity of obtained preliminary films was measured and allows believing that fabrication of TCO (transparent conducting oxide) films using targets produced by cold spraying is possible in the future, after optimization of the deposition conditions.
Minimally invasive periodontal therapy
Dannan, Aous
2011-01-01
Minimally invasive dentistry is a concept that preserves dentition and supporting structures. However, minimally invasive procedures in periodontal treatment are supposed to be limited within periodontal surgery, the aim of which is to represent alternative approaches developed to allow less extensive manipulation of surrounding tissues than conventional procedures, while accomplishing the same objectives. In this review, the concept of minimally invasive periodontal surgery (MIPS) is firstly explained. An electronic search for all studies regarding efficacy and effectiveness of MIPS between 2001 and 2009 was conducted. For this purpose, suitable key words from Medical Subject Headings on PubMed were used to extract the required studies. All studies are demonstrated and important results are concluded. Preliminary data from case cohorts and from many studies reveal that the microsurgical access flap, in terms of MIPS, has a high potential to seal the healing wound from the contaminated oral environment by achieving and maintaining primary closure. Soft tissues are mostly preserved and minimal gingival recession is observed, an important feature to meet the demands of the patient and the clinician in the esthetic zone. However, although the potential efficacy of MIPS in the treatment of deep intrabony defects has been proved, larger studies are required to confirm and extend the reported positive preliminary outcomes. PMID:22368356
Shamsi, Shokoofeh; Loukopoulos, Panayiotis; McSpadden, Kate; Baker, Sara; Jenkins, David
2018-05-23
Tongue worms utilise herbivorous mammals as intermediate hosts and reside in the nasopharynx of carnivores as their definitive hosts. A recent study in south eastern Australia showed an unexpectedly high infection (67%) of wild dogs with these parasites. The present study aimed at determining the pathogenicity of the parasite in both definitive (dog) and intermediate (cattle) hosts by histopathology. The definitive host showed multifocal haemorrhage of the interstitium of the nasal mucosa, multifocal mucosal erosion, congestion and haemorrhage, with haemosiderin laden macrophages present in those foci and distortion and destruction of the nasal mucosa. Histopathologic examination of lymph nodes from an infected cow showed diffuse eosinophilic granulomatous necrotising lymphadenitis and perinodal panniculitis with intralesional parasitic remnants and comparatively large numbers of eosinophils. A large, ~300-500 μm diameter, area of necrosis was also observed in one lymph node. This is the first time a study has been undertaken in Australia to determine the pathogenicity of tongue worms in both their definitive and intermediate hosts. This is a preliminary study and to properly estimate the health impact of infection with this pathogenic parasites on Australian production and companion animals more studies are necessary. Copyright © 2018 Elsevier B.V. All rights reserved.
In vivo soft tissue differentiation by diffuse reflectance spectroscopy: preliminary results
NASA Astrophysics Data System (ADS)
Zam, Azhar; Stelzle, Florian; Tangermann-Gerk, Katja; Adler, Werner; Nkenke, Emeka; Neukam, Friedrich Wilhelm; Schmidt, Michael; Douplik, Alexandre
Remote laser surgery does not provide haptic feedback to operate layer by layer and preserve vulnerable anatomical structures like nerve tissue or blood vessels. The aim of this study is identification of soft tissue in vivo by diffuse reflectance spectroscopy to set the base for a feedback control system to enhance nerve preservation in oral and maxillofacial laser surgery. Various soft tissues can be identified by diffuse reflectance spectroscopy in vivo. The results may set the base for a feedback system to prevent nerve damage during oral and maxillofacial laser surgery.
[Preliminary approach to the mental component in dermatologic patients].
Di Prima, T M; De Pasquale, R; Gilotta, S M; Cravotta, A
1989-04-01
The aim of this study was to approach on a psychical point of view 27 patients suffering from chronic idiopathic urticaria (14), pruritus sine materia (6), alopecia areata (3), pathomimia (4), in order to examine the possibility that psychic disorders could act as triggering or aggravating the dermatological affection. Psychical assessment was evaluated by colloquy and by the administration of some psychodiagnostic tests: EPI, MMPI, Zung. The role of psychogenic factors in skin diseases is emphasized and the results obtained from the use of antidepressant and minor tranquilizer drugs are discussed.
Systematic Study of Three-Nucleon System Dynamics in Deuteron-Proton Breakup Reaction
NASA Astrophysics Data System (ADS)
Kozela, A.; Ciepał, I.; Garbacz, M.; Jamróz, B.; Kłos, B.; Kistryn, St.; Khatri, G.; Kuboś, J.; Kulessa, P.; Liptak, A.; Parol, W.; Rusnok, A.; Sȩkowski, P.; Skwira-Chalot, I.; Stephan, E.; Wilczek, A.; Włoch, B.; Zejma, J.
2017-03-01
We report on preliminary results of the first measurement of elastic scattering of protons from deuterons and proton induced deuteron breakup at proton beam energy of 108 MeV conducted at new Cyclotron Center Bronowice IFJ PAN in Kraków. The experiment is aimed at precise determination of the differential cross section for extensive set of kinematical configurations in a wide range of angular acceptance. In the first data taking run the average statistical per-point accuracy of about 5% has been reached.
NASA Technical Reports Server (NTRS)
1979-01-01
An environmentally oriented microwave technology exploratory research program aimed at reducing the uncertainty associated with microwave power system critical technical issues is described. Topics discussed include: (1) Solar Power Satellite System (SPS) development plan elements; (2) critical technology issues related to the SPS preliminary reference configuration; (3) pilot plant to demonstrate commercial viability of the SPS system; and (4) research areas required to demonstrate feasibility of the SPS system. Progress in the development of advanced GaAs solar cells is reported along with a power distribution subsystem.
Geothermal space/water heating for City of Mammoth Lakes, California. Draft final report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sims, A.V.; Racine, W.C.
1977-09-01
The results of a study to determine the technical, economic and environmental feasibility of geothermal district heating for Mammoth Lakes Village, California are presented. The geothermal district heating system selected is technically feasible and uses existing technology in its design and operation. During a preliminary environmental assessment, no potential adverse environmental impacts could be identified of sufficient consequence to preclude the construction and operation of the proposed district heating system. A follow-on program aimed at implementing district heating in Mammoth is outlined.
STUDY OP THE 12C(α, γ)16O REACTION BY BREAKUP OF A 16O -BEAM AT 100 MeV/A
NASA Astrophysics Data System (ADS)
Tatischeff, V.; Kiener, J.; Aguer, P.; Angulo-Perez, C.; Bogaert, G.; Coc, A.; Disdier, D.; Ichihara, T.; Kraus, L.; Lefebvre, A.; Linck, I.; Mittig, W.; Motobayashi, T.; Oliveira, F.; Roussel-Chomaz, P.; Stephan, C.; Thibaud, J. P.
We present some preliminary calculations on cross sections for the breakup of 16O around 100 MeV/A with emphasis on the effect of nuclear breakup on the angular distributions. Underlying the results of these calculations, the possibilities and problems of extracting the astrophysical S-factor for the 12C(α, γ)16O reaction at very low energies are discussed. Some considerations on the experimental conditions for a 16O breakup experiment aiming at this astrophysical information, are given.
Effect of training level and blood flow restriction on thermal parameters: Preliminary study
NASA Astrophysics Data System (ADS)
Sampaio, Lucas; Bezerra, Ewertton; Paladino, Kayo; dos Santos, João Otacílio Libardoni; Priego Quesada, Jose I.; Rossato, Mateus
2016-11-01
Training with blood flow restriction could lead to an effect on skin temperature. Additionally, this effect could be higher in people with lower physical fitness level due to their lower capacity of heat loss. The aim of this preliminary study was therefore to evaluate the effects of training experience on the acute and chronic thermal skin responses after performing exercise with and without blood flow restriction. The study included ten men, of these, five were trained. All subjects performed tests and re-tests for maximum strength (1 repetition maximum) through unilateral leg extensions (right thigh at 45 ± 6.7 kg and left thigh at 45.5 ± 8.1 kg, p > 0.05). The protocol consisted of four sets to concentric failure, with one-minute rest intervals between sets at an intensity corresponding to 40% of 1 RM. There were 7-day intervals between experimental sessions (150 mmHg versus unrestricted flow restriction). The thermal images were made before the protocol (pre), immediately after the end of the series (post), and 24 h afterward (post 24 h). When comparing temperature variation (Δ exercise and Δ 24 h) between groups, it was observed that the trained participants showed a greater drop in temperature 24 h after exercise with 150 mmHg restriction (confidence interval: 95% of Δ 24 h [-0.2 to -0.9 °C]) compared to untrained subjects (p = 0.006 and ES > 1.5, confidence interval: 95% Δ 24 h [-0.1 to 0.6 °C].) In conclusion, this preliminary study showed that training experience interferes with the chronic cutaneous thermal temperature of the anterior thigh when strength training associated with blood flow restriction 150 mmHg was performed.
Dimitroulis, George; Austin, Stephen; Sin Lee, Peter Vee; Ackland, David
2018-05-16
The aim of this study is to present the preliminary clinical data on the OMX Temporomandibular Joint (TMJ) Prosthetic total joint replacement system. A prospective, cohort, clinical study was undertaken of consecutive adult patients with Category 5 end-stage joint disease who were implanted with the OMX TMJ prosthesis between May 2015 and April 2017. A total of 50 devices were implanted in 38 patients, with 12 patients receiving bilateral prosthetic joints. There were 31 females and 7 males in this cohort, who ranged in age from 20 to 66 years, with a mean of 43.8 years (±14.0 years). Ten of the 50 prosthetic joints (20%) were fully customized, while the remaining were patient matched using virtual planning software. Based on a mean follow-up period of 15.3 months (range 12-24 months) following the TMJ total joint replacement, preliminary results suggest the OMX TMJ prosthesis has made a positive impact on clinical outcomes, with a mean 74.4% reduction in joint pain levels and significant improvements (p < 0.05) in jaw function as measured by the visual analogue scales for mouth opening (30.8%), diet (77.1%), and function (59.2%). No device failures were reported during the study period. This study suggests that the print-on-demand OMX TMJ prosthesis, designed for rapid delivery of both patient-matched and fully customize devices, represents a safe, reliable and versatile implantable joint replacement system for the treatment of category 5 end-stage TMJ disease. Copyright © 2018 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
Preliminary study on radio-chemo-induced oral mucositis and low level laser therapy
NASA Astrophysics Data System (ADS)
Merigo, Elisabetta; Fontana, Matteo; Fornaini, Carlo; Clini, Fabio; Cella, Luigi; Vescovi, Paolo; Oppici, Aldo
2012-09-01
Background: Oral mucositis remains one of the most common and troubling side effects of antineoplastic radiation and drug therapy: its incidence in onco-hematological radio-chemotreated patients is variable between 50 and 100% and its impact on this populations is directly linked with the experience of intense pain causing reduction and modification of therapy regimens, decreased survival rates and increased cost of care. Purpose: Aim of this study is the preliminary evaluation of a Low Level Laser therapy (LLLT) protocol on healing process of oral mucositis and on pain and quality of life of patients experiencing this dramatic side-effect. Materials and methods: Patients were evaluated and treated at the Unita` Operativa Semplice Dipartimentale di Odontostomatologia e Chirurgia Maxillo-Facciale of the Hospital of Piacenza were they were treated for primary disease with protocols of chemotherapy and/or radiotherapy. LLLT protocol was performed with a diode laser (808 nm -XD Smile - Fotona -Slovenia) on a two weeks-6 treatments schedule with power of 0.5 W and application of 30 seconds. Mucositis grading was scored on the basis of WHO classification by two blind operators at each treatment and at 1 and 2 weeks after treatment. Pain and capability of deglutition were described by patients by means questionnaires based on Visual Analogue Scale, Numerical Rating Scale and Quality of Life. Results: A relevant improvement of healing of oral mucositis, in terms of reduction of grading score, and of pain, swallowing discomfort and quality of life was recorded. Discussion and conclusion: Results of this preliminary study are encouraging for the realization of larger studies focused on the application of LLLT protocols in management of radio-chemotreated patients with oral mucositis.
Initiating Sustainable Operations at Marshall Space Flight Center
NASA Technical Reports Server (NTRS)
Adams, Daniel E.; Orrell, Josh
2003-01-01
Marshall Space Flight Center conducted a preliminary sustainability assessment to identify sustainable projects for potential implementation at its facility in Huntsville, Alabama. This presentation will discuss the results of that assessment, highlighting current and future initiatives aimed at integrating sustainability into daily operations.
SU-E-J-128: Two-Stage Atlas Selection in Multi-Atlas-Based Image Segmentation
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhao, T; Ruan, D
2015-06-15
Purpose: In the new era of big data, multi-atlas-based image segmentation is challenged by heterogeneous atlas quality and high computation burden from extensive atlas collection, demanding efficient identification of the most relevant atlases. This study aims to develop a two-stage atlas selection scheme to achieve computational economy with performance guarantee. Methods: We develop a low-cost fusion set selection scheme by introducing a preliminary selection to trim full atlas collection into an augmented subset, alleviating the need for extensive full-fledged registrations. More specifically, fusion set selection is performed in two successive steps: preliminary selection and refinement. An augmented subset is firstmore » roughly selected from the whole atlas collection with a simple registration scheme and the corresponding preliminary relevance metric; the augmented subset is further refined into the desired fusion set size, using full-fledged registration and the associated relevance metric. The main novelty of this work is the introduction of an inference model to relate the preliminary and refined relevance metrics, based on which the augmented subset size is rigorously derived to ensure the desired atlases survive the preliminary selection with high probability. Results: The performance and complexity of the proposed two-stage atlas selection method were assessed using a collection of 30 prostate MR images. It achieved comparable segmentation accuracy as the conventional one-stage method with full-fledged registration, but significantly reduced computation time to 1/3 (from 30.82 to 11.04 min per segmentation). Compared with alternative one-stage cost-saving approach, the proposed scheme yielded superior performance with mean and medium DSC of (0.83, 0.85) compared to (0.74, 0.78). Conclusion: This work has developed a model-guided two-stage atlas selection scheme to achieve significant cost reduction while guaranteeing high segmentation accuracy. The benefit in both complexity and performance is expected to be most pronounced with large-scale heterogeneous data.« less
Molindone and haloperidol in tardive dyskinesia.
Glazer, W M; Hafez, H M; Benarroche, C L
1985-08-01
Preliminary results are described from a study of 11 outpatients manifesting exacerbated tardive dyskinesia after tapering and withdrawal of neuroleptic medications. Patients were randomly assigned to molindone or haloperidol under double-blind placebo-controlled conditions to compare the masking effects of the two drugs. Haloperidol treatment masked withdrawal-exacerbated tardive dyskinesia more than molindone did; this difference (measured by percent change in AIMS scores) was significant (p = .04) when the dose was 200% but not 100% of the prestudy neuroleptic dose. Despite several limitations to the study, the results suggest that molindone may have less dyskinetogenic potential than haloperidol. Further research in the area of site-specificity of molindone is indicated.
Hultberg, Eva-Lisa; Lönnroth, Knut; Allebeck, Peter
2002-01-01
In this paper, we present an ongoing research project aimed to determine the impact of co-financing on collaboration around patients with musculoskeletal disorders. A trial legislation that allows the social insurance, social services and health care services to unite in co-financing under joint political steering has been tested in different areas in Sweden. In a series of studies, we compare collaboration processes and health outcome for patients with musculoskeletal disorders between health centres with co-financing projects and control health centres without co-financing projects. In this paper the studies are described and some preliminary results are discussed.
Neurocognitive findings in compulsive sexual behavior: a preliminary study.
Derbyshire, Katherine L; Grant, Jon E
2015-06-01
BACKGROUND AND AIMS :Compulsive sexual behavior (CSB) is a common behavior affecting 3-6% of the population, characterized by repetitive and intrusive sexual urges or behaviors that typically cause negative social and emotional consequences. For this small pilot study on neurological data, we compared 13 individuals with CSB and gender- matched healthy controls on diagnostic assessments and computerized neurocognitive testing. No significant differences were found between the groups. These data contradict a common hypothesis that CSB is cognitively different from those without psychiatric comorbidities as well as previous research on impulse control disorders and alcohol dependence. Further research is needed to better understand and classify CSB based on these findings.
Atmosphere behavior in gas-closed mouse-algal systems - An experimental and modelling study
NASA Technical Reports Server (NTRS)
Averner, M. M.; Moore, B., III; Bartholomew, I.; Wharton, R.
1984-01-01
A NASA-sponsored research program initiated using mathematical modelling and laboratory experimentation aimed at examining the gas-exchange characteristics of artificial animal/plant systems closed to the ambient atmosphere is studied. The development of control techniques and management strategies for maintaining the atmospheric levels of carbon dioxide and oxygen at physiological levels is considered. A mathematical model simulating the behavior of a gas-closed mouse-algal system under varying environmental conditions is described. To verify and validate the model simulations, an analytical system with which algal growth and gas exchange characteristics can be manipulated and measured is designed, fabricated, and tested. The preliminary results are presented.
Digestibility of pasta made with three wheat types: a preliminary study.
Simonato, Barbara; Curioni, Andrea; Pasini, Gabriella
2015-05-01
The aim of this study was to assess the digestibility of the protein and starch in pasta made with different cereals, i.e. Triticum durum, Triticum polonicum and Triticum dicoccum, and to measure the glycemic index (GI) of the different types of pasta. The digestibility of the starch in T.polonicum pasta differed significantly from the others. It seemed to be less digested than dicoccum and durum wheat pasta. T.polonicum pasta also had a lower glycemic index, while there were no significant differences in the protein digestibility of the three types of pasta. Copyright © 2014 Elsevier Ltd. All rights reserved.
A Preliminary Data Model for Orbital Flight Dynamics in Shuttle Mission Control
NASA Technical Reports Server (NTRS)
ONeill, John; Shalin, Valerie L.
2000-01-01
The Orbital Flight Dynamics group in Shuttle Mission Control is investigating new user interfaces in a project called RIOTS [RIOTS 2000]. Traditionally, the individual functions of hardware and software guide the design of displays, which results in an aggregated, if not integrated interface. The human work system has then been designed and trained to navigate, operate and integrate the processors and displays. The aim of RIOTS is to reduce the cognitive demands of the flight controllers by redesigning the user interface to support the work of the flight controller. This document supports the RIOTS project by defining a preliminary data model for Orbital Flight Dynamics. Section 2 defines an information-centric perspective. An information-centric approach aims to reduce the cognitive workload of the flight controllers by reducing the need for manual integration of information across processors and displays. Section 3 describes the Orbital Flight Dynamics domain. Section 4 defines the preliminary data model for Orbital Flight Dynamics. Section 5 examines the implications of mapping the data model to Orbital Flight Dynamics current information systems. Two recurring patterns are identified in the Orbital Flight Dynamics work the iteration/rework cycle and the decision-making/information integration/mirroring role relationship. Section 6 identifies new requirements on Orbital Flight Dynamics work and makes recommendations based on changing the information environment, changing the implementation of the data model, and changing the two recurring patterns.
NASA Astrophysics Data System (ADS)
Gaudio, P.; Malizia, A.; Gelfusa, M.; Martinelli, E.; Di Natale, C.; Poggi, L. A.; Bellecci, C.
2017-01-01
Nowadays Toxic Industrial Components (TICs) and Toxic Industrial Materials (TIMs) are one of the most dangerous and diffuse vehicle of contamination in urban and industrial areas. The academic world together with the industrial and military one are working on innovative solutions to monitor the diffusion in atmosphere of such pollutants. In this phase the most common commercial sensors are based on “point detection” technology but it is clear that such instruments cannot satisfy the needs of the smart cities. The new challenge is developing stand-off systems to continuously monitor the atmosphere. Quantum Electronics and Plasma Physics (QEP) research group has a long experience in laser system development and has built two demonstrators based on DIAL (Differential Absorption of Light) technology could be able to identify chemical agents in atmosphere. In this work the authors will present one of those DIAL system, the miniaturized one, together with the preliminary results of an experimental campaign conducted on TICs and TIMs simulants in cell with aim of use the absorption database for the further atmospheric an analysis using the same DIAL system. The experimental results are analysed with standard multivariate data analysis technique as Principal Component Analysis (PCA) to develop a classification model aimed at identifying organic chemical compound in atmosphere. The preliminary results of absorption coefficients of some chemical compound are shown together pre PCA analysis.
Lee, Jong-Sun; You, Sungeun; Choi, Yun-Kyeung; Youn, Hyae-Young; Shin, Hye Sook
2017-01-01
The present study aimed to examine the training effects of a didactic and simulation-based psychological first aid (PFA) program. Based on the competency-based model, the study sought to examine whether the PFA training would enhance knowledge, skills, and attitudes. Study 1 examined the training effects of the PFA program in a sample of undergraduate and graduate students in psychology. Study 2 was conducted with school counselors. In both studies, all participants completed a one-day PFA workshop with a 3-hour didactic lecture and a 3-hour simulation-based practice. Assessments were conducted prior to the didactic lecture and upon completion of the simulation-based practice. In study 1, an examination of pre- and posttest comparisons indicated that the training significantly improved students' PFA knowledge and perceived competence in PFA skill. In study 2, the same PFA training significantly improved school counselors' PFA knowledge, perceived competence in PFA skill, perceived preparedness and confidence to provide psychological assistance for future disasters, but their perceived willingness to participate in psychological assistance did not significantly change after the training. This study provides preliminary evidence supporting the effectiveness of the PFA training program using a combined method of didactic and simulation-based practice for disaster mental health providers in Korea.
Lee, Jong-Sun; Choi, Yun-Kyeung; Youn, Hyae-young; Shin, Hye Sook
2017-01-01
The present study aimed to examine the training effects of a didactic and simulation-based psychological first aid (PFA) program. Based on the competency-based model, the study sought to examine whether the PFA training would enhance knowledge, skills, and attitudes. Study 1 examined the training effects of the PFA program in a sample of undergraduate and graduate students in psychology. Study 2 was conducted with school counselors. In both studies, all participants completed a one-day PFA workshop with a 3-hour didactic lecture and a 3-hour simulation-based practice. Assessments were conducted prior to the didactic lecture and upon completion of the simulation-based practice. In study 1, an examination of pre- and posttest comparisons indicated that the training significantly improved students’ PFA knowledge and perceived competence in PFA skill. In study 2, the same PFA training significantly improved school counselors’ PFA knowledge, perceived competence in PFA skill, perceived preparedness and confidence to provide psychological assistance for future disasters, but their perceived willingness to participate in psychological assistance did not significantly change after the training. This study provides preliminary evidence supporting the effectiveness of the PFA training program using a combined method of didactic and simulation-based practice for disaster mental health providers in Korea. PMID:28715481
Addition of fraction in swimming context
NASA Astrophysics Data System (ADS)
Putri, R. I. I.; Gunawan, M. S.; Zulkardi
2017-12-01
This study aimed to produce learning trajectory that can help students in learning fractions by using swimming context. The study involved 37 fourth grade students with different capabilities in Elementary School IBA, South Sumatra, Indonesia. This study used an instructional theory called Indonesian version of Realistic Mathematics Education (PMRI). This research used design research method with three stages: preliminary design, the design experiment, and retrospective analysis. Several techniques used for collecting data including a video recording of students interaction in the group discussion, students’ work, and interviewing the students. To conclude, the swimming context could stimulate students’ informal knowledge about the meaning of fractions in which it can be used in the additional learning either the same denominator or different denominator.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chan, Wanyu R.; Sidheswaran, Meera; sullivan, Douglas
The HZEB research program aims to generate information needed to develop new science-based commercial building ventilation rate (VR) standards that balance the dual objectives of increasing energy efficiency and maintaining acceptable indoor air quality. This interim report describes the preliminary results from one HZEB field study on retail stores. The primary purpose of this study is to estimate the whole-building source strengths of contaminant of concerns (COCs). This information is needed to determine the VRs necessary to maintain indoor concentrations of COCs below applicable health guidelines.The goal of this study is to identify contaminants in retail stores that should bemore » controlled via ventilation, and to determine the minimum VRs that would satisfy the occupant health and odor criteria.« less
Rasmus, Stacy; Allen, James; Connor, William; Freeman, William; Skewes, Monica
2016-01-01
This paper presents findings from the Native Transformations Project, an exploratory community-based participatory research study that aims to identify sources of strength and protection against substance use disorder in three tribal communities in the coastal Pacific Northwest. Preliminary results from the study describe the specific settings, acts, and behaviors that build strengths and provide protection at the family, community, individual, and spiritual levels within coastal Pacific Northwest local tribal cultures. Findings from this study give voice to stated community preferences for grassroots Native intervention programs based in local cultural knowledge, worldviews, values, and theories of change, that operate at the local level on their own terms.
Study of Light Scattering in the Human Eye
NASA Astrophysics Data System (ADS)
Perez, I. Kelly; Bruce, N. C.; Valdos, L. R. Berriel
2008-04-01
In this paper we present a numerical model of the human eye to be used in studies of the scattering of light in different components of the eye's optical system. Different parts of the eye are susceptible to produce scattering for different reasons; age, illness or injury. For example, cataracts can appear in the human lens or injuries or fungi can appear on the cornea. The aim of the study is to relate the backscattered light, which is what doctors measure or detect, to the forward scattered light, which is what affects the patient's vision. We present the model to be used, the raytrace procedure and some preliminary results for the image on the retina without scattering.
[Aggression and mobbing among correctional officers].
Merecz-Kot, Dorota; Cebrzyńska, Joanna
2008-01-01
The paper addresses the issue of violence among correctional officers. The aim of the study was to assess the frequency of exposure to violence in this professional group. The study comprised the sample of 222 correctional officers who voluntary and anonymously fulfilled the MDM questionnaire. The MDM Questionnaire allows for assessing exposure to aggression and mobbing at work. Preliminary assessment of exposure to single aggressive acts and mobbing shows a quite alarming tendency--around one third of subjects under the study experienced repetitive aggressive acts from coworkers and/or superiors. The problem of organizational aggression in correctional institutions should be recognized in details to develop effective preventive measures against violent behaviors occurring at work.
Rasmus, Stacy; Allen, James; Connor, William; Freeman, William; Skewes, Monica
2016-01-01
This paper presents findings from the Native Transformations Project, an exploratory community-based participatory research study that aims to identify sources of strength and protection against substance use disorder in three tribal communities in the coastal Pacific Northwest. Preliminary results from the study describe the specific settings, acts, and behaviors that build strengths and provide protection at the family, community, individual, and spiritual levels within coastal Pacific Northwest local tribal cultures. Findings from this study give voice to stated community preferences for grassroots Native intervention programs based in local cultural knowledge, worldviews, values, and theories of change, that operate at the local level on their own terms. PMID:27383091
DOT National Transportation Integrated Search
1998-04-01
A methodology is presented for the prediction of delamination growth in laminated structures. The methodology is aimed at overcoming computational difficulties in the determination of energy release rate and mode mix. It also addresses the issue that...
Nogueira-Barbosa, Marcello H.; Gregio-Junior, Everaldo; Lorenzato, Mario Muller
2015-01-01
Objective The present study was aimed at investigating bone involvement secondary to rotator cuff calcific tendonitis at ultrasonography. Materials and Methods Retrospective study of a case series. The authors reviewed shoulder ultrasonography reports of 141 patients diagnosed with rotator cuff calcific tendonitis, collected from the computer-based data records of their institution over a four-year period. Imaging findings were retrospectively and consensually analyzed by two experienced musculoskeletal radiologists looking for bone involvement associated with calcific tendonitis. Only the cases confirmed by computed tomography were considered for descriptive analysis. Results Sonographic findings of calcific tendinopathy with bone involvement were observed in 7/141 (~ 5%) patients (mean age, 50.9 years; age range, 42-58 years; 42% female). Cortical bone erosion adjacent to tendon calcification was the most common finding, observed in 7/7 cases. Signs of intraosseous migration were found in 3/7 cases, and subcortical cysts in 2/7 cases. The findings were confirmed by computed tomography. Calcifications associated with bone abnormalities showed no acoustic shadowing at ultrasonography, favoring the hypothesis of resorption phase of the disease. Conclusion Preliminary results of the present study suggest that ultrasonography can identify bone abnormalities secondary to rotator cuff calcific tendinopathy, particularly the presence of cortical bone erosion. PMID:26811551
dos S Luz, Diandra; de S Ourique, Fernanda; Scarparo, Roberta K; Vier-Pelisser, Fabiana V; Morgental, Renata D; Waltrick, Silvana B G; de Figueiredo, José A P
2015-01-01
The aim of this preliminary study was to evaluate the desirability of alternative models of artificial teeth versus extracted natural teeth for use in preclinical dental education. Specifically, the study was designed to compare the preparation time and perceptions of difficulty of undergraduate dental students and endodontists in carrying out root canal preparations on resin models (both clear and opaque) and extracted natural teeth. Twenty participants-ten fifth-year students at a Brazilian dental school and ten endodontists with at least five years' experience in the specialty-performed root canal instrumentation on two samples of each model. Preparation times were recorded, and the participants completed a questionnaire about the anatomical and physical characteristics of these models. The results showed that the time required for performing endodontic procedures in the natural teeth was higher than in the alternative models. The perceptions of the students and specialists regarding some topics on the questionnaire were significantly different. The students had more positive opinions about artificial teeth made of opaque resin, while the specialists had more positive opinions about simulated root canals in clear resin blocks. This study suggests that neither of the alternative models fulfilled requirements to replace natural teeth in endodontic teaching; improvements are still necessary to accomplish this goal.
Tam, Chi Keung; McGrath, Colman Patrick; Ho, Samuel Mun Yin; Pow, Edmond Ho Nang; Luk, Henry Wai Kuen; Cheung, Lim Kwong
2014-01-01
Introduction. The psychosocial and quality of life (QoL) of patients with deformed or missing ears are frequently compromised. The aim of this study is to develop innovative techniques using CAD/CAM technology in prosthetic auricular rehabilitation and provide improvement in the treatment outcomes, including their psychology and QoL. Methods. This is a preliminary clinical cohort study. Six patients requesting for auricular reconstruction were recruited and rehabilitated with implant-supported prosthesis using CAD/CAM technology. Different treatment outcomes including QoL and psychological changes were assessed at different time points. Results. A significant reduction in severity of depressive symptoms (P = 0.038) and an improving trend of satisfaction with life were found at 1 year postoperatively when compared with the preoperative findings. The domain scores in ‘‘Body image”, ‘‘Family/friends/strangers”, and ‘‘Mood” were also significantly higher (P < 0.05) at 1 year postoperatively than 1 week postoperatively. However, only 50% of the patients wear their auricular prosthesis regularly. Conclusion. This preliminary study has confirmed that implant-supported auricular prosthesis could induce improvement in the psychology and QoL with statistically significant differences in the domains of the body image, social interaction, and mood. Our present findings can inform research design and hypotheses generation of future studies. PMID:24799904
A preliminary study on the potential of manuka honey and platelet-rich plasma in wound healing.
Sell, Scott A; Wolfe, Patricia S; Spence, Andrew J; Rodriguez, Isaac A; McCool, Jennifer M; Petrella, Rebecca L; Garg, Koyal; Ericksen, Jeffery J; Bowlin, Gary L
2012-01-01
Aim. The purpose of this study was to determine the in vitro response of cells critical to the wound healing process in culture media supplemented with a lyophilized preparation rich in growth factors (PRGF) and Manuka honey. Materials and Methods. This study utilized cell culture media supplemented with PRGF, as well as whole Manuka honey and the medical-grade Medihoney (MH), a Manuka honey product. The response of human fibroblasts (hDF), macrophages, and endothelial cells (hPMEC) was evaluated, with respect to cell proliferation, chemotaxis, collagen matrix production, and angiogenic potential, when subjected to culture with media containing PRGF, MH, Manuka honey, and a combination of PRGF and MH. Results. All three cell types demonstrated increases in cellular activity in the presence of PRGF, with further increases in activity seen in the presence of PRGF+MH. hDFs proved to be the most positively responsive cells, as they experienced enhanced proliferation, collagen matrix production, and migration into an in vitro wound healing model with the PRGF+MH-supplemented media. Conclusion. This preliminary in vitro study is the first to evaluate the combination of PRGF and Manuka honey, two products with the potential to increase regeneration individually, as a combined product to enhance dermal regeneration.
A Preliminary Study on the Potential of Manuka Honey and Platelet-Rich Plasma in Wound Healing
Sell, Scott A.; Wolfe, Patricia S.; Spence, Andrew J.; Rodriguez, Isaac A.; McCool, Jennifer M.; Petrella, Rebecca L.; Garg, Koyal; Ericksen, Jeffery J.; Bowlin, Gary L.
2012-01-01
Aim. The purpose of this study was to determine the in vitro response of cells critical to the wound healing process in culture media supplemented with a lyophilized preparation rich in growth factors (PRGF) and Manuka honey. Materials and Methods. This study utilized cell culture media supplemented with PRGF, as well as whole Manuka honey and the medical-grade Medihoney (MH), a Manuka honey product. The response of human fibroblasts (hDF), macrophages, and endothelial cells (hPMEC) was evaluated, with respect to cell proliferation, chemotaxis, collagen matrix production, and angiogenic potential, when subjected to culture with media containing PRGF, MH, Manuka honey, and a combination of PRGF and MH. Results. All three cell types demonstrated increases in cellular activity in the presence of PRGF, with further increases in activity seen in the presence of PRGF+MH. hDFs proved to be the most positively responsive cells, as they experienced enhanced proliferation, collagen matrix production, and migration into an in vitro wound healing model with the PRGF+MH-supplemented media. Conclusion. This preliminary in vitro study is the first to evaluate the combination of PRGF and Manuka honey, two products with the potential to increase regeneration individually, as a combined product to enhance dermal regeneration. PMID:23304152
Nogueira-Barbosa, Marcello H; Gregio-Junior, Everaldo; Lorenzato, Mario Muller
2015-01-01
The present study was aimed at investigating bone involvement secondary to rotator cuff calcific tendonitis at ultrasonography. Retrospective study of a case series. The authors reviewed shoulder ultrasonography reports of 141 patients diagnosed with rotator cuff calcific tendonitis, collected from the computer-based data records of their institution over a four-year period. Imaging findings were retrospectively and consensually analyzed by two experienced musculoskeletal radiologists looking for bone involvement associated with calcific tendonitis. Only the cases confirmed by computed tomography were considered for descriptive analysis. Sonographic findings of calcific tendinopathy with bone involvement were observed in 7/141 (~ 5%) patients (mean age, 50.9 years; age range, 42-58 years; 42% female). Cortical bone erosion adjacent to tendon calcification was the most common finding, observed in 7/7 cases. Signs of intraosseous migration were found in 3/7 cases, and subcortical cysts in 2/7 cases. The findings were confirmed by computed tomography. Calcifications associated with bone abnormalities showed no acoustic shadowing at ultrasonography, favoring the hypothesis of resorption phase of the disease. Preliminary results of the present study suggest that ultrasonography can identify bone abnormalities secondary to rotator cuff calcific tendinopathy, particularly the presence of cortical bone erosion.
Kristjánsson, Kristján
2015-10-01
Phronesis has become a buzzword in contemporary medical ethics. Yet, the use of this single term conceals a number of significant conceptual controversies based on divergent philosophical assumptions. This paper explores three of them: on phronesis as universalist or relativist, generalist or particularist, and natural/painless or painful/ambivalent. It also reveals tensions between Alasdair MacIntyre's take on phronesis, typically drawn upon in professional ethics discourses, and Aristotle's original concept. The paper offers these four binaries as a possible analytical framework for classifying and evaluating accounts of phronesis in the medical ethics literature. It argues that to make sense of phronesis as a putative ideal in professional medical ethics--for example, with the further aim of crafting interventions to cultivate phronesis in medical ethics education--the preliminary question of which conception of phronesis is most serviceable for the aim in question needs to be answered. The paper identifies considerable lack of clarity in the current discursive field on phronesis and suggests how that shortcoming can be ameliorated.
Preliminary analysis of EUSO—TA data
NASA Astrophysics Data System (ADS)
Fenu, F.; Piotrowski, L. W.; Shin, H.; Jung, A.; Bacholle, S.; Bisconti, F.; Capel, F.; Eser, J.; Kawasaki, Y.; Kuznetsov, E.; Larsson, O.; Mackovjak, S.; Miyamoto, H.; Plebaniak, Z.; Prevot, G.; Putis, M.; Shinozaki, K.; Adams, J.; Bertaina, M.; Bobik, P.; Casolino, M.; Matthews, J. N.; Ricci, M.; Wiencke, L.;
2016-05-01
The EUSO-TA detector is a pathfinder for the JEM-EUSO project and is currently installed in Black Rock Mesa (Utah) on the site of the Telescope Array fluorescence detectors. Aim of this experiment is to validate the observation principle of JEM-EUSO on air showers measured from ground. The experiment gets data in coincidence with the TA triggers to increase the likelihood of cosmic ray detection. In this framework the collaboration is also testing the detector response with respect to several test events from lasers and LED flashers. Moreover, another aim of the project is the validation of the stability of the data acquisition chain in real sky condition and the optimization of the trigger scheme for the rejection of background. Data analysis is ongoing to identify cosmic ray events in coincidence with the TA detector. In this contribution we will show the response of the EUSO-TA detector to all the different typologies of events and we will show some preliminary results on the trigger optimization performed on such data.
Okuda, Tomoko; Asano, Kenichi; Numata, Noriko; Hirano, Yoshiyuki; Yamamoto, Tetsuya; Tanaka, Mari; Matsuzawa, Daisuke; Shimizu, Eiji; Iyo, Masaomi; Nakazato, Michiko
2017-01-01
Set-shifting (SS) difficulties and weak central coherence (CC) are commonly associated with autism spectrum disorders (ASD). Cognitive remediation therapy (CRT) aims to improve such cognitive processing; however, there are no reports on CRT for patients with ASD. This pilot study aimed to provide preliminary evidence to support the use of CRT for individuals with ASD and provide data to inform future studies. Nineteen individuals with ASD were recruited and administered a series of neuropsychological and questionnaire measures to examine cognitive function and clinical outcomes such as anxiety and depression. Participants received CRT, and cognitive function and clinical variables were re-evaluated at postintervention and after 3 months. The participants demonstrated significant improvement in CC and anxiety at postintervention, which was maintained at 3-month follow-up. Although SS scores had improved with a large effect size, this was not statistically significant. CRT improved CC and anxiety scores for individuals with ASD, suggesting that CRT is an effective treatment for individuals with ASD.
Vranceanu, Ana-Maria; Merker, Vanessa L; Plotkin, Scott R; Park, Elyse R
2014-10-01
NF1, NF2, and Schwannomatosis are incurable tumor suppressor syndromes associated with poor quality of life. The aim of this study was to determine the feasibility, acceptability, and preliminary efficacy of an NF adapted, 8-week group mind body skills based intervention, the relaxation response resiliency program (3RP) aimed at improving resiliency and increasing satisfaction with life. Patients seen at MGH's Neurofibromatosis Clinic were offered participation if they described difficulties coping to a treating physician. Participants completed measures of life satisfaction, resiliency, stress, mood, lifestyle, pain, post-traumatic growth and mindfulness at baseline and after completing the 3RP program. The intervention had relative feasible enrollment rate (48% rate, 32 out of 67 of patients signing the informed consent form). However, out of the 32 patients who signed the informed consent, only 20 started the study (62.5%) and only 16 completed it (50%), suggesting problems with feasibility. The main reason cited for non-participation was burden of travel to the clinic. The intervention was highly acceptable, as evidenced by an 80% completion rate (16/20). Paired t tests showed significant improvement in resiliency, satisfaction with life, depression, stress, anxiety, mindfulness and post traumatic growth, with effect sizes ranging from 0.73-1.33. There was a trend for significance for improvement in somatization and sleepiness (p = 0.06), with effect sizes of 0.54-0.92 respectively. Statistically nonsignificant improvement was observed in all other measures, with effect sizes small to medium. In sum, the 3RP was found to be relatively feasible, highly acceptable and preliminary efficacious in decreasing symptom burden in this population, supporting the need of a randomized controlled trial.
Pallant, Julie F; Misajon, RoseAnne; Bennett, Elizabeth; Manderson, Lenore
2006-01-01
Background The aim of this study was to develop and conduct preliminary validation of the Perceived Impact of Problem Profile (PIPP). Based on the biopsychosocial model of health and functioning, the PIPP was intended as a generic research and clinical measurement tool to assess the impact and distress of health conditions from the individuals' perspective. The ICF classification system was used to guide the structure of the PIPP with subscales included to assess impact on self-care, mobility, participation, relationships and psychological well-being. While the ICF focuses on the classification of objective health and health related status, the PIPP broadens this focus to address the individuals' subjective experience of their health condition. Methods An item pool of 23 items assessing both impact and distress on five key domains was generated. These were administered to 169 adults with mobility impairment. Rasch analysis using RUMM2020 was conducted to assess the psychometric properties of each set of items. Preliminary construct validation of the PIPP was performed using the EQ5D. Results For both the Impact and Distress scales of the PIPP, the five subscales (Self-care, Mobility, Participation, Relationships, and Psychological Well-being) showed adequate psychometric properties, demonstrating fit to the Rasch model. All subscales showed adequate person separation reliability and no evidence of differential item functioning for sex, age, educational level or rural vs urban residence. Preliminary validity testing using the EQ5D items provided support for the subscales. Conclusion This preliminary study, using a sample of adults with mobility impairment, provides support for the psychometric properties of the PIPP as a potential clinical and research measurement tool. The PIPP provides a brief, but comprehensive means to assess the key ICF components, focusing on the individuals' perspective of the impact and distress caused by their health condition. Further validation of its use across different health conditions and varying cultural settings is required. PMID:16808842
Developing a preliminary ‘never event’ list for general practice using consensus-building methods
de Wet, Carl; O’Donnell, Catherine; Bowie, Paul
2014-01-01
Background The ‘never event’ concept has been implemented in many acute hospital settings to help prevent serious patient safety incidents. Benefits include increasing awareness of highly important patient safety risks among the healthcare workforce, promoting proactive implementation of preventive measures, and facilitating incident reporting. Aim To develop a preliminary list of never events for general practice. Design and setting Application of a range of consensus-building methods in Scottish and UK general practices. Method A total of 345 general practice team members suggested potential never events. Next, ‘informed’ staff (n =15) developed criteria for defining never events and applied the criteria to create a list of candidate never events. Finally, UK primary care patient safety ‘experts’ (n = 17) reviewed, refined, and validated a preliminary list via a modified Delphi group and by completing a content validity index exercise. Results There were 721 written suggestions received as potential never events. Thematic categorisation reduced this to 38. Five criteria specific to general practice were developed and applied to produce 11 candidate never events. The expert group endorsed a preliminary list of 10 items with a content validity index (CVI) score of >80%. Conclusion A preliminary list of never events was developed for general practice through practitioner experience and consensus-building methods. This is an important first step to determine the potential value of the never event concept in this setting. It is now intended to undertake further testing of this preliminary list to assess its acceptability, feasibility, and potential usefulness as a safety improvement intervention. PMID:24567655
Altamura, A C; Salvadori, Daniele; Madaro, Donato; Santini, Annalisa; Mundo, Emanuela
2003-09-01
The literature on the use of quetiapine for the treatment of bipolar disorder (BD) is limited to case reports, and there are no systematic studies on the efficacy of quetiapine in the prophylactic treatment of BD. The aim of the present study was to compare the efficacy of flexible doses of quetiapine and well established mood stabilizers in the maintenance treatment of BD. Twenty-eight DSM-IV BD outpatients were consecutively recruited into the study and were randomized to receive one of two open-label treatments, with quetiapine or classical mood stabilizers at flexible doses for 12 months. Clinical assessment was carried out using BPRS, CGI, YMRS and the 21-item HAM-D at baseline (T0) and every 2 months until the end of the study. ANOVAs with repeated measures were applied to the rating scale scores considering the time and the treatment group as main factors. All patients experienced a significant improvement on the BPRS, CGI and HAM-D scores, with no significant side-effects and a good compliance. This study should be considered preliminary given the small sample size investigated and the open-label design. If these results will be replicated on larger samples and in controlled studies, there could be relevant implications for the use of quetiapine as an alternative maintenance treatment for BD.
Kahn, Didier
2010-11-01
This article provides a preliminary description of medieval and early modern alchemical poetry composed in Latin and in the principal vernacular languages of western Europe. It aims to distinguish the various genres in which this poetry flourished, and to identify the most representative aspects of each cultural epoch by considering the medieval and early modern periods in turn. Such a distinction (always somewhat artificial) between two broad historical periods may be justified by the appearance of new cultural phenomena that profoundly modified the character of early modern alchemical poetry: the ever-increasing importance of the prisca theologia, the alchemical interpretation of ancient mythology, and the rise of neo-Latin humanist poetry. Although early modern alchemy was marked by the appearance of new doctrines (notably the alchemical spiritus mundi and Paracelsianism), alchemical poetry was only superficially modified by criteria of a scientific nature, which therefore appear to be of lesser importance. This study falls into two parts. Part I provides a descriptive survey of extant poetry, and in Part II the results of the survey are analysed in order to highlight such distinctive features as the function of alchemical poetry, the influence of the book market on its evolution, its doctrinal content, and the question of whether any theory of alchemical poetry ever emerged. Part II is accompanied by an index of the authors and works cited in both parts.
Capability of microalgae for local saline sewage treatment towards biodiesel production
NASA Astrophysics Data System (ADS)
Wu, K.-C.; Yau, Y.-H.; Ho, K.-C.
2017-08-01
Seawater flushing was introduced in Hong Kong since 1950’s. High salinity has an inhibitory effect on nitrification and biological phosphorus uptake of microorganisms. Therefore, saline sewage has impact on traditional biological wastewater treatment. Saline conditions of domestic wastewater then pose opportunity to use algal technology in wastewater treatment. During the treatment (phycoremediation), biodiesel can be produced. This study aims to give an in-depth investigation and development on application of local microalgal strains on biodiesel production. Dunaliella tertiolecta was selected the appropriate algal species with high potential for phycoremediation then biodiesel production. D.tertiolecta was further investigated by optimizing its growth in different process condition in preliminary effluent as based medium. The optimized process condition were acclimated culture with medium initial cell number (5.0 ×105 cells mL-1), under 5% CO2 aerations in preliminary effluent adjust to 15 psu (denoting practical salinity unit). Results showed that lipid content increased from 30.2% to 42%, and biomass productivity reached 463.3 mg L-1day-1 by Fatty acid Methyl Ester (FAME) profile was found for biodiesel production in optimized stage. The treatment period of preliminary effluent was shortened from 15d in original design (unacclimated culture, low initial cell number (5.0 ×105 cells mL-1), without CO2 aeration) to 4d.
[Preventable drug-related morbidity: determining valid indicators for primary care in Portugal].
Guerreiro, Mara Pereira; Cantrill, Judith A; Martins, Ana Paula
2007-01-01
Preventable drug-related morbidity (PDRM) indicators are operational measures of therapeutic risk management. These clinical indicators, which cover a wide range of drugs, combine process and outcome in the same instrument. They were developed in the US and have been validated for primary care settings in the US, UK and Canada. This study is part of a research programme; it aimed to determine a valid set of PDRM indicators for adult patients in primary care in Portugal. Face validity of 61 US and UK-derived indicators translated to Portuguese was preliminarily determined by means of a postal questionnaire using a purposive sample of four Portuguese pharmacists with different backgrounds. Preliminary content validity of indicators approved in the previous stage was determined by cross-checking each definition of PDRM with standard drug information sources in Portugal. Face and content validity of indicators yielded by preliminary work were then established by a 37 expert panel (20 community pharmacists and 17 general practitioners) using a two-round Delphi survey. Data were analysed using SPSS release 11.5. Nineteen indicators were ruled out in preliminary validation. Changes were made in the content of eight of the remaining 42 indicators; these were related to differences in the drugs being marketed and patterns of drug monitoring between countries. Thirty-five indicators were consensus approved as PDRM for adult patients in Portuguese primary care by the Delphi panel.
NASA Astrophysics Data System (ADS)
Iovea, M.; Creed, J.; Perin, E.; Neagu, M.; Mateiasi, G.
2009-02-01
The aim of this study was to conduct a preliminary check of a new method for measuring the 3D catheter position based on only one X-Ray view (image) and a simple pre-calibration procedure for catheters that could be equipped with high-opacity equal-spaced markers. The application chosen for this experiment is the targeted delivery of cell based therapeutic via a transendocardial retrograde approach into the left ventricle. This approach has shown promising therapeutic retention data when injected directly into the myocardial tissue, but lacks in the ability of the user to confidently manipulate the catheter within the left ventricle cavity space under traditional fluoroscopic guidance using a needle based catheter. The need for a new technique arose from the potential for increased safety and therapeutic efficacy by improving the targeting of the agent. The new technique, destined for Image guided catheter navigation systems for cardiac interventions, is based on a measurement of the marker's size and distance between them and followed by a comparison with the referenced catheter position. Preliminary experiments made with a simple phantom are presented, emphasizing the ability of the new technique in measuring the markers and the catheter tip 3D position. An overall maximum error in positioning markers and catheter tip below 12% has been obtained, yielding a promising result for continuing the future work of improving the algorithm accuracy.
Kaufman, Jessica; Ryan, Rebecca; Lewin, Simon; Bosch-Capblanch, Xavier; Glenton, Claire; Cliff, Julie; Oyo-Ita, Angela; Muloliwa, Artur Manuel; Oku, Afiong; Ames, Heather; Rada, Gabriel; Cartier, Yuri; Hill, Sophie
2017-08-20
Communication interventions for childhood vaccination are promising strategies to address vaccine hesitancy, but current research is limited by the outcomes measured. Most studies measure only vaccination-related outcomes, with minimal consideration of vaccine hesitancy-relevant intermediate outcomes. This impedes understanding of which interventions or elements are effective. It is also unknown which outcomes are important to the range of stakeholders affected by vaccine hesitancy. Outcome selection shapes the evidence base, informing future interventions and trials, and should reflect stakeholder priorities. Therefore, our aim was to identify which outcome domains (i.e. broad outcome categories) are most important to different stakeholders, identifying preliminary core outcome domains to inform evaluation of three common vaccination communication types: (i) communication to inform or educate, (ii) remind or recall, and (iii) enhance community ownership. We conducted a two-stage online Delphi survey, involving four stakeholder groups: parents or community members, healthcare providers, researchers, and government or non-governmental organisation representatives. Participants rated the importance of eight outcome domains for each of the three communication types. They also rated specific outcomes within one domain ("attitudes or beliefs") and provided feedback about the survey. Collectively, stakeholder groups prioritised outcome domains differently when considering the effects of different communication types. For communication that aims to (i) inform or educate, the most important outcome domain is "knowledge or understanding"; for (ii) reminder communication, "vaccination status and behaviours"; and for (iii) community engagement communication, "community participation". All stakeholder groups rated most outcome domains as very important or critical. The highest rated specific outcome within the "attitudes or beliefs" domain was "trust". This Delphi survey expands the field of core outcomes research and identifies preliminary core outcome domains for measuring the effects of communication about childhood vaccination. The findings support the argument that vaccination communication is not a single homogenous intervention - it has a range of purposes, and vaccination communication evaluators should select outcomes accordingly. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.
Development and reliability of a preliminary Foot Osteoarthritis Magnetic Resonance Imaging Score
Halstead, Jill; Martín-Hervás, Carmen; Hensor, Elizabeth MA; McGonagle, Dennis; Keenan, Anne-Maree
2017-01-01
Objective Foot osteoarthritis (OA) is very common but under-investigated musculoskeletal condition and there is little consensus as to common MRI imaging features. The aim of this study was to develop a preliminary foot OA MRI score (FOAMRIS) and evaluate its reliability. Methods This preliminary semi-quantitative score included the hindfoot, midfoot and metatarsophalangeal joints. Joints were scored for joint space narrowing (JSN, 0-3), osteophytes (0-3), joint effusion-synovitis and bone cysts (present/absent). Erosions and bone marrow lesions (BMLs) were scored (0-3) and BMLs were evaluated adjacent to entheses and at sub-tendon sites (present/absent). Additionally, tenosynovitis was scored (0-3) and midfoot ligament pathology was scored (present/absent). Reliability was evaluated in 15 people with foot pain and MRI-detected OA using 3.0T MRI multi-sequence protocols and assessed using intraclass correlation coefficients (ICC) as an overall score and per anatomical site (see supplementary data). Results Intra-reader agreement (ICC) was generally good to excellent across the foot in joint features (JSN 0.94, osteophytes 0.94, effusion-synovitis 0.62 and cysts 0.93), bone features (BML 0.89, erosion 0.78, BML-entheses 0.79, BML sub-tendon 0.75) and soft-tissue features (tenosynovitis 0.90, ligaments 0.87). Inter-reader agreement was lower for joint features (JSN 0.60, osteophytes 0.41, effusion-synovitis 0.03) and cysts 0.65, bone features (BML 0.80, erosion 0.00, BML-entheses 0.49, BML sub-tendon -0.24) and soft-tissue features (tenosynovitis 0.48, ligaments 0.50). Conclusion This preliminary FOAMRIS demonstrated good intra-reader reliability and fair inter-reader reliability when assessing the total feature scores. Further development is required in cohorts with a range of pathologies and to assess the psychometric measurement properties. PMID:28572462
Miodownik, Chanoch; Lerner, Vladimir; Vishne, Tali; Sela, Ben-Ami; Levine, Joseph
2007-01-01
Vitamin B6 plays an essential role in the normal functioning of the central nervous system. Normal homocysteine (Hcy) serum level is maintained by remethylation of Hcy to methionine by enzymes that require folic acid and vitamin B12 and by catabolism to cysteine by a vitamin B6-dependent enzyme. These findings may be consistent with the hypothesis that the vitamin B6 status may influence plasma Hcy levels. The aims of this preliminary study were (1) to determine whether a correlation exists between Hcy and vitamin B6 levels in patients with schizophrenia and schizoaffective disorders and (2) to investigate whether treatment with high-dose vitamin B6 may reduce Hcy levels in these patients. In this preliminary study, we enrolled 11 patients with schizophrenia or schizoaffective disorders (7 men and 4 women; mean age +/- SD, 50 +/- 12 years) receiving high doses of vitamin B6 treatment (1200 mg/d) for 12 weeks. Blood samples for the assessment of pyridoxal-5-phosphate and Hcy serum levels were obtained at baseline and after 12 weeks of treatment. Age was significantly positively correlated with Hcy levels at baseline (r = 0.392, P = 0.004). All other parameters, including diagnosis, disease duration, and pyridoxal-5-phosphate serum level, were not correlated with Hcy serum levels at baseline. After vitamin B6 treatment, Hcy serum levels significantly decreased (14.2 +/- 3.4 vs. 11.8 +/- 2.0 micromol/L, respectively, t = 2.679, P = 0.023); this decrease being statistically significant in men but not in women. High doses of vitamin B6 lead to a decrease in Hcy serum level in male patients with schizophrenia or schizoaffective disorder.
Tracer element for indoor PM2.5 in China migrated from outdoor
NASA Astrophysics Data System (ADS)
Ji, Wenjing; Li, Hongyu; Zhao, Bin; Deng, Furong
2018-03-01
Sulfur and nickel have been widely used as tracers of outdoor PM2.5 (particulate matter with an aerodynamic diameter ≤ 2.5 μm) in the United States and Europe; however, their feasibility as tracers has not been verified yet in China. We aim to verify whether sulfur or nickel could be used as a tracer element and, if not, to identify a suitable tracer element for outdoor PM2.5 in China. We conduct two types of experiments, namely, preliminary and main-study experiments. We analyze 102 pairs of indoor and outdoor PM2.5 samples in Beijing. The correlation between the I/O (indoor/outdoor) ratio of an element and the I/O ratio of total PM2.5 is one of the criteria used to test whether this element can be used as a tracer element. The average concentrations of nickel are found to be below the detection limits in both preliminary and main-study tests. Thus, nickel cannot be used as a tracer element in China. Based on the correlations of elemental I/O ratios and the I/O ratio of total PM2.5 in the preliminary and main-study tests, sulfur also cannot be used as a tracer element; however, it should be feasible to use iron as a tracer element in Beijing according to the test results. The estimated infiltration factor obtained by using iron as tracer is extremely consistent with the calculations based on the mass balance model. In summary, iron is found to be more suitable as a tracer for outdoor PM2.5 in Beijing than sulfur or nickel.
Ayanwuyi, Lydia O.; Kwanashie, Helen O.; Hussaini, Isa M.; Yaro, Abdullahi H.
2016-01-01
Background: Leonotis nepetifolia Linn (Lamiaceae) is used in traditional medicine for its calming (tranquilizing) effects. The aim of this study was to determine whether there is any scientific justification for this use. To achieve this purpose, we investigated the behavioural effects of the methanol extract of Leonotis nepetifolia stem (37.5, 75 and 150 mg/kg) in mice. Methods: Acute toxicity studies were carried out on the methanol stem extract of Leonotis nepetifolia to determine the LD50. The behavioural tests employed were diazepam-induced sleep onset and duration, hole board assay for exploratory activity, mouse beam walk assay for motor coordination, and the staircase test for the detection of anxiolytic compounds. Preliminary phytochemical screening was also carried out on the extract. Results: The intraperitoneal LD50 value was found to be 3.8 g/kg. The results showed that the extract significantly prolonged the duration of diazepam-induced sleep at the highest dose (150 mg/kg). There was no observable effect on exploratory activity and motor coordination at the doses tested (37.5, 75 and 150 mg/kg). The extract, however, at 150 mg/kg elicited a significant decrease in the number of rearings in the staircase test, an effect also observed in the group of mice injected with an anxiolytic dose of diazepam. The preliminary phytochemical screening revealed the presence of alkaloids, saponins, glycosides and triterpenoids. Conclusion: The results obtained suggest that the crude methanol extract of Leonotis nepetifolia stem possesses some biologically active constituents with potential anxiolytic activity and thus may justify its traditional use as a tranquilizer. PMID:28852715
Omura, Yuri; Kanazawa, Manabu; Sato, Daisuke; Kasugai, Shohei; Minakuchi, Shunsuke
2016-07-01
The aim of this preliminary study is to compare patient-reported outcomes between immediately and conventionally loaded mandibular two-implant overdentures retained by magnetic attachments. Nineteen participants with edentulous mandibles were randomly assigned into either an immediate loading group (immediate group) or a conventional loading group (conventional group). Each participant received 2 implants in the inter-foraminal region by means of flapless surgery. Prostheses in the immediate and conventional groups were loaded using magnetic attachments on the same day as implant placement or 3 months after surgery, respectively. All participants completed questionnaires (the Japanese version of the Oral Health Impact Profile for edentulous [OHIP-EDENT-J], the patient's denture assessment [PDA], and general satisfaction) before implant placement (baseline) and 1, 2, 3, 4, 5, 6, and 12 months after surgery. The median differences between baseline and each monthly score were compared using the Mann-Whitney U test. The differences in median and 95% confidence interval between two groups were analyzed. The immediate group showed slightly lower OHIP-EDENT-J summary score at 1 and 3 months than the conventional group (P=0.09). In the lower denture domain of PDA, the immediate group showed a statistically higher score at 3 months (P=0.04). There was no statistically significant difference in general satisfaction between the two groups. Based on this preliminary study, immediate loading of mandibular two-implant overdentures with magnetic attachments tends to improve oral health-related quality of life and patient assessment earlier than observed with a conventional loading protocol. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
A Preliminary Review of Fatigue Among Rail Staff
Fan, Jialin; Smith, Andrew P.
2018-01-01
Background: Fatigue is a severe problem in the rail industry, which may jeopardize train crew's health and safety. Nonetheless, a preliminary review of all empirical evidence for train crew fatigue is still lacking. The aim of the present paper is, therefore, to provide a preliminary description of occupational fatigue in the rail industry. This paper reviews the literature with the research question examining the risk factors associated with train crew fatigue, covering both papers published in refereed journals and reports from trade organizations and regulators. It assesses the progress of research on railway fatigue, including research on the main risk factors for railway fatigue, the association between fatigue and railway incidents, and how to better manage fatigue in the railway industry. Methods: Systematic searches were performed in both science and industry databases. The searches considered studies published before August 2017. The main exclusion criterion was fatigue not being directly measured through subjective or objective methods. Results: A total of 31 studies were included in the main review. The causes of fatigue included long working hours, heavy workload, early morning or night shifts, and insufficient sleep. Poor working environment, particular job roles, and individual differences also contributed to fatigue. Conclusion: Fatigue in the rail industry includes most of the features of occupational fatigue, and it is also subject to industry-specific factors. The effect of fatigue on well-being and the fatigued population in the railway industry are still not clear. Future studies can consider associations between occupational risk factors and perceived fatigue by examining the prevalence of fatigue and identifying the potential risk factors in staff within the railway industry. PMID:29867630
Remotely-Sensed Detection of Foreclosure Effects on Residential Landscapes
NASA Astrophysics Data System (ADS)
Cutts, B.; Minn, M.; Pavlovic, N. R.; Greenberg, J. A.; Fraterrigo, J.; Turner, V. K.
2014-12-01
This project aims to understand whether the foreclosure crisis of 2007-2010 led to change in yard management with consequences for property and neighborhood land cover. By triangulating across analyses that vary in spatial and temporal resolution, this study examines whether foreclosure has resulted in changes in household and neighborhood vegetation structure. One common hypothesis is that the of financial distress is a reduction in lawn management (mowing, irrigating, and fertilizing ) due to economic constraint, vacancy or abandonment. However, changes in these practices differ across space as they are mediated by individual idiosyncrasies as well as complex social norms encoded in formal and informal institutions. The aim of our broader research project is to gain understanding of how foreclosure changes yard management within the context of these institutions. This poster presents preliminary results of analyses that aim to understand the relationship between foreclosure and land cover change in Maricopa County (Phoenix), Arizona. We synthesize foreclosure data with other social data sources focused on demographics, property characteristics, and vacancy to quantify both general and spatially dependent signatures of foreclosure in remotely-sensed NDVI data from MODIS and LANDSAT. Through results from multiple sources of data, we aim to isolate and describe signals that can be correlated with housing distress and foreclosure-induced vacancy. Arizona is analytically advantageous as area with an arid climate where the vegetation changes resulting from cessation of lawn maintenance are often dramatic and clearly observable. Our preliminary analysis indicates that there are specific NDVI signatures reflecting differing landscape-maintenance responses to foreclosure, supporting our central thesis that foreclosure influences land cover. These results provide a foundation upon which we will engage in both detailed investigation of the environmental effects of this phenomenon, as well as the social drivers that have result in the dramatic differences in behavior across space. The broader value of this project is to understand the short and long-term influences of foreclosure over human-environment relationships in urban and suburban developments.
Roncero, Octavio; Aguado, Alfredo; Batista-Romero, Fidel A; Bernal-Uruchurtu, Margarita I; Hernández-Lamoneda, Ramón
2015-03-10
A variant of the density difference driven optimized embedding potential (DDD-OEP) method, proposed by Roncero et al. (J. Chem. Phys. 2009, 131, 234110), has been applied to the calculation of excited states of Br2 within small water clusters. It is found that the strong interaction of Br2 with the lone electronic pair of the water molecules makes necessary to optimize specific embedding potentials for ground and excited electronic states, separately and using the corresponding densities. Diagnosis and convergence studies are presented with the aim of providing methods to be applied for the study of chromophores in solution. Also, some preliminary results obtained for the study of electronic states of Br2 in clathrate cages are presented.
NASA Astrophysics Data System (ADS)
Poser, Kathrin; Peters, Steef; Hommersom, Annelies; Giardino, Claudia; Bresciani, Mariano; Cazzaniga, Ilaria; Schenk, Karin; Heege, Thomas; Philipson, Petra; Ruescas, Ana; Bottcher, Martin; Stelzer, Kerstin
2015-12-01
The GLaSS project develops a prototype infrastructure to ingest and process large amounts of Sentinel-2 and Sentinel-3 data for lakes and reservoirs. To demonstrate the value of satellite observations for the management of aquatic ecosystems, global case studies are performed addressing different types of lakes with their respective problems and management questions. One of these case studies is concentrating on deep clear lakes worldwide. The aim of this case study is to evaluate trends of chlorophyll-a concentrations (Chl-a) as a proxy of the trophic status based on the MERIS full resolution data archive. Some preliminary results of this case study are presented here.
Yoga-Enhanced Cognitive Behavioral Therapy (Y-CBT) for Anxiety Management: A Pilot Study
Khalsa, Manjit K.; Greiner-Ferris, Julie M.; Hofmann, Stefan G.; Khalsa, Sat Bir S.
2014-01-01
Cognitive behavioral therapy is an effective treatment for generalized anxiety disorder (GAD), but there is still room for improvement. The aim of the present study was to examine the potential benefit of enriching cognitive behavioral therapy (CBT) with Kundalini Yoga (Y-CBT). Participants consisted of treatment resistant clients at a community mental health clinic. A total of 32 participants enrolled in the study and 22 completed the program. After the Y-CBT intervention, pre-post comparisons showed statistically significant improvements in state and trait anxiety, depression, panic, sleep, and quality of life. Results from this preliminary study suggest that Y-CBT may have potential as a promising treatment for those suffering from GAD. PMID:24804619
Preliminary design study for an atomospheric science facility
NASA Technical Reports Server (NTRS)
Hutchison, R.
1972-01-01
The activities and results of the Atmospheric Science Facility preliminary design study are reported. The objectives of the study were to define the scientific goals, to determine the range of experiment types, and to develop the preliminary instrument design requirements for a reusable, general purpose, optical research facility for investigating the earth's atmosphere from a space shuttle orbital vehicle.
Agreli, Heloise F; Peduzzi, Marina; Bailey, Christopher
2017-03-01
Relational and organisational factors are key elements of interprofessional collaboration (IPC) and team climate. Few studies have explored the relationship between IPC and team climate. This article presents a study that aimed to explore IPC in primary healthcare teams and understand how the assessment of team climate may provide insights into IPC. A mixed methods study design was adopted. In Stage 1 of the study, team climate was assessed using the Team Climate Inventory with 159 professionals in 18 interprofessional teams based in São Paulo, Brazil. In Stage 2, data were collected through in-depth interviews with a sample of team members who participated in the first stage of the study. Results from Stage 1 provided an overview of factors relevant to teamwork, which in turn informed our exploration of the relationship between team climate and IPC. Preliminary findings from Stage 2 indicated that teams with a more positive team climate (in particular, greater participative safety) also reported more effective communication and mutual support. In conclusion, team climate provided insights into IPC, especially regarding aspects of communication and interaction in teams. Further research will provide a better understanding of differences and areas of overlap between team climate and IPC. It will potentially contribute for an innovative theoretical approach to explore interprofessional work in primary care settings.
Richardson, Cele; Gradisar, Michael; Pulford, Amanda
2015-01-01
The present preliminary study aimed to shed light on the mechanisms underlying the development of insomnia. An analogue stressor (i.e., trauma video) was used to prevent presleep cognitive de-arousal. Subsequent changes in nocturnal sleep and sleep-related attentional processing were examined. Thirty-four participants were randomly assigned to either a cognitive arousal (trauma video; age: M = 22.9, SD = 4.3, 6 male, 11 female) or control (pleasant video; age: M = 23.8, SD = 5.8, 7 male, 10 female) condition. Although no significant differences were found for presleep cognitive de-arousal (p = .39), the cognitive arousal group experienced a significant worsening in sleep latency (p = .048, partial η(2) = .12) and an increase in sleep-related attentional bias (p = .032, d = 0.51) following the manipulation. However, changes in sleep and attentional bias were not maintained. Vulnerability to stress did not significantly account for any change in attentional bias, arousal, or sleep. These findings challenge current conceptualizations of the development of insomnia, yet also supporting the notion that good sleep is a default state that protects individuals from sleep disturbance.
Nistor, Katalin; Nistor, Anikó; Ádám, Szilvia; Szabó, Anita; Konkolÿ Thege, Barna; Stauder, Adrienne
2015-03-01
Research has shown that psychosocial stress acts as a risk factor for mental disorders. The present study aims at processing the preliminary results of the Hungarian Survey of Work Stress, concerning the relationship between depressive symptoms and work stress. Cross-sectional survey among Hungarian workers was carried out (n = 1058, 27.5% man, 72.5% woman, age 37.2 years, SD = 11 years). Psychosocial factors were measured using the COPSOQ II questionnaire, while BDI-9 was used for the assessment of depressive symptoms. Statistical analysis was carried out applying Spearman's correlation and logistic regression. A quarter of the workers reported moderate or severe symptoms of depression (BDI≥19). The study confirmed the association between depressive symptoms and work-family conflict (OR = 2.21, CI: 1.82-2.68), possibilities for development (OR = 0.76, CI: 0.59-0.97) meaning of work (OR = 0.69, CI: 0.59-0.89) and commitment (OR = 0.60, CI: 0.47-0.78). The results point toward the need of such organizational measures that allow for the reduction of psychosocial stress.
A preliminary study on identification of Thai rice samples by INAA and statistical analysis
NASA Astrophysics Data System (ADS)
Kongsri, S.; Kukusamude, C.
2017-09-01
This study aims to investigate the elemental compositions in 93 Thai rice samples using instrumental neutron activation analysis (INAA) and to identify rice according to their types and rice cultivars using statistical analysis. As, Mg, Cl, Al, Br, Mn, K, Rb and Zn in Thai jasmine rice and Sung Yod rice samples were successfully determined by INAA. The accuracy and precision of the INAA method were verified by SRM 1568a Rice Flour. All elements were found to be in a good agreement with the certified values. The precisions in term of %RSD were lower than 7%. The LODs were obtained in range of 0.01 to 29 mg kg-1. The concentration of 9 elements distributed in Thai rice samples was evaluated and used as chemical indicators to identify the type of rice samples. The result found that Mg, Cl, As, Br, Mn, K, Rb, and Zn concentrations in Thai jasmine rice samples are significantly different but there was no evidence that Al is significantly different from concentration in Sung Yod rice samples at 95% confidence interval. Our results may provide preliminary information for discrimination of rice samples and may be useful database of Thai rice.
Kazakis, Nikolaos A; Tsirliganis, Nestor C; Kitis, George
2015-11-01
Drug sterilization with ionizing radiation is a well-established technology, which is constantly extending to several products due to its numerous advantages, since it allows the heat-free sterilization of heat-sensitive pharmaceutical preparations. In a previous study, the possibility to identify irradiated solid-state drugs by means of OSL and TL was examined with very promising findings. In the same respect, the present work aims, for the first time to the authors' best knowledge, to explore whether TL can be employed as a method for post-sterilization dosimetry on commercial liquid-state drugs, by studying the properties of their glass containers. Two different types of glass containers (bottle and ampoule) of two widely used liquid drugs, i.e., Hexalen® and Voltaren®, are used for this purpose. Both glass containers exhibit a linear TL dose response for doses up to 6kGy with a stable behavior through time, while no significant sensitization of the main peaks is observed. Thus, preliminary findings are very promising towards the post-sterilization dosimetry of liquid drugs and the use of the containers of commercial liquid drugs for normal and/or accidental dosimetry. Copyright © 2015 Elsevier Ltd. All rights reserved.
Kim, Kyung Woo; Lim, Ho Chan; Park, Jae Hee; Park, Sang Gyu; Park, Ye Jin; Cho, Hm Hak
2018-06-01
Organizations are pursing complex and diverse aims to generate higher profits. Many workers experience high work intensity such as workload and work pressure in this organizational environment. Especially, psychological burden is a commonly used term in workplace of Republic of Korea. This study focused on defining the psychological burden from the perspective of occupational safety and health and tried to develop a scale for psychological burden. The 48 preliminary questionnaire items for psychological burden were prepared by a focus group interview with 16 workers through the Copenhagen Psychosocial Questionnaire II and Mindful Awareness Attention Scale. The preliminary items were surveyed with 572 workers, and exploratory factor analysis, confirmatory factor analysis, and correlation analysis were conducted for a new scale. As a result of the exploratory factor analysis, five factors were extracted: organizational activity, human error, safety and health workload, work attitude, and negative self-management. These factors had significant correlations and reliability, and the stability of the model for validity was confirmed using confirmatory factor analysis. The developed scale for psychological burden can measure workers' psychological burden in relation to safety and health. Despite some limitations, this study has applicability in the workplace, given the relatively small-sized questionnaire.
Emotion Understanding in Clinically Anxious Children: A Preliminary Investigation
Bender, Patrick K.; Pons, Francisco; Harris, Paul L.; Esbjørn, Barbara H.; Reinholdt-Dunne, Marie L.
2015-01-01
Children’s understanding of the nature, origins and consequences of emotions has been intensively investigated over the last 30–40 years. However, few empirical studies have looked at the relation between emotion understanding and anxiety in children and their results are mixed. The aim of the present study was to perform a preliminary investigation of the relationships between emotion understanding, anxiety, emotion dysregulation, and attachment security in clinically anxious children. A sample of 16 clinically anxious children (age 8–12, eight girls/boys) was assessed for emotion understanding (Test of Emotion Comprehension), anxiety (Screening for Child Anxiety Related Emotional Disorders-Revised and Anxiety Disorder Interview Schedule), emotion dysregulation (Difficulties in Emotion Regulation Scale) and attachment security (Security Scale). Children who reported more overall anxiety also reported greater difficulties in regulating their emotions, and were less securely attached to their parents. The results also showed that more specific symptoms of anxiety (i.e., OCD and PTSD) correlated not only with emotion dysregulation and attachment insecurity but also with emotion understanding. Finally, there were interrelations among emotion understanding, attachment security, and emotion dysregulation. The present results provide the first comprehensive evidence for a socio-emotional framework and its relevance to childhood anxiety. PMID:26733909
Preliminary investigation tests of novel antifungal topical aerosol
Kapadia, Monali M.; Solanki, S. T.; Parmar, V.; Thosar, M. M.; Pancholi, S. S.
2012-01-01
Spray formulation can minimize pain and irritation experience during the application of conventional dosage forms. Econazole Nitrate is an active ingredient of the aerosol concentrate to be used for twice-daily application because of its long durability in the superficial layers of the fungal infected skin. The aim of this study is preliminary investigation of Econazole Nitrate spray by varying the concentrations of different constituents of the spray. The ratios of Propylene glycol (PG) and isopropyl myristate (IPM) were selected as independent variables in 22 full factorial designs, keeping the concentration of solvent, co-solvent and propellant LPG constant. Aerosol also contained Ethanol as solvent and Isopropyl alcohol as co-solvent. All ingredients of the aerosol were packaged in an aluminum container fitted with continuous-spray valves. Physical properties evaluated for the Econazole Nitrate spray included delivery rate, delivery amount, pressure, minimum fill, leakage, flammability, spray patterns, particle image and plume angle. Glass containers were used to study incompatibility between concentrate and propellant due to the ease of visible inspection. Isopropyl myristate at lower concentrate showed turbidity, while at high concentration it met the requirements for aerosol and produced Econazole Nitrate spray with expected characteristics. PMID:23066214
de Souza Aranha E Silva, Renata Almeida; Baltieri, Danilo Antonio
2016-01-01
Although zoophilic blogs and websites attract the attention of zoophiles and others who are curious about this sexual activity, the motivations for consuming this type of pornography are not clear. This study aimed to confirm the factorial validity of the Pornography Consumption Inventory in an online sample of men with sexual interest in animals, and to construct an association model between motivations for pornography consumption and the following psychological variables: depression, sexual impulsiveness, and strength of sexual interest in animals. In this cross-sectional study, we located a website that catered to a network of people with a sexual interest in animals. Subsequently, a questionnaire was made available online to members of this network. Results support the 4-factor model of the Pornography Consumption Inventory. Depression and strength of sexual interest in animals were negatively and positively correlated with the sexual curiosity factor, respectively. Sexual impulsiveness was positively associated with the emotional avoidance, excitement seeking, and sexual pleasure factors. Depression and sexual impulsiveness were positively correlated. Psychological factors can differently motivate the consumption of pornography among men who visit zoophilic blogs and websites. With these preliminary data, we can identify some characteristics of this population.
Teaching: An Interplay of Aims, Constraints, Conflicts, and Compromises.
ERIC Educational Resources Information Center
Oukada, Larbi
2000-01-01
Discusses preliminary observations on the notion of "tension" as an inevitable agent of developmental change and to show that at the source of tension are constraints of epistemological, semiotic, learning, and environmental nature. Focuses on four constraints that exert inevitable and pedagogically fruitful tension on classroom teaching.…
NASA Astrophysics Data System (ADS)
Mari, N.; Riches, A. J. V.; Hallis, L. J.; Lee, M. R.
2017-07-01
This project, for the first time, aims to integrate nakhlite Os-isotope compositions and HSE abundance data with S-isotope compositions for sample fractions for which textural information is constrained prior to destructive analyses.
Peer Observation of Teaching: Enhancing Academic Engagement for New Participants
ERIC Educational Resources Information Center
Carroll, Conor; O'Loughlin, Deirdre
2014-01-01
This research aims to uncover key motivations, barriers and outcomes associated with first-time users of peer observation of teaching within an Irish higher level academic context. Following preliminary research, a peer observation process was piloted on five self-selected peer observation faculty pairs involving peer observation training and…
ERIC Educational Resources Information Center
Yeung, Olivia; Law, Sam-Po; Yau, Monna
2009-01-01
Background: While various treatment approaches have been shown to be effective in remediating word-finding difficulties in aphasic individuals, interest has recently been directed at the role of executive functions in affecting treatment outcomes. Aims: To examine the existence of a possible relationship between treatment generalization and…
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-08
... biology. The Assistant Regional Administrator has also made a preliminary determination that the... investigating the reproductive biology of dogfish along the U.S. Atlantic coast. UNE will investigate previously observed regional anomalies in dogfish reproductive biology. Investigators from UNE aim to update...
Development and Initial Validation of a Rock Climbing Craving Questionnaire (RCCQ)
Roderique-Davies, Gareth; Heirene, Robert M.; Mellalieu, Stephen; Shearer, David A.
2018-01-01
Conceptual similarities have been identified between experiences of extreme sports athletes and those with drug and behavioral addictions. Evidence suggests rock climbers experience craving and other withdrawal-like states when abstinent from their sport. However, no studies have attempted to quantitatively measure the craving experienced by participants of any extreme sports. Such a measure could allow a greater understanding of the craving experienced by extreme sports athletes and a comparison of these across sports (e.g., surfing) and activities (e.g., drug-use). Therefore, using validated craving measures as a template, the aim of the two studies outlined here was to design and preliminarily validate a subjective multidimensional inventory that could be used to measure craving in the sports of rock-climbing and mountaineering (“RCCQ”). The aim of the first study was to investigate the factor structure of a preliminary measure of craving. Climbers (n = 407) completed the RCCQ. A 3-factor model explained 53.65% of the total variance in item scores. All three factors comprised five items each, which were conceptually labeled as “urge to climb” “negative reinforcement” and “positive reinforcement.” The aim of the second study was to validate the 15-item 3-factor RCCQ resulting from Study 1 using confirmatory factor analysis (CFA). Climbers (n = 254) completed the questionnaire under a climbing-related cue condition or a cue-neutral condition. CFA revealed a good model fit and that all individual parameter estimates were significant and standard errors were within reasonable limits once item 13 was removed from Factor 1. Study 1 supports the multi-dimensional nature of rock climbing craving and shows parallels with substance-related craving in reflecting intention and positive (desire) and negative (withdrawal) reinforcement. Study 2 confirms this factor structure and gives initial validation to the measure with evidence that these factors are sensitive to cue exposure. Given the preliminary nature of the data, any practical implications are tentative. However, if as shown here, craving for climbing (and potentially other extreme sports) is similar to that experienced by drug-users and addicts, there is the potential that climbing and other extreme sports could be used as a replacement therapy for drug users. PMID:29520248
Bruno, Antonio; Pandolfo, Gianluca; Crucitti, Manuela; Lorusso, Simona; Zoccali, Rocco Antonio; Muscatello, Maria Rosaria Anna
This was the first 12-week, open-label, uncontrolled trial aimed at exploring the efficacy of acetyl-L-carnitine (ALC) add-on pharmacotherapy on clinical symptoms and cognitive functioning in 15 schizophrenia patients with suboptimal clinical response despite receiving clozapine (CLZ) monotherapy at the highest tolerated dosage. After clinical (Positive and Negative Symptoms Scale [PANSS]) and neuropsychological (Wisconsin Card Sorting Test, Stroop Color-Word Test, Verbal Fluency Test) assessments, patients received 1 g/d of ALC for 12 weeks. A final sample of 9 subjects completed the study. Acetyl-L-carnitine augmentation of CLZ significantly reduced only PANSS domains "positive" (P = 0.049); at end point, only 2 subjects (22.2% of the completers) reached a minimal improvement (25% reduction in PANSS total score). No significant differences emerged in cognitive performances at the end of the study; effect sizes were small in each explored cognitive dimension. The findings provide preliminary evidence that ALC added to ongoing CLZ treatment appeared to be ineffective to improve symptoms in schizophrenia patients who have failed to respond sufficiently to CLZ. Further trials with adequately powered methodology are needed to identify which augmentation strategies are more effective in schizophrenia patients showing a suboptimal response to CLZ.
Tailored prevention of inpatient falls: development and usability testing of the fall TIPS toolkit.
Zuyev, Lyubov; Benoit, Angela N; Chang, Frank Y; Dykes, Patricia C
2011-02-01
Patient falls and fall-related injuries are serious problems in hospitals. The Fall TIPS application aims to prevent patient falls by translating routine nursing fall risk assessment into a decision support intervention that communicates fall risk status and creates a tailored evidence-based plan of care that is accessible to the care team, patients, and family members. In our design and implementation of the Fall TIPS toolkit, we used the Spiral Software Development Life Cycle model. Three output tools available to be generated from the toolkit are bed poster, plan of care, and patient education handout. A preliminary design of the application was based on initial requirements defined by project leaders and informed by focus groups with end users. Preliminary design partially simulated the paper version of the Morse Fall Scale currently used in hospitals involved in the research study. Strengths and weaknesses of the first prototype were identified by heuristic evaluation. Usability testing was performed at sites where research study is implemented. Suggestions mentioned by end users participating in usability studies were either directly incorporated into the toolkit and output tools, were slightly modified, or will be addressed during training. The next step is implementation of the fall prevention toolkit on the pilot testing units.
Bohbot, Albert
2010-01-01
Preliminary results were measured by electromyography monitoring (electromyoscan) on three subjects suffering from spinal cord injury and who underwent a double therapy. The aim of this study was to evaluate regained voluntary activity below the injury in subjects who received a double therapy: 1) an olfactory ensheathing glia (OEG) transplantation using procedures developed by Dr. Hongyun Huang at the Xishan Hospital and Rehabilitation Centre, Beijing, China, and 2) LASERPONCTURE developed by Albert Bohbot, Laboratoire de Recherches sur le LASERPONCTURE, La Chapelle Montlinard, France. Materials uses were the LASERPONCTURE device developed by Albert Bohbot; the PROCOMP5 equipment with softwares BIOGRAPH INFINITI 5 and REHAB SUITE; the sensors MYOSCAN-PRO EMG (SA9401M-50) to record muscle activity, and FLEX/PRO-SA9309M to record skin conductance were fixed on the skin. An infrared laser, whose frequencies and power settings cannot be disclosed due to its proprietary nature, was applied after an OEG injection performed according to Dr. Hongyun Huang's procedures. Three cases, two males and one female, were selected for this study. Presentation and comments of the graphs recordings of voluntary muscle activity below the injury are provided. This preliminary study suggests that the double therapy restores some voluntary muscle activity as measured by electromyography monitoring.
Preliminary seismic studies at Ceboruco Volcano
NASA Astrophysics Data System (ADS)
Escudero, C. R.; Nunez-Cornu, F. J.; Ochoa, J.; Robles, F. J.
2012-12-01
Many societies and their economies endure the disastrous consequences of destructive volcanic eruptions. The Ceboruco stratovolcano is located at the west of the Mexican volcanic belt at 21.125o north, 76 km from the pacific coast and 2,280 meters above sea level. It has an eruptive recurrence of 200 years and its last activity was at 1875. This natural hazard could affect more than eight communities and important highways. Scientific knowledge constitutes the only way to avoid or at least to mitigate the negative effects of an eventual eruptive event, accordingly the main objective of this project is monitor and analyze the potential destructive effects of the Ceboruco volcano. Seismic studies began at 2003 with the deployment of one MARSlite station equipped LE3d (1Hz) sensor. Station that works until 2009 and allow us to identify and characterize the seismic activity associated to the volcano;. Since March 2012 we installed four seismic stations, each includes a digital acquisition system TAURUS of Nanometrix and a Lennartz 3D lite seismometer. Batteries are change and data collected monthly. We use the data to establish the average seismic activity rate; we also aim to corroborate previous studies that showed four families of seismic events; and to localize and make preliminary evaluations of the events.
NASA Astrophysics Data System (ADS)
Lavigne, T.; Liu, C.
2017-12-01
Previous studies focusing on the comparison of the measured electric field to the physical properties of global electrified clouds have been conducted almost exclusively in the Southern Hemisphere. The One-Year Electric Field Study-North Slope of Alaska (OYES-NSA) aims to establish a long-running collection of this valuable electric field data in the Northern Hemisphere. Presented here is the six-month preliminary data and results of the OYES-NSA Atmospheric Radiation Mission (ARM) field campaign. The local electric field measured in Barrow, Alaska using two CS110 reciprocating shutter field meters, has been compared to simultaneous measurements from the ARM Ka-Band zenith radar, to better understand the influence and contribution of different types of clouds on the local electric field. The fair-weather electric field measured in Barrow has also been analyzed and compared to the climatology of electric field at Vostok Station, Antarctica. The combination of the electric field dataset in the Northern Hemisphere, alongside the local Ka cloud radar, global Precipitation Feature (PF) database, and quasi-global lightning activity (55oN-55oS), allows for advances in the physical understanding of the local electric field, as well as the Global Electric Circuit (GEC).
Markova, Nadezhda V; Batovska, Daniela I; Kozuharova, Ekaterina K; Enchev, Venelin G
2015-01-01
The parent of xGraptoveria, Graptopetalum paraguayense, is used in Chinese folk medicine for alleviating hepatic disorders, detumescence and detoxication, lowering of blood pressure, inhibition of cancer cells, exerting diuretic effects, relieving pain and infections. No data are available regarding its anti-conjunctivitis effect. The aim of this preliminary study is to test the anti-conjunctivitis properties of xGraptoveria (Crassulaceae) and to identify its bioactive constituents. Fresh watery juice of leaves of xGraptoveria was extracted with n-butanol and the extract was analyzed using gas chromatography-mass spectrometry (GC/MS). The ethnobotanical appraisal of the anti-conjunctivitis properties of xGraptoveria was based on 11 interviews about the symptoms against which this plant demonstrated positive effect. Fresh juice of xGraptoveria leaves applied directly to the irritated eye 2 times per day cured conjunctivitis in all reported cases. The main groups of organic compounds identified by GC/MS analysis in the fresh extracted leaf juice of xGraptoveria were: Alkylamines, hydroxycarboxylic acids, aliphatic and aromatic carboxylic acids, amino acids, alcohols, aromatic and aliphatic hydrocarbons. In this preliminary study, it is suggested that xGraptoveria exerts anti-conjunctivitis activity, through synergistic effect of different chemical compounds, most probably alkylamines and mainly hydroxycarboxylic, aliphatic, and aromatic carboxylic acids.
A preliminary design study for a cosmic X-ray spectrometer
NASA Technical Reports Server (NTRS)
1972-01-01
The results are described of theoretical and experimental investigations aimed at the development of a curved crystal cosmic X-ray spectrometer to be used at the focal plane of the large orbiting X-ray telescope on the third High Energy Astronomical Observatory. The effort was concentrated on the development of spectrometer concepts and their evaluation by theoretical analysis, computer simulation, and laboratory testing with breadboard arrangements of crystals and detectors. In addition, a computer-controlled facility for precision testing and evaluation of crystals in air and vacuum was constructed. A summary of research objectives and results is included.
Non-Invasive Evaluation of Corneal Abnormalities Using Static and Dynamic Light Scattering
NASA Technical Reports Server (NTRS)
Ansari, Rafat R.; Misra, Anup K.; Leung, Alfred B.; King, James F.; Datiles, Manuel B., III
2002-01-01
A preliminary study of corneal abnormalities in intact bovine eyes is presented. Twenty-one eyes were treated with chemicals, cotton swabs, and radial and photo-refractive surgeries. Dynamic and static light scattering was performed as a function of the penetration depth into the corneal tissue. Topographical maps of corneal refractive power from untreated and treated corneas were also obtained using videokeratoscopy and results compared. The ultimate aim is to develop the technique of dynamic light scattering (DLS) for clinical applications in early evaluation of corneal complications after laser-assisted in situ keratomileusis (LASIK) surgeries and other corneal abnormalities.
Pressure vessel burst test program - Initial program paper
NASA Technical Reports Server (NTRS)
Cain, Maurice R.; Sharp, Douglas E.; Coleman, Michael D.; Webb, Bobby L.
1990-01-01
The current status of a pressure vessel burst test program, aimed at the study of the blast waves and fragmentation characteristics of ruptured gas-filled pressure vessels, is reported. The program includes a series of test plans, each involving multiple bursts with burst pressures ranging to 7500 psig. The discussion covers the identification of concerns and hazards, application of the data generated, and a brief review of the current methods for assessing vessel safety and burst parameters. Attention is also given to pretest activities, including completed vessel and facility/instrumentation preparation and results of completed preliminary burst tests.
Noninvasive evaluation of corneal abnormalities using static and dynamic light scattering
NASA Astrophysics Data System (ADS)
Ansari, Rafat R.; Misra, Anup K.; Leung, Alfred B.; King, James F.; Datiles, Manuel B., III
2002-06-01
A preliminary study of corneal abnormalities in intact bovine eyes is presented. Twenty-one eyes were treated with chemicals, cotton swabs, and radial and photo-refractive surgeries. Dynamic and static light scattering was performed as a function of the penetration depth into the corneal tissue. Topographical maps of corneal refractive power from untreated and treated corneas were also obtained using videokeratoscopy and results compared. The ultimate aim is to develop the technique of dynamic light scattering (DLS) for clinical applications in early evaluation of corneal complications after laser-assisted in situ keratomileusis (LASIK) surgeries and other corneal abnormalities.
Biofeedback and dance performance: a preliminary investigation.
Raymond, Joshua; Sajid, Imran; Parkinson, Lesley A; Gruzelier, John H
2005-03-01
Alpha-theta neurofeedback has been shown to produce professionally significant performance improvements in music students. The present study aimed to extend this work to a different performing art and compare alpha-theta neurofeedback with another form of biofeedback: heart rate variability (HRV) biofeedback. Twenty-four ballroom and Latin dancers were randomly allocated to three groups, one receiving neurofeedback, one HRV biofeedback and one no intervention. Dance was assessed before and after training. Performance improvements were found in the biofeedback groups but not in the control group. Neurofeedback and HRV biofeedback benefited performance in different ways. A replication with larger sample sizes is required.
Karatzias, Thanos; Cloitre, Marylene; Maercker, Andreas; Kazlauskas, Evaldas; Shevlin, Mark; Hyland, Philip; Bisson, Jonathan I.; Roberts, Neil P.; Brewin, Chris R.
2017-01-01
ABSTRACT The 11th revision to the World Health Organization’s International Classification of Diseases (ICD-11) proposes two distinct sibling conditions: Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD). In this paper, we aim to provide an update on the latest research regarding the conceptual structure and measurement of PTSD and CPTSD using the International Trauma Questionnaire (ITQ) as per ICD-11 proposals in the USA, UK, Germany and Lithuania. Preliminary findings suggest that CPTSD is common in clinical and population samples, although there may be variations across countries in prevalence rates. In clinical samples, preliminary evidence suggests that CPTSD is a more commonly observed condition than PTSD. Preliminary evidence also suggests that the ITQ scores are reliable and valid and can adequately distinguish between PTSD and CPTSD. Further cross-cultural work is proposed to explore differences in PTSD and CPTSD across different countries with regard to prevalence, incidence, and predictors of PTSD and CPTSD. PMID:29372010
Boutopoulou, Barbara; Clarke, Andrew; Christothanopoulou, Ioanna; Douros, Konstantinos; Tsirouda, Maria; Papaevangelou, Vasiliki
2016-05-09
Theme: Accreditation and quality improvement. Child Friendly Healthcare Initiative (CFHI) aims to improve quality of experience and health care given to children and families by improving realisation of children's rights and reducing unnecessary fear, anxiety and suffering during and because of health care. To present results of preliminary CFH assessment. Implementation was initiated in a paediatric department of a University Hospital in Athens, Greece, consisting of a 37-bed ward, Outpatient Clinic and Emergency Department. For the preliminary assessment of the CFHI tool No1, which is for parents-caregiverschildren and health workers, this was translated into Greek. 112 parents-caregivers and six children were interviewed by an independent interviewer. In total, 24 health workers - 5 paediatricians, 11 residents and 8 nurses - responded to the CFHI tool No 1. Issues highlighted were mostly about CFH Standard 3 and Standard 7. Suggestions for improvement in all Standards were suggested. Preliminary assessment revealed the quality of care needs improvement. The next step is the training health workers, planning and making improvements.
Karatzias, Thanos; Cloitre, Marylene; Maercker, Andreas; Kazlauskas, Evaldas; Shevlin, Mark; Hyland, Philip; Bisson, Jonathan I; Roberts, Neil P; Brewin, Chris R
2017-01-01
The 11th revision to the World Health Organization's International Classification of Diseases (ICD-11) proposes two distinct sibling conditions: Posttraumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD). In this paper, we aim to provide an update on the latest research regarding the conceptual structure and measurement of PTSD and CPTSD using the International Trauma Questionnaire (ITQ) as per ICD-11 proposals in the USA, UK, Germany and Lithuania. Preliminary findings suggest that CPTSD is common in clinical and population samples, although there may be variations across countries in prevalence rates. In clinical samples, preliminary evidence suggests that CPTSD is a more commonly observed condition than PTSD. Preliminary evidence also suggests that the ITQ scores are reliable and valid and can adequately distinguish between PTSD and CPTSD. Further cross-cultural work is proposed to explore differences in PTSD and CPTSD across different countries with regard to prevalence, incidence, and predictors of PTSD and CPTSD.
Oliveira, Camila R; Lopes Filho, Brandel José P; Sugarman, Michael A; Esteves, Cristiane S; Lima, Margarida Maria B M P; Moret-Tatay, Carmen; Irigaray, Tatiana Q; Argimon, Irani Iracema L
2016-12-13
Cognitive assessment with virtual reality (VR) may have superior ecological validity for older adults compared to traditional pencil-and-paper cognitive assessment. However, few studies have reported the development of VR tasks. The aim of this study was to present the development, feasibility, content validity, and preliminary evidence of construct validity of an ecological task of cognitive assessment for older adults in VR (ECO-VR). The tasks were prepared based on theoretical and clinical backgrounds. We had 29 non-expert judges identify virtual visual stimuli and three-dimensional scenarios, and five expert judges assisted with content analysis and developing instructions. Finally, six older persons participated in three pilot studies and thirty older persons participated in the preliminary study to identify construct validity evidence. Data were analyzed by descriptive statistics and partial correlation. Target stimuli and three-dimensional scenarios were judged adequate and the content analysis demonstrated that ECO-VR evaluates temporo-spatial orientation, memory, language and executive functioning. We made significant changes to the instructions after the pilot studies to increase comprehensibility and reduce the completion time. The total score of ECO-VR was positively correlated mainly with performance in executive function (r = .172, p < .05) and memory tests (r = .488, p ≤ .01). The ECO-VR demonstrated feasibility for cognitive assessment in older adults, as well as content and construct validity evidences.
Wolthers, Ole D; Mersmann, Sabine; Dissanayake, Sanjeeva
2018-04-01
For more than a decade, urinary free cortisol corrected for creatinine (OUFCC) has been used to assess the systemic bioactivity of inhaled corticosteroids in children with asthma. Paediatric normative ranges, however, have not been established. The aim of the present study was to define a preliminary range for OUFCC in Tanner stage 1 children. A post hoc analysis was performed of 26 Tanner stage one children (aged 5-11 years) with mild asthma only requiring prn (pro re nata) treatment with short-acting β 2 -agonists, who participated in a 3-way cross-over knemometry study. The study comprised a run-in, two washout periods and three treatment periods (2 weeks each). Urine was collected at the end of each period. A normative range was derived using the 95% prediction interval for the geometric mean OUFCC, calculated from run-in and washout periods. Twenty-six children contributed 41 OUFCC values. The geometric mean OUFCC was 9.0 nmol/mmol (95% PI: 3.6, 22.7 nmol/mmol). The OUFCC preliminary normative range was 3.6 to 22.7 nmol/mmol in Tanner stage one children. A larger study in healthy children is warranted to confirm these findings and to assess potential differences in OUFCC across developmental stages and age groups, and by gender and race. 2013-004719-32, CLINICALTRIALS. NCT02063139.
Lim, Yen Ying; Villemagne, Victor L.; Laws, Simon M.; Ames, David; Pietrzak, Robert H.; Ellis, Kathryn A.; Harrington, Karra; Bourgeat, Pierrick; Bush, Ashley I.; Martins, Ralph N.; Masters, Colin L.; Rowe, Christopher C.; Maruff, Paul
2014-01-01
Objective Cross-sectional genetic association studies have reported equivocal results on the relationship between the brain-derived neurotrophic factor (BDNF) Val66Met and risk of Alzheimer’s disease (AD). As AD is a neurodegenerative disease, genetic influences may become clearer from prospective study. We aimed to determine whether BDNF Val66Met polymorphism influences changes in memory performance, hippocampal volume, and Aβ accumulation in adults with amnestic mild cognitive impairment (aMCI) and high Aβ. Methods Thirty-four adults with aMCI were recruited from the Australian, Imaging, Biomarkers and Lifestyle (AIBL) Study. Participants underwent PiB-PET and structural MRI neuroimaging, neuropsychological assessments and BDNF genotyping at baseline, 18 month, and 36 month assessments. Results In individuals with aMCI and high Aβ, Met carriers showed significant and large decline in episodic memory (d = 0.90, p = .020) and hippocampal volume (d = 0.98, p = .035). BDNF Val66Met was unrelated to the rate of Aβ accumulation (d = −0.35, p = .401). Conclusions Although preliminary due to the small sample size, results of this study suggest that high Aβ levels and Met carriage may be useful prognostic markers of accelerated decline in episodic memory, and reductions in hippocampal volume in individuals in the prodromal or MCI stage of AD. PMID:24475133
Williams, J.M.G.; Alatiq, Y.; Crane, C.; Barnhofer, T.; Fennell, M.J.V.; Duggan, D.S.; Hepburn, S.; Goodwin, G.M.
2008-01-01
Background Bipolar disorder is highly recurrent and rates of comorbidity are high. Studies have pointed to anxiety comorbidity as one factor associated with risk of suicide attempts and poor overall outcome. This study aimed to explore the feasibility and potential benefits of a new psychological treatment (Mindfulness-based Cognitive Therapy: MBCT) for people with bipolar disorder focusing on between-episode anxiety and depressive symptoms. Methods The study used data from a pilot randomized trial of MBCT for people with bipolar disorder in remission, focusing on between-episode anxiety and depressive symptoms. Immediate effects of MBCT versus waitlist on levels of anxiety and depression were compared between unipolar and bipolar participants. Results The results suggest that MBCT led to improved immediate outcomes in terms of anxiety which were specific to the bipolar group. Both bipolar and unipolar participants allocated to MBCT showed reductions in residual depressive symptoms relative to those allocated to the waitlist condition. Limitations Analyses were based on a small sample, limiting power. Additionally the study recruited participants with suicidal ideation or behaviour so the findings cannot immediately be generalized to individuals without these symptoms. Conclusions The study, although preliminary, suggests an immediate effect of MBCT on anxiety and depressive symptoms among bipolar participants with suicidal ideation or behaviour, and indicates that further research into the use of MBCT with bipolar patients may be warranted. PMID:17884176
NASA Astrophysics Data System (ADS)
Marchesini, Barbara; Garofalo, Paolo S.; Viola, Giulio; Mattila, Jussi; Menegon, Luca
2017-04-01
Brittle faults are well known as preferential conduits for localised fluid flow in crystalline rocks. Their study can thus reveal fundamental details of the physical-chemical properties of the flowing fluid phase and of the mutual feedbacks between mechanical properties of faults and fluids. Crustal deformation at the brittle-ductile transition may occur by a combination of competing brittle fracturing and viscous flow processes, with short-lived variations in fluid pressure as a viable mechanism to produce this cyclicity switch. Therefore, a detailed study of the fluid phases potentially present in faults can help to better constrain the dynamic evolution of crustal strength within the seismogenic zone, as a function of varying fluid phase characteristics. With the aim to 1) better understand the complexity of brittle-ductile cyclicity under upper to mid-crustal conditions and 2) define the physical and chemical features of the involved fluid phase, we present the preliminary results of a recently launched (micro)structural and geochemical project. We study deformed quartz veins associated with brittle-ductile deformation zones on Olkiluoto Island, chosen as the site for the Finnish deep repository for spent nuclear fuel excavated in the Paleoproterozoic crust of southwestern Finland. The presented results stem from the study of brittle fault zone BFZ300, which is a mixed brittle and ductile deformation zone characterized by complex kinematics and associated with multiple generations of quartz veins, and which serves as a pertinent example of the mechanisms of fluid flow-deformation feedbacks during brittle-ductile cyclicity in nature. A kinematic and dynamic mesostructural study is being integrated with the detailed analysis of petrographic thin sections from the fault core and its immediate surroundings with the aim to reconstruct the mechanical deformation history along the entire deformation zone. Based on the observed microstructures, it was possible to recognize three distinct episodes of ductile deformation alternating with at least three brittle episodes. Preliminary fluid inclusion data show that, during crystallization and brittle-viscous deformation, quartz crystals hosted homogeneous and heterogeneous (boiling) aqueous fluids with a large salinity (11.7-0 wt% NaCleq) and Thtot (410-200 °C) range. Boiling occurred at 200-260 °C. Variations of fluid temperature and density (hence, viscosity) may thus have induced localized cyclic switches between brittle and ductile deformation in quartz, with implications on the bulk regional crustal strength. Preliminary EBSD analysis also supports the hypothesis of cyclic switches between brittle and viscous deformation.
An educational board game for learning and teaching burn care: A preliminary evaluation.
Whittam, Alexander M; Chow, Whitney
2017-01-01
Timely and effective assessment, resuscitation and transfer of patients with severe burns has been demonstrated to improve outcome. A dedicated one-day course exists to equip all frontline emergency healthcare workers with the necessary knowledge and skills to manage severe burn injuries. More recently, a board game has been developed which aims to act as a learning and practice development tool for those managing burn injuries. We present the findings of our preliminary evaluation of this game. We played this game with a multidisciplinary group of staff including doctors, nurses and therapists. A proportion of these participants had previously completed the Emergency Management of Severe Burns (EMSB) course. We obtained subjective results from a questionnaire, using both Likert-type ratings and open-ended questions. The styling of the game and ease of instructions was rated from 'average' to 'excellent'. The relevance of questions was rated from 'good' to 'excellent'. The usefulness of the game to increase knowledge and stimulate discussion was rated between 'good' and 'excellent'. All participants stated that they would recommend the game to other healthcare professionals. This is the only burns and plastic surgery-related educational game in the literature. Educational games adhere to principles of adult learning but there is insufficient evidence in the literature to either confirm or refute their utility. Our preliminary evaluation of this game has shown that it achieves its main aims, namely to increase knowledge in burn care and to stimulate discussion. Further work is required to assess the board game.
Development of Souvenir Production Transaction Processing System
NASA Astrophysics Data System (ADS)
Rumambi, H.; Kaparang, R.; Lintong, J.
2018-01-01
This research aims to design a souvenir production transaction processing system for the craftsmen in North Sulawesi. The craftsmen make very simple recordings about souvenir production transactions and use documents that are not in accordance with the generally accepted accounting practices. This research uses qualitative method. The data is collected through interviews, observations, documents and literatures studies. The research stages are conducted in preliminary studies, data collection, data analyzed and system design. The design of system is built from chart of account, accounting cycle and documents as input and get processed in accounting recording. The outputs are financial statements. The system design provides benefits for the craftsmen in assessing the financial performance and getting financing from bank.
Guidi, Enrica; Lupi, Silvia; Vicentini, Chiara Beatrice; Manfredini, Stefano; Altieri, Lorenzo; Scivales, Sonia; Contini, Carlo
2012-12-01
The authors carried out an observational study for the years 1867-1874 on the morbidity of children from Ferrara suffering from scrofula, sent to marine hospices for sea bathing treatment. A total of 490 cases (250 F, 240 M) were studied in relation to the following variables: age, sex, forms of scrofula, years and outcome. In particular, the present work describes the preliminary organizational steps planned to allow the seaside stay, the clinical features and the outcomes. Dissemination of information to the public and to benefactors had the specific aim to strengthen these benefits for those children affected by the sad and serious consequences of scrofula.
NASA Astrophysics Data System (ADS)
Bonivento, Walter M.
2018-02-01
This paper describes the basic ideas and the first simulation results of a new electro-magnetic calorimeter concept, named SplitCal, aimed at optimising the measurement of photon direction in fixed-target experiment configuration, with high photon detection efficiency. This calorimeter was designed for the invariant mass reconstruction of axion-like particles decaying into two photons in the mass range 200 MeV to 1 GeV for the proposed proton beam dump experiment SHiP at CERN. Preliminary results indicate that angular resolutions better than obtained by past experiments can be achieved with this design. An implementation of this concept with real technologies is under study.
[Efficacy analysis and theoretical study on Chinese herbal properties of Açaí (Euterpe oleracea)].
Zhang, Jian-jun; Chen, Shao-hong; Zhu, Ying-li; Wang, Chun; Wang, Jing-xia; Wang, Lin-yuan; Gao, Xue-min
2015-06-01
Açaí (Euterpe oleracea) emerged as a source of herb has a long history in South America, which was approved by the Ministry of Health used in China and it has been introduced planting in Guangdong and Taiwan. This article summarized applied history of Açaí and its present status in China. Did theoretical study on the Chinese herbal properties of Açaí based on the Chinese traditional philosophical culture to analysis the function and symptom preliminary, combining with used for medical recordation, chemical component, biological activity. It is aiming at establishing the theoretical foundation for the application under the guidance of TCM theory.
Ramírez-Mosqueda, Marco A; Iglesias-Andreu, Lourdes G; Sáenz, Luis; Córdova, Iván
2018-02-01
This work aimed to evaluate the embryogenic competence of different tissues from different stages (friable callus, bud-regenerating callus, and whole buds) of Vanilla planifolia , through the molecular detection of the somatic embryogenesis receptor-like kinase ( VpSERK ) and knotted-like homeobox ( VpKNOX1 ) genes. RNA was extracted with Trizol ® , cDNA was obtained, and the studied transcripts were amplified. Using non-specific primers, VpSERK and VpSTM gene expression was detected in the three stages evaluated. This study might contribute to providing an explanation for the recalcitrance of this Vanilla species to somatic embryogenesis.
Blaser, A Reintam; Starkopf, J; Kirsimägi, Ü; Deane, A M
2014-09-01
Clinicians and researchers frequently use the phrase 'feeding intolerance' (FI) as a descriptive term in enterally fed critically ill patients. We aimed to: (1) determine what is the most accepted definition of FI; (2) estimate the prevalence of FI; and (3) evaluate whether FI is associated with important outcomes. Systematic searches of peer-reviewed publications using PubMed, MEDLINE, and Web of Science were performed with studies reporting FI extracted. We identified 72 studies defining FI. In 33 studies, the definition was based on large gastric residual volumes (GRVs) together with other gastrointestinal symptoms, while 30 studies relied solely on large GRVs, six studies used inadequate delivery of enteral nutrition (EN) as a threshold, and three studies gastrointestinal symptoms without reference to GRV. The median volume used to define a 'large' GRV was 250 ml (ranges from 75 to 500 ml). The pooled proportion (n = 31 studies) of FI was 38.3% (95% CI 30.7-46.2). Five studies reported outcomes, all of them observed adverse outcome in FI patients. In three studies, respectively, FI was associated with increased mortality and ICU length-of-stay. In summary, FI is inconsistently defined but appears to occur frequently. There are preliminary data indicating that FI is associated with adverse outcomes. A standard definition of FI is required to determine the accuracy of these preliminary data. © 2014 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
Changes in Cerebral Cortical Thickness Related to Weight Loss Following Bariatric Surgery.
Bohon, Cara; Garcia, Luis C; Morton, John M
2018-06-06
Cerebral cortical thickness is associated with memory and intelligence test scores and serves as a measure for changes in cortical gray matter. Previous studies suggest reduced cortical thickness in patients with obesity. This study aimed to investigate changes in cortical thickness following bariatric surgery. Magnetic resonance imaging (MRI) data of five patients were analyzed preoperatively and 6 months postoperatively to assess changes in global measures of cortical thickness. No patients were lost to follow-up. This study provides preliminary evidence of brain change following surgery, suggests increases in cerebral cortical thickness in patients with greater excess weight loss, and indicates the need for further investigation using larger samples and correlation with neurocognitive measures, such as memory recall.
Wang, Yuzheng; Xu, Wei; Zhuang, Capella; Liu, Xinghua
2017-02-01
The aim of this study was to assess the relationship between trait mindfulness and mood and to examine whether the relationship is mediated by mind wandering. Eighty-two individuals ( M age = 24.27 years, SD = 5.64, 18 men, 22%) completed a series of measures including the Five-Facet Mindfulness Questionnaire, the Profile of Mood States Questionnaire, and Meditation Breath Attention Exercise. Results showed that the level of mindfulness was significantly correlated with positive and negative mood, and the association between mindfulness and negative mood was mediated by mind wandering. This study indicated the important role of mind wandering in the relation between mindfulness and negative mood. Limitations and future research directions are discussed.
Ando, Takanori; Maeda, Yoshinobu; Wada, Masahiro; Gonda, Tomoya
2011-01-01
The aim of this study was to establish a method for in vivo examination of the load-bearing ratio between mucosa and abutments beneath an overdenture. Two patients wearing a four tooth-supported or a four implant-supported overdenture were enrolled in this study. Recordings were performed with the metal framework only or with a metal framework and a denture base. The force value with the framework only was designated as 100%, and the tissue-supporting ratio (TSR) with the denture base was calculated. The TSR was approximately 30% to 40% in both subjects, regardless of the load. These data suggest that measurement of a TSR beneath an overdenture is feasible.
Anticariogenic activity and phytochemical studies of crude extract from some Indian plant leaves
Barad, Mahesh K.; Ishnava, Kalpesh B.; Chauhan, Jenabhai B.
2014-01-01
Aim: The aim was to screen the selected Indian plants for their antibacterial efficacy against four cariogenic bacteria Lactobacillus acidophilus (LA)(Microbial Type Culture Collection [MTCC]-*447), Lactobacillus casei (LC) (MTCC-1423), Streptococcus mutans (SMU) (MTCC-890) and Staphylococcus aureus (MTCC-96). To identify and characterize active principle present in these plants for the treatment of dental caries. Materials and Methods: The dried plant leaves materials are extracted by cold extraction using hexane, ethyl acetate, methanol, and distilled water. The solvents were evaporated, and the dried masses were suspended in dimethyl sulfoxide and used for anticariogenic activity by agar well diffusion method. Minimum inhibitory concentration (MIC) was evaluated by two-fold serial broth dilution method. Preliminary phytochemical analysis of effective extract was carried out by thin-layer chromatography (TLC) and bioautography. Results: Ethyl acetate and hexane extract of Eucalyptus globules was found most effective against L. acidophilus with MIC value 31 μg/ml and 62 μg/ml, respectively. Ethyl acetate extracts of Acacia nilotica and methanolic extract of E. globules also exhibited antibacterial activity against SMU and L. casei with MIC value of 50 μg/ml. Qualitative analysis of E. globules revealed the presence of alkaloids, terpenoids, phenolic compounds, and cardiac glycosides. The active principle responsible for the anticariogenic activity from E. globules were separated by TLC and subjected to bioautography using SMU, LA and LC. Conclusion: Anticariogenic activity and preliminary phytochemical analysis revealed that E. globule have potential to treat dental caries. PMID:26401353
Preparation, Characterization, and Preliminary In Vitro Testing of Nanoceria-Loaded Liposomes
Grillone, Agostina; Li, Tianshu; Battaglini, Matteo; Scarpellini, Alice; Takeoka, Shinji
2017-01-01
Cerium oxide nanoparticles (nanoceria), well known for their pro- and antioxidant features, have been recently proposed for the treatment of several pathologies, including cancer and neurodegenerative diseases. However, interaction between nanoceria and biological molecules such as proteins and lipids, short blood circulation time, and the need of a targeted delivery to desired sites are some aspects that require strong attention for further progresses in the clinical application of these nanoparticles. The aim of this work is the encapsulation of nanoceria into a liposomal formulation in order to improve their therapeutic potentialities. After the preparation through a reverse-phase evaporation method, size, Z-potential, morphology, and loading efficiency of nanoceria-loaded liposomes were investigated. Finally, preliminary in vitro studies were performed to test cell uptake efficiency and preserved antioxidant activity. Nanoceria-loaded liposomes showed a good colloidal stability, an excellent biocompatibility, and strong antioxidant properties due to the unaltered activity of the entrapped nanoceria. With these results, the possibility of exploiting liposomes as carriers for cerium oxide nanoparticles is demonstrated here for the first time, thus opening exciting new opportunities for in vivo applications. PMID:28926967
The fluid mechanics of channel fracturing flows: experiment
NASA Astrophysics Data System (ADS)
Rashedi, Ahmadreza; Tucker, Zachery; Ovarlez, Guillaume; Hormozi, Sarah
2017-11-01
We show our preliminary experimental results on the role of fluid mechanics in channel fracturing flows, particularly yield stress fracturing fluids. Recent trends in the oil industry have included the use of cyclic pumping of a proppant slurry interspersed with a yield stress fracturing fluid, which is found to increase wells productivity, if particles disperse in a certain fashion. Our experimental study aims to investigate the physical mechanisms responsible for dispersing the particles (proppant) within a yield stress carrier fluid, and to measure the dispersion of proppant slugs in various fracturing regimes. To this end we have designed and built a unique experimental setup that resembles a fracture configuration coupled with a particle image/tracking velocimetry setup operating at micro to macro dimensions. Moreover, we have designed optically engineered suspensions of complex fluids with tunable yield stress and consistency, well controlled density match-mismatch properties and refractive indices for both X-rays and visible lights. We present our experimental system and preliminary results. NSF (Grant No. CBET-1554044- CAREER), ACS PRF (Grant No. 55661-DNI9).
Rape-related cognitive distortions: Preliminary findings on the role of early maladaptive schemas.
Sigre-Leirós, Vera; Carvalho, Joana; Nobre, Pedro J
2015-01-01
Despite the important focus on the notion of cognitive distortions in the sexual offending area, the relevance of underlying cognitive schemas in sexual offenders has also been suggested. The aim of the present study was to investigate a potential relationship between Early Maladaptive Schemas (EMSs) and cognitive distortions in rapists. A total of 33 men convicted for rape completed the Bumby Rape Scale (BRS), the Young Schema Questionnaire - Short form-3 (YSQ-S3), the Brief Symptom Inventory (BSI), and the Socially Desirable Response Set Measure (SDRS-5). Results showed a significant relationship between the impaired limits schematic domain and the Justifying Rape dimension of the BRS. Specifically, after controlling for psychological distress levels and social desirability tendency, the entitlement/grandiosity schema from the impaired limits domain was a significant predictor of cognitive distortions related to Justifying Rape themes. Overall, despite preliminary, there is some evidence that the Young's Schema-Focused model namely the impaired limits dimension may contribute for the conceptualization of cognitive distortions in rapists and further investigation is recommended. Copyright © 2015 Elsevier Ltd. All rights reserved.
Moran, Lara; Andres, Sonia; Allen, Paul; Moloney, Aidan P
2018-08-01
Visible-near infrared spectroscopy (Vis-NIRS) has been suggested to have potential for authentication of food products. The aim of the present preliminary study was to assess if this technology can be used to authenticate the ageing time (3, 7, 14 and 21 days post mortem) of beef steaks from three different muscles (M. Longissimus thoracis, M. Gluteus medius and M. Semitendinosus). Various mathematical pre-treatments were applied to the spectra to correct scattering and overlapping effects, and then partial least squares-discrimination analysis (PLS-DA) procedures applied. The best models were specific for each muscle, and the ability of prediction of ageing time was validated using full (leave-one-out) cross-validation, whereas authentication performance was evaluated using the parameters of sensitivity, specificity and overall correct classification. The results indicate that overall correct classification ranging from 94.2 to 100% was achieved, depending on the muscle. In conclusion, Vis-NIRS technology seems a valid tool for the authentication of ageing time of beef steaks. Copyright © 2018 Elsevier Ltd. All rights reserved.
Vasudev, Akshya; Arena, Amanda; Burhan, Amer M; Ionson, Emily; Hirjee, Hussein; Maldeniya, Pramudith; Wetmore, Stephen; Newman, Ronnie I
2016-03-01
Late-life depression affects 2-6% of seniors aged 60 years and above. Patients are increasingly embracing non-pharmacological therapies, many of which have not been scientifically evaluated. This study aimed to evaluate a category of meditation, automatic self-transcending meditation (ASTM), in alleviating symptoms of depression when augmenting treatment as usual (NCT02149810). The preliminary results of an ongoing single-blind randomised controlled trial comparing a training programme involving ASTM with a wait-list control indicate that a 12-week ASTM programme may lead to significantly greater reductions in depression and anxiety severity. As such, ASTM may be an effective adjunctive therapy in the treatment of late-life depression. R.I.N. is Director of Research and Health Promotion for the Art of Living Foundation, Canada and supervised the staff providing ASTM training. © The Royal College of Psychiatrists 2016. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) licence.
Arena, Amanda; Burhan, Amer M.; Ionson, Emily; Hirjee, Hussein; Maldeniya, Pramudith; Wetmore, Stephen; Newman, Ronnie I.
2016-01-01
Late-life depression affects 2–6% of seniors aged 60 years and above. Patients are increasingly embracing non-pharmacological therapies, many of which have not been scientifically evaluated. This study aimed to evaluate a category of meditation, automatic self-transcending meditation (ASTM), in alleviating symptoms of depression when augmenting treatment as usual (NCT02149810). The preliminary results of an ongoing single-blind randomised controlled trial comparing a training programme involving ASTM with a wait-list control indicate that a 12-week ASTM programme may lead to significantly greater reductions in depression and anxiety severity. As such, ASTM may be an effective adjunctive therapy in the treatment of late-life depression. Declaration of interest R.I.N. is Director of Research and Health Promotion for the Art of Living Foundation, Canada and supervised the staff providing ASTM training. Copyright and usage © The Royal College of Psychiatrists 2016. This is an open access article distributed under the terms of the Creative Commons Non-Commercial, No Derivatives (CC BY-NC-ND) licence. PMID:27703774
Effects of nanotechnologies-based devices on postural control in healthy subjects.
Malchiodi Albedi, Giovanna; Corna, Stefano; Aspesi, Valentina; Clerici, Daniela; Parisio, Cinzia; Seitanidis, Jonathan; Cau, Nicola; Brugliera, Luigia; Capodaglio, Paolo
2017-09-05
The aim of the present preliminary randomized controlled study was to ascertain whether the use of newly developed nanotechnologies-based patches can influence posture control of healthy subjects. Thirty healthy female subjects (age 39.4 years, BMI 22.74 kg/m2) were randomly assigned to two groups: one with active patches and a control group with sham patches. Two patches were applied with a tape: one on the subject's sternum and the other on the C7 apophysis. Body sway during quiet upright stance was recorded with a dynamometric platform. Each subject was tested under two visual conditions, eyes open and closed. We used a blocked stratified randomization procedure conducted by a third party. Subjects wearing the sham patches showed a significant increase of the centre of pressure sway area after 4 hours when they performed the habitual moderate-intensity work activities. In the active patch group, a decrease of the sway path was evident, providing evidence of an enhanced balance control. Our preliminary findings on healthy subjects indicate that nanotechnological devices generating ultra-low electromagnetic fields can improve posture control.
Developing a disaster education program for community safety and resilience: The preliminary phase
NASA Astrophysics Data System (ADS)
Nifa, Faizatul Akmar Abdul; Abbas, Sharima Ruwaida; Lin, Chong Khai; Othman, Siti Norezam
2017-10-01
Resilience encompasses both the principles of preparedness and reaction within the dynamic systems and focuses responses on bridging the gap between pre-disaster activities and post-disaster intervention and among structural/non-structural mitigation. Central to this concept is the ability of the affected communities to recover their livelihood and inculcating necessary safety practices during the disaster and after the disaster strikes. While these ability and practices are important to improve the community safety and resilience, such factors will not be effective unless the awareness is present among the community. There have been studies conducted highlighting the role of education in providing awareness for disaster safety and resilience from a very young age. However for Malaysia, these area of research has not been fully explored and developed based on the specific situational and geographical factors of high-risk flood disaster locations. This paper explores the importance of disaster education program in Malaysia and develops into preliminary research project which primary aim is to design a flood disaster education pilot program in Kampung Karangan Primary School, Kelantan, Malaysia.
Laser microprobe characterization of C species in Interplanetary Dust Particles (IDP)
NASA Technical Reports Server (NTRS)
Dibrozolo, F. R.; Bunch, T. E.; Chang, S.; Brownlee, D. E.
1986-01-01
Preliminary results of a study whose aim is the characterization of carbon (C) species in microvolumes of materials by means of laser ionization mass spectrometry (LIMS) are presented. The LIMS instrument employs a pulsed UV laser to produce nearly instantaneous vaporization and ionization of materials, followed by acceleration and time-of-flight analysis of the ions produced. LIMS provides a survey technique with nearly simultaneous acquisition of mass spectra covering the entire elemental range. The main limitation of the LIMS technique at present is its limited ability to perform quantitative analysis, due in part to insufficient knowledge of the mechanism of laser-solid interaction. However, considerable effort is now being directed at making LIMS a more quantitative technique. A variety of different C samples, both natural and man made were analyzed to establish the ability of LIMS to differentiate among the various C phases. The results of preliminary analyses performed on meteoritical and interplanetary dust samples are also presented. The C standards selected for the LIMS characterization range from essentially amorphous soot to diamond, which exhibits the highest degree of ordering.
Ribeiro, Renato Cesar de Azevedo; Barreto, Stella Maria de Andrade Gomes; Ostrosky, Elissa Aarantes; da Rocha-Filho, Pedro Alves; Veríssimo, Lourena Mafra; Ferrari, Márcio
2015-02-02
This study aimed to produce and characterize an oil in water (O/W) nanoemulsion containing Opuntia ficus-indica (L.) Mill hydroglycolic extract, as well as evaluate its preliminary and accelerated thermal stability and moisturizing efficacy. The formulations containing 0.5% of xanthan gum (FX) and 0.5% of xanthan gum and 1% of Opuntia ficus-indica MILL extract (FXE) were white, homogeneus and fluid in aspect. Both formulations were stable during preliminary and accelerated stability tests. FX and FXE presented a pH compatible to skin pH (4.5-6.0); droplet size varying from 92.2 to 233.6 nm; a polydispersion index (PDI) around 0.200 and a zeta potential from -26.71 to -47.01 mV. FXE was able to increase the water content of the stratum corneum for 5 h after application on the forearm. The O/W nanoemulsions containing 1% of Opuntia ficus-indica (L.) Mill extract presented suitable stability for at least for 60 days. Besides, this formulation was able to increase the water content of stratum corneum, showing its moisturizing efficacy.
Developing a program for enhancing youth HIV treatment adherence and risk reduction.
Fongkaew, Warunee; Udomkhamsuk, Warawan; Viseskul, Nongkran; Guptaruk, Marisa
2017-12-01
Youth living with HIV face difficult and challenging situations that decrease their adherence to antiretroviral medications. In this study, we developed a pilot program to enhance HIV treatment adherence and risk reduction among youth living with HIV based on collaboration with a community hospital involving a multi-disciplinary healthcare team. Participants were 25 youth living with HIV/AIDS, 18 caregivers, and 12 healthcare providers. The action research process comprised a preliminary stage and four phases of assessment, planning, implementation, and evaluation. This program used "edutainment", participatory learning, and multi-disciplinary collaboration to improve HIV treatment adherence and HIV risk behavior knowledge, motivation, and behavior. Education aimed to improve knowledge of antiretroviral drugs and HIV risk-taking behaviors. Motivation was directed at reframing beliefs and increasing positive attitudes of youth toward treatment adherence and raising awareness about safer sex behaviors. The behavioral skills focused on medication management in daily life activities, problem-solving, refusal and negotiation, and condom use. Findings provided preliminary evidence that the program was practical in a clinical context in a community hospital. © 2017 John Wiley & Sons Australia, Ltd.
Gao, Fan; Rodriguez, Johanan; Kapp, Susan
2016-06-01
Harness fitting in the body-powered prosthesis remains more art than science due to a lack of consistent and quantitative evaluation. The aim of this study was to develop a mechanical, human-body-shaped apparatus to simulate body-powered upper limb prosthetic usage and evaluate its capability of quantitative examination of harness configuration. The apparatus was built upon a torso of a wooden mannequin and integrated major mechanical joints to simulate terminal device operation. Sensors were used to register cable tension, cable excursion, and grip force simultaneously. The apparatus allowed the scapula to move up to 127 mm laterally and the load cell can measure the cable tension up to 445 N. Our preliminary evaluation highlighted the needs and importance of investigating harness configurations in a systematic and controllable manner. The apparatus allows objective, systematic, and quantitative evaluation of effects of realistic harness configurations and will provide insightful and working knowledge on harness fitting in upper limb amputees using body-powered prosthesis. © The International Society for Prosthetics and Orthotics 2015.
Channel characterisation for future Ka-band Mobile Satellite Systems and preliminary results
NASA Technical Reports Server (NTRS)
Sforza, Mario; Buonomo, Sergio; Arbesser-Rastburg, Bertram
1994-01-01
Mobile satellite systems (MSS) are presently designed or planned to operate, with the exception of OMNITRACKS, in the lower part of the frequency spectrum (UHF to S-bands). The decisions taken at the last World Administrative Radio Conference in 1992 to increase the allocated L- and S-bands for MSS services will only partly alleviate the problem of system capacity. In addition the use of L-and S-band frequencies generally requires large antenna apertures on board the satellite terminal side. The idea of exploiting the large spectrum resources available at higher frequencies (20-30 GHz) and the perspective of reducing user terminal size (and possibly price too) have spurred the interest of systems designers and planners. On the other hand, Ka-band frequencies suffer from increased slant path losses due to atmospheric attenuation phenomena. The European Space Agency (ESA) has recently embarked on a number of activities aimed at studying the effect of the typical mobile propagation impairments at Ka-band. This paper briefly summarizes ESA efforts in this field of research and presents preliminary experimental results.
Wojtłowska-Wiechetek, D; Tworus, R; Dziuk, M; Petrovic, A; Szymańska, S; Zbyszewski, M; Ilnicki, S; Krzesiński, P
2013-01-01
The aim of this study was to evaluate the possibility of using PET both in assessing the susceptibility to stress and in the diagnosis of post-traumatic stress disorders. Mentally and somatically healthy soldiers were subjected to PET-CT head scan examinations before and after virtual reality stimulation with warfare scenarios. Despite stimulation of peripheral nervous system after 10 minutes, VR exposure in any of the examined soldiers simulation did not cause changes in any brain structure that was visualized in PET. PET-CT head scan was also performed in patients with typical symptoms of acute PTSD according to the criteria of DSM IV TR. In those patients no changes in any brain structure was found. Initially it was found that VR exposure techniques like clinically typical acute symptoms of PTSD do not leave changes in CNS, which could be visualized in PET. The preliminary hypothesis was put forward that exposure to stimuli like symptoms of PTSD must remain long enough to induce permanent damage of brain structure.
Risk and protective factors for sexual risk taking among adolescents involved in Prime Time.
Garwick, Ann; Nerdahl, Peggy; Banken, Rachel; Muenzenberger-Bretl, Lynn; Sieving, Renee
2004-10-01
This article describes a preliminary qualitative evaluation of risk and protective factors associated with consistent contraceptive use and healthy sexual decision-making among ten of the first participants in the Prime Time intervention study. Prime Time is an 18-month intervention including one-on-one case management and peer educator training targeting sexually active 13-17-year-old girls who are recruited from health care clinics. Using an approach grounded in findings from previous research, social cognitive theory, and the social development model, Prime Time aims to improve participants' contraceptive use consistency, reduce number of sexual partners, and reduce unwanted sexual activity. Findings from this preliminary evaluation alert health care providers to the complex and dynamic nature of adolescent girls' sexual behaviors and to a broad range of risk and protective factors within individuals and their environments that may influence adolescent girls' sexual behaviors and contraceptive use. Findings suggest that an ongoing, supportive relationship with a case manager who is able to pace and tailor an intervention to the individual young person can have positive effects on adolescent girls' sexual behaviors and contraceptive use.
MRI and clinical features of maple syrup urine disease: preliminary results in 10 cases.
Cheng, Ailan; Han, Lianshu; Feng, Yun; Li, Huimin; Yao, Rong; Wang, Dengbin; Jin, Biao
2017-01-01
We aimed to evaluate the magnetic resonance imaging (MRI) and clinical features of maple syrup urine disease (MSUD). This retrospective study consisted of 10 MSUD patients confirmed by genetic testing. All patients underwent brain MRI. Phenotype, genotype, and areas of brain injury on MRI were retrospectively reviewed. Six patients (60%) had the classic form of MSUD with BCKDHB mutation, three patients (30%) had the intermittent form (two with BCKDHA mutations and one with DBT mutation), and one patient (10%) had the thiamine-responsive form with DBT mutation. On diffusion-weighted imaging, nine cases presented restricted diffusion in myelinated areas, and one intermittent case with DBT mutation was normal. The classic form of MSUD involved the basal ganglia in six cases; the cerebellum, mesencephalon, pons, and supratentorial area in five cases; and the thalamus in four cases, respectively. The intermittent form involved the cerebellum, pons, and supratentorial area in two cases. The thiamine-responsive form involved the basal ganglia and supratentorial area. Our preliminary results indicate that patients with MSUD presented more commonly in classic form with BCKDHB mutation and displayed extensive brain injury on MRI.
NASA Astrophysics Data System (ADS)
Remy, Samuel; Benedetti, Angela; Jones, Luke; Razinger, Miha; Haiden, Thomas
2014-05-01
The WMO-sponsored Working Group on Numerical Experimentation (WGNE) set up a project aimed at understanding the importance of aerosols for numerical weather prediction (NWP). Three cases are being investigated by several NWP centres with aerosol capabilities: a severe dust case that affected Southern Europe in April 2012, a biomass burning case in South America in September 2012, and an extreme pollution event in Beijing (China) which took place in January 2013. At ECMWF these cases are being studied using the MACC-II system with radiatively interactive aerosols. Some preliminary results related to the dust and the fire event will be presented here. A preliminary verification of the impact of the aerosol-radiation direct interaction on surface meteorological parameters such as 2m Temperature and surface winds over the region of interest will be presented. Aerosol optical depth (AOD) verification using AERONET data will also be discussed. For the biomass burning case, the impact of using injection heights estimated by a Plume Rise Model (PRM) for the biomass burning emissions will be presented.
Preliminary normative data on the BORB for children aged 3-8.
Brunsdon, Ruth; Joy, Pamela; Patten, Erin; Burton, Karen
2018-05-09
The Birmingham Object Recognition Battery (BORB) is a theoretically based test battery that is used in adult cognitive neuropsychology in research and for clinical assessment. It allows a detailed analysis of underlying impairments in individuals with brain injury who have visual object recognition difficulties. The BORB's usefulness in pediatrics is supported by numerous research studies. However, there is no published normative data for children, making clinical use of the test difficult. The aim of this brief report is to publish some preliminary normative data in 70 children aged between 3 and 8 years to assist both researchers and clinicians with interpretation of test scores. Results indicate that children's performance on individual BORB subtests varies according to task demands and age. For some subtests there is improvement in performance with increasing age. However, very young children (age 3-4 years) perform at adult levels on some subtests, or alternatively on other subtests they perform at the level of chance. The current paper supports the need for pediatric data for the BORB due to large normal individual variation in performance and varying age-related performance on individual BORB subtests.
Preliminary estimates of the economic implications of addiction in the United Arab Emirates.
Doran, C M
2017-01-23
This study aimed to provide preliminary estimates of the economic implications of addiction in the United Arab Emirates (UAE). Local and international data sources were used to derive estimates of substancerelated healthcare costs, lost productivity and criminal behaviour. From an estimated population of 8.26 million: ~1.47 million used tobacco (20.5% of adults); 380 085 used cannabis (> 5%); 14 077 used alcohol in a harmful manner (0.2%); and 1408 used opiates (0.02%). The cost of addiction was estimated at US$ 5.47 billion in 2012, equivalent to 1.4% of gross domestic product. Productivity costs were the largest contributor at US$ 4.79 billion (88%) followed by criminal behaviour at US$ 0.65 billion (12%). There were no data to estimate cost of: treating tobacco-related diseases, community education and prevention efforts, or social disharmony. Current data collection efforts are limited in their capacity to fully inform an appropriate response to addiction in the UAE. Resources are required to improve indicators of drug use, monitor harm and evaluate treatment.
Ramacciotti, C E; Perrone, P; Coli, E; Burgalassi, A; Conversano, C; Massimetti, G; Dell'Osso, L
2011-06-01
Orthorexia, from the Greek words orthos (straight, proper) and orexis (appetite), is a newly conceptualized disorder characterized by distorted eating habits and cognitions concerning supposedly healthy nutrition. In this article we present preliminary results of a wider research aimed to investigate the diffusion of Orthorexia in the general population and to highlight its characteristics and particularly the relationship with Eating Disorder and Obsessive-Compulsive Disorder. One-hundred and seventy seven adult subjects from the general population, were administered the ORTO-15 test, a selfadministered questionnaire specifically designed to assess orthorexic symptomatology; note that statistical analyses were repeated twice, referring to different diagnostic thresholds (40/35). Orthorexia had a 57.6% prevalence in our sample, using the 40-point threshold, with a female/male ratio 2:1; the figure was sensibly lower with the 35-point threshold (21%). The results of this study highlight the diffusion of Orthorexia which may constitute an important risk factor for mental and physical health, but also the opportunity of more specific diagnostic instruments, so to facilitate a thorough understanding of this disorder.
Navarro, Esperanza; Castelló, Ana; López, Jose L; Verdú, Fernando
2006-04-20
Latent prints are an important evidence for identification. Nowadays, the technical means, the implementation of image processing techniques and the use of database makes it possible to detect and get information from some prints that seem to be useless at first sight. On the other hand, the possibility of using the print as a DNA source has to be considered, so as to double its identifying value. Human skin is a particularly difficult surface for developing this kind of evidences. Although different methods for locating and developing latent fingerprints on the skin have been already described, it has not been found any method, at the revised bibliography, to obtain and develop invisible lipmarks, that is, lipmarks from protective lipstick, or permanent or long-lasting lipstick. The aim of the work that follows is to determine the effectiveness of several reagents for developing invisible lipmarks on the corpses' skin. Preliminary results show that, under the described experimental conditions, the reagents used, Sudan III, Oil Red O and Sudan Black, are effective for obtaining recent latent lip prints on corpse's skin.
Alessandrini, Marco; Pavone, Isabella; Micarelli, Alessandro; Caporale, Claudio
2017-09-13
Considering the emerging advantages related to da Vinci Xi robotic platform, the aim of this study is to compare for the first time the operative outcomes of this tool to the previous da Vinci Si during transoral robotic surgery (TORS), both performed for squamous cell carcinomas (SCC) of the base of tongue (BOT). Intra- and peri-operative outcomes of eight patients with early stage (T1-T2) of the BOT carcinoma and undergoing TORS by means of the da Vinci Xi robotic platform (Xi-TORS) are compared with the da Vinci Si group ones (Si-TORS). With respect to Si-TORS group, Xi-TORS group demonstrated a significantly shorter overall operative time, console time, and intraoperative blood loss, as well as peri-operative pain intensity and length of mean hospital stays and nasogastric tube positioning. Considering recent advantages offered by surgical robotic techniques, the da Vinci Xi Surgical System preliminary outcomes could suggest its possible future routine implementation in BOT squamous cell carcinoma procedures.
Herrero, Rocio; García-Palacios, Azucena; Castilla, Diana; Molinari, Guadalupe; Botella, Cristina
2014-06-01
One of the most important aspects of fibromyalgia syndrome (FMS) is its impact on quality of life, increasing negative emotions and dysfunctional coping strategies. One of these strategies is to avoid activities, especially meaningful activities, which reduces positive reinforcement. Commencing significant daily activities could enable chronic patients to experience a more fulfilling life. However, the main difficulty found in FMS patients is their willingness to start those activities. Promoting positive emotions could enhance activity management. The aim of this paper is to present a description of a system along with data regarding the acceptability, satisfaction, and preliminary efficacy of a virtual reality (VR) environment for the promotion of positive emotions. The VR environment was especially designed for chronic pain patients. Results showed significant increases in general mood state, positive emotions, motivation, and self-efficacy. These preliminary findings show the potential of VR as an adjunct to the psychological treatment of such an important health problem as chronic pain.
Unfinished Business in Bereavement
Klingspon, Kara L.; Holland, Jason M.; Neimeyer, Robert A.; Lichtenthal, Wendy G.
2016-01-01
Unfinished business (incomplete, unexpressed or unresolved relationship issues with the deceased) is frequently discussed as a risk factor for chronic and severe grief reactions. However, few empirical studies have examined this construct. The present study aimed to address this gap in the literature by examining the presence and severity of unfinished business as well as common themes of unfinished business reported in open-ended qualitative narratives among a sample of 224 bereaved individuals. In bivariate analyses, self-reported presence of unfinished business and the severity of distress due to unfinished business were both found to be associated with poorer bereavement outcomes. However, after controlling for potential confounds, distress related to unresolved issues with the deceased emerged as a more robust correlate of these outcomes. Qualitative responses were categorized, and the type of reported unfinished business was not significantly related to the degree of unfinished business distress or other bereavement outcomes. These findings provide preliminary justification for bereavement interventions that aim to ameliorate distress related to unresolved relational issues with the deceased. PMID:26057117
Unfinished Business in Bereavement.
Klingspon, Kara L; Holland, Jason M; Neimeyer, Robert A; Lichtenthal, Wendy G
2015-01-01
Unfinished business (incomplete, unexpressed or unresolved relationship issues with the deceased) is frequently discussed as a risk factor for chronic and severe grief reactions. However, few empirical studies have examined this construct. The present study aimed to address this gap in the literature by examining the presence and severity of unfinished business as well as common themes of unfinished business reported in open-ended qualitative narratives among a sample of 224 bereaved individuals. In bivariate analyses, self-reported presence of unfinished business and the severity of distress due to unfinished business were both found to be associated with poorer bereavement outcomes. However, after controlling for potential confounds, distress related to unresolved issues with the deceased emerged as a more robust correlate of these outcomes. Qualitative responses were categorized, and the type of reported unfinished business was not significantly related to the degree of unfinished business distress or other bereavement outcomes. These findings provide preliminary justification for bereavement interventions that aim to ameliorate distress related to unresolved relational issues with the deceased.
Concu, Giovanna; De Nicolo, Barbara; Valdes, Monica
2014-01-01
The aim of this study was to evaluate ultrasonic P-wave velocity as a feature for predicting some physical and mechanical properties that describe the behavior of local building limestone. To this end, both ultrasonic testing and compressive tests were carried out on several limestone specimens and statistical correlation between ultrasonic velocity and density, compressive strength, and modulus of elasticity was studied. The effectiveness of ultrasonic velocity was evaluated by regression, with the aim of observing the coefficient of determination r 2 between ultrasonic velocity and the aforementioned parameters, and the mathematical expressions of the correlations were found and discussed. The strong relations that were established between ultrasonic velocity and limestone properties indicate that these parameters can be reasonably estimated by means of this nondestructive parameter. This may be of great value in a preliminary phase of the diagnosis and inspection of stone masonry conditions, especially when the possibility of sampling material cores is reduced. PMID:24511286
Concu, Giovanna; De Nicolo, Barbara; Valdes, Monica
2014-01-01
The aim of this study was to evaluate ultrasonic P-wave velocity as a feature for predicting some physical and mechanical properties that describe the behavior of local building limestone. To this end, both ultrasonic testing and compressive tests were carried out on several limestone specimens and statistical correlation between ultrasonic velocity and density, compressive strength, and modulus of elasticity was studied. The effectiveness of ultrasonic velocity was evaluated by regression, with the aim of observing the coefficient of determination r(2) between ultrasonic velocity and the aforementioned parameters, and the mathematical expressions of the correlations were found and discussed. The strong relations that were established between ultrasonic velocity and limestone properties indicate that these parameters can be reasonably estimated by means of this nondestructive parameter. This may be of great value in a preliminary phase of the diagnosis and inspection of stone masonry conditions, especially when the possibility of sampling material cores is reduced.
Cailhol, Lionel; Allen, Michael; Moncany, Anne-Hélène; Cicotti, Andrei; Virgillito, Salvatore; Barbe, Rémy P; Lazignac, Coralie; Damsa, Cristian
2007-01-01
In spite of much effort to create guidelines on the management of violent behavior (VB) in emergency departments, little is known about the impact of such guidelines on a real-life emergency environment. The aim of this study is to investigate the impact of a staff educational crisis intervention (SECI) on the reduction of VB in patients admitted to emergency departments following drug suicidal attempt. The impact of a SECI on VB of patient consulting the ER following a drug suicide attempt was assessed by comparing the occurrence of VB before (5 months) and after (5 months) the introduction of a SECI. A significant reduction in VB (from 17.32% to 7.14%) was found with the comparison of two 5-month periods: before (254 patients) and after (224 patients) the introduction of a SECI program (chi(2)=11.238; P=.0008). These preliminary data suggest the need for further prospective randomized studies aiming to prevent VB in emergency departments by developing specific SECI programs.
Effects of imatinib and nilotinib on the whole transcriptome of cultured murine osteoblasts.
Kirschner, Gyöngyi; Balla, Bernadett; Horváth, Péter; Kövesdi, Andrea; Lakatos, Gergely; Takács, István; Nagy, Zsolt; Tóbiás, Bálint; Árvai, Kristóf; Kósa, János Pál; Lakatos, Péter
2016-09-01
Numerous clinical observations have confirmed that breakpoint cluster region-abelson fusion oncoprotein tyrosine kinase inhibitors used in leukemia treatment alter bone physiology in a complex manner. The aim of the present study was to analyze the whole transcriptome of cultured murine osteoblasts and determine the changes following treatment with imatinib and nilotinib using Sequencing by Oligonucleotide Ligation and Detection next generation RNA sequencing. This study also aimed to identify candidate signaling pathways and network regulators by multivariate Ingenuity Pathway Analysis. Based on the right-tailed Fisher's exact test, significantly altered pathways including upstream regulators were defined for each drug. The correlation between these pathways and bone metabolism was also examined. The preliminary results suggest the two drugs have different mechanisms of action on osteoblasts, and imatinib was shown to have a greater effect on gene expression. Data also indicated the potential role of a number of genes and signaling cascades that may contribute to identifying novel targets for the treatment of metabolic bone diseases.
The impact of precommitment on risk-taking while gambling: A preliminary study.
Brevers, Damien; Noel, Xavier; Clark, Luke; Zyuzin, Jekaterina; Justin Park, Joohwan; Bechara, Antoine
2016-03-01
Background and aims Precommitment refers to the ability to prospectively restrict the access to temptations. This study examined whether risk-taking during gambling is decreased when an individual has the opportunity to precommit to his forthcoming bet. Methods Sixty individuals participated in a gambling task that consisted of direct choice (simply chose one monetary option among four available ones, ranging from low-risk to high-risk options) or precommitment trials (before choosing an amount, participants had the opportunity to make a binding choice that made high-risk options unavailable). Results We found that participants utilized the precommitment option, such that risk-taking was decreased on precommitment trials compared to direct choices. Within the precommitment trials, there was no significant difference in risk-taking following decisions to restrict versus non-restrict. Discussion These findings suggest that the opportunity to precommit may be sufficient to reduce the attractiveness of risk. Conclusions Present results might be exploited to create interventions aiming at enhancing one's ability to anticipate self-control failures while gambling.
Stringer, Barbara; van Meijel, Berno; Karman, Pieter; Koekkoek, Bauke; Hoogendoorn, Adriaan W; Kerkhof, Ad J F M; Beekman, Aartjan T F
2015-07-01
To test if a collaborative care program (CCP) with nurses in a coordinating position is beneficial for patients with severe personality disorders. A pilot study with a comparative multiple case study design using mixed methods investigating active ingredients and preliminary results. Most patients, their informal caregivers, and nurses value (parts of) the CCP positively; preliminary results show a significant decrease in severity of borderline symptoms. With the CCP, we may expand the supply of available treatments for patients with (severe) personality disorders, but a larger randomized controlled trial is warranted to confirm our preliminary results. © 2014 Wiley Periodicals, Inc.
ERIC Educational Resources Information Center
Hamburg, Morris; And Others
The long-term goal of this investigation is to design and establish a national model for a system of library statistical data. This is a report on The Preliminary Study which was carried out over an 11-month period ending May, 1969. The objective of The Preliminary Study was to design and delimit The Research Investigation in the most efficient…
Leblanc, Élizabel; Dégeilh, Fanny; Daneault, Véronique; Beauchamp, Miriam H.; Bernier, Annie
2017-01-01
A large body of longitudinal research provides compelling evidence for the critical role of early attachment relationships in children’s social, emotional, and cognitive development. It is expected that parent–child attachment relationships may also impact children’s brain development, however, studies linking normative caregiving experiences and brain structure are scarce. To our knowledge, no study has yet examined the associations between the quality of parent–infant attachment relationships and brain morphology during childhood. The aim of this preliminary study was to investigate the prospective links between mother–infant attachment security and whole-brain gray matter (GM) volume and thickness in late childhood. Attachment security toward the mother was assessed in 33 children when they were 15 months old. These children were then invited to undergo structural magnetic resonance imaging at 10–11 years of age. Results indicated that children more securely attached to their mother in infancy had larger GM volumes in the superior temporal sulcus and gyrus, temporo-parietal junction, and precentral gyrus in late childhood. No associations between attachment security and cortical thickness were found. If replicated, these results would suggest that a secure attachment relationship and its main features (e.g., adequate dyadic emotion regulation, competent exploration) may influence GM volume in brain regions involved in social, cognitive, and emotional functioning through experience-dependent processes. PMID:29312029
Perlis, Michael; Grandner, Michael; Zee, Jarcy; Bremer, Erin; Whinnery, Julia; Barilla, Holly; Andalia, Priscilla; Gehrman, Phil; Morales, Knashawn; Thase, Michael; Bootzin, Richard; Ader, Robert
2015-09-01
At present, there is no consensus regarding how to medically manage chronic insomnia in the long term. The unstated standard of practice is for patients to use hypnotics intermittently. The present study aimed to compare a partial reinforcement strategy with nightly and intermittent dosing strategies for its potential as a maintenance therapy. A mixed model was used in the study. One between-subjects factor: group (n = 4). One repeated-measures factor: time (12 weekly assessments). A total of 74 subjects with chronic Insomnia were treated with 10 mg zolpidem for 4 weeks. Treatment respondents were randomized to nightly dosing with 10 mg or 5 mg (QHS-10 and QHS-5), intermittent dosing with 10 mg (IDS-10 [3-5 days weekly]), or partial reinforcement dosing with 10 mg (PRS-10 [nightly pill use with 50% active medication and 50% placebos]) for 12 weeks. It was found, in compliant subjects (n = 55), that all four strategies evaluated maintained treatment response over time (ie, prevented or delayed relapse). For the subjects that remained in remission, the subjects in the intermittent dosing group (IDS-10) group exhibited poorer sleep continuity. While best considered a preliminary study, the present findings suggest that the partial reinforcement strategy may be a viable means toward maintaining treatment gains over time with less active medication. Copyright © 2015. Published by Elsevier B.V.
Choi, Moo Jin; Choi, Byung Tae; Shin, Hwa Kyoung; Shin, Byung Cheul; Han, Yoo Kyoung; Baek, Jin Ung
2015-01-01
The major objectives of this study were to provide a list of candidate antiaging medicinal herbs that have been widely utilized in Korean medicine and to organize preliminary data for the benefit of experimental and clinical researchers to develop new drug therapies by analyzing previous studies. “Dongeuibogam,” a representative source of the Korean medicine literature, was selected to investigate candidate antiaging medicinal herbs and to identify appropriate terms that describe the specific antiaging effects that these herbs are predicted to elicit. In addition, we aimed to review previous studies that referenced the selected candidate antiaging medicinal herbs. From our chosen source, “Dongeuibogam,” we were able to screen 102 terms describing antiaging effects, which were further classified into 11 subtypes. Ninety-seven candidate antiaging medicinal herbs were selected using the criterion that their antiaging effects were described using the same terms as those employed in “Dongeuibogam.” These candidates were classified into 11 subtypes. Of the 97 candidate antiaging medicinal herbs selected, 47 are widely used by Korean medical doctors in Korea and were selected for further analysis of their antiaging effects. Overall, we found an average of 7.7 previous studies per candidate herb that described their antiaging effects. PMID:25861371
Talfournier, J; Bitu, J; Paquet, C; Gobron, C; Guillausseau, P J; Hugon, J; Dumurgier, J
2013-10-01
This study aimed to assess the relationship between blood pressure and cognitive function in elderly patients with diabetes mellitus (DM). A total of 32 patients with DM aged ≥ 65 years (seven women and 25 men; mean ± SD age: 74.3 ± 6.4 years) were included in this cross-sectional study. Relationships between blood pressure and neuropsychological tests were determined using Spearman's rank correlations (ρ) and multivariable linear regression models. Lower diastolic blood pressure was associated with lower scores on the Frontal Assessment Battery (ρ=0.32, P=0.02), longer times to complete the Trail Making Test Part B (ρ=0.51, P=0.003), lower scores for the Finger Tapping Test (ρ=0.36, P=0.046) and less verbal fluency (ρ=0.36, P=0.047). In multivariable models, these relationships were attenuated after adjusting for levels of education. There was an association between lower diastolic blood pressure and poorer executive function in this cohort of elderly DM patients. These results underline the importance of systematic cognitive evaluation in elderly patients with DM, and suggest that a too-low diastolic blood pressure may have deleterious effects on mental function. Larger studies in the future are required to confirm these preliminary results. Copyright © 2013 Elsevier Masson SAS. All rights reserved.
NASA Astrophysics Data System (ADS)
Goodell, Teresa T.; Bargo, Paulo R.; Jacques, Steven L.
2002-06-01
Background: Subjective measures are considered the gold standard in palliative care evaluation, but no studies have evaluated palliative photodynamic therapy (PDT) subjectively. If PDT is to be accepted as a palliative therapy for later-stage obstructing esophageal and lung cancer, evidence of its effectiveness and acceptability to patients must be made known. Study Design/Materials and Methods: This ongoing study's major aim is to evaluate subjective outcomes of PDT in patients with obstructing esophageal and lung cancer. Existing measures of health status, dysphagia and performance status were supplemented with an instrument developed to evaluate PDT symptom relief and side effect burden, the PDT Side Effects Survey (PSES). Results: PDT patients treated with porfimer sodium (Photofrin) and 630-nm light experienced reduced dysphagia grade and stable performance status for at least one month after PDT (N= 10-17), but these effects did not necessarily persist at three months. Fatigue, appetite and quality of life may be the most burdensome issues for these patients. Conclusions: Preliminary data suggest that the PSES is an acceptable and valid tool for measuring subjective outcomes of palliative PDT. This study is the first attempt to systematically evaluate subjective outcomes of palliative PDT. Multi-center outcomes research is needed to draw generalizable conclusions that will establish PDT's effectiveness in actual clinical practice and enhance the wider adoption of PDT as a cancer symptom relief modality.
NASA Astrophysics Data System (ADS)
Indrianingsih, A. W.; Rosyida, V. T.; Jatmiko, T. H.; Prasetyo, D. J.; Poeloengasih, C. D.; Apriyana, W.; Nisa, K.; Nurhayati, S.; Hernawan; Darsih, C.; Pratiwi, D.; Suwanto, A.; Ratih, D.
2017-12-01
Bacterial cellulose produced by Acetobacter xylinum is a unique type of bacterial cellulose. It contains more than 90% of water. A preliminary study had shown that bacterial cellulose films has remarkable mechanical properties. The aim of this study was to investigate the optimum condition such as percentage of carbon source, time of cultivation, and pH to produce bacterial cellulose films from local coconut water, and its characterization on morphology, swelling ability and tensile strength of dried bacterial cellulose. A. xylinum was grown on coconut water culture medium with addition of 3%, 5%, and 7% of sugar, while the cultivation time was vary from 3 days, 5 days and 7 days. pH condition was conducted in pH 3, pH 5 and pH 7. Bacterial cellulose samples were dried using oven with temperature of 100°C until the moisture content reached 4-5%. This study showed that several parameters for optimum condition to produce bacterial cellulose films from local waste of coconut water had been obtained (5% of carbon source; pH 5; and 7 day of incubation period). The electron microscopy also showed that dried bacterial cellulose films had pores covered by fibrils on the surface. Therefore, the present work proposes the optimum formula and condition that can be used based on properties of end product needed.
Toglia, Joan; Johnston, Mark V; Goverover, Yael; Dain, Barry
2010-01-01
Persons with brain injury frequently demonstrate decreased ability to monitor and apply strategies learned in treatment to everyday situations. The aim of this study is to refine, explore and provide preliminary testing of the multicontext approach in promoting strategy use across situations and increasing self-regulation, awareness and functional performance. This study used a single-subject design with repeated measures pre- and post-intervention, with data analysed descriptively and graphically. Four persons with difficulty following multi-step directions, 3-5 years post-TBI, received a nine session intervention programme. Outcome measures included the Awareness Questionnaire, Self-Regulation Skills Interview, Behavior Rating Inventory of Executive Function, Multiple Errands Test and an Executive Function Performance Test sub-task. The process of change within each treatment session was examined with strategy and awareness ratings. All participants demonstrated positive changes in self-regulatory skills and strategy use that was observed across tasks. As expected, general awareness of deficits remained unchanged. Examination of individual participants revealed important, varying patterns of change in strategy use, learning transfer and self-awareness across intervention. Results provide preliminary support for the feasibility and efficacy of the multicontext approach in promoting transfer of strategy use to enhance functional performance and selective aspects of awareness. Further investigation, including a larger controlled study, is needed to confirm or limit these observations.
McAndrew, Amy; Lawn, Will; Stevens, Tobias; Porffy, Lilla; Brandner, Brigitta; Morgan, Celia J A
2017-04-04
Worldwide, alcohol abuse is a burgeoning problem. Abstinence is key to allow recovery of physical and mental health as well as quality of life, but treatment for alcohol dependence is associated with high relapse rates. Preliminary data have suggested that a combined repeated ketamine and psychological therapy programme may be effective in reducing relapse in severe alcohol use disorder. This non-commercial proof-of-concept trial is aimed at making a preliminary assessment of the effectiveness of this combined treatment in this patient group. This is a phase II, randomised, double-blind, placebo-controlled, parallel-group clinical trial taking place in two sites in the UK: the South West of England and London. Ninety-six recently detoxified alcoholics, with comorbid depressive symptoms, will be randomised to one of four treatment arms. Patients will receive either three sessions of ketamine (0.8 mg/kg administered intravenously (IV) over 40 minutes) or placebo (50 ml saline 0.9% IV over 40 minutes) plus either seven sessions of manualised psychological therapy or an alcohol education control. Patients will be assessed at 3 and 6 months on a range of psychological and biological variables. The primary endpoints are (1) relapse rates at 6 months and (2) percentage days abstinent at 6 months. Secondary endpoints include 3 and 6 month percentage days abstinence, tolerability (indicated by dropout), adverse events, depressive symptoms, craving and quality of life. This study will provide important information on a new combined psychological and pharmacological intervention aimed at reducing relapse rates in alcoholics. The findings would have broad application given the worldwide prevalence of alcoholism and its associated medical, psychological and social problems. ClinicalTrials.gov, NCT02649231 . Registered on 5 January 2016.
ERIC Educational Resources Information Center
Bormann, Inka; Michelsen, Gerd
2010-01-01
This article introduces a tri-national research and development project which aims to develop indicators for the cross-sectoral and interdisciplinary educational task "education for sustainable development" (ESD). These indicators are meant to help monitor the implementation of ESD efforts in schools and institutions of higher education…
Pathfinders: A Self-Care and Health Education Program for Older Widows and Widowers.
ERIC Educational Resources Information Center
Caserta, Michael S.; Lund, Dale A.; Rice, Sarah Jane
1999-01-01
Describes a research-based self-care health education program for recently widowed people. Program aims to provide a foundation of knowledge, motivation, and encouragement to initiate positive behavioral changes, and to establish a support network. Preliminary analysis suggests the program is achieving many of the intended outcomes. (Author/JDM)
Virtually Nursing: Emerging Technologies in Nursing Education.
Foronda, Cynthia L; Alfes, Celeste M; Dev, Parvati; Kleinheksel, A J; Nelson, Douglas A; OʼDonnell, John M; Samosky, Joseph T
Augmented reality and virtual simulation technologies in nursing education are burgeoning. Preliminary evidence suggests that these innovative pedagogical approaches are effective. The aim of this article is to present 6 newly emerged products and systems that may improve nursing education. Technologies may present opportunities to improve teaching efforts, better engage students, and transform nursing education.
James B. Baker
1994-01-01
In August 1990, USDA Forest Service researchers from the Southern Forest Experiment Station and resource managers from the Ouachita and Ozark National Forests embarked on a major ecosystem management (then called New Perspectives) research program aimed at formulating, implementing, and evaluating partial cutting methods in shortleaf pine-hardwood stands as...
Narrative and the Origins of Discourse: Patterns of Discourse in Stories around the World
ERIC Educational Resources Information Center
Rose, David
2005-01-01
This paper summarises findings of discourse analyses of traditional stories from eleven language phyla around the world. The aim is a preliminary exploration of relationships amongst diverse languages in patterns of discourse, using a systemic functional language model. Several techniques were developed for managing and displaying the analyses,…
ERIC Educational Resources Information Center
Johnson, Genevieve Marie
2015-01-01
In higher education, assessment integrity is pivotal to student learning and satisfaction, and, therefore, a particularly important target of continuous quality improvement. This paper reports on the preliminary development and application of a process of recording and analysing current assessment moderation practices, with the aim of identifying…
Game Creation in Youth Media and Information Literacy Education
ERIC Educational Resources Information Center
Costa, Conceição; Tyner, Kathleen; Henriques, Sara; Sousa, Carla
2018-01-01
This article presents the preliminary findings of GamiLearning (2015-2018), a research project that aims to promote critical and participative dimensions of Media and Information Literacy (MIL) in children through the creation of digital games. The project presents an innovative approach by arguing that MIL can be promoted through the process of…
Measuring general relativity effects in a terrestrial lab by means of laser gyroscopes
NASA Astrophysics Data System (ADS)
Beverini, N.; Allegrini, M.; Beghi, A.; Belfi, J.; Bouhadef, B.; Calamai, M.; Carelli, G.; Cuccato, D.; Di Virgilio, A.; Maccioni, E.; Ortolan, A.; Porzio, A.; Santagata, R.; Solimeno, S.; Tartaglia, A.
2014-07-01
GINGER is a proposed tridimensional array of laser gyroscopes with the aim of measuring the Lense-Thirring effect, predicted by the general relativity theory, in a terrestrial laboratory environment. We discuss the required accuracy, the methods to achieve it, and the preliminary experimental work in this direction.
Escalante, Yolanda; Saavedra, Jose M; Tella, Victor; Mansilla, Mirella; García-Hermoso, Antonio; Domínguez, Ana M
2013-04-01
The aims of this study were (a) to compare water polo game-related statistics by context (winning and losing teams) and phase (preliminary, classification, and semifinal/bronze medal/gold medal), and (b) identify characteristics that discriminate performances for each phase. The game-related statistics of the 230 men's matches played in World Championships (2007, 2009, and 2011) and European Championships (2008 and 2010) were analyzed. Differences between contexts (winning or losing teams) in each phase (preliminary, classification, and semifinal/bronze medal/gold medal) were determined using the chi-squared statistic, also calculating the effect sizes of the differences. A discriminant analysis was then performed after the sample-splitting method according to context (winning and losing teams) in each of the 3 phases. It was found that the game-related statistics differentiate the winning from the losing teams in each phase of an international championship. The differentiating variables are both offensive and defensive, including action shots, sprints, goalkeeper-blocked shots, and goalkeeper-blocked action shots. However, the number of discriminatory variables decreases as the phase becomes more demanding and the teams become more equally matched. The discriminant analysis showed the game-related statistics to discriminate performance in all phases (preliminary, classificatory, and semifinal/bronze medal/gold medal phase) with high percentages (91, 90, and 73%, respectively). Again, the model selected both defensive and offensive variables.
Exploring the temperament and character traits of rural and urban doctors.
Eley, Diann; Young, Louise; Przybeck, Thomas R
2009-01-01
Australia shares many dilemmas with North America regarding shortages of doctors in rural and remote locations. This preliminary study contributes to the establishment of a psychobiological profile for rural doctors by comparing temperament and character traits with an urban cohort. The aim was to compare the individual levels and combinations of temperament (mildly heritable and stable) and character (developmental and modifiable) traits of rural and urban general practitioners (GPs). Rural (n = 120) and urban (n = 94) GPs completed a demographic questionnaire and the TCI-R 140 to identify levels of the 7 basic dimensions of temperament and character. These are Novelty Seeking (NS), Harm Avoidance (HA), Reward Dependence (RD), Persistence (PS), Self-Directedness (SD), Cooperativeness (CO), and Self-Transcendence (ST). Preliminary results show rural GPs were higher in the temperament traits of NS and lower in HA compared with the urban sample. All female GPs were higher in RD and CO compared with all males, and all older GPs (over 55 years) were lower in RD compared with all younger GPs. This preliminary work may be the precursor to a new approach for the recruitment and retention of rural doctors through a greater awareness of personality traits conducive to the rural workforce. Further work may help inform appropriate policies to attract and retain this workforce and be a useful adjunct to the counseling of students interested in rural medicine by providing a better understanding of "what it takes" to be a rural doctor.
Duncan, Lindsay R; Hieftje, Kimberly D; Pendergrass, Tyra M; Sawyer, Benjamin G; Fiellin, Lynn E
2018-02-09
Videogames are becoming increasingly popular to deliver health interventions; however, their role in the primary prevention of cigarette and marijuana use has not yet been evaluated. The purpose of this study was to conduct a preliminary test of the efficacy of a role-playing videogame prototype, smokeSCREEN, aimed at developing knowledge and behavioral skills associated with primary prevention of cigarette and marijuana use. The authors also explored participants' gameplay experience. This study employed a 1-group pretest-posttest design with 25 adolescent boys and girls aged 11 to 14 years (M age = 11.56, SD = 0.77) who had never tried cigarettes or marijuana. Participants played four 1-hour gameplay sessions over a 2-week period. Assessments of knowledge, self-efficacy, attitudes, perceived norms, and intentions related to cigarette and marijuana prevention were collected at baseline and 2-week and 12-week follow-ups. Ratings of gameplay experience were collected after the 2 weeks of gameplay. One-way repeated-measures analyses of variance (ANOVAs) were conducted. Findings are (1) improvements in knowledge for both cigarette (Wilks' λ = 0.62, F(2, 23) = 7.21, P = .004) and marijuana (Wilks' λ = 0.67, F(2, 23) = 5.75, P = .009) use from pre- to post-gameplay that were characterized by large effects; and (2) nonsignificant trends in the expected direction emerged for changes in self-efficacy and perceived norms related to both cigarettes and marijuana that were characterized by medium-large effects. Overall, the players provided positive reports of their experience with the smokeSCREEN videogame prototype. These findings provide preliminary evidence that a videogame has the potential to influence key cognitive and motivational variables and can be an engaging means to deliver a cigarette and marijuana prevention intervention.
Simpson, Susan G.; Pietrabissa, Giada; Rossi, Alessandro; Seychell, Tahnee; Manzoni, Gian Mauro; Munro, Calum; Nesci, Julian B.; Castelnuovo, Gianluca
2018-01-01
Objective: The aim of this study was to examine the psychometric properties and factorial structure of the Schema Mode Inventory for Eating Disorders (SMI-ED) in a disordered eating population. Method: 573 participants with disordered eating patterns as measured by the Eating Disorder Examination Questionnaire (EDE-Q) completed the 190-item adapted version of the Schema Mode Inventory (SMI). The new SMI-ED was developed by clinicians/researchers specializing in the treatment of eating disorders, through combining items from the original SMI with a set of additional questions specifically representative of the eating disorder population. Psychometric testing included Confirmatory Factor Analysis (CFA) and internal consistency (Cronbach's α). Multivariate Analyses of Covariance (MANCOVA) was also run to test statistical differences between the EDE-Q subscales on the SMI-ED modes, while controlling for possible confounding variables. Results: Factorial analysis confirmed an acceptable 16-related-factors solution for the SMI-ED, thus providing preliminary evidence for the adequate validity of the new measure based on internal structure. Concurrent validity was also established through moderate to high correlations on the modes most relevant to eating disorders with EDE-Q subscales. This study represents the first step in creating a psychometrically sound instrument for measuring schema modes in eating disorders, and provides greater insight into the relevant schema modes within this population. Conclusion: This research represents an important preliminary step toward understanding and labeling the schema mode model for this clinical group. Findings from the psychometric evaluation of SMI-ED suggest that this is a useful tool which may further assist in the measurement and conceptualization of schema modes in this population. PMID:29740379
Simpson, Susan G; Pietrabissa, Giada; Rossi, Alessandro; Seychell, Tahnee; Manzoni, Gian Mauro; Munro, Calum; Nesci, Julian B; Castelnuovo, Gianluca
2018-01-01
Objective: The aim of this study was to examine the psychometric properties and factorial structure of the Schema Mode Inventory for Eating Disorders (SMI-ED) in a disordered eating population. Method: 573 participants with disordered eating patterns as measured by the Eating Disorder Examination Questionnaire (EDE-Q) completed the 190-item adapted version of the Schema Mode Inventory (SMI). The new SMI-ED was developed by clinicians/researchers specializing in the treatment of eating disorders, through combining items from the original SMI with a set of additional questions specifically representative of the eating disorder population. Psychometric testing included Confirmatory Factor Analysis (CFA) and internal consistency (Cronbach's α). Multivariate Analyses of Covariance (MANCOVA) was also run to test statistical differences between the EDE-Q subscales on the SMI-ED modes, while controlling for possible confounding variables. Results: Factorial analysis confirmed an acceptable 16-related-factors solution for the SMI-ED, thus providing preliminary evidence for the adequate validity of the new measure based on internal structure. Concurrent validity was also established through moderate to high correlations on the modes most relevant to eating disorders with EDE-Q subscales. This study represents the first step in creating a psychometrically sound instrument for measuring schema modes in eating disorders, and provides greater insight into the relevant schema modes within this population. Conclusion: This research represents an important preliminary step toward understanding and labeling the schema mode model for this clinical group. Findings from the psychometric evaluation of SMI-ED suggest that this is a useful tool which may further assist in the measurement and conceptualization of schema modes in this population.
van Sonsbeek, Gerda R; van der Kolk, Johannes H; van Leeuwen, Johannes P T M; Schaftenaar, Willem
2011-05-01
Hypocalcemia is a well known cause of dystocia in animals, including elephants in captivity. In order to study calcium metabolism in elephants, it is of utmost importance to use properly validated assays, as these might be prone to specific matrix effects in elephant blood. The aim of the current study was to conduct preliminary work for validation of various parameters involved in calcium metabolism in both blood and urine of captive elephants. Basal values of these parameters were compared between Asian elephants (Elephas maximus) and African elephants (Loxodonta africana). Preliminary testing of total calcium, inorganic phosphorus, and creatinine appeared valid for use in plasma and creatinine in urine in both species. Furthermore, measurements of bone alkaline phosphatase and N-terminal telopeptide of type I collagen appeared valid for use in Asian elephants. Mean heparinized plasma ionized calcium concentration and pH were not significantly affected by 3 cycles of freezing and thawing. Storage at 4 °C, room temperature, and 37 °C for 6, 12, and 24 hr did not alter the heparinized plasma ionized calcium concentration in Asian elephants. The following linear regression equation using pH (range: 6.858-7.887) and ionized calcium concentration in heparinized plasma was utilized: iCa(7.4) (mmol/l) = -2.1075 + 0.3130·pH(actual) + 0.8296·iCa(actual) (mmol/l). Mean basal values for pH and plasma in Asian elephant whole blood were 7.40 ± 0.048 and 7.49 ± 0.077, respectively. The urinary specific gravity and creatinine concentrations in both Asian and African elephants were significantly correlated and both were significantly lower in Asian elephants. © 2011 The Author(s)
Bhandari, T R; Dangal, G; Sarma, P S; Kutty, V R
2014-01-01
Women's autonomy is one of the predictors of maternal health care service utilization. This study aimed to construct and validate a scale for measuring women's autonomy with relevance to developing countries. We conducted a study for construction and validation of a scale in Rupandehi and further validated in Kapilvastu districts of Nepal. Initially, we administered a 24-item preliminary scale and finalized a 23-item scale using psychometric tests. After defining the construct of women's autonomy, we pooled 194 items and selected 24 items to develop a preliminary scale. The scale development process followed different steps i.e. definition of construct, generation of items pool, pretesting, analysis of psychometric test and further validation. The new scale was strongly supported by Cronbach's Alpha value (0.84), test-retest Pearson correlation (0.87), average content validity ratio (0.8) and overall agreement- Kappa value of the items (0.83) whereas all values were found satisfactory. From factor analysis, we selected 23 items for the final scale which show good convergent and discriminant validity. From preliminary draft, we removed one item; the remaining 23 items were loaded in five factors. All five factors had single loading items by suppressing absolute coefficient value less than 0.45 and average coefficient was more than 0.60 of each factor. Similarly, the factors and loaded items had good convergent and discriminant validity which further showed strong measurement capacity of the scale. The new scale is a reliable tool for assessing women's autonomy in developing countries. We recommend for further use and validation of the scale for ensuring the measurement capacity.
Velocity Measurements in Nasal Cavities by Means of Stereoscopic Piv - Preliminary Tests
NASA Astrophysics Data System (ADS)
Cozzi, Fabio; Felisati, Giovanni; Quadrio, Maurizio
2017-08-01
The prediction of detailed flow patterns in human nasal cavities using computational fluid dynamics (CFD) can provide essential information on the potential relationship between patient-specific geometrical characteristics of the nasal anatomy and health problems, and ultimately led to improved surgery. The complex flow structure and the intricate geometry of the nasal cavities make achieving such goals a challenge for CFD specialists. The need for experimental data to validate and improve the numerical simulations is particularly crucial. To this aim an experimental set-up based on Stereo PIV and a silicon phantom of nasal cavities have been designed and realized at Politecnico di Milano. This work describes the main features and challenges of the set-up along with some preliminary results.
Brusky, John P.; Tran, Viet Q.; Rieder, Jocelyn M.; Aboseif, Sherif R.
2008-01-01
Purpose. This paper aims at describing the combined penoscrotal and perineal approach for placement of penile prosthesis in cases of severe corporal fibrosis and scarring. Materials and methods. Three patients with extensive corporal fibrosis underwent penile prosthesis placement via combined penoscrotal and perineal approach from 1997 to 2006. Follow-up ranged from 15 to 129 months. Results. All patients underwent successful implantation of semirigid penile prosthesis. There were no short- or long-term complications. Conclusions. Results on combined penoscrotal and perineal approach to penile prosthetic surgery in this preliminary series of patients suggest that it is a safe technique and increases the chance of successful outcome in the surgical management of severe corporal fibrosis. PMID:19043562
Initial operation of high power ICRF system for long pulse in EAST
DOE Office of Scientific and Technical Information (OSTI.GOV)
Qin, C. M., E-mail: chmq@ipp.ac.cn; Zhao, Y. P.; Zhang, X. J.
2015-12-10
The ICRF heating system on EAST upgraded by active cooling aims for long pulse operation. In this paper, the main technical features of the ICRF system are described. One of a major challenges for long pulse operation is RF-edge interactions induced impurity production and heat loading. In EAST, ICRF antenna protections and Faraday screen bars damaged due to LH electron beam are found. Preliminary results for the analysis of the interaction between LHCD and ICRF antenna are discussed. Increase of metal impurities in the plasma during RF pulse and in a larger core radiation are also shown. These RF-edge interactionsmore » at EAST and some preliminary results for the optimizing RF performance will be presented.« less
Fu, Jicheng; Jones, Maria; Jan, Yih-Kuen
2014-01-01
Wheelchair tilt and recline functions are two of the most desirable features for relieving seating pressure to decrease the risk of pressure ulcers. The effective guidance on wheelchair tilt and recline usage is therefore critical to pressure ulcer prevention. The aim of this study was to demonstrate the feasibility of using machine learning techniques to construct an intelligent model to provide personalized guidance to individuals with spinal cord injury (SCI). The motivation stems from the clinical evidence that the requirements of individuals vary greatly and that no universal guidance on tilt and recline usage could possibly satisfy all individuals with SCI. We explored all aspects involved in constructing the intelligent model and proposed approaches tailored to suit the characteristics of this preliminary study, such as the way of modeling research participants, using machine learning techniques to construct the intelligent model, and evaluating the performance of the intelligent model. We further improved the intelligent model's prediction accuracy by developing a two-phase feature selection algorithm to identify important attributes. Experimental results demonstrated that our approaches held the promise: they could effectively construct the intelligent model, evaluate its performance, and refine the participant model so that the intelligent model's prediction accuracy was significantly improved.
Seydell-Greenwald, Anna; Raven, Erika P.; Leaver, Amber M.; Turesky, Ted K.; Rauschecker, Josef P.
2014-01-01
Subjective tinnitus, or “ringing in the ears,” is perceived by 10 to 15 percent of the adult population and causes significant suffering in a subset of patients. While it was originally thought of as a purely auditory phenomenon, there is increasing evidence that the limbic system influences whether and how tinnitus is perceived, far beyond merely determining the patient's emotional reaction to the phantom sound. Based on functional imaging and electrophysiological data, recent articles frame tinnitus as a “network problem” arising from abnormalities in auditory-limbic interactions. Diffusion-weighted magnetic resonance imaging is a noninvasive method for investigating anatomical connections in vivo. It thus has the potential to provide anatomical evidence for the proposed changes in auditory-limbic connectivity. However, the few diffusion imaging studies of tinnitus performed to date have inconsistent results. In the present paper, we briefly summarize the results of previous studies, aiming to reconcile their results. After detailing analysis methods, we then report findings from a new dataset. We conclude that while there is some evidence for tinnitus-related increases in auditory and auditory-limbic connectivity that counteract hearing-loss related decreases in auditory connectivity, these results should be considered preliminary until several technical challenges have been overcome. PMID:25050181
Scasso, Felice; Sprio, Andrea Elio; Canobbio, Luciano; Scanarotti, Chiara; Manini, Giorgio; Berta, Giovanni Nicolao; Bassi, Anna Maria
2017-02-01
Oxidative stress exerts major role in the pathogenesis of side effects of many antineoplastic drugs, including ototoxicity of cisplatin. In particular, increased levels of reactive oxygen species (ROS) represent one of the molecular mechanisms underlying the apoptosis of different types of hearing cells. Antioxidants and ROS scavengers may thus represent potential therapeutic options to prevent platinum-associated ototoxicity. The aim of this preliminary case-control study was to explore the efficacy of a dietary antioxidant supplement, in order to hamper the occurrences of ototoxicity in patients undergoing cisplatin chemotherapy. As results, a significant protection against cochlear toxic damage was demonstrated in patients who took the antioxidant supplement, which furthermore prevented the occurrence of hearing disorders and tinnitus. These clinical evidences were corroborated by the oxidative status of patients. After cisplatin chemotherapy, the plasma derivatives of reactive oxygen metabolites (d-ROMs) content rapidly increased in control patients, but it was maintained in those under dietary supplementation, likely because of a higher anti-ROMs potential. Indeed, an increment in rapid anti-ROMs was detected in supplemented patients, though no differences were highlighted in terms of slow anti-ROMs. In conclusion, in this preliminary report we demonstrated the feasibility of a dietary antioxidant supplementation in order to prevent the cisplatin induced hearing damage.
Stern, Robert A; Tripodis, Yorghos; Baugh, Christine M; Fritts, Nathan G; Martin, Brett M; Chaisson, Christine; Cantu, Robert C; Joyce, James A; Shah, Sahil; Ikezu, Tsuneya; Zhang, Jing; Gercel-Taylor, Cicek; Taylor, Douglas D
2016-01-01
Chronic traumatic encephalopathy (CTE) is a tauopathy associated with prior exposure to repetitive head impacts, such as those incurred through American football and other collision sports. Diagnosis is made through neuropathological examination. Many of the clinical features of CTE are common in the general population, with and without a history of head impact exposure, making clinical diagnosis difficult. As is now common in the diagnosis of other neurodegenerative disorders, such as Alzheimer's disease, there is a need for methods to diagnose CTE during life through objective biomarkers. The aim of this study was to examine tau-positive exosomes in plasma as a potential CTE biomarker. Subjects were 78 former National Football League (NFL) players and 16 controls. Extracellular vesicles were isolated from plasma. Fluorescent nanoparticle tracking analysis was used to determine the number of vesicles staining positive for tau. The NFL group had higher exosomal tau than the control group (p < 0.0001). Exosomal tau discriminated between the groups, with 82% sensitivity, 100% specificity, 100% positive predictive value, and 53% negative predictive value. Within the NFL group, higher exosomal tau was associated with worse performance on tests of memory (p = 0.0126) and psychomotor speed (p = 0.0093). These preliminary findings suggest that exosomal tau in plasma may be an accurate, noninvasive CTE biomarker.
Sewage sludge drying by energy recovery from OFMSW composting: preliminary feasibility evaluation.
Rada, Elena Cristina; Ragazzi, Marco; Villotti, Stefano; Torretta, Vincenzo
2014-05-01
In this paper an original energy recovery method from composting is analyzed. The integrated system exploits the heat available from the aerobic biochemical process in order to support the drying of sewage sludge, using a specific solar greenhouse. The aim is to tackle the problem of organic waste treatment, with specific regard to food waste. This is done by optimizing the energy consumption of the aerobic process of composting, using the heat produced to solve a second important waste management problem such as the sewage waste treatment. Energy and mass balances are presented in a preliminary feasibility study. Referring to a composting plant with a capacity of 15,000 t/y of food waste, the estimation of the power from recovered heat for the entire plant resulted about 42 kW. The results demonstrated that the energy recoverable can cover part of the heat necessary for the treatment of sludge generated by the population served by the composting plant (in terms of food waste and green waste collection). The addition of a renewable source such as solar energy could cover the residual energy demand. The approach is presented in detail in order for it to be replicated in other case studies or at full scale applications. Copyright © 2014 Elsevier Ltd. All rights reserved.
Nolfe, Giovanni; Petrella, Claudio; Triassi, Maria; Zontini, Gemma; Uttieri, Simona; Pagliaro, Alessia; Blasi, Francesco; Cappuccio, Antonella; Nolfe, Giuseppe
2013-01-01
The aim of this study is to produce preliminary data about the validation of the "Naples-Questionnaire of Distress at Work" (nQ.DW). This inventory is a new assessment tool in order to evaluate the distress perceived in the working environment by means of the differentiation of the conditions linked to the mobbing from which related to organizational disfunction. The nQ-DW also measures the bio-psycho-social global effects of these two phenomena. The questionnaire has been administered to workers suffering of a psychopathological disturbance related to work distress and to a control group matched for the sociodemographic and working variables. The statistical analysis demonstrated a significant validity and reliability. The degree of internal coherence was satisfactory. The ROC curves allow the determination of a threshold value which allows to separate the workers subjected to mobbing and/or organizational stress from control-workers with an optimal reliability degree. The values of the area under the ROC curves show that the inventory has a high discriminating capacity. Future studies, based on a greater sample size, will be oriented to the analysis of the questionnaire by means of multivariate techniques like the factorial analysis.
Ultrasonographic analysis in vitro of parietal thickness of lower limb varicose veins.
Bruschi, E; Como, G; Zuiani, C; Segatto, E; Rocco, M; Biasi, G; Bazzocchi, M
2006-09-01
The aim of this study was to evaluate the ability of ultrasound (US) to measure the parietal thickness of varicose veins. In a blind in vitro analysis, 28 great saphenous veins, obtained after stripping surgery from 28 patients with chronic venous insufficiency, were examined with a digital US scanner ATL-HDI5000, linear 5-1 to 2-MHz broadband probe, compound imaging technique and analogic-digital zooming. We obtained one to three progressive measurements for each vein wall (total 67 parietal thicknesses). The samples, fixed in formalin, were sent to the pathology laboratory: sections were obtained at the same level of the sonographic planes, and images were obtained by digital camera mounted on an optical microscope. Measurements obtained at histology were considered as the gold standard. K-statistic was applied to compare sonographic and histologic measurements. Considering only the hypoechoic wall portion, 29/29 (100%) diagnoses of hypotrophy (K=0.91), 19/22 (86%) diagnoses of normotrophy (K=0,47) and 12/16 (75%) diagnoses of hypertrophy (K=0.7) were obtained by sonography. In our preliminary experience, the in vitro study of varicose veins allows precise, at least morphological, detection of hypotrophic walls. If these preliminary data are confirmed in vivo, sonography could be used to discriminate patients eligible for conservative treatment instead of surgery.
Catroppa, Cathy; Stone, Kate; Hearps, Stephen J C; Soo, Cheryl; Anderson, Vicki; Rosema, Stefanie
2015-01-01
Impairments in attention and memory are common sequelae following paediatric acquired brain injury (ABI). While it has been established that such impairments are long-term and, therefore, affect quality-of-life, there is a scarcity of evidence-based interventions to treat these difficulties. The current study aimed to pilot the efficacy of the Amsterdam Memory and Attention Training for Children (Amat-c: English version) using both neuropsychological and ecologically sensitive measures. It was expected that children with attention and memory difficulties post-ABI would show improved performance post-intervention on cognitive and ecological measures, with maintenance at 6 months post-intervention. Ten children with an ABI, between the ages of 8-13 years at the time of recruitment were identified through audits of presentations to a metropolitan paediatric hospital. Each child underwent screening, the 18 week intervention programme, pre-intervention, immediate and 6 month post-intervention assessments. Findings supported the hypothesis that children would show post-intervention (immediate and 6 month) improvement in areas of attention and memory, with generalization to everyday life. Preliminary results provide support for the efficacy of the Amat-c post-childhood ABI. A larger study is needed to confirm these findings, as a reduction in attention and memory difficulties will enhance everyday functioning.
Di Tecco, Cristina; Ronchetti, Matteo; Ghelli, Monica; Russo, Simone; Persechino, Benedetta
2015-01-01
Studies on Intervention Process Evaluation are attracting growing attention in the literature on interventions linked to stress and the wellbeing of workers. There is evidence that some elements relating to the process and content of an intervention may have a decisive role in implementing it by facilitating or hindering the effectiveness of the results. This study aimed to provide a process evaluation on interventions to assess and manage risks related to work-related stress using a methodological path offered by INAIL. The final sample is composed of 124 companies participating to an interview on aspects relating to each phase of the INAIL methodological path put in place to implement the intervention. INAIL methodology has been defined as useful in the process of assessing and managing the risks related to work-related stress. Some factors related to the process (e.g., implementation of a preliminary phase, workers' involvement, and use of external consultants) showed a role in significant differences that emerged in the levels of risk, particularly in relation to findings from the preliminary assessment. Main findings provide information on the key aspects of process and content that are useful in implementing an intervention for assessing and managing risks related to work-related stress. PMID:26504788
Ardigò, M; Agozzino, M; Amorosi, B; Moscarella, E; Cota, C; de Abreu, L; Berardesca, E
2014-05-01
Bullous pemphigoid is an autoimmune disease affecting prevalently the elder. In vivo reflectance confocal microscopy is a non-invasive technique for real-time imaging of the skin with cellular-level resolution. No previous data has been reported about confocal microscopy of bullous pemphigoid. Aim of this preliminary study is the evaluation of the potential of in vivo reflectance confocal microscopy for real-time, microscopical confirmation of clinical bullous pemphigoid diagnosis. A total of nine lesions from patients affected by pemphigoid underwent in vivo reflectance confocal microscopy before histological examination. In our preliminary study, confocal microscopy showed high grade of correspondence to histopathology. In particular, presence of sub-epidermal cleft and variable amount of oedema of the upper dermis associated with inflammatory cells infiltration were seen as prevalent confocal features in the bullous lesions considered. Differently, in urticarial lesions, no specific features could be appreciated at confocal analysis beside the presence of signs of spongiosis and perivascular inflammation. Confocal microscopy seems to be useful for in vivo, microscopical confirmation of the clinical suspect of bullous pemphigoid and for biopsy site selection in urticarial lesions to obtain a more significant specimen for histopathological examination. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
NASA Astrophysics Data System (ADS)
Suci, Windhu Griyasti; Margono, Kaavessina, Mujtahid
2018-02-01
Bioethanol has been well acknowledged to be developed as a biofuel and can be derived from renewable resources. Currently, the utilization of bioethanol as a fuel is more expensive than that of gasoline due to the high production cost. Researchers from industrial and academia have been doing some efforts to reduce it, namely: energy efficiency, exploring many potential renewable resources, increasing fermentation productivity, etc. We propose a novel immobilized Saccharomyces cerevisiae trapped in grafted bioflocculant. The flocculant was developed from polyacrylamide chains grafted into modified starches. This research aims to preliminary performance study of S. cerevisiae immobilized using our new developed method. The bioflocculant solution with the various concentration of 1%, 2%, and 2.5% v/v was dropped into 90 ml of developed inoculum to get flocs which would be used as a starter in fermentation process. The fermentation process was carried out in a shaken flask at 30oC and 150 rpm for 72 hours. The best result was obtained in the sample of 2.5% bioflocculant fraction, i.e. bioethanol 9.25% and enhanced productivity 3.6 times of free cell. These results indicate that flocculation method is a way of immobilizing yeast that needs to be further investigated.
Preliminary evidence for a unique role of disgust-based conditioning in posttraumatic stress.
Badour, Christal L; Feldner, Matthew T; Blumenthal, Heidemarie; Knapp, Ashley
2013-04-01
Independent lines of evidence have linked posttraumatic stress symptomatology to both peritraumatic disgust (i.e., disgust experienced during a traumatic event) and posttraumatic disgust reactivity in response to traumatic event cues among individuals exposed to traumatic events. Much of this work suggests disgust, defined as a rejection/revulsion response aimed at distancing oneself from a potential source of contamination, may be important in understanding the nature of posttraumatic stress reactions even after accounting for the more frequently studied affective states of fear and anxiety. The current investigation provided a preliminary test of a model of disgust in posttraumatic stress among a sample of 54 community-recruited women with a history sexual victimization. Both peritraumatic disgust (r = .31) and posttraumatic disgust reactivity (r = .42) in response to an idiographic traumatic event script were significantly associated with posttraumatic stress symptom severity. After accounting for variability-associated peritraumatic fear and posttraumatic anxious reactivity, an indirect effect of peritraumatic disgust through posttraumatic disgust reactivity also was found, suggesting that one mechanism through which peritraumatic disgust relates to posttraumatic stress is through its relation with increased posttraumatic disgust reactivity. These findings highlight the importance of further elucidating the nature of disgust in relation to traumatic events and subsequent posttraumatic stress reactions. Copyright © 2013 International Society for Traumatic Stress Studies.
Gonçalves, Luciana Kneib; da Silva, Ivy Reichert Vital; Cechinel, Laura Reck; Frusciante, Marina Rocha; de Mello, Alexandre Silva; Elsner, Viviane Rostirola; Funchal, Claudia; Dani, Caroline
2017-11-20
This study aimed to investigate the impact of maternal consumption of a hyperlipid diet and grape juice on global histone H4 acetylation levels in the offsprinǵs hippocampus at different stages of development. During pregnancy and lactation of offspring, dams were divided into 4 groups: control diet (CD), high-fat diet (HFD), control diet and purple grape juice (PGJCD) and purple grape juice and high-fat diet (PGJHFD). Male Wistar rats were euthanized at 21days of age (PN21, adolescents) and at 50days of age (PN50, adults). The maternal consumption of grape juice increased global histone H4 acetylation levels in hippocampus of adolescents pups (PN21), an indicative of enhanced transcriptional activity and increased gene expression. On the other hand, the maternal high-fat diet diminished significantly this epigenetic marker in the adult phase (PN50), suggesting gene silencing. These preliminary findings demonstrated that the maternal choices are able to induce changes on histone H4 acetylation status in hippocampus of the offspring, which may modulate the expression of specific genes. Interestingly, this response occurs in an age and stimuli-dependent manner and strongly reinforce the importance of maternal choices during gestation. Copyright © 2017 Elsevier B.V. All rights reserved.
Di Tecco, Cristina; Ronchetti, Matteo; Ghelli, Monica; Russo, Simone; Persechino, Benedetta; Iavicoli, Sergio
2015-01-01
Studies on Intervention Process Evaluation are attracting growing attention in the literature on interventions linked to stress and the wellbeing of workers. There is evidence that some elements relating to the process and content of an intervention may have a decisive role in implementing it by facilitating or hindering the effectiveness of the results. This study aimed to provide a process evaluation on interventions to assess and manage risks related to work-related stress using a methodological path offered by INAIL. The final sample is composed of 124 companies participating to an interview on aspects relating to each phase of the INAIL methodological path put in place to implement the intervention. INAIL methodology has been defined as useful in the process of assessing and managing the risks related to work-related stress. Some factors related to the process (e.g., implementation of a preliminary phase, workers' involvement, and use of external consultants) showed a role in significant differences that emerged in the levels of risk, particularly in relation to findings from the preliminary assessment. Main findings provide information on the key aspects of process and content that are useful in implementing an intervention for assessing and managing risks related to work-related stress.
Effects of ripening on rheological properties of avocado pulp (Persea americana mill. Cv. Hass)
NASA Astrophysics Data System (ADS)
Osorio, F.; Roman, A.; Ortiz, J.
2015-04-01
Avocado (Persea americana Mill) Hass variety is the most planted in Chile with a greater trade prospect. The aim of this study was to investigate the effect of maturity on rheological properties of Chilean Avocado Hass pulp. Fresh unripe avocados were washed and peeled, cut and stored at 3 different times; a portion was treated at 5°C and the other was treated at 20°C until it reached 2 lb puncture pressure. During maturation changes would develop due to temperature and time, with internal cellular structure changes. Preliminary results of the rheological characteristics of avocado puree show a Bingham plastic behavior.
Borgna, F; Ballan, M; Corradetti, S; Vettorato, E; Monetti, A; Rossignoli, M; Manzolaro, M; Scarpa, D; Mazzi, U; Realdon, N; Andrighetto, A
2017-09-01
Radiopharmaceuticals represent a fundamental tool for nuclear medicine procedures, both for diagnostic and therapeutic purposes. The present work aims to explore the Isotope Separation On-Line (ISOL) technique for the production of carrier-free radionuclides for nuclear medicine at SPES, a nuclear physics facility under construction at INFN-LNL. Stable ion beams of strontium, yttrium and iodine were produced using the SPES test bench (Front-End) to simulate the production of 89 Sr, 90 Y, 125 I and 131 I and collected with good efficiency on suitable targets. Copyright © 2017 Elsevier Ltd. All rights reserved.
Investigation of the Effects of MIR-FELIrradiation on the Photoluminescence of Titanium Dioxides
NASA Astrophysics Data System (ADS)
Sonobe, T.; Bakr, M.; Yoshida, K.; Higashimura, K.; Kinjo, R.; Hachiya, K.; Kii, T.; Masuda, K.; Ohgaki, H.
2010-02-01
A mid-infrared free electron laser (MIR-FEL: 5 μm-20 μm) facility (KU-FEL: Kyoto University Free Electron Laser) has been constructed in Institute of Advanced Energy Kyoto University, and first laser saturation at 13.2 μm was achieved in May 2008. Currently, we have started to develop the application of MIR-FEL in the field of energy and material science. This study aimed at investigating the feasibility for the development of new evaluation technique of electron-phonon interaction in metal oxides by MIR-FEL. A preliminary result of electrical and optical properties of titanium dioxides was presented.
NASA Astrophysics Data System (ADS)
Fauziah, A.; Putri, R. I. I.; Zulkardi; Somakim
2017-12-01
This article aimed to report the perceptions of the students of primary school education to PMRI. PMRI or Realistic Mathematics Education (RME) in Indonesian version is one of the promising mathematics learning innovations developed in Indonesia. The research method consisted of three steps, namely preliminary, teaching experiment, and retrospective Analysis. The participants were six students of the primary school teacher education. In the second phase, the participants took an PMRI lesson. Then, they filled in the perception questionnaire (open and closed). The results of the study showed that the participants agreed that learning by realistic mathematics education principles helped them understand the topic.
Home Exercise in a Social Context: Real-Time Experience Sharing Using Avatars
NASA Astrophysics Data System (ADS)
Aghajan, Yasmin; Lacroix, Joyca; Cui, Jingyu; van Halteren, Aart; Aghajan, Hamid
This paper reports on the design of a vision-based exercise monitoring system. The system aims to promote well-being by making exercise sessions enjoyable experiences, either through real-time interaction and instructions proposed to the user, or via experience sharing or group gaming with peers in a virtual community. The use of avatars is explored as means of representation of the user’s exercise movements or appearance, and the system employs user-centric approaches in visual processing, behavior modeling via history data accumulation, and user feedback to learn the preferences. A preliminary survey study has been conducted to explore the avatar preferences in two user groups.
Weigel, Angelika; Gumz, Antje; Kästner, Denise; Romer, Georg; Wegscheider, Karl; Löwe, Bernd
2015-07-01
The "Health care network anorexia and bulimia nervosa", a subproject of psychenet - the Hamburg network for mental health - aims to decrease the incidence of eating disorders as well as the risk for chronic illness courses. One focal project, therefore, evaluates a school-based prevention manual in a randomized controlled trial. The other one examines the impact of a systemic public health intervention on early treatment initiation in anorexia nervosa. The present article provides an overview about study design and interventions in both focal projects as well as preliminary results. © Georg Thieme Verlag KG Stuttgart · New York.
MicroRNAs in urine are not biomarkers of multiple myeloma.
Sedlaříková, Lenka; Bešše, Lenka; Novosadová, Soňa; Kubaczková, Veronika; Radová, Lenka; Staník, Michal; Krejčí, Marta; Hájek, Roman; Ševčíková, Sabina
2015-09-23
In this study, we aimed to identify microRNA from urine of multiple myeloma patients that could serve as a biomarker for the disease. Analysis of urine samples was performed using Serum/Plasma Focus PCR MicroRNA Panel (Exiqon) and verified using individual TaqMan miRNA assays for qPCR. We found 20 deregulated microRNA (p < 0.05); for further validation, we chose 8 of them. Nevertheless, only differences in expression levels of miR-22-3p remained close to statistical significance. Our preliminary results did not confirm urine microRNA as a potential biomarker for multiple myeloma.
Leadership Styles of Oxford House Officers
Komer, Anne C; Jason, Leonard A; Harvey, Ronald; Olson, Brad
2015-01-01
Oxford House recovery homes are unusual compared to most recovery homes in that they function entirely without the use of staff; instead members are elected to officer positions. The aim of this study was to perform preliminary analysis of the types of leadership styles utilized by members of oxford house. Twentynine house residents of five Oxford Houses were asked to rate their own leadership styles using the leader behavior description questionnaire and the multifactor leader questionnaire. Results showed that participants were more likely to use person-oriented behaviors above task-oriented actions. Transformational leadership was associated with higher outcomes than Transactional leadership. Implications for future research are discussed. PMID:26380329
Leadership Styles of Oxford House Officers.
Komer, Anne C; Jason, Leonard A; Harvey, Ronald; Olson, Brad
Oxford House recovery homes are unusual compared to most recovery homes in that they function entirely without the use of staff; instead members are elected to officer positions. The aim of this study was to perform preliminary analysis of the types of leadership styles utilized by members of oxford house. Twentynine house residents of five Oxford Houses were asked to rate their own leadership styles using the leader behavior description questionnaire and the multifactor leader questionnaire. Results showed that participants were more likely to use person-oriented behaviors above task-oriented actions. Transformational leadership was associated with higher outcomes than Transactional leadership. Implications for future research are discussed.
Removal of uranyl ions by p-hexasulfonated calyx[6]arene acid
NASA Astrophysics Data System (ADS)
Popescu (Hoştuc), Ioana-Carmen; Petru, Filip; Humelnicu, Ionel; Mateescu, Marina; Militaru, Ecaterina; Humelnicu, Doina
2014-10-01
Radioactive pollution is a significant threat for the people's health. Therefore highly effective radioactive decontamination methods are required. Ion exchange, biotechnologies and phytoremediation in constructed wetlands have been used as radioactive decontamination technologies for uranium contaminated soil and water remediation. Recently, beside those classical methods the calix[n]arenic derivatives' utilization as radioactive decontaminators has jogged attention. The present work aims to present the preliminary research results of uranyl ion sorption studies on the p-hexasulfonated calyx[6]arenic acid. The effect of temperature, contact time, sorbent amount and uranyl concentration variation on sorption efficiency was investigated. Isotherm models revealed that the sorption process fit better Langmuir isotherm.
Developing a manual for strengthening mental health nurses' clinical supervision.
Buus, Niels; Cassedy, Paul; Gonge, Henrik
2013-05-01
In this article, we report findings from a study aimed at developing the content and implementation of a manual for a research-based intervention on clinical supervision of mental health nursing staff. The intervention was designed to strengthen already existing supervision practices through educational preparation for supervision and systematic reflection on supervision. The intervention consists of three sessions and was implemented on two groups of mental health hospital staff. We present an outline of the manual and explain how the trial sessions made us adjust the preliminary manual. The effects of implementing the manual will subsequently be analysed in an independent randomised controlled trial.
Archaeoastronomical Information in the Study of Cremation Necropolis: Preliminary Study
NASA Astrophysics Data System (ADS)
Mejuto, J.; Cerde, M. L.; Rodríguez, C.
2009-08-01
This work remarks the significance that archaeoastronomical studies have for archaeological research. These studies provide us data about the perception that ancient societies had about astronomical events and how these facts were added to their religious and ideological world. Thus, archaeoastronomy become a valuable source of information when aimed to solve any question involving the ancient societies. We take as reference in this work some of the Late Bronze Age{'}s cremation necropolis, representatives of usually called Urnfields, to check if their design can be related to some celestial phenomena: Can Bech de Baix (Gerona), Can Pitieu-Can Roqueta(Barcelona), Molá (Tarragona), Can Missert (Tarragona), Les Obagues (Tarragona), La Colomina (Lleida) and La Torraza (Navarra). Likewise a new standard in archaeological excavations maps is proposed. This will allow getting the information more available and improving further studies.
NASA Astrophysics Data System (ADS)
Nugraheni, L. R.; Niasari, S. W.; Nukman, M.
2018-04-01
Geothermal manifestations located in the Tiris, Mount Lamongan, Probolinggo, consist of warm springs. These warm springs have temperature from 35° until 45°C. Tiris fault has NW-SE dominant orientation, similar to some lineaments of maars and cinder cones around Mount Lamongan. The Mount Lamongan geothermal area is situated between Bromo and Argapura volcanoes. This study aims to map the geo-electrical and geological strikes in the study area. Phase tensor analysis has been performed in this study to determine geo-electrical strike of study area. Geological field campaign has been conducted to measure geological strikes. Then, orientation of geo-electrical strike was compared to geological strike. The result presents that the regional geological strike of study area is NW-SE while the orientation of geo-electrical strike is N-S.
Boots, Lizzy Mm; de Vugt, Marjolein E; Withagen, Hanneke Ej; Kempen, Gertrudis Ijm; Verhey, Frans Rj
2016-03-01
People with dementia increasingly depend on informal caregivers. Internet-based self-management interventions hold considerable promise for meeting the educational and support needs of early stage dementia caregivers (EDCs) at a reduced cost. This study aimed to (1) develop an online self-management program for EDC to increase self-efficacy and goal attainment, and (2) evaluate the program's feasibility and report preliminary data on effectiveness. Based on the Medical Research Council (MRC) framework for the development and evaluation of complex interventions, a stepwise approach was adopted to explore potential user needs and develop and validate the content by means of (1) focus group discussions with dementia caregivers (N=28), (2) interviews with dementia care professionals (N=11), and (3) individual think-aloud usability tests with EDC (N=2) and experts (N=2). A pilot evaluation was conducted with EDC (N=17) to test the feasibility and establish preliminary effects. Self-report measures of feasibility were completed after the completion of intervention. Self-efficacy and goal attainment were evaluated before and after the intervention. The different steps provided useful information about the needs of potential users regarding the content and delivery of the program. This resulted in the newly developed "Partner in Balance" program. At the start, system failures resulted in a high noncompleter rate (7/17, 41%), but at the end, an acceptable feasibility score of 209 (range 54-234) was found. The convenience of completing the program at home, the tailored content, and the guidance (face-to-face and online) were appraised positively. Preliminary effects on caregiver self-efficacy (P<.05) and goal attainment (T>50) were promising. Adaptations were made to the program to limit the amount of system failures and prevent high noncompleter rates. As recommended by the MRC framework, confirming the feasibility and preliminary effectiveness is a valuable step toward examining the effectiveness of this newly developed intervention. Dutch Trial Register (NTR): NTR4217; http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4217 (Archived by WebCite at http://www.webcitation.org/6f6B8lvRP).
Subionospheric VLF Propagation Modelling During a solar flares
NASA Astrophysics Data System (ADS)
Akel, A. F.
2013-05-01
This work aims to present a preliminary study of the behavior of the lower ionosphere under transient regimes of ionization through the technique of wave propagation of VLF (Very Low Frequency). For this, we characterized the lower ionosphere by two traditional (wait) parameters H' and β which are found by VLF radio modelling using the computational code of subionospheric radio propagation LWPC(Long Wave Propagation Capability). The main effects and behaviors investigated in this study was due to a solar flare 2M class near solar minimum at 03/25/2008. We changed Solar zenith angle dependence of the ionospheric parameters H' and β for diurnal time by a polynomial equation. For this study we used the available data the South America VLF Network (SAVNET) and show the results between modeling and data
ERIC Educational Resources Information Center
Gangji, Nazneen; Pascoe, Michelle; Smouse, Mantoa
2015-01-01
Background: Swahili is widely spoken in East Africa, but to date there are no culturally and linguistically appropriate materials available for speech-language therapists working in the region. The challenges are further exacerbated by the limited research available on the typical acquisition of Swahili phonology. Aim: To describe the speech…
ERIC Educational Resources Information Center
Dean, Aftab; Gibbs, Paul
2015-01-01
Purpose: This paper aims to investigate the purpose of the complex open system of higher education and to explore this transformative experience as personal flourishing, where students come to terms with a way of being, matching their potentiality with their agency and leading to profound happiness. There is influential, but not uncontested…
ERIC Educational Resources Information Center
Kusumaningrum, Indrati; Hidayat, Hendra; Ganefri; Anori, Sartika; Dewy, Mega Silfia
2016-01-01
This article describes the development of a business plan by using production-based learning approach. In addition, this development also aims to maximize learning outcomes in vocational education. Preliminary analysis of curriculum and learning and the needs of the market and society become the basic for business plan development. To produce a…
Impact of Knowledge Management on Learning Organization Practices in India: An Exploratory Analysis
ERIC Educational Resources Information Center
Chawla, Deepak; Joshi, Himanshu
2011-01-01
Purpose: This paper aims to report the preliminary findings of the difference in learning organization (LO) practices across industries. It also reports the impact of knowledge management (KM) dimensions on LO and whether this impact is different across manufacturing, IT and IT-enabled services (ITES) and power generation and distribution in…
ERIC Educational Resources Information Center
Hodgson, Sarah; Papatheodorou, Theodora; James, Mary
2014-01-01
The article aims to discuss preliminary findings from a participatory monitoring and evaluation (M&E) framework, used in a community-based early childhood development (ECD) programme in KwaZulu-Natal South Africa, and their implications for leadership and management. The purposes of the M&E were for LETCEE, the implementing organization,…
Climatizing the Home Minicourse, Career Oriented Pre-Technical Physics. Preliminary Edition.
ERIC Educational Resources Information Center
Bullock, Bob; And Others
This minicourse was prepared for use with secondary physics students in the Dallas Independent School District and is one option in a physics program which provides for the selection of topics on the basis of student career needs and interests. This minicourse was aimed at providing students with a knowledge of the physics factors that determine…
ERIC Educational Resources Information Center
Bryson, Susan E.; Koegel, Lynn K.; Koegel, Robert L.; Openden, Daniel; Smith, Isabel M.; Nefdt, Nicolette
2007-01-01
This paper describes a collaborative effort aimed at province-wide dissemination and implementation of pivotal response treatment (PRT) for young children with autism spectrum disorder (ASD) in Nova Scotia, Canada. Three critical components of the associated training model are described: (1) direct training of treatment teams (parents, one-to-one…
Automobile Ignition System Minicourse, Career Oriented Pre-Technical Physics. Preliminary Edition.
ERIC Educational Resources Information Center
Bullock, Bob; And Others
This minicourse was prepared for use with secondary physics students in the Dallas Independent School District and is one option in a physics program which provides for the selection of topics on the basis of student career needs and interests. This minicourse was aimed at providing the student with a basic understanding of the construction and…
Some first experiments on the photometric calibration of Schmidt plates against the Tycho catalogue
NASA Technical Reports Server (NTRS)
Morrison, J. E.; Lasker, B.; McLean, B.; Bucciarelli, B.; Spagna, A.; Zacchei, A.
1997-01-01
Preliminary work carried out with the aim of reducing the Guide Star Catalog (GSC2) measurements of the Palomar 2 plates with the Tycho catalog for a 625 sq deg test field centered on the North Galactic Pole, is reported on and the results are presented. The emphasis was on the photometric calibrations.
ERIC Educational Resources Information Center
Castro, Diego; Rodríguez-Gómez, David; Gairín, Joaquín
2017-01-01
Access to higher education has increased substantially in Latin America, but inequalities in access to and completion of higher education still remain. In this regard, identifying vulnerable groups and exclusion factors is a priority in Latin America's university systems. The aim of this article is to understand in depth governing board…
Unraveling the Mystery of Exozodiacal Dust
NASA Astrophysics Data System (ADS)
Ertel, S.; Augereau, J.-C.; Thébault, P.; Absil, O.; Bonsor, A.; Defrère, D.; Kral, Q.; Le Bouquin, J.-B.; Lebreton, J.; Coudé du Foresto, V.
2014-01-01
Exozodiacal dust clouds are thought to be the extrasolar analogs of the Solar System's zodiacal dust. Studying these systems provides insights in the architecture of the innermost regions of planetary systems, including the Habitable Zone. Furthermore, the mere presence of the dust may result in major obstacles for direct imaging of earth-like planets. Our EXOZODI project aims to detect and study exozodiacal dust and to explain its origin. We are carrying out the first large, near-infrared interferometric survey in the northern (CHARA/FLUOR) and southern (VLTI/PIONIER) hemispheres. Preliminary results suggest a detection rate of up to 30% around A to K type stars and interesting trends with spectral type and age. We focus here on presenting the observational work carried out by our team.
HLA-B27 allele frequency in Sri Lankan patients with spondyloarthritides.
Kidnapillai, S; Sirisena, N D; Dissanayake, V H
2016-06-01
This preliminary study aims to describe the HLA-B27 allele frequency in Sri Lankan patients with spondyloarthritides (SA). An anonymised database of 373 Sri Lankan patients with SA referred for HLA-B27 testing was retrospectively analysed. Eighty five (22.8%) patients were positive for the HLA-B27 allele. A male preponderance was observed among the positives. The HLA-B27 allele frequency in this sample of patients with SA was relatively low compared to published studies in other populations. Further research is needed to identify the predominant subtypes of the allele to determine which subtypes are the most prevalent in a larger sample of Sri Lankan patients with SA, and to define their association with the specific types of SA.
[Effectiveness of dog-assisted therapy in the elderly. A preliminary study].
Folch, Anabel; Torrente, Margarita; Heredia, Luis; Vicens, Paloma
2016-01-01
Animal-assisted therapy is increasingly present in several educational and health areas. The aim of this study is to assess the effectiveness of such interventions in the elderly population living in residential settings. A 12-week dog-assisted intervention program was designed, with 16 participants from a nursing home divided into an experimental group and a control group. Several physical and psychological variables were assessed before and after the intervention. While there were no significant differences in the control group, the experimental group improved significantly after participating in the program. The results support the hypothesis that animal-assisted interventions may be beneficial for residents in elderly care homes. Copyright © 2015 SEGG. Publicado por Elsevier España, S.L.U. All rights reserved.
A neutron camera system for MAST.
Cecconello, M; Turnyanskiy, M; Conroy, S; Ericsson, G; Ronchi, E; Sangaroon, S; Akers, R; Fitzgerald, I; Cullen, A; Weiszflog, M
2010-10-01
A prototype neutron camera has been developed and installed at MAST as part of a feasibility study for a multichord neutron camera system with the aim to measure the spatial and time resolved 2.45 MeV neutron emissivity profile. Liquid scintillators coupled to a fast digitizer are used for neutron/gamma ray digital pulse shape discrimination. The preliminary results obtained clearly show the capability of this diagnostic to measure neutron emissivity profiles with sufficient time resolution to study the effect of fast ion loss and redistribution due to magnetohydrodynamic activity. A minimum time resolution of 2 ms has been achieved with a modest 1.5 MW of neutral beam injection heating with a measured neutron count rate of a few 100 kHz.
The spectral energy distributions of the entire Herschel Reference Survey
NASA Astrophysics Data System (ADS)
Ciesla, Laure
2012-08-01
We present the spectral energy distributions (SED) of the 323 galaxies of the Herschel Reference Survey. In order to provide templates for nearby galaxies calibrated on physical parameters, we computed mean SEDs per bin of morphological types and stellar masses. They will be very useful to study more distant galaxies and their evolution with redshift. This preliminary work aims to study how the most commonly used libraries (Chary & Elbaz 2001, Dale & Helou 2002 and Draine & Li 2007) reproduce the far-infrared emission of galaxies. First results show that they reproduce well the far-infrared part of mean SEDs. For single galaxies the Draine & Li (2007) models seem to reproduce very well the far-infrared emission, as does the Dale & Helou (2002).