Communicating shared knowledge in infancy.

PubMed

Egyed, Katalin; Király, Ildikó; Gergely, György

2013-07-01

Object-directed emotion expressions provide two types of information: They can convey the expressers' person-specific subjective disposition toward objects, or they can be used communicatively as referential symbolic devices to convey culturally shared valence-related knowledge about referents that can be generalized to other individuals. By presenting object-directed emotion expressions in communicative versus noncommunicative contexts, we demonstrated that 18-month-olds can flexibly assign either a person-centered interpretation or an object-centered interpretation to referential emotion displays. When addressed by ostensive signals of communication, infants generalized their object-centered interpretation of the emotion display to other individuals as well, whereas in the noncommunicative emotion-expression context, they attributed to the emoting agent a person-specific subjective dispositional attitude without generalizing this attribution as relevant to other individuals. The findings indicate that, as proposed by natural pedagogy theory, infants are prepared to learn shared cultural knowledge from nonverbal communicative demonstrations addressed to them at a remarkably early age.

A philosophical examination of Mead's pragmatist constructivism as a referent for adult science education

NASA Astrophysics Data System (ADS)

Furbish, Dean Russel

The purpose of this study is to examine pragmatist constructivism as a science education referent for adult learners. Specifically, this study seeks to determine whether George Herbert Mead's doctrine, which conflates pragmatist learning theory and philosophy of natural science, might facilitate (a) scientific concept acquisition, (b) learning scientific methods, and (c) preparation of learners for careers in science and science-related areas. A philosophical examination of Mead's doctrine in light of these three criteria has determined that pragmatist constructivism is not a viable science education referent for adult learners. Mead's pragmatist constructivism does not portray scientific knowledge or scientific methods as they are understood by practicing scientists themselves, that is, according to scientific realism. Thus, employment of pragmatist constructivism does not adequately prepare future practitioners for careers in science-related areas. Mead's metaphysics does not allow him to commit to the existence of the unobservable objects of science such as molecular cellulose or mosquito-borne malarial parasites. Mead's anti-realist metaphysics also affects his conception of scientific methods. Because Mead does not commit existentially to the unobservable objects of realist science, Mead's science does not seek to determine what causal role if any the hypothetical objects that scientists routinely posit while theorizing might play in observable phenomena. Instead, constructivist pragmatism promotes subjective epistemology and instrumental methods. The implication for learning science is that students are encouraged to derive scientific concepts based on a combination of personal experience and personal meaningfulness. Contrary to pragmatist constructivism, however, scientific concepts do not arise inductively from subjective experience driven by personal interests. The broader implication of this study for adult education is that the philosophically laden claims of constructivist learning theories need to be identified and assessed independently of any empirical support that these learning theories might enjoy. This in turn calls for educational experiences for graduate students of education that incorporate philosophical understanding such that future educators might be able to recognize and weigh the philosophically laden claims of adult learning theories.

Environmental assessment overview

NASA Technical Reports Server (NTRS)

Valentino, A. R.

1980-01-01

The assessment program has as its objectives: to identify the environmental issues associated with the SPS Reference System; to prepare a preliminary assessment based on existing data; to suggest mitigating strategies and provide environmental data and guidance to other components of the program as required; and to plan long-range research to reduce the uncertainty in the preliminary assessment. The key environmental issues associated with the satellite power system are discussed and include human health and safety, ecosystems, climate, and interaction with electromagnetic systems.

Extension of an Object-Oriented Optimization Tool: User's Reference Manual

NASA Technical Reports Server (NTRS)

Pak, Chan-Gi; Truong, Samson S.

2015-01-01

The National Aeronautics and Space Administration Armstrong Flight Research Center has developed a cost-effective and flexible object-oriented optimization (O (sup 3)) tool that leverages existing tools and practices and allows easy integration and adoption of new state-of-the-art software. This object-oriented framework can integrate the analysis codes for multiple disciplines, as opposed to relying on one code to perform analysis for all disciplines. Optimization can thus take place within each discipline module, or in a loop between the O (sup 3) tool and the discipline modules, or both. Six different sample mathematical problems are presented to demonstrate the performance of the O (sup 3) tool. Instructions for preparing input data for the O (sup 3) tool are detailed in this user's manual.

Method for producing three-dimensional real image using radiographic perspective views of an object

DOEpatents

Ellingson, William A.; Read, Alvin A.

1976-02-24

A sequence of separate radiographs are made by indexing a radiation source along a known path relative to the object under study. Thus, each radiograph contains information from a different perspective. A holographically-recorded image is then made from each radiographic perspective by exact re-tracing of the rays through each radiographic perspective such that the re-tracing duplicates the geometry under which it was originally prepared. The holographically-stored images are simultaneously illuminated with the conjugate of the reference beam used in the original recordings. The result is the generation of a three-dimensional real image of the object such that a light-sensitive device can be moved to view the real image along any desired surface with the optical information in all other surfaces greatly suppressed.

Standardized Percentile Curves of Body Mass Index of Northeast Iranian Children Aged 25 to 60 Months

PubMed Central

Emdadi, Maryam; Safarian, Mohammad; Doosti, Hassan

2011-01-01

Objective Growth charts are widely used to assess children's growth status and can provide a trajectory of growth during early important months of life. Racial differences necessitate using local growth charts. This study aimed to provide standardized growth curves of body mass index (BMI) for children living in northeast Iran. Methods A total of 23730 apparently healthy boys and girls aged 25 to 60 months recruited for 20 days from those attending community clinics for routine health checks. Anthropometric measurements were done by trained health staff using WHO methodology. The LMSP method with maximum penalized likelihood, the Generalized Additive Models, the Box-Cox power exponential distribution distribution, Akaike Information Criteria and Generalized Akaike Criteria with penalty equal to 3 [GAIC(3)], and Worm plot and Q-tests as goodness of fit tests were used to construct the centile reference charts. Findings The BMI centile curves for boys and girls aged 25 to 60 months were drawn utilizing a population of children living in northeast Iran. Conclusion The results of the current study demonstrate the possibility of preparation of local growth charts and their importance in evaluating children's growth. Also their differences, relative to those prepared by global references, reflect the necessity of preparing local charts in future studies using longitudinal data. PMID:23056770

Electronic data collection for the analysis of surgical maneuvers on patients submitted to rhinoplasty

PubMed Central

Berger, Cezar; Freitas, Renato; Malafaia, Osvaldo; Pinto, José Simão de Paula; Mocellin, Marcos; Macedo, Evaldo; Fagundes, Marina Serrato Coelho

2012-01-01

Summary Introduction: In the health field, computerization has become increasingly necessary in professional practice, since it facilitates data recovery and assists in the development of research with greater scientific rigor. Objective: the present work aimed to develop, apply, and validate specific electronic protocols for patients referred for rhinoplasty. Methods: The prospective research had 3 stages: (1) preparation of theoretical data bases; (2) creation of a master protocol using Integrated System of Electronic Protocol (SINPE©); and (3) elaboration, application, and validation of a specific protocol for the nose and sinuses regarding rhinoplasty. Results: After the preparation of the master protocol, which dealt with the entire field of otorhinolaryngology, we idealized a specific protocol containing all matters related to the patient. In particular, the aesthetic and functional nasal complaints referred for surgical treatment (i.e., rhinoplasty) were organized into 6 main hierarchical categories: anamnesis, physical examination, complementary exams, diagnosis, treatment, and outcome. This protocol utilized these categories and their sub-items: finality; access; surgical maneuvers on the nasal dorsum, tip, and base; clinical evolution after 3, 6, and 12 months; revisional surgery; and quantitative and qualitative evaluations. Conclusion: The developed electronic-specific protocol is feasible and important for information registration from patients referred to rhinoplasty. PMID:25991979

21 CFR 660.25 - Potency tests without reference preparations.

Code of Federal Regulations, 2012 CFR

2012-04-01

... manufacturer's package insert using red blood cells showing heterozygous or diminished expression of the... SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Blood Grouping Reagent § 660.25 Potency tests without reference preparations. Products for which Reference Blood...

21 CFR 660.25 - Potency tests without reference preparations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... manufacturer's package insert using red blood cells showing heterozygous or diminished expression of the... SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Blood Grouping Reagent § 660.25 Potency tests without reference preparations. Products for which Reference Blood...

21 CFR 660.25 - Potency tests without reference preparations.

Code of Federal Regulations, 2014 CFR

2014-04-01

... manufacturer's package insert using red blood cells showing heterozygous or diminished expression of the... SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Blood Grouping Reagent § 660.25 Potency tests without reference preparations. Products for which Reference Blood...

21 CFR 660.25 - Potency tests without reference preparations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... manufacturer's package insert using red blood cells showing heterozygous or diminished expression of the... SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Blood Grouping Reagent § 660.25 Potency tests without reference preparations. Products for which Reference Blood...

21 CFR 660.25 - Potency tests without reference preparations.

Code of Federal Regulations, 2013 CFR

2013-04-01

... manufacturer's package insert using red blood cells showing heterozygous or diminished expression of the... SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Blood Grouping Reagent § 660.25 Potency tests without reference preparations. Products for which Reference Blood...

[Management by objectives: an experience by transfusion and immunology service in Rabat].

PubMed

Essakalli, M; Atouf, O; Ouadghiri, S; Bouayad, A; Drissi, A; Sbain, K; Sakri, L; Benseffaj, N; Brick, C

2013-09-01

The management by objectives method has become highly used in health management. In this context, the blood transfusion and haemovigilance service has been chosen for a pilot study by the Head Department of the Ibn Sina Hospital in Rabat. This study was conducted from 2009 to 2011, in four steps. The first one consisted in preparing human resources (information and training), identifying the strengths and weaknesses of the service and the identification and classification of the service's users. The second step was the elaboration of the terms of the contract, which helped to determine two main strategic objectives: to strengthen the activities of the service and move towards the "status of reference." Each strategic objective had been declined in operational objectives, then in actions and the means required for the implementation of each action. The third step was the implementation of each action (service, head department) so as to comply with the terms of the contract as well as to meet the deadlines. Based on assessment committees, the last step consisted in the evaluation process. This evaluation was performed using monitoring indicators and showed that management by objectives enabled the Service to reach the "clinical governance level", to optimize its human and financial resources and to reach the level of "national laboratory of reference in histocompatibility". The scope of this paper is to describe the four steps of this pilot study and to explain the usefulness of the management by objectives method in health management. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

[Troubleshooting of bioinequivalence of compound valsartan tablets].

PubMed

Shao, Da; Zhang, Yi-Fan; Zhan, Yan; Chen, Xiao-Yan; Zhong, Da-Fang

2014-04-01

The study aims to evaluate the bioequivalence of valsartan hydrochlorothiazide tablets, and to investigate the potential cause of bioinequivalence. This was a single-center study with an open, randomized double-way crossover design. Test and reference preparations containing 160 mg of valsartan and 25 mg of hydrochlorothiazide were given to 36 healthy male volunteers. Plasma concentrations of valsartan and hydrochlorothiazide were determined simultaneously by LC-MS/MS. The pharmacokinetic parameters and relative bioavailability were calculated, while the bioequivalence between test and reference preparations were evaluated. The dissolution profiles of test and reference preparations in four different mediums were determined via dissolution test and HPLC. The similarity was investigated according to the similarity factors (f2). The F(o-t) and F(0-infinity) were (139.4 +/- 65.2)% and (137.5 +/- 61.2)% for valsartan of test preparations. It led to get the conclusion that test and reference preparations were not bioequivalent for valsartan. A significant difference was observed between test and reference tablets in the valsartan dissolution test of pH 1.2 hydrochloric acid solution. The key factor of the bioinequivalence might be that dissolution of valsartan in acid medium has marked difference between two preparations.

[Preparation of flavonoid reference standards from Scutellariae Radix under the guidance of high performance liquid chromatography-mass spectrometry analysis].

PubMed

Guo, Henan; Yang, Xuedong; Liu, Jun; Zheng, Wenfeng

2012-07-01

Flavonoid reference standards were targeted-prepared from Scutellariae Radix under the guidance of high performance liquid chromatography-mass spectrometry (HPLC-MS) analysis. With HPLC-MS analysis of Scutellariae Radix, 19 flavonoid components were identified by analyzing and comparing their retention times, ultraviolet spectra, and mass spectrometry data with literature. The separation and purification protocols of all targeted flavonoid reference standards were optimally designed according to the results of HPLC-MS analysis and related literature. The ethanol extract of Scutellariae Radix was suspended in water and extracted with petroleum ether, ethyl acetate, and n-butanol successively. The ethyl acetate extract and n-butanol extract were separately subjected to primary separation by low pressure reverse phase preparative chromatography. Then the fractions containing targeted compounds were further purified by low pressure reverse and normal phases preparative chromatography. Finally, baicalin and wogonoside reference standards were obtained from n-butanol extract; baicaelin, wogonin, and oroxylin A reference standards were obtained from ethyl acetate extract. The structures of the 5 reference standards were identified by mass spectrometry (MS) and 1H nuclear magnetic resonance (1H NMR) spectroscopy. The HPLC analytical results showed that the purities of the 5 reference standards were all above 98%. It is demonstrated that the rapid targeted-preparation method under the guidance of the HPLC-MS analysis is applicable for the isolation and preparation of chemical components in traditional Chinese medicines.

21 CFR 660.52 - Reference preparations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Reference preparations. 660.52 Section 660.52 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Anti-Human Globulin § 660.52 Reference...

42 CFR 7.2 - Establishment of a user charge.

Code of Federal Regulations, 2010 CFR

2010-10-01

... DISTRIBUTION OF REFERENCE BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.2 Establishment of a user charge... producing and distributing reference biological standards and biological preparations. ...

Can you see what I am talking about? Human speech triggers referential expectation in four-month-old infants

PubMed Central

Marno, Hanna; Farroni, Teresa; Vidal Dos Santos, Yamil; Ekramnia, Milad; Nespor, Marina; Mehler, Jacques

2015-01-01

Infants’ sensitivity to selectively attend to human speech and to process it in a unique way has been widely reported in the past. However, in order to successfully acquire language, one should also understand that speech is a referential, and that words can stand for other entities in the world. While there has been some evidence showing that young infants can make inferences about the communicative intentions of a speaker, whether they would also appreciate the direct relationship between a specific word and its referent, is still unknown. In the present study we tested four-month-old infants to see whether they would expect to find a referent when they hear human speech. Our results showed that compared to other auditory stimuli or to silence, when infants were listening to speech they were more prepared to find some visual referents of the words, as signalled by their faster orienting towards the visual objects. Hence, our study is the first to report evidence that infants at a very young age already understand the referential relationship between auditory words and physical objects, thus show a precursor in appreciating the symbolic nature of language, even if they do not understand yet the meanings of words. PMID:26323990

Preparation and in vitro-in vivo evaluation of none gastric resident dipyridamole (DIP) sustained-release pellets with enhanced bioavailability.

PubMed

Xu, Lishuang; Luo, Yanfei; Feng, Jia; Xu, Ming; Tao, Xiaoguang; He, Haibing; Tang, Xing

2012-01-17

The objective of this study was to develop none gastric resident sustained-release pellets loaded with dipyridamole with a high bioavailability. Two different kinds of core pellets, one containing citric acid as a pH-modifier (CAP) and, the other without pH-modifier (NCAP) were prepared by extrusion-spheronization and then coated with mixtures of enteric soluble and insoluble polymers (referred to as CAP(1) and NCAP(1)) or insoluble polymer alone (referred to as CAP(2) and NCAP(2)). The relative bioavailability of the sustained-release pellets was studied in fasted beagle dogs after oral administration using a commercially available immediate release tablet (IRT) as a reference. The in vitro release, in vivo absorption and in vitro-in vivo correlation were also evaluated. Results revealed that the plasma drug concentrations after administration of CAP(2), NCAP(1) and NCAP(2) were undetectable, indicating that the drug release was almost zero from the preparations throughout the gastro-intestinal tract. The C(max), T(max) and AUC((0→24)) of CAP(1) were 0.78 ± 0.23 (μg/ml), 3.80 ± 0.30 (h), and 6.74 ± 0.47 (μg/mlh), respectively. While the corresponding values were 2.23 ± 0.32 (μg/ml), 3.00 ± 0.44 (h) and 9.42 ± 0.69 (μg/mlh) for IRT. The relative bioavailability of CAP(1) was 71.55% compared with IRT. By combined incorporation of a pH-modifier into the core of pellets to modify the inner micro-environment and employing mixtures of enteric soluble and insoluble polymers as a retarding layer, drugs with high solubility in stomach and limited solubility in small intestine, such as DIP, could be successfully formulated as sustained release preparations with no pH-dependence in drug release and enhanced bioavailability. Copyright © 2011 Elsevier B.V. All rights reserved.

21 CFR 660.22 - Potency requirements with reference preparations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Potency requirements with reference preparations. 660.22 Section 660.22 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN.... Products for which reference Blood Grouping Reagents are available shall have a potency titer value at...

21 CFR 660.22 - Potency requirements with reference preparations.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Potency requirements with reference preparations. 660.22 Section 660.22 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN.... Products for which reference Blood Grouping Reagents are available shall have a potency titer value at...

Astrophysics of Reference Frame Tie Objects

NASA Technical Reports Server (NTRS)

Johnston, Kenneth J.; Boboltz, David; Fey, Alan Lee; Gaume, Ralph A.; Zacharias, Norbert

2004-01-01

The Astrophysics of Reference Frame Tie Objects Key Science program will investigate the underlying physics of SIM grid objects. Extragalactic objects in the SIM grid will be used to tie the SIM reference frame to the quasi-inertial reference frame defined by extragalactic objects and to remove any residual frame rotation with respect to the extragalactic frame. The current realization of the extragalactic frame is the International Celestial Reference Frame (ICRF). The ICRF is defined by the radio positions of 212 extragalactic objects and is the IAU sanctioned fundamental astronomical reference frame. This key project will advance our knowledge of the physics of the objects which will make up the SIM grid, such as quasars and chromospherically active stars, and relates directly to the stability of the SIM reference frame. The following questions concerning the physics of reference frame tie objects will be investigated.

Nuclear Criticality Safety Data Book

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hollenbach, D. F.

The objective of this document is to support the revision of criticality safety process studies (CSPSs) for the Uranium Processing Facility (UPF) at the Y-12 National Security Complex (Y-12). This design analysis and calculation (DAC) document contains development and justification for generic inputs typically used in Nuclear Criticality Safety (NCS) DACs to model both normal and abnormal conditions of processes at UPF to support CSPSs. This will provide consistency between NCS DACs and efficiency in preparation and review of DACs, as frequently used data are provided in one reference source.

[Classifications in forensic medicine and their logical basis].

PubMed

Kovalev, A V; Shmarov, L A; Ten'kov, A A

2014-01-01

The objective of the present study was to characterize the main requirements for the correct construction of classifications used in forensic medicine, with special reference to the errors that occur in the relevant text-books, guidelines, and manuals and the ways to avoid them. This publication continues the series of thematic articles of the authors devoted to the logical errors in the expert conclusions. The preparation of further publications is underway to report the results of the in-depth analysis of the logical errors encountered in expert conclusions, text-books, guidelines, and manuals.

Neutron resonance spectroscopy for the characterization of materials and objects

NASA Astrophysics Data System (ADS)

Schillebeeckx, P.; Borella, A.; Emiliani, F.; Gorini, G.; Kockelmann, W.; Kopecky, S.; Lampoudis, C.; Moxon, M.; Perelli Cippo, E.; Postma, H.; Rhodes, N. J.; Schooneveld, E. M.; Van Beveren, C.

2012-03-01

The resonance structure in neutron induced reaction cross sections can be used to determine the elemental compositions of materials or objects. The occurrence of resonances is the basis of neutron resonance capture analysis (NRCA) and neutron resonance transmission analysis (NRTA). NRCA and NRTA are fully non-destructive methods to determine the bulk elemental composition without the need of any sample preparation and resulting in a negligible residual activity. They have been applied to determine the elemental composition of archaeological objects and to characterize reference materials used for cross section measurements. For imaging applications a position sensitive neutron detector has been developed within the ANCIENT CHARM project. The detector is based on a 10 × 10 array of 6Li-glass scintillators mounted on a pitch of 2.5 mm, resulting in a 25 × 25 mm2 active area. The detector has been tested at the time-of-flight facility GELINA and used at the ISIS spallation source to study cultural heritage objects.

Performance of Commercial Enzyme-Linked Immunosorbent Assays for Detection of Antibodies to Bordetella pertussis▿

PubMed Central

Riffelmann, M.; Thiel, K.; Schmetz, J.; Wirsing von Koenig, C. H.

2010-01-01

Measuring antibodies to Bordetella pertussis antigens is mostly done by enzyme-linked immunosorbent assays (ELISAs). We compared the performance of ELISA kits that were commercially available in Germany. Eleven measured IgG antibodies, and nine measured IgA antibodies. An in-house ELISA with purified antigens served as a reference method. Samples included two WHO reference preparations, the former Food and Drug Administration (FDA)/Center for Biologics Evaluation and Research (CBER) reference preparations, serum samples from patients with clinically suspected pertussis, and serum samples from patients having received a combined tetanus, diphtheria, and pertussis (Tdap) vaccination. Kits using pertussis toxin (PT) as an antigen showed linearity compared to the WHO Reference preparation (r2 between 0.82 and 0.99), and these kits could quantify antibodies according to the reference preparation. ELISA kits using mixed antigens showed no linear correlation to the reference preparations. Patient results were compared to results of in-house ELISAs using a dual cutoff of either ≥100 IU/ml anti-PT IgG or ≥40 IU/ml anti-PT IgG together with ≥12 IU/ml anti-PT IgA. The sensitivities of kits measuring IgG antibodies ranged between 0.84 and 1.00. The specificities of kits using PT as an antigen were between 0.81 and 0.93. The specificities of kits using mixed antigens were between 0.51 and 0.59 and were thus not acceptable. The sensitivities of kits measuring IgA antibodies ranged between 0.53 and 0.73, and the specificities were between 0.67 and 0.94, indicating that IgA antibodies may be of limited diagnostic value. Our data suggest that ELISAs should use purified PT as an antigen and be standardized to the 1st International Reference preparation. PMID:20943873

Definition of spacecraft standard interfaces by the NASA Space Assembly and Servicing Working Group (SASWG)

NASA Technical Reports Server (NTRS)

Radtke, Robert; Woolley, Charles; Arnold, Lana

1993-01-01

The purpose of the NASA Space Assembly and Servicing Working Group (SASWG) is to study enabling technologies for on-orbit spacecraft maintenance and servicing. One key technology required for effective space logistics activity is the development of standard spacecraft interfaces, including the 'Basic Set' defined by NASA, the U.S. Space Command, and industry panelists to be the following: (1) navigation aids; (2) grasping, berthing, and docking; and (3) utility connections for power, data, and fluids. Draft standards have been prepared and referred to professional standards organizations, including the AIAA, EIA, and SAE space standards committee. The objective of the SASWG is to support these committees with the technical expertise required to prepare standards, guidelines, and recommended practices which will be accepted by the ANSI and international standards organizations, including the ISO, IEC, and PASC.

Direct-to-digital holography reduction of reference hologram noise and fourier space smearing

DOEpatents

Voelkl, Edgar

2006-06-27

Systems and methods are described for reduction of reference hologram noise and reduction of Fourier space smearing, especially in the context of direct-to-digital holography (off-axis interferometry). A method of reducing reference hologram noise includes: recording a plurality of reference holograms; processing the plurality of reference holograms into a corresponding plurality of reference image waves; and transforming the corresponding plurality of reference image waves into a reduced noise reference image wave. A method of reducing smearing in Fourier space includes: recording a plurality of reference holograms; processing the plurality of reference holograms into a corresponding plurality of reference complex image waves; transforming the corresponding plurality of reference image waves into a reduced noise reference complex image wave; recording a hologram of an object; processing the hologram of the object into an object complex image wave; and dividing the complex image wave of the object by the reduced noise reference complex image wave to obtain a reduced smearing object complex image wave.

Processing the presence, placement, and properties of a distractor in spatial language tasks.

PubMed

Carlson, Laura A; Hill, Patrick L

2008-03-01

A common way to describe the location of an object is to spatially relate it to a nearby object. For such descriptions, the object being described is referred to as the located object; the object to which it is spatially related is referred to as the reference object. Typically, however, there are many nearby objects (distractors), resulting in the need for selection. We report three experiments that examine the extent to which a distractor in the display is processed during the selection of a reference object. Using acceptability ratings and production measures, we show that the presence and the placement ofa distractor have a significant impact on the assessment of the spatial relation between the located and reference objects; there is also evidence that the properties of the distractor are processed, but only under limited conditions. One implication is that the dimension that is most relevant to reference object selection is its spatial relation to the located object, rather than its salience with respect to other objects in the display.

Direct and simultaneous detection of organic and inorganic ingredients in herbal powder preparations by Fourier transform infrared microspectroscopic imaging

NASA Astrophysics Data System (ADS)

Chen, Jian-bo; Sun, Su-qin; Tang, Xu-dong; Zhang, Jing-zhao; Zhou, Qun

2016-08-01

Herbal powder preparation is a kind of widely-used herbal product in the form of powder mixture of herbal ingredients. Identification of herbal ingredients is the first and foremost step in assuring the quality, safety and efficacy of herbal powder preparations. In this research, Fourier transform infrared (FT-IR) microspectroscopic identification method is proposed for the direct and simultaneous recognition of multiple organic and inorganic ingredients in herbal powder preparations. First, the reference spectrum of characteristic particles of each herbal ingredient is assigned according to FT-IR results and other available information. Next, a statistical correlation threshold is determined as the lower limit of correlation coefficients between the reference spectrum and a larger number of calibration characteristic particles. After validation, the reference spectrum and correlation threshold can be used to identify herbal ingredient in mixture preparations. A herbal ingredient is supposed to be present if correlation coefficients between the reference spectrum and some sample particles are above the threshold. Using this method, all kinds of herbal materials in powder preparation Kouqiang Kuiyang San are identified successfully. This research shows the potential of FT-IR microspectroscopic identification method for the accurate and quick identification of ingredients in herbal powder preparations.

Research and technology goals and objectives for Integrated Vehicle Health Management (IVHM)

NASA Technical Reports Server (NTRS)

1992-01-01

Integrated Vehicle Health Management (IVHM) is defined herein as the capability to efficiently perform checkout, testing, and monitoring of space transportation vehicles, subsystems, and components before, during, and after operational This includes the ability to perform timely status determination, diagnostics, and prognostics. IVHM must support fault-tolerant response including system/subsystem reconfiguration to prevent catastrophic failures; and IVHM must support the planning and scheduling of post-operational maintenance. The purpose of this document is to establish the rationale for IVHM and IVHM research and technology planning, and to develop technical goals and objectives. This document is prepared to provide a broad overview of IVHM for technology and advanced development activities and, more specifically, to provide a planning reference from an avionics viewpoint under the OAST Transportation Technology Program Strategic Plan.

Availability Control for Means of Transport in Decisive Semi-Markov Models of Exploitation Process

NASA Astrophysics Data System (ADS)

Migawa, Klaudiusz

2012-12-01

The issues presented in this research paper refer to problems connected with the control process for exploitation implemented in the complex systems of exploitation for technical objects. The article presents the description of the method concerning the control availability for technical objects (means of transport) on the basis of the mathematical model of the exploitation process with the implementation of the decisive processes by semi-Markov. The presented method means focused on the preparing the decisive for the exploitation process for technical objects (semi-Markov model) and after that specifying the best control strategy (optimal strategy) from among possible decisive variants in accordance with the approved criterion (criteria) of the activity evaluation of the system of exploitation for technical objects. In the presented method specifying the optimal strategy for control availability in the technical objects means a choice of a sequence of control decisions made in individual states of modelled exploitation process for which the function being a criterion of evaluation reaches the extreme value. In order to choose the optimal control strategy the implementation of the genetic algorithm was chosen. The opinions were presented on the example of the exploitation process of the means of transport implemented in the real system of the bus municipal transport. The model of the exploitation process for the means of transports was prepared on the basis of the results implemented in the real transport system. The mathematical model of the exploitation process was built taking into consideration the fact that the model of the process constitutes the homogenous semi-Markov process.

Routine development of objectively derived search strategies.

PubMed

Hausner, Elke; Waffenschmidt, Siw; Kaiser, Thomas; Simon, Michael

2012-02-29

Over the past few years, information retrieval has become more and more professionalized, and information specialists are considered full members of a research team conducting systematic reviews. Research groups preparing systematic reviews and clinical practice guidelines have been the driving force in the development of search strategies, but open questions remain regarding the transparency of the development process and the available resources. An empirically guided approach to the development of a search strategy provides a way to increase transparency and efficiency. Our aim in this paper is to describe the empirically guided development process for search strategies as applied by the German Institute for Quality and Efficiency in Health Care (Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen, or "IQWiG"). This strategy consists of the following steps: generation of a test set, as well as the development, validation and standardized documentation of the search strategy. We illustrate our approach by means of an example, that is, a search for literature on brachytherapy in patients with prostate cancer. For this purpose, a test set was generated, including a total of 38 references from 3 systematic reviews. The development set for the generation of the strategy included 25 references. After application of textual analytic procedures, a strategy was developed that included all references in the development set. To test the search strategy on an independent set of references, the remaining 13 references in the test set (the validation set) were used. The validation set was also completely identified. Our conclusion is that an objectively derived approach similar to that used in search filter development is a feasible way to develop and validate reliable search strategies. Besides creating high-quality strategies, the widespread application of this approach will result in a substantial increase in the transparency of the development process of search strategies.

International reference preparations of typhoid vaccine

PubMed Central

Melikova, E. N.; Lesnjak, S. V.

1967-01-01

International collaborative laboratory studies on the International Reference Preparations of Typhoid Vaccine have so far failed to provide data on which international units for these vaccines can be based. Further assays carried out using the active mouse protection test, with immunization by the subcutaneous, intraperitoneal or intravenous route, confirmed the findings by some workers that the International Reference Preparation of Typhoid Vaccine (Acetone-Inactivated) (vaccine K) was more effective than the International Reference Preparation of Typhoid Vaccine (Heat-Phenol-Inactivated) (vaccine L), and indicated that intraperitoneal immunization was the most promising method. Vaccine K, together with the material extracted by the acetone in the preparation of the vaccine, had a significantly lower effectiveness (at the 5% probability level) only when intraperitoneal immunization was used. The reasons for the differences found between the various vaccines and routes of immunization are discussed at length. It is suggested that challenge with a strain of Salmonella moscow instead of the strain of Salm. typhi used until now gives a true infection and forms the basis of a reliable method for the potency assay of typhoid vaccines. PMID:5301738

Passive serialization in a multitasking environment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hennessey, J.P.; Osisek, D.L.; Seigh, J.W. II

1989-02-28

In a multiprocessing system having a control program in which data objects are shared among processes, this patent describes a method for serializing references to a data object by the processes so as to prevent invalid references to the data object by any process when an operation requiring exclusive access is performed by another process, comprising the steps of: permitting the processes to reference data objects on a shared access basis without obtaining a shared lock; monitoring a point of execution of the control program which is common to all processes in the system, which occurs regularly in the process'more » execution and across which no references to any data object can be maintained by any process, except references using locks; establishing a system reference point which occurs after each process in the system has passed the point of execution at least once since the last such system reference point; requesting an operation requiring exclusive access on a selected data object; preventing subsequent references by other processes to the selected data object; waiting until two of the system references points have occurred; and then performing the requested operation.« less

Preparation of Reference Material 8504, Transformer Oil

PubMed Central

Poster, Dianne L.; Schantz, Michele M.; Wise, Stephen A.

2005-01-01

A new reference material (RM), RM 8504, has been prepared for use as a diluent oil with Aroclors in transformer oil Standard Reference Materials (SRMs) 3075 to 3080 and SRM 3090 when developing and validating methods for the determination of polychlorinated biphenyls (PCBs) as Aroclors in transformer oil or similar matrices. SRMs 3075-3080 and SRM 3090 consist of individual Aroclors in the same transformer oil that was used to prepare RM 8504. A unit of RM 8504 consists of one bottle containing approximately 100 mL of transformer oil. No additional constituents have been added to the oil. PMID:27308183

The establishment of a WHO Reference Reagent for anti-malaria (Plasmodium falciparum) human serum.

PubMed

Bryan, Donna; Silva, Nilupa; Rigsby, Peter; Dougall, Thomas; Corran, Patrick; Bowyer, Paul W; Ho, Mei Mei

2017-08-05

At a World Health Organization (WHO) sponsored meeting it was concluded that there is an urgent need for a reference preparation that contains antibodies against malaria antigens in order to support serology studies and vaccine development. It was proposed that this reference would take the form of a lyophilized serum or plasma pool from a malaria-endemic area. In response, an immunoassay standard, comprising defibrinated human plasma has been prepared and evaluated in a collaborative study. A pool of human plasma from a malaria endemic region was collected from 140 single plasma donations selected for reactivity to Plasmodium falciparum apical membrane antigen-1 (AMA-1) and merozoite surface proteins (MSP-1 19 , MSP-1 42 , MSP-2 and MSP-3). This pool was defibrinated, filled and freeze dried into a single batch of ampoules to yield a stable source of naturally occurring antibodies to P. falciparum. The preparation was evaluated by an enzyme-linked immunosorbent assay (ELISA) in a collaborative study with sixteen participants from twelve different countries. This anti-malaria human serum preparation (NIBSC Code: 10/198) was adopted by the WHO Expert Committee on Biological Standardization (ECBS) in October 2014, as the first WHO reference reagent for anti-malaria (Plasmodium falciparum) human serum with an assigned arbitrary unitage of 100 units (U) per ampoule. Analysis of the reference reagent in a collaborative study has demonstrated the benefit of this preparation for the reduction in inter- and intra-laboratory variability in ELISA. Whilst locally sourced pools are regularly use for harmonization both within and between a few laboratories, the presence of a WHO-endorsed reference reagent should enable optimal harmonization of malaria serological assays either by direct use of the reference reagent or calibration of local standards against this WHO reference. The intended uses of this reference reagent, a multivalent preparation, are (1) to allow cross-comparisons of results of vaccine trials performed in different centres/with different products; (2) to facilitate standardization and harmonization of immunological assays used in epidemiology research; and (3) to allow optimization and validation of immunological assays used in malaria vaccine development.

A strange horn between Paolo Mantegazza and Charles Darwin.

PubMed

Garbarino, Carla; Mazzarello, Paolo

2013-09-01

During the preparation of an exhibition in Pavia dedicated to the centennial anniversary of the death of the Italian Pathologist Paolo Mantegazza, a strange cheratinic horn was found at the Museum for the History of the University of Pavia labelled as 'spur of a cock transplanted into an ear of a cow.' After some historical investigation, we found this strange object was at the centre of a scientific correspondence between Mantegazza and Charles Darwin, who made reference to it in his book The Variation of Animals and Plants under Domestication. Copyright © 2013 Elsevier Ltd. All rights reserved.

Recommendations for reference method for haemoglobinometry in human blood (ICSH standard 1986) and specifications for international haemiglobincyanide reference preparation (3rd edition). International Committee for Standardization in Haematology; Expert Panel on Haemoglobinometry.

PubMed

1987-01-01

Scientific symposia on haemoglobinometry were held at the 9th Congress of the European Society of Haematology, Lisbon, 1963 (ESH 1964) and the 10th Congress of the International Society of Haematology (ISH), Stockholm, 1964 (ISH 1965). The International Committee for Standardization in Haematology (ICSH) made recommendations endorsed by the General Assembly of ICSH in Sydney on 23 August 1966 (ICSH 1967), for a reference method for haemoglobinometry and for the manufacture and distribution of an international reference preparation. Further symposia were held at the 12th Congress of the ISH, New York, 1968 (Astaldi, Sirtori & Vanzetti 1979) and at the 13th Congress of ISH, Munich, 1970 (Izak & Lewis 1972). The recommendations were reissued in 1978 (ISH 1978). On the basis of continuing experimental studies, the reference method and the specifications for the international reference preparation have been modified. The revised recommendations are described in this document.

Joint Test Report for Validation of Alternative Low-Emission Surface Preparation/Depainting Technologies for Structural Steel

NASA Technical Reports Server (NTRS)

Lewis, Pattie

2007-01-01

Headquarters National Aeronautics and Space Administration (NASA) chartered the NASA Acquisition Pollution Prevention (AP2) Office to coordinate agency activities affecting pollution prevention issues identified during system and component acquisition and sustainment processes. The primary objectives of the AP2 Office are to: (1) Reduce or eliminate the use of hazardous materials or hazardous processes at manufacturing, remanufacturing, and sustainment locations. (2) Avoid duplication of effort in actions required to reduce or eliminate hazardous materials through joint center cooperation and technology sharing. The objective of this project was to qualify candidate alternative Low-Emission Surface Preparation/Depainting Technologies for Structural Steel applications at NASA facilities. This project compares the surface preparation/depainting performance of the proposed alternatives to existing surface preparation/depainting systems or standards. This Joint Test Report (JTR) contains the results of testing as per the outlines of the Joint Test Protocol (JTP), Joint Test Protocol for Validation of Alternative Low-Emission Surface Preparation/Depainting Technologies for Structural Steel, and the Field Test Plan (FTP), Field Evaluations Test Plan for Validation of Alternative Low-Emission Surface Preparation/Depainting Technologies for Structural Steel, for critical requirements and tests necessary to qualify alternatives for coating removal systems. These tests were derived from engineering, performance, and operational impact (supportability) requirements defined by a consensus of government and industry participants. This JTR documents the results of the testing as well as any test modifications made during the execution of the project. This JTR is made available as a reference for future pollution prevention endeavors by other NASA Centers, the Department of Defense and commercial users to minimize duplication of effort. The current coating removal processes identified herein are for polyurethane, epoxy and other paint systems applied by conventional wet-spray processes. A table summarizes the target hazardous materials, processes and materials, applications, affected programs, and candidate substrates.

Synergetic analgesic effect of the combination of arnica and hydroxyethyl salicylate in ethanolic solution following cutaneous application by transcutaneous electrostimulation.

PubMed

Kucera, Miroslav; Horácek, Ondrej; Kálal, Jan; Kolár, Pavel; Korbelar, Peter; Polesná, Zora

2003-01-01

A combination of the active agents arnica and hydroxyethyl salicylate (HES) in ethanolic solution (Sportino Acute Spray) is cutaneously applied for the treatment of sports injuries and diseases of the locomotor apparatus. The aim was to examine the efficacy and synergism of the single substances and the combination with regard to the analgesic effect after cutaneous application as well as to validate the method of transcutaneous electronic stimulation as a method of measuring the analgesic effect. In the present article, the method of transcutaneous electrostimulation was used in a randomized, controlled, single-blind trial on healthy volunteers to provide objective evidence that the combination of active agents displays a significantly greater analgesic effect than the individual active agents. Thus there is synergy between the active agents arnica and hydroxyethyl salicylate in the combination preparation. In addition, the effect of the vehicle ethanol and the reference substance water could be determined within the framework of these comparative experiments and the difference between the combination preparation and the individual substances arnica and HES could be shown. The method of transcutaneous electrostimulation used for the objective measurement of the analgesic effect was validated.

Preparing Instructional Objectives: Agony or Ecstasy?

ERIC Educational Resources Information Center

Roberts, Wesley K.

This paper 1) discusses the problems encountered in preparing objectives for instructional programs; 2) describes an informal research project in which seven instructional designers working on the same project attempted to determine agreement on an objective; and 3) suggests how to prepare objectives so that difficulties can be minimized. One…

Method and apparatus for detecting internal structures of bulk objects using acoustic imaging

DOEpatents

Deason, Vance A.; Telschow, Kenneth L.

2002-01-01

Apparatus for producing an acoustic image of an object according to the present invention may comprise an excitation source for vibrating the object to produce at least one acoustic wave therein. The acoustic wave results in the formation of at least one surface displacement on the surface of the object. A light source produces an optical object wavefront and an optical reference wavefront and directs the optical object wavefront toward the surface of the object to produce a modulated optical object wavefront. A modulator operatively associated with the optical reference wavefront modulates the optical reference wavefront in synchronization with the acoustic wave to produce a modulated optical reference wavefront. A sensing medium positioned to receive the modulated optical object wavefront and the modulated optical reference wavefront combines the modulated optical object and reference wavefronts to produce an image related to the surface displacement on the surface of the object. A detector detects the image related to the surface displacement produced by the sensing medium. A processing system operatively associated with the detector constructs an acoustic image of interior features of the object based on the phase and amplitude of the surface displacement on the surface of the object.

A Thermal Stability Test for Primary Explosive Stab Sensitizers: Study of the Thermal and Hydrolytic Stability of 2-Picryl-5-Nitrotetrazole,

DTIC Science & Technology

1984-02-01

have been described previously (2]. The actual batch used was designated Batch D and was identical to that referred to as Batch C in Reference [2...Tetrazene was type RD1357 prepared at Materials Research Laboratories. The batch used was designated Batch 10/83(A). Lead Azide was type RD1343 and was...Preparation of Experimental Detonators Eperimental detonators were prepared in mild steel tubes, 6 mm o.d., 3.2 mm i.d., length 6 mm, prepared from

78 FR 47319 - Fee Schedule for Reference Biological Standards and Biological Preparations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-05

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Fee Schedule for Reference Biological Standards and Biological Preparations AGENCY: Centers for Disease Control and Prevention (CDC), Department of Health and Human Services (HHS). ACTION: General notice. SUMMARY: The Centers...

Palatability of a Novel Oral Formulation of Prednisone in Healthy Young Adults

PubMed Central

Bai, Shasha; Dormer, Nathan; Shoults, Catherine; Meyer, Amanda; Pierce, Carol D'Ann; Neville, Kathleen A.; Kearns, Gregory L.

2017-01-01

Objectives Prednisone is a widely used anti-inflammatory for a variety of conditions. While oral liquid formulations of prednisone enable weight-based dosing, children frequently find them to be objectionable due to bitter taste. This limitation of prednisone can adversely impact patient acceptance and may result in non-compliance. Efforts to mask flavors often result in poorly controlled, heterogeneous particle distributions and can provide ineffective taste masking. The present work utilized a novel drug delivery technology developed by Orbis Biosciences, Inc., to create an oral taste-masked formulation of prednisone. Methods The study examined the palatability of Orbis’ microsphere prednisone formulation in healthy young adults (n=24). Four test articles were used in the study including a reference formulation (Roxane Laboratories), a control, and the test formulation (Orbis) prepared in two different ways. Study participants were randomized in a crossover design. Key Findings Results indicated that the test prednisone formulation was indistinguishable from the control, and both were preferable to the reference formulation in every category of palatability assessed using a validated 9-point Hedonic Scale. The data also suggested that preparing the microsphere suspension immediately prior to administration results in the most ideal palatability properties. Conclusions In conclusion, the novel microsphere formulation technology was effective in taste-masking prednisone. PMID:28271493

Glycerophosphate does not interact with components of parenteral nutrition.

PubMed

Topp, Heinrich; Hochfeld, Olena; Bark, Staffan; Grossmann, Matthias; Joukhadar, Christian; Westphal, Martin; Straatsma, Harald; Rothenburger, Markus

2011-01-01

The primary objective of this study was to determine and compare the pharmacokinetic (PK) profiles of inorganic phosphate in the serum after continuous administration of pure glycerophosphate and glycerophosphate contained in total parenteral nutrition (TPN) emulsions. This approach was selected to identify potential PK interactions between TPN components and glycerophosphate. The serum PK profile of inorganic phosphate after continuous intravenous administration of a sodium glycerophosphate containing TPN emulsion was determined in 10 healthy, white (5 male/5 female) volunteers. A pure sodium glycerophosphate formulation served as reference. Standard criteria of bioequivalence were applied. Subjects were enrolled in the double-blinded study and were randomly allocated to receive the test and reference preparations on two occasions in a 2-sequence crossover study design. The volunteers received 1/3 of the maximum recommended body weight- (BW) adjusted intravenous daily dosage (13.3 ml/kg BW) of the test drug over a period of 8 h. The amount of total phosphate (0.101 mmol/kg) and duration of administration were identical for the test and reference drugs. Study days were separated by washout periods of at least 88 h. Serum concentrations of total inorganic phosphate were measured serially over a 36-hour period using a validated method. A statistical mixed ANOVA, based on population averages, was used for testing bioequivalence between these study preparations. The 90% confidence intervals (90% CIs) of inorganic phosphate in serum were calculated for the test/reference ratios of the area under the time-concentration curve from time 0 to 36 h (AUC₀₋₃₆), the maximum concentration (C(max)) and the concentration 5 min before the end of infusion (C(ss)) for a bioequivalence range from 0.80 to 1.25. The mean test/reference ratios fell completely within the 90% CIs with values of 1.016 (90% CI 1.005-1.028), 1.013 (90% CI 0.981-1.047) and 0.932 (90% CI 0.886-0.980) for AUC(0-36), C(max) and C(ss), respectively. In total, 3 mild adverse events in the reference group were detected after starting intravenous infusion, while no adverse events were observed in the test group after treatment. Primary PK parameters were within the defined bioequivalence range of 0.8-1.25. Thus, inorganic phosphate levels were essentially similar between the two investigational medicinal products tested in the present study. These findings confirm the concept that nutritional components of the test drug do not significantly interact with glycerophosphate. The two study preparations proved to be safe during the investigation. Copyright © 2011 S. Karger AG, Basel.

A PROCEDURE FOR ESTABLISHING TRACEABILITY OF GAS MIXTURES TO CERTAIN NATIONAL BUREAU OF STANDARDS STANDARD REFERENCE MATERIALS

EPA Science Inventory

This procedure includes the specifications and requirements that must be followed by gas manufacturers during the preparation of compressed cylinder gas Certified Reference Materials (CRM). A CRM is a certified gas standard prepared at a concentration that does not exceed + or - ...

78 FR 57293 - Distribution of Reference Biological Standards and Biological Preparations

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

... DEPARTMENT OF HEALTH AND HUMAN SERVICES 42 CFR Part 7 [Docket No. CDC-2013-0013] RIN 0920-AA52 Distribution of Reference Biological Standards and Biological Preparations AGENCY: Centers for Disease Control and Prevention (HHS/CDC), Department of Health and Human Services (HHS). ACTION: Confirmation of...

Development of mass measurement equipment using an electronic mass-comparator for gravimetric preparation of reference gas mixtures

NASA Astrophysics Data System (ADS)

Matsumoto, Nobuhiro; Watanabe, Takuro; Maruyama, Masaaki; Horimoto, Yoshiyuki; Maeda, Tsuneaki; Kato, Kenji

2004-06-01

The gravimetric method is the most popular method for preparing reference gas mixtures with high accuracy. We have designed and manufactured novel mass measurement equipment for gravimetric preparation of reference gas mixtures. This equipment consists of an electronic mass-comparator with a maximum capacity of 15 kg and readability of 1 mg and an automatic cylinder exchanger. The structure of this equipment is simpler and the cost is much lower than a conventional mechanical knife-edge type large balance used for gravimetric preparation of primary gas mixtures in Japan. This cylinder exchanger can mount two cylinders alternatively on the weighing pan of the comparator. In this study, the performance of the equipment has been evaluated. At first, the linearity and repeatability of the mass measurement were evaluated using standard mass pieces. Then, binary gas mixtures of propane and nitrogen were prepared and compared with those prepared with the conventional knife-edge type balance. The comparison resulted in good consistency at the compatibility criterion described in ISO6143:2001.

Development of a reference material of a single DNA molecule for the quality control of PCR testing.

PubMed

Mano, Junichi; Hatano, Shuko; Futo, Satoshi; Yoshii, Junji; Nakae, Hiroki; Naito, Shigehiro; Takabatake, Reona; Kitta, Kazumi

2014-09-02

We developed a reference material of a single DNA molecule with a specific nucleotide sequence. The double-strand linear DNA which has PCR target sequences at the both ends was prepared as a reference DNA molecule, and we named the PCR targets on each side as confirmation sequence and standard sequence. The highly diluted solution of the reference molecule was dispensed into 96 wells of a plastic PCR plate to make the average number of molecules in a well below one. Subsequently, the presence or absence of the reference molecule in each well was checked by real-time PCR targeting for the confirmation sequence. After an enzymatic treatment of the reaction mixture in the positive wells for the digestion of PCR products, the resultant solution was used as the reference material of a single DNA molecule with the standard sequence. PCR analyses revealed that the prepared samples included only one reference molecule with high probability. The single-molecule reference material developed in this study will be useful for the absolute evaluation of a detection limit of PCR-based testing methods, the quality control of PCR analyses, performance evaluations of PCR reagents and instruments, and the preparation of an accurate calibration curve for real-time PCR quantitation.

What’s New? Children Prefer Novelty in Referent Selection

PubMed Central

Horst, Jessica S.; Samuelson, Larissa K.; Kucker, Sarah C.; McMurray, Bob

2010-01-01

Determining the referent of a novel name is a critical task for young language learners. The majority of studies on children’s referent selection focus on manipulating the sources of information (linguistic, contextual and pragmatic) that children can use to solve the referent mapping problem. Here, we take a step back and explore how children’s endogenous biases towards novelty and their own familiarity with novel objects influence their performance in such a task. We familiarized 2-year-old children with previously novel objects. Then, on novel name referent selection trials children were asked to select the referent from three novel objects: two previously seen and one completely novel object. Children demonstrated a clear bias to select the most novel object. A second experiment controls for pragmatic responding and replicates this finding. We conclude, therefore, that children’s referent selection is biased by previous exposure and children’s endogenous bias to novelty. PMID:21092945

Comparison of a portable micro-X-ray fluorescence spectrometry with inductively coupled plasma atomic emission spectrometry for the ancient ceramics analysis

NASA Astrophysics Data System (ADS)

Papadopoulou, D. N.; Zachariadis, G. A.; Anthemidis, A. N.; Tsirliganis, N. C.; Stratis, J. A.

2004-12-01

Two multielement instrumental methods of analysis, micro X-ray fluorescence spectrometry (micro-XRF) and inductively coupled plasma atomic emission spectrometry (ICP-AES) were applied for the analysis of 7th and 5th century B.C. ancient ceramic sherds in order to evaluate the above two methods and to assess the potential to use the current compact and portable micro-XRF instrument for the in situ analysis of ancient ceramics. The distinguishing factor of interest is that micro-XRF spectrometry offers the possibility of a nondestructive analysis, an aspect of primary importance in the compositional analysis of cultural objects. Micro-XRF measurements were performed firstly directly on the ceramic sherds with no special pretreatment apart from surface cleaning (micro-XRF on sherds) and secondly on pressed pellet disks which were prepared for each ceramic sherd (micro-XRF on pellet). For the ICP-AES determination of elements, test solutions were prepared by the application of a microwave-assisted decomposition procedure in closed high-pressure PFA vessels. Also, the standard reference material SARM 69 was used for the efficiency calibration of the micro-XRF instrument and was analysed by both methods. In order to verify the calibration, the standard reference materials NCS DC 73332 and SRM620 as well as the reference materials AWI-1 and PRI-1 were analysed by micro-XRF. Elemental concentrations determined by the three analytical procedures (ICP-AES, micro-XRF on sherds and micro-XRF on pellets) were statistically treated by correlation analysis and Student's t-test (at the 95% confidence level).

Reference Materials and Subject Matter Knowledge Codes for Airman Knowledge Testing

DOT National Transportation Integrated Search

2004-06-08

The listings of reference materials and subject matter knowledge codes have been : prepared by the Federal Aviation Administration (FAA) to establish specific : references for all knowledge standards. The listings contain reference materials : to be ...

System Data Bases In European Satellites Programs: Lessons Learned and Recommendations

NASA Astrophysics Data System (ADS)

Passot, X.; Denuault, D.; Guiral, Ph.; Kerjean, L.; Lebreton, D.; Lecrvain, C.; Valera, S.

2007-08-01

This paper is intended for European space eningeers who must design or interact with all or part of a system database, hereafter referred to as 'SDB'. The document presents the objectives of a system database (SDB), describes the development of an SDB project from the specification stage until operations, and preovides recommendations so that an effective system can be obtained. As part of return on experience, the document gives an overview of exisiting systems in the European space industry. To prepare the new systems, it presents the services to be provided, the tools available and the emerging standars towards which SDBs must converge.

Titanium oxo-clusters: precursors for a Lego-like construction of nanostructured hybrid materials.

PubMed

Rozes, Laurence; Sanchez, Clément

2011-02-01

Titanium oxo-clusters, well-defined monodispersed nano-objects, are appropriate nano-building blocks for the preparation of organic-inorganic materials by a bottom up approach. This critical review proposes to present the different structures of titanium oxo-clusters referenced in the literature and the different strategies followed to build up hybrid materials with these versatile building units. In particular, this critical review cites and reports on the most important papers in the literature, concentrating on recent developments in the field of synthesis, characterization, and the use of titanium oxo-clusters for the construction of advanced hybrid materials (137 references).

Preschoolers' Preparation for Retrieval in Object Relocation Tasks.

ERIC Educational Resources Information Center

Beal, Carole R.; Fleisig, Wayne E.

The finding that young children do not prepare markers to help themselves relocate objects after a delay may have resulted from children's misunderstanding of the difficulty of unassisted retrieval. This study examined children's ability to recognize that they should prepare markers in two simplified object relocation tasks after they had been…

Formulation and evaluation of a montelukast sodium orally disintegrating tablet with a similar dissolution profile as the marketed product.

PubMed

Chen, Yong; Feng, Tingting; Li, Yong; Du, Bin; Weng, Weiyu

2017-03-01

A major challenge of orally disintegrating tablet (ODT) development is predicting its bioequivalence to its corresponding marketed product. Therefore, comparing ODT dissolution profiles to those of the corresponding marketed product is very important. The objective of this study was to develop a 5.2-mg montelukast sodium (MS) ODT with a similar dissolution profile to that of the marketed chewable tablet. Dissolution profiles were examined in different media to screen each formulation. We found that MS dissolution from ODTs in acidic medium heavily depended on manufacturing methods. All MS ODTs prepared using direct compression rapidly disintegrated in acidic medium. However, dispersed MS powders aggregated into sticky masses, resulting in slow dissolution. In contrast, MS ODTs prepared using wet granulation had much faster dissolution rates in acidic medium with no obvious aggregation. Additionally, the optimized formulation, prepared using wet granulation, displayed similar dissolution profiles to the marketed reference in all four types of media examined (f 2  >   50). The in vitro disintegration time of the optimized ODT was 9.5 ± 2.4 s, which meets FDA requirements. In conclusion, the wet granulation preparation method of MS ODTs resulted in a product with equivalent dissolution profiles as those of the marketed product.

Appropriateness of culinary preparations of potato (Solanum tuberosum L.) varieties and relation to sensory and physicochemical properties.

PubMed

Seefeldt, Helene F; Tønning, Erik; Wiking, Lars; Thybo, Anette K

2011-02-01

Appropriateness of potatoes for culinary preparations is defined as the optimal use of a given variety for a specific culinary preparation. The aim of this study was to examine the sensory attributes and physicochemical characteristics (dry matter content, starch properties, instrumental texture) of 11 potato varieties in relation to their appropriateness for boiling, oven-frying or mashing. The reproducibility of appropriateness was studied by including the effect of two growing conditions and yearly variation combined with internal references. The potato varieties, tested by 31 evaluators in two years, showed three groupings differing in appropriateness, which could be explained by a few sensory attributes: yellowness, mealiness, creaminess and butter taste. The physicochemical data showed a large variation of 23-25% in dry matter content, amylose content and starch granule size and an extreme variation in texture hardness. High reproducibility was found in the ranking of potatoes across years and culinary preparations. Hence, if a variety was judged well appropriate for boiled potatoes, it was also judged well appropriate as mashed or oven-fried potatoes. This study showed the relevance of using sensory descriptors appropriateness in an objective manner. A few sensory descriptors can be used in consumer-labelling appropriateness of potatoes. 2010 Society of Chemical Industry.

System and method for authentication

DOEpatents

Duerksen, Gary L.; Miller, Seth A.

2015-12-29

Described are methods and systems for determining authenticity. For example, the method may include providing an object of authentication, capturing characteristic data from the object of authentication, deriving authentication data from the characteristic data of the object of authentication, and comparing the authentication data with an electronic database comprising reference authentication data to provide an authenticity score for the object of authentication. The reference authentication data may correspond to one or more reference objects of authentication other than the object of authentication.

Arab oil: impact on the Arab countries and global implications. [16 papers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sherbiny, N.A.; Tessler, M.A.

1976-01-01

The objectives in preparing this volume are threefold. First, at a time when misconceptions about the impact of Arab oil are current in the West, objective and reasoned judgments about the implications of growing Arab oil wealth are sought. To judge by accounts in the news media and the popular stereotypes to which they seem to lead, many believe the world economic and political system is seriously threatened by the Arabs. Some also apparently believe that the Arab world itself is being altered beyond recognition . . . . Taken as a group, the chapters in this volume lay tomore » rest such popular misconceptions and place in their proper perspective the changes being brought about by Arab oil wealth. Second, this volume is intended to fill a gap in the small but growing body of scholarly literature on Arab oil. A number of excellent studies have appeared in recent years, but most have been written from the perspective of a single discipline and/or ideology. Further, the majority of these works focus on the international consequences of Arab oil and neglect forces operating within the Arab oil-producing countries themselves . . . . In preparing this volume, an objective was to bring together a wide variety of viewpoints in order to present a comprehensive and balanced examination of the impact of Arab oil. Third, the volume is an assemblage of 16 papers for the specialist and the nonspecialist reader. It attempts to serve as a ready reference on the topic of Arab oil.« less

[Reference values for the blood coagulation tests in Mexico: usefulness of the pooled plasma from blood donors].

PubMed

Calzada-Contreras, Adriana; Moreno-Hernández, Manuel; Castillo-Torres, Noemi Patricia; Souto-Rosillo, Guadalupe; Hernández-Juárez, Jesús; Ricardo-Moreno, María Tania; Sánchez-Fernández, Maria Guadalupe de Jesús; García-González, América; Majluf-Cruz, Abraham

2012-01-01

The blood coagulation system maintains the blood in a liquid state and bleeding and thrombosis are the manifestations of its malfunction. Blood coagulation laboratory evaluates the physiology of this system. To establish both, the reference values for several tests performed at the blood coagulation laboratory as well as the utility of the pooled plasma to perform these assays. MATERIAL AND: In this descriptive, cross-sectional, randomized study, we collected plasma from Mexican Mestizos. Each pooled plasma was prepared with the plasma from at least 20 blood donors. We performed screening and special tests and the Levey-Jennings graphs were built and interpreted after each pass. Results of the tests were analyzed and their distribution was established using the Kolmogorov-Smirnov test. To establish the reference values we used 95% confidence intervals. We collected 72 pooled plasmas. The distribution for PT, APTT, and TT tests was abnormal. Although the PT test showed a bimodal distribution it was normal for factor VII. The reference values for the hemostatic, anticoagulant, and fibrinolytic factors were different from those suggested by the manufacturers. We established the reference values for the blood coagulation tests in the adult Mexican population. We have shown that the pooled plasma must be used for the screening tests. We suggest that each clinical laboratory should establish its own reference values (at least for the screening tests). To reach this objective, we encourage the use of the pooled plasma.

Optical vibration detection spectral analysis assembly and method for detecting vibration in an object of interest

DOEpatents

Hale, Thomas C.; Telschow, Kenneth L.

1998-01-01

A vibration detection assembly is described which includes an emitter of light which has object and reference beams, the object beam reflected off of a vibrating object of interest; and a photorefractive substance having a given response time and which passes the reflected object beam and the reference beam, the reference beam and the object beam interfering within the photorefractive substance to create a space charge field which develops within the response time of the photorefractive substance.

Optical vibration detection spectral analysis assembly and method for detecting vibration in an object of interest

DOEpatents

Hale, T.C.; Telschow, K.L.

1998-10-27

A vibration detection assembly is described which includes an emitter of light which has object and reference beams, the object beam reflected off of a vibrating object of interest; and a photorefractive substance having a given response time and which passes the reflected object beam and the reference beam, the reference beam and the object beam interfering within the photorefractive substance to create a space charge field which develops within the response time of the photorefractive substance. 6 figs.

Objectively Measured Physical Activity in Home Guard Soldiers During Military Service and Civilian Life.

PubMed

Aandstad, Anders; Hageberg, Rune; Holme, Ingar M; Anderssen, Sigmund A

2016-07-01

Soldiers are encouraged to be physically active, and thereby maintain or increase their fitness level to meet job-related physical demands. However, studies on objectively measured physical activity (PA) in soldiers are scarce, particular for reserve soldiers. Hence, the aim of this study was to present PA data on Norwegian Home Guard (HG) soldiers. A total of 411 HG soldiers produced acceptable PA measurements (SenseWear Armband Pro2) during civilian life, of which 299 soldiers also produced acceptable data during HG military training. Reference data on total energy expenditure, metabolic equivalents, steps per day, and minutes of PA in three different metabolic equivalent categories are presented. The HG soldiers produced more minutes of moderate PA during HG military training compared to civilian life, but less vigorous and very vigorous PA. Furthermore, HG soldiers were more physically active during civilian week days compared to weekend days. The presented reference data can be used for comparisons against other groups of soldiers. Our data indicate that aerobic demands during HG military training were not very high. Promoting PA and exercise could still be important to ensure HG soldiers are physically prepared for more unforeseen job tasks. Reprint & Copyright © 2016 Association of Military Surgeons of the U.S.

Starting and Operating Live Virtual Reference Services: A How-To-Do-It Manual for Librarians. How-To-Do-It Manuals for Librarians, Number 118.

ERIC Educational Resources Information Center

Meola, Marc; Stormont, Sam

This guide discusses the essentials of live virtual reference, preparing for virtual reference, and implementing and incorporating virtual reference. Chapter 1, "Understanding Live Virtual Reference," lays out what virtual reference is and how it compares to other forms of reference. Chapter 2, "Offering Live Virtual Reference," presents ten…

Preparation and stability of milk somatic cell reference materials.

PubMed

Di Marzo, Larissa; Wojciechowski, Karen L; Barbano, David M

2016-09-01

Our objectives were to develop a method to produce milk somatic cell count (SCC) reference materials for calibration of electronic somatic cell count (ESCC) using gravity separation and to determine the effect of refrigerated storage (4°C) and freeze-thaw stability of the skim and whole milk SCC reference materials. Whole raw milk was high-temperature short-time pasteurized and split into 2 portions. One portion was gravity separated at 4°C for 22 h and the second portion was centrifugally separated to produce skim milk that was also gravity separated with somatic cells rising to the surface. After 22 h, stock solutions (low SCC skim milk, high SCC skim milk, high SCC whole milk) were prepared and preserved (bronopol). Two experiments were conducted, one to compare the shelf-life of skim and whole milk SCC standards at 4°C and one to determine the effect of freezing and thawing on SCC standards. Both experiments were replicated 3 times. Gravity separation was an effective approach to isolate and concentrate somatic cells from bovine milk and redistribute them in a skim or whole milk matrix to create a set of reference materials with a wider and more uniformly distributed range of SCC than current calibration sets. The liquid SCC reference materials stored using the common industry practice at 4°C were stable (i.e., fit for purpose, no large decrease in SCC) for a 2-wk period, whereas frozen and thawed reference materials may have a much longer useful life. A gradual decrease occurred in residual difference in ESCC (SCC × 1,000/mL) versus original assigned reference SCC over duration of refrigerated storage for both skim and whole milk SCC samples, indicating that milk ESCC of the preserved milks was gradually decreasing during 28 d of storage at 4°C by about 15,000 SCC/mL. No difference in the ESCC for skim milk was detected between refrigerated and frozen storage, whereas for whole milk the ESCC for frozen was lower than refrigerated samples. Future work is needed to determine the time and temperature of longer term frozen storage over which the SCC results are stable. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Acoustic imaging microscope

DOEpatents

Deason, Vance A.; Telschow, Kenneth L.

2006-10-17

An imaging system includes: an object wavefront source and an optical microscope objective all positioned to direct an object wavefront onto an area of a vibrating subject surface encompassed by a field of view of the microscope objective, and to direct a modulated object wavefront reflected from the encompassed surface area through a photorefractive material; and a reference wavefront source and at least one phase modulator all positioned to direct a reference wavefront through the phase modulator and to direct a modulated reference wavefront from the phase modulator through the photorefractive material to interfere with the modulated object wavefront. The photorefractive material has a composition and a position such that interference of the modulated object wavefront and modulated reference wavefront occurs within the photorefractive material, providing a full-field, real-time image signal of the encompassed surface area.

High accuracy Primary Reference gas Mixtures for high-impact greenhouse gases

NASA Astrophysics Data System (ADS)

Nieuwenkamp, Gerard; Zalewska, Ewelina; Pearce-Hill, Ruth; Brewer, Paul; Resner, Kate; Mace, Tatiana; Tarhan, Tanil; Zellweger, Christophe; Mohn, Joachim

2017-04-01

Climate change, due to increased man-made emissions of greenhouse gases, poses one of the greatest risks to society worldwide. High-impact greenhouse gases (CO2, CH4 and N2O) and indirect drivers for global warming (e.g. CO) are measured by the global monitoring stations for greenhouse gases, operated and organized by the World Meteorological Organization (WMO). Reference gases for the calibration of analyzers have to meet very challenging low level of measurement uncertainty to comply with the Data Quality Objectives (DQOs) set by the WMO. Within the framework of the European Metrology Research Programme (EMRP), a project to improve the metrology for high-impact greenhouse gases was granted (HIGHGAS, June 2014-May 2017). As a result of the HIGHGAS project, primary reference gas mixtures in cylinders for ambient levels of CO2, CH4, N2O and CO in air have been prepared with unprecedented low uncertainties, typically 3-10 times lower than usually previously achieved by the NMIs. To accomplish these low uncertainties in the reference standards, a number of preparation and analysis steps have been studied and improved. The purity analysis of the parent gases had to be performed with lower detection limits than previously achievable. E.g., to achieve an uncertainty of 2•10-9 mol/mol (absolute) on the amount fraction for N2O, the detection limit for the N2O analysis in the parent gases has to be in the sub nmol/mol domain. Results of an OPO-CRDS analyzer set-up in the 5µm wavelength domain, with a 200•10-12 mol/mol detection limit for N2O, will be presented. The adsorption effects of greenhouse gas components at cylinder surfaces are critical, and have been studied for different cylinder passivation techniques. Results of a two-year stability study will be presented. The fit-for-purpose of the reference materials was studied for possible variation on isotopic composition between the reference material and the sample. Measurement results for a suit of CO2 in air mixtures with varying δ13C values (from -5‰ to -40‰) analyzed with both cavity ringdown spectroscopy (CRDS) and isotope-ratio mass spectrometry (IRMS) will be presented. Round robins were organized to assess the agreement of the new reference gas mixtures developed by different project partners and to compare the new reference gases with the reference standards currently used by the atmospheric monitoring community (NOAA and AGAGE). These results will also be presented.

Border collie comprehends object names as verbal referents.

PubMed

Pilley, John W; Reid, Alliston K

2011-02-01

Four experiments investigated the ability of a border collie (Chaser) to acquire receptive language skills. Experiment 1 demonstrated that Chaser learned and retained, over a 3-year period of intensive training, the proper-noun names of 1022 objects. Experiment 2 presented random pair-wise combinations of three commands and three names, and demonstrated that she understood the separate meanings of proper-noun names and commands. Chaser understood that names refer to objects, independent of the behavior directed toward those objects. Experiment 3 demonstrated Chaser's ability to learn three common nouns--words that represent categories. Chaser demonstrated one-to-many (common noun) and many-to-one (multiple-name) name-object mappings. Experiment 4 demonstrated Chaser's ability to learn words by inferential reasoning by exclusion--inferring the name of an object based on its novelty among familiar objects that already had names. Together, these studies indicate that Chaser acquired referential understanding of nouns, an ability normally attributed to children, which included: (a) awareness that words may refer to objects, (b) awareness of verbal cues that map words upon the object referent, and (c) awareness that names may refer to unique objects or categories of objects, independent of the behaviors directed toward those objects. Copyright © 2010 Elsevier B.V. All rights reserved.

A New Bibliographical Feature for SIMBAD: Highlighting the Most Relevant Papers for One Astronomical Object

NASA Astrophysics Data System (ADS)

Oberto, A.; Lesteven, S.; Derriere, S.; Bonnin, C.; Buga, M.; Brouty, M.; Bruneau, C.; Brunet, C.; Eisele, A.; Genova, F.; Guéhenneux, S.; Neuville, M.; Ochsenbein, F.; Perret, E.; Son, E.; Vannier, P.; Vonflie, P.; Wenger, M.; Woelfel, F.

2015-04-01

The number of bibliographical references attached to an astronomical object in SIMBAD is has been growing continuously over the years. It is important for astronomers to retrieve the most relevant papers, those that give important information about the object of study. This is not easy since there can be many references attached to one object. For instance, in 2014, more than 15,000 objects had been attached to more than 50 references. The location of the object's citations inside the paper and its number of occurrences are important criteria to extract the most relevant papers. Since 2008, because of the DJIN application (a semi-automatic tool to search for object names in full text) this information has been collected. For each article associated with an astronomical object, we know where it is cited and how many times and with which name it appears. Since September 2013, the users of SIMBAD web site can choose to retrieve the most relevant references for an astronomical object depending on its location in the publication. A new formula to sort references by combining all locations, number of occurrences, total number of objects studied, citation count, and year is presented in this paper.

Metonymy and Reference-Point Errors in Novice Programming

ERIC Educational Resources Information Center

Miller, Craig S.

2014-01-01

When learning to program, students often mistakenly refer to an element that is structurally related to the element that they intend to reference. For example, they may indicate the attribute of an object when their intention is to reference the whole object. This paper examines these reference-point errors through the context of metonymy.…

Nuclear Magnetic Dipole and Electric Quadrupole Moments: Their Measurement and Tabulation as Accessible Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stone, N. J., E-mail: n.stone@physics.ox.ac.uk

The most recent tabulations of nuclear magnetic dipole and electric quadrupole moments have been prepared and published by the Nuclear Data Section of the IAEA, Vienna [N. J. Stone, Report No. INDC(NDS)-0650 (2013); Report No. INDC(NDS)-0658 (2014)]. The first of these is a table of recommended quadrupole moments for all isotopes in which all experimental results are made consistent with a limited number of adopted standards for each element; the second is a combined listing of all measurements of both moments. Both tables cover all isotopes and energy levels. In this paper, the considerations relevant to the preparation of bothmore » tables are described, together with observations as to the importance and (where appropriate) application of necessary corrections to achieve the “best” values. Some discussion of experimental methods is included with emphasis on their precision. The aim of the published quadrupole moment table is to provide a standard reference in which the value given for each moment is the best available and for which full provenance is given. A table of recommended magnetic dipole moments is in preparation, with the same objective in view.« less

Preparation, validation and user-testing of pictogram-based patient information leaflets for hemodialysis patients.

PubMed

Mateti, Uday Venkat; Nagappa, Anantha Naik; Attur, Ravindra Prabhu; Bairy, Manohar; Nagaraju, Shankar Prasad; Mallayasamy, Surulivelrajan; Vilakkathala, Rajesh; Guddattu, Vasudev; Balkrishnan, Rajesh

2015-11-01

Patient information leaflets are universally-accepted resources to educate the patients/users about their medications, disease and lifestyle modification. The objective of the study was to prepare, validate and perform user-testing of pictogram-based patient information leaflets (P-PILs) among hemodialysis (HD) patients. The P-PILs are prepared by referring to the primary, secondary and tertiary resources. The content and pictograms of the leaflet have been validated by an expert committee consisting of three nephrologists and two academic pharmacists. The Baker Able Leaflet Design has been applied to develop the layout and design of the P-PILs. Quasi-experimental pre- and post-test design without control group was conducted on 81 HD patients for user-testing of P-PILs. The mean Baker Able Leaflet Design assessment score for English version of the leaflet was 28, and 26 for Kannada version. The overall user-testing knowledge assessment mean scores were observed to have significantly improved from 44.25 to 69.62 with p value <0.001. The overall user opinion of content and legibility of the leaflets was good. Pictogram-based patient information leaflets can be considered an effective educational tool for HD patients.

Ultra high frequency imaging acoustic microscope

DOEpatents

Deason, Vance A.; Telschow, Kenneth L.

2006-05-23

An imaging system includes: an object wavefront source and an optical microscope objective all positioned to direct an object wavefront onto an area of a vibrating subject surface encompassed by a field of view of the microscope objective, and to direct a modulated object wavefront reflected from the encompassed surface area through a photorefractive material; and a reference wavefront source and at least one phase modulator all positioned to direct a reference wavefront through the phase modulator and to direct a modulated reference wavefront from the phase modulator through the photorefractive material to interfere with the modulated object wavefront. The photorefractive material has a composition and a position such that interference of the modulated object wavefront and modulated reference wavefront occurs within the photorefractive material, providing a full-field, real-time image signal of the encompassed surface area.

Best Practices for Data Publication to Facilitate Integration into NED: A Reference Guide for Authors

NASA Astrophysics Data System (ADS)

Schmitz, Marion; Mazzarella, J. M.; Madore, B. F.; Ogle, P. M.; Ebert, R.; Baker, K.; Chan, H.; Chen, X.; Fadda, D.; Frayer, C.; Jacobson, J. D.; LaGue, C.; Lo, T. M.; Pevunova, O.; Terek, S.; Steer, I.

2014-01-01

At the urging of the NASA/IPAC Extragalactic Database (NED) Users Committee, the NED Team has prepared and published on its website a new document titled "Best Practices for Data Publication to Facilitate Integration into NED: A Reference Guide for Authors" (http://ned.ipac.caltech.edu/docs/BPDP/NED_BPDP.pdf). We hope that journal publishers will incorporate links to this living document in their Instructions to Authors to provide a practical reference for authors, referees, and science editors so as to help avoid various pitfalls that often impede the interpretation of data and metadata, and also delay their integration into NED, SIMBAD, ADS and other systems. In particular, we discuss the importance of using proper naming conventions, providing the epoch and system of coordinates, including units and uncertainties, and giving sufficient metadata for the unambiguous interpretation of tabular, imaging, and spectral data. The biggest impediments to the assimilation of new data from the literature into NED are ambiguous object names and non-unique, coordinate-based identifiers. A Checklist of Recommendations will be presented which includes links to sections of the Best Practices document that provide further examples, explanation, and rationale.

A.B.A. Checklist: Birds of Continental United States and Canada

USGS Publications Warehouse

Keith, G.S.; Balch, L.G.; Gibson, D.D.; McCaskie, R.G.; Robbins, C.S.; Small, A.; Sykes, P.W.; Tucker, J.A.

1982-01-01

The 'Summary' in this edition of the A BA Checklist has been greatly expanded to include all properly documented records for each accidental species. These records are published, except for a very few recent ones which are in press or in preparation. Emphasis is on records supported by specimens or photographs, but sight records are also included. To make these accounts more useful to researchers, a reference has been given for each record. All records, except those identified as '(photo)' or '(specimen)', or by some other type of objective evidence, are sight records. Because of the interest shown in this section of the Checklist, coverage has not been confined to accidental species (defined as those which have occurred fewer than ten times in the ABA Checklist area during the twentieth century). Accounts are also given for selected rare visitors and native species. Two of the primary references are abbreviated in the accounts: Audubon Field Notes-AFN, and American Birds-AB.

On a New Theory of the System of Reference

NASA Astrophysics Data System (ADS)

Kalanov, Temur Z.

2003-04-01

A new theory of the system of reference is suggested. It represents the new point of view which has arisen from the critical analysis of the foundations of physics (in particular, the theory of relativity and quantum mechanics), mathematics, cosmology and philosophy. The main idea following from the analysis is that the correct concept of system of reference represents a key to comprehension of many basic logic errors which are in modern physics. The starting point of the theory is represented by the philosophical (dialectical materialistic) principles, in particular, the gnosiological principle. (The gnosiological principle is briefly formulated as follows. The purpose of a science is to know the laws of the Nature. The law is a form of scientific knowledge of the essence and the phenomenon. The essence is the internal basis of the phenomenon, and the phenomenon is the manifestation of the essence. Human practice is a basis of knowledge and a criterion of truth). These principles lead to the following statements. (1) The reality is the dialectical unity of the opposites: the objective reality and the non-objective (subjective) reality. (2) The system mankind + means of knowledge belongs to the subjective reality and is called system of reference. In this wide sense, the system of reference is the universal informational gnostic basis (i.e. the system consisting of natural objects and processes, of constructed devices and instruments, of sum of human knowledge and skills) created and used by mankind for the purpose of knowledge of the world. (3) The opposites are bounds of each other. Hence, the principle of objectivity of the physical laws is formulated as follows: the objective physical laws must not contain mentions of system of reference (in particular, references to procedure of measurement or of calculation). (4) The main informational property of the unitary system set of researches physical objects + system of reference is that the system of reference determines (measures, calculates) the parameters of the subsystem set of researched physical objects (for example, the coordinates x_M, y_M, zM of the object M); the parameters characterize the system of reference (for example, the system of coordinates). (5) The main gnostic property of the unitary system set of researches physical objects + system of reference is that the system of reference defines (formulates) the physical laws (i.e. creates the theories); the physical laws characterize the system of reference. (6) The parameters which take on values independently of existence of the researched physical objects characterize the system of reference. For example, the clock C, a part of the system of reference S, determines (but it does not measure!) the time t_C; the time tC characterizes the clock C. If all clocks have been synchronized, the universal time tS characterizes the system of reference S. (7) Researched physical object M and a clock are mutually independent objects. Hence, the coordinates x_M, y_M, zM and the time tS are mutually independent parameters. (8) The informational one-to-one correspondence between motion of object M and physical clock-process in clock is established (is defined) by man. For example, it has a form: dx_M/dtS ≡ v_x_M. Consequences: (a) information about the world is an ordered information because the system of reference S is an ordered and universal system. This information is an objective one if it does not depend on a system of reference; (b) mathematical operations on physical quantities with the coordinates and with the time are allowed by the laws of logic because the set of researches physical objects + system of reference is a unitary system; (c) the principle of existence and of transformation of coordinates: there are no coordinates and no transformation of coordinates in general, and there exist the coordinates x_M, y_M, zM and transformation of the coordinates x_M, y_M, zM of the object M only; (d) the special and general theories of relativity are an erroneous theories because their foundations, firstly, do not satisfy the principle of objectivity of the physical laws, secondly, they contradict the principle of transformation of coordinates and, thirdly, they assume mutual dependence between the researched physical object and a clock (i.e. between coordinates and time); (e) quantum mechanics does not satisfy the principle of objectivity of the physical laws.

Multidimensional Analysis of Curved Root Canal Preparation Using Continuous or Reciprocating Nickel-titanium Instruments

PubMed Central

Mamede-Neto, Iussif; Borges, Álvaro Henrique; Alencar, Ana Helena Gonçalves; Duarte, Marco Antonio Hungaro; Sousa Neto, Manoel Damião; Estrela, Carlos

2018-01-01

Objective: To evaluate transportation (T) and centering ability (CA) of root canal preparations using continuous or reciprocating nickel-titanium endodontic files. Materials and Methods: Ninety-six mesiobuccal root canals of mandibular first and second molars were randomly divided into 6 groups (n=16) according to the rotary file used: 1. ProTaper Next; 2. ProTaper Gold; 3. Mtwo; 4. BioRaCe; 5. WaveOne Gold; 6. Reciproc. Root canals were prepared according to manufacturer’s instructions. Cone beam computed tomography scans were obtained before and after root canal preparation. Measurements were made at six different reference points: 2, 3 and 4 mm from the apex and 2, 3 and 4 mm below furcation in different directions. Results: The greatest Mesiodistal (MD) Transportation (T) was found for Reciproc files (p<0.05), and the greatest buccolingual (BL) T, for Reciproc, ProTaper Gold and ProTaper Next files (p<0.05). The greatest Mesiodistal (MD) Centering Ability (CA) was found for BioRaCe files (p<0.05), and the greatest Buccolingual (BL) CA, for BioRaCe and Mtwo files (p<0.05). Conclusion: All systems produced root canal transportation. No file system achieved perfect CA of root preparation. Reciproc files had the greatest MD T and BL T. BioRaCe files had the greatest MD CA, whereas BL CA was similar for BioRaCe and Mtwo files. PMID:29456772

Food adulteration analysis without laboratory prepared or determined reference food adulterant values.

PubMed

Kalivas, John H; Georgiou, Constantinos A; Moira, Marianna; Tsafaras, Ilias; Petrakis, Eleftherios A; Mousdis, George A

2014-04-01

Quantitative analysis of food adulterants is an important health and economic issue that needs to be fast and simple. Spectroscopy has significantly reduced analysis time. However, still needed are preparations of analyte calibration samples matrix matched to prediction samples which can be laborious and costly. Reported in this paper is the application of a newly developed pure component Tikhonov regularization (PCTR) process that does not require laboratory prepared or reference analysis methods, and hence, is a greener calibration method. The PCTR method requires an analyte pure component spectrum and non-analyte spectra. As a food analysis example, synchronous fluorescence spectra of extra virgin olive oil samples adulterated with sunflower oil is used. Results are shown to be better than those obtained using ridge regression with reference calibration samples. The flexibility of PCTR allows including reference samples and is generic for use with other instrumental methods and food products. Copyright © 2013 Elsevier Ltd. All rights reserved.

Characterization of the reference wave in a compact digital holographic camera.

PubMed

Park, I S; Middleton, R J C; Coggrave, C R; Ruiz, P D; Coupland, J M

2018-01-01

A hologram is a recording of the interference between an unknown object wave and a coherent reference wave. Providing the object and reference waves are sufficiently separated in some region of space and the reference beam is known, a high-fidelity reconstruction of the object wave is possible. In traditional optical holography, high-quality reconstruction is achieved by careful reillumination of the holographic plate with the exact same reference wave that was used at the recording stage. To reconstruct high-quality digital holograms the exact parameters of the reference wave must be known mathematically. This paper discusses a technique that obtains the mathematical parameters that characterize a strongly divergent reference wave that originates from a fiber source in a new compact digital holographic camera. This is a lensless design that is similar in principle to a Fourier hologram, but because of the large numerical aperture, the usual paraxial approximations cannot be applied and the Fourier relationship is inexact. To characterize the reference wave, recordings of quasi-planar object waves are made at various angles of incidence using a Dammann grating. An optimization process is then used to find the reference wave that reconstructs a stigmatic image of the object wave regardless of the angle of incidence.

Careers in science and technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The objective of this book is to expose junior and senior high school students to the science and technology fields. It also will convey the importance of getting a general education in science and mathematics while still in high school and of continuing such studies in college. This is intended to encourge students, particularly underrepresented minorities and women, to consider and prepare for careers in science and technology. This book attempts to point out the increasing importance of such knowledge in daily life regardless of occupational choice. This book is intended to be used by junior and senior high schoolmore » students, as a classroom reference by teachers, and by scientist and engineers participating in outreach activities.« less

The influence of objectives, learning experiences and examination blueprint on medical students' examination preparation

PubMed Central

McLaughlin, K; Coderre, S; Woloschuk, W; Lim, T; Muruve, D; Mandin, H

2005-01-01

Background The influence of intended and informal curricula on examination preparation has not been extensively studied. This study aims to firstly describe how students utilized components of intended and informal curricula to guide examination preparation, and secondly to study the relationship between examination preparation and performance. Methods Students received a pre-examination questionnaire to identify components from the intended curriculum (objectives and examination blueprint), and informal curriculum (content emphasised during lectures and small groups), used during examination preparation. Multiple logistic regression was used to study the relationship between these variables and student performance (above versus at or below average). Results Eighty-one students participated. There was no difference in the proportions using the examination blueprint, content emphasised during lectures, and content emphasised during small groups (87 – 93%) but fewer students used objectives (35%, p < 0.001). Objectives use was associated with reduced odds of above average examination performance (adjusted odds ratio 0.27 [0.07, 0.97], p = 0.04). Conclusion When preparing for the renal course examination, students were influenced at least as much by the informal as the intended curriculum. Of the two intended curriculum components, the examination blueprint appeared to be more widely used than the course objectives. This decreased use of objectives on examination preparation did not appear to have a detrimental effect on student performance. PMID:16359554

Certification of caffeine reference material purity by ultraviolet/visible spectrophotometry and high-performance liquid chromatography with diode-array detection as two independent analytical methods.

PubMed

Shehata, A B; Rizk, M S; Rend, E A

2016-10-01

Caffeine reference material certified for purity is produced worldwide, but no research work on the details of the certification process has been published in the literature. In this paper, we report the scientific details of the preparation and certification of pure caffeine reference materials. Caffeine was prepared by extraction from roasted and ground coffee by dichloromethane after heating in deionized water mixed with magnesium oxide. The extract was purified, dried, and bottled in dark glass vials. Stratified random selection was applied to select a number of vials for homogeneity and stability studies, which revealed that the prepared reference material is homogeneous and sufficiently stable. Quantification of caffeine purity % was carried out using a calibrated UV/visible spectrophotometer and a calibrated high-performance liquid chromatography with diode-array detection method. The results obtained from both methods were combined to drive the certified value and its associated uncertainty. The certified value of the reference material purity was found to be 99.86% and its associated uncertainty was ±0.65%, which makes the candidate reference material a very useful calibrant in food and drug chemical analysis. Copyright © 2016. Published by Elsevier B.V.

Two-Year-Olds Use Pragmatic Cues to Differentiate Reference to Objects and Actions.

ERIC Educational Resources Information Center

Tomasello, Michael; Akhtar, Nameera

1995-01-01

Attempts to determine whether children can use social-pragmatic cues to determine "what kind" of referent, object, or action an adult intends to indicate with a novel word. Doubts that children assume that a novel word refers to whatever nameless object is present. Suggests that lexical acquisition rests fundamentally on children's…

Sex Differences in Object Manipulation in Wild Immature Chimpanzees (Pan troglodytes schweinfurthii) and Bonobos (Pan paniscus): Preparation for Tool Use?

PubMed

Koops, Kathelijne; Furuichi, Takeshi; Hashimoto, Chie; van Schaik, Carel P

2015-01-01

Sex differences in immatures predict behavioural differences in adulthood in many mammal species. Because most studies have focused on sex differences in social interactions, little is known about possible sex differences in 'preparation' for adult life with regards to tool use skills. We investigated sex and age differences in object manipulation in immature apes. Chimpanzees use a variety of tools across numerous contexts, whereas bonobos use few tools and none in foraging. In both species, a female bias in adult tool use has been reported. We studied object manipulation in immature chimpanzees at Kalinzu (Uganda) and bonobos at Wamba (Democratic Republic of Congo). We tested predictions of the 'preparation for tool use' hypothesis. We confirmed that chimpanzees showed higher rates and more diverse types of object manipulation than bonobos. Against expectation, male chimpanzees showed higher object manipulation rates than females, whereas in bonobos no sex difference was found. However, object manipulation by male chimpanzees was play-dominated, whereas manipulation types of female chimpanzees were more diverse (e.g., bite, break, carry). Manipulation by young immatures of both species was similarly dominated by play, but only in chimpanzees did it become more diverse with age. Moreover, in chimpanzees, object types became more tool-like (i.e., sticks) with age, further suggesting preparation for tool use in adulthood. The male bias in object manipulation in immature chimpanzees, along with the late onset of tool-like object manipulation, indicates that not all (early) object manipulation (i.e., object play) in immatures prepares for subsistence tool use. Instead, given the similarity with gender differences in human children, object play may also function in motor skill practice for male-specific behaviours (e.g., dominance displays). In conclusion, even though immature behaviours almost certainly reflect preparation for adult roles, more detailed future work is needed to disentangle possible functions of object manipulation during development.

Solving multi-objective optimization problems in conservation with the reference point method

PubMed Central

Dujardin, Yann; Chadès, Iadine

2018-01-01

Managing the biodiversity extinction crisis requires wise decision-making processes able to account for the limited resources available. In most decision problems in conservation biology, several conflicting objectives have to be taken into account. Most methods used in conservation either provide suboptimal solutions or use strong assumptions about the decision-maker’s preferences. Our paper reviews some of the existing approaches to solve multi-objective decision problems and presents new multi-objective linear programming formulations of two multi-objective optimization problems in conservation, allowing the use of a reference point approach. Reference point approaches solve multi-objective optimization problems by interactively representing the preferences of the decision-maker with a point in the criteria (objectives) space, called the reference point. We modelled and solved the following two problems in conservation: a dynamic multi-species management problem under uncertainty and a spatial allocation resource management problem. Results show that the reference point method outperforms classic methods while illustrating the use of an interactive methodology for solving combinatorial problems with multiple objectives. The method is general and can be adapted to a wide range of ecological combinatorial problems. PMID:29293650

Getting the Picture: Iconicity Does Not Affect Representation-Referent Confusion

PubMed Central

Wimmer, Marina C.; Robinson, Elizabeth J.; Koenig, Laura; Corder, Emma

2014-01-01

Three experiments examined 3- to 5-year-olds' (N = 428) understanding of the relationship between pictorial iconicity (photograph, colored drawing, schematic drawing) and the real world referent. Experiments 1 and 2 explored pictorial iconicity in picture-referent confusion after the picture-object relationship has been established. Pictorial iconicity had no effect on referential confusion when the referent changed after the picture had been taken/drawn (Experiment 1) and when the referent and the picture were different from the outset (Experiment 2). Experiment 3 investigated whether children are sensitive to iconicity to begin with. Children deemed photographs from a choice of varying iconicity representations as best representations for object reference. Together, findings suggest that iconicity plays a role in establishing a picture-object relation per se but is irrelevant once children have accepted that a picture represents an object. The latter finding may reflect domain general representational abilities. PMID:25247708

Spatial Updating According to a Fixed Reference Direction of a Briefly Viewed Layout

ERIC Educational Resources Information Center

Zhang, Hui; Mou, Weimin; McNamara, Timothy P.

2011-01-01

Three experiments examined the role of reference directions in spatial updating. Participants briefly viewed an array of five objects. A non-egocentric reference direction was primed by placing a stick under two objects in the array at the time of learning. After a short interval, participants detected which object had been moved at a novel view…

[Studies on the identification of psychotropic substances. VIII. Preparation and various analytical data of reference standard of some stimulants, amfepramone, cathinone, N-ethylamphetamine, fenethylline, fenproporex and mefenorex].

PubMed

Shimamine, M; Takahashi, K; Nakahara, Y

1992-01-01

The Reference Standards for amfepramone, cathinone, N-ethylamphetamine, fenethylline, fenproporex and mefenorex were prepared. Their purities determined by HPLC were more than 99.5%. For the identification and determination of these six drugs, their analytical data were measured and discussed by TLC, UV, IR, HPLC, GC/MS and NMR.

Preceiving Patterns of Reference Service: A Survey

ERIC Educational Resources Information Center

Blakely, Florence

1971-01-01

Reference librarians must, if they hope to survive, retool in preparation for becoming the interface between the patron and computer-based information systems. This involves sharpening the interview technique and understanding where to plug into the information flow process. (4 references) (Author)

Self-Supporting, Hydrophobic, Ionic Liquid-Based Reference Electrodes Prepared by Polymerization-Induced Microphase Separation.

PubMed

Chopade, Sujay A; Anderson, Evan L; Schmidt, Peter W; Lodge, Timothy P; Hillmyer, Marc A; Bühlmann, Philippe

2017-10-27

Interfaces of ionic liquids and aqueous solutions exhibit stable electrical potentials over a wide range of aqueous electrolyte concentrations. This makes ionic liquids suitable as bridge materials that separate in electroanalytical measurements the reference electrode from samples with low and/or unknown ionic strengths. However, methods for the preparation of ionic liquid-based reference electrodes have not been explored widely. We have designed a convenient and reliable synthesis of ionic liquid-based reference electrodes by polymerization-induced microphase separation. This technique allows for a facile, single-pot synthesis of ready-to-use reference electrodes that incorporate ion conducting nanochannels filled with either 1-octyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide or 1-dodecyl-3-methylimidazolium bis(trifluoromethyl sulfonyl)imide as ionic liquid, supported by a mechanically robust cross-linked polystyrene phase. This synthesis procedure allows for the straightforward design of various reference electrode geometries. These reference electrodes exhibit a low resistance as well as good reference potential stability and reproducibility when immersed into aqueous solutions varying from deionized, purified water to 100 mM KCl, while requiring no correction for liquid junction potentials.

Preparation of canine C-reactive protein serum reference material: A feasibility study.

PubMed

Canalias, Francesca; Piñeiro, Matilde; Pato, Raquel; Peña, Raquel; Bosch, Lluís; Soler, Lourdes; García, Natalia; Lampreave, Fermín; Saco, Yolanda; Bassols, Anna

2018-03-01

The availability of a species-specific reference material is essential for the harmonization of results obtained in different laboratories by different methods. We describe the preparation of a canine C-reactive protein (cCRP) serum reference material containing purified cCRP stabilized in a serum matrix. The material can be used by manufacturers to assign values to their calibrator and control materials. The serum matrix was obtained using blood collected from healthy dogs, stabilized and submitted for a delipidation process. The reference material was prepared by diluting purified cCRP in the serum matrix containing 1.0 mol/L HEPES buffer, 3.0 mmol/L calcium chloride, 80,000 kUI/L aprotinin, and 1.0 mmol/L benzamidine hydrochloride monohydrate at a pH of 7.2, and dispensing (0.5 mL) the matrix into vials that were then frozen. The pilot batch of 200 vials was shown to be homogeneous and stable after a stability study at various temperatures and over a total time of 110 days. The prepared material was submitted to an assignment value study. Eight laboratories from different European countries participated by using the same reagents for an immunoturbidimetric method adapted for different analyzers. The obtained cCRP concentration in the reference material was 78.5 mg/L with an expanded uncertainty (k = 2) of 4.2 mg/L. Canine C-reactive protein serum reference material has been produced that allows harmonization of results obtained by different methods and different laboratories, thus reducing the possibility of errors and misunderstandings. © 2018 American Society for Veterinary Clinical Pathology.

32 CFR 1290.1 - References.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false References. 1290.1 Section 1290.1 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS PREPARING AND PROCESSING MINOR OFFENSES AND VIOLATION NOTICES REFERRED TO U.S. DISTRICT COURTS § 1290.1...

32 CFR 1290.1 - References.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false References. 1290.1 Section 1290.1 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS PREPARING AND PROCESSING MINOR OFFENSES AND VIOLATION NOTICES REFERRED TO U.S. DISTRICT COURTS § 1290.1...

32 CFR 1290.1 - References.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false References. 1290.1 Section 1290.1 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS PREPARING AND PROCESSING MINOR OFFENSES AND VIOLATION NOTICES REFERRED TO U.S. DISTRICT COURTS § 1290.1...

32 CFR 1290.1 - References.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false References. 1290.1 Section 1290.1 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS PREPARING AND PROCESSING MINOR OFFENSES AND VIOLATION NOTICES REFERRED TO U.S. DISTRICT COURTS § 1290.1...

32 CFR 1290.1 - References.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false References. 1290.1 Section 1290.1 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS PREPARING AND PROCESSING MINOR OFFENSES AND VIOLATION NOTICES REFERRED TO U.S. DISTRICT COURTS § 1290.1...

Out of Reach, Out of Mind? Infants' Comprehension of References to Hidden Inaccessible Objects.

PubMed

Osina, Maria A; Saylor, Megan M; Ganea, Patricia A

2017-09-01

This study investigated the nature of infants' difficulty understanding references to hidden inaccessible objects. Twelve-month-old infants (N = 32) responded to the mention of objects by looking at, pointing at, or approaching them when the referents were visible or accessible, but not when they were hidden and inaccessible (Experiment I). Twelve-month-olds (N = 16) responded robustly when a container with the hidden referent was moved from a previously inaccessible position to an accessible position before the request, but failed to respond when the reverse occurred (Experiment II). This suggests that infants might be able to track the hidden object's dislocations and update its accessibility as it changes. Knowing the hidden object is currently inaccessible inhibits their responding. Older, 16-month-old (N = 17) infants' performance was not affected by object accessibility. © 2016 The Authors. Child Development © 2016 Society for Research in Child Development, Inc.

The company objects keep: Linking referents together during cross-situational word learning.

PubMed

Zettersten, Martin; Wojcik, Erica; Benitez, Viridiana L; Saffran, Jenny

2018-04-01

Learning the meanings of words involves not only linking individual words to referents but also building a network of connections among entities in the world, concepts, and words. Previous studies reveal that infants and adults track the statistical co-occurrence of labels and objects across multiple ambiguous training instances to learn words. However, it is less clear whether, given distributional or attentional cues, learners also encode associations amongst the novel objects. We investigated the consequences of two types of cues that highlighted object-object links in a cross-situational word learning task: distributional structure - how frequently the referents of novel words occurred together - and visual context - whether the referents were seen on matching backgrounds. Across three experiments, we found that in addition to learning novel words, adults formed connections between frequently co-occurring objects. These findings indicate that learners exploit statistical regularities to form multiple types of associations during word learning.

Reference Accuracy among Research Articles Published in "Research on Social Work Practice"

ERIC Educational Resources Information Center

Wilks, Scott E.; Geiger, Jennifer R.; Bates, Samantha M.; Wright, Amy L.

2017-01-01

Objective: The objective was to examine reference errors in research articles published in Research on Social Work Practice. High rates of reference errors in other top social work journals have been noted in previous studies. Methods: Via a sampling frame of 22,177 total references among 464 research articles published in the previous decade, a…

Competition between multiple words for a referent in cross-situational word learning

PubMed Central

Benitez, Viridiana L.; Yurovsky, Daniel; Smith, Linda B.

2016-01-01

Three experiments investigated competition between word-object pairings in a cross-situational word-learning paradigm. Adults were presented with One-Word pairings, where a single word labeled a single object, and Two-Word pairings, where two words labeled a single object. In addition to measuring learning of these two pairing types, we measured competition between words that refer to the same object. When the word-object co-occurrences were presented intermixed in training (Experiment 1), we found evidence for direct competition between words that label the same referent. Separating the two words for an object in time eliminated any evidence for this competition (Experiment 2). Experiment 3 demonstrated that adding a linguistic cue to the second label for a referent led to different competition effects between adults who self-reported different language learning histories, suggesting both distinctiveness and language learning history affect competition. Finally, in all experiments, competition effects were unrelated to participants’ explicit judgments of learning, suggesting that competition reflects the operating characteristics of implicit learning processes. Together, these results demonstrate that the role of competition between overlapping associations in statistical word-referent learning depends on time, the distinctiveness of word-object pairings, and language learning history. PMID:27087742

Preparation and certification of arsenate [As(V)] reference material, NMIJ CRM 7912-a.

PubMed

Narukawa, Tomohiro; Kuroiwa, Takayoshi; Narushima, Izumi; Jimbo, Yasujiro; Suzuki, Toshihiro; Chiba, Koichi

2010-05-01

Arsenate [As(V)] solution reference material, National Metrology Institute of Japan (NMIJ) certified reference material (CRM) 7912-a, for speciation of arsenic species was developed and certified by NMIJ, the National Institute of Advanced Industrial Science and Technology. High-purity As(2)O(3) reagent powder was dissolved in 0.8 M HNO(3) solution and As(III) was oxidized to As(V) with HNO(3) to prepare 100 mg kg(-1) of As(V) candidate CRM solution. The solution was bottled in 400 bottles (50 mL each). The concentration of As(V) was determined by four independent analytical techniques-inductively coupled plasma mass spectrometry, inductively coupled plasma optical emission spectrometry, graphite furnace atomic absorption spectrometry, and liquid chromatography inductively coupled plasma mass spectrometry-according to As(V) calibration solutions, which were prepared from the arsenic standard of the Japan Calibration Service system and whose species was guaranteed to be As(V) by NMIJ. The uncertainties of all the measurements and preparation procedures were evaluated. The certified value of As(V) in the CRM is (99.53 +/- 1.67) mg kg(-1) (k = 2).

Radiochemistry of iodine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kahn, M.; Kleinberg, J.

1977-09-01

The preparation of isotopes of the element, with selected procedures for its determination in or separation from various media is described along with the separating of iodine species from each other. Each part of the introductory section is referenced separately from the remainder of the monograph. For the preparative and analytical sections there is an extensive, indexed bibliography which was developed from the indexes of Volumes 19 to 30 inclusive (1965-1974) of Nuclear Science Abstracts (NSA). From these indexes the NSA abstracts of possible pertinent references were selected for examination and a choice was made of those references which weremore » to be included in the bibliography. The bibliography has both primary and secondary references. Although the monograph does not cover hot atom chemistry, the kinetics of exchange reactions, decay schemes, or physiological applications, papers in these areas were examined as possible sources of useful preparative and analytical procedures. (JRD)« less

[Standard sample preparation method for quick determination of trace elements in plastic].

PubMed

Yao, Wen-Qing; Zong, Rui-Long; Zhu, Yong-Fa

2011-08-01

Reference sample was prepared by masterbatch method, containing heavy metals with known concentration of electronic information products (plastic), the repeatability and precision were determined, and reference sample preparation procedures were established. X-Ray fluorescence spectroscopy (XRF) analysis method was used to determine the repeatability and uncertainty in the analysis of the sample of heavy metals and bromine element. The working curve and the metrical methods for the reference sample were carried out. The results showed that the use of the method in the 200-2000 mg x kg(-1) concentration range for Hg, Pb, Cr and Br elements, and in the 20-200 mg x kg(-1) range for Cd elements, exhibited a very good linear relationship, and the repeatability of analysis methods for six times is good. In testing the circuit board ICB288G and ICB288 from the Mitsubishi Heavy Industry Company, results agreed with the recommended values.

Two-year-olds exclude novel objects as potential referents of novel words based on pragmatics.

PubMed

Grassmann, Susanne; Stracke, Marén; Tomasello, Michael

2009-09-01

Many studies have established that children tend to exclude objects for which they already have a name as potential referents of novel words. In the current study we asked whether this exclusion can be triggered by social-pragmatic context alone without pre-existing words as blockers. Two-year-old children watched an adult looking at a novel object while saying a novel word with excitement. In one condition the adult had not seen the object beforehand, and so the children interpreted the adult's utterance as referring to the gazed-at object. In another condition the adult and child had previously played jointly with the gazed-at object. In this case, children less often assumed that the adult was referring to the object but rather they searched for an alternative referent--presumably because they inferred that the gazed-at object was old news in their common ground with the adult and so not worthy of excited labeling. Since this inference based on exclusion is highly similar to that underlying the Principle of Contrast/Mutual Exclusivity, we propose that this principle is not purely lexical but rather is based on children's understanding of how and why people direct one another's attention to things either with or without language.

Preparation of an in-house reference material containing fumonisins in Thai rice and matrix extension of the analytical method for Japanese rice.

PubMed

Awaludin, Norhafniza; Nagata, Reiko; Kawasaki, Tomomi; Kushiro, Masayo

2009-12-01

Mycotoxin contamination in rice is less reported, compared to that in wheat or maize, however, some Fusarium fungi occasionally infect rice in the paddy field. Fumonisins are mycotoxins mainly produced by Fusarium verticillioides, which often ruins maize. Rice adherent fungus Gibberella fujikuroi is taxonomically near to F. verticillioides, and there are sporadic reports of fumonisin contamination in rice from Asia, Europe and the United States. Therefore, there exists the potential risk of fumonisin contamination in rice as well as the need for the validated analytical method for fumonisins in rice. Although both natural and spiked reference materials are available for some Fusarium mycotoxins in matrices of wheat and maize, there are no reference materials for Fusarium mycotoxins in rice. In this study, we have developed a method for the preparation of a reference material containing fumonisins in Thai rice. A ShakeMaster grinding machine was used for the preparation of a mixed material of blank Thai rice and F. verticillioides-infected Thai rice. The homogeneity of the mixed material was confirmed by one-way analysis of variance, which led this material to serve as an in-house reference material. Using this reference material, several procedures to extract fumonisins from Thai rice were compared. Accordingly, we proved the applicability of an effective extraction procedure for the determination of fumonisins in Japanese rice.

Preparation of an In-House Reference Material Containing Fumonisins in Thai Rice and Matrix Extension of the Analytical Method for Japanese Rice

PubMed Central

Awaludin, Norhafniza; Nagata, Reiko; Kawasaki, Tomomi; Kushiro, Masayo

2009-01-01

Mycotoxin contamination in rice is less reported, compared to that in wheat or maize, however, some Fusarium fungi occasionally infect rice in the paddy field. Fumonisins are mycotoxins mainly produced by Fusarium verticillioides, which often ruins maize. Rice adherent fungus Gibberella fujikuroi is taxonomically near to F. verticillioides, and there are sporadic reports of fumonisin contamination in rice from Asia, Europe and the United States. Therefore, there exists the potential risk of fumonisin contamination in rice as well as the need for the validated analytical method for fumonisins in rice. Although both natural and spiked reference materials are available for some Fusarium mycotoxins in matrices of wheat and maize, there are no reference materials for Fusarium mycotoxins in rice. In this study, we have developed a method for the preparation of a reference material containing fumonisins in Thai rice. A ShakeMaster grinding machine was used for the preparation of a mixed material of blank Thai rice and F. verticillioides-infected Thai rice. The homogeneity of the mixed material was confirmed by one-way analysis of variance, which led this material to serve as an in-house reference material. Using this reference material, several procedures to extract fumonisins from Thai rice were compared. Accordingly, we proved the applicability of an effective extraction procedure for the determination of fumonisins in Japanese rice. PMID:22069540

The integration of Human Factors (HF) in the SAR process training course text

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryan, T.G.

1995-03-01

This text provides the technical basis for a two-day course on human factors (HF), as applied to the Safety Analysis Report (SAR) process. The overall objective of this text and course is to: provide the participant with a working knowledge of human factors-related requirements, suggestions for doing a human safety analysis applying a graded approach, and an ability to demonstrate using the results of the human safety analysis, that human factors elements as defined by DOE (human factors engineering, procedures, training, oversight, staffing, qualifications), can support wherever necessary, nuclear safety commitments in the SAR. More specifically, the objectives of themore » text and course are: (1) To provide the SAR preparer with general guidelines for doing HE within the context of a graded approach for the SAR; (2) To sensitize DOE facility managers and staff, safety analysts and SAR preparers, independent reviewers, and DOE reviewers and regulators, to DOE Order 5480.23 requirements for HE in the SAR; (3) To provide managers, analysts, reviewers and regulators with a working knowledge of HE concepts and techniques within the context of a graded approach for the SAR, and (4) To provide SAR managers and DOE reviewers and regulators with general guidelines for monitoring and coordinating the work of preparers of HE inputs throughout the SAR process, and for making decisions regarding the safety relevance of HE inputs to the SAR. As a ready reference for implementing the human factors requirements of DOE Order 5480.22 and DOE Standard 3009-94, this course text and accompanying two-day course are intended for all persons who are involved in the SAR.« less

Biosensor technology for the detection of illegal drugs I: objectives, preparatory work, and drug enrichment

NASA Astrophysics Data System (ADS)

Hilpert, Reinhold; Binder, Florian; Grol, Michael; Hallermayer, Klaus; Josel, Hans-Peter; Klein, Christian; Maier, Josef; Oberpriller, Helmut; Ritter, Josef; Scheller, Frieder W.

1994-10-01

In a joint project of Deutsche Aerospace, Boehringer Mannheim and the University of Potsdam portable devices for the detection of illegal drugs, based on biosensor technology, are being developed. The concept enrichment of the drug from the gas phase and detection by immunological means. This publication covers the description of our objectives, preparatory work and results concerning enrichment of drugs from the gas phase. Vapor pressures of cocaine and cannabinoids have been determined. A test gas generator has been constructed which allows for reproducible preparation of cocaine concentrations between 2 ng/l and 2 pg/l. Coupling of a thermodesorption unit with GC/MS has been established for reference analysis. As another analytical tool, an ELISA with a lower detection limit of about 0,5 pg cocaine/assay has been developed. Applying fleece-type adsorbers, enrichment factors for cocaine in the range of 105 have been realized. No significant interference was found with potentially disturbing substances.

Defining the cortical visual systems: "what", "where", and "how"

NASA Technical Reports Server (NTRS)

Creem, S. H.; Proffitt, D. R.; Kaiser, M. K. (Principal Investigator)

2001-01-01

The visual system historically has been defined as consisting of at least two broad subsystems subserving object and spatial vision. These visual processing streams have been organized both structurally as two distinct pathways in the brain, and functionally for the types of tasks that they mediate. The classic definition by Ungerleider and Mishkin labeled a ventral "what" stream to process object information and a dorsal "where" stream to process spatial information. More recently, Goodale and Milner redefined the two visual systems with a focus on the different ways in which visual information is transformed for different goals. They relabeled the dorsal stream as a "how" system for transforming visual information using an egocentric frame of reference in preparation for direct action. This paper reviews recent research from psychophysics, neurophysiology, neuropsychology and neuroimaging to define the roles of the ventral and dorsal visual processing streams. We discuss a possible solution that allows for both "where" and "how" systems that are functionally and structurally organized within the posterior parietal lobe.

Circular common-path point diffraction interferometer.

PubMed

Du, Yongzhao; Feng, Guoying; Li, Hongru; Vargas, J; Zhou, Shouhuan

2012-10-01

A simple and compact point-diffraction interferometer with circular common-path geometry configuration is developed. The interferometer is constructed by a beam-splitter, two reflection mirrors, and a telescope system composed by two lenses. The signal and reference waves travel along the same path. Furthermore, an opaque mask containing a reference pinhole and a test object holder or test window is positioned in the common focal plane of the telescope system. The object wave is divided into two beams that take opposite paths along the interferometer. The reference wave is filtered by the reference pinhole, while the signal wave is transmitted through the object holder. The reference and signal waves are combined again in the beam-splitter and their interference is imaged in the CCD. The new design is compact, vibration insensitive, and suitable for the measurement of moving objects or dynamic processes.

Urban Mass Transportation.

ERIC Educational Resources Information Center

Mervine, K. E.

This bibliography is part of a series of Environmental Resource Packets prepared under a grant from EXXON Education Foundation. The most authoritative and accessible references in the urban transportation field are reviewed. The authors, publisher, point of view, level, and summary are given for each reference. The references are categorized…

Automatic Recognition of Object Names in Literature

NASA Astrophysics Data System (ADS)

Bonnin, C.; Lesteven, S.; Derriere, S.; Oberto, A.

2008-08-01

SIMBAD is a database of astronomical objects that provides (among other things) their bibliographic references in a large number of journals. Currently, these references have to be entered manually by librarians who read each paper. To cope with the increasing number of papers, CDS develops a tool to assist the librarians in their work, taking advantage of the Dictionary of Nomenclature of Celestial Objects, which keeps track of object acronyms and of their origin. The program searches for object names directly in PDF documents by comparing the words with all the formats stored in the Dictionary of Nomenclature. It also searches for variable star names based on constellation names and for a large list of usual names such as Aldebaran or the Crab. Object names found in the documents often correspond to several astronomical objects. The system retrieves all possible matches, displays them with their object type given by SIMBAD, and lets the librarian make the final choice. The bibliographic reference can then be automatically added to the object identifiers in the database. Besides, the systematic usage of the Dictionary of Nomenclature, which is updated manually, permitted to automatically check it and to detect errors and inconsistencies. Last but not least, the program collects some additional information such as the position of the object names in the document (in the title, subtitle, abstract, table, figure caption...) and their number of occurrences. In the future, this will permit to calculate the 'weight' of an object in a reference and to provide SIMBAD users with an important new information, which will help them to find the most relevant papers in the object reference list.

Subclinical delusional ideation and a self-reference bias in everyday reasoning.

PubMed

Galbraith, Niall; Manktelow, Ken; Morris, Neil

2008-02-01

Previous studies (e.g. Moller & Husby, 2000; Blackwood et al., 2004) have revealed that delusional thinking is accompanied by an exaggerated focus upon the self and upon stimuli that are perceived to be related to the self. The objective was to examine whether those high in subclinical delusional ideation exhibit a heightened tendency for self-reference. Using a mixed design, healthy individuals, classified into high- and low-scoring groups on the Peters et al. Delusions Inventory (Peters, Day, & Garety, 1996), were compared on everyday reasoning tasks across three experiments. High-PDI scorers, in contrast to the low-PDI group, rated self-referent objections to everyday arguments as stronger than other-referent objections and formulated more self-referent assertion-based objections to everyday arguments. The findings support the notion that subclinical delusional ideation is linked to a self-reference bias, which is evident in the sort of everyday thinking that people engage in when forming or evaluating their beliefs and which may contribute to delusion formation.

Global Lakes Sentinel Services: Water Quality Parameters Retrieval in Lakes Using the MERIS and S3-OLCI Band Sets

NASA Astrophysics Data System (ADS)

Peters, Steef; Alikas, Krista; Hommersom, Annelies; Latt, Silver; Reinart, Anu; Giardino, Claudia; Bresciani, Mariano; Philipson, Petra; Ruescas, Ana; Stelzer, Kerstin; Schenk, Karin; Heege, Thomas; Gege, Peter; Koponen, Sampsa; Kallio, Karri; Zhang, Yunlin

2015-12-01

The European collaborative project GLaSS aims to prepare for the use of the data streams from Sentinel 2 and Sentinel 3. Its focus is on inland waters, since these are considered to be sentinels for land-use- and climate change and need to be monitored closely. One of the objectives of the project is to compare existing water quality algorithms and parameterizations on the basis of in-situ spectral observations and Hydrolight simulations. A first achievement of the project is the collection of over 400 Rrs spectra with accompanying data on CHL, TSM, aCDOM and Secchi depth. Especially the dataset on Lake CDOM measurements represents a rather unique reference dataset.

Utilizing the PREPaRE Model When Multiple Classrooms Witness a Traumatic Event

ERIC Educational Resources Information Center

Bernard, Lisa J.; Rittle, Carrie; Roberts, Kathy

2011-01-01

This article presents an account of how the Charleston County School District responded to an event by utilizing the PREPaRE model (Brock, et al., 2009). The acronym, PREPaRE, refers to a range of crisis response activities: P (prevent and prepare for psychological trauma), R (reaffirm physical health and perceptions of security and safety), E…

Direct-to-digital holography and holovision

DOEpatents

Thomas, Clarence E.; Baylor, Larry R.; Hanson, Gregory R.; Rasmussen, David A.; Voelkl, Edgar; Castracane, James; Simkulet, Michelle; Clow, Lawrence

2000-01-01

Systems and methods for direct-to-digital holography are described. An apparatus includes a laser; a beamsplitter optically coupled to the laser; a reference beam mirror optically coupled to the beamsplitter; an object optically coupled to the beamsplitter, a focusing lens optically coupled to both the reference beam mirror and the object; and a digital recorder optically coupled to the focusing lens. A reference beam is incident upon the reference beam mirror at a non-normal angle, and the reference beam and an object beam are focused by the focusing lens at a focal plane of the digital recorder to form an image. The systems and methods provide advantages in that computer assisted holographic measurements can be made.

Virtual mask digital electron beam lithography

DOEpatents

Baylor, L.R.; Thomas, C.E.; Voelkl, E.; Moore, J.A.; Simpson, M.L.; Paulus, M.J.

1999-04-06

Systems and methods for direct-to-digital holography are described. An apparatus includes a laser; a beamsplitter optically coupled to the laser; a reference beam mirror optically coupled to the beamsplitter; an object optically coupled to the beamsplitter, a focusing lens optically coupled to both the reference beam mirror and the object; and a digital recorder optically coupled to the focusing lens. A reference beam is incident upon the reference beam mirror at a non-normal angle, and the reference beam and an object beam are focused by the focusing lens at a focal plane of the digital recorder to form an image. The systems and methods provide advantages in that computer assisted holographic measurements can be made. 5 figs.

Virtual mask digital electron beam lithography

DOEpatents

Baylor, Larry R.; Thomas, Clarence E.; Voelkl, Edgar; Moore, James A.; Simpson, Michael L.; Paulus, Michael J.

1999-01-01

Systems and methods for direct-to-digital holography are described. An apparatus includes a laser; a beamsplitter optically coupled to the laser; a reference beam mirror optically coupled to the beamsplitter; an object optically coupled to the beamsplitter, a focusing lens optically coupled to both the reference beam mirror and the object; and a digital recorder optically coupled to the focusing lens. A reference beam is incident upon the reference beam mirror at a non-normal angle, and the reference beam and an object beam are focused by the focusing lens at a focal plane of the digital recorder to form an image. The systems and methods provide advantages in that computer assisted holographic measurements can be made.

Collaborative study for the establishment of erythropoietin BRP batch 4.

PubMed

Burns, C; Bristow, A F; Daas, A; Costanzo, A

2015-01-01

The European Pharmacopoeia (Ph. Eur.) Biological Reference Preparation (BRP) for erythropoietin (EPO) is used as a working standard for potency determination of EPO preparations by in vivo bioassay as prescribed in the Ph. Eur. monograph Erythropoietin concentrated solution (1316). The BRP batch 3 was calibrated in 2006 and its stocks are depleted. The European Directorate for the Quality of Medicines & HealthCare (EDQM) thus initiated a project to calibrate a replacement batch in International Units against the WHO 3(rd) International Standard (IS) for Erythropoietin, recombinant, for bioassay (11/170). A Ph. Eur. Chemical Reference Substance (CRS) was established recently for use as reference in some of the physicochemical tests prescribed in the monograph. Therefore, the EPO BRP batch 4 was only calibrated for the normocythaemic and polycythaemic mouse in vivo bioassays described in the Assay section of the Ph. Eur. monograph (1316). The collaborative study involved seven laboratories from Europe, the USA and South America. The results confirmed that the candidate BRP (cBRP) is suitable for use as a reference preparation in the potency determination of EPO medicinal products by bioassay (using the normocythaemic or polycythaemic mouse methods). The outcome of the study enabled the Ph. Eur. Commission to establish the proposed standard as erythropoietin BRP batch 4 in November 2014 for use as a reference preparation solely for the polycythaemic and normocythaemic mouse bioassay, with an assigned potency of 13 000 IU/vial. Furthermore, the potency of BRP3 was confirmed during the study, thus warranting a good continuity of the IU.

The OIE World Animal Health Information System: the role of OIE Reference Laboratories and Collaborating Centres in disease reporting.

PubMed

Ben Jebara, K

2010-12-01

One of the main objectives of the World Organisation for Animal Health (OIE) is to ensure transparency in and knowledge of the world animal health situation. To achieve this objective, the OIE relies on its network of Member Countries, which is complemented by the activities of 221 Reference Laboratories (RLs) and Collaborating Centres. The RL mandate states that, in the case of positive results for diseases notifiable to the OIE, the laboratory should inform the OIE Delegate of the Member Country from which the samples originated and send a copy of the information to OIE Headquarters. However, since 2006 the OIE has received a lower than expected number of notifications from RLs, which implies eitherthat the majority of samples are sent to national laboratories or that some RLs are not fully complying with their mandate. The OIE sent a questionnaire to RLs in preparation for the Second Global Conference of OIE Reference Laboratories and Collaborating Centres (Paris, France, 21-23 June 2010). Two main factors emerged: the need for RLs to clarify their role and responsibilities in disease reporting and the need for an awareness campaign to sensitise national Veterinary Services to the importance of conducting more surveillance (and consequently of submitting samples to RLs) for all OIE-listed diseases. Reference laboratories indicated two main reasons for not sharing more data on positive samples with the OIE: i) a perceived contradiction between their mandate as OIE RLs and the standards of the International Organization for Standardization (ISO) dealing with confidentiality; and ii) certain Member Countries or stakeholders asking RLs not to share positive results with the OIE, for political or economic reasons. The OIE has put forward proposals to help RLs resolve these problems in future. The use of ISO standards must be clarified and there must be improved communication between the OIE and its RLs. A lack of transparency about a significant disease event can jeopardise the biosecurity of several countries, an entire region or even the whole world. The reference status of a non-transparent RL could be questioned.

Comparing the accuracy (trueness and precision) of models of fixed dental prostheses fabricated by digital and conventional workflows.

PubMed

Sim, Ji-Young; Jang, Yeon; Kim, Woong-Chul; Kim, Hae-Young; Lee, Dong-Hwan; Kim, Ji-Hwan

2018-03-31

This study aimed to evaluate and compare the accuracy. A reference model was prepared with three prepared teeth for three types of restorations: single crown, 3-unit bridge, and inlay. Stone models were fabricated from conventional impressions. Digital impressions of the reference model were created using an intraoral scanner (digital models). Physical models were fabricated using a three-dimensional (3D) printer. Reference, stone, and 3D printed models were subsequently scanned using an industrial optical scanner; files were exported in a stereolithography file format. All datasets were superimposed using 3D analysis software to evaluate the accuracy of the complete arch and trueness of the preparations. One-way and two-way analyses of variance (ANOVA) were performed to compare the accuracy among the three model groups and evaluate the trueness among the three types of preparation. For the complete arch, significant intergroup differences in precision were observed for the three groups (p<.001). However, no significant difference in trueness was found between the stone and digital models (p>.05). 3D printed models had the poorest accuracy. A two-way ANOVA revealed significant differences in trueness among the model groups (p<.001) and types of preparation (p<.001). Digital models had smaller root mean square values of trueness of the complete arch and preparations than stone models. However, the accuracy of the complete arch and trueness of the preparations of 3D printed models were inferior to those of the other groups. Copyright © 2018 Japan Prosthodontic Society. Published by Elsevier Ltd. All rights reserved.

Self-Supporting, Hydrophobic, Ionic Liquid-Based Reference Electrodes Prepared by Polymerization-Induced Microphase Separation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chopade, Sujay A.; Anderson, Evan L.; Schmidt, Peter W.

Interfaces of ionic liquids and aqueous solutions exhibit stable electrical potentials over a wide range of aqueous electrolyte concentrations. This makes ionic liquids suitable as bridge materials that separate in electroanalytical measurements the reference electrode from samples with low and/or unknown ionic strengths. However, methods for the preparation of ionic liquid-based reference electrodes have not been explored widely. We have designed a convenient and reliable synthesis of ionic liquid-based reference electrodes by polymerization-induced microphase separation. This technique allows for a facile, single-pot synthesis of ready-to-use reference electrodes that incorporate ion conducting nanochannels filled with either 1-octyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide or 1-dodecyl-3-methylimidazolium bis(trifluoromethylmore » sulfonyl)imide as ionic liquid, supported by a mechanically robust cross-linked polystyrene phase. This synthesis procedure allows for the straightforward design of various reference electrode geometries. These reference electrodes exhibit a low resistance as well as good reference potential stability and reproducibility when immersed into aqueous solutions varying from deionized, purified water to 100 mM KCl, while requiring no correction for liquid junction potentials.« less

Reference Directions and Reference Objects in Spatial Memory of a Briefly Viewed Layout

ERIC Educational Resources Information Center

Mou, Weimin; Xiao, Chengli; McNamara, Timothy P.

2008-01-01

Two experiments investigated participants' spatial memory of a briefly viewed layout. Participants saw an array of five objects on a table and, after a short delay, indicated whether the target object indicated by the experimenter had been moved. Experiment 1 showed that change detection was more accurate when non-target objects were stationary…

NBS/EPA (NATIONAL BUREAU OF STANDARDS/ENVIRONMENTAL PROTECTION AGENCY) CERTIFIED REFERENCE MATERIAL PERFORMANCE AUDIT PROGRAM: STATUS REPORT 1

EPA Science Inventory

A traceability procedure has been established which allows specialty gas producers to prepare gaseous pollutant Certified Reference Materials (CRMs). The accuracy, stability and homogeneity of the CRMs approach those of NBS Standard Reference Materials (SRMs). Part of this proced...

NBS/EPA (NATIONAL BUREAU OF STANDARDS/ENVIRONMENTAL PROTECTION AGENCY) CERTIFIED REFERENCE MATERIAL PERFORMANCE AUDIT PROGRAM: STATUS REPORT 2

EPA Science Inventory

A traceability procedure has been established which allows specialty gas producers to prepare gaseous pollutant Certified Reference Materials (CRM's). The accuracy, stability and homogeneity of the CRM's approach those of NBS Standard Reference Materials (SRM's). As of October 19...

(Environmental investigation of ground water contamination at Wright-Patterson Air Force Base, Ohio)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-04-01

This Removal Action System Design has been prepared as a Phase I Volume for the implementation of the Phase II removal action at Wright-Patterson Air Force Base (WPAFB) near Dayton, Ohio. The objective of the removal action is to prevent, to the extent practicable, the migration of ground water contaminated with chlorinated volatile organic compounds (VOCS) across the southwest boundary of Area C. The Phase 1, Volume 9 Removal Action System Design compiles the design documents prepared for the Phase II Removal Action. These documents, which are presented in Appendices to Volume 9, include: Process Design, which presents the 30more » percent design for the ground water treatment system (GWTS); Design Packages 1 and 2 for Earthwork and Road Construction, and the Discharge Pipeline, respectively; no drawings are included in the appendix; Design Package 3 for installation of the Ground Water Extraction Well(s); Design Package 4 for installation of the Monitoring Well Instrumentation; and Design Package 5 for installation of the Ground Water Treatment System; this Design Package is incorporated by reference because of its size.« less

Screening and characterization of extracelluar L-asparaginase producing Bacillus subtilis strain hswx88, isolated from Taptapani hotspring of Odisha, India

PubMed Central

Pradhan, Biswaprakash; Dash, Sashi K; Sahoo, Sabuj

2013-01-01

Objective To screen and isolate an eco-friendly, a thermophilic and potent L-asparaginase producing bacterium, with novel immunological properties that may obviates hypersensitivity reactions. Methods In the present study bacterial strain isolated for extracellular L-asparaginase production from hotspring, identified by morphological, biochemical and physiological tests followed by 16S rDNA technology and the L-asparaginase production ability was tested by both semi quantitative and quantitative enzymatic assay. Result The bacterial strain was identified as Bacillus subtilis strain hswx88 (GenBank Accession Number: JQ237656.1). The extracellular enzyme yielding capacity isolate Bacillus subtilis strain hswx88 (23.8 IU/mL) was found to be 1.7 and 14.5 times higher than the reference organism Pectobacterium carotovorum MTCC 1428 (14.2 IU/mL) and Bacillus sp. BCCS 034 (1.64 IU/mL). Conclusion The isolate is eco-friendly and useful to produce bulk quantity of extracellular, thermophilic L-asparaginase for the treatment of various tumor cases and for preparation of acrylamide free fry food preparation. PMID:24093783

Establishment of a biological reference preparation for hepatitis A vaccine (inactivated, non-adsorbed).

PubMed

Stalder, J; Costanzo, A; Daas, A; Rautmann, G; Buchheit, K-H

2010-04-01

A reference standard calibrated in International Units (IU) is needed for the in vitro potency assay of hepatitis A vaccines prepared by formalin-inactivation of purified hepatitis A virus grown in cell cultures. Thus, a project was launched by the European Directorate for the Quality of Medicines & HealthCare (EDQM) to establish one or more non-adsorbed inactivated hepatitis A vaccine reference preparation(s) as working standard(s), calibrated against the 1st International Standard (IS), for the in vitro potency assay (ELISA) of all vaccines present on the European market. Four non-adsorbed liquid preparations of formalin-inactivated hepatitis A antigen with a known antigen content were obtained from 3 manufacturers as candidate Biological Reference Preparations (BRPs). Thirteen laboratories participated in the collaborative study. They were asked to use an in vitro ELISA method adapted from a commercially available kit for the detection of antibodies to hepatitis A virus. In-house validated assays were to be run in parallel, where available. Some participants also included commercially available hepatitis A vaccines in the assays, after appropriate desorption. During the collaborative study, several participants using the standard method were faced with problems with some of the most recent lots of the test kits. Due to these problems, the standard method did not perform satisfactorily and a high number of assays were invalid, whereas the in-house methods appeared to perform better. Despite this, the overall mean results of the valid assays using both methods were in agreement. Nonetheless, it was decided to base the assignment of the potency values on the in-house methods only. The results showed that all candidate BRPs were suitable for the intended purpose. However, based on availability of the material and on the results of end-product testing, 2 candidate reference preparations, Samples C and D, were selected. Both were from the same batch but filled on different days; no statistically significant difference in potency was observed. They were thus combined in 1 single batch. The candidate preparation (Sample C/D) was adopted at the June 2009 session of the European Pharmacopoeia (Ph. Eur.) Commission as the Ph. Eur. BRP batch 1 for hepatitis A vaccine (inactivated, non-adsorbed), with an assigned potency of 12 IU/ml for in vitro antigen content assays. Accelerated degradation studies have been initiated. The preliminary data show that the BRP is stable at the recommended storage temperature (< -50 degrees C). The BRP will be monitored at regular intervals throughout its lifetime.

Sex Differences in Object Manipulation in Wild Immature Chimpanzees (Pan troglodytes schweinfurthii) and Bonobos (Pan paniscus): Preparation for Tool Use?

PubMed Central

Koops, Kathelijne; Furuichi, Takeshi; Hashimoto, Chie; van Schaik, Carel P.

2015-01-01

Sex differences in immatures predict behavioural differences in adulthood in many mammal species. Because most studies have focused on sex differences in social interactions, little is known about possible sex differences in ‘preparation’ for adult life with regards to tool use skills. We investigated sex and age differences in object manipulation in immature apes. Chimpanzees use a variety of tools across numerous contexts, whereas bonobos use few tools and none in foraging. In both species, a female bias in adult tool use has been reported. We studied object manipulation in immature chimpanzees at Kalinzu (Uganda) and bonobos at Wamba (Democratic Republic of Congo). We tested predictions of the ‘preparation for tool use’ hypothesis. We confirmed that chimpanzees showed higher rates and more diverse types of object manipulation than bonobos. Against expectation, male chimpanzees showed higher object manipulation rates than females, whereas in bonobos no sex difference was found. However, object manipulation by male chimpanzees was play-dominated, whereas manipulation types of female chimpanzees were more diverse (e.g., bite, break, carry). Manipulation by young immatures of both species was similarly dominated by play, but only in chimpanzees did it become more diverse with age. Moreover, in chimpanzees, object types became more tool-like (i.e., sticks) with age, further suggesting preparation for tool use in adulthood. The male bias in object manipulation in immature chimpanzees, along with the late onset of tool-like object manipulation, indicates that not all (early) object manipulation (i.e., object play) in immatures prepares for subsistence tool use. Instead, given the similarity with gender differences in human children, object play may also function in motor skill practice for male-specific behaviours (e.g., dominance displays). In conclusion, even though immature behaviours almost certainly reflect preparation for adult roles, more detailed future work is needed to disentangle possible functions of object manipulation during development. PMID:26444011

Acquisition and replay systems for direct-to-digital holography and holovision

DOEpatents

Thomas, Clarence E.; Hanson, Gregory R.

2003-02-25

Improvements to the acquisition and replay systems for direct-to-digital holography and holovision are described. A method of recording an off-axis hologram includes: splitting a laser beam into an object beam and a reference beam; reflecting the reference beam from a reference beam mirror; reflecting the object beam from an illumination beamsplitter; passing the object beam through an objective lens; reflecting the object beam from an object; focusing the reference beam and the object beam at a focal plane of a digital recorder to form an off-axis hologram; digitally recording the off-axis hologram; and transforming the off-axis hologram in accordance with a Fourier transform to obtain a set of results. A method of writing an off-axis hologram includes: passing a laser beam through a spatial light modulator; and focusing the laser beam at a focal plane of a photorefractive crystal to impose a holographic diffraction grating pattern on the photorefractive crystal. A method of replaying an off-axis hologram includes: illuminating a photorefractive crystal having a holographic diffraction grating with a replay beam.

Three-dimensional stereotactic atlas of the extracranial vasculature correlated with the intracranial vasculature, cranial nerves, skull and muscles

PubMed Central

Shoon Let Thaung, Thant; Choon Chua, Beng; Hnin Wut Yi, Su; Yang, Yili; Urbanik, Andrzej

2015-01-01

Our objective was to construct a 3D, interactive, and reference atlas of the extracranial vasculature spatially correlated with the intracranial blood vessels, cranial nerves, skull, glands, and head muscles. The atlas has been constructed from multiple 3T and 7T magnetic resonance angiogram (MRA) brain scans, and 3T phase contrast and inflow MRA neck scans of the same specimen in the following steps: vessel extraction from the scans, building 3D tubular models of the vessels, spatial registration of the extra- and intracranial vessels, vessel editing, vessel naming and color-coding, vessel simplification, and atlas validation. This new atlas contains 48 names of the extracranial vessels (25 arterial and 23 venous) and it has been integrated with the existing brain atlas. The atlas is valuable for medical students and residents to easily get familiarized with the extracranial vasculature with a few clicks; is useful for educators to prepare teaching materials; and potentially can serve as a reference in the diagnosis of vascular disease and treatment, including craniomaxillofacial surgeries and radiologic interventions of the face and neck. PMID:25923683

Distance-dependent processing of pictures and words.

PubMed

Amit, Elinor; Algom, Daniel; Trope, Yaacov

2009-08-01

A series of 8 experiments investigated the association between pictorial and verbal representations and the psychological distance of the referent objects from the observer. The results showed that people better process pictures that represent proximal objects and words that represent distal objects than pictures that represent distal objects and words that represent proximal objects. These results were obtained with various psychological distance dimensions (spatial, temporal, and social), different tasks (classification and categorization), and different measures (speed of processing and selective attention). The authors argue that differences in the processing of pictures and words emanate from the physical similarity of pictures, but not words, to the referents. Consequently, perceptual analysis is commonly applied to pictures but not to words. Pictures thus impart a sense of closeness to the referent objects and are preferably used to represent such objects, whereas words do not convey proximity and are preferably used to represent distal objects in space, time, and social perspective.

The implementation of aerial object recognition algorithm based on contour descriptor in FPGA-based on-board vision system

NASA Astrophysics Data System (ADS)

Babayan, Pavel; Smirnov, Sergey; Strotov, Valery

2017-10-01

This paper describes the aerial object recognition algorithm for on-board and stationary vision system. Suggested algorithm is intended to recognize the objects of a specific kind using the set of the reference objects defined by 3D models. The proposed algorithm based on the outer contour descriptor building. The algorithm consists of two stages: learning and recognition. Learning stage is devoted to the exploring of reference objects. Using 3D models we can build the database containing training images by rendering the 3D model from viewpoints evenly distributed on a sphere. Sphere points distribution is made by the geosphere principle. Gathered training image set is used for calculating descriptors, which will be used in the recognition stage of the algorithm. The recognition stage is focusing on estimating the similarity of the captured object and the reference objects by matching an observed image descriptor and the reference object descriptors. The experimental research was performed using a set of the models of the aircraft of the different types (airplanes, helicopters, UAVs). The proposed orientation estimation algorithm showed good accuracy in all case studies. The real-time performance of the algorithm in FPGA-based vision system was demonstrated.

Simple scheme to implement decoy-state reference-frame-independent quantum key distribution

NASA Astrophysics Data System (ADS)

Zhang, Chunmei; Zhu, Jianrong; Wang, Qin

2018-06-01

We propose a simple scheme to implement decoy-state reference-frame-independent quantum key distribution (RFI-QKD), where signal states are prepared in Z, X, and Y bases, decoy states are prepared in X and Y bases, and vacuum states are set to no bases. Different from the original decoy-state RFI-QKD scheme whose decoy states are prepared in Z, X and Y bases, in our scheme decoy states are only prepared in X and Y bases, which avoids the redundancy of decoy states in Z basis, saves the random number consumption, simplifies the encoding device of practical RFI-QKD systems, and makes the most of the finite pulses in a short time. Numerical simulations show that, considering the finite size effect with reasonable number of pulses in practical scenarios, our simple decoy-state RFI-QKD scheme exhibits at least comparable or even better performance than that of the original decoy-state RFI-QKD scheme. Especially, in terms of the resistance to the relative rotation of reference frames, our proposed scheme behaves much better than the original scheme, which has great potential to be adopted in current QKD systems.

Investigating Commercial Cellulase Performances Toward Specific Biomass Recalcitrance Factors Using Reference Substrates

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ju, Xiaohui; Bowden, Mark E.; Engelhard, Mark H.

Three commercial cellulase preparations, Novozymes Cellic® Ctec2, Dupont Accellerase® 1500, and DSM Cytolase CL, were evaluated for their hydrolytic activity using a set of reference biomass substrates with controlled substrate characteristics. It was found that lignin remains a significant recalcitrance factor to all the preparations, although different enzyme preparations respond to the inhibitory effect of lignin differently. Also, different types of biomass lignin can inhibit cellulose enzymes in different manners. Enhancing enzyme activity toward biomass fiber swelling is an area significantly contributing to potential improvement in cellulose performance. While the degree of polymerization of cellulose in the reference substrates didmore » not present a major recalcitrance factor to Novozymes Cellic® Ctec2, cellulose crystallite has been shown to have a significant lower reactivity toward all enzyme mixtures. The presence of polysaccharide monooxygenases (PMOs) in Novozymes Ctec2 appears to enhance enzyme activity toward decrystallization of cellulose. This study demonstrated that reference substrates with controlled chemical and physical characteristics of structural features can be applied as an effective and practical strategy to identify cellulosic enzyme activities toward specific biomass recalcitrance factor(s) and provide specific targets for enzyme improvement.« less

Investigating commercial cellulase performances toward specific biomass recalcitrance factors using reference substrates.

PubMed

Ju, Xiaohui; Bowden, Mark; Engelhard, Mark; Zhang, Xiao

2014-05-01

Three commercial cellulase preparations, Novozymes Cellic(®) Ctec2, Dupont Accellerase(®) 1500, and DSM Cytolase CL, were evaluated for their hydrolytic activity using a set of reference biomass substrates with controlled substrate characteristics. It was found that lignin remains a significant recalcitrance factor to all the preparations, although different enzyme preparations respond to the inhibitory effect of lignin differently. Also, different types of biomass lignin can inhibit cellulase enzymes in different manners. Enhancing enzyme activity toward biomass fiber swelling is an area significantly contributing to potential improvement in cellulase performance. While the degree of polymerization of cellulose in the reference substrates did not present a major recalcitrance factor to Novozymes Cellic(®) Ctec2, cellulose crystallite has been shown to have a significant lower reactivity toward all enzyme mixtures. The presence of polysaccharide monooxygenases (PMOs) in Novozymes Ctec2 appears to enhance enzyme activity toward decrystallization of cellulose. This study demonstrated that reference substrates with controlled chemical and physical characteristics of structural features can be applied as an effective and practical strategy to identify cellulosic enzyme activities toward specific biomass recalcitrance factor(s) and provide specific targets for enzyme improvement.

42 CFR 7.1 - Applicability.

Code of Federal Regulations, 2012 CFR

2012-10-01

... BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.1 Applicability. The provisions of this part are applicable to private entities requesting from the Centers for Disease Control (CDC) reference biological standards and biological preparations for use in their laboratories. ...

42 CFR 7.1 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-10-01

... BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.1 Applicability. The provisions of this part are applicable to private entities requesting from the Centers for Disease Control (CDC) reference biological standards and biological preparations for use in their laboratories. ...

42 CFR 7.1 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-10-01

... BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.1 Applicability. The provisions of this part are applicable to private entities requesting from the Centers for Disease Control (CDC) reference biological standards and biological preparations for use in their laboratories. ...

Prosodic Temporal Alignment of Co-Speech Gestures to Speech Facilitates Referent Resolution

ERIC Educational Resources Information Center

Jesse, Alexandra; Johnson, Elizabeth K.

2012-01-01

Using a referent detection paradigm, we examined whether listeners can determine the object speakers are referring to by using the temporal alignment between the motion speakers impose on objects and their labeling utterances. Stimuli were created by videotaping speakers labeling a novel creature. Without being explicitly instructed to do so,…

The Role of Competition in Word Learning via Referent Selection

ERIC Educational Resources Information Center

Horst, Jessica S.; Scott, Emilly J.; Pollard, Jessica A.

2010-01-01

Previous research suggests that competition among the objects present during referent selection influences young children's ability to learn words in fast mapping tasks. The present study systematically explored this issue with 30-month-old children. Children first received referent selection trials with a target object and either two, three or…

The International Standard for Oxytetracycline

PubMed Central

Humphrey, J. H.; Lightbown, J. W.; Mussett, M. V.; Perry, W. L. M.

1955-01-01

The first attempt to set up an international standard for oxytetracycline, using oxytetracycline hydrochloride, failed because of difficulties in obtaining a preparation whose moisture content was uniform after distribution into ampoules. A preparation of dihydrate of oxytetracycline base was obtained instead, and was compared in an international collaborative assay with a sample of oxytetracycline hydrochloride, which was the current working standard of Chas. Pfizer & Co., Inc., USA. The results of the collaborative assay showed that the potency of the dihydrate was uniform, and that it was a suitable preparation for use as the International Standard. Evidence was obtained, however, that the reference preparation at the time of examination was less potent than had been originally supposed, and that it was hydrated. The potency of the proposed international standard was recalculated after allowance for water in the reference preparation, and the resulting biological potency agreed well with that to be expected on the basis of the physicochemical properties of the preparation. It was agreed, therefore, that the recalculated values should be used, and the preparation of oxytetracycline base dihydrate used in the collaborative assay is established as the International Standard for Oxytetracycline with a potency of 900 International Units per mg. PMID:13284563

Content-based fused off-axis object illumination direct-to-digital holography

DOEpatents

Price, Jeffery R.

2006-05-02

Systems and methods are described for content-based fused off-axis illumination direct-to-digital holography. A method includes calculating an illumination angle with respect to an optical axis defined by a focusing lens as a function of data representing a Fourier analyzed spatially heterodyne hologram; reflecting a reference beam from a reference mirror at a non-normal angle; reflecting an object beam from an object the object beam incident upon the object at the illumination angle; focusing the reference beam and the object beam at a focal plane of a digital recorder to from the content-based off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; and digitally recording the content based off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis.

Gravimetric preparation and characterization of primary reference solutions of molybdenum and rhodium.

PubMed

Kaltenbach, Angela; Noordmann, Janine; Görlitz, Volker; Pape, Carola; Richter, Silke; Kipphardt, Heinrich; Kopp, Gernot; Jährling, Reinhard; Rienitz, Olaf; Güttler, Bernd

2015-04-01

Gravimetrically prepared mono-elemental reference solutions having a well-known mass fraction of approximately 1 g/kg (or a mass concentration of 1 g/L) define the very basis of virtually all measurements in inorganic analysis. Serving as the starting materials of all standard/calibration solutions, they link virtually all measurements of inorganic analytes (regardless of the method applied) to the purity of the solid materials (high-purity metals or salts) they were prepared from. In case these solid materials are characterized comprehensively with respect to their purity, this link also establishes direct metrological traceability to The International System of Units (SI). This, in turn, ensures the comparability of all results on the highest level achievable. Several national metrology institutes (NMIs) and designated institutes (DIs) have been working for nearly two decades in close cooperation with commercial producers on making an increasing number of traceable reference solutions available. Besides the comprehensive characterization of the solid starting materials, dissolving them both loss-free and completely under strict gravimetric control is a challenging problem in the case of several elements like molybdenum and rhodium. Within the framework of the European Metrology Research Programme (EMRP), in the Joint Research Project (JRP) called SIB09 Primary standards for challenging elements, reference solutions of molybdenum and rhodium were prepared directly from the respective metals with a relative expanded uncertainty associated with the mass fraction of U rel(w) < 0.05 %. To achieve this, a microwave-assisted digestion procedure for Rh and a hotplate digestion procedure for Mo were developed along with highly accurate and precise inductively coupled plasma optical emission spectrometry (ICP OES) and multicollector inductively coupled plasma mass spectrometry (MC-ICP-MS) methods required to assist with the preparation and as dissemination tools.

Measurement of Dam Deformations: Case Study of Obruk Dam (Turkey)

NASA Astrophysics Data System (ADS)

Gulal, V. Engin; Alkan, R. Metin; Alkan, M. Nurullah; İlci, Veli; Ozulu, I. Murat; Tombus, F. Engin; Kose, Zafer; Aladogan, Kayhan; Sahin, Murat; Yavasoglu, Hakan; Oku, Guldane

2016-04-01

In the literature, there is information regarding the first deformation and displacement measurements in dams that were conducted in 1920s Switzerland. Todays, deformation measurements in the dams have gained very different functions with improvements in both measurement equipment and evaluation of measurements. Deformation measurements and analysis are among the main topics studied by scientists who take interest in the engineering measurement sciences. The Working group of Deformation Measurements and Analysis, which was established under the International Federation of Surveyors (FIG), carries out its studies and activities with regard to this subject. At the end of the 1970s, the subject of the determination of fixed points in the deformation monitoring network was one of the main subjects extensively studied. Many theories arose from this inquiry, as different institutes came to differing conclusions. In 1978, a special commission with representatives of universities has been established within the FIG 6.1 working group; this commission worked on the issue of determining a general approach to geometric deformation analysis. The results gleaned from the commission were discussed at symposiums organized by the FIG. In accordance with these studies, scientists interested in the subject have begun to work on models that investigate cause and effect relations between the effects that cause deformation and deformation. As of the scientist who interest with the issue focused on different deformation methods, another special commission was established within the FIG engineering measurements commission in order to classify deformation models and study terminology. After studying this material for a long time, the official commission report was published in 2001. In this prepared report, studies have been carried out by considering the FIG Engineering Surveying Commission's report entitled, 'MODELS AND TERMINOLOGY FOR THE ANALYSIS OF GEODETIC MONITORING OBSERVATIONS'. In October of 2015, geodetic deformation measurements were conducted by considering FIG reports related to deformation measurements and German DIN 18710 Engineering Measurements norms in the Çorum province of Turkey. The main purpose of the study is to determine optimum measurement and evaluation methods that will be used to specify movements in the horizontal and vertical directions for the fill dam. For this purpose; • In reference networks consisting of 8 points, measurements were performed by using long-term dual-frequency GNSS receivers for duration of 8 hours. • GNSS measurements were conducted in varying times between 30 minutes and 120 minutes at the 44 units object points on the body of the dam. • Two repetitive measurements of real time kinematic (RTK) GNSS were conducted at the object points on dam. • Geometric leveling measurements were performed between reference and object points. • Trigonometric leveling measurements were performed between reference and object points. • Polar measurements were performed between references and object points. GNSS measurements performed at reference points of the monitoring network for 8 hours have been evaluated by using GAMIT software in accordance with the IGS points in the region. In this manner, regional and local movements in the network can be determined. It is aimed to determine measurement period which will provide 1-2mm accuracy that expected in local GNSS network by evaluating GNSS measurements performed on body of dam. Results will be compared by offsetting GNSS and terrestrial measurements. This study will investigate whether or not there is increased accuracy provided by GNSS measurements carried out among reference points without the possibility of vision.

Evaluation of preparation methods for suspended nano-objects on substrates for dimensional measurements by atomic force microscopy

PubMed Central

Göhler, Daniel; Wessely, Benno; Stintz, Michael; Lazzerini, Giovanni Mattia; Yacoot, Andrew

2017-01-01

Dimensional measurements on nano-objects by atomic force microscopy (AFM) require samples of safely fixed and well individualized particles with a suitable surface-specific particle number on flat and clean substrates. Several known and proven particle preparation methods, i.e., membrane filtration, drying, rinsing, dip coating as well as electrostatic and thermal precipitation, were performed by means of scanning electron microscopy to examine their suitability for preparing samples for dimensional AFM measurements. Different suspensions of nano-objects (with varying material, size and shape) stabilized in aqueous solutions were prepared therefore on different flat substrates. The drop-drying method was found to be the most suitable one for the analysed suspensions, because it does not require expensive dedicated equipment and led to a uniform local distribution of individualized nano-objects. Traceable AFM measurements based on Si and SiO2 coated substrates confirmed the suitability of this technique. PMID:28904839

Evaluation of preparation methods for suspended nano-objects on substrates for dimensional measurements by atomic force microscopy.

PubMed

Fiala, Petra; Göhler, Daniel; Wessely, Benno; Stintz, Michael; Lazzerini, Giovanni Mattia; Yacoot, Andrew

2017-01-01

Dimensional measurements on nano-objects by atomic force microscopy (AFM) require samples of safely fixed and well individualized particles with a suitable surface-specific particle number on flat and clean substrates. Several known and proven particle preparation methods, i.e., membrane filtration, drying, rinsing, dip coating as well as electrostatic and thermal precipitation, were performed by means of scanning electron microscopy to examine their suitability for preparing samples for dimensional AFM measurements. Different suspensions of nano-objects (with varying material, size and shape) stabilized in aqueous solutions were prepared therefore on different flat substrates. The drop-drying method was found to be the most suitable one for the analysed suspensions, because it does not require expensive dedicated equipment and led to a uniform local distribution of individualized nano-objects. Traceable AFM measurements based on Si and SiO 2 coated substrates confirmed the suitability of this technique.

Linking language to the visual world: Neural correlates of comprehending verbal reference to objects through pointing and visual cues.

PubMed

Peeters, David; Snijders, Tineke M; Hagoort, Peter; Özyürek, Aslı

2017-01-27

In everyday communication speakers often refer in speech and/or gesture to objects in their immediate environment, thereby shifting their addressee's attention to an intended referent. The neurobiological infrastructure involved in the comprehension of such basic multimodal communicative acts remains unclear. In an event-related fMRI study, we presented participants with pictures of a speaker and two objects while they concurrently listened to her speech. In each picture, one of the objects was singled out, either through the speaker's index-finger pointing gesture or through a visual cue that made the object perceptually more salient in the absence of gesture. A mismatch (compared to a match) between speech and the object singled out by the speaker's pointing gesture led to enhanced activation in left IFG and bilateral pMTG, showing the importance of these areas in conceptual matching between speech and referent. Moreover, a match (compared to a mismatch) between speech and the object made salient through a visual cue led to enhanced activation in the mentalizing system, arguably reflecting an attempt to converge on a jointly attended referent in the absence of pointing. These findings shed new light on the neurobiological underpinnings of the core communicative process of comprehending a speaker's multimodal referential act and stress the power of pointing as an important natural device to link speech to objects. Copyright © 2016 Elsevier Ltd. All rights reserved.

Report of the panel on earth rotation and reference frames, section 7

NASA Technical Reports Server (NTRS)

Dickey, Jean O.; Dickman, Steven R.; Eubanks, Marshall T.; Feissel, Martine; Herring, Thomas A.; Mueller, Ivan I.; Rosen, Richard D.; Schutz, Robert E.; Wahr, John M.; Wilson, Charles R.

1991-01-01

Objectives and requirements for Earth rotation and reference frame studies in the 1990s are discussed. The objectives are to observe and understand interactions of air and water with the rotational dynamics of the Earth, the effects of the Earth's crust and mantle on the dynamics and excitation of Earth rotation variations over time scales of hours to centuries, and the effects of the Earth's core on the rotational dynamics and the excitation of Earth rotation variations over time scales of a year or longer. Another objective is to establish, refine and maintain terrestrial and celestrial reference frames. Requirements include improvements in observations and analysis, improvements in celestial and terrestrial reference frames and reference frame connections, and improved observations of crustal motion and mass redistribution on the Earth.

A word processor optimized for preparing journal articles and student papers.

PubMed

Wolach, A H; McHale, M A

2001-11-01

A new Windows-based word processor for preparing journal articles and student papers is described. In addition to standard features found in word processors, the present word processor provides specific help in preparing manuscripts. Clicking on "Reference Help (APA Form)" in the "File" menu provides a detailed help system for entering the references in a journal article. Clicking on "Examples and Explanations of APA Form" provides a help system with examples of the various sections of a review article, journal article that has one experiment, or journal article that has two or more experiments. The word processor can automatically place the manuscript page header and page number at the top of each page using the form required by APA and Psychonomic Society journals. The "APA Form" submenu of the "Help" menu provides detailed information about how the word processor is optimized for preparing articles and papers.

Method and apparatus for assessing material properties of sheet-like materials

DOEpatents

Telschow, Kenneth L.; Deason, Vance A.

2002-01-01

Apparatus for producing an indication of a material property of a sheet-like material according to the present invention may comprise an excitation source for vibrating the sheet-like material to produce at least one traveling wave therein. A light source configured to produce an object wavefront and a reference wavefront directs the object wavefront toward the sheet-like material to produce a modulated object wavefront. A modulator operatively associated with the reference wavefront modulates the reference wavefront in synchronization with the traveling wave on the sheet-like material to produce a modulated reference wavefront. A sensing medium positioned to receive the modulated object wavefront and the modulated reference wavefront produces an image of the traveling wave in the sheet-like material, the image of the anti-symmetric traveling wave being related to a displacement amplitude of the anti-symmetric traveling wave over a two-dimensional area of the vibrating sheet-like material. A detector detects the image of the traveling wave in the sheet-like material.

A novel assay for detecting antibodies to cytochrome P4502D6, the molecular target of liver kidney microsomal antibody type 1.

PubMed

Kerkar, N; Ma, Y; Hussain, M; Muratori, L; Targett, C; Williams, R; Bianchi, F B; Mieli-Vergani, G; Vergani, D

1999-03-04

Liver Kidney Microsomal type 1 (LKM1) antibody, the diagnostic marker of autoimmune hepatitis type 2, is also found in a proportion of patients with hepatitis C virus infection (HCV). It is detected conventionally by the subjective immunofluorescence technique. Our aim was to establish a simple and objective enzyme-linked immunosorbent assay (ELISA) that measures antibodies to cytochrome P4502D6 (CYP2D6), the target of LKM1. An indirect ELISA using eukaryotically expressed CYP2D6 was designed. Absorbance values obtained against a reference microsomal preparation were subtracted from those obtained against a microsomal preparation over-expressing CYP2D6, thus removing the non-CYP2D6-specific reaction. Sera from 51 LKM1 positive patients (21 autoimmune hepatitis and 30 with HCV infection), 111 LKM1 negative patients with chronic liver disease (including 20 with HCV infection) and 43 healthy controls were tested. Of 51 patients positive by immunofluorescence, 48 were also positive by ELISA while all the 154 LKM1 negative subjects were also negative by ELISA. There was a high degree of association between IFL and ELISA as demonstrated by a kappa reliability value of 0.96. The absorbance values by ELISA correlated with immunofluorescence LKM1 titres both in autoimmune hepatitis (r = 0.74, p < 0.001) and HCV infection (r = 0.67, p < 0.001). The simple, objective ELISA described has the potential to replace the standard immunofluorescence technique.

Spatially-Heterodyned Holography

DOEpatents

Thomas, Clarence E [Knoxville, TN; Hanson, Gregory R [Clinton, TN

2006-02-21

A method of recording a spatially low-frequency heterodyne hologram, including spatially heterodyne fringes for Fourier analysis, includes: splitting a laser beam into a reference beam and an object beam; interacting the object beam with an object; focusing the reference beam and the object beam at a focal plane of a digital recorder to form a spatially low-frequency heterodyne hologram including spatially heterodyne fringes for Fourier analysis; digital recording the spatially low-frequency heterodyne hologram; Fourier transforming axes of the recorded spatially low-frequency heterodyne hologram including spatially heterodyne fringes in Fourier space to sit on top of a heterodyne carrier frequency defined by an angle between the reference beam and the object beam; cutting off signals around an origin; and performing an inverse Fourier transform.

Noise-free recovery of optodigital encrypted and multiplexed images.

PubMed

Henao, Rodrigo; Rueda, Edgar; Barrera, John F; Torroba, Roberto

2010-02-01

We present a method that allows storing multiple encrypted data using digital holography and a joint transform correlator architecture with a controllable angle reference wave. In this method, the information is multiplexed by using a key and a different reference wave angle for each object. In the recovering process, the use of different reference wave angles prevents noise produced by the nonrecovered objects from being superimposed on the recovered object; moreover, the position of the recovered object in the exit plane can be fully controlled. We present the theoretical analysis and the experimental results that show the potential and applicability of the method.

Continued Development and Improvement of Pneumatic Heavy Vehicles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert J. Englar

2005-07-15

The objective of this applied research effort led by Georgia Tech Research Institute is the application of pneumatic aerodynamic technology previously developed and patented by us to the design of an appropriate Heavy Vehicle (HV) tractor-trailer configuration, and experimental confirmation of this pneumatic configuration's improved aerodynamic characteristics. In Phases I to IV of our previous DOE program (Reference 1), GTRI has developed, patented, wind-tunnel tested and road-tested blown aerodynamic devices for Pneumatic Heavy Vehicles (PHVs) and Pneumatic Sports Utility Vehicles (PSUVs). To further advance these pneumatic technologies towards HV and SUV applications, additional Phase V tasks were included in themore » first year of a continuing DOE program (Reference 2). Based on the results of the Phase IV full-scale test programs, these Phase V tasks extended the application of pneumatic aerodynamics to include: further economy and performance improvements; increased aerodynamic stability and control; and safety of operation of Pneumatic HVs. Continued development of a Pneumatic SUV was also conducted during the Phase V program. Phase V was completed in July, 2003; its positive results towards development and confirmation of this pneumatic technology are reported in References 3 and 4. The current Phase VI of this program was incrementally funded by DOE in order to continue this technology development towards a second fuel economy test on the Pneumatic Heavy Vehicle. The objectives of this current Phase VI research and development effort (Ref. 5) fall into two categories: (1) develop improved pneumatic aerodynamic technology and configurations on smaller-scale models of the advanced Pneumatic Heavy Vehicle (PHV); and based on these findings, (2) redesign, modify, and re-test the modified full-scale PHV test vehicle. This second objective includes conduct of an on-road preliminary road test of this configuration to prepare it for a second series of SAE Type-U fuel economy evaluations, as described in Ref. 5. Both objectives are based on the pneumatic technology already developed and confirmed for DOE OHVT/OAAT in Phases I-V. This new Phase VI effort was initiated by contract amendment to the Phase V effort using carryover FY02 funds. This were conducted under a new and distinct project number, GTRI Project A-6935, separate from the Phase I-IV program. However, the two programs are closely integrated, and thus Phase VI continues with the previous program and goals.« less

Development of Lentivirus-Based Reference Materials for Ebola Virus Nucleic Acid Amplification Technology-Based Assays.

PubMed

Mattiuzzo, Giada; Ashall, James; Doris, Kathryn S; MacLellan-Gibson, Kirsty; Nicolson, Carolyn; Wilkinson, Dianna E; Harvey, Ruth; Almond, Neil; Anderson, Robert; Efstathiou, Stacey; Minor, Philip D; Page, Mark

2015-01-01

The 2013-present Ebola virus outbreak in Western Africa has prompted the production of many diagnostic assays, mostly based on nucleic acid amplification technologies (NAT). The calibration and performance assessment of established assays and those under evaluation requires reference materials that can be used in parallel with the clinical sample to standardise or control for every step of the procedure, from extraction to the final qualitative/quantitative result. We have developed safe and stable Ebola virus RNA reference materials by encapsidating anti sense viral RNA into HIV-1-like particles. The lentiviral particles are replication-deficient and non-infectious due to the lack of HIV-1 genes and Envelope protein. Ebola virus genes were subcloned for encapsidation into two lentiviral preparations, one containing NP-VP35-GP and the other VP40 and L RNA. Each reference material was formulated as a high-titre standard for use as a calibrator for secondary or internal standards, and a 10,000-fold lower titre preparation to serve as an in-run control. The preparations have been freeze-dried to maximise stability. These HIV-Ebola virus RNA reference materials were suitable for use with in-house and commercial quantitative RT-PCR assays and with digital RT-PCR. The HIV-Ebola virus RNA reference materials are stable at up to 37°C for two weeks, allowing the shipment of the material worldwide at ambient temperature. These results support further evaluation of the HIV-Ebola virus RNA reference materials as part of an International collaborative study for the establishment of the 1st International Standard for Ebola virus RNA.

An object memory bias induced by communicative reference.

PubMed

Marno, Hanna; Davelaar, Eddy J; Csibra, Gergely

2016-01-01

In humans, a good proportion of knowledge, including knowledge about objects and object kinds, is acquired via social learning by direct communication from others. If communicative signals raise the expectation of social learning about objects, intrinsic (permanent) features that support object recognition are relevant to store into memory, while extrinsic (accidental) object properties can be ignored. We investigated this hypothesis by instructing participants to memorise shape-colour associations that constituted either an extrinsic object property (the colour of the box that contained the object, Experiment 1) or an intrinsic one (the colour of the object, Experiment 2). Compared to a non-communicative context, communicative presentation of the objects impaired participants' performance when they recalled extrinsic object properties, while their incidental memory of the intrinsic shape-colour associations was not affected. Communicative signals had no effect on performance when the task required the memorisation of intrinsic object properties. The negative effect of communicative reference on the memory of extrinsic properties was also confirmed in Experiment 3, where this property was object location. Such a memory bias suggests that referent objects in communication tend to be seen as representatives of their kind rather than as individuals. Copyright © 2015 Elsevier B.V. All rights reserved.

Recording multiple spatially-heterodyned direct to digital holograms in one digital image

DOEpatents

Hanson, Gregory R [Clinton, TN; Bingham, Philip R [Knoxville, TN

2008-03-25

Systems and methods are described for recording multiple spatially-heterodyned direct to digital holograms in one digital image. A method includes digitally recording, at a first reference beam-object beam angle, a first spatially-heterodyned hologram including spatial heterodyne fringes for Fourier analysis; Fourier analyzing the recorded first spatially-heterodyned hologram by shifting a first original origin of the recorded first spatially-heterodyned hologram to sit on top of a first spatial-heterodyne carrier frequency defined by the first reference beam-object beam angle; digitally recording, at a second reference beam-object beam angle, a second spatially-heterodyned hologram including spatial heterodyne fringes for Fourier analysis; Fourier analyzing the recorded second spatially-heterodyned hologram by shifting a second original origin of the recorded second spatially-heterodyned hologram to sit on top of a second spatial-heterodyne carrier frequency defined by the second reference beam-object beam angle; applying a first digital filter to cut off signals around the first original origin and define a first result; performing a first inverse Fourier transform on the first result; applying a second digital filter to cut off signals around the second original origin and define a second result; and performing a second inverse Fourier transform on the second result, wherein the first reference beam-object beam angle is not equal to the second reference beam-object beam angle and a single digital image includes both the first spatially-heterodyned hologram and the second spatially-heterodyned hologram.

32 CFR Appendix A to Part 1290 - Preparation Guide for DD Form 1805, Violation Notice

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Preparation Guide for DD Form 1805, Violation Notice A Appendix A to Part 1290 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS PREPARING AND PROCESSING MINOR OFFENSES AND VIOLATION NOTICES REFERRED TO U.S...

Engineering Drawing Practices - Volume I of II: Aerospace and Ground Support Equipment

NASA Technical Reports Server (NTRS)

Schwindt, Paul A.

2015-01-01

This manual establishes the essential requirements and reference documents for the preparation and revision of digital product definition data sets prepared for or by NASA at KSC. This volume is only applicable to KSC in-house programs/projects. These requirements do not apply to the preparation of illustrations, artwork, or figures in technical publications.

32 CFR Appendix A to Part 1290 - Preparation Guide for DD Form 1805, Violation Notice

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Preparation Guide for DD Form 1805, Violation Notice A Appendix A to Part 1290 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS PREPARING AND PROCESSING MINOR OFFENSES AND VIOLATION NOTICES REFERRED TO U.S...

32 CFR Appendix A to Part 1290 - Preparation Guide for DD Form 1805, Violation Notice

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Preparation Guide for DD Form 1805, Violation Notice A Appendix A to Part 1290 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS PREPARING AND PROCESSING MINOR OFFENSES AND VIOLATION NOTICES REFERRED TO U.S...

32 CFR Appendix A to Part 1290 - Preparation Guide for DD Form 1805, Violation Notice

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Preparation Guide for DD Form 1805, Violation Notice A Appendix A to Part 1290 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS PREPARING AND PROCESSING MINOR OFFENSES AND VIOLATION NOTICES REFERRED TO U.S...

USE OF NATURAL WATERS AS U. S. GEOLOGICAL SURVEY REFERENCE SAMPLES.

USGS Publications Warehouse

Janzer, Victor J.

1985-01-01

The U. S. Geological Survey conducts research and collects hydrologic data relating to the Nation's water resources. Seven types of natural matrix reference water samples are prepared for use in the Survey's quality assurance program. These include samples containing major constituents, trace metals, nutrients, herbicides, insecticides, trace metals in a water and suspended-sediment mixture, and precipitation (snowmelt). To prepare these reference samples, natural water is collected in plastic drums and the sediment is allowed to settle. The water is then filtered, selected constituents are added, and if necessary the water is acidified and sterilized by ultraviolet irradiation before bottling in plastic or glass. These reference samples are distributed twice yearly to more than 100 laboratories for chemical analysis. The most probable values for each constituent are determined by evaluating the data submitted by the laboratories using statistical techniques recommended by ASTM.

Object Orientation Affects Spatial Language Comprehension

ERIC Educational Resources Information Center

Burigo, Michele; Sacchi, Simona

2013-01-01

Typical spatial descriptions, such as "The car is in front of the house," describe the position of a located object (LO; e.g., the car) in space relative to a reference object (RO) whose location is known (e.g., the house). The orientation of the RO affects spatial language comprehension via the reference frame selection process.…

ALT-114 and ALT-118 Alternative Approaches to NIST ...

EPA Pesticide Factsheets

In 2016, US EPA approved two separate alternatives (ALT 114 and ALT 118) for the preparation and certification of Hydrogen Chloride (HCl) and Mercury (Hg) cylinder reference gas standards that can serve as EPA Protocol gases where EPA Protocol are required, but unavailable. The alternatives were necessary due to the unavailability of NIST reference materials (SRM, NTRM, CRM or RGM) or VSL reference materials (VSL PRM or VSL CRM), reference materials identified in EPA’s Green Book as necessary to establish the traceability of EPA protocol gases. ALT 114 and ALT 118 provides a pathway for gas vendors to prepare and certify traceable gas cylinder standards for use in certifying Hg and HCl CEMS. In this presentation, EPA will describe the mechanics and requirements of the performance-based approach, provide an update on the availability of these gas standards and also discuss the potential for producing and certifying gas standards for other compounds using this approach. This presentation discusses the importance of NIST-traceable reference gases relative to regulatory source compliance emissions monitoring. Specifically this presentation discusses 2 new approaches for making necessary reference gases available in the absence of NIST reference materials. Moreover, these approaches provide an alternative approach to rapidly make available new reference gases for additional HAPS regulatory compliance emissions measurement and monitoring.

Identification and Illustration of Insecure Direct Object References and their Countermeasures

NASA Astrophysics Data System (ADS)

KumarShrestha, Ajay; Singh Maharjan, Pradip; Paudel, Santosh

2015-03-01

The insecure direct object reference simply represents the flaws in the system design without the full protection mechanism for the sensitive system resources or data. It basically occurs when the web application developer provides direct access to objects in accordance with the user input. So any attacker can exploit this web vulnerability and gain access to privileged information by bypassing the authorization. The main aim of this paper is to demonstrate the real effect and the identification of the insecure direct object references and then to provide the feasible preventive solutions such that the web applications do not allow direct object references to be manipulated by attackers. The experiment of the insecure direct object referencing is carried out using the insecure J2EE web application called WebGoat and its security testing is being performed using another JAVA based tool called BURP SUITE. The experimental result shows that the access control check for gaining access to privileged information is a very simple problem but at the same time its correct implementation is a tricky task. The paper finally presents some ways to overcome this web vulnerability.

Top-down preparation modulates visual categorization but not subjective awareness of objects presented in natural backgrounds.

PubMed

Koivisto, Mika; Kahila, Ella

2017-04-01

Top-down processes are widely assumed to be essential in visual awareness, subjective experience of seeing. However, previous studies have not tried to separate directly the roles of different types of top-down influences in visual awareness. We studied the effects of top-down preparation and object substitution masking (OSM) on visual awareness during categorization of objects presented in natural scene backgrounds. The results showed that preparation facilitated categorization but did not influence visual awareness. OSM reduced visual awareness and impaired categorization. The dissociations between the effects of preparation and OSM on visual awareness and on categorization imply that they influence at different stages of cognitive processing. We propose that preparation influences at the top of the visual hierarchy, whereas OSM interferes with processes occurring at lower levels of the hierarchy. These lower level processes play an essential role in visual awareness. Copyright © 2017 Elsevier Ltd. All rights reserved.

Advanced Curation Activities at NASA: Preparing to Receive, Process, and Distribute Samples Returned from Future Missions

NASA Technical Reports Server (NTRS)

McCubbin, Francis M.; Zeigler, Ryan A.

2017-01-01

The Astromaterials Acquisition and Curation Office (henceforth referred to herein as NASA Curation Office) at NASA Johnson Space Center (JSC) is responsible for curating all of NASA's extraterrestrial samples. Under the governing document, NASA Policy Directive (NPD) 7100.10F JSC is charged with curation of all extraterrestrial material under NASA control, including future NASA missions. The Directive goes on to define Curation as including documentation, preservation, preparation, and distribution of samples for research, education, and public outreach. Here we briefly describe NASA's astromaterials collections and our ongoing efforts related to enhancing the utility of our current collections as well as our efforts to prepare for future sample return missions. We collectively refer to these efforts as advanced curation.

Case report: a work simulation program for a manual worker with a fracture injury.

PubMed

Chan, Chi-Chung; Chow, Jonathan H.W.

2000-01-01

Work rehabilitation programs targeting different client groups are available in nearly all major hospital occupational therapy departments in Hong Kong. Clients receiving work rehabilitation are referred from various out-patient clinics and other occupational therapists. Those clients experience limitation in work after their injuries or diseases and plan to return to work after rehabilitation. Program objectives are 1) to assist clients to reach maximum work capacity as rapidly as possible 2) to ensure clients return to work safely 3) to improve clients' work readiness. This case report describes an individualized work simulation program at a general hospital in Hong Kong provided for a typical client who is preparing to return to his worker role. Specific job analysis, goals and program rationale for the client are discussed.

Survey material choices in haematology EQA: a confounding factor in automated counting performance assessment.

PubMed

De la Salle, Barbara

2017-02-15

The complete blood count (CBC) is one of the most frequently requested tests in laboratory medicine, performed in a range of healthcare situations. The provision of an ideal assay material for external quality assessment is confounded by the fragility of the cellular components of blood, the lack of commutability of stabilised whole blood material and the lack of certified reference materials and methods to which CBC results can be traced. The choice of assay material between fresh blood, extended life assay material and fully stabilised, commercially prepared, whole blood material depends upon the scope and objectives of the EQA scheme. The introduction of new technologies in blood counting and the wider clinical application of parameters from the extended CBC will bring additional challenges for the EQA provider.

Actuating materials. Voxelated liquid crystal elastomers.

PubMed

Ware, Taylor H; McConney, Michael E; Wie, Jeong Jae; Tondiglia, Vincent P; White, Timothy J

2015-02-27

Dynamic control of shape can bring multifunctionality to devices. Soft materials capable of programmable shape change require localized control of the magnitude and directionality of a mechanical response. We report the preparation of soft, ordered materials referred to as liquid crystal elastomers. The direction of molecular order, known as the director, is written within local volume elements (voxels) as small as 0.0005 cubic millimeters. Locally, the director controls the inherent mechanical response (55% strain) within the material. In monoliths with spatially patterned director, thermal or chemical stimuli transform flat sheets into three-dimensional objects through controlled bending and stretching. The programmable mechanical response of these materials could yield monolithic multifunctional devices or serve as reconfigurable substrates for flexible devices in aerospace, medicine, or consumer goods. Copyright © 2015, American Association for the Advancement of Science.

Scientific and educational recommender systems

NASA Astrophysics Data System (ADS)

Guseva, A. I.; Kireev, V. S.; Bochkarev, P. V.; Kuznetsov, I. A.; Philippov, S. A.

2017-01-01

This article discusses the questions associated with the use of reference systems in the preparation of graduates in physical function. The objective of this research is creation of model of recommender system user from the sphere of science and education. The detailed review of current scientific and social network for scientists and the problem of constructing recommender systems in this area. The result of this study is to research user information model systems. The model is presented in two versions: the full one - in the form of a semantic network, and short - in a relational form. The relational model is the projection in the form of semantic network, taking into account the restrictions on the amount of bonds that characterize the number of information items (research results), which interact with the system user.

Children’s level of word knowledge predicts their exclusion of familiar objects as referents of novel words

PubMed Central

Grassmann, Susanne; Schulze, Cornelia; Tomasello, Michael

2015-01-01

When children are learning a novel object label, they tend to exclude as possible referents familiar objects for which they already have a name. In the current study, we wanted to know if children would behave in this same way regardless of how well they knew the name of potential referent objects, specifically, whether they could only comprehend it or they could both comprehend and produce it. Sixty-six monolingual German-speaking 2-, 3-, and 4-year-old children participated in two experimental sessions. In one session the familiar objects were chosen such that their labels were in the children’s productive vocabularies, and in the other session the familiar objects were chosen such that their labels were only in the children’s receptive vocabularies. Results indicated that children at all three ages were more likely to exclude a familiar object as the potential referent of the novel word if they could comprehend and produce its name rather than comprehend its name only. Indeed, level of word knowledge as operationalized in this way was a better predictor than was age. These results are discussed in the context of current theories of word learning by exclusion. PMID:26322005

Measurement of susceptibility artifacts with histogram-based reference value on magnetic resonance images according to standard ASTM F2119.

PubMed

Heinrich, Andreas; Teichgräber, Ulf K; Güttler, Felix V

2015-12-01

The standard ASTM F2119 describes a test method for measuring the size of a susceptibility artifact based on the example of a passive implant. A pixel in an image is considered to be a part of an image artifact if the intensity is changed by at least 30% in the presence of a test object, compared to a reference image in which the test object is absent (reference value). The aim of this paper is to simplify and accelerate the test method using a histogram-based reference value. Four test objects were scanned parallel and perpendicular to the main magnetic field, and the largest susceptibility artifacts were measured using two methods of reference value determination (reference image-based and histogram-based reference value). The results between both methods were compared using the Mann-Whitney U-test. The difference between both reference values was 42.35 ± 23.66. The difference of artifact size was 0.64 ± 0.69 mm. The artifact sizes of both methods did not show significant differences; the p-value of the Mann-Whitney U-test was between 0.710 and 0.521. A standard-conform method for a rapid, objective, and reproducible evaluation of susceptibility artifacts could be implemented. The result of the histogram-based method does not significantly differ from the ASTM-conform method.

Services for Older Adults. Reference Book [and] Student Activity Book.

ERIC Educational Resources Information Center

Texas Tech Univ., Lubbock. Curriculum Center for Family and Consumer Sciences.

This student activity book and reference book, which are part of a family and consumer sciences education series focusing on a broad range of employment opportunities, are intended for use in 1- and 2- programs preparing Texas high school students for employment in occupations related to providing services for older adults. The reference book…

Guidance Provided to Authors on Citing and Formatting References in Nursing Journals

PubMed Central

Nicoll, Leslie H.; Oermann, Marilyn H.; Chinn, Peggy L.; Conklin, Jamie L.; Amarasekara, Sathya; McCarty, Midori

2018-01-01

Reference citations should be accurate, complete, and presented in a consistent format. This study analyzed information provided to authors on preparing citations and references for manuscripts submitted to nursing journals (n = 209). Half of the journals used the American Psychological Association reference style. Slightly more than half provided examples of how to cite articles and books; there were fewer examples of citing websites and online journals. Suggestions on improving accuracy of references are discussed. PMID:29346137

Antigenic value of lyophilized phenolized antirabies vaccine.

PubMed

VEERARAGHAVAN, N; SUBRAHMANYAN, T P

1961-01-01

The authors present the results of experiments, carried out at the Pasteur Institute of Southern India, Coonoor, in which various preparations of lyophilized and liquid phenolized antirabies vaccines were assessed for antigenicity in relation to the NIH (United States National Institutes of Health) Reference Vaccine 164 (the proposed International Reference Preparation of Rabies Vaccine). The claim that phenolized antirabies vaccines can be lyophilized without loss of antigenicity was fully substantiated: the lyophilized vaccines were found to possess high antigenic values and to retain their antigenicity better than the liquid vaccines during storage under the same conditions.

Standard method of test for grindability of coal by the Hardgrove-machine method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1975-01-01

A procedure is described for sampling coal, grinding in a Hardgrove grinding machine, and passing through standard sieves to determine the degree of pulverization of coals. The grindability index of the coal tested is calculated from a calibration chart prepared by plotting weight of material passing a No. 200 sieve versus the Hardgrove Grindability Index for the standard reference samples. The Hardgrove machine is shown schematically. The method for preparing and determining grindability indexes of standard reference samples is given in the appendix. (BLM)

Software System User’s Manual, Reference Manual, and Installation Guide for the Test Engineer’s Assistant System.

DTIC Science & Technology

1989-02-28

AD-A259 245 RESEARCH TRIANGLE INSTITUTE I SOFTWARE SYSTEM USER’S MANUAL, REFERENCE MANUAL, AND INSTALLATION GUIDE FOR THE TEST ENGINEER’S ASSISTANT...SYSTEM U. yD"VxC - February 28, 1989 Iŕ 5 G3 ’Contract No. DAAL01-86-C-0039 W Prepared for: Department of the Army Electronics Research and...Development Command Fort Monmouth, New Jersey 07703 I Prepared by: Center for Digital Systems ResearchI Research Triangle Institute Research Triangle Park, NC

X-ray Moiré deflectometry using synthetic reference images

DOE PAGES

Stutman, Dan; Valdivia, Maria Pia; Finkenthal, Michael

2015-06-25

Moiré fringe deflectometry with grating interferometers is a technique that enables refraction-based x-ray imaging using a single exposure of an object. To obtain the refraction image, the method requires a reference fringe pattern (without the object). Our study shows that, in order to avoid artifacts, the reference pattern must be exactly matched in phase with the object fringe pattern. In experiments, however, it is difficult to produce a perfectly matched reference pattern due to unavoidable interferometer drifts. We present a simple method to obtain matched reference patterns using a phase-scan procedure to generate synthetic Moiré images. As a result, themore » method will enable deflectometric diagnostics of transient phenomena such as laser-produced plasmas and could improve the sensitivity and accuracy of medical phase-contrast imaging.« less

Spot auto-focusing and spot auto-stigmation methods with high-definition auto-correlation function in high-resolution TEM.

PubMed

Isakozawa, Shigeto; Fuse, Taishi; Amano, Junpei; Baba, Norio

2018-04-01

As alternatives to the diffractogram-based method in high-resolution transmission electron microscopy, a spot auto-focusing (AF) method and a spot auto-stigmation (AS) method are presented with a unique high-definition auto-correlation function (HD-ACF). The HD-ACF clearly resolves the ACF central peak region in small amorphous-thin-film images, reflecting the phase contrast transfer function. At a 300-k magnification for a 120-kV transmission electron microscope, the smallest areas used are 64 × 64 pixels (~3 nm2) for the AF and 256 × 256 pixels for the AS. A useful advantage of these methods is that the AF function has an allowable accuracy even for a low s/n (~1.0) image. A reference database on the defocus dependency of the HD-ACF by the pre-acquisition of through-focus amorphous-thin-film images must be prepared to use these methods. This can be very beneficial because the specimens are not limited to approximations of weak phase objects but can be extended to objects outside such approximations.

[Preparation and certification of mussel reference material for organochlorine pesticides and polychlorinated biphenyls using isotope dilution-high resolution mass spectrometry].

PubMed

Lu, Xianbo; Chen, Jiping; Wang, Shuqiu; Zou, Lili; Tian, Yuzeng; Ni, Yuwen; Su, Fan

2012-09-01

A method for the preparation and certification of the reference material of organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) in mussel tissue is described. The mussel tissue from Dalian Bay was frozen-dried, comminuted, sieved, homogenized, packaged, and sterilized by 60Co radiation sterilization in turn. The certified values for 18 OCPs and 16 PCBs were determined by high resolution gas chromatography/high resolution mass spectrometry (HRGC/HRMS) using isotope dilution and internal standard quantitation techniques. The certified values were validated and given based on seven accredited laboratories, and these values are traceable to the SI (international system of units) through gravimetrically prepared standards of established purity and measurement intercomparisons. The certified values of PCBs and OCPs in mussel span 4 orders of magnitude with a relative uncertainty of about 10%. This material is a natural biological material with confirmed good homogeneity and stability, and it was approved as the grade "primary reference material" (GBW10069) in June 2012 in China. This reference material provided necessary quality control products for our country to implement the Stockholm Treaty on the monitoring of persistent organic pollutants (POPs). The material is intended to be used for the method validation and quality control in the determination of OCPs and PCBs in biota samples.

Shifting attention in viewer- and object-based reference frames after unilateral brain injury.

PubMed

List, Alexandra; Landau, Ayelet N; Brooks, Joseph L; Flevaris, Anastasia V; Fortenbaugh, Francesca C; Esterman, Michael; Van Vleet, Thomas M; Albrecht, Alice R; Alvarez, Bryan D; Robertson, Lynn C; Schendel, Krista

2011-06-01

The aims of the present study were to investigate the respective roles that object- and viewer-based reference frames play in reorienting visual attention, and to assess their influence after unilateral brain injury. To do so, we studied 16 right hemisphere injured (RHI) and 13 left hemisphere injured (LHI) patients. We used a cueing design that manipulates the location of cues and targets relative to a display comprised of two rectangles (i.e., objects). Unlike previous studies with patients, we presented all cues at midline rather than in the left or right visual fields. Thus, in the critical conditions in which targets were presented laterally, reorienting of attention was always from a midline cue. Performance was measured for lateralized target detection as a function of viewer-based (contra- and ipsilesional sides) and object-based (requiring reorienting within or between objects) reference frames. As expected, contralesional detection was slower than ipsilesional detection for the patients. More importantly, objects influenced target detection differently in the contralesional and ipsilesional fields. Contralesionally, reorienting to a target within the cued object took longer than reorienting to a target in the same location but in the uncued object. This finding is consistent with object-based neglect. Ipsilesionally, the means were in the opposite direction. Furthermore, no significant difference was found in object-based influences between the patient groups (RHI vs. LHI). These findings are discussed in the context of reference frames used in reorienting attention for target detection. Published by Elsevier Ltd.

Program for creating an operating system generation cross reference index (SGINDEX)

NASA Technical Reports Server (NTRS)

Barth, C. W.

1972-01-01

Computer program to collect key data from Stage Two input of OS/360 system and to prepare formatted listing of index entries collected is discussed. Program eliminates manual paging through system output by providing comprehensive cross reference.

[A model list of high risk drugs].

PubMed

Cotrina Luque, J; Guerrero Aznar, M D; Alvarez del Vayo Benito, C; Jimenez Mesa, E; Guzman Laura, K P; Fernández Fernández, L

2013-12-01

«High-risk drugs» are those that have a very high «risk» of causing death or serious injury if an error occurs during its use. The Institute for Safe Medication Practices (ISMP) has prepared a high-risk drugs list applicable to the general population (with no differences between the pediatric and adult population). Thus, there is a lack of information for the pediatric population. The main objective of this work is to develop a high-risk drug list adapted to the neonatal or pediatric population as a reference model for the pediatric hospital health workforce. We made a literature search in May 2012 to identify any published lists or references in relation to pediatric and/or neonatal high-risk drugs. A total of 15 studies were found, from which 9 were selected. A model list was developed mainly based on the ISMP one, adding strongly perceived pediatric risk drugs and removing those where the pediatric use was anecdotal. There is no published list that suits pediatric risk management. The list of pediatric and neonatal high-risk drugs presented here could be a «reference list of high-risk drugs » for pediatric hospitals. Using this list and training will help to prevent medication errors in each drug supply chain (prescribing, transcribing, dispensing and administration). Copyright © 2013 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

Qualitative computer aided evaluation of dental impressions in vivo.

PubMed

Luthardt, Ralph G; Koch, Rainer; Rudolph, Heike; Walter, Michael H

2006-01-01

Clinical investigations dealing with the precision of different impression techniques are rare. Objective of the present study was to develop and evaluate a procedure for the qualitative analysis of the three-dimensional impression precision based on an established in-vitro procedure. The zero hypothesis to be tested was that the precision of impressions does not differ depending on the impression technique used (single-step, monophase and two-step-techniques) and on clinical variables. Digital surface data of patient's teeth prepared for crowns were gathered from standardized manufactured master casts after impressions with three different techniques were taken in a randomized order. Data-sets were analyzed for each patient in comparison with the one-step impression chosen as the reference. The qualitative analysis was limited to data-points within the 99.5%-range. Based on the color-coded representation areas with maximum deviations were determined (preparation margin and the mantle and occlusal surface). To qualitatively analyze the precision of the impression techniques, the hypothesis was tested in linear models for repeated measures factors (p < 0.05). For the positive 99.5% deviations no variables with significant influence were determined in the statistical analysis. In contrast, the impression technique and the position of the preparation margin significantly influenced the negative 99.5% deviations. The influence of clinical parameter on the deviations between impression techniques can be determined reliably using the 99.5 percentile of the deviations. An analysis regarding the areas with maximum deviations showed high clinical relevance. The preparation margin was pointed out as the weak spot of impression taking.

Development and Application of the Remote Food Photography Method to Measure Food Intake in Exclusively Milk Fed Infants: A Laboratory-Based Study

PubMed Central

Altazan, Abby D.; Gilmore, L. Anne; Burton, Jeffrey H.; Ragusa, Shelly A.; Apolzan, John W.; Martin, Corby K.; Redman, Leanne M.

2016-01-01

Background Accurate methods of assessing food intake in infants are needed to assess the relationship between infant feeding practices and risk of childhood obesity. Current methods are either subjective or have limited ability for use beyond clinical research settings. Objective To assess the accuracy of the RFPM to evaluate simulated milk intake including energy, macronutrient, and micronutrient intake compared to direct weighing within a controlled study. Methods Individuals were recruited to prepare three 2 fl oz, 4 fl oz, 6 fl oz, and 8 fl oz servings of infant formula and to capture photographs at different stages of preparation (dry powdered formula, prepared formula, and liquid waste) using the SmartIntake® application. Gram weights of the bottles were obtained by the RFPM and direct weighing. Using the United States Department of Agriculture National Nutrient Database for Standard Reference, energy, macronutrient, and micronutrient values were generated from gram weights. Results Intake of formula prepared from powder measured by the RFPM was equivalent to weighed intake within 7.5% equivalence bounds among all servings and each serving size. The mean difference between methods varied among servings sizes with the RFPM underestimating intake by 1.6 ± 0.4 kcals in 2 fl oz servings, 4.8 ± 0.6 kcals in 4 fl oz servings, and 6.2 ± 1.0 kcals in 6 fl oz servings, and overestimating intake by 0.1 ± 1.2 kcals in 8 fl oz servings. Bland-Altman analysis showed that the RFPM overestimated intake at lower levels food intake and underestimated intake at higher levels. Considering photographs of only the prepared formula bottle and the bottle with formula waste to simulate ready-to-feed formula and human breast milk, intake estimated by the RFPM was equivalent to the directly weighed intake within 7.5% for all servings. Conclusions The RFPM has higher accuracy than subjective methods and similar accuracy as compared to the objective methods in estimating simulated intake of milk and formula with lower burden to caregivers. The RFPM is a viable method for measuring intake in exclusively milk fed infants by caregivers in a controlled environment with potential for widespread use in research and clinical practice. PMID:27684949

Chat Reference Training after One Decade: The Results of a National Survey of Academic Libraries

ERIC Educational Resources Information Center

Devine, Christopher; Paladino, Emily Bounds; Davis, John A.

2011-01-01

The first comprehensive national survey of all academic libraries in the United States which were conducting chat reference service was carried out to determine: what practices were being used to prepare personnel for chat reference service, what competencies were being taught, how and why training practices may have changed over time, and what…

By any other name: when will preschoolers produce several labels for a referent?

PubMed

Deák, G O; Yen, L; Pettit, J

2001-10-01

Two experiments investigated why preschool children sometimes produce multiple words for a referent (i.e. polynomy), but other times seem to allow only one word. In Experiment 1, 40 three- and four-year-olds completed a modification of Deák & Maratsos' (1998) naming task. Although social demands to produce multiple words were reduced, children produced, on average, more than two words per object. Number of words produced was predicted by receptive vocabulary. Lexical insight (i.e. knowing that a word refers to function or appearance) and metalexical beliefs (i.e. that a hypothetical referent has one label, or more than one) were not preconditions of polynomy. Polynomy was independent of bias to map novel words to unfamiliar referents. In Experiment 2, 40 three- and four-year-olds learned new words for nameable objects. Children showed a correction effect, yet produced more than two words per object. Children do not have a generalized one-word-per-object bias, even during word learning. Other explanations (e.g. contextual restriction of lexical access) are discussed.

An Interlingual-based Approach to Reference Resolution

DTIC Science & Technology

2000-01-01

unclassified c . THIS PAGE unclassified Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 They do not generally consider implicit references or...AMOUNT: C [currency] etc. where TIME, LOCATION, AGENT, THEME, human, organization, object, etc. are all ontological concepts. On some particular...AMOUNT: C [currency] etc. These instantiated representational objects are, in turn, referents in the discourse context when the next sentence is

Spectral multivariate calibration without laboratory prepared or determined reference analyte values.

PubMed

Ottaway, Josh; Farrell, Jeremy A; Kalivas, John H

2013-02-05

An essential part to calibration is establishing the analyte calibration reference samples. These samples must characterize the sample matrix and measurement conditions (chemical, physical, instrumental, and environmental) of any sample to be predicted. Calibration usually requires measuring spectra for numerous reference samples in addition to determining the corresponding analyte reference values. Both tasks are typically time-consuming and costly. This paper reports on a method named pure component Tikhonov regularization (PCTR) that does not require laboratory prepared or determined reference values. Instead, an analyte pure component spectrum is used in conjunction with nonanalyte spectra for calibration. Nonanalyte spectra can be from different sources including pure component interference samples, blanks, and constant analyte samples. The approach is also applicable to calibration maintenance when the analyte pure component spectrum is measured in one set of conditions and nonanalyte spectra are measured in new conditions. The PCTR method balances the trade-offs between calibration model shrinkage and the degree of orthogonality to the nonanalyte content (model direction) in order to obtain accurate predictions. Using visible and near-infrared (NIR) spectral data sets, the PCTR results are comparable to those obtained using ridge regression (RR) with reference calibration sets. The flexibility of PCTR also allows including reference samples if such samples are available.

42 CFR 7.4 - Schedule of charges.

Code of Federal Regulations, 2012 CFR

2012-10-01

... REFERENCE BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.4 Schedule of charges. The charges imposed in... ingredients. Charges may vary over time and between different biological standards or biological preparations... is available from the Biological Products Branch, Center for Infectious Diseases, Centers for Disease...

42 CFR 7.1 - Applicability.

Code of Federal Regulations, 2014 CFR

2014-10-01

... BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.1 Applicability. The provisions of this part are applicable to private entities requesting from the Centers for Disease Control and Prevention (CDC) reference biological Standards and Biological preparations for use in their laboratories. [78 FR 43820, July 22, 2013] ...

42 CFR 7.1 - Applicability.

Code of Federal Regulations, 2013 CFR

2013-10-01

... BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.1 Applicability. The provisions of this part are applicable to private entities requesting from the Centers for Disease Control and Prevention (CDC) reference biological Standards and Biological preparations for use in their laboratories. [78 FR 43820, July 22, 2013] ...

42 CFR 7.4 - Schedule of charges.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REFERENCE BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.4 Schedule of charges. The charges imposed in... ingredients. Charges may vary over time and between different biological standards or biological preparations... is available from the Biological Products Branch, Center for Infectious Diseases, Centers for Disease...

The Scholars We Need: Preparing Transdisciplinary Professionals by Leveraging the Scholarship of Practice

ERIC Educational Resources Information Center

McDaniels, Melissa; Skogsberg, Erik

2017-01-01

In this chapter we call for immediate action to prepare more dynamic transdisciplinary professionals by leveraging the scholarship of practice. Transdisciplinary refers to contexts both inside and outside of the academy where today's doctoral students will work.

Adaptation of the Sensititre broth microdilution technique to antimicrobial susceptibility testing of Mycoplasma hyopneumoniae.

PubMed

Tanner, A C; Erickson, B Z; Ross, R F

1993-09-01

A broth microdilution technique is described for determining the antimicrobial susceptibility of Mycoplasma hyopneumoniae, using commercially prepared Sensititre plates. Twenty-five field isolates and two reference strains (J & 232), were tested against seven antimicrobials. Field isolates were tested in duplicate and reference strains, four times to estimate reproducibility. Ninety-seven percent of the duplicate MIC results for the field isolates were in agreement, or within one log2 dilution. Similar results were obtained with the reference strains. The isolates were susceptible to lincomycin-spectinomycin, tylosin and oxytetracycline or resistant to amoxycillin, apramycin and erythromycin. Susceptibility to furaltadone varied. This method retains the accuracy and reproducibility of broth MIC determinations, while avoiding the lengthy preparation of antimicrobial dilutions normally associated with more traditional methods.

Relative bioavailability of rifampicin, isoniazid and ethambutol from a combination tablet vs. concomitant administration of a capsule containing rifampicin and a tablet containing isoniazid and ethambutol.

PubMed

Schall, R; Müller, F O; Duursema, L; Groenewoud, G; Hundt, H K; Middle, M V; Mogilnicka, E M; Swart, K J

1995-11-01

Twenty male volunteers who were slow metabolisers of isoniazid, completed this single-blind, single-dose, randomised, cross-over study to compare the bioavailability of rifampicin (CAS 13292-46-1), isoniazid (CAS 54-85-3) and ethambutol (CAS 1070-11-7) from Myrin tablets (test preparation) with the bioavailability of these drugs from a combination of capsules containing rifampicin and tablets containing isoniazid and ethambutol (reference). There were 2 treatment periods and on clinic days volunteers were given either the reference (300 mig rifampicin plus 200 mg isoniazid and 600 mg ethambutol HCl), or the test preparation (300 mg rifampicin, 150 mg isoniazid and 600 mg ethambutol HCl). Serial blood samples were drawn from the volunteers and rifampicin, isoniazid and ethambutol assays were performed. The results of this study indicate that the test preparation is equivalent to the reference with respect to both the rate and the extent of absorption of rifampicin, isoniazid (after adjustment for the different doses of isoniazid and ethambutol).

Method for Statically Checking an Object-oriented Computer Program Module

NASA Technical Reports Server (NTRS)

Bierhoff, Kevin M. (Inventor); Aldrich, Jonathan (Inventor)

2012-01-01

A method for statically checking an object-oriented computer program module includes the step of identifying objects within a computer program module, at least one of the objects having a plurality of references thereto, possibly from multiple clients. A discipline of permissions is imposed on the objects identified within the computer program module. The permissions enable tracking, from among a discrete set of changeable states, a subset of states each object might be in. A determination is made regarding whether the imposed permissions are violated by a potential reference to any of the identified objects. The results of the determination are output to a user.

Objective and Subjective Intra-patient Comparison of Iohexol versus Diatrizoate for Bowel Preparation Quality at CT Colonography

PubMed Central

Johnson, Brandon; Hinshaw, J. Louis; Robbins, Jessica B.; Pickhardt, Perry J.

2017-01-01

Objective To objectively and subjectively compare nonionic iohexol and ionic diatrizoate iodinated oral contrast as part of a cathartic bowel regimen within the same CT colonography (CTC) cohort, with otherwise identical preparations. Materials and Methods In our IRB-approved retrospective study, 46 asymptomatic adults (mean age, 59.4 years; 26M/20F) returning for follow-up CTC over a 9-month interval underwent the same bowel preparation with the exception of 75 ml iohexol 350 (Omnipaque) in place of 60 ml diatrizoate (Gastrografin). All other preparation components (bisacodyl, magnesium citrate, and 2% barium) remained constant. Objective volumetric analysis of residual colonic fluid volume and fluid attenuation was performed. Additionally, two radiologists experienced with CTC, blinded to the specific bowel preparation, scored each of 6 colonic segments for adherent residual solid stool using a previously validated 4-point scale (0 for no stool; 1–3 for increasing residual stool). Paired t-test was used for comparison of the cohorts. Results No clear clinically-meaningful difference was found between the two preparations on overall objective or subjective evaluation. Mean (±SD) residual fluid volume was 173±126 ml with the iohexol preparation and 130±79 ml with the diatrizoate prep (p=0.02). Mean total colonic stool score was 2.5 (0.42/segment) with iohexol and 2.3 (0.38/segment) with diatrizoate (p=0.69). Mean (±SD) fluid attenuation was higher with iohexol (849±270HU) compared with diatrizoate (732±168HU) (p=0.03). Conclusions Based on this direct intra-patient comparison, we found that oral iohexol is a suitable alternative to diatrizoate for fluid tagging as part of a cathartic bowel preparation at CTC. Because this nonionic tagging agent is more palatable, less expensive, and likely safer than ionic diatrizoate, our CTC program now utilizes iohexol as the standard recommended regimen. PMID:27010251

A method of camera calibration in the measurement process with reference mark for approaching observation space target

NASA Astrophysics Data System (ADS)

Zhang, Hua; Zeng, Luan

2017-11-01

Binocular stereoscopic vision can be used for space-based space targets near observation. In order to solve the problem that the traditional binocular vision system cannot work normally after interference, an online calibration method of binocular stereo measuring camera with self-reference is proposed. The method uses an auxiliary optical imaging device to insert the image of the standard reference object into the edge of the main optical path and image with the target on the same focal plane, which is equivalent to a standard reference in the binocular imaging optical system; When the position of the system and the imaging device parameters are disturbed, the image of the standard reference will change accordingly in the imaging plane, and the position of the standard reference object does not change. The camera's external parameters can be re-calibrated by the visual relationship of the standard reference object. The experimental results show that the maximum mean square error of the same object can be reduced from the original 72.88mm to 1.65mm when the right camera is deflected by 0.4 degrees and the left camera is high and low with 0.2° rotation. This method can realize the online calibration of binocular stereoscopic vision measurement system, which can effectively improve the anti - jamming ability of the system.

Methodological considerations for implementation of lymphocyte subset analysis in a clinical reference laboratory.

PubMed

Muirhead, K A; Wallace, P K; Schmitt, T C; Frescatore, R L; Franco, J A; Horan, P K

1986-01-01

As the diagnostic utility of lymphocyte subset analysis has been recognized in the clinical research laboratory, a wide variety of reagents and cell preparation, staining and analysis methods have also been described. Methods that are perfectly suitable for analysis of smaller sample numbers in the biological or clinical research setting are not always appropriate and/or applicable in the setting of a high volume clinical reference laboratory. We describe here some of the specific considerations involved in choosing a method for flow cytometric analysis which minimizes sample preparation and data analysis time while maximizing sample stability, viability, and reproducibility. Monoclonal T- and B-cell reagents from three manufacturers were found to give equivalent results for a reference population of healthy individuals. This was true whether direct or indirect immunofluorescence staining was used and whether cells were prepared by Ficoll-Hypaque fractionation (FH) or by lysis of whole blood. When B cells were enumerated using a polyclonal anti-immunoglobulin reagent, less cytophilic immunoglobulin staining was present after lysis than after FH preparation. However, both preparation methods required additional incubation at 37 degrees C to obtain results concordant with monoclonal B-cell reagents. Standard reagents were chosen on the basis of maximum positive/negative separation and the availability of appropriate negative controls. The effects of collection medium and storage conditions on sample stability and reproducibility of subset analysis were also assessed. Specimens collected in heparin and stored at room temperature in buffered medium gave reproducible results for 3 days after specimen collection, using either FH or lysis as the preparation method. General strategies for instrument optimization, quality control, and biohazard containment are also discussed.

The FASES instrument development and experiment preparation for the ISS

NASA Astrophysics Data System (ADS)

Picker, Gerold; Gollinger, Klaus; Greger, Ralf; Dettmann, Jan; Winter, Josef; Dewandre, Thierry; Castiglione, Luigi; Vincent-Bonnieu, Sebastien; Liggieri, Libero; Clausse, Daniele; Antoni, Mickael

The FASES experiments target the investigation of the stability of emulsions. The main objec-tives are the study of the surfactant adsorption at the liquid / liquid interfaces, the interaction of the droplets as well as the behaviour of the liquid film between nearby drops. Particular focus is given to the dynamic droplet evolution during emulsion destabilisation. The results of the experiments shall support development of methods for the modelling of droplet size distri-butions, which are important to many industries using stable emulsions like food production, cosmetics and pharmaceutics or unstable emulsions as required for applications in waste water treatment or crude oil recovery. The development of the experimental instrumentation was initiated in 2002. The flight instru-ment hardware development was started in 2004 and finally the flight unit was completed in 2009. Currently the final flight preparation is proceeding targeting a launch to the International Space Station (ISS) with Progress 39P in September 2010. The experiment setup of the instrument is accommodated in a box type insert called Experiment Container (EC), which will be installed in the Fluid Science Laboratory part of the European Columbus module of the ISS. The EC is composed of two diagnostics instruments for the investigation of transparent and opaque liquid emulsion. The transparent emulsions will be subject to the experiment called "Investigations on drop/drop interactions in Transparent Emulsions" (ITEM). The opaque emulsion samples will be studied in the experiment called "Investigations on concentrated or opaque Emulsions and on Phase Inversions" (EMPI). The thermal conditioning unit (TCU) allows performing homogeneous thermalization, tem-perature sweeps, emulsion preparation by stirrer, and optical diagnostics with a scanning mi-croscope. The objective of the instrument is the 3D reconstruction of the emulsion droplet distribution in the liquid matrix in terms of the droplet sizes, location and their time depen-dent evolution. The TCU will be used for the stability experiment ITEM-S and the droplet freezing experiment ITEM-F. The Differential Scanning Calorimeter (DSC) will give an information about the evolution of the emulsion through the droplet size distribution and the dispersion state of the droplets within the emulsion during a controlled temperature sweep by measuring the latent heat of droplet freezing and melting during the EMPI experiments. For this purpose the calorimeter is equipped with a reference sample filled with a pure liquid matrix and a similar measurement sample filled with the specific emulsion under investigation. The differential heat flux between measurement sample and reference sample is measured with a sensitive heat flux sensor. Each instrument is serviced by a robotic sample stowage system, which accommodates in total 44 different ITEM and EMPI emulsion samples each filled with a specific composition of the emulsion. Currently the flight preparation is ongoing with particular focus on the preparation of the emulsion flight sample set and the instrument's operating parameters. The FASES flight instrument was developed by ASTRIUM Space Transportation Germany with support of RUAG Aerospace Wallisellen under ESA / ESTEC contract. The science team of FASES is supported by ESA/ESTEC (Microgravity Application Programme, AO99-052).

National and international veterinary reference laboratories for infectious diseases.

PubMed

Edwards, S; Alexander, D

1998-08-01

Reference laboratories play an increasingly important role in the harmonisation of laboratory diagnostic tests and the standardisation of veterinary vaccines. This is particularly important in building confidence between international trading partners. The authors review aspects of the organisation, designation and support of reference laboratories for infectious diseases of animals and discuss the principal activities which such laboratories would normally perform. These activities include advice and consultancy, publications and communication, training, research, disease surveillance, maintenance of culture collections, evaluation of reference methods, preparation of reference materials and organisation of inter-laboratory comparisons.

[Environmental investigation of ground water contamination at Wright-Patterson Air Force Base, Ohio]. Volume 9, Removal action system design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-04-01

This Removal Action System Design has been prepared as a Phase I Volume for the implementation of the Phase II removal action at Wright-Patterson Air Force Base (WPAFB) near Dayton, Ohio. The objective of the removal action is to prevent, to the extent practicable, the migration of ground water contaminated with chlorinated volatile organic compounds (VOCS) across the southwest boundary of Area C. The Phase 1, Volume 9 Removal Action System Design compiles the design documents prepared for the Phase II Removal Action. These documents, which are presented in Appendices to Volume 9, include: Process Design, which presents the 30more » percent design for the ground water treatment system (GWTS); Design Packages 1 and 2 for Earthwork and Road Construction, and the Discharge Pipeline, respectively; no drawings are included in the appendix; Design Package 3 for installation of the Ground Water Extraction Well(s); Design Package 4 for installation of the Monitoring Well Instrumentation; and Design Package 5 for installation of the Ground Water Treatment System; this Design Package is incorporated by reference because of its size.« less

Fiber concentrate from orange (Citrus sinensis L.) bagase: characterization and application as bakery product ingredient.

PubMed

Romero-Lopez, Maria R; Osorio-Diaz, Perla; Bello-Perez, Luis A; Tovar, Juscelino; Bernardino-Nicanor, Aurea

2011-01-01

Orange is a tropical fruit used in the juice industry, yielding important quantities of by products. The objective of this work was to obtain a dietary fiber-rich orange bagasse product (DFROBP), evaluate its chemical composition and its use in the preparation of a bakery product (muffin). Muffins containing two different levels of DFROBP were studied regarding chemical composition, in vitro starch digestibility, predicted glyceamic index and acceptability in a sensory test. DFROBP showed low fat and high dietary fiber contents. The soluble and insoluble dietary fiber fractions were balanced, which is of importance for the health beneficial effects of fiber sources. DFROBP-containing muffins showed the same rapidly digestible starch content as the reference muffin, whilst the slowly digestible starch level increased with the addition of DFROBP. However, the resistant starch content decreased when DFROBP increased in the muffin. The addition of DFROBP to muffin decreased the predicted glyceamic index, but no difference was found between the muffins prepared with the two DFROBP levels. The sensory score did not show difference between control muffin and that added with 10% of DFROBP. The addition of DFROBP to bakery products can be an alternative for people requiring low glyceamic response.

New quality-control materials for the determination of alkylphenols and alkylphenol ethoxylates in sewage sludge.

PubMed

Fernández-Sanjuan, María; Lacorte, Silvia; Rigol, Anna; Sahuquillo, Angels

2012-11-01

The determination of alkylphenols in sewage sludge is still hindered by the complexity of the matrix and of the analytes, some of which are a mixture of isomers. Most of the methods published in the literature have not been validated, due to the lack of reference materials for the determination of alkylphenols in sludge. Given this situation, the objectives of the present study were to develop a new quality-control material for determining octylphenol, nonylphenol and nonylphenol monoethoxylate in sludge. The material was prepared from an anaerobically digested sewage sludge, which was thermally dried, sieved, homogenized and bottled after checking for the bulk homogeneity of the processed material. Together with the sewage sludge, an extract was also prepared, in order to provide a quality-control material for allowing laboratories to test the measuring step. The homogeneity and 1-year stability of the two materials were evaluated. Statistical analysis proved that the materials were homogeneous and stable for at least 1 year stored at different temperatures. These materials are intended to assist in the quality control of the determination of alkylphenols and alkylphenol ethoxylates in sewage sludge.

78 FR 62319 - Golden Pass Products, LLC, Golden Pass Pipeline, LLC; Notice of Intent To Prepare an...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-16

..., refer to the last page of this notice. Comments may be submitted in written form or verbally. Further... (DOE), Office of Fossil Energy, has agreed to participate as a cooperating agency in the preparation of...

Manufacture and quality control of interconnecting wire harnesses

NASA Technical Reports Server (NTRS)

1973-01-01

Four-volume series of documents has been prepared as standard reference. Each volume may be used separately and covers wire and cable preparation as well as harness fabrication and installation. Series should be useful addition to libraries of manufactures of electrical and electronic equipment.

Use of synthetic, crystalline, L-α-dimyristoyl lecithin in cardiolipin antigens

PubMed Central

Reyn, Alice; Bentzon, Michael Weis

1956-01-01

Experiments were carried out by the authors to determine whether synthetic, crystalline, L-α-dimyristoyl lecithin could replace natural purified lecithins in the preparation of cardiolipin antigens. These experiments were designed specifically to find out whether it was possible to obtain the same serological reactions, qualitatively and quantitatively, with the test antigen as with a reference antigen containing natural lecithin, and whether the test antigen had the same keeping qualities as the reference antigen. The tests used were the quantitative complement-fixation test as modified by Mørch in 1933, and the VDRL slide flocculation test. The results showed that synthetic, crystalline, L-α-dimyristoyl lecithin could replace natural lecithin in the preparation of cardiolipin antigens, but that the antigens prepared with the synthetic lecithin were significantly less sensitive than those prepared with an equimolar amount of natural lecithin. The authors consider that further investigation is required before the use of synthetic lecithin is finally adopted. PMID:13342931

Grasp Preparation Improves Change Detection for Congruent Objects

ERIC Educational Resources Information Center

Symes, Ed; Tucker, Mike; Ellis, Rob; Vainio, Lari; Ottoboni, Giovanni

2008-01-01

A series of experiments provided converging support for the hypothesis that action preparation biases selective attention to action-congruent object features. When visual transients are masked in so-called "change-blindness scenes," viewers are blind to substantial changes between 2 otherwise identical pictures that flick back and forth. The…

Data Sharing to Drive the Improvement of Teacher Preparation Programs

ERIC Educational Resources Information Center

Bastian, Kevin C.; Fortner, C. Kevin; Chapman, Alisa; Fleener, M. Jayne; McIntyre, Ellen; Patriarca, Linda A.

2016-01-01

Background/Context: Teacher preparation programs (TPPs) face increasing pressure from the federal government, states, and accreditation agencies to improve the quality of their practices and graduates, yet they often do not possess enough data to make evidence-based reforms. Purpose/Objective: This manuscript has four objectives: (a) to present…

Method for separating video camera motion from scene motion for constrained 3D displacement measurements

NASA Astrophysics Data System (ADS)

Gauthier, L. R.; Jansen, M. E.; Meyer, J. R.

2014-09-01

Camera motion is a potential problem when a video camera is used to perform dynamic displacement measurements. If the scene camera moves at the wrong time, the apparent motion of the object under study can easily be confused with the real motion of the object. In some cases, it is practically impossible to prevent camera motion, as for instance, when a camera is used outdoors in windy conditions. A method to address this challenge is described that provides an objective means to measure the displacement of an object of interest in the scene, even when the camera itself is moving in an unpredictable fashion at the same time. The main idea is to synchronously measure the motion of the camera and to use those data ex post facto to subtract out the apparent motion in the scene that is caused by the camera motion. The motion of the scene camera is measured by using a reference camera that is rigidly attached to the scene camera and oriented towards a stationary reference object. For instance, this reference object may be on the ground, which is known to be stationary. It is necessary to calibrate the reference camera by simultaneously measuring the scene images and the reference images at times when it is known that the scene object is stationary and the camera is moving. These data are used to map camera movement data to apparent scene movement data in pixel space and subsequently used to remove the camera movement from the scene measurements.

WHO Expert Committee on Specifications for Pharmaceutical Preparations.

PubMed

2009-01-01

The Expert Committee on Specifications for Pharmaceutical Preparations works towards clear, independent and practical standards and guidelines for the quality assurance of medicines. Standards are developed by the Committee through worldwide consultation and an international consensus-building process. The following new standards and guidelines were adopted and recommended for use: the current list of available International Chemical Reference Substances and International Infrared Reference Spectra; guidelines on stability testing of active pharmaceutical ingredients and finished pharmaceutical products; procedure for prequalification of pharmaceutical products; and the procedure for assessing the acceptability, in principle, of active pharmaceutical ingredients for use in pharmaceutical products.

Antigenic value of lyophilized phenolized antirabies vaccine

PubMed Central

Veeraraghavan, N.; Subrahmanyan, T. P.

1961-01-01

The authors present the results of experiments, carried out at the Pasteur Institute of Southern India, Coonoor, in which various preparations of lyophilized and liquid phenolized antirabies vaccines were assessed for antigenicity in relation to the NIH (United States National Institutes of Health) Reference Vaccine 164 (the proposed International Reference Preparation of Rabies Vaccine). The claim that phenolized antirabies vaccines can be lyophilized without loss of antigenicity was fully substantiated: the lyophilized vaccines were found to possess high antigenic values and to retain their antigenicity better than the liquid vaccines during storage under the same conditions. PMID:13925168

Reference Etiquette: A Guide to Excruciatingly Correct Behavior.

ERIC Educational Resources Information Center

Eckwright, Gail Z.; Pollastro, Mike; Hoskisson, Tam

1998-01-01

Presents suggestions for smooth and satisfying transactions between reference librarians and patrons, as well as for better collegial relationships. Highlights include: being prepared to help patrons; staying visible; serving "who's next"; working together and allowing for personal styles; making referrals; and using diplomacy while correcting…

Hollow-core photonic-crystal-fiber-based optical frequency references

NASA Astrophysics Data System (ADS)

Holá, Miroslava; Hrabina, Jan; Mikel, Břetislav; Lazar, Josef; Číp, Ondřej

2016-12-01

This research deals with preparation of an optical frequency references based on hollow-core photonic crystal fibers (HC-PCF). This fiber-based type of absorption cells represents a effiecient way how to replace classic bulky and fragile glass made tubes references with low-weight and low-volume optical fibers. This approach allows not only to increase possible interaction length between incident light and absorption media but it also carries a possibility of manufacturing of easy-operable reference which is set up just by plugging-in of optical connectors into the optical setup. We present the results of preparation, manufacturing and filling of a set of fiber-based cells intended for lasers frequency stabilization. The work deals with setting and optimalization of HC-PCF splicing processes, minimalization of optical losses between HC-PCF and SMF fiber transitions and finishing of HC-PCF spliced ends with special care for optimal closing of hollow-core structure needed for avoiding of absorption media leakage.

Optimized SIFTFlow for registration of whole-mount histology to reference optical images

PubMed Central

Shojaii, Rushin; Martel, Anne L.

2016-01-01

Abstract. The registration of two-dimensional histology images to reference images from other modalities is an important preprocessing step in the reconstruction of three-dimensional histology volumes. This is a challenging problem because of the differences in the appearances of histology images and other modalities, and the presence of large nonrigid deformations which occur during slide preparation. This paper shows the feasibility of using densely sampled scale-invariant feature transform (SIFT) features and a SIFTFlow deformable registration algorithm for coregistering whole-mount histology images with blockface optical images. We present a method for jointly optimizing the regularization parameters used by the SIFTFlow objective function and use it to determine the most appropriate values for the registration of breast lumpectomy specimens. We demonstrate that tuning the regularization parameters results in significant improvements in accuracy and we also show that SIFTFlow outperforms a previously described edge-based registration method. The accuracy of the histology images to blockface images registration using the optimized SIFTFlow method was assessed using an independent test set of images from five different lumpectomy specimens and the mean registration error was 0.32±0.22  mm. PMID:27774494

Astrometric Improvements for the USNO-A Catalog

NASA Astrophysics Data System (ADS)

Monet, D.

1997-12-01

The USNO-A1.0 catalog (Monet et al. 1996; 10 CD-ROMs; USNO) contains astrometric and photometric information for 488,006,860 objects. Since its compilation, many areas for improvement have been identified. This paper presents a progress report on the implementation of these improvements and discusses the schedule for the compilation of USNO-A2.0. The most significant improvement will be the incorporation of the International Celestial Reference Frame through the adoption of the ACT Catalog (Urban et al. in preparation; CD-ROM; USNO). (The ACT uses data from the Astrographic Catalog to compute proper motions for stars found in the Hipparcos and Tycho catalogs.) In addition to providing the realization of the astrometric reference frame, the ACT catalog contains a high enough source density to allow for a GSC-free derivation of the systematic components of the astrometric distortions found in the Schmidt telescopes that took the survey plates, and for a determination of the magnitude terms for the Palomar Schmidt using the data from the scans of the UJ plates. Other topics include the development of a numerical refocusing technique to improve the quality of existing scans, and the lessons being learned from the scanning of the Lick Northern Proper Motion survey plates.

Three-dimensional stereotactic atlas of the extracranial vasculature correlated with the intracranial vasculature, cranial nerves, skull and muscles.

PubMed

Nowinski, Wieslaw L; Shoon Let Thaung, Thant; Choon Chua, Beng; Hnin Wut Yi, Su; Yang, Yili; Urbanik, Andrzej

2015-04-01

Our objective was to construct a 3D, interactive, and reference atlas of the extracranial vasculature spatially correlated with the intracranial blood vessels, cranial nerves, skull, glands, and head muscles.The atlas has been constructed from multiple 3T and 7T magnetic resonance angiogram (MRA) brain scans, and 3T phase contrast and inflow MRA neck scans of the same specimen in the following steps: vessel extraction from the scans, building 3D tubular models of the vessels, spatial registration of the extra- and intracranial vessels, vessel editing, vessel naming and color-coding, vessel simplification, and atlas validation.This new atlas contains 48 names of the extracranial vessels (25 arterial and 23 venous) and it has been integrated with the existing brain atlas.The atlas is valuable for medical students and residents to easily get familiarized with the extracranial vasculature with a few clicks; is useful for educators to prepare teaching materials; and potentially can serve as a reference in the diagnosis of vascular disease and treatment, including craniomaxillofacial surgeries and radiologic interventions of the face and neck. © The Author(s) 2015 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

The species accuracy of the Most Probable Number (MPN) European Union reference method for enumeration of Escherichia coli in marine bivalves.

PubMed

Grevskott, Didrik Hjertaker; Svanevik, Cecilie Smith; Wester, Astrid Louise; Lunestad, Bjørn Tore

2016-12-01

Continuous European Union programmes with specified methods for enumeration of Escherichia coli in bivalves for human consumption are currently running. The objective of this research was to examine the species accuracy of the five times three tube Most Probable Number (MPN) EU reference method used for detection of E. coli in marine bivalves. Among 549 samples of bivalves harvested from Norwegian localities during 2014 and 2015, a total number of 200 bacterial isolates were prepared from randomly selected culture-positive bivalves. These presumptive E. coli isolates were characterized biochemically by the Analytical Profile Index (API) 20E, as well as by Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS). The majority of isolates (90%) were identified as E. coli, by both API 20E and MALDI-TOF MS. Ten isolates (5%) were identified as Klebsiella pneumoniae, while one isolate was identified as K. oxytoca by both methods, whereas three isolates were identified as Acinetobacter baumannii, Citrobacter braakii, and Enterobacter cloacae, respectively. The identification of the remaining six isolates were not in compliance between the two methods. Copyright © 2016 Elsevier B.V. All rights reserved.

National Athletic Trainers' Association Position Statement: Anabolic-Androgenic Steroids

PubMed Central

Kersey, Robert D.; Elliot, Diane L.; Goldberg, Linn; Kanayama, Gen; Leone, James E.; Pavlovich, Mike; Pope, Harrison G.

2012-01-01

This NATA position statement was developed by the NATA Research & Education Foundation. Objective This manuscript summarizes the best available scholarly evidence related to anabolic-androgenic steroids (AAS) as a reference for health care professionals, including athletic trainers, educators, and interested others. Background Health care professionals associated with sports or exercise should understand and be prepared to educate others about AAS. These synthetic, testosterone-based derivatives are widely abused by athletes and nonathletes to gain athletic performance advantages, develop their physiques, and improve their body image. Although AAS can be ergogenic, their abuse may lead to numerous negative health effects. Recommendations Abusers of AAS often rely on questionable information sources. Sports medicine professionals can therefore serve an important role by providing accurate, reliable information. The recommendations provide health care professionals with a current and accurate synopsis of the AAS-related research. PMID:23068595

Quantifying Human Response: Linking metrological and psychometric characterisations of Man as a Measurement Instrument

NASA Astrophysics Data System (ADS)

Pendrill, L. R.; Fisher, William P., Jr.

2013-09-01

A better understanding of how to characterise human response is essential to improved person-centred care and other situations where human factors are crucial. Challenges to introducing classical metrological concepts such as measurement uncertainty and traceability when characterising Man as a Measurement Instrument include the failure of many statistical tools when applied to ordinal measurement scales and a lack of metrological references in, for instance, healthcare. The present work attempts to link metrological and psychometric (Rasch) characterisation of Man as a Measurement Instrument in a study of elementary tasks, such as counting dots, where one knows independently the expected value because the measurement object (collection of dots) is prepared in advance. The analysis is compared and contrasted with recent approaches to this problem by others, for instance using signal error fidelity.

Electrochemistry in ethanol. I. Reference electrodes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zara, A.J.; de S. Bulhoes, L.O.

1982-01-01

The silver/silver nitrate electrode was found to be a suitable reference electrode in ethanolic solutions (2% v/v in water). The concentration of Ag/sup +/ inside the reference electrode is satisfactory in teh 0.1 to 10 mM concentration range. The liquid junction potential is minimized with sufficient supporting electrolyte (e.g., 0.1 to 0.5 M sodium perchlorate). The electrode is suitable for use as reference electrode in potentiometry and in polarography. Preparation is uncomplicated and the product is stable. 4 figures.

Meeting the Pepsi Challenge: Preparing Evaluation Programs for Scholastic Improvement.

ERIC Educational Resources Information Center

Hopkins, Mona S.

This document provides guidelines for preparing evaluation programs for scholastic improvement. The philosophy underlying assessment and accountability is discussed, with specific reference to the positive and negative aspects of assessment. The design of a curriculum evaluation model is presented, including goal identification, data gathering,…

Object-based connectedness facilitates matching.

PubMed

Koning, Arno; van Lier, Rob

2003-10-01

In two matching tasks, participants had to match two images of object pairs. Image-based (IB) connectedness refers to connectedness between the objects in an image. Object-based (OB) connectedness refers to connectedness between the interpreted objects. In Experiment 1, a monocular depth cue (shadow) was used to distinguish different relation types between object pairs. Three relation types were created: IB/OB-connected objects, IB/OB-disconnected objects, and IB-connected/OB-disconnected objects. It was found that IB/OB-connected objects were matched faster than IB/OB-disconnected objects. Objects that were IB-connected/OB-disconnected were matched equally to IB/OB-disconnected objects. In Experiment 2, stereoscopic presentation was used. With relation types comparable to those in Experiment 1, it was again found that OB connectedness determined speed of matching, rather than IB connectedness. We conclude that matching of projections of three-dimensional objects depends more on OB connectedness than on IB connectedness.

Radiometer calibration procedure and beacon attenuation estimation reference level

NASA Technical Reports Server (NTRS)

Crane, Robert K.

1994-01-01

The primary objectives are to compare radiometer attenuation with beacon attenuation and to compare sky temperature estimates with calculations using simultaneous meteorological data. Secondary objectives are: (1) noise diode and reference load measurements and (2) to adjust for outside temperature and component temperature changes.

Statistical Reference Datasets

National Institute of Standards and Technology Data Gateway

Statistical Reference Datasets (Web, free access)   The Statistical Reference Datasets is also supported by the Standard Reference Data Program. The purpose of this project is to improve the accuracy of statistical software by providing reference datasets with certified computational results that enable the objective evaluation of statistical software.

Evaluation of the Dark-Medium Objective Lens in Counting Asbestos Fibers by Phase-Contrast Microscopy

PubMed Central

Lee, Eun Gyung; Nelson, John H.; Kashon, Michael L.; Harper, Martin

2015-01-01

A Japanese round-robin study revealed that analysts who used a dark-medium (DM) objective lens reported higher fiber counts from American Industrial Hygiene Association (AIHA) Proficiency Analytical Testing (PAT) chrysotile samples than those using a standard objective lens, but the cause of this difference was not investigated at that time. The purpose of this study is to determine any major source of this difference by performing two sets of round-robin studies. For the first round-robin study, 15 AIHA PAT samples (five each of chrysotile and amosite generated by water-suspended method, and five chrysotile generated by aerosolization method) were prepared with relocatable cover slips and examined by nine laboratories. A second round-robin study was then performed with six chrysotile field sample slides by six out of nine laboratories who participated in the first round-robin study. In addition, two phase-shift test slides to check analysts’ visibility and an eight-form diatom test plate to compare resolution between the two objectives were examined. For the AIHA PAT chrysotile reference slides, use of the DM objective resulted in consistently higher fiber counts (1.45 times for all data) than the standard objective (P-value < 0.05), regardless of the filter generation (water-suspension or aerosol) method. For the AIHA PAT amosite reference and chrysotile field sample slides, the fiber counts between the two objectives were not significantly different. No statistically significant differences were observed in the visibility of blocks of the test slides between the two objectives. Also, the DM and standard objectives showed no pattern of differences in viewing the fine lines and/or dots of each species images on the eight-form diatom test plate. Among various potential factors that might affect the analysts’ performance of fiber counts, this study supports the greater contrast caused by the different phase plate absorptions as the main cause of high counts for the AIHA PAT chrysotile slides using the DM objective. The comparison of fiber count ratios (DM/standard) between the AIHA PAT chrysotile samples and chrysotile field samples indicates that there is a fraction of fibers in the PAT samples approaching the theoretical limit of visibility of the phase-contrast microscope with 3-degree phase-shift. These fibers become more clearly visible through the greater contrast from the phase plate absorption of the DM objective. However, as such fibers are not present in field samples, no difference in counts between the two objectives was observed in this study. The DM objective, therefore, could be allowed for routine fiber counting as it will maintain continuity with risk assessments based on earlier phase-contrast microscopy fiber counts from field samples. Published standard methods would need to be modified to allow a higher aperture specification for the objective. PMID:25737333

The influence of Saccharomyces cerevisiae enzyme ratio on preparation virgin coconut oil for candidate in-house reference materials

NASA Astrophysics Data System (ADS)

Rohyami, Yuli; Anjani, Rafika Debby; Purwanti, Napthalina Putri

2017-03-01

Virgin coconut oil is an excellent product which has result of oil processing business opportunities in the international market. Standardization of virgin coconut oil necessary to satisfy the requirements industry needs. This research is expected as procedure preparation of reference materials. Preparation of virgin coconut oil by Sacharomycescerevisiaeenzyme. Based on the results of this study concluded that the ratio of Saccharomyces cerevisiae can affect the yield of virgin coconut oil produced. The preparation of virgin coconut oil enzymatically using a variety of mass ratio of 0.001 to 0.006% is obtained yield average of 12.40%. The optimum separation of virgin coconut oil on the use of enzymes with a mass ratio of 0.002%. The average water content at a ratio of 0.002% is 0.04 % with a value of uncertainty is 0.005%. The average iodine number in virgin coconut oil produced is 2.4403 ± 0,1974 grams of iodine per 100 grams of oil and optimum iodine number is obtained from the manufacturing process virgin coconut oil with a ratio of 0.006% Saccharomyces cerevisiae. Sacharomycescerevisiae with a ratio of 0.002% results virgin coconut oil with acid number 0.3068 ± 0.1098%. The peroxide value of virgin coconut oil between 0.0108 ± 0.009 to 0.0114 ± 0015milli-equivalent per kilograms. Organoleptic test results and test chemical parameters can be used as the test data that can be developed in prototype preparation of candidate in-house reference material in the testing standards of quality virgin coconut oil.

Report planning, preparation and review guide

USGS Publications Warehouse

Moore, J.E.; Aronson, D.A.; Green, J.H.; Puente, Celso

1990-01-01

The guide describes critical steps in the planning, preparation, and review of hydrologic projects and reports. Project and report planning and organization are discussed first. Report writing and guidelines for writing selected parts of the report are covered next. The last topics covered are editorial and technical review. The guide contains examples of good and poor writing, report checklists, and source references to assist authors in the various stages of report preparation.

Chemical Principles of the Biotechnology of the Preparation of Fuel

NASA Astrophysics Data System (ADS)

Varfolomeev, Sergei D.; Kalyuzhnyi, S. V.; Medman, D. Ya

1988-07-01

The chemical aspects of the biotechnology of the preparation of fuels together with the potential resources and possibilities of the biofuel technology are described. The present state of research into the preparation of biogas (mixture of methane and carbon dioxide), ethanol, acetone, butyl alcohol, and hydrogen from the biomass is examined. The technological features and economic aspects of the processes listed above are analysed. The bibliography includes 213 references.

Resonant ultrasound spectroscopy

DOEpatents

Migliori, Albert

1991-01-01

A resonant ultrasound spectroscopy method provides a unique characterization of an object for use in distinguishing similar objects having physical differences greater than a predetermined tolerance. A resonant response spectrum is obtained for a reference object by placing excitation and detection transducers at any accessible location on the object. The spectrum is analyzed to determine the number of resonant response peaks in a predetermined frequency interval. The distribution of the resonance frequencies is then characterized in a manner effective to form a unique signature of the object. In one characterization, a small frequency interval is defined and stepped though the spectrum frequency range. Subsequent objects are similarly characterized where the characterizations serve as signatures effective to distinguish objects that differ from the reference object by more than the predetermined tolerance.

Rapid fast-mapping abilities in 2-year-olds.

PubMed

Spiegel, Chad; Halberda, Justin

2011-05-01

Learning a new word consists of two primary tasks that have often been conflated into a single process: referent selection, in which a child must determine the correct referent of a novel label, and referent retention, which is the ability to store this newly formed label-object mapping in memory for later use. In addition, children must be capable of performing these tasks rapidly and repeatedly as they are frequently exposed to novel words during the course of natural conversation. Here we used a preferential pointing task to investigate 2-year-olds' (N=72) ability to infer the referent of a novel noun from a single ambiguous exposure and their ability to retain this mapping over time. Children were asked to identify the referent of a novel label on six critical trials distributed throughout the course of a 10-min study involving many familiar and novel objects. On these critical trials, images of a known object and a novel object (e.g., a ball and a nameless artifact constructed in the laboratory) appeared on two computer screens and a voice asked children to "point at the _____ [e.g., glark]." Following label onset, children were allowed only 3s during which to infer the correct referent, point at it, and potentially store this new word-object mapping. In a final posttest trial, all previously labeled novel objects appeared and children were asked to point to one of them (e.g., "Can you find the glark?"). To succeed, children needed to have initially mapped the novel labels correctly and retained these mappings over the course of the study. Despite the difficult demands of the current task, children successfully identified the target object on the retention trial. We conclude that 2-year-olds are able to fast map novel nouns during a brief single exposure under ambiguous labeling conditions. Copyright © 2010 Elsevier Inc. All rights reserved.

Efficacy and safety of topical Trikatu preparation in, relieving mosquito bite reactions: a randomized controlled trial.

PubMed

Maenthaisong, Ratree; Chaiyakunapruk, Nathorn; Tiyaboonchai, Waree; Tawatsin, Apiwat; Rojanawiwat, Archawin; Thavara, Usavadee

2014-02-01

Trikatu is composed of dried fruits of Piper nigrum L and Piper retrofractum Vahl, and dried rhizomes of Zingiber officinale R. Although this preparation has been used to relieve pruritis, pain, and inflammation for a long time, there is no clinical evidence to confirm its efficacy and safety. Therefore, we performed a double-blind, within person-randomized controlled study of 30 healthy volunteers to determine efficacy and safety of topical Trikatu on mosquito bite reactions. All subjects were bitten by Aedes aegypti laboratory mosquitoes on their forearms and they were randomly assigned arms to apply either Trikatu or reference product on the mosquito bite papule. The main outcome was the difference of papule size reduction at 30 min, measured by a caliper, between the Trikatu and reference arms. Pruritis, redness, pain, and patient satisfaction were assessed at 15, 30, 60, 180, and 360 min as secondary outcomes. There were no significant differences between treatment and reference arms on any outcome at any time of measurement. Trikatu did not show additional effects for relieving mosquito bite reaction as compared with the reference product containing camphor, menthol, and eucalyptus. For further study, it is very important to consider a proper selection of subjects, comparator product, and concentration of extract when Trikatu preparation is investigated. Copyright © 2013 Elsevier Ltd. All rights reserved.

Endogenous versus exogenous generic reference pricing for pharmaceuticals.

PubMed

Antoñanzas, F; Juárez-Castelló, C A; Rodríguez-Ibeas, R

2017-12-01

In this paper we carry out a vertical differentiation duopoly model applied to pharmaceutical markets to analyze how endogenous and exogenous generic reference pricing influence competition between generic and branded drugs producers. Unlike the literature, we characterize for the exogenous case the equilibrium prices for all feasible relevant reference prices. Competition is enhanced after the introduction of a reference pricing system. We also compare both reference pricing systems on welfare grounds, assuming two different objective functions for health authorities: (i) standard social welfare and (ii) gross consumer surplus net of total pharmaceutical expenditures. We show that regardless of the objective function, health authorities will never choose endogenous reference pricing. When health authorities are paternalistic, the exogenous reference price that maximizes standard social welfare is such that the price of the generic drug is the reference price while the price of the branded drug is higher than the reference price. When health authorities are not paternalistic, the optimal exogenous reference price is such that the price of the branded drug is the reference price while the price of the generic drug is lower than the reference price.

Varieties of virtualization

NASA Technical Reports Server (NTRS)

Ellis, Stephen R.

1991-01-01

Natural environments have a content, i.e., the objects in them; a geometry, i.e., a pattern of rules for positioning and displacing the objects; and a dynamics, i.e., a system of rules describing the effects of forces acting on the objects. Human interaction with most common natural environments has been optimized by centuries of evolution. Virtual environments created through the human-computer interface similarly have a content, geometry, and dynamics, but the arbitrary character of the computer simulation creating them does not insure that human interaction with these virtual environments will be natural. The interaction, indeed, could be supernatural but it also could be impossible. An important determinant of the comprehensibility of a virtual environment is the correspondence between the environmental frames of reference and those associated with the control of environmental objects. The effects of rotation and displacement of control frames of reference with respect to corresponding environmental references differ depending upon whether perceptual judgement or manual tracking performance is measured. The perceptual effects of frame of reference displacement may be analyzed in terms of distortions in the process of virtualizing the synthetic environment space. The effects of frame of reference displacement and rotation have been studied by asking subjects to estimate exocentric direction in a virtual space.

Resolution enhancement in coherent x-ray diffraction imaging by overcoming instrumental noise.

PubMed

Kim, Chan; Kim, Yoonhee; Song, Changyong; Kim, Sang Soo; Kim, Sunam; Kang, Hyon Chol; Hwu, Yeukuang; Tsuei, Ku-Ding; Liang, Keng San; Noh, Do Young

2014-11-17

We report that reference objects, strong scatterers neighboring weak phase objects, enhance the phase retrieval and spatial resolution in coherent x-ray diffraction imaging (CDI). A CDI experiment with Au nano-particles exhibited that the reference objects amplified the signal-to-noise ratio in the diffraction intensity at large diffraction angles, which significantly enhanced the image resolution. The interference between the diffracted x-ray from reference objects and a specimen also improved the retrieval of the phase of the diffraction signal. The enhancement was applied to image NiO nano-particles and a mitochondrion and confirmed in a simulation with a bacteria phantom. We expect that the proposed method will be of great help in imaging weakly scattering soft matters using coherent x-ray sources including x-ray free electron lasers.

Whisking mechanics and active sensing.

PubMed

Bush, Nicholas E; Solla, Sara A; Hartmann, Mitra Jz

2016-10-01

We describe recent advances in quantifying the three-dimensional (3D) geometry and mechanics of whisking. Careful delineation of relevant 3D reference frames reveals important geometric and mechanical distinctions between the localization problem ('where' is an object) and the feature extraction problem ('what' is an object). Head-centered and resting-whisker reference frames lend themselves to quantifying temporal and kinematic cues used for object localization. The whisking-centered reference frame lends itself to quantifying the contact mechanics likely associated with feature extraction. We offer the 'windowed sampling' hypothesis for active sensing: that rats can estimate an object's spatial features by integrating mechanical information across whiskers during brief (25-60ms) windows of 'haptic enclosure' with the whiskers, a motion that resembles a hand grasp. Copyright © 2016. Published by Elsevier Ltd.

Shrinkage stress compensation in composite-restored teeth: relaxation or hygroscopic expansion?

PubMed

Meriwether, Laurel A; Blen, Bernard J; Benson, Jarred H; Hatch, Robert H; Tantbirojn, Daranee; Versluis, Antheunis

2013-05-01

Polymerization of composite restorations causes shrinkage, which deforms and thus stresses restored teeth. This shrinkage deformation, however, has been shown to decrease over time. The objective was to investigate whether this reduction was caused by hygroscopic expansion or stress relaxation of the composite/tooth complex. Extracted molars were mounted in rigid stainless steel rings with four spherical reference areas. Twelve molars were prepared with large mesioocclusodistal slots, etched, bonded, and restored with a composite material (Filtek Supreme, 3M ESPE) in two horizontal layers. Ten intact molars were the controls. The teeth were stored either in deionized water or silicone oil. They were scanned after preparation (baseline), restoration (0-week), and after 1, 2, and 4 weeks storage. Scanned tooth surfaces were aligned with the baseline using the unchanged reference areas. Cuspal flexure was calculated from lingual and buccal surface deformation. To verify that the restorations had remained bonded, dye penetration at the interfaces was assessed using basic fuchsin dye. Statistical assessment was done by ANOVA followed by Student-Newman-Keuls post hoc test (p=0.05). Substantial cuspal contraction was found for restored teeth after the composite was cured (13-14 μm cuspal flexure). After 4 weeks cuspal contraction decreased significantly for restored teeth stored in water (7.3 ± 3.2) but not for those stored in silicone oil (11.4 ± 5.0). Dye penetration of the occlusal interface was minimal in both groups (106 ± 87 and 21 ± 28 μm in water and silicone oil, respectively). The results suggest that hygroscopic expansion was the main mechanism for shrinkage stress compensation. Copyright © 2013 Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

Identification of rosmarinic acid as the major active constituent in Cordia americana.

PubMed

Geller, F; Schmidt, C; Göttert, M; Fronza, M; Schattel, V; Heinzmann, B; Werz, O; Flores, E M M; Merfort, I; Laufer, S

2010-04-21

Preparation from leaves of Cordia americana have been widely used in traditional medicine in South Brazil to treat wounds and various inflammations. The objective of this work was to identify the effective compounds in the ethanolic extract prepared from the leaves of Cordia americana, which is used in traditional South Brazilian medicine as anti-inflammatory and wound healing remedy. Isolation and structure elucidation techniques were performed in order to identify the compounds of Cordia americana and HPLC analysis was used for the quantification. The major constituent and the ethanolic extract were investigated for inhibition of 5-lipoxygenase, p38alpha MAPK, TNFalpha release and NF-kappaB as well as in the fibroblast scratch assay. Rosmarinic acid (1) was identified as the major compound with an amount of 8.44% in the ethanolic extract of the leaves of Cordia americana. The ethanolic extract as well as (1) exhibited the highest inhibitory effects on 5-lipoxygenase (IC(50)=0.69 and 0.97microg/mL, resp., IC50 of BWA4C as reference: 0.3microM) and p38alpha (IC50=3.25 and 1.16microg/mL, resp., IC50 of SB203580 as reference: 0.046microM) and moderate inhibitory effects on TNFalpha release. Slight effects were observed in the fibroblast scratch assay. This study increases our knowledge on the effective compound in Cordia americana and supports its use in traditional medicine. We demonstrated for the first time pharmacological effects of Cordia americana and we provide evidences for a crucial role of rosmarinic acid as the major key player. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.

A National Survey of U.S. Internists’ Experiences with Ethical Dilemmas and Ethics Consultation

PubMed Central

DuVal, Gordon; Clarridge, Brian; Gensler, Gary; Danis, Marion

2004-01-01

OBJECTIVE To identify the ethical dilemmas that internists encounter, the strategies they use to address them, and the usefulness of ethics consultation. DESIGN National telephone survey. SETTING Doctors’ offices. PARTICIPANTS General internists, oncologists, and critical care/pulmonologists (N = 344, 64% response rate). MEASUREMENTS Types of ethical dilemmas recently encountered and likelihood of requesting ethics consultation; satisfaction with resolution of ethical dilemmas with and without ethics consultation. RESULTS Internists most commonly reported dilemmas regarding end-of-life decision making, patient autonomy, justice, and conflict resolution. General internists, oncologists, and critical care specialists reported participating in an average of 1.4, 1.3, and 4.1 consultations in the preceding 2 years, respectively (P < .0001). Physicians with the least ethics training had the least access to and participated in the fewest ethics consultations; 19% reported consultation was unavailable at their predominant practice site. Dilemmas about end-of-life decisions and patient autonomy were often referred for consultation, while dilemmas about justice, such as lack of insurance or limited resources, were rarely referred. While most physicians thought consultations yielded information that would be useful in dealing with future ethical dilemmas (72%), some hesitated to seek ethics consultation because they believed it was too time consuming (29%), might make the situation worse (15%), or that consultants were unqualified (11%). CONCLUSIONS While most internists recall recent ethical dilemmas in their practices, those with the least preparation and experience have the least access to ethics consultation. Health care organizations should emphasize ethics educational activities to prepare physicians for handling ethical dilemmas on their own and should improve the accessibility and responsiveness of ethics consultation when needed. PMID:15009780

Research notes : evaluation of the performance of reference electrodes embedded in reinforced concrete.

DOT National Transportation Integrated Search

1995-07-01

The objectives of this work were to examine placement strategies for reference electrodes and to evaluate the suitability of graphite reference electrodes as imbedded reference electrodes in reinforced concrete structures that are cathodically protec...

Bibliography of marine radiation ecology prepared for the Seabed Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schultz, V.S.

1980-02-01

References on the effects of ionizing radiation on aquatic organisms have been obtained from a number of sources. Many were obtained from reviews and other publications. Although the primary purpose of preparing this bibliography was to obtain information related to the nuclear wastes Seabed Disposal Biology Program of Sandia Laboratories, freshwater organisms are included as a matter of convenience and also with the belief that such a bibliography would be of interest to a wider audience than that restricted to the Seabed Program. While compilation of a list in an area broad in scope is often somewhat arbitrary, an attemptmore » was made to reference publications that were related to field or laboratory studies of wild species of plants and animals with respect to radiation effects. Complete information concerning each reference are provided without excessive library search. Since one often finds references listed in the literature that are incompletely cited, it was not always possible to locate the reference for verification or completion of the citation. Such references are included where they appeared to be of possible value. When known, a reference is followed with its Nuclear Science Abstract designation, or rarely other abstract sources. Those desiring additional information should check Nuclear Science Abstracts utilizing the abstract number presented or other abstracting sources. In addition, the language of the article, other than English, is given when it is known to me.« less

Discovering Historic Iowa. American Revolution Bicentennial Edition.

ERIC Educational Resources Information Center

Pratt, LeRoy G.

Prepared in recognition of the Bicentennial, this historic guide of Iowa is intended to supplement materials prepared by the Iowa Curriculum Division. It provides, in one convenient reference, information for use by teachers, students, tourists, and others interested in Iowa's history. Up-to-date information is given on historical societies,…

Management Preparation and Training of Department Heads in ARL Libraries.

ERIC Educational Resources Information Center

Wittenbach, Stefanie A.; And Others

1992-01-01

A survey of cataloging and reference department heads in ARL (Association for Research Libraries) member libraries showed that both professional experience and management coursework play a part in a librarian's promotion to department head. It is suggested that library management will improve if libraries require formal management preparation and…

HANDBOOK FOR PREPARING OFFICE OF RESEARCH AND DEVELOPMENT REPORTS (EPA/600/K-95/002)

EPA Science Inventory

This Handbook is intended to assist authors and editors when preparing documents that report the results and conclusions of ORD's research, development, and demon-stration programs. The Handbook contains a listing of reference documents to be used in writing a report, a discuss...

[Reference citation].

PubMed

Brkić, Silvija

2013-01-01

Scientific and professional papers represent the information basis for scientific research and professional work. References important for the paper should be cited within the text, and listed at the end of the paper. This paper deals with different styles of reference citation. Special emphasis was placed on the Vancouver Style for reference citation in biomedical journals established by the International Committee of Medical Journal Editors. It includes original samples for citing various types of articles, both printed and electronic, as well as recommendations related to reference citation in accordance with the methodology and ethics of scientific research and guidelines for preparing manuscripts for publication.

ALT-114 and ALT-118 Alternative Approaches to NIST-Traceable Reference Gases

EPA Science Inventory

In 2016, US EPA approved two separate alternatives (ALT 114 and ALT 118) for the preparation and certification of Hydrogen Chloride (HCl) and Mercury (Hg) cylinder reference gas standards that can serve as EPA Protocol gases where EPA Protocol are required, but unavailable. The a...

Proposed Oral Reference Dose (RfD) for Barium and Compounds (Final Report, 2004)

EPA Science Inventory

This document is the final report from the 2004 external peer review of the Proposed Oral Reference Dose (RfD) for Barium and Compounds, prepared by the U.S. Environmental Protection Agency (EPA), National Center for Environmental Assessment (NCEA), for the Integrated Risk...

Sourcebook for Biological Sciences.

ERIC Educational Resources Information Center

Troyer, Donald L.; And Others

This is a reference book of curriculum and multimedia materials, equipment and supplies, professional references, and auxiliary resource material. This sourcebook attempts to meet the needs of the classroom biology teacher and is a direct response to the many questions and concerns of both biology teachers and those preparing to become teachers.…

Effluent Monitoring Procedures: Nutrients. Student Reference Manual.

ERIC Educational Resources Information Center

Environmental Protection Agency, Washington, DC. Office of Water Programs.

This is one of several short-term courses developed to assist in the training of waste water treatment plant operational personnel in the tests, measurements, and report preparation required for compliance with their NPDES Permits. The Student Reference Manual provides step-by-step procedures for laboratory application of equipment operating…

42 CFR 7.5 - Payment procedures.

Code of Federal Regulations, 2014 CFR

2014-10-01

... REFERENCE BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.5 Payment procedures. An up-to-date fee..., Centers for Disease Control and Prevention, 1600 Clifton Road, MS C-17, Atlanta, Georgia 30333 or 404-639... in U.S. dollars at the time that the requester requests the biological reference standard or...

42 CFR 7.5 - Payment procedures.

Code of Federal Regulations, 2013 CFR

2013-10-01

... REFERENCE BIOLOGICAL STANDARDS AND BIOLOGICAL PREPARATIONS § 7.5 Payment procedures. An up-to-date fee..., Centers for Disease Control and Prevention, 1600 Clifton Road, MS C-17, Atlanta, Georgia 30333 or 404-639... in U.S. dollars at the time that the requester requests the biological reference standard or...

Effluent Monitoring Procedures: Metals Analyses. Student Reference Manual.

ERIC Educational Resources Information Center

Environmental Protection Agency, Washington, DC. Office of Water Programs.

This is one of several short-term courses developed to assist in the training of waste water treatment plant operational personnel in the tests, measurements, and report preparation required for compliance with their NPDES Permits. The Student Reference Manual provides step-by-step procedures for laboratory application of equipment operating…

Assisting Your Preservice Teacher to Be Successful during Field Experiences

ERIC Educational Resources Information Center

Brett, Christine

2006-01-01

Field experience (junior practicum and student teaching) is considered by many to be the most influential part of a teacher preparation program (Cruickshank & Aramalin, 1986; Tannehill & Zakrajsek, 1988). During field experiences, preservice teachers (hereafter referred to as PSTs) are guided by a cooperating teacher (hereafter referred to as a…

Carbon isotope ratios of nandrolone, boldenone, and testosterone preparations seized in Norway compared to those of endogenously produced steroids in a Nordic reference population.

PubMed

Hullstein, Ingunn; Sagredo, Carlos; Hemmersbach, Peter

2014-01-01

Determining the origin of anabolic androgenic steroids (AAS) that also are produced endogenously in the human body is a major issue in doping control. In some cases, the presence of nandrolone and boldenone metabolites might result from endogenous production. The GC-C-IRMS technique (gas chromatography-combustion-isotope ratio mass spectrometry) enables the carbon isotopic ratio (CIR) to be measured to determine the origin of these metabolites. The aim of this study was to use GC-C-IRMS to determine the δ(13) CVPDB values of seized boldenone and nandrolone preparations to decide if the steroids themselves were depleted in (13) C, compared to what is normally seen in endogenously produced steroids. In addition, several testosterone preparations were analyzed. A total of 69 seized preparations were analyzed. The nandrolone preparations showed δ(13) CVPDB values in the range of -31.5 ‰ to -26.7 ‰. The boldenone preparations showed δ(13) CVPDB values in the range of -32.0 ‰ to -27.8 ‰, and for comparison the testosterone preparations showed δ(13) CVPDB values of -31.0 ‰ to -24.2 ‰. The results showed that the values measured in the nandrolone and boldenone preparations were in the same range as those measured in the testosterone preparations. The study also included measurements of CIR of endogenously produced steroids in a Norwegian/Danish reference population. The δ(13) CVPDB values measured for the endogenous steroids in this population were in the range of -21.7 to -26.8. In general, most of the preparations investigated in this study show (13) C-depleted delta values compared to endogenously produced steroids reflecting a northern European diet. Copyright © 2014 John Wiley & Sons, Ltd.

Development of potential candidate reference materials for drugs in bottom sediment, cod and herring tissues.

PubMed

Baranowska, Irena; Buszewski, Bogusław; Namieśnik, Jacek; Konieczka, Piotr; Magiera, Sylwia; Polkowska-Motrenko, Halina; Kościelniak, Paweł; Gadzała-Kopciuch, Renata; Woźniakiewicz, Aneta; Samczyński, Zbigniew; Kochańska, Kinga; Rutkowska, Małgorzata

2017-02-01

Regular use of a reference material and participation in a proficiency testing program can improve the reliability of analytical data. This paper presents the preparation of candidate reference materials for the drugs metoprolol, propranolol, carbamazepine, naproxen, and acenocoumarol in freshwater bottom sediment and cod and herring tissues. These reference materials are not available commercially. Drugs (between 7 ng/g and 32 ng/g) were added to the samples, and the spiked samples were freeze-dried, pulverized, sieved, homogenized, bottled, and sterilized by γ-irradiation to prepare the candidate materials. Procedures for extraction and liquid chromatography coupled with tandem mass spectrometry were developed to determine the drugs of interest in the studied material. Each target drug was quantified using two analytical procedures, and the results obtained from these two procedures were in good agreement with each other. Stability and homogeneity assessments were performed, and the relative uncertainties due to instability (for an expiration date of 12 months) and inhomogeneity were 10-25% and 4.0-6.8%, respectively. These procedures will be useful in the future production of reference materials. Copyright © 2016 Elsevier Ltd. All rights reserved.

Spatial resolution in visual memory.

PubMed

Ben-Shalom, Asaf; Ganel, Tzvi

2015-04-01

Representations in visual short-term memory are considered to contain relatively elaborated information on object structure. Conversely, representations in earlier stages of the visual hierarchy are thought to be dominated by a sensory-based, feed-forward buildup of information. In four experiments, we compared the spatial resolution of different object properties between two points in time along the processing hierarchy in visual short-term memory. Subjects were asked either to estimate the distance between objects or to estimate the size of one of the objects' features under two experimental conditions, of either a short or a long delay period between the presentation of the target stimulus and the probe. When different objects were referred to, similar spatial resolution was found for the two delay periods, suggesting that initial processing stages are sensitive to object-based properties. Conversely, superior resolution was found for the short, as compared with the long, delay when features were referred to. These findings suggest that initial representations in visual memory are hybrid in that they allow fine-grained resolution for object features alongside normal visual sensitivity to the segregation between objects. The findings are also discussed in reference to the distinction made in earlier studies between visual short-term memory and iconic memory.

Red palm oil-supplemented and biofortified cassava gari increase the carotenoid and retinyl palmitate concentrations of triacylglycerol-rich plasma in women

PubMed Central

Zhu, Chenghao; Cai, Yimeng; Gertz, Erik R.; La Frano, Michael R.; Burnett, Dustin J.; Burri, Betty J.

2016-01-01

Boiled biofortified cassava containing β-carotene can increase retinyl palmitate in triacylglycerol-rich plasma. Thus, it might alleviate vitamin A deficiency. Cassava requires extensive preparation to decrease its level of cyanogenic glucosides, which can be fatal. Garification is a popular method of preparing cassava that removes cyanogen glucosides. Our objective was to compare the effectiveness of biofortified gari to gari prepared with red palm oil. The study was a randomized cross-over trial in 8 American women. Three gari preparations separated by 2 wk washout periods were consumed. Treatments (containing 200 – 225.9 g gari) were: biofortified gari (containing 1 mg β-carotene); red palm oil-fortified gari (1 mg β-carotene), and unfortified gari with a 0.3 mg retinyl palmitate reference dose. Blood was collected six times from −0.5 – 9.5 h post-ingestion. Triacylglycerol-rich plasma was separated by ultracentrifugation and analyzed by HPLC with diode array detection. Area under the curve for β-carotene, α-carotene, and retinyl palmitate increased after the fortified meals were fed (P < 0.05), though the retinyl palmitate increase induced by the red palm oil treatment was greater than that induced by the biofortified treatment (p<0.05). Vitamin A conversion was 2.4 ± 0.3 and 4.2 ± 1.5 μg pro-vitamin A carotenoid:1 μg retinol (means ± SEM) for red palm oil and biofortified gari, respectively. These results show that both treatments increased β-carotene, α-carotene, and retinyl palmitate in triacylglycerol-rich plasma concentrations in healthy well- nourished adult women, supporting our hypothesis that both interventions could support efforts to alleviate vitamin A deficiency. PMID:26319612

Consumer’s Perception on Design and Layout of Consumer Medical Information Leaflets on Obesity and Lipid Lowering Drugs

PubMed Central

Mathew, Elizabeth M.; Rajiah, Kingston; Sharma, Krishana Kumar

2013-01-01

Background: Printed education materials are often used to augment healthcare professional’s verbal information to consumers so it serves as an important component of symptom management. They also enhance the teaching process and can be used by consumers as a home reference. Objective: This study was aimed to interpret consumers’ perception on Consumer Medical Information Leaflets (CMILs) on obesity and lipid lowering drugs, on design and layout using the standard method such as Baker Able Leaflet Design (BALD). Material and Methods: Convenience sampling was done. The study was conducted over a period of 3 years in community pharmacy settings in Tamil Nadu, India. The Consumer Medical Information Leaflets (CMILs) were randomly collected from different community pharmacies. Total of 19 CMILs which are commonly used by the consumers were collected and CMILs were assessed using BALD assessment tool Results: According to BALD assessment (46.28%) leaflets were rated as ‘above standard’ and (53.72) leaflets were rated as ‘standard or poor’ in layout and design since their scores were less than 25. This shows that this issue may be important from the patient’s perspective, which may discourage patient from actually reading the CMILs. Conclusion: In India, generally CMILs are continued to be prepared in English and with higher proportion of consumers with English illiteracy. CMILs, which are prepared without taking consideration of reading level of consumers and proper layout and design, may not achieve the intended purpose. This is an important aspect that any company has to reckon while preparing leaflets and at least in some major local languages in which CMILs have to be prepared. PMID:24551641

Red palm oil-supplemented and biofortified cassava gari increase the carotenoid and retinyl palmitate concentrations of triacylglycerol-rich plasma in women.

PubMed

Zhu, Chenghao; Cai, Yimeng; Gertz, Erik R; La Frano, Michael R; Burnett, Dustin J; Burri, Betty J

2015-11-01

Boiled biofortified cassava containing β-carotene can increase retinyl palmitate in triacylglycerol-rich plasma. Thus, it might alleviate vitamin A deficiency. Cassava requires extensive preparation to decrease its level of cyanogenic glucosides, which can be fatal. Garification is a popular method of preparing cassava that removes cyanogen glucosides. Our objective was to compare the effectiveness of biofortified gari to gari prepared with red palm oil. The study was a randomized crossover trial in 8 American women. Three gari preparations separated by 2-week washout periods were consumed. Treatments (containing 200-225.9 g gari) were as follows: biofortified gari (containing 1 mg β-carotene), red palm oil-fortified gari (1 mg β-carotene), and unfortified gari with a 0.3-mg retinyl palmitate reference dose. Blood was collected 6 times from -0.5 to 9.5 hours after ingestion. Triacylglycerol-rich plasma was separated by ultracentrifugation and analyzed by high-performance liquid chromatography (HPLC) with diode array detection. Area under the curve for β-carotene, α-carotene, and retinyl palmitate increased after the fortified meals were fed (P < .05), although the retinyl palmitate increase induced by the red palm oil treatment was greater than that induced by the biofortified treatment (P < .05). Vitamin A conversion was 2.4 ± 0.3 and 4.2 ± 1.5 μg pro-vitamin A carotenoid/1 μg retinol (means ± SEM) for red palm oil and biofortified gari, respectively. These results show that both treatments increased β-carotene, α-carotene, and retinyl palmitate in triacylglycerol-rich plasma concentrations in healthy well-nourished adult women, supporting our hypothesis that both interventions could support efforts to alleviate vitamin A deficiency. Published by Elsevier Inc.

Preparing for the Market. Teacher Edition. Fashion Buying Series.

ERIC Educational Resources Information Center

Collins, Cindy

This teacher's guide presents material for a unit on preparing for the retail fashion market. Content focuses on merchandise plans, computing open-to-buy, computing turnover, the components of a model stock plan, and criteria used when selecting a supplier. The guide contains 5 objectives, 6 group learning activities keyed to the objectives, 21…

Using a Review Book to Improve Knowledge Retention

ERIC Educational Resources Information Center

Elmas, Ridvan; Aydogdu, Bülent; Saban, Yakup

2017-01-01

This study has two primary objectives. The first one is preparation of an efficient review book including a series of activities, which will help fourth grade students exercise what they learned in the elementary science course in a year. The second objective is examination of the prepared book in the framework of student and teacher opinions. In…

Emerging Crucial Issues for School and Society.

ERIC Educational Resources Information Center

Allen, Dwight W.

This monograph contends that education in the future can best prepare students to deal with pressing social issues if it works toward three major objectives. These objectives are: (1) to prepare people to live according to a productive work ethic in which work and leisure pursuits are balanced; (2) to instill in students a life ethic in which…

Volume-labeled nanoparticles and methods of preparation

DOEpatents

Wang, Wei; Gu, Baohua; Retterer, Scott T; Doktycz, Mitchel J

2015-04-21

Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.

Systems and methods that generate height map models for efficient three dimensional reconstruction from depth information

DOEpatents

Frahm, Jan-Michael; Pollefeys, Marc Andre Leon; Gallup, David Robert

2015-12-08

Methods of generating a three dimensional representation of an object in a reference plane from a depth map including distances from a reference point to pixels in an image of the object taken from a reference point. Weights are assigned to respective voxels in a three dimensional grid along rays extending from the reference point through the pixels in the image based on the distances in the depth map from the reference point to the respective pixels, and a height map including an array of height values in the reference plane is formed based on the assigned weights. An n-layer height map may be constructed by generating a probabilistic occupancy grid for the voxels and forming an n-dimensional height map comprising an array of layer height values in the reference plane based on the probabilistic occupancy grid.

[Research on survey analysis and development strategies of traditional Chinese preparations in Guangdong Province hospitals].

PubMed

Wang, Wen-ming; Yan, Zhen; Liu, Han-jiang; Zhang, Lei-hong; Xia, Li; Zhao, Zhen-dong

2013-12-01

To provide reference for the government to formulate policies and medical institution to formulate development plan, the present situation of medical institutions of traditional Chinese preparation and some countermeasures for developing the research of traditional Chinese preparation in Guangdong province were studied. Combined with development situation of traditional Chinese preparation of medical institutions in Guangdong province in recent years, the development countermeasure of traditional Chinese preparation was discussed. In order to promote the development of traditional Chinese preparation of medical institutions, suggestions and countermeasures for the government and related departments were proposed. Government departments should formulate policies to support the development of traditional Chinese preparation, the medical institutions should make scientific development planning, strengthen the construction of hardware and software and develop special traditional Chinese preparation to promote the healthy development of traditional Chinese preparation.

A Profession Without Limits: The Changing Role of Reference Librarians.

PubMed

Sullo, Elaine; Gomes, Alexandra W

2016-01-01

Reference librarians, specifically those working in academic health sciences environments, have expanded their roles and taken on new and unique responsibilities. While librarians at The George Washington University's Himmelfarb Health Sciences Library continue to provide traditional reference services, they have gone beyond their comfort zone in many cases to become involved in activities that are outside of the librarian's established role. This article describes the current roles of Himmelfarb's reference librarians, as well as the way these librarians prepared for these roles and addressed the associated challenges.

Polyacrylate microspheres composite for all-solid-state reference electrodes.

PubMed

Kisiel, Anna; Donten, Mikołaj; Mieczkowski, Józef; Rius-Ruiz, F Xavier; Maksymiuk, Krzysztof; Michalska, Agata

2010-09-01

A novel concept is proposed for the encapsulation of components within polyacrylate microspheres, prior to their incorporation into a membrane phase. Thus finer and better controlled dispersion of heterogeneous membrane components can be achieved. This concept was verified by using a poly(n-butyl acrylate) membrane-based reference electrode as an example. In this example the proper dispersion of solid constituents of the heterogeneous membrane and prevention of their leakage are both of primary importance. Potassium chloride-loaded poly(n-butyl acrylate) microspheres were prepared and then left in contact with silver nitrate to convert some of the KCl into AgCl. The material obtained was introduced into a poly(n-butyl acrylate) membrane. The reference electrode membranes obtained in this way were characterized with much more stable potential (both in different electrolytes and over time) compared with electrodes prepared by the direct introduction of KCl and AgCl to the membrane.

Bioavailability of ambroxol sustained release preparations. Part II: Single and multiple oral dose studies in man.

PubMed

Janssen, T J; Guelen, P J; Vree, T B; Botterblom, M H; Valducci, R

1988-01-01

The bioavailability of a new ambroxol sustained release preparation (75 mg) based on a dialyzing membrane for controlled release was studied in healthy volunteers after single and multiple oral dose in comparison with a standard sustained release formulation in a cross-over study under carefully controlled conditions. Plasma concentrations of ambroxol were measured by means of a HPLC method. Based on AUC data both preparations are found to be bioequivalent, but show different plasma concentration profiles. The test preparation showed a more pronounced sustained release profile than the reference preparation (single dose) resulting in significantly higher steady state plasma levels.

An ERP Study on Self-Relevant Object Recognition

ERIC Educational Resources Information Center

Miyakoshi, Makoto; Nomura, Michio; Ohira, Hideki

2007-01-01

We performed an event-related potential study to investigate the self-relevance effect in object recognition. Three stimulus categories were prepared: SELF (participant's own objects), FAMILIAR (disposable and public objects, defined as objects with less-self-relevant familiarity), and UNFAMILIAR (others' objects). The participants' task was to…

Role of orientation reference selection in motion sickness

NASA Technical Reports Server (NTRS)

Peterka, Robert J.; Black, F. Owen

1987-01-01

The objectives of this proposal were developed to further explore and quantify the orientation reference selection abilities of subjects and the relation, if any, between motion sickness and orientation reference selection. The overall objectives of this proposal are to determine (1) if motion sickness susceptibility is related to sensory orientation reference selection abilities of subjects, (2) if abnormal vertical canal-otolith function is the source of these abnormal posture control strategies and if it can be quantified by vestibular and oculomotor reflex measurements, and (3) if quantifiable measures of perception of vestibular and visual motion cues can be related to motion sickness susceptibility and to orientation reference selection ability demonstrated by tests which systematically control the sensory imformation available for orientation.

Preparation and Use of Polish Mushroom Proficiency Testing Materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Polkowska-Motrenko, Halina

2008-08-14

Mushroom reference materials have been prepared and characterized for the use in proficiency tests according to a procedure established within the frame of an IAEA Interregional Technical Cooperation Project. The materials were used for conducting the proficiency tests in Poland in 2005-2007. The results obtained by participating laboratories are presented and discussed.

Oregon & Federal Basic Income Tax Return Preparation. Student's Manual 1981.

ERIC Educational Resources Information Center

Young, Donna, Ed.

This student manual contains materials for a 20-session course in basic income tax preparation. Each session may include some or all of these components: a reading assignment, a vocabulary list, interview questions pertinent to that session's subject matter, informative/reference materials, problems to work out in class or at home, exercises, and…

Teacher Prep 3.0: A Vision for Teacher Education to Impact Social Transformation

ERIC Educational Resources Information Center

Kretchmar, Kerry; Zeichner, Ken

2016-01-01

Teacher education in the USA is composed of both defenders and critics of the current system of teacher preparation. Some critics of college and university-based teacher education who describe themselves as "reformers" have referred to the non-university programmes as "teacher preparation 2.0" in order to emphasise the…

Preparing Undergraduate Students for the Major Field Test in Business

ERIC Educational Resources Information Center

Bisalski, Heather Cooper; Helms, Marilyn M.; Whitesell, Melissa

2017-01-01

Many business programs address the learning of undergraduate students with an exit exam. A reference librarian and the business school faculty created an online test preparation study guide (or LibGuide) which included no-cost resources that were readily available yet academically authoritative to aid students in studying for the Educational…

29 CFR 780.910 - Engagement in transportation and preparation.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Engagement in transportation and preparation. 780.910... Requirements Under Section 13(b)(16) Exempt Operations on Fruits Or Vegetables § 780.910 Engagement in... activities, an employee who engages in both is performing exempt work. In referring to “the transportation...

29 CFR 780.910 - Engagement in transportation and preparation.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 3 2011-07-01 2011-07-01 false Engagement in transportation and preparation. 780.910... Requirements Under Section 13(b)(16) Exempt Operations on Fruits Or Vegetables § 780.910 Engagement in... activities, an employee who engages in both is performing exempt work. In referring to “the transportation...

SUPERFUND TREATABILITY CLEARINGHOUSE: CERCLA BDAT SARM PREPARATION AND RESULTS OF PHYSICAL SOILS WASHING EXPERIMENTS (FINAL REPORT)

EPA Science Inventory

This study reports on the results of work preparing 30,000 Ibs of SARM or synthetic analytical reference matrix, a surrogate Superfund soil containing a vide range of contaminants. It also reports the results ©f bench scale treatability experiments designed to simulate the EP...

Educate at Penn State: Preparing Beginning Teachers with Powerful Digital Tools

ERIC Educational Resources Information Center

Murray, Orrin T.; Zembal-Saul, Carla

2008-01-01

University based teacher education programs are slowly beginning to catch up to other professional programs that use modern digital tools to prepare students to enter professional fields. This discussion looks at how one teacher education program reached the conclusion that students and faculty would use notebook computers. Frequently referred to…

Generating Ground Reference Data for a Global Impervious Surface Survey

NASA Technical Reports Server (NTRS)

Tilton, James C.; De Colstoun, Eric Brown; Wolfe, Robert E.; Tan, Bin; Huang, Chengquan

2012-01-01

We are developing an approach for generating ground reference data in support of a project to produce a 30m impervious cover data set of the entire Earth for the years 2000 and 2010 based on the Landsat Global Land Survey (GLS) data set. Since sufficient ground reference data for training and validation is not available from ground surveys, we are developing an interactive tool, called HSegLearn, to facilitate the photo-interpretation of 1 to 2 m spatial resolution imagery data, which we will use to generate the needed ground reference data at 30m. Through the submission of selected region objects and positive or negative examples of impervious surfaces, HSegLearn enables an analyst to automatically select groups of spectrally similar objects from a hierarchical set of image segmentations produced by the HSeg image segmentation program at an appropriate level of segmentation detail, and label these region objects as either impervious or nonimpervious.

Cervical human papilloma virus (HPV) DNA primary screening test: Results of a population-based screening programme in central Italy.

PubMed

Passamonti, Basilio; Gustinucci, Daniela; Giorgi Rossi, Paolo; Cesarini, Elena; Bulletti, Simonetta; Carlani, Angela; Martinelli, Nadia; Broccolini, Massimo; D'Angelo, Valentina; D'Amico, Maria Rosaria; Di Dato, Eugenio; Galeazzi, Paola; Malaspina, Morena; Spita, Nicoletta; Tintori, Beatrice; Giaimo, Maria Donata

2017-09-01

Objective To present the results of the first and second round human papilloma virus (HPV)-based screening programme in the Umbria region after three years. Methods From August 2010 to November 2011, the entire female population aged 35-64 in a local health district was invited for HPV testing (HPV-DNA cobas4800 on a liquid-based cytology sample). HPV-negative women were re-invited after three years. For HPV-positive women, a slide was prepared and interpreted. Positive cytologies were referred to colposcopy; negatives were referred to repeat HPV after one year. If HPV was persistently positive, women were referred to colposcopy; if negative, to normal screening. Indicators of the first and second round are compared with those of cytology screening in the same area in the preceding three years. Results Participation was 56.5%, the same as cytology (56.6%). HPV-positivity was 6.4% (396/6272), cytology triage positivity was 35.6%; 251 cytology negative women were referred to one-year HPV retesting, 84.1% complied, and 55.5% were positive. Total colposcopy referral was 4.1%, and for cytology 1%. The detection rate for cervical intraepithelial neoplasia grade 2 or more severe was 10‰, compared with 3.7‰ using cytology. After three years, HPV-positivity was 3.4% (129/3831), overall colposcopy referral was 2.3% (most at one-year follow-up), and detection rate was 0.5/1000. Conclusions The first round detection rate was more than twice that of cytology screening, while colposcopy referral increased fourfold. At the second round, the detection rate decreased dramatically, showing that longer interval and more conservative protocols are needed.

Standardization of allergen products: 2. Detailed characterization of GMP-produced recombinant Phl p 5.0109 as European Pharmacopoeia reference standard.

PubMed

Himly, M; Nandy, A; Kahlert, H; Thilker, M; Steiner, M; Briza, P; Neubauer, A; Klysner, S; van Ree, R; Buchheit, K-H; Vieths, S; Ferreira, F

2016-04-01

The Biological Standardization Programme of the European Directorate for Quality of Medicines and Healthcare (EDQM) aims at the establishment of well-characterized reference standards based on recombinant allergens and validated assays for the quantification of major allergen content. The objective of this study was to examine the detailed physicochemical and immunological characterization of recombinant Phl p 5.0109, the second available allergen reference standard. Recombinant Phl p 5.0109 PP5ar06007 was produced under GMP conditions and analyzed by an array of physicochemical and immunological methods for identity, quantity, homogeneity, and folding stability in bulk solution, as well as thermal denaturation, aggregation state, and biological activity when formulated for long-time storage. PP5ar06007 revealed as a highly homogeneous, monomeric, well-folded preparation of rPhl p 5.0109, as documented by mass spectrometry, SDS-PAGE, isoelectric focusing, size-exclusion chromatography with light scattering, circular dichroism, and infrared spectroscopy. Upon storage at +4°C, PP5ar06007 retained the monomeric state for at least 2 months. A protein quantity of 1.56 ± 0.03 mg/ml was determined by amino acid analysis in PP5ar06007, and its biological activity was shown to be comparable to natural Phl p 5 in terms of basophil activation and T-cell reactivity. Recombinant Phl p 5.0109 PP5ar06007 was characterized extensively at the physicochemical and immunological level. It revealed to be a highly stable, monomeric, and immunologically equivalent of its natural counterpart. PP5ar06007 is now available as European Pharmacopoeia allergen reference standard for grass pollen products. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Frames of Reference in Spatial Memories Acquired From Language

ERIC Educational Resources Information Center

Mou, Weimin; Zhang, Kan; McNamara, Timothy P.

2004-01-01

Four experiments examined reference systems in spatial memories acquired from language. Participants read narratives that located 4 objects in canonical (front, back, left, right) or noncanonical (left front, right front, left back, right back) positions around them. Participants' focus of attention was first set on each of the 4 objects, and then…

Off-axis illumination direct-to-digital holography

DOEpatents

Thomas, Clarence E.; Price, Jeffery R.; Voelkl, Edgar; Hanson, Gregory R.

2004-06-08

Systems and methods are described for off-axis illumination direct-to-digital holography. A method of recording an off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis, includes: reflecting a reference beam from a reference mirror at a non-normal angle; reflecting an object beam from an object at an angle with respect to an optical axis defined by a focusing lens; focusing the reference beam and the object beam at a focal plane of a digital recorder to form the off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; digitally recording the off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes for Fourier analysis; Fourier analyzing the recorded off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes by transforming axes of the recorded off-axis illuminated spatially heterodyne hologram including spatially heterodyne fringes in Fourier space to sit on top of a heterodyne carrier frequency defined as an angle between the reference beam and the object beam; applying a digital filter to cut off signals around an original origin; and then performing an inverse Fourier transform.

Eliminating the use of intravenous glass bottles using a FOCUS-PDCA model and providing a practical stability reference guide.

PubMed

Maraiki, Fatma; Farooq, Faiyaz; Ahmed, Mohamed

2016-08-01

To identify the intravenous (IV) medications that are prepared in glass bottles at the institution and establish which of these medications can be prepared in flexible IV bags such as polyvinyl chloride (PVC) or non-PVC instead of glass bottles. The cost implication of switching from glass bottles to flexible IV bags was calculated. A study using FOCUS-PDCA model to identify IV medications prepared in glass bottles and establish which of these medications could be prepared in IV bags (PVC or non-PVC). The cost impact of switching from glass bottles to IV plastic bags (including PVC or non-PVC) was calculated. The stability data obtained were used as a reference for updating pharmacy internal IV preparation charts. A total of 17 IV medications were found to be prepared in IV glass bottles. Of these 17 medications, only 8 (47%) were prepared in IV glass bottles due to incompatibility with PVC bags. For 7 (41%) of the medications, of which 6 were monoclonal antibodies (MABs), the reason for preparation in glass bottles was unclear as these medications are compatible with either PVC or non-PVC or both. The potential cost savings associated with switching all of the identified medications to IV plastic bags (either non-PVC or PVC) exceeded $200 000. The elimination of glass bottles within the institution resulted in a significant cost saving. The use of FOCUS-PDCA model can help healthcare institution achieve significant improvements in process and realize significant cost savings. © 2016 Royal Pharmaceutical Society.

[Study on ethnic medicine quantitative reference herb,Tibetan medicine fruits of Capsicum frutescens as a case].

PubMed

Zan, Ke; Cui, Gan; Guo, Li-Nong; Ma, Shuang-Cheng; Zheng, Jian

2018-05-01

High price and difficult to get of reference substance have become obstacles to HPLC assay of ethnic medicine. A new method based on quantitative reference herb (QRH) was proposed. Specific chromatograms in fruits of Capsicum frutescens were employed to determine peak positions, and HPLC quantitative reference herb was prepared from fruits of C. frutescens. The content of capsaicin and dihydrocapsaicin in the quantitative control herb was determined by HPLC. Eleven batches of fruits of C. frutescens were analyzed with quantitative reference herb and reference substance respectively. The results showed no difference. The present method is feasible for quality control of ethnic medicines and quantitative reference herb is suitable to replace reference substances in assay. Copyright© by the Chinese Pharmaceutical Association.

Hearing Tests on Mobile Devices: Evaluation of the Reference Sound Level by Means of Biological Calibration.

PubMed

Masalski, Marcin; Kipiński, Lech; Grysiński, Tomasz; Kręcicki, Tomasz

2016-05-30

Hearing tests carried out in home setting by means of mobile devices require previous calibration of the reference sound level. Mobile devices with bundled headphones create a possibility of applying the predefined level for a particular model as an alternative to calibrating each device separately. The objective of this study was to determine the reference sound level for sets composed of a mobile device and bundled headphones. Reference sound levels for Android-based mobile devices were determined using an open access mobile phone app by means of biological calibration, that is, in relation to the normal-hearing threshold. The examinations were conducted in 2 groups: an uncontrolled and a controlled one. In the uncontrolled group, the fully automated self-measurements were carried out in home conditions by 18- to 35-year-old subjects, without prior hearing problems, recruited online. Calibration was conducted as a preliminary step in preparation for further examination. In the controlled group, audiologist-assisted examinations were performed in a sound booth, on normal-hearing subjects verified through pure-tone audiometry, recruited offline from among the workers and patients of the clinic. In both the groups, the reference sound levels were determined on a subject's mobile device using the Bekesy audiometry. The reference sound levels were compared between the groups. Intramodel and intermodel analyses were carried out as well. In the uncontrolled group, 8988 calibrations were conducted on 8620 different devices representing 2040 models. In the controlled group, 158 calibrations (test and retest) were conducted on 79 devices representing 50 models. Result analysis was performed for 10 most frequently used models in both the groups. The difference in reference sound levels between uncontrolled and controlled groups was 1.50 dB (SD 4.42). The mean SD of the reference sound level determined for devices within the same model was 4.03 dB (95% CI 3.93-4.11). Statistically significant differences were found across models. Reference sound levels determined in the uncontrolled group are comparable to the values obtained in the controlled group. This validates the use of biological calibration in the uncontrolled group for determining the predefined reference sound level for new devices. Moreover, due to a relatively small deviation of the reference sound level for devices of the same model, it is feasible to conduct hearing screening on devices calibrated with the predefined reference sound level.

Implementing system simulation of C3 systems using autonomous objects

NASA Technical Reports Server (NTRS)

Rogers, Ralph V.

1987-01-01

The basis of all conflict recognition in simulation is a common frame of reference. Synchronous discrete-event simulation relies on the fixed points in time as the basic frame of reference. Asynchronous discrete-event simulation relies on fixed-points in the model space as the basic frame of reference. Neither approach provides sufficient support for autonomous objects. The use of a spatial template as a frame of reference is proposed to address these insufficiencies. The concept of a spatial template is defined and an implementation approach offered. Discussed are the uses of this approach to analyze the integration of sensor data associated with Command, Control, and Communication systems.

Teacher Self-Efficacy, Burnout, Experience and Decision to Refer a Disruptive Student

ERIC Educational Resources Information Center

Egyed, Carla J.; Short, Rick Jay

2006-01-01

The purpose of this study was to investigate teacher characteristics that may lead to special education referrals, including efficacy, burnout, experience, and preparation. We hypothesized that likelihood to refer for special education is related to these teacher characteristics. This study involved 106 elementary teachers who rated themselves on…

Self-Monitoring Procedures: Basic Parameters for Municipal Effluents. Student Reference Manual.

ERIC Educational Resources Information Center

Environmental Protection Agency, Washington, DC. Office of Water Programs.

This is one of several short-term courses developed to assist in the training of waste water treatment plant operational personnel in the tests, measurements, and report preparation required for compliance with their NPDES Permits. The Student Reference Manual provides step-by-step procedures for laboratory application of equipment operating…

Effluent-Monitoring Procedures: Basic Laboratory Skills. Student Reference Manual.

ERIC Educational Resources Information Center

Engel, William T.; And Others

This is one of several short-term courses developed to assist in the training of waste water treatment plant operational personnel in the tests, measurements, and report preparation required for compliance with their NPDES Permits. This Student Reference Manual provides a review of basic mathematics as it applies to the chemical laboratory. The…

40 CFR 60.711 - Definitions, symbols, and cross reference tables.

Code of Federal Regulations, 2011 CFR

2011-07-01

... audio or video recording or information storage. (14) Natural draft opening means any opening in a room... control device. (18) Utilize refers to the use of solvent that is delivered to coating mix preparation... participate in atmospheric photochemical reactions or that are measured by Method 18, 24, 25, or 25A or an...

40 CFR 60.711 - Definitions, symbols, and cross reference tables.

Code of Federal Regulations, 2013 CFR

2013-07-01

... audio or video recording or information storage. (14) Natural draft opening means any opening in a room... control device. (18) Utilize refers to the use of solvent that is delivered to coating mix preparation... participate in atmospheric photochemical reactions or that are measured by Method 18, 24, 25, or 25A or an...

40 CFR 60.711 - Definitions, symbols, and cross reference tables.

Code of Federal Regulations, 2012 CFR

2012-07-01

... audio or video recording or information storage. (14) Natural draft opening means any opening in a room... control device. (18) Utilize refers to the use of solvent that is delivered to coating mix preparation... participate in atmospheric photochemical reactions or that are measured by Method 18, 24, 25, or 25A or an...

40 CFR 60.711 - Definitions, symbols, and cross reference tables.

Code of Federal Regulations, 2010 CFR

2010-07-01

... audio or video recording or information storage. (14) Natural draft opening means any opening in a room... control device. (18) Utilize refers to the use of solvent that is delivered to coating mix preparation... participate in atmospheric photochemical reactions or that are measured by Method 18, 24, 25, or 25A or an...

40 CFR 60.711 - Definitions, symbols, and cross reference tables.

Code of Federal Regulations, 2014 CFR

2014-07-01

... audio or video recording or information storage. (14) Natural draft opening means any opening in a room... control device. (18) Utilize refers to the use of solvent that is delivered to coating mix preparation... participate in atmospheric photochemical reactions or that are measured by Method 18, 24, 25, or 25A or an...

Nouns referring to tools and natural objects differentially modulate the motor system.

PubMed

Gough, Patricia M; Riggio, Lucia; Chersi, Fabian; Sato, Marc; Fogassi, Leonardo; Buccino, Giovanni

2012-01-01

While increasing evidence points to a critical role for the motor system in language processing, the focus of previous work has been on the linguistic category of verbs. Here we tested whether nouns are effective in modulating the motor system and further whether different kinds of nouns - those referring to artifacts or natural items, and items that are graspable or ungraspable - would differentially modulate the system. A Transcranial Magnetic Stimulation (TMS) study was carried out to compare modulation of the motor system when subjects read nouns referring to objects which are Artificial or Natural and which are Graspable or Ungraspable. TMS was applied to the primary motor cortex representation of the first dorsal interosseous (FDI) muscle of the right hand at 150 ms after noun presentation. Analyses of Motor Evoked Potentials (MEPs) revealed that across the duration of the task, nouns referring to graspable artifacts (tools) were associated with significantly greater MEP areas. Analyses of the initial presentation of items revealed a main effect of graspability. The findings are in line with an embodied view of nouns, with MEP measures modulated according to whether nouns referred to natural objects or artifacts (tools), confirming tools as a special class of items in motor terms. Additionally our data support a difference for graspable versus non graspable objects, an effect which for natural objects is restricted to initial presentation of items. Copyright © 2011 Elsevier Ltd. All rights reserved.

Comparison of Three Enzyme-Linked Immunosorbent Assays for Detection of Immunoglobulin G Antibodies to Tetanus Toxoid with Reference Standards and the Impact on Clinical Practice▿

PubMed Central

van Hoeven, Karen H.; Dale, Connie; Foster, Phil; Body, Barbara

2008-01-01

Accurate determination of the concentrations of immunoglobulin G (IgG) antibody to tetanus toxoid is important in order to evaluate the immunogenicity of tetanus toxoid vaccines, determine immune competence in individual patients, and measure the prevalence of immunity in populations. The performance of three commercially available enzyme-linked immunosorbent assays (ELISAs) for IgG antibodies to tetanus toxoid were evaluated. Serially diluted NIBSC 76/589 and TE-3 human tetanus IgG immunoglobulin international reference standards were analyzed in quadruplicate using ELISAs manufactured by The Binding Site, Inc. (VaccZyme); Scimedx; and Euroimmun. In addition, IgG antibodies to tetanus toxoid were measured in 83 deidentified serum specimens using each manufacturer's ELISA. Each ELISA provided linear results when evaluated with the reference preparations. The Binding Site ELISA provided results that closely corresponded to the reference preparations (y = 1.09x − 0.08), whereas the Scimedx ELISA gave results that were consistently lower (y = 0.21x − 0.07) and the Euroimmun ELISA gave results that were consistently higher (y = 1.5x + 0.30) than the reference preparation concentrations. Using the recommended cutoff for each ELISA (<0.10 IU/ml), the overall agreement of all of the ELISA methods was 78%. Three of eighty-three (3.6%) human serum samples demonstrated inadequate immunity with all three assays. The Binding Site ELISA yielded nonprotective antibody concentrations in only these 3 samples, whereas 19 samples (22.9%) according to the Scimedx ELISA and 6 samples (7.2%) according to the Euroimmun ELISA demonstrated nonprotective concentrations. The performance characteristics of ELISAs for tetanus immunoglobulin titers were manufacturer dependent, and the differences translated into important disparities in reported results. PMID:18845832

Effects of preparation process on performance of rubber modified asphalt

NASA Astrophysics Data System (ADS)

Liu, Hanbing; Luo, Guobao; Wang, Xianqiang; Jiao, Yubo

2015-06-01

The rational utilization of waste rubber tire is essential for the environmental protection. Utilizing rubber particles to modify asphalt can not only improve asphalt performance, but also help the recycling of waste materials. Considering the effect of different preparation process parameters on the performance of rubber modified asphalt, this paper analyzes the effects of the shear temperature, shear time and shear rate on the performance of rubber modified asphalt, and provided a reference for its preparation.

Virtual-reality-based system for controlled study of cataplexy

NASA Astrophysics Data System (ADS)

Augustine, Kurt E.; Cameron, Bruce M.; Camp, Jon J.; Krahn, Lois E.; Robb, Richard A.

2002-05-01

Cataplexy is a sudden loss of voluntary muscle control experienced by narcolepsy patients. It is usually triggered by strong, spontaneous emotions and is more common in times of stress. The Sleep Disorders Unit and the Biomedical Imaging Resource at Mayo Clinic are developing interactive display technology for reliably inducing cataplexy during clinical monitoring. The project is referred to as the Cataplexy/Narcolepsy Activation Program, or CatNAP. We have developed an automobile driving simulation that introduces humorous, surprising, and stress-inducing events and objects as the patient attempts to navigate a vehicle through a virtual town. The patient wears a head-mounted display and controls the vehicle via a driving simulator steering wheel and pedal cluster. As the patient attempts to drive through the town, various objects, sounds or conditions occur that distract, startle, frustrate or amuse. These responses may trigger a cataplectic episode, which can then be clinically evaluated. We believe CatNAP is a novel and innovative example of the effective application of virtual reality technology to study an important clinical problem that has resisted previous approaches. An evaluation phase with volunteer patients previously diagnosed with cataplexy has been completed. The prototype system is being prepared for a full clinical study.

Facilitating a teleconference-delivered fatigue management program: perspectives of occupational therapists.

PubMed

Dunleavy, Leah; Preissner, Katharine L; Finlayson, Marcia L

2013-12-01

Telehealth refers to the provision of health information and services across a geographical distance. Little is known about the experiences of occupational therapists using this method of service delivery. The study explored the process of facilitating a telehealth intervention from the perspective of occupational therapists. Occupational therapists completed SOAP (Subjective, Objective, Assessment, and Plan) notes after facilitating group-based, teleconference-delivered fatigue management groups to people with multiple sclerosis. Notes were also documented after therapist team meetings. All SOAP notes and field notes were subjected to thematic analysis. Five major themes were identified. "Managing time" was the central theme and was facilitated by professional foundation and challenged by logistics. Managing time contributed to challenging work, which led to the realization that it can work! Based on study findings, the theory and research on clinical reasoning, professional development, and adult learning are relevant to developing curricula that prepare occupational therapists for using telehealth approaches in practice.

Motion simulator study of longitudinal stability requirements for large delta wing transport airplanes during approach and landing with stability augmentation systems failed

NASA Technical Reports Server (NTRS)

Snyder, C. T.; Fry, E. B.; Drinkwater, F. J., III; Forrest, R. D.; Scott, B. C.; Benefield, T. D.

1972-01-01

A ground-based simulator investigation was conducted in preparation for and correlation with an-flight simulator program. The objective of these studies was to define minimum acceptable levels of static longitudinal stability for landing approach following stability augmentation systems failures. The airworthiness authorities are presently attempting to establish the requirements for civil transports with only the backup flight control system operating. Using a baseline configuration representative of a large delta wing transport, 20 different configurations, many representing negative static margins, were assessed by three research test pilots in 33 hours of piloted operation. Verification of the baseline model to be used in the TIFS experiment was provided by computed and piloted comparisons with a well-validated reference airplane simulation. Pilot comments and ratings are included, as well as preliminary tracking performance and workload data.

Quantification of brain lipids by FTIR spectroscopy and partial least squares regression

NASA Astrophysics Data System (ADS)

Dreissig, Isabell; Machill, Susanne; Salzer, Reiner; Krafft, Christoph

2009-01-01

Brain tissue is characterized by high lipid content. Its content decreases and the lipid composition changes during transformation from normal brain tissue to tumors. Therefore, the analysis of brain lipids might complement the existing diagnostic tools to determine the tumor type and tumor grade. Objective of this work is to extract lipids from gray matter and white matter of porcine brain tissue, record infrared (IR) spectra of these extracts and develop a quantification model for the main lipids based on partial least squares (PLS) regression. IR spectra of the pure lipids cholesterol, cholesterol ester, phosphatidic acid, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, sphingomyelin, galactocerebroside and sulfatide were used as references. Two lipid mixtures were prepared for training and validation of the quantification model. The composition of lipid extracts that were predicted by the PLS regression of IR spectra was compared with lipid quantification by thin layer chromatography.

Identification and description of low-molecular weight chemicals inducing hypersensitivity in man

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mari, A.; Misiti, D.; Dorello-Misiti, P.

1988-10-01

The purpose of this study is to compose a list of allergenic chemicals. Each chemical is described in a monograph. The objective of such a monograph program is to collect from the international scientific literature available relevant experimental, chemical, and epidemiological data on chemicals to which humans are known to be exposed and sensitized. A list of 721 chemicals, with related synonyms and trade names, that induce allergic responses and hypersensitivities was prepared. The chemicals were selected on the basis of evidence of human exposure and sensitization. Each monograph contains several data considered relevant to the evaluation of the sensitizingmore » hazards of chemical substances. The data are divided in three sections: chemical identity, sensitizing power, and occurrence. All the data contained in the monographs along with the references and the synonyms are stored in a database application computer program. Preliminary results of 308 of 721 monographs analyzed are reported.« less

Updates to the Generation of Physics Data Inputs for MAMMOTH Simulations of the Transient Reactor Test Facility - FY2016

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ortensi, Javier; Baker, Benjamin Allen; Schunert, Sebastian

The INL is currently evolving the modeling and simulation (M&S) capability that will enable improved core operation as well as design and analysis of TREAT experiments. This M&S capability primarily uses MAMMOTH, a reactor physics application being developed under Multi-physics Object Oriented Simulation Environment (MOOSE) framework. MAMMOTH allows the coupling of a number of other MOOSE-based applications. This second year of work has been devoted to the generation of a deterministic reference solution for the full core, the preparation of anisotropic diffusion coefficients, the testing of the SPH equivalence method, and the improvement of the control rod modeling. In addition,more » this report includes the progress made in the modeling of the M8 core configuration and experiment vehicle since January of this year.« less

Capital Support: Objectives, Policy, Implementation. Brief to the Council of Ontario Universities Prepared by Committee on Capital Financing.

ERIC Educational Resources Information Center

Council of Ontario Universities, Toronto.

To encourage an explicit and more complete statement of policy and objectives so that the universities would have improved opportunities to plan intelligently for the future, the Council of Ontario Universities (COU) prepared this brief to suggest to the Ontario Council on University Affairs (OCUA) some factors to be taken into account in…

Automatic frame-centered object representation and integration revealed by iconic memory, visual priming, and backward masking.

PubMed

Lin, Zhicheng; He, Sheng

2012-10-25

Object identities ("what") and their spatial locations ("where") are processed in distinct pathways in the visual system, raising the question of how the what and where information is integrated. Because of object motions and eye movements, the retina-based representations are unstable, necessitating nonretinotopic representation and integration. A potential mechanism is to code and update objects according to their reference frames (i.e., frame-centered representation and integration). To isolate frame-centered processes, in a frame-to-frame apparent motion configuration, we (a) presented two preceding or trailing objects on the same frame, equidistant from the target on the other frame, to control for object-based (frame-based) effect and space-based effect, and (b) manipulated the target's relative location within its frame to probe frame-centered effect. We show that iconic memory, visual priming, and backward masking depend on objects' relative frame locations, orthogonal of the retinotopic coordinate. These findings not only reveal that iconic memory, visual priming, and backward masking can be nonretinotopic but also demonstrate that these processes are automatically constrained by contextual frames through a frame-centered mechanism. Thus, object representation is robustly and automatically coupled to its reference frame and continuously being updated through a frame-centered, location-specific mechanism. These findings lead to an object cabinet framework, in which objects ("files") within the reference frame ("cabinet") are orderly coded relative to the frame.

Learning from other people’s fear: amygdala-based social reference learning in social anxiety disorder

PubMed Central

Blair, K. S.; Otero, M.; Teng, C.; Geraci, M.; Lewis, E.; Hollon, N.; Blair, R. J. R.; Ernst, Monique; Grillon, C.; Pine, D. S.

2016-01-01

Background Social anxiety disorder involves fear of social objects or situations. Social referencing may play an important role in the acquisition of this fear and could be a key determinant in future biomarkers and treatment pathways. However, the neural underpinnings mediating such learning in social anxiety are unknown. Using event-related functional magnetic resonance imaging, we examined social reference learning in social anxiety disorder. Specifically, would patients with the disorder show increased amygdala activity during social reference learning, and further, following social reference learning, show particularly increased response to objects associated with other people’s negative reactions? Method A total of 32 unmedicated patients with social anxiety disorder and 22 age-, intelligence quotient- and gender-matched healthy individuals responded to objects that had become associated with others’ fearful, angry, happy or neutral reactions. Results During the social reference learning phase, a significant group × social context interaction revealed that, relative to the comparison group, the social anxiety group showed a significantly greater response in the amygdala, as well as rostral, dorsomedial and lateral frontal and parietal cortices during the social, relative to non-social, referencing trials. In addition, during the object test phase, relative to the comparison group, the social anxiety group showed increased bilateral amygdala activation to objects associated with others’ fearful reactions, and a trend towards decreased amygdala activation to objects associated with others’ happy and neutral reactions. Conclusions These results suggest perturbed observational learning in social anxiety disorder. In addition, they further implicate the amygdala and dorsomedial prefrontal cortex in the disorder, and underscore their importance in future biomarker developments. PMID:27476529

A novel no-reference objective stereoscopic video quality assessment method based on visual saliency analysis

NASA Astrophysics Data System (ADS)

Yang, Xinyan; Zhao, Wei; Ye, Long; Zhang, Qin

2017-07-01

This paper proposes a no-reference objective stereoscopic video quality assessment method with the motivation that making the effect of objective experiments close to that of subjective way. We believe that the image regions with different visual salient degree should not have the same weights when designing an assessment metric. Therefore, we firstly use GBVS algorithm to each frame pairs and separate both the left and right viewing images into the regions with strong, general and week saliency. Besides, local feature information like blockiness, zero-crossing and depth are extracted and combined with a mathematical model to calculate a quality assessment score. Regions with different salient degree are assigned with different weights in the mathematical model. Experiment results demonstrate the superiority of our method compared with the existed state-of-the-art no-reference objective Stereoscopic video quality assessment methods.

Establishment of the Ph. Eur. erythropoietin chemical reference substance batch 1.

PubMed

Burns, C; Bristow, A F; Buchheit, K H; Daas, A; Wierer, M; Costanzo, A

2015-01-01

The Erythropoietin (EPO) European Pharmacopoeia (Ph. Eur.) Biological Reference Preparation (BRP) batch 3 was calibrated in 2006 by in vivo bioassay and was used as a reference preparation for these assays as well as for the physicochemical methods in the Ph. Eur. monograph Erythropoietin concentrated solution (1316). In order to avoid the frequent replacement of this standard and thus reduce the use of animals, a new EPO Chemical Reference Substance (CRS) was established to be used solely for the physicochemical methods. Here we report the outcome of a collaborative study aimed at demonstrating the suitability of the candidate CRS (cCRS) as a reference for the physicochemical methods in the Ph. Eur. monograph. Results from the study demonstrated that for the physicochemical methods currently required in the monograph (capillary zone electrophoresis (CZE), polyacrylamide gel electrophoresis (PAGE)/immunoblotting and peptide mapping), the cCRS is essentially identical to the existing BRP. However, data also indicated that, for the physicochemical methods under consideration for inclusion in a revised monograph (test for oxidised forms and glycan mapping), the suitability of the cCRS as a reference needs to be confirmed with additional work. Further to completion of the study, the Ph. Eur. Commission adopted the cCRS as "Erythropoietin for physicochemical tests CRS batch 1" to be used for CZE, PAGE/immunoblotting and peptide mapping.

A new graphite preparation line for AMS 14C dating in the Zagreb Radiocarbon Laboratory

NASA Astrophysics Data System (ADS)

Krajcar Bronić, I.; Horvatinčić, N.; Sironić, A.; Obelić, B.; Barešić, J.; Felja, I.

2010-04-01

The new line for preparation of graphite samples for 14C dating by AMS has been constructed in the Zagreb Radiocarbon Laboratory. The performance of the rig and sample preparation procedure has been validated by preparing graphites from various reference materials of known 14C activity. The yield of the graphitization was good and the measured fraction of modern carbon ( Fm) values have not significantly deviated from the expected ones. Detailed analysis of measured Fm values indicates a slight bias to more positive values and should be carefully investigated.

Antioxidative properties of milk protein preparations fermented by Polish strains of Lactobacillus helveticus.

PubMed

Skrzypczak, Katarzyna W; Gustaw, Waldemar Z; Jabłońska-Ryś, Ewa D; Michalak-Majewska, Monika; Sławińska, Aneta; Radzki, Wojciech P; Gustaw, Klaudia M; Waśko, Adam D

2017-01-01

The increasing significance of food products containing substances with antioxidative activi- ties is currently being observed. This is mainly due to the fact that pathogenic changes underlying some diseases are related to the carcinogenic effects of free radicals. Antioxidative compounds play an important role in supporting and enhancing the body’s defense mechanisms, which is useful in preventing some civili- zation diseases. Unfortunately, it has been already proved that some synthetic antioxidants pose a potential risk in vivo. Therefore, antioxidant compounds derived from a natural source are extremely valuable. Milk is a source of biologically active precursors, which when enclosed in structural protein sequences are inactive. The hydrolysis process, involving bacterial proteolytic enzymes, might release biopeptides that act in various ways, including having antioxidant properties. The objective of this study was to determine the antioxidant properties of milk protein preparations fermented by Polish strains of L. helveticus. The research also focused on evaluating the dynamics of milk acidification by these strains and analyzing the textural properties of the skim milk fermented products obtained. The research studied Polish strains of L. helveticus: B734, 141, T80 and T105, which have not yet been used industrially. The antioxidant properties of 1% (w/v) solutions of milk protein preparations (skim milk powder, caseinoglycomacropeptide and α-lactoalbumin) fermented by these strains were determined by neutralizing the free radicals with 2,2-diphenyl-1-picrylhydrazyl (DPPH˙). Moreover, solutions of skim milk powder (SMP) fermented by the microorganisms being tested were analyzed on gel electrophoresis (SDS-PAGE). The dynamics of milk acidification by these microorganisms was also analyzed L. helveticus strains were used to prepare fermented regenerated skim milk products that were subjected to texture profile analysis (TPA) performed using a TA-XT2i (Stable Micro Systems, Godalming, UK). The results suggest that the antioxidant activity of fermented milk protein preparations depended on the type of milk protein preparation and was also related to the strain that conducted the fermentation process. The process of caseinoglycomacropeptide (CGMP) fermentation by DSMZ 20075, T105 and 141 signifi- cantly (p < 0.05) influenced the increase in the antioxidant activities of the protein preparation, the highest values of parameter were obtained in samples fermented by L. helveticus T105 (64.82 ±0.013%), while in the case of α-lactoalbumin (α-la), the strongest free radical scavenging activity (66.67 ±0.020%) was noted for unfermented samples (control). The greatest increase in DPPH scavenging activity (% of inhibition) was noted for fermented SMP solutions. The highest values of the parameter measured were recorded for SMP fermented by the reference strain (85.98 ±0.009%) and T80 (81.66 ±0.013%). Strain T105 demonstrated the most desirable properties with respect to milk acidifying dynamic and texture properties of fermented skim milk products, while the reference strain (L. helveticus DSMZ 20075) and L. helveticus T80 seem to be more desirable in terms of the possibility of obtaining fermented protein preparations with the best antioxidant properties. The Polish strains analyzed here might find application in dairy products and also in developing functional food products. Furthermore, the preparations of milk protein that were fermented by the strains being tested may be a natural source dietary antioxidants.

Five-Year-Olds Can Show the Self-Reference Advantage

ERIC Educational Resources Information Center

Sui, Jie; Zhu, Ying

2005-01-01

The current study developed a new paradigm to determine the age at which children begin to show the self-reference advantage in memory. Four-, 5-, and 10-year-olds studied lists of colourful object pictures presented together with self or other face image, and participants were asked to report aloud "who is pointing at the (object)."…

User Satisfaction and Service Transactions for a Reference Department in an Illinois Community College Learning Resources Center.

ERIC Educational Resources Information Center

Cornish, Nancy M.

Users of the reference library at Blackhawk Community College (Illinois) were surveyed to determine user satisfaction and the total number of transactions. The survey's objective was to pinpoint problem areas, supply objective information, develop guidelines and standards, and support needed improvements or the continued maintenance of good…

The Role of Inhibition in Moving beyond Perceptually Focused Noun Extensions

ERIC Educational Resources Information Center

Snape, Simon; Krott, Andrea

2018-01-01

When young children interpret novel nouns, they tend to be very much affected by the perceptual features of the referent objects, especially shape. This article investigates whether children might inhibit a prepotent tendency to base novel nouns on the shape of referent objects in order to base them on conceptual features (i.e. taxonomic object…

A Neural Network Architecture For Rapid Model Indexing In Computer Vision Systems

NASA Astrophysics Data System (ADS)

Pawlicki, Ted

1988-03-01

Models of objects stored in memory have been shown to be useful for guiding the processing of computer vision systems. A major consideration in such systems, however, is how stored models are initially accessed and indexed by the system. As the number of stored models increases, the time required to search memory for the correct model becomes high. Parallel distributed, connectionist, neural networks' have been shown to have appealing content addressable memory properties. This paper discusses an architecture for efficient storage and reference of model memories stored as stable patterns of activity in a parallel, distributed, connectionist, neural network. The emergent properties of content addressability and resistance to noise are exploited to perform indexing of the appropriate object centered model from image centered primitives. The system consists of three network modules each of which represent information relative to a different frame of reference. The model memory network is a large state space vector where fields in the vector correspond to ordered component objects and relative, object based spatial relationships between the component objects. The component assertion network represents evidence about the existence of object primitives in the input image. It establishes local frames of reference for object primitives relative to the image based frame of reference. The spatial relationship constraint network is an intermediate representation which enables the association between the object based and the image based frames of reference. This intermediate level represents information about possible object orderings and establishes relative spatial relationships from the image based information in the component assertion network below. It is also constrained by the lawful object orderings in the model memory network above. The system design is consistent with current psychological theories of recognition by component. It also seems to support Marr's notions of hierarchical indexing. (i.e. the specificity, adjunct, and parent indices) It supports the notion that multiple canonical views of an object may have to be stored in memory to enable its efficient identification. The use of variable fields in the state space vectors appears to keep the number of required nodes in the network down to a tractable number while imposing a semantic value on different areas of the state space. This semantic imposition supports an interface between the analogical aspects of neural networks and the propositional paradigms of symbolic processing.

Lexical Entrainment and Lexical Differentiation in Reference Phrase Choice

ERIC Educational Resources Information Center

Van Der Wege, Mija M.

2009-01-01

Speakers reuse prior references to objects when choosing reference phrases, a phenomenon known as lexical entrainment. One explanation is that speakers want to maintain a set of previously established referential precedents. Speakers may also contrast any new referents against this previously established set, thereby avoiding applying the same…

Bacterial Contamination of Hands Increases Risk of Cross-Contamination among Low-Income Puerto Rican Meal Preparers

ERIC Educational Resources Information Center

Dharod, Jigna Morarji; Paciello, Stefania; Bermudez-Millan, Angela; Venkitanarayanan, Kumar; Damio, Grace; Perez-Escamilla, Rafael

2009-01-01

Objective: To examine the association of microbial contamination of the meal preparer's hands with microbial status of food and kitchen/utensil surfaces during home preparation of a "Chicken and Salad" meal. Design and Setting: Observational home food safety assessment. Before starting meal preparation, participants' hands were tested to…

Annual Stock Assessment - CWT [Coded Wire Tag program] (USFWS), Annual Report 2007.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pastor, Stephen M.

2009-07-21

In 1989 the Bonneville Power Administration (BPA) began funding the evaluation of production groups of juvenile anadromous fish not being coded-wire tagged for other programs. These groups were the 'Missing Production Groups'. Production fish released by the U.S. Fish and Wildlife Service (FWS) without representative coded-wire tags during the 1980s are indicated as blank spaces on the survival graphs in this report. This program is now referred to as 'Annual Stock Assessment - CWT'. The objectives of the 'Annual Stock Assessment' program are to: (1) estimate the total survival of each production group, (2) estimate the contribution of each productionmore » group to fisheries, and (3) prepare an annual report for USFWS hatcheries in the Columbia River basin. Coded-wire tag recovery information will be used to evaluate the relative success of individual brood stocks. This information can also be used by salmon harvest managers to develop plans to allow the harvest of excess hatchery fish while protecting threatened, endangered, or other stocks of concern. All fish release information, including marked/unmarked ratios, is reported to the Pacific States Marine Fisheries Commission (PSMFC). Fish recovered in the various fisheries or at the hatcheries are sampled to recover coded-wire tags. This recovery information is also reported to PSMFC. This report has been prepared annually starting with the report labeled 'Annual Report 1994'. Although the current report has the title 'Annual Report 2007', it was written in fall of 2008 using data available from RMIS that same year, and submitted as final in January 2009. The main objective of the report is to evaluate survival of groups which have been tagged under this ongoing project.« less

76 FR 31359 - Notice of Intent To Prepare an Environmental Impact Statement on a General Management Plan...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-31

... approaches and the possible designation of wilderness within the park. All interested persons, organizations... DEPARTMENT OF THE INTERIOR National Park Service [9921-9855-409] Notice of Intent To Prepare an... (referred to hereafter as the park), setting broad management goals for managing the area during the next 15...

Non-traditional Oxidants in Preparative Coordination Chemistry

NASA Astrophysics Data System (ADS)

Kukushkin, Vadim Yu; Kukushkin, Yurii N.

1986-10-01

The application of nitrosonium and arenediazonium salts, carbenium, silver(I), and mercury(II) ions, protic acids, and amine oxides as oxidants in preparative coordination chemistry is examined. Specific examples illustrate which problems in the field of the synthesis and reactions of coordination compounds can be solved with the aid of these oxidants. The bibliography includes 158 references.

Vapor Pressure and Predicted Stability of American Contact Dermatitis Society Core Allergens

PubMed Central

Jou, Paul C.; Siegel, Paul D.; Warshaw, Erin M.

2018-01-01

Background Accurate patch testing is reliant on proper preparation of patch test allergens. The stability of patch test allergens is dependent on several factors including vapor pressure (VP). Objective This investigation reviews the VP of American Contact Dermatitis Society Core Allergens and compares stability predictions based on VP with those established through clinical testing. Methods Standard references were accessed for determining VP in millimeters of mercury and associated temperature in degrees celsius. If multiple values were listed, VP at temperatures that most approximate indoor storage conditions (20°C and 25°C) were chosen. For mixes, the individual component with the highest VP was chosen as the overall VP, assuming that the most volatile substance would evaporate first. Antigens were grouped into low (≤0.001 mm Hg), moderate (<1 to >0.001 mm Hg), and high (≥1 mm Hg) volatility using arbitrary cutoff values. Conclusions This review is consistent with previously reported data on formaldehyde, acrylates, and fragrance material instability. Given lack of testing data, VP can be useful in predicting patch test compound stability. Measures such as air-tight multidose reagent containers, sealed single-application dispensers, preparation of patches immediately before application, and storage at lower temperatures may remedy some of these issues. PMID:27427821

Dependence for food-related activities in the elderly.

PubMed

Bierhals, Isabel Oliveira; Meller, Fernanda de Oliveira; Assunção, Maria Cecília Formoso

2016-04-01

The objective of this study was to describe dependence for the activities of food shopping, preparing meals and eating in elderly residents from the city of Pelotas, Rio Grande do Sul. Bivariate analysis and ordinal logistic regression were employed to assess the three dependencies and exposure variables studied. Of the 1,451 older adults assessed, 21.1% required assistance for some activities where this care was given predominantly by son/daughter and partners. The highest prevalence of dependence was for food shopping (20.7%), followed by preparing meals (11.5%) and eating (2.0%). Elderly aged 80 years or older were more likely to be in a greater dependence category than individuals aged 60-69 years, with odds ratios of 5.0 for men and 7.1 for women. The odds ratio in individuals who self-rated their health as regular, poor or very poor was approximately 2.3 times greater, proving similar for both genders. Women with no partner had a 1.7 times greater chance of dependence whilst individuals with greater educational level exhibited 70.0% protection for their reference category; men with lower socioeconomic level had a 5.3 times greater chance of dependence than individuals with higher socioeconomic level. These results highlight the most vulnerable subgroups for dependencies and the importance of a family caregiver.

Decommissioning Handbook

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-03-01

The Decommissioning Handbook is a technical guide for the decommissioning of nuclear facilities. The decommissioning of a nuclear facility involves the removal of the radioactive and, for practical reasons, hazardous materials to enable the facility to be released and not represent a further risk to human health and the environment. This handbook identifies and technologies and techniques that will accomplish these objectives. The emphasis in this handbook is on characterization; waste treatment; decontamination; dismantling, segmenting, demolition; and remote technologies. Other aspects that are discussed in some detail include the regulations governing decommissioning, worker and environmental protection, and packaging and transportationmore » of the waste materials. The handbook describes in general terms the overall decommissioning project, including planning, cost estimating, and operating practices that would ease preparation of the Decommissioning Plan and the decommissioning itself. The reader is referred to other documents for more detailed information. This Decommissioning Handbook has been prepared by Enserch Environmental Corporation for the US Department of Energy and is a complete restructuring of the original handbook developed in 1980 by Nuclear Energy Services. The significant changes between the two documents are the addition of current and the deletion of obsolete technologies and the addition of chapters on project planning and the Decommissioning Plan, regulatory requirements, characterization, remote technology, and packaging and transportation of the waste materials.« less

Development of the Quality Assurance/Quality Control Procedures for a Neutron Interrogation System

NASA Astrophysics Data System (ADS)

Obhođaš, Jasmina; Sudac, Davorin; Valković, Vladivoj

2016-06-01

In order to perform Quality Assurance/Quality Control (QA/QC) procedures for a system dedicated to the neutron interrogation of objects for the presence of threat materials one needs to perform measurements of reference materials (RM) i.e. simulants having the same (or similar) atomic ratios as real materials. It is well known that explosives, drugs, and various other benign materials, contain chemical elements such as hydrogen, oxygen, carbon and nitrogen in distinctly different quantities. For example, a high carbon-to-oxygen ratio (C/O) is characteristic of drugs. Explosives can be differentiated by measurement of both (C/O) and nitrogen-to-oxygen (N/O) ratios. The C/N ratio of the chemical warfare agents, coupled with the measurement of elements such as fluorine and phosphorus, clearly differentiate them from the conventional explosives. Here we present the RM preparation, calibration procedure and correlations attained between theoretical values and experimentally obtained results in laboratory conditions for C/O and N/C ratios of prepared hexogen (RDX), TNT, DLM2, TATP, cocaine, heroin, yperite, tetranitromethane, peroxide methylethylketone, nitromethane and ethyleneglycol dinitrate simulants. We have shown that analyses of the gamma ray spectra by using simple unfolding model developed for this purpose gave a nice agreement with the chemical formula of created simulants, thus the calibration quality was successfully tested.

Fiber Concentrate from Orange (Citrus sinensis L.) Bagase: Characterization and Application as Bakery Product Ingredient

PubMed Central

Romero-Lopez, Maria R.; Osorio-Diaz, Perla; Bello-Perez, Luis A.; Tovar, Juscelino; Bernardino-Nicanor, Aurea

2011-01-01

Orange is a tropical fruit used in the juice industry, yielding important quantities of by products. The objective of this work was to obtain a dietary fiber-rich orange bagasse product (DFROBP), evaluate its chemical composition and its use in the preparation of a bakery product (muffin). Muffins containing two different levels of DFROBP were studied regarding chemical composition, in vitro starch digestibility, predicted glyceamic index and acceptability in a sensory test. DFROBP showed low fat and high dietary fiber contents. The soluble and insoluble dietary fiber fractions were balanced, which is of importance for the health beneficial effects of fiber sources. DFROBP-containing muffins showed the same rapidly digestible starch content as the reference muffin, whilst the slowly digestible starch level increased with the addition of DFROBP. However, the resistant starch content decreased when DFROBP increased in the muffin. The addition of DFROBP to muffin decreased the predicted glyceamic index, but no difference was found between the muffins prepared with the two DFROBP levels. The sensory score did not show difference between control muffin and that added with 10% of DFROBP. The addition of DFROBP to bakery products can be an alternative for people requiring low glyceamic response. PMID:21731434

Preparation of reference material for UGT1A1 (TA)n polymorphism genotyping.

PubMed

Mlakar, Vid; Mlakar, Simona Jurković; Marc, Janja; Ostanek, Barbara

2014-08-05

Gilbert's syndrome is one of the most common metabolic syndromes in the human population characterised by mild unconjugated hyperbilirubinemia resulting from reduced activity of the bilirubin conjugating enzyme UDP-glucuronosyltransferase (UGT1A1). Although Gilbert's syndrome is usually quite benign UGT1A1(TA)n genotyping is important in exclusion of more serious causes of hyperbilirubinemia and since it has significant implications for personalised medicine. The aim of our study was to develop plasmid based reference materials which could be used for UGT1A1(TA)n genotyping. Plasmids were generated using recombinant DNA technology and their number of repeats as well as the entire sequence verified by Sanger sequencing. Their suitability as reference materials was tested using sizing by capillary electrophoresis and denaturing high performance liquid chromatography. Plasmids containing all four different alleles (TA)5, (TA)6, (TA)7 and (TA)8 that are present in the human population as well as a plasmid with (TA)4 repeats were successfully generated. Prepared plasmid reference materials allow the creation of all possible UGT1A1(TA)n polymorphism genotypes and can serve as an efficient substitute for the human genomic DNA reference material in routine genotyping and in the development of new genotyping tests. Copyright © 2014 Elsevier B.V. All rights reserved.

Oxygen potential of uranium--plutonium oxide as determined by controlled- atmosphere thermogravimetry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Swanson, Gerald C.

1975-10-01

The oxygen-to-metal atom ratio, or O/M, of solid solution uranium- plutonium oxide reactor fuel is a measure of the concentration of crystal defects in the oxide which affect many fuel properties, particularly, fuel oxygen potential. Fabrication of a high-temperature oxygen electrode, employing an electro-active tip of oxygen-deficient solid-state electrolyte, intended to confirm gaseous oxygen potentials is described. Uranium oxide and plutonium oxide O/M reference materials were prepared by in situ oxidation of high purity metals in the thermobalance. A solid solution uranium-plutonium oxide O/M reference material was prepared by alloying the uranium and plutonium metals in a yttrium oxide cruciblemore » at 1200°C and oxidizing with moist He at 250°C. The individual and solid solution oxides were isothermally equilibrated with controlled oxygen potentials between 800 and 1300°C and the equilibrated O/ M ratios calculated with corrections for impurities and buoyancy effects. Use of a reference oxygen potential of -100 kcal/mol to produce an O/M of 2.000 is confirmed by these results. However, because of the lengthy equilibration times required for all oxides, use of the O/M reference materials rather than a reference oxygen potential is recommended for O/M analysis methods calibrations.« less

NASCAP programmer's reference manual

NASA Astrophysics Data System (ADS)

Mandell, M. J.; Stannard, P. R.; Katz, I.

1993-05-01

The NASA Charging Analyzer Program (NASCAP) is a computer program designed to model the electrostatic charging of complicated three-dimensional objects, both in a test tank and at geosynchronous altitudes. This document is a programmer's reference manual and user's guide. It is designed as a reference to experienced users of the code, as well as an introduction to its use for beginners. All of the many capabilities of NASCAP are covered in detail, together with examples of their use. These include the definition of objects, plasma environments, potential calculations, particle emission and detection simulations, and charging analysis.

NASCAP programmer's reference manual

NASA Technical Reports Server (NTRS)

Mandell, M. J.; Stannard, P. R.; Katz, I.

1993-01-01

The NASA Charging Analyzer Program (NASCAP) is a computer program designed to model the electrostatic charging of complicated three-dimensional objects, both in a test tank and at geosynchronous altitudes. This document is a programmer's reference manual and user's guide. It is designed as a reference to experienced users of the code, as well as an introduction to its use for beginners. All of the many capabilities of NASCAP are covered in detail, together with examples of their use. These include the definition of objects, plasma environments, potential calculations, particle emission and detection simulations, and charging analysis.

[Phosphoric acid ester preparations used in cattle, swine and sheep with special reference to cholinesterase activity. 4. Use of phosphoric acid esters and their effect on acetylcholinesterase activity in sheep].

PubMed

Mieth, K; Beier, D; Losch, K

1975-01-01

The use of organophosphorus preparations for the control of ectoparasites and endoparasites of sheep, particularly systemic application, is discussed. Experiments on 13 groups of sheep with five preparations produced in the German Democratic Republic in various formulations and concentrations showed that external application had good contact activity, but little was absorbed. Acetylcholinesterase activity was not inhibited, except by pour-on application of doses several times the normal dose. The preparations were arranged in order of cholinesterase inhibition. In contrast to cattle, diminished cholinesterase activity was unreliable as in indicator of systemic toxicity of organophosphorus preparations in sheep.

Audiovisual alignment of co-speech gestures to speech supports word learning in 2-year-olds.

PubMed

Jesse, Alexandra; Johnson, Elizabeth K

2016-05-01

Analyses of caregiver-child communication suggest that an adult tends to highlight objects in a child's visual scene by moving them in a manner that is temporally aligned with the adult's speech productions. Here, we used the looking-while-listening paradigm to examine whether 25-month-olds use audiovisual temporal alignment to disambiguate and learn novel word-referent mappings in a difficult word-learning task. Videos of two equally interesting and animated novel objects were simultaneously presented to children, but the movement of only one of the objects was aligned with an accompanying object-labeling audio track. No social cues (e.g., pointing, eye gaze, touch) were available to the children because the speaker was edited out of the videos. Immediately afterward, toddlers were presented with still images of the two objects and asked to look at one or the other. Toddlers looked reliably longer to the labeled object, demonstrating their acquisition of the novel word-referent mapping. A control condition showed that children's performance was not solely due to the single unambiguous labeling that had occurred at experiment onset. We conclude that the temporal link between a speaker's utterances and the motion they imposed on the referent object helps toddlers to deduce a speaker's intended reference in a difficult word-learning scenario. In combination with our previous work, these findings suggest that intersensory redundancy is a source of information used by language users of all ages. That is, intersensory redundancy is not just a word-learning tool used by young infants. Copyright © 2015 Elsevier Inc. All rights reserved.

Spent Nuclear Fuel (SNF) Project Canister Storage Building (CSB) Process Flow Diagram Mass Balance Calculations

DOE Office of Scientific and Technical Information (OSTI.GOV)

KLEM, M.J.

2000-05-11

The purpose of these calculations is to develop the material balances for documentation of the Canister Storage Building (CSB) Process Flow Diagram (PFD) and future reference. The attached mass balances were prepared to support revision two of the PFD for the CSB. The calculations refer to diagram H-2-825869.

Assessing distribution and movement of blue catfish in Kansas reservoirs

USGS Publications Warehouse

Mather, Martha E.; Gerber, Kayla M.; Peterson, Zachary

2015-01-01

This report is organized into three chapters that address six objectives. The first chapter addresses objectives 1-3. The second chapter addresses objectives 4-5. The third chapter addresses objective 6. The objectives for the project are listed below for reference.

Motion compensation and noise tolerance in phase-shifting digital in-line holography.

PubMed

Stenner, Michael D; Neifeld, Mark A

2006-05-15

We present a technique for phase-shifting digital in-line holography which compensates for lateral object motion. By collecting two frames of interference between object and reference fields with identical reference phase, one can estimate the lateral motion that occurred between frames using the cross-correlation. We also describe a very general linear framework for phase-shifting holographic reconstruction which minimizes additive white Gaussian noise (AWGN) for an arbitrary set of reference field amplitudes and phases. We analyze the technique's sensitivity to noise (AWGN, quantization, and shot), errors in the reference fields, errors in motion estimation, resolution, and depth of field. We also present experimental motion-compensated images achieving the expected resolution.

Discriminating ultrasonic proximity detection system

DOEpatents

Annala, Wayne C.

1989-01-01

This invention uses an ultrasonic transmitter and receiver and a microprocessor to detect the presence of an object. In the reset mode the invention uses a plurality of echoes from each ultrasonic burst to create a reference table of the echo-burst-signature of the empty monitored environment. The invention then processes the reference table so that it only uses the most reliable data. In the detection mode the invention compares the echo-burst-signature of the present environment with the reference table, detecting an object if there is a consistent difference between the echo-burst-signature of the empty monitored environment recorded in the reference table and the echo-burst-signature of the present environment.

International reference reagents: antihuman globulin. An ISBT/ICSH joint working party report. International Society of Blood Transfusion. International Committee for Standardization in Haematology.

PubMed

Case, J; Ford, D S; Chung, A; Collins, R; Kochman, S; Mazda, T; Overbeeke, M; Perera, R; Sakuldamrongpanich, T; Scott, M; Voak, D; Zupańska, B

1999-01-01

An international working party has conducted a study designed to select a suitable reference reagent for antihuman globulin, to replace those first made available in 1987. The chosen preparation contains levels of anti-IgG and anti-C3 (anti-C3c and anti-C3d) potency that are considered suitable to serve for reference when evaluating either polyspecific antihuman globulin reagents or those containing their separate monospecific components. The reference material is available in 2-ml freeze-dried aliquots from seven assigned distribution centres.

Making intelligent systems team players. A guide to developing intelligent monitoring systems

NASA Technical Reports Server (NTRS)

Land, Sherry A.; Malin, Jane T.; Thronesberry, Carroll; Schreckenghost, Debra L.

1995-01-01

This reference guide for developers of intelligent monitoring systems is based on lessons learned by developers of the DEcision Support SYstem (DESSY), an expert system that monitors Space Shuttle telemetry data in real time. DESSY makes inferences about commands, state transitions, and simple failures. It performs failure detection rather than in-depth failure diagnostics. A listing of rules from DESSY and cue cards from DESSY subsystems are included to give the development community a better understanding of the selected model system. The G-2 programming tool used in developing DESSY provides an object-oriented, rule-based environment, but many of the principles in use here can be applied to any type of monitoring intelligent system. The step-by-step instructions and examples given for each stage of development are in G-2, but can be used with other development tools. This guide first defines the authors' concept of real-time monitoring systems, then tells prospective developers how to determine system requirements, how to build the system through a combined design/development process, and how to solve problems involved in working with real-time data. It explains the relationships among operational prototyping, software evolution, and the user interface. It also explains methods of testing, verification, and validation. It includes suggestions for preparing reference documentation and training users.

UO 2 Particle Standards: Synthesis, Purification & Planchet Preparation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barrett, Christopher A.; Anheier, Norman C.

2016-03-31

The IAEA has previously indicated its desire for reliable provision of suitable reference materials in support of environmental sample analysis and sustained advancement at the Department of Safeguards, as laid out in the Long Term R&D plan (LTRD 10.1 & 10.2). In a recent meeting between NPAC, the IAEA and PNNL, this pressing need was directly outlined by the IAEA as having two main objectives. The first pertains to current operations, such as instrument calibrations and evaluation of bias across the Network of Analytical Laboratories and requires particles on the order of 300-500 nm in diameter. The second need formore » particle reference material would directly support the IAEA’s ongoing R&D efforts and calls for smaller particles ranging from 50 -100 nm in size. As such, the IAEA has expressed a great deal of interest in the newly established synthesis capabilities at PNNL, initially cultivated through a PNNL LDRD project to address the particle-standards shortcomings for uranium oxide material. The joint meeting concluded with a request by the IAEA for 1-2 planchet samples containing PNNL’s UO 2 particulate material, to be delivered in the near-term. This report outlines the steps taken to meet that request and includes some basic characteristics of the samples sent to the IAEA.« less

Fibrinolysis standards: a review of the current status.

PubMed

Thelwell, C

2010-07-01

Biological standards are used to calibrate measurements of components of the fibrinolytic system, either for assigning potency values to therapeutic products, or to determine levels in human plasma as an indicator of thrombotic risk. Traditionally WHO International Standards are calibrated in International Units based on consensus values from collaborative studies. The International Unit is defined by the response activity of a given amount of the standard in a bioassay, independent of the method used. Assay validity is based on the assumption that both standard and test preparation contain the same analyte, and the response in an assay is a true function of this analyte. This principle is reflected in the diversity of source materials used to prepare fibrinolysis standards, which has depended on the contemporary preparations they were employed to measure. With advancing recombinant technology, and improved analytical techniques, a reference system based on reference materials and associated reference methods has been recommended for future fibrinolysis standards. Careful consideration and scientific judgement must however be applied when deciding on an approach to develop a new standard, with decisions based on the suitability of a standard to serve its purpose, and not just to satisfy a metrological ideal. 2010 The International Association for Biologicals. Published by Elsevier Ltd. All rights reserved.

Design Considerations of a Compounded Sterile Preparations Course

PubMed Central

Petraglia, Christine; Mattison, Melissa J.

2016-01-01

Objective. To design a comprehensive learning and assessment environment for the practical application of compounded sterile preparations using a constructivist approach. Design. Compounded Sterile Preparations Laboratory is a required 1-credit course that builds upon the themes of training aseptic technique typically used in health system settings and threads application of concepts from other courses in the curriculum. Students used critical-thinking skills to devise appropriate strategies to compound sterile preparations. Assessment. Aseptic technique skills were assessed with objective, structured, checklist-based rubrics. Most students successfully completed practical assessments using appropriate technique (mean assessment grade=83.2%). Almost all students passed the practical media fill (98%) and gloved fingertip sampling (86%) tests on the first attempt; all passed on the second attempt. Conclusion. Employing a constructivist scaffold approach to teaching proper hygiene and aseptic technique prepared students to pass media fill and gloved fingertip tests and to perform well on practical compounding assessments. PMID:26941438

Irrigation Training Manual. Planning, Design, Operation, and Management of Small-Scale Irrigation Systems [and] Irrigation Reference Manual. A Technical Reference to Be Used with the Peace Corps Irrigation Training Manual T0076 in the Selection, Planning, Design, Operation, and Management of Small-Scale Irrigation Systems.

ERIC Educational Resources Information Center

Salazar, LeRoy; And Others

This resource for trainers involved in irrigated agriculture training for Peace Corps volunteers consists of two parts: irrigation training manual and irrigation reference manual. The complete course should fully prepare volunteers serving as irrigation, specialists to plan, implement, evaluate and manage small-scale irrigation projects in arid,…

Reference Frames and 3-D Shape Perception of Pictured Objects: On Verticality and Viewpoint-From-Above

PubMed Central

van Doorn, Andrea J.; Wagemans, Johan

2016-01-01

Research on the influence of reference frames has generally focused on visual phenomena such as the oblique effect, the subjective visual vertical, the perceptual upright, and ambiguous figures. Another line of research concerns mental rotation studies in which participants had to discriminate between familiar or previously seen 2-D figures or pictures of 3-D objects and their rotated versions. In the present study, we disentangled the influence of the environmental and the viewer-centered reference frame, as classically done, by comparing the performances obtained in various picture and participant orientations. However, this time, the performance is the pictorial relief: the probed 3-D shape percept of the depicted object reconstructed from the local attitude settings of the participant. Comparisons between the pictorial reliefs based on different picture and participant orientations led to two major findings. First, in general, the pictorial reliefs were highly similar if the orientation of the depicted object was vertical with regard to the environmental or the viewer-centered reference frame. Second, a viewpoint-from-above interpretation could almost completely account for the shears occurring between the pictorial reliefs. More specifically, the shears could largely be considered as combinations of slants generated from the viewpoint-from-above, which was determined by the environmental as well as by the viewer-centered reference frame. PMID:27433329

Multiobject relative fuzzy connectedness and its implications in image segmentation

NASA Astrophysics Data System (ADS)

Udupa, Jayaram K.; Saha, Punam K.

2001-07-01

The notion of fuzzy connectedness captures the idea of hanging-togetherness of image elements in an object by assigning a strength of connectedness to every possible path between every possible pair of image elements. This concept leads to powerful image segmentation algorithms based on dynamic programming whose effectiveness has been demonstrated on 1000s of images in a variety of applications. In a previous framework, we introduced the notion of relative fuzzy connectedness for separating a foreground object from a background object. In this framework, an image element c is considered to belong to that among these two objects with respect to whose reference image element c has the higher strength of connectedness. In fuzzy connectedness, a local fuzzy reflation called affinity is used on the image domain. This relation was required for theoretical reasons to be of fixed form in the previous framework. In the present paper, we generalize relative connectedness to multiple objects, allowing all objects (of importance) to compete among themselves to grab membership of image elements based on their relative strength of connectedness to reference elements. We also allow affinity to be tailored to the individual objects. We present a theoretical and algorithmic framework and demonstrate that the objects defined are independent of the reference elements chosen as long as they are not in the fuzzy boundary between objects. Examples from medical imaging are presented to illustrate visually the effectiveness of multiple object relative fuzzy connectedness. A quantitative evaluation based on 160 mathematical phantom images demonstrates objectively the effectiveness of relative fuzzy connectedness with object- tailored affinity relation.

Bilingualism Affects 9-Month-Old Infants' Expectations about How Words Refer to Kinds

ERIC Educational Resources Information Center

Byers-Heinlein, Krista

2017-01-01

Infants are precocious word learners, and seem to possess systematic expectations about how words refer to object kinds. For example, while monolingual infants show a one-to-one mapping bias (e.g. mutual exclusivity), expecting each object to have only one basic level label, previous research has shown that this is less robust in bi- and…

If You Say Thee Uh You Are Describing Something Hard: The On-Line Attribution of Disfluency during Reference Comprehension

ERIC Educational Resources Information Center

Arnold, Jennifer E.; Kam, Carla L. Hudson; Tanenhaus, Michael K.

2007-01-01

Eye-tracking and gating experiments examined reference comprehension with fluent (Click on the red. . .) and disfluent (Click on [pause] thee uh red . . .) instructions while listeners viewed displays with 2 familiar (e.g., ice cream cones) and 2 unfamiliar objects (e.g., squiggly shapes). Disfluent instructions made unfamiliar objects more…

Looking at a contrast object before speaking boosts referential informativeness, but is not essential.

PubMed

Davies, Catherine; Kreysa, Helene

2017-07-01

Variation in referential form has traditionally been accounted for by theoretical frameworks focusing on linguistic and discourse features. Despite the explosion of interest in eye tracking methods in psycholinguistics, the role of visual scanning behaviour in informative reference production is yet to be comprehensively investigated. Here we examine the relationship between speakers' fixations to relevant referents and the form of the referring expressions they produce. Overall, speakers were fully informative across simple and (to a lesser extent) more complex displays, providing appropriately modified referring expressions to enable their addressee to locate the target object. Analysis of contrast fixations revealed that looking at a contrast object boosts but is not essential for full informativeness. Contrast fixations which take place immediately before speaking provide the greatest boost. Informative referring expressions were also associated with later speech onsets than underinformative ones. Based on the finding that fixations during speech planning facilitate but do not fully predict informative referring, direct visual scanning is ruled out as a prerequisite for informativeness. Instead, pragmatic expectations of informativeness may play a more important role. Results are consistent with a goal-based link between eye movements and language processing, here applied for the first time to production processes. Copyright © 2017 Elsevier B.V. All rights reserved.

Sharing reference data and including cows in the reference population improve genomic predictions in Danish Jersey

USDA-ARS?s Scientific Manuscript database

Small reference populations limit the accuracy of genomic prediction in numerically small breeds, such as the Danish Jersey. The objective of this study was to investigate two approaches to improve genomic prediction by increasing the size of the reference population for Danish Jerseys. The first ap...

Automatic frame-centered object representation and integration revealed by iconic memory, visual priming, and backward masking

PubMed Central

Lin, Zhicheng; He, Sheng

2012-01-01

Object identities (“what”) and their spatial locations (“where”) are processed in distinct pathways in the visual system, raising the question of how the what and where information is integrated. Because of object motions and eye movements, the retina-based representations are unstable, necessitating nonretinotopic representation and integration. A potential mechanism is to code and update objects according to their reference frames (i.e., frame-centered representation and integration). To isolate frame-centered processes, in a frame-to-frame apparent motion configuration, we (a) presented two preceding or trailing objects on the same frame, equidistant from the target on the other frame, to control for object-based (frame-based) effect and space-based effect, and (b) manipulated the target's relative location within its frame to probe frame-centered effect. We show that iconic memory, visual priming, and backward masking depend on objects' relative frame locations, orthogonal of the retinotopic coordinate. These findings not only reveal that iconic memory, visual priming, and backward masking can be nonretinotopic but also demonstrate that these processes are automatically constrained by contextual frames through a frame-centered mechanism. Thus, object representation is robustly and automatically coupled to its reference frame and continuously being updated through a frame-centered, location-specific mechanism. These findings lead to an object cabinet framework, in which objects (“files”) within the reference frame (“cabinet”) are orderly coded relative to the frame. PMID:23104817

A Process Manual: Staff Development in American-Sponsored Overseas Schools.

ERIC Educational Resources Information Center

Anderson, Carrel M.; Schaffer, Raymond, Jr.

This manual is written for those responsible for staff development in American-sponsored overseas schools (ASOS). Program management for staff development planning is divided into seven categories: (1) mission statement preparation; (2) needs assessment survey; (3) goal statements preparation; (4) staff objectives preparation; (5) activities…

Endoscopic pulsed digital holography for 3D measurements

NASA Astrophysics Data System (ADS)

Saucedo, A. Tonatiuh; Mendoza Santoyo, Fernando; de La Torre-Ibarra, Manuel; Pedrini, Giancarlo; Osten, Wolfgang

2006-02-01

A rigid endoscope and three different object illumination source positions are used in pulsed digital holography to measure the three orthogonal displacement components from hidden areas of a harmonically vibrating metallic cylinder. In order to obtain simultaneous 3D information from the optical set up, it is necessary to match the optical paths of each of the reference object beam pairs, but to incoherently mismatch the three reference object beam pairs, such that three pulsed digital holograms are incoherently recorded within a single frame of the CCD sensor. The phase difference is obtained using the Fourier method and by subtracting two digital holograms captured for two different object positions.

Tracking of multiple targets using online learning for reference model adaptation.

PubMed

Pernkopf, Franz

2008-12-01

Recently, much work has been done in multiple object tracking on the one hand and on reference model adaptation for a single-object tracker on the other side. In this paper, we do both tracking of multiple objects (faces of people) in a meeting scenario and online learning to incrementally update the models of the tracked objects to account for appearance changes during tracking. Additionally, we automatically initialize and terminate tracking of individual objects based on low-level features, i.e., face color, face size, and object movement. Many methods unlike our approach assume that the target region has been initialized by hand in the first frame. For tracking, a particle filter is incorporated to propagate sample distributions over time. We discuss the close relationship between our implemented tracker based on particle filters and genetic algorithms. Numerous experiments on meeting data demonstrate the capabilities of our tracking approach. Additionally, we provide an empirical verification of the reference model learning during tracking of indoor and outdoor scenes which supports a more robust tracking. Therefore, we report the average of the standard deviation of the trajectories over numerous tracking runs depending on the learning rate.

Laser heterodyne surface profiler

DOEpatents

Sommargren, Gary E.

1982-01-01

A method and apparatus is disclosed for testing the deviation of the face of an object from a flat smooth surface using a beam of coherent light of two plane-polarized components, one of a frequency constantly greater than the other by a fixed amount to produce a difference frequency with a constant phase to be used as a reference. The beam also is split into its two components with the separate components directed onto spaced apart points onthe face of the object to be tested for smoothness. The object is rotated on an axis coincident with one component which is directed to the face of the object at the center which constitutes a virtual fixed point. This component also is used as a reference. The other component follows a circular track on the face of the object as the object is rotated. The two components are recombined after reflection to produce a reflected frequency difference of a phase proportional to the difference in path length which is compared with the reference phase to produce a signal proportional to the deviation of the height of the surface along the circular track with respect to the fixed point at the center.

Inferring difficulty: Flexibility in the real-time processing of disfluency

PubMed Central

Heller, Daphna; Arnold, Jennifer E.; Klein, Natalie M.; Tanenhaus, Michael K.

2015-01-01

Upon hearing a disfluent referring expression, listeners expect the speaker to refer to an object that is previously-unmentioned, an object that does not have a straightforward label, or an object that requires a longer description. Two visual-world eye-tracking experiments examined whether listeners directly associate disfluency with these properties of objects, or whether disfluency attribution is more flexible and involves situation-specific inferences. Since in natural situations reference to objects that do not have a straightforward label or that require a longer description is correlated with both production difficulty and with disfluency, we used a mini artificial lexicon to dissociate difficulty from these properties, building on the fact that recently-learned names take longer to produce than existing words in one’s mental lexicon. The results demonstrate that disfluency attribution involves situation-specific inferences; we propose that in new situations listeners spontaneously infer what may cause production difficulty. However, the results show that these situation-specific inferences are limited in scope: listeners assessed difficulty relative to their own experience with the artificial names, and did not adapt to the assumed knowledge of the speaker. PMID:26677642

Whisking mechanics and active sensing

PubMed Central

Bush, Nicholas E; Solla, Sara A

2017-01-01

We describe recent advances in quantifying the three-dimensional (3D) geometry and mechanics of whisking. Careful delineation of relevant 3D reference frames reveals important geometric and mechanical distinctions between the localization problem (‘where’ is an object) and the feature extraction problem (‘what’ is an object). Head-centered and resting-whisker reference frames lend themselves to quantifying temporal and kinematic cues used for object localization. The whisking-centered reference frame lends itself to quantifying the contact mechanics likely associated with feature extraction. We offer the ‘windowed sampling’ hypothesis for active sensing: that rats can estimate an object’s spatial features by integrating mechanical information across whiskers during brief (25–60 ms) windows of ‘haptic enclosure’ with the whiskers, a motion that resembles a hand grasp. PMID:27632212

Development of standard operating procedures of Habbe Shifa: A polyherbal Unani formulation.

PubMed

Tarannum, Asira; Shamsi, Shariq; Zaman, Roohi

2013-07-01

Unani medicines are being used since antiquity. However, in spite of their efficacy, they have been widely criticized due to lack of standardization and poor quality presentation. For this reason, application of good manufacturing practices and development of standard operating procedures (SOPs) in the manufacture of herbal medicines became an essential tool to assure their quality. Therefore, the objective of the study was to develop the SOP of Habbe Shifa (HS) regarding the particle size (PS), binder, temperature of drying, and duration of drying. In this study, 24 batches of HS were prepared according to the instructions given in formulary to develop SOP. Three particle sizes (i.e., 80, 100, and 120 No. Mesh sieve), were taken for preparation of pills. Water and Samaghe Arabi (Gum Acacia mucilage [GAM]) were used as binder for preparing the lubdi (mass) in different batches. Different temperature and duration of drying were used to dry the pills in hot air oven to get satisfactory results. All the batches were assessed three times for hardness, friability, and disintegration time and mean regarded as standard parameter value. The batch with 150 μm PS (100 mesh sieve), 5% w/w GAM used as a binder, dried at 90°C for 120 min showed hardness 3.50 ± 0.00 kg/cm, friability 0.02 ± 0.003%, and disintegration time 25.00 ± 0.57 min, which showed most appropriate result among all batches and considered as final batch. Its SOP may be used for future reference which can help in setting up regulatory limit to assure the quality of Unani medicines.

Metonymy and reference-point errors in novice programming

NASA Astrophysics Data System (ADS)

Miller, Craig S.

2014-07-01

When learning to program, students often mistakenly refer to an element that is structurally related to the element that they intend to reference. For example, they may indicate the attribute of an object when their intention is to reference the whole object. This paper examines these reference-point errors through the context of metonymy. Metonymy is a rhetorical device where the speaker states a referent that is structurally related to the intended referent. For example, the following sentence states an office bureau but actually refers to a person working at the bureau: The tourist asked the travel bureau for directions to the museum. Drawing upon previous studies, I discuss how student reference errors may be consistent with the use of metonymy. In particular, I hypothesize that students are more likely to reference an identifying element even when a structurally related element is intended. I then present two experiments, which produce results consistent with this analysis. In both experiments, students are more likely to produce reference-point errors that involve identifying attributes than descriptive attributes. Given these results, I explore the possibility that students are relying on habits of communication rather than the mechanistic principles needed for successful programming. Finally I discuss teaching interventions using live examples and how metonymy may be presented to non-computing students as pedagogy for computational thinking.

Math Tracks: What Pace in Math Is Best for the Middle School Child?

ERIC Educational Resources Information Center

Morrison, Michelle

2011-01-01

Mathematics is a critical part of academic preparation of the middle school child, or, as Dr. Maria Montessori would refer to them, children in the third plane of development. Montessori educators are sincere in their endeavors not only to prepare young students for further studies of math and the application of math in their world and careers,…

16 CFR 801.21 - Securities and cash not considered assets when acquired.

Code of Federal Regulations, 2011 CFR

2011-01-01

... regularly prepared balance sheet of “A” referred to in § 801.11—the voting securities of X must be reflected... in “A's” next regularly prepared balance sheet for purposes of section 7A(a)(2). 3. In example 1... when acquired. 801.21 Section 801.21 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS...

INSTRUCTIONAL PROGRAMMING PROCEDURES, A PROGRAMED COURSE IN THE BASIC METHODS AND TECHNIQUES OF PREPARING PROGRAMED INSTRUCTIONAL MATERIALS.

ERIC Educational Resources Information Center

DETERLINE, WILLIAM A.

A PROGRAMED COURSE IN METHODS AND TECHNIQUES OF PREPARING PROGRAMED INSTRUCTIONAL MATERIALS WAS PRESENTED IN THIS DOCUMENT. AN ATTEMPT WAS MADE TO TEACH BASIC PROCEDURES WELL ENOUGH TO PRODUCE AN EMBRYO PROGRAMER AND TO PROVIDE HIM WITH REFERENCES HE WOULD NEED IN ORDER TO PRODUCE PROGRAMS. INCLUDED WERE PROGRAMED INSTRUCTIONS ON PREPARATORY…

Specificities of Sightseeing Foot Tour Arrangement for History Related Street with Regard to Karl Marx Street in the Town of Irkutsk

NASA Astrophysics Data System (ADS)

Kulakov, A. I.; Shishkanov, V. S.

2017-11-01

The paper is devoted to the preparation of an innovative foot itinerary for tourists in Karl Marx Street in the town of Irkutsk. Methodology on preparation of sightseeing tours has been analysed by the authors. The analysis of the methodology has facilitated selecting the criteria to classify the excursions as well as the criteria for assessing and shortlisting the objects for excursion exposure. Some chosen criteria being used in tour arrangement and certain specificities of tour preparation have been revealed which are characteristic particularly for Karl Marx Street as a history-related one. It is also proved in the paper that the itinerary prepared for tourists is in full correspondence with the key innovation objectives in tourism.

Identification of the monobrominated derivative of Acid Red 52 (Food Red No. 106) in pickled vegetables.

PubMed

Ochi, Naoki; Okuda, Tetsuya; Fujii, Hisashi

2016-09-01

Two unknown dyes (purple and purplish-red) were detected by TLC in two pickled vegetable (sakura-zuke daikon) samples containing Acid Red 52 (AR) and New Coccine as food colorants. HPLC with diode-array detection and LC/MS analyses suggested that the purple dye is monobrominated AR and the purplish-red dye is its N-desethyl derivative, which would be generated mainly during sample preparation. For the identification of the purple dye, a reference compound was prepared by bromination of AR followed by isolation of the monobrominated AR, the structure of which was elucidated as 4'-brominated AR (4'BrAR) by LC/ToF-MS and (1)H-NMR spectroscopy. The purple dye was confirmed as 4'BrAR by comparison of its retention time, ultraviolet-visible spectrum and mass spectrum with those of the prepared reference compound. To our knowledge, this is the first report of the detection of 4'BrAR in foods.

Supervising Athletic Trainers' Perceptions of Graduate Assistant Athletic Trainers' Professional Preparation

ERIC Educational Resources Information Center

Thrasher, Ashley B.; Walker, Stacy E.; Hankemeier, Dorice A.; Pitney, William A.

2015-01-01

Context: Recent debate has ensued regarding the readiness of newly credentialed athletic trainers (ATs) to function as independent clinicians. Some ATs believe the professional preparation of athletic training students is not adequate. Objective: To describe supervisors' perceptions regarding the preparation of college graduate assistants (GAs) to…

Modifications to the NIST reference measurement procedure (RMP) for the determination of serum glucose by isotope dilution gas chromatography/mass spectrometry.

PubMed

Prendergast, Jocelyn L; Sniegoski, Lorna T; Welch, Michael J; Phinney, Karen W

2010-07-01

The definitive method (DM), now known as the reference measurement procedure (RMP), for the analysis of glucose in serum was originally published in 1982 by the National Institute of Standards and Technology (NIST). Over the years the method has been subject to a number of modifications to adapt to newer technologies and simplify sample preparation. We discuss here an adaptation of the method associated with serum glucose measurements using a modified isotope dilution gas chromatography/mass spectrometry (ID-GC/MS) method. NIST has used this modified method to certify the concentrations of glucose in SRM 965b, Glucose in Frozen Human Serum, and SRM 1950, Metabolites in Human Plasma. Comparison of results from the revised method with certified values for existing Standard Reference Materials (SRMs) demonstrated that these modifications have not affected the quality of the measurements, giving both good precision and accuracy, while reducing the sample preparation time by a day and a half.

International energy outlook 1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-05-01

This International Energy Outlook presents historical data from 1970 to 1993 and EIA`s projections of energy consumption and carbon emissions through 2015 for 6 country groups. Prospects for individual fuels are discussed. Summary tables of the IEO96 world energy consumption, oil production, and carbon emissions projections are provided in Appendix A. The reference case projections of total foreign energy consumption and of natural gas, coal, and renewable energy were prepared using EIA`s World Energy Projection System (WEPS) model. Reference case projections of foreign oil production and consumption were prepared using the International Energy Module of the National Energy Modeling Systemmore » (NEMS). Nuclear consumption projections were derived from the International Nuclear Model, PC Version (PC-INM). Alternatively, nuclear capacity projections were developed using two methods: the lower reference case projections were based on analysts` knowledge of the nuclear programs in different countries; the upper reference case was generated by the World Integrated Nuclear Evaluation System (WINES)--a demand-driven model. In addition, the NEMS Coal Export Submodule (CES) was used to derive flows in international coal trade. As noted above, foreign projections of electricity demand are now projected as part of the WEPS. 64 figs., 62 tabs.« less

Advanced Curation Activities at NASA: Implications for Astrobiological Studies of Future Sample Collections

NASA Technical Reports Server (NTRS)

McCubbin, F. M.; Evans, C. A.; Fries, M. D.; Harrington, A. D.; Regberg, A. B.; Snead, C. J.; Zeigler, R. A.

2017-01-01

The Astromaterials Acquisition and Curation Office (henceforth referred to herein as NASA Curation Office) at NASA Johnson Space Center (JSC) is responsible for curating all of NASA's extraterrestrial samples. Under the governing document, NASA Policy Directive (NPD) 7100.10F JSC is charged with curation of all extraterrestrial material under NASA control, including future NASA missions. The Directive goes on to define Curation as including documentation, preservation, preparation, and distribution of samples for re-search, education, and public outreach. Here we briefly describe NASA's astromaterials collections and our ongoing efforts related to enhancing the utility of our current collections as well as our efforts to prepare for future sample return missions. We collectively refer to these efforts as advanced curation.

The determination of elements in herbal teas and medicinal plant formulations and their tisanes.

PubMed

Pohl, Pawel; Dzimitrowicz, Anna; Jedryczko, Dominika; Szymczycha-Madeja, Anna; Welna, Maja; Jamroz, Piotr

2016-10-25

Elemental analysis of herbal teas and their tisanes is aimed at assessing their quality and safety in reference to specific food safety regulations and evaluating their nutritional value. This survey is dedicated to atomic spectroscopy and mass spectrometry element detection methods and sample preparation procedures used in elemental analysis of herbal teas and medicinal plant formulations. Referring to original works from the last 15 years, particular attention has been paid to tisane preparation, sample matrix decomposition, calibration and quality assurance of results in elemental analysis of herbal teas by different atomic and mass spectrometry methods. In addition, possible sources of elements in herbal teas and medicinal plant formulations have been discussed. Copyright © 2016 Elsevier B.V. All rights reserved.

EOS Laser Atmosphere Wind Sounder (LAWS) investigation

NASA Technical Reports Server (NTRS)

1996-01-01

In this final report, the set of tasks that evolved from the Laser Atmosphere Wind Sounder (LAWS) Science Team are reviewed, the major accomplishments are summarized, and a complete set of resulting references provided. The tasks included preparation of a plan for the LAWS Algorithm Development and Evolution Laboratory (LADEL); participation in the preparation of a joint CNES/NASA proposal to build a space-based DWL; involvement in the Global Backscatter Experiments (GLOBE); evaluation of several DWL concepts including 'Quick-LAWS', SPNDL and several direct detection technologies; and an extensive series of system trade studies and Observing System Simulation Experiments (OSSE's). In this report, some of the key accomplishments are briefly summarized with reference to interim reports, special reports, conference/workshop presentations, and publications.

A randomized, crossover pharmacokinetic study comparing generic tacrolimus vs. the reference formulation in subpopulations of kidney transplant patients.

PubMed

Bloom, R D; Trofe-Clark, J; Wiland, A; Alloway, R R

2013-01-01

An exploratory, post hoc analysis was performed using data from a prospective, multicenter, open-label, randomized, two-period (14 d per period), two-sequence, crossover, steady-state pharmacokinetic study comparing generic tacrolimus (Sandoz) vs. reference tacrolimus in stable renal transplant patients receiving their pre-study twice-daily dose. Pharmacokinetic parameters were compared in 68 patients according to gender, African American ethnicity, the presence or absence of diabetes, and use of steroids. The ratios of tacrolimus AUC0-12 h , Cmax , and C12 with generic vs. reference tacrolimus were calculated using the geometric mean (GM) of dose-normalized values at days 14 and 28. Mean (SD) tacrolimus dose at baseline was 5.7 (4.2) mg/d. There were no consistent differences in dose-normalized AUC0-12 h , C12 , Cmax, or tmax between the generic and reference preparations within subpopulations. The 90% confidence intervals (CI) for the ratios of dose-normalized AUC0-12 h and C12 with generic vs. reference tacrolimus were within 80-125% for all subpopulations, as were 90% CIs for Cmax other than for females, African Americans, and non-diabetics, which is not unexpected given the wide variability of tacrolimus Cmax and the small subpopulation sizes. These exploratory results suggest that this generic tacrolimus preparation would be expected to offer comparable bioavailability to the reference drug in these patient subpopulations. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

32 CFR 562.4 - Objectives.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 3 2014-07-01 2014-07-01 false Objectives. 562.4 Section 562.4 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY ORGANIZED RESERVES RESERVE OFFICERS' TRAINING CORPS § 562.4 Objectives. The objectives of the ROTC program are to: (a) Attract, motivate, and prepare...

Two-Year-Olds Exclude Novel Objects as Potential Referents of Novel Words Based on Pragmatics

ERIC Educational Resources Information Center

Grassmann, Susanne; Stracke, Maren; Tomasello, Michael

2009-01-01

Many studies have established that children tend to exclude objects for which they already have a name as potential referents of novel words. In the current study we asked whether this exclusion can be triggered by social-pragmatic context alone without pre-existing words as blockers. Two-year-old children watched an adult looking at a novel…

Preparing for Rural Ministry: A Qualitative Analysis of Curriculum Used in Theological Education to Prepare Clergy for Ministry in a Rural Context

ERIC Educational Resources Information Center

Sherin, Kenneth Mark

2012-01-01

Increasing the capacity of rural clergy through their educational preparation is important. Unfortunately, there is lack of research and understanding about the educational preparation of clergy to work in rural communities. This qualitative content analysis of course descriptions, goals and objectives and an analysis of the content covered in the…

Analyzing and designing object-oriented missile simulations with concurrency

NASA Astrophysics Data System (ADS)

Randorf, Jeffrey Allen

2000-11-01

A software object model for the six degree-of-freedom missile modeling domain is presented. As a precursor, a domain analysis of the missile modeling domain was started, based on the Feature-Oriented Domain Analysis (FODA) technique described by the Software Engineering Institute (SEI). It was subsequently determined the FODA methodology is functionally equivalent to the Object Modeling Technique. The analysis used legacy software documentation and code from the ENDOSIM, KDEC, and TFrames 6-DOF modeling tools, including other technical literature. The SEI Object Connection Architecture (OCA) was the template for designing the object model. Three variants of the OCA were considered---a reference structure, a recursive structure, and a reference structure with augmentation for flight vehicle modeling. The reference OCA design option was chosen for maintaining simplicity while not compromising the expressive power of the OMT model. The missile architecture was then analyzed for potential areas of concurrent computing. It was shown how protected objects could be used for data passing between OCA object managers, allowing concurrent access without changing the OCA reference design intent or structure. The implementation language was the 1995 release of Ada. OCA software components were shown how to be expressed as Ada child packages. While acceleration of several low level and other high operations level are possible on proper hardware, there was a 33% degradation of 4th order Runge-Kutta integrator performance of two simultaneous ordinary differential equations using Ada tasking on a single processor machine. The Defense Department's High Level Architecture was introduced and explained in context with the OCA. It was shown the HLA and OCA were not mutually exclusive architectures, but complimentary. HLA was shown as an interoperability solution, with the OCA as an architectural vehicle for software reuse. Further directions for implementing a 6-DOF missile modeling environment are discussed.

Chirped pulse digital holography for measuring the sequence of ultrafast optical wavefronts

NASA Astrophysics Data System (ADS)

Karasawa, Naoki

2018-04-01

Optical setups for measuring the sequence of ultrafast optical wavefronts using a chirped pulse as a reference wave in digital holography are proposed and analyzed. In this method, multiple ultrafast object pulses are used to probe the temporal evolution of ultrafast phenomena and they are interfered with a chirped reference wave to record a digital hologram. Wavefronts at different times can be reconstructed separately from the recorded hologram when the reference pulse can be treated as a quasi-monochromatic wave during the pulse width of each object pulse. The feasibility of this method is demonstrated by numerical simulation.

[Development and application of reference materials containing mixed degradation products of amoxicillin and ampicillin].

PubMed

Li, Wei; Zhang, Wei-Qing; Li, Xiang; Hu, Chang-Qin

2014-09-01

Reference materials containing mixed degradation products of amoxicillin and ampicillin were developed after optimization of preparation processes. The target impurities were obtained by controlled stress testing, and each major component was identified with HPLC-MS and compared with single traceable reference standard each. The developed reference materials were applied to system suitability test for verifying HPLC system performed in accordance with set forth in China Pharmacopeia and identification of major impurities in samples based on retention and spectra information, which have advantages over the methods put forth in foreign pharmacopoeias. The development and application of the reference materials offer an effective way for rapid identification of impurities in chromatograms, and provide references for analyzing source of impurities and evaluation of drug quality.

Common path in-line holography using enhanced joint object reference digital interferometers

PubMed Central

Kelner, Roy; Katz, Barak; Rosen, Joseph

2014-01-01

Joint object reference digital interferometer (JORDI) is a recently developed system capable of recording holograms of various types [Opt. Lett. 38(22), 4719 (2013)24322115]. Presented here is a new enhanced system design that is based on the previous JORDI. While the previous JORDI has been based purely on diffractive optical elements, displayed on spatial light modulators, the present design incorporates an additional refractive objective lens, thus enabling hologram recording with improved resolution and increased system applicability. Experimental results demonstrate successful hologram recording for various types of objects, including transmissive, reflective, three-dimensional, phase and highly scattering objects. The resolution limit of the system is analyzed and experimentally validated. Finally, the suitability of JORDI for microscopic applications is verified as a microscope objective based configuration of the system is demonstrated. PMID:24663838

Preparation of YBa2Cu3O7 High Tc Superconducting Coatings by Plasma Spraying

NASA Astrophysics Data System (ADS)

Danroc, J.; Lacombe, J.

The following sections are included: * INTRODUCTION * THE COMPOUND YBa2Cu3O7-δ * Structure * Critical temperature * Critical current density * Phase equilibria in the YBaCuO system * PREPARATION OF YBa2Cu3O7 COATINGS * General organisation of the preparation process * The powder * Hot plasma spraying of YBa2Cu3O7 * The post-spraying thermal treatment * CHARACTERISTICS OF THE YBa2Cu3O7-δ COATINGS * Chemical composition * Crystalline structure * Morphology of the coatings * Electrical and magnetic characteristics * Conclusion * REFERENCES

[SCHWABE Company's patent portfolio of Ginkgo biloba preparation].

PubMed

Liu, Wei; Cheng, Xin-Min; Geng, Dong-Mei; Tan, Wei; Zou, Wen-Jun

2014-09-01

SCHWABE Company in German is the first and largest manufacturer of Ginkgo biloba preparation. The company not only has leading technology in this field, but also protects its own market effectively through the high quality of patent drafting and exactly patent layout. Based on multi-angle analysis for patent portfolio of G. biloba preparation at application time, legal status, globally layout, Chinese layout, the article provides technical reference of research and development of G. biloba, also provides valuable experience of traditonal Chinese medicine patent portfolio layout for Chinese enterprises.

Using Vision Metrology System for Quality Control in Automotive Industries

NASA Astrophysics Data System (ADS)

Mostofi, N.; Samadzadegan, F.; Roohy, Sh.; Nozari, M.

2012-07-01

The need of more accurate measurements in different stages of industrial applications, such as designing, producing, installation, and etc., is the main reason of encouraging the industry deputy in using of industrial Photogrammetry (Vision Metrology System). With respect to the main advantages of Photogrammetric methods, such as greater economy, high level of automation, capability of noncontact measurement, more flexibility and high accuracy, a good competition occurred between this method and other industrial traditional methods. With respect to the industries that make objects using a main reference model without having any mathematical model of it, main problem of producers is the evaluation of the production line. This problem will be so complicated when both reference and product object just as a physical object is available and comparison of them will be possible with direct measurement. In such case, producers make fixtures fitting reference with limited accuracy. In practical reports sometimes available precision is not better than millimetres. We used a non-metric high resolution digital camera for this investigation and the case study that studied in this paper is a chassis of automobile. In this research, a stable photogrammetric network designed for measuring the industrial object (Both Reference and Product) and then by using the Bundle Adjustment and Self-Calibration methods, differences between the Reference and Product object achieved. These differences will be useful for the producer to improve the production work flow and bringing more accurate products. Results of this research, demonstrate the high potential of proposed method in industrial fields. Presented results prove high efficiency and reliability of this method using RMSE criteria. Achieved RMSE for this case study is smaller than 200 microns that shows the fact of high capability of implemented approach.

Reference frames in allocentric representations are invariant across static and active encoding

PubMed Central

Chan, Edgar; Baumann, Oliver; Bellgrove, Mark A.; Mattingley, Jason B.

2013-01-01

An influential model of spatial memory—the so-called reference systems account—proposes that relationships between objects are biased by salient axes (“frames of reference”) provided by environmental cues, such as the geometry of a room. In this study, we sought to examine the extent to which a salient environmental feature influences the formation of spatial memories when learning occurs via a single, static viewpoint and via active navigation, where information has to be integrated across multiple viewpoints. In our study, participants learned the spatial layout of an object array that was arranged with respect to a prominent environmental feature within a virtual arena. Location memory was tested using judgments of relative direction. Experiment 1A employed a design similar to previous studies whereby learning of object-location information occurred from a single, static viewpoint. Consistent with previous studies, spatial judgments were significantly more accurate when made from an orientation that was aligned, as opposed to misaligned, with the salient environmental feature. In Experiment 1B, a fresh group of participants learned the same object-location information through active exploration, which required integration of spatial information over time from a ground-level perspective. As in Experiment 1A, object-location information was organized around the salient environmental cue. Taken together, the findings suggest that the learning condition (static vs. active) does not affect the reference system employed to encode object-location information. Spatial reference systems appear to be a ubiquitous property of spatial representations, and might serve to reduce the cognitive demands of spatial processing. PMID:24009595

Quality assessment for color reproduction using a blind metric

NASA Astrophysics Data System (ADS)

Bringier, B.; Quintard, L.; Larabi, M.-C.

2007-01-01

This paper deals with image quality assessment. This field plays nowadays an important role in various image processing applications. Number of objective image quality metrics, that correlate or not, with the subjective quality have been developed during the last decade. Two categories of metrics can be distinguished, the first with full-reference and the second with no-reference. Full-reference metric tries to evaluate the distortion introduced to an image with regards to the reference. No-reference approach attempts to model the judgment of image quality in a blind way. Unfortunately, the universal image quality model is not on the horizon and empirical models established on psychophysical experimentation are generally used. In this paper, we focus only on the second category to evaluate the quality of color reproduction where a blind metric, based on human visual system modeling is introduced. The objective results are validated by single-media and cross-media subjective tests.

Transforming Teacher Preparation to Ensure Long-Term Improvement in STEM Teaching

ERIC Educational Resources Information Center

Hiebert, James

2013-01-01

An alternative mathematics preparation program for K-8 teachers is described as an existence proof that steadily increasing effectiveness of STEM (science, technology, engineering, and mathematics) preparation is possible. The program is based on treating every lesson in each of five mathematics content and methods courses as objects of study.…

Utility of eButton images for identifying food preparation behaviors and meal-related tasks in adolescents

USDA-ARS?s Scientific Manuscript database

Food preparation skills may encourage healthy eating. Traditional assessment of child food preparation employs self- or parent proxy-reporting methods, which are prone to error. The eButton is a wearable all-day camera that has promise as an objective, passive method for measuring child food prepara...

Preparing Principals to Improve Student Achievement

ERIC Educational Resources Information Center

Corcoran, Roisin P.

2017-01-01

Background: The growing interest in principal effectiveness as a means of improving teaching and student learning has led to a focus on the quality of principal preparation programs (PPPs) with calls for the adoption of PPP accountability systems similar to those of teacher preparation programs. Objective: The purpose of the present study is to…

Site preparation for wildlife

Treesearch

Ralph W. Dimmick

1989-01-01

Site preparation-whether for timber and/or wildlife objectives - can influence the quality of wildlife habitat on the site and surrounding forest for the entire rotation period of the regenerated stand. The site preparation you select will help determine the species and numbers of wildlife that use the stand as the stand progresses from regeneration through maturity....

Preparation of Teacher-Trainees in Pedagogy in Kenyan Universities

ERIC Educational Resources Information Center

Genvieve, Nasimiyu

2017-01-01

There has been a concern about the quality of school teachers being prepared at the university especially in pedagogy. The main objective of the study was to investigate the preparation of teacher-trainees in pedagogy in Kenyan universities.The theoretical framework of the study was based on Shulman's concept of pedagogical content knowledge. The…

Alternatives for Developing User Documentation for Applications Software

DTIC Science & Technology

1991-09-01

style that is designed to match adult reading behaviors, using reader-based writing techniques, developing effective graphics , creating reference aids...involves research, analysis, design , and testing. The writer must have a solid understanding of the technical aspects of the document being prepared, good...ABSTRACT The preparation of software documentation is an iterative process that involves research, analysis, design , and testing. The writer must have

Quantum-chemical Calculations in the Study of Antitumour Compounds

NASA Astrophysics Data System (ADS)

Luzhkov, V. B.; Bogdanov, G. N.

1986-01-01

The results of quantum-chemical calculations on antitumour preparations concerning the mechanism of their action at the electronic and molecular levels and structure-activity correlations are discussed in this review. Preparations whose action involves alkylating and free-radial mechanisms, complex-forming agents, and antimetabolites are considered. Modern quantum-chemical methods for calculations on biologically active substances are described. The bibliography includes 106 references.

Storage of Buffy-coat-derived platelets in additive solutions: in vitro effects on platelets prepared by the novel TACSI system and stored in plastic containers with different gas permeability.

PubMed

Sandgren, P; Hild, M; Sjödin, A; Gulliksson, H

2010-11-01

The novel TACSI system is designed for automated preparation of platelets (PLTs) from pooled buffy coats (BCs). One TACSI device will handle 6 units at the same time. The aim of our in vitro study is to investigate the effects of using this automated equipment with subsequent storage in two different plastic containers and to compare these results with PLTs prepared by the OrbiSac system. Buffy-coat-derived PLTs (n=8) were prepared by using the TACSI system, including storage in polyvinyl chloride (PVC)-based plastic containers with di, n-decyl phthalate (DnDP) (TACSI R) and BTHC (TACSI T)-based plasticizers. As a reference, the OrbiSac System was used to prepare PLTs (n=8) with subsequent storage in a PVC plastic container with a citrate-based plasticizer (BTHC). In total, 16 TACSI and eight reference units, supplied by approximately 30% plasma and 70% SSP+, were analysed for various in vitro variables during the 7-day storage period. No significant difference in PLT counts, LDH, mean platelet volume (MPV) and adenosine triphosphate between the groups was detected. Glucose was lower (P<0·05) and lactate was higher (P<0·05) in TACSI R vs. OrbiSac. With exception of day 7 (P<0·05 TACSI R vs. OrbiSac), HSR reactivity were not different between groups. Extent of shape change was lower and CD62P higher in TACSI T when compared with TACSI R and OrbiSac units (P<0·05). pH was maintained at >6·8 (day 7) and swirling remained at the highest level (score=2) for all units throughout storage. Platelets prepared by the TACSI system with subsequent storage in two different PVC-based plastic containers were equivalent to reference PLTs with regard to in vitro characteristics during 7 days of storage. © 2010 The Author(s). Vox Sanguinis © 2010 International Society of Blood Transfusion.

Hardware Evaluation Of Heavy Truck Side And Rear Object Detection Systems

DOT National Transportation Integrated Search

1995-01-01

This paper focuses on two types of electronics-based object detection systems for heavy truck applications: those sensing the presence of objects to the rear of the vehicle (referred to as Rear Object Detection Systems, or RODS) and those sensing the...

Importance of baseline specification in evaluating conservation interventions and achieving no net loss of biodiversity.

PubMed

Bull, J W; Gordon, A; Law, E A; Suttle, K B; Milner-Gulland, E J

2014-06-01

There is an urgent need to improve the evaluation of conservation interventions. This requires specifying an objective and a frame of reference from which to measure performance. Reference frames can be baselines (i.e., known biodiversity at a fixed point in history) or counterfactuals (i.e., a scenario that would have occurred without the intervention). Biodiversity offsets are interventions with the objective of no net loss of biodiversity (NNL). We used biodiversity offsets to analyze the effects of the choice of reference frame on whether interventions met stated objectives. We developed 2 models to investigate the implications of setting different frames of reference in regions subject to various biodiversity trends and anthropogenic impacts. First, a general analytic model evaluated offsets against a range of baseline and counterfactual specifications. Second, a simulation model then replicated these results with a complex real world case study: native grassland offsets in Melbourne, Australia. Both models showed that achieving NNL depended upon the interaction between reference frame and background biodiversity trends. With a baseline, offsets were less likely to achieve NNL where biodiversity was decreasing than where biodiversity was stable or increasing. With a no-development counterfactual, however, NNL was achievable only where biodiversity was declining. Otherwise, preventing development was better for biodiversity. Uncertainty about compliance was a stronger determinant of success than uncertainty in underlying biodiversity trends. When only development and offset locations were considered, offsets sometimes resulted in NNL, but not across an entire region. Choice of reference frame determined feasibility and effort required to attain objectives when designing and evaluating biodiversity offset schemes. We argue the choice is thus of fundamental importance for conservation policy. Our results shed light on situations in which biodiversity offsets may be an inappropriate policy instrument.

Overseas Assignment of Sponsors who have Children with Disabilities Who Are Space-Required Students in the Department of Defense Dependents Schools (DoDDS)

DTIC Science & Technology

1992-03-01

reference (d)), general medical care is provided to family members on a space-available basis. 7. ’ndivuglzed Education Program. ( IEP ) A written document...participate in and benefit from his or her education. The IEP is further described in, and prepared under, reference (b). 8. pin oint Location. A specific...member the special education or related services required by an IEP or an evaluation required by DoD Instruction 1342.12 (reference (b)). 5. This

"They Prepared Me to Be a Teacher, but Not a Culturally Responsive Navajo Teacher for Navajo Kids": A Tribal Critical Race Theory Analysis of an Indigenous Teacher Preparation Program

ERIC Educational Resources Information Center

Castagno, Angelina E.

2012-01-01

This article argues that federally-funded Indigenous teacher preparation programs housed at mainstream, predominantly White universities can be colonial and thus require significant focused work in order to ensure that they are not. The article has three interrelated objectives: first, to discuss efforts to prepare Indigenous teachers for…

Mental Health Issues among College Students: Who Gets Referred for Psychopharmacology Evaluation?

ERIC Educational Resources Information Center

Kirsch, Daniel J.; Doerfler, Leonard A.; Truong, Debbie

2015-01-01

Objective: To describe diagnostic and psychotropic medication prescription characteristics among college students referred by college counseling centers for psychopharmacologic evaluation. Participants: Participants were 540 college students referred by 6 college counseling centers in Massachusetts between November 2005 and May 2011. Methods:…

Employment references: defamation law in the clinical laboratory.

PubMed

Parks, D G

1993-01-01

The law of defamation and the risks involved in issuing employment references are discussed. A hypothetical scenario is used to illustrate the legal standards governing the tort of defamation and to apply those standards to employment references. Practical suggestions for a "controlled reference" policy are provided, with the objective of allowing for responsible exchange of employment information and avoiding a defamation lawsuit.

Wide field of view common-path lateral-shearing digital holographic interference microscope

NASA Astrophysics Data System (ADS)

Vora, Priyanka; Trivedi, Vismay; Mahajan, Swapnil; Patel, Nimit; Joglekar, Mugdha; Chhaniwal, Vani; Moradi, Ali-Reza; Javidi, Bahram; Anand, Arun

2017-12-01

Quantitative three-dimensional (3-D) imaging of living cells provides important information about the cell morphology and its time variation. Off-axis, digital holographic interference microscopy is an ideal tool for 3-D imaging, parameter extraction, and classification of living cells. Two-beam digital holographic microscopes, which are usually employed, provide high-quality 3-D images of micro-objects, albeit with lower temporal stability. Common-path digital holographic geometries, in which the reference beam is derived from the object beam, provide higher temporal stability along with high-quality 3-D images. Self-referencing geometry is the simplest of the common-path techniques, in which a portion of the object beam itself acts as the reference, leading to compact setups using fewer optical elements. However, it has reduced field of view, and the reference may contain object information. Here, we describe the development of a common-path digital holographic microscope, employing a shearing plate and converting one of the beams into a separate reference by employing a pin-hole. The setup is as compact as self-referencing geometry, while providing field of view as wide as that of a two-beam microscope. The microscope is tested by imaging and quantifying the morphology and dynamics of human erythrocytes.

Wide field of view common-path lateral-shearing digital holographic interference microscope.

PubMed

Vora, Priyanka; Trivedi, Vismay; Mahajan, Swapnil; Patel, Nimit; Joglekar, Mugdha; Chhaniwal, Vani; Moradi, Ali-Reza; Javidi, Bahram; Anand, Arun

2017-12-01

Quantitative three-dimensional (3-D) imaging of living cells provides important information about the cell morphology and its time variation. Off-axis, digital holographic interference microscopy is an ideal tool for 3-D imaging, parameter extraction, and classification of living cells. Two-beam digital holographic microscopes, which are usually employed, provide high-quality 3-D images of micro-objects, albeit with lower temporal stability. Common-path digital holographic geometries, in which the reference beam is derived from the object beam, provide higher temporal stability along with high-quality 3-D images. Self-referencing geometry is the simplest of the common-path techniques, in which a portion of the object beam itself acts as the reference, leading to compact setups using fewer optical elements. However, it has reduced field of view, and the reference may contain object information. Here, we describe the development of a common-path digital holographic microscope, employing a shearing plate and converting one of the beams into a separate reference by employing a pin-hole. The setup is as compact as self-referencing geometry, while providing field of view as wide as that of a two-beam microscope. The microscope is tested by imaging and quantifying the morphology and dynamics of human erythrocytes. (2017) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE).

The positive side of a negative reference: the delay between linguistic processing and common ground

PubMed Central

Noveck, Ira; Rivera, Natalia; Jaume-Guazzini, Francisco

2017-01-01

Interlocutors converge on names to refer to entities. For example, a speaker might refer to a novel looking object as the jellyfish and, once identified, the listener will too. The hypothesized mechanism behind such referential precedents is a subject of debate. The common ground view claims that listeners register the object as well as the identity of the speaker who coined the label. The linguistic view claims that, once established, precedents are treated by listeners like any other linguistic unit, i.e. without needing to keep track of the speaker. To test predictions from each account, we used visual-world eyetracking, which allows observations in real time, during a standard referential communication task. Participants had to select objects based on instructions from two speakers. In the critical condition, listeners sought an object with a negative reference such as not the jellyfish. We aimed to determine the extent to which listeners rely on the linguistic input, common ground or both. We found that initial interpretations were based on linguistic processing only and that common ground considerations do emerge but only after 1000 ms. Our findings support the idea that—at least temporally—linguistic processing can be isolated from common ground. PMID:28386440

Vocabulary comprehension and strategies in name construction among children using aided communication.

PubMed

Deliberato, Débora; Jennische, Margareta; Oxley, Judith; Nunes, Leila Regina d'Oliveira de Paula; Walter, Cátia Crivelenti de Figueiredo; Massaro, Munique; Almeida, Maria Amélia; Stadskleiv, Kristine; Basil, Carmen; Coronas, Marc; Smith, Martine; von Tetzchner, Stephen

2018-03-01

Vocabulary learning reflects the language experiences of the child, both in typical and atypical development, although the vocabulary development of children who use aided communication may differ from children who use natural speech. This study compared the performance of children using aided communication with that of peers using natural speech on two measures of vocabulary knowledge: comprehension of graphic symbols and labeling of common objects. There were 92 participants not considered intellectually disabled in the aided group. The reference group consisted of 60 participants without known disorders. The comprehension task consisted of 63 items presented individually in each participant's graphic system, together with four colored line drawings. Participants were required to indicate which drawing corresponded to the symbol. In the expressive labelling task, 20 common objects presented in drawings had to be named. Both groups indicated the correct drawing for most of the items in the comprehension tasks, with a small advantage for the reference group. The reference group named most objects quickly and accurately, demonstrating that the objects were common and easily named. The aided language group named the majority correctly and in addition used a variety of naming strategies; they required more time than the reference group. The results give insights into lexical processing in aided communication and may have implications for aided language intervention.

The Miner, His Job and His Environment: A Review and Bibliography of Selected Recent Research on Human Performance.

ERIC Educational Resources Information Center

Fried, Charles; And Others

In a survey of the state of the art in ergonomics (human factors) as it has been applied to coal mining, approximately 1,200 references in the published literature both foreign and domestic were located. Abstracts of 49 references were prepared on such topics as the effects of environmental stress on health and productivity, accident prevention…

Special Operations Forces Reference Manual. Fourth Edition

DTIC Science & Technology

2015-06-01

Special Operations Forces Reference Manual Fourth Edition The JSOU Press MacDill AFB, Florida June 2015 Prepared by Joint Special Operations...other national and international security decision-makers, both military and civilian, through teaching, outreach, and research in the science and art...Luke First Edition, June 2005 (Revised July 2006) Second Edition, August 2008 Third Edition, September 2011 Fourth Edition, June 2015 This work was

Language Problems in Africa; A Bibliography (1946-1967) and Summary of the Present Situation, with Special Reference to Kenya, Tanzania and Uganda.

ERIC Educational Resources Information Center

Molnos, Angela, Comp.

The present Information Circular covering the language situation in East Africa has been prepared as a bibliographic reference tool for specialists, universities, and libraries. The introductory section describes the work of EARIC (East African Research Information Centre), which is sponsored by the East African Academy and financed by the Ford…

Documentation for the machine-readable version of the lick Saturn-Voyager Reference Star Catalogue

NASA Technical Reports Server (NTRS)

Warren, W. H., Jr.

1982-01-01

The machine-readable version of the catalog is described. The catalog was prepared in order to determine accurate equatorial coordinates for reference stars in a band of sky against which cameras of the Voyager spacecraft were aligned for observations in the region of Saturn during the flyby. Tape contents and characteristics are described and a sample listing presented.

Preparation and infrared/raman classification of 630 spectroscopically encoded styrene copolymers.

PubMed

Fenniri, Hicham; Chun, Sangki; Terreau, Owen; Bravo-Vasquez, Juan-Pablo

2008-01-01

The barcoded resins (BCRs) were introduced recently as a platform for encoded combinatorial chemistry. One of the main challenges yet to be overcome is the demonstration that a large number of BCRs could be generated and classified with high confidence. Here, we describe the synthesis and classification of 630 polystyrene-based copolymers prepared from the combinatorial association of 15 spectroscopically active styrene monomers. Each of the 630 copolymers displayed a unique vibrational fingerprint (infrared and Raman), which was converted into a spectral vector. To each of the 630 copolymers, a vector of the known (reference) composition was assigned. Unknown (prediction) vectors were decoded using multivariate data analysis. From the inner product of the reference and prediction vectors, a correlation map comparing 396 900 copolymer pairs (630 x 630) was generated. In 100% of the cases, the highest correlation was obtained for polymer pairs in which the reference and prediction vectors correspond to copolymers prepared from identical styrene monomers, thus demonstrating the high reliability of this encoding strategy. We have also established that the spectroscopic barcodes generated from the Raman and infrared spectra are independent of the copolymers' morphology (beaded versus bulk polymers). Besides the demonstration of the generality of the polymer barcoding strategy, the analytical methods developed here could in principle be extended to the investigation of the composition and purity of any other synthetic polymer and biopolymer library, or even scaffold-based combinatorial libraries.

Establishment of hepatitis A vaccine (inactivated, non-adsorbed) BRP batches 2 and 3.

PubMed

Morgeaux, S; Manniam, I; Variot, P; Buchheit, K H; Daas, A; Wierer, M; Costanzo, A

2015-01-01

The current hepatitis A vaccine (HAV), inactivated, non-adsorbed, European Pharmacopoeia (Ph. Eur.) Biological Reference Preparation (BRP) is used for the in vitro potency assay of HAV as prescribed by the Ph. Eur. general chapter 2.7.14 Assay of hepatitis A vaccine. This reference preparation was calibrated in 2008 through an international collaborative study and was assigned a potency of 12 IU/mL. During use of this BRP it appeared to be inapplicable in certain cases due to a low nominal antigen content. Consequently, the European Directorate for the Quality of Medicines and HealthCare (EDQM) established replacement batches for this BRP, calibrated against the 1(st) WHO International Standard (IS) for HAV (inactivated), using the standard in vitro ELISA (enzyme-linked immunosorbent assay) method validated previously. The results of the study showed that the candidate BRPs were suitable for the intended purpose, and following completion of the study, they were adopted in November 2014 by the Ph. Eur. Commission as HAV (inactivated, non-adsorbed) BRP batches 2 and 3, with an assigned potency of 1350 IU/mL, for in vitro antigen content determination by ELISA. As the amount of material in each vial largely exceeds the amount required for the performance of a single assay, the BRPs are to be aliquoted by users as single-use aliquots and refrozen below -50 °C prior to their use as reference preparations.

Interoperability Gap Challenges for Learning Object Repositories & Learning Management Systems

ERIC Educational Resources Information Center

Mason, Robert T.

2011-01-01

An interoperability gap exists between Learning Management Systems (LMSs) and Learning Object Repositories (LORs). Learning Objects (LOs) and the associated Learning Object Metadata (LOM) that is stored within LORs adhere to a variety of LOM standards. A common LOM standard found in LORs is the Sharable Content Object Reference Model (SCORM)…

The failures of root canal preparation with hand ProTaper

PubMed Central

Bătăiosu, Marilena; Diaconu, Oana; Moraru, Iren; Dăguci, C.; Ţuculină, Mihaela; Dăguci, Luminiţa; Gheorghiţă, Lelia

2012-01-01

The failures of root canal preparation are due to some anatomical deviation (canal in “C” or “S”) and some technique errors. The technique errors are usually present in canal root cleansing and shaping stage and are the result of endodontic treatment objectives deviation. Objectives: Our study was made on technique errors while preparing the canal roots with hand ProTaper. Methodology: Our study was made “in vitro” on 84 extracted teeth (molars, premolars, incisors and canines). The canal root of these teeth were cleansed and shaped with hand ProTaper by crown-down technique and canal irrigation with NaOCl(2,5%). The dental preparation control was made by X-ray. Results: During canal root preparation some failures were observed like: canal root overinstrumentation, zipping and stripping phenomenon, discarded and/or fractured instruments. Conclusions: Hand ProTaper represents a revolutionary progress of endodontic treatment, but a deviation from accepted rules of canal root instrumentation can lead to failures of endodontic treatment. PMID:24778848

A guide for authors of symposium papers

Treesearch

Edwin vH. Larson

1971-01-01

Suggestions for preparing a symposium paper for publication, including length, general style, manuscript format, and details of handling tables, illustrations, footnotes, literature references, etc. Also suggestions for typing.

BrainSnail: A dynamic information display system for the Sciences

PubMed Central

Telefont, Martin; Asaithambi, Asai

2009-01-01

Scientific reference management has become crucial in rapidly expanding fields of biology. Many of the reference management systems currently employed are reference centric and not object/process focused. BrainSnail is a reference management/knowledge representation application that tries to bridge disconnect between subject and reference in the fields of neuropharmacology, neuroanatomy and neurophysiology. BrainSnail has been developed with considering both individual researcher and research group efforts. PMID:19293992

Simultaneously Discovering and Localizing Common Objects in Wild Images.

PubMed

Wang, Zhenzhen; Yuan, Junsong

2018-09-01

Motivated by the recent success of supervised and weakly supervised common object discovery, in this paper, we move forward one step further to tackle common object discovery in a fully unsupervised way. Generally, object co-localization aims at simultaneously localizing objects of the same class across a group of images. Traditional object localization/detection usually trains specific object detectors which require bounding box annotations of object instances, or at least image-level labels to indicate the presence/absence of objects in an image. Given a collection of images without any annotations, our proposed fully unsupervised method is to simultaneously discover images that contain common objects and also localize common objects in corresponding images. Without requiring to know the total number of common objects, we formulate this unsupervised object discovery as a sub-graph mining problem from a weighted graph of object proposals, where nodes correspond to object proposals, and edges represent the similarities between neighbouring proposals. The positive images and common objects are jointly discovered by finding sub-graphs of strongly connected nodes, with each sub-graph capturing one object pattern. The optimization problem can be efficiently solved by our proposed maximal-flow-based algorithm. Instead of assuming that each image contains only one common object, our proposed solution can better address wild images where each image may contain multiple common objects or even no common object. Moreover, our proposed method can be easily tailored to the task of image retrieval in which the nodes correspond to the similarity between query and reference images. Extensive experiments on PASCAL VOC 2007 and Object Discovery data sets demonstrate that even without any supervision, our approach can discover/localize common objects of various classes in the presence of scale, view point, appearance variation, and partial occlusions. We also conduct broad experiments on image retrieval benchmarks, Holidays and Oxford5k data sets, to show that our proposed method, which considers both the similarity between query and reference images and also similarities among reference images, can help to improve the retrieval results significantly.

Performance Optimizing Multi-Objective Adaptive Control with Time-Varying Model Reference Modification

NASA Technical Reports Server (NTRS)

Nguyen, Nhan T.; Hashemi, Kelley E.; Yucelen, Tansel; Arabi, Ehsan

2017-01-01

This paper presents a new adaptive control approach that involves a performance optimization objective. The problem is cast as a multi-objective optimal control. The control synthesis involves the design of a performance optimizing controller from a subset of control inputs. The effect of the performance optimizing controller is to introduce an uncertainty into the system that can degrade tracking of the reference model. An adaptive controller from the remaining control inputs is designed to reduce the effect of the uncertainty while maintaining a notion of performance optimization in the adaptive control system.

Optical calculation of correlation filters for a robotic vision system

NASA Technical Reports Server (NTRS)

Knopp, Jerome

1989-01-01

A method is presented for designing optical correlation filters based on measuring three intensity patterns: the Fourier transform of a filter object, a reference wave and the interference pattern produced by the sum of the object transform and the reference. The method can produce a filter that is well matched to both the object, its transforming optical system and the spatial light modulator used in the correlator input plane. A computer simulation was presented to demonstrate the approach for the special case of a conventional binary phase-only filter. The simulation produced a workable filter with a sharp correlation peak.

Developmental differences in the naming of contextually non-categorical objects.

PubMed

Ozcan, Mehmet

2012-02-01

This study investigates the naming process of contextually non-categorical objects in children from 3 to 9 plus 13-year-olds. 112 children participated in the study. Children were asked to narrate a story individually while looking at Mercer Mayer's textless, picture book Frog, where are you? The narratives were audio recorded and transcribed. Texts were analyzed to find out how children at different ages name contextually non-categorical objects, tree and its parts in this case. Our findings revealed that increasing age in children is a positive factor in naming objects that are parts or extended forms of an object which itself constitutes a basic category in a certain context. Younger children used categorical names more frequently to refer to parts or disfigured forms of the object than older children and adults while older children and adults used specified names to refer to the parts or extended forms of the categorical names.

Spatial-Heterodyne Interferometry For Reflection And Transm Ission (Shirt) Measurements

DOEpatents

Hanson, Gregory R [Clinton, TN; Bingham, Philip R [Knoxville, TN; Tobin, Ken W [Harriman, TN

2006-02-14

Systems and methods are described for spatial-heterodyne interferometry for reflection and transmission (SHIRT) measurements. A method includes digitally recording a first spatially-heterodyned hologram using a first reference beam and a first object beam; digitally recording a second spatially-heterodyned hologram using a second reference beam and a second object beam; Fourier analyzing the digitally recorded first spatially-heterodyned hologram to define a first analyzed image; Fourier analyzing the digitally recorded second spatially-heterodyned hologram to define a second analyzed image; digitally filtering the first analyzed image to define a first result; and digitally filtering the second analyzed image to define a second result; performing a first inverse Fourier transform on the first result, and performing a second inverse Fourier transform on the second result. The first object beam is transmitted through an object that is at least partially translucent, and the second object beam is reflected from the object.

The effect of implied orientation derived from verbal context on picture recognition.

PubMed

Stanfield, R A; Zwaan, R A

2001-03-01

Perceptual symbol systems assume an analogue relationship between a symbol and its referent, whereas amodal symbol systems assume an arbitrary relationship between a symbol and its referent. According to perceptual symbol theories, the complete representation of an object, called a simulation, should reflect physical characteristics of the object. Amodal theories, in contrast, do not make this prediction. We tested the hypothesis, derived from perceptual symbol theories, that people mentally represent the orientation of an object implied by a verbal description. Orientation (vertical-horizontal) was manipulated by having participants read a sentence that implicitly suggested a particular orientation for an object. Then recognition latencies to pictures of the object in each of the two orientations were measured. Pictures matching the orientation of the object implied by the sentence were responded to faster than pictures that did not match the orientation. This finding is interpreted as offering support for theories positing perceptual symbol systems.

Effects of object asymmetry on visual attention.

PubMed

Maguire, Anne M; Bates, Timothy C; Boycott, Noël; Corballis, Michael C

2002-01-01

Unilateral neglect has been demonstrated relative to the intrinsic left side of objects, even when presented in the preserved hemispace. These results have been interpreted as evidence of an object-centered reference frame. In the present study, neurologically normal individuals were presented with letter stimuli having distinguishing features to the right (R) or left (J) of their intrinsic midline, shown in normal and mirror parity, and in six angle rotations. RTs confirmed that participants rotated the letters to the upright to decide parity: such rotation would align the object-centered and viewer-centered frames of reference, suggesting that not controlling for mental rotation would confound this effect. In addition, a dot, presented lateral to the main letter stimulus, resulted in quicker parity decisions when on the maximally-informative side of the letter. Together, the results suggest that apparent object-centered neglect may arise from the combined effects of mental rotation and within-object information asymmetries.

Cooperative multisensor system for real-time face detection and tracking in uncontrolled conditions

NASA Astrophysics Data System (ADS)

Marchesotti, Luca; Piva, Stefano; Turolla, Andrea; Minetti, Deborah; Regazzoni, Carlo S.

2005-03-01

The presented work describes an innovative architecture for multi-sensor distributed video surveillance applications. The aim of the system is to track moving objects in outdoor environments with a cooperative strategy exploiting two video cameras. The system also exhibits the capacity of focusing its attention on the faces of detected pedestrians collecting snapshot frames of face images, by segmenting and tracking them over time at different resolution. The system is designed to employ two video cameras in a cooperative client/server structure: the first camera monitors the entire area of interest and detects the moving objects using change detection techniques. The detected objects are tracked over time and their position is indicated on a map representing the monitored area. The objects" coordinates are sent to the server sensor in order to point its zooming optics towards the moving object. The second camera tracks the objects at high resolution. As well as the client camera, this sensor is calibrated and the position of the object detected on the image plane reference system is translated in its coordinates referred to the same area map. In the map common reference system, data fusion techniques are applied to achieve a more precise and robust estimation of the objects" track and to perform face detection and tracking. The work novelties and strength reside in the cooperative multi-sensor approach, in the high resolution long distance tracking and in the automatic collection of biometric data such as a person face clip for recognition purposes.

Food preparation by young adults is associated with better diet quality.

PubMed

Larson, Nicole I; Perry, Cheryl L; Story, Mary; Neumark-Sztainer, Dianne

2006-12-01

To describe food-preparation behaviors, cooking skills, resources for preparing food, and associations with diet quality among young adults. Cross-sectional analyses were performed in a sample of young adults who responded to the second wave of a population-based longitudinal study. Measures pertaining to food preparation were self-reported and dietary intake was assessed by a food frequency questionnaire, both by a mailed survey. Males (n = 764) and females (n = 946) ages 18 to 23 years. Cross-tabulations and chi2 tests were used to examine associations between food preparation, skills/resources for preparing foods, and characteristics of young adults. Mixed regression models were used to generate expected probabilities of meeting the Healthy People 2010 dietary objectives according to reported behaviors and skills/resources. Food-preparation behaviors were not performed by the majority of young adults even weekly. Sex (male), race (African American), and living situation (campus housing) were significantly related to less frequent food preparation. Lower perceived adequacy of skills and resources for food preparation was related to reported race (African American or Hispanic) and student status (part-time or not in school). The most common barrier to food preparation was lack of time, reported by 36% of young adults. Young adults who reported frequent food preparation reported less frequent fast-food use and were more likely to meet dietary objectives for fat (P < 0.001), calcium (P < 0.001), fruit (P < 0.001), vegetable (P < 0.001), and whole-grain (P = 0.003) consumption. To improve dietary intake, interventions among young adults should teach skills for preparing quick and healthful meals.

Interplay Between the Object and Its Symbol: The Size-Congruency Effect

PubMed Central

Shen, Manqiong; Xie, Jiushu; Liu, Wenjuan; Lin, Wenjie; Chen, Zhuoming; Marmolejo-Ramos, Fernando; Wang, Ruiming

2016-01-01

Grounded cognition suggests that conceptual processing shares cognitive resources with perceptual processing. Hence, conceptual processing should be affected by perceptual processing, and vice versa. The current study explored the relationship between conceptual and perceptual processing of size. Within a pair of words, we manipulated the font size of each word, which was either congruent or incongruent with the actual size of the referred object. In Experiment 1a, participants compared object sizes that were referred to by word pairs. Higher accuracy was observed in the congruent condition (e.g., word pairs referring to larger objects in larger font sizes) than in the incongruent condition. This is known as the size-congruency effect. In Experiments 1b and 2, participants compared the font sizes of these word pairs. The size-congruency effect was not observed. In Experiments 3a and 3b, participants compared object and font sizes of word pairs depending on a task cue. Results showed that perceptual processing affected conceptual processing, and vice versa. This suggested that the association between conceptual and perceptual processes may be bidirectional but further modulated by semantic processing. Specifically, conceptual processing might only affect perceptual processing when semantic information is activated. The current study PMID:27512529

Cross-contamination during the preparation of frozen chickens in the kitchen.

PubMed Central

de Wit, J. C.; Broekhuizen, G.; Kampelmacher, E. H.

1979-01-01

A study was made of the extent to which frozen broilers, contaminated with indicator organisms, can cause cross-contamination in the kitchen. In 60 kitchens a number of relevant objects were sampled during the preparation of contaminated frozen broilers. The results show that cross-contamination occurred in a high proportion of the kitchens examined. In many instances the indicator organism was still present on various objects even after rinsing, 'clearing' or washing up. In view of the possible risk of a cross-contamination with Salmonella spp. the importance of instructing food preparers is emphasized. No salmonellas could be found in the sinks of the 60 kitchens examined. PMID:379210

Metabarcoding of marine nematodes – evaluation of reference datasets used in tree-based taxonomy assignment approach

PubMed Central

2016-01-01

Abstract Background Metabarcoding is becoming a common tool used to assess and compare diversity of organisms in environmental samples. Identification of OTUs is one of the critical steps in the process and several taxonomy assignment methods were proposed to accomplish this task. This publication evaluates the quality of reference datasets, alongside with several alignment and phylogeny inference methods used in one of the taxonomy assignment methods, called tree-based approach. This approach assigns anonymous OTUs to taxonomic categories based on relative placements of OTUs and reference sequences on the cladogram and support that these placements receive. New information In tree-based taxonomy assignment approach, reliable identification of anonymous OTUs is based on their placement in monophyletic and highly supported clades together with identified reference taxa. Therefore, it requires high quality reference dataset to be used. Resolution of phylogenetic trees is strongly affected by the presence of erroneous sequences as well as alignment and phylogeny inference methods used in the process. Two preparation steps are essential for the successful application of tree-based taxonomy assignment approach. Curated collections of genetic information do include erroneous sequences. These sequences have detrimental effect on the resolution of cladograms used in tree-based approach. They must be identified and excluded from the reference dataset beforehand. Various combinations of multiple sequence alignment and phylogeny inference methods provide cladograms with different topology and bootstrap support. These combinations of methods need to be tested in order to determine the one that gives highest resolution for the particular reference dataset. Completing the above mentioned preparation steps is expected to decrease the number of unassigned OTUs and thus improve the results of the tree-based taxonomy assignment approach. PMID:27932919

Metabarcoding of marine nematodes - evaluation of reference datasets used in tree-based taxonomy assignment approach.

PubMed

Holovachov, Oleksandr

2016-01-01

Metabarcoding is becoming a common tool used to assess and compare diversity of organisms in environmental samples. Identification of OTUs is one of the critical steps in the process and several taxonomy assignment methods were proposed to accomplish this task. This publication evaluates the quality of reference datasets, alongside with several alignment and phylogeny inference methods used in one of the taxonomy assignment methods, called tree-based approach. This approach assigns anonymous OTUs to taxonomic categories based on relative placements of OTUs and reference sequences on the cladogram and support that these placements receive. In tree-based taxonomy assignment approach, reliable identification of anonymous OTUs is based on their placement in monophyletic and highly supported clades together with identified reference taxa. Therefore, it requires high quality reference dataset to be used. Resolution of phylogenetic trees is strongly affected by the presence of erroneous sequences as well as alignment and phylogeny inference methods used in the process. Two preparation steps are essential for the successful application of tree-based taxonomy assignment approach. Curated collections of genetic information do include erroneous sequences. These sequences have detrimental effect on the resolution of cladograms used in tree-based approach. They must be identified and excluded from the reference dataset beforehand.Various combinations of multiple sequence alignment and phylogeny inference methods provide cladograms with different topology and bootstrap support. These combinations of methods need to be tested in order to determine the one that gives highest resolution for the particular reference dataset.Completing the above mentioned preparation steps is expected to decrease the number of unassigned OTUs and thus improve the results of the tree-based taxonomy assignment approach.

Grasp with hand and mouth: a kinematic study on healthy subjects.

PubMed

Gentilucci, M; Benuzzi, F; Gangitano, M; Grimaldi, S

2001-10-01

Neurons involved in grasp preparation with hand and mouth were previously recorded in the premotor cortex of monkey. The aim of the present kinematic study was to determine whether a unique planning underlies the act of grasping with hand and mouth in humans as well. In a set of four experiments, healthy subjects reached and grasped with the hand an object of different size while opening the mouth (experiments 1 and 3), or extending the other forearm (experiment 4), or the fingers of the other hand (experiment 5). In a subsequent set of three experiments, subjects grasped an object of different size with the mouth, while opening the fingers of the right hand (experiments 6-8). The initial kinematics of mouth and finger opening, but not of forearm extension, was affected by the size of the grasped object congruently with the size effect on initial grasp kinematics. This effect was due neither to visual presentation of the object, without the successive grasp motor act (experiment 2) nor to synchronism between finger and mouth opening (experiments 3, 7, and 8). In experiment 9 subjects grasped with the right hand an object of different size while pronouncing a syllable printed on the target. Mouth opening and sound production were affected by the grasped object size. The results of the present study are discussed according to the notion that in an action each motor act is prepared before the beginning of the motor sequence. Double grasp preparation can be used for successive motor acts on the same object as, for example, grasping food with the hand and ingesting it after bringing it to the mouth. We speculate that the circuits involved in double grasp preparation might have been the neural substrate where hand motor patterns used as primitive communication signs were transferred to mouth articulation system. This is in accordance with the hypothesis that Broca's area derives phylogenetically from the monkey premotor area where hand movements are controlled.

21 CFR 201.313 - Estradiol labeling.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Pharmacopeia under the designation “Alpha Estradiol.” The substance should no longer be referred to in drug labeling as “Alpha Estradiol.” The Food and Drug Administration would not object to label references to the... referred to the presence of “Estradiol (formerly known as Alpha Estradiol).” ...

21 CFR 201.313 - Estradiol labeling.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Pharmacopeia under the designation “Alpha Estradiol.” The substance should no longer be referred to in drug labeling as “Alpha Estradiol.” The Food and Drug Administration would not object to label references to the... referred to the presence of “Estradiol (formerly known as Alpha Estradiol).” ...

21 CFR 201.313 - Estradiol labeling.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Pharmacopeia under the designation “Alpha Estradiol.” The substance should no longer be referred to in drug labeling as “Alpha Estradiol.” The Food and Drug Administration would not object to label references to the... referred to the presence of “Estradiol (formerly known as Alpha Estradiol).” ...

21 CFR 201.313 - Estradiol labeling.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Pharmacopeia under the designation “Alpha Estradiol.” The substance should no longer be referred to in drug labeling as “Alpha Estradiol.” The Food and Drug Administration would not object to label references to the... referred to the presence of “Estradiol (formerly known as Alpha Estradiol).” ...

21 CFR 201.313 - Estradiol labeling.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Pharmacopeia under the designation “Alpha Estradiol.” The substance should no longer be referred to in drug labeling as “Alpha Estradiol.” The Food and Drug Administration would not object to label references to the... referred to the presence of “Estradiol (formerly known as Alpha Estradiol).” ...

Advanced Food Science and Nutrition Reference Book.

ERIC Educational Resources Information Center

Texas Tech Univ., Lubbock. Home Economics Curriculum Center.

Developed with input from personnel in the industries, this reference book complements the curriculum guide for a laboratory course on the significance of nutrition in food science. The reference book is organized into 25 chapters, each beginning with essential elements and objectives. Within the text, italicized, bold-faced vocabulary terms are…

[Global patent overview of Ginkgo biloba preparation].

PubMed

Cheng, Xin-Min; Lei, Hai-Min; Liu, Wei

2013-09-01

With related global patent data as analysis samples, worldwide patent overview of Ginkgo biloba preparation is analyzed in application, applicant, technical distribution and so on. This research shows that the most important areas of G. biloba preparation are Europe and China. The European applicants start earliest along with developing smoothly, moreover, their patents have best quality. The Chinese applicants start late along with the fastest growing, and have already certain research capabilities, moreover, their patents' quality needs to be improved. This research result provides reference for development of G. biloba preparation. The author suggest that Chinese applicants learn techniques and layout experiences of other's patents fully to enhance the level of new drug development and patent protection.

[Analysis and countermeasure for quality risk in process of traditional Chinese medicine preparations].

PubMed

Yang, Ming; Yang, Yuan-Zhen; Wang, Ya-Qi; Wu, Zhen-Feng; Wang, Xue-Cheng; Luo, Jing

2017-03-01

Product quality relies on not only testing methods,but also the design and development, production control and product manufacturing all aspects of logistics management. Quality comes from the process control level.Therefore, it is very important to accurately identify the factors that may induce quality risk in the production process and quality control measures correspondingly.This article systematically analyzes the source of the quality risk of all aspects of the production process in traditional Chinese medicine preparation. Discussing ways and methods of quality risk identification of traditional Chinese medicine preparation and providing references for perfecting the whole process quality management of traditional Chinese medicine preparation. Copyright© by the Chinese Pharmaceutical Association.

[INDENA SPA company's patent portfolio of Ginkgo biloba preparation].

PubMed

Wang, Nan; Guo, Kai; Cheng, Xin-min; Liu, Wei

2015-10-01

INDENA SPA Company in Italy is a multi-national company that produces and sells plant extracts. Based on its own re- search advantages in the field of Ginkgo biloba preparation, the company protects its own products market effectively through building patent portfolio around the patents of its opponent. Based on the multi-angle analysis for patent portfolio of G. biloba preparation from the aspects of application time, legal status, technical development route, and patent portfolio layout, this article provides technical reference on research and development of G. biloba preparation, and the author suggest that Chinese applicants learn techniques and layout experiences of other patents fully to enhance the level of research and patent protection level.

Influence of strike object grounding on close lightning electric fields

NASA Astrophysics Data System (ADS)

Baba, Yoshihiro; Rakov, Vladimir A.

2008-06-01

Using the finite difference time domain (FDTD) method, we have calculated vertical electric field Ez, horizontal (radial) electric field Eh, and azimuthal magnetic field Hϕ produced on the ground surface by lightning strikes to 160-m- and a 553-m-high conical strike objects representing the Peissenberg tower (Germany) and the CN Tower (Canada), respectively. The fields were computed for a typical subsequent stroke at distances d' from the bottom of the object ranging from 5 to 100 m for the 160-m tower and from 10 to 300 m for the 553-m tower. Grounding of the 160-m object was assumed to be accomplished by its underground basement represented by a 10-m-radius and 8-m-long perfectly conducting cylinder with or without a reference ground plane located 2 m below. The reference ground plane simulates, to some extent, a higher-conducting ground layer that is expected to exist below the water table. The configuration without reference ground plane actually means that this plane is present, but is located at an infinitely large depth. Grounding of the 553-m object was modeled in a similar manner but in the absence of reference ground plane only. In all cases considered, waveforms of Eh and Hϕ are not much influenced by the presence of strike object, while waveforms of Ez are. Waveforms of Ez are essentially unipolar (as they are in the absence of strike object) when the ground conductivity σ is 10 mS/m (the equivalent transient grounding impedance is several ohms) or greater. Thus, for the CN Tower, for which σ ≥ 10 mS/m, the occurrence of Ez polarity change is highly unlikely. For the 160-m tower and for σ = 1 and 0.1 mS/m, waveforms of Ez become bipolar (exhibit polarity change) at d' ≤ 10 m and d' ≤ 50 m, respectively, regardless of the presence of the reference ground plane. The corresponding equivalent transient grounding impedances are about 30 and 50 Ω in the absence of the reference ground plane and smaller than 10 Ω in the presence of the reference ground plane. The source of opposite polarity Ez is the potential rise at the object base (at the air/ground interface) relative to the reference ground plane. For a given grounding electrode geometry, the strength of this source increases with decreasing σ, provided that the grounding impedance is linear. Potential rises at the strike object base for σ = 1 and 0.1 mS/m are some hundreds of kilovolts, which is sufficient to produce electrical breakdown from relatively sharp edges of the basement over a distance of several meters (or more) along the ground surface. The resultant ground surface arcs will serve to reduce the equivalent grounding impedance and, hence, potential rise. Therefore, the polarity change of Ez near the Peissenberg tower, for which σ is probably about 1 mS/m, should be a rare phenomenon, if it occurs at all. The equivalent transient grounding impedance of the cylindrical basement is similar to that of a hemispherical grounding electrode of the same radius. For the 160-m tower and for hemispherical grounding electrode, the transient grounding impedance is higher than its dc grounding resistance for σ = 10 and 1 mS/m, but lower for σ = 0.1 mS/m. For the 553-m tower, the transient grounding impedance of hemispherical electrode is equal to or larger than its dc resistance for all values of σ considered.

An approach to shortening the timeframe between the emergence of new compounds on the drugs market and the availability of reference standards: The microscale syntheses of nitrazolam and clonazolam for use as reference materials, utilizing polymer-supported reagents.

PubMed

Dowling, Geraldine; Kavanagh, Pierce V; Eckhardt, Hans-Georg; Twamley, Brendan; Hessman, Gary; McLaughlin, Gavin; O'Brien, John; Brandt, Simon D

2018-03-15

Nitrazolam and clonazolam are 2 designer benzodiazepines available from Internet retailers. There is growing evidence suggesting that such compounds have the potential to cause severe adverse events. Information about tolerability in humans is scarce but typically, low doses can be difficult to administer for users when handling bulk material. Variability of the active ingredient in tablet formulations can also be of a concern. Customs, toxicology and forensic laboratories are increasingly encountering designer benzodiazepines, both in tablet and powdered form. The unavailability of reference standards can impact on the ability to identify these compounds. Therefore, the need arises for exploring in-house approaches to the preparation of new psychoactive substances (NPS) that can be carried out in a timely manner. The present study was triggered when samples of clonazolam were received in powdered and tablet form at a time when reference material for this drug was commercially unavailable. Therefore, microscale syntheses of clonazolam and its deschloro analog nitrazolam were developed utilizing polymer-supported reagents starting from 2-amino-2'-chloro-5-nitrobenzophenone (clonazolam) and 2-amino-5-nitrobenzophenone (nitrazolam). The final reaction step forming the 1,2,4-triazole ring moiety was performed within a gas chromatography-mass spectrometry (GC-MS) injector. A comparison with a preparative scale synthesis of both benzodiazepine derivatives showed that microscale synthesis might be an attractive option for a forensic laboratory in terms of time and cost savings when compared with traditional methods of synthesis and when qualitative identifications are needed to direct forensic casework. The reaction by-product profiles for both the micro and the preparative scale syntheses are also presented. Copyright © 2018 John Wiley & Sons, Ltd.

Educator Preparation Reform Act

THOMAS, 113th Congress

Rep. Honda, Michael M. [D-CA-17

2013-05-23

House - 07/08/2013 Referred to the Subcommittee on Early Childhood, Elementary, and Secondary Education. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

Microscopic Procedures for Plant Meiosis.

ERIC Educational Resources Information Center

Braselton, James P.

1997-01-01

Describes laboratory techniques designed to familiarize students with meiosis and how microscopic preparations of meiosis are made. These techniques require the use of fresh or fixed flowers. Contains 18 references. (DDR)

Coordination of multiple robot arms

NASA Technical Reports Server (NTRS)

Barker, L. K.; Soloway, D.

1987-01-01

Kinematic resolved-rate control from one robot arm is extended to the coordinated control of multiple robot arms in the movement of an object. The structure supports the general movement of one axis system (moving reference frame) with respect to another axis system (control reference frame) by one or more robot arms. The grippers of the robot arms do not have to be parallel or at any pre-disposed positions on the object. For multiarm control, the operator chooses the same moving and control reference frames for each of the robot arms. Consequently, each arm then moves as though it were carrying out the commanded motions by itself.

Dynamic-gravimetric preparation of metrologically traceable primary calibration standards for halogenated greenhouse gases

NASA Astrophysics Data System (ADS)

Guillevic, Myriam; Vollmer, Martin K.; Wyss, Simon A.; Leuenberger, Daiana; Ackermann, Andreas; Pascale, Céline; Niederhauser, Bernhard; Reimann, Stefan

2018-06-01

For many years, the comparability of measurements obtained with various instruments within a global-scale air quality monitoring network has been ensured by anchoring all results to a unique suite of reference gas mixtures, also called a primary calibration scale. Such suites of reference gas mixtures are usually prepared and then stored over decades in pressurised cylinders by a designated laboratory. For the halogenated gases which have been measured over the last 40 years, this anchoring method is highly relevant as measurement reproducibility is currently much better ( < 1 %, k = 2 or 95 % confidence interval) than the expanded uncertainty of a reference gas mixture (usually > 2 %). Meanwhile, newly emitted halogenated gases are already measured in the atmosphere at pmol mol-1 levels, while still lacking an established reference standard. For compounds prone to adsorption on material surfaces, it is difficult to evaluate mixture stability and thus variations in the molar fractions over time in cylinders at pmol mol-1 levels.To support atmospheric monitoring of halogenated gases, we create new primary calibration scales for SF6 (sulfur hexafluoride), HFC-125 (pentafluoroethane), HFO-1234yf (or HFC-1234yf, 2,3,3,3-tetrafluoroprop-1-ene), HCFC-132b (1,2-dichloro-1,1-difluoroethane) and CFC-13 (chlorotrifluoromethane). The preparation method, newly applied to halocarbons, is dynamic and gravimetric: it is based on the permeation principle followed by dynamic dilution and cryo-filling of the mixture in cylinders. The obtained METAS-2017 primary calibration scales are made of 11 cylinders containing these five substances at near-ambient and slightly varying molar fractions. Each prepared molar fraction is traceable to the realisation of SI units (International System of Units) and is assigned an uncertainty estimate following international guidelines (JCGM, 2008), ranging from 0.6 % for SF6 to 1.3 % (k = 2) for all other substances. The smallest uncertainty obtained for SF6 is mostly explained by the high substance purity level in the permeator and the low SF6 contamination of the matrix gas. The measured internal consistency of the suite ranges from 0.23 % for SF6 to 1.1 % for HFO-1234yf (k = 1). The expanded uncertainty after verification (i.e. measurement of the cylinders vs. each others) ranges from 1 to 2 % (k = 2).This work combines the advantages of SI-traceable reference gas mixture preparation with a calibration scale system for its use as anchor by a monitoring network. Such a combined system supports maximising compatibility within the network while linking all reference values to the SI and assigning carefully estimated uncertainties.For SF6, comparison of the METAS-2017 calibration scale with the scale prepared by SIO (Scripps Institution of Oceanography, SIO-05) shows excellent concordance, the ratio METAS-2017 / SIO-05 being 1.002. For HFC-125, the METAS-2017 calibration scale is measured as 7 % lower than SIO-14; for HFO-1234yf, it is 9 % lower than Empa-2013. No other scale for HCFC-132b was available for comparison. Finally, for CFC-13 the METAS-2017 primary calibration scale is 5 % higher than the interim calibration scale (Interim-98) that was in use within the Advanced Global Atmospheric Gases Experiment (AGAGE) network before adopting the scale established in the present work.

Elemental analysis of soils using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and laser-induced breakdown spectroscopy (LIBS) with multivariate discrimination: tape mounting as an alternative to pellets for small forensic transfer specimens.

PubMed

Jantzi, Sarah C; Almirall, José R

2014-01-01

Elemental analysis of soil is a useful application of both laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) and laser-induced breakdown spectroscopy (LIBS) in geological, agricultural, environmental, archeological, planetary, and forensic sciences. In forensic science, the question to be answered is often whether soil specimens found on objects (e.g., shoes, tires, or tools) originated from the crime scene or other location of interest. Elemental analysis of the soil from the object and the locations of interest results in a characteristic elemental profile of each specimen, consisting of the amount of each element present. Because multiple elements are measured, multivariate statistics can be used to compare the elemental profiles in order to determine whether the specimen from the object is similar to one of the locations of interest. Previous work involved milling and pressing 0.5 g of soil into pellets before analysis using LA-ICP-MS and LIBS. However, forensic examiners prefer techniques that require smaller samples, are less time consuming, and are less destructive, allowing for future analysis by other techniques. An alternative sample introduction method was developed to meet these needs while still providing quantitative results suitable for multivariate comparisons. The tape-mounting method involved deposition of a thin layer of soil onto double-sided adhesive tape. A comparison of tape-mounting and pellet method performance is reported for both LA-ICP-MS and LIBS. Calibration standards and reference materials, prepared using the tape method, were analyzed by LA-ICP-MS and LIBS. As with the pellet method, linear calibration curves were achieved with the tape method, as well as good precision and low bias. Soil specimens from Miami-Dade County were prepared by both the pellet and tape methods and analyzed by LA-ICP-MS and LIBS. Principal components analysis and linear discriminant analysis were applied to the multivariate data. Results from both the tape method and the pellet method were nearly identical, with clear groupings and correct classification rates of >94%.

Sexism in School Textbooks Prepared under Education Reform in Turkey

ERIC Educational Resources Information Center

Esen, Yasemin

2007-01-01

The objective of this study is to analyze the new textbooks prepared under the framework of the "curriculum reform" realized in Turkey , as part of the EU harmonization process, in terms of gender representation. For this purpose, illustrations in the new ABC, Life Studies and Social Studies textbooks prepared under the new program were…

Investigating Differences in Personality Traits and Academic Needs among Prepared and Underprepared First-Year College Students

ERIC Educational Resources Information Center

Melzer, Dawn K.; Grant, Ruth M.

2016-01-01

Research has discovered that underprepared students are more likely to exhibit an external locus of control and low self-efficacy than those considered prepared. What differences exist between prepared and underprepared college students that may account for the variation in college performance? The objective of this study was to explore…

A Comparative Study of Leadership Preparation Programs in Gama (Brazil) and the United States

ERIC Educational Resources Information Center

Borges-Gatewood, Mara Rubia Fonseca; McNeal, Larry

2013-01-01

The objective of the study was to determine the relationship, if any, between leadership preparation programs types and how well school administrators are prepared to set a widely shared vision, develop a school culture, effectively manage school operations and resources, collaborate with faculty and community members, act with integrity and…

Preparation for Instruction. A Module of Instruction in Teacher Education. Prepared for Project RAFT.

ERIC Educational Resources Information Center

Handley, Herbert M., Ed.

This module, developed by the Research Applications for Teaching (RAFT) project, was written to assist students to write lesson plans that are effective and interactive. Students are given directions for the preparation of behavioral objectives and for the selection of appropriate instructional methodologies to meet the widely varying needs of…

Distance-Dependent Processing of Pictures and Words

ERIC Educational Resources Information Center

Amit, Elinor; Algom, Daniel; Trope, Yaacov

2009-01-01

A series of 8 experiments investigated the association between pictorial and verbal representations and the psychological distance of the referent objects from the observer. The results showed that people better process pictures that represent proximal objects and words that represent distal objects than pictures that represent distal objects and…

Design, Development, and Validation of Learning Objects

ERIC Educational Resources Information Center

Nugent, Gwen; Soh, Leen-Kiat; Samal, Ashok

2006-01-01

A learning object is a small, stand-alone, mediated content resource that can be reused in multiple instructional contexts. In this article, we describe our approach to design, develop, and validate Shareable Content Object Reference Model (SCORM) compliant learning objects for undergraduate computer science education. We discuss the advantages of…

26 CFR 1.6107-1 - Tax return preparer must furnish copy of return or claim for refund to taxpayer and must retain a...

Code of Federal Regulations, 2010 CFR

2010-04-01

... tax return preparer. The electronic portion of the return or claim for refund may be contained on a replica of an official form or on an unofficial form. On an unofficial form, however, data entries must reference the line numbers or descriptions on an official form. (3) For electronically filed Forms 1040EZ...

Estimation of sample size and testing power (Part 3).

PubMed

Hu, Liang-ping; Bao, Xiao-lei; Guan, Xue; Zhou, Shi-guo

2011-12-01

This article introduces the definition and sample size estimation of three special tests (namely, non-inferiority test, equivalence test and superiority test) for qualitative data with the design of one factor with two levels having a binary response variable. Non-inferiority test refers to the research design of which the objective is to verify that the efficacy of the experimental drug is not clinically inferior to that of the positive control drug. Equivalence test refers to the research design of which the objective is to verify that the experimental drug and the control drug have clinically equivalent efficacy. Superiority test refers to the research design of which the objective is to verify that the efficacy of the experimental drug is clinically superior to that of the control drug. By specific examples, this article introduces formulas of sample size estimation for the three special tests, and their SAS realization in detail.

PREPARE Act of 2014

THOMAS, 113th Congress

Rep. Cartwright, Matt [D-PA-17

2014-07-31

House - 08/01/2014 Referred to the Subcommittee on Economic Development, Public Buildings and Emergency Management. (All Actions) Tracker: This bill has the status IntroducedHere are the steps for Status of Legislation:

42 CFR 7.3 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... described in a common currency of international and national units of activity. Biological preparations means a reference biological substance which may be used for a purpose similar to that of a standard...

Future Experiments to Measure Liquid-Gas Phase Change and Heat Transfer Phenomena on the International Space Station

NASA Astrophysics Data System (ADS)

Tóth, Balázs; Development; Operations Teams, ESA's Science Management, Payload; Teams, Science; Industry, Space

2012-06-01

The article presents the approach of the European Space Agency to promote research in weightlessness and in particular onboard the International Space Station. In order to maximize the return on investments, a strong international scientific collaboration is encouraged. These Science Teams support the preparation and utilisation of the flight hardware and exploit the measurement data. In the domain of physical sciences the topics dealt with at the time of writing the present paper cover fundamental physics, fluid physics, material sciences research and specific preparatory studies in anticipation of space exploration missions. The present article focuses on two-phase (liquid-gas phase change) heat transfer related experiments. These activities cover evaporation driven thermocapillary convection, pool- and flow boiling, evaporation and condensation of films together with wettability realted issues on both reference and structured surfaces, and heat pipe systems. Some hardware are in an advanced state of development, the feasibility of some was studied or is under definition at the time of the preparation of this paper. The objectives of the experiments are described together with their expected capabilities. Beyond the understanding of mostly fundamental physical processes, the data of all the described experiments are intended to be used to validate theoretical approaches and numerical tools, which are often developed by the Science Teams in parallel with the the flight hardware design activities of space industry.

[Preparation of monoclonal antibody against 4-amylphenol and homology modeling of its Fv fragment].

PubMed

Cheng, Lei; Wu, Haizhen; Fei, Jing; Zhang, Lujia; Ye, Jiang; Zhang, Huizhan

2017-03-01

Objective To prepare and characterize a monoclonal antibody (mAb) against 4-amylphenol (4-AP), clone its cDNA sequence and make homology modeling for its Fv fragment. Methods A high-affinity anti-4-AP mAb was generated from a hybridoma cell line F10 using electrofusion between splenocytes from APA-BSA-immunized mouse and Sp2/0 myeloma cells. Then we extracted the mRNA of F10 cells and cloned the cDNA of mAb. The homology modeling and molecular docking of its Fv fragment was conducted with biological software. Results Under the optimum conditions, the ic-ELISA equation was y=A 2 +(A 1 -A 2 )/(1+(x/x 0 ) p ) (A 1 =1.28; A 2 =-0.066; x 0 =12560.75; p=0.74) with a correlation coefficient (R 2 ) of 0.997. The lowest detectable limit was 0.65 μg/mL. The heavy and light chains of mAb respectively belonged to IgG1 and Kappa. The homology modeling and molecular docking studies revealed that the binding of 4-Ap and mAb was attributed to the hydrogen bond and hydrophobic interactions. Conclusion The study successfully established a stable 4-AP mAb-secreting hybridoma cell line. The study on spatial structure of Fv fragment using homology modeling provided a reference for the development and design of single chain variable fragments.

Operations analysis for lunar surface construction: Results of two office of exploration case studies

NASA Astrophysics Data System (ADS)

Bell, Lisa Y.; Boles, Walter; Smith, Alvin

1991-08-01

In an environment of intense competition for Federal funding, the U.S. space research community is responsible for developing a feasible, cost-effective approach to establishing a surface base on the moon to fulfill long-term Government objectives. This report presents the results of a construction operations analysis of two lunar scenarios provided by the National Aeronautics and Space Administration (NASA). Activities necessary to install the lunar base surface elements are defined and scheduled, based on the productivities and availability of the base resources allocated to the projects depicted in each scenario. The only construction project in which the required project milestones were not completed within the nominal timeframe was the initial startup phase of NASA's FY89 Lunar Evolution Case Study (LECS), primarily because this scenario did not include any Earth-based telerobotic site preparation before the arrival of the first crew. The other scenario analyzed. Reference Mission A from NASA's 90-Day Study of the Human Exploration of the Moon and Mars, did use telerobotic site preparation before the manned phase of the base construction. Details of the analysis for LECS are provided, including spreadsheets indicating quantities of work and Gantt charts depicting the general schedule for the work. This level of detail is not presented for the scenario based on the 90-Day Study because many of the projects include the same (or similar) surface elements and facilities.

From Objects to Landmarks: The Function of Visual Location Information in Spatial Navigation

PubMed Central

Chan, Edgar; Baumann, Oliver; Bellgrove, Mark A.; Mattingley, Jason B.

2012-01-01

Landmarks play an important role in guiding navigational behavior. A host of studies in the last 15 years has demonstrated that environmental objects can act as landmarks for navigation in different ways. In this review, we propose a parsimonious four-part taxonomy for conceptualizing object location information during navigation. We begin by outlining object properties that appear to be important for a landmark to attain salience. We then systematically examine the different functions of objects as navigational landmarks based on previous behavioral and neuroanatomical findings in rodents and humans. Evidence is presented showing that single environmental objects can function as navigational beacons, or act as associative or orientation cues. In addition, we argue that extended surfaces or boundaries can act as landmarks by providing a frame of reference for encoding spatial information. The present review provides a concise taxonomy of the use of visual objects as landmarks in navigation and should serve as a useful reference for future research into landmark-based spatial navigation. PMID:22969737

Death Preparation of Chinese Rural Elders.

PubMed

Liu, Yanping; van Schalkwyk, Gertina J

2018-05-14

In this qualitative study, we explored how Chinese rural elders narrate death-related issues and death preparation. Adopting a phenomenological approach, we interviewed 14 participants regarding the particular actions they employ to prepare for death. The findings revealed a death preparation system for rural Chinese elders that is instrumental in how they converse about death, wish for a good death, make objects and symbols, and anticipate an afterlife as a worshiped ancestor rather than a wandering ghost. Family and family honour provide the context for death preparation. We discuss implications and the need for the death preparation education of younger generations.

DEHYDROGENATION CATALYST FOR PRODUCTION OF MTBE

EPA Science Inventory

The objectives of this project were to better understand the effect of different catalyst preparation parameters, the effect of different catalyst treatment parameters, and the mechanism of deactivation. Accordingly, catalysts were made using various preparation methods and with...

Automatic thoracic body region localization

NASA Astrophysics Data System (ADS)

Bai, PeiRui; Udupa, Jayaram K.; Tong, YuBing; Xie, ShiPeng; Torigian, Drew A.

2017-03-01

Radiological imaging and image interpretation for clinical decision making are mostly specific to each body region such as head & neck, thorax, abdomen, pelvis, and extremities. For automating image analysis and consistency of results, standardizing definitions of body regions and the various anatomic objects, tissue regions, and zones in them becomes essential. Assuming that a standardized definition of body regions is available, a fundamental early step needed in automated image and object analytics is to automatically trim the given image stack into image volumes exactly satisfying the body region definition. This paper presents a solution to this problem based on the concept of virtual landmarks and evaluates it on whole-body positron emission tomography/computed tomography (PET/CT) scans. The method first selects a (set of) reference object(s), segments it (them) roughly, and identifies virtual landmarks for the object(s). The geometric relationship between these landmarks and the boundary locations of body regions in the craniocaudal direction is then learned through a neural network regressor, and the locations are predicted. Based on low-dose unenhanced CT images of 180 near whole-body PET/CT scans (which includes 34 whole-body PET/CT scans), the mean localization error for the boundaries of superior of thorax (TS) and inferior of thorax (TI), expressed as number of slices (slice spacing ≍ 4mm)), and using either the skeleton or the pleural spaces as reference objects, is found to be 3,2 (using skeleton) and 3, 5 (using pleural spaces) respectively, or in mm 13, 10 mm (using skeleton) and 10.5, 20 mm (using pleural spaces), respectively. Improvements of this performance via optimal selection of objects and virtual landmarks and other object analytics applications are currently being pursued. and the skeleton and pleural spaces used as a reference objects

Accuracy of intraoral data acquisition in comparison to the conventional impression.

PubMed

Luthardt, R G; Loos, R; Quaas, S

2005-10-01

The achievable accuracy is a decisive parameter for the comparison of direct intraoral digitization with the conventional impression. The objective of the study was therefore to compare the accuracy of the reproduction of a model situation by intraoral digitization vs. the conventional procedure consisting of impression taking, model production, and extraoral digitization. Proceeding from a die model with a prepared tooth 16, the reference data set of the teeth 15, 16 and 17 was produced with an established procedure by means ofextraoral digitization. For the simulated intraoral data acquisition of the master model (Cerec 3D camera, Sirona, Bensheim), the camera was fastened on a stand for the measurement and the teeth digitized seven times each in defined views (occlusal, and in each case inclined by 20 degrees, from the mesio-proximal, disto-proximal, vestibular and oral aspect). Matching was automated (comparative data sets B1-B5). A clinically perfect one-step putty-and-wash impression was taken from the starting model. The model produced under defined conditions was digitized extraorally five times (digi-SCAN, comparative data sets C1-C5). The data sets B1-B5 and C1-C5 were assigned to the reference data set by means of best-fit matching and the root of the mean quadratic deviation (RMS; root mean square) calculated. The deviations were visualized, and mean positive, negative and absolute deviations calculated. The mean RMS was 27.9 microm (B1-B5) or 18.8 microm (C1-C5). The mean deviations for the prepared tooth were 18 microm/-17 microm (B1-B5) and 9 microm /-9 microm (C1-C5). For tooth 15, the mean deviations were 22 microm/-19 microm (B1-B5) and 15 microm/-16 microm (C1-C5). The intraoral method showed good results with deviations from the CAD starting model of approx. 17 microm, related to the prepared tooth 16. On the whole, in this in-vitro study, extraoral digitization with impression taking and model production showed higher accuracy than intraoral digitization. Since the inaccuracies in the conventional impression under real clinical conditions may be higher than the values determined above, a comparison under clinical conditions should be performed subsequently.

Operation of pneumococcal polysaccharide radioimmunoassay reference laboratory: coordination of the serological aspects of otitis media field trials. Annual report 28 Jun 77--27 Jun 78

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schiffman, G.

1978-04-03

The contract supports a serologic reference laboratory for the performance of radioimmunoassay of antibodies to pneumococcal polysaccharides. Antibody assays have been performed for a number of investigators studying the response of humans to pneumococcal vaccines. In addition, a large quantity of labeled polysaccharides for use in the assay have been prepared and stored.

Guide to Reference Sources on Africa, Asia, Latin America and the Caribbean, Middle East and North Africa, and Russia and East Europe: Selected and Annotated.

ERIC Educational Resources Information Center

Kennedy, James R., Jr.; And Others

This selected annotated bibliography of reference sources is designed to help college students prepare for the future by identifying critical sources on the societies and cultures of most of the world's people who have long been neglected in higher education. Encyclopedias, handbooks, and yearbooks are listed first under each area. Next are the…

The development of a computer assisted instruction and assessment system in pharmacology.

PubMed

Madsen, B W; Bell, R C

1977-01-01

We describe the construction of a computer based system for instruction and assessment in pharmacology, utilizing a large bank of multiple choice questions. Items were collected from many sources, edited and coded for student suitability, topic, taxonomy and difficulty and text references. Students reserve a time during the day, specify the type of test desired and questions are presented randomly from the subset satisfying their criteria. Answers are scored after each question and a summary given at the end of every test; details on item performance are recorded automatically. The biggest hurdle in implementation was the assembly, review, classification and editing of items, while the programming was relatively straight-forward. A number of modifications had to be made to the initial plans and changes will undoubtedly continue with further experience. When fully operational the system will possess a number of advantages including: elimination of test preparation, editing and marking; facilitated item review opportunities; increased objectivity, feedback, flexibility and descreased anxiety in students.

Teaching for adaptive expertise in biomedical engineering ethics.

PubMed

Martin, Taylor; Rayne, Karen; Kemp, Nate J; Hart, Jack; Diller, Kenneth R

2005-04-01

This paper considers an approach to teaching ethics in bioengineering based on the How People Learn (HPL) framework. Curricula based on this framework have been effective in mathematics and science instruction from the kindergarten to the college levels. This framework is well suited to teaching bioengineering ethics because it helps learners develop "adaptive expertise". Adaptive expertise refers to the ability to use knowledge and experience in a domain to learn in unanticipated situations. It differs from routine expertise, which requires using knowledge appropriately to solve routine problems. Adaptive expertise is an important educational objective for bioengineers because the regulations and knowledge base in the discipline are likely to change significantly over the course of their careers. This study compares the performance of undergraduate bioengineering students who learned about ethics for stem cell research using the HPL method of instruction to the performance of students who learned following a standard lecture sequence. Both groups learned the factual material equally well, but the HPL group was more prepared to act adaptively when presented with a novel situation.

Acceptance and Use of Health Information Technology By Community-Dwelling Elders

PubMed Central

Fischer, Shira H; David, Daniel; Crotty, Bradley H; Dierks, Meghan; Safran, Charles

2014-01-01

Objectives With the worldwide population growing in age, information technology may help meet important needs to prepare and support patients and families for aging. We sought to explore the use and acceptance of information technology for health among the elderly by reviewing the existing literature. Methods Review of literature using PubMed and Google Scholar, references from relevant papers, and consultation with experts. Results Elderly people approach the Internet and health information technology differently than younger people, but have growing rates of adoption. Assistive technology, such as sensors or home monitors, may help ‘aging in place,' but these have not been thoroughly evaluated. Elders face many barriers to using technology for healthcare decision-making, including issues with familiarity, willingness to ask for help, trust of the technology, privacy, and design challenges. Conclusions Barriers must be addressed for these tools to be available to this growing population. Design, education, research, and policy all play roles in addressing these barriers to acceptance and use. PMID:24996581

ROTI monitoring with reference to the International LOFAR Telescope

NASA Astrophysics Data System (ADS)

Kotulak, Kacper; Froń, Adam; Krankowski, Andrzej

2017-04-01

Interferometric networks operating on relatively long baselines, such as LOFAR (approx. baseline of 1500km) are one of the important scientific users of ionosphere monitoring products. Simultaneous observations of the radiosource from the different interferometric stations with such distance between can be distracted by the ionospheric medium in different ways, as signal would cross ionospheric regions with different ionization level. The main objective of presented work is to introduce ionospheric fluctuation product (ROT and ROTI maps), which will complement the main ILT dedicated product - high spatial and temporal resolution ionospheric maps (ILTG). Presented ROT/ROTI product is prepared basing on the real-time EUREF Permanent Network GNSS observations and generated with similar assumptions as ILTG products - one degree by one degree in spatial and one hour in temporal resolution. Presented product will be a part of the ILT ionospheric service planned for the nearest future. The presentation briefly presents the ROT and ROTI obtaining methodology as well as first results.

Challenges in Transgender Healthcare: The Pathology Perspective

PubMed Central

Gupta, Sarika; Imborek, Katherine L.; Krasowski, Matthew D.

2016-01-01

Background: The transgender community is one of the most marginalized sections of our society. The literature is scarce regarding the pathology and laboratory medicine challenges associated with caring for transgender patients. Objective: To summarize the available gender-transitioning options and to discuss healthcare challenges, from a pathology/laboratory medicine perspective, in the care of transgender patients. Method: We reviewed the current terminology and epidemiology relevant to the transgender population in preparing our analysis. Conclusions: The main transgender healthcare challenges in pathology/laboratory medicine practice include the inflexibility of electronic medical records in documenting affirmed gender, unfamiliarity among medical and laboratory professional with the needs of and terminology related to the transgender population, lack of reference ranges for laboratory tests, unclear guidelines regarding gender classification for blood donation eligibility criteria, and paucity of experience in handling and interpreting surgical and cytologic specimens from gender-transitioning individuals. Directed efforts to overcome these shortcomings, coupled with a more welcoming posture, are essential to achieving the highest standards of care for the transgender population. PMID:27287942

Protoplanetary Formation and the FU Orionis Outburst

NASA Technical Reports Server (NTRS)

Bodenheimer, P. H.

1996-01-01

The following three publications which reference the above grant from the NASA Origins of Solar Systems program are attached and form the final technical report for this project. The research involved comparisons of the spectral energy distributions of FU Orionis objects with theoretical models and associated studies of the structure of the outbursting accretion disks, as well as related studies on the effects of magnetic fields in disks, which will lead in the future to models of FU Orionis outbursts which include the effects of magnetic fields. The project was renewed under a new grant NAGW-4456, entitled 'Effects of FU Orionis Outbursts on Protoplanetary Disks'. Work now being prepared for publication deals more specifically with the issue of the effects of the outbursts on protoplanetary formation. Models of the spectral energy distribution of FU Orionis stars. A simple model of a buoyant magnetic dynamo in accretion disks and a numerical study of magnetic buoyancy in an accretion disk have been submitted.

Natural medicaments in dentistry

PubMed Central

Sinha, Dakshita J.; Sinha, Ashish A.

2014-01-01

The major objective in root canal treatment is to disinfect the entire root canal system. Cleaning, shaping, and use of antimicrobial medicaments are effective in reducing the bacterial load to some extent, but some bacteria do remain behind and multiply, causing reinfection. Taking into consideration the ineffectiveness, potential side-effects and safety concerns of synthetic drugs, the herbal alternatives for endodontic usage might prove to be advantageous. Over the past decade, interest in drugs derived from medicinal plants has markedly increased. Phytomedicine has been used in dentistry as anti-inflammatory, antibiotic, analgesic, sedative and also as endodontic irrigant. Herbal preparations can be derived from the root, leaves, seeds, stem, and flowers. The PubMed database search revealed that the reference list for natural medicaments featured 1480 articles and in dentistry 173 articles. A forward search was undertaken on the selected articles and author names. This review focuses on various natural drugs and products as well as their therapeutic applications when used as phytomedicine in dentistry. PMID:25558153

European union water policy--tasks for implementing "Water Framework Directive" in pre-accession countries.

PubMed

Sözen, Seval; Avcioglu, Ebru; Ozabali, Asli; Görgun, Erdem; Orhon, Derin

2003-08-01

Water Framework Directive aiming to maintain and improve the aquatic environment in the EU was launched by the European Parliament in 2000. According to this directive, control of quantity is an ancillary element in securing good water quality and therefore measures on quantity, serving the objective of ensuring good quality should also be established. Accordingly, it is a comprehensive and coordinated package that will ensure all European waters to be protected according to a common standard. Therefore, it refers to all other Directives related to water resources management such as Urban Wastewater Treatment Directive Nitrates Directive, Drinking Water Directive, Integrated Pollution Prevention Control etc. Turkey, as a candidate state targeting full-membership, should comply the necessary preparations for the implementation of the "Water Framework Directive" as soon as possible. In this study, the necessary legislative, political, institutional, and technical attempts of the pre-accession countries have been discussed and effective recommendations have been offered for future activities in Turkey.

The Physical Effects of Contact and Close-Distance Gunfire on Sweatshirt Fleece.

PubMed

Kusluski, Michael A

2018-05-01

Powder stippling caused by the impact of propellant particles during close-distance gunfire has been previously described on skin and solid objects only. Additionally, radial tearing has been described as clear evidence of a contact-distance shot, requiring no further testing. Patterns of discrete perforating holes (referred to here as "stippling perforations") and other physical damage on sweatshirt fleece fabrics were prepared. Using the firearm and ammunition in this study, stippling perforations were observed to a maximum muzzle-to-target distance of 35 cm (10 inches). In addition, radial tearing and disintegration were present (and often more extensive) at greater than contact distance. The presence of stippling perforations could augment muzzle-to-target distance estimates generated using the Griess test, or allow distance estimates when the Griess test is not feasible. Unlike what has been previously reported, testing on the original evidence (or similar substitute) is warranted when physical damage is used to estimate shooting distance. © 2017 American Academy of Forensic Sciences.

RAMONA-3B application to Browns Ferry ATWS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Slovik, G.C.; Neymotin, L.Y.; Saha, P.

1985-01-01

The Anticipated Transient Without Scram (ATWS) is known to be a dominant accident sequence for possible core melt in a Boiling Water Reactor (BWR). A recent Probabilistic Risk Assessment (PRA) analysis for the Browns Ferry nuclear power plant indicates that ATWS is the second most dominant transient for core melt in BWR/4 with Mark I containment. The most dominant sequence being the failure of long term decay heat removal function of the Residual Heat Removal (RHR) system. Of all the various ATWS scenarios, the Main Steam Isolation Valve (MSIV) closure ATWS sequence was chosen for present analysis because of itsmore » relatively high frequency of occurrence and its challenge to the residual heat removal system and containment integrity. The objective of this paper is to discuss four MSIV closure ATWS calculations using the RAMONA-3B code. The paper is a summary of a report being prepared for the USNRC Severe Accident Sequence Analysis (SASA) program which should be referred to for details. 10 refs., 20 figs., 3 tabs.« less

76 FR 26996 - Notice of Intent To Prepare an Environmental Impact Statement for New Corporate Average Fuel...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-10

...Pursuant to the National Environmental Policy Act (NEPA), NHTSA plans to prepare an Environmental Impact Statement (EIS) to analyze the potential environmental impacts of the agency's Corporate Average Fuel Economy program for passenger automobiles (referred to herein as ``passenger cars'') and non-passenger automobiles (referred to herein as ``light trucks''). The EIS will consider the potential environmental impacts of new fuel economy standards for model years 2017-2025 passenger cars and light trucks that NHTSA will be proposing pursuant to the Energy Independence and Security Act of 2007. This notice initiates the NEPA scoping process by inviting comments from Federal, State, and local agencies, Indian tribes, and the public to help identify the environmental issues and reasonable alternatives to be examined in the EIS. This notice also provides guidance for participating in the scoping process and additional information about the alternatives NHTSA expects to consider in its NEPA analysis. In preparing this notice, NHTSA has shared the document with the Council on Environmental Quality (CEQ), the Environmental Protection Agency (EPA), and the Department of Energy (DOE).

Preparation and certification of hijiki reference material, NMIJ CRM 7405-a, from the edible marine algae hijiki (Hizikia fusiforme).

PubMed

Narukawa, Tomohiro; Inagaki, Kazumi; Zhu, Yanbei; Kuroiwa, Takayoshi; Narushima, Izumi; Chiba, Koichi; Hioki, Akiharu

2012-02-01

A certified reference material, NMIJ CRM 7405-a, for the determination of trace elements and As(V) in algae was developed from the edible marine hijiki (Hizikia fusiforme) and certified by the National Metrology Institute of Japan (NMIJ), the National Institute of Advanced Industrial Science and Technology (AIST). Hijiki was collected from the Pacific coast in the Kanto area of Japan, and was washed, dried, powdered, and homogenized. The hijiki powder was placed in 400 bottles (ca. 20 g each). The concentrations of 18 trace elements and As(V) were determined by two to four independent analytical techniques, including (ID)ICP-(HR)MS, ICP-OES, GFAAS, and HPLC-ICP-MS using calibration solutions prepared from the elemental standard solution of Japan calibration service system (JCSS) and the NMIJ CRM As(V) solution, and whose concentrations are certified and SI traceable. The uncertainties of all the measurements and preparation procedures were evaluated. The values of 18 trace elements and As(V) in the CRM were certified with uncertainty (k = 2).

Evaluation of the Illumigene Malaria LAMP: A Robust Molecular Diagnostic Tool for Malaria Parasites

PubMed Central

Lucchi, Naomi W.; Gaye, Marie; Diallo, Mammadou Alpha; Goldman, Ira F.; Ljolje, Dragan; Deme, Awa Bineta; Badiane, Aida; Ndiaye, Yaye Die; Barnwell, John W.; Udhayakumar, Venkatachalam; Ndiaye, Daouda

2016-01-01

Isothermal nucleic acid amplification assays such as the loop mediated isothermal amplification (LAMP), are well suited for field use as they do not require thermal cyclers to amplify the DNA. To further facilitate the use of LAMP assays in remote settings, simpler sample preparation methods and lyophilized reagents are required. The performance of a commercial malaria LAMP assay (Illumigene Malaria LAMP) was evaluated using two sample preparation workflows (simple filtration prep (SFP)) and gravity-driven filtration prep (GFP)) and pre-dispensed lyophilized reagents. Laboratory and clinical samples were tested in a field laboratory in Senegal and the results independently confirmed in a reference laboratory in the U.S.A. The Illumigene Malaria LAMP assay was easily implemented in the clinical laboratory and gave similar results to a real-time PCR reference test with limits of detection of ≤2.0 parasites/μl depending on the sample preparation method used. This assay reliably detected Plasmodium sp. parasites in a simple low-tech format, providing a much needed alternative to the more complex molecular tests for malaria diagnosis. PMID:27827432

Terminology for contrast-enhanced sonography: a practical glossary.

PubMed

Catalano, Orlando; Migaleddu, Vincenzo; Quaia, Emilio; Caruso, Giuseppe

2007-06-01

The purpose of this glossary is to offer an updated guide to the correct terminology for contrast-enhanced sonography. This report was prepared by a panel of radiologists from the Sonography Section of the Italian Association of Medical Radiology. A leading author prepared a list of terms based on a comprehensive literature survey. The draft was analyzed by 3 experts on the topic of contrast-enhanced sonography. These reviewers reached a consensus and prepared the final version. A list of 137 terms is included. These terms are briefly defined. Their proper application is discussed, with special reference to potential misleading uses. Contrast-enhanced sonography is a relatively new diagnostic tool, now entering clinical practice in several countries. Use of appropriate, universal terminology is mandatory in the scientific setting to allow comparison between different published experiences. Additionally, use of clear, standardized terminology is necessary in the clinical setting to facilitate report understanding by the referring physician. Standardized, nonequivocal nomenclature may also help future diffusion of sonographic contrast media in countries where their application is still not approved.

Acid digestion of geological and environmental samples using open-vessel focused microwave digestion.

PubMed

Taylor, Vivien F; Toms, Andrew; Longerich, Henry P

2002-01-01

The application of open vessel focused microwave acid digestion is described for the preparation of geological and environmental samples for analysis using inductively coupled plasma-mass spectrometry (ICP-MS). The method is compared to conventional closed-vessel high pressure methods which are limited in the use of HF to break down silicates. Open-vessel acid digestion more conveniently enables the use of HF to remove Si from geological and plant samples as volatile SiF4, as well as evaporation-to-dryness and sequential acid addition during the procedure. Rock reference materials (G-2 granite, MRG-1 gabbros, SY-2 syenite, JA-1 andesite, and JB-2 and SRM-688 basalts) and plant reference materials (BCR and IAEA lichens, peach leaves, apple leaves, Durham wheat flour, and pine needles) were digested with results comparable to conventional hotplate digestion. The microwave digestion method gave poor results for granitic samples containing refractory minerals, however fusion was the preferred method of preparation for these samples. Sample preparation time was reduced from several days, using conventional hotplate digestion method, to one hour per sample using our microwave method.

A national reference for inactivated polio vaccine derived from Sabin strains in Japan.

PubMed

Shirato, Haruko; Someya, Yuichi; Ochiai, Masaki; Horiuchi, Yoshinobu; Takahashi, Motohide; Takeda, Naokazu; Wakabayashi, Kengo; Ouchi, Yasumitsu; Ota, Yoshihiro; Tano, Yoshio; Abe, Shinobu; Yamazaki, Shudo; Wakita, Takaji

2014-09-08

As one aspect of its campaign to eradicate poliomyelitis, the World Health Organization (WHO) has encouraged development of the inactivated polio vaccine (IPV) derived from the Sabin strains (sIPV) as an option for an affordable polio vaccine, especially in low-income countries. The Japan Poliomyelitis Research Institute (JPRI) inactivated three serotypes of the Sabin strains and made sIPV preparations, including serotypes 1, 2 and 3 D-antigens in the ratio of 3:100:100. The National Institute of Infectious Diseases, Japan, assessed the immunogenic stability of these sIPV preparations in a rat potency test, according to an evaluation method recommended by the WHO. The immunogenicity of the three serotypes was maintained for at least 4 years when properly stored under -70°C. Based on these data, the sIPV preparations made by JPRI have been approved as national reference vaccines by the Japanese national control authority and used for the quality control of the tetracomponent sIPV-containing diphtheria-tetanus-acellular pertussis combination vaccines that were licensed for a routine polio immunization in Japan. Copyright © 2014 Elsevier Ltd. All rights reserved.