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Sample records for preps developing survey

  1. The Continuing Development of Local Tech-Prep Initiatives.

    ERIC Educational Resources Information Center

    Silverberg, Marsha K.

    Data from national Tech-Prep surveys that were completed by more than 800 Tech-Prep consortium coordinators in fall 1993 and/or fall 1994 were analyzed to assess the emergence of Tech-Prep at the state and local levels. It was discovered that, between 1993 and 1994, the number of Tech-Prep consortia nationwide increased from 812 to 953, the…

  2. Tech Prep Intergenerational Curriculum Development Project. Final Report.

    ERIC Educational Resources Information Center

    Texas Tech Univ., Lubbock.

    A project was conducted at Texas Tech University to develop a competency-based curriculum to support statewide implementation of tech prep intergenerational programs (careers in providing services to well elderly persons and to children). Project activities included the following: (1) revision and expansion of the Intergenerational Target…

  3. Tech Prep Degree: Preparing Tomorrow's Workforce. Design, Development and Implementation of a TECH PREP Core Program. Final Report.

    ERIC Educational Resources Information Center

    Quad-City/Tri-County Vocational Regions, East Moline, IL.

    A four-stage project was undertaken to develop an exemplary tech prep core program to serve students in the Quad-City/Tri-County Vo Tech Regions school districts and Black Hawk Community College (BHCC) in Illinois. A core group planning committee consisting of education and business/industry representatives used the DACUM (Developing a Curriculum)…

  4. Tech Prep Degree: Preparing Tomorrow's Workforce. Design, Development and Implementation of a TECH PREP Core Program.

    ERIC Educational Resources Information Center

    Quad-City/Tri-County Vocational Regions, East Moline, IL.

    The focus of tech prep at Quad-City/Tri-County Vocational Regions/Black Hawk College was on providing all students with skills for higher education as well as job opportunities. To accomplish this, a comprehensive model applicable to all program areas was implemented to provide sequenced, vocationally and academically integrated, and complementary…

  5. Tech Prep Degree: Preparing Tomorrow's Workforce. Design, Development and Implementation of a TECH PREP Core Program.

    ERIC Educational Resources Information Center

    Quad-City/Tri-County Vocational Regions, East Moline, IL.

    The focus of tech prep at Quad-City/Tri-County Vocational Regions/Black Hawk College was on providing all students with skills for higher education as well as job opportunities. To accomplish this, a comprehensive model applicable to all program areas was implemented to provide sequenced, vocationally and academically integrated, and complementary…

  6. Racial Differences and Correlates of Potential Adoption of Pre-exposure Prophylaxis (PrEP): Results of a National Survey

    PubMed Central

    Wingood, Gina M.; Dunkle, Kristin; Camp, Christina; Patel, Shilpa; Painter, Julia E.; Rubtsova, Anna; DiClemente, Ralph J.

    2013-01-01

    Objective To examine the association between sociodemographic factors, sexual behaviors, and social factors on potential uptake of PrEP among African-American and White adult women in the United States. Methods Participants were recruited through a nationally representative random-digit dial telephone household survey. Participants comprised a nationally representative random sample of unmarried African-American (N=1068) and White women (N=441) aged 20–44. Interviews were conducted using computer-assisted telephone interviewing technology. Bivariate and multivariate analyses examined the relationship between sociodemographics, sexual behaviors, and social influences on women’s potential uptake of PrEP. Results In multivariate analyses, women with lower educational status, greater lifetime sexual partners, provider recommendations supportive of PrEP, and peer norms supportive of PrEP use were more likely to report potential PrEP uptake. Racial analyses revealed that compared to White women, African-American women were significantly more likely to report potential use of PrEP (aOR=1.76; p ≤ 0.001), more likely to report use PrEP if recommended by a healthcare provider (aOR=1.65; p≤0.001), less likely to report that they would be embarrassed to ask a healthcare provider for PrEP (aOR=0.59; p ≤ 0.05) and more likely to report use of PrEP if their female friends also used PrEP (aOR=2.2; p ≤ 0.001). The potential cost for PrEP was identified as a barrier to adoption by both African-American and White women. Conclusions Findings suggest that women at increased risk for HIV, including those with less education and greater number of sexual partners, may be more likely to use PrEP, although cost may serve as a barrier. PMID:23673895

  7. Development of a Career Student Guide for the Tech Prep Program for Henry County High School.

    ERIC Educational Resources Information Center

    Winchester, Ruth Ann

    This practicum report describes the research conducted in preparation for developing a career student guide to acquaint students attending Henry County High School (HCHS) in McDonough, Georgia, with the school's new tech prep program. Chapters 1 and 2 contain background information about HCHS' tech prep program and a review of literature regarding…

  8. Tech Prep Bridge Programs.

    ERIC Educational Resources Information Center

    Gohdes, William

    1995-01-01

    Although tech prep is still in its infancy in Georgia, increasing numbers of students are entering technical institutes after having completed the secondary-level component of tech prep programs. Georgia's technical institutes must begin the process of developing bridge programs to help adult students with no tech prep experience develop academic…

  9. Cytosolic Sequestration of Prep1 Influences Early Stages of T Cell Development

    PubMed Central

    Penkov, Dmitry; Palazzolo, Martina; Mondino, Anna; Blasi, Francesco

    2008-01-01

    Objective Prep1 and Pbx2 are the main homeodomain DNA-binding proteins of the TALE (three amino acid loop extension) family expressed in the thymus. We previously reported reduced Pbx2 expression and defective thymocyte maturation in Prep1 hypomorphic mice. To further investigate the role of this homeodomain DNA-binding protein in T cell development, we generated transgenic mice expressing the N-terminal fragment of Pbx1 (Pbx1NT) under the control of the Lck proximal promoter. Principal Findings Pbx1NT causes Prep1 cytosolic sequestration, abolishes Prep1-dependent DNA-binding activity and results in reduced Pbx2 expression in developing thymocytes. Transgenic thymi reveal increased numbers of CD4− CD8− CD44− (DN3 and DN4) thymocytes, due to a higher frequency of DN2 and DN4 Pbx1NT thymocytes in the S phase. Transgenic thymocytes however do not accumulate at later stages, as revealed by a normal representation of CD4/CD8 double positive and single positive thymocytes, due to a higher rate of apoptotic cell death of DN4 Pbx1NT thymocytes. Conclusion The results obtained by genetic (Prep1 hypomorphic) and functional (Pbx1NT transgenic) inactivation of Prep1 support nonredundant roles for this homeodomain protein during different stages of T cell development. PMID:18560600

  10. PrEP Awareness and Attitudes in a National Survey of Primary Care Clinicians in the United States, 2009–2015

    PubMed Central

    Stryker, Jo Ellen; Rose, Charles E.

    2016-01-01

    Objectives As trials were assessing the safety and efficacy of daily oral antiretroviral preexposure prophylaxis (PrEP) for the prevention of HIV infection, there was a clear need to understand the evolution of knowledge of, and attitudes toward, PrEP among primary care clinicians. Methods Physicians and nurse practitioners were surveyed in 2009 (n = 1500), 2010 (n = 1504), 2012 (n = 1503), 2013 (n = 1507), 2014 (n = 1508) and 2015 (n = 1501) to assess their awareness of PrEP, willingness to prescribe PrEP, and whether they support use of public funds to pay for PrEP. Pharmacists (n = 251) were surveyed about PrEP in 2012 only. Descriptive statistics were computed for physician demographics and PrEP-related questions. Prevalence ratios for willingness to prescribe PrEP were computed using Poisson regression analysis. Results Awareness of PrEP was low among clinicians (2009: 24%, 2010: 29%) but increased after trials reported effectiveness (2012: 49%, 2013: 51%, 2014: 61%, 2015: 66%). Following a description of PrEP with an estimated effectiveness of 75%, across 6 of the study years 91% of clinicians indicated a willingness to prescribe PrEP to at least one group at high risk of HIV acquisition. A smaller majority of clinicians indicated support for public funding of PrEP in 2009: 59%, 2010: 53%, and 2013: 63%. Conclusions In surveys conducted before and after the release of PrEP trial results, primary care clinicians were largely unaware of PrEP. They indicated high levels of willingness to prescribe it for patients at high risk of HIV acquisition and expressed interest in education about how to deliver this new clinical HIV prevention method. It will be important to continue monitoring clinician knowledge, attitudes, and practices as the use of PrEP increases in the US. PMID:27258374

  11. Prediction of complications in early-onset pre-eclampsia (PREP): development and external multinational validation of prognostic models.

    PubMed

    Thangaratinam, Shakila; Allotey, John; Marlin, Nadine; Dodds, Julie; Cheong-See, Fiona; von Dadelszen, Peter; Ganzevoort, Wessel; Akkermans, Joost; Kerry, Sally; Mol, Ben W; Moons, Karl G M; Riley, Richard D; Khan, Khalid S

    2017-03-30

    Unexpected clinical deterioration before 34 weeks gestation is an undesired course in early-onset pre-eclampsia. To safely prolong preterm gestation, accurate and timely prediction of complications is required. Women with confirmed early onset pre-eclampsia were recruited from 53 maternity units in the UK to a large prospective cohort study (PREP-946) for development of prognostic models for the overall risk of experiencing a complication using logistic regression (PREP-L), and for predicting the time to adverse maternal outcome using a survival model (PREP-S). External validation of the models were carried out in a multinational cohort (PIERS-634) and another cohort from the Netherlands (PETRA-216). Main outcome measures were C-statistics to summarise discrimination of the models and calibration plots and calibration slopes. A total of 169 mothers (18%) in the PREP dataset had adverse outcomes by 48 hours, and 633 (67%) by discharge. The C-statistics of the models for predicting complications by 48 hours and by discharge were 0.84 (95% CI, 0.81-0.87; PREP-S) and 0.82 (0.80-0.84; PREP-L), respectively. The PREP-S model included maternal age, gestation, medical history, systolic blood pressure, deep tendon reflexes, urine protein creatinine ratio, platelets, serum alanine amino transaminase, urea, creatinine, oxygen saturation and treatment with antihypertensives or magnesium sulfate. The PREP-L model included the above except deep tendon reflexes, serum alanine amino transaminase and creatinine. On validation in the external PIERS dataset, the reduced PREP-S model showed reasonable calibration (slope 0.80) and discrimination (C-statistic 0.75) for predicting adverse outcome by 48 hours. Reduced PREP-L model showed excellent calibration (slope: 0.93 PIERS, 0.90 PETRA) and discrimination (0.81 PIERS, 0.75 PETRA) for predicting risk by discharge in the two external datasets. PREP models can be used to obtain predictions of adverse maternal outcome risk, including

  12. Preparing for the Rollout of Pre-Exposure Prophylaxis (PrEP): A Vignette Survey to Identify Intended Sexual Behaviors among Women in Kenya and South Africa if Using PrEP

    PubMed Central

    Corneli, Amy; Field, Samuel; Namey, Emily; Agot, Kawango; Ahmed, Khatija; Odhiambo, Jacob; Skhosana, Joseph; Guest, Greg

    2015-01-01

    Introduction Several clinical trials have demonstrated the efficacy of pre-exposure prophylaxis (PrEP) in reducing HIV risk. One concern with introducing PrEP is whether users will engage in riskier sexual behaviors. Methods We assessed the effect that PrEP may have on sexual risk behaviors by administering a survey to 799 women in Bondo, Kenya, and Pretoria, South Africa. Participants were asked about their sexual behavior intentions twice — once as if they were taking PrEP and once as if they were not taking PrEP — within four risk situations (vignettes). They responded using a 5-point ordinal scale. We used a series of linear mixed effects models with an unstructured residual covariance matrix to estimate the between- and within-subject differences in the mean likelihood of engaging in risky sexual behavior across the PrEP and non-PrEP contexts. We also calculated the total percentage of participants who reported a greater likelihood of engaging in risky sexual behavior if taking PrEP than if not taking PrEP, by vignette. Results We found statistically significant differences in the mean likelihood of engaging in risky sexual behavior with the between-subject comparison (-0.17, p < 0.01) and with the within-subject comparison (-0.31, p < 0.001). Depending on the vignette, 27% to 40% of participants reported a greater likelihood of engaging in risky sexual behavior if taking PrEP than if not taking PrEP. Conclusions Our findings indicate that modest increases in risky sexual behavior could occur with PrEP. Although responses from the majority of participants suggest they would not be more likely to engage in risky sexual behavior if they took PrEP, a substantial proportion might. Programs rolling out PrEP should be prepared to assist similar women in making informed choices about reducing their risk of HIV and about their sexual health beyond HIV prevention. PMID:26056842

  13. Development and Evaluation of a Prep Course for Chemistry Graduate Teaching Assistants at a Research University

    ERIC Educational Resources Information Center

    Marbach-Ad, Gili; Schaefer, Kathryn L.; Kumi, Bryna C.; Friedman, Lee A.; Thompson, Katerina V.; Doyle, Michael P.

    2012-01-01

    This study describes the development and evaluation of a prep course for chemistry graduate teaching assistants (GTAs). The course was developed around three major goals: (i) building a community for new GTAs and socializing them into the department; (ii) modeling teaching with well-documented, innovative teaching and learning techniques; and…

  14. Summer Professional Development in Chemistry for Inservice Teachers Using OWL Quick Prep

    ERIC Educational Resources Information Center

    Powell, Cynthia B.; Pamplin, Kim L.; Blake, Robert E.; Mason, Diana S.

    2010-01-01

    Secondary teachers participating in summer professional development chemistry workshops in Texas used an online chemistry tutoring program, OWL Quick Prep (Day et al. in OWL: Online Web-based Learning, Brooks-Cole Cengage Learning, Florence, KY, 1997) as a part of the inservice training. Self-reported demographic data were used to identify factors…

  15. Summer Professional Development in Chemistry for Inservice Teachers Using OWL Quick Prep

    ERIC Educational Resources Information Center

    Powell, Cynthia B.; Pamplin, Kim L.; Blake, Robert E.; Mason, Diana S.

    2010-01-01

    Secondary teachers participating in summer professional development chemistry workshops in Texas used an online chemistry tutoring program, OWL Quick Prep (Day et al. in OWL: Online Web-based Learning, Brooks-Cole Cengage Learning, Florence, KY, 1997) as a part of the inservice training. Self-reported demographic data were used to identify factors…

  16. Assessing Tech Prep Implementation.

    ERIC Educational Resources Information Center

    Custer, Rodney L.; And Others

    1997-01-01

    Responses from 35 of 52 state tech prep coordinators indicated that 77% had evaluation plans; 68.6% had mechanisms for identifying tech prep students. Most frequent evaluation components were articulation, staff development, curriculum, and marketing. Most used evaluation criteria were job placement, postsecondary enrollment, graduation rate, and…

  17. Evaluating and Improving Tech Prep: Development, Validation, and Results of the Minnesota Self-Assessment Model.

    ERIC Educational Resources Information Center

    Pucel, David J.; And Others

    1996-01-01

    The Minnesota Tech Prep Self-Evaluation System is a framework based on ideas from Deming, Juran, and the Baldridge award. Testing with 17 Minnesota tech prep consortia found it effective in identifying areas needing improvement and promoting dialog among those involved in tech prep implementation. (SK)

  18. Summer Professional Development in Chemistry for Inservice Teachers Using OWL Quick Prep

    NASA Astrophysics Data System (ADS)

    Powell, Cynthia B.; Pamplin, Kim L.; Blake, Robert E.; Mason, Diana S.

    2010-04-01

    Secondary teachers participating in summer professional development chemistry workshops in Texas used an online chemistry tutoring program, OWL Quick Prep (Day et al. in OWL: Online Web-based Learning, Brooks-Cole Cengage Learning, Florence, KY, 1997) as a part of the inservice training. Self-reported demographic data were used to identify factors in preparation and practice that affected pretest and posttest scores. Data from the pretests and posttests indicate that nomenclature and problems requiring calculations were the most challenging topics for the cohort. The participants who correctly completed 90% of the questions in the tutoring modules showed significant improvement in content mastery.

  19. The Process of Retirement Planning Scale (PRePS): development and validation.

    PubMed

    Noone, Jack H; Stephens, Christine; Alpass, Fiona

    2010-09-01

    Although a substantial proportion of the western population is approaching retirement age, little is known about how they are preparing for the future. Much attention has been paid to the consumption of educational material and retirement wealth in the present literature, but the process of retirement planning has been ignored. S. L. Friedman and E. K. Scholnick's (1997) theoretical model provided the basis for a comprehensive measure of retirement planning. According to their process theory, individuals develop an understanding of the problem, set goals, make a decision to start preparing, and finally undertake the behaviors needed to fulfill their goals. Fifty-two items were developed to assess each stage of the planning process for financial, health, lifestyle, and psychosocial retirement planning. These were tested on a population sample of 1,449 New Zealanders aged 49-60. Confirmatory factor analysis, bivariate correlations, and hierarchical regression provided support for the valid use of the measure. Necessary antecedents, such as the tendency to look to the future, and locus of control were significantly related to the Process of Retirement Planning Scale (PRePS). The PRePS also outperformed retirement planning measures used in the Health and Retirement Study (F. T. Juster & R. Suzman, 1995) after controlling for socioeconomic and psychological variables. This measure will enable social policy makers to determine which stages of retirement planning require support and intervention. The PRePS will also help to determine which domains of retirement planning predict well-being in later life and the factors which differentiate those who are planning from those who are not.

  20. Understanding HIV Care Provider Attitudes Regarding Intentions to Prescribe PrEP

    PubMed Central

    Castel, Amanda D.; Feaster, Daniel J.; Tang, Wenze; Willis, Sarah; Jordan, Heather; Villamizar, Kira; Kharfen, Michael; Kolber, Michael A.; Rodriguez, Allan; Metsch, Lisa

    2015-01-01

    Introduction Pre-exposure prophylaxis (PrEP) is a promising approach to reducing HIV incidence. Thus garnering the support of HIV providers, who are most familiar with antiretrovirals and likely to encounter patients in HIV serodiscordant relationships, to scale-up PrEP implementation is essential. We sought to determine whether certain subgroups of HIV providers were more likely to intend to prescribe PrEP. Methods Surveys were administered to HIV providers in Miami, Florida and Washington, DC. Composite scores were developed to measure PrEP knowledge, experience, and likelihood of prescribing. Latent class analysis (LCA) was used to stratify provider attitudes toward PrEP. Results Among 142 HIV providers, 73.2% had cared for more than 20 HIV-infected patients in the prior 3 months; 17% had ever prescribed PrEP. LCA identified two classes of providers (entropy 0.904); Class 1 (n=95) found PrEP less effective and perceived barriers to prescribing it; Class 2 (n=47) perceived PrEP as moderately effective and perceived fewer barriers to prescribing it. Compared to Class 2, Class 1 had significantly less experience with PrEP delivery (t(22.7)=2.88, p=0.009) and was significantly less likely to intend to prescribe to patients with multiple sex partners (20% vs. 43%, p=0.04) and those with a drug use history (7% vs. 24%, p=0.001). Conclusions While most HIV providers found PrEP to be effective, those considering it less effective had limited knowledge and experience with PrEP and had lesser intentions to prescribe. Provider training regarding whom should receive PrEP and addressing potential barriers to PrEP provision are needed if this HIV prevention method is to be optimized. PMID:26247895

  1. Evaluation of Tech Prep System Development and Implementation in Texas Public Schools and Institutions of Higher Education. Final Report, 1994-95.

    ERIC Educational Resources Information Center

    Decision Information Resources, Inc., Houston, TX.

    In August 1993, a third-party evaluator examined tech prep system development and implementation in Texas public schools and institutions of higher education. The second year of the evaluation focused on the following aspects of Texas' tech prep system: current status of statewide implementation, secondary school counseling, professional…

  2. Ohio's Community and Technical Colleges Are Powerful Partners in Developing Tech Prep Associate Degree Programs.

    ERIC Educational Resources Information Center

    Edgar, Elaine D.; Parnell, Dale

    1996-01-01

    Reviews the implementation of the Tech Prep Associate Degree Program in Ohio. Discusses six components of the state's approach to establishing Tech Prep, the program's current status, and linkages with other state and national education reform efforts. Suggests that strong state leadership and the active participation of postsecondary institutions…

  3. Current Concepts for PrEP Adherence

    PubMed Central

    Haberer, Jessica E.

    2016-01-01

    Purpose of review This review describes 1) the current understanding of adherence to oral PrEP, 2) methods for adherence measurement, 3) approaches to supporting PrEP adherence, and 4) guidance for defining PrEP adherence goals within the larger context of HIV prevention. Recent findings PrEP adherence has generally been higher in recent trials, open-label extensions, and demonstration projects compared to the initial clinical trials; potential explanations include known PrEP efficacy and different motivations to take PrEP. Recent studies have explored adherence monitoring through electronic pill containers, short message service (SMS), and drug concentrations in hair and dried blood spots. The few PrEP adherence interventions developed to date include combinations of enhanced counseling, feedback of objective adherence measurement, and SMS. Conceptualization of PrEP adherence is evolving. The goal is not 100% adherence indefinitely, as it was in clinical trials. PrEP adherence should be defined with respect to HIV exposure, which varies over time by sexual behavior and use of other prevention strategies. Summary PrEP adherence beyond clinical trials has generally been high enough to achieve reliable HIV prevention. Future efforts to measure and support PrEP adherence should focus on the context of risk for HIV acquisition, accounting for dynamic behaviors and choices among HIV prevention options. PMID:26633638

  4. The Use of Applied Communications in Developing Critical Thinking Skills of Tech Prep Students.

    ERIC Educational Resources Information Center

    Gelven, Don R.; Stewart, Bob R.

    A study examined the effect of participation in a tech prep program, specifically an applied communications course, on the problem-solving self-appraisal and critical thinking skills of secondary students. It also explored effects of a traditional English course and an honors English course on these factors. A pretest-posttest nonequivalent…

  5. Chem-Prep PZT 95/5 for neutron generator applications : development of laboratory-scale powder processing operations.

    SciTech Connect

    Montoya, Ted V.; Moore, Roger Howard; Spindle, Thomas Lewis Jr.

    2003-12-01

    Chemical synthesis methods are being developed as a future source of PZT 95/5 powder for neutron generator voltage bar applications. Laboratory-scale powder processes were established to produce PZT billets from these powders. The interactions between calcining temperature, sintering temperature, and pore former content were studied to identify the conditions necessary to produce PZT billets of the desired density and grain size. Several binder systems and pressing aids were evaluated for producing uniform sintered billets with low open porosity. The development of these processes supported the powder synthesis efforts and enabled comparisons between different chem-prep routes.

  6. Transition from High School to College and Work for Tech Prep Participants in Eight Selected Consortia.

    ERIC Educational Resources Information Center

    Bragg, Debra D.; Loeb, Jane W.; Gong, Yuqin; Deng, Chi-Ping; Yoo, Jung-sup; Hill, Jerry L.

    The transition from high school to college and work for tech prep participants was examined in a 4-year longitudinal study of local tech prep consortia in eight regions of the United States. The study methodology drew heavily on transcript analysis and two surveys with tech prep participants and nonparticipants. The tech prep participants and…

  7. Tech Prep Newsletter, 1994.

    ERIC Educational Resources Information Center

    Everett, Jim, Ed.

    1994-01-01

    This document consists of the 36 issues of a newsletter issued during 1994. Each issue is devoted to a specific topic pertinent to Tech Prep. Tech Prep is a federally funded effort, including mathematics, sciences, and language arts, that aims to prepare students for a lifetime of learning and career advancement. The Northwest Tech Prep Consortium…

  8. Attitude towards antiretroviral Pre-Exposure Prophylaxis (PrEP) prescription among HIV specialists.

    PubMed

    Puro, Vincenzo; Palummieri, Antonio; De Carli, Gabriella; Piselli, Pierluca; Ippolito, Giuseppe

    2013-05-14

    To investigate perceptions and attitude to prescribe Pre-Exposure Prophylaxis (PrEP) among HIV specialists. A questionnaire developed through a Focus Group and literature review was administered to a convenience sample of HIV specialists during educational courses in two Regions and an online survey in February-May 2012. Participants were classified as having a positive or negative attitude according to their willingness to prescribe PrEP. Demographic and working information, experience with HIV-infected patients, information and provision of antiretrovirals to uninfected persons, self-reported knowledge, perceptions and concerns regarding PrEP were assessed. The association between a different attitude towards PrEP prescription and selected characteristics was assessed through univariate and multivariate regression analysis. Of 311 specialists, 70% would prescribe PrEP, mainly to serodiscordant partners (64%) but also to people at ongoing, high risk of HIV infection (56%); 66% advocated public support of costs. A negative attitude towards PrEP was significantly associated with lack of provision of information on, and prescription of, antiretroviral post-exposure prophylaxis; specialists with a negative attitude believed behavioural interventions to be more effective than PrEP and were more concerned about toxicity. Overall, 90% of specialists disagreed regarding a lack of time for engaging in prevention counselling and PrEP monitoring; 79% would welcome formal guidelines, while those with a negative attitude did not consider this advisable. Although conflicting attitudes appear evident, most specialists seem to be willing, with guidance from normative bodies, to promote PrEP within multiple prevention strategies among vulnerable populations. More scientific evidence regarding effectiveness could overcome resistance.

  9. Attitude towards antiretroviral pre-exposure prophylaxis (PrEP) prescription among HIV specialists

    PubMed Central

    2013-01-01

    Background To investigate perceptions and attitude to prescribe Pre-Exposure Prophylaxis (PrEP) among HIV specialists. Methods A questionnaire developed through a Focus Group and literature review was administered to a convenience sample of HIV specialists during educational courses in two Regions and an online survey in February-May 2012. Participants were classified as having a positive or negative attitude according to their willingness to prescribe PrEP. Demographic and working information, experience with HIV-infected patients, information and provision of antiretrovirals to uninfected persons, self-reported knowledge, perceptions and concerns regarding PrEP were assessed. The association between a different attitude towards PrEP prescription and selected characteristics was assessed through univariate and multivariate regression analysis. Results Of 311 specialists, 70% would prescribe PrEP, mainly to serodiscordant partners (64%) but also to people at ongoing, high risk of HIV infection (56%); 66% advocated public support of costs. A negative attitude towards PrEP was significantly associated with lack of provision of information on, and prescription of, antiretroviral post-exposure prophylaxis; specialists with a negative attitude believed behavioural interventions to be more effective than PrEP and were more concerned about toxicity. Overall, 90% of specialists disagreed regarding a lack of time for engaging in prevention counselling and PrEP monitoring; 79% would welcome formal guidelines, while those with a negative attitude did not consider this advisable. Conclusions Although conflicting attitudes appear evident, most specialists seem to be willing, with guidance from normative bodies, to promote PrEP within multiple prevention strategies among vulnerable populations. More scientific evidence regarding effectiveness could overcome resistance. PMID:23672424

  10. Developing a Web-Based Geolocated Directory of HIV Pre-Exposure Prophylaxis-Providing Clinics: The PrEP Locator Protocol and Operating Procedures.

    PubMed

    Siegler, Aaron J; Wirtz, Susan; Weber, Shannon; Sullivan, Patrick S

    2017-09-06

    Human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) is highly effective in preventing HIV transmission, yet patients interested in learning more about PrEP or in getting a PrEP prescription may not be able to find local medical providers willing to prescribe PrEP. We sought to create a national database of PrEP-providing clinics to allow for patients to have access to a unified, vetted source of PrEP providers in an easily accessible database. To develop the protocol and operating procedures for the PrEP Locator, we conducted a series of 7 key informant interviews with experts who had organized PrEP or other HIV service directories. We convened an external advisory committee and a collaborators board to gain expert and community-situated perspectives. At its public release in September 2016, the database included 1,272 PrEP-providing clinics, including clinics in all 50 states and in Puerto Rico. Web searches, referrals, and outreach to state health departments identified 58 unique lists of PrEP-providing clinics, with 33 from state health departments, 6 from government localities, 2 from professional medical organizations, and 19 from nongovernmental organizations. Out of the 2,420 clinics identified from the lists and Web searches, we removed 798 as duplicate entries, and we determined that 350 were ineligible for listing. The most common reasons for ineligibility were not having the appropriate medical licensure to prescribe PrEP (67/350) or not prescribing PrEP, based on self-report (192/350). Key informant interviews shaped important protocol decisions, such as listing clinics instead of individual clinicians as the primary data element and streamlining data collection to facilitate scalability. We developed a Web interface to provide public access to the data, with geolocated data display, search filter functionality, a webform for public suggestions of new clinics, and a publicly available directory Web tool that can be embedded in websites

  11. Planning a Tech Prep Program in Hospitality. Final Report.

    ERIC Educational Resources Information Center

    Chicago City Colleges, IL. Chicago City-Wide Coll.

    A project conducted to establish tech prep articulation training agreements between City Colleges of Chicago and several public secondary schools is described in this report. Project activities were as follows: (1) developed a handbook to define the tech prep experience and guide committee members on how tech prep can be a valuable asset to…

  12. Tech-Prep Competency Profiles within the Engineering Technologies Cluster.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains 12 competency profiles for tech prep courses within the engineering technologies cluster. The document consists of the following sections: (1) systemic curriculum reform philosophy--Ohio's vision of tech prep and its six critical components; (2) an explanation of the process of developing the tech prep competencies; (3) a…

  13. Horticulture. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Ohio State Univ., Wooster. Agricultural Technical Inst.

    This tech prep competency profile (TCP), which was developed by a consortium of Ohio educators and business/industry representatives, lists the competencies that have been identified as necessary for employment in the following occupations: nursery technician; golf course superintendent; landscape designer/manager; lawn care specialist; tree care…

  14. Tech Prep Consortia in Texas.

    ERIC Educational Resources Information Center

    Opp, Ronald D.

    The Tech Prep (TP) program is designed to provide a seamless transition for students between the high school, community college, and four-year college levels so that students can make an easier transition from school to work. In Texas, TP has developed differently from the programs of other states. Texas policy makers created a tri-agency…

  15. Horticulture. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Ohio State Univ., Wooster. Agricultural Technical Inst.

    This tech prep competency profile (TCP), which was developed by a consortium of Ohio educators and business/industry representatives, lists the competencies that have been identified as necessary for employment in the following occupations: nursery technician; golf course superintendent; landscape designer/manager; lawn care specialist; tree care…

  16. PREP for Effective Family Living.

    ERIC Educational Resources Information Center

    Welsch, Marie

    1987-01-01

    The article favorably reviews "PREP for Effective Family Living," a curriculum designed to help adolescents develop social skills and prepare for adult family life. Curriculum strengths include organization of objectives and format of the student materials. A weakness is lack of clear correlation between the student handbook and the…

  17. Adult Tech Prep.

    ERIC Educational Resources Information Center

    Schaad, Donna

    For over 2 years, Blak Hawk College (Illinois) has provided high school equivalency (GED) candidates and recipients, older returning students, and underprepared high school graduates with a Tech Prep curriculum to give them the skills to make the transition from adult basic education to college or work. The Adult Tech Prep (ATP) core curriculum…

  18. PrEP: controversy, agency and ownership

    PubMed Central

    Cairns, Gus P; Race, Kane; Goicochea, Pedro

    2016-01-01

    Pre-exposure prophylaxis (PrEP) has been and continues to be an intervention that causes controversy and debate between stakeholders involved in providing or advocating for it, and within communities in need of it. These controversies extend beyond the intrinsically complex issues of making it available. In this commentary, some of the possible roots of the air of dissent and drama that accompanies PrEP are explored. The similarities between the controversies that dogged the earliest human trials of PrEP and the ones we see today in the era of licensing and implementation are explored. We outline five mediating principles or cultural norms that may influence arguments about PrEP differently. Three areas of specific concern are identified: medical risk versus benefit, distrust and fear of healthcare interventions, and fears for individual responsibility and community cohesion. The fear that PrEP may somehow represent a loss of control over one or more of these domains is suggested as an underlying factor. The development of countervailing measures, to institute greater community “ownership” of PrEP, and concomitant improvements in the sense of individual agency over sexual risk are outlined and recommended. PMID:27760689

  19. Get on Board the Cost Effective Way: A Tech Prep Replication Process.

    ERIC Educational Resources Information Center

    Moore, Wayne A.; Szul, Linda F.; Rivosecchi, Karen

    1997-01-01

    The Northwestern Pennsylvania Tech Prep Consortium model for replicating tech prep programs includes these steps: fact finding, local industry analysis, curriculum development, detailed description, marketing strategies, implementation, and program evaluation. (SK)

  20. Tech Prep Ohio Progress Report.

    ERIC Educational Resources Information Center

    Ohio Board of Regents, Columbus.

    Tech prep programs integrate academic, occupational, and employability during the last 2 years of high school and the first 2 years of college, combining the best of college-prep academics with the best of vocational and technical education. The Ohio Tech Prep program, jointly administered by the Ohio Board of Regents and the Ohio Department of…

  1. Developing the online survey.

    PubMed

    Gordon, Jeffry S; McNew, Ryan

    2008-12-01

    Institutions of higher education are now using Internet-based technology tools to conduct surveys for data collection. Research shows that the type and quality of responses one receives with online surveys are comparable with what one receives in paper-based surveys. Data collection can take place on Web-based surveys, e-mail-based surveys, and personal digital assistants/Smartphone devices. Web surveys can be subscription templates, software packages installed on one's own server, or created from scratch using Web programming development tools. All of these approaches have their advantages and disadvantages. The survey owner must make informed decisions as to the right technology to implement. The correct choice can save hours of work in sorting, organizing, and analyzing data.

  2. Region 10 Tech Prep Consortium. Final Evaluation Report.

    ERIC Educational Resources Information Center

    Beilke, Jayne; Dacey, Vickie

    The Tech Prep Region 10 Consortium in Indiana was formed to develop and expand the use of the Tech Prep model adopted by the state to all educational institutions in the region. Involving collaboration among postsecondary institutions, secondary schools, and business and industry within state regions, the consortium design involved three phases:…

  3. Industrial Tech Prep Projects for Heartland Community College Regions. Final Project Report.

    ERIC Educational Resources Information Center

    McLean DeWitt Regional Vocational System, Bloomington, IL.

    Emphasis of the Industrial Tech Prep Projects in Heartland Community College (Illinois) regions was on planning and raising tech prep awareness among school administrators, teachers, counselors, and private industry. To develop industrial technology tech prep associate degree programs, an organizational structure was designed consisting of…

  4. Kentucky's Evaluation System for Tech Prep Programs and Data Reported by Secondary and Postsecondary Kentucky Tech Prep Programs in 1993.

    ERIC Educational Resources Information Center

    Logan, Joyce; Briscoe, Melissa

    The Kentucky Tech Prep Evaluation system was developed to establish and maintain a database and data analysis for assessment of the effectiveness of tech prep programs in achieving specific goals and in helping schools improve cognitive and noncognitive performance as reflected in the Kentucky Instructional Results Information System (KIRIS)…

  5. Tech Prep/School-to-Work Partnerships: More Trends and Challenges.

    ERIC Educational Resources Information Center

    Bragg, Debra D.; Puckett, Paula A.; Reger, William, IV; Thomas, Helen Sue; Ortman, Joan; Dornsife, Carolyn

    In 1993, 473 (55%) of the nation's 855 local tech prep consortia were surveyed regarding tech prep's goals, policies, practices, and obstacles. The 397 responding consortia (response rate, 84%) were sent follow-up surveys in 1995. Responses were obtained from 339 (85%) of the consortia. The follow-up survey revealed the following: increases in the…

  6. Healthcare Access and PrEP Continuation in San Francisco and Miami After the US PrEP Demo Project.

    PubMed

    Doblecki-Lewis, Susanne; Liu, Albert; Feaster, Daniel; Cohen, Stephanie E; Cardenas, Gabriel; Bacon, Oliver; Andrew, Erin; Kolber, Michael A

    2017-04-15

    Pre-exposure prophylaxis (PrEP) for prevention of HIV infection has demonstrated efficacy in randomized controlled trials and in demonstration projects. For PrEP implementation to result in significant reductions in HIV incidence for men who have sex with men in the United States, sufficient access to PrEP care and continued engagement outside of demonstration projects is required. We report the results of a follow-up survey of 173 former participants from the Miami and San Francisco sites of the US PrEP Demo Project, administered 4-6 months after study completion. Survey respondents continued to frequently access medical care and had a high incidence of sexually transmitted infections after completion of the Demo Project, indicating ongoing sexual risk behavior. Interest in continuing PrEP was high with 70.8% indicating that they were "very interested" in continuing PrEP. Among respondents, 39.9% reported continuation of PrEP after completion of the Demo Project, largely through their primary care providers and frequently at low or no cost. Variability in access and engagement was seen, with participants from the San Francisco site, those with medical insurance, and those with a primary care provider at the end of the Demo Project more likely to successfully obtain PrEP medication. Two respondents reported HIV seroconversion in the period between study completion and the follow-up survey. Additional effort to increase equitable access to PrEP outside of demonstration projects is needed to realize the potential impact of this evidence-based prevention intervention.

  7. The Role of Healthcare Providers in the Roll-Out of PrEP

    PubMed Central

    Krakower, Douglas S.; Mayer, Kenneth H.

    2015-01-01

    Purpose of Review To review the most recent studies assessing the preparedness of healthcare practitioners to provide anti-HIV pre-exposure prophylaxis (PrEP) and to suggest areas for future implementation research. Recent Findings As PrEP is a bio-behavioral intervention, healthcare providers are likely to play a critical role in implementing PrEP in care settings. Studies suggest that many specialized providers are aware of PrEP and support its provision as a public health intervention, though knowledge and acceptance are less among generalists. Therefore, utilization of PrEP by clinicians has been limited to a few early adopters. Concerns about the efficacy and long-term safety of PrEP, and perceived barriers to prescribing PrEP, could limit prescribing behaviors and intentions. Resistance to performing routine HIV risk assessments by clinicians is an additional barrier to implementing PrEP, though innovative tools to help clinicians routinely perform risk assessments are being developed. Summary Interventions are needed to engage a broader array of healthcare providers in PrEP provision. Utilizing a framework based on diffusion of innovation theory, this review proposes strategies that can be implemented and evaluated to increase PrEP prescribing by healthcare providers. If resources are invested in training clinicians to provide PrEP, then these stakeholders could enhance the use of PrEP as part of a prevention package by primary providers. PMID:26417953

  8. DACUM and Tech Prep: Dynamic Duo.

    ERIC Educational Resources Information Center

    Norton, Robert E.

    One significant technique for initiating needed cooperation in tech prep is through use of the DACUM (Developing a Curriculum) job analysis process. Many program directors are asking educators to identify expert workers to serve on the panel. The next phase of serious linkage and partnering occurs when the panel comes together to interact and…

  9. Tech Prep II: Implementation Final Report.

    ERIC Educational Resources Information Center

    Brown, Jane A.

    This document contains the final progress report on a tech prep implementation project and the Work Force Challenge 2000 Report developed during the project. The final report lists these major accomplishments: approximately 1,500 educators in grades K-12 were provided information concerning future global issues in the work force and the effects in…

  10. Tech Prep Program. FY 92 Report.

    ERIC Educational Resources Information Center

    Chicago City Colleges, IL. Malcolm X Coll.

    This report of the Malcolm X College Tech Prep program begins with a one-page overview of the first 4 months of funding. It describes establishment of advisory and program planning committees to plan and develop a curriculum to offer dual high school/college credit, enrollment of students from two high schools, and assessment testing of students.…

  11. Tech Prep Model for Marketing Education.

    ERIC Educational Resources Information Center

    Ruhland, Sheila K.; King, Binky M.

    A project was conducted to develop two tech prep models for marketing education (ME) in Missouri to provide a sequence of courses for skill-enhanced and time-shortened programs. First, labor market trends, employment growth projections, and business and industry labor needs in Missouri were researched and analyzed. The analysis results were used…

  12. Electronics Technology. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Lakeland Tech Prep Consortium, Kirtland, OH.

    This tech prep competency profile covers the occupation of electronics technician. Section 1 provides the occupation definition. Section 2 lists development committee members. Section 3 provides the leveling codes--abbreviations for grade level, (by the end of grade 12, by the end of associate degree), academic codes (communications, math, or…

  13. Colorado Agriculture Education Tech Prep Curriculum Guide.

    ERIC Educational Resources Information Center

    2002

    This guide is intended to provide local agricultural education tech prep programs throughout Colorado with a framework for updating their own curriculum and developing articulation with postsecondary institutions. First, a primer to standards-based education explains the role of the following items in standards-based education in agriculture: (1)…

  14. New Insights into Cooperative Binding of Homeodomain Transcription Factors PREP1 and PBX1 to DNA

    PubMed Central

    Zucchelli, Chiara; Ferrari, Elena; Blasi, Francesco; Musco, Giovanna; Bruckmann, Chiara

    2017-01-01

    PREP1 and PBX1 are homeodomain (HD) transcription factors that play crucial roles in embryonic development. Here, we present the first biophysical characterization of a PREP1 HD, and the NMR spectroscopic study of its DNA binding pocket. The data show that residues flanking the HD participate in DNA binding. The kinetic parameters for DNA binding of individual PREP1 and PBX1 HDs, and of their combination, show that isolated PREP1 and PBX1 HDs bind to DNA in a cooperative manner. A novel PREP1 motif, flanking the HD at the C-terminus, is required for cooperativity. PMID:28094776

  15. Building School-to-Work Systems on a Tech-Prep Foundation. The Status of School-to-Work Features in Tech-Prep Initiatives.

    ERIC Educational Resources Information Center

    Silverberg, Marsha K.

    Data from annual surveys of Tech-Prep consortia that were administered to all local consortia in 1993 and 1994 were analyzed to assess the implementation of key school-to-work features in 1994. Among the study's key findings were the following: Tech-Prep programs of study may help facilitate creation of career major options in school-to-work…

  16. The Tech Prep Handbook: Effective Tech Prep Policies and Practices.

    ERIC Educational Resources Information Center

    Cooper, Pamela A., Ed.; And Others

    The Strategic Planning Evaluation of Curriculum Assessment of Performance (SPECAP) project was designed by Texas Tech University to assess the implementation of programs by 25 tech prep consortia in Texas. This report describes the most effective tech prep practices discovered by SPECAP through analyses of consortia planning and implementation…

  17. Tech Prep Indiana Training Manual.

    ERIC Educational Resources Information Center

    Purdue Univ., Lafayette, IN.

    This manual is designed as a training tool for individuals who are implementing tech prep in Indiana. It is divided into three major divisions. Division I contains general information about tech prep and issues related to its implementation. Its nine chapters summarize relevant legislation, address leadership concerns, explain curriculum…

  18. Leatherwood prep plant upgrade

    SciTech Connect

    Hollis, R.W.; Jain, S.M.

    2007-06-15

    The Blue Diamond Coal Co. recently implemented major circuit modifications to the Leatherwood coal preparation plant (formerly known as the J.K. Cornett prep plant) in Slemp, KY, USA. The plant was originally built in the late 1980s, and then modified in 1999. The 2006 plant modifications included: two Krebs 33-inch heavy-media cyclones; five 10 x 20 ft single deck Conn-Weld Banana type vibrating screens; two 10 ft x 48 inch Eriez self-leveling magnetic separators; two Derrick Stacksizer high frequency screens; two CMI EBR-48 centrifugal dryers; Warman process pumps; and eight triple start MDL spiral concentrators. 2 figs.

  19. Geothermal development attitudes surveyed

    SciTech Connect

    Not Available

    1986-01-01

    The State of Hawaii has conducted several surveys on public opinion towards the development of geothermal energy. The latest poll was designed to: measure public opinion in the County of Hawaii relevant to geothermal development for electrical power supplied to Island of Hawaii residents only; measure public opinion in the County of Hawaii relevant to geothermal development of electricity to be exported for use on Oahu; and identify barriers to, and opportunities for energy conservation programs, including geothermal development. In general, the residents of the County of Hawaii favor some form of geothermal development. Issues on geothermal development of concern to the public were similar to those mentioned in the 1982 study. Basically, the issues amount to a trade-off between the economic advantages and the environmental problems of geothermal development. The strong points in favor of development include a perceived need for more energy, a strong preference for alternate energy forms over petroleum, perceived benefits for the local economy and the employment rates, and the possibility that development may reduce or contain utility bills. On the other hand, it appears that geothermal development will cause health problems for those who live near the wells, be hazardous to flora and fauna in the Puna area, and create noise and odor above tolerable levels. These are oversimplified statements of the reasons behind both support and opposition for geothermal development.

  20. Prevalence and characteristics of users of pre-exposure prophylaxis (PrEP) among men who have sex with men, San Francisco, 2014 in a cross-sectional survey: implications for disparities.

    PubMed

    Snowden, Jonathan M; Chen, Yea-Hung; McFarland, Willi; Raymond, Henry F

    2017-02-01

    Pre-exposure prophylaxis (PrEP) has gained a central role in prevention of HIV infection among men who have sex with men (MSM), particularly in San Francisco, California, USA. Programmes to enrol men in PrEP are being undertaken by a range of public and private organisations. PrEP will have the largest population impact if it reaches men who are most at risk for HIV infection, and is used in a manner that enables maximal efficacy. Access to PrEP also needs to be equitable. We report on the characteristics of men eligible for and using PrEP. Data were from the 2014 implementation of National HIV Behavioural Surveillance (NHBS) among MSM in San Francisco. NHBS uses venue-based sampling as the national standard for sampling MSM. We compare proportions of demographic characteristics of MSM using versus not using PrEP who are HIV-negative and meet Centers for Disease Control and Prevention guidelines to recommend PrEP. Overall, 64.1% of HIV-negative MSM in San Francisco would meet guidelines for PrEP use, while 9.2% of MSM overall and 14.5% of MSM eligible were using PrEP as of 2014. Men using PrEP are more likely to be white and of older age. There were no differences between men using and not using PrEP in terms of education, income and health insurance. PrEP roll-out efforts should attempt to increase reach for young, black and Hispanic MSM. Failure to equitably provide access to PrEP could exacerbate the US disparity in new HIV infections for men of colour. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  1. The Tech Prep Handbook: Essential Documents To Promte Effective Tech Prep Policies and Practices.

    ERIC Educational Resources Information Center

    Hensley, Oliver D., Ed.; And Others

    Developed during a project to document and analyze the tech prep initiative in Texas, this handbook contains exemplary documents associated with the model programs in the state. This second edition of the handbook organizes documents in sections (sections A, C, D, and G) that correspond to the major impact sectors identified during the research…

  2. High School PREP: Thematic Planning, Fall '83. Preparation for Raising Educational Performance. [HS PREP Experimental Program].

    ERIC Educational Resources Information Center

    New York City Board of Education, Brooklyn, NY. Div. of Curriculum and Instruction.

    This is a handbook designed for carrying out the goals and objectives of Preparation for Raising Educational Performance (PREP), a thematic, remedial program for ninth graders in New York City public schools. The lessons presented in the handbook model an approach to learning which follows the patterns of actual language development: listening,…

  3. The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse.

    PubMed

    Ferretti, E; Schulz, H; Talarico, D; Blasi, F; Berthelsen, J

    1999-05-01

    Human PREP1, a novel homeodomain protein of the TALE super-family, forms a stable DNA-binding complex with PBX proteins in solution, a ternary complex with PBX and HOXB1 on DNA, and is able to act as a co-activator in the transcription of PBX-HOXB1 activated promoters (Berthelsen, J., Zappavigna, V., Ferretti, E., Mavilio, F., Blasi, F. , 1998b. The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperatity. EMBO J. 17, 1434-1445; Berthelsen, J., Zappavigna, V., Mavilio, F., Blasi, F., 1998c. Prep1, a novel functional partner of Pbx proteins. EMBO J. 17, 1423-1433). Here we demonstrate the presence of DNA-binding PREP1-PBX complexes also in murine cells. In vivo, PREP1 is a predominant partner of PBX proteins in various murine tissues. However, the choice of PBX family member associated with PREP1 is largely tissue-type specific. We report the cloning and expression domain of murine Prep1 gene. Murine PREP1 shares 100% identity with human PREP1 in the homeodomain and 95% similarity throughout the whole protein. In the adult mouse, PREP1 is expressed ubiquitously, with peaks in testis and thymus. We further demonstrate the presence of murine Prep1 mRNA and protein, and of different DNA-binding PREP1-PBX complexes, in mouse embryos from at least 9.5 days p.c. Moreover, we show that PREP1 is present in all embryonic tissues from at least 7.5-17.5 days p.c with a predominantly nuclear staining. PREP1 is able to super-activate the PBX-HOXB-1 autoregulated Hoxb-1 promoter, and we show that all three proteins, PREP1, PBX and HOXB-1, are present together in the mouse rhombomere 4 domain in vivo, compatible with a role of PREP1 as a regulator of PBX and HOXB-1 proteins activity during development.

  4. Career Development Survey.

    ERIC Educational Resources Information Center

    Mulley, Barbara W.; And Others

    Based on a 1992 survey of 146 child care centers, this report documents the current wages and turnover rates for early child care staff in the St. Louis metropolitan area. The survey was designed to collect descriptive information about the population of individuals working in child care and early education and to provide baseline data to assess…

  5. PREP advertisement features affect smokers' beliefs regarding potential harm.

    PubMed

    Strasser, A A; Tang, K Z; Tuller, M D; Cappella, J N

    2008-09-01

    The Institute of Medicine report on potential reduced exposure products (PREPs) recommends that advertising and labelling be regulated to prevent explicitly or implicitly false or misleading claims. Belief that a product is less harmful may increase use or prevent smoking cessation. To determine the effect of altering advertisement features on smokers' beliefs of the harm exposure from a PREP. A Quest advertisement was digitally altered using computer software and presented to participants using web-based television recruitment contracted through a survey company. 500 current smokers completed demographic and smoking history questions, were randomised to view one of three advertisement conditions, then completed eight items assessing their beliefs of the harmfulness of the product. Advertisement conditions included the original, unaltered advertisement; a "red" condition where the cigarette packages were digitally altered to the colour red, implying increased harm potential; and a "no text" condition where all text was removed to reduce explicit product information. Polytomous logistic regression, using "incorrect," "unsure" and "correct" as outcomes, and advertisement type and covariates as predictors, was used for analyses. Participants randomised to the "no text" advertisement were less likely to be incorrect in their beliefs that Quest cigarettes are lower in tar, less addictive, less likely to cause cancer, have fewer chemicals, are healthier and make smoking safer. Smokers can form false beliefs about the harmfulness of PREP products based on how the PREPs are marketed. Careful examination must be undertaken to provide empirical evidence to better formulate regulatory principles of PREP advertising.

  6. Knowledge is Power! Increased Provider Knowledge Scores Regarding Pre-exposure Prophylaxis (PrEP) are Associated with Higher Rates of PrEP Prescription and Future Intent to Prescribe PrEP.

    PubMed

    Blumenthal, Jill; Jain, Sonia; Krakower, Douglas; Sun, Xiaoying; Young, Jason; Mayer, Kenneth; Haubrich, Richard

    2015-05-01

    The FDA approval of emtricitabine/tenofovir disoproxil fumarate for pre-exposure prophylaxis (PrEP) in 2012 has raised questions about the delivery of PrEP in a real-world setting. iPad-based questionnaires were given to providers at conferences in California and New York to assess knowledge, experience and attitudes regarding PrEP in HIV and non-HIV providers. HIV provider status was defined either by self-identification or by having greater than 5 years of HIV care experience. Knowledge scores were the sum of correct answers from five PrEP knowledge questions. Univariate analyses used t-test to compare knowledge scores and Fisher's exact test for past or future PrEP prescription between HIV and non-HIV providers. Multivariable linear or logistic regression models were used to assess factors associated with the outcomes. Of 233 respondents, the mean age was 40 years, 59 % were White, 59 % were physicians and 52 % were HIV providers. In univariate analysis, mean PrEP knowledge scores (max 5) were significantly higher for HIV providers (2.8 versus 2.2; p < 0.001), age > 41 (mean 2.8 versus 2.3; p = 0.004), White race (2.7 versus 2.2; p = 0.026) and participants in the New York region (3.0 versus 2.3; p < 0.001). In a multivariable model of knowledge scores, all but age remained significant. Among 201 potential prescribers, the rate of prior PrEP prescription was higher among HIV providers than non-HIV providers (34 versus 9 %; p < 0.001) and by knowledge score, but the association with provider status was no longer significant in multivariable analysis that controlled for knowledge. Intent to prescribe PrEP in the future was high for all provider types (64 %) and was associated with knowledge scores in multivariable analysis. The most common concerns about PrEP (>40 % of providers) were drug toxicities, development of resistance and patient adherence to follow-up; 32 % identified risk compensation as a concern. HIV providers had significantly greater PrEP knowledge

  7. Tech Prep and Educational Reform. Reprint Series.

    ERIC Educational Resources Information Center

    Hoerner, James L.

    1991-01-01

    Tech prep is a new initiative that shows great promise for educational reform. However, "tech prep" is not the new name for vocational education. Tech prep is a new program of articulated education involving 2 years of high school and 2 years of postsecondary preparation that includes a common core of mathematics, science,…

  8. Integration of Vocational and Academic Learning (Model TECH PREP Education Project). Final Performance and Financial Report.

    ERIC Educational Resources Information Center

    Richmond County School District, Rockingham, NC.

    This report describes how the Richmond County, North Carolina, Tech Prep demonstration project developed a model program with the following objectives: (1) market the Richmond Tech Prep model in every state; (2) disseminate information to at least 3,000 new persons from other states; (3) maintain assistance to previous adopters; (4) provide…

  9. Developing a disaster preparedness campaign targeting low-income Latino immigrants: focus group results for project PREP.

    PubMed

    Eisenman, David P; Glik, Deborah; Maranon, Richard; Gonzales, Lupe; Asch, Steven

    2009-05-01

    Low-income immigrant Latinos are particularly vulnerable to disasters because they are both ill-prepared and disproportionately affected. Disaster preparedness programs that are culturally appropriate must be developed and tested. To develop such a program, we conducted 12 focus groups with low-income immigrant Latinos to understand their perceptions and understanding of disaster preparedness, and facilitators and obstacles to it. Participants were concerned about remaining calm during an earthquake. Obstacles to storage of disaster supplies in a kit and developing a family communication plan were mentioned frequently. Misunderstandings were voiced about the proper quantity of water to store and about communication plans. Several focus groups spontaneously suggested small group discussions (platicas) as a way to learn about disaster preparedness. They wanted specific help with building their family communication plans. They rated promotoras de salud highly as potential teachers. Results will guide the development of a disaster preparedness program tailored to the needs of low-income Latino immigrants.

  10. NEXT GENERATION ORAL PrEP: BEYOND TENOFOVIR

    PubMed Central

    Abraham, Bisrat K.; Gulick, Roy

    2013-01-01

    Purpose Clinical trials of oral pre-exposure prophylaxis (PrEP) have focused testing on regimens of tenofovir (TDF) with or without emtricitabine (FTC). However, TDF may be associated with toxicities (renal, bone) and FTC may select for drug resistance. In this review, we discuss agents that might serve as alternatives to TDF/FTC for HIV prevention. Recent Findings Several drug characteristics are important to consider when selecting agents for PrEP with the most critical being safety, tolerability, adequate penetration into target tissues, prevention of HIV infection, and long lasting activity with convenient dosing. With these factors in mind, we review several potentially useful agents for PrEP. The first group includes drugs that are already FDA-approved (maraviroc, raltegravir) with attributes that make them attractive for PrEP. The second groups of drugs include investigational agents with long-lasting activities that are being developed in parenteral form (rilpivirine-long acting, S/GSK 1265744, ibalizumab). Summary Current research suggests there will be a broader array of PrEP drugs to choose from in the near future, thereby giving clinicians the flexibility to select agents that best suit the needs of their patient population. PMID:23032733

  11. PREPping Students for Authentic Science

    ERIC Educational Resources Information Center

    Dolan, Erin L.; Lally, David J.; Brooks, Eric; Tax, Frans E.

    2008-01-01

    In this article, the authors describe a large-scale research collaboration, the Partnership for Research and Education in Plants (PREP), which has capitalized on publicly available databases that contain massive amounts of biological information; stock centers that house and distribute inexpensive organisms with different genotypes; and the…

  12. Orion EM-1 Booster Preps - Aft Skirt Preps/Painting

    NASA Image and Video Library

    2016-10-28

    A technician with Orbital ATK, prime contractor for the Space Launch System (SLS) Booster, preps a section of the right hand aft skirt for primer and paint in a support building at the Hangar AF facility at Cape Canaveral Air Force Station in Florida. The space shuttle-era aft skirt will be used on the right hand booster of NASA's SLS rocket for Exploration Mission 1 (EM-1). NASA is preparing for EM-1, deep space missions, and the Journey to Mars.

  13. Educational Cooperatives. PREP-23

    ERIC Educational Resources Information Center

    National Center for Educational Communication (DHEW/OE), Washington, DC.

    Dr. Larry W. Hughes and Dr. C. M. Achilles of the University of Tennessee, Knoxville, conducted a national survey for the Office of Education on educational cooperatives--studying and reporting on the nature and kind of cooperative endeavors, their organization, governance, financial arrangements, services, and personnel. Their study focused upon…

  14. Rhode Island Tech Prep Business & Industry Resource Guide.

    ERIC Educational Resources Information Center

    Community Coll. of Rhode Island, Warwick.

    This guide provides educators with information about developing partnerships with businesses. It begins with a rationale for forging education-business relationships and highlights benefits to all parties--educators, businesses, and students. The Rhode Island Tech Prep Associate Degree Program is cited as an example of how to create win-win…

  15. Tech-Prep Program: Drafting/CAD Electronics.

    ERIC Educational Resources Information Center

    Northwest Suburban Career Cooperative, Palatine, IL.

    The Northwest Suburban Career Cooperative (Illinois) developed tech prep curricula for drafting/computer-aided design and electronics training program areas. Task forces selected for the two program areas identified the type of curriculum that should be provided to train future employees and the competencies needed by students successfully…

  16. Computer-Integrated Manufacturing Technology. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Lakeland Tech Prep Consortium, Kirtland, OH.

    This tech prep competency profile covers these occupations: manufacturing technician, computer-assisted design and drafting (CADD) technician, quality technician, and mechanical technician. Section 1 provides occupation definitions. Section 2 lists development committee members. Section 3 provides the leveling codes---abbreviations for grade level…

  17. A Readiness Test for Disadvantaged Preschool Children. PREP-22.

    ERIC Educational Resources Information Center

    National Center for Educational Communication (DHEW/OE), Washington, DC.

    In response to the pressing needs to develop a culture-fair, nonverbal readiness test for rural and urban disadvantaged preschool children, a special project was undertaken. PREP kit no. 22 was adapted from the final report of a project conducted by Dr. Wanda Walker, Northwest Missouri State College, Maryville, and supported by the Office of…

  18. PREP advertisement features affect smokers’ beliefs regarding potential harm

    PubMed Central

    Strasser, Andrew A; Tang, Kathy Z; Tuller, Michael D; Cappella, Joseph N

    2014-01-01

    Background The Institute of Medicine report on potential reduced exposure products (PREPs) recommends that advertising and labelling be regulated to prevent explicitly or implicitly false or misleading claims. Belief that a product is less harmful may increase use or prevent smoking cessation. Objective To determine the effect of altering advertisement features on smokers’ beliefs of the harm exposure from a PREP. Methods A Quest advertisement was digitally altered using computer software and presented to participants using web-based television recruitment contracted through a survey company. 500 current smokers completed demographic and smoking history questions, were randomised to view one of three advertisement conditions, then completed eight items assessing their beliefs of the harmfulness of the product. Advertisement conditions included the original, unaltered advertisement; a “red” condition where the cigarette packages were digitally altered to the colour red, implying increased harm potential; and a “no text” condition where all text was removed to reduce explicit product information. Polytomous logistic regression, using “incorrect,” “unsure” and “correct” as outcomes, and advertisement type and covariates as predictors, was used for analyses. Results Participants randomised to the “no text” advertisement were less likely to be incorrect in their beliefs that Quest cigarettes are lower in tar, less addictive, less likely to cause cancer, have fewer chemicals, healthier and make smoking safer. Conclusions Smokers can form false beliefs about the harmfulness of PREP products based on how the PREPs are marketed. Careful examination must be undertaken to provide empirical evidence to better formulate regulatory principles of PREP advertising. PMID:18768457

  19. Measuring Acceptability and Preferences for Implementation of Pre-Exposure Prophylaxis (PrEP) Using Conjoint Analysis: An Application to Primary HIV Prevention Among High Risk Drug Users.

    PubMed

    Shrestha, Roman; Karki, Pramila; Altice, Frederick L; Dubov, Oleksandr; Fraenkel, Liana; Huedo-Medina, Tania; Copenhaver, Michael

    2017-07-10

    Although people who use drugs (PWUD) are one of the key risk populations who could benefit from the use of pre-exposure prophylaxis (PrEP), to date, little attention has been given to incorporating PrEP into HIV prevention approaches targeting this underserved group. This study investigated the acceptability of PrEP based on a number of known PrEP attributes among high-risk PWUD in a drug treatment setting. A total of 400 HIV-negative PWUD, who reported drug- and/or sex-related risk behaviors were recruited from a methadone clinic to complete a stated preference (full-profile conjoint) survey. Participants ranked the eight hypothetical PrEP program scenarios with varied combinations of six attributes related to PrEP (cost, dosing, efficacy, side-effects, treatment setting, and frequency of HIV testing). SPSS conjoint procedure was used to estimate the relative importance of each attribute and preferences across eight possible PrEP delivery programs. PrEP acceptability ranged from 30.6 to 86.3% with a mean acceptability of 56.2% across the eight hypothetical PrEP program scenarios. The PrEP program scenario with the highest acceptability had the following attribute levels: insurance covered, daily dosing, 95% effective, no side-effects, treatment at HIV clinic, and HIV testing needed every 6 months. The cost associated with PrEP was the most important attribute (relative importance score: RIS = 38.8), followed by efficacy (RIS = 20.5) and side effects (RIS = 11.9); other attributes had no significant effect. Our findings reported a high acceptability of PrEP in response to different PrEP program scenarios with different attribute profiles. As the result of having this information, researchers and policymakers will be better equipped for evidence informed targeting and dissemination efforts to optimize PrEP uptake among this underserved population.

  20. I Knew I Would Be Safer. Experiences of Kenyan HIV Serodiscordant Couples Soon After Pre-Exposure Prophylaxis (PrEP) Initiation

    PubMed Central

    Heffron, Renee; Curran, Kathryn; Vusha, Sophie; Ngutu, Mariah; Mugo, Nelly; Celum, Connie; Baeten, Jared M.

    2016-01-01

    Abstract Pre-exposure prophylaxis (PrEP) for HIV-uninfected persons is highly efficacious for HIV prevention. Understanding how people at risk for HIV will use PrEP is important to inform PrEP scale-up and implementation. We used qualitative methods to gather insights into couples' early experiences with PrEP use within the Partners Demonstration Project, an open-label implementation study evaluating integrated delivery of PrEP and antiretroviral therapy (ART). PrEP is offered to HIV uninfected partners until the HIV-infected partner initiates and sustains ART use (i.e., PrEP as a “bridge” to ART initiation and viral suppression). From August 2013 to March 2014 we conducted 20 in-depth dyadic interviews (n = 40) with heterosexual HIV serodiscordant couples participating at the Thika, Kenya study site, exploring how couples make decisions about using PrEP for HIV prevention. We developed and applied deductive and inductive codes to identify key themes related to experiences of PrEP initiation and use of time-limited PrEP. Couples reported that PrEP offered them an additional strategy to reduce the risk of HIV transmission, meet their fertility desires, and cope with HIV serodiscordance. Remaining HIV negative at follow-up visits reinforced couples' decisions and motivated continued adherence to PrEP. In addition, confidence in their provider's advice and client-friendly services were critical to their decisions to initiate and continue use of PrEP. Strategies for wide-scale PrEP delivery for HIV serodiscordant couples in low resource settings may include building capacity of health providers to counsel on PrEP adoption while addressing couples' concerns and barriers to adoption and continued use. PMID:26836236

  1. From modeling to morals: imagining the future of HIV PREP in Lesotho.

    PubMed

    Kenworthy, Nora J; Bulled, Nicola

    2013-08-01

    Amidst growing global endorsements of new biomedical HIV prevention strategies, ARV-based pre-exposure prophylaxis (ARV PrEP) has garnered considerable attention as a potentially promising prevention strategy. Though it may offer more effective protection for certain at-risk groups than conventional prevention strategies (such as sexual partner reduction, condom use, and prevention of mother-to-child transmission), PrEP is more costly. PrEP requires more ongoing contact between individuals and providers, and a level of surveillance from the health system that is not necessary with other preventive measures. In this sense, it represents a new bio-technology for HIV prevention that poses particular challenges for worldwide implementation, given developing countries' struggling health systems and incomplete HIV treatment programs. Since the emergence of PrEP has stimulated ethical discussions premised on incomplete knowledge of efficacy and implementation, this paper explores the ethical parameters of a likely scenario for PrEP usage in a single, resource-poor country. We first develop a plausible model for PrEP deployment and utilization based on current PrEP research, while carefully considering the reigning institutional values of feasibility and effectiveness in global health approaches. Drawing on ethnographic research of HIV treatment and prevention approaches in Lesotho, we address ethical questions arising from this scenario of PrEP delivery. Lesotho presents a compelling and emblematic case study of PrEP's potential successes and pitfalls in a developing country, given the country's high HIV prevalence, struggles to achieve universal access to HIV treatment regimes, continued existence of stigma around the epidemic, and difficulties in addressing persistent social inequalities that fuel infections.

  2. Appendix B: Methodology. [2014 Teacher Prep Review

    ERIC Educational Resources Information Center

    Greenberg, Julie; Walsh, Kate; McKee, Arthur

    2014-01-01

    The "NCTQ Teacher Prep Review" evaluates the quality of programs that provide preservice preparation of public school teachers. This appendix describes the scope, methodology, timeline, staff, and standards involved in the production of "Teacher Prep Review 2014." Data collection, validation, and analysis for the report are…

  3. Health Technologies State Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This "tech prep" state competency profile contains all the competencies required and recommended for entry-level employees in occupations in the health technologies cluster. Introductory materials include the following: descriptions of the different types of competencies (essential ones that must be included in all new tech prep programs…

  4. Tech Prep Career Passports for Rewarding Futures.

    ERIC Educational Resources Information Center

    Rouse, Charles

    1995-01-01

    A Texas school system's Tech Prep Career Passport program equips high school students with skills consistent with their career goals and businesses with a better-prepared workforce. The Passport documents a graduate's completion of a three-course concentration within one of six tech-prep career pathways. A resume, letters of introduction and…

  5. Tech Prep Compendium of Models. [Revised].

    ERIC Educational Resources Information Center

    Delaware Technical and Community Coll., Dover.

    This publication discusses four models for technical preparation (tech prep): program organization; student progress; tech prep data collection and evaluation model; and school/community. The program organization model is divided into four sections. Section I, the business industry, and labor section, shows the flow from craft committee and…

  6. Tech Prep Career Passports for Rewarding Futures.

    ERIC Educational Resources Information Center

    Rouse, Charles

    1995-01-01

    A Texas school system's Tech Prep Career Passport program equips high school students with skills consistent with their career goals and businesses with a better-prepared workforce. The Passport documents a graduate's completion of a three-course concentration within one of six tech-prep career pathways. A resume, letters of introduction and…

  7. A Guide to Survey Development: Manual on Writing a Survey.

    ERIC Educational Resources Information Center

    Stacey, Susan E.; Moyer, Kerry L.

    This handbook was developed for use by individuals with limited experience in performing good survey-based research. The essential procedures in the preparation of a survey are outlined and discussed. The method of survey construction proposed consists of several tasks: (1) survey objectives and research questions are specified; (2) literature is…

  8. Microteaching. PREP-17.

    ERIC Educational Resources Information Center

    Allen, Dwight W.; Cooper, James M.

    Microteaching, a technique for training teachers to develop specific teaching skills through the use of a scaled down classroom situation, has proved to be not only effective but also strongly appealing to teachers. A state-of-the-art paper entitled "Microteaching: History and Present Status" prepared by the authors for the ERIC…

  9. Development of a Second Version of the Cobas AmpliPrep/Cobas TaqMan Hepatitis C Virus Quantitative Test with Improved Genotype Inclusivity▿

    PubMed Central

    Vermehren, Johannes; Colucci, Giuseppe; Gohl, Peter; Hamdi, Nabila; Abdelaziz, Ahmed Ihab; Karey, Ursula; Thamke, Diana; Zitzer, Heike; Zeuzem, Stefan; Sarrazin, Christoph

    2011-01-01

    Hepatitis C virus (HCV) RNA measurement has been facilitated by the introduction of real-time PCR-based assays with low limits of detection and broad dynamic ranges for quantification. In the present study, the performance of two second-version prototypes of the Cobas AmpliPrep/Cobas TaqMan HCV Quantitative Test (CAP/CTM v2) with decreased sample input volume and improved genotype inclusivity was investigated. A total of 232 serum and plasma samples derived from patients with chronic hepatitis C (genotype 1 [GT1], n = 108; GT2, n = 8; GT3, n = 24; GT4, n = 87; GT5, n = 3; and GT6, n = 2) were processed in parallel with the Cobas AmpliPrep/Cobas TaqMan HCV Test (CAP/CTM), Cobas Amplicor HCV Monitor Test v2.0 (CAM), and two second-version prototype formulations of CAP/CTM, Mastermix 1 (MMx1) and MMx2. In addition, three GT4 transcripts containing rare variant sequences were tested. The mean log10 HCV RNA differences for the best-performing CAP/CTM v2/MMx2 formulation in comparison to CAM were −0.05, 0.05, −0.12, −0.10, −0.44, and −0.29 for patients with GT1, GT2, GT3, GT4, GT5, and GT6 infections, respectively. GT1, GT2, and GT4 samples including isolates with known variants within the 5′ untranslated region (G145A, A165T) that were underquantified with CAP/CTM were correctly quantified with the second-version prototype. In addition, CAP/CTM v2 was able to accurately quantify the three transcripts with rare variant sequences. In conclusion, CAP/CTM v2 accurately quantifies HCV RNA across all HCV genotypes, including specimens with rare polymorphisms previously associated with underquantification. PMID:21752967

  10. Development of a second version of the Cobas AmpliPrep/Cobas TaqMan hepatitis C virus quantitative test with improved genotype inclusivity.

    PubMed

    Vermehren, Johannes; Colucci, Giuseppe; Gohl, Peter; Hamdi, Nabila; Abdelaziz, Ahmed Ihab; Karey, Ursula; Thamke, Diana; Zitzer, Heike; Zeuzem, Stefan; Sarrazin, Christoph

    2011-09-01

    Hepatitis C virus (HCV) RNA measurement has been facilitated by the introduction of real-time PCR-based assays with low limits of detection and broad dynamic ranges for quantification. In the present study, the performance of two second-version prototypes of the Cobas AmpliPrep/Cobas TaqMan HCV Quantitative Test (CAP/CTM v2) with decreased sample input volume and improved genotype inclusivity was investigated. A total of 232 serum and plasma samples derived from patients with chronic hepatitis C (genotype 1 [GT1], n = 108; GT2, n = 8; GT3, n = 24; GT4, n = 87; GT5, n = 3; and GT6, n = 2) were processed in parallel with the Cobas AmpliPrep/Cobas TaqMan HCV Test (CAP/CTM), Cobas Amplicor HCV Monitor Test v2.0 (CAM), and two second-version prototype formulations of CAP/CTM, Mastermix 1 (MMx1) and MMx2. In addition, three GT4 transcripts containing rare variant sequences were tested. The mean log(10) HCV RNA differences for the best-performing CAP/CTM v2/MMx2 formulation in comparison to CAM were -0.05, 0.05, -0.12, -0.10, -0.44, and -0.29 for patients with GT1, GT2, GT3, GT4, GT5, and GT6 infections, respectively. GT1, GT2, and GT4 samples including isolates with known variants within the 5' untranslated region (G145A, A165T) that were underquantified with CAP/CTM were correctly quantified with the second-version prototype. In addition, CAP/CTM v2 was able to accurately quantify the three transcripts with rare variant sequences. In conclusion, CAP/CTM v2 accurately quantifies HCV RNA across all HCV genotypes, including specimens with rare polymorphisms previously associated with underquantification.

  11. How To Implement a Tech Prep Program Based on the Rhode Island Model. Tech Prep Associate Degree Program. Technical Programs. Business/Office Administration Programs. Allied Health/Dental Health Programs.

    ERIC Educational Resources Information Center

    Community Coll. of Rhode Island, Warwick.

    This implementation guide contains information based on experiences that occurred during the development and implementation of the Rhode Island Tech Prep Model. It is intended to assist educators in addressing challenges and obstacles faced by the program early in the planning process. It begins with a rationale for tech prep. Rhode Island…

  12. PRESTO-PREP: a data preprocessor for the PRESTO-II code

    SciTech Connect

    Bell, M.A.; Emerson, C.J.; Fields, D.E.

    1984-07-01

    PRESTO-II is a computer code developed to evaluate possible health effects from shallow land disposal of low level radioactive wastes. PRESTO-PREP is a data preprocessor that has been developed to expedite the formation of input data sets for PRESTO-II. PRESTO-PREP utilizes a library of nuclide and risk-specific data. Given an initial waste inventory, the code creates the radionuclide portion of the associated input data set for PRESTO-II. 2 references.

  13. Minimal Awareness and Stalled Uptake of Pre-Exposure Prophylaxis (PrEP) Among at Risk, HIV-Negative, Black Men Who Have Sex with Men

    PubMed Central

    Driffin, Daniel D.; Bauermeister, Jose; Smith, Harlan; Conway-Washington, Christopher

    2015-01-01

    Abstract In the United States, rates of HIV infection are highest among black men who have sex with men (BMSM). Pre-exposure prophylaxis (PrEP) is a highly effective form of HIV prevention, but the uptake of this strategy has been slow since FDA approval in 2012, and it is unknown whether information about PrEP is reaching BMSM. Four hundred and thirty-six BMSM in Atlanta, GA were surveyed from January 2012 (6 months prior to PrEP approval) to March 2014 (20 months after approval). Analyses revealed no association between date of survey assessment and awareness of PrEP (20.5% were aware of PrEP before approval and 23.4% were aware after approval; OR=0.99 [0.98–1.02], p=0.952). In a multivariate model, BMSM unaware of PrEP reported lower rates of HIV testing knowledge, fewer experiences with HIV testing, and higher rates of transactional sex than BMSM who were aware of PrEP. Our findings suggest that there is limited understanding of PrEP and that there is considerable groundwork that needs to be achieved in order to reap the full benefits of PrEP. The current findings call attention to the need to both prioritize and better understand how to strengthen the bridge between medical advances and community uptake. PMID:26083143

  14. The Tech Prep Associate Degree Challenge: A Report of the Tech Prep Roundtable. AACC Special Reports No. 6.

    ERIC Educational Resources Information Center

    Falcone, Lisa, Ed.; Mundhenk, Robert, Ed.

    In fall 1993, a roundtable was held with leading Tech Prep practitioners to discuss the direction Tech Prep has taken since 1990 and emerging issues related to the implementation of Tech Prep Associate Degree (TPAD) programs. Stemming from the roundtable, this monograph describes Tech Prep, provides recommendations for implementation, and…

  15. The Tech Prep Associate Degree Challenge: A Report of the Tech Prep Roundtable. AACC Special Reports No. 6.

    ERIC Educational Resources Information Center

    Falcone, Lisa, Ed.; Mundhenk, Robert, Ed.

    In fall 1993, a roundtable was held with leading Tech Prep practitioners to discuss the direction Tech Prep has taken since 1990 and emerging issues related to the implementation of Tech Prep Associate Degree (TPAD) programs. Stemming from the roundtable, this monograph describes Tech Prep, provides recommendations for implementation, and…

  16. Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.

    PubMed

    Ferretti, Elisabetta; Villaescusa, J Carlos; Di Rosa, Patrizia; Fernandez-Diaz, Luis C; Longobardi, Elena; Mazzieri, Roberta; Miccio, Annarita; Micali, Nicola; Selleri, Licia; Ferrari, Giuliana; Blasi, Francesco

    2006-08-01

    The interaction of Prep1 and Pbx homeodomain transcription factors regulates their activity, nuclear localization, and likely, function in development. To understand the in vivo role of Prep1, we have analyzed an embryonic lethal hypomorphic mutant mouse (Prep1(i/i)). Prep1(i/i) embryos die at embryonic day 17.5 (E17.5) to birth with an overall organ hypoplasia, severe anemia, impaired angiogenesis, and eye anomalies, particularly in the lens and retina. The anemia correlates with delayed differentiation of erythroid progenitors and may be, at least in part, responsible for intrauterine death. At E14.5, Prep1 is present in fetal liver (FL) cMyb-positive cells, whose deficiency causes a marked hematopoietic phenotype. Prep1 is also localized to FL endothelial progenitors, consistent with the observed angiogenic phenotype. Likewise, at the same gestational day, Prep1 is present in the eye cells that bear Pax6, implicated in eye development. The levels of cMyb and Pax6 in FL and in the retina, respectively, are significantly decreased in Prep1(i/i) embryos, consistent with the hematopoietic and eye phenotypes. Concomitantly, Prep1 deficiency results in the overall decrease of protein levels of its related family member Meis1 and its partners Pbx1 and Pbx2. As both Prep1 and Meis interact with Pbx, the overall Prep1/Meis-Pbx DNA-binding activity is strongly reduced in whole Prep1(i/i) embryos and their organs. Our data indicate that Prep1 is an essential gene that acts upstream of and within a Pbx-Meis network that regulates multiple aspects of embryonic development.

  17. Development Paths in Archaeological Surveying

    NASA Astrophysics Data System (ADS)

    Tabbagh, A.

    2005-05-01

    Geophysical surveys of archaeological sites began in 1938, when an electrical survey was performed at the historical site of Williamsburg (Virginia, USA). Its full development, however, has been achieved by several European teams, which have continuously worked on it since the fifties. Geophysical survey is one step of archaeological site reconnaissance, which comprises many other non-invasive techniques such as document studies, field walking, air photo interpretation...Nevertheless solely geophysical techniques allow a direct exploration of the underground itself over a significant depth of investigation. Several physical properties can be measured to detect and map archaeological features and/or remains but electrical resistivity and magnetisation has been commonly used for fifty years and dielectric permittivity more recently. The major path of the technical evolution was to increase both the speed of the survey and the size of the area by using short measurement duration (less than 0.1 s) and to incorporate mechanical systems that allow the continuous pulling of the sensors on the field. Magnetic measurements are thus achieved either by fluxgate or optically pumped sensors, while electrical measurements are achieved by mobile multi-pole systems simultaneously over two or three different depths. In such surveys the mesh grid is 1 x 1 m or 0.5 x 0.5 m. Another aim is to limit the size of the surveyed area but to increase the geometrical resolution by using ground penetrating radars (GPR) with a very fine mesh (0.2 x 0.2 m) and by processing the data by `time slices' which allow to follow precisely the extension in depth of the different features. In addition for magnetic features, the simultaneous inversion of magnetic field and susceptibility (and soon viscosity) measurements using linear filtering allows the differentiation among the types of magnetization and allows for an improved determination of the depths of magnetic property contrasts. By considering the

  18. Framing HIV Pre-Exposure Prophylaxis (PrEP) for the General Public: How Inclusive Messaging May Prevent Prejudice from Diminishing Public Support.

    PubMed

    Calabrese, Sarah K; Underhill, Kristen; Earnshaw, Valerie A; Hansen, Nathan B; Kershaw, Trace S; Magnus, Manya; Krakower, Douglas S; Mayer, Kenneth H; Betancourt, Joseph R; Dovidio, John F

    2016-07-01

    Strategic framing of public messages about HIV pre-exposure prophylaxis (PrEP) may influence public support for policies and programs affecting access. This survey study examined how public attitudes toward PrEP differed based on the social group PrEP was described as benefiting ("beneficiary") and the moderating effect of prejudice. Members of the general public (n = 154) recruited online were randomly assigned to three beneficiary conditions: general population, gay men, or Black gay men. All participants received identical PrEP background information before completing measures of PrEP attitudes (specifying beneficiary), racism, and heterosexism. Despite anticipating greater PrEP adherence among gay men and Black gay men and perceiving PrEP as especially beneficial to the latter, participants expressed lower support for policies/programs making PrEP affordable for these groups vs. the general population. This disparity in support was stronger among participants reporting greater prejudice. Inclusive framing of PrEP in public discourse may prevent prejudice from undermining implementation efforts.

  19. Framing HIV Pre-Exposure Prophylaxis (PrEP) for the General Public: How Inclusive Messaging May Prevent Prejudice from Diminishing Public Support

    PubMed Central

    Calabrese, Sarah K.; Underhill, Kristen; Earnshaw, Valerie A.; Hansen, Nathan B.; Kershaw, Trace S.; Magnus, Manya; Krakower, Douglas S.; Mayer, Kenneth H.; Betancourt, Joseph R.; Dovidio, John F.

    2016-01-01

    Strategic framing of public messages about HIV pre-exposure prophylaxis (PrEP) may influence public support for policies and programs affecting access. This survey study examined how public attitudes toward PrEP differed based on the social group PrEP was described as benefiting (“beneficiary”) and the moderating effect of prejudice. Members of the general public (n = 154) recruited online were randomly assigned to three beneficiary conditions: general population, gay men, or Black gay men. All participants received identical PrEP background information before completing measures of PrEP attitudes (specifying beneficiary), racism, and heterosexism. Despite anticipating greater PrEP adherence among gay men and Black gay men and perceiving PrEP as especially beneficial to the latter, participants expressed lower support for policies/programs making PrEP affordable for these groups vs. the general population. This disparity in support was stronger among participants reporting greater prejudice. Inclusive framing of PrEP in public discourse may prevent prejudice from undermining implementation efforts. PMID:26891840

  20. Acceptability of Daily Use of Free Oral Pre-exposure Prophylaxis (PrEP) Among Transgender Women Sex Workers in Shenyang, China.

    PubMed

    Wang, Zixin; Lau, Joseph T F; Yang, Xueying; Cai, Yong; Gross, Danielle L; Ma, Tiecheng; Liu, Yan

    2017-07-27

    This study investigated the acceptability of daily use of free oral pre-exposure prophylaxis (PrEP) and associated factors among transgender women sex workers in Shenyang, China, following a briefing on PrEP. A total of 183 HIV negative or sero-status unknown participants completed the cross-sectional survey. The prevalence of acceptability of daily use of free oral PrEP was 61.2%. Adjusting for education level and monthly income, variables on negative attitudes toward PrEP (i.e., having concerns about the side-effects of PrEP) [Adjusted odds ratios (AOR): 0.26], perceived subjective norms (i.e., perceiving support from male partners to take PrEP) (AOR: 2.08), and perceived behavioral control (e.g., perceiving complete control over using PrEP) (AOR: 2.10-16.72) were significantly associated with acceptability of daily use of free oral PrEP. In addition, experiencing violence during sex work, perceived risk of contracting HIV from clients and probable anxiety were also significant. Future PrEP promotion campaigns should consider these factors.

  1. Transcription factor PREP1 induces EMT and metastasis by controlling the TGF-β-SMAD3 pathway in non-small cell lung adenocarcinoma.

    PubMed

    Risolino, Maurizio; Mandia, Nadia; Iavarone, Francescopaolo; Dardaei, Leila; Longobardi, Elena; Fernandez, Serena; Talotta, Francesco; Bianchi, Fabrizio; Pisati, Federica; Spaggiari, Lorenzo; Harter, Patrick N; Mittelbronn, Michel; Schulte, Dorothea; Incoronato, Mariarosaria; Di Fiore, Pier Paolo; Blasi, Francesco; Verde, Pasquale

    2014-09-09

    Pre-B-cell leukemia homeobox (Pbx)-regulating protein-1 (Prep1) is a ubiquitous homeoprotein involved in early development, genomic stability, insulin sensitivity, and hematopoiesis. Previously we have shown that Prep1 is a haploinsufficient tumor suppressor that inhibits neoplastic transformation by competing with myeloid ecotropic integration site 1 for binding to the common heterodimeric partner Pbx1. Epithelial-mesenchymal transition (EMT) is controlled by complex networks of proinvasive transcription factors responsive to paracrine factors such as TGF-β. Here we show that, in addition to inhibiting primary tumor growth, PREP1 is a novel EMT inducer and prometastatic transcription factor. In human non-small cell lung cancer (NSCLC) cells, PREP1 overexpression is sufficient to trigger EMT, whereas PREP1 down-regulation inhibits the induction of EMT in response to TGF-β. PREP1 modulates the cellular sensitivity to TGF-β by inducing the small mothers against decapentaplegic homolog 3 (SMAD3) nuclear translocation through mechanisms dependent, at least in part, on PREP1-mediated transactivation of a regulatory element in the SMAD3 first intron. Along with the stabilization and accumulation of PBX1, PREP1 induces the expression of multiple activator protein 1 components including the proinvasive Fos-related antigen 1 (FRA-1) oncoprotein. Both FRA-1 and PBX1 are required for the mesenchymal changes triggered by PREP1 in lung tumor cells. Finally, we show that the PREP1-induced mesenchymal transformation correlates with significantly increased lung colonization by cells overexpressing PREP1. Accordingly, we have detected PREP1 accumulation in a large number of human brain metastases of various solid tumors, including NSCLC. These findings point to a novel role of the PREP1 homeoprotein in the control of the TGF-β pathway, EMT, and metastasis in NSCLC.

  2. Who Will Use Pre-Exposure Prophylaxis (PrEP) and Why?: Understanding PrEP Awareness and Acceptability amongst Men Who Have Sex with Men in the UK – A Mixed Methods Study

    PubMed Central

    Frankis, Jamie; Young, Ingrid; Flowers, Paul; McDaid, Lisa

    2016-01-01

    Background Recent clinical trials suggest that pre-exposure prophylaxis (PrEP) may reduce HIV transmission by up to 86% for men who have sex with men (MSM), whilst relatively high levels of PrEP acceptability have been reported to date. This study examines PrEP awareness amongst sub-groups of MSM communities and acceptability amongst MSM in a low prevalence region (Scotland, UK), using a mixed methods design. Methods Quantitative surveys of n = 690 MSM recruited online via social and sociosexual media were analysed using descriptive statistics and multivariate logistic regression. In addition, n = 10 in-depth qualitative interviews with MSM were analysed thematically. Results Under one third (29.7%) of MSM had heard of PrEP, with awareness related to living in large cities, degree level education, commercial gay scene use and reporting an HIV test in the last year. Just under half of participants (47.8%) were likely to use PrEP if it were available but there was no relationship between PrEP acceptability and previous PrEP awareness. Younger men (18–25 years) and those who report higher risk UAI were significantly more likely to say they would use PrEP. Qualitative data described specific PrEP scenarios, illustrating how risk, patterns of sexual practice and social relationships could affect motivation for and nature of PrEP use. Conclusion These findings suggest substantial interest PrEP amongst MSM reporting HIV risk behaviours in Scotland. Given the Proud results, there is a strong case to investigate PrEP implementation within the UK. However, it appears that disparities in awareness have already emerged along traditional indicators of inequality. Our research identifies the need for comprehensive support when PrEP is introduced, including a key online component, to ensure equity of awareness across diverse MSM communities (e.g. by geography, education, gay scene use and HIV proximity), as well as to responding to the diverse informational and sexual health

  3. Who Will Use Pre-Exposure Prophylaxis (PrEP) and Why?: Understanding PrEP Awareness and Acceptability amongst Men Who Have Sex with Men in the UK--A Mixed Methods Study.

    PubMed

    Frankis, Jamie; Young, Ingrid; Flowers, Paul; McDaid, Lisa

    2016-01-01

    Recent clinical trials suggest that pre-exposure prophylaxis (PrEP) may reduce HIV transmission by up to 86% for men who have sex with men (MSM), whilst relatively high levels of PrEP acceptability have been reported to date. This study examines PrEP awareness amongst sub-groups of MSM communities and acceptability amongst MSM in a low prevalence region (Scotland, UK), using a mixed methods design. Quantitative surveys of n = 690 MSM recruited online via social and sociosexual media were analysed using descriptive statistics and multivariate logistic regression. In addition, n = 10 in-depth qualitative interviews with MSM were analysed thematically. Under one third (29.7%) of MSM had heard of PrEP, with awareness related to living in large cities, degree level education, commercial gay scene use and reporting an HIV test in the last year. Just under half of participants (47.8%) were likely to use PrEP if it were available but there was no relationship between PrEP acceptability and previous PrEP awareness. Younger men (18-25 years) and those who report higher risk UAI were significantly more likely to say they would use PrEP. Qualitative data described specific PrEP scenarios, illustrating how risk, patterns of sexual practice and social relationships could affect motivation for and nature of PrEP use. These findings suggest substantial interest PrEP amongst MSM reporting HIV risk behaviours in Scotland. Given the Proud results, there is a strong case to investigate PrEP implementation within the UK. However, it appears that disparities in awareness have already emerged along traditional indicators of inequality. Our research identifies the need for comprehensive support when PrEP is introduced, including a key online component, to ensure equity of awareness across diverse MSM communities (e.g. by geography, education, gay scene use and HIV proximity), as well as to responding to the diverse informational and sexual health needs of all MSM communities.

  4. Pre-Exposure Prophylaxis (PrEP)

    MedlinePlus

    ... Sites Podcasts QR Codes RSS Feeds Social Bookmarking Social Network Sites Text Messaging Twitter Video Games Video Sharing ... PrEP be considered for people who are HIV-negative and at very high risk for HIV infection . ...

  5. Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates

    PubMed Central

    Wellik, Deneen; Torres, Miguel; Ros, Marian

    2014-01-01

    TALE (three amino acids loop extension) homeodomain transcription factors are required in various steps of embryo development, in many adult physiological functions, and are involved in important pathologies. This review focuses on the PREP, MEIS, and PBX sub-families of TALE factors and aims at giving information on their biochemical properties, i.e., structure, interactors, and interaction surfaces. Members of the three sets of protein form dimers in which the common partner is PBX but they can also directly interact with other proteins forming higher-order complexes, in particular HOX. Finally, recent advances in determining the genome-wide DNA-binding sites of PREP1, MEIS1, and PBX1, and their partial correspondence with the binding sites of some HOX proteins, are reviewed. These studies have generated a few general rules that can be applied to all members of the three gene families. PREP and MEIS recognize slightly different consensus sequences: PREP prefers to bind to promoters and to have PBX as a DNA-binding partner; MEIS prefers HOX as partner, and both PREP and MEIS drive PBX to their own binding sites. This outlines the clear individuality of the PREP and MEIS proteins, the former mostly devoted to basic cellular functions, the latter more to developmental functions. Developmental Dynamics 243:59–75, 2014. © 2013 Wiley Periodicals, Inc. PMID:23873833

  6. Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates.

    PubMed

    Longobardi, E; Penkov, D; Mateos, D; De Florian, G; Torres, M; Blasi, Francesco

    2014-01-01

    TALE (three amino acids loop extension) homeodomain transcription factors are required in various steps of embryo development, in many adult physiological functions, and are involved in important pathologies. This review focuses on the PREP, MEIS, and PBX sub-families of TALE factors and aims at giving information on their biochemical properties, i.e., structure, interactors, and interaction surfaces. Members of the three sets of protein form dimers in which the common partner is PBX but they can also directly interact with other proteins forming higher-order complexes, in particular HOX. Finally, recent advances in determining the genome-wide DNA-binding sites of PREP1, MEIS1, and PBX1, and their partial correspondence with the binding sites of some HOX proteins, are reviewed. These studies have generated a few general rules that can be applied to all members of the three gene families. PREP and MEIS recognize slightly different consensus sequences: PREP prefers to bind to promoters and to have PBX as a DNA-binding partner; MEIS prefers HOX as partner, and both PREP and MEIS drive PBX to their own binding sites. This outlines the clear individuality of the PREP and MEIS proteins, the former mostly devoted to basic cellular functions, the latter more to developmental functions. Copyright © 2013 Wiley Periodicals, Inc.

  7. An intervention to support HIV pre-exposure prophylaxis (PrEP) adherence in HIV serodiscordant couples in Uganda

    PubMed Central

    Psaros, Christina; Haberer, Jessica E.; Katabira, Elly; Ronald, Allan; Tumwesigye, Elioda; Campbell, James D.; Wangisi, Jonathan; Mugwanya, Kenneth; Kintu, Alex; Enyakoit, Michael; Thomas, Katherine K.; Donnell, Deborah; Krows, Meighan; Kidoguchi, Lara; Ware, Norma; Baeten, Jared M.; Celum, Connie; Bangsberg, David R.; Safren, Steve A.

    2014-01-01

    Background Daily pre-exposure prophylaxis (PrEP) is an effective HIV prevention strategy, but adherence is required for maximum benefit. To date, there are no empirically supported PrEP adherence interventions. This manuscript describes the process of developing a PrEP adherence intervention and presents results on its impact on adherence. Methods The Partners PrEP Study was a placebo-controlled efficacy trial of daily oral tenofovir and emtricitabine/tenofovir PrEP among uninfected members of HIV serodiscordant couples. An ancillary adherence study was conducted at three study sites in Uganda. Participants with <80% adherence as measured by unannounced pill count received an additional adherence counseling intervention based on Lifesteps, an evidence-based HIV treatment adherence intervention, based on principles of cognitive-behavioral theory. Findings Of the 1,147 HIV seronegative participants were enrolled in the ancillary adherence study, 168 (14.6%) triggered the adherence intervention. Of participants triggering the intervention, 62% were male; median age was 32.5 years. The median number of adherence counseling sessions was 10. Mean adherence during the month before the intervention was 75.7%, and increased significantly to 84.1% in the month after the first intervention session (p<0.001). The most frequently endorsed adherence barriers at session one were travel and forgetting. Interpretation A PrEP adherence intervention was feasible in a clinical trial of PrEP in Uganda and PrEP adherence increased after the intervention. Future research should identify PrEP users with low adherence for enhanced adherence counseling and determine optimal implementation strategies for interventions to maximize PrEP effectiveness. PMID:24853311

  8. Appendix A: Rankings for All Programs in "NCTQ Teacher Prep Review 2014." [2014 Teacher Prep Review

    ERIC Educational Resources Information Center

    Greenberg, Julie; Walsh, Kate; McKee, Arthur

    2014-01-01

    The "NCTQ Teacher Prep Review" evaluates the quality of programs that provide preservice preparation of public school teachers. The rankings of all 2,400 elementary, secondary, and special education programs included in "NCTQ Teacher Prep Review 2014" are listed in this appendix as: (1) a numeric national ranking; (2)…

  9. MicroPrep: chip-based dielectrophoretic purification of mitochondria.

    PubMed

    Moschallski, Meike; Hausmann, Monika; Posch, Anton; Paulus, Aran; Kunz, Nancy; Duong, Thanh Tu; Angres, Brigitte; Fuchsberger, Kai; Steuer, Heiko; Stoll, Dieter; Werner, Simon; Hagmeyer, Britta; Stelzle, Martin

    2010-08-01

    We have developed a microfluidic system--microPrep--for subcellular fractionation of cell homogenates based on dielectrophoretic sorting. Separation of mitochondria isolated from a human lymphoblastoid cell line was monitored by fluorescence microscopy and further characterized by western blot analysis. Robust high throughput and continuous long-term operation for up to 60 h of the microPrep chip system with complex biological samples became feasible as a result of a comprehensive set of technical measures: (i) coating of the inner surfaces of the chip with BSA, (ii) application of mechanical actuators to induce periodic flow patterns, (iii) efficient cooling of the device to ensure integrity of organelle, (iv) a wide channel to provide for high fluidic throughput, and (v) integration of a serial arrangement of 10 dielectrophoretic deflector units to enable separation of samples with a high particle load without clogging. Hence, microPrep yields tens of micrograms of enriched and purified mitochondria within hours. Western blots of mitochondria fractions showed that contaminating endoplasmatic reticulum was reduced by a factor 6 when compared with samples prepared by state of the art centrifugation.

  10. Implications of HIV PrEP Trials Results

    PubMed Central

    Anton, Peter; Fletcher, Courtney V.; DeGruttola, Victor; McGowan, Ian; Becker, Stephen; Zwerski, Sheryl; Burns, David

    2011-01-01

    Abstract Six randomized clinical trials have been implemented to examine the efficacy of tenofovir disoproxil fumarate (TDF) and/or TDF/emtricitabine (TDF/FTC) as preexposure prophylaxis for HIV-1 infection (PrEP). Although largely complementary, the six trials have many similar features. As the earliest results become available, an urgent question may arise regarding whether changes should be made in the conduct of the other trials. To consider this in advance, a Consultation on the Implications of HIV Pre-Exposure Prophylaxis (PrEP) Trials Results sponsored by the Division of AIDS (DAIDS) of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), and the Bill and Melinda Gates Foundation (BMGF) was held on January 29, 2010, at the Natcher Conference Center, NIH, Bethesda, MD. Participants included basic scientists, clinical researchers (including investigators performing the current PrEP trials), and representatives from the U.S. Food and Drug Administration (FDA) and the agencies sponsoring the trials: the U.S. Centers for Disease Control and Prevention (CDC), the U.S. Agency for International Development (USAID), the BMGF, and the U.S. NIH. We report here a summary of the presentations and highlights of salient discussion topics from this workshop. PMID:20969483

  11. Implications of HIV PrEP trials results.

    PubMed

    Veronese, Fulvia; Anton, Peter; Fletcher, Courtney V; DeGruttola, Victor; McGowan, Ian; Becker, Stephen; Zwerski, Sheryl; Burns, David

    2011-01-01

    Abstract Six randomized clinical trials have been implemented to examine the efficacy of tenofovir disoproxil fumarate (TDF) and/or TDF/emtricitabine (TDF/FTC) as preexposure prophylaxis for HIV-1 infection (PrEP). Although largely complementary, the six trials have many similar features. As the earliest results become available, an urgent question may arise regarding whether changes should be made in the conduct of the other trials. To consider this in advance, a Consultation on the Implications of HIV Pre-Exposure Prophylaxis (PrEP) Trials Results sponsored by the Division of AIDS (DAIDS) of the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), and the Bill and Melinda Gates Foundation (BMGF) was held on January 29, 2010, at the Natcher Conference Center, NIH, Bethesda, MD. Participants included basic scientists, clinical researchers (including investigators performing the current PrEP trials), and representatives from the U.S. Food and Drug Administration (FDA) and the agencies sponsoring the trials: the U.S. Centers for Disease Control and Prevention (CDC), the U.S. Agency for International Development (USAID), the BMGF, and the U.S. NIH. We report here a summary of the presentations and highlights of salient discussion topics from this workshop.

  12. Heading Students towards Career Horizons. Tech-Prep Implementation Progress, 1993-1995.

    ERIC Educational Resources Information Center

    Silverberg, Marsha K.; Hulsey, Lara K.; Hershey, Alan M.

    In fall 1992, 87 percent of coordinators of funded local tech prep consortia (n=897) completed the third national evaluation survey. Findings indicated the following: formation of new consortia slowed; they grew larger and included a substantial and increasing share of school districts; middle school and postsecondary membership expanded;…

  13. Fashion Parade: Grade Six and Preps Collaborate as Buddies.

    ERIC Educational Resources Information Center

    Robertson, Kerry

    1999-01-01

    Describes a Costume Project wherein Australian Grade Six students and Prep students collaborated to produce costumes from paper, which were later paraded by the Preps at the school Opening Evening. (NH)

  14. How Much Do We Know about Drug Resistance Due to PrEP Use? Analysis of Experts’ Opinion and Its Influence on the Projected Public Health Impact

    PubMed Central

    Dimitrov, Dobromir T.; Boily, Marie-Claude; Hallett, Timothy B.; Albert, Jan; Boucher, Charles; Mellors, John W.; Pillay, Deenan; van de Vijver, David A. M. C.

    2016-01-01

    Background Randomized controlled trials reported that pre-exposure prophylaxis (PrEP) with tenofovir and emtricitabine rarely selects for drug resistance. However, drug resistance due to PrEP is not completely understood. In daily practice, PrEP will not be used under the well-controlled conditions available in the trials, suggesting that widespread use of PrEP can result in increased drug resistance. Methods We surveyed expert virologists with questions about biological assumptions regarding drug resistance due to PrEP use. The influence of these assumptions on the prevalence of drug resistance and the fraction of HIV transmitted resistance was studied with a mathematical model. For comparability, 50% PrEP-coverage of and 90% per-act efficacy of PrEP in preventing HIV acquisition are assumed in all simulations. Results Virologists disagreed on the following: the time until resistance emergence (range: 20–180 days) in infected PrEP users with breakthrough HIV infections; the efficacy of PrEP against drug-resistant HIV (25%-90%); and the likelihood of resistance acquisition upon transmission (10%-75%). These differences translate into projections of 0.6%- 1% and 3.5%—6% infected individuals with detectable resistance 10 years after introducing PrEP, assuming 100% and 50% adherence, respectively. The rate of resistance emergence following breakthrough HIV infection and the rate of resistance reversion after PrEP use is discontinued, were the factors identified as most influential on the expected resistance associated with PrEP. Importantly, 17–23% infected individuals could virologically fail treatment as a result of past PrEP use or transmitted resistance to PrEP with moderate adherence. Conclusions There is no broad consensus on quantification of key biological processes that underpin the emergence of PrEP-associated drug resistance. Despite this, the contribution of PrEP use to the prevalence of the detectable drug resistance is expected to be small. However

  15. The Effect of Tech Prep on Students' Speed toward Graduation

    ERIC Educational Resources Information Center

    Sweat, Jewell; Fenster, Mark

    2006-01-01

    The purpose of this study was to determine if a tech prep program of study better prepared a student for success in Georgia's technical colleges. In this study, three hypotheses, which included high-school preparation, academic performance, and faster graduation of tech prep and non-tech prep students, were analyzed. Therefore, the main focus of…

  16. The Effect of Tech Prep on Students' Speed toward Graduation

    ERIC Educational Resources Information Center

    Sweat, Jewell; Fenster, Mark

    2006-01-01

    The purpose of this study was to determine if a tech prep program of study better prepared a student for success in Georgia's technical colleges. In this study, three hypotheses, which included high-school preparation, academic performance, and faster graduation of tech prep and non-tech prep students, were analyzed. Therefore, the main focus of…

  17. PrEP (Pre-Exposure Prophylaxis) 101

    MedlinePlus

    ... English Información básica sobre la Profilaxis de Pre-exposición (PrEP) Recommend on Facebook Tweet Share Compartir Download PrEP 101 Consumer Info Sheet Pre-exposure prophylaxis (or PrEP) is when people at ...

  18. Role of the pharmacist in pre-exposure chemoprophylaxis (PrEP) therapy for HIV prevention.

    PubMed

    Clauson, Kevin A; Polen, Hyla H; Joseph, Shine A; Zapantis, Antonia

    2009-01-01

    With a global estimate of 2.5 million new infections of HIV occurring yearly, discovering novel methods to help stem the spread of the virus is critical. The use of antiretroviral chemoprophylaxis for preventing HIV after accidental or occupational exposure and in maternal to fetal transmission has become a widely accepted method to combat HIV. Based on this success, pre-exposure chemoprophylaxis (PrEP) is being explored in at-risk patient populations such as injecting drug users, female sex workers and men who have sex with men. This off-label and unmonitored use has created a need for education and intervention by pharmacists and other healthcare professionals. Pharmacists should educate themselves on PrEP and be prepared to counsel patients about their means of obtaining it (e.g. borrowing or sharing medications and ordering from disreputable Internet pharmacies). They should also be proactive about medication therapy management in these patients due to clinically important drug interactions with PrEP medications. Only one trial exploring the safety and efficacy of tenofovir as PrEP has been completed thus far. However, five ongoing trials are in various stages and two additional studies are scheduled for the near future. Unfortunately, studies in this arena have met with many challenges that have threatened to derail progress. Ethical controversy surrounding post-trial care of participants who seroconvert during studies, as well as concerns over emerging viral resistance and logistical site problems, have already halted several PrEP trials. Information about these early trials has already filtered down to affected individuals who are experimenting with this unproven therapy as an "evening before pill". The potential for PrEP is promising; however, more extensive trials are necessary to establish its safety and efficacy. Pharmacists are well-positioned to play a key role in helping patients make choices about PrEP, managing their therapy, and developing policy

  19. Role of the pharmacist in pre-exposure chemoprophylaxis (PrEP) therapy for HIV prevention

    PubMed Central

    Clauson, Kevin A.; Polen, Hyla H.; Joseph, Shine A.; Zapantis, Antonia

    2008-01-01

    With a global estimate of 2.5 million new infections of HIV occurring yearly, discovering novel methods to help stem the spread of the virus is critical. The use of antiretroviral chemoprophylaxis for preventing HIV after accidental or occupational exposure and in maternal to fetal transmission has become a widely accepted method to combat HIV. Based on this success, pre-exposure chemoprophylaxis (PrEP) is being explored in at-risk patient populations such as injecting drug users, female sex workers and men who have sex with men. This off-label and unmonitored use has created a need for education and intervention by pharmacists and other healthcare professionals. Pharmacists should educate themselves on PrEP and be prepared to counsel patients about their means of obtaining it (e.g. borrowing or sharing medications and ordering from disreputable Internet pharmacies). They should also be proactive about medication therapy management in these patients due to clinically important drug interactions with PrEP medications. Only one trial exploring the safety and efficacy of tenofovir as PrEP has been completed thus far. However, five ongoing trials are in various stages and two additional studies are scheduled for the near future. Unfortunately, studies in this arena have met with many challenges that have threatened to derail progress. Ethical controversy surrounding post-trial care of participants who seroconvert during studies, as well as concerns over emerging viral resistance and logistical site problems, have already halted several PrEP trials. Information about these early trials has already filtered down to affected individuals who are experimenting with this unproven therapy as an “evening before pill”. The potential for PrEP is promising; however, more extensive trials are necessary to establish its safety and efficacy. Pharmacists are well-positioned to play a key role in helping patients make choices about PrEP, managing their therapy, and developing

  20. Production Risk Evaluation Program (PREP) - summary

    SciTech Connect

    Kjeldgaard, E.A.; Saloio, J.H.; Vannoni, M.G.

    1997-03-01

    Nuclear weapons have been produced in the US since the early 1950s by a network of contractor-operated Department of Energy (DOE) facilities collectively known as the Nuclear Weapon Complex (NWC). Recognizing that the failure of an essential process might stop weapon production for a substantial period of time, the DOE Albuquerque Operations office initiated the Production Risk Evaluation Program (PREP) at Sandia National Laboratories (SNL) to assess quantitatively the potential for serious disruptions in the NWC weapon production process. PREP was conducted from 1984-89. This document is an unclassified summary of the effort.

  1. PrEP as a feature in the optimal landscape of combination HIV prevention in sub-Saharan Africa

    PubMed Central

    McGillen, Jessica B; Anderson, Sarah-Jane; Hallett, Timothy B

    2016-01-01

    Introduction The new WHO guidelines recommend offering pre-exposure prophylaxis (PrEP) to people who are at substantial risk of HIV infection. However, where PrEP should be prioritised, and for which population groups, remains an open question. The HIV landscape in sub-Saharan Africa features limited prevention resources, multiple options for achieving cost saving, and epidemic heterogeneity. This paper examines what role PrEP should play in optimal prevention in this complex and dynamic landscape. Methods We use a model that was previously developed to capture subnational HIV transmission in sub-Saharan Africa. With this model, we can consider how prevention funds could be distributed across and within countries throughout sub-Saharan Africa to enable optimal HIV prevention (that is, avert the greatest number of infections for the lowest cost). Here, we focus on PrEP to elucidate where, and to whom, it would optimally be offered in portfolios of interventions (alongside voluntary medical male circumcision, treatment as prevention, and behaviour change communication). Over a range of continental expenditure levels, we use our model to explore prevention patterns that incorporate PrEP, exclude PrEP, or implement PrEP according to a fixed incidence threshold. Results At low-to-moderate levels of total prevention expenditure, we find that the optimal intervention portfolios would include PrEP in only a few regions and primarily for female sex workers (FSW). Prioritisation of PrEP would expand with increasing total expenditure, such that the optimal prevention portfolios would offer PrEP in more subnational regions and increasingly for men who have sex with men (MSM) and the lower incidence general population. The marginal benefit of including PrEP among the available interventions increases with overall expenditure by up to 14% (relative to excluding PrEP). The minimum baseline incidence for the optimal offer of PrEP declines for all population groups as expenditure

  2. Familiarity with and Preferences for Oral and Long-Acting Injectable HIV Pre-exposure Prophylaxis (PrEP) in a National Sample of Gay and Bisexual Men in the U.S.

    PubMed

    Parsons, Jeffrey T; Rendina, H Jonathon; Whitfield, Thomas H F; Grov, Christian

    2016-07-01

    We sought to determine preferences for oral versus long-acting injectable (LAI) PrEP among gay and bisexual men (GBM). We surveyed a national U.S. sample of 1071 GBM about forms of PrEP. LAI PrEP was found to be acceptable among 43.2 % of men when injected monthly compared with 53.6 % of men when injected every 3 months. When asked to choose between forms of PrEP, 46.0 % preferred LAI, 14.3 % oral, 21.7 % whichever was most effective, 10.1 % had no preference, and 7.8 % would not take PrEP. There were no differences in PrEP preferences by race/ethnicity, income, region of residence, or relationship status. Those unwilling to take PrEP were significantly older than those who preferred LAI PrEP and those who would take either. Those who preferred the most effective form were younger, had less education, and reported more recent club drug use. Those who reported condomless anal sex and those who thought they were good PrEP candidates were more willing to take PrEP. Long-term health and side effects were of the greatest concern for both LAI and oral PrEP. The availability of LAI PrEP has the potential to increase uptake among GBM. The results of ongoing clinical trials of LAI PrEP will need to demonstrate similar or greater efficacy as daily Truvada for uptake to be maximized.

  3. Are Thai MSM Willing to Take PrEP for HIV Prevention? An Analysis of Attitudes, Preferences and Acceptance

    PubMed Central

    Ananworanich, Jintanat; Gomez, Gabriela B.; Hallett, Timothy B.; Dybul, Mark R.; Piot, Peter

    2013-01-01

    Objective We aimed to understand the attitudes, preferences and acceptance of oral and parenteral PrEP among men who have sex with men (MSM) in Thailand. Background Pre-exposure prophylaxis (PrEP), the use of antiretrovirals to prevent HIV acquisition, has shown promising results in recent trials. To assess the potential impact of this new HIV prevention method, in addition to efficacy data, we need to understand which psychosocial factors are likely to determine its uptake among members of potential user groups. Methods and Findings Surveys of willingness to use PrEP products were administered to MSM. Spearman’s rank tests were used to uncover associations between questionnaire items. Mann-Whitney tests were performed to ascertain differences between groups. Conjoint analysis was used to examine the attitudes and preferences of MSM towards PrEP attributes. Most participants were willing to consider taking PrEP (39.2% “yes, definitely” and 49.2% “yes, probably”) and perceived PrEP as giving them new possibilities in their lives (38.5% “a lot of hope” and 55.8% “some hope”), even after being instructed of potential side effects and costs. HIV testing was considered the most important attribute and a daily pill and longer lasting injection in the arm were the preferred routes of administration. Conclusions Despite its multiple challenges, MSM in Thailand would be willing to take PrEP, even if they had to experience inconvenience and expense. If PrEP were to be implemented in Thailand, our findings show that its uptake could be considerable. PMID:23342121

  4. Effects on Student Achievement in General Chemistry following Participation in an Online Preparatory Course: ChemPrep, a Voluntary, Self-Paced, Online Introduction to Chemistry

    ERIC Educational Resources Information Center

    Botch, Beatrice; Day, Roberta; Vining, William; Stewart, Barbara; Rath, Kenneth; Peterfreund, Alan; Hart, David

    2007-01-01

    ChemPrep was developed to be a stand-alone preparatory short-course to help students succeed in general chemistry. It is Web-based and delivered using the OWL system. Students reported that the ChemPrep materials (short information pages, parameterized questions with detailed feedback, tutorials, and answers to questions through the OWL message…

  5. Effects on Student Achievement in General Chemistry following Participation in an Online Preparatory Course: ChemPrep, a Voluntary, Self-Paced, Online Introduction to Chemistry

    ERIC Educational Resources Information Center

    Botch, Beatrice; Day, Roberta; Vining, William; Stewart, Barbara; Rath, Kenneth; Peterfreund, Alan; Hart, David

    2007-01-01

    ChemPrep was developed to be a stand-alone preparatory short-course to help students succeed in general chemistry. It is Web-based and delivered using the OWL system. Students reported that the ChemPrep materials (short information pages, parameterized questions with detailed feedback, tutorials, and answers to questions through the OWL message…

  6. Towards a fair consideration of PrEP as part of combination HIV prevention in Latin America

    PubMed Central

    Ravasi, Giovanni; Grinsztejn, Beatriz; Baruch, Ricardo; Guanira, Juan Vicente; Luque, Ricardo; Cáceres, Carlos F; Ghidinelli, Massimo

    2016-01-01

    Introduction Despite progress in scaling up antiretroviral treatment, HIV prevention strategies have not been successful in significantly curbing HIV incidence in Latin America. HIV prevention interventions need to be expanded to target the most affected key populations with a combination approach, including new high impact technologies. Oral pre-exposure prophylaxis (PrEP) is recommended as additional prevention choice for individuals at higher risk of infection and could become a cost-effective prevention tool. We discuss the barriers and solutions for a fair consideration of PrEP as part of combination HIV prevention strategies in Latin America. Discussion Although demonstration projects are ongoing or being planned in a number of countries, to date no Latin American country has implemented a public PrEP programme. The knowledge of policymakers about PrEP implementation needs to be strengthened, and programmatic guidance and cost estimate tools need to be developed to support adequate planning. Despite high levels of awareness among health providers, especially if engaged in HIV or key population care, willingness to prescribe PrEP is still low due to the lack of national policies and guidelines. Key populations, especially men who have sex with men, transgender women and sex workers, have been engaged in demonstration projects, and qualitative research shows high awareness and willingness to use PrEP, especially if accessible in the public sector for free or at affordable price. Concerns of safety, adherence, effectiveness and risk compensation need to be addressed through targeted social communication strategies to improve PrEP knowledge and stimulate demand. Alliance among policymakers, civil society and representatives from key populations, healthcare providers and researchers will be critical for the design and successful implementation of PrEP demonstration projects of locally adapted delivery models. The use of mechanisms of joint negotiation and

  7. Towards a fair consideration of PrEP as part of combination HIV prevention in Latin America.

    PubMed

    Ravasi, Giovanni; Grinsztejn, Beatriz; Baruch, Ricardo; Guanira, Juan Vicente; Luque, Ricardo; Cáceres, Carlos F; Ghidinelli, Massimo

    2016-01-01

    Despite progress in scaling up antiretroviral treatment, HIV prevention strategies have not been successful in significantly curbing HIV incidence in Latin America. HIV prevention interventions need to be expanded to target the most affected key populations with a combination approach, including new high impact technologies. Oral pre-exposure prophylaxis (PrEP) is recommended as additional prevention choice for individuals at higher risk of infection and could become a cost-effective prevention tool. We discuss the barriers and solutions for a fair consideration of PrEP as part of combination HIV prevention strategies in Latin America. Although demonstration projects are ongoing or being planned in a number of countries, to date no Latin American country has implemented a public PrEP programme. The knowledge of policymakers about PrEP implementation needs to be strengthened, and programmatic guidance and cost estimate tools need to be developed to support adequate planning. Despite high levels of awareness among health providers, especially if engaged in HIV or key population care, willingness to prescribe PrEP is still low due to the lack of national policies and guidelines. Key populations, especially men who have sex with men, transgender women and sex workers, have been engaged in demonstration projects, and qualitative research shows high awareness and willingness to use PrEP, especially if accessible in the public sector for free or at affordable price. Concerns of safety, adherence, effectiveness and risk compensation need to be addressed through targeted social communication strategies to improve PrEP knowledge and stimulate demand. Alliance among policymakers, civil society and representatives from key populations, healthcare providers and researchers will be critical for the design and successful implementation of PrEP demonstration projects of locally adapted delivery models. The use of mechanisms of joint negotiation and procurement of antiretrovirals

  8. Tech-Prep/Associate Degree Program Guide: Tech Prep Associate Degree Program, Business Administration Associate Degree Program, Office Administration Associate Degree Program, Allied Health Associate Degree Program.

    ERIC Educational Resources Information Center

    Marmaras, Judy; Neri, Pat

    The Tech-Prep Associate Degree Program (TPAD) at the Community College of Rhode Island (CCRI) in Warwick, is a high school/community college partnership providing high school students with an alternative program of study focused on goal setting, basic academic skills development, and the skills needed to pursue a career in a technical, business or…

  9. Preexposure prophylaxis (PrEP) of HIV infection in France: a nationwide cross-sectional study (PREVIC study).

    PubMed

    Rosenthal, E; Piroth, L; Cua, E; Joulié, A; Ravaux, I; Chauveau, M; Lacombe, K; Cotte, L; Bonnard, P; Weiss, L; Longuet, M; Pradier, C; Cacoub, P

    2014-02-01

    Although preliminary studies showed that preexposure prophylaxis (PrEP) lowers the HIV transmission in individuals with HIV, confirmative trials are ongoing and PrEP is not routinely recommended. The aim of this study was to assess whether individuals with HIV share antiretroviral (ARV) drugs for PrEP and to describe awareness and discussion on PrEP in this population. A cross-sectional survey was conducted in France in 23 representative departments of infectious diseases and internal medicine. Physicians administered an anonymous standardized questionnaire to all individuals with HIV receiving ARVs and followed between 24 and 31 October 2011. The questionnaire included items regarding PrEP (awareness; discussion with their close circle, physician or patients' association; experience), personal sociodemographic characteristics, risk behaviors and HIV status of the participants. Five hundred and ninety three participants were recruited: male 74.2% (men who have sex with men 52.4%, heterosexuals 21.6%), member of patient's association 9.8%. Half of them (50.6%) lived with a stable partner and 35.2% with an HIV-negative partner. Almost half (41.8%) were aware and 29.5% had had discussion about PrEP. In logistic regression, awareness and discussion on PrEP were more frequent: (1) among males, in patients' association members (p< 0.001 for both) and in nonheterosexuals (p=0.023 and 0.057, respectively); (2) among women, in those not living with a stable partner (p=0.035 and p=0.03, respectively) or living with an HIV-negative partner (p=0.049 and p=0.083, respectively). One percent of the participants declared having shared ARVs with someone and 8.3% reported PrEP in their close circle. Men reporting PrEP in their close circle shared ARVs more frequently than those who did not (10.3% vs. 0.2%, p < 0.001). Today, individuals with HIV do not seem to widely share personal ARVs for PrEP with seronegative people. A significant number of individuals with HIV are aware of and

  10. US prep plant census 2008

    SciTech Connect

    Fiscor, S.

    2008-10-15

    Each year Coal Age conducts a fairly comprehensive survey of the industry to produce the US coal preparation plant survey. This year's survey shows how many mergers and acquisitions have given coal operators more coal washing capacity. The plants are tabulated by state, giving basic details including company owner, plant name, raw feed, product ash %, quality, type of plant builder and year built. 1 tab., 1 photo.

  11. The first synthesis of chem-prep varistor LAC (lightning arrestor connector) granules

    SciTech Connect

    Tuttle, B.A.; Voigt, J.A.; Andrews, L.A.

    1988-03-01

    ZnO variestor granules are the active medis for many lightning arrestor connectors (LACs). The 150 to 200 micron diameter granules provide a controlled electrical breakdown in the 400 micron gap between the electrically conductive pin and web of the connector. Tradiationally, the varistor granules are made from commercially available, reagent grade, mixed oxide powders that range in particle size from 1 to 20 microns. For the first time, we have synthesized varistor granules from chemically prepared powders developed at Sandia. These chem-prep varistor powders are more homogeneous and much finer than the mixed oxide powders; the mean particle size of the chem-prep powders is approximately 0.06 microns. LAC granules were formed from chemically prepared powders by traditional ceramic processing techniques. Although the chem-prep granules were not as spherical as the mixed oxide granules, the chem-prep granules did meet present LAC component requirements for fast-rise breakdown voltage and insulation resistance. The insulation resistance of chem-prep granules for a 200 volt pin-to-web voltage was 100 times less than for mixed oxide granules; however, both types of granules had similar insulation resistance for a 250 volt pin-to-web voltage.

  12. Potential reduced exposure products (PREPs) for smokeless tobacco users: clinical evaluation methodology.

    PubMed

    Gray, Jennifer N; Breland, Alison B; Weaver, Michael; Eissenberg, Thomas

    2008-09-01

    Several potential reduced exposure products (PREPs) for smokeless tobacco (SLT) users are marketed in the United States, though their effects are largely unknown. These products include some that are low in tobacco-specific nitrosamines (TSNs), like Stonewall, a pressed tobacco tablet, and General snus, a moist snuff product produced in Sweden. Methodology assessing the toxicant exposure and effects of cigarette-like PREPs for smokers has been developed, and might be modified for use in evaluating PREPs for SLT users. This report describes two studies examining the toxicant exposure and effects of two PREPs for SLT users. Study 1 (n = 13) consisted of four 4.5-hr laboratory sessions where SLT products (own brand, Stonewall, General snus, and tobacco-free placebo) were used for four 30-min episodes and nicotine exposure and tobacco/nicotine abstinence symptoms were measured. Study 2 (n = 19) consisted of four 5-day ad libitum use periods when participants used own brand, Stonewall, General snus, or no SLT and urinary levels of metabolites of nicotine (cotinine) and the TSN 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNAL) and abstinence symptoms were measured. Compared with own brand, Stonewall was associated with lower levels of cotinine and NNAL, while General snus was associated with similar levels of cotinine and lower levels of NNAL. Abstinence symptoms generally did not differ across tobacco conditions. These results show that clinical laboratory methods can be used to evaluate the toxicant exposure and abstinence symptom suppression associated with PREPs for SLT users.

  13. Effort Determines Success at Roxbury Prep

    ERIC Educational Resources Information Center

    Seider, Scott

    2013-01-01

    A middle school in Boston designs its curriculum and culture--from its nightly homework assignments to its Powerful Speaking Extravaganza--upon a foundation of strengthening students' motivation and ability to do the hard work necessary to accomplish their goals. Roxbury Prep's emphasis on perseverance finds support in a robust body of education…

  14. Grade Repetition in Queensland State Prep Classes

    ERIC Educational Resources Information Center

    Anderson, Robyn

    2012-01-01

    The current study considers grade repetition rates in the early years of schooling in Queensland state schools with specific focus on the pre-schooling year, Prep. In particular, it provides empirical evidence of grade repetition in Queensland state schools along with groups of students who are more often repeated. At the same time, much of the…

  15. Relationship of Technology Education to Tech Prep.

    ERIC Educational Resources Information Center

    Anderson, Lowell D.

    With increased global competition, it is imperative that secondary school programs be reformed so as to be able to turn out productive workers having basic skills in reading, writing, and mathematics and the ability to solve problems and learn new information. One proposed reform, tech prep, can be defined as a technical education alternative to…

  16. Harlem Prep (New York City, New York).

    ERIC Educational Resources Information Center

    Gordon, Edmund W.; And Others

    Founded in 1967, Harlem Prep is an independent, non-sectarian school, located in the Central Harlem section of New York City. The school currently has an enrollment of more than 600 students who range in age from 16 to over 40. The student body is primarily black, male, and from the lower socioeconimic groups. However, the student population also…

  17. Effort Determines Success at Roxbury Prep

    ERIC Educational Resources Information Center

    Seider, Scott

    2013-01-01

    A middle school in Boston designs its curriculum and culture--from its nightly homework assignments to its Powerful Speaking Extravaganza--upon a foundation of strengthening students' motivation and ability to do the hard work necessary to accomplish their goals. Roxbury Prep's emphasis on perseverance finds support in a robust body of education…

  18. PrEP for key populations in combination HIV prevention in Nairobi: a mathematical modelling study.

    PubMed

    Cremin, Ide; McKinnon, Lyle; Kimani, Joshua; Cherutich, Peter; Gakii, Gloria; Muriuki, Festus; Kripke, Katharine; Hecht, Robert; Kiragu, Michael; Smith, Jennifer; Hinsley, Wes; Gelmon, Lawrence; Hallett, Timothy B

    2017-05-01

    The HIV epidemic in the population of Nairobi as a whole is in decline, but a concentrated sub-epidemic persists in key populations. We aimed to identify an optimal portfolio of interventions to reduce HIV incidence for a given budget and to identify the circumstances in which pre-exposure prophylaxis (PrEP) could be used in Nairobi, Kenya. A mathematical model was developed to represent HIV transmission in specific key populations (female sex workers, male sex workers, and men who have sex with men [MSM]) and among the wider population of Nairobi. The scale-up of existing interventions (condom promotion, antiretroviral therapy, and male circumcision) for key populations and the wider population as have occurred in Nairobi is represented. The model includes a detailed representation of a PrEP intervention and is calibrated to prevalence and incidence estimates specific to key populations and the wider population. In the context of a declining epidemic overall but with a large sub-epidemic in MSM and male sex workers, an optimal prevention portfolio for Nairobi should focus on condom promotion for male sex workers and MSM in particular, followed by improved antiretroviral therapy retention, earlier antiretroviral therapy, and male circumcision as the budget allows. PrEP for male sex workers could enter an optimal portfolio at similar levels of spending to when earlier antiretroviral therapy is included; however, PrEP for MSM and female sex workers would be included only at much higher budgets. If PrEP for male sex workers cost as much as US$500, average annual spending on the interventions modelled would need to be less than $3·27 million for PrEP for male sex workers to be excluded from an optimal portfolio. Estimated costs per infection averted when providing PrEP to all female sex workers regardless of their risk of infection, and to high-risk female sex workers only, are $65 160 (95% credible interval [CrI] $43 520-$90 250) and $10 920 (95% CrI $4700

  19. Rethinking HIV prevention to prepare for oral PrEP implementation for young African women

    PubMed Central

    Celum, Connie L; Delany-Moretlwe, Sinead; McConnell, Margaret; van Rooyen, Heidi; Bekker, Linda-Gail; Kurth, Ann; Bukusi, Elizabeth; Desmond, Chris; Morton, Jennifer; Baeten, Jared M

    2015-01-01

    , a first-generation biomedical HIV prevention product, will inform development of new and less user-dependent PrEP formulations and delivery of an expanding choice of prevention options in HIV prevention programmes for young African women. PMID:26198350

  20. Prep/Tech: Volume 1, No. 1, Youth on homelessness

    SciTech Connect

    1995-12-31

    PREP/TECH is a skill development, academic enrichment program of U. of Toledo in Toledo OH and The Engineers Foundation of Ohio; it addresses the mathematics, science, language, and intellectual needs of about 100 African-American and Hispanic-American 7th, 8th, and 9th graders in Toledo. This summer, after 3 weeks of classes, the 80 students returned for a second 3 week session and were divided into two groups, one studying the growing problem of homelessness in America. This group researched and published a pamphlet on homelessness. This report is divided into: myths, causes, descriptions, and solutions. Finally, a brief account is given of the homelessness project.

  1. Effects on Student Achievement in General Chemistry Following Participation in an Online Preparatory Course. ChemPrep, a Voluntary, Self-Paced, Online Introduction to Chemistry

    NASA Astrophysics Data System (ADS)

    Botch, Beatrice; Day, Roberta; Vining, William; Stewart, Barbara; Rath, Kenneth; Peterfreund, Alan; Hart, David

    2007-03-01

    ChemPrep was developed to be a stand-alone preparatory short-course to help students succeed in general chemistry. It is Web-based and delivered using the OWL system. Students reported that the ChemPrep materials (short information pages, parameterized questions with detailed feedback, tutorials, and answers to questions through the OWL message system) permitted them to work independently without the need for textbook or lecture. On average, students who completed ChemPrep had higher grades in the subsequent GenChem, Nursing, and Honors chemistry courses, with a greater percentage achieving a grade of C- or higher. Participation in ChemPrep was voluntary, and more women than men responded. Students in the Honors course enrolled in ChemPrep in higher percentages than students in GenChem and Nursing. SAT and departmental math placement exam scores were used as proxy measures of prior achievement and ability. Based on these, Honors chemistry ChemPrep users were on par with their peers but performed better in the course than non-users. In GenChem and Nursing chemistry courses, ChemPrep helped students of high prior achievement and ability perform better than their achievement scores would predict. Weaker or less motivated students did not respond to the voluntary offerings of ChemPrep in the same numbers as stronger or more motivated students, and we are seeking alternate ways to reach this population.

  2. Human Resource Challenges to Integrating HIV Pre-Exposure Prophylaxis (PrEP) into the Public Health System in Kenya: A Qualitative Study.

    PubMed

    Mack, Natasha; Wong, Christina; McKenna, Kevin; Lemons, Ansley; Odhiambo, Jacob; Agot, Kawango

    2015-03-01

    Extensive planning will be necessary to integrate HIV pre-exposure prophylaxis (PrEP) into public health systems. In Bondo and Kisumu, Kenya, we conducted interviews with 16 district and provincial public health stakeholders and held consultations with 18 provincial and 23 national public health stakeholders on topics related to PrEP rollout. We coded interview transcripts and created memos summarizing responses. We documented consultation discussions through note taking. Human resource challenges identified included increased workload and insufficient personnel, the need for task shifting/sharing, training needs, infrastructural requirements, discrimination and stigma by staff towards at-risk clients, and providers' personal priorities about offering PrEP. These challenges paralleled current challenges related to integration of antiretroviral therapy (ART) and could be partially addressed prior to PrEP rollout. The recommendations for training staff are likewise grounded in lessons from ART and have practical application for program planners developing training curricula for PrEP delivery.

  3. Preschool Recreation Enrichment Program (PREP): Implementation and Resource Guide. Volume I.

    ERIC Educational Resources Information Center

    Littman, Karen; Leslie, Lin

    The document--half of which consists of appendixes--is intended as a guide for developing and implementing preschool recreation programs for handicapped children, based on the Preschool Recreation Enrichment Program (PREP) model. Information on the growth and development of both normal and handicapped preschool children is presented, touching upon…

  4. Tech Prep Marketing Guide. The Complete Book of Strategies and Practical Experiences.

    ERIC Educational Resources Information Center

    Williamson, Patty

    This guide explains the concept of marketing tech prep and provides marketing principles and strategies to promote tech prep programs. The guide covers the following topics: (1) why it is necessary to market tech prep; (2) what a comprehensive tech prep marketing plan should include; (3) targeting the benefits message; (4) marketing tech prep to…

  5. Characterization of PREP2, a paralog of PREP1, which defines a novel sub-family of the MEINOX TALE homeodomain transcription factors.

    PubMed

    Fognani, C; Kilstrup-Nielsen, C; Berthelsen, J; Ferretti, E; Zappavigna, V; Blasi, F

    2002-05-01

    TALE (three amino acid loop extension) homeodomain proteins include the PBC and the MEINOX sub-families. MEINOX proteins form heterodimer complexes with PBC proteins. Heterodimerization is crucial to DNA binding and for nuclear localization. PBC-MEINOX heterodimers bind DNA also in combination with HOX proteins, thereby modulating their DNA-binding specificity. TALE proteins therefore play crucial roles in multiple developmental and differentiation pathways in vivo. We report the identification and characterization of a novel human gene homologous to PREP1, called PREP2. Sequence comparisons indicate that PREP1 and PREP2 define a novel sub-family of MEINOX proteins, distinct from the MEIS sub-family. PREP2 is expressed in a variety of human adult tissues and displays a more restricted expression pattern than PREP1. PREP2 is capable of heterodimerizing with PBC proteins. Heterodimerization with PBX1 appears to be essential for nuclear localization of both PREP2 and PBX1. A comparison between the functional properties of PREP1 and PREP2 reveals that PREP2-PBX display a faster DNA-dissociation rate than PREP1-PBX heterodimers, suggesting different roles in controlling gene expression. Like PREP1, PREP2-PBX heterodimers are capable of forming ternary complexes with HOXB1. The analysis of some PREP2 in vitro properties suggests a functional diversification among PREP and between PREP and MEIS MEINOX proteins.

  6. The impact of patient race on clinical decisions related to prescribing HIV pre-exposure prophylaxis (PrEP): assumptions about sexual risk compensation and implications for access.

    PubMed

    Calabrese, Sarah K; Earnshaw, Valerie A; Underhill, Kristen; Hansen, Nathan B; Dovidio, John F

    2014-02-01

    Antiretroviral pre-exposure prophylaxis (PrEP) has received increasing recognition as a viable prescription-based intervention for people at risk for HIV acquisition. However, little is known about racial biases affecting healthcare providers' willingness to prescribe PrEP. This investigation sought to explore medical students' stereotypes about sexual risk compensation among Black versus White men who have sex with men seeking PrEP, and the impact of such stereotypes on willingness to prescribe PrEP. An online survey presented participants (n = 102) with a clinical vignette of a PrEP-seeking, HIV-negative man with an HIV-positive male partner. Patient race was systematically manipulated. Participants reported predictions about patient sexual risk compensation, willingness to prescribe PrEP, and other clinical judgments. Bootstrapping analyses revealed that the Black patient was rated as more likely than the White patient to engage in increased unprotected sex if prescribed PrEP, which, in turn, was associated with reduced willingness to prescribe PrEP to the patient.

  7. The Impact of Patient Race on Clinical Decisions Related to Prescribing HIV Pre-Exposure Prophylaxis (PrEP): Assumptions About Sexual Risk Compensation and Implications for Access

    PubMed Central

    Calabrese, Sarah K.; Earnshaw, Valerie A.; Underhill, Kristen; Hansen, Nathan B.; Dovidio, John F.

    2014-01-01

    Antiretroviral pre-exposure prophylaxis (PrEP) has received increasing recognition as a viable prescription-based intervention for people at risk for HIV acquisition. However, little is known about racial biases affecting healthcare providers’ willingness to prescribe PrEP. This investigation sought to explore medical students’ stereotypes about sexual risk compensation among Black versus White men who have sex with men seeking PrEP, and the impact of such stereotypes on willingness to prescribe PrEP. An online survey presented participants (n = 102) with a clinical vignette of a PrEP-seeking, HIV-negative man with an HIV-positive male partner. Patient race was systematically manipulated. Participants reported predictions about patient sexual risk compensation, willingness to prescribe PrEP, and other clinical judgments. Bootstrapping analyses revealed that the Black patient was rated as more likely than the White patient to engage in increased unprotected sex if prescribed PrEP, which, in turn, was associated with reduced willingness to prescribe PrEP to the patient. PMID:24366572

  8. Tech Prep: Pathways to Success? The Performance of Tech Prep and Non-Tech Prep Students at a Midwestern Community College.

    ERIC Educational Resources Information Center

    Krile, Donna J.; Parmer, Penelope

    This study looks at all students who participated in a Tech Prep program at Sinclair Community College, Ohio, and who first enrolled in the program between fall 1997 and spring 2001. The comparison group consisted of all non-Tech Prep students who started at Sinclair between fall 1997 and fall 2000, and who had not transferred credits from any…

  9. The NASA SETI sky survey - Recent developments

    NASA Technical Reports Server (NTRS)

    Klein, Michael J.; Gulkis, Samuel; Olsen, Edward T.; Renzetti, Nicholas A.

    1988-01-01

    NASA's Search for Extraterrestrial Intelligence (SETI) project utilizes two complimentary search strategies: a sky survey and a targeted search. The SETI team at the Jet Propulsion Laboratory have primary responsibility to develop and carry out the sky survey part of the Microwave Observing Project. The paper describes progress that has been made to develop the major elements of the survey including a two-million channel wideband spectrum analyzer system that is being developed and constructed by JPL for the Deep Space Network. The new system will be a multiuser instrument that will serve as a prototype for the SETI Sky Survey processor. This system will be used to test the signal detection and observational strategies on deep-space network antennas in the near future.

  10. Exploratory survey of Florida pharmacists' experience, knowledge, and perception of HIV pre-exposure prophylaxis.

    PubMed

    Shaeer, Kristy M; Sherman, Elizabeth M; Shafiq, Sami; Hardigan, Patrick

    2014-01-01

    To assess Florida pharmacists' experience, knowledge, and perception of human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP) and to identify areas for pharmacist training. Cross-sectional survey. Florida in March through July 2013. Florida pharmacists. In-person and online anonymous survey. Florida pharmacists' experience, knowledge, and perceptions of PrEP. 225 completed surveys were analyzed. Survey respondents were predominantly community pharmacists with mean age of 45.7 years and less than 20 years of experience. Only 22% of respondents reported dispensing PrEP to patients. Although 75% had completed HIV-related continuing education in the last 2 years, 63% were unaware of Centers for Disease Control and Prevention PrEP guidelines and 71% answered that they did not have sufficient knowledge to counsel patients with PrEP prescriptions. Importantly, 47% of respondents answered they were uncomfortable counseling patients about PrEP. By self-report, most pharmacists agreed PrEP leads to risky behavior (68%) and increased rates of sexually transmitted infections (65%), and is too costly to promote patient access (92%). Surveyed Florida pharmacists reported limited understanding of PrEP. As a widely accessible health care counseling resource, pharmacists are positioned to improve patient understanding, promote medication adherence, and enhance PrEP efficacy. Especially during PrEP implementation, when patients may receive PrEP prescriptions from non-HIV specialist prescribers, improving pharmacists' PrEP education presents a salient opportunity.

  11. Predictors of HIV-related risk perception and PrEP acceptability among young adult female family planning patients.

    PubMed

    Garfinkel, Danielle B; Alexander, Kamila A; McDonald-Mosley, Reagan; Willie, Tiara C; Decker, Michele R

    2017-06-01

    HIV pre-exposure prophylaxis (PrEP) presents new opportunities for HIV prevention. While women comprise approximately 20% of new HIV infections in the US, significant questions remain about how to most effectively facilitate PrEP uptake for this population. Family planning clinics are a dominant source of health care for young women and support an estimated 4.5 million women annually. We explore characteristics associated with HIV risk perception and PrEP acceptability among young adult women seeking reproductive health services in a high-prevalence setting. A cross-sectional, clinic-based survey was conducted with women ages 18-35 (n = 146) seeking health care at two family planning clinics in the greater Baltimore, Maryland area, from January to April 2014. An estimated 22% of women reported being worried about HIV risk, and 60% reported they would consider taking a pill daily to prevent HIV. In adjusted models, HIV-related worry was associated with having no college education, being single or dating more than one person, practicing consistent condom use during vaginal sex, and having ever traded sex. PrEP acceptability was significantly associated with being Black (71% vs. 49%, AOR 2.23, CI: 1.89-2.64) and having ever traded sex (83% vs. 58%, AOR 4.94, CI: 2.00-12.22). For women with a history of intimate partner violence (IPV), PrEP acceptability was significantly lower (57% vs. 62%, AOR .71, CI: .59-.85) relative to their non-abused counterparts. Results suggest that family planning clinics may be a natural setting for PrEP discussion and roll-out. They should be considered in the context of integrating HIV prevention with reproductive health services. Women with a trauma history may need additional support for implementing HIV prevention in the form of PrEP.

  12. Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation.

    PubMed

    Longobardi, Elena; Blasi, Francesco

    2003-10-03

    To bind DNA and to be retained in the nucleus, PBX proteins must form heterodimeric complexes with members of the MEINOX family. Therefore the balance between PBX and MEINOX must be an important regulatory feature. We show that overexpression of PREP-1 influences the level of PBX-2 protein maintaining the PREP-1-PBX balance. This effect has important functional consequences. F9 teratocarcinoma cells stably transfected with PREP-1 had an increased DNA binding activity to a PREP-PBX-responsive element. Because PREP-1 binds DNA efficiently only when dimerized to PBX, the increased DNA binding activity suggests that the level of PBX might also have increased. Indeed PREP-1-overexpressing cells had a higher level of PBX-2 and PBX-1b proteins. PBX-2 increase did not depend on increased mRNA level or a higher rate of translation but rather because of a protein stabilization process. Indeed, PBX-2 level drastically decreased after 3 h of cycloheximide treatment in control but not in PREP-1-overexpressing cells and the proteasome inhibitor MG132 prevented PBX-2 decay in control cells. Hence, dimerization with PREP-1 appears to decrease proteasomal degradation of PBX-2. Retinoic acid induces differentiation of F9 teratocarcinoma cells with a cascade synthesis of HOX proteins. In PREP-1-overexpressing cells, HOXb1 induction was more sustained (3 days versus 1 day) and the induced level of MEIS-1b, another TALE (three amino acid loop extension) protein involved in embryonal development, was higher. Thus an increase in PREP-1 leads to changes in the fate-determining HOXb1 and has therefore important functional consequences.

  13. An Evaluation of Tech Prep in Ohio. Year One Final Report.

    ERIC Educational Resources Information Center

    MGT of America, Inc., Tallahassee, FL.

    In January 1995, a private research firm conducted the first year of a 5-year evaluation of tech prep (TP) in Ohio. State- and consortium-level baseline data about the following were collected: state policies/practices for TP; role of consortia in TP; professional development of instructors/administrators for TP; selected groups'…

  14. San Diego 1995 Preparedness for Response Exercise Program (PREP) Exercise Evaluation Report.

    DTIC Science & Technology

    1996-02-01

    Center San Diego ( PWC ) (Communications, Transportation) Submarine Base, San Diego (SUBASE) (Emergency Manage - ment, Security, Waterfront...Suite 1204, Arlington, VA 22202-4302, and to the Office of Information and Regulatory Affairs, Office of Management and Budget, Washington, DC...Office of Pipeline Safety, and Mineral Management Service developed the Preparedness for Response Exercise Program (PREP). The country is divided

  15. Including an Exam P/1 Prep Course in a Growing Actuarial Science Program

    ERIC Educational Resources Information Center

    Wakefield, Thomas P.

    2014-01-01

    The purpose of this article is to describe the actuarial science program at our university and the development of a course to enhance students' problem solving skills while preparing them for Exam P/1 of the Society of Actuaries (SOA) and the Casualty Actuary Society (CAS). The Exam P/1 prep course, formally titled Mathematical Foundations of…

  16. Central Services PREP (A Curriculum for Sterilization Technicians in the Workplace). Final Report.

    ERIC Educational Resources Information Center

    Tri-County Opportunities Industrialization Center, Inc., Harrisburg, PA.

    A workplace literacy curriculum for entry-level hospital workers who sterilize medical equipment for doctors and nurses was developed, tested, and published in Harrisburg, Pennsylvania. An assessment was conducted to identify the needs of the hospital's management and the literacy skills needed by its central services prep department, and…

  17. Integrated Curriculum Activities. Integration of Vocational and Academic Learning through Tech Prep.

    ERIC Educational Resources Information Center

    Valencia Community Coll., Orlando, FL.

    The integrated learning activities in this guide were developed by a committee of educators from Osceola District Schools, Orange County Public Schools, and Valencia Community College (Florida) for a tech prep curriculum. Included are 32 communications-related activities, 30 mathematics activities, and 10 science activities. Each activity includes…

  18. Effectiveness of Previous Initiatives Similar to Programs of Study: Tech Prep, Career Pathways, and Youth Apprenticeships

    ERIC Educational Resources Information Center

    Lewis, Morgan V.

    2008-01-01

    The federal career and technical legislation reauthorized in 2006 required the recipients of its funding to offer at least one Program of Study (POS). All states have developed some components of POS through earlier initiatives, primarily Tech Prep, career pathways, and youth apprenticeship, that attempted to ease the transition of students from…

  19. Including an Exam P/1 Prep Course in a Growing Actuarial Science Program

    ERIC Educational Resources Information Center

    Wakefield, Thomas P.

    2014-01-01

    The purpose of this article is to describe the actuarial science program at our university and the development of a course to enhance students' problem solving skills while preparing them for Exam P/1 of the Society of Actuaries (SOA) and the Casualty Actuary Society (CAS). The Exam P/1 prep course, formally titled Mathematical Foundations of…

  20. Frequently Asked Questions about Tech Prep/School-to-Work Career Pathways.

    ERIC Educational Resources Information Center

    Schoelkopf, Jim

    1995-01-01

    A Portland, Oregon, high school adopted the tech-prep/school-to-work career pathway structure five years ago. This model offers a framework for a student's career development, based on a broad selection within a career path, such as human services, business and management, industrial and engineering systems, and other endeavors. Choice is flexible…

  1. Transformations. Technical Literacy Training, Retraining for Technology, Tech Prep Bridge Program.

    ERIC Educational Resources Information Center

    Edling, Walter

    This document is a series of transparency masters divided into four sections on three types of transformation programs: technical literacy training, retraining for technology, and tech prep programs. The first section includes the following: transformations development; retraining workers for technology; elements of transformations program; Lorain…

  2. Transformations. Technical Literacy Training, Retraining for Technology, Tech Prep Bridge Program.

    ERIC Educational Resources Information Center

    Edling, Walter

    This document is a series of transparency masters divided into four sections on three types of transformation programs: technical literacy training, retraining for technology, and tech prep programs. The first section includes the following: transformations development; retraining workers for technology; elements of transformations program; Lorain…

  3. The NASA SETI sky survey: Recent developments

    NASA Technical Reports Server (NTRS)

    Klein, M. J.; Gulkis, S.; Olsen, E. T.; Renzetti, N. A.

    1989-01-01

    NASA's Search for Extraterrestrial Intelligence (SETI) project utilizes two complementary search strategies: a sky survey and a targeted search. The SETI team at the Jet Propulsion Laboratory (JPL) in Pasadena, California, has primary responsibility to develop and carry out the sky survey part. Described here is progress that has been made developing the major elements of the survey including a 2-million channel wideband spectrum analyzer system that is being designed and constructed by JPL for the Deep Space Network (DSN). The system will be a multiuser instrument; it will serve as a prototype for the SETI sky survey processor. This prototype system will be used to test the signal detection and observational strategies on DSN antennas in the near future.

  4. Early Childhood Education. PREP-37.

    ERIC Educational Resources Information Center

    Chow, Stanley; And Others

    Programs that represent major curriculum development efforts in early childhood education are described as to goals and objectives, content and materials, classroom activities, parent involvement, professional and paraprofessional training, administrative requirements and costs, program development and evaluation, and program history and present…

  5. Efficacy of oral pre-exposure prophylaxis (PrEP) for HIV among women with abnormal vaginal microbiota: a post-hoc analysis of the randomised, placebo-controlled Partners PrEP Study.

    PubMed

    Heffron, Renee; McClelland, R Scott; Balkus, Jennifer E; Celum, Connie; Cohen, Craig R; Mugo, Nelly; Bukusi, Elizabeth; Donnell, Deborah; Lingappa, Jairam; Kiarie, James; Fiedler, Tina; Munch, Matthew; Fredricks, David N; Baeten, Jared M

    2017-10-01

    62% vs 76·72%; pinteraction=0·652); or between those with Lactobacillus spp morphotypes and those without (70·48% vs 74·08%; pinteraction=0·86). Among African women with a high prevalence of bacterial vaginosis and high adherence to PrEP, the efficacy of daily oral PrEP for HIV prevention did not differ significantly among women with abnormal versus healthy vaginal microbiota as defined by Nugent score. These data are reassuring that oral PrEP delivery to women can continue without the need for concurrent testing for bacterial vaginosis or vaginal dysbiosis. Bill & Melinda Gates Foundation, Eunice Kennedy Shriver National Institute of Child Health and Human Development, and National Institute of Allergy and Infectious Diseases. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Quality improvement: single-field sterile scrub, prep, and dwell for laparoscopic hysterectomy.

    PubMed

    O'Hanlan, Katherine A; McCutcheon, Stacey Paris; McCutcheon, John G; Charvonia, Beth E

    2013-05-01

    The vulva and vaginal interior are considered a contaminated surgical area, and current OR guidelines require surgeons who are gloved and gowned at the abdominal field to avoid contact with the urethral catheter, the uterine manipulator, and the introitus or to change their gloves and even regown if contact occurs. It is our belief that the perception of the vaginal field as contaminated reflects a lack of specific standards for the preoperative cleansing of the deeper vagina and a lack of preoperative prep instructions for the combined fields. We developed a comprehensive single-field prep technique designed to improve surgical efficiency and prevent contamination of the sterile field. Combining a methodical scrub, prep, and dwell, this technique allows the entire abdomino-perineovaginal field to be treated as a single sterile field for laparoscopic procedures. Our surgical site infection rate of 1.8% when using this single-field prep technique and the subsequent surgical treatment of the abdominal, vaginal, and perineal fields as a single sterile field is well within reported norms.

  7. Development of the TTF TPACK Survey Instrument

    ERIC Educational Resources Information Center

    Jamieson-Proctor, Romina; Albion, Peter; Finger, Glenn; Cavanagh, Rob; Fitzgerald, Robert; Bond, Trevor; Grimbeek, Peter

    2013-01-01

    One of the major outcomes from the national Teaching Teachers for the Future (TTF) Project in 2011 was the development and statistical validation of a survey instrument to measure the Technological Pedagogical Content Knowledge (TPACK) of pre-service teachers as a result of the TTF intervention implemented across all Australian Education…

  8. Development of the TTF TPACK Survey Instrument

    ERIC Educational Resources Information Center

    Jamieson-Proctor, Romina; Albion, Peter; Finger, Glenn; Cavanagh, Rob; Fitzgerald, Robert; Bond, Trevor; Grimbeek, Peter

    2013-01-01

    One of the major outcomes from the national Teaching Teachers for the Future (TTF) Project in 2011 was the development and statistical validation of a survey instrument to measure the Technological Pedagogical Content Knowledge (TPACK) of pre-service teachers as a result of the TTF intervention implemented across all Australian Education…

  9. Implementing Tech Prep: A Guide to Planning a Quality Initiative.

    ERIC Educational Resources Information Center

    Bragg, Debra D.; And Others

    This guide provides perspectives about Technical Preparation (tech prep) from personnel representing the 50 state agencies and many local consortia. The guide also explores an approach to implementing tech prep based on the concept of total quality management (TQM). Each chapter begins with an overview that provides background, a summary, and list…

  10. How To Start a Prep Physics Course

    NASA Astrophysics Data System (ADS)

    Wall, Jesse D.

    1998-04-01

    At City College, we follow our mother institution, the University of California at Berkeley, in that we require high school physics as a prerequisite for general college physics and then provide a one-semester prep physics course as an alternative to meet this prerequisite. Many people have asked me how they can start such a course. In traveling about on my sabbatical, doing Physics Of Magic (1) at various schools, I have observed how various schools implement this prerequisite course. I will discuss my observations.

  11. HIV Pre-exposure Prophylaxis (PrEP) in the United States: Impact on Lifetime Infection Risk, Clinical Outcomes, and Cost-effectiveness

    PubMed Central

    Paltiel, A. David; Freedberg, Kenneth A.; Scott, Callie A.; Schackman, Bruce R.; Losina, Elena; Wang, Bingxia; Seage, George R.; Sloan, Caroline E.; Sax, Paul E.; Walensky, Rochelle P.

    2010-01-01

    Background The combination of tenofovir and emtricitabine (TDF/FTC) shows promise as HIV pre-exposure prophylaxis (PrEP). We sought to forecast clinical, epidemiologic, and economic outcomes of PrEP, taking into account uncertainties regarding efficacy, risk of resistance and toxicity, behavioral disinhibition, and drug costs. Methods We adapted a computer simulation of HIV acquisition, detection, and care to model PrEP in high-risk (1.6% average annual HIV incidence) men who have sex with men (MSM) in the United States. Base case assumptions included: 50% PrEP efficacy and $753 monthly TDF/FTC costs. We used sensitivity analyses to examine the stability of results and to identify critical input parameters. Results In a cohort with mean age 34 years, PrEP reduced lifetime HIV infection risk from 44% to 25% and increased average life expectancy from 39.9 to 40.7 years (21.7 to 22.2 discounted, quality-adjusted life-years or QALYs). Discounted mean lifetime treatment costs increased from $81,100 to $232,700 per person, indicating an incremental cost-effectiveness ratio (ICER) of $298,000 per QALY gained. Markedly larger reductions in lifetime infection risk (from 43.5% to 5.8%) were observed assuming greater (90%) PrEP efficacy. More favorable ICERs were obtained by targeting younger, higher-incidence populations and with improvements in the efficacy and cost of PrEP. Conclusions PrEP could substantially reduce HIV transmission in high-risk populations in the United States. Although it is unlikely to confer sufficient benefits to justify current TDF/FTC costs, price reductions and/or increases in efficacy could make PrEP a cost-effective option in younger or higher-risk populations. Given recent disappointments in HIV prevention and vaccine development, further study of PrEP-based HIV prevention is warranted. PMID:19193111

  12. Preferences for Injectable PrEP Among Young U.S. Cisgender Men and Transgender Women and Men Who Have Sex with Men.

    PubMed

    Biello, Katie B; Hosek, Sybil; Drucker, Morgan T; Belzer, Marvin; Mimiaga, Matthew J; Marrow, Elliot; Coffey-Esquivel, Julia; Brothers, Jennifer; Mayer, Kenneth H

    2017-09-19

    Young men who have sex with men account for approximately 20% of incident HIV infections in the U.S. Antiretroviral pre-exposure prophylaxis (PrEP) administered as a daily pill has been shown to decrease HIV acquisition in at-risk individuals. New modalities for PrEP are being developed and tested, including injectable PrEP; however, acceptability of these emerging modalities has not yet been examined in youth. We conducted six focus groups with 36 young men and transgender men and women who have sex with men in Boston, Chicago, and Los Angeles in 2016 to assess interest in and preference for different PrEP modalities. Youth were purposively recruited based on diversity of age, race/ethnicity, and prior PrEP experience. Data were coded using content coding based on key domains of the interview guide, in particular around the central themes of interest in and barriers and facilitators to injectable PrEP use. Participants were knowledgeable about oral PrEP but suggested barriers to broader uptake, including stigma, marginalization, and access to information. While participants were split on preference for injectable versus oral PrEP, they agreed quarterly injections may be more manageable and better for those who have adherence difficulties and for those who engage in sex more frequently. Concerns specific to injectable PrEP included: severity/duration of side effects, pain, level of protection prior to next injection, distrust of medical system and injections, and cost. Understanding barriers to and preferences for diverse prevention modalities will allow for more HIV prevention options, improved products, and better interventions, thus allowing individuals to make informed HIV prevention choices.

  13. Dr. Sadik's remarks at PrepCom press conference.

    PubMed

    Sadik, N

    1994-04-01

    Government officials and representatives from nongovernmental organizations attended the April, 1994, and earlier PrepCom meetings to prepare for the International Conference on Population and Development (ICPD) in Cairo. Unprecedented population growth, wasteful consumption, depletion of natural resources, increased environmental pollution, widespread poverty, and socioeconomic inequality face the earth. An international consensus exists on the importance of population and the need to focus on the individual and individual choice as the basis for balancing population and resources. Accessible, high quality family planning programs are needed to allow women to make their own choices about family size. Such programs will save many lives each year and slow population growth in developing countries, which often find it hard to provide the people with food, shelter, employment, education, and health. Governments and the international community have already contributed to falling fertility rates in developing countries (1960s- 1994: from 6-7 children to 3-4 children). Around 55% of couples and persons now use a family planning method, an almost 5-fold increase since 1965. Yet, the population is still growing (5.7 to 7.27-7.92 billion projected between 1994 and 2015). A draft Programme of Action has 20-year goals for mortality reduction, universal availability and accessibility to family planning information and services, and completion of at least primary education, particularly for girls. PrepCom is optimistic that the goals can be achieved. A key challenge is providing contraceptives to the 120 million women who want to use them but do not have access to them. Women worldwide want fewer children and high quality reproductive health care (family planning, pre- and postnatal care, STD/AIDS care). The cost for population activities is around $13 billion/year by 2000. International donors would need to increase their assistance by about 4 times to achieve this amount. The

  14. Facilitators and Barriers to Participation in PrEP HIV Prevention Trials Involving Transgender Male and Female Adolescents and Emerging Adults.

    PubMed

    Fisher, Celia B; Fried, Adam L; Desmond, Margaret; Macapagal, Kathryn; Mustanski, Brian

    2017-06-01

    Despite the disproportionate burden of HIV facing transgender youth, they continue to be under-represented in studies to provide an empirical basis for pre-exposure prophylaxis (PrEP) programs that can meet the unique needs of this population. This study examined facilitators and barriers to participation in a PrEP adherence study, determined through an online survey administered to 90 transgender male and 60 transgender female 14-21-year-olds attracted to cisgender male sexual partners. Approximately 50% reported likely to participate in the PrEP study. Participation facilitators included prior sexual and health service experiences and study access to PrEP and health services. Participation barriers included lack of concern about HIV, potential medication side effects, the logistics of quarterly meetings, remembering to take PrEP daily, and reluctance to discuss gender identity with study staff. Results suggest that successful recruitment and retention of transgender youth in PrEP prevention studies warrant protocols designed to address these barriers.

  15. The Texas Tech Prep Consortia: Strategies for Advancing Academic and Technical Education.

    ERIC Educational Resources Information Center

    Hensley, Oliver D., Ed.; And Others

    This book contains 30 chapters on the tech prep initiative in Texas: "The Identity of Tech Prep in Texas" (Tunstall); "A Snap-Shot of the Impact of the Tech Prep Initiative in the Governor's 24 Planning Regions" (Brown); "The Tech Prep Consortium Directors: The Architects for the Future of Texas" (Hensley et al.);…

  16. Developing Gyrfalcon surveys and monitoring for Alaska

    USGS Publications Warehouse

    Fuller, Mark R.; Schempf, Philip F.; Booms, Travis L.

    2011-01-01

    We developed methods to monitor the status of Gyrfalcons in Alaska. Results of surveys and monitoring will be informative for resource managers and will be useful for studying potential changes in ecological communities of the high latitudes. We estimated that the probability of detecting a Gyrfalcon at an occupied nest site was between 64% and 87% depending on observer experience and aircraft type (fixed-wing or helicopter). The probability of detection is an important factor for estimating occupancy of nesting areas, and occupancy can be used as a metric for monitoring species' status. We conclude that surveys of nesting habitat to monitor occupancy during the breeding season are practical because of the high probability of seeing a Gyrfalcon from aircraft. Aerial surveys are effective for searching sample plots or index areas in the expanse of the Alaskan terrain. Furthermore, several species of cliff-nesting birds can be surveyed concurrently from aircraft. Occupancy estimation also can be applied using data from other field search methods (e.g., from boats) that have proven useful in Alaska. We believe a coordinated broad-scale, inter-agency, collaborative approach is necessary in Alaska. Monitoring can be facilitated by collating and archiving each set of results in a secure universal repository to allow for statewide meta-analysis.

  17. Potential reduced exposure products (PREPs) in industry trial testimony.

    PubMed

    Wayne, Geoffrey Ferris

    2006-12-01

    To identify patterns in trial testimony that may reflect on the intentions or expectations of tobacco manufacturers with regard to the introduction of potential reduced exposure products (PREPs). Research was conducted using the Deposition and Trial Testimony Archive (DATTA) collection of trial testimony and depositions housed online at Tobacco Documents Online (www.tobaccodocuments.org). Relevant testimony was identified through full-text searches of terms indicating PREPs or harm reduction strategies. The role and function of PREPs in testimony were classified according to common and contrasting themes. These were analysed in the context of broader trial arguments and against changes in time period and the market. Analysis of testimony suggests that the failure of PREPs in the market tempered initial industry enthusiasm and made protection of the conventional cigarette market its major priority. The "breakthrough" character of PREPs has been de-emphasised, with trial arguments instead positioning PREPs as simply another choice for consumers. This framework legitimises the sale of conventional brands, and shifts the responsibility for adoption of safer products from the manufacturer to the consumer. Likewise, testimony has abandoned earlier dramatic health claims made with regard to PREPs, which had undermined industry arguments regarding efforts to reduce harm in conventional products. More recent testimony advocates the broad acceptance of independent guidelines that would validate use of health claims and enable the industry to market PREPs to consumers. Trial testimony reflects the changing role and positioning of PREPs by the tobacco industry. The findings are of particular importance with regard to future evaluation and potential regulation of reduced harm products.

  18. Clinician Attitudes Toward CDC Interim Pre-Exposure Prophylaxis (PrEP) Guidance and Operationalizing PrEP for Adolescents

    PubMed Central

    Lally, Michelle; Zimet, Gregory; Kahn, Jessica A.

    2015-01-01

    Abstract Prior to issuing formal HIV pre-exposure prophylaxis (PrEP) clinical practice guidelines in 2014, the US Centers for Disease Control and Prevention (CDC) had released interim guidance for oral PrEP use among adults. Because oral PrEP may be used off-label for youth and may soon be indicated for minor adolescents, we examined the potential adoption of the interim guidance among clinicians who care for HIV-infected and at-risk youth. Individual, semi-structured interviews were conducted with 15 US clinicians who were recruited through an adolescent HIV research network. The theory-driven interview guide, consisting primarily of open-ended questions, assessed demographics, familiarity with the guidance, attitudes toward the guidance, and attitudes toward the use of the guidance for adult and adolescent patients. Transcripts were analyzed using framework analysis. Most clinicians (11/15) reported that the guidance was compatible with their practice, although several reported that some aspects, particularly frequency of follow-up visits, needed to be tailored to meet their patients' needs. We found variability in clinician reported characteristics of appropriate PrEP candidates (e.g., youth with substance use and mental health issues were noted to be both suitable and unsuitable PrEP candidates) and PrEP use in serodiscordant couples (e.g., whether PrEP would be recommended to a patient whose HIV-infected partner is virally suppressed). Clinician reported steps for initiation, monitoring, and discontinuing PrEP were largely consistent with the guidance. The observed variability in clinician practice with regard to oral PrEP may be reduced through interventions to educate clinicians about the content and rationale for guideline recommendations. PMID:25692683

  19. Pine growth following chemical site prep and postplant herbaceous weed control compared to chemical site prep only

    Treesearch

    Dwight K. Lauer; Harold E. Quicke

    2013-01-01

    Three site prep vegetation control systems were compared on two Piedmont and two Upper Coastal Plain sites. Systems were (1) a one-time site prep application of Chopper® GEN2™ 2, (2) a one-time application of Chopper® GEN2™ tank mixed with sulfometuron, and (3) two applications consisting of site prep with Chopper® GEN2™ followed by herbaceous weed control with Arsenal...

  20. The Boeing Company's Tech Prep Story: A Community College Bridge to the School-to-Work Strategy.

    ERIC Educational Resources Information Center

    Gayton, Carver; Parnell, Dale

    1996-01-01

    Reviews the Boeing Tech Prep Program, an associate degree program combining high school and community college vocational and academic curricula. Describes the three phases of the program's development: the provision of seed grants to schools, the development of an associate degree program, and the institution of an internship program. (MAB)

  1. The Boeing Company's Tech Prep Story: A Community College Bridge to the School-to-Work Strategy.

    ERIC Educational Resources Information Center

    Gayton, Carver; Parnell, Dale

    1996-01-01

    Reviews the Boeing Tech Prep Program, an associate degree program combining high school and community college vocational and academic curricula. Describes the three phases of the program's development: the provision of seed grants to schools, the development of an associate degree program, and the institution of an internship program. (MAB)

  2. Tech-Prep Competency Profiles within the Health Technologies Cluster.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains competency profiles for Ohio tech prep courses in the following 12 health technologies occupations: radiographer, respiratory care therapist, occupational therapy assistant, physical therapist assistant, registered nurse (associate degree), pharmacy technologist, medical laboratory technician, histotechnologist, emergency…

  3. Tech-Prep Competency Profiles within the Health Technologies Cluster.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document contains competency profiles for Ohio tech prep courses in the following 12 health technologies occupations: radiographer, respiratory care therapist, occupational therapy assistant, physical therapist assistant, registered nurse (associate degree), pharmacy technologist, medical laboratory technician, histotechnologist, emergency…

  4. PrEP implementation research in Africa: what is new?

    PubMed

    Cowan, Frances M; Delany-Moretlwe, Sinead; Sanders, Eduard J; Mugo, Nelly R; Guedou, Fernand A; Alary, Michel; Behanzin, Luc; Mugurungi, Owen; Bekker, Linda-Gail

    2016-01-01

    Of the two million new HIV infections in adults in 2014, 70% occurred in sub-Saharan Africa. Several African countries have already approved guidelines for pre-exposure prophylaxis (PrEP) for individuals at substantial risk of HIV as part of combination HIV prevention but key questions remain about how to identify and deliver PrEP to those at greatest need. Throughout the continent, individuals in sero-discordant relationships, and members of key populations (sex workers, men who have sex with men (MSM), transgender women and injection drug users) are likely to benefit from the availability of PrEP. In addition, adolescent girls and young women (AGYW) are at substantial risk in some parts of the continent. It has been estimated that at least three million individuals in Africa are likely to be eligible for PrEP according to WHO's criteria. Tens of demonstration projects are planned or underway across the continent among a range of countries, populations and delivery settings. In each of the target populations, there are overarching issues related to (i) creating demand for PrEP, (ii) addressing supply-side issues and (iii) providing appropriate and tailored adherence support. Critical for creating demand for PrEP is the normalization of HIV prevention. Community-level interventions which engage opinion leaders as well as empowerment interventions for those at highest risk will be key. Critical to supply of PrEP is that services are accessible for all, including for stigmatized populations. Establishing accessible integrated services provides the opportunity to address other public health priorities including the unmet need for HIV testing, contraception and sexually transmitted infections treatment. National policies need to include minimum standards for training and quality assurance for PrEP implementation and to address supply chain issues. Adherence support needs to recognize that social and structural factors are likely to have an important influence

  5. PrEP implementation research in Africa: what is new?

    PubMed Central

    Cowan, Frances M; Delany-Moretlwe, Sinead; Sanders, Eduard J; Mugo, Nelly R; Guedou, Fernand A; Alary, Michel; Behanzin, Luc; Mugurungi, Owen; Bekker, Linda-Gail

    2016-01-01

    Introduction Of the two million new HIV infections in adults in 2014, 70% occurred in sub-Saharan Africa. Several African countries have already approved guidelines for pre-exposure prophylaxis (PrEP) for individuals at substantial risk of HIV as part of combination HIV prevention but key questions remain about how to identify and deliver PrEP to those at greatest need. Throughout the continent, individuals in sero-discordant relationships, and members of key populations (sex workers, men who have sex with men (MSM), transgender women and injection drug users) are likely to benefit from the availability of PrEP. In addition, adolescent girls and young women (AGYW) are at substantial risk in some parts of the continent. It has been estimated that at least three million individuals in Africa are likely to be eligible for PrEP according to WHO's criteria. Tens of demonstration projects are planned or underway across the continent among a range of countries, populations and delivery settings. Discussion In each of the target populations, there are overarching issues related to (i) creating demand for PrEP, (ii) addressing supply-side issues and (iii) providing appropriate and tailored adherence support. Critical for creating demand for PrEP is the normalization of HIV prevention. Community-level interventions which engage opinion leaders as well as empowerment interventions for those at highest risk will be key. Critical to supply of PrEP is that services are accessible for all, including for stigmatized populations. Establishing accessible integrated services provides the opportunity to address other public health priorities including the unmet need for HIV testing, contraception and sexually transmitted infections treatment. National policies need to include minimum standards for training and quality assurance for PrEP implementation and to address supply chain issues. Adherence support needs to recognize that social and structural factors are likely to have an

  6. AirfoilPrep.py Documentation: Release 0.1.0

    SciTech Connect

    Ning, S. A.

    2013-09-01

    AirfoilPrep.py provides functionality to preprocess aerodynamic airfoil data. Essentially, the module is an object oriented version of the AirfoilPrep spreadsheet with additional functionality and is written in the Python language. It allows the user to read in two-dimensional aerodynamic airfoil data, apply three-dimensional rotation corrections for wind turbine applications, and extend the datato very large angles of attack. This document discusses installation, usage, and documentation of the module.

  7. Vulnerable infected populations and street markets for ARVs: Potential implications for PrEP rollout in the USA.

    PubMed

    Kurtz, Steven P; Buttram, Mance E; Surratt, Hilary L

    2014-04-01

    Widespread diversion of antiretroviral (ARV) medications to illicit markets has recently been documented among indigent patients in South Florida. The recent approval of ARVs for pre-exposure prophylaxis (PrEP) has the potential to broaden these illicit markets, as high-risk individuals seek ARVs without a prescription or medical supervision. Nonadherence among diverters and unsupervised use of ARVs for treatment or PrEP increase risks of treatment failure, drug resistance, and disease transmission. We report the scope of ARV diversion among substance-using men who have sex with men in South Florida. Structured interviews (N = 515) queried demographics, HIV status, mental distress, substance dependence, and sexual risks. HIV-positive participants answered questions about medical care, treatment, and ARV adherence and diversion. Median age was 39. Of 46.4% who were HIV-positive, 79.1% were prescribed ARVs. Of these, 27% reported selling/trading ARVs. Reasons for diversion were sharing/trading with friends, sale/trade for money/drugs, and sale/trade of unused medications. ARV diverters, compared to nondiverters, were more likely to be substance dependent (74.5% vs. 58.7%, p = 0.046) and have traded sex for money/drugs (60.8% vs. 32.6%, p < 0.001), and less likely to be adherent to ARVs (54.9% vs. 73.9%, p = 0.012). ARV diversion should be a particular concern in communities of high-risk men who have sex with men as uninfected men in such communities are likely to benefit most from PrEP but unlikely to have access to PrEP and necessary ancillary services through the health-care system. The implications of diversion for increased risks of treatment failure, disease transmission, and PrEP failure should be carefully considered in developing policy and behavioral supports to scaling up treatment as prevention and PrEP.

  8. Preventing HIV among adolescents with oral PrEP: observations and challenges in the United States and South Africa

    PubMed Central

    Hosek, Sybil; Celum, Connie; Wilson, Craig M; Kapogiannis, Bill; Delany-Moretlwe, Sinead; Bekker, Linda-Gail

    2016-01-01

    Introduction Adolescents and young adults aged <25 are a key population in the HIV epidemic, with very high HIV incidence rates in many geographic settings and a large number who have limited access to prevention services. Thus, any biomedical HIV prevention approach should prepare licensure and implementation strategies for young populations. Oral pre-exposure prophylaxis (PrEP) is the first antiretroviral-based prevention intervention with proven efficacy across many settings and populations, and regulatory and policy approvals at global and national levels are occurring rapidly. We discuss available data from studies in the United States and South Africa on the use of oral PrEP for HIV prevention in adolescent minors, along with some of the implementation challenges. Discussion Ongoing studies in the United States and South Africa among youth under the age of 18 should provide the safety data needed by the end of 2016 to contribute to licensure of Truvada as daily PrEP in adolescents. The challenges of completing these studies as well as foreseeable broader challenges highlighted by this work are presented. Adherence to daily PrEP is a greater challenge for younger populations, and poor adherence was associated with decreased efficacy in all PrEP trials. Individual-level barriers include limited familiarity with antiretroviral-based prevention, stigma, product storage, and social support. Structural challenges include healthcare financing for PrEP, clinician acceptability and comfort with PrEP delivery, and the limited youth-friendly health services available. These challenges are discussed in the context of the work done to date in the United States and South Africa, but will likely be magnified in the setting of limited resources in many other countries that are heavily impacted by HIV. Conclusions Adolescent populations are particularly vulnerable to HIV, and oral PrEP in these populations is likely to have an impact on population-level HIV incidence. The

  9. Survey of the Hokkaido development project

    NASA Astrophysics Data System (ADS)

    1992-03-01

    As a part of the survey of the Hokkaido development project, geothermal resources and mineral resources are investigated in the north area of Tokachi. The temperature of geothermal water is 45-77 C in the bottom of the mines of which the depth is 1000-1300 m. Application fields of geothermal water are space heating, heat source for fishery facilities, bathing, etc. Presently it is used in 10 bathing places, 10 space heating facilities and 11 agricultural and fishery facilities. It is used mostly for public facilities and will be effective for general house hot water supply and preparation of sightseeing places in the future. As measures for effective utilization, hydrothermal systems used in health community plaza, horticultural greenhouse and general house hot water supply are designed, and great effectness in energy saving and economy is indicated. There exist zeolite deposits which produce 7000 tons/year in the Seta area of Kami-Shihoro-cho surveyed. Minable amount of zeolite in the Kami-Shihoro area is estimated at 800,000 m(sup 3). Production of natural zeolite in Japan is 140,000 tons/year, which is used mostly for agricultural soil conditioner and also for industrial drying, adsorptional separation and water treatment. With the expanding utilization field, it is expected to contribute to activation of the regional economy.

  10. Fiscal 1990 geothermal development promotion survey

    NASA Astrophysics Data System (ADS)

    1992-03-01

    The development of a geothermal reservoir evaluation method is mentioned for the purpose of reducing the risk of the geothermal development and drawing up an appropriate power generation plan. As for simulators, a geothermal reservoir simulator (SING-I,II) and a geothermal well two-phase simulator (WENG) are developed. For SING-II, an evaluation is made of fracture effects in the pressure interference test, production predicting simulation using fracture models, development of a multicomponent gas-liquid two-phase simulator and a tracer simulation function. As to WENG, verification on fluids containing CO2 and survey on fluids containing NaCl are made. In the Mori area which is a model field, continued observation on reservoir pressure is conducted as well as temperature/pressure logging and chemical analysis of spouted fluids. By three-dimensional grid models of reservoirs, reappearance of natural conditions of temperature/pressure distribution and discharge into the ground surface can roughly be made, and history matching is tried to be made. Newly also in Oguni area, reappearance of natural conditions is simulated using SING-I.

  11. Identifying Correlates of Young Adults' Weight Behavior: Survey Development

    ERIC Educational Resources Information Center

    Larson, Nicole; Neumark-Sztainer, Dianne; Story, Mary; van den Berg, Patricia; Hannan, Peter J.

    2011-01-01

    Objective: To describe the development and psychometric properties of survey measures relevant to eating, physical activity, and weight-related behaviors among young adults. Methods: Focus groups and reliability testing guided the development of the Project EAT-III survey. The final survey was completed by 2287 young adults. Results: The…

  12. Identifying Correlates of Young Adults' Weight Behavior: Survey Development

    ERIC Educational Resources Information Center

    Larson, Nicole; Neumark-Sztainer, Dianne; Story, Mary; van den Berg, Patricia; Hannan, Peter J.

    2011-01-01

    Objective: To describe the development and psychometric properties of survey measures relevant to eating, physical activity, and weight-related behaviors among young adults. Methods: Focus groups and reliability testing guided the development of the Project EAT-III survey. The final survey was completed by 2287 young adults. Results: The…

  13. A novel mitochondrial and chloroplast peptidasome, PreP.

    PubMed

    Kmiec, Beata; Glaser, Elzbieta

    2012-05-01

    A novel mitochondrial and chloroplast peptidasome, the Presequence Protease (PreP) degrades organellar targeting peptides as well as other unstructured peptides up to 65 amino acid residues in length. PreP belongs to the pitrilysin oligopeptidase family (M16C) containing an inverted zinc-binding motif. The crystal structure of Arabidopsis thaliana PreP, AtPreP, refined at 2.1 Å, revealed a novel mechanism of proteolysis in which two halves of the enzyme connected by a hinge region enclose a large catalytic chamber opening and closing in response to peptide binding. Double knock-out mutant of AtPreP1 and AtPreP2 results in a severe phenotype, including decreased size and growth rate, chlorosis and organellar abnormalities, such as altered chloroplast starch content, partial loss of the integrity of the inner mitochondrial membrane and reduced mitochondrial respiration. PreP homologues are also present in yeast and humans. Interestingly, human PreP has been associated with Alzheimer's disease as it is responsible for degradation of amyloid-β peptide in brain mitochondria. Copyright © Physiologia Plantarum 2011.

  14. Enhancing Youth Participation Using the PREP Intervention: Parents' Perspectives.

    PubMed

    Anaby, Dana; Mercerat, Coralie; Tremblay, Stephanie

    2017-09-02

    Pathways and Resources for Engagement and Participation (PREP), an innovative intervention aimed at modifying the environment and coaching youth/parents, was found to be effective in improving youth participation in chosen community activities. In order to complement existing quantitative evidence, this study examined parents' perspectives on the PREP approach. Twelve parents of youth with physical disabilities (12 to 18 years old) who received the PREP approach participated in individual semi-structured interviews following the 12-week intervention delivered by an occupational therapist. Thematic analysis revealed three inter-linked themes, the first of which was informative, describing the "nature of intervention", and led to two reflective themes: "multi-faceted effects of care" and "process of care". Parents highlighted the effect of the PREP intervention in a broad sense, extending beyond the accomplishment of the selected activities. This involved improvements on the physical, emotional, and social levels as well as in autonomy. Parents also discussed how their own needs were acknowledged through the intervention and recognized the unique role of the occupational therapist in supporting this process. The findings provide additional information about the usefulness of the PREP approach and describe the various benefits generated by a single intervention. Such knowledge can expand the therapeutic options for positive, health-promoting participation.

  15. Sexual Behavior Patterns and PrEP Dosing Preferences in a large sample of North American Men who have Sex with Men

    PubMed Central

    Stack, Conor; Oldenburg, Catherine E; Mimiaga, Matthew; Elsesser, Steven Alan; Krakower, Douglas; Novak, David S.; Egan, James E.; Stall, Ron; Safren, Steve; Mayer, Kenneth H.

    2015-01-01

    Pre-exposure prophylaxis (PrEP), taken as a single daily co-formulated pill containing tenofovir-emtricitabine, is a promising intervention to reduce the likelihood of HIV acquisition in at-risk individuals, including men who have sex with men (MSM). Little is known about the acceptability of less than daily, intermittent PrEP (iPrEP) regimens. We conducted an online survey of North American MSM to characterize their sexual frequency and planning behaviors and correlate these with PrEP dosing preferences. Of the 3,217 respondents who completed the survey, 46% reported engaging in unplanned condomless anal intercourse (CAI) at least once in the prior 3 months and 8% reported engaging in CAI more than once per week. In multivariable analysis, reporting unplanned CAI was associated with lower educational level, identifying as homosexual/gay as compared to bisexual, being in a monogamous relationship, having a higher self-perceived risk of HIV acquisition, higher income, engaging in CAI more than five times in the last 3 months, and not having visited a healthcare provider in the previous year. Frequent CAI (>1×/week) was associated with being younger, identifying as homosexual/gay as compared to bisexual, being in a monogamous relationship, and having a higher self-perceived risk of HIV. Having had only planned sex over the last 3 months was associated with a preference for event-based PrEP, while having frequent or unplanned CAI was associated with a preference for daily or time-driven PrEP regimens, respectively. Our findings suggest that preferences for different PrEP regimens are associated with the sexual frequency and planning behaviors of potential users. PMID:26371786

  16. Using Online Settings to Identify Gay and Bisexual Men Willing to Take or With Experience Taking PrEP: Implications for Researchers and Providers.

    PubMed

    Grov, Christian; Rendina, H Jonathon; Jimenez, Ruben; Parsons, Jeffrey T

    2016-10-01

    Given the ongoing HIV epidemic, it is essential to identify gay and bisexual men who are interested in starting PrEP as well as active PrEP users. We report on online survey data gathered over a 17-month period in 2014-2015 from gay and bisexual men identified through six sources of recruitment (n = 2903): Facebook, a hookup website, two geosocial-sexual networking apps (herein "App 1: Pop-up ads" and "App 2: Banner ads"), and two types of listservs (one focused on general gay nightlife, and one focused on gay sex parties). Willingness to take PrEP were as follows: sex party listservs (71.3%), both apps (69.8%), Facebook (67.6%), hookup website (65.2%), and nightlife listservs (50.5%). Experience having taken PrEP was as follows: sex party listservs (23.4%), App 2: Banner ads (22.5%), nightlife listservs (17.1) Facebook (14.2%), App 1: Pop-up ads (12.4%), and hookup website (2.1%). In multivariable modeling, willingness to go on PrEP was independently associated with being younger, single, a person of color, and having been tested for HIV in the past 12 months. Source of recruitment was largely unassociated with willingness to start PrEP. Number of recent male partners, number of recent condomless anal sex (CAS) events, and when data were collected (i.e., time in months) were not significantly associated with willingness to start PrEP. In multivariable models, experience having taken PrEP was positively associated with sexual identity as gay, number of recent male sex partners, number of recent CAS acts, being tested for HIV in the past 12 months, and time (in months). Experience taking PrEP varied greatly by recruitment source, suggesting both researchers and providers might be well served to utilize digital mediums to effectively identify these individuals; however, should do so with caution as not all digital options may prove fruitful.

  17. Development of a survey to identify vaccine-hesitant parents

    PubMed Central

    Mangione-Smith, Rita; Taylor, James A; Korfiatis, Carolyn; Wiese, Cheryl; Catz, Sheryl; Martin, Diane P

    2011-01-01

    Objective To develop a survey to accurately assess parental vaccine hesitancy. Results The initial survey contained 17 items in four content domains: (1) immunization behavior; (2) beliefs about vaccine safety and efficacy; (3) attitudes about vaccine mandates and exemptions; and (4) trust. Focus group data yielded an additional 10 survey items. Expert review of the survey resulted in the deletion of nine of 27 items and revisions to 11 of the remaining 18 survey items. Parent pretesting resulted in the deletion of one item, the addition of one item, the revision of four items, and formatting changes to enhance usability. The final survey contains 18 items in the original four content domains. Methods An iterative process was used to develop the survey. First, we reviewed previous studies and surveys on parental health beliefs regarding vaccination to develop content domains and draft initial survey items. Focus groups of parents and pediatricians generated additional themes and survey items. Six immunization experts reviewed the items in the resulting draft survey and ranked them on a 1–5 scale for significance in identifying vaccine-hesitant parents (5 indicative of a highly significant item). The lowest third of ranked items were dropped. The revised survey was pretested with 25 parents to assess face validity, usability and item understandability. Conclusions The Parent Attitudes about Childhood Vaccines survey was constructed using qualitative methodology to identify vaccine-hesitant parents and has content and face validity. Further psychometric testing is needed. PMID:21389777

  18. Selected Outcomes Related to Tech Prep Implementation by Illinois Consortia, 2001-2005

    ERIC Educational Resources Information Center

    Bragg, Debra D.; Kirby, Catherine; Zhu, Rongchun

    2006-01-01

    This report is the summary of key aspects of Tech Prep in Illinois over the five year period of 2001-2005 during which all Tech Prep consortia provided annual data based on federal legislative requirements and state-determined essential elements of successful programs. These annual Tech Prep reports enable local educators to monitor student…

  19. 34 CFR 406.1 - What is the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What is the State-Administered Tech-Prep Education... (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION STATE-ADMINISTERED TECH-PREP EDUCATION PROGRAM General § 406.1 What is the State-Administered Tech-Prep Education Program? If the...

  20. 34 CFR 406.1 - What is the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false What is the State-Administered Tech-Prep Education... (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION STATE-ADMINISTERED TECH-PREP EDUCATION PROGRAM General § 406.1 What is the State-Administered Tech-Prep Education Program? If the...

  1. 34 CFR 406.1 - What is the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false What is the State-Administered Tech-Prep Education... (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION STATE-ADMINISTERED TECH-PREP EDUCATION PROGRAM General § 406.1 What is the State-Administered Tech-Prep Education Program? If the...

  2. 34 CFR 406.1 - What is the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false What is the State-Administered Tech-Prep Education... (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION STATE-ADMINISTERED TECH-PREP EDUCATION PROGRAM General § 406.1 What is the State-Administered Tech-Prep Education Program? If the...

  3. 34 CFR 406.1 - What is the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false What is the State-Administered Tech-Prep Education... (Continued) OFFICE OF VOCATIONAL AND ADULT EDUCATION, DEPARTMENT OF EDUCATION STATE-ADMINISTERED TECH-PREP EDUCATION PROGRAM General § 406.1 What is the State-Administered Tech-Prep Education Program? If the...

  4. The College Pairs Study: Evaluation of Tech-Prep in New York State.

    ERIC Educational Resources Information Center

    Brodsky, Stanley M.; Arroyo, Carmen G.

    This document is part of a series of reports of a Statewide Evaluation Study of the Tech-Prep Program in New York State. The Pairs Study involved analysis of Tech-Prep vs. non-Tech-Prep student performance using 14 pairs of institutions - one college and its feeder high school. Research utilized high school and college transcripts for 391 students…

  5. 2014 Teacher Prep Review: A Review of the Nation's Teacher Preparation Programs

    ERIC Educational Resources Information Center

    Greenberg, Julie; Walsh, Kate; McKee, Arthur

    2014-01-01

    "Teacher Prep Review 2014" is the second edition of the National Council on Teacher Quality's (NCTQ's) annual assessment of the nation's 2,400 teacher prep programs. The "Review" uncovers early evidence that teacher prep programs are beginning to make changes. It arrives at a time of heightened, unprecedented…

  6. Status of Tech Prep in Missouri 1993-94. Final Report.

    ERIC Educational Resources Information Center

    Ruhland, Sheila; And Others

    A study examined the status of tech prep in Missouri as of 1993-1994. Data were gathered from a review of the request for proposals of Missouri's 12 consortia, assessment of Missouri's current status of tech prep, and structured interviews with the 12 tech prep coordinators. It was determined that up to 86 secondary schools were initially involved…

  7. California Community College Staff Development Coordinators and Program Survey, 1993.

    ERIC Educational Resources Information Center

    Anthony, Pat; Ratliffe, Sharon A.

    In August 1993, a survey was conducted of staff development coordinators (SDC's) at California community colleges to gather data on their positions and characteristics. An analysis was made of the usable surveys returned by 54 colleges and, where appropriate, results were compared with findings from 1990, 1991, and 1992 surveys of SDC's. Study…

  8. Constrained binary classification using ensemble learning: an application to cost-efficient targeted PrEP strategies.

    PubMed

    Zheng, Wenjing; Balzer, Laura; van der Laan, Mark; Petersen, Maya

    2017-04-06

    Binary classification problems are ubiquitous in health and social sciences. In many cases, one wishes to balance two competing optimality considerations for a binary classifier. For instance, in resource-limited settings, an human immunodeficiency virus prevention program based on offering pre-exposure prophylaxis (PrEP) to select high-risk individuals must balance the sensitivity of the binary classifier in detecting future seroconverters (and hence offering them PrEP regimens) with the total number of PrEP regimens that is financially and logistically feasible for the program. In this article, we consider a general class of constrained binary classification problems wherein the objective function and the constraint are both monotonic with respect to a threshold. These include the minimization of the rate of positive predictions subject to a minimum sensitivity, the maximization of sensitivity subject to a maximum rate of positive predictions, and the Neyman-Pearson paradigm, which minimizes the type II error subject to an upper bound on the type I error. We propose an ensemble approach to these binary classification problems based on the Super Learner methodology. This approach linearly combines a user-supplied library of scoring algorithms, with combination weights and a discriminating threshold chosen to minimize the constrained optimality criterion. We then illustrate the application of the proposed classifier to develop an individualized PrEP targeting strategy in a resource-limited setting, with the goal of minimizing the number of PrEP offerings while achieving a minimum required sensitivity. This proof of concept data analysis uses baseline data from the ongoing Sustainable East Africa Research in Community Health study. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  9. Social Capital: Its Constructs and Survey Development

    ERIC Educational Resources Information Center

    Enfield, Richard P.; Nathaniel, Keith C.

    2013-01-01

    This article reports on experiences and methods of adapting a valid adult social capital assessment to youth audiences in order to measure social capital and sense of place. The authors outline the process of adapting, revising, prepiloting, piloting, and administering a youth survey exploring young people's sense of community, involvement in the…

  10. Social Capital: Its Constructs and Survey Development

    ERIC Educational Resources Information Center

    Enfield, Richard P.; Nathaniel, Keith C.

    2013-01-01

    This article reports on experiences and methods of adapting a valid adult social capital assessment to youth audiences in order to measure social capital and sense of place. The authors outline the process of adapting, revising, prepiloting, piloting, and administering a youth survey exploring young people's sense of community, involvement in the…

  11. Tech-Prep for the '90s. Final Report.

    ERIC Educational Resources Information Center

    John A. Logan Coll., Carterville, IL.

    A project successfully infused tech prep into the vocational-technical programs of 10 of the 11 high schools in the John A. Logan College district in Illinois. All participating schools revised course syllabi for a portion of their academic classes indicating the use of applied materials. The Principles of Technology class was offered successfully…

  12. SPC-Prep. Instructor's Guide. Workplace Education. Project ALERT.

    ERIC Educational Resources Information Center

    Ruetz, Nancy

    This instructor's guide contains materials for a course designed to prepare employees for statistical process control (SPC) training given at their workplace by refreshing math skills and building the concepts and vocabulary necessary to understand SPC in manufacturing environments. SPC-Prep 1 addresses the math skills necessary to perform SPC…

  13. SPC-Prep 1. Participant's Manual. Workplace Education. Project ALERT.

    ERIC Educational Resources Information Center

    Ruetz, Nancy

    This companion document to the instructor's guide for a course designed to prepare employees for statistical process control (SPC) training given at their workplace by refreshing math skills and building the concepts and vocabulary necessary to understand SPC in manufacturing environments. SPC-Prep 1 addresses the math skills necessary to perform…

  14. Evolving a Model for Evaluating Tech Prep Implementation.

    ERIC Educational Resources Information Center

    Ruhland, Sheila K.; And Others

    Tech Prep programs have been designed and structured to forge strong and comprehensive links between secondary and postsecondary education institutions. Programs within these institutions lead to completion of an associate degree or two-year certificate, provide technical preparation in specified fields, build student competence, and lead to…

  15. Mentoring clinical ladder advancement with a facilitated prep class.

    PubMed

    Winslow, Susan A; Blankenship, Jean

    2007-01-01

    The authors describe a strategy for encouraging participation and overcoming reluctance of staff to participate in an optional professional advancement career ladder program. A facilitated prep class in a computer skills laboratory provides nurses with the framework for completing application requirements in a casual, supportive atmosphere.

  16. Computer-Integrated Manufacturing Technology. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Lakeland Tech Prep Consortium, Kirtland, OH.

    This tech prep competency profile for computer-integrated manufacturing technology begins with definitions for four occupations: manufacturing technician, quality technician, mechanical engineering technician, and computer-assisted design/drafting (CADD) technician. A chart lists competencies by unit and indicates whether entire or partial unit is…

  17. ClassPrep: A Peer Review System for Class Preparation

    ERIC Educational Resources Information Center

    Park, Jooyong

    2017-01-01

    Class preparation is recommended by instructors in most college courses, but checking whether a student does so is not easy. A new blended learning system, named ClassPrep, has been proposed and implemented. The usability of the system was examined for two undergraduate psychology courses: one advanced course (n = 11) and one introductory course…

  18. From High School to Work: 150 Great Tech Prep Careers.

    ERIC Educational Resources Information Center

    1998

    This book presents information on 150 careers in a wide variety of fields that fall under the broad category of tech prep. Each four- to five-page profile contains the following: definition of the occupation, the nature of the work, requirements for educational and work experiences needed to enter and advance, opportunities for experience and…

  19. Health Science Careers: Tech Prep Consortium for New Jersey.

    ERIC Educational Resources Information Center

    Maillet, Julie O'Sullivan; D'Anna, Suzanne

    2001-01-01

    A high school health sciences program consists of an interdisciplinary core curriculum, clinical job shadowing, and potential to earn college credit. Interactive television and CD-ROMs enhance teaching. A consortium of high schools offers the tech prep program in collaboration with the University of Medicine and Dentistry of New Jersey. (SK)

  20. Appendix D: More on Recommendations. [2014 Teacher Prep Review

    ERIC Educational Resources Information Center

    Greenberg, Julie; Walsh, Kate; McKee, Arthur

    2014-01-01

    The "NCTQ Teacher Prep Review" evaluates the quality of programs that provide preservice preparation of public school teachers. This appendix presents next steps for prospective college or graduate students who aspire to enter teaching (and their parents) and for current students who are already enrolled in a teacher preparation program…

  1. From High School to Work: 150 Great Tech Prep Careers.

    ERIC Educational Resources Information Center

    1998

    This book presents information on 150 careers in a wide variety of fields that fall under the broad category of tech prep. Each four- to five-page profile contains the following: definition of the occupation, the nature of the work, requirements for educational and work experiences needed to enter and advance, opportunities for experience and…

  2. Comprehensive Vocational and Applied Technology Program. Seattle Tech Prep.

    ERIC Educational Resources Information Center

    Seattle Community Coll. District, Washington.

    This package contains a program description and miscellaneous brochures about the Seattle (Washington) Public Schools' tech prep program. The program description booklet is designed to show how a comprehensive vocational and applied technology program is being introduced at Nathan Hale High School in Seattle. Included in the booklet are the…

  3. Physics and Physical Science Units for Tech Prep.

    ERIC Educational Resources Information Center

    Bielefeld, Marilyn; Daniels, Sadie; Hall, Yolanda; McClendon, Cecil; Schlinger, Gary

    Promoting ACademic Excellence in Mathematics and Science for Workers of the 21st Century (PACE) was a consortium project made up of Indiana University Northwest, the Gary Community Schools, and the Merrillville Community Schools. The focus of this project was to prepare teachers and curricula for Tech Prep mathematics and science courses for the…

  4. Computer-Integrated Manufacturing Technology. Tech Prep Competency Profile.

    ERIC Educational Resources Information Center

    Lakeland Tech Prep Consortium, Kirtland, OH.

    This tech prep competency profile for computer-integrated manufacturing technology begins with definitions for four occupations: manufacturing technician, quality technician, mechanical engineering technician, and computer-assisted design/drafting (CADD) technician. A chart lists competencies by unit and indicates whether entire or partial unit is…

  5. ClassPrep: A Peer Review System for Class Preparation

    ERIC Educational Resources Information Center

    Park, Jooyong

    2017-01-01

    Class preparation is recommended by instructors in most college courses, but checking whether a student does so is not easy. A new blended learning system, named ClassPrep, has been proposed and implemented. The usability of the system was examined for two undergraduate psychology courses: one advanced course (n = 11) and one introductory course…

  6. 29. VIEW OF GRAND CANAL, LOOKING WEST TOWARD BROPHY PREP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. VIEW OF GRAND CANAL, LOOKING WEST TOWARD BROPHY PREP AND ST. FRANCIS CHURCH (compare this photograph with AZ-17-15, taken at the same spot in 1937). Photographer: Kevin Kreisel-Coons, May 1990 - Grand Canal, North side of Salt River, Tempe, Maricopa County, AZ

  7. Model 2 + 2 + 2 Tech Prep Program in Engineering Technology.

    ERIC Educational Resources Information Center

    Hata, David M.

    In 1986, Portland Community College (PCC) received federal funding to expand its pilot 2 + 2 Tech Prep program in engineering technology to include five local high schools and to link the program to the upper-division engineering technology program at the Oregon Institute of Technology (OIT). Program results included the following: (1) eight high…

  8. California Community College Staff Development Coordinators and Program Survey, 1994.

    ERIC Educational Resources Information Center

    Stanley, Phil

    Since 1990, the California Community College (CCC) Council for Staff Development has conducted an annual survey of CCC staff development coordinators (SDC's) to gather and disseminate data on coordinators' characteristics and responsibilities. The 1994 survey received responses from 67% of the CCC's, the highest to date. An analysis of responses,…

  9. Development of an RDECOM Workforce Motivational Survey Instrument

    DTIC Science & Technology

    2016-09-01

    factors. We developed a closed-loop survey instrument and analysis methodology to identify distinct generational workforce motivational factors. Nine...United States Army Research Development and Engineering Command (RDECOM) supervisory engineers, General Schedule (GS) 14 and 15, reviewed the survey...compensation and workplace environment structure to motivate the target generational workforce demographic to improve productivity. The deliverables from this

  10. Identifying Correlates of Young Adults’ Weight Behavior: Survey Development

    PubMed Central

    Larson, Nicole; Neumark-Sztainer, Dianne; Story, Mary; van den Berg, Patricia; Hannan, Peter J.

    2012-01-01

    Objective To describe the development and psychometric properties of survey measures relevant to eating, physical activity, and weight-related behaviors among young adults. Methods Focus groups and reliability testing guided the development of the Project EAT-III survey. The final survey was completed by 2,287 young adults. Results The systematic process employed led to a psychometrically sound and developmentally appropriate survey. Test-retest reliabilities for items included on the final survey were mostly moderate to good and Cronbach’s alphas were >0.7 for 83% of developed scales. Conclusions Future studies may find the systematic process used to be helpful in creating other weight-related surveys. PMID:22251762

  11. HIV-negative male couples' attitudes about pre-exposure prophylaxis (PrEP) and using PrEP with a sexual agreement.

    PubMed

    Mitchell, Jason W; Lee, Ji-Young; Woodyatt, Cory; Bauermeister, José; Sullivan, Patrick; Stephenson, Rob

    2016-08-01

    One efficacious strategy to help prevent HIV is oral pre-exposure prophylaxis (PrEP), a daily regimen of antiretroviral treatment taken by HIV-negative individuals. Two of the recommendations of Centers for Disease Control and Prevention (CDC) guidelines for PrEP pertain to being in a relationship (i.e., male couples). Despite the recognition of how primary partners in male couples' relationships shape HIV risk and CDC's PrEP guidelines, there is a paucity of data that examine HIV-negative male couples' attitudes toward PrEP use and using PrEP with a sexual agreement. A sexual agreement is an explicit agreement made between two individuals about what sex and other related behaviors may occur within and outside of their relationship. In this qualitative study, we examine HIV-negative male couples' attitudes toward PrEP use and whether they thought PrEP could be integrated into a sexual agreement. Data for this study are drawn from couple-level interviews conducted in 2014 with 29 HIV-negative male couples who had a sexual agreement and were from Atlanta or Detroit. Both passive (e.g., flyers) and active (e.g., targeted Facebook advertisements) recruitment methods were used; the sample was stratified by agreement type. Thematic analysis was applied to identify the following themes regarding HIV-negative male couples' attitudes toward PrEP use: (1) PrEP and condom use; (2) concerns about PrEP (e.g., effectiveness, side effects, and promoting sexually risky behavior); and (3) accessibility of PrEP. Some thought PrEP could be a part of couples' agreement because it could help reduce sexual anxiety and sexual risk, and would help keep the couple safe. Others described PrEP use with an agreement as something for "others". Some were also concerned that incorporating PrEP could usurp the need for a sexual agreement in a couples' relationship. These themes highlight the need to improve informational messaging and promotion efforts about PrEP among HIV-negative male couples

  12. PrepLink: a novel web-based tool for healthcare emergency planning and response.

    PubMed

    Roth, Loren H; Criss, Kathleen; Stewart, Xavier; McCann, Kevin

    2009-03-01

    Effective planning and response to bioterrorism or other disasters, natural or manmade, requires timely and effective communication as well as situational awareness. During a catastrophic event, decision makers--including first responders, hospital workers, and command center emergency workers--will have a short time to make crucial decisions. Preparing to receive and treat patients, especially when there are mass casualties, requires immediate access to large amounts of integrated health data from disparate sources. This article describes PrepLink, a novel comprehensive web-based healthcare-related all-hazards electronic disaster management system. Over the past 3 years, PrepLink has been developed and tested at the University of Pittsburgh Medical Center in partnership with the Pennsylvania National Guard. It can be deployed in multiple sites across a region or state or more broadly. The system includes pages for public awareness about planning for and responding to disasters, as well as secure, password-protected private pages that can be used by many types of emergency and healthcare personnel who are involved in such events. Timely information related to public health, safety, planning, preparation, and response can be accessed from both sets of pages. The system permits rapid communication and sharing of team plans across disparate locations; it stores multiple key documents and contains asset inventories, a GIS, patient tracking, and a command-and-control module. Each function is directly related to providing healthcare treatment for victims. PrepLink's comprehensive and user friendly approach to health-related disaster management holds promise for future progress in this challenging arena.

  13. Development and Validation of the Educational Technologist Multimedia Competency Survey

    ERIC Educational Resources Information Center

    Ritzhaupt, Albert D.; Martin, Florence

    2014-01-01

    The purpose of this research study was to identify the multimedia competencies of an educational technologist by creating a valid and reliable survey instrument to administer to educational technology professionals. The educational technology multimedia competency survey developed through this research is based on a conceptual framework that…

  14. Development of Survey of Technological Pedagogical and Content Knowledge (TPACK)

    ERIC Educational Resources Information Center

    Sahin, Ismail

    2011-01-01

    The purpose of this study is to develop a survey of technological pedagogical and content knowledge (TPACK). The survey consists of seven subscales forming the TPACK model: 1) technology knowledge (TK), 2) pedagogy knowledge (PK), 3) content knowledge (CK), 4) technological pedagogical knowledge (TPK), 5) technological content knowledge (TCK), 6)…

  15. Development and Validation of the Educational Technologist Multimedia Competency Survey

    ERIC Educational Resources Information Center

    Ritzhaupt, Albert D.; Martin, Florence

    2014-01-01

    The purpose of this research study was to identify the multimedia competencies of an educational technologist by creating a valid and reliable survey instrument to administer to educational technology professionals. The educational technology multimedia competency survey developed through this research is based on a conceptual framework that…

  16. Developing survey grids to substantiate freedom from exotic pests

    Treesearch

    John W. Coulston; Frank H. Koch; William D. Smith; Frank J. Sapio

    2009-01-01

    Systematic, hierarchical intensification of the Environmental Monitoring and Assessment Program hexagon for North America yields a simple procedure for developing national-scale survey grids. In this article, we describe the steps to create a national-scale survey grid using a risk map as the starting point. We illustrate the steps using an exotic pest example in which...

  17. PrEP in Europe – expectations, opportunities and barriers

    PubMed Central

    McCormack, Sheena Mary; Noseda, Veronica; Molina, Jean-Michel

    2016-01-01

    Introduction In contrast to the global trend showing a decline in new HIV infections, the number reported in the World Health Organization (WHO) region of Europe is increasing. Health systems are disparate, but even countries with free access to screening and treatment observe continuing high rates of new infections in key populations, notably men who have sex with men (MSM). Pre-exposure prophylaxis (PrEP) is only available in France. This commentary describes the European epidemics and healthcare settings where PrEP could be delivered, how need might be estimated for MSM and the residual barriers to access. Discussion Health systems and government commitment to HIV prevention and care, both financial and political, differ considerably between the countries that make up Europe. A common feature is that funds for prevention are a small fraction of funds for care. Although care is generally good, access is limited in the middle-income countries of Eastern Europe and central Asia, and only 19% of people living with HIV received antiretroviral therapy in 2014. It is challenging to motivate governments or civil society to implement PrEP in the context of this unmet treatment need, which is driven by limited national health budgets and diminishing assistance from foreign aid. The high-income countries of Western Europe have hesitated to embrace PrEP for different reasons, initially due to key gaps in the evidence. Now that PrEP has been shown to be highly effective in European MSM in two randomized controlled trials, it is clear that the major barrier is the cost of the drug which is still on patent, although inadequate health systems and diminishing investment in civil society are also key challenges to overcome. Conclusions The momentum to implement PrEP in European countries is increasing and provides a welcome opportunity to expand and improve clinical services and civil society support focused on HIV and related infections including other sexually transmitted and

  18. Instructional and Organizational Effectiveness in Selected PREPS-Identified Value Added and PREPS-Identified Value Subtracted Elementary Schools in Mississippi

    ERIC Educational Resources Information Center

    Henderson, Jimmy Dale

    2011-01-01

    This study examined the perceptions of principals, teachers, and support staff at 3 PREPS-identified value added and three PREPS-identified value subtracted elementary schools in Mississippi to determine if there were "effective schools" practices in the areas of instructional and organizational systems that were unique to either group.…

  19. Willingness to Use Pre-Exposure Prophylaxis (PrEP): An Empirical Test of the Information-Motivation-Behavioral Skills (IMB) Model among High-Risk Drug Users in Treatment.

    PubMed

    Shrestha, Roman; Altice, Frederick L; Huedo-Medina, Tania B; Karki, Pramila; Copenhaver, Michael

    2017-05-01

    Evidence from recent pre-exposure prophylaxis (PrEP) trials has demonstrated its safety and efficacy in significantly reducing the risk of HIV acquisition for those who are at considerable risk of acquiring HIV infection. With a rapid increase in the amount of research on the efficacy of PrEP for HIV prevention, complementary research on the willingness to use PrEP has grown, especially among MSM, but limited research has been focused among people who use drugs (PWUD). As part of the formative process, we utilized the information-motivation-behavioral skills (IMB) model of health behavior change to characterize and guide intervention development for promoting willingness to use PrEP among high-risk PWUD. The analysis included 400 HIV-negative high-risk PWUD enrolled in a community-based methadone maintenance treatment who reported drug- and/or sex-related HIV risk behaviors in the past 6-months. Analyses revealed support for the IMB model as PrEP-related behavioral skills were found to mediate the influence of PrEP-related information and motivation on willingness to use PrEP. The results provide evidence as to the utility of the IMB model to increase willingness to use PrEP among high-risk PWUD. It therefore makes an important contribution to our understanding of the applicability of theoretically-grounded models of willingness to use PrEP among high-risk PWUD, who are one of the key risk populations who could benefit from the use of PrEP.

  20. Buoy Technology survey USCG Buoy Development Review

    DTIC Science & Technology

    1990-10-01

    object of this report. This report was directed and sponsored by the Coast Guard Research and Development Center. This report does not constitute a ...offices, buoy tender crews, industrial facilities and with a limited number of buoy manufacturers in the United States. The USCG buoy development since...1962 is established in the form of twenty seven Project Summaries and supplemented with a comprehensive "Buoy Technology Bibliography" and a

  1. PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers

    PubMed Central

    Zablotska, Iryna; Grulich, Andrew E; Phanuphak, Nittaya; Anand, Tarandeep; Janyam, Surang; Poonkasetwattana, Midnight; Baggaley, Rachel; van Griensven, Frits; Lo, Ying-Ru

    2016-01-01

    Introduction HIV epidemics in the Asia-Pacific region are concentrated among men who have sex with men (MSM) and other key populations. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention intervention and could be a potential game changer in the region. We discuss the progress towards PrEP implementation in the Asia-Pacific region, including opportunities and barriers. Discussion Awareness about PrEP in the Asia-Pacific is still low and so are its levels of use. A high proportion of MSM who are aware of PrEP are willing to use it. Key PrEP implementation barriers include poor knowledge about PrEP, limited access to PrEP, weak or non-existent HIV prevention programmes for MSM and other key populations, high cost of PrEP, stigma and discrimination against key populations and restrictive laws in some countries. Only several clinical trials, demonstration projects and a few larger-scale implementation studies have been implemented so far in Thailand and Australia. However, novel approaches to PrEP implementation have emerged: researcher-, facility- and community-led models of care, with PrEP services for fee and for free. The WHO consolidated guidelines on HIV testing, treatment and prevention call for an expanded access to PrEP worldwide and have provided guidance on PrEP implementation in the region. Some countries like Australia have released national PrEP guidelines. There are growing community leadership and consultation processes to initiate PrEP implementation in Asia and the Pacific. Conclusions Countries of the Asia-Pacific region will benefit from adding PrEP to their HIV prevention packages, but for many this is a critical step that requires resourcing. Having an impact on the HIV epidemic requires investment. The next years should see the region transitioning from limited PrEP implementation projects to growing access to PrEP and expansion of HIV prevention programmes. PMID:27760688

  2. United States family planning providers' knowledge of and attitudes towards preexposure prophylaxis for HIV prevention: a national survey.

    PubMed

    Seidman, Dominika; Carlson, Kimberly; Weber, Shannon; Witt, Jacki; Kelly, Patricia J

    2016-05-01

    The Centers for Disease Control and Prevention defines HIV prevention as a core family planning service. The HIV community identified family planning visits as key encounters for women to access preexposure prophylaxis (PrEP) for HIV prevention. No studies explore US family planning providers' knowledge of and attitudes towards PrEP. We conducted a national survey of clinicians to understand barriers and facilitators to PrEP implementation in family planning. Family planning providers recruited via website postings, national meetings, and email completed an anonymous survey in 2015. Descriptive statistics were performed. Among 604 respondents, 495 were eligible for analysis and 342 were potential PrEP prescribers (physicians, nurse practitioners, midwives or physicians assistants). Among potential prescribers, 38% correctly defined PrEP [95% confidence interval (CI): 32.5-42.8], 37% correctly stated the efficacy of PrEP (95% CI: 32.0-42.4), and 36% chose the correct HIV test after a recent exposure (95% CI: 30.6-40.8). Characteristics of those who answered knowledge questions correctly included age less than 35 years, practicing in the Northeast or West, routinely offering HIV testing, providing rectal sexually transmitted infection screening or having seen any PrEP guidelines. Even among providers in the Northeast and West, the proportion of respondents answering questions correctly was less than 50%. Thirty-six percent of respondents had seen any PrEP guidelines. Providers identified lack of training as the main barrier to PrEP implementation; 87% wanted PrEP education. To offer comprehensive HIV prevention services, family planning providers urgently need training on PrEP and HIV testing. US family planning providers have limited knowledge about HIV PrEP and HIV testing, and report lack of provider training as the main barrier to PrEP provision. Provider education is needed to ensure that family planning clients access comprehensive HIV prevention methods

  3. Developing an Oropharyngeal Cancer (OPC) Knowledge and Behaviors Survey

    PubMed Central

    Dodd, Virginia J.; Riley, Joseph L.; Logan, Henrietta L.

    2012-01-01

    Objectives To use the community participation research model to (1) develop a survey assessing knowledge about mouth and throat cancer and (2) field test and establish test-retest reliability with newly developed instrument. Methods Cognitive interviews with primarily rural African American adults to assess their perception and interpretation of survey items. Test-retest reliability was established with a racially diverse rural population. Results Test-retest reliabilities ranged from .79 to .40 for screening awareness and .74 to .19 for knowledge. Coefficients increased for composite scores. Conclusion Community participation methodology provided a culturally appropriate survey instrument that demonstrated acceptable levels of reliability. PMID:22584087

  4. Bacteria on External Fixators: Which Prep is Best?

    DTIC Science & Technology

    2012-01-01

    Wenke, PhD, and Joseph R. Hsu, MD, San Antonio, Texas BACKGROUND: There are no established guidelines for the surgical prep of an external fixator in...were then randomized into four treatment groups: chlorhexidine- gluconate (CHG) (4%) scrub , CHG (4%) spray, povidone-iodine (PI) (10%) scrub , and PI...reimaged. Spatial distribution of bacteria and total bacteria counts were compared. RESULTS: There was a similar reduction in bacteria after surgical

  5. Time-Dependent Effect of Chlorhexidine Surgical Prep

    DTIC Science & Technology

    2011-10-15

    Time-dependent effect of chlorhexidine surgical prep D.J. Stinner*, C.A. Krueger, B.D. Masini, J.C. Wenke United States Army Institute of Surgical ...2011 by J.A. Child Available online 15 October 2011 Keywords: Chlorhexidine Surgical site infection s u m m a r y Despite continued advances in...preoperative preventive measures and aseptic technique, surgical site infections remain a problem. The purpose of this study was to evaluate the time

  6. Fuel cells: a survey of current developments

    NASA Astrophysics Data System (ADS)

    Cropper, Mark A. J.; Geiger, Stefan; Jollie, David M.

    Since the first practical uses of fuel cells were developed, it has become clear that they could find use in many products over a wide power range of milliwatts to tens of megawatts. Throughout the 1990s, and later, there has been significant work carried out on adapting the various different fuel cell technologies for use in targetted consumer and industrial applications. This paper discusses these developments and gives details on the specific market segments for providing power to vehicles, portable devices and large- and small-scale stationary power generation.

  7. Survey of Instructional Development Models. Third Edition.

    ERIC Educational Resources Information Center

    Gustafson, Kent L.; Branch, Robert Maribe

    This ERIC (Educational Resources Information Center) monograph updates and expands upon earlier ERIC publications on the topic of instructional development (ID) models. This monograph presents a brief history of ID models, describes a taxonomy for classifying them, provides examples from each of the categories in the taxonomy, and describes trends…

  8. Protocol for an open-label, single-arm trial of HIV pre-exposure prophylaxis (PrEP) among people at high risk of HIV infection: the NSW Demonstration Project PRELUDE

    PubMed Central

    Vaccher, S; Grulich, A; McAllister, J; Templeton, D J; Bloch, M; McNulty, A; Holden, J; Poynten, I M; Prestage, G; Zablotska, I

    2016-01-01

    Introduction Despite a number of HIV prevention strategies, the number of new HIV infections remains high. In Australia, over three-quarters of new HIV diagnoses are in gay and bisexual men (GBM). Pre-exposure prophylaxis (PrEP) has been shown to be effective at preventing new HIV infections in several randomised trials. The PRELUDE study aims to evaluate the implementation of PrEP in healthcare settings in New South Wales (NSW), Australia, among a sample of high-risk adults. Methods and analysis PRELUDE is an ongoing open-label, single-arm demonstration project, conducted in public and private clinics across NSW, Australia. Enrolment began in November 2014. The study is designed for 300 high-risk participants—mainly GBM and heterosexual women. Participants receive daily oral PrEP, composed of emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF), for up to 2.5 years. Quarterly study visits include testing for HIV and sexually transmitted infections (STIs), assessment of ongoing eligibility and side effects, and self-reported adherence. Following each study visit, online behavioural surveys are administered to collect information on medication adherence, risk behaviours and attitudes. Blood samples will be collected in a subset of patients 1, 6 and 12 months after PrEP initiation to measure FTC/TDF concentrations. Analyses using longitudinal regression models will focus on feasibility, adherence, safety, tolerability and effects of PrEP on behaviour. This study will inform PrEP policy and guide the implementation of PrEP in Australia in people at high risk of HIV. Ethics and dissemination The study will be conducted in accordance with the Declaration of Helsinki. All patients will provide written informed consent prior to participation in the study. Publications relating to each of the primary end points will be gradually released after 12 months of follow-up is complete. Trial registration number NCT02206555; Pre-results. PMID:27324719

  9. Society of Pediatric Psychology Workforce Survey: Development of Survey Methods, Sample Characteristics, and Lessons Learned

    PubMed Central

    Wysocki, Tim; Brosig, Cheryl L.; Hilliard, Marisa E.

    2016-01-01

    There are few detailed workforce studies of specialty fields within professional psychology, and none have been reported for pediatric psychology since 2006. Availability of such data could facilitate more-informed decision making by students and trainees, psychologists pursuing employment opportunities, and psychologists involved in employment or compensation negotiations. This article describes the work of a task force of the American Psychological Association (APA) Division 54 (Society of Pediatric Psychology) in the design, construction, pretesting, distribution, and data management for the Society of Pediatric Psychology (SPP) Workforce Survey. The 18-member task force was established to design and implement a workforce survey that balanced needs for breadth, clarity, brevity, and protection of confidentiality. The survey solicits information about demographic characteristics; training, licensure and certifications; employment settings, responsibilities, and productivity metrics; compensation; and employment satisfaction. A survey link was distributed via e-mail to full members of the SPP in June 2015. A total of 404 members (32.3% return rate) completed the survey. This article focuses on the development, methodology, and respondent characteristics for this 1st administration of the workforce survey. Separate articles will report detailed analyses of the survey results such as compensation and work satisfaction. Future distributions of the survey will enable compilation of a longitudinal database to track changes in the profession. SPP members and others may propose additional analyses of these data. This work may provide guidance to other groups of specialized psychologists who may wish to implement similar initiatives. PMID:28066693

  10. Society of Pediatric Psychology Workforce Survey: Development of Survey Methods, Sample Characteristics, and Lessons Learned.

    PubMed

    Wysocki, Tim; Brosig, Cheryl L; Hilliard, Marisa E

    2016-03-01

    There are few detailed workforce studies of specialty fields within professional psychology, and none have been reported for pediatric psychology since 2006. Availability of such data could facilitate more-informed decision making by students and trainees, psychologists pursuing employment opportunities, and psychologists involved in employment or compensation negotiations. This article describes the work of a task force of the American Psychological Association (APA) Division 54 (Society of Pediatric Psychology) in the design, construction, pretesting, distribution, and data management for the Society of Pediatric Psychology (SPP) Workforce Survey. The 18-member task force was established to design and implement a workforce survey that balanced needs for breadth, clarity, brevity, and protection of confidentiality. The survey solicits information about demographic characteristics; training, licensure and certifications; employment settings, responsibilities, and productivity metrics; compensation; and employment satisfaction. A survey link was distributed via e-mail to full members of the SPP in June 2015. A total of 404 members (32.3% return rate) completed the survey. This article focuses on the development, methodology, and respondent characteristics for this 1st administration of the workforce survey. Separate articles will report detailed analyses of the survey results such as compensation and work satisfaction. Future distributions of the survey will enable compilation of a longitudinal database to track changes in the profession. SPP members and others may propose additional analyses of these data. This work may provide guidance to other groups of specialized psychologists who may wish to implement similar initiatives.

  11. Perception Survey. Staff and Faculty Development Programs.

    DTIC Science & Technology

    1984-11-01

    a problem does exist, and if so, the nature and cause of the problem. (2) Staff and Faculty Development Division has responsi- bility for the overall...ability to perform the same 20 staff-related tasks that were rated by their supervisors. The following scale * was used: Their raings forNted tasks frare...much emphasis on stopping at just task, conditions , and standard. Of course we need to be concerned with these, but we must revitalize the thinking

  12. Survey of developing electronic photography standards

    NASA Astrophysics Data System (ADS)

    Holm, Jack M.

    1996-01-01

    The ISO TC42/WG18 and ANSI/NAPM IT10 Technical Committees are developing the following standards related to electronic still photography: ISO 12231 -- Glossary of technical terms; ISO 12232 -- Determination of ISO speed; ISO 12233 -- Resolution measurements; ISO 12234 -- Removable memory; and ISO 14524 -- OECF measurement methods. ISO 12231 is at the DIS stage, ISO 12234 and 14524 are at the CD stage, and ISO 12232 and 12233 will most likely reach the CD stage within a year. Since most of these documents are approaching final form, it is useful to examine them in some detail. Presented here are summaries of the contents of these standards accompanied by comments on their application and state of development. These standards are viewed from a broad digital photography perspective, and placed in context with other work in this area. Significant research has been accomplished in these committees, and is discussed in relation to fundamental imaging issues. Also discussed are future projects and areas where standardization is needed but little has been accomplished. In addition to providing a forum for the development of standards, technical committees are an important avenue for interaction between companies, user groups, and the government. Such avenues can have a great impact on emerging technologies.

  13. 2 + 2 Tech Prep Early Childhood Professions I and II Curriculum Guide: A Four Year Articulated Program for Secondary and Postsecondary Students.

    ERIC Educational Resources Information Center

    Patton, Mary Martin; Harriman, Marilyn Williams

    The 2 + 2 Tech Prep Early Childhood Professions I and II curriculum guides, developed through funding from the Carl D. Perkins Education Act, are designed for students entering the first and second years of the program. They are the first and second in a series of courses that systematically expand students' knowledge, skills application, and…

  14. Survey and analysis of federally developed technology

    SciTech Connect

    Reed, J.E.; Conrad, J.L.

    1983-02-01

    The methodology and results of a test effort to determine whether there exist unexpected opportunities for the direct transfer of technologies from federal laboratories to industry are presented. Specifically, the latest results of six federal laboratories with potential application in the pulp and paper industry, particularly those results applicable to improving energy productivity, were evaluated, cataloged, and distributed to industry representatives to gauge their reaction. The principal methodological steps in this effort were the development of a taxonomy of the pulp and paper industry, identification of industry needs and laboratory capabilities, laboratory visits, review of technology findings with industry, and evaluation and compilation of industry responses.

  15. IPPF discusses unmet needs and adolescents at PrepCom III.

    PubMed

    1994-04-01

    The third preparatory committee (PrepCom III) for the September 1994 International Conference on Population and Development will be held in New York during April 4-22. Nongovernmental organization (NGO) representatives will take the opportunity to lobby and brief government delegates on draft documents at this final such meeting before the conference convenes in September. Preparations thus far point to an increasing international recognition of individual needs. The International Planned Parenthood Federation (IPPF) hopes PrepCom III will ensure that this recognition is reflected in the final recommendations to the conference and that government delegates work with NGOs to provide an appropriate framework for Cairo. A variety of IPPF and FPA staff will take part in the government and NGO forums, with IPPF Secretary General Halfdan Mahler addressing the opening session. On April 5, Dr. Mahler will release the new IPPF report on adolescent sexuality, Understanding Adolescents, highlighting the negative consequences of ignoring the sexual and reproductive health needs of young people. Programs need to treat young people with respect and dignity. The report profiles some programs which have been successful in locales around the world. IPPF hopes to convince decision makers that their political and financial commitment is needed to secure the health and well-being of today's and tomorrow's young people. Another report on the unmet need for family planning services among marginalized populations in Uganda, El Salvador, Ghana, Palestine, and the Philippines will be presented at a reception hosted by Dr. Sai and Dr. Mahler.

  16. Partner Disclosure of PrEP Use and Undetectable Viral Load on Geosocial Networking Apps: Frequency of Disclosure and Decisions About Condomless Sex.

    PubMed

    Newcomb, Michael E; Mongrella, Melissa C; Weis, Benjamin; McMillen, Samuel J; Mustanski, Brian

    2016-02-01

    Recent advances in biomedical prevention strategies, including pre-exposure prophylaxis (PrEP) and achieving an undetectable viral load (UVL) among HIV-infected persons, show promise in curbing the rising incidence of HIV among men who have sex with men (MSM) in the United States. This mixed-methods study aimed to investigate the frequency with which MSM encounter potential sex partners on geosocial networking apps who disclose biomedical prevention use, and how MSM make decisions about condom use after these disclosures. Participants were recruited through advertisements placed on a large geosocial networking app for MSM. A total of 668 and 727 participants, respectively, responded to questionnaires assessing partner disclosure of PrEP use and UVL. Each questionnaire included an open-ended item assessing reasons for condomless anal sex (CAS) with partners using biomedical prevention. Across both surveys, most respondents encountered potential sex partners who disclosed PrEP use or UVL, and the majority of those who met up with these partners engaged in CAS at least once. Qualitative analyses found that most participants who reported CAS did so after making a calculated risk about HIV transmission. We also describe a novel risk reduction strategy, "biomed-matching," or having CAS only when both individuals use PrEP or have UVL. We report serostatus differences in both quantitative and qualitative findings. Disclosure of PrEP use and UVL is not uncommon among MSM. Many MSM make accurate appraisals of the risks of CAS with biomedical prevention, and mobile apps may aid with disclosing biomedical prevention use.

  17. Partner Disclosure of PrEP Use and Undetectable Viral Load on Geosocial Networking Apps: Frequency of Disclosure and Decisions about Condomless Sex

    PubMed Central

    Newcomb, Michael E.; Mongrella, Melissa C.; Weis, Benjamin; McMillen, Samuel J.; Mustanski, Brian

    2015-01-01

    Background Recent advances in biomedical prevention strategies, including pre-exposure prophylaxis (PrEP) and achieving an undetectable viral load (UVL) among HIV-infected persons, show promise in curbing the rising incidence of HIV among men who have sex with men (MSM) in the United States. This mixed methods study aimed to investigate the frequency with which MSM encounter potential sex partners on geosocial networking apps who disclose biomedical prevention use, and how MSM make decisions about condom use after these disclosures. Method Participants were recruited via adverstiments placed on a large geosocial networking app for MSM. A total of 668 and 727 participants, respectively, responded to questionnaires assessing partner disclosure of PrEP use and UVL. Each questionnaire included an open-ended item assessing reasons for condomless anal sex (CAS) with partners using biomedical prevention. Results Across both surveys, a majority of respondents encountered potential sex partners who disclosed PrEP use or UVL, and the majority of those who met up with these partners engaged in CAS at least once. Qualitative analyses found that most participants who reported CAS did so after making a calculated risk about HIV transmission. We also describe a novel risk reduction strategy, “biomed-matching,” or having CAS only when both individuals use PrEP or have UVL. We report serostatus differences in both quantitative and qualitative findings. Conclusions Disclosure of PrEP use and UVL is not uncommon among MSM. Many MSM make accurate appraisals of the risks of CAS with biomedical prevention, and mobile apps may aid with disclosing biomedical prevention use. PMID:26761520

  18. Development and validation of the primary care team dynamics survey.

    PubMed

    Song, Hummy; Chien, Alyna T; Fisher, Josephine; Martin, Julia; Peters, Antoinette S; Hacker, Karen; Rosenthal, Meredith B; Singer, Sara J

    2015-06-01

    To develop and validate a survey instrument designed to measure team dynamics in primary care. We studied 1,080 physician and nonphysician health care professionals working at 18 primary care practices participating in a learning collaborative aimed at improving team-based care. We developed a conceptual model and administered a cross-sectional survey addressing team dynamics, and we assessed reliability and discriminant validity of survey factors and the overall survey's goodness-of-fit using structural equation modeling. We administered the survey between September 2012 and March 2013. Overall response rate was 68 percent (732 respondents). Results support a seven-factor model of team dynamics, suggesting that conditions for team effectiveness, shared understanding, and three supportive processes are associated with acting and feeling like a team and, in turn, perceived team effectiveness. This model demonstrated adequate fit (goodness-of-fit index: 0.91), scale reliability (Cronbach's alphas: 0.71-0.91), and discriminant validity (average factor correlations: 0.49). It is possible to measure primary care team dynamics reliably using a 29-item survey. This survey may be used in ambulatory settings to study teamwork and explore the effect of efforts to improve team-based care. Future studies should demonstrate the importance of team dynamics for markers of team effectiveness (e.g., work satisfaction, care quality, clinical outcomes). © Health Research and Educational Trust.

  19. The development of the Patient Expectations of Shoulder Surgery survey.

    PubMed

    Koorevaar, Rinco C T; Haanstra, Tsjitske; Van't Riet, Esther; Lambers Heerspink, Okke F O; Bulstra, Sjoerd K

    2017-06-07

    Patient satisfaction after a surgical procedure is dependent on meeting preoperative expectations. There is currently no patient expectations survey available for patients undergoing shoulder surgery that is validated, reliable, and easy to use in daily practice. The aim of this study was to develop a Patient Expectations of Shoulder Surgery (PESS) survey. In 315 patients, answers to an open-ended question about patient expectations were collected before shoulder surgery to develop the PESS survey. Patients' expectations of the PESS survey were associated with clinical outcome (change of Disabilities of the Arm, Shoulder, and Hand score). Content validity was assessed by a panel of 10 patients scheduled for shoulder surgery, and test-retest reliability was evaluated. Six items were included in the PESS survey: pain relief, improved range of motion, improved ability to perform daily activities, improved ability to perform work, improved ability to participate in recreational activities and sports, and stop shoulder from dislocating. Three of the 6 expectations were significantly associated with clinical outcome after shoulder surgery. Test-retest reliability was high with an intraclass correlation coefficient of 0.52-0.92. The PESS survey is a valid and reliable survey that can be used in future clinical research and in daily orthopedic practice. We believe that the preoperative evaluation of patient expectations should be a standard procedure before shoulder surgery. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

  20. Development and Validation of the Primary Care Team Dynamics Survey

    PubMed Central

    Song, Hummy; Chien, Alyna T; Fisher, Josephine; Martin, Julia; Peters, Antoinette S; Hacker, Karen; Rosenthal, Meredith B; Singer, Sara J

    2015-01-01

    Objective To develop and validate a survey instrument designed to measure team dynamics in primary care. Data Sources/Study Setting We studied 1,080 physician and nonphysician health care professionals working at 18 primary care practices participating in a learning collaborative aimed at improving team-based care. Study Design We developed a conceptual model and administered a cross-sectional survey addressing team dynamics, and we assessed reliability and discriminant validity of survey factors and the overall survey's goodness-of-fit using structural equation modeling. Data Collection We administered the survey between September 2012 and March 2013. Principal Findings Overall response rate was 68 percent (732 respondents). Results support a seven-factor model of team dynamics, suggesting that conditions for team effectiveness, shared understanding, and three supportive processes are associated with acting and feeling like a team and, in turn, perceived team effectiveness. This model demonstrated adequate fit (goodness-of-fit index: 0.91), scale reliability (Cronbach's alphas: 0.71–0.91), and discriminant validity (average factor correlations: 0.49). Conclusions It is possible to measure primary care team dynamics reliably using a 29-item survey. This survey may be used in ambulatory settings to study teamwork and explore the effect of efforts to improve team-based care. Future studies should demonstrate the importance of team dynamics for markers of team effectiveness (e.g., work satisfaction, care quality, clinical outcomes). PMID:25423886

  1. Development and validation of a Housing First fidelity survey.

    PubMed

    Gilmer, Todd P; Stefancic, Ana; Sklar, Marisa; Tsemberis, Sam

    2013-09-01

    Programs that use the Housing First model are being implemented throughout the United States and internationally. The authors describe the development and validation of a Housing First fidelity survey. A 46-item survey was developed to measure fidelity across five domains: housing process and structure, separation of housing and services, service philosophy, service array, and team structure. The survey was administered to staff and clients of 93 supported-housing programs in California. Exploratory and confirmatory factor analyses were used to identify the items and model structure that best fit the data. Sixteen items were retained in a two-factor model, one related to approach to housing, separation of housing and services, and service philosophy and one related to service array and team structure. Our survey mapped program practices by using a common metric that captured variation in fidelity to Housing First across a large-scale implementation of supported-housing programs.

  2. Development and Implementation of Culturally Tailored Offline Mobile Health Surveys

    PubMed Central

    2016-01-01

    Background In low and middle income countries (LMICs), and other areas with low resources and unreliable access to the Internet, understanding the emerging best practices for the implementation of new mobile health (mHealth) technologies is needed for efficient and secure data management and for informing public health researchers. Innovations in mHealth technology can improve on previous methods, and dissemination of project development details and lessons learned during implementation are needed to provide lessons learned to stakeholders in both the United States and LMIC settings. Objective The aims of this paper are to share implementation strategies and lessons learned from the development and implementation stages of two survey research projects using offline mobile technology, and to inform and prepare public health researchers and practitioners to implement new mobile technologies in survey research projects in LMICs. Methods In 2015, two survey research projects were developed and piloted in Puerto Rico and pre-tested in Costa Rica to collect face-to-face data, get formative evaluation feedback, and to test the feasibility of an offline mobile data collection process. Fieldwork in each setting involved survey development, back translation with cultural tailoring, ethical review and approvals, data collector training, and piloting survey implementation on mobile tablets. Results Critical processes and workflows for survey research projects in low resource settings were identified and implemented. This included developing a secure mobile data platform tailored to each survey, establishing user accessibility, and training and eliciting feedback from data collectors and on-site LMIC project partners. Conclusions Formative and process evaluation strategies are necessary and useful for the development and implementation of survey research projects using emerging mHealth technologies in LMICs and other low resource settings. Lessons learned include: (1) plan

  3. Reliability worth assessment in a developing country - residential survey results

    SciTech Connect

    Billinton, R.; Pandey, M.

    1999-11-01

    This paper presents the results of a residential customer survey conducted in service areas of the Nepal Integrated Electric Power System (NPS). The objective was to determine the power interruption costs incurred by the residential customers of a developing country, and extend the customer survey approach to reliability worth evaluation in a developing environment. Interruption cost estimates were obtained using in-person interviews with 944 sample customers. The results indicate the implications of service reliability to residential customers of Nepal, and show that reliability worth evaluation in a developing country is both possible and practical.

  4. Use of an HIV-risk screening tool to identify optimal candidates for PrEP scale-up among men who have sex with men in Toronto, Canada: disconnect between objective and subjective HIV risk.

    PubMed

    Wilton, James; Kain, Taylor; Fowler, Shawn; Hart, Trevor A; Grennan, Troy; Maxwell, John; Tan, Darrell Hs

    2016-01-01

    Identifying appropriate pre-exposure prophylaxis (PrEP) candidates is a challenge in planning for the safe and effective roll-out of this strategy. We explored the use of a validated HIV risk screening tool, HIV Incidence Risk Index for Men who have Sex with Men (HIRI-MSM), to identify "optimal" candidates among MSM testing at a busy sexual health clinic's community testing sites in Toronto, Canada. Between November 2014 and April 2015, we surveyed MSM undergoing anonymous HIV testing at community testing sites in Toronto, Canada, to quantify "optimal" candidates for scaling up PrEP roll-out, defined as being at high objective HIV risk (scoring ≥10 on the HIRI-MSM), perceiving oneself at moderate-to-high HIV risk and being willing to use PrEP. Cascades were constructed to identify barriers to broader PrEP uptake. The association between HIRI-MSM score and both willingness to use PrEP and perceived HIV risk were explored in separate multivariable logistic regression analyses. Of 420 respondents, 64.4% were objectively at high risk, 52.5% were willing to use PrEP and 27.2% perceived themselves at moderate-to-high HIV risk. Only 16.4% were "optimal" candidates. Higher HIRI-MSM scores were positively associated with both willingness to use PrEP (aOR=1.7 per 10 score increase, 95%CI=1.3-2.2) and moderate-to-high perceived HIV risk (aOR=1.7 per 10 score increase, 95%CI=1.2-2.3). The proportion of men who were "optimal" candidates increased to 42.9% when the objective HIV risk cut-off was changed to top quartile of HIRI-MSM scores (≥26). In our full cascade, a very low proportion (5.3%) of MSM surveyed could potentially benefit from PrEP under current conditions. The greatest barrier in the cascade was low perception of HIV risk among high-risk men, but considerable numbers were also lost in downstream cascade steps. Of men at high objective HIV risk, 68.3% did not perceive themselves to be at moderate-to-high HIV risk, 23.6% were unaware of PrEP, 40.1% were not

  5. Use of an HIV-risk screening tool to identify optimal candidates for PrEP scale-up among men who have sex with men in Toronto, Canada: disconnect between objective and subjective HIV risk

    PubMed Central

    Wilton, James; Kain, Taylor; Fowler, Shawn; Hart, Trevor A; Grennan, Troy; Maxwell, John; Tan, Darrell HS

    2016-01-01

    Introduction Identifying appropriate pre-exposure prophylaxis (PrEP) candidates is a challenge in planning for the safe and effective roll-out of this strategy. We explored the use of a validated HIV risk screening tool, HIV Incidence Risk Index for Men who have Sex with Men (HIRI-MSM), to identify “optimal” candidates among MSM testing at a busy sexual health clinic's community testing sites in Toronto, Canada. Methods Between November 2014 and April 2015, we surveyed MSM undergoing anonymous HIV testing at community testing sites in Toronto, Canada, to quantify “optimal” candidates for scaling up PrEP roll-out, defined as being at high objective HIV risk (scoring ≥10 on the HIRI-MSM), perceiving oneself at moderate-to-high HIV risk and being willing to use PrEP. Cascades were constructed to identify barriers to broader PrEP uptake. The association between HIRI-MSM score and both willingness to use PrEP and perceived HIV risk were explored in separate multivariable logistic regression analyses. Results Of 420 respondents, 64.4% were objectively at high risk, 52.5% were willing to use PrEP and 27.2% perceived themselves at moderate-to-high HIV risk. Only 16.4% were “optimal” candidates. Higher HIRI-MSM scores were positively associated with both willingness to use PrEP (aOR=1.7 per 10 score increase, 95%CI=1.3–2.2) and moderate-to-high perceived HIV risk (aOR=1.7 per 10 score increase, 95%CI=1.2–2.3). The proportion of men who were “optimal” candidates increased to 42.9% when the objective HIV risk cut-off was changed to top quartile of HIRI-MSM scores (≥26). In our full cascade, a very low proportion (5.3%) of MSM surveyed could potentially benefit from PrEP under current conditions. The greatest barrier in the cascade was low perception of HIV risk among high-risk men, but considerable numbers were also lost in downstream cascade steps. Of men at high objective HIV risk, 68.3% did not perceive themselves to be at moderate-to-high HIV risk

  6. Cognitive interviewing in risk minimization survey development: patient and healthcare professional surveys.

    PubMed

    DiBenedetti, Dana B; Price, Mark A; Andrews, Elizabeth B

    2013-07-01

    Risk minimization programs are often required for selected drugs and other products to ensure that the benefits of these prescription products outweigh their risks. Regulators in the USA and Europe have recently called for more rigorous standards in developing measures for risk minimization program assessment. Cognitive pretesting interviews are a critical step in the development of survey instruments used to evaluate patients' and healthcare professionals' knowledge and behaviors associated with the safe use of products requiring a risk minimization program. This article is intended as a guide for the researcher who is charged with the development of survey instruments used in these programs and focuses on the role of cognitive pretesting interviews in successful survey instrument design, data analysis and interpretation.

  7. Large Scale Survey Data in Career Development Research

    ERIC Educational Resources Information Center

    Diemer, Matthew A.

    2008-01-01

    Large scale survey datasets have been underutilized but offer numerous advantages for career development scholars, as they contain numerous career development constructs with large and diverse samples that are followed longitudinally. Constructs such as work salience, vocational expectations, educational expectations, work satisfaction, and…

  8. Survey of advanced-heat-pump developments for space conditioning

    SciTech Connect

    Fairchild, P.D.

    1981-01-01

    A survey of heat pump projects with special emphasis on those supported by DOE, EPRI, and the Gas Research Institute is presented. Some historical notes on heat pump development are discussed. Market and equipment trends, well water and ground-coupled heat pumps, heat-actuated heat pump development, and international interest in heat pumps are also discussed. 30 references.

  9. Development of the Australasian Survey of Student Engagement (AUSSE)

    ERIC Educational Resources Information Center

    Coates, Hamish

    2010-01-01

    Student learning and development are the core business of the academy, yet until recently Australian and New Zealand universities lacked data on students' engagement in effective educational practices. This paper reports the foundations and development of the Australasian Survey of Student Engagement (AUSSE)--the largest educationally focused…

  10. Development of the Fear Survey for Adults with Mental Retardation

    ERIC Educational Resources Information Center

    Ramirez, Sylvia Z.; Lukenbill, James F.

    2007-01-01

    This paper describes the development of the fear survey for adults with mental retardation (FSAMR) and provides initial evidence of its psychometric properties. The FSAMR was designed to be sensitive to the assessment needs of individuals with mental retardation. The items were developed through open-ended interviews, a review of existing…

  11. Large Scale Survey Data in Career Development Research

    ERIC Educational Resources Information Center

    Diemer, Matthew A.

    2008-01-01

    Large scale survey datasets have been underutilized but offer numerous advantages for career development scholars, as they contain numerous career development constructs with large and diverse samples that are followed longitudinally. Constructs such as work salience, vocational expectations, educational expectations, work satisfaction, and…

  12. Development of the Australasian Survey of Student Engagement (AUSSE)

    ERIC Educational Resources Information Center

    Coates, Hamish

    2010-01-01

    Student learning and development are the core business of the academy, yet until recently Australian and New Zealand universities lacked data on students' engagement in effective educational practices. This paper reports the foundations and development of the Australasian Survey of Student Engagement (AUSSE)--the largest educationally focused…

  13. The parenting responsibility and emotional preparedness (PREP) screening tool: a 3-item screen that identifies teen mothers at high risk for nonoptimal parenting.

    PubMed

    Lanzi, Robin Gaines; Ramey, Sharon Landesman; Bert, Shannon Carothers

    2012-08-01

    OBJECTIVE To test the ability of a 3-item screening tool (Parenting Responsibility and Emotional Preparedness [PREP]) to detect adolescent mothers at elevated risk for nonoptimal parenting and poor child development outcomes at 2 years of age. DESIGN A 4-site prospective cohort study conducted from December 2001 to August 2007 of adolescent mothers recruited in the third trimester of pregnancy and followed up at 4, 8, 18, and 24 months post partum. SETTING Community clinics and home settings in Birmingham, Alabama; Kansas City, Kansas and Missouri; South Bend, Indiana; and Washington, DC. PARTICIPANTS A total of 270 first-time adolescent mothers (aged 15-19 years) and their infants (birth to 2 years of age). MAIN EXPOSURES Naturalistic observations of parent-child interactions and quality of home environment during the first 2 years of life. OUTCOME MEASURES Maternal mental health and cognitive indicators, positive mother-child interactions, quality of home environment, child social-emotional development, and child cognitive development (Bayley scales). RESULTS PREP scores identified adolescent mothers with significantly elevated depressive symptoms and childhood trauma and lower scores of knowledge of infant development and maternal IQ. PREP predicted significantly lower quality of home environments and higher levels of nonoptimal mother-child interactions at 4, 8, and 18 months. PREP also predicted significantly lower child outcomes at 2 years of age for cognitive scores and higher levels of depressive and withdrawal symptoms and dysregulation and negative emotionality. CONCLUSIONS PREP is a low-cost, easily administered, nonstigmatizing screening tool that identifies adolescent mothers who self-recognize that they need help to meet their infants' social, emotional, and cognitive needs.

  14. Survey Methods for Educators: Collaborative Survey Development (Part 1 of 3). REL 2016-163

    ERIC Educational Resources Information Center

    Irwin, Clare W.; Stafford, Erin T.

    2016-01-01

    This guide describes a five-step collaborative process that educators can use with other educators, researchers, and content experts to write or adapt questions and develop surveys for education contexts. This process allows educators to leverage the expertise of individuals within and outside of their organization to ensure a high-quality survey…

  15. Urban Libraries Council Frequent Fast Facts Survey: Fund Raising and Financial Development Survey Results.

    ERIC Educational Resources Information Center

    Urban Libraries Council, Evanston, IL.

    This survey documents activities of Urban Libraries Council member libraries in the areas of fund raising and financial development, and gathers examples of library bylaws, policies on the use of private and general funds money, and policies on gifts. Questionnaires were sent to 89 member libraries in September 1993, and 63 were returned. Findings…

  16. Preparation for Raising Educational Performance (PREP) 1983-84. OEA Evaluation Report.

    ERIC Educational Resources Information Center

    New York City Board of Education, Brooklyn, NY. Office of Educational Evaluation.

    The 1983-84 Preparation for Raising Educational Performance (PREP) program was a theme-based program of instruction and supportive services for incoming ninth graders who are substantially below grade level in reading and mathematics. PREP was offered in 91 public high schools in New York City and provided services for nearly 12,000 students.…

  17. Charter Schools as Nation Builders: Democracy Prep and Civic Education. Policy Brief 4

    ERIC Educational Resources Information Center

    Lautzenheiser, Daniel; Kelly, Andrew P.

    2013-01-01

    This policy brief is the first in a series of in-depth case studies exploring how top-performing charter schools have incorporated civic learning in their school curriculum and school culture. This paper introduces Democracy Prep, a network of seven public charter schools with a civic mission at its core. Democracy Prep's founder and…

  18. The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity.

    PubMed

    Berthelsen, J; Zappavigna, V; Ferretti, E; Mavilio, F; Blasi, F

    1998-03-02

    The products of the mammalian Pbx and Drosophila exd genes are able to interact with Hox proteins specifically and to increase their DNA binding affinity and selectivity. In the accompanying paper we show that Pbx proteins exist as stable heterodimers with a novel homeodomain protein, Prep1. Here we show that Prep1-Pbx interaction presents novel structural features: it is independent of DNA binding and of the integrity of their respective homeodomains, and requires sequences in the N-terminal portions of both proteins. The Prep1-Pbx protein-protein interaction is essential for DNA-binding activity. Prep1-Pbx complexes are present in early mouse embryos at a time when Pbx is also interacting with Hox proteins. The use of different interaction surfaces could allow Pbx to interact with Prep1 and Hox proteins simultaneously. Indeed, we observe the formation of a ternary Prep1-Pbx1-HOXB1 complex on a HOXB1-responsive target in vitro. Interaction with Prep1 enhances the ability of the HOXB1-Pbx1 complex to activate transcription in a cooperative fashion from the same target. Our data suggest that Prep1 is an additional component in the transcriptional regulation by Hox proteins.

  19. SWATMOD-PREP: Graphical user interface for preparing coupled SWAT-modflow simulations

    USDA-ARS?s Scientific Manuscript database

    This paper presents SWATMOD-Prep, a graphical user interface that couples a SWAT watershed model with a MODFLOW groundwater flow model. The interface is based on a recently published SWAT-MODFLOW code that couples the models via mapping schemes. The spatial layout of SWATMOD-Prep guides the user t...

  20. On the Right Track: Southern Maryland Schools Revamp Their Curriculum around Tech Prep.

    ERIC Educational Resources Information Center

    Leftwich, Kathy

    1992-01-01

    In St. Mary's County (Maryland) schools' revamped curriculum, tech prep encompasses four clusters: applied business/management, applied engineering/mechanics, applied health/human services, and college prep. Career counselors help eighth graders choose a cluster and monitor their satisfaction with their choice, allowing them to change until junior…

  1. The Effect of Studying Tech Prep in High School and College Academic Performance

    ERIC Educational Resources Information Center

    Ray, Larry A.

    2011-01-01

    This study examined the academic performance of Tech Prep students (referred to as participants) in comparison to non-Tech Prep students (referred to as non-participants) entering a two-year community college from sixteen different high schools in Stark County, Ohio. This study provided a quantitative analysis of students' academic experiences to…

  2. Ethical public health issues for the use of informal PrEP.

    PubMed

    Brisson, Julien

    2017-09-03

    This article presents the phenomenon of the use of informal pre-exposure prophylaxis (PrEP), also known colloquially as 'wild PrEP'. The related ethical public health issues of the use of informal PrEP are discussed. From the approach of an ethical framework of risk reduction in public health, the main objective of this article is to encourage health-related practices and policies that do not stop the informal access to PrEP, but rather promote the wellbeing of users by providing them with the necessary knowledge and resources related to PrEP and HIV prevention (i.e. getting regularly tested for HIV if one is to take PrEP). As each country has its own policies with respect to PrEP and access to healthcare services, this article does not explore specific locations but rather highlights different global ethical key points on how to approach the use of informal PrEP with the goal of promoting HIV prevention among individuals at high risk for HIV infection.

  3. The ACCESS Consortium Tech Prep Summer Internship Report, August 1, 1993.

    ERIC Educational Resources Information Center

    Jolly, Mary Bouligny

    The 1993 Tech Prep Summer Internship Program at Delgado Community College (DCC), in New Orleans, was designed to provide work-related corporate experience to participating tech prep students and faculty. The 6-week program consisted of two components: actual employment with an area corporation 4 days a week and a classroom training program in…

  4. Hypothalamic prolyl endopeptidase (PREP) regulates pancreatic insulin and glucagon secretion in mice

    PubMed Central

    Kim, Jung Dae; Toda, Chitoku; D’Agostino, Giuseppe; Zeiss, Caroline J.; DiLeone, Ralph J.; Elsworth, John D.; Kibbey, Richard G.; Chan, Owen; Harvey, Brandon K.; Richie, Christopher T.; Savolainen, Mari; Myöhänen, Timo; Jeong, Jin Kwon; Diano, Sabrina

    2014-01-01

    Prolyl endopeptidase (PREP) has been implicated in neuronal functions. Here we report that hypothalamic PREP is predominantly expressed in the ventromedial nucleus (VMH), where it regulates glucose-induced neuronal activation. PREP knockdown mice (Prepgt/gt) exhibited glucose intolerance, decreased fasting insulin, increased fasting glucagon levels, and reduced glucose-induced insulin secretion compared with wild-type controls. Consistent with this, central infusion of a specific PREP inhibitor, S17092, impaired glucose tolerance and decreased insulin levels in wild-type mice. Arguing further for a central mode of action of PREP, isolated pancreatic islets showed no difference in glucose-induced insulin release between Prepgt/gt and wild-type mice. Furthermore, hyperinsulinemic euglycemic clamp studies showed no difference between Prepgt/gt and wild-type control mice. Central PREP regulation of insulin and glucagon secretion appears to be mediated by the autonomic nervous system because Prepgt/gt mice have elevated sympathetic outflow and norepinephrine levels in the pancreas, and propranolol treatment reversed glucose intolerance in these mice. Finally, re-expression of PREP by bilateral VMH injection of adeno-associated virus–PREP reversed the glucose-intolerant phenotype of the Prepgt/gt mice. Taken together, our results unmask a previously unknown player in central regulation of glucose metabolism and pancreatic function. PMID:25071172

  5. Making the Case for Tech Prep. New Perkins Act Boosts Secondary/Postsecondary Linkages.

    ERIC Educational Resources Information Center

    Scott, Robert W.

    1991-01-01

    Tech prep prepares people for technical careers by linking high school studies with community college coursework. The Pee Dee Tech Prep Program in North Carolina is a joint venture between the Richmond County Schools and Richmond Community College that connects essential skills learned in high school with occupation-specific skills taught in…

  6. Making the Case for Tech Prep. New Perkins Act Boosts Secondary/Postsecondary Linkages.

    ERIC Educational Resources Information Center

    Scott, Robert W.

    1991-01-01

    Tech prep prepares people for technical careers by linking high school studies with community college coursework. The Pee Dee Tech Prep Program in North Carolina is a joint venture between the Richmond County Schools and Richmond Community College that connects essential skills learned in high school with occupation-specific skills taught in…

  7. Bowel Prep Quality in Patients of Low Socioeconomic Status Undergoing Screening Colonoscopy with Patient Navigation

    ERIC Educational Resources Information Center

    Miller, Sarah Johanna; Itzkowitz, Steven H.; Shah, Brijen; Jandorf, Lina

    2016-01-01

    The effectiveness of colonoscopy is directly affected by the quality of the patient's bowel preparation. Patients with lower socioeconomic status (SES) are at increased risk of having suboptimal bowel prep quality. Patient navigators can play a key role in clarifying bowel prep instructions. The aim of the present study was to examine the quality…

  8. Charter Schools as Nation Builders: Democracy Prep and Civic Education. Policy Brief 4

    ERIC Educational Resources Information Center

    Lautzenheiser, Daniel; Kelly, Andrew P.

    2013-01-01

    This policy brief is the first in a series of in-depth case studies exploring how top-performing charter schools have incorporated civic learning in their school curriculum and school culture. This paper introduces Democracy Prep, a network of seven public charter schools with a civic mission at its core. Democracy Prep's founder and…

  9. Tech-Prep Competency Profiles within the Business/Computer Technologies.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document, which is designed for educators throughout Ohio who are involved in planning and/or delivering tech prep programs within the business/computer technologies cluster, discusses and presents tech prep competency profiles (TCPs) for 12 business/computer technology occupations. The first part of the document contains the following:…

  10. The Effect of Studying Tech Prep in High School and College Academic Performance

    ERIC Educational Resources Information Center

    Ray, Larry A.

    2011-01-01

    This study examined the academic performance of Tech Prep students (referred to as participants) in comparison to non-Tech Prep students (referred to as non-participants) entering a two-year community college from sixteen different high schools in Stark County, Ohio. This study provided a quantitative analysis of students' academic experiences to…

  11. Tech Prep Planning and Implementation Grants. 1992-1993 Final Report.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Community Colleges, Raleigh.

    An evaluation was conducted of tech prep, a focused, sequential 6-year course of study for high school and technical college students in North Carolina, using 19 criteria that were identified as being necessary to qualify for tech prep funding. Evaluation activities carried out by the North Carolina Departments of Public Instruction and Community…

  12. The Diverse Forms of Tech-Prep: Implementation Approaches in Ten Local Consortia.

    ERIC Educational Resources Information Center

    Hershey, Alan; And Others

    This document profiles the diverse approaches to tech-prep taken by 10 local districts across the United States. The tech-prep programs in the following cities are profiled: Dayton, Ohio; Dothan, Alabama; East Peoria, Illinois; Fresno, California; Gainesville, Florida; Hartford, Connecticut; Logan, West Virginia; Salem, Oregon; Springdale,…

  13. Tech-Prep Competency Profiles within the Business/Computer Technologies.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Center on Education and Training for Employment.

    This document, which is designed for educators throughout Ohio who are involved in planning and/or delivering tech prep programs within the business/computer technologies cluster, discusses and presents tech prep competency profiles (TCPs) for 12 business/computer technology occupations. The first part of the document contains the following:…

  14. 76 FR 51037 - Determination That Halflytely and Bisacodyl Tablets Bowel Prep Kit (Containing Two Bisacodyl...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-17

    ... (polyethylene glycol (PEG) 3350, sodium chloride, sodium bicarbonate, and potassium chloride for oral solution... applications (ANDAs) for bowel prep kits containing PEG-3350, sodium chloride, sodium bicarbonate, and... Bisacodyl Tablets Bowel Prep Kit (PEG- 3350, sodium chloride, sodium bicarbonate, and potassium chloride for...

  15. Making Tech Prep and School To Work Realistic Options in Transition Planning.

    ERIC Educational Resources Information Center

    Gugerty, John

    Information is provided on tech prep education programs, which are part of a restructuring movement that combines secondary and postsecondary programs to provide technical preparation in a field such as engineering technology, agriculture, health, or business. Information on the following topics is outlined: seven essential elements of tech prep;…

  16. A National Study of Research Priorities in Tech Prep Teacher Education.

    ERIC Educational Resources Information Center

    Farmer, Edgar I.

    A study was conducted in 1994 to identify, categorize, and prioritize research needs for improving teacher education related to the vocational education initiative of Tech Prep over the next 10 years. First, questionnaires were sent to experts in the field of Tech Prep, seeking a sample of needs and priorities. Responses were received from 33…

  17. Bowel Prep Quality in Patients of Low Socioeconomic Status Undergoing Screening Colonoscopy with Patient Navigation

    ERIC Educational Resources Information Center

    Miller, Sarah Johanna; Itzkowitz, Steven H.; Shah, Brijen; Jandorf, Lina

    2016-01-01

    The effectiveness of colonoscopy is directly affected by the quality of the patient's bowel preparation. Patients with lower socioeconomic status (SES) are at increased risk of having suboptimal bowel prep quality. Patient navigators can play a key role in clarifying bowel prep instructions. The aim of the present study was to examine the quality…

  18. Development of photogrammetry in the U.S. Geological Survey

    USGS Publications Warehouse

    Thompson, Morris M.

    1958-01-01

    Photogrammetry, the science or art of obtaining reliable measurements by means of photography, is now used extensively in topographic mapping. Precise photogrammetric plotting instruments now enable the map maker to extract from aerial photographs much.of the detailed information required for drawing the map that formerly was acquired by laborious ground surveys. Photography and photogrammetry have thus become essential components of all large mapping operations. The Geological Survey has played a leading role in the development of photogrammetric methods of mapping over a period of half a century. This role has been well documented in numerous articles appearing in technical publications during this time. It is the purpose of this circular to present, in brief form, the highlights of Geological Survey activities and developments in the field of photogrammetry, from pioneer efforts to present-day practice.

  19. Mechanism of Action of Prolyl Oligopeptidase (PREP) in Degenerative Brain Diseases: Has Peptidase Activity Only a Modulatory Role on the Interactions of PREP with Proteins?

    PubMed Central

    Männistö, Pekka T.; García-Horsman, J. Arturo

    2017-01-01

    In the aging brain, the correct balance of neural transmission and its regulation is of particular significance, and neuropeptides have a significant role. Prolyl oligopeptidase (PREP) is a protein highly expressed in brain, and evidence indicates that it is related to aging and in neurodegenration. Although PREP is regarded as a peptidase, the physiological substrates in the brain have not been defined, and after intense research, the molecular mechanisms where this protein is involved have not been defined. We propose that PREP functions as a regulator of other proteins though peptide gated direct interaction. We speculate that, at least in some processes where PREP has shown to be relevant, the peptidase activity is only a consequence of the interactions, and not the main physiological activity. PMID:28261087

  20. Peer-Mentored Preparedness (PM-Prep): A New Disaster Preparedness Program for Adults Living Independently in the Community

    ERIC Educational Resources Information Center

    Eisenman, David Paul; Bazzano, Alicia; Koniak-Griffin, Deborah; Tseng, Chi-hong; Lewis, Mary-Ann; Lamb, Kerry; Lehrer, Danise

    2014-01-01

    The authors studied a health promotion program called PM-Prep (Peer-Mentored Prep), which was designed to improve disaster preparedness among adults living independently in the community. PM-Prep consists of four 2-hour classes co-taught by a health educator and peer-mentors. Adults were randomly assigned to an experimental arm or a wait-list…

  1. Peer-Mentored Preparedness (PM-Prep): A New Disaster Preparedness Program for Adults Living Independently in the Community

    ERIC Educational Resources Information Center

    Eisenman, David Paul; Bazzano, Alicia; Koniak-Griffin, Deborah; Tseng, Chi-hong; Lewis, Mary-Ann; Lamb, Kerry; Lehrer, Danise

    2014-01-01

    The authors studied a health promotion program called PM-Prep (Peer-Mentored Prep), which was designed to improve disaster preparedness among adults living independently in the community. PM-Prep consists of four 2-hour classes co-taught by a health educator and peer-mentors. Adults were randomly assigned to an experimental arm or a wait-list…

  2. Spartanburg Technical College 1998 Work Force Development Survey.

    ERIC Educational Resources Information Center

    Quinley, John W.; Cantrell, Jo Ellen

    The 1998 Work Force Development Study focuses on Spartanburg Technical College's (STC's) (South Carolina) role in preparing new workers and training/retraining the current workforce. Surveys were mailed to employers in business and industry--the response rate was 10%. In addition, a series of focus groups, including various business, industry,…

  3. Reference Collection Development in Academic Libraries: Report of a Survey.

    ERIC Educational Resources Information Center

    Biggs, Mary; Biggs, Victor

    1987-01-01

    A survey of heads of academic library reference services gathered information on reference collection development. Findings included: (1) selection and weeding frequently are not guided by written policies; (2) empirical studies of use are almost nonexistent; and (3) online availability of sources is an important factor in selection. (20…

  4. Development and Validation of the College Drinking Influences Survey

    ERIC Educational Resources Information Center

    Fisher, Celia B.; Fried, Adam L.; Anushko, Andrea

    2007-01-01

    Objective: The authors developed and validated measures of college drinking expectations, psychosocial influences, and values. Participants: Freshmen at college entry (N = 320) and the end of freshman year (N = 420) participated. Methods: The College Drinking Influences Survey, administered in paper and Web-based versions, consists of 3 distinct…

  5. Development and Validation of the College Tobacco Survey.

    ERIC Educational Resources Information Center

    Ott, Carol H.; Cashin, Susan E.; Altekruse, Michael

    2005-01-01

    The authors report on the development and assessment of an instrument to measure baseline campus cigarette use and outcomes from prevention programs, including those using a social norms approach combined with environmental policy change. They administered the 37-item College Tobacco Survey (CTS) to a convenience sample of 1,279 college students…

  6. Development and Validation of the Poverty Attributions Survey

    ERIC Educational Resources Information Center

    Bennett, Robert M.; Raiz, Lisa; Davis, Tamara S.

    2016-01-01

    This article describes the process of developing and testing the Poverty Attribution Survey (PAS), a measure of poverty attributions. The PAS is theory based and includes original items as well as items from previously tested poverty attribution instruments. The PAS was electronically administered to a sample of state-licensed professional social…

  7. Gender Differences in Faculty Development: A Faculty Needs Survey

    ERIC Educational Resources Information Center

    Seritan, Andreea L.; Iosif, Ana-Maria; Hyvonen, Shelby; Lan, Mei-Fang; Boyum, Kathleen; Hilty, Donald

    2010-01-01

    Objective: The authors investigated professional development needs of faculty in the Department of Psychiatry and Behavioral Sciences at the University of California (UC) Davis, while also exploring any existing differences according to gender and academic rank. Methods: An online survey was sent to 75 faculty members, and 41 responses (17 women,…

  8. Several flow visualization and survey techniques developed recently in HARI

    NASA Astrophysics Data System (ADS)

    Fan, Jiechuan; Zhang, Xiaodi; Helian, Huizheng; Zhao, Dong

    1992-12-01

    This paper depicts three flow visualization and survey techniques developed recently at Harbin Aerodynamics Research Institute (HARI), i.e., color helium bubble flow visualization, combined light-sheet flow visualization, and computerized color graphic flow visualization. The principle, performance, and application of them are given in this paper.

  9. Development and Validation of the Poverty Attributions Survey

    ERIC Educational Resources Information Center

    Bennett, Robert M.; Raiz, Lisa; Davis, Tamara S.

    2016-01-01

    This article describes the process of developing and testing the Poverty Attribution Survey (PAS), a measure of poverty attributions. The PAS is theory based and includes original items as well as items from previously tested poverty attribution instruments. The PAS was electronically administered to a sample of state-licensed professional social…

  10. The Development and Application of Expert Systems: A National Survey.

    ERIC Educational Resources Information Center

    Bossinger, June; Milheim, William D.

    1993-01-01

    Discussion of expert systems focuses on a national survey that gathered information concerning the attention and investment given to expert systems by managers and computer professionals in a variety of fields. Highlights include uses of expert systems, types of computers and software used, and expert systems shells and development costs. (18…

  11. Development and Validation of the "Employer Openness Survey"

    ERIC Educational Resources Information Center

    Gilbride, Dennis; Vandergoot, David; Golden, Kristie; Stensrud, Robert

    2006-01-01

    This study describes the four-phase process used in developing the "Employer Openness Survey" (EOS). The EOS is an 18-item instrument designed to measure the openness of employers to hiring, accommodating, and promoting workers with disabilities. During the first phase, the authors generated potential questions and pilot-tested them with…

  12. Airborne Geophysical Surveys Applied to Hydrocarbon Resource Development Environmental Studies

    NASA Astrophysics Data System (ADS)

    Smith, B. D.; Ball, L. B.; Finn, C.; Kass, A.; Thamke, J.

    2014-12-01

    Application of airborne geophysical surveys ranges in scale from detailed site scale such as locating abandoned well casing and saline water plumes to landscape scale for mapping hydrogeologic frameworks pertinent to ground water and tectonic settings relevant to studies of induced seismicity. These topics are important in understanding possible effects of hydrocarbon development on the environment. In addition airborne geophysical surveys can be used in establishing baseline "snapshots", to provide information in beneficial uses of produced waters, and in mapping ground water resources for use in well development. The U.S. Geological Survey (USGS) has conducted airborne geophysical surveys over more than 20 years for applications in energy resource environmental studies. A majority of these surveys are airborne electromagnetic (AEM) surveys to map subsurface electrical conductivity related to plumes of saline waters and more recently to map hydrogeologic frameworks for ground water and plume migration. AEM surveys have been used in the Powder River Basin of Wyoming to characterize the near surface geologic framework for siting produced water disposal ponds and for beneficial utilization in subsurface drip irrigation. A recent AEM survey at the Fort Peck Reservation, Montana, was used to map both shallow plumes from brine pits and surface infrastructure sources and a deeper concealed saline water plume from a failed injection well. Other reported applications have been to map areas geologically favorable for shallow gas that could influence drilling location and design. Airborne magnetic methods have been used to image the location of undocumented abandoned well casings which can serve as conduits to the near surface for coproduced waters. They have also been used in conjunction with geologic framework studies to understand the possible relationships between tectonic features and induced earthquakes in the Raton Basin. Airborne gravity as well as developing deeper

  13. Assessing Consumer Responses to PREPs: A Review of Tobacco Industry and Independent Research Methods

    PubMed Central

    Rees, Vaughan W.; Kreslake, Jennifer M.; Cummings, K. Michael; O'Connor, Richard J.; Hatsukami, Dorothy K.; Parascandola, Mark; Shields, Peter G.; Connolly, Gregory N.

    2009-01-01

    Objective Internal tobacco industry documents and the mainstream literature are reviewed to identify methods and measures for evaluating tobacco consumer response. The review aims to outline areas in which established methods exist, identify gaps in current methods for assessing CR, and consider how these methods might be applied to evaluate PREPs and new products. Methods Internal industry research reviewed included published papers, manuscript drafts, presentations, protocols, and instruments relating to consumer response measures were identified and analyzed. Peer-reviewed research was identified using PubMed and Scopus. Results Industry research on consumer response focuses on product development and marketing. To develop and refine new products, the tobacco industry has developed notable strategies for assessing consumers' sensory and subjective responses to product design characteristics. Independent research is often conducted to gauge the likelihood of future product adoption by measuring consumers' risk perceptions, responses to product, and product acceptability. Conclusions A model which conceptualizes consumer response as comprising the separate, but interacting domains of product perceptions and response to product is outlined. Industry and independent research supports the dual domain model, and provides a wide range of methods for assessment of the construct components of consumer response. Further research is needed to validate consumer response constructs, determine the relationship between consumer response and tobacco user behavior, and improve reliability of consumer response measures. Scientifically rigorous consumer response assessment methods will provide a needed empirical basis for future regulation of PREPs and new products, to counteract tobacco industry influence on consumers, and enhance the public health. PMID:19959675

  14. Concept and development of information flow diagram for literature survey

    SciTech Connect

    Noda, Masaru; Sato, Shoko; Ueda, Tadashi; Tsuchi, Hiroyuki; Koike, Akihisa

    2007-07-01

    The Information Flow Diagram for Literature Survey (IFDLS) has been developed to manage information and procedure in the literature survey phase of the PTAs selection process. It is a tool utilizing information technology, which can organize, analyze, and evaluate information from literature survey and manage their process systematically. IFDLS is able to show the flow of information and data, and the history of information management processing. Information coverage and quality is not homogenous throughout the country and, in some areas, there may not even be sufficient data available to be able to reach a judgment on conformity with the site-specific evaluation factors (SSEF). Literature surveys could only be conducted on a volunteer area before it is nominated as a PIA. However, the absence of information on any factor mentioned will not constitute disqualification of the area. On the contrary, an attempt to compare these sites with analogous areas in Japan will be done to assemble sufficient data and consequently make a decision on whether to proceed further. The application of IFDLS to literature survey phase of the PIA selection process is being proposed. The concept, construction, application and evolution of IFDLS towards application phase on a trial basis are discussed. (authors)

  15. Assessing physics learning identity: Survey development and validation

    NASA Astrophysics Data System (ADS)

    Li, Sissi L.; Demaree, Dedra

    2012-02-01

    Innovative curricula aim to improve content knowledge and the goal of helping students develop practices and skills of authentic scientist through active engagement learning. To students, these classroom practices often seem very different from their previous learning experiences in terms of behavioral expectations, learning attitude, and what learning means. We propose that productive participation in these learning environments require students to modify their identity as learners in addition to refining their science conceptual understanding. In order to measure changes in learning identity, we developed a 49-item survey to assess students' 1) expectations of student and teacher roles, 2) self efficacy towards skills supported in the Investigative Science Learning Environment (ISLE) and 3) attitudes towards social learning. Using principle components exploratory factor analysis, we have established two reliable factors with subscales that measure these student characteristics. This paper presents the survey development, validation and pilot study results.

  16. Lecture to inquiry: The transformation of a tech prep biology teacher

    NASA Astrophysics Data System (ADS)

    Haskell, Deborah Harris

    As teachers implement the National Science Education Standards (NRC, 1996) many have to reform the instructional methods they have used throughout their careers. This case study examines the transformation of Laurie, a 20-year teacher, during her first year of change from a "traditional" textbook/lecture style of teaching to a facilitator of an inquiry-based classroom. Implementing change requires not only pedagogical expertise, but also the belief that the modifications can be made and that the outcomes are significant. Using Bandura's social cognitive theory as a framework, changes in Laurie's self-efficacy, outcome expectancy, and motivation are followed throughout the transition. During her first year of change, Laurie used worksheets, small group activities, and guided inquiry activities, all strategies in which she had high self-efficacy and experienced positive student outcomes. She rarely used class forums, authentic assessment, and formative assessment. Factors that influenced her change were experiential professional development opportunities that allowed her to practice inquiry-based techniques, a change in her teaching environment from college prep chemistry to tech prep biology, autonomy regarding classroom decisions, and reflective decision making as she learned through experience. Using a standards-based biology textbook increased her self-efficacy toward using inquiry-based practices. The textbook format of embedding text in activities rather than adding activities to the text resulted in an increase of the number and frequency of activities done. Facilitating the textbook's Guided Inquiries and Extended Inquiries helped Laurie gain experience with inquiry-based methods. She also realized that when building from the students' concrete experiences, her students were able to attain higher-level thinking skills. The study revealed six factors contributing to Laurie's change process: (a) experiential professional development, (b) motivation for change

  17. Development of a survey to identify vaccine-hesitant parents: the parent attitudes about childhood vaccines survey.

    PubMed

    Opel, Douglas J; Mangione-Smith, Rita; Taylor, James A; Korfiatis, Carolyn; Wiese, Cheryl; Catz, Sheryl; Martin, Diane P

    2011-04-01

    To develop a survey to accurately assess parental vaccine hesitancy. The initial survey contained 17 items in four content domains: (1) immunization behavior; (2) beliefs about vaccine safety and efficacy; (3) attitudes about vaccine mandates and exemptions; and (4) trust. Focus group data yielded an additional 10 survey items. Expert review of the survey resulted in the deletion of nine of 27 items and revisions to 11 of the remaining 18 survey items. Parent pretesting resulted in the deletion of one item, the addition of one item, the revision of four items, and formatting changes to enhance usability. The final survey contains 18 items in the original four content domains. An iterative process was used to develop the survey. First, we reviewed previous studies and surveys on parental health beliefs regarding vaccination to develop content domains and draft initial survey items. Focus groups of parents and pediatricians generated additional themes and survey items. Six immunization experts reviewed the items in the resulting draft survey and ranked them on a 1-5 scale for significance in identifying vaccine-hesitant parents (5 indicative of a highly significant item). The lowest third of ranked items were dropped. The revised survey was pretested with 25 parents to assess face validity, usability and item understandability. The Parent Attitudes about Childhood Vaccines survey was constructed using qualitative methodology to identify vaccine-hesitant parents and has content and face validity. Further psychometric testing is needed.

  18. PrEP as peri-conception HIV prevention for women and men

    PubMed Central

    Heffron, Renee; Pintye, Jillian; Matthews, Lynn T.; Weber, Shannon; Mugo, Nelly

    2016-01-01

    Daily oral tenofovir (TDF)-based pre-exposure prophylaxis (PrEP) is an effective HIV prevention strategy and recommended for men and women with substantial risk of HIV acquisition. The peri-conception period, the stage prior to pregnancy when condom use is necessarily reduced, has elevated HIV risk that can be mitigated by PrEP use. Data from a randomized trial suggest that peri-conception PrEP use by HIV-seronegative women does not increase the risk of pregnancy loss, birth defects or congenital anomalies, preterm birth, or infant growth faltering. Women considering PrEP use throughout pregnancy must weigh the known increased risk of HIV acquisition with unknown risks of drug effects on infant growth. PrEP has been used safely by HIV-seronegative men with HIV-seropositive female partners who have become pregnant. As an effective user-controlled HIV prevention strategy, PrEP offers autonomy and empowerment for HIV prevention and can be recommended alongside antiretroviral therapy, fertility screening, vaginal self-insemination, intercourse timed to peak fertility, medically assisted reproduction, and other safer conception strategies to provide multiple options. The integration of PrEP into safer conception programs is warranted and will safely reduce HIV transmission to women, men and children during the peri-conception period. PMID:26993627

  19. Nutrition environment measures survey-vending: development, dissemination, and reliability.

    PubMed

    Voss, Carol; Klein, Susan; Glanz, Karen; Clawson, Margaret

    2012-07-01

    Researchers determined a need to develop an instrument to assess the vending machine environment that was comparably reliable and valid to other Nutrition Environment Measures Survey tools and that would provide consistent and comparable data for businesses, schools, and communities. Tool development, reliability testing, and dissemination of the Nutrition Environment Measures Survey-Vending (NEMS-V) involved a collaboration of students, professionals, and community leaders. Interrater reliability testing showed high levels of agreement among trained raters on the products and evaluations of products. NEMS-V can benefit public health partners implementing policy and environmental change initiatives as a part of their community wellness activities. The vending machine project will support a policy calling for state facilities to provide a minimum of 30% of foods and beverages in vending machines as healthy options, based on NEMS-V criteria, which will be used as a model for other businesses.

  20. An International Career Development Survey of Critical Care Practitioners

    PubMed Central

    Patel, Mayur B.; Laudanski, Krzysztof; Pandharipande, Pratik P.

    2014-01-01

    OBJECTIVE To understand the career development needs of an international multidisciplinary group of critical care practitioners in the 21st century. DESIGN A web-accessible survey deployed by the In-Training Section of the Society of Critical Care Medicine (SCCM). SETTING University health sciences center. SUBJECTS Physicians (MD, DO), Advanced Practice Provider (NP, PA), Nurses (RN), Pharmacists, and Student members of the SCCM. INTERVENTIONS The survey covered domains of demographics, opinions about career development, and opinions about the SCCM In-Training Section. MEASUREMENTS AND MAIN RESULTS 1,049 of approximately 16,000 SCCM members responded to the survey (7% response rate). Continuing education (280, 26.7%), leadership skills (197, 18.8%), and scientific development (192, 18.3%) are among the most important issues for the respondents. Many critical care practitioners would like to assist SCCM's efforts in career development (948, 90.4%) and many would consider some aspect of committee involvement (796, 75.9%). The SCCM In-Training Section, whose primary mission is career development across the spectrum of providers and expertise levels, needs improved advertisement (981, 93.7%). There is strong support for upcoming Annual Congresses dedicated to career development (834, 79.5%). Of the three main methods of information dissemination for SCCM career development initiatives from the In-Training Section, respondents rank email highest (762, 72.6%), followed by webpages (228, 21.7%) and I-rooms (59, 5.6%). Over half of the SCCM membership surveyed lack a career development mentor in critical care. CONCLUSIONS This is the largest assessment of the international critical care community regarding the career development needs of 21st century critical care practitioner, although the limited response rate makes this work prone to sampling bias. Career development issues are broad and in need of further development by the SCCM In-Training Section. Although these

  1. Development of the Perceived Nutrition Environment Measures Survey.

    PubMed

    Green, Sarah H; Glanz, Karen

    2015-07-01

    Objective, observational measures of nutrition environments are now well established and widely used. Individuals' perceptions of their nutrition environments may be equally or more important, but are less well conceptualized, and comprehensive measures are not available. This paper describes the development of the Perceived Nutrition Environment Measures Survey (NEMS-P), its test-retest reliability, and its ability to discern differences between lower- and higher-SES neighborhoods. This research involved five steps: (1) development of a conceptual model and inventory of items; (2) expert review; (3) pilot testing and cognitive interviews; (4) revising the survey; and (5) administering the revised survey to participants in neighborhoods of high and low SES on two occasions to evaluate neighborhood differences and test-retest reliability. Data were collected in 2010 and 2011 and analyzed in 2011 and 2012. The final survey has 118 items. Fifty-three core items represent three types of perceived nutrition environments: community nutrition environment, consumer nutrition environment, and home food environment. Test-retest reliability for core constructs of perceived nutrition environments was moderate to good (0.52-0.83) for most measured constructs. Residents of higher-SES neighborhoods reported higher availability scores in stores, stronger agreement that healthy options were available in nearby restaurants, and higher scores for accessibility of healthy foods in their homes. The NEMS-P has moderate to good test-retest reliability and can discriminate perceptions of nutrition environments between residents of higher- and lower-SES neighborhoods. This survey is available and ready to be used. Copyright © 2015 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  2. Social, structural, behavioral and clinical factors influencing retention in Pre-Exposure Prophylaxis (PrEP) care in Mississippi

    PubMed Central

    Arnold, Trisha; Brinkley-Rubinstein, Lauren; Chan, Philip A.; Perez-Brumer, Amaya; Bologna, Estefany S.; Beauchamps, Laura; Johnson, Kendra; Mena, Leandro; Nunn, Amy

    2017-01-01

    Pre-exposure prophylaxis (PrEP) is a biomedical intervention that can reduce rates of HIV transmission when taken once daily by HIV-negative individuals. Little is understood about PrEP uptake and retention in care among the populations most heavily impacted by the HIV epidemic, particularly among young men who have sex with men (YMSM) in the Deep South. Therefore, this study explored the structural, social, behavioral, and clinical factors that affect PrEP use and retention in care among YMSM in Jackson, Mississippi. Thirty MSM who were prescribed PrEP at an outpatient primary care clinic were interviewed and included 23 men who had been retained in PrEP care and seven who had not been retained. The mean age of participants was 26.6 years. Most (23) participants were African American. Major factors affecting PrEP use and retention in PrEP care included 1) structural factors such as cost and access to financial assistance for medications and clinical services; 2) social factors such as stigma and relationship status; 3) behavioral factors including sexual risk behaviors; and 4) clinical factors such as perceived and actual side effects. Many participants also discussed the positive spillover effects of PrEP use and reported that PrEP had a positive impact on their health. Four of the seven individuals who had not been retained re-enrolled in PrEP care after completing their interviews, suggesting that case management and ongoing outreach can enhance retention in PrEP care. Interventions to enhance retention in PrEP care among MSM in the Deep South will be most effective if they address the complex structural, social, clinical, and behavioral factors that influence PrEP uptake and retention in PrEP care. PMID:28222118

  3. OligoPrep PVA support for oligonucleotide synthesis in columns on a scale up to 10 micromol.

    PubMed

    Aitken, Sheena; Anderson, Emma

    2007-01-01

    OligoPrep is a macroporous polyvinylacetate (PVA) biodegradable support that has been designed for cost-effective automated synthesis of oligonucleotides using standard phosphoramidite chemistry. Originally developed for large-scale oligonucleotide synthesis in beds and reactors, we present here its utility for medium-scale work of 1-10 micromol in column syntheses on standard DNA synthesizers. We show how an increase in scale, and, therefore, yield, can be achieved without significant increase in reagent quantity. Additional deblock and oxidation cycles can provide high coupling yields, and the use of concentrated ammonia in aqueous methylamine (AMA) for oligonucleotide cleavage and deprotection results in excellent recovery.

  4. The Trauma Center Organizational Culture Survey: development and conduction.

    PubMed

    Davis, Matthew L; Wehbe-Janek, Hania; Subacius, Haris; Pinto, Ruxandra; Nathens, Avery B

    2015-01-01

    The Trauma Center Organizational Culture Survey (TRACCS) instrument was developed to assess organizational culture of trauma centers enrolled in the American College of Surgeons Trauma Quality Program (ACS TQIP). The objective is to provide evidence on the psychometric properties of the factors of TRACCS and describe the current organizational culture of TQIP-enrolled trauma centers. A cross-sectional study was conducted by surveying a sampling of employees at 174 TQIP-enrolled trauma centers. Data collection was preceded by multistep survey development. Psychometric properties were assessed by an exploratory factor analysis (construct validity) and the item-total correlations and Cronbach alpha were calculated (internal reliability). Statistical outcomes of the survey responses were measured by descriptive statistics and mixed effect models. The response rate for trauma center participation in the study was 78.7% (n = 137). The factor analysis resulted in 16 items clustered into three factors as described: opportunity, pride, and diversity, trauma center leadership, and employee respect and recognition. TRACCS was found to be highly reliable with a Cronbach alpha of 0.90 in addition to the three factors (0.91, 0.90, and 0.85). Considerable variability of TRACCS overall and factor score among hospitals was measured, with the largest interhospital deviations among trauma center leadership. More than 80% of the variability in the responses occurred within rather than between hospitals. TRACCS was developed as a reliable tool for measuring trauma center organizational culture. Relationships between TQIP outcomes and measured organizational culture are under investigation. Trauma centers could apply TRACCS to better understand current organizational culture and how change tools can impact culture and subsequent patient and process outcomes. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. SKILL PREP Program for American Indian Students. Final report, 1994

    SciTech Connect

    McCulloh, S.; Huebner, P.

    1995-10-01

    The Scientific Knowledge for Indian Learning and Leadership (SKILL) precollege college program of the South Dakota School of Mines and Technology concluded the 1994 PREP program on July 22, 1994. The program graduated 22 students from the 4-week residential math/science program for American Indian students. Primary academic focus was physics (30 hours); each student was given a bicycle to solve problems on angular momentum and mechanical advantage. Mathematical calculations and problem solving exercises were done in mathematics class (20 hours). Preliminary results in math, physics, and geology show dramatic increases in student achievement over the 4- week period. The program paired every two students with a faculty member or research scientist, and each team completed a research project.

  6. PREP inside and out: marriage education for inmates.

    PubMed

    Einhorn, Lindsey; Williams, Tamara; Stanley, Scott; Wunderlin, Nicole; Markman, Howard; Eason, Joanne

    2008-09-01

    Although research has demonstrated that marriage education has positive effects on relationship quality, little is known about how such services impact relationships where one partner is incarcerated. The current study implemented an adapted version of the Prevention and Relationship Enhancement Program (PREP Inside and Out) for inmates in Oklahoma correctional facilities. Inmates, with or without their partners, participated in the 12-hour program. The impact of the program was investigated on a range of relationship variables including satisfaction with relationship, dedication, confidence, communication skills, friendship, and negative interactions as reported by the inmate partner. Participants reported substantial gains in all variables and in overall satisfaction with their relationship after completing the program, regardless of their gender and racial/ethnic background. Implications for future marriage education programs and research in prisons are discussed.

  7. Technology, design and dementia: an exploratory survey of developers.

    PubMed

    Jiancaro, Tizneem; Jaglal, Susan B; Mihailidis, Alex

    2017-08-01

    Despite worldwide surges in dementia, we still know relatively little about the design of home technologies that support this population. The purpose of this study was to investigate design considerations from the perspective of developers. Participants, including technical and clinical specialists, were recruited internationally and answered web-based survey questions comprising Likert-type responses with text entry options. Developers were queried on 23 technology acceptance characteristics and 24 design practices. In all, forty developers completed the survey. Concerning "technology acceptance", cost, learnability, self-confidence (during use) and usability were deemed very important. Concerning "design practice", developers overwhelmingly valued user-centred design (UCD). In terms of general assistive technology (AT) models, these were largely unknown by technical specialists compared to clinical specialists. Recommendations based on this study include incorporating "self-confidence" into design protocols; examining the implications of "usability" and UCD in this context; and considering empathy-based design approaches to suit a diverse user population. Moreover, clinical specialists have much to offer development teams, particularly concerning the use of conceptual AT models. Implications of rehabilitation Stipulate precise usability criteria. Consider "learnability" and "self-confidence" as technology adoption criteria. Recognize the important theoretical role that clinical specialists can fulfil concerning the use of design schemas. Acknowledge the diversity amongst users with dementia, potentially adopting techniques, such as designing for "extraordinary users".

  8. Development of a Web-Based Survey for Monitoring Daily Health and its Application in an Epidemiological Survey

    PubMed Central

    Ohkusa, Yasushi; Akahane, Manabu; Sano, Tomomi; Okabe, Nobuhiko; Imamura, Tomoaki

    2011-01-01

    Background Early detection of symptoms arising from exposure to pathogens, harmful substances, or environmental changes is required for timely intervention. The administration of Web-based questionnaires is a potential method for collecting information from a sample population. Objective The objective of our study was to develop a Web-based daily questionnaire for health (WDQH) for symptomatic surveillance. Methods We adopted two different survey methods to develop the WDQH: an Internet panel survey, which included participants already registered with an Internet survey company, and the Tokyo Consumers’ Co-operative Union (TCCU) Internet survey, in cooperation with the Japanese Consumers’ Co-operative Union, which recruited participants by website advertising. The Internet panel survey participants were given a fee every day for providing answers, and the survey was repeated twice with modified surveys and collection methods: Internet Panel Survey I was conducted every day, and Internet Panel Survey II was conducted every 3 days to reduce costs. We examined whether the survey remained valid by reporting health conditions on day 1 over a 3-day period, and whether the response rate would vary among groups with different incentives. In the TCCU survey, participants were given a fee only for initially registering, and health information was provided in return for survey completion. The WDQH included the demographic details of participants and prompted them to answer questions about the presence of various symptoms by email. Health information collected by the WDQH was then used for the syndromic surveillance of infection. Results Response rates averaged 47.3% for Internet Panel Survey I, 42.7% for Internet Panel Survey II, and 40.1% for the TCCU survey. During a seasonal influenza epidemic, the WDQH detected a rapid increase in the number of participants with fever through the early aberration reporting system. Conclusions We developed a health observation method

  9. Measuring vaccine hesitancy: The development of a survey tool.

    PubMed

    Larson, Heidi J; Jarrett, Caitlin; Schulz, William S; Chaudhuri, Mohuya; Zhou, Yuqing; Dube, Eve; Schuster, Melanie; MacDonald, Noni E; Wilson, Rose

    2015-08-14

    In March 2012, the SAGE Working Group on Vaccine Hesitancy was convened to define the term "vaccine hesitancy", as well as to map the determinants of vaccine hesitancy and develop tools to measure and address the nature and scale of hesitancy in settings where it is becoming more evident. The definition of vaccine hesitancy and a matrix of determinants guided the development of a survey tool to assess the nature and scale of hesitancy issues. Additionally, vaccine hesitancy questions were piloted in the annual WHO-UNICEF joint reporting form, completed by National Immunization Managers globally. The objective of characterizing the nature and scale of vaccine hesitancy issues is to better inform the development of appropriate strategies and policies to address the concerns expressed, and to sustain confidence in vaccination. The Working Group developed a matrix of the determinants of vaccine hesitancy informed by a systematic review of peer reviewed and grey literature, and by the expertise of the working group. The matrix mapped the key factors influencing the decision to accept, delay or reject some or all vaccines under three categories: contextual, individual and group, and vaccine-specific. These categories framed the menu of survey questions presented in this paper to help diagnose and address vaccine hesitancy.

  10. Pre-exposure Prophylaxis (PrEP) for HIV Infection: How Antiretroviral Pharmacology helps to Monitor and Improve Adherence

    PubMed Central

    Blumenthal, Jill; Haubrich, Richard

    2014-01-01

    Pre-exposure prophylaxis (PrEP) with antiretroviral drugs is a novel biomedical intervention that can prevent HIV transmission among high-risk populations. As findings from multiple PrEP studies have suggested that adherence is vital to achieve the full prevention benefits of PrEP, it is important to understand the clinical pharmacology and pharmacokinetic (PK) properties of PrEP antiretrovirals, the association of PK and PrEP efficacy and the potential for drug concentration measurement to be used as a tool to monitor PrEP adherence. In this review, we examine studies related to PrEP adherence with attention to the clinical pharmacology and pharmacokinetics of current and novel PrEP agents. Studies of animal models, pharmacokinetics and clinical trials related to PrEP and adherence were reviewed. In summary, when combined as part of a comprehensive prevention strategy that includes use of condoms and risk reduction counseling, PrEP has tremendous promise as a adjunctive biomedical HIV prevention intervention, providing that adherence is maintained. PMID:23800167

  11. Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism.

    PubMed

    Oriente, Francesco; Fernandez Diaz, Luis Cesar; Miele, Claudia; Iovino, Salvatore; Mori, Silvia; Diaz, Victor Manuel; Troncone, Giancarlo; Cassese, Angela; Formisano, Pietro; Blasi, Francesco; Beguinot, Francesco

    2008-09-01

    We have examined glucose homeostasis in mice hypomorphic for the homeotic transcription factor gene Prep1. Prep1-hypomorphic (Prep1(i/i)) mice exhibit an absolute reduction in circulating insulin levels but normal glucose tolerance. In addition, these mice exhibit protection from streptozotocin-induced diabetes and enhanced insulin sensitivity with improved glucose uptake and insulin-dependent glucose disposal by skeletal muscle. This muscle phenotype does not depend on reduced expression of the known Prep1 transcription partner, Pbx1. Instead, in Prep1(i/i) muscle, we find normal Pbx1 but reduced levels of the recently identified novel Prep1 interactor p160. Consistent with this reduction, we find a muscle-selective increase in mRNA and protein levels of PGC-1alpha, accompanied by enhanced expression of the GLUT4 transporter, responsible for insulin-stimulated glucose uptake in muscle. Indeed, using L6 skeletal muscle cells, we induced the opposite effects by overexpressing Prep1 or p160, but not Pbx1. In vivo skeletal muscle delivery of p160 cDNA in Prep1(i/i) mice also reverses the molecular phenotype. Finally, we show that Prep1 controls the stability of the p160 protein. We conclude that Prep1 controls insulin sensitivity through the p160-GLUT4 pathway.

  12. Efficient endotoxin removal with a new sanitizable affinity column: Affi-Prep Polymyxin.

    PubMed

    Talmadge, K W; Siebert, C J

    1989-08-04

    A new affinity column packing for removal of endotoxins has been prepared by coupling USP drug-quality polymyxin B to Affi-Prep, a novel synthetic macroporous polymer. Affi-Prep Polymyxin binds endotoxins from a number of different strains of gram-negative bacteria. Endotoxin binding is not significantly affected by 10 mg/ml of bovine serum albumin or human immunoglobulin G, by 1 mg/ml sodium dodecyl sulphate, or by 1 mg/ml deoxycholate. Affi-Prep Polymyxin is stable to treatment with 1.0 M sodium hydroxide, an important property for sanitizing the resin. The resin shows a high ligand stability, since no leakage of polymyxin B from the packing could be detected. Affi-Prep Polymyxin exhibited the highest endotoxin binding efficiency when compared with several commercial agarose affinity packings.

  13. 77 FR 8272 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, PrepCAST.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ... SECURITY Federal Emergency Management Agency Agency Information Collection Activities: Submission for OMB Review; Comment Request, PrepCAST. AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: The Federal Emergency Management Agency (FEMA) will submit the information collection abstracted...

  14. Science, technology, power and sex: PrEP and HIV-positive gay men in Paris.

    PubMed

    Brisson, Julien; Nguyen, Vinh-Kim

    2017-10-01

    The pre-exposure prophylaxis (PrEP) drug Truvada is a new HIV prevention technology that is predominantly promoted as relevant to HIV-negative gay men. This paper explores what PrEP represents for HIV-positive gay men living in Paris, based upon data collected through interviews and ethnographic research. While HIV-positive gay men do not directly consume Truvada through PrEP, they nonetheless hold opinions and understandings of this drug, specifically as it relates to their own sexuality. This paper expands the representations and meanings of this new technology in a different light through the voices of gay men living with HIV in Paris. The main argument of this article is that PrEP as an additional HIV prevention tool blurs the lines between science, technologies and human sexuality.

  15. Purification and Characterization of a DNA-Binding Recombinant PREP1:PBX1 Complex

    PubMed Central

    Mathiasen, Lisa; Bruckmann, Chiara; Pasqualato, Sebastiano; Blasi, Francesco

    2015-01-01

    Human PREP1 and PBX1 are homeodomain transcriptional factors, whose biochemical and structural characterization has not yet been fully described. Expression of full-length recombinant PREP1 (47.6 kDa) and PBX1 (46.6 kDa) in E. coli is difficult because of poor yield, high instability and insufficient purity, in particular for structural studies. We cloned the cDNA of both proteins into a dicistronic vector containing an N-terminal glutathione S-transferase (GST) tag and co-expressed and co-purified a stable PBX1:PREP1 complex. For structural studies, we produced two C-terminally truncated complexes that retain their ability to bind DNA and are more stable than the full-length proteins through various purification steps. Here we report the production of large amounts of soluble and pure recombinant human PBX1:PREP1 complex in an active form capable of binding DNA. PMID:25856340

  16. 77 FR 10542 - Revision of the National Preparedness for Response Exercise Program (PREP) Guidelines

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ... Guidelines to reflect changes to regulations, agency reorganizations, and lessons learned from past... reflect agency reorganizations, preparedness and response lessons learned, and new regulations, including... SECURITY Coast Guard Revision of the National Preparedness for Response Exercise Program (PREP) Guidelines...

  17. Preliminary investigation of the advertising and availability of PREPs, the new "safe" tobacco products.

    PubMed

    Hickman, Norval; Klonoff, Elizabeth A; Landrine, Hope; Kashima, Kennon; Parekh, Bina; Fernandez, Senaida; Thomas, Kamala; Brouillard, Catherine; Zolezzi, Michele; Jensen, Jennifer; Weslowski, Zorahna

    2004-08-01

    The tobacco industry recently introduced a new set of "safe" cigarettes and nicotine delivery devices that purportedly entail reduced tobacco-related disease risk due to their lower level of some carcinogens and toxins. Little is know about the biological impact of these potential reduced exposure products (PREPs) and nothing is known about their advertising and availability. Hence, two pilot studies were conducted to examine the latter issues for the first time. In Study 1, we examined tobacco ads in 10 popular magazines 1998--2002 and found that only 1% of ads were for PREPs. In Study 2, we attempted to purchase PREPs in a random sample of 113 small stores and found that only 4.4% sold any PREP. These preliminary findings tentatively suggest that the industry might not yet be heavily invested in products that have the potential to increase tobacco use by decreasing its perceived harm. Studies with larger samples are recommended.

  18. Purification and characterization of a DNA-binding recombinant PREP1:PBX1 complex.

    PubMed

    Mathiasen, Lisa; Bruckmann, Chiara; Pasqualato, Sebastiano; Blasi, Francesco

    2015-01-01

    Human PREP1 and PBX1 are homeodomain transcriptional factors, whose biochemical and structural characterization has not yet been fully described. Expression of full-length recombinant PREP1 (47.6 kDa) and PBX1 (46.6 kDa) in E. coli is difficult because of poor yield, high instability and insufficient purity, in particular for structural studies. We cloned the cDNA of both proteins into a dicistronic vector containing an N-terminal glutathione S-transferase (GST) tag and co-expressed and co-purified a stable PBX1:PREP1 complex. For structural studies, we produced two C-terminally truncated complexes that retain their ability to bind DNA and are more stable than the full-length proteins through various purification steps. Here we report the production of large amounts of soluble and pure recombinant human PBX1:PREP1 complex in an active form capable of binding DNA.

  19. The TALE class homeobox gene Smed-prep defines the anterior compartment for head regeneration.

    PubMed

    Felix, Daniel A; Aboobaker, A Aziz

    2010-04-22

    Planaria continue to blossom as a model system for understanding all aspects of regeneration. They provide an opportunity to understand how the replacement of missing tissues from preexisting adult tissue is orchestrated at the molecular level. When amputated along any plane, planaria are capable of regenerating all missing tissue and rescaling all structures to the new size of the animal. Recently, rapid progress has been made in understanding the developmental pathways that control planarian regeneration. In particular Wnt/beta-catenin signaling is central in promoting posterior fates and inhibiting anterior identity. Currently the mechanisms that actively promote anterior identity remain unknown. Here, Smed-prep, encoding a TALE class homeodomain, is described as the first gene necessary for correct anterior fate and patterning during planarian regeneration. Smed-prep is expressed at high levels in the anterior portion of whole animals, and Smed-prep(RNAi) leads to loss of the whole brain during anterior regeneration, but not during lateral regeneration or homeostasis in intact worms. Expression of markers of different anterior fated cells are greatly reduced or lost in Smed-prep(RNAi) animals. We find that the ectopic anterior structures induced by abrogation of Wnt signaling also require Smed-prep to form. We use double knockdown experiments with the S. mediterranea ortholog of nou-darake (that when knocked down induces ectopic brain formation) to show that Smed-prep defines an anterior fated compartment within which stem cells are permitted to assume brain fate, but is not required directly for this differentiation process. Smed-prep is the first gene clearly implicated as being necessary for promoting anterior fate and the first homeobox gene implicated in establishing positional identity during regeneration. Together our results suggest that Smed-prep is required in stem cell progeny as they form the anterior regenerative blastema and is required for

  20. The TALE Class Homeobox Gene Smed-prep Defines the Anterior Compartment for Head Regeneration

    PubMed Central

    Felix, Daniel A.; Aboobaker, A. Aziz

    2010-01-01

    Planaria continue to blossom as a model system for understanding all aspects of regeneration. They provide an opportunity to understand how the replacement of missing tissues from preexisting adult tissue is orchestrated at the molecular level. When amputated along any plane, planaria are capable of regenerating all missing tissue and rescaling all structures to the new size of the animal. Recently, rapid progress has been made in understanding the developmental pathways that control planarian regeneration. In particular Wnt/beta-catenin signaling is central in promoting posterior fates and inhibiting anterior identity. Currently the mechanisms that actively promote anterior identity remain unknown. Here, Smed-prep, encoding a TALE class homeodomain, is described as the first gene necessary for correct anterior fate and patterning during planarian regeneration. Smed-prep is expressed at high levels in the anterior portion of whole animals, and Smed-prep(RNAi) leads to loss of the whole brain during anterior regeneration, but not during lateral regeneration or homeostasis in intact worms. Expression of markers of different anterior fated cells are greatly reduced or lost in Smed-prep(RNAi) animals. We find that the ectopic anterior structures induced by abrogation of Wnt signaling also require Smed-prep to form. We use double knockdown experiments with the S. mediterranea ortholog of nou-darake (that when knocked down induces ectopic brain formation) to show that Smed-prep defines an anterior fated compartment within which stem cells are permitted to assume brain fate, but is not required directly for this differentiation process. Smed-prep is the first gene clearly implicated as being necessary for promoting anterior fate and the first homeobox gene implicated in establishing positional identity during regeneration. Together our results suggest that Smed-prep is required in stem cell progeny as they form the anterior regenerative blastema and is required for

  1. elPrep: High-Performance Preparation of Sequence Alignment/Map Files for Variant Calling

    PubMed Central

    Decap, Dries; Fostier, Jan; Reumers, Joke

    2015-01-01

    elPrep is a high-performance tool for preparing sequence alignment/map files for variant calling in sequencing pipelines. It can be used as a replacement for SAMtools and Picard for preparation steps such as filtering, sorting, marking duplicates, reordering contigs, and so on, while producing identical results. What sets elPrep apart is its software architecture that allows executing preparation pipelines by making only a single pass through the data, no matter how many preparation steps are used in the pipeline. elPrep is designed as a multithreaded application that runs entirely in memory, avoids repeated file I/O, and merges the computation of several preparation steps to significantly speed up the execution time. For example, for a preparation pipeline of five steps on a whole-exome BAM file (NA12878), we reduce the execution time from about 1:40 hours, when using a combination of SAMtools and Picard, to about 15 minutes when using elPrep, while utilising the same server resources, here 48 threads and 23GB of RAM. For the same pipeline on whole-genome data (NA12878), elPrep reduces the runtime from 24 hours to less than 5 hours. As a typical clinical study may contain sequencing data for hundreds of patients, elPrep can remove several hundreds of hours of computing time, and thus substantially reduce analysis time and cost. PMID:26182406

  2. Brief Report: PrEP Uptake, Adherence, and Discontinuation Among California YMSM Using Geosocial Networking Applications.

    PubMed

    Holloway, Ian W; Dougherty, Ryan; Gildner, Jennifer; Beougher, Sean C; Pulsipher, Craig; Montoya, Jorge A; Plant, Aaron; Leibowitz, Arleen

    2017-01-01

    We investigated pre-exposure prophylaxis (PrEP) uptake, adherence, and discontinuation among young app-using men who have sex with men in California (N = 761). Approximately, 9.7% of participants had ever used PrEP; 87% of those deemed good candidates for screening (indicated by a Centers for Disease Control and Prevention risk index score ≥10) were not current or past users. PrEP use was associated with higher income [adjusted odds ratio (aOR): 4.13; confidence interval (CI): 1.87 to 9.12], receptive condomless anal sex (aOR: 3.41; CI: 1.71 to 6.78), HIV-positive sex partners (aOR: 2.87; CI: 1.53 to 5.38), popper use (aOR: 3.47; CI: 1.96 to 6.13), and recent sexually transmitted infection diagnosis (aOR: 2.90; CI: 1.64 to 5.13). Some users (41.5%) wanted help remembering to take PrEP. The top reason for discontinuation was concern about long-term side effects (33.0%). Young men who have sex with men app users are prime candidates for PrEP, despite low uptake. Apps may be useful tools for PrEP information dissemination, adherence monitoring, and support.

  3. Preferences for HIV pre-exposure prophylaxis (PrEP) information among men-who-have-sex-with-men (MSM) at community outreach settings

    PubMed Central

    Merchant, Roland C.; Corner, David; Garza, Eduardo; Guan, Wentao; Mayer, Kenneth H.; Brown, Larry; Chan, Philip A

    2016-01-01

    Community outreach efforts to increase HIV pre-exposure prophylaxis (PrEP) utilization by at risk men-who-have-sex-with-men (MSM) first need to elucidate preferences for learning about PrEP and linking to PrEP resources. In this pilot study, we observed that among MSM recruited through community outreach, HIV sexual risk-taking was significant, yet self-perceived PrEP knowledge was low and interest in learning more about PrEP was moderate. Most preferred learning about PrEP and being provided local PrEP clinic information through electronic media. However, receipt of PrEP information alone did not appear to motivate these men into presenting to a local clinic for PrEP evaluation. PMID:27076865

  4. Health Education Programs Developed in Suffolk Schools. A Survey of Locally Developed Health Education Materials.

    ERIC Educational Resources Information Center

    Keough, John J.; And Others

    This report is a summary of the results of a questionnaire survey of locally developed health education materials. This guide has been prepared to assist school districts in the planning and initiation or expansion of local health programs. It reports on the current status of locally developed programs in the county. Hopefully, this information…

  5. Development of an Introductory Oceanography Concept Inventory Survey

    NASA Astrophysics Data System (ADS)

    Arthurs, L.; Marchitto, T.

    2008-12-01

    Concept inventories are one type of assessment that can be used to evaluate whether a student has an accurate and working knowledge of a specific set of concepts. Although such assessment tools have been developed in astronomy, biology, chemistry, engineering, fluid mechanics, geology, and physics, none has been available. Our development of an Introductory Oceanography Concept Inventory Survey (IO-CIS) serves to fill this gap. Much of the development of the IO-CIS utilized students enrolled in the Spring 2008 Introduction to Oceanography course taught at the University of Colorado at Boulder. The first step in the development of IO-CIS involved the identification and selection of the critical concepts to be addressed in the course and the survey. Next, learning goals were defined for each critical concept. These learning goals then provided the basis for framing open-ended questions that were administered to students in pre-module in-class Concept Inventory Exercises (CIEs). These open-ended questions each underwent validation and revision with expert and novice input prior to being administered in a CIE. Each CIE comprised 4-5 open-ended questions, which each contained 1-4 parts. During the semester, 4 different CIEs were administered, with the number of respondents for each CIE ranging from 57-134. Student responses were then binned according to misconceptions and alternate conceptions, tallied, and "distractors" were written based on the most popular bins using the same language employed by students in their responses. Student responses were also used as part of the validation process to ensure that the questions were interpreted by students in the manner intended. Student responses were also used as a basis to discard particular questions from inclusion in the overall IO-CIS. After the initial IO-CIS questions and distractors had been designed as described above, 23 one-on-one student interviews were conducted as part of the validation process. As a result of

  6. Barriers and facilitators to pre-exposure prophylaxis (PrEP) eligibility screening and ongoing HIV testing among target populations in Bondo and Rarieda, Kenya: Results of a consultation with community stakeholders

    PubMed Central

    2014-01-01

    Background As pre-exposure prophylaxis (PrEP) moves closer to availability in developing countries, practical considerations for implementation become important. We conducted a consultation with district-level community stakeholders experienced in HIV-prevention interventions with at-risk populations in Bondo and Rarieda, Kenya to generate locally grounded approaches to the future rollout of oral PrEP to four populations: fishermen, widows, female sex workers, and serodiscordant couples. Methods The 20 consultation participants represented the Ministry of Health, faith- and community-based organizations, health facilities, community groups, and nongovernmental organizations. Participants divided into breakout groups and followed a structured discussion guide asking them to identify barriers to implementing HIV-prevention interventions (including PrEP) with each population. Questions also solicited solutions for addressing these barriers, as well as other facilitators for PrEP implementation. In particular, questions focused on how to encourage people to screen for PrEP eligibility by having HIV and other blood tests and how to encourage compliance with ongoing HIV testing. Results The barriers and facilitators/solutions discussants provided were frequently population-specific, but there were also broad-level similarities across populations. Service delivery barriers to HIV-prevention interventions concerned the need for staff trained to address the needs of particular populations. Service delivery facilitators to provision of ongoing HIV testing consisted of offering testing options besides facility-based testing. Stigma was the main community-level barrier for all groups, whereas barriers at the level of target populations included mobility; lifestyle and life circumstances, especially cultural norms among fishermen and widows; and fears, lack of awareness, and misinformation. Proposed facilitators and strategies for addressing community- and population

  7. Language Surveys in Developing Nations. Papers and Reports on Sociolinguistic Surveys.

    ERIC Educational Resources Information Center

    Ohannessian, Sirirpi, Ed.; And Others

    This volume is a selection of papers prepared for a conference on sociolinguistically oriented language surveys organized by the Center for Applied Linguistics and held in New York in September 1971. The purpose of the conference was to review the role and function of such language surveys in the light of surveys conducted in recent years. The…

  8. Survey Instrument Validity Part I: Principles of Survey Instrument Development and Validation in Athletic Training Education Research

    ERIC Educational Resources Information Center

    Burton, Laura J.; Mazerolle, Stephanie M.

    2011-01-01

    Context: Instrument validation is an important facet of survey research methods and athletic trainers must be aware of the important underlying principles. Objective: To discuss the process of survey development and validation, specifically the process of construct validation. Background: Athletic training researchers frequently employ the use of…

  9. Survey of European Programs: Education for Urbanization in the Developing Countries. An International Urbanization Survey Report to the Ford Foundation.

    ERIC Educational Resources Information Center

    Bernstein, Beverly

    This report is intended as a contribution to the International Urbanization Survey, initiated by The Ford Foundation. The Survey is designed to review and assess experience in the complex problems posed by the rapid growth of urban centres throughout the developing countries. The terms of reference used here were broadly taken to be as follows: to…

  10. Raising Awareness of Pre-Exposure Prophylaxis (PrEP) among Women in New York City: Community and Provider Perspectives.

    PubMed

    Collier, Kate L; Colarossi, Lisa G; Sanders, Kim

    2017-03-01

    This study explored the knowledge, attitudes, and perceived facilitators and barriers to adoption of HIV pre-exposure prophylaxis (PrEP) among black women and Latinas in the Bronx, NY. Data were collected in focus group discussions (FGDs) held separately with staff (n = 21) and black and Latina female clients aged 18 to 50 (n = 23) of four organizations providing health and social services. Participants were also asked to give feedback about four action messages regarding PrEP for a social marketing campaign. Transcripts were analyzed by two researchers using grounded theory. We found that the majority of clients (74%) and staff (57%) had not heard about PrEP before participating in the FGDs. Following brief educational messaging about PrEP, participants identified potential facilitators and barriers to PrEP uptake among women, and expressed enthusiasm for more widespread efforts to raise awareness about PrEP as an HIV prevention option. Participants preferred an action message that was brief, referred to PrEP as a pill, and did not mention condoms or STD testing. These findings demonstrate the need to raise awareness about PrEP among women and build the capacity of women-serving organizations to educate, screen, and refer or provide PrEP services.

  11. Benefits of PrEP as an Adjunctive Method of HIV Prevention During Attempted Conception Between HIV-uninfected Women and HIV-infected Male Partners.

    PubMed

    Hoffman, Risa M; Jaycocks, Amber; Vardavas, Raffaele; Wagner, Glenn; Lake, Jordan E; Mindry, Deborah; Currier, Judith S; Landovitz, Raphael J

    2015-11-15

    Data on effectiveness of preexposure prophylaxis (PrEP) for human immunodeficiency virus (HIV)-uninfected women attempting conception with HIV-infected male partners are limited to observational studies. To explore the benefits of PrEP for conception, we developed a model to estimate the average annual probability of a woman remaining HIV-uninfected and having a child ("successful" outcome) via condomless sex with an HIV-infected male. The outcome likelihood is dependent upon parameters defining HIV-1 infectivity. We simulated 2 scenarios: optimal (condomless sex acts limited to the ovulation window), and suboptimal (acts not limited to ovulation). In the optimal scenario when the male is on antiretroviral therapy (ART), the average annual probability of the successful outcome is 29.1%, increasing to 29.2% with the addition of PrEP (P = .45). In the suboptimal scenario, the probability is 26.8% with ART alone versus 27.3% with ART/PrEP (P < .0001). Older maternal age reduces the probability of success in both scenarios, particularly after age 30. In our model, PrEP provides little added benefit when the HIV-infected male partner is on ART, condomless sex is limited to the ovulation window, and other modifiable transmission risks are optimized. Older female age decreases the probability of success by increasing the number of condomless sex acts required for conception. © The Author 2015. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  12. Preliminary Design Development of ITER X-ray Survey Spectrometer

    NASA Astrophysics Data System (ADS)

    Varshney, Sanjeev; Kumar, Siddharth; Mishra, Sapna; Yadav, Namita; Subhush, P. V.; Chaitanya, T. S.; Jha, Shivakant; Kumar, Vinay; Barnsley, Robin; Bernascolle, Philippe; Casal, Natalia; Bertschinger, Gunter; Simrock, Stefan; Drevon, Jean-Marc; Walsh, Michael

    2017-04-01

    The preliminary design of XRCS Survey spectrometer for ITER has been developed addressing many challenges snch as designing a ∼ 8.0 m long, vacuum extending sight-tube that interfaces crystal spectrometer, placed in the port-cell, with equatorial port-plug (EPP-11) while allowing ∼ 50 mm machine movements, and optimizing neutron shield design so that systems can fit into the available space and still the shutdown dose rates (SDDR) remains within the safe limits. The design detailing has been done for the sight-tube and its components addressing the ITER specific requirements. Engineering and neutronic analysis are performed tor estimating the thermal displacement, stresses in the front-end components, neutron flux on the sight-tube components, SDDRs in the interspace region etc.

  13. Development and Validation of the College Drinking Influences Survey

    PubMed Central

    Fisher, Celia B.; Fried, Adam L.; Anushko, Andrea

    2008-01-01

    Objective The authors developed and validated measures of college drinking expectations, psychosocial influences, and values. Participants Freshmen at college entry (N = 320) and the end of freshman year (N = 420) participated. Methods The College Drinking Influences Survey, administered in paper and Web-based versions, consists of 3 distinct scales: (1) the College Drinking Expectations Scale assesses expectations for drinking norms and consequences; (2) the Psychosocial Drinking Inventory evaluates social influences, stress, and sensation seeking; and (3) the Drinking Values Scale assesses drinking decisions based on personal choice, social responsibility, and institutional obligation. Results Factor analysis, interitem reliability, and correlations with existing instruments demonstrated validity and reliability. Differences between the sexes were in predicted directions, and multiple regression using subscale scores as predictors accounted for significant variance in drinking behaviors across the freshman year. Conclusions Data support the usefulness of the scales for identifying student alcohol risk and protective factors. PMID:18089502

  14. Development of a drug and alcohol information survey.

    PubMed

    Gough, H G

    1985-04-01

    Psychological measurement in regard to using drugs, alcohol, or other substances should attend to personological, attitudinal, and informational factors. Standardized tests are available for assessing personological and attitudinal variables, but not for knowledge. To develop a test of information, 45 multiple-choice items were correlated with total and part scores in samples of 132 men and 71 women; 35 items with significant (p less than .05) coefficients and other desirable properties were retained for a Drug and Alcohol Information Survey (DAIS). For 33 male and 36 female college students participating in an intensive psychological assessment program, scores on the DAIS were positively associated with (1) ratings of modernity, sensation seeking, originality, and nonorderliness; (2) personality scales for status propensity, sociability, social presence, and rebelliousness; and (3) a nonverbal test of field-independent cognitive ability. High scorers on the DAIS also reported more frequent use of marijuana, alcohol, and tobacco than did students with low scores.

  15. Comparison of the National Survey of Compensation with other surveys of research and development professionals. Final report on universe update

    SciTech Connect

    Newborg, J.; Spurgeon, M.; Price, B.; Evans, P.

    1981-10-01

    The National Survey of Compensation Paid Scientists and Engineers Engaged in Research and Development (NSC) has been conducted for the Department of Energy since 1967. During this time the NSC has come to be considered the most comprehensive survey of its kind available in the United States. Its methodology and results are reliable and highly useful to compensation personnel in research and development (R and D) establishments. Each year project staff pinpoint areas of improvement which are necessary and desirable. The three tasks that are the subject of this report have been undertaken to maintain and improve the NSC and increase its usefulness to participants. The three tasks are: an update of the universe listing; comparison of NSC survey methodology and results with other surveys of research and development professionals; and development of a methodology to project salaries for the near-term. Each task is described.

  16. Adapting behavioural surveillance to antiretroviral-based HIV prevention: reviewing and anticipating trends in the Australian Gay Community Periodic Surveys.

    PubMed

    Holt, Martin; Lea, Toby; Mao, Limin; Zablotska, Iryna; Lee, Evelyn; de Wit, John B F; Prestage, Garrett

    2016-08-29

    Background: In Australia, the preventative use of antiretroviral drugs [pre-exposure prophylaxis (PrEP) and treatment as prevention] is being embraced to protect individuals at high risk of HIV and reduce onward transmission. Methods: The adaptation of a behavioural surveillance system, the Gay Community Periodic Surveys, was reviewed to monitor the uptake and effect of new prevention strategies in Australia's primary HIV-affected population (gay and bisexual men, GBM). The national trends in key indicators during 2000-15 were reviewed and a new measure to take account of antiretroviral-based prevention was developed. Results: Between 2000 and 2015, there were significant increases (P<0.001) in annual HIV testing (56.1-64.8%), condomless sex with casual partners (26.8-38.8%) and the proportion of HIV-positive men on HIV treatment (72.5-88.4%) and with an undetectable viral load (73.7-94.7%). The proportion of casual partners who were HIV negative, not on PrEP and who engaged in receptive condomless sex also increased between 2000 and 2015 from 12.8 to 19.3%. Two scenarios anticipating the effect of PrEP highlighted the need to target GBM who engage in receptive condomless sex while also sustaining condom use at a population level. Conclusions: Behavioural surveillance can be successfully adapted to follow the effect of antiretroviral-based prevention. It is anticipated that HIV testing and HIV treatment will continue to increase among Australian GBM, but to prevent new infections, intervention in the growing proportion of GBM who have condomless sex with casual partners is needed. For PrEP to have its desired effect, condom use needs to be sustained.

  17. Developing Culturally Responsive Surveys: Lessons in Development, Implementation, and Analysis from Brazil's African Descent Communities

    ERIC Educational Resources Information Center

    Bowen, Merle L.; Tillman, Ayesha S.

    2015-01-01

    Considerable empirical research, along with a growing body of conceptual and theoretical literature, exists on the role of culture and context in evaluation. Less scholarship has examined culturally responsive surveys in the context of international evaluation. In this article, the authors present lessons learned from the development,…

  18. Educational Developers' Experiences of Negative Faculty Attitudes towards Teaching and Development--An International Survey

    ERIC Educational Resources Information Center

    Ekecrantz, Stefan; Schwieler, Elias

    2016-01-01

    In this article, results from an international survey on the experiences of educational developers' experiences of teachers' attitudes, emotions, and normative values in higher education are presented. Teacher-student relationships have a substantial impact on student learning and the general learning climate, but have still received relatively…

  19. Vocabulary Development in European Portuguese: A Replication Study Using the Language Development Survey

    ERIC Educational Resources Information Center

    Rescorla, Leslie; Nyame, Josephine; Dias, Pedro

    2016-01-01

    Purpose: Our objective was to replicate previous cross­linguistic findings by comparing Portuguese and U.S. children with respect to (a) effects of language, gender, and age on vocabulary size; (b) lexical composition; and (c) late talking. Method: We used the Language Development Survey (LDS; Rescorla, 1989) with children (18-35 months) learning…

  20. Vocabulary Development in European Portuguese: A Replication Study Using the Language Development Survey

    ERIC Educational Resources Information Center

    Rescorla, Leslie; Nyame, Josephine; Dias, Pedro

    2016-01-01

    Purpose: Our objective was to replicate previous cross­linguistic findings by comparing Portuguese and U.S. children with respect to (a) effects of language, gender, and age on vocabulary size; (b) lexical composition; and (c) late talking. Method: We used the Language Development Survey (LDS; Rescorla, 1989) with children (18-35 months) learning…

  1. Men who have sex with men starting pre-exposure prophylaxis (PrEP) are at risk of HCV infection: evidence from the Amsterdam PrEP study.

    PubMed

    Hoornenborg, Elske; Achterbergh, Roel C A; Schim Van Der Loeff, Maarten F; Davidovich, Udi; Hogewoning, Arjan; Vries, Henry J C de; Schinkel, Janke; Prins, Maria; Laar, Thijs J W van de

    2017-05-01

    Hepatitis C virus (HCV) has been recognised as an emerging sexually transmitted infection (STI) among HIV-positive men who have sex with men (MSM). However, HIV-negative MSM at high risk for HIV might also be at increased risk for HCV. We studied the HCV prevalence in HIV-negative MSM who start pre-exposure prophylaxis (PrEP) in Amsterdam. Phylogenetic analysis was used to compare HCV strains obtained from HIV-negative and HIV-positive MSM. At enrolment in the Amsterdam PrEP (AMPrEP) demonstration project, HIV-negative MSM were tested for the presence of HCV antibodies and HCV RNA. If positive for HCV RNA, an HCV NS5B gene fragment (709 bp) was sequenced and compared with HCV isolates from HIV-positive MSM (n = 223) and risk groups other than MSM (n = 153), using phylogenetic analysis. Of 375 HIV-negative MSM enrolled in AMPrEP, 18 (4.8%, 95%CI 2.9%-7.5%) of participants were anti-HCV and/or HCV RNA positive at enrolment; 15/18 (83%) had detectable HCV RNA. HCV genotyping showed genotype 1a (73%), 4d (20%) and 2b (7%). All HCV-positive MSM starting PrEP were part of MSM-specific HCV clusters containing MSM with and without HIV. HCV prevalence among HIV-negative MSM who started PrEP was higher than previously reported. All HIV-negative HCV-positive MSM were infected with HCV strains already circulating among HIV-positive MSM. The increasing overlap between sexual networks of HIV-positive and HIV-negative MSM might result in an expanding HCV-epidemic irrespective of HIV-status. Hence, routine HCV testing should be offered to MSM at high risk for HIV, especially for those enrolling in PrEP programs.

  2. Faculty development and medical education units in India: a survey.

    PubMed

    Adkoli, B V; Sood, Rita

    2009-01-01

    Faculty development in medical education is gaining momentum in India. While planning a National Conference on Medical Education (NCME 2007), we did a survey of principals and faculty of medical colleges to understand the status of faculty development programmes and medical education units in medical colleges in India. Questionnaires were sent to principals of medical colleges by surface mail and to faculty through a web-based programme to elicit information on various aspects of faculty development programmes and medical education units. The responses of both groups were analysed. The number of medical education units has increased rapidly after regulations have been revised in 1997 by the Medical Council of India. The main activities of medical education units were to conduct workshops targeted at medical teachers. The frequently covered topics were teaching-learning, media and student assessment. Lectures dominated the methodology of imparting information. Evaluation was done mainly by feedback questionnaires and pre-test/post-test questionnaires. Projects and follow up were rarely used. The responses from both groups were strikingly similar. The major strengths of medical education units were perceived as availability of trained and motivated faculty, good infrastructure and supportive leadership. The shortcomings were lack of infrastructure, funding and full-time faculty, besides time constraints and resistance to change. The respondents suggested strengthening of infrastructure, appointment of full-time faculty and staff, incentives and recognition of contributions to faculty development, making participation a mandatory requirement, extending the scope of faculty development programmes to include research and networking at the national level. Conclusion. The study reveals the need for policy decisions that support functioning of medical education units in India besides active participation of the faculty.

  3. The effect of using RC prep during root canal preparation on the incidence of dentinal defects.

    PubMed

    Adl, Alireza; Sedigh-Shams, Mahdi; Majd, Marjan

    2015-03-01

    The purpose of this in vitro study was to evaluate the effect of using RC Prep (Well-Prep, Vericom Co, Anyang, Korea) during root canal preparation on the incidence of defects in root canal walls. One hundred extracted mandibular incisors with single canals were randomly divided into 1 control group and 4 experimental groups (n = 20). The teeth in group 1 (control) were coronally flared with Gates Glidden drills (Mani, Japan), but no further preparation was made. All teeth in the experimental groups were first coronally flared with Gates Glidden drills and then prepared similarly by means of ProTaper instruments (Dentsply Maillefer, Ballaigues, Switzerland). The difference between the experimental groups was the following: in group 2, saline was used as an irrigation solution without the application of RC Prep; in group 3, teeth were irrigated with saline, and RC Prep was also applied to canals before the insertion of each file; in group 4, sodium hypochlorite (NaOCl) was used for irrigation without the application of RC Prep; and in group 5, both NaOCl and RC Prep were used. The apical root surface and horizontal sections 3, 6, and 9 mm from the apex were observed under a microscope. The presence of cracks was noted. The chi-square test and Fisher exact test were used for statistical analysis of differences between and among the groups. A significant difference was found between and among the 5 groups (P < .05). Group 4 (NaOCl), which had the highest number of cracked teeth, was significantly different from group 1 (control) (P < .05). RC Prep, with both saline and NaOCl, had no significant effect on the incidence of microcrack formation (P > .05). When data were pooled, regardless of whether RC Prep was used, there was a significant difference between saline (groups 2 + 3) and NaOCl (groups 4 + 5) (P < .05). RC Prep was unable to reduce the risk of dentinal defects. NaOCl caused more defects compared with saline. Copyright © 2015. Published by Elsevier Inc.

  4. Willingness to Take PrEP and Potential for Risk Compensation Among Highly Sexually Active Gay and Bisexual Men

    PubMed Central

    Grov, Christian; Whitfield, Thomas H. F.; Rendina, H. Jonathon; Ventuneac, Ana; Parsons, Jeffrey T.

    2015-01-01

    Once-daily Truvada (Emtricitabine/Tenofovir) as a method of pre-exposure prophylaxis (PrEP) is one of the most promising biomedical interventions to eliminate new HIV infections; however, uptake among gay, bisexual, and other men who have sex with men has been slow amidst growing concern in popular/social media that PrEP use will result in reduced condom use (i.e., risk compensation). We investigated demographic, behavioral, and psychosocial differences in willingness to use PrEP as well as the perceived impact of PrEP on participants’ condom use in a sample of 206 highly sexually active HIV-negative gay and bisexual men. Nearly half (46.1 %) said they would be willing to take PrEP if it were provided at no cost. Although men willing to take PrEP (vs. others) reported similar numbers of recent casual male partners (<6 weeks), they had higher odds of recent receptive condomless anal sex (CAS)—i.e., those already at high risk of contracting HIV were more willing to take PrEP. Neither age, race/ethnicity, nor income were associated with willingness to take PrEP, suggesting equal acceptability among subpopulations that are experiencing disparities in HIV incidence. There was limited evidence to suggest men would risk compensate. Only 10 % of men who had not engaged in recent CAS felt that PrEP would result in them starting to have CAS. Men who had not tested for HIV recently were also significantly more likely than others to indicate willingness to take PrEP. Offering PrEP to men who test infrequently may serve to engage them more in routine HIV/STI testing and create a continued dialogue around sexual health between patient and provider in order to prevent HIV infection. PMID:25735243

  5. Willingness to Take PrEP and Potential for Risk Compensation Among Highly Sexually Active Gay and Bisexual Men.

    PubMed

    Grov, Christian; Whitfield, Thomas H F; Rendina, H Jonathon; Ventuneac, Ana; Parsons, Jeffrey T

    2015-12-01

    Once-daily Truvada (Emtricitabine/Tenofovir) as a method of pre-exposure prophylaxis (PrEP) is one of the most promising biomedical interventions to eliminate new HIV infections; however, uptake among gay, bisexual, and other men who have sex with men has been slow amidst growing concern in popular/social media that PrEP use will result in reduced condom use (i.e., risk compensation). We investigated demographic, behavioral, and psychosocial differences in willingness to use PrEP as well as the perceived impact of PrEP on participants' condom use in a sample of 206 highly sexually active HIV-negative gay and bisexual men. Nearly half (46.1 %) said they would be willing to take PrEP if it were provided at no cost. Although men willing to take PrEP (vs. others) reported similar numbers of recent casual male partners (<6 weeks), they had higher odds of recent receptive condomless anal sex (CAS)-i.e., those already at high risk of contracting HIV were more willing to take PrEP. Neither age, race/ethnicity, nor income were associated with willingness to take PrEP, suggesting equal acceptability among subpopulations that are experiencing disparities in HIV incidence. There was limited evidence to suggest men would risk compensate. Only 10 % of men who had not engaged in recent CAS felt that PrEP would result in them starting to have CAS. Men who had not tested for HIV recently were also significantly more likely than others to indicate willingness to take PrEP. Offering PrEP to men who test infrequently may serve to engage them more in routine HIV/STI testing and create a continued dialogue around sexual health between patient and provider in order to prevent HIV infection.

  6. PREP for Strong Bonds: A review of outcomes from a randomized clinical trial

    PubMed Central

    Allen, Elizabeth; Stanley, Scott; Rhoades, Galena; Markman, Howard

    2015-01-01

    To help address the relationship needs of service members, there have been a number of programs offered within active duty and veteran contexts. One program, offered within the Strong Bonds portfolio delivered by Army Chaplains, is PREP for Strong Bonds (PREP = the Prevention and Relationship Education Program). PREP has a number of empirically based and tested variants. This article reviews the disseminated research regarding results from a large randomized clinical trial designed to test the effectiveness of PREP for Strong Bonds. From a sample of 662 Army couples drawn from two sites, outcome papers have focused on different subsamples, marital outcomes, follow up time points, and moderators. Reviewing these disseminated outcomes, we conclude that PREP for Strong Bonds has significant divorce reduction effects at one site; these divorce effects were found at both one and two years post intervention, and were moderated by factors such as minority status, economic strain, and cohabitation history of the couple. In terms of marital quality outcomes, some modest overall effects were found pre to post intervention, but there were no overall marital quality outcome effects two years post intervention. However, marital quality outcomes are significantly moderated by infidelity and cohabitation history, with couples reporting these risk factors showing greater positive marital quality outcomes. These results to date are discussed in terms of clinical and research implications as well as directions for future work, such as examining longer term preventative effects. PMID:26366041

  7. NOS/NGS activities to support development of radio interferometric surveying techniques

    NASA Technical Reports Server (NTRS)

    Carter, W. E.; Dracup, J. F.; Hothem, L. D.; Robertson, D. S.; Strange, W. E.

    1980-01-01

    National Geodetic Survey activities towards the development of operational geodetic survey systems based on radio interferometry are reviewed. Information about the field procedures, data reduction and analysis, and the results obtained to date is presented.

  8. The Development and Deployment of a Maintenance Operations Safety Survey.

    PubMed

    Langer, Marie; Braithwaite, Graham R

    2016-11-01

    Based on the line operations safety audit (LOSA), two studies were conducted to develop and deploy an equivalent tool for aircraft maintenance: the maintenance operations safety survey (MOSS). Safety in aircraft maintenance is currently measured reactively, based on the number of audit findings, reportable events, incidents, or accidents. Proactive safety tools designed for monitoring routine operations, such as flight data monitoring and LOSA, have been developed predominantly for flight operations. In Study 1, development of MOSS, 12 test peer-to-peer observations were collected to investigate the practicalities of this approach. In Study 2, deployment of MOSS, seven expert observers collected 56 peer-to-peer observations of line maintenance checks at four stations. Narrative data were coded and analyzed according to the threat and error management (TEM) framework. In Study 1, a line check was identified as a suitable unit of observation. Communication and third-party data management were the key factors in gaining maintainer trust. Study 2 identified that on average, maintainers experienced 7.8 threats (operational complexities) and committed 2.5 errors per observation. The majority of threats and errors were inconsequential. Links between specific threats and errors leading to 36 undesired states were established. This research demonstrates that observations of routine maintenance operations are feasible. TEM-based results highlight successful management strategies that maintainers employ on a day-to-day basis. MOSS is a novel approach for safety data collection and analysis. It helps practitioners understand the nature of maintenance errors, promote an informed culture, and support safety management systems in the maintenance domain. © 2016, Human Factors and Ergonomics Society.

  9. The Development and Deployment of a Maintenance Operations Safety Survey

    PubMed Central

    Langer, Marie; Braithwaite, Graham R.

    2016-01-01

    Objective: Based on the line operations safety audit (LOSA), two studies were conducted to develop and deploy an equivalent tool for aircraft maintenance: the maintenance operations safety survey (MOSS). Background: Safety in aircraft maintenance is currently measured reactively, based on the number of audit findings, reportable events, incidents, or accidents. Proactive safety tools designed for monitoring routine operations, such as flight data monitoring and LOSA, have been developed predominantly for flight operations. Method: In Study 1, development of MOSS, 12 test peer-to-peer observations were collected to investigate the practicalities of this approach. In Study 2, deployment of MOSS, seven expert observers collected 56 peer-to-peer observations of line maintenance checks at four stations. Narrative data were coded and analyzed according to the threat and error management (TEM) framework. Results: In Study 1, a line check was identified as a suitable unit of observation. Communication and third-party data management were the key factors in gaining maintainer trust. Study 2 identified that on average, maintainers experienced 7.8 threats (operational complexities) and committed 2.5 errors per observation. The majority of threats and errors were inconsequential. Links between specific threats and errors leading to 36 undesired states were established. Conclusion: This research demonstrates that observations of routine maintenance operations are feasible. TEM-based results highlight successful management strategies that maintainers employ on a day-to-day basis. Application: MOSS is a novel approach for safety data collection and analysis. It helps practitioners understand the nature of maintenance errors, promote an informed culture, and support safety management systems in the maintenance domain. PMID:27411354

  10. Prioritizing Student Skill Development in the Small College Literature Survey

    ERIC Educational Resources Information Center

    Kalata, Kristianne

    2016-01-01

    This essay describes the successes and challenges of skills-based literature survey courses in the small liberal arts college setting of Westminster College (New Wilmington, PA). It considers the overall purpose of the survey in the skills-based English curriculum and then focuses on the integration of literary theory and creative writing as means…

  11. Application of Medical Intelligence Prep of the Environment: A Review of Operational Vignettes.

    PubMed

    Caci, Jennifer B

    2015-01-01

    Medical intelligence is an underused or sometimes misapplied tool in the protection of our Soldiers and the execution of nonkinetic operations. The somewhat improved infrastructure of the operational environment in Iraq and Afghanistan led to an inevitable sense of complacency in regard to the threat of disease nonbattle injury (DNBI). The picture changed somewhat in 2010 with the advent of the village stability program and the establishment of SOF camps in austere locations with degraded living situations rife with exposure risks. In addition, the increasing deployments to unstable locations around the globe, reminiscent of typical Special Operations Forces (SOF) missions before the Global War on Terrorism, indicate a need for better preparation for deployment from the standpoint of disease risk and force health protection. A knowledge gap has developed because we simply did not need to apply as stringent an evaluation of DNBI risk in environments where improved life support mitigated the risk for us. The tools necessary to decrease or even eliminate the impact of DNBI exist but they must be shared and implemented. This article will present four vignettes from current and former SOF Force Health Protection personnel starting with a simple method of executing Medical Intelligence Prep of the Environment (MIPOE) and highlighting situations in which it either was or could have been implemented to mitigate risk and decrease the impact on mission accomplishment and individual operators. A follow-on article will present vignettes of the successful application of MIPOE to nonkinetic operations.

  12. 34 CFR 406.31 - How does a State carry out the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 3 2011-07-01 2011-07-01 false How does a State carry out the State-Administered Tech... TECH-PREP EDUCATION PROGRAM What Conditions Must Be Met After a State Receives an Award? § 406.31 How does a State carry out the State-Administered Tech-Prep Education Program? (a) A State board...

  13. Does the Number of College Credits Earned in a Tech Prep and Postsecondary Enrollment Options Program Predict College Success?

    ERIC Educational Resources Information Center

    Meyer, Bruce A.

    2011-01-01

    The purpose of this study was to examine a Tech Prep Program located in Northwest Ohio and determine the degree to which college credits earned in high school through the Tech Prep and PSEO Programs predict college success and if there were any significant gender/race differences in credits earned and college success as well as high school…

  14. 34 CFR 406.31 - How does a State carry out the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 3 2012-07-01 2012-07-01 false How does a State carry out the State-Administered Tech... TECH-PREP EDUCATION PROGRAM What Conditions Must Be Met After a State Receives an Award? § 406.31 How does a State carry out the State-Administered Tech-Prep Education Program? (a) A State board...

  15. 34 CFR 406.31 - How does a State carry out the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 3 2014-07-01 2014-07-01 false How does a State carry out the State-Administered Tech... TECH-PREP EDUCATION PROGRAM What Conditions Must Be Met After a State Receives an Award? § 406.31 How does a State carry out the State-Administered Tech-Prep Education Program? (a) A State board...

  16. 34 CFR 406.31 - How does a State carry out the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 3 2013-07-01 2013-07-01 false How does a State carry out the State-Administered Tech... TECH-PREP EDUCATION PROGRAM What Conditions Must Be Met After a State Receives an Award? § 406.31 How does a State carry out the State-Administered Tech-Prep Education Program? (a) A State board...

  17. 34 CFR 406.31 - How does a State carry out the State-Administered Tech-Prep Education Program?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does a State carry out the State-Administered Tech... TECH-PREP EDUCATION PROGRAM What Conditions Must Be Met After a State Receives an Award? § 406.31 How does a State carry out the State-Administered Tech-Prep Education Program? (a) A State board...

  18. Gendered differences in the perceived risks and benefits of oral PrEP among HIV-serodiscordant couples in Kenya.

    PubMed

    Carroll, Jennifer J; Ngure, Kenneth; Heffron, Renee; Curran, Kathryn; Mugo, Nelly R; Baeten, Jared M

    2016-08-01

    Pre-exposure prophylaxis (PrEP) is effective for preventing HIV among HIV-serodiscordant heterosexual couples. Gender roles may influence perceived personal and social risks related to HIV-prevention behaviors and may affect use of PrEP. In this study, interviews and focus groups were conducted with 68 individuals from 34 mutually disclosed serodiscordant heterosexual partnerships in Thika, Kenya. Sociocultural factors that affect adherence to PrEP were explored using grounded analysis. Three factors were identified, which shape perceptions of PrEP: gendered power dynamics and control over decision-making in the household; conflicts between risk-reduction strategies and male sexual desire; culture-bound definitions of women's work. Adherence to PrEP in the Partners PrEP Study was high; however, participants articulated conflicting interests related to PrEP in connection with traditional gender roles. The successful delivery of PrEP will require understanding of key social factors, particularly related to gender and dyadic dynamics around HIV serostatus.

  19. Applying a PrEP Continuum of Care for Men Who Have Sex With Men in Atlanta, Georgia.

    PubMed

    Kelley, Colleen F; Kahle, Erin; Siegler, Aaron; Sanchez, Travis; Del Rio, Carlos; Sullivan, Patrick S; Rosenberg, Eli S

    2015-11-15

    Reductions in human immunodeficiency virus (HIV) incidence with pre-exposure prophylaxis (PrEP) for men who have sex with men (MSM) will require significant coverage of those at risk. We propose a simplified framework, similar to the HIV care continuum, to achieve protection with PrEP as follows: 1. At-risk MSM; 2. Awareness of and willingness to take PrEP; 3. Access to healthcare; 4. Receiving a prescription; and 5. Adhering to effective PrEP. We evaluated the PrEP care continuum on an Atlanta cohort of MSM and projected how many MSM might achieve protection from HIV. Even with optimistic estimates, few Atlanta MSM (15%) are projected to achieve protection from HIV with PrEP given the significant barriers described. Each continuum step represents an important point for intervention that could substantially increase the overall effectiveness of PrEP. In addition, novel strategies for PrEP delivery are needed to achieve the necessary effectiveness for Atlanta MSM at risk of HIV.

  20. 75 FR 13292 - Determination That HalfLytely and Bisacodyl Tablets Bowel Prep Kit (Containing 4 Bisacodyl...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    ... (polyethylene glycol (PEG) 3350, sodium chloride, sodium bicarbonate, and potassium chloride for oral solution... applications (ANDAs) for bowel prep kits containing PEG-3350, sodium chloride, sodium bicarbonate, and... PREP KIT (PEG-3350, sodium chloride, sodium bicarbonate, and potassium chloride for oral solution and...

  1. New Lessons About Tech Prep Implementation. In Essence: Key Findings from the National Research Center for Career and Technical Education.

    ERIC Educational Resources Information Center

    Naylor, Michele

    The evolution of eight Tech Prep consortia since reauthorization of federal Tech Prep legislation in 1998 was examined in a 4-year longitudinal study. Cross-consortium changes were identified through field visits and personal interviews between 1998-2001 with a wide range of stakeholders, especially administrators, faculty, and students.…

  2. "When We Remix...We Remake!!!" Reflections on Collaborative Ethnography, the New Digital Ethic, and Test Prep

    ERIC Educational Resources Information Center

    Leary, Chris

    2007-01-01

    This article describes two very different projects undertaken in the same basic writing course: collaborative ethnography and ACT test prep. At first glance, it appears that the work on collaborative ethnography accomplished our goal of creating better, more self-conscious writers while the work on test prep achieved our goal of creating better…

  3. Applying a PrEP Continuum of Care for Men Who Have Sex With Men in Atlanta, Georgia

    PubMed Central

    Kelley, Colleen F.; Kahle, Erin; Siegler, Aaron; Sanchez, Travis; del Rio, Carlos; Sullivan, Patrick S.; Rosenberg, Eli S.

    2015-01-01

    Reductions in human immunodeficiency virus (HIV) incidence with pre-exposure prophylaxis (PrEP) for men who have sex with men (MSM) will require significant coverage of those at risk. We propose a simplified framework, similar to the HIV care continuum, to achieve protection with PrEP as follows: 1. At-risk MSM; 2. Awareness of and willingness to take PrEP; 3. Access to healthcare; 4. Receiving a prescription; and 5. Adhering to effective PrEP. We evaluated the PrEP care continuum on an Atlanta cohort of MSM and projected how many MSM might achieve protection from HIV. Even with optimistic estimates, few Atlanta MSM (15%) are projected to achieve protection from HIV with PrEP given the significant barriers described. Each continuum step represents an important point for intervention that could substantially increase the overall effectiveness of PrEP. In addition, novel strategies for PrEP delivery are needed to achieve the necessary effectiveness for Atlanta MSM at risk of HIV. PMID:26270691

  4. Communications for Lifelong Success I and II (Tech Prep English I and II). Pilot Test Materials for Pendleton High School, Pendleton, South Carolina. Draft.

    ERIC Educational Resources Information Center

    Turlington, Anita; And Others

    These instructional materials include six supplementary units for Tech Prep English I (grade 9) and six assignments for Tech Prep English II (grade 10). The Tech Prep English I units have these components: unit objectives, introduction, and follow-up exercises. Topics include goal setting, problem solving and decision making, listening and reading…

  5. Efficiency of augmented p-rep designs in multi-environmental trials.

    PubMed

    Moehring, Jens; Williams, Emlyn R; Piepho, Hans-Peter

    2014-05-01

    The paper shows that unreplicated designs in multi-environmental trials are most efficient. If replication per environment is needed then augmented p-rep designs outperform augmented and replicated designs in triticale and maize. In plant breeding, augmented designs with unreplicated entries are frequently used for early generation testing. With limited amount of seed, this design allows to use a maximum number of environments in multi-environmental trials (METs). Check plots enable the estimation of block effects, error variances and a connection of otherwise unconnected trials in METs. Cullis et al. (J Agri Biol Environ Stat 11:381-393, 2006) propose to replace check plots from a grid-plot design by plots of replicated entries leading to partially replicated (p-rep) designs. Williams et al. (Biom J 53:19-27, 2011) apply this idea to augmented designs (augmented p-rep designs). While p-rep designs are increasingly used in METs, a comparison of the efficiency of augmented p-rep designs and augmented designs in the range between replicated and unreplicated designs in METs is lacking. We simulated genetic effects and allocated them according to these four designs to plot yields of a triticale and a maize uniformity trial. The designs varied in the number of environments, but have a fixed number of entries and total plots. The error model and the assumption of fixed or random entry effects were varied in simulations. We extended our simulation for the triticale data by including correlated entry effects which are common in genomic selection. Results show an advantage of unreplicated and augmented p-rep designs and a preference for using random entry effects, especially in case of correlated effects reflecting relationships among entries. Spatial error models had minor advantages compared to purely randomization-based models.

  6. Parents' childhood fever management: community survey and instrument development.

    PubMed

    Walsh, Anne; Edwards, Helen; Fraser, Jenny

    2008-08-01

    This paper is a report of a study to explore Australian parents' knowledge, beliefs, practices and information sources about fever management and develop a scale to measure parents' fever management practices. Parental fever phobia and overuse of antipyretics to reduce fever continue. No scales to measure parents' fever management practices are available. A community-based, postal survey was carried out in 2005 with 401 Australian parents of well children aged 6 months-5 years. Respondents were recruited through advertising (48.4%), face-to-face (26.4%) and snowball (24.4%) methods. A 33-item instrument was developed; construct and content validity were determined by an expert panel and item reliability by test-retest. Moderate fever (40.0 +/- 1.0 degrees C) was reported to be harmful (88%), causing febrile convulsions (77.7%). Usual practices targeted temperature reduction, antipyretic administration (87.8%), temperature monitoring (52.5%). Fewer evidence-based practices, such as encouraging fluids (49.0%) and light clothing (43.8%), were reported. Positive changes over time (36.4%) included less concern and delayed or reduced antipyretic use. Negative practice changes (22.7%) included greater concern and increased antipyretic use. Medical advice was sought for illness symptoms (48.7%) and high (37.4%) or persistent (41.5%) fevers. Fever management was learnt from doctors, family and friends and working experience, while receiving conflicting information (41.9%) increased concerns and created uncertainty about best practice. Parents need consistent evidence-based information about childhood fever management. The Parental Fever Management Scale requires further testing with different populations and in different cultures and healthcare systems to evaluate its usefulness in nursing practice and research.

  7. PrEP implementation: moving from trials to policy and practice.

    PubMed

    Cáceres, Carlos F; O'Reilly, Kevin R; Mayer, Kenneth H; Baggaley, Rachel

    2015-01-01

    It is increasingly clear that the HIV response will not be sustainable if the number of infections is not significantly reduced. For two decades, research has been ongoing to identify new behavioural and biomedical strategies to prevent HIV infection. In the past few years, the efficacy of several new strategies has been demonstrated, including oral pre-exposure prophylaxis (PrEP; i.e. daily use of tenofovir/emtricitabine). Because several social, political and logistic barriers remain, however, optimal PrEP implementation will require a better dissemination of new evidence in a number of areas and additional implementation research from various disciplinary perspectives (i.e. social science, policy and ethics; health systems; and economics, including cost-effectiveness studies). Discussion of new evidence on those topics, as well as case studies of potential PrEP implementation in diverse environments, can improve the understanding of the role that PrEP may play in addressing the global HIV/AIDS epidemic.In light of these needs, the Network for Multidisciplinary Studies in ARV-based HIV Prevention (NEMUS) and the World Health Organization (WHO) were honoured to co-organize a special issue of JIAS aimed at contributing to a scholarly discussion of current conditions surrounding PrEP implementation, potential impact and efficiency, social science concerns and the study of PrEP implementation in specific country cases. The papers included in this monograph identify and cover many of the main aspects of the complex yet promising discussions around PrEP implementation today. This is a collection of timely contributions from global leaders in HIV research and policy that addresses geographic diversity, uses a trans-disciplinary approach and covers a variety of the complex issues raised by PrEP. As this publication will become accessible to all, we hope that it will remain a valuable resource for policy makers, programme managers, researchers and activists around the

  8. Decreasing Divorce in Army Couples: Results from a Randomized Controlled Trial using PREP for Strong Bonds

    PubMed Central

    Stanley, Scott M.; Allen, Elizabeth S.; Markman, Howard J.; Rhoades, Galena K.; Prentice, Donnella L.

    2010-01-01

    Findings from a large, randomized controlled trial of couple education are presented in this brief report. Married Army couples were assigned to either PREP for Strong Bonds (n = 248) delivered by Army chaplains or to a no-treatment control group (n = 228). One year after the intervention, couples who received PREP for Strong Bonds had 1/3 the rate of divorce of the control group. Specifically, 6.20% of the control group divorced while 2.03% of the intervention group divorced. These findings suggest that couple education can reduce the risk of divorce, at least in the short run with military couples. PMID:20634994

  9. Polish Vocabulary Development in 2-Year-Olds: Comparisons with English Using the Language Development Survey

    ERIC Educational Resources Information Center

    Rescorla, Leslie; Constants, Holly; Bialecka-Pikul, Marta; Stepien-Nycz, Malgorzata; Ochal, Anna

    2017-01-01

    Purpose: The objective of this study was to compare vocabulary size and composition in 2-year-olds learning Polish or English as measured by the Language Development Survey (LDS; Rescorla, 1989). Method: Participants were 199 Polish toddlers (M = 24.14 months, SD = 0.35) and 422 U.S. toddlers (M = 24.69 months, SD = 0.78). Results: Test-retest…

  10. Attitudes Towards PrEP and Anticipated Condom Use Among Concordant HIV-Negative and HIV-Discordant Male Couples

    PubMed Central

    Chakravarty, Deepalika; Bircher, Anja E.; Campbell, Chadwick K.; Grisham, Kirk; Neilands, Torsten B.; Wilson, Patrick A.; Dworkin, Shari

    2015-01-01

    Abstract Since the July 2012 approval by the FDA of emtricitabine/ tenofovir disoproxil fumarate (Truvada) for use as pre-exposure prophylaxis (PrEP) against HIV, its feasibility and acceptability has been under study. HIV-discordant couples are likely targets for PrEP but little is known about how this new prevention tool impacts relationships. We examined, among gay male couples, the acceptability of individual and partner use of PrEP and intentions to use condoms with primary and outside partners in the context of PrEP use. Data are from two independent samples of couples recruited in the San Francisco bay area and New York City—a qualitative one (N=48 couples) between March and November, 2011, and a quantitative one (N=171 couples) between June, 2012 and May, 2013. Data were categorized by couple HIV status and general linear models; chi-square tests of independence were used to examine condom-use intentions with primary and outside partners, by sexual risk profile, and race. Almost half of the HIV-negative couples felt PrEP was a good HIV prevention strategy for themselves and their partner. Over half reported that they would not change their current condom use if they or their partner were taking PrEP. However, approximately 30% of HIV-negative couples reported that they would stop using condoms or use them less with primary and outside partners if they were on PrEP or if their partner was on PrEP. A large percentage of couples view PrEP positively. However, to ensure safety for both partners, future programing must consider those who intend not to use condoms while on PrEP. PMID:26057304

  11. Attitudes Towards PrEP and Anticipated Condom Use Among Concordant HIV-Negative and HIV-Discordant Male Couples.

    PubMed

    Hoff, Colleen C; Chakravarty, Deepalika; Bircher, Anja E; Campbell, Chadwick K; Grisham, Kirk; Neilands, Torsten B; Wilson, Patrick A; Dworkin, Shari

    2015-07-01

    Since the July 2012 approval by the FDA of emtricitabine/ tenofovir disoproxil fumarate (Truvada) for use as pre-exposure prophylaxis (PrEP) against HIV, its feasibility and acceptability has been under study. HIV-discordant couples are likely targets for PrEP but little is known about how this new prevention tool impacts relationships. We examined, among gay male couples, the acceptability of individual and partner use of PrEP and intentions to use condoms with primary and outside partners in the context of PrEP use. Data are from two independent samples of couples recruited in the San Francisco bay area and New York City-a qualitative one (N=48 couples) between March and November, 2011, and a quantitative one (N=171 couples) between June, 2012 and May, 2013. Data were categorized by couple HIV status and general linear models; chi-square tests of independence were used to examine condom-use intentions with primary and outside partners, by sexual risk profile, and race. Almost half of the HIV-negative couples felt PrEP was a good HIV prevention strategy for themselves and their partner. Over half reported that they would not change their current condom use if they or their partner were taking PrEP. However, approximately 30% of HIV-negative couples reported that they would stop using condoms or use them less with primary and outside partners if they were on PrEP or if their partner was on PrEP. A large percentage of couples view PrEP positively. However, to ensure safety for both partners, future programing must consider those who intend not to use condoms while on PrEP.

  12. The future of PrEP among transgender women: the critical role of gender affirmation in research and clinical practices.

    PubMed

    Sevelius, Jae M; Deutsch, Madeline B; Grant, Robert

    2016-01-01

    Globally, transgender ("trans") women are one of the key populations most disproportionately impacted by HIV. Pre-exposure prophylaxis (PrEP) is the newest and most promising biomedical HIV prevention intervention to date. This paper reviews relevant literature to describe the current state of the science and describes the potential role of PrEP among trans women, including a discussion of unique considerations for maximizing the impact of PrEP for this vulnerable population. Available information, including but not limited to existing scientific literature, about trans women and PrEP was reviewed and critiqued based on author expertise, including PrEP clinical trials and rollout. To date, PrEP demonstration projects and clinical trials have largely excluded trans women, or have not included them in a meaningful way. Data collection strategies that fail to identify trans women in clinical trials and research further limit the ability to draw conclusions about trans women's unique needs and devise strategies to meet them. Gender-affirming providers and clinic environments are essential components of any sexual health programme that aims to serve trans women, as they will largely avoid settings that may result in stigmatizing encounters and threats to their identities. While there is currently no evidence to suggest drug-drug interactions between PrEP and commonly used feminizing hormone regimens, community concerns about potential interactions may limit interest in and uptake of PrEP among trans women. In scaling up PrEP for trans women, it is essential to engage trans communities, utilize trans-inclusive research and marketing strategies and identify and/or train healthcare providers to provide gender-affirming healthcare to trans women, including transition-related care such as hormone provision. PrEP implementation guidelines must consider and address trans women's unique barriers and facilitators to uptake and adherence.

  13. Views of policymakers, healthcare workers and NGOs on HIV pre-exposure prophylaxis (PrEP): a multinational qualitative study.

    PubMed

    Wheelock, Ana; Eisingerich, Andreas B; Gomez, Gabriela B; Gray, Emily; Dybul, Mark R; Piot, Peter

    2012-01-01

    To examine policymakers and providers' views on pre-exposure prophylaxis (PrEP) and their willingness to support its introduction, to inform policy and practice in this emerging field. Semistructured qualitative interview study. Peru, Ukraine, India, Kenya, Uganda, Botswana and South Africa. 35 policymakers, 35 healthcare workers and 21 non-governmental organisation representatives involved in HIV prevention. Six themes emerged from the data: (1) perceived HIV prevention landscape: prevention initiatives needed to be improved and expanded; (2) PrEP awareness: 50 of 91 participants had heard of PrEP; (3) benefits of PrEP: one component of the combination prevention arsenal that could help prioritise HIV prevention, empower key populations and result in economic gains; (4) challenges of PrEP: regimen complexity, cost and cost-effectiveness, risk compensation, efficacy and effectiveness, stigmatisation and criminalisation, information and training and healthcare system capacity; (5) programmatic considerations: user eligibility, communication strategy, cost, distribution, medication and HIV testing compliance and (6) early versus late implementation: participants were divided as to whether they would support an early introduction of PrEP in their country or would prefer to wait until it has been successfully implemented in other countries, with around half of those we spoke to supporting each option. Very few said they would not support PrEP at all. Despite the multiple challenges identified, there was general willingness to support the introduction of PrEP. Yet, strengthening existing HIV prevention efforts was also deemed necessary. Our results suggest that an effective PrEP programme would be delivered in healthcare facilities and involve non-governmental organisations and the community and consider the needs of mobile populations. Comprehensive information packages and training for users and providers would be critical. The cost of PrEP would be affordable and

  14. Views of policymakers, healthcare workers and NGOs on HIV pre-exposure prophylaxis (PrEP): a multinational qualitative study

    PubMed Central

    Eisingerich, Andreas B; Gomez, Gabriela B; Gray, Emily; Dybul, Mark R; Piot, Peter

    2012-01-01

    Objectives To examine policymakers and providers' views on pre-exposure prophylaxis (PrEP) and their willingness to support its introduction, to inform policy and practice in this emerging field. Design Semistructured qualitative interview study. Setting Peru, Ukraine, India, Kenya, Uganda, Botswana and South Africa. Participants 35 policymakers, 35 healthcare workers and 21 non-governmental organisation representatives involved in HIV prevention. Results Six themes emerged from the data: (1) perceived HIV prevention landscape: prevention initiatives needed to be improved and expanded; (2) PrEP awareness: 50 of 91 participants had heard of PrEP; (3) benefits of PrEP: one component of the combination prevention arsenal that could help prioritise HIV prevention, empower key populations and result in economic gains; (4) challenges of PrEP: regimen complexity, cost and cost-effectiveness, risk compensation, efficacy and effectiveness, stigmatisation and criminalisation, information and training and healthcare system capacity; (5) programmatic considerations: user eligibility, communication strategy, cost, distribution, medication and HIV testing compliance and (6) early versus late implementation: participants were divided as to whether they would support an early introduction of PrEP in their country or would prefer to wait until it has been successfully implemented in other countries, with around half of those we spoke to supporting each option. Very few said they would not support PrEP at all. Conclusions Despite the multiple challenges identified, there was general willingness to support the introduction of PrEP. Yet, strengthening existing HIV prevention efforts was also deemed necessary. Our results suggest that an effective PrEP programme would be delivered in healthcare facilities and involve non-governmental organisations and the community and consider the needs of mobile populations. Comprehensive information packages and training for users and providers

  15. The future of PrEP among transgender women: the critical role of gender affirmation in research and clinical practices

    PubMed Central

    Sevelius, Jae M; Deutsch, Madeline B; Grant, Robert

    2016-01-01

    Introduction Globally, transgender (“trans”) women are one of the key populations most disproportionately impacted by HIV. Pre-exposure prophylaxis (PrEP) is the newest and most promising biomedical HIV prevention intervention to date. This paper reviews relevant literature to describe the current state of the science and describes the potential role of PrEP among trans women, including a discussion of unique considerations for maximizing the impact of PrEP for this vulnerable population. Methods Available information, including but not limited to existing scientific literature, about trans women and PrEP was reviewed and critiqued based on author expertise, including PrEP clinical trials and rollout. Results To date, PrEP demonstration projects and clinical trials have largely excluded trans women, or have not included them in a meaningful way. Data collection strategies that fail to identify trans women in clinical trials and research further limit the ability to draw conclusions about trans women's unique needs and devise strategies to meet them. Gender-affirming providers and clinic environments are essential components of any sexual health programme that aims to serve trans women, as they will largely avoid settings that may result in stigmatizing encounters and threats to their identities. While there is currently no evidence to suggest drug-drug interactions between PrEP and commonly used feminizing hormone regimens, community concerns about potential interactions may limit interest in and uptake of PrEP among trans women. Conclusions In scaling up PrEP for trans women, it is essential to engage trans communities, utilize trans-inclusive research and marketing strategies and identify and/or train healthcare providers to provide gender-affirming healthcare to trans women, including transition-related care such as hormone provision. PrEP implementation guidelines must consider and address trans women's unique barriers and facilitators to uptake and

  16. Multidisciplinary aerospace design optimization: Survey of recent developments

    NASA Technical Reports Server (NTRS)

    Sobieszczanski-Sobieski, Jaroslaw; Haftka, Raphael T.

    1995-01-01

    The increasing complexity of engineering systems has sparked increasing interest in multidisciplinary optimization (MDO). This paper presents a survey of recent publications in the field of aerospace where interest in MDO has been particularly intense. The two main challenges of MDO are computational expense and organizational complexity. Accordingly the survey is focussed on various ways different researchers use to deal with these challenges. The survey is organized by a breakdown of MDO into its conceptual components. Accordingly, the survey includes sections on Mathematical Modeling, Design-oriented Analysis, Approximation Concepts, Optimization Procedures, System Sensitivity, and Human Interface. With the authors' main expertise being in the structures area, the bulk of the references focus on the interaction of the structures discipline with other disciplines. In particular, two sections at the end focus on two such interactions that have recently been pursued with a particular vigor: Simultaneous Optimization of Structures and Aerodynamics, and Simultaneous Optimization of Structures Combined With Active Control.

  17. Development of the Senior Concerns Survey: An Exploratory Factor Analysis.

    ERIC Educational Resources Information Center

    Pistilli, Matthew D.; Taub, Deborah J.; Bennett, Deborah E.

    2003-01-01

    Created and tested the Senior Concerns Survey. An exploratory factor analysis revealed four areas of concern for college seniors: career related concerns, change and loss related concerns, graduate/professional school related concerns, and support related concerns. (EV)

  18. Developing an Internet-based Survey to Collect Program Cost Data

    ERIC Educational Resources Information Center

    Caffray, Christine M.; Chatterji, Pinka

    2009-01-01

    This manuscript describes the development and testing of an Internet-based cost survey that was designed by the authors for the National Assembly on School-Based Health Care (NASBHC) to capture the costs of school-based health programs. The intent of the survey was twofold. First, the survey was designed to collect comprehensive data on costs in a…

  19. The Development of Technology Enhanced Learning: Findings from a 2008 Survey of UK Higher Education Institutions

    ERIC Educational Resources Information Center

    Jenkins, Martin; Browne, Tom; Walker, Richard; Hewitt, Roger

    2011-01-01

    This article summarises the key findings from a UK survey of higher education institutions, focusing on the development of technology enhanced learning (TEL). TEL is defined as any online facility or system that directly supports learning and teaching. The 2008 survey builds upon previous UCISA surveys conducted in 2001, 2003 and 2005 and for…

  20. The School Counselor Leadership Survey: Instrument Development and Exploratory Factor Analysis

    ERIC Educational Resources Information Center

    Young, Anita; Bryan, Julia

    2015-01-01

    This study examined the factor structure of the School Counselor Leadership Survey (SCLS). Survey development was a threefold process that resulted in a 39-item survey of 801 school counselors and school counselor supervisors. The exploratory factor analysis indicated a five-factor structure that revealed five key dimensions of school counselor…

  1. The School Counselor Leadership Survey: Instrument Development and Exploratory Factor Analysis

    ERIC Educational Resources Information Center

    Young, Anita; Bryan, Julia

    2015-01-01

    This study examined the factor structure of the School Counselor Leadership Survey (SCLS). Survey development was a threefold process that resulted in a 39-item survey of 801 school counselors and school counselor supervisors. The exploratory factor analysis indicated a five-factor structure that revealed five key dimensions of school counselor…

  2. Willingness to use pre-exposure prophylaxis for HIV prevention among men who have sex with men in Malaysia: Findings from an online survey

    PubMed Central

    Pang, Joselyn; Wei, Clayton Koh Thuan; Yee, Ilias Adam; Wang, Bangyuan; Cassolato, Matteo

    2017-01-01

    Objective We examined willingness to use pre-exposure prophylaxis (PrEP) for HIV prevention among men who have sex with men (MSM) in Malaysia. Methods An online survey of 990 MSM was conducted between March and April 2016. Eligibility criteria included being biological male, Malaysian citizen, 18 years of age or above, identifying as MSM, and being HIV negative or unknown status. Participants’ demographics, sexual and drug use behaviors, attitudes towards PrEP, and preferences regarding future access to PrEP were collected. Bivariate analysis and logistic regression were performed to determine factors associated with willingness to use PrEP. Results Fewer than half of participants (44%) knew about PrEP before completing the survey. Overall, 39% of the sample were willing to take PrEP. Multivariate logistic regression indicated that Malay men (AOR: 1.73, 95% CI:1.12, 2.70), having 2 or more male anal sex partners in the past 6 months (AOR: 1.98, 95% CI: 1.29, 3.05), previous knowledge of PrEP (AOR: 1.40, 95%CI: 1.06, 1.86), lack of confidence in practising safer sex (AOR: 1.36, 95% CI: 1.02, 1.81), and having ever paid for sex with a male partner (AOR: 1.39, 95% CI: 1.01, 1.91) were independently associated with greater willingness to use PrEP, while men who identified as heterosexual were less willing to use PrEP (AOR, 0.36, 95% CI: 0.13, 0.97). Majority of participants preferred to access PrEP at affordable cost below 100 Malaysian Ringgit (USD25) per month from community based organisations followed by private or government hospitals. Conclusions Overall, MSM in Malaysia reported a relatively low level of willingness to use PrEP, although willingness was higher among those previously aware of PrEP. There is a need to provide PrEP at affordable cost, increase demand and awareness of PrEP, and to provide access to this preventative medication via diverse, integrated and tailored sexual health services. PMID:28902857

  3. Scientific Growth and Identity Development during a Postbaccalaureate Program: Results from a Multisite Qualitative Study

    PubMed Central

    Remich, Robin; Naffziger-Hirsch, Michelle E.; Gazley, J. Lynn; McGee, Richard

    2016-01-01

    This report builds upon our previous study, which described five patterns of why college graduates join National Institutes of Health (NIH)-funded diversity-focused Postbaccalaureate Research Education Programs (PREP). A 2015 report from the NIH showed that a high fraction of PREP participants matriculate into PhD and MD/PhD programs. This current study reveals how participants change during PREP, the program elements that facilitate change, and how identity as a graduate student and future scientist develops. Data come from in-depth interviews done at the beginning and end of PREP with 48 individuals from seven PREP programs. Results reveal three domains of development: academics, research, and presentation of oneself; each domain contains a developmental continuum. Key attributes of PREP enabling development include opportunities to attend graduate-level classes and seminars; time to practice reading literature; extended lab time with one’s own project; high and explicit expectations from mentors; and multiple opportunities to talk about science and improve communication skills. PREP enabled participants to develop their identities as graduate students and to anticipate being seen by others as highly prepared for PhD training. After PREP, 85% (n = 41) started the PhD or MD/PhD, making PREP an intervention approach with great potential to broaden participation in biomedical PhD programs. PMID:27496357

  4. Scientific Growth and Identity Development during a Postbaccalaureate Program: Results from a Multisite Qualitative Study.

    PubMed

    Remich, Robin; Naffziger-Hirsch, Michelle E; Gazley, J Lynn; McGee, Richard

    2016-01-01

    This report builds upon our previous study, which described five patterns of why college graduates join National Institutes of Health (NIH)-funded diversity-focused Postbaccalaureate Research Education Programs (PREP). A 2015 report from the NIH showed that a high fraction of PREP participants matriculate into PhD and MD/PhD programs. This current study reveals how participants change during PREP, the program elements that facilitate change, and how identity as a graduate student and future scientist develops. Data come from in-depth interviews done at the beginning and end of PREP with 48 individuals from seven PREP programs. Results reveal three domains of development: academics, research, and presentation of oneself; each domain contains a developmental continuum. Key attributes of PREP enabling development include opportunities to attend graduate-level classes and seminars; time to practice reading literature; extended lab time with one's own project; high and explicit expectations from mentors; and multiple opportunities to talk about science and improve communication skills. PREP enabled participants to develop their identities as graduate students and to anticipate being seen by others as highly prepared for PhD training. After PREP, 85% (n = 41) started the PhD or MD/PhD, making PREP an intervention approach with great potential to broaden participation in biomedical PhD programs.

  5. Development of a Prototype of an Army Model Exit Survey

    DTIC Science & Technology

    1991-07-01

    TERMS (Continue on reverse if necessary and identify by block number) FIELD GROUP SUB-GROUP " Downsize Needs assessment, Ex4it survey- Optical mark...research program on downsizing the U.S. Army. The program, sponsored by the U.S. Army Research Institute for tc Behavioial and Social Sci- ences...included a review of downsizing literature, analysis of existing data bases for information on downsizing , and surveys assessing the impact of force

  6. Harassment in Workplace Among School Teachers: Development of Survey

    PubMed Central

    Russo, Andrea; Milić, Ranko; Knežević, Bojana; Mulić, Rosanda; Mustajbegović, Jadranka

    2008-01-01

    Aim To study the incidence of harassment in the workplace among teachers at primary and secondary schools. Methods We analyzed the existing questionnaires on harassment in the workplace and developed a new one was to specifically address harassment of teachers in the public education sector. The questionnaire was then experimentally applied to a sample of 764 primary and secondary school teachers in Split Dalmatia County, Croatia. It included three scales –exposure to harassment, witnessing harassment, and disturbance by harassment. Validity of the three scales was examined by factor analysis. Results All three scales showed satisfactory metric characteristics: Cronbach α coefficient was 0.93 for exposure scale, 0.95 for witnessing scale, and 0.97 for disturbance scale. Out of 764 teachers surveyed, 164 (22.4%) were exposed to and 192 (31.7%) witnessed different kinds of harassment in the previous 12 months. There were significantly more of those who experienced harassment as witnesses (χ21 = 249.301; P < 0.001) than as direct victims. Eighty-six teachers (11.5%) reported having psychological and 76 (10.1%) physical health problems caused by their work. Exclusion as a consequence of harassment disturbed women more than men (χ21 = 5.27; P = 0.022). Those who were exposed to harassment had significantly lower median age (42; range 23-68) than those who were not exposed (45; range 23-65) (U = 31401.50; z = 2.129; P = 0.033). Conclusion The questionnaire registered wide spectrum of harassment types, indicating the need for continuous monitoring and systematic work on the prevention of these phenomena. The study showed that exposure to harassment is associated with age, indicating that younger teachers should be the target population for detection and prevention of workplace harassment. PMID:18717002

  7. 1981 national survey of compensation paid scientists and engineers engaged in research and development activities

    SciTech Connect

    Not Available

    1981-12-01

    The results of a compensation survey conducted by the Columbus Laboratories of Battelle are presented. The survey was entitled A National Survey of Compensation Paid to Scientists and Engineers Engaged in Research and Development Activities. Information is included on the: sampling procedures; basic data for survey analysis; beginning salaries for recent graduates with bachelor, master, or doctorate degrees; salary trends; geographic analysis; interpretation of results; and salary tables. (LCL)

  8. Developmental validation of the PrepFiler Forensic DNA Extraction Kit for extraction of genomic DNA from biological samples.

    PubMed

    Brevnov, Maxim G; Pawar, Hemant S; Mundt, Janna; Calandro, Lisa M; Furtado, Manohar R; Shewale, Jaiprakash G

    2009-05-01

    The PrepFiler Forensic DNA Extraction Kit enables isolation of genomic DNA from a variety of biological samples. The kit facilitates reversible binding of DNA with magnetic particles resulting in high DNA recovery from samples with very low and high quantities of biological materials: 0.1 and 40 microL of human blood (donor 2) provided 14 and 2883 ng of DNA, respectively. Following the revised SWGDAM guidelines, performance of the developed method was investigated using different sample types including saliva on swabs, semen stains on cotton fabric, samples exposed to environment, samples with polymerase chain reaction (PCR) inhibitors, blood stains (on denim, cotton cloth, and FTA paper), and touch evidence-type samples. DNA yields for all samples tested were equal or better than those obtained by both phenol-chloroform extraction and commercial kits tested. DNA obtained from these samples was free of detectable PCR inhibitors. Short tandem repeat profiles were complete, conclusive, and devoid of PCR artifacts.

  9. The promise and peril of pre-exposure prophylaxis (PrEP): using social science to inform prep interventions among female sex workers.

    PubMed

    Syvertsen, Jennifer L; Robertson Bazzi, Angela M; Scheibe, Andrew; Adebajo, Sylvia; Strathdee, Steffanie A; Wechsberg, Wendee M

    2014-09-01

    Advances in biomedical interventions to prevent HIV offer great promise in reducing the number of new infections across sub- Saharan Africa, particularly among vulnerable populations such as female sex workers. Several recent trials testing pre-exposure prophylaxis (PrEP) have demonstrated efficacy, although others have been stopped early for futility. Given the importance and complexities of social and behavioural factors that influence biomedical approaches to prevention, we discuss several key areas of consideration moving forward, including trial participation, adherence strategies, social relationships, and the structural factors that shape PrEP interest, use, and potential effectiveness among female sex workers in sub-Saharan Africa. Our review highlights the importance of involving social scientists in clinical and community-based research on PrEP. We advocate for a shift away from a singular "re-medicalization" of the HIV epidemic to that of a "reintegration" of interdisciplinary approaches to prevention that could benefit female sex workers and other key populations at risk of acquiring HIV.

  10. The Promise and Peril of Pre-Exposure Prophylaxis (PrEP): Using Social Science to Inform PrEP Interventions among Female Sex Workers

    PubMed Central

    Syvertsen, Jennifer L.; Bazzi, Angela M. Robertson; Scheibe, Andrew; Adebajo, Sylvia; Strathdee, Steffanie A.; Wechsberg, Wendee M.

    2015-01-01

    Advances in biomedical interventions to prevent HIV offer great promise in reducing the number of new infections across sub-Saharan Africa, particularly among vulnerable populations such as female sex workers. Several recent trials testing pre-exposure prophylaxis (PrEP) have demonstrated efficacy, although others have been stopped early for futility. Given the importance and complexities of social and behavioural factors that influence biomedical approaches to prevention, we discuss several key areas of consideration moving forward, including trial participation, adherence strategies, social relationships, and the structural factors that shape PrEP interest, use, and potential effectiveness among female sex workers in sub-Saharan Africa. Our review highlights the importance of involving social scientists in clinical and community-based research on PrEP. We advocate for a shift away from a singular “re-medicalization” of the HIV epidemic to that of a “reintegration” of interdisciplinary approaches to prevention that could benefit female sex workers and other key populations at risk of acquiring HIV. PMID:26050379

  11. Teacher Development Program for ATP 2000. Project Report.

    ERIC Educational Resources Information Center

    Sutphin, Dean; And Others

    Agri Tech Prep 2000 (ATP 2000) is a 4-year tech prep program linking high school and postsecondary curricula designed to prepare New York students for careers in agriculture or acceptance into a college program in agriculture. Because teacher development was designated an integral project component for fiscal year 1991-1992, a weeklong teacher…

  12. A Model for Curriculum Development in Rural Schools.

    ERIC Educational Resources Information Center

    Phillips, Douglas

    Using the Biomedical Sciences Preparatory Program (BioPrep) for illustration, this paper discusses an approach to educational improvement through the development of curriculum that emphasizes experiential learning and the involvement of students in real-life problems. Opening sections describe BioPrep, a program designed to prepare rural high…

  13. Moving beyond Test-Prep Pedagogy: Dialoguing with Multicultural Preservice Teachers for a Quality Education

    ERIC Educational Resources Information Center

    Rodríguez, Louie F.

    2013-01-01

    In a "post-NCLB era," the schooling experiences of mostly low-income students of color continue to be consumed by a test-prep pedagogy--narrowed curriculum, low expectations, and ignored relationships. In this article the author describes a pedagogical approach using educational dialogues to engage preservice teachers to critically…

  14. School Science Prep Room Designs Fail to Deliver--A Special Report

    ERIC Educational Resources Information Center

    Hammond, James; Piggott, Andy

    2010-01-01

    A special report has been published aimed at reducing the number of poorly designed and equipped prep rooms specified by architects who have little or no experience in what is a very specialised area. Produced by school science equipment manufacturer, Gratnells, this report is the first step of its new "Architect Connection" initiative, a…

  15. OsmoPrep-associated Gastritis: A Histopathologic Mimic of Iron Pill Gastritis and Mucosal Calcinosis.

    PubMed

    Matsukuma, Karen; Gui, Dorina; Olson, Kristin A; Tejaswi, Sooraj; Clayton, Erica F; Thai, Anne

    2016-11-01

    We have identified 8 cases of gastritis characterized by the presence of purple to black granular deposits in the superficial mucosa associated with marked reactive epithelial changes. In each case, the patient had taken OsmoPrep, a tablet form of sodium phosphate used for bowel preparation just before upper endoscopy and had undergone concurrent colonoscopy. Endoscopic findings ranged from normal gastric mucosa to severe inflammation, congestion, and friability. No other gastrointestinal sites were noted to contain the deposits or show similar mucosal injury. On initial histologic review, the deposits raised the differential diagnosis of elemental iron and mucosal calcinosis. However, none of the patients was noted to be taking iron supplements, and none had a history of renal disease or other cause of calcium dysmetabolism. Histochemical stains revealed the deposits were negative on Perls' iron stain (8/8 cases), positive on von Kossa stain (7/8 cases), and negative on Alizarin Red stain (8/8 cases)-a histochemical profile compatible with sodium phosphate but inconsistent with mucosal calcium. A crushed OsmoPrep tablet was subjected to processing and demonstrated similar histologic features and histochemical profile. In addition, biopsies of 20 consecutive patients who did not take OsmoPrep and who underwent concurrent endoscopy and colonoscopy were reviewed, and no deposits with similar histochemical profile were identified. In summary, we have characterized a unique form of gastritis associated with OsmoPrep use. Attention to clinical history and use of a select panel of histochemical stains allow for accurate diagnosis.

  16. Tech Prep: Building a Framework for Future Research, Evaluation, and Program Practice. Focus Group Report.

    ERIC Educational Resources Information Center

    Elliott, Barbara G.

    This document reports on three focus groups comprised of state officials, local practitioners and supporters, and researchers who were convened to provide input on strategies for assessing and validating the effects of tech prep. Part I provides a brief summary of the groups' discussions, including major points and broad themes in these four topic…

  17. A Culture of High Expectations: Teacher Leadership at Pritzker College Prep

    ERIC Educational Resources Information Center

    Aspen Institute, 2014

    2014-01-01

    Relying on teachers as culture leaders is a solution embraced by many high-performing charter schools. This profile focuses on the design of the Grade Level Lead roles at Pritzker College Prep, a member of the Noble Network of Schools in Chicago. The successes of this school and network are well-documented: Of non-selective public high schools in…

  18. Parkland College-Champaign/Ford Vocational System Tech Prep Final Report.

    ERIC Educational Resources Information Center

    Parkland Coll., Champaign, IL.

    An industrial/technical tech prep pilot project that involved students from three secondary schools in Urbana-Champaign, Illinois, was implemented in Fall 1991. Highlights of the implementation phase included an informational/orientation meeting for parents, delivery of four courses, and field trips to local manufacturing firms for the tech prep…

  19. High Schools that Work and Tech Prep: Improving Student Performance in Basic Skills.

    ERIC Educational Resources Information Center

    Flowers, Jim

    2000-01-01

    Test results for 244 agricultural education students in High Schools that Work (HSTW) sites in North Carolina indicated that, compared to all students at HSTW sites and to college-prep students, they failed to meet HSTW goals in math, reading, and science but were making progress. Their math and science performance was higher than other vocational…

  20. Tech Prep Implementation. Self-Assessment Inventory. Middle/High School Level. Postsecondary Level.

    ERIC Educational Resources Information Center

    Partnership for Academic and Career Education, Pendleton, SC.

    These two self-assessment inventories are designed to be used for evaluation of tech prep implementation at the middle/high school and postsecondary levels. The middle/high school version is intended to be completed by the district/school, the postsecondary form by the technical college. The form provides for rating the level of implementation as…

  1. Restructuring Student Experiences Using Tech Prep Mapping To Integrate Vocational and Academic Curriculum.

    ERIC Educational Resources Information Center

    Pirozzoli, Don

    The growing emphasis on accountability and the demand for better prepared students is pressing institutions of higher education to examine restructuring. Student experiences represent an important arena for school restructuring, and a useful approach to changing student experiences is the Tech Prep Mapping (TPM) process. The TPM process requires…

  2. A Case Study of Interagency Collaboration as Reported by the PREP Advisory Committee

    ERIC Educational Resources Information Center

    Greene, Cathleen M.

    2010-01-01

    The purpose of this study was to explore with key members of the Pilot Reintegration Education Program (PREP) Advisory Committee, the characteristics of their interagency process and how they perceived that these factors contributed to accomplishing the common objective of providing a smooth and effective transition for students between release…

  3. Relationship of Tech Prep and Dual Credit to College Readiness and Retention

    ERIC Educational Resources Information Center

    Kim, JoHyun

    2014-01-01

    This study examined the relationship of tech prep and dual credit to college readiness in reading, writing, and math and retention, measured as total college-level credit hours earned. A sample of 612 high school graduates who enrolled in a community college in two consortia, one in Florida (n = 339) and the other in Oregon…

  4. Moving beyond Test-Prep Pedagogy: Dialoguing with Multicultural Preservice Teachers for a Quality Education

    ERIC Educational Resources Information Center

    Rodríguez, Louie F.

    2013-01-01

    In a "post-NCLB era," the schooling experiences of mostly low-income students of color continue to be consumed by a test-prep pedagogy--narrowed curriculum, low expectations, and ignored relationships. In this article the author describes a pedagogical approach using educational dialogues to engage preservice teachers to critically…

  5. The DELTA PREP Initiative" Accelerating Coalition Capacity for Intimate Partner Violence Prevention

    ERIC Educational Resources Information Center

    Zakocs, Ronda; Freire, Kimberley E.

    2015-01-01

    Background: The DELTA PREP Project aimed to build the prevention capacity of 19 state domestic violence coalitions by offering eight supports designed to promote prevention integration over a 3-year period: modest grant awards, training events, technical assistance, action planning, coaching hubs, the Coalition Prevention Capacity Assessment, an…

  6. Tech Prep. South Dakota Career Activities for the Classroom, 4th Edition, 1998-1999.

    ERIC Educational Resources Information Center

    Kucker, Marsha, Comp.

    This document presents a sampling of projects and activities that have been implemented in Tech Prep training in South Dakota, or will be implemented during the upcoming school year. The projects and activities are categorized into 12 areas: career clusters; career units and activities; curriculum materials; employability skills; entrepreneurship;…

  7. A Case Study of Interagency Collaboration as Reported by the PREP Advisory Committee

    ERIC Educational Resources Information Center

    Greene, Cathleen M.

    2010-01-01

    The purpose of this study was to explore with key members of the Pilot Reintegration Education Program (PREP) Advisory Committee, the characteristics of their interagency process and how they perceived that these factors contributed to accomplishing the common objective of providing a smooth and effective transition for students between release…

  8. Appendix C: Background and Methodology for Alternative Certification Pilot. [2014 Teacher Prep Review

    ERIC Educational Resources Information Center

    Greenberg, Julie; Walsh, Kate; McKee, Arthur

    2014-01-01

    The "NCTQ Teacher Prep Review" evaluates the quality of programs that provide preservice preparation of public school teachers. As part of the "Review," this appendix reports on a pilot study of new standards for assessing the quality of alternative certification programs. Background and methodology for alternative…

  9. Tech-Prep in New York State: Profiles of Four Diverse Programs.

    ERIC Educational Resources Information Center

    Frenkel, Michael W.; Brodsky, Stanley M.

    These case studies highlight the diversity of four tech programs that responded with a unique set of organizational policies and procedures to a unique set of challenges. The case study on City Tech Tech-Prep Consortium in Brooklyn focuses on three strategies: transition to City Tech program, postsecondary component, and program evaluation. The…

  10. The DELTA PREP Initiative" Accelerating Coalition Capacity for Intimate Partner Violence Prevention

    ERIC Educational Resources Information Center

    Zakocs, Ronda; Freire, Kimberley E.

    2015-01-01

    Background: The DELTA PREP Project aimed to build the prevention capacity of 19 state domestic violence coalitions by offering eight supports designed to promote prevention integration over a 3-year period: modest grant awards, training events, technical assistance, action planning, coaching hubs, the Coalition Prevention Capacity Assessment, an…

  11. Development and Validation of the Experiential Learning Survey

    ERIC Educational Resources Information Center

    Clem, Jamie M.; Mennicke, Annelise M.; Beasley, Christina

    2014-01-01

    Experiential learning is recommended as a way to increase critical thinking and engagement, enhance theory-informed practice, increase preparedness, and improve multicultural understanding for students involved in social work education. The purpose of this study is to validate the Experiential Learning Survey (ELS), which measures students'…

  12. Development of the Reasonable Accommodation Factor Survey: Results and Implications

    ERIC Educational Resources Information Center

    Dong, Shengli; MacDonald-Wilson, Kim L.; Fabian, Ellen

    2010-01-01

    The purpose of this study was (a) to explore the latent factors in the "Reasonable Accommodation Factor Survey" (RAFS) instrument and (b) to compare scores on the latent factors of the RAFS by participant's role. Eight latent factors were identified through an exploratory factor analysis with orthogonal rotation. The reliability tests…

  13. Development and Validation of the Experiential Learning Survey

    ERIC Educational Resources Information Center

    Clem, Jamie M.; Mennicke, Annelise M.; Beasley, Christina

    2014-01-01

    Experiential learning is recommended as a way to increase critical thinking and engagement, enhance theory-informed practice, increase preparedness, and improve multicultural understanding for students involved in social work education. The purpose of this study is to validate the Experiential Learning Survey (ELS), which measures students'…

  14. Development of the Reasonable Accommodation Factor Survey: Results and Implications

    ERIC Educational Resources Information Center

    Dong, Shengli; MacDonald-Wilson, Kim L.; Fabian, Ellen

    2010-01-01

    The purpose of this study was (a) to explore the latent factors in the "Reasonable Accommodation Factor Survey" (RAFS) instrument and (b) to compare scores on the latent factors of the RAFS by participant's role. Eight latent factors were identified through an exploratory factor analysis with orthogonal rotation. The reliability tests…

  15. Developing Melodic Dictation Pedagogy: A Survey of College Theory Instructors

    ERIC Educational Resources Information Center

    Paney, Andrew S.; Buonviri, Nathan O.

    2017-01-01

    The purpose of this study was to identify pedagogical approaches to melodic dictation used by college music theory instructors at National Association of Schools of Music accredited institutions. Instructors (N = 270) from 45 states responded to an online survey targeting melodic dictation instruction in their freshman theory courses. Results…

  16. Developing a Survey for Assessing Preferences in Constructivist Context-Aware Ubiquitous Learning Environments

    ERIC Educational Resources Information Center

    Tsai, P.-S.; Tsai, C.-C.; Hwang, G.-J.

    2012-01-01

    This study developed a survey to explore students' preferences in constructivist context-aware ubiquitous learning environments. A constructivist context-aware ubiquitous learning (u-learning) environment survey (CULES) was developed, consisting of eight scales, including ease of use, continuity, relevance, adaptive content, multiple sources,…

  17. Library Surveys and Development Plans, An Annotated Bibliography. Bibliography Series, Number 3.

    ERIC Educational Resources Information Center

    ERIC Clearinghouse on Library and Information Sciences, Minneapolis, Minn.

    This annotated bibliography of 104 library surveys and development plans at the state or national level published since 1965 is based on the collection of the ERIC Clearinghouse for Library and Information Sciences. It includes most of the post-1965 titles listed in Galen E. Rike's "Statewide Library Surveys and Development Plans, An Annotated…

  18. The Use of Online Surveys to Measure Satisfaction in Job Training and Workforce Development

    ERIC Educational Resources Information Center

    Schmidt, Steve; Strachota, Elaine; Conceicao, Simone

    2006-01-01

    This paper examines two empirical studies that used online surveys to collect data to measure satisfaction in job training and workforce development. A description of each study, findings related to response rate, the processes used in online survey development and implementation, as well as recommendations for the future use of online surveys…

  19. Exploring Career Options and Possibilities Later in Life: Adult (Age 50-75) Career Development Survey

    ERIC Educational Resources Information Center

    Smith, Angela Carmella

    2009-01-01

    A survey instrument was developed entitled the "Adult (age 50-75) Career Development Survey" (ACDS) to provide an empirical foundation for understanding the current needs of individuals age 50-75 and learning about their attitudes toward, willingness to, and experience in using career counseling and technology in making decisions on…

  20. PrEP for Africa: What we have learnt and what is needed to move to program implementation

    PubMed Central

    Mugo, Nelly R; Ngure, Kenneth; Kiragu, Michael; Irungu, Elizabeth; Kilonzo, Nduku

    2016-01-01

    Purpose An investment in PrEP delivery must have public health impact in reducing HIV infections. Sustainable delivery of PrEP requires policy, integration of services and synergy with other existing HIV prevention programs. This review discusses key policy and programmatic considerations for implementation and scale up of PrEP in Africa. Recent Findings PrEP delivery has been delayed by concerns about adherence and delivery in ‘real world’ settings. Demonstration projects and clinical service delivery models are providing evidence of PrEP effectiveness with an impact much higher than that found in randomized clinical trials. Data confirm that PrEP uptake, adherence and retention has been high, more so by persons who perceive themselves at high risk for HIV infection, and PrEP is well tolerated. PrEP delivery is more than dispensation of a pill and programs should address other risk drivers, which differ by population. In Africa, barriers to PrEP uptake and adherence include stigma among MSM and low HIV risk perception among young women. Additional data have provided insight into optimal points of service delivery, provider training requirements and quality assurance needs. Of the 2 million new HIV infections in 2014, 70% were in Africa. PrEP use is not lifelong and use limited to periods of risk may be both effective and cost-effective for the continent. Summary HIV prevention programs should determine strategies to identify those at substantial risk for HIV infection, formulate and deliver PrEP in combination with interventions that target social drivers of HIV vulnerability specific to each population. Policy guidance for optimal combination of interventions and service delivery avenues, clinical protocols, health infrastructure requirements are required. Cost-effectiveness and efficiency data are essential for policy guidance to navigate ethical questions over use of antiretroviral therapy for HIV negative individuals when treatment coverage has not been

  1. State of the art survey of network operating systems development

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The results of the State-of-the-Art Survey of Network Operating Systems (NOS) performed for Goddard Space Flight Center are presented. NOS functional characteristics are presented in terms of user communication data migration, job migration, network control, and common functional categories. Products (current or future) as well as research and prototyping efforts are summarized. The NOS products which are revelant to the space station and its activities are evaluated.

  2. Preferences and Priorities for Professional Development in the Security Workforce: A Report of the Professional Development Survey

    DTIC Science & Technology

    2004-01-01

    The Professional Development Survey was designed by the Defense Personnel Security Research Center (PERSEREC) to assess the state of the security...profession and to learn about practitioner views of the adequacy of professional training and need for professional development programs. This report is...workforce: military departments, Defense agencies, intelligence community agencies, and non-DoD agencies. The Professional Development Survey reflects the

  3. Developing a survey to assess factors that contribute to physician involvement in clinical research.

    PubMed

    Taliercio, Vanina; Logan, Judith R; Kalpathy-Cramer, Jayashree; Oteroa, Paula

    2013-01-01

    Investment in research, including clinical research, has positive effects both on health of a population and economic growth of a country. Several factors have been suggested as being related to the performance of clinical research. The goal of this work was to develop and perform initial validation of a survey that measures both current research involvement of physicians, as well as previously noted factors and additional informatics factors affecting this involvement. The survey was developed in both English and Spanish with the goal of its use in Latin America. The initial survey was developed primarily from experience with other validated surveys developed for similar purposes. It was validated in three stages with modification or elimination of questions as indicated by this testing. The final survey contains 33 questions in the categories of research experience, education in research, environmental factors, computer experience, and collaboration.

  4. Professional Development Needs of Science and Technology Librarians: Results of the 2012 SLA/PAM Professional Development Committee Survey

    ERIC Educational Resources Information Center

    Tchangalova, Nedelina; Lam, Margaret N.

    2013-01-01

    This article reports and analyzes the survey results on the continuing education needs of librarians with current job responsibilities in the science, technology, and engineering subject fields. The intended purpose of the survey results is to assist conference coordinators in the development of a continuing education program at future Special…

  5. Trends in Food Research and Development: A Survey of the Commercial Food Industry

    DTIC Science & Technology

    1987-09-01

    panies. The survey response rate of 68% compared favorably with another survey of many of the same companies by Food Processing Magazine , which...Security Classification) TRENDS IN FOOD RESEARCH AND DEVELOPMENT: A SURVEY OF THE COMMERICAL FOOD INDUSTRY 12. PERSONAL AUTHOR(S) STEPHEN A. REI 13a...SUPPLEMENTARY NOTATION 17. COSATI CODES 16. SUBJECT TERMS (Continue on reverse if necessary and identify by block number) FIELD GROUP SUB-GROUP RATIONS FOOD

  6. Development of a National Occupational Exposure Survey and Database associated with NIOSH hazard surveillance initiatives.

    PubMed

    Boiano, J M; Hull, R D

    2001-02-01

    NIOSH pioneered hazard surveillance in the workplace by designing and conducting the 1972 to 1974 National Occupational Hazard Survey (NOHS), the 1981 to 1983 National Occupational Exposure Survey (NOES), and the 1984 to 1989 National Occupational Health Survey of Mining (NOHSM). The databases developed from these three on-site surveys represent unique resources for associating potential chemical, physical and biological agents with industries and occupational groups. The data have been a primary source of information for NIOSH, regulatory agencies, health professionals, researchers, and labor organizations in establishing priorities for prevention strategies that include medical and engineering interventions, development of occupational standards, and the identification of research needs. Recognizing that the data from these surveys are becoming dated, a multidisciplinary team comprising members from various NIOSH research divisions was established to develop a hazard surveillance strategy for the Institute, including options for a national hazard surveillance survey and database. The proposed new hazard survey builds on lessons learned from the previous surveys, seeks opportunities to incorporate existing data from other sources, expands the scope of industries and hazards, and takes advantage of advances in data gathering, processing and dissemination technology. This article presents current considerations and recommendations for a new hazard survey and database.

  7. Success Is in the Details. No Element of Tech Prep Escapes the Fine-Tuned Planning of Oregon's Design Teams.

    ERIC Educational Resources Information Center

    Buhl, Cheryl L.; And Others

    1995-01-01

    Articles describe elements of Oregon's' tech prep program: "New Software Helps Students Visualize a Career Path" (Buhl); "Bridge Construction Ahead" (Roach); and "To Track Students, Oregon Goes to the Bar" (Dutson). (JOW)

  8. Commentary: the value of PrEP for people who inject drugs

    PubMed Central

    Coleman, Rosalind L; McLean, Susie

    2016-01-01

    Introduction The offer of pre-exposure prophylaxis (PrEP) is recommended as an additional option for HIV prevention for people at substantial risk of HIV infection as part of combination HIV prevention approaches. Implementing this depends on integrating PrEP in public health programmes that address risky practices with evidence-based interventions, and that operate in an enabling legal and policy environment for the delivery of health services to those at higher risk of HIV infection. What does this recommendation mean in terms of the diverse range of HIV prevention needs of key populations, some of whom are so discriminated against that they exist essentially outside formal systems such as national public health services, and for whom a substantial risk of HIV is part of a larger adverse and hostile situation? We discuss this question with reference to people who inject drugs, informed by concerns and comments that emerged from a series of consultations. Discussion HIV prevention is part of a spectrum of injecting drug users’ priorities, and their access and uptake of HIV prevention services is contingent on their wider “risk environment.” The need to address structural barriers to services and human rights violations, and to improve access to comprehensive harm reduction programmes are of prime importance and would have higher value than a mono-focus on HIV prevention. Where existing harm reduction activities are inadequate, fragile or dependent on external donors, shifts in funding priorities, including, for example, towards PrEP, could threaten investment in the broader programmes. For these reasons, it cannot be assumed that PrEP promotion will always be supported by people who inject drugs. The sexual partners of people who inject drugs, non-opioid users who also inject and for whom there is no established substitution treatment, as well as drug users who are unable to negotiate safe sex may value PrEP. As for all key populations, the involvement of

  9. Tailored combination prevention packages and PrEP for young key populations

    PubMed Central

    Pettifor, Audrey; Nguyen, Nadia L; Celum, Connie; Cowan, Frances M; Go, Vivian; Hightow-Weidman, Lisa

    2015-01-01

    Introduction Young key populations, defined in this article as men who have sex with men, transgender persons, people who sell sex and people who inject drugs, are at particularly high risk for HIV. Due to the often marginalized and sometimes criminalized status of young people who identify as members of key populations, there is a need for HIV prevention packages that account for the unique and challenging circumstances they face. Pre-exposure prophylaxis (PrEP) is likely to become an important element of combination prevention for many young key populations. Objective In this paper, we discuss important challenges to HIV prevention among young key populations, identify key components of a tailored combination prevention package for this population and examine the role of PrEP in these prevention packages. Methods We conducted a comprehensive review of the evidence to date on prevention strategies, challenges to prevention and combination prevention packages for young key populations. We focused specifically on the role of PrEP in these prevention packages and on young people under the age of 24, and 18 in particular. Results and discussion Combination prevention packages that include effective, acceptable and scalable behavioural, structural and biologic interventions are needed for all key populations to prevent new HIV infections. Interventions in these packages should meaningfully involve beneficiaries in the design and implementation of the intervention, and take into account the context in which the intervention is being delivered to thoughtfully address issues of stigma and discrimination. These interventions will likely be most effective if implemented in conjunction with strategies to facilitate an enabling environment, including increasing access to HIV testing and health services for PrEP and other prevention strategies, decriminalizing key populations’ practices, increasing access to prevention and care, reducing stigma and discrimination, and

  10. Commentary: the value of PrEP for people who inject drugs.

    PubMed

    Coleman, Rosalind L; McLean, Susie

    2016-01-01

    The offer of pre-exposure prophylaxis (PrEP) is recommended as an additional option for HIV prevention for people at substantial risk of HIV infection as part of combination HIV prevention approaches. Implementing this depends on integrating PrEP in public health programmes that address risky practices with evidence-based interventions, and that operate in an enabling legal and policy environment for the delivery of health services to those at higher risk of HIV infection. What does this recommendation mean in terms of the diverse range of HIV prevention needs of key populations, some of whom are so discriminated against that they exist essentially outside formal systems such as national public health services, and for whom a substantial risk of HIV is part of a larger adverse and hostile situation? We discuss this question with reference to people who inject drugs, informed by concerns and comments that emerged from a series of consultations. HIV prevention is part of a spectrum of injecting drug users' priorities, and their access and uptake of HIV prevention services is contingent on their wider "risk environment." The need to address structural barriers to services and human rights violations, and to improve access to comprehensive harm reduction programmes are of prime importance and would have higher value than a mono-focus on HIV prevention. Where existing harm reduction activities are inadequate, fragile or dependent on external donors, shifts in funding priorities, including, for example, towards PrEP, could threaten investment in the broader programmes. For these reasons, it cannot be assumed that PrEP promotion will always be supported by people who inject drugs.The sexual partners of people who inject drugs, non-opioid users who also inject and for whom there is no established substitution treatment, as well as drug users who are unable to negotiate safe sex may value PrEP. As for all key populations, the involvement of people who inject drugs in

  11. "Support Your Client at the Space That They're in": HIV Pre-Exposure Prophylaxis (PrEP) Prescribers' Perspectives on PrEP-Related Risk Compensation.

    PubMed

    Calabrese, Sarah K; Magnus, Manya; Mayer, Kenneth H; Krakower, Douglas S; Eldahan, Adam I; Hawkins, Lauren A Gaston; Underhill, Kristen; Hansen, Nathan B; Kershaw, Trace S; Betancourt, Joseph R; Dovidio, John F

    2017-04-01

    Despite the demonstrated effectiveness of HIV pre-exposure prophylaxis (PrEP) and evidence that most PrEP users do not engage in risk compensation (i.e., increased risk behavior due to a perceived decrease in HIV susceptibility), some healthcare providers report patient risk compensation to be a deterrent to prescribing PrEP. Overcoming this barrier is essential to supporting PrEP access and uptake among people at risk for HIV. To inform such efforts, this qualitative study explored PrEP-related risk compensation attitudes among providers with firsthand experience prescribing PrEP. US-based PrEP providers (n = 18), most of whom were HIV specialists, were recruited through direct outreach and referral from colleagues and other participants. Individual 90-min semistructured interviews were conducted by phone or in person from September 2014 through February 2015, transcribed, and thematically analyzed. Three attitudinal themes emerged: (1) providers' role is to support patients in making informed decisions, (2) risk behavior while taking PrEP does not fully offset PrEP's protective benefit (i.e., PrEP confers net protection, even with added behavioral risk), and (3) PrEP-related risk compensation is unduly stigmatized within and beyond the healthcare community. Participants were critical of other healthcare providers' negative judgment of patients and reluctance to prescribe PrEP due to anticipated risk compensation. Several providers also acknowledged an evolution in their thinking from initial ambivalence toward greater acceptance of PrEP and PrEP-related behavior change. PrEP providers' insights about risk compensation may help to address unsubstantiated concerns about PrEP-related risk compensation and challenge the acceptability of withholding PrEP on these grounds.

  12. The Trojan Lifetime Champions Health Survey: Development, Validity, and Reliability

    PubMed Central

    Sorenson, Shawn C.; Romano, Russell; Scholefield, Robin M.; Schroeder, E. Todd; Azen, Stanley P.; Salem, George J.

    2015-01-01

    Context Self-report questionnaires are an important method of evaluating lifespan health, exercise, and health-related quality of life (HRQL) outcomes among elite, competitive athletes. Few instruments, however, have undergone formal characterization of their psychometric properties within this population. Objective To evaluate the validity and reliability of a novel health and exercise questionnaire, the Trojan Lifetime Champions (TLC) Health Survey. Design Descriptive laboratory study. Setting A large National Collegiate Athletic Association Division I university. Patients or Other Participants A total of 63 university alumni (age range, 24 to 84 years), including former varsity collegiate athletes and a control group of nonathletes. Intervention(s) Participants completed the TLC Health Survey twice at a mean interval of 23 days with randomization to the paper or electronic version of the instrument. Main Outcome Measure(s) Content validity, feasibility of administration, test-retest reliability, parallel-form reliability between paper and electronic forms, and estimates of systematic and typical error versus differences of clinical interest were assessed across a broad range of health, exercise, and HRQL measures. Results Correlation coefficients, including intraclass correlation coefficients (ICCs) for continuous variables and κ agreement statistics for ordinal variables, for test-retest reliability averaged 0.86, 0.90, 0.80, and 0.74 for HRQL, lifetime health, recent health, and exercise variables, respectively. Correlation coefficients, again ICCs and κ, for parallel-form reliability (ie, equivalence) between paper and electronic versions averaged 0.90, 0.85, 0.85, and 0.81 for HRQL, lifetime health, recent health, and exercise variables, respectively. Typical measurement error was less than the a priori thresholds of clinical interest, and we found minimal evidence of systematic test-retest error. We found strong evidence of content validity, convergent

  13. Adolescent lifestyle and behaviour: a survey from a developing country.

    PubMed

    Qidwai, Waris; Ishaque, Sidra; Shah, Sabeen; Rahim, Maheen

    2010-09-27

    Adolescents form two-thirds of our population. This is a unique group of people with special needs. Our survey aims to identify the lifestyle and behavioral patterns in this group of people and subsequently come up with issues that warrant special attention. A survey was performed in various schools of Karachi. Data collection was done via a face-to-face interview based on a structured, pre-tested questionnaire. Participants included all willing persons between 12-19 years of age. Most adolescents with lifestyle issues fell in the age group of 16-18 years. Females were more depressed than males and had more sleep problems. Substance abuse and other addictions were documented more in males. Watching television or listening to music was stated as the most common late night activity (61.8%) and therefore was also referred to as the contributory factor for less than eight hours of sleep each day. (58.9%) of the respondents are getting less than eight hours of sleep daily. (41.5%) of the respondents who felt depressed sought treatment for it. Quite a few of them were also indulged in substance abuse and other addictions. Only (16.8%) of the respondents opined that physical activity is essential for health. Thirty-five adolescents out of all the respondents were smoking cigarettes currently, whereas 7% of the respondents chewed paan (areca nut). Peer pressure was the most common reason (37.1%) to start smoking. Adolescents need to be treated as a distinct segment of our population and it is important to realize and address their health and lifestyle problems. Inadequate sleep, depression and smoking were the leading unhealthy behaviours among the respondents. Families can play an important role to help these adolescents live a healthier life. Further research studies should be carried out to highlight issues of concern and their possible solutions in this population.

  14. Development, Implementation, and Analysis of a National Survey of Faculty Goals for Undergraduate Chemistry Laboratory

    ERIC Educational Resources Information Center

    Bruck, Aaron D.; Towns, Marcy

    2013-01-01

    This work reports the development of a survey for laboratory goals in undergraduate chemistry, the analysis of reliable and valid data collected from a national survey of college chemistry faculty, and a synthesis of the findings. The study used a sequential exploratory mixed-methods design. Faculty goals for laboratory emerged across seven…

  15. A Survey of Hardware and Software Technologies for the Rapid Development of Multimedia Instructional Modules

    ERIC Educational Resources Information Center

    Ganesan, Nanda

    2008-01-01

    A survey of hardware and software technologies was conducted to identify suitable technologies for the development of instructional modules representing various instructional approaches. The approaches modeled were short PowerPoint presentations, chalk-and-talk type of lectures and software tutorials. The survey focused on identifying application…

  16. Development, Implementation, and Analysis of a National Survey of Faculty Goals for Undergraduate Chemistry Laboratory

    ERIC Educational Resources Information Center

    Bruck, Aaron D.; Towns, Marcy

    2013-01-01

    This work reports the development of a survey for laboratory goals in undergraduate chemistry, the analysis of reliable and valid data collected from a national survey of college chemistry faculty, and a synthesis of the findings. The study used a sequential exploratory mixed-methods design. Faculty goals for laboratory emerged across seven…

  17. The Development and Preliminary Validation of the Behavior, Environment, and Changeability Survey (BECS)

    ERIC Educational Resources Information Center

    Walsh, Jennifer R.; Hebert, Angel; Byrd-Bredbenner, Carol; Carey, Gale; Colby, Sarah; Brown-Esters, Onikia N.; Greene, Geoffrey; Hoerr, Sharon; Horacek, Tanya; Kattelmann, Kendra; Kidd, Tandalayo; Koenings, Mallory; Phillips, Beatrice; Shelnutt, Karla P.; White, Adrienne A.

    2012-01-01

    Objective: To develop and test the validity of the Behavior, Environment, and Changeability Survey (BECS) for identifying the importance and changeability of nutrition, exercise, and stress management behavior and related aspects of the environment. Design: A cross-sectional, online survey of the BECS and selected validated instruments. Setting:…

  18. The Development and Preliminary Validation of the Behavior, Environment, and Changeability Survey (BECS)

    ERIC Educational Resources Information Center

    Walsh, Jennifer R.; Hebert, Angel; Byrd-Bredbenner, Carol; Carey, Gale; Colby, Sarah; Brown-Esters, Onikia N.; Greene, Geoffrey; Hoerr, Sharon; Horacek, Tanya; Kattelmann, Kendra; Kidd, Tandalayo; Koenings, Mallory; Phillips, Beatrice; Shelnutt, Karla P.; White, Adrienne A.

    2012-01-01

    Objective: To develop and test the validity of the Behavior, Environment, and Changeability Survey (BECS) for identifying the importance and changeability of nutrition, exercise, and stress management behavior and related aspects of the environment. Design: A cross-sectional, online survey of the BECS and selected validated instruments. Setting:…

  19. Construction and Analysis of Organization Climate Surveys. Training and Development Research Center Project No. 26.

    ERIC Educational Resources Information Center

    McLean, Gary N.

    Climate surveys are an important diagnostic tool in organization development. The purposes of this paper are to: (1) present the advantages and disadvantages of using a survey as a diagnostic tool, as compared to interviewing, observation, and the use of secondary (preexisting and non-intrusive) information; (2) argue for customized climate…

  20. Development of the Persistence in Engineering (PIE) Survey Instrument. Research Brief

    ERIC Educational Resources Information Center

    Eris, Ozgur; Chen, Helen; Bailey, Tori; Engerman, Kimarie; Loshbaugh, Heidi; Griffin, Ashley; Lichtenstein, Gary; Cole, Angela

    2007-01-01

    The Persistence In Engineering (PIE) survey was developed to identify and characterize the fundamental factors that influence students' intentions to pursue an engineering degree over the course of their undergraduate career, and upon graduation, to practice engineering as a profession. The PIE survey is one of five data-gathering methods used in…

  1. A Survey of Hardware and Software Technologies for the Rapid Development of Multimedia Instructional Modules

    ERIC Educational Resources Information Center

    Ganesan, Nanda

    2008-01-01

    A survey of hardware and software technologies was conducted to identify suitable technologies for the development of instructional modules representing various instructional approaches. The approaches modeled were short PowerPoint presentations, chalk-and-talk type of lectures and software tutorials. The survey focused on identifying application…

  2. Results of a Follow-Up Survey of CAI Development in Selected Institutions of Higher Education.

    ERIC Educational Resources Information Center

    Karrer, Urs

    Designed to test the premise that the production system for courseware has a strong impact on the quality of the courseware developed, a survey of 14 U.S. institutions of higher education was conducted in 1986 to investigate the production systems used by these schools. Many of the questions used and the list of institutions surveyed were…

  3. Results of a Follow-Up Survey of CAI Development in Selected Institutions of Higher Education.

    ERIC Educational Resources Information Center

    Karrer, Urs

    Designed to test the premise that the production system for courseware has a strong impact on the quality of the courseware developed, a survey of 14 U.S. institutions of higher education was conducted in 1986 to investigate the production systems used by these schools. Many of the questions used and the list of institutions surveyed were…

  4. Survey of Postdoctorates at FFRDCs: Final Report [Federally Funded Research and Development Centers

    SciTech Connect

    Mulrow, Jeri

    2010-06-30

    The 2009 FFRDC survey collected the total number of postdocs employed by FFRDCs in the United States—categorized by source of support, citizenship, sex, and field of research—as of October 1, 2009. The universe for the 2009 GSS-FFRDC survey was the Master Government List of Federally Funded Research and Development Centers. The 2009 survey also contacted the NIH’s Intramural Research Program because it employs the largest number of postdocs in the federal government. The FFRDC survey collected data via a web instrument. Topics included the type of support the postdocs received (federal and nonfederal), their sex, citizenship, race/ethnicity, and field of research.

  5. Developing Survey Research Infrastructure At An Historically Black College/University To Address Health Disparities

    PubMed Central

    Howard, Daniel L.; Boyd, Carlton L.; Kalsbeek, Bill; Godley, Paul A.

    2011-01-01

    This article describes the development of the Center for Survey Research at Shaw University, a Historically Black College and University (HBCU), and its efforts to build a data collection infrastructure that addresses issues germane to health disparities research in the African American population. Academic institutions that are similar to Shaw in size, mission, and background can use the Project EXPORT collaboration and the Center for Survey Research as models for establishing their own research infrastructure and subsequent survey center in order to address health disparities through the use of survey methodology. PMID:22090795

  6. Report on the Development and Evaluation of the "Survey of Undergraduate Alumni" and the "Survey of Graduate Alumni" in Health Education at San Francisco State University.

    ERIC Educational Resources Information Center

    Yee, Darlene

    The "Survey of Undergraduate Alumni" and the "Survey of Graduate Alumni" for the Department of Health Education at San Francisco State University (California) were developed and evaluated. The surveys were intended to measure alumni satisfaction with the programs in health education. Using a modified Delphi technique, a group…

  7. Characterization of synthetic macroporous ion-exchange resins in low-pressure cartridges and columns. Evaluation of the performance of Macro-Prep 50 S resin in the purification of anti-Klenow antibodies from goat serum.

    PubMed

    Dunn, L; Abouelezz, M; Cummings, L; Navvab, M; Ordunez, C; Siebert, C J; Talmadge, K W

    1991-07-12

    Three ion-exchange materials and one hydrophobic-interaction chromatography packing, based on a rigid macroporous polymer with large, relatively uniform pores, have been evaluated for low-pressure liquid chromatography of antibodies. These sorbents have high capacities for both small and large proteins and are mechanically, chemically, and thermally stable. Macro-Prep 50 S. CM and Q ion-exchange materials are strongly acidic, weakly acidic, and strongly basic, respectively. Protein binding and recovery, pressure-flow properties, and chemical and thermal stability were determined for each sorbent. A rapid, two-step method for the purification of anti-Klenow antibodies from goat serum was developed, based on the Macro-Prep 50 S strong-acid cation-exchange material and the Econo-Pac HIC prepacked hydrophobic-interaction cartridge.

  8. Survey Reflects Student Development at D-Q University.

    ERIC Educational Resources Information Center

    Machamer, Ann Marie

    1999-01-01

    Describes a study that compared student development at Deganawidah-Quetzalcoatl University (D-Q U) in California with that at non-tribal institutions. Results indicated higher levels of student satisfaction at D-Q U, lower levels of learning and personal development, somewhat lower rates of degree completion, and similar transfer rates. Recommends…

  9. Black Bear Prep plant replaces high-frequency screens with fine wire sieves

    SciTech Connect

    Barbee, C.J.; Nottingham, J.

    2007-12-15

    At the Black Bear prep plant (near Wharncliffe, WV, USA) the clean coal from the spirals traditionally reported to high-frequency screens, which removed high-ash clay fines. Screens have inherent inefficiencies that allow clean coal to report to the screen underflow. The goal of this project was to capture the maximum amount of spiral clean coal while still removing the high-ash clay material found in the spiral product. The reduction of the circulating load and plant downtime for unscheduled maintenance were projected as additional benefits. After the plant upgrade, the maintenance related to the high frequency screens was eliminated and an additional 2.27 tons per hour (tph) of fine coal was recovered, which resulted in a payback period of less than one year. The article was adapted from a paper presented at Coal Prep 2007 in April 2007, Lexington, KY, USA. 1 ref., 1 fig., 1 tab.

  10. PREPARATIVE ISOLATION AND PURIFICATION OF CHEMICAL CONSTITUENTS OF BELAMCANDA BY MPLC, HSCCC AND PREP-HPLC

    PubMed Central

    Wang, Xiaohong; Liang, Yong; Peng, Cuilin; Xie, Huichun; Pan, Man; Zhang, Tianyou; Ito, Yoichiro

    2010-01-01

    Combined with medium-pressure liquid chromatography (MPLC) and preparative high-pressure liquid chromatography (Prep-HPLC), high-speed countercurrent chromatography (HSCCC) was successfully applied for separation and purification of isoflavonoids from the extract of belamcanda. HSCCC separation was performed on a two-phase solvent system composed of methyl tert-butyl ether -ethyl acetate - n-butyl alcohol – acetonitrile −0.1% aqueous trifluoroacetic acid at a volume radio of 1:2:1:1:5. Semi-purified peak fractions from HSCCC separation were further purified by Prep-HPLC. Nine well-separated fractions were analyzed by HPLC-UV absorption spectrometry to determine their purities and characterized with ESI-MSn. Except for peaksland VII (unknown) seven compounds were identified as apocynin (peak II), mangiferin (peak III), 7-O-methylmangiferin (peak IV), hispidulin (peak V), 3′-hydroxyltectoridin (peak VI), iristectorin B (peak VII), isoiridin (peak IX). PMID:21552369

  11. Surveys on sexual health: recent developments and future directions

    PubMed Central

    Wellings, K.; Cleland, J.

    2001-01-01

    The increasingly widespread adoption of the term sexual health reflects a move away from the medicalisation of this specialty. The focus has shifted from clinical practice to lifestyle and behaviour; from clinician to client, and from treatment to prevention. This article discusses these themes, identifying their implications for sexual health research. Recent times have seen, for example, a growing number of studies combining biological and behavioural measures conducted by interdisciplinary teams able to combine biomedical measurements of morbidity with insights into the subjective interpretations of symptoms and consequences. Considerable progress has been made, too, in mounting community based studies, and much has been achieved in gaining compliance and refining sampling methods. Integrated sexual health services, encompassing more than contraceptive or prophylactic service provision, have provided the impetus to investigation of the costs and benefits of coordinated family planning and genitourinary medicine services. Despite its broader focus, there remain opportunities for sexual health research to expand its remit. Studies to date may have focused too narrowly on pathological, to the neglect of health enhancing, consequences of sexual behaviour. Key Words: surveys; sexual health PMID:11463921

  12. Swords, Shields, and the Fight for Our Children: Lessons from Urban Prep

    ERIC Educational Resources Information Center

    King, Tim

    2011-01-01

    The grim statistics are well known, but bear repeating: in Chicago, close to 60% of Black boys do not graduate from high school, and only one in forty receive a bachelor's degree by age 25. In the fall of 2006, Urban Prep Charter Academy for Young Men-Englewood Campus, the nation's first all-male charter public high school, was opened. In 2010 and…

  13. Swords, Shields, and the Fight for Our Children: Lessons from Urban Prep

    ERIC Educational Resources Information Center

    King, Tim

    2011-01-01

    The grim statistics are well known, but bear repeating: in Chicago, close to 60% of Black boys do not graduate from high school, and only one in forty receive a bachelor's degree by age 25. In the fall of 2006, Urban Prep Charter Academy for Young Men-Englewood Campus, the nation's first all-male charter public high school, was opened. In 2010 and…

  14. Reliability of Pattern Reversal Evoked Potentials (PREP) Using the NICOLET Pathfinder II

    DTIC Science & Technology

    1990-02-21

    different units of the same system. Further variations can occur in procedure or laboratory locations. Many researchers ( Chiappa , 1983; Colon, Visser...laboratories (Colon, et al., 1983; and Chiappa , 1983). Procedure Testing occurred over two days following the same procedure. The PREP does not vary...by the technician, 3) pupil size, 4) body temperature, or 5) small differences in electrode placement (Osken, Chiappa , and Gill, 1987). Females have

  15. QUINAULT INDIAN NATIONAL DEVELOPMENT OF TRIBAL SEAFOOD CONSUMPTION SURVEY SOFTWARE

    EPA Science Inventory

    The Quinault Indian Nation needed to determine appropriate seafood consumption rates for development of their water quality standards. EPA Region 10 and EPA's National Health and Environmental Effects Research Laboratory had been collaborating on computer assisted personal inter...

  16. QUINAULT INDIAN NATIONAL DEVELOPMENT OF TRIBAL SEAFOOD CONSUMPTION SURVEY SOFTWARE

    EPA Science Inventory

    The Quinault Indian Nation needed to determine appropriate seafood consumption rates for development of their water quality standards. EPA Region 10 and EPA's National Health and Environmental Effects Research Laboratory had been collaborating on computer assisted personal inter...

  17. Secrecy, empowerment and protection: positioning PrEP in KwaZulu-Natal, South Africa.

    PubMed

    Govender, Eliza; Mansoor, Leila; MacQueen, Kate; Abdool Karim, Quarraisha

    2017-11-01

    The release of World Health Organisation guidelines recommending the prophylactic use of daily Truvada(®) for all populations at high risk of acquiring HIV opens the way for implementation of oral pre-exposure prophylaxis (PrEP). The impact of new prevention technologies is, however, dependent on demand creation strategies such as user awareness, acceptability and access, which in turn are influenced by sociocultural and gender norms. This study was conducted in three locations in KwaZulu-Natal, urban, rural and peri-urban, with six participatory workshops. Knowledge, desirable features of a product and demand positioning for PrEP were assessed using a participatory action media research process which included art-based activities and group discussion using a semi-structured interview schedule. The data were analysed using thematic analysis. The key themes that emerged in relation to product adoption were: ability to maintain secrecy of product use; the need for agency with personal choices around HIV prevention; and an increased desire for HIV protection. Findings reaffirm the influence of user engagement in understanding the sociocultural dynamics that influence demand creation for PrEP adoption.

  18. The effect of lubricant contamination on ThinPrep (Cytyc) cervical cytology liquid-based preparations.

    PubMed

    Holton, T; Smith, D; Terry, M; Madgwick, A; Levine, T

    2008-08-01

    To assess the extent of lubricant use by smear-takers and the effect of lubricant contamination of ThinPrep processed cervical cytology samples. All primary care smear-takers were sent a questionnaire on lubricant type and frequency of use. Fifty cervical cytology samples were then contaminated with incremental amounts of K-Y jelly, 50 samples contaminated with incremental amounts of Aquagel and ten non-contaminated vials were processed using the ThinPrep T2000 processor followed by Papanicolaou staining. The morphological appearances of lubricant contamination were described microscopically and formal cell counts performed on all slides. Seventy of 94 (74.5%) primary care smear-takers indicated lubricant use of whom 9/70 (12.8%) used Aquagel and 61/70 (87.2%) used K-Y jelly. K-Y jelly appeared as mucoid blue deposits in the slide background whereas Aquagel appeared as pink stringy background material. Cell counting showed a significant difference between Aquagel and K-Y jelly contaminated slides compared to the original non-contaminated preparations for all fields and the average fields (P < 0.001) with a significantly higher count for the original non-contaminated slides than the lubricant contaminated groups. Lubricant contamination of ThinPrep cervical cytology samples may result in reduced cellularity of the subsequent slide. This study provides evidence-based data to support British Society for Clinical Cytology recommendations for no lubricant use when taking cervical samples.

  19. Survey techniques developed to align stacked beamlines at CEBAF

    SciTech Connect

    Curtis, C.J.; Oren, W.; Tremblay, K.J.

    1994-04-01

    The Continuous Electron Beam Accelerator Facility (CEBAF) in Newport News, Virginia is a new accelerator designed to produce 4 GeV 200 micro-amp continuous wave beams for nuclear physics research. It consists of two superconducting linacs each accelerating electrons by 400 MeV and linked by arcs allowing five pass recirculation. These linacs form the straight sections in a racetrack shaped accelerator contained in over 1.3 km of tunnel. The beam lines will consist of 42 superconducting accelerating cryomodules (in the linacs only), over 400 dipoles, 650 quadrupoles, and 100 sextupoles, most of the which are concentrated in the two arc sections of the machine. It is here that the single beam fine from the linacs is split into five beams of offering energy and transported to the opposite linac where it is recombined into a single beam to again pass through a linac and receive additional acceleration. These recirculation arcs are designed to maintain beam quality through a lattice which is achromatic, isochronous and whose length is equal to a multiple number of RF wavelengths. The short term relative alignment tolerances coupled with the beam fine design reflect the beam quality issues while absolute positioning determines the range of adjustment needed to match the RF phase in the linac segments. The alignment techniques which use a monumented control network as a reference, are designed to position stacked magnets and their support systems to these tolerances. Specialized procedures were tailored from existing hardware and software systems to address each phase or step of the alignment process. This allowed a relatively rapid expansion of alignment services at a new laboratory where surveying support was not seriously addressed until more then one third of the enclosure had been built.

  20. Survey Research in Athletic Training: The Scientific Method of Development and Implementation.

    PubMed

    Turocy, Paula Sammarone

    2002-12-01

    OBJECTIVE: To provide a scientific method for the development, validation, and correct use of a survey tool. BACKGROUND: Many athletic trainers are becoming involved in research to benefit either their own situations or the larger profession of athletic training. One of the most common methods used to gain this necessary information is a survey, with either a questionnaire or an interview technique. Formal instruction in the development and implementation of surveys is essential to the success of the research. As with other forms of experimental research, it is important to validate and ensure the reliability of the instruments (ie, questionnaires) used for data collection. It is also important to survey an appropriate sample of the population to ensure the appropriateness of applying the findings to the larger population. Lastly, to ensure adequate return of data, specific techniques are suggested to enhance data collection and the ability to apply the findings to the larger population. DESCRIPTION: A review of the procedures used in the development and validation of a survey instrument is provided. Information on survey-item development is provided, including types of questions, formatting, planning for data analysis, and suggestions to ensure better data acquisition and analysis. ADVANTAGES: By following the suggested procedures in this article, athletic training researchers will be able to better collect and use survey data to enhance the profession of athletic training.

  1. A Survey of Astronomical Research: A Baseline for Astronomical Development

    NASA Astrophysics Data System (ADS)

    Ribeiro, V. A. R. M.; Russo, P.; Cárdenas-Avendaño, A.

    2013-12-01

    Measuring scientific development is a difficult task. Different metrics have been put forward to evaluate scientific development; in this paper we explore a metric that uses the number of peer-reviewed, and when available non-peer-reviewed, research articles as an indicator of development in the field of astronomy. We analyzed the available publication record, using the Smithsonian Astrophysical Observatory/NASA Astrophysics Database System, by country affiliation in the time span between 1950 and 2011 for countries with a gross national income of less than 14,365 USD in 2010. This represents 149 countries. We propose that this metric identifies countries in "astronomical development" with a culture of research publishing. We also propose that for a country to develop in astronomy, it should invest in outside expert visits, send its staff abroad to study, and establish a culture of scientific publishing. Furthermore, we propose that this paper may be used as a baseline to measure the success of major international projects, such as the International Year of Astronomy 2009.

  2. A SURVEY OF ASTRONOMICAL RESEARCH: A BASELINE FOR ASTRONOMICAL DEVELOPMENT

    SciTech Connect

    Ribeiro, V. A. R. M.; Russo, P.; Cárdenas-Avendaño, A. E-mail: russo@strw.leidenuniv.nl

    2013-12-01

    Measuring scientific development is a difficult task. Different metrics have been put forward to evaluate scientific development; in this paper we explore a metric that uses the number of peer-reviewed, and when available non-peer-reviewed, research articles as an indicator of development in the field of astronomy. We analyzed the available publication record, using the Smithsonian Astrophysical Observatory/NASA Astrophysics Database System, by country affiliation in the time span between 1950 and 2011 for countries with a gross national income of less than 14,365 USD in 2010. This represents 149 countries. We propose that this metric identifies countries in ''astronomical development'' with a culture of research publishing. We also propose that for a country to develop in astronomy, it should invest in outside expert visits, send its staff abroad to study, and establish a culture of scientific publishing. Furthermore, we propose that this paper may be used as a baseline to measure the success of major international projects, such as the International Year of Astronomy 2009.

  3. Is your dog empathic? Developing a Dog Emotional Reactivity Survey.

    PubMed

    Szánthó, Flóra; Miklósi, Ádám; Kubinyi, Enikő

    2017-01-01

    toward their dogs were anthropomorphic (agreed more with the statement that "My dog thinks like a child"), perceived their dogs as more reactive to their emotions. This findings highlights the importance of testing the attitudes of the respondents when they assess the personality and the emotions of animals. The criterion validity of the Dog Emotional Reactivity Survey should be confirmed by objective behavioural tests.

  4. Is your dog empathic? Developing a Dog Emotional Reactivity Survey

    PubMed Central

    Szánthó, Flóra; Miklósi, Ádám; Kubinyi, Enikő

    2017-01-01

    attitudes toward their dogs were anthropomorphic (agreed more with the statement that “My dog thinks like a child”), perceived their dogs as more reactive to their emotions. This findings highlights the importance of testing the attitudes of the respondents when they assess the personality and the emotions of animals. The criterion validity of the Dog Emotional Reactivity Survey should be confirmed by objective behavioural tests. PMID:28192495

  5. A Survey of Professional Development for Co-Teaching

    ERIC Educational Resources Information Center

    Brown, Phillip A.

    2013-01-01

    The purpose of this exploratory study was to determine the perceptions of co-teachers concerning their professional development needs for co-teaching and to determine the level of training they received to prepare them for co-teaching. Sixty-one co-teachers (general education teachers: n = 36, 59%; special education teachers: n = 25, 41%) in the…

  6. Development, Validity, and Reliability of the Campus Residential Experience Survey

    ERIC Educational Resources Information Center

    Sriram, Rishi; Scales, Laine; Shushok, Frank, Jr.

    2017-01-01

    The importance of living on campus is well established, but extant research that examines administrator perceptions of what comprises the best educational experience for students living on campus is generally unavailable. This study reports the development of a psychometric instrument designed to uncover underlying paradigms and attitudes of…

  7. NASBE Study Group Surveys State Leadership Development Policy

    ERIC Educational Resources Information Center

    Newman, Bobbi; Hull, Robert

    2015-01-01

    State board members, working in partnership with the Consortium for Policy Research in Education (CPRE) at the University of Pennsylvania, conducted an in-depth study of states' school leadership development policies and practices. Data from this study are being analyzed to determine ways that states can create systems and structures for…

  8. Report on the Development of the University Experience Survey

    ERIC Educational Resources Information Center

    Radloff, Ali; Coates, Hamish; James, Richard; Krause, Kerri-Lee

    2011-01-01

    In 2011, the Department of Education, Employment and Workplace Relations (DEEWR) commissioned a Consortium led by the Australian Council for Educational Research (ACER) and including the University of Melbourne's Centre for the Study of Higher Education (CSHE) and the Griffith Institute for Higher Education (GIHE) to develop an instrument and…

  9. Survey-Guided Development: Data Based Organizational Change

    DTIC Science & Technology

    1975-06-01

    interactive systems including computer assisted instruction. * Improved intermediate feedback during the course of organizational development projects...34* Systemic properties in particular can improve only as a result of carefully sequenced planned interventions. "* Valid information about the state of...presented in the preceding pages appears complicated, it is because the issues involved in systematically improving large systems are complex. This reflects

  10. Use of focus group methodology in the development of an Ontario farmers' sun safety survey.

    PubMed

    Ing, Sabrina Yun; Ashbury, Fredrick D; Marrett, Loraine D; From, Lynn; Perry, Kristina V

    2002-01-01

    Farmers are at higher risk for skin cancer; US studies indicate that they do not use adequate sun protection. Little data on Canadian farmers' sun exposure are available, and a literature review suggests a strong need to develop a comprehensive, easy to complete farmers' sun safety survey in order to identify sun safety issues in the farming community. A literature review contributed to the development of a draft farmers' sun safety survey. Preliminary testing of the survey with 207 Ontario farmers supported the usefulness of the questionnaire, but weaknesses remained in phrasing and missed concepts. To augment the questionnaire's development, focus groups were held with farmers in four Ontario communities to clarify the phrasing of survey questions concerning the amount of sun exposure, the use of sun protection practices, family/personal history of skin cancer, and skin cancer attitudes and knowledge. This paper reports on what was learned substantively from these focus groups.

  11. ACCEPTABILITY OF PrEP UPTAKE AMONG RACIALLY/ETHNICALLY DIVERSE YOUNG MEN WHO HAVE SEX WITH MEN: THE P18 STUDY

    PubMed Central

    Pérez-Figueroa, Rafael E.; Kapadia, Farzana; Barton, Staci C.; Eddy, Jessica A.; Halkitis, Perry N.

    2015-01-01

    Pre-exposure prophylaxis (PrEP) is considered an effective biomedical approach for HIV prevention. However, there is limited understanding of PrEP uptake among racially/ethnically and socioeconomically diverse young men who have sex with men (YMSM). This study examined attitudes and perceptions toward PrEP uptake among YMSM by conducting semistructured interviews with a sample (N = 100) of YMSM in New York City. Thematic analysis was employed to explore key issues related to attitudes and perceptions toward PrEP utilization. Findings suggest that self-perceived risk for HIV transmission, enjoying unprotected sex, and being in a romantic relationship were associated with PrEP uptake. The most prominent barriers to PrEP uptake included costs, adherence regimen, and access. In summary, these findings underscore the importance of addressing behavioral and structural factors in maximizing the effectiveness of PrEP. In addition, PrEP implementation programs ought to consider the role of social and structural challenges to PrEP uptake and adherence among YMSM. PMID:25915697

  12. Evaluation of the Illumina ForenSeq™ DNA Signature Prep Kit - MPS forensic application for the MiSeq FGx™ benchtop sequencer.

    PubMed

    Xavier, Catarina; Parson, Walther

    2017-05-01

    Massively Parallel (Next Generation) Sequencing (MPS) technologies have recently been proven useful and successful in typing various markers relevant in forensic genetics, such as STRs, SNPs and mitochondrial genomes. Early studies investigated self-developed DNA libraries, commercially supplied kits are currently being made available to allow a smoother and gradual implementation of such technologies in forensic laboratories. The ForenSeq™ DNA Signature Prep Kit (Illumina, CA) is the first commercially available STR kit that can be used on the MiSeq FGx™ (Illumina, CA) benchtop high-throughput sequencer. This kit allows the simultaneous typing of 59 STRs and up to 172 SNPs in a single reaction and presents a short library preparation protocol adapted to contemporary forensic requirements. In this study, we evaluated the beta version of the ForenSeq DNA Signature Prep Kit MiSeq FGx system by investigating reproducibility, sensitivity, mixtures, concordance, casework-type and aDNA samples and found it to perform successfully, proving to be a robust method for future forensic applications. MPS brings the possibility of complex multiplexing, high sensitivity and sequencing resolution to forensics; however, the need for consensual directions on databasing, data storage and nomenclature must be taken into consideration.

  13. Phase transformation of "chem-prep" PZT 95/5-2Nb HF1035 ceramic under quasi-static loading conditions.

    SciTech Connect

    Montgomery, Stephen Tedford; Lee, Moo Yul; Meier, Diane A.; Hofer, John H.

    2006-07-01

    Specimens of poled and unpoled ''chem-prep'' PNZT ceramic from batch HF1035 were tested under hydrostatic, uniaxial, and constant stress difference loading conditions at -55, 25, and 75 C. The objective of this experimental study was to characterize the mechanical properties and conditions for the ferroelectric (FE) to antiferroelectric (AFE) phase transformations of this ''chem-prep'' PNZT ceramic to aid grain-scale modeling efforts in developing and testing realistic response models for use in simulation codes. As seen from a previously characterized material (batch HF803), poled ceramic from HF1035 was seen to undergo anisotropic deformation during the transition from a FE to an AFE phase. Also, the phase transformation was found to be permanent for the two low temperature conditions, whereas the transformation can be completely reversed at the highest temperature. The rates of increase in the phase transformation pressures with temperature were practically identical for both unpoled and poled PNZT HF1035 specimens. We observed that temperature spread the phase transformation over mean stress analogous to the observed spread over mean stress due to shear stress. Additionally, for poled ceramic samples, the FE to AFE phase transformation was seen to occur when the normal compressive stress, acting perpendicular to a crystallographic plane about the polar axis, equals the hydrostatic pressure at which the transformation otherwise takes place.

  14. Knowledge, attitudes and practices surveys of blood donation in developing countries.

    PubMed

    Lownik, E; Riley, E; Konstenius, T; Riley, W; McCullough, J

    2012-07-01

      Knowledge, attitude and practice (KAP) surveys have been used in many countries to understand factors that influence blood donation and as the basis for communication and donor mobilization strategies.   A search was conducted of publically available databases, and studies with the following characteristics were selected: (1) the study was a knowledge, attitude and practice or KAP plus behaviour survey; (2) the subject of the survey was blood donation; (3) the survey was performed between 1995 and 2011; and (4) the survey was performed in countries classified as emerging and developing by the International Monetary Fund.   Eighteen KAP studies conducted in seventeen developing countries were identified. There was considerable difference in the structure, population surveyed and conduct of the KAP studies. The common following themes emerged: misinformation about blood donation, fear of blood donation, willingness to donate for family and friends, concern about selling blood and a failure to transfer positive attitudes into actual blood donation.   Despite considerable differences in the culture and demographics of developing countries, several common themes emerged from different KAP surveys. © 2012 The Author(s). Vox Sanguinis © 2012 International Society of Blood Transfusion.

  15. German Graduate Student Professional Development: Report on a Survey of Perceptions (1994-95).

    ERIC Educational Resources Information Center

    Gonglewski, Margaret; Penningroth, Ann

    1998-01-01

    A survey of 188 graduate students in 28 German programs investigated students' perceptions of their own professional development for teaching or work in business or government. It examined career goals, the importance of and participation in professional development activities, relationship with advisor/mentor on professional development issues,…

  16. Workforce Development: A Survey of Industry Needs and Training Approaches

    SciTech Connect

    Ventre, Jerry; Weissman, Jane

    2009-04-01

    This paper presents information and data collected during 2008 on PV workforce needs by the Interstate Renewable Energy Council for the U.S. Department of Energy. The data was collected from licensed contractors, PV practitioners, educators and expert instructors at training sessions, and at focus group and advisory committee meetings. Respondents were primarily from three states: Florida, New York and California. Other states were represented, but to a lesser extent. For data collection, a 12-item questionnaire was developed that addressed key workforce development issues from the perspectives of both the PV industry and training institutions. A total of 63 responses were collected, although not every respondent answered every question. Industry representatives slightly outnumbered the educators, although the difference in responses was not significant.

  17. High Test-retest-reliability of pain-related evoked potentials (PREP) in healthy subjects.

    PubMed

    Özgül, Özüm Simal; Maier, Christoph; Enax-Krumova, Elena K; Vollert, Jan; Fischer, Marc; Tegenthoff, Martin; Höffken, Oliver

    2017-03-22

    Pain-related-evoked potentials (PREP) is an established electrophysiological method to evaluate the signal transmission of electrically stimulated A-delta fibres. Although prerequisite for its clinical use, test-retest-reliability and side-to-side differences of bilateral stimulation in healthy subjects have not been examined yet. We performed PREP twice within 3 to 14days in 33 healthy subjects bilaterally by stimulating the dorsal hand. Detection (DT) and pain thresholds (PT) after electrical stimulation, the corresponding pain ratings, latencies of P0, N1, P1 and N2 components and the corresponding amplitudes were assessed. Impact of electrically induced pain intensity, age, sex, and arm length on PREP was analysed. MANOVA, t-Test, interclass correlation coefficient (ICC), standard error of measurement (SEM), smallest real difference (SRD), Bland-Altmann-Analysis as well as ANCOVA were used for statistical analysis. Measurement from both sides on both days resulted in mean N1-latencies from 142.39 ±18.12ms to 144.03 ±16.62ms and in mean N1P1-amplitudes from 39.04 ±12.26μV to 40.53 ±12.9μV. Analysis of a side-to-side effect showed for the N1-latency a F-value of 0.038 and for the N1P1-amplitude of 0.004 (p >0.8). We found intraclass correlation coefficients (ICC) from 0.88 to 0.93 and a standard error of measurement (SEM) < 10% of mean values for all measurements concerning the N1-Latency and N1P1-amplitude. Intraclass correlation coefficients, standard error of measurement and Bland-Altman-Analyses revealed excellent test-retest-reliability for N1-latency and N1P1-amplitude without systematic error and there was no side-to-side effect on PREP. N1-latency (r=0.35, p <0.05) and N1P1-amplitude (r=-0.45, p <0.05) correlated with age and additionally N1-latency correlated with arm length (r=0.45, p<0.001). In contrast, pain intensity during the stimulation had no effect on both N1-latency and N1P1-amplitude. In summary, PREP showed high test

  18. Survey of state water laws affecting coal slurry pipeline development

    SciTech Connect

    Rogozen, M.B.

    1980-11-01

    This report summarizes state water laws likely to affect the development of coal slurry pipelines. It was prepared as part of a project to analyze environmental issues related to energy transportation systems. Coal slurry pipelines have been proposed as a means to expand the existing transportation system to handle the increasing coal shipments that will be required in the future. The availability of water for use in coal slurry systems in the coal-producing states is an issue of major concern.

  19. Professional Development of Officers Study. Volume 6. Survey

    DTIC Science & Technology

    1985-02-01

    as though he/she were a coach, a parent , a teacher, etc.) 8. -I-> 8. For items 9 through 16, indicate to what extent each learning experience...normally a superior, who acts as though he/she were a coach, a parent . a j., L teacher, etc.) _ REMARKS’ The "agree" scale results from combining "strongly...though he/she were a coach, a parent , a teacher, etc. Professional Development. The preparation of officers to effectively lead the Army and efficiently

  20. Vocabulary Development in European Portuguese: A Replication Study Using the Language Development Survey.

    PubMed

    Rescorla, Leslie; Nyame, Josephine; Dias, Pedro

    2016-12-01

    Our objective was to replicate previous cross-linguistic findings by comparing Portuguese and U.S. children with respect to (a) effects of language, gender, and age on vocabulary size; (b) lexical composition; and (c) late talking. We used the Language Development Survey (LDS; Rescorla, 1989) with children (18-35 months) learning European Portuguese (n = 181) and English (n = 206). In both languages, girls had higher vocabulary scores than boys and vocabulary scores increased with age. Portuguese LDS scores were significantly lower than English scores, but the effect size was small. Cross-linguistic concordance of percentage use scores yielded a Q correlation of .50, with 64 of the "top 100" words being exact matches. Cross-linguistic concordance was highest for the youngest age group. In both languages, vocabulary composition in late talkers (children ≥ 24 months with < 50 words) was highly correlated with composition in vocabulary size-matched younger children. Results replicated previous Greek, Korean, and Italian LDS studies. The early lexicons of typical talkers and late talkers contained many of the same words, indicating considerable universality and suggesting good targets for clinical intervention.