Science.gov

Sample records for prescription transfer system

  1. Constructing a Real-Time Prescription Drug Monitoring System

    PubMed Central

    Lee, Youn Tae; Jo, Emmanuel C.

    2016-01-01

    Objectives The objective of this investigation was to demonstrate the possibility of the construction of a real-time prescription drug monitoring system (PDMOS) using data from the nationwide Drug Utilization Review (DUR) system in Korea. Methods The DUR system collects information on drug prescriptions issued by healthcare practitioners and on drugs dispensed by pharmacies. PDMOS was constructed using this data. The screen of PDMOS is designed to exhibit the number of drug prescriptions, the number of prescriptions dispensed by pharmacies, and the dispensed prescription drug costs on a daily and weekly basis. Data was sourced from the DUR system between June 1, 2016 and July 18, 2016. The TOGA solution developed by the EYEQMC Co. Ltd. of Seoul, Korea was used to produce the screen shots. Results Prescription numbers by medical facilities were more numerous than the number of prescriptions dispensed by pharmacies, as expected. The number of prescriptions per day was between 2 to 3 million. The prescriptions issued by primary care clinics were most numerous, at 75% of the total number of prescriptions. Daily prescription drug costs were found to be approximately US $50 million. The prescription drug costs were highest on Mondays and were reduced towards the end of the week. Prescriptions and dispensed prescriptions numbered approximately 1,200 and 1,000 million, respectively. Conclusions The construction of a real-time PDMOS has been successful to provide daily and weekly information. There was a lag time of only one day at the national level in terms of information extraction, and scarcely any time was required to load the data. Therefore, this study highlights the potential of constructing a PDMOS to monitor the estimate the number of prescriptions and the resulting expenditures from prescriptions. PMID:27525159

  2. 21 CFR 1306.25 - Transfer between pharmacies of prescription information for Schedules III, IV, and V controlled...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... prescription pursuant to 21 CFR 1306.05 and include: (i) Date of issuance of original prescription; (ii... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Transfer between pharmacies of prescription... Substances Listed in Schedules III, IV, and V § 1306.25 Transfer between pharmacies of...

  3. A Systems Approach to Diagnostic Prescriptive Instruction.

    ERIC Educational Resources Information Center

    Kozma, Robert B.; And Others

    This five-part document presents three approaches to research on instructional improvement, with the final two sections concentrating on problems and implications for diagnostic prescriptive instruction. Part 1 reviews comparative instructional effectiveness studies. Part 2 discusses the Trait-Treatment Interaction Approach (TTI) which is…

  4. 21 CFR 1306.25 - Transfer between pharmacies of prescription information for Schedules III, IV, and V controlled...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Transfer between pharmacies of prescription... Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS Controlled..., pharmacies electronically sharing a real-time, online database may transfer up to the maximum...

  5. 21 CFR 1306.25 - Transfer between pharmacies of prescription information for Schedules III, IV, and V controlled...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Transfer between pharmacies of prescription... Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS Controlled..., pharmacies electronically sharing a real-time, online database may transfer up to the maximum...

  6. 21 CFR 1306.25 - Transfer between pharmacies of prescription information for Schedules III, IV, and V controlled...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Transfer between pharmacies of prescription... Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS Controlled..., pharmacies electronically sharing a real-time, online database may transfer up to the maximum...

  7. 21 CFR 1306.25 - Transfer between pharmacies of prescription information for Schedules III, IV, and V controlled...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Transfer between pharmacies of prescription... Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS Controlled..., pharmacies electronically sharing a real-time, online database may transfer up to the maximum...

  8. An integrated drug prescription and distribution system: challenges and opportunities.

    PubMed

    Lanssiers, R; Everaert, E; De Win, M; Van De Velde, R; De Clercq, H

    2002-01-01

    Using the hospital's drug prescription and distribution system as a guide, benefits and drawbacks of a medical activity management system that is tightly integrated with the supply chain management of a hospital will be discussed from the point of view of various participating healthcare actors. PMID:15058416

  9. Transfer system

    DOEpatents

    Kurosawa, Kanji; Koga, Bunichiro; Ito, Hideki; Kiriyama, Shigeru; Higuchi, Shizuo

    2003-05-20

    A transport system includes a traveling rail (1) which constitutes a transport route and a transport body (3) which is capable of traveling on the traveling rail in the longitudinal direction of the traveling rail. Flexible drive tubes (5) are arranged on the traveling rail in the longitudinal direction of the traveling rail. The transport body includes a traveling wheel (4) which is capable of rolling on the traveling rail and drive wheels (2) which are capable of rolling on the drive tubes upon receiving the rotational drive power generated by pressure of a pressure medium supplied to the drive tubes while depressing the drive tubes. The traveling rail includes a plurality of transport sections and the transport body is capable of receiving a rotational drive force from the drive tubes at every transport sections. If necessary, a transport route changeover switch which changes over the transport route can be provided between the transport sections.

  10. [Analysis on traditional Chinese medicine prescriptions treating cancer based on traditional Chinese medicine inheritance assistance system and discovery of new prescriptions].

    PubMed

    Yu, Ming; Cao, Qi-chen; Su, Yu-xi; Sui, Xin; Yang, Hong-jun; Huang, Lu-qi; Wang, Wen-ping

    2015-08-01

    Malignant tumor is one of the main causes for death in the world at present as well as a major disease seriously harming human health and life and restricting the social and economic development. There are many kinds of reports about traditional Chinese medicine patent prescriptions, empirical prescriptions and self-made prescriptions treating cancer, and prescription rules were often analyzed based on medication frequency. Such methods were applicable for discovering dominant experience but hard to have an innovative discovery and knowledge. In this paper, based on the traditional Chinese medicine inheritance assistance system, the software integration of mutual information improvement method, complex system entropy clustering and unsupervised entropy-level clustering data mining methods was adopted to analyze the rules of traditional Chinese medicine prescriptions for cancer. Totally 114 prescriptions were selected, the frequency of herbs in prescription was determined, and 85 core combinations and 13 new prescriptions were indentified. The traditional Chinese medicine inheritance assistance system, as a valuable traditional Chinese medicine research-supporting tool, can be used to record, manage, inquire and analyze prescription data.

  11. A smart-card-enabled privacy preserving E-prescription system.

    PubMed

    Yang, Yanjiang; Han, Xiaoxi; Bao, Feng; Deng, Robert H

    2004-03-01

    Within the overall context of protection of health care information, privacy of prescription data needs special treatment. First, the involvement of diverse parties, especially nonmedical parties in the process of drug prescription complicates the protection of prescription data. Second, both patients and doctors have privacy stakes in prescription, and their privacy should be equally protected. Third, the following facts determine that prescription should not be processed in a truly anonymous manner: certain involved parties conduct useful research on the basis of aggregation of prescription data that are linkable with respect to either the patients or the doctors; prescription data has to be identifiable in some extreme circumstances, e.g., under the court order for inspection and assign liability. In this paper, we propose an e-prescription system to address issues pertaining to the privacy protection in the process of drug prescription. In our system, patients' smart cards play an important role. For one thing, the smart cards are implemented to be portable repositories carrying up-to-date personal medical records and insurance information, providing doctors instant data access crucial to the process of diagnosis and prescription. For the other, with the secret signing key being stored inside, the smart card enables the patient to sign electronically the prescription pad, declaring his acceptance of the prescription. To make the system more realistic, we identify the needs for a patient to delegate his signing capability to other people so as to protect the privacy of information housed on his card. A strong proxy signature scheme achieving technologically mutual agreements on the delegation is proposed to implement the delegation functionality.

  12. Heat transfer system

    DOEpatents

    McGuire, Joseph C.

    1982-01-01

    A heat transfer system for a nuclear reactor. Heat transfer is accomplished within a sealed vapor chamber which is substantially evacuated prior to use. A heat transfer medium, which is liquid at the design operating temperatures, transfers heat from tubes interposed in the reactor primary loop to spaced tubes connected to a steam line for power generation purposes. Heat transfer is accomplished by a two-phase liquid-vapor-liquid process as used in heat pipes. Condensible gases are removed from the vapor chamber through a vertical extension in open communication with the chamber interior.

  13. Heat transfer system

    DOEpatents

    Not Available

    1980-03-07

    A heat transfer system for a nuclear reactor is described. Heat transfer is accomplished within a sealed vapor chamber which is substantially evacuated prior to use. A heat transfer medium, which is liquid at the design operating temperatures, transfers heat from tubes interposed in the reactor primary loop to spaced tubes connected to a steam line for power generation purposes. Heat transfer is accomplished by a two-phase liquid-vapor-liquid process as used in heat pipes. Condensible gases are removed from the vapor chamber through a vertical extension in open communication with the chamber interior.

  14. Fuel transfer system

    DOEpatents

    Townsend, Harold E.; Barbanti, Giancarlo

    1994-01-01

    A nuclear fuel bundle fuel transfer system includes a transfer pool containing water at a level above a reactor core. A fuel transfer machine therein includes a carriage disposed in the transfer pool and under the water for transporting fuel bundles. The carriage is selectively movable through the water in the transfer pool and individual fuel bundles are carried vertically in the carriage. In a preferred embodiment, a first movable bridge is disposed over an upper pool containing the reactor core, and a second movable bridge is disposed over a fuel storage pool, with the transfer pool being disposed therebetween. A fuel bundle may be moved by the first bridge from the reactor core and loaded into the carriage which transports the fuel bundle to the second bridge which picks up the fuel bundle and carries it to the fuel storage pool.

  15. Fuel transfer system

    DOEpatents

    Townsend, H.E.; Barbanti, G.

    1994-03-01

    A nuclear fuel bundle fuel transfer system includes a transfer pool containing water at a level above a reactor core. A fuel transfer machine therein includes a carriage disposed in the transfer pool and under the water for transporting fuel bundles. The carriage is selectively movable through the water in the transfer pool and individual fuel bundles are carried vertically in the carriage. In a preferred embodiment, a first movable bridge is disposed over an upper pool containing the reactor core, and a second movable bridge is disposed over a fuel storage pool, with the transfer pool being disposed therebetween. A fuel bundle may be moved by the first bridge from the reactor core and loaded into the carriage which transports the fuel bundle to the second bridge which picks up the fuel bundle and carries it to the fuel storage pool. 6 figures.

  16. A security and privacy preserving e-prescription system based on smart cards.

    PubMed

    Hsu, Chien-Lung; Lu, Chung-Fu

    2012-12-01

    In 2002, Ateniese and Medeiros proposed an e-prescription system, in which the patient can store e-prescription and related information using smart card. Latter, Yang et al. proposed a novel smart-card based e-prescription system based on Ateniese and Medeiros's system in 2004. Yang et al. considered the privacy issues of prescription data and adopted the concept of a group signature to provide patient's privacy protection. To make the e-prescription system more realistic, they further applied a proxy signature to allow a patient to delegate his signing capability to other people. This paper proposed a novel security and privacy preserving e-prescription system model based on smart cards. A new role, chemist, is included in the system model for settling the medicine dispute. We further presented a concrete identity-based (ID-based) group signature scheme and an ID-based proxy signature scheme to realize the proposed model. Main property of an ID-based system is that public key is simple user's identity and can be verified without extra public key certificates. Our ID-based group signature scheme can allow doctors to sign e-prescription anonymously. In a case of a medical dispute, identities of the doctors can be identified. The proposed ID-based proxy signature scheme can improve signing delegation and allows a delegation chain. The proposed e-prescription system based on our proposed two cryptographic schemes is more practical and efficient than Yang et al.'s system in terms of security, communication overheads, computational costs, practical considerations.

  17. A security and privacy preserving e-prescription system based on smart cards.

    PubMed

    Hsu, Chien-Lung; Lu, Chung-Fu

    2012-12-01

    In 2002, Ateniese and Medeiros proposed an e-prescription system, in which the patient can store e-prescription and related information using smart card. Latter, Yang et al. proposed a novel smart-card based e-prescription system based on Ateniese and Medeiros's system in 2004. Yang et al. considered the privacy issues of prescription data and adopted the concept of a group signature to provide patient's privacy protection. To make the e-prescription system more realistic, they further applied a proxy signature to allow a patient to delegate his signing capability to other people. This paper proposed a novel security and privacy preserving e-prescription system model based on smart cards. A new role, chemist, is included in the system model for settling the medicine dispute. We further presented a concrete identity-based (ID-based) group signature scheme and an ID-based proxy signature scheme to realize the proposed model. Main property of an ID-based system is that public key is simple user's identity and can be verified without extra public key certificates. Our ID-based group signature scheme can allow doctors to sign e-prescription anonymously. In a case of a medical dispute, identities of the doctors can be identified. The proposed ID-based proxy signature scheme can improve signing delegation and allows a delegation chain. The proposed e-prescription system based on our proposed two cryptographic schemes is more practical and efficient than Yang et al.'s system in terms of security, communication overheads, computational costs, practical considerations. PMID:22407399

  18. E-prescription as a tool for improving services and the financial viability of healthcare systems: the case of the Greek national e-prescription system.

    PubMed

    Pangalos, G; Sfyroeras, V; Pagkalos, I

    2014-01-01

    E-prescription systems can help improve patient service, safety and quality of care. They can also help achieve better compliance for the patients and better alignment with the guidelines for the practitioners. The recently implemented national e-prescription system in Greece already covers approximately 85% of all prescriptions prescribed in Greece today (approximately 5.5 million per month). The system has not only contributed already in significant changes towards improving services and better monitoring and planning of public health, but also substantially helped to contain unnecessary expenditure related to medication use and improve transparency and administrative control. Such issues have gained increasing importance not only for Greece but also for many other national healthcare systems that have to cope with the continuous rise of medication expenditure. Our implementation has, therefore, shown that besides their importance for improving services, national e-prescription systems can also provide a valuable tool for better utilisation of resources and for containing unnecessary healthcare costs, thus contributing to the improvement of the financial stability and viability of the overall healthcare system.

  19. E-prescription as a tool for improving services and the financial viability of healthcare systems: the case of the Greek national e-prescription system.

    PubMed

    Pangalos, G; Sfyroeras, V; Pagkalos, I

    2014-01-01

    E-prescription systems can help improve patient service, safety and quality of care. They can also help achieve better compliance for the patients and better alignment with the guidelines for the practitioners. The recently implemented national e-prescription system in Greece already covers approximately 85% of all prescriptions prescribed in Greece today (approximately 5.5 million per month). The system has not only contributed already in significant changes towards improving services and better monitoring and planning of public health, but also substantially helped to contain unnecessary expenditure related to medication use and improve transparency and administrative control. Such issues have gained increasing importance not only for Greece but also for many other national healthcare systems that have to cope with the continuous rise of medication expenditure. Our implementation has, therefore, shown that besides their importance for improving services, national e-prescription systems can also provide a valuable tool for better utilisation of resources and for containing unnecessary healthcare costs, thus contributing to the improvement of the financial stability and viability of the overall healthcare system. PMID:25161106

  20. Orbital Fluid Transfer System

    NASA Technical Reports Server (NTRS)

    Johnston, A. S., (Nick); Ryder, Mel; Tyler, Tony R.

    1998-01-01

    An automated fluid and power interface system needs to be developed for future space missions which require on orbit consumable replenishment. Current method of fluid transfer require manned vehicles and extravehicular activity. Currently the US does not have an automated capability for consumable transfer on-orbit. This technology would benefit both Space Station and long duration satellites. In order to provide this technology the Automated Fluid Interface System (AFIS) was developed. The AFIS project was an advanced development program aimed at developing a prototype satellite servicer for future space operations. This mechanism could transfer propellants, cryogens, fluids, gasses, electrical power, and communications from a tanker unit to the orbiting satellite. The development of this unit was a cooperative effort between Marshall Space Flight Center in Huntsville, Alabama, and Moog, Inc. in East Aurora, New York. An engineering model was built and underwent substantial development testing at Marshall Space Flight Center (MSFC). While the AFIS is not suitable for spaceflight, testing and evaluation of the AFIS provided significant experience which would be beneficial in building a flight unit. The lessons learned from testing the AFIS provided the foundation for the next generation fluid transfer mechanism, the Orbital Fluid Transfer System (OFTS). The OFTS project was a study contract with MSFC and Moog, Inc. The OFTS was designed for the International Space Station (ISS), but its flexible design could used for long duration satellite missions and other applications. The OFTS was designed to be used after docking. The primary function was to transfer bipropellants and high pressure gases. The other items addressed by this task included propellant storage, hardware integration, safety and control system issues. A new concept for high pressure couplings was also developed. The results of the AFIS testing provided an excellent basis for the OFTS design. The OFTS

  1. Development of clinical application for a nutritional prescription support system for total parenteral/enteral nutrition.

    PubMed

    Masuda, Syuzo; Oka, Ryusho; Uwai, Koji; Matsuda, Yumi; Shiraishi, Tadashi; Nakagawa, Yoshito; Shoji, Tohru; Mihara, Chie; Takeshita, Mitsuhiro; Ozawa, Koichiro

    2009-09-01

    One of the important roles of pharmacists as members of a nutrition support team is nutritional prescription support. We developed a nutritional prescription support system (NPSS) that facilitates prescription support and analysis and evaluated its usefulness in nutritional therapy. An NPSS for prescription support and the management of patient information was created. With this NPSS, the nutritional status was assessed, and, on the basis of the results, such variables as the total energy expenditure were calculated. This system allows prescription support for parenteral nutrition (PN) therapy, enteral nutrition (EN) therapy, and the transition period between them. This system was used for 2 representative patients and evaluated. In a malnourished patient receiving oral warfarin, EN solutions were compared by means of the NPSS, and an appropriate EN solution was selected. In addition, the prothrombin time-international normalized ratio was monitored, and favorable results were obtained regarding the adjustment of the warfarin dose and nutritional management. In a patient with aspiration pneumonia, continuous nutritional management to EN from PN therapy was straightforwardly performed with the NPSS. This NPSS allows rapid, comprehensive nutritional management during the transition period to EN from PN therapy, despite these therapies being considered separately in conventional nutritional management. The NPSS is useful for simplifying prescription support and facilitating information sharing among members of a nutrition support team.

  2. Intelligent diagnosis and prescription for a customized physical fitness and healthcare system.

    PubMed

    Huang, Chung-Chi; Liu, Hsiao-Man; Huang, Chung-Lin

    2015-01-01

    With the advent of the era of global high-tech industry and commerce and its associated sedentary lifestyle, opportunities for physical activity are reduced. People's physical fitness and health is deteriorating. Therefore, it is necessary to develop a system that can enhance people's physical fitness and health. However, it is difficult for general physical fitness and healthcare systems to meet individualized needs. The main purpose of this research is to develop a method of intelligent diagnosis and prescription for a customized physical fitness and healthcare system. The proposed system records all processes of the physical fitness and healthcare system via a wireless sensor network and the results of the diagnosis and prescription will be generated by fuzzy logic inference. It will improve individualized physical fitness and healthcare. Finally, we demonstrate the advantages of intelligent diagnosis and prescription for a customized physical fitness and healthcare system.

  3. Intelligent diagnosis and prescription for a customized physical fitness and healthcare system.

    PubMed

    Huang, Chung-Chi; Liu, Hsiao-Man; Huang, Chung-Lin

    2015-01-01

    With the advent of the era of global high-tech industry and commerce and its associated sedentary lifestyle, opportunities for physical activity are reduced. People's physical fitness and health is deteriorating. Therefore, it is necessary to develop a system that can enhance people's physical fitness and health. However, it is difficult for general physical fitness and healthcare systems to meet individualized needs. The main purpose of this research is to develop a method of intelligent diagnosis and prescription for a customized physical fitness and healthcare system. The proposed system records all processes of the physical fitness and healthcare system via a wireless sensor network and the results of the diagnosis and prescription will be generated by fuzzy logic inference. It will improve individualized physical fitness and healthcare. Finally, we demonstrate the advantages of intelligent diagnosis and prescription for a customized physical fitness and healthcare system. PMID:26444803

  4. Wireless power transfer system

    DOEpatents

    Wu, Hunter; Sealy, Kylee; Gilchrist, Aaron

    2016-02-23

    A system includes a first stage of an inductive power transfer system with an LCL load resonant converter with a switching section, an LCL tuning circuit, and a primary receiver pad. The IPT system includes a second stage with a secondary receiver pad, a secondary resonant circuit, a secondary rectification circuit, and a secondary decoupling converter. The secondary receiver pad connects to the secondary resonant circuit. The secondary resonant circuit connects to the secondary rectification circuit. The secondary rectification circuit connects to the secondary decoupling converter. The second stage connects to a load. The load includes an energy storage element. The second stage and load are located on a vehicle and the first stage is located at a fixed location. The primary receiver pad wirelessly transfers power to the secondary receiver pad across a gap when the vehicle positions the secondary receiver pad with respect to the primary receiver pad.

  5. CURRENT TRANSFER SYSTEMS

    DOEpatents

    Watt, D.A.

    1956-07-01

    A current transfer system is described for transferring current between a rotating member and a co-axial stationary member. The particular area of application for the invention is in connection with homopolar generators where a low voltage and high current are generated. The current tramsfer system of the invention comprises a rotor member and a co-axial stator member wherein one of the members is shaped to provide a circumferential surface concave in section and the other member is shaped to have a peripheral portion in close proximity to the surface, whereby a liquid metal can be stably supported between the two members when they are moving relative to one another to establish an electrical conducting path between the members.

  6. Thermal flux transfer system

    NASA Technical Reports Server (NTRS)

    Freggens, R. A. (Inventor)

    1973-01-01

    A thermal flux transfer system for use in maintaining the thrust chamber of an operative reaction motor at given temperatures is described. The system is characterized by an hermetically sealed chamber surrounding a thrust chamber to be cooled, with a plurality of parallel, longitudinally spaced, disk-shaped wick members formed of a metallic mesh and employed in delivering a working fluid, in its liquid state, radially toward the thrust chamber and delivering the working fluid, in its vapor state, away from the nozzle for effecting a cooling of the nozzle, in accordance with known principles of an operating heat pipe.

  7. Simple prescription for computing the interparticle potential energy for D-dimensional gravity systems

    NASA Astrophysics Data System (ADS)

    Accioly, Antonio; Helayël-Neto, José; Barone, F. E.; Herdy, Wallace

    2015-02-01

    A straightforward prescription for computing the D-dimensional potential energy of gravitational models, which is strongly based on the Feynman path integral, is built up. Using this method, the static potential energy for the interaction of two masses is found in the context of D-dimensional higher-derivative gravity models, and its behavior is analyzed afterwards in both ultraviolet and infrared regimes. As a consequence, two new gravity systems in which the potential energy is finite at the origin, respectively, in D = 5 and D = 6, are found. Since the aforementioned prescription is equivalent to that based on the marriage between quantum mechanics (to leading order, i.e., in the first Born approximation) and the nonrelativistic limit of quantum field theory, and bearing in mind that the latter relies basically on the calculation of the nonrelativistic Feynman amplitude ({{M}NR}), a trivial expression for computing {{M}NR} is obtained from our prescription as an added bonus.

  8. 76 FR 29765 - Determination of System Attributes for the Tracking and Tracing of Prescription Drugs; Reopening...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-23

    ... HUMAN SERVICES Food and Drug Administration Determination of System Attributes for the Tracking and Tracing of Prescription Drugs; Reopening of the Comment Period AGENCY: Food and Drug Administration, HHS. ACTION: Notice; reopening of the comment period. ] SUMMARY: The Food and Drug Administration (FDA)...

  9. 76 FR 1182 - Determination of System Attributes for the Tracking and Tracing of Prescription Drugs; Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-07

    ... supply chain. On September 27, 2007, the Food and Drug Administration Amendments Act of 2007 (FDAAA) (Pub... HUMAN SERVICES Food and Drug Administration Determination of System Attributes for the Tracking and Tracing of Prescription Drugs; Public Workshop AGENCY: Food and Drug Administration, HHS. ACTION:...

  10. [Analysis on prescription rules of treating senile dementia based on traditional Chinese medicine inheritance auxiliary systems].

    PubMed

    Zong, Xin; Ji, Xu-Ming; Wei, Feng-Qin; Shi, Zuo-Rong

    2014-02-01

    This is designed to analyze and summarize medication rules for treating senile dementia with Chinese medicine in CNKI according to the traditional Chinese medicine (TCM) inheritance auxiliary system. Collect documents in CNKI that account treating senile dementia with Chinese formula; filter and establish a formula database, and then to search for medication rules on the TCM inheritance auxiliary system. It is filtered that 104 formulas are used for treating senile dementia screening treat senile dementia, involving 147 kinds of Chinese medicine. Tonic medicine are most frequently used, followed by the medicine of activating blood circulation and resuscitating; medicine pair most used is Ligusticum chuanxiong Hort-Acorus tatarinowii, accounting for 27.9% of all formula. And then 8 core pairs and 4 new formulas are evolved. Analysis on formulas for treating senile dementia filtered form CNKI by TCM inheritance auxiliary system shows prescription is mainly tonifying, activating blood circulation and resuscitating, that reveals prescription rules, to provide a reference for clinical treatment.

  11. Heat transfer in aeropropulsion systems

    NASA Astrophysics Data System (ADS)

    Simoneau, R. J.

    1985-07-01

    Aeropropulsion heat transfer is reviewed. A research methodology based on a growing synergism between computations and experiments is examined. The aeropropulsion heat transfer arena is identified as high Reynolds number forced convection in a highly disturbed environment subject to strong gradients, body forces, abrupt geometry changes and high three dimensionality - all in an unsteady flow field. Numerous examples based on heat transfer to the aircraft gas turbine blade are presented to illustrate the types of heat transfer problems which are generic to aeropropulsion systems. The research focus of the near future in aeropropulsion heat transfer is projected.

  12. Heat transfer in aeropropulsion systems

    NASA Technical Reports Server (NTRS)

    Simoneau, R. J.

    1985-01-01

    Aeropropulsion heat transfer is reviewed. A research methodology based on a growing synergism between computations and experiments is examined. The aeropropulsion heat transfer arena is identified as high Reynolds number forced convection in a highly disturbed environment subject to strong gradients, body forces, abrupt geometry changes and high three dimensionality - all in an unsteady flow field. Numerous examples based on heat transfer to the aircraft gas turbine blade are presented to illustrate the types of heat transfer problems which are generic to aeropropulsion systems. The research focus of the near future in aeropropulsion heat transfer is projected.

  13. Design of a RESTful web information system for drug prescription and administration.

    PubMed

    Bianchi, Lorenzo; Paganelli, Federica; Pettenati, Maria Chiara; Turchi, Stefano; Ciofi, Lucia; Iadanza, Ernesto; Giuli, Dino

    2014-05-01

    Drug prescription and administration processes strongly impact on the occurrence of risks in medical settings for they can be sources of adverse drug events (ADEs). A properly engineered use of information and communication technologies has proven to be a promising approach to reduce these risks. In this study, we propose PHARMA, a web information system which supports healthcare staff in the secure cooperative execution of drug prescription, transcription and registration tasks. PHARMA allows the easy sharing and management of documents containing drug-related information (i.e., drug prescriptions, medical reports, screening), which is often inconsistent and scattered across different information systems and heterogeneous organization domains (e.g., departments, other hospital facilities). PHARMA enables users to access such information in a consistent and secure way, through the adoption of REST and web-oriented design paradigms and protocols. We describe the implementation of the PHARMA prototype, and we discuss the results of the usability evaluation that we carried out with the staff of a hospital in Florence, Italy.

  14. CANISTER TRANSFER SYSTEM DESCRIPTION DOCUMENT

    SciTech Connect

    B. Gorpani

    2000-06-23

    The Canister Transfer System receives transportation casks containing large and small disposable canisters, unloads the canisters from the casks, stores the canisters as required, loads them into disposal containers (DCs), and prepares the empty casks for re-shipment. Cask unloading begins with cask inspection, sampling, and lid bolt removal operations. The cask lids are removed and the canisters are unloaded. Small canisters are loaded directly into a DC, or are stored until enough canisters are available to fill a DC. Large canisters are loaded directly into a DC. Transportation casks and related components are decontaminated as required, and empty casks are prepared for re-shipment. One independent, remotely operated canister transfer line is provided in the Waste Handling Building System. The canister transfer line consists of a Cask Transport System, Cask Preparation System, Canister Handling System, Disposal Container Transport System, an off-normal canister handling cell with a transfer tunnel connecting the two cells, and Control and Tracking System. The Canister Transfer System operating sequence begins with moving transportation casks to the cask preparation area with the Cask Transport System. The Cask Preparation System prepares the cask for unloading and consists of cask preparation manipulator, cask inspection and sampling equipment, and decontamination equipment. The Canister Handling System unloads the canister(s) and places them into a DC. Handling equipment consists of a bridge crane hoist, DC loading manipulator, lifting fixtures, and small canister staging racks. Once the cask has been unloaded, the Cask Preparation System decontaminates the cask exterior and returns it to the Carrier/Cask Handling System via the Cask Transport System. After the DC is fully loaded, the Disposal Container Transport System moves the DC to the Disposal Container Handling System for welding. To handle off-normal canisters, a separate off-normal canister handling

  15. Power Transfer in Physical Systems.

    ERIC Educational Resources Information Center

    Kaeck, Jack A.

    1990-01-01

    Explores the power transfer using (1) a simple electric circuit consisting of a power source with internal resistance; (2) two different mechanical systems (gravity driven and constant force driven); (3) ecological examples; and (4) a linear motor. (YP)

  16. Co-Design of a Computer-Assisted Medical Decision Support System to Manage Antibiotic Prescription in an ICU Ward.

    PubMed

    Gil, Miguel; Pinto, Pedro; Simões, Alexandra S; Póvoa, Pedro; Da Silva, Miguel Mira; Lapão, Luís Velez

    2016-01-01

    About 37 thousand people die per year in Europe due to infections by resistant bacteria. Fighting antimicrobial resistances (AR) is a top priority to save lives and reduce costs. AR is triggered mostly by uncritical antibiotic prescription. This paper presents HAITool, a decision-making information system to support antibiotic prescription. The system was co-developed together with health professionals using Design Science Research Methodology, empowered with innovative data visualization techniques to improve AR management. HAITool includes integrated visualizations of patient, microbiology, and pharmacy data, facilitating clinical decision support, antibiotic prescriptions quality and antibiotic-resistant bacteria monitoring. It also includes an alert module that monitors conformance of antibiotic prescriptions with norms and guidelines. HAITool is evaluated using both the Österle principles and interviews with physicians and infection control team from three participant hospitals. PMID:27577433

  17. [Analysis on prescription rules of treating senile dementia based on traditional Chinese medicine inheritance auxiliary systems].

    PubMed

    Zong, Xin; Ji, Xu-Ming; Wei, Feng-Qin; Shi, Zuo-Rong

    2014-02-01

    This is designed to analyze and summarize medication rules for treating senile dementia with Chinese medicine in CNKI according to the traditional Chinese medicine (TCM) inheritance auxiliary system. Collect documents in CNKI that account treating senile dementia with Chinese formula; filter and establish a formula database, and then to search for medication rules on the TCM inheritance auxiliary system. It is filtered that 104 formulas are used for treating senile dementia screening treat senile dementia, involving 147 kinds of Chinese medicine. Tonic medicine are most frequently used, followed by the medicine of activating blood circulation and resuscitating; medicine pair most used is Ligusticum chuanxiong Hort-Acorus tatarinowii, accounting for 27.9% of all formula. And then 8 core pairs and 4 new formulas are evolved. Analysis on formulas for treating senile dementia filtered form CNKI by TCM inheritance auxiliary system shows prescription is mainly tonifying, activating blood circulation and resuscitating, that reveals prescription rules, to provide a reference for clinical treatment. PMID:25204138

  18. Prescription Drugs

    MedlinePlus

    ... body, especially in brain areas involved in the perception of pain and pleasure. Prescription stimulants , such as ... of drug that causes changes in your mood, perceptions, and behavior can affect judgment and willingness to ...

  19. Assessment of clinical outcomes of Roth and MBT bracket prescription using the American Board of Orthodontics Objective Grading System

    PubMed Central

    Jain, Mahesh; Varghese, Joseph; Mascarenhas, Rohan; Mogra, Subraya; Shetty, Siddarth; Dhakar, Nidhi

    2013-01-01

    Background: There is always a need to assess whether small changes in bracket prescription can lead to visually detectable differences in tooth positions. However, with little clinical evidence to show advantages of any of the popularly used bracket systems, orthodontists are forced to make clinical decisions with little scientific guidance. Aim: To compare the orthodontic cases finished with Roth and MBT prescription using American Board of Orthodontics-Objective Grading System (ABO-OGS). Settings and Design: Department of Orthodontics, Post-graduate dental college, retrospective cross-sectional study. Materials and Methods: Forty patients selected were divided into two groups of 20 patients each finished with straight wire appliance using Roth and MBT prescription, respectively. The examiner ability was assessed and calibrated by one of the ABO certified clinician to grade cases using the OGS. Statistical Analysis: Unpaired student t-test was used and P < 0.05 was accepted as significant. Results and Conclusions: MBT bracket group had a lower score of 2.60 points in buccolingual inclination and lower score of 1.10 points in occlusal contact category that was statistically significant when compared with Roth group. The difference in total ABO-OGS score was 2.65 points showing that the outcome for the MBT prescription was better than that of the Roth prescription, which is statistically significant, but with little or no clinical significance. It can be concluded that use of either one of the Roth and MBT bracket prescriptions have no impact to the overall clinical outcome and quality of treatment entirely depends on clinician judgment and experience. PMID:24124295

  20. Optical fiber data transfer system

    NASA Technical Reports Server (NTRS)

    Mcmillan, S. H.

    1988-01-01

    This Phase 2 effort applies the results of Phase 1 to design and fabricate an optical slip ring system for a helicopter rotor blade/wind tunnel application. In this application, there are two assemblies: one on the rotating portion of the mechanical system, one on the stationary portion. The assembly on the rotating portion digitizes and encodes 128 transducer signals from various parts of the blade, and optically transfers data across the noncontacting coupling. Two complete identical independent channels are provided. On the stationary side, the signals are decoded and one channel is transmitted in digital form to a computer for recording and analysis. The second channel reconstructs the analog transducer signals for real time observation. In the opposite direction, eight signal channels enable control signals to be passed from the stationary to the rotating part of the system. Power to the rotor mounted electronics is supplied via power slip rings. The advantages of the optical over the traditional electro-mechanical slip ring method of data transfer across a rotating joint are long life, low-maintenance, immunity to crosstalk, and wider bandwidth. Successful completion of this effort demonstrated that this method is practical and reliable, and can be implemented under difficult conditions of available space, power, environment, and stringent performance and equipment life requirements.

  1. Optical fiber data transfer system

    NASA Astrophysics Data System (ADS)

    McMillan, S. H.

    1988-09-01

    This Phase 2 effort applies the results of Phase 1 to design and fabricate an optical slip ring system for a helicopter rotor blade/wind tunnel application. In this application, there are two assemblies: one on the rotating portion of the mechanical system, one on the stationary portion. The assembly on the rotating portion digitizes and encodes 128 transducer signals from various parts of the blade, and optically transfers data across the noncontacting coupling. Two complete identical independent channels are provided. On the stationary side, the signals are decoded and one channel is transmitted in digital form to a computer for recording and analysis. The second channel reconstructs the analog transducer signals for real time observation. In the opposite direction, eight signal channels enable control signals to be passed from the stationary to the rotating part of the system. Power to the rotor mounted electronics is supplied via power slip rings. The advantages of the optical over the traditional electro-mechanical slip ring method of data transfer across a rotating joint are long life, low-maintenance, immunity to crosstalk, and wider bandwidth. Successful completion of this effort demonstrated that this method is practical and reliable, and can be implemented under difficult conditions of available space, power, environment, and stringent performance and equipment life requirements.

  2. Smart crane ammunition transfer system

    SciTech Connect

    Bradley, E.C.; Killough, S.M.; Rowe, J.C.

    1995-03-01

    The purpose of the Smart Crane Ammunition Transfer System (SCATS) project is to demonstrate robotic/telerobotic controls technology for a mobile articulated crane for missile/ munitions handling, delivery, and reload. Missile resupply and reload have been manually intensive operations up to this time. Currently, reload missiles are delivered by truck to the site of the launcher. A crew of four to five personnel reloads the missiles from the truck to the launcher using a hydraulic-powered crane. The missiles are handled carefully for the safety of the missiles and personnel. Numerous steps are required in the reload process and the entire reload operation can take over 1 h for some missile systems. Recent U.S. Army directives require the entire operation to be accomplished in a fraction of that time. Current requirements for the development of SCATS are being based primarily on reloading Patriot missiles. The planned development approach will integrate robotic control and sensor technology with a commercially available hydraulic articulated crane. SCATS is being developed with commercially available hardware as much as possible. Development plans include adding a 3-D.F. end effector with a grapple to the articulating crane; closed-loop position control for the crane and end effector; digital microprocessor control of crane functions; simplified operator interface; and operating modes which include rectilinear movement, obstacle avoidance, and partial automated operation. The planned development will include progressive technology demonstrations. Ultimate plans are for this technology to be transferred and utilized in the military fielding process.

  3. Waste Feed Delivery Transfer System Analysis

    SciTech Connect

    JULYK, L.J.

    2000-05-05

    This document provides a documented basis for the required design pressure rating and pump pressure capacity of the Hanford Site waste-transfer system in support of the waste feed delivery to the privatization contractor for vitrification. The scope of the analysis includes the 200 East Area double-shell tank waste transfer pipeline system and the associated transfer system pumps for a11 Phase 1B and Phase 2 waste transfers from AN, AP, AW, AY, and A2 Tank Farms.

  4. [Establishment of three-dimensional integrated "serum pharmacochemistry-pharmacokinetics (pharmacodynamics)-systems biology" for research of traditional Chinese medicine prescription and its application in Yinchenhao Tang].

    PubMed

    Zhang, Ai-Hua; Sun, Hui; Yan, Guang-Li; Han, Ying; Wang, Xi-Jun

    2013-11-01

    Traditional Chinese medicine (TCM) prescription is a valuable asset for clinical medication, has multi-component and multi-target characteristics. However, due to the complex ingredients of prescription, the unclear mechanism, the lack of scientific data to support the dose-response relationship, it has become the bottleneck for the in-depth study for the process of modernization and internationalization of TCM. It requires the integration of Chinese medicine theory, modern analysis and data mining technology to build new research model for characteristic of TCM prescription. This paper provides an overview of TCM serum pharmacochemistry, pharmacokinetics (pharmacodynamics) and systems biology theory and practice, to establish the integrated three-dimensional "serum pharmacochemistry-pharmacokinetics (pharmacodynamics)-systems biology" for the research of TCM prescription to reveal the pharma-material basis and action mechanism and the compatibility scientific connotation, with a prescription Yinchenhao Tang as a case study.

  5. [Establishment of three-dimensional integrated "serum pharmacochemistry-pharmacokinetics (pharmacodynamics)-systems biology" for research of traditional Chinese medicine prescription and its application in Yinchenhao Tang].

    PubMed

    Zhang, Ai-Hua; Sun, Hui; Yan, Guang-Li; Han, Ying; Wang, Xi-Jun

    2013-11-01

    Traditional Chinese medicine (TCM) prescription is a valuable asset for clinical medication, has multi-component and multi-target characteristics. However, due to the complex ingredients of prescription, the unclear mechanism, the lack of scientific data to support the dose-response relationship, it has become the bottleneck for the in-depth study for the process of modernization and internationalization of TCM. It requires the integration of Chinese medicine theory, modern analysis and data mining technology to build new research model for characteristic of TCM prescription. This paper provides an overview of TCM serum pharmacochemistry, pharmacokinetics (pharmacodynamics) and systems biology theory and practice, to establish the integrated three-dimensional "serum pharmacochemistry-pharmacokinetics (pharmacodynamics)-systems biology" for the research of TCM prescription to reveal the pharma-material basis and action mechanism and the compatibility scientific connotation, with a prescription Yinchenhao Tang as a case study. PMID:24494574

  6. Offshore liquified gas transfer system

    SciTech Connect

    Karl, R.D.

    1982-02-16

    A hose assembly is described for use in the transference of cooled liquified gas to a vessel, in a system that requires the flexible hose to lie in the water. The hose assembly includes a flexible inner hose forming a central passage through which liquified gas can pass towards the vessel and having walls that are permeable to the bleeding of vapor therethrough, to avoid damage by expanding liquid droplets that find their way into the inner hose wall. The assembly also includes an outer hose with substantially impermeable walls, the outer hose surrounding the inner hose and leaving an annular passage between them which can receive the vapor permeating the inner hose. The annular passage also can be used to carry vapor from the vessel back to a shorebased installation which reliquifies it.

  7. Granisetron Transdermal System for Treatment of Symptoms of Gastroparesis: A Prescription Registry Study

    PubMed Central

    Midani, Deena; Parkman, Henry P

    2016-01-01

    Background/Aims Serotonin receptor (eg, 5-HT3) antagonists are used to treat nausea and vomiting from a variety of causes. Granisetron transdermal system (GTS) is an appealing delivery system for patients with gastroparesis. To assess if GTS improves nausea and vomiting and other gastroparesis symptoms in patients with gastroparesis. Methods Patients with gastroparesis and symptoms of nausea and vomiting refractory to conventional treatment were treated with GTS. Symptoms of gastroparesis were assessed using a modified Gastroparesis Cardinal Symptom Index (GCSI). Following 2 weeks of treatment, patients were asked to assess their symptoms and indicate their therapeutic response using the Clinical Patient Grading Assessment Scale (CPGAS) reporting if symptoms of nausea and vomiting improved on a scale: 0 = no change to +7 = completely better. Results Fifty-one patients received GTS by prescription: average age was 40 ± 17 years, 44 female, 11 diabetics, 23 ± 20% retention at 4 hours on gastric emptying scintigraphy. Thirty-nine of the 51 (76%) patients stated improvement with GTS. There was significant improvement in nausea and vomiting as assessed with CPGAS at 2 weeks (2.28 ± 2.53; P < 0.05). Symptoms of nausea and vomiting significantly improved. Other symptoms including postprandial fullness, loss of appetite, upper abdominal pain, and early satiety improved. Side effects reported included redness at the site of the patch in 7 patients, pruritus in 5, and constipation in 5. Conclusions GTS was moderately effective in reducing nausea and/or vomiting in 76% of gastroparesis patients. In addition to nausea and vomiting, symptoms of postprandial fullness, loss of appetite, upper abdominal pain, and early satiety also improved. PMID:27400689

  8. Prescriptions and Insurance Plans

    MedlinePlus

    MENU Return to Web version Prescriptions and Insurance Plans Prescriptions and Insurance Plans Getting a prescription filled is usually easy. But because of the high cost of prescription medicines, most insurance ...

  9. Transfer function characteristics of super resolving systems

    NASA Technical Reports Server (NTRS)

    Milster, Tom D.; Curtis, Craig H.

    1992-01-01

    Signal quality in an optical storage device greatly depends on the optical system transfer function used to write and read data patterns. The problem is similar to analysis of scanning optical microscopes. Hopkins and Braat have analyzed write-once-read-many (WORM) optical data storage devices. Herein, transfer function analysis of magnetooptic (MO) data storage devices is discussed with respect to improving transfer-function characteristics. Several authors have described improving the transfer function as super resolution. However, none have thoroughly analyzed the MO optical system and effects of the medium. Both the optical system transfer function and effects of the medium of this development are discussed.

  10. Dry Transfer Systems for Used Nuclear Fuel

    SciTech Connect

    Brett W. Carlsen; Michaele BradyRaap

    2012-05-01

    The potential need for a dry transfer system (DTS) to enable retrieval of used nuclear fuel (UNF) for inspection or repackaging will increase as the duration and quantity of fuel in dry storage increases. This report explores the uses for a DTS, identifies associated general functional requirements, and reviews existing and proposed systems that currently perform dry fuel transfers. The focus of this paper is on the need for a DTS to enable transfer of bare fuel assemblies. Dry transfer systems for UNF canisters are currently available and in use for transferring loaded canisters between the drying station and storage and transportation casks.

  11. [Co-payment on prescription drugs in the Spanish public health system: Certainty, risk and selection of risks].

    PubMed

    Simó Miñana, Juan

    2015-12-01

    The model of co-payment on prescription drugs in the Spanish National Health System (NHS) changed on 1 July 2012. For more than three decades that it was not modified. This article provides a brief historical reminder of the evolution of this model of co-payment. The basic characteristics of this model are compared with the model of copayment on prescription drugs of the Administrative Mutualism (Civil Servants). The document provides detailed information on the percentage of effective copayment, fundraising effects, the economic participation of the patient, among others, in both models. Finally, listed pending improvements not addressed by 2012 changes such as the concentration of the co-payment in the active patient population and risk selection promoted by the differences in the financial contribution between the two models of co-payment (NHS and Mutualist).

  12. Development of a Web-Based Clinical Decision Support System for Drug Prescription: Non-Interventional Naturalistic Description of the Antipsychotic Prescription Patterns in 4345 Outpatients and Future Applications

    PubMed Central

    Berrouiguet, Sofian; Barrigón, Maria Luisa; Brandt, Sara A.; Ovejero-García, Santiago; Álvarez-García, Raquel; Carballo, Juan Jose; Lenca, Philippe; Courtet, Philippe; Baca-García, Enrique

    2016-01-01

    Purpose The emergence of electronic prescribing devices with clinical decision support systems (CDSS) is able to significantly improve management pharmacological treatments. We developed a web application available on smartphones in order to help clinicians monitor prescription and further propose CDSS. Method A web application (www.MEmind.net) was developed to assess patients and collect data regarding gender, age, diagnosis and treatment. We analyzed antipsychotic prescriptions in 4345 patients attended in five Psychiatric Community Mental Health Centers from June 2014 to October 2014. The web-application reported average daily dose prescribed for antipsychotics, prescribed daily dose (PDD), and the PDD to defined daily dose (DDD) ratio. Results The MEmind web-application reported that antipsychotics were used in 1116 patients out of the total sample, mostly in 486 (44%) patients with schizophrenia related disorders but also in other diagnoses. Second generation antipsychotics (quetiapine, aripiprazole and long-acting paliperidone) were preferably employed. Low doses were more frequently used than high doses. Long acting paliperidone and ziprasidone however, were the only two antipsychotics used at excessive dosing. Antipsychotic polypharmacy was used in 287 (26%) patients with classic depot drugs, clotiapine, amisulpride and clozapine. Conclusions In this study we describe the first step of the development of a web application that is able to make polypharmacy, high dose usage and off label usage of antipsychotics visible to clinicians. Current development of the MEmind web application may help to improve prescription security via momentary feedback of prescription and clinical decision support system. PMID:27764107

  13. Meeting user needs in national healthcare systems: lessons from early adopter community pharmacists using the electronic prescriptions service

    PubMed Central

    2014-01-01

    Background The Electronic Prescription Service release Two (EPS2) is a new national healthcare information and communication technology in England that aims to deliver effective prescription writing, dispensing and reimbursement service to benefit patients. The aim of the study was to explore initial user experiences of Community Pharmacists (CPs) using EPS2. Methods We conducted nonparticipant observations and interviews in eight EPS2 early adopter community pharmacies classified as ‘first-of-type’ in midlands and northern regions in England. We interviewed eight pharmacists and two dispensers in addition to 56 hours recorded nonparticipant observations as field notes. Line-by-line coding and thematic analysis was conducted on the interview transcripts and field notes. Results CPs faced two types of challenge. The first was to do with missing electronic prescriptions. This was sometimes very disrupting to work practice, but pharmacists considered it a temporary issue resolvable with minor modifications to the system and user familiarity. The second was to do with long term design-specific issues. Pharmacists could only overcome these by using the system in ways not intended by the developers. Some felt that these issues would not exist had ‘real’ users been involved in the initial development. The issues were: 1) printing out electronic prescriptions (tokens) to dispense from for safe dispensing practices and to free up monitors for other uses, 2) logging all dispensing activities with one user’s Smartcard for convenience and use all human resources in the pharmacy, and, 3) problematic interface causing issues with endorsing prescriptions and claiming reimbursements. Conclusions We question if these unintended uses and barriers would have occurred had a more rigorous user-centric principles been applied at the earlier stages of design and implementation of EPS. We conclude that, since modification can occur at the evaluation stage, there is still scope

  14. A prescription fraud detection model.

    PubMed

    Aral, Karca Duru; Güvenir, Halil Altay; Sabuncuoğlu, Ihsan; Akar, Ahmet Ruchan

    2012-04-01

    Prescription fraud is a main problem that causes substantial monetary loss in health care systems. We aimed to develop a model for detecting cases of prescription fraud and test it on real world data from a large multi-center medical prescription database. Conventionally, prescription fraud detection is conducted on random samples by human experts. However, the samples might be misleading and manual detection is costly. We propose a novel distance based on data-mining approach for assessing the fraudulent risk of prescriptions regarding cross-features. Final tests have been conducted on adult cardiac surgery database. The results obtained from experiments reveal that the proposed model works considerably well with a true positive rate of 77.4% and a false positive rate of 6% for the fraudulent medical prescriptions. The proposed model has the potential advantages including on-line risk prediction for prescription fraud, off-line analysis of high-risk prescriptions by human experts, and self-learning ability by regular updates of the integrative data sets. We conclude that incorporating such a system in health authorities, social security agencies and insurance companies would improve efficiency of internal review to ensure compliance with the law, and radically decrease human-expert auditing costs.

  15. Saturn facility oil transfer automation system

    SciTech Connect

    Joseph, Nathan R.; Thomas, Rayburn Dean; Lewis, Barbara Ann; Malagon, Hector M.

    2014-02-01

    The Saturn accelerator, owned by Sandia National Laboratories, has been in operation since the early 1980s and still has many of the original systems. A critical legacy system is the oil transfer system which transfers 250,000 gallons of transformer oil from outside storage tanks to the Saturn facility. The oil transfer system was iden- ti ed for upgrade to current technology standards. Using the existing valves, pumps, and relay controls, the system was automated using the National Instruments cRIO FGPA platform. Engineered safety practices, including a failure mode e ects analysis, were used to develop error handling requirements. The uniqueness of the Saturn Oil Automated Transfer System (SOATS) is in the graphical user interface. The SOATS uses an HTML interface to communicate to the cRIO, creating a platform independent control system. The SOATS was commissioned in April 2013.

  16. Charge transfer mechanism in nonstationary granular systems

    NASA Astrophysics Data System (ADS)

    Ioselevich, A. S.; Sivak, V. V.

    2015-12-01

    We consider a nonstationary array of conductors, connected by resistances that fluctuate with time. The charge transfer between a particular pair of conductors is supposed to be dominated by electrical breakdowns—the moments when the corresponding resistance is close to zero. An amount of charge, transferred during a particular breakdown, is controlled by the condition of minimum for the electrostatic energy of the system. We find the conductivity, relaxation rate, and fluctuations for such a system within the classical approximation, valid, if the typical transferred charge is large compared to e . We discuss possible realizations of the model for colloidal systems and arrays of polymer-linked grains.

  17. Optical Energy Transfer and Conversion System

    NASA Technical Reports Server (NTRS)

    Stone, William C. (Inventor); Hogan, Bartholomew P. (Inventor)

    2015-01-01

    An optical power transfer system comprising a fiber spooler, a fiber optic rotary joint mechanically connected to the fiber spooler, and an electrical power extraction subsystem connected to the fiber optic rotary joint with an optical waveguide. Optical energy is generated at and transferred from a base station through fiber wrapped around the spooler, through the rotary joint, and ultimately to the power extraction system at a remote mobility platform for conversion to another form of energy.

  18. Electric power distribution and load transfer system

    NASA Technical Reports Server (NTRS)

    Bradford, Michael P. (Inventor); Parkinson, Gerald W. (Inventor); Grant, Ross M. (Inventor)

    1989-01-01

    A power distribution system includes a plurality of power sources and load transfer units including transistors and diodes connected in series and leading to a common power output, each of the transistors being controller switchable subject to voltage levels of the respective input and output sides of said transistors, and the voltage and current level of said common power output. The system is part of an interconnection scheme in which all but one of the power sources is connected to a single load transfer unit, enabling the survival of at least a single power source with the failure of one of the load transfer units.

  19. Electric power distribution and load transfer system

    NASA Technical Reports Server (NTRS)

    Bradford, Michael P. (Inventor); Parkinson, Gerald W. (Inventor); Grant, Ross M. (Inventor)

    1987-01-01

    A power distribution system includes a plurality of power sources and load transfer units including transistors and diodes connected in series and leading to a common power output, each of the transistors being controller switchable subject to voltage levels of the respective input and output sides of said transistors, and the voltage and current level of said common power output. The system is part of an interconnection scheme in which all but one of the power sources is connected to a single load transfer unit, enabling the survival of at least a single power source with the failure of one of the load transfer units.

  20. Fuel metering and transfer control system

    SciTech Connect

    Mathieson, R.W.

    1980-10-14

    An auxiliary fuel metering and transfer control system for an internal combustion engine is described. The system consists essentially of a pressure vessel for storage of propane, methane, natural gas or a similar gaseous fuel, a pressure regulator for maintaining constant gaseous fuel pressure during operation of the system, a solenoid valve and a magnetic reset safety switch, a metering valve, a transfer valve and an auxiliary fuel nozzle positioned in the venturi of the carburetor on the engine using the system. The metering valve operates in response to changes in the intake manifold vacuum of the engine and changes in the air velocity in the carburetor of the engine. The transfer valve operates in response to movement of the throttle linkage on the carburetor of the engine. During operation of the engine, the system is substituted for both the idle circuit or system and the acceleration circuit or system of the carburetor.

  1. Synchronous transfer circuits for redundant systems

    NASA Technical Reports Server (NTRS)

    Nagano, S.

    1978-01-01

    Circuit arrangements for flip-flops, counters, and clock drivers in redundant systems ensure that control is synchronously transferred to surviving components when failure occurs. In addition to original application to spacecraft systems, redundant circuits have terrestrial uses in power generators, solar-energy converters, computers, vehicle controllers, and other systems demanding high reliability.

  2. Microwork transfer system in a nanomanufacturing world

    NASA Astrophysics Data System (ADS)

    Tsuchiya, Kensuke; Nakao, Masayuki; Okusa, Takenori; Hatamura, Yotaro; Matsumoto, Kiyoshi

    1998-01-01

    Practical micromachines, such as magnetic heads or endoscopic tools, can not be made only by shaping processes; they require post-machining processes such as assembling, wiring, piping, etc. The authors have developed an integrated manufacturing system, 'nano manufacturing world' (NMW). It performs shaping, post-machining or transferring like a factory. In this paper, we introduce a microwork transfer system, which functions a) steady transfer of a workpiece, b) non-release chucking of the workpiece during production and c) individual rotation of the workpiece using a preloaded microslide bearing on the pallet. Developed transfer system could realize the functions: less positioning error due to accurate pallet positioning by taper pins, high transfer yield of the workpieces due to no missing by a micro chuck, sub-micron rotational fluctuation due to a roller pallet by a preloaded micro slide bearing. Through the fabrication demonstrations of a sub-1 mm3 micro-house or micro force sensor block of 125 X 100 X 500 micrometers , it has been confirmed that this transfer system improved the performance of integrated manufacturing in NMW.

  3. Dichotomy in the definition of prescriptive information suggests both prescribed data and prescribed algorithms: biosemiotics applications in genomic systems

    PubMed Central

    2012-01-01

    The fields of molecular biology and computer science have cooperated over recent years to create a synergy between the cybernetic and biosemiotic relationship found in cellular genomics to that of information and language found in computational systems. Biological information frequently manifests its "meaning" through instruction or actual production of formal bio-function. Such information is called Prescriptive Information (PI). PI programs organize and execute a prescribed set of choices. Closer examination of this term in cellular systems has led to a dichotomy in its definition suggesting both prescribed data and prescribed algorithms are constituents of PI. This paper looks at this dichotomy as expressed in both the genetic code and in the central dogma of protein synthesis. An example of a genetic algorithm is modeled after the ribosome, and an examination of the protein synthesis process is used to differentiate PI data from PI algorithms. PMID:22413926

  4. Solid target irradiation and transfer system

    NASA Astrophysics Data System (ADS)

    Gelbart, W.; Johnson, R. R.; Abeysekera, B.

    2012-12-01

    A compact, fully automated solid target irradiation, handling and transfer system was developed for the 100Mo/99m Tc production; however, it can be used for any solid target material. All the target handling is fully automated. The target is pneumatically transferred to the irradiation station where it is removed from the carrier, placed in the irradiation chamber and the cooling water connected. At the end of irradiation the target is returned to the carrier and transferred to the processing hot cell where it is automatically placed in a distillation unit. 100 Mo targets are prepared by plasma spraying or laser cladding of the copper target.

  5. Design Criteria for Bagless Transfer System (BTS) Packaging System

    SciTech Connect

    RISENMAY, H.R.

    2000-04-26

    This document provides the criteria for the design and installation of a Bagless Transfer System (BTS); Blend, Sieve and Balance Equipment; and Supercritical Fluid Extraction System (SFE). The project consists of 3 major modules: (1) Bagless Transfer System (BTS) Module; (2) Blend, Sieve and Balance Equipment; and (3) Supercritical Fluid Extraction (SFE) Module.

  6. Transfer Function Control for Biometric Monitoring System

    NASA Technical Reports Server (NTRS)

    Chmiel, Alan J. (Inventor); Humphreys, Bradley T. (Inventor); Grodinsky, Carlos M. (Inventor)

    2015-01-01

    A modular apparatus for acquiring biometric data may include circuitry operative to receive an input signal indicative of a biometric condition, the circuitry being configured to process the input signal according to a transfer function thereof and to provide a corresponding processed input signal. A controller is configured to provide at least one control signal to the circuitry to programmatically modify the transfer function of the modular system to facilitate acquisition of the biometric data.

  7. Transfer system worked in rough conditions

    SciTech Connect

    Not Available

    1985-05-01

    A transfer system using a small waterplane area twin hull vessel (SWATH) and high-wire rigging has been developed by Rauma-Repola of Rauma, Finland as an alternative to helicopter movement of personnel and light cargo in the North Sea. The SWATH is used because it has better seakeeping characteristics than regular supply boats. With the large number of platform workers transported in such a vessel, the developers contend there are now sufficient platforms to make such transfer systems economic. The system, a modification of one used between ships at sea since 1969, is described.

  8. Characterization of Adolescent Prescription Drug Abuse and Misuse Using the Researched Abuse Diversion and Addiction-Related Surveillance (RADARS[R]) System

    ERIC Educational Resources Information Center

    Zosel, Amy; Bartelson, Becki Bucher; Bailey, Elise; Lowenstein, Steven; Dart, Rick

    2013-01-01

    Objective: To describe the characteristics and health effects of adolescent (age 13-19 years) prescription drug abuse and misuse using the Researched Abuse Diversion and Addiction-Related Surveillance (RADARS[R])) System. Method: Secondary analysis of data collected from RADARS System participating poison centers was performed. Data for all…

  9. Electric orbit transfer vehicle cryogenic propellant system

    NASA Astrophysics Data System (ADS)

    Schuster, J. R.; Huynh, C. T.; Williams, G. E.

    An electric orbit transfer vehicle (EOTV) is intended to transfer payloads from low Earth orbit (LEO) to higher orbits using low-thrust solar-electric propulsion and hydrogen propellant. Because of its high specific impulse and synergistic sharing of power supply, attitude control and communication systems with the payload, the highly efficient EOTV transfer stage permits use of a smaller, less costly launch vehicle than if orbit transfer were accomplished using chemical propulsion. Study of the propellant storage and supply system for an EOTV intended to fly a 168 day spiral trajectory from LEO to geosynchronous orbit (GEO) reveals that the low propellant flow rate needed by the thrusters can be supplied by the boil-off from the storage tank, eliminating the need for any overboard venting. The tank can be fabricated under the same pressure-stabilized, thin, stainless steel monocoque construction as the current Centaur upper stage, and insulated with Centaur fixed foam and MLI. The tank contains a thermodynamic vent system (TVS) for control of tank pressure in zero and low gravity and for supply of propellant to the thrusters. An external compressor, accumulator and regulator condition the hydrogen boil-off provided by the TVS and provide for start-up and shut-down transients. The resulting system is simple, has a very low structural mass fraction and builds on the Centaur cryogenic upper stage technology, which has been operational for over 25 years.

  10. Promoting Transfer by Grounding Complex Systems Principles

    ERIC Educational Resources Information Center

    Goldstone, Robert L.; Wilensky, Uri

    2008-01-01

    Understanding scientific phenomena in terms of complex systems principles is both scientifically and pedagogically important. Situations from different disciplines of science are often governed by the same principle, and so promoting knowledge transfer across disciplines makes valuable cross-fertilization and scientific unification possible.…

  11. System Transfer, Education, and Development in Mozambique

    ERIC Educational Resources Information Center

    Cossa, Jose

    2011-01-01

    In this study the author used conceptual historical method to assess the phenomenon of system transfer and the association between education and development in Mozambique. The assessment was administered through critical analysis of documents pertaining to the Salazar (1924-1966), Machel (1975-1986), and Chissano (1986-2005) administrations. The…

  12. Acquisition systems for heat transfer measurement

    SciTech Connect

    De Witt, R.J.

    1983-01-01

    Practical heat transfer data acquisition systems are normally characterized by the need for high-resolution, low-drift, low-speed recording devices. Analog devices such as strip chart or circular recorders and FM analog magnetic tape have excellent resolution and work well when data will be presented in temperature versus time format only and need not be processed further. Digital systems are more complex and require an understanding of the following components: digitizing devices, interface bus types, processor requirements, and software design. This paper discusses all the above components of analog and digital data acquisition, as they are used in current practice. Additional information on thermocouple system analysis will aid the user in developing accurate heat transfer measuring systems.

  13. Satellite system considerations for computer data transfer

    NASA Technical Reports Server (NTRS)

    Cook, W. L.; Kaul, A. K.

    1975-01-01

    Communications satellites will play a key role in the transmission of computer generated data through nationwide networks. This paper examines critical aspects of satellite system design as they relate to the computer data transfer task. In addition, it discusses the factors influencing the choice of error control technique, modulation scheme, multiple-access mode, and satellite beam configuration based on an evaluation of system requirements for a broad range of application areas including telemetry, terminal dialog, and bulk data transmission.

  14. Prescription Drug Abuse

    MedlinePlus

    ... what the doctor prescribed, it is called prescription drug abuse. It could be Taking a medicine that ... purpose, such as getting high Abusing some prescription drugs can lead to addiction. These include narcotic painkillers, ...

  15. Treating Prescription Drug Addiction

    MedlinePlus

    ... Trends and Alerts Alcohol Club Drugs Cocaine Hallucinogens Heroin Inhalants Marijuana MDMA (Ecstasy/Molly) Methamphetamine Opioids Prescription ... View all ​Research Reports Opioids: The Prescription Drug & Heroin Overdose Epidemic (HHS website) NIDA Home Site Map ...

  16. Forest Resource Information System. Phase 3: System transfer report

    NASA Technical Reports Server (NTRS)

    Mroczynski, R. P. (Principal Investigator)

    1981-01-01

    Transfer of the forest reserve information system (FRIS) from the Laboratory for Applications of Remote Sensing to St. Regis Paper Company is described. Modifications required for the transfer of the LARYS image processing software are discussed. The reformatting, geometric correction, image registration, and documentation performed for preprocessing transfer are described. Data turnaround was improved and geometrically corrected and ground-registered CCT LANDSAT 3 data provided to the user. The technology transfer activities are summarized. An application test performed in order to assess a Florida land acquisition is described. A benefit/cost analysis of FRIS is presented.

  17. Phase transfer function of digital imaging systems

    NASA Astrophysics Data System (ADS)

    Bhakta, Vikrant R.

    For the past several decades, optical engineering has relied heavily on Fourier analysis of linear systems as a valuable aid in realizing numerous imaging applications. Today, spatial frequency analysis via the optical transfer function (OTF) remains an integral tool for the design, characterization and testing of incoherent imaging systems. The magnitude of the complex OTF is known as the modulation transfer function (MTF) and its phase is given by the phase transfer function (PTF). The MTF represents the contrast reduction at each spatial frequency; whereas, the PTF represents the spatial shift of these frequencies. While the MTF has been used extensively to characterize imaging systems, the PTF has long been ignored because it was thought to have an insignificant presence and to be difficult to understand and measure. Through theoretical analysis and experimental demonstrations, this work addresses all of these issues and shows that the PTF is a valuable tool for modern-day digital imaging systems. The effects of optical aberrations on the PTF of an imaging system in the absence of aliasing have been analyzed in detail. However, for the digital imaging systems, the effect of aliasing on the overall system behavior becomes an important consideration. To this end, the effects of aliasing on the PTF of the sampled imaging system are described and its key properties are derived. The role of PTF as an essential metric in today's imaging systems necessitates practical PTF measurement techniques. Two, easy-to-implement, image-based methods for PTF measurement are described and experimentally validated. These measurement methods and the insights gained from the theoretical analysis are leveraged for several applications spanning diverse fields such as optical system characterization, computational imaging, and image processing.

  18. A new transfer system for solid targets

    NASA Astrophysics Data System (ADS)

    Klug, J.; Buckley, K. R.; Zeisler, S. K.; Dodd, M.; Tsao, P.; Hoehr, C.; Economou, C.; Corsaut, J.; Appiah, J. P.; Kovacs, M. S.; Valliant, J. F.; Benard, F.; Ruth, T. J.; Schaffer, P.

    2012-12-01

    As part of a collaborative research project funded by Natural Resources Canada, TRIUMF has designed and manufactured solid target and solid target processing systems for the production of technetium-99m using small medical cyclotrons. The system described herein is capable of transporting the target from a hotcell, where the target is loaded and processed, to the cyclotron and back again. The versatility of the transfer system was demonstrated through the successful installation and operation on the ACSI TR 19 at the BC Cancer Agency, the GE PETtrace cyclotrons at Lawson Health Research (LHRI) and the Centre for Probe Development and Commercialization (CDPC).

  19. Advanced orbit transfer vehicle propulsion system study

    NASA Technical Reports Server (NTRS)

    Cathcart, J. A.; Cooper, T. W.; Corringrato, R. M.; Cronau, S. T.; Forgie, S. C.; Harder, M. J.; Mcallister, J. G.; Rudman, T. J.; Stoneback, V. W.

    1985-01-01

    A reuseable orbit transfer vehicle concept was defined and subsequent recommendations for the design criteria of an advanced LO2/LH2 engine were presented. The major characteristics of the vehicle preliminary design include a low lift to drag aerocapture capability, main propulsion system failure criteria of fail operational/fail safe, and either two main engines with an attitude control system for backup or three main engines to meet the failure criteria. A maintenance and servicing approach was also established for the advanced vehicle and engine concepts. Design tradeoff study conclusions were based on the consideration of reliability, performance, life cycle costs, and mission flexibility.

  20. System-focused environmental flow regime prescription, monitoring and adaptive management

    NASA Astrophysics Data System (ADS)

    Hetherington, David; Lexartza Artza, Irantzu

    2016-04-01

    The definition of appropriate environmental flow regimes through hydropower schemes and water storage reservoirs is key part of mitigation. Insufficient (magnitude and variability) environmental flows can result in much environmental harm with negative impacts being encountered by morphological, ecological and societal systems. Conventionally, environmental flow regimes have been determined by using generic protocols and guidance such as the Tennant method of environmental flow estimation. It is generally accepted that such approaches to minimum environmental flow definition, although being a useful starting point, are not universally applicable across catchment typologies and climatic regions. Such approaches will not always produce conditions that would be associated with 'Good Ecological Status' under the Water framework Directive (or equivalent). Other similar approaches to minimum environmental flow estimation are used that are specific to geographies, yet still the associated guidance rarely thoroughly covers appropriate definition for healthy holistic systems across the flow regime. This paper draws on experience of system-focused environmental flow regime determination in the UK and the Georgian Caucasus Mountains, which allowed for a critical analysis of more conventional methods to be undertaken. The paper describes a recommended approach for determining appropriate environmental flow regimes based on analysis of the impacted geomorphological, ecological and societal systems in a way which is sensitive to the local holistic environment and associated complexities and interactions. The paper suggests that a strong understanding of the local geomorphology in key in predicting how flows will manifest habitat differently across the flow regime, and be spatially dynamic. Additionally, an understanding of the geomorphological system allows the flow of course and fine sediment to be factored into the initial suggested environmental flow regime. It is suggested

  1. Long range inductive power transfer system

    NASA Astrophysics Data System (ADS)

    Lawson, James; Pinuela, Manuel; Yates, David C.; Lucyszyn, Stepan; Mitcheson, Paul D.

    2013-12-01

    We report upon a recently developed long range inductive power transfer system (IPT) designed to power remote sensors with mW level power consumption at distances up to 7 m. In this paper an inductive link is established between a large planar (1 × 1 m) transmit coil (Tx) and a small planer (170 × 170 mm) receiver coil (Rx), demonstrating the viability of highly asymmetrical coil configurations that real-world applications such as sensor networks impose. High Q factor Tx and Rx coils required for viable power transfer efficiencies over such distances are measured using a resonant method. The applicability of the Class-E amplifier in very low magnetic coupling scenarios and at the high frequencies of operation required for high Q operation is demonstrated by its usage as the Tx coil driver.

  2. Submersible pumping system with heat transfer mechanism

    SciTech Connect

    Hunt, Daniel Francis Alan; Prenger, F. Coyne; Hill, Dallas D; Jankowski, Todd Andrew

    2014-04-15

    A submersible pumping system for downhole use in extracting fluids containing hydrocarbons from a well. In one embodiment, the pumping system comprises a rotary induction motor, a motor casing, one or more pump stages, and a cooling system. The rotary induction motor rotates a shaft about a longitudinal axis of rotation. The motor casing houses the rotary induction motor such that the rotary induction motor is held in fluid isolation from the fluid being extracted. The pump stages are attached to the shaft outside of the motor casing, and are configured to impart fluid being extracted from the well with an increased pressure. The cooling system is disposed at least partially within the motor casing, and transfers heat generated by operation of the rotary induction motor out of the motor casing.

  3. [Drugs prescription for osteoporosis].

    PubMed

    Erviti, J

    2003-01-01

    The aim of this study is to analyse the evolution of the global and relative use of medicines recommended for osteoporosis during the period between 1998 and 2002 in Navarra, and their adaptation to present evidence, making reference to the differences in the prescription profile in primary and specialised care. To this end, information is used from all the prescriptions made within the National Health System where one of these medicines is recommended, issued in pharmacies of Navarra, and billed to the Navarra Health Service-Osasunbidea. The profile of the use of medicines in osteoporosis differs significantly depending on the type of specialist who prescribes them. It would be useful to homogenise the approach to the prevention of bone fractures. In the period under study the use of medicines in Navarra rose by some 85.6% in number of dose/1,000 inhabitants/day. The relative use of hormone replacement therapy fell constantly, the employment of calcitonins remained steady, undergoing a cyclical profile of peaks in winter and valleys in summer, while the relative use of biphosphonates and raloxifen tended to increase. There is a need to evaluate the results on health of the use of these medicines in clinical practice given the discreet efficacy results obtained in clinical trials. Use of calcium should be encouraged because of its potential in the prevention of hip fractures against the rest of the medicinal alternatives. The relative use of raloxifen and calcitonins seems excessive.

  4. Bagless Transfer System Welder Analysis Software

    SciTech Connect

    Collins, Susan L.

    2003-10-01

    The Bagless Transfer System Welder Analysis Software (BTS WAS) was developed by SRTC for use with the Bagless Transfer System. During the welding process, critical weld parameters such as weld current and voltage, can give valuable informaitoin about the weld. In the past, weld data from the TIG welding process, such as the bagless transfer system in FB-Line, has been monitored using strip chart recorders. The data from the weld process, recorded on the strip chart recorder traces, were reviewed by the supervisor using a procedure and criteria to analyze the weld. This hand checking can be tedious and time consuming. To improve this process, another software package developed by SRTC, the BTS DAS, digitizes the weld data and stores the weld data in a file. The BTS WAS automates the weld analysis process by analyzing the data obtained during the weld process against the same weld criteria that the supervisor currently users. Of course with the automated analysis system the supervisor is still provided the same information in the same chart display format so he can also manually review the data as desired. The BTS WAS reads in a data file that was prevously collected using the BTS DAS software. The software will read the file and parse the data. The user is first prompted to enter the file name. The file is then opened and the operator name and Date/Time of Acquisition are read from the file and displayed on the screen. The binary weld data is then read from the file into an array until the end of the file is reached. The shunt and weld current, voltage, RPM, and position data are displayed on the screen in graphical formats on the front panel. The weld power and resistance are calculated and are also displayed in graphical format on the front panel. Individual tack analysis data is provided for each of the three tacks. The main weld and downslope data is also displayed.

  5. Oxygen Transfer Characteristics of Miniaturized Bioreactor Systems

    PubMed Central

    Kirk, Timothy V; Szita, Nicolas

    2013-01-01

    Since their introduction in 2001 miniaturized bioreactor systems have made great advances in function and performance. In this article the dissolved oxygen (DO) transfer performance of submilliliter microbioreactors, and 1–10 mL minibioreactors was examined. Microbioreactors have reached kLa values of 460 h-1, and are offering instrumentation and some functionality comparable to production systems, but at high throughput screening volumes. Minibioreactors, aside from one 1,440 h-1 kLa system, have not offered as high rates of DO transfer, but have demonstrated superior integration with automated fluid handling systems. Microbioreactors have been typically limited to studies with E. coli, while minibioreactors have offered greater versatility in this regard. Further, mathematical relationships confirming the applicability of kLa measurements across all scales have been derived, and alternatives to fluorescence lifetime DO sensors have been evaluated. Finally, the influence on reactor performance of oxygen uptake rate (OUR), and the possibility of its real-time measurement have been explored. Biotechnol. Bioeng. 2013; 110: 1005–1019. © 2012 Wiley Periodicals, Inc. PMID:23280578

  6. Expertise transfer for expert system design

    SciTech Connect

    Boose, J.H.

    1986-01-01

    This book is about the Expertise Transfer System-a computer program which interviews experts and helps them build expert systems, i.e. computer programs that use knowledge from experts to make decisions and judgements under conditions of uncertainty. The techniques are useful to anyone who uses decision-making information based on the expertise of others. The methods can also be applied to personal decision-making. The interviewing methodology is borrowed from a branch of psychology called Personal Construct Theory. It is not necessary to use a computer to take advantage of the techniques from Personal Construction Theory; the fundamental procedures used by the Expertise Transfer System can be performed using paper and pencil. It is not necessary that the reader understand very much about computers to understand the ideas in this book. The few relevant concepts from computer science and expert systems that are needed are explained in a straightforward manner. Ideas from Personal Construct Psychology are also introduced as needed.

  7. Value-based leadership. A prescription for reforming the American health care system.

    PubMed

    Cross, L A

    1997-01-01

    Many reforms have been suggested for health care in the last 30 years yet they are mainly treating symptoms rather than getting at the root cause of the problems. The underlying problem is a lack of vision for the health care system. There is no comprehensive, uniform vision of American medicine rooted in the needs of our society. This vision should be based on the values that significantly challenge physicians: patient satisfaction, patient empowerment, cost effectiveness and the appropriate use of resources, patent access, and continuous quality improvement based on appropriate data techniques.

  8. Measuring the In-Process Figure, Final Prescription, and System Alignment of Large Optics and Segmented Mirrors Using Lidar Metrology

    NASA Technical Reports Server (NTRS)

    Ohl, Raymond; Slotwinski, Anthony; Eegholm, Bente; Saif, Babak

    2011-01-01

    The fabrication of large optics is traditionally a slow process, and fabrication capability is often limited by measurement capability. W hile techniques exist to measure mirror figure with nanometer precis ion, measurements of large-mirror prescription are typically limited to submillimeter accuracy. Using a lidar instrument enables one to measure the optical surface rough figure and prescription in virtuall y all phases of fabrication without moving the mirror from its polis hing setup. This technology improves the uncertainty of mirror presc ription measurement to the micron-regime.

  9. Satellite services system analysis study: Propellant transfer system

    NASA Technical Reports Server (NTRS)

    1982-01-01

    General servicing requirements, a servicing mission concept and scenario, overall servicing needs, basic servicing equipment, and a general servicing mission configuration layout are addressed. Servicing needs, equipment concepts, system requirements equipment specifications, preliminary designs, and resource requirements for flight hardware for the propellant transfer system are also addressed.

  10. Enabling the BC Transfer System: A Discussion Paper

    ERIC Educational Resources Information Center

    British Columbia Council on Admissions and Transfer, 2011

    2011-01-01

    This discussion paper outlines processes, as well as opportunities and constraints, for "enabling" BC Transfer System institutions to enhance transfer credit information in the BC Transfer Guide, making it more reflective of institutional practices and student mobility. BCCAT's focus is increasing the availability of transfer credit information…

  11. Recalibrating the BC Transfer System: Approved Final Report

    ERIC Educational Resources Information Center

    British Columbia Council on Admissions and Transfer, 2006

    2006-01-01

    In November 2005, the BC Council on Admissions and Transfer launched a consultation entitled Recalibrating the BC Transfer System with the institutional members of the BC Transfer System and other interested parties. This consultation was motivated in large part by significant changes in the BC post-secondary system over the last decade, and…

  12. Bagless Transfer System Welder Analysis Software

    2003-10-01

    The Bagless Transfer System Welder Analysis Software (BTS WAS) was developed by SRTC for use with the Bagless Transfer System. During the welding process, critical weld parameters such as weld current and voltage, can give valuable informaitoin about the weld. In the past, weld data from the TIG welding process, such as the bagless transfer system in FB-Line, has been monitored using strip chart recorders. The data from the weld process, recorded on the stripmore » chart recorder traces, were reviewed by the supervisor using a procedure and criteria to analyze the weld. This hand checking can be tedious and time consuming. To improve this process, another software package developed by SRTC, the BTS DAS, digitizes the weld data and stores the weld data in a file. The BTS WAS automates the weld analysis process by analyzing the data obtained during the weld process against the same weld criteria that the supervisor currently users. Of course with the automated analysis system the supervisor is still provided the same information in the same chart display format so he can also manually review the data as desired. The BTS WAS reads in a data file that was prevously collected using the BTS DAS software. The software will read the file and parse the data. The user is first prompted to enter the file name. The file is then opened and the operator name and Date/Time of Acquisition are read from the file and displayed on the screen. The binary weld data is then read from the file into an array until the end of the file is reached. The shunt and weld current, voltage, RPM, and position data are displayed on the screen in graphical formats on the front panel. The weld power and resistance are calculated and are also displayed in graphical format on the front panel. Individual tack analysis data is provided for each of the three tacks. The main weld and downslope data is also displayed.« less

  13. Revisiting "the origins of compulsory drug prescriptions".

    PubMed Central

    Marks, H M

    1995-01-01

    It has been argued that today's prescription drug market originated in the arbitrary acts of the US Food and Drug Administration (FDA), which in 1938 issued regulations creating a class of drugs that could be sold by prescription only. On the basis of the FDA's administrative records, I argue that the 1938 regulations on prescription drug labeling were initiated by industry and then agreed to by the FDA; that contemporaries understood and accepted the reasons for restricting the use of certain drugs; and that the subsequent evolution of these regulations is best understood as an FDA effort to limit industry abuses of the prescription labeling system. This decade-long war of position ended when drug manufacturers persuaded the US Congress to enshrine their version of prescription labeling in law in a highly politicized struggle over government's role in the economy. Images FIGURE 1 PMID:7832245

  14. Prescription Drug Abuse

    ERIC Educational Resources Information Center

    Hamilton, Gloria J.

    2009-01-01

    This article presents current statistics on nonmedical use of both categories of prescription medications by high school and college students. The incidence of nonmedical use of prescription medications continues to increase among high school and college students. Two categories of drugs that are commonly used for reasons other than those for…

  15. Prescription Drugs and Cold Medicines

    MedlinePlus

    ... Abuse » Prescription Drugs & Cold Medicines Prescription Drugs & Cold Medicines Email Facebook Twitter What is Prescription Drug Abuse: ... treatment of addiction. Read more Safe Disposal of Medicines Disposal of Unused Medicines: What You Should Know ( ...

  16. HEAT TRANSFER AND TRITIUM PRODUCING SYSTEM

    DOEpatents

    Johnson, E.F.

    1962-06-01

    This invention related to a circulating lithium-containing blanket system in a neution source hav'ing a magnetic field associated therewith. The blanket serves simultaneously and efficiently as a heat transfer mediunm and as a source of tritium. The blanket is composed of a lithium-6-enriched fused salt selected from the group consisting of lithium nitrite, lithium nitrate, a mixture of said salts, a mixture of each of said salts with lithium oxide, and a mixture of said salts with each other and with lithium oxide. The moderator, which is contained within the blanket in a separate conduit, can be water. A stellarator is one of the neutron sources which can be used in this invention. (AEC)

  17. Infrared radiative energy transfer in gaseous systems

    NASA Technical Reports Server (NTRS)

    Tiwari, Surendra N.

    1991-01-01

    Analyses and numerical procedures are presented to investigate the radiative interactions in various energy transfer processes in gaseous systems. Both gray and non-gray radiative formulations for absorption and emission by molecular gases are presented. The gray gas formulations are based on the Planck mean absorption coefficient and the non-gray formulations are based on the wide band model correlations for molecular absorption. Various relations for the radiative flux and divergence of radiative flux are developed. These are useful for different flow conditions and physical problems. Specific plans for obtaining extensive results for different cases are presented. The procedure developed was applied to several realistic problems. Results of selected studies are presented.

  18. Bagless Transfer System Welder Data Acquisition Software

    SciTech Connect

    Collins, Susan L.

    2003-09-30

    The Bagless Transfer System Welder Data Acquisition Software (BTS DAS) was developed by SRTC to replace a strip chart recorder that has been in place since the design of the BTS. During the welding process, critical weld parameters such as weld current and voltage, can give valuable information about the weld. In the past, weld data from the TID welding process, has been monitored using strip chart recorders. The data from the weld process, recorded on the strip chart recorder traces, are reviewed to analyze the weld. The BTS DAS improves this technology by digitizing the weld data which allows for automation of the analysis process. Also, the data files are now stored digitally as well as a hard copy printout, so they can be reanalyzed if needed. The BTS DAS performs the necessary functions to perform the data acquisition functions during the BTS Welding Process. It is important to monitor the critical weld parameters, current and voltage, during a weld as they can be used to set acceptance criteria for weld acceptance. The software monitors and records the weld current, voltage, and RPM data. The welder DAS is a passive device and does not control the welder. The BTS control system interfaces directly with the welder and the BTS DAS. Digital handshaking is used between the BTS DAS and the BTS control system to ensure that the DAS is ready to weld prior to allowing the operator to initiate the welding process.

  19. Bagless Transfer System Welder Data Acquisition Software

    2003-09-30

    The Bagless Transfer System Welder Data Acquisition Software (BTS DAS) was developed by SRTC to replace a strip chart recorder that has been in place since the design of the BTS. During the welding process, critical weld parameters such as weld current and voltage, can give valuable information about the weld. In the past, weld data from the TID welding process, has been monitored using strip chart recorders. The data from the weld process, recordedmore » on the strip chart recorder traces, are reviewed to analyze the weld. The BTS DAS improves this technology by digitizing the weld data which allows for automation of the analysis process. Also, the data files are now stored digitally as well as a hard copy printout, so they can be reanalyzed if needed. The BTS DAS performs the necessary functions to perform the data acquisition functions during the BTS Welding Process. It is important to monitor the critical weld parameters, current and voltage, during a weld as they can be used to set acceptance criteria for weld acceptance. The software monitors and records the weld current, voltage, and RPM data. The welder DAS is a passive device and does not control the welder. The BTS control system interfaces directly with the welder and the BTS DAS. Digital handshaking is used between the BTS DAS and the BTS control system to ensure that the DAS is ready to weld prior to allowing the operator to initiate the welding process.« less

  20. Prescription diets for rabbits.

    PubMed

    Proença, Laila Maftoum; Mayer, Jörg

    2014-09-01

    Dietary management can be used with drug therapy for the successful treatment of many diseases. Therapeutic nutrition is well-recognized in dogs and cats and is beginning to increase among other pet species, including rabbits. The nutritional component of some rabbit diseases (eg, urolithiasis) is not completely understood, and the clinician should evaluate the use of prescription diets based on the scientific literature and individual needs. Long-term feeding trials are needed to further evaluate the efficacy of prescription diets in rabbits. Prescription diets are available for selected diseases in rabbits, including diets for immediate-term, short-term, and long-term management. PMID:25155667

  1. Space Biosensor Systems: Implications for Technology Transfer

    NASA Technical Reports Server (NTRS)

    Hines, J. W.; Somps, C. J.; Madou, M.; Imprescia, Clifford C. (Technical Monitor)

    1997-01-01

    To meet the need for continuous, automated monitoring of animal subjects, including; humans, during space flight, NASA is developing advanced physiologic sensor and biotelemetry system technologies. The ability to continuously track basic physiological parameters, such as heart rate, blood pH, and body temperature, in untethered subjects in space is a challenging task. At NASA's Ames Research Center, where a key focus is gravitational biology research, engineers have teamed with life scientists to develop wireless sensor systems for automated physiologic monitoring of animal models as small as the rat. This technology is also being adapted, in collaboration with medical professionals, to meet human clinical monitoring needs both in space and on the ground. Thus, these advanced monitoring technologies have important dual-use functions; they meet space flight data collection requirements and constraints, while concurrently addressing a number of monitoring and data acquisition challenges on the ground in areas of clinical monitoring and biomedical research. Additional applications for these and related technologies are being sought and additional partnerships established that enhance development efforts, reduce costs and facilitate technology infusion between the public and private sectors. This paper describes technology transfer and co-development projects that have evolved out of NASA's miniaturized, implantable chemical sensor development efforts.

  2. Getting a prescription filled

    MedlinePlus

    ... to get prescription filled; Pharmacy - mail order; Pharmacy - internet; Types of pharmacies ... stored at certain temperatures at a local pharmacy. INTERNET (ONLINE) PHARMACIES Internet pharmacies can be used for ...

  3. Prescriptions for ACME's Future.

    ERIC Educational Resources Information Center

    Felch, William Campbell

    1991-01-01

    Five prescriptions for the future agenda of the Alliance for Continuing Medical Education are (1) a core curriculum; (2) informatics; (3) remedial continuing medical education (CME); (4) focus on the individual learner; and (5) practice-oriented CME. (SK)

  4. 40 CFR 63.689 - Standards: Transfer systems.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ....689 Standards: Transfer systems. (a) The provisions of this section apply to the control of air... section for such air emission control. (b) For each transfer system that is subject to this section and is an individual drain system, the owner or operator shall control air emissions in accordance with...

  5. [Involvement of pharmacists in systems for supervising off-label medications: example of the CAMTEA system for the prescription of baclofen in alcohol use disorder in Northern France].

    PubMed

    Auffret, M; Rolland, B; Deheul, S; Lecomte, L; Cottencin, O; Bordet, R; Gautier, S

    2014-01-01

    Off-label prescribing matches the using of medications outside the summary of product characteristics. Adverse drug reactions are often poorly studied in off-label situations, which may expose patients to additional safety risks, and impose taking specific precautions. The current off-label prescribing practice of baclofen for alcohol-dependence in France is a typical illustration of such a situation. CAMTEA is a regional system set up in 2010 in Northern France, which gathers addiction and pharmacovigilance specialists, and aims at strengthening the prescription supervising and the monitoring of some off-label medication used for addictive disorders, especially baclofen. Until now, institution or office-based pharmacists have not been implicated, whereas they engaged their liability when delivering off-labeled treatment and they may highly contribute to the patient monitoring and the spotting of adverse events. We propose hereby possible measures for involving pharmacists into the patient supervising system developed within CAMTEA. In the current French context concerning the off-label use of baclofen, which will be the first off-label prescribing practice to be framed by a new legal disposition called "temporary use recommendation", the key role of pharmacists should be highlighted.

  6. W-314, waste transfer alternative piping system description

    SciTech Connect

    Papp, I.G.

    1998-04-30

    It is proposed that the reliability, operability, and flexibility of the Retrieval Transfer System be substantially upgraded by replacing the planned single in-farm pipeline from the AN-AY-AZ-(SY) Tank Farm Complex to the AP Farm with three parallel pipelines outside the tank farms. The proposed system provides simplified and redundant routes for the various transfer missions, and prevents the risk of transfer gridlock when the privatization effort swings into full operation.

  7. New Alert Override Codes for the Drug Utilization Review System Derived from Outpatient Prescription Data from a Tertiary Teaching Hospital in Korea

    PubMed Central

    Yoo, Ki-Bong; Kim, Woojae; Park, Man Young; Ahn, Eun Kyoung; Park, Rae Woong

    2016-01-01

    Objectives This paper proposes new alert override reason codes that are improvements on existing Drug Utilization Review (DUR) codes based on an analysis of DUR alert override cases in a tertiary medical institution. Methods Data were obtained from a tertiary teaching hospital covering the period from April 1, 2012 to January 15, 2013. We analyzed cases in which doctors had used the 11 overlapping prescription codes provided by the Health Insurance Review and Assessment Service (HIRA) or had provided free-text reasons. Results We identified 27,955 alert override cases. Among these, 7,772 (27.8%) utilized the HIRA codes, and 20,183 (72.2%) utilized free-text reasons. According to the free-text content analysis, 8,646 cases (42.8%) could be classified using the 11 HIRA codes, and 11,537 (57.2%) could not. In the unclassifiable cases, we identified the need for codes for "prescription relating to operation" and "emergency situations." Two overlapping prescription codes required removal because they were not used. Codes A, C, F, H, I, and J (for drug non-administration cases) explained surrounding situations in too much detail, making differentiation between them difficult. These 6 codes were merged into code J4: "patient was not taking/will not take the medications involved in the DDI." Of the 11 HIRA codes, 6 were merged into a single code, 2 were removed, and 2 were added, yielding 6 alert override codes. We could codify 23,550 (84.2%) alert override cases using these codes. Conclusions These new codes will facilitate the use of the drug–drug interactions alert override in the current DUR system. For further study, an appropriate evaluation should be conducted with prescribing clinicians. PMID:26893949

  8. Endogenous monitoring and enforcement of a transferable emissions permit system

    SciTech Connect

    Stranlund, J.K.; Dhanda, K.K.

    1999-11-01

    The literature on noncompliant firms in transferable emissions permit systems offers little guidance to policymakers that must determine how to commit resources to monitor firms and punish violations in such systems. The authors consider how a budget-constrained enforcement authority that seeks to minimize aggregate noncompliance in a transferable emissions permit system should allocate its monitoring and enforcement efforts among heterogeneous firms. With a conventional model of firm behavior in a transferable permit system, they find that differences in the allocation of monitoring and enforcement effort between any two types of firms should be independent of differences in their exogenous characteristics.

  9. Cooperative heat transfer and ground coupled storage system

    DOEpatents

    Metz, Philip D.

    1982-01-01

    A cooperative heat transfer and ground coupled storage system wherein collected solar heat energy is ground stored and permitted to radiate into the adjacent ground for storage therein over an extended period of time when such heat energy is seasonally maximally available. Thereafter, when said heat energy is seasonally minimally available and has propagated through the adjacent ground a substantial distance, the stored heat energy may be retrieved by a circumferentially arranged heat transfer means having a high rate of heat transfer.

  10. Cooperative heat transfer and ground coupled storage system

    DOEpatents

    Metz, P.D.

    A cooperative heat transfer and ground coupled storage system wherein collected solar heat energy is ground stored and permitted to radiate into the adjacent ground for storage therein over an extended period of time when such heat energy is seasonally maximally available. Thereafter, when said heat energy is seasonally minimally available and has propagated through the adjacent ground a substantial distance, the stored heat energy may be retrieved by a circumferentially arranged heat transfer means having a high rate of heat transfer.

  11. General Relativistic Radiative Transfer: Applications to Black-Hole Systems

    NASA Technical Reports Server (NTRS)

    Wu, Kinwah; Fuerst, Steven V.; Mizuno, Yosuke; Nishikawa, Ken-Ichi; Branduardi-Raymont, Graziella; Lee, Khee-Gan

    2007-01-01

    We present general relativistic radiation transfer formulations which include opacity effects due to absorption, emission and scattering explicitly. We consider a moment expansions for the transfer in the presence of scattering. The formulation is applied to calculation emissions from accretion and outflows in black-hole systems. Cases with thin accretion disks and accretion tori are considered. Effects, such as emission anisotropy, non-stationary flows and geometrical self-occultation are investigated. Polarisation transfer in curved space-time is discussed qualitatively.

  12. Preventing and Recognizing Prescription Drug Abuse

    MedlinePlus

    ... Abuse » Preventing and recognizing prescription drug abuse Prescription Drug Abuse Email Facebook Twitter Preventing and recognizing prescription drug abuse To ensure proper medical care, patients should discuss ...

  13. BWR Core Heat Transfer Code System.

    1999-04-27

    Version 00 MOXY is used for the thermal analysis of a planar section of a boiling water reactor (BWR) fuel element during a loss-of-coolant accident (LOCA). The code emplyoys models that describe heat transfer by conduction, convection, and thermal radiation, and heat generation by metal-water reaction and fission product decay. Models are included for considering fuel-rod swelling and rupture, energy transport across the fuel-to-cladding gap, and the thermal response of the canister. MOXY requires thatmore » time-dependent data during the blowdown process for the power normalized to the steady-state power, for the heat-transfer coefficient, and for the fluid temperature be provided as input. Internal models provide these parameters during the heatup and emergency cooling phases.« less

  14. Radiation heat transfer shapefactors for combustion systems

    NASA Technical Reports Server (NTRS)

    Emery, A. F.; Johansson, O.; Abrous, A.

    1987-01-01

    The computation of radiation heat transfer through absorbing media is commonly done through the zoning method which relies upon values of the geometric mean transmittance and absorptance. The computation of these values is difficult and expensive, particularly if many spectral bands are used. This paper describes the extension of a scan line algorithm, based upon surface-surface radiation, to the computation of surface-gas and gas-gas radiation transmittances.

  15. Convergent and Divergent Validity of the Learning Transfer System Inventory

    ERIC Educational Resources Information Center

    Holton, Elwood F., III; Bates, Reid A.; Bookter, Annette I.; Yamkovenko, V. Bogdan

    2007-01-01

    The Learning Transfer System Inventory (LTSI) was developed to identify a select set of factors with the potential to substantially enhance or inhibit transfer of learning to the work environment. It has undergone a variety of validation studies, including construct, criterion, and crosscultural studies. However, the convergent and divergent…

  16. A pneumatic transfer system for special form {sup 252}Cf

    SciTech Connect

    Gehrke, R.J.; Berry, S.M.; Grafwallner, E.G.; Hoggan, J.M.

    1996-09-01

    A pneumatic transfer system has been developed for use with series 100 Special Form {sup 252}Cf. It was developed to reduce the exposure to personnel handling sources of {sup 252}Cf with masses up to 150 {micro}g by permitting remotely activated two-way transfer between the storage container and the irradiation position. The pneumatic transfer system also permits transfers for reproducible repetitive irradiation periods. In addition to the storage container equipped with quick-release fittings, the transfer system consists of an irradiation station, a control box with momentary contact switches to activate the air-pressure control valves and indicators to identify the location of the source, and connecting air hose and electrical wire. A source of 20 psig air and 110 volt electrical power are required for operation of the transfer system which can be easily moved and set up by one individual in 5 to 10 minutes. Tests have shown that rarely does a source become lodged in the transfer tubing, but two methods have been developed to handle incomplete transfers of the {sup 252}Cf source. The first method consists of closing one air vent to allow a pressure impulse to propel the source to the opposite side. The second method applies to those {sup 252}Cf capsules with a threaded or tapped end to which a small ferromagnetic piece can be attached; an incompletely transferred source in the transfer tube can then be guided to a position of safety by surrounding the transfer tubing containing the capsule with a horseshoe magnet attached to the end of a long pole.

  17. Visual prosthesis wireless energy transfer system optimal modeling

    PubMed Central

    2014-01-01

    Background Wireless energy transfer system is an effective way to solve the visual prosthesis energy supply problems, theoretical modeling of the system is the prerequisite to do optimal energy transfer system design. Methods On the basis of the ideal model of the wireless energy transfer system, according to visual prosthesis application condition, the system modeling is optimized. During the optimal modeling, taking planar spiral coils as the coupling devices between energy transmitter and receiver, the effect of the parasitic capacitance of the transfer coil is considered, and especially the concept of biological capacitance is proposed to consider the influence of biological tissue on the energy transfer efficiency, resulting in the optimal modeling’s more accuracy for the actual application. Results The simulation data of the optimal model in this paper is compared with that of the previous ideal model, the results show that under high frequency condition, the parasitic capacitance of inductance and biological capacitance considered in the optimal model could have great impact on the wireless energy transfer system. The further comparison with the experimental data verifies the validity and accuracy of the optimal model proposed in this paper. Conclusions The optimal model proposed in this paper has a higher theoretical guiding significance for the wireless energy transfer system’s further research, and provide a more precise model reference for solving the power supply problem in visual prosthesis clinical application. PMID:24428906

  18. Exercise by prescription.

    PubMed

    Browne, D

    1997-02-01

    General Practitioners (GPs) see over 90% of their practice population in three years. Over 50% of the adult population is below the perceived level of physical activity as recognised by the Allied Dunbar Physical Activity score (Allied Dunbar, Health Education Authority and Sports Council, 1992). Physical fitness levels in adolescents and children are declining, while the incidence of obesity is increasing. GPs, with their Primary Health Care Team, are in a unique position to be able to discuss the health benefits of regular physical activity with their patients during the consultation and offer, if appropriate, a prescription for a course of physical activity to a local leisure centre or community activity centre. Many communities have facilities for physical activity. These include leisure centres, schools, village and church halls, the home and the general practice surgery. A directory of resources for physical activity for all age groups should be available in the surgery waiting room area. A community co-ordinator can network community facilities and resources to meet individual need. The co-ordinator can be funded by the general practice surgery, Health Authority, Local Authority, Parish or District Council. An agreed protocol for exercise prescription referrals to suitable community facilities can benefit patient health care for a variety of medical, surgical, social and mental conditions. Auditing exercise prescriptions shows a health benefit, with improved quality of living and reduced prescription medicines.

  19. Prescription Drug Abuse

    MedlinePlus

    ... Fitness Diseases & Conditions Infections Q&A School & Jobs Drugs & Alcohol Staying Safe Recipes En Español Making a Change – Your Personal Plan Hot Topics Meningitis Choosing Your Mood Prescription Drug Abuse Healthy School Lunch Planner How Can I ...

  20. Medicare Prescription Drug Coverage

    MedlinePlus

    ... people also have to pay an additional monthly cost. Private companies provide Medicare prescription drug coverage. You choose the drug plan you like best. Whether or not you should sign up depends on how good your current coverage is. You need to sign up as ...

  1. Prescription Opioids during Pregnancy

    MedlinePlus

    ... brand names ConZip®, Ryzolt®, Ultram®) The street drug heroin also is an opioid. What problems can opioids ... to buy them illegally. People often start using heroin after becoming addicted to prescription opioids. Sometimes opioids ...

  2. Pharmacy experience with facsimile prescriptions.

    PubMed

    Huntzinger, Paul E

    2010-11-01

    The purpose of this mixed qualitative/quantitative study was to review the impact of a policy to accept facsimile (fax) prescriptions as standard operating procedure. Between February and April 2009 the pharmacy processed 4,792 new prescriptions of which 363 (7.6%) were received through fax. Of the fax prescriptions, 19 (5.2%) concerned clarification of information, which took approximately 30 minutes to resolve. The fax prescription process allowed the pharmacy to adjust the distribution of its workload, provided quicker service for new prescriptions, and allowed more time for medication consultation that resulted in a high level of customer satisfaction. It appeared the policy allowing fax prescriptions was a "win-win" situation for both the pharmacy and its customers. Military pharmacies should consider running trials of accepting fax prescriptions to see whether it improves their prescription filling process.

  3. Pharmacy experience with facsimile prescriptions.

    PubMed

    Huntzinger, Paul E

    2010-11-01

    The purpose of this mixed qualitative/quantitative study was to review the impact of a policy to accept facsimile (fax) prescriptions as standard operating procedure. Between February and April 2009 the pharmacy processed 4,792 new prescriptions of which 363 (7.6%) were received through fax. Of the fax prescriptions, 19 (5.2%) concerned clarification of information, which took approximately 30 minutes to resolve. The fax prescription process allowed the pharmacy to adjust the distribution of its workload, provided quicker service for new prescriptions, and allowed more time for medication consultation that resulted in a high level of customer satisfaction. It appeared the policy allowing fax prescriptions was a "win-win" situation for both the pharmacy and its customers. Military pharmacies should consider running trials of accepting fax prescriptions to see whether it improves their prescription filling process. PMID:21121504

  4. Trends in Prescription Drug Abuse

    MedlinePlus

    ... Trends and Alerts Alcohol Club Drugs Cocaine Hallucinogens Heroin Inhalants Marijuana MDMA (Ecstasy/Molly) Methamphetamine Opioids Prescription ... View all ​Research Reports Opioids: The Prescription Drug & Heroin Overdose Epidemic (HHS website) NIDA Home Site Map ...

  5. Phonon-assisted excitation energy transfer in photosynthetic systems

    NASA Astrophysics Data System (ADS)

    Chen, Hao; Wang, Xin; Fang, Ai-Ping; Li, Hong-Rong

    2016-09-01

    The phonon-assisted process of energy transfer aiming at exploring the newly emerging frontier between biology and physics is an issue of central interest. This article shows the important role of the intramolecular vibrational modes for excitation energy transfer in the photosynthetic systems. Based on a dimer system consisting of a donor and an acceptor modeled by two two-level systems, in which one of them is coupled to a high-energy vibrational mode, we derive an effective Hamiltonian describing the vibration-assisted coherent energy transfer process in the polaron frame. The effective Hamiltonian reveals in the case that the vibrational mode dynamically matches the energy detuning between the donor and the acceptor, the original detuned energy transfer becomes resonant energy transfer. In addition, the population dynamics and coherence dynamics of the dimer system with and without vibration-assistance are investigated numerically. It is found that, the energy transfer efficiency and the transfer time depend heavily on the interaction strength of the donor and the high-energy vibrational mode, as well as the vibrational frequency. The numerical results also indicate that the initial state and dissipation rate of the vibrational mode have little influence on the dynamics of the dimer system. Results obtained in this article are not only helpful to understand the natural photosynthesis, but also offer an optimal design principle for artificial photosynthesis. Project supported by the National Natural Science Foundation of China (Grant No. 11174233).

  6. 46 CFR 153.430 - Heat transfer systems; general.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... this part and each cargo heating system must: (a) Meet the standards of Subchapters F (Marine... separated from all other cooling and heating systems; and (c) Allow manual regulation of the system's heat... 46 Shipping 5 2012-10-01 2012-10-01 false Heat transfer systems; general. 153.430 Section...

  7. 46 CFR 153.430 - Heat transfer systems; general.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... this part and each cargo heating system must: (a) Meet the standards of Subchapters F (Marine... separated from all other cooling and heating systems; and (c) Allow manual regulation of the system's heat... 46 Shipping 5 2011-10-01 2011-10-01 false Heat transfer systems; general. 153.430 Section...

  8. 46 CFR 153.430 - Heat transfer systems; general.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... this part and each cargo heating system must: (a) Meet the standards of Subchapters F (Marine... separated from all other cooling and heating systems; and (c) Allow manual regulation of the system's heat... 46 Shipping 5 2013-10-01 2013-10-01 false Heat transfer systems; general. 153.430 Section...

  9. 46 CFR 153.430 - Heat transfer systems; general.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... this part and each cargo heating system must: (a) Meet the standards of Subchapters F (Marine... separated from all other cooling and heating systems; and (c) Allow manual regulation of the system's heat... 46 Shipping 5 2014-10-01 2014-10-01 false Heat transfer systems; general. 153.430 Section...

  10. 46 CFR 153.430 - Heat transfer systems; general.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... this part and each cargo heating system must: (a) Meet the standards of Subchapters F (Marine... separated from all other cooling and heating systems; and (c) Allow manual regulation of the system's heat... 46 Shipping 5 2010-10-01 2010-10-01 false Heat transfer systems; general. 153.430 Section...

  11. High Quality Factor Resonators for Inductive Power Transfer Systems

    NASA Astrophysics Data System (ADS)

    Etemadrezaei, Mohammad

    In this dissertation, the Inductive Power Transfer (IPT) systems for multi-MHz frequency of operation are investigated, and new ideas for magnetic link inductive coils are presented. (Abstract shortened by ProQuest.).

  12. Jet-impingement heat transfer in gas turbine systems.

    PubMed

    Han, B; Goldstein, R J

    2001-05-01

    A review of jet-impingement heat transfer in gas turbine systems is presented. Characteristics of the different flow regions for submerged jets--free jet, stagnation flow, and wall jet--are reviewed. Heat transfer characteristics of both single and multiple jets are discussed with consideration of the effects of important parameters relevant to gas turbine systems including curvature of surfaces, crossflow, angle of impact, and rotation.

  13. Modified transfer matrix method for asymmetric rotor-bearing systems

    NASA Astrophysics Data System (ADS)

    Kang, Yuan; Lee, An-Chen; Shih, Yuan-Pin

    1994-07-01

    A modified transfer matrix method (MTMM) is developed to analyze rotor-bearing systems with an asymmetric shaft and asymmetric disks. The rotating shaft is modeled by a Rayleigh-Euler beam considering the effects of the rotary inertia and gyroscopic moments. Specifically, a transfer matrix of the asymmetric shaft segments is derived in a continuous-system sense to give accurate solutions. The harmonic balance method is incorporated in the transfer matrix equations, so that steady-state responses of synchronous and superharmonic whirls can be determined. A numerical example is presented to demonstrate the effectiveness of this approach.

  14. Volcanic hazard warning system: Persistence and transferability

    NASA Astrophysics Data System (ADS)

    Sorensen, John H.; Gersmehl, Philip J.

    1980-03-01

    This study examines the normative functioning of the volcano warning system on the Island of Hawaii. The research seeks to identify the combination of factors, both environmental and social, which allows the system to operate with success. On the basis of the findings, several recommendations are offered for improving environmental hazard warning systems.

  15. Design of auto-tuning capacitive power transfer system for wireless power transfer

    NASA Astrophysics Data System (ADS)

    Lu, Kai; Kiong Nguang, Sing

    2016-09-01

    This paper presents the design of capacitive wireless power transfer systems based on a Class-E inverter approach. The main reason for adopting the Class-E inverter approach is because of its high efficiency, theoretically 100%. However, the operation of a Class-E inverter is highly sensitive to its circuit's parameters. In a typical capacitive wireless power transfer application, the capacitive coupling distance between plates is subject to changes, and hence its power transfer efficiency is greatly affected if the Class-E inverter is properly tuned. This drawback motivates us to develop an auto frequency tuning algorithm for a Class-E inverter which maintains its power transfer efficiency in spite of the variations of capacitive coupling distances between plates and circuit's parameters. Finally, simulation and experiment are carried out to verify the effectiveness of the auto frequency tuning algorithm.

  16. How Can Geographical Information Systems and Spatial Analysis Inform a Response to Prescription Opioid Misuse? A Discussion in the Context of Existing Literature.

    PubMed

    Mazumdar, Soumya; Mcrae, Ian S; Islam, M Mofizul

    2015-01-01

    The misuse of prescription opioids is a major public health problem in the United States, Canada, Australia and other parts of the developed world. Methods to quantify dimensions of the risk environment in relation to drug usage and law enforcement that are both structural and spatial, draw geography into traditional public health research even though there has been limited attempt to address the prescription opioid misuse problem from a geographic perspective. We discuss how geographic technologies can be utilized to study the landscape of prescription opioids and similar drugs, and target appropriate health services interventions. We use examples drawn from various jurisdictions to present our case and highlight through these examples how a geospatial perspective can help support research on prescription opioid misuse. The prescription drug misuse landscape can be studied through examination of the domains of demand, supply, harms and harm reduction. We discuss how each of these domains can benefit from a local geographic perspective, and subsequent geographic exploration and analyses.

  17. Topological energy transfer in an optomechanical system with exceptional points

    NASA Astrophysics Data System (ADS)

    Xu, H.; Mason, D.; Jiang, Luyao; Harris, J. G. E.

    2016-09-01

    Topological operations can achieve certain goals without requiring accurate control over local operational details; for example, they have been used to control geometric phases and have been proposed as a way of controlling the state of certain systems within their degenerate subspaces. More recently, it was predicted that topological operations can be used to transfer energy between normal modes, provided that the system possesses a specific type of degeneracy known as an exceptional point. Here we demonstrate the transfer of energy between two vibrational modes of a cryogenic optomechanical device using topological operations. We show that this transfer arises from the presence of an exceptional point in the spectrum of the device. We also show that this transfer is non-reciprocal. These results open up new directions in system control; they also open up the possibility of exploring other dynamical effects related to exceptional points, including the behaviour of thermal and quantum fluctuations in their vicinity.

  18. Rapid Resolution Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics Approach to Study the Effects of Jieduquyuziyin Prescription on Systemic Lupus Erythematosus

    PubMed Central

    Wen, Chengping; Ding, Zhishan; Yao, Li; Fan, Yongsheng

    2014-01-01

    Jieduquyuziyin prescription (JP), a traditional Chinese medicine (TCM) prescription, has been widely used for the clinical treatment of systemic lupus erythematosus (SLE). However, the complex chemical constituents of JP and the multifactorial pathogenesis of SLE make research on the therapeutic mechanism of JP in SLE challenging. In this paper, a serum metabolomics approach based on rapid resolution liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (RRLC-Q-TOF/MS) was employed to acquire the metabolic characteristics of serum samples obtained from mice in the SLE model group, JP-treated group, prednisone acetate (PA)-treated group and control group. The orthogonal partial least squares (OPLS) was applied to recognize metabolic patterns, and an obvious separation of groups was obtained. Thirteen metabolites, namely, phosphatidylethanolamine (PE 20:3), hepoxilin B3, lyso- phosphatidylethanolamine (lyso-PE 22:6), 12S-hydroxypentaenoic acid (12S-HEPE), traumatic acid, serotonin, platelet-activating factor (PAF), phosphatidylcholine (PC 20:5),eicosapentaenoic acid (EPA), 12(S)-hydroxyei- cosatetraenoic acid (12S-HETE), 14-hydroxy docosahexaenoic acid (14-HDOHE), lyso-phosphatidylcholine (lyso-PC 20:4), and indole acetaldehyde, were identified and characterized as differential metabolites involved in the pathogenesis of SLE. After treatment with JP, the relative content of 12(S)-HETE, PAF, 12(S)-HEPE, EPA, PE (20:3), Lyso-PE(22:6), and 14-HDOHE were effectively regulated, which suggested that the therapeutic effects of JP on SLE may involve regulating disturbances to the metabolism of unsaturated fatty acid, tryptophan and phospholipid. This research also demonstrated that metabolomics is a powerful tool for researching complex disease mechanisms and evaluating the mechanism of action of TCM. PMID:24505438

  19. Solids modeller to drafting system transfer program

    SciTech Connect

    Robbins, D.

    1983-03-01

    A Solids Modeller in use at Sandia National Laboratories (Albuquerque), PADL2 has been interfaced to a Turnkey Drafting System, Applicon. This interface permits design at the high level of the Solids Modeller with dimensioning and drawing production at the turnkey drafting system.

  20. Thermal energy transfer system and method

    SciTech Connect

    Knoos, S.

    1985-02-12

    A thermodynamic system for interchanging thermal energy with external sources or sinks while minimizing the dead volume presented to the pressure cycle is based upon a thermodynamic machine which cycles a working fluid bidirectionally through a regenerator means and at least one external heat exchanger for interchanging thermal energy with a heat source or sink. Between the thermodynamic machine and the heat exchanger is a switchable thermal energy storage system using at least one heat load capacitor and two different circulation loops through the storage system. By switching the working fluid paths through the thermal energy storage system, Thermal energy is exchanged but the thermodynamic machine is isolated from the heat exchanger at least predetermined intervals during operation, and the dead space in the external device does not affect the pressure cycle of the machine.

  1. Radiative heat transfer in low-dimensional systems -- microscopic mode

    NASA Astrophysics Data System (ADS)

    Woods, Lilia; Phan, Anh; Drosdoff, David

    2013-03-01

    Radiative heat transfer between objects can increase dramatically at sub-wavelength scales. Exploring ways to modulate such transport between nano-systems is a key issue from fundamental and applied points of view. We advance the theoretical understanding of radiative heat transfer between nano-objects by introducing a microscopic model, which takes into account the individual atoms and their atomic polarizabilities. This approach is especially useful to investigate nano-objects with various geometries and give a detailed description of the heat transfer distribution. We employ this model to study the heat exchange in graphene nanoribbon/substrate systems. Our results for the distance separations, substrates, and presence of extended or localized defects enable making predictions for tailoring the radiative heat transfer at the nanoscale. Financial support from the Department of Energy under Contract No. DE-FG02-06ER46297 is acknowledged.

  2. Enhanced heat transfer in partially-saturated hydrothermal systems

    SciTech Connect

    Bixler, N.E.; Carrigan, C.R.

    1986-01-01

    The role of capillarity is potentially important for determining heat transfer in hydrothermal regions. Capillarity allows mixing of phases in liquid/vapor systems and results in enhanced two-phase convection. Comparisons involving a numerical model with capillarity and analytical models without indicate that heat transfer can be enhanced by about an order of magnitude. Whether capillarity can be important for a particular hydrothermal region will depend on the nature of mineral precipitation as well as pore and fracture size distributions.

  3. Learning Transfer--Validation of the Learning Transfer System Inventory in Portugal

    ERIC Educational Resources Information Center

    Velada, Raquel; Caetano, Antonio; Bates, Reid; Holton, Ed

    2009-01-01

    Purpose: The purpose of this paper is to analyze the construct validity of learning transfer system inventory (LTSI) for use in Portugal. Furthermore, it also aims to analyze whether LTSI dimensions differ across individual variables such as gender, age, educational level and job tenure. Design/methodology/approach: After a rigorous translation…

  4. Material transfer system in support of the plutonium immobilization program

    SciTech Connect

    Pak, D

    2000-12-20

    The Plutonium Immobilization Program requires development of the process and plant prototypic equipment to immobilize surplus plutonium in ceramic for long-term storage. Because of the hazardous nature of plutonium, it was necessary to develop a remotely operable materials transfer system which can function within the confines of a glovebox. In support of this work at LLNL, such a material transfer system (MTS) was developed. This paper presents both the mechanical and controls parts making up this system, and includes photographs of the key components and diagrams of their assemblies, as well as a description of the control sequence used to validate the MTS capabilities.

  5. Polarized radiative transfer equation in several astrophysically interesting coordinate systems

    NASA Astrophysics Data System (ADS)

    Freimanis, J.

    2012-04-01

    While modeling multiple light scattering in astrophysical objects generally it is necessary to make numerical 3D radiative transfer calculations in objects of irregular morphology. But often their shape can be approximated by some regular geometry, e.g. plane-parallel, spherical, cylindrical, conical, spheroidal or toroidal. There are few theoretical results concerning radiative transfer in nonplanar geometries, namely, only for spherical and cylindrical coordinate systems. But the numerical solution of any equation generally performs best if the numerical method accounts for the analytical properties of the solution, first of all - its singularities and asymptotics. This justifies further theoretical research of radiative transfer in different coordinate systems, and first of all, the transfer equation itself in different coordinate systems must be written down. General method allowing to obtain clear expression for the differential operator of polarized radiative transfer equation (PRTE) in arbitrary curvilinear spatial coordinate system was recently described [1]. Here it is applied to several orthogonal coordinate systems essential for astrophysical applications. PRTE in circular conical coordinate system is treated as a particular look upon PRTE in spherical coordinate system. Previously obtained expressions for PRTE in elliptic conical coordinate system [2] are simplified using Lukáčs [3] trigonometric parameterization of the coordinates. PRTE in triaxial ellipsoidal system is obtained by merger of parameterization of angular coordinates described in [3] with my own ideas; PRTE in oblate spheroidal and prolate spheroidal system appear as particular cases of it in two types of the ellipsoidal system. PRTE in two different kinds of toroidal coordinate system (classical and simple) is derived as well.

  6. Control System and Flexible Satellite Interaction During Orbit Transfer Maneuver

    NASA Technical Reports Server (NTRS)

    daSilva, Adenilson Roberto; GadelhadeSouza, Luiz Carlos

    1998-01-01

    In this paper the interaction between the attitude control system and the flexible structure of an artificial satellite during orbit transfer maneuver has been investigated. The satellite was modeled by a rigid central body with one or more flexible appendages. The dynamics equations were obtained by Lagrangean approach. The flexible appendages were treated as clamped-free beam and its displacement was discretized by assumed- mode method. In order to transfer the satellite, a typical Hohmann transfer and a burn-coast-burn strategy were used and the attitude was controlled by an on-off controller. During transfer procedure a global analysis of satellite has been done, such as: performance of control system, influence of elastic response in control system, thruster firing frequency, fuel consumption and variation of orbital elements. In order to avoid the interaction with structure motion, a control system with bandwidth of one decade bellow the fundamental frequency was used. In the simulations the firing frequency was evaluated in an approximately way but kept below the fundamental frequency of the structure. The control system has kept the attitude below the specifications. As a result, the orbit transfer maneuvering has been done correctly without excessive excitation of flexible appendage.

  7. Prescription Drug Abuse Information in D.A.R.E.

    ERIC Educational Resources Information Center

    Morris, Melissa C.; Cline, Rebecca J. Welch; Weiler, Robert M.; Broadway, S. Camille

    2006-01-01

    This investigation was designed to examine prescription drug-related content and learning objectives in Drug Abuse Resistance Education (D.A.R.E.) for upper elementary and middle schools. Specific prescription-drug topics and context associated with content and objectives were coded. The coding system for topics included 126 topics organized…

  8. 40 CFR 63.689 - Standards: Transfer systems.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... standards specified in 40 CFR part 63, subpart RR—National Emission Standards for Individual Drain Systems... transfer system is designed and operated such that an internal pressure in the vapor headspace in the enclosure is maintained at a level less than atmospheric pressure when the control device is operating,...

  9. A Comprehensive and Integrated Automated Transfer Evaluation System.

    ERIC Educational Resources Information Center

    Kramer, Gary L.; And Others

    1992-01-01

    Brigham Young University (Utah) has an automated system for evaluating student transfer information, using an established database containing a historical record of courses taken at other schools. A unique feature of the system is that course evaluation and degree audit are completed the day the student is admitted. (Author/MSE)

  10. Transfer Effects in Learning a Second Language Grammatical Gender System

    ERIC Educational Resources Information Center

    Sabourin, Laura; Stowe, Laurie A.; de Haan, Ger J.

    2006-01-01

    In this article second language (L2) knowledge of Dutch grammatical gender is investigated. Adult speakers of German, English and a Romance language (French, Italian or Spanish) were investigated to explore the role of transfer in learning the Dutch grammatical gender system. In the first language (L1) systems, German is the most similar to Dutch…

  11. 5 CFR 843.210 - Transfers between retirement systems.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false Transfers between retirement systems. 843.210 Section 843.210 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES RETIREMENT SYSTEM-DEATH BENEFITS AND EMPLOYEE REFUNDS...

  12. 5 CFR 843.210 - Transfers between retirement systems.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Transfers between retirement systems. 843.210 Section 843.210 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES RETIREMENT SYSTEM-DEATH BENEFITS AND EMPLOYEE REFUNDS...

  13. 5 CFR 843.210 - Transfers between retirement systems.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Transfers between retirement systems. 843.210 Section 843.210 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES RETIREMENT SYSTEM-DEATH BENEFITS AND EMPLOYEE REFUNDS...

  14. 5 CFR 843.210 - Transfers between retirement systems.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false Transfers between retirement systems. 843.210 Section 843.210 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES RETIREMENT SYSTEM-DEATH BENEFITS AND EMPLOYEE REFUNDS...

  15. 5 CFR 843.210 - Transfers between retirement systems.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Transfers between retirement systems. 843.210 Section 843.210 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED) FEDERAL EMPLOYEES RETIREMENT SYSTEM-DEATH BENEFITS AND EMPLOYEE REFUNDS...

  16. Operational test report for 2706-T complex liquid transfer system

    SciTech Connect

    BENZEL, H.R.

    1999-09-01

    This document is the Operational Test Report (OTR). It enters the Record Copy of the W-259 Operational Test Procedure (HNF-3610) into the document retrieval system. Additionally, the OTR summarizes significant issues associated with testing the 2706-T waste liquid transfer and storage system.

  17. [Analysis on composition principles of prescriptions for stranguria in dictionary of traditional Chinese medicine prescription].

    PubMed

    Sun, Jing-Chang; Wang, Miao-Miao

    2014-03-01

    By using traditional Chinese medicine inheritance support system to analyze the dominant experience and recessive principles of the prescriptions for stranguria in the dictionary of traditional Chinese medicine prescription (DCMP), we aim to define the medication pattern and rule and to acquire new prescriptions. In dominant experience analysis, we were able to find 22 drugs used over 50 times, including drugs of clearing heat, diuresis and relieving stranguria which are the most used and drugs of clearing heat, cooling blood, benefiting Qi and nourishing Yin. In addition, drugs of activating Qi and Xue, eliminating phlegm and removing toxic are often used, including 34 herb pairs and 5 combinations of three-taste drugs are used more than 35 times. These results fully reflect the composition principles and compatibility characteristic of prescriptions for treating stranguria in DCMP. Thirteen new prescriptions by way of recessive principle excavating were acquired. These new prescriptions might be suitable to clinical treatments of variable syndromes. This article provides an useful clue to research and produce new drugs. PMID:24956864

  18. Radiative transfer in atmosphere-sea ice-ocean system

    SciTech Connect

    Jin, Z.; Stamnes, K.; Weeks, W.F.; Tsay, S.C.

    1996-04-01

    Radiative energy is critical in controlling the heat and mass balance of sea ice, which significantly affects the polar climate. In the polar oceans, light transmission through the atmosphere and sea ice is essential to the growth of plankton and algae and, consequently, to the microbial community both in the ice and in the ocean. Therefore, the study of radiative transfer in the polar atmosphere, sea ice, and ocean system is of particular importance. Lacking a properly coupled radiative transfer model for the atmosphere-sea ice-ocean system, a consistent study of the radiative transfer in the polar atmosphere, snow, sea ice, and ocean system has not been undertaken before. The radiative transfer processes in the atmosphere and in the ice and ocean have been treated separately. Because the radiation processes in the atmosphere, sea ice, and ocean depend on each other, this separate treatment is inconsistent. To study the radiative interaction between the atmosphere, clouds, snow, sea ice, and ocean, a radiative transfer model with consistent treatment of radiation in the coupled system is needed and is under development.

  19. Advanced two-phase heat transfer systems

    NASA Technical Reports Server (NTRS)

    Swanson, Theodore D.

    1992-01-01

    Future large spacecraft, such as the Earth Observing System (EOS) platforms, will require a significantly more capable thermal control system than is possible with current 'passive' technology. Temperatures must be controlled much more tightly over a larger surface area. Numerous heat load sources will often be located inside the body of the spacecraft without a good view to space. Power levels and flux densities may be higher than can be accommodated with traditional technology. Integration and ground testing will almost certainly be much more difficult with such larger, more complex spacecraft. For these and similar reasons, the Goddard Space Flight Center (GSFC) has been developing a new, more capable thermal control technology called capillary pumped loops (CPL's). CPL's represent an evolutionary improvement over heat pipes; they can transport much greater quantities of heat over much longer distances and can serve numerous heat load sources. In addition, CPL's can be fabricated into large cold plates that can be held to tight thermal gradients. Development of this technology began in the early 1980's and is now reaching maturity. CPL's have recently been baselined for the EOS-AM platform (1997 launch) and the COMET spacecraft (1992 launch). This presentation describes this new technology and its applications. Most of the viewgraphs are self descriptive. For those that are less clear additional comments are provided.

  20. Advanced two-phase heat transfer systems

    NASA Astrophysics Data System (ADS)

    Swanson, Theodore D.

    1992-10-01

    Future large spacecraft, such as the Earth Observing System (EOS) platforms, will require a significantly more capable thermal control system than is possible with current 'passive' technology. Temperatures must be controlled much more tightly over a larger surface area. Numerous heat load sources will often be located inside the body of the spacecraft without a good view to space. Power levels and flux densities may be higher than can be accommodated with traditional technology. Integration and ground testing will almost certainly be much more difficult with such larger, more complex spacecraft. For these and similar reasons, the Goddard Space Flight Center (GSFC) has been developing a new, more capable thermal control technology called capillary pumped loops (CPL's). CPL's represent an evolutionary improvement over heat pipes; they can transport much greater quantities of heat over much longer distances and can serve numerous heat load sources. In addition, CPL's can be fabricated into large cold plates that can be held to tight thermal gradients. Development of this technology began in the early 1980's and is now reaching maturity. CPL's have recently been baselined for the EOS-AM platform (1997 launch) and the COMET spacecraft (1992 launch). This presentation describes this new technology and its applications. Most of the viewgraphs are self descriptive. For those that are less clear additional comments are provided.

  1. Methods for Gene Transfer to the Central Nervous System

    PubMed Central

    Kantor, Boris; Bailey, Rachel M.; Wimberly, Keon; Kalburgi, Sahana N.; Gray, Steven J.

    2015-01-01

    Gene transfer is an increasingly utilized approach for research and clinical applications involving the central nervous system (CNS). Vectors for gene transfer can be as simple as an unmodified plasmid, but more commonly involve complex modifications to viruses to make them suitable gene delivery vehicles. This chapter will explain how tools for CNS gene transfer have been derived from naturally occurring viruses. The current capabilities of plasmid, retroviral, adeno-associated virus, adenovirus, and herpes simplex virus vectors for CNS gene delivery will be described. These include both focal and global CNS gene transfer strategies, with short- or long-term gene expression. As is described in this chapter, an important aspect of any vector is the cis-acting regulatory elements incorporated into the vector genome that control when, where, and how the transgene is expressed. PMID:25311922

  2. Development of a multitask and multiinstrument sample transfer system

    SciTech Connect

    Thevuthasan, S.; Baer, D.R.; Englehard, M.H.; Liang, Y.; Worthington, J.N.; Howard, T.R.; Munn, J.R.; Rounds, K.S.

    1995-07-01

    A multiinstrument, multitask UHV sample transfer system being developed for integration with a wide range of synthesis and analysis instruments is described. The specimen transfer capability allows a sample to be synthesized, processed, and characterized by several surface science techniques without exposing the sample to air. Although several types of transfer systems now exist, no existing system has the range of operation desired for a user facility which will be equipped with a wide range of vacuum and controlled atmosphere-based techniques. Three different kinds of sample platens, which can be used in ambient, high-temperature, and surface chemistry experiments, have been designed and tested. The temperature range of the specimen can be as high as 2000 K during heating and as low as 150 K during cooling. {copyright} {ital 1995} {ital American} {ital Vacuum} {ital Society}

  3. Method of measuring heat influx of a cryogenic transfer system

    DOEpatents

    Niemann, Ralph C.; Zelipsky, Steven A.; Rezmer, Ronald R.; Smelser, Peter

    1981-01-01

    A method is provided for measuring the heat influx of a cryogenic transfer system. A gaseous phase of the cryogen used during normal operation of the system is passed through the system. The gaseous cryogen at the inlet to the system is tempered to duplicate the normal operating temperature of the system inlet. The temperature and mass flow rate of the gaseous cryogen is measured at the outlet of the system, and the heat capacity of the cryogen is determined. The heat influx of the system is then determined from known thermodynamic relationships.

  4. Heat and mass transfer considerations in advanced heat pump systems

    SciTech Connect

    Panchal, C.B.; Bell, K.J.

    1992-01-01

    Advanced heat-pump cycles are being investigated for various applications. However, the working media and associated thermal design aspects require new concepts for maintaining high thermal effectiveness and phase equilibrium for achieving maximum possible thermodynamic advantages. In the present study, the heat- and mass-transfer processes in two heat-pump systems -- those based on absorption processes, and those using refrigerant mixtures -- are analyzed. The major technical barriers for achieving the ideal performance predicted by thermodynamic analysis are identified. The analysis provides general guidelines for the development of heat- and mass-transfer equipment for advanced heat-pump systems.

  5. Heat and mass transfer considerations in advanced heat pump systems

    SciTech Connect

    Panchal, C.B.; Bell, K.J.

    1992-08-01

    Advanced heat-pump cycles are being investigated for various applications. However, the working media and associated thermal design aspects require new concepts for maintaining high thermal effectiveness and phase equilibrium for achieving maximum possible thermodynamic advantages. In the present study, the heat- and mass-transfer processes in two heat-pump systems -- those based on absorption processes, and those using refrigerant mixtures -- are analyzed. The major technical barriers for achieving the ideal performance predicted by thermodynamic analysis are identified. The analysis provides general guidelines for the development of heat- and mass-transfer equipment for advanced heat-pump systems.

  6. Deprescription: The prescription metabolism

    PubMed Central

    Sivagnanam, Gurusamy

    2016-01-01

    Deprescribing is a structured approach to drug discontinuation. An alternative suggested term is “prescription metabolism.” The major aim of deprescription is to purge the drug(s) considered unwanted in a given patient, especially in the elderly patients with multiple comorbidities or in those suffering from chronic disease. Like drug metabolism, prescription metabolism is a way of eliminating unwanted, troublesome, or cost-ineffective medications. The removal of such drugs has been found to decrease the incidence of adverse drug reactions and improves the rate of medication adherence, thereby reducing the economic burden on the patient as well as on the health care providers. Certain categories of drugs are to be tapered rather than abruptly stopped. Despite the availability of many tools to minimize drug therapy-related problems, there is little guidance for the process of deprescribing in general clinical practice. Various methods to reduce the risks of polypharmacy include patient education, physician education, and regulatory intervention. The suggested S and S approach (seek and screen, save and severe, sensitize and supervise) may be tried for deprescribing in general practice. More research on deprescribing is the need of the hour in almost all branches of clinical medicine which may pave the way for the betterment of health care. PMID:27651709

  7. Deprescription: The prescription metabolism.

    PubMed

    Sivagnanam, Gurusamy

    2016-01-01

    Deprescribing is a structured approach to drug discontinuation. An alternative suggested term is "prescription metabolism." The major aim of deprescription is to purge the drug(s) considered unwanted in a given patient, especially in the elderly patients with multiple comorbidities or in those suffering from chronic disease. Like drug metabolism, prescription metabolism is a way of eliminating unwanted, troublesome, or cost-ineffective medications. The removal of such drugs has been found to decrease the incidence of adverse drug reactions and improves the rate of medication adherence, thereby reducing the economic burden on the patient as well as on the health care providers. Certain categories of drugs are to be tapered rather than abruptly stopped. Despite the availability of many tools to minimize drug therapy-related problems, there is little guidance for the process of deprescribing in general clinical practice. Various methods to reduce the risks of polypharmacy include patient education, physician education, and regulatory intervention. The suggested S and S approach (seek and screen, save and severe, sensitize and supervise) may be tried for deprescribing in general practice. More research on deprescribing is the need of the hour in almost all branches of clinical medicine which may pave the way for the betterment of health care. PMID:27651709

  8. Prescription drug abuse information in D.A.R.E.

    PubMed

    Morris, Melissa C; Cline, Rebecca J Welch; Weiler, Robert M; Broadway, S Camille

    2006-01-01

    This investigation was designed to examine prescription drug-related content and learning objectives in Drug Abuse Resistance Education (D.A.R.E.) for upper elementary and middle schools. Specific prescription-drug topics and context associated with content and objectives were coded. The coding system for topics included 126 topics organized within 14 categories. A two-dimensional coding system for context identified Use versus Abuse and Explicit versus Implicit references to prescription drugs. Results indicated that content and objectives found in D.A.R.E. represent a very narrow breadth of prescription drug topics. Moreover, all prescription-drug related content and objectives were presented in an Abuse-Implicit context. Although some educational material in D.A.R.E. modules potentially is related to prescription drugs, none of the content or objectives explicitly identify drugs discussed as prescription drugs. If elementary and middle schools rely on D.A.R.E. modules to teach students about drug abuse, students are likely to be underinformed about prescription drug risks. PMID:16981638

  9. Optimal Energy Transfer in Light-Harvesting Systems.

    PubMed

    Chen, Lipeng; Shenai, Prathamesh; Zheng, Fulu; Somoza, Alejandro; Zhao, Yang

    2015-08-20

    Photosynthesis is one of the most essential biological processes in which specialized pigment-protein complexes absorb solar photons, and with a remarkably high efficiency, guide the photo-induced excitation energy toward the reaction center to subsequently trigger its conversion to chemical energy. In this work, we review the principles of optimal energy transfer in various natural and artificial light harvesting systems. We begin by presenting the guiding principles for optimizing the energy transfer efficiency in systems connected to dissipative environments, with particular attention paid to the potential role of quantum coherence in light harvesting systems. We will comment briefly on photo-protective mechanisms in natural systems that ensure optimal functionality under varying ambient conditions. For completeness, we will also present an overview of the charge separation and electron transfer pathways in reaction centers. Finally, recent theoretical and experimental progress on excitation energy transfer, charge separation, and charge transport in artificial light harvesting systems is delineated, with organic solar cells taken as prime examples.

  10. Optimal Energy Transfer in Light-Harvesting Systems.

    PubMed

    Chen, Lipeng; Shenai, Prathamesh; Zheng, Fulu; Somoza, Alejandro; Zhao, Yang

    2015-01-01

    Photosynthesis is one of the most essential biological processes in which specialized pigment-protein complexes absorb solar photons, and with a remarkably high efficiency, guide the photo-induced excitation energy toward the reaction center to subsequently trigger its conversion to chemical energy. In this work, we review the principles of optimal energy transfer in various natural and artificial light harvesting systems. We begin by presenting the guiding principles for optimizing the energy transfer efficiency in systems connected to dissipative environments, with particular attention paid to the potential role of quantum coherence in light harvesting systems. We will comment briefly on photo-protective mechanisms in natural systems that ensure optimal functionality under varying ambient conditions. For completeness, we will also present an overview of the charge separation and electron transfer pathways in reaction centers. Finally, recent theoretical and experimental progress on excitation energy transfer, charge separation, and charge transport in artificial light harvesting systems is delineated, with organic solar cells taken as prime examples. PMID:26307957

  11. Dynamics of entanglement transfer through multipartite dissipative systems

    SciTech Connect

    Lopez, C. E.; Retamal, J. C.; Romero, G.

    2010-06-15

    We study the dynamics of entanglement transfer in a system composed of two initially correlated three-level atoms, each located in a cavity interacting with its own reservoir. Instead of tracing out reservoir modes to describe the dynamics using the master equation approach, we consider explicitly the dynamics of the reservoirs. In this situation, we show that the entanglement is completely transferred from atoms to reservoirs. Although the cavities mediate this entanglement transfer, we show that under certain conditions, no entanglement is found in cavities throughout the dynamics. Considering the entanglement dynamics of interacting and noninteracting bipartite subsystems, we found time windows where the entanglement can only flow through interacting subsystems, depending on the system parameters.

  12. Anti-malarial prescription practices among outpatients with laboratory-confirmed malaria in the setting of a health facility-based sentinel site surveillance system in Uganda

    PubMed Central

    2013-01-01

    Background Most African countries have adopted artemisinin-based combination therapy (ACT) as the first-line treatment for uncomplicated malaria. The World Health Organization now recommends limiting anti-malarial treatment to those with a positive malaria test result. Limited data exist on how these policies have affected ACT prescription practices. Methods Data were collected from all outpatients presenting to six public health facilities in Uganda as part of a sentinel site malaria surveillance programme. Training in case management, encouragement of laboratory-based diagnosis of malaria, and regular feedback were provided. Data for this report include patients with laboratory confirmed malaria who were prescribed anti-malarial therapy over a two-year period. Patient visits were analysed in two groups: those considered ACT candidates (defined as uncomplicated malaria with no referral for admission in patients ≥ 4 months of age and ≥ 5 kg in weight) and those who may not have been ACT candidates. Associations between variables of interest and failure to prescribe ACT to patients who were ACT candidates were estimated using multivariable logistic regression. Results A total of 51,355 patient visits were included in the analysis and 46,265 (90.1%) were classified as ACT candidates. In the ACT candidate group, 94.5% were correctly prescribed ACT. Artemether-lumefantrine made up 97.3% of ACT prescribed. There were significant differences across the sites in the proportion of patients for whom there was a failure to prescribe ACT, ranging from 3.0-9.3%. Young children and woman of childbearing age had higher odds of failure to receive an ACT prescription. Among patients who may not have been ACT candidates, the proportion prescribed quinine versus ACT differed based on if the patient had severe malaria or was referred for admission (93.4% vs 6.5%) or was below age or weight cutoffs for ACT (41.4% vs 57.2%). Conclusions High rates of compliance with

  13. Considerations for an exercise prescription

    NASA Technical Reports Server (NTRS)

    Convertino, Victor A.

    1989-01-01

    A number of past and most recent research findings that describe some of the physiological responses to exercise in man and their relationship with exposure to various gravitational environments are discussed. Most of the data pertain to adaptations of the cardiovascular and body fluid systems. It should be kept in mind that the data from studies on microgravity simulation in man include exposures of relatively short duration (5 hours to 14 days). However, it is argued that the results may provide important guidelines for the consideration of many variables which are pertinent to the development of exercise prescription for long-duration space flight. The following considerations for exercise prescriptions during long-duration space flight are noted: (1) Relatively high aerobic fitness and strength, especially of the upper body musculature, should be a criterion for selection of astronauts who will be involved in EVA, since endurance and strength appear to be predominant characteristics for work performance. (2) Some degree of upper body strength will probably be required for effective performance of EVA. However, the endurance and strength required by the upper body for EVA can probably be obtained through preflight exercise prescription which involves swimming. (3) Although some degree of arm exercise may be required to maintain preflight endurance and strength, researchers propose that regular EVA will probably be sufficient to maintain the endurance and strength required to effectively perform work tasks during space flight. (4) A minimum of one maximal aerobic exercise every 7 to 10 days during space flight may be all that is necessary for maintenance of normal cardiovascular responsiveness and replacement of body fluids for reentry following prolonged space flight. (5) The possible reduction in the amount of exercise required for maintenance of cardiovascular system and body fluids in combination with the use of electromyostimulation (EMS) or methods other

  14. Automatic graphene transfer system for improved material quality and efficiency.

    PubMed

    Boscá, Alberto; Pedrós, Jorge; Martínez, Javier; Palacios, Tomás; Calle, Fernando

    2016-02-10

    In most applications based on chemical vapor deposition (CVD) graphene, the transfer from the growth to the target substrate is a critical step for the final device performance. Manual procedures are time consuming and depend on handling skills, whereas existing automatic roll-to-roll methods work well for flexible substrates but tend to induce mechanical damage in rigid ones. A new system that automatically transfers CVD graphene to an arbitrary target substrate has been developed. The process is based on the all-fluidic manipulation of the graphene to avoid mechanical damage, strain and contamination, and on the combination of capillary action and electrostatic repulsion between the graphene and its container to ensure a centered sample on top of the target substrate. The improved carrier mobility and yield of the automatically transferred graphene, as compared to that manually transferred, is demonstrated by the optical and electrical characterization of field-effect transistors fabricated on both materials. In particular, 70% higher mobility values, with a 30% decrease in the unintentional doping and a 10% strain reduction are achieved. The system has been developed for lab-scale transfer and proved to be scalable for industrial applications.

  15. Production and Transfer of Energy and Information in Hamiltonian Systems

    PubMed Central

    Antonopoulos, Chris G.; Bianco-Martinez, Ezequiel; Baptista, Murilo S.

    2014-01-01

    We present novel results that relate energy and information transfer with sensitivity to initial conditions in chaotic multi-dimensional Hamiltonian systems. We show the relation among Kolmogorov-Sinai entropy, Lyapunov exponents, and upper bounds for the Mutual Information Rate calculated in the Hamiltonian phase space and on bi-dimensional subspaces. Our main result is that the net amount of transfer from kinetic to potential energy per unit of time is a power-law of the upper bound for the Mutual Information Rate between kinetic and potential energies, and also a power-law of the Kolmogorov-Sinai entropy. Therefore, transfer of energy is related with both transfer and production of information. However, the power-law nature of this relation means that a small increment of energy transferred leads to a relatively much larger increase of the information exchanged. Then, we propose an “experimental” implementation of a 1-dimensional communication channel based on a Hamiltonian system, and calculate the actual rate with which information is exchanged between the first and last particle of the channel. Finally, a relation between our results and important quantities of thermodynamics is presented. PMID:24586891

  16. Automatic graphene transfer system for improved material quality and efficiency.

    PubMed

    Boscá, Alberto; Pedrós, Jorge; Martínez, Javier; Palacios, Tomás; Calle, Fernando

    2016-01-01

    In most applications based on chemical vapor deposition (CVD) graphene, the transfer from the growth to the target substrate is a critical step for the final device performance. Manual procedures are time consuming and depend on handling skills, whereas existing automatic roll-to-roll methods work well for flexible substrates but tend to induce mechanical damage in rigid ones. A new system that automatically transfers CVD graphene to an arbitrary target substrate has been developed. The process is based on the all-fluidic manipulation of the graphene to avoid mechanical damage, strain and contamination, and on the combination of capillary action and electrostatic repulsion between the graphene and its container to ensure a centered sample on top of the target substrate. The improved carrier mobility and yield of the automatically transferred graphene, as compared to that manually transferred, is demonstrated by the optical and electrical characterization of field-effect transistors fabricated on both materials. In particular, 70% higher mobility values, with a 30% decrease in the unintentional doping and a 10% strain reduction are achieved. The system has been developed for lab-scale transfer and proved to be scalable for industrial applications. PMID:26860260

  17. Automatic graphene transfer system for improved material quality and efficiency

    PubMed Central

    Boscá, Alberto; Pedrós, Jorge; Martínez, Javier; Palacios, Tomás; Calle, Fernando

    2016-01-01

    In most applications based on chemical vapor deposition (CVD) graphene, the transfer from the growth to the target substrate is a critical step for the final device performance. Manual procedures are time consuming and depend on handling skills, whereas existing automatic roll-to-roll methods work well for flexible substrates but tend to induce mechanical damage in rigid ones. A new system that automatically transfers CVD graphene to an arbitrary target substrate has been developed. The process is based on the all-fluidic manipulation of the graphene to avoid mechanical damage, strain and contamination, and on the combination of capillary action and electrostatic repulsion between the graphene and its container to ensure a centered sample on top of the target substrate. The improved carrier mobility and yield of the automatically transferred graphene, as compared to that manually transferred, is demonstrated by the optical and electrical characterization of field-effect transistors fabricated on both materials. In particular, 70% higher mobility values, with a 30% decrease in the unintentional doping and a 10% strain reduction are achieved. The system has been developed for lab-scale transfer and proved to be scalable for industrial applications. PMID:26860260

  18. Automatic graphene transfer system for improved material quality and efficiency

    NASA Astrophysics Data System (ADS)

    Boscá, Alberto; Pedrós, Jorge; Martínez, Javier; Palacios, Tomás; Calle, Fernando

    2016-02-01

    In most applications based on chemical vapor deposition (CVD) graphene, the transfer from the growth to the target substrate is a critical step for the final device performance. Manual procedures are time consuming and depend on handling skills, whereas existing automatic roll-to-roll methods work well for flexible substrates but tend to induce mechanical damage in rigid ones. A new system that automatically transfers CVD graphene to an arbitrary target substrate has been developed. The process is based on the all-fluidic manipulation of the graphene to avoid mechanical damage, strain and contamination, and on the combination of capillary action and electrostatic repulsion between the graphene and its container to ensure a centered sample on top of the target substrate. The improved carrier mobility and yield of the automatically transferred graphene, as compared to that manually transferred, is demonstrated by the optical and electrical characterization of field-effect transistors fabricated on both materials. In particular, 70% higher mobility values, with a 30% decrease in the unintentional doping and a 10% strain reduction are achieved. The system has been developed for lab-scale transfer and proved to be scalable for industrial applications.

  19. Treatment of continuum in nuclear reactions involving weakly bound systems. A simple model to test different prescriptions describing the coupling to continuum states

    SciTech Connect

    Dasso, C. H.; Vitturi, A.

    2009-03-04

    We exploit a model describing the break-up of weakly-bound nuclei that can be used as a laboratory for testing different prescriptions that have been advanced in the literature to take into account the near-by presence of continuum states. In the model we follow the evolution of a single particle wave function in one dimension, initially bound by a Woods-Saxon type potential and then perturbed by a time- and position-dependent external field. Proper choices of this potential can simulate the effect of the interaction between reaction partners in a nuclear collision. These processes generate inelastic excitation probabilities that--distributed over the bound and continuum states of the system--lead to either a partial or a total fragmentation of the final wave function. The comparison with the exact calculations shows that standard coupled channel descriptions based on discretization of the continuum can be accurate only when a proper choice is made of the number of discrete states, of the energy mesh and of the energy cutoff. This may imply, even in simplified cases, the use of a rather large (and unpracticable) number of channels. The use of a more restricted number of channels may lead to misleading results.

  20. Transfer of Instrument Training and the Synthetic Flight Training System.

    ERIC Educational Resources Information Center

    Caro, Paul W.

    One phase of an innovative flight training program, its development, and initial administration is described in this paper. The operational suitability test activities related to a determination of the transfer of instrument training value of the Army's Synthetic Flight Training System (SFTS) Device 2B24. Sixteen active Army members of an Officer…

  1. 40 CFR 63.689 - Standards: Transfer systems.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... transfer system is designed and operated such that an internal pressure in the vapor headspace in the enclosure is maintained at a level less than atmospheric pressure when the control device is operating, and... standards specified in 40 CFR part 63, subpart RR—National Emission Standards for Individual Drain...

  2. Migrant Student Record Transfer System in New York State.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of Migrant Education.

    In 1970, the Migrant Student Record Transfer System (MSRTS) was funded through Title I of the Elementary and Secondary Education Act. A single center at Little Rock (Arkansas) was designed to contain a profile on each migrant student enrolled. The Center's aim was to assure a high degree of accuracy while maintaining flexibility and ready access…

  3. An Introduction to Register Transfer Level Simulation of Digital Systems.

    ERIC Educational Resources Information Center

    Hemming, Cliff; Smith R. J., II

    Register transfer level (RTL) descriptions of digital systems have certain advantages over other descriptive techniques, especially during early phases of the design effort. There are at least three identifiable major uses for RTL-type descriptions. First, RTL can serve as documentation of digital processor behavior, recording in a concise fashion…

  4. Putting Dreyfus into Action: The European Credit Transfer System

    ERIC Educational Resources Information Center

    Markowitsch, Jorg; Luomi-Messerer, Karin; Becker, Matthias; Spottl, Georg

    2008-01-01

    Purpose: The purpose of this article is to look closely at the development of a European Credit Transfer System for Vocational Education and Training (ECVET). The European Commission, together with the member States, are working on it and several pilot projects have been initiated within the Leonardo da Vinci Programme of the European Commission.…

  5. 40 CFR 63.689 - Standards: Transfer systems.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... transfer system is designed and operated such that an internal pressure in the vapor headspace in the enclosure is maintained at a level less than atmospheric pressure when the control device is operating, and... standards specified in 40 CFR part 63, subpart RR—National Emission Standards for Individual Drain...

  6. West Valley transfer cart control system design description

    SciTech Connect

    Bradley, E.C.; Crutcher, R.I.; Halliwell, J.W.; Hileman, M.S.; Moore, M.R.; Nodine, R.N.; Ruppel, F.R.; Vandermolen, R.I.

    1993-01-01

    Detail design of the control system for the West Valley Nuclear Services Vitrification Facility transfer cart has been completed by Oak Ridge National Laboratory. This report documents the requirements and describes the detail design of that equipment and control software. Copies of significant design documents including analysis and testing reports and design drawings are included in the Appendixes.

  7. Automated gas transfer systems for low pressure operations

    SciTech Connect

    Baker, R.W.; Hoseus, N.L.

    1988-01-22

    The introduction of new components and the modification of commercially available hardware have been instrumental in the automation of low pressure gas transfer systems. The benefits from the automation have been faster sample operation, increased precision and a safer environment for the operator.

  8. A Primer on Prescription Drug Abuse and the Role of the Pharmacy Director.

    PubMed

    Harvin, Andre; Weber, Robert J

    2015-05-01

    Prescription drug abuse, or using a prescription drug in a way not intended by the provider, has become such an issue in the United States that in 2013 the US Department of Health and Human Services (HHS) and the Centers for Disease Control and Prevention (CDC) classified it as a new epidemic. The goal of this article is to provide pharmacy directors with a primer on prescription drug abuse and its prevention. This article will cover the causes and societal impact of prescription drug abuse, review recent and proposed strategies to prevent prescription drug abuse, and discuss efforts within the health system to reduce the risks of narcotic diversion that can lead to prescription drug abuse. There are several health and societal factors that have contributed to the rise in prescription drug abuse. As there is no singular contributory factor to this epidemic, there is no easy solution for proper containment and monitoring of prescription drug use. Pharmacy directors play a vital role in the safe use of prescription medications by providing for fail-safe systems for accounting and controlling prescription drugs. In addition, pharmacists can play a role in educating patients and health care workers on the dangers of prescription drug abuse. Health systems should form teams to identify drug diversion and provide an intervention that demands accountability while helping the impaired professional. Health system pharmacy directors must play an integral role in these efforts and continue to seek opportunities to reduce any risks for prescription drug abuse. PMID:26405329

  9. Omnidirectional wireless power transfer system supporting mobile devices

    NASA Astrophysics Data System (ADS)

    Che, Bang-Jun; Meng, Fan-Yi; Lyu, Yue-Long; Zhu, Wen-Liang; Zhang, Kuang; Yang, Guo-Hui; Fu, Jia-Hui; Zhu, Lei; Wu, Qun; Sun, Li

    2016-02-01

    An efficient method for the challenge design of an omnidirectional wireless power transfer system (OWPT) is proposed. The OWPT is realized utilizing the rotating magnetic field, which is generated by the proposed 2-D transmitter. The transmitter is composed by two mutually perpendicular loops fed by two excitation sources with the same magnitude and 90° phase difference. An OWPT system prototype is fabricated and measured. Experimental results demonstrate that the system can deliver power to receivers moving around the transmitter with a steady transfer efficiency. Furthermore, the magnitude distribution of the rotating magnetic field can be controlled by the feeding phase difference between the two loops. This capability enables the OWPT system to focus energy for device moving in a limited receiving angle range.

  10. Quartz microbalance device for transfer into ultrahigh vacuum systems

    SciTech Connect

    Stavale, F.; Achete, C. A.; Niehus, H.

    2008-10-15

    An uncomplicated quartz microbalance device has been developed which is transferable into ultrahigh vacuum (UHV) systems. The device is extremely useful for flux calibration of different kinds of material evaporators. Mounted on a commercial specimen holder, the device allows fast quartz microbalance transfer into the UHV and subsequent positioning exactly to the sample location where subsequent thin film deposition experiments shall be carried out. After backtransfer into an UHV sample stage, the manipulator may be loaded in situ with the specimen suited for the experiment. The microbalance device capability is demonstrated for monolayer and submonolayer vanadium depositions with an achieved calibration sensitivity of less the 0.001 ML coverage.

  11. How Can Geographical Information Systems and Spatial Analysis Inform a Response to Prescription Opioid Misuse? A Discussion in the Context of Existing Literature.

    PubMed

    Mazumdar, Soumya; Mcrae, Ian S; Islam, M Mofizul

    2015-01-01

    The misuse of prescription opioids is a major public health problem in the United States, Canada, Australia and other parts of the developed world. Methods to quantify dimensions of the risk environment in relation to drug usage and law enforcement that are both structural and spatial, draw geography into traditional public health research even though there has been limited attempt to address the prescription opioid misuse problem from a geographic perspective. We discuss how geographic technologies can be utilized to study the landscape of prescription opioids and similar drugs, and target appropriate health services interventions. We use examples drawn from various jurisdictions to present our case and highlight through these examples how a geospatial perspective can help support research on prescription opioid misuse. The prescription drug misuse landscape can be studied through examination of the domains of demand, supply, harms and harm reduction. We discuss how each of these domains can benefit from a local geographic perspective, and subsequent geographic exploration and analyses. PMID:26452451

  12. Using Genes to Guide Prescriptions

    MedlinePlus

    ... Science > Using Genes to Guide Prescriptions Inside Life Science View All Articles | Inside Life Science Home Page Using Genes to Guide Prescriptions By ... to Zoloft: Ways Medicines Work This Inside Life Science article also appears on LiveScience . Learn about related ...

  13. Hubble Space Telescope prescription retrieval.

    PubMed

    Redding, D; Dumont, P; Yu, J

    1993-04-01

    Prescription retrieval is a technique for directly estimating optical prescription parameters from images. We apply it to estimate the value of the Hubble Space Telescope primary mirror conic constant. Our results agree with other studies that examined primary-mirror test fixtures and results. In addition they show that small aberrations exist on the planetary-camera repeater optics.

  14. Adolescent Nonmedical Prescription Drug Use

    ERIC Educational Resources Information Center

    Ford, Jason A.; Watkins, William C.

    2012-01-01

    For many adolescents today, the most common form of substance use is nonmedical prescription drug use. Fittingly, many researchers, policy makers, and people who work with youth are concerned about the serious problems associated with nonmedical prescription drug use (NMPDU). In this article, authors Jason Ford and William Watkins provide an…

  15. Qualitative Assertions as Prescriptive Statements

    ERIC Educational Resources Information Center

    Nolen, Amanda; Talbert, Tony

    2011-01-01

    The primary question regarding prescriptive appropriateness is a difficult one to answer for the qualitative researcher. While there are certainly qualitative researchers who have offered prescriptive protocols to better define and describe the terrain of qualitative research design and there are qualitative researchers who offer research…

  16. 21 CFR 201.120 - Prescription chemicals and other prescription components.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Prescription chemicals and other prescription... Prescription chemicals and other prescription components. A drug prepared, packaged, and primarily sold as a prescription chemical or other component for use by registered pharmacists in compounding prescriptions or...

  17. 21 CFR 201.120 - Prescription chemicals and other prescription components.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Prescription chemicals and other prescription... Prescription chemicals and other prescription components. A drug prepared, packaged, and primarily sold as a prescription chemical or other component for use by registered pharmacists in compounding prescriptions or...

  18. Prescription Drug Diversion: Predictors of Illicit Acquisition and Redistribution in Three U.S. Metropolitan Areas

    PubMed Central

    Harris, Shana; Nikulina, Valentina; Gelpí-Acosta, Camila; Morton, Cory; Newsome, Valerie; Gunn, Alana; Hoefinger, Heidi; Aikins, Ross; Smith, Vivian; Barry, Victoria; Downing, Martin J.

    2015-01-01

    Objective Prescription drug diversion, the transfer of prescription drugs from lawful to unlawful channels for distribution or use, is a problem in the United States. Despite the pervasiveness of diversion, there are gaps in the literature regarding characteristics of individuals who participate in the illicit trade of prescription drugs. This study examines a range of predictors (e.g., demographics, prescription insurance coverage, perceived risk associated with prescription drug diversion) of membership in three distinct diverter groups: individuals who illicitly acquire prescription drugs, those who redistribute them, and those who engage in both behaviors. Methods Data were drawn from a cross-sectional Internet study (N = 846) of prescription drug use and diversion patterns in New York City, South Florida, and Washington, D.C.. Participants were classified into diversion categories based on their self-reported involvement in the trade of prescription drugs. Group differences in background characteristics of diverter groups were assessed by Chi-Square tests and followed up with multivariate logistic regressions. Results While individuals in all diversion groups were more likely to be younger and have a licit prescription for any of the assessed drugs in the past year than those who did not divert, individuals who both acquire and redistribute are more likely to live in New York City, not have prescription insurance coverage, and perceive fewer legal risks of prescription drug diversion. Conclusion Findings suggest that predictive characteristics vary according to diverter group. PMID:26690813

  19. Documentation requirements for Applications Systems Verification and Transfer projects (ASVTs)

    NASA Technical Reports Server (NTRS)

    Suchy, J. T.

    1977-01-01

    NASA's Application Systems Verification and Transfer Projects (ASVTs) are deliberate efforts to facilitate the transfer of applications of NASA-developed space technology to users such as federal agencies, state and local governments, regional planning groups, public service institutions, and private industry. This study focused on the role of documentation in facilitating technology transfer both to primary users identified during project planning and to others with similar information needs. It was understood that documentation can be used effectively when it is combined with informal (primarily verbal) communication within each user community and with other formal techniques such as organized demonstrations and training programs. Documentation examples from eight ASVT projects and one potential project were examined to give scope to the investigation.

  20. Pneumatic Regolith Transfer Systems for In-Situ Resource Utilization

    NASA Technical Reports Server (NTRS)

    Mueller, Robert P.; Townsend, Ivan I., III; Mantovani, James G.

    2010-01-01

    One aspect of In-Situ Resource Utilization (lSRU) in a lunar environment is to extract oxygen and other elements from the minerals that make up the lunar regolith. Typical ISRU oxygen production processes include but are not limited to hydrogen reduction, carbothermal and molten oxide electrolysis. All of these processes require the transfer of regolith from a supply hopper into a reactor for chemical reaction processing, and the subsequent extraction of the reacted regolith from the reactor. This paper will discuss recent activities in the NASA ISRU project involved with developing pneumatic conveying methods to achieve lunar regolith simulant transfer under I-g and 1/6-g gravitational environments. Examples will be given of hardware that has been developed and tested by NASA on reduced gravity flights. Lessons learned and details of pneumatic regolith transfer systems will be examined as well as the relative performance in a 1/6th G environment

  1. Ginseng in Traditional Herbal Prescriptions

    PubMed Central

    Park, Ho Jae; Kim, Dong Hyun; Park, Se Jin; Kim, Jong Min; Ryu, Jong Hoon

    2012-01-01

    Panax ginseng Meyer has been widely used as a tonic in traditional Korean, Chinese, and Japanese herbal medicines and in Western herbal preparations for thousands of years. In the past, ginseng was very rare and was considered to have mysterious powers. Today, the efficacy of drugs must be tested through well-designed clinical trials or meta-analyses, and ginseng is no exception. In the present review, we discuss the functions of ginseng described in historical documents and describe how these functions are taken into account in herbal prescriptions. We also discuss the findings of experimental pharmacological research on the functions of ginseng in ginseng-containing prescriptions and how these prescriptions have been applied in modern therapeutic interventions. The present review on the functions of ginseng in traditional prescriptions helps to demystify ginseng and, as a result, may contribute to expanding the use of ginseng or ginseng-containing prescriptions. PMID:23717123

  2. A consistent prescription of stratospheric aerosol for both radiation and chemistry in the Community Earth System Model (CESM1)

    NASA Astrophysics Data System (ADS)

    Reynolds Neely, Ryan, III; Conley, Andrew J.; Vitt, Francis; Lamarque, Jean-François

    2016-07-01

    Here we describe an updated parameterization for prescribing stratospheric aerosol in the National Center for Atmospheric Research (NCAR) Community Earth System Model (CESM1). The need for a new parameterization is motivated by the poor response of the CESM1 (formerly referred to as the Community Climate System Model, version 4, CCSM4) simulations contributed to the Coupled Model Intercomparison Project 5 (CMIP5) to colossal volcanic perturbations to the stratospheric aerosol layer (such as the 1991 Pinatubo eruption or the 1883 Krakatau eruption) in comparison to observations. In particular, the scheme used in the CMIP5 simulations by CESM1 simulated a global mean surface temperature decrease that was inconsistent with the GISS Surface Temperature Analysis (GISTEMP), NOAA's National Climatic Data Center, and the Hadley Centre of the UK Met Office (HADCRUT4). The new parameterization takes advantage of recent improvements in historical stratospheric aerosol databases to allow for variations in both the mass loading and size of the prescribed aerosol. An ensemble of simulations utilizing the old and new schemes shows CESM1's improved response to the 1991 Pinatubo eruption. Most significantly, the new scheme more accurately simulates the temperature response of the stratosphere due to local aerosol heating. Results also indicate that the new scheme decreases the global mean temperature response to the 1991 Pinatubo eruption by half of the observed temperature change, and modelled climate variability precludes statements as to the significance of this change.

  3. Triplet-Triplet Energy Transfer Study in Hydrogen Bonding Systems.

    PubMed

    Wang, Zhijia; Zhao, Jianzhang; Guo, Song

    2015-01-01

    The 2,6-diiodoBodipy-styrylBodipy hydrogen bonding system was prepared to study the effect of hydrogen bonding on the triplet-triplet-energy-transfer (TTET) process. 2,6-DiiodoBodipy linked with N-acetyl-2,6-diaminopyridine (D-2) was used as the triplet energy donor, and the styrylBodipy connected with thymine (A-1) was used as triplet energy acceptor, thus the TTET process was established upon photoexcitation. The photophysical processes of the hydrogen bonding system were studied with steady-state UV-vis absorption spectroscopy, fluorescence spectroscopy, fluorescence lifetime measurement and nanosecond time-resolved transient absorption spectroscopies. The TTET of the intramolecular/hydrogen bonding/intermolecular systems were compared through nanosecond transient absorption spectroscopy. The TTET process of the hydrogen bonding system is faster and more efficient (kTTET = 6.9 × 10(4) s(-1), ΦTTET = 94.0%) than intermolecular triplet energy transfer (kTTET = 6.0 × 10(4) s(-1), ΦTTET = 90.9%), but slower and less efficient than intramolecular triplet energy transfer (kTTET > 10(8) s(-1)). These results are valuable for designing self-assembly triplet photosensitizers and for the study of the TTET process of hydrogen bonding systems.

  4. Saponification reaction system: a detailed mass transfer coefficient determination.

    PubMed

    Pečar, Darja; Goršek, Andreja

    2015-01-01

    The saponification of an aromatic ester with an aqueous sodium hydroxide was studied within a heterogeneous reaction medium in order to determine the overall kinetics of the selected system. The extended thermo-kinetic model was developed compared to the previously used simple one. The reaction rate within a heterogeneous liquid-liquid system incorporates a chemical kinetics term as well as mass transfer between both phases. Chemical rate constant was obtained from experiments within a homogeneous medium, whilst the mass-transfer coefficient was determined separately. The measured thermal profiles were then the bases for determining the overall reaction-rate. This study presents the development of an extended kinetic model for considering mass transfer regarding the saponification of ethyl benzoate with sodium hydroxide within a heterogeneous reaction medium. The time-dependences are presented for the mass transfer coefficient and the interfacial areas at different heterogeneous stages and temperatures. The results indicated an important role of reliable kinetic model, as significant difference in k(L)a product was obtained with extended and simple approach.

  5. Heat transfer in vertically aligned phase change energy storage systems

    SciTech Connect

    El-Dessouky, H.T.; Bouhamra, W.S.; Ettouney, H.M.; Akbar, M.

    1999-05-01

    Convection effects on heat transfer are analyzed in low temperature and vertically aligned phase change energy storage systems. This is performed by detailed temperature measurements in the phase change material (PCM) in eighteen locations forming a grid of six radial and three axial positions. The system constitutes a double pipe configuration, where commercial grade paraffin wax is stored in the annular space between the two pipes and water flows inside the inner pipe. Vertical alignment of the system allowed for reverse of the flow direction of the heat transfer fluid (HTF), which is water. Therefore, the PCM is heated from the bottom for HTF flow from bottom to top and from the top as the HTF flow direction is reversed. For the former case, natural convection affects the melting process. Collected data are used to study variations in the transient temperature distribution at axial and radial positions as well as for the two-dimensional temperature field. The data are used to calculate the PCM heat transfer coefficient and to develop correlations for the melting Fourier number. Results indicate that the PCM heat transfer coefficient is higher for the case of PCM heating from bottom to top. Nusselt number correlations are developed as a function of Rayleigh, Stefan, and Fourier numbers for the HTF flow from bottom to top and as a function of Stefan and Fourier numbers for HTF flow from top to bottom. The enhancement ratio for heat transfer caused by natural convection increases and then levels off as the inlet temperature of the HTF is increased.

  6. On identifying transfer functions and state equations for linear systems.

    NASA Technical Reports Server (NTRS)

    Shieh, L. S.; Chen, C. F.; Huang, C. J.

    1972-01-01

    Two methods are established for identifying constant-coefficient, C to the 2n power type of noise-free linear systems if the time response data of the input-output or of all states are known. 2n response data are required to identify an nth-order transfer function or state equation for an unknown linear system. The order of the unknown system can be identified by checking a sequence of determinants. The Z transform and its inversion are mainly used.

  7. Technology of H-II Transfer Vehicle Rendezvous System

    NASA Astrophysics Data System (ADS)

    Kasai, Toru; Ueda, Satoshi; Uematsu, Hirohiko

    The H-II Transfer Vehicle (HTV), which is a Japanese unmanned cargo transfer spacecraft, will deliver supplies to the International Space Station (ISS). The first HTV will be launched in 2009 from the Tanegashima Space Center aboard an H-IIB launch vehicle with up to 6,000kg of supplies. HTV approaches to the ISS and the Space Station Remote Manipulator System (SSRMS), known as Canadarm2, will grapple the HTV and berth it to the ISS. After the supplies, the HTV will then be loaded with waste materials and then separated from the ISS by SSRMS. HTV conducts departure sequence from ISS after release from SSRMS and reentry to the atmosphere. In this paper, technology of HTV automated Guidance, Navigation and Control (GN&C) system is presented.

  8. Use of influence diagrams in gas transfer system option prioritization

    SciTech Connect

    Heger, A.S.; Garcia, M.D.

    1995-08-01

    A formal decision-analysis methodology was applied to aid the Department of Energy (DOE) in deciding which of several gas transfer system (GTS) options should be selected. The decision objectives for this case study, i.e., risk and cost, were directly derived from the DOE guidelines. Influence diagrams were used to define the structure of the decision problem and clearly delineate the flow if information. A set of performance matrices wee used in conjunction with the influence diagrams to assess and evaluate the degree to which the objectives of the case study were met. These performance measures were extracted from technical models, design and operating data, and professional judgments. The results were aggregated to provide an overall evaluation of the different design options of the gas transfer system. Consequently, the results of this analysis were used as an aid to DOE to select a viable GTS option.

  9. The Role of a Computer-Managed Instructional System's Prescriptive Curriculum in the Basic Skill Areas of Math and Reading Scores for Correctional Pre-Trial Detainees (Inmates).

    ERIC Educational Resources Information Center

    Winters, Clyde Ahmad; And Others

    1993-01-01

    Results of a study of methods for the remediation of incarcerated adult students basic skill deficiencies indicated that a program that integrates the Test of Adult Basic Education assessment and evaluation, an individual educational prescriptive curriculum, computer-aided instruction, and direct instruction by correctional facilitators is most…

  10. Pneumatic Regolith Transfer Systems for In Situ Resource Utilization

    NASA Technical Reports Server (NTRS)

    Mueller, R. P.; Townsend, I. I.; Mantovani, J. G.; Zacny, Kris A.; Craft, Jack

    2010-01-01

    This slide presentation reviews the testing of a pneumatic system for transfering regolith, to be used for In Situ Resource Utilization (ISRU). Using both the simulated microgravity of parabolic flight and ground testing, the tests demonstrated that lunar regolith can be conveyed pneumatically into a simulated ISRU oxygen production plant reactor. The ground testing also demonstrated that the regolith can be expelled from the ISRU reactor for disposal or for other resource processing.

  11. Development of the prototype pneumatic transfer system for ITER neutron activation system.

    PubMed

    Cheon, M S; Seon, C R; Pak, S; Lee, H G; Bertalot, L

    2012-10-01

    The neutron activation system (NAS) measures neutron fluence at the first wall and the total neutron flux from the ITER plasma, providing evaluation of the fusion power for all operational phases. The pneumatic transfer system (PTS) is one of the key components of the NAS for the proper operation of the system, playing a role of transferring encapsulated samples between the capsule loading machine, irradiation stations, counting stations, and disposal bin. For the validation and the optimization of the design, a prototype of the PTS was developed and capsule transfer tests were performed with the developed system.

  12. Emergency flight control system using one engine and fuel transfer

    NASA Technical Reports Server (NTRS)

    Burcham, Jr., Frank W. (Inventor); Burken, John J. (Inventor); Le, Jeanette (Inventor)

    2000-01-01

    A system for emergency aircraft control uses at least one engine and lateral fuel transfer that allows a pilot to regain control over an aircraft under emergency conditions. Where aircraft propulsion is available only through engines on one side of the aircraft, lateral fuel transfer provides means by which the center of gravity of the aircraft can be moved over to the wing associated with the operating engine, thus inducing a moment that balances the moment from the remaining engine, allowing the pilot to regain control over the aircraft. By implementing the present invention in flight control programming associated with a flight control computer (FCC), control of the aircraft under emergency conditions can be linked to the yoke or autopilot knob of the aircraft. Additionally, the center of gravity of the aircraft can be shifted in order to effect maneuvers and turns by spacing such center of gravity either closer to or farther away from the propelling engine or engines. In an alternative embodiment, aircraft having a third engine associated with the tail section or otherwise are accommodated and implemented by the present invention by appropriately shifting the center of gravity of the aircraft. Alternatively, where a four-engine aircraft has suffered loss of engine control on one side of the plane, the lateral fuel transfer may deliver the center of gravity closer to the two remaining engines. Differential thrust between the two can then control the pitch and roll of the aircraft in conjunction with lateral fuel transfer.

  13. Usefulness of traditionally defined herbal properties for distinguishing prescriptions of traditional Chinese medicine from non-prescription recipes.

    PubMed

    Ung, C Y; Li, H; Kong, C Y; Wang, J F; Chen, Y Z

    2007-01-01

    Traditional Chinese medicine (TCM) has been widely practiced and is considered as an attractive to conventional medicine. Multi-herb recipes have been routinely used in TCM. These have been formulated by using TCM-defined herbal properties (TCM-HPs), the scientific basis of which is unclear. The usefulness of TCM-HPs was evaluated by analyzing the distribution pattern of TCM-HPs of the constituent herbs in 1161 classical TCM prescriptions, which shows patterns of multi-herb correlation. Two artificial intelligence (AI) methods were used to examine whether TCM-HPs are capable of distinguishing TCM prescriptions from non-TCM recipes. Two AI systems were trained and tested by using 1161 TCM prescriptions, 11,202 non-TCM recipes, and two separate evaluation methods. These systems correctly classified 83.1-97.3% of the TCM prescriptions, 90.8-92.3% of the non-TCM recipes. These results suggest that TCM-HPs are capable of separating TCM prescriptions from non-TCM recipes, which are useful for formulating TCM prescriptions and consistent with the expected correlation between TCM-HPs and the physicochemical properties of herbal ingredients responsible for producing the collective pharmacological and other effects of specific TCM prescriptions. PMID:16884871

  14. Prescription drugs: issues of cost, coverage, and quality.

    PubMed

    Copeland, C

    1999-04-01

    This Issue Brief closely examines expenditures on prescription drugs, and discusses their potential to substitute for other types of health care services. In addition, it describes employer coverage of prescription drugs, direct-to-consumer advertising of prescription drugs, and potential legislation affecting the prescription drug market. Prescription drug expenditures grew at double-digit rates during almost every year since 1980, accelerating to 14.1 percent in 1997. In contrast, total national health expenditures, hospital service expenditures, and physician service expenditures growth rates decreased from approximately 13 percent in 1980 to less than 5 percent in 1997. Private insurance payments for prescription drugs increased 17.7 percent in 1997, after growing 22.1 percent in 1995 and 18.3 percent in 1996. This growth in prescription drug payments compares with 4 percent or less overall annual growth in private insurance payments for each of those three years. From 1993 to 1997, the overwhelming majority of the increases in expenditures on prescription drugs were attributable to increased volume, mix, and availability of pharmaceutical products. In 1997, these factors accounted for more than 80 percent of the growth in prescription drug expenditures. A leading explanation for the sharp growth in drug expenditures is that prescription drugs are a substitute for other forms of health care. While it is difficult to determine the extent to which this substitution occurs, various studies have associated cost savings with the use of pharmaceutical products in treating specific diseases. Evidence suggests that more appropriate utilization of prescription drugs has the potential to lower total expenditures and improve the quality of care. Also, some studies indicate the U.S. health care system needs to improve the way patients use and physicians prescribe current medications. Prescription drug plans offered by employers are likely to undergo changes to ensure that

  15. Research Reports: Prescription Drug Abuse

    MedlinePlus

    ... Trends and Alerts Alcohol Club Drugs Cocaine Hallucinogens Heroin Inhalants Marijuana MDMA (Ecstasy/Molly) Methamphetamine Opioids Prescription ... since 1999, and by 2007, outnumbered those involving heroin and cocaine. NIDA hopes to change this situation ...

  16. Specific Gene Repression by CRISPRi System Transferred through Bacterial Conjugation

    PubMed Central

    2014-01-01

    In microbial communities, bacterial populations are commonly controlled using indiscriminate, broad range antibiotics. There are few ways to target specific strains effectively without disrupting the entire microbiome and local environment. Here, we use conjugation, a natural DNA horizontal transfer process among bacterial species, to deliver an engineered CRISPR interference (CRISPRi) system for targeting specific genes in recipient Escherichia coli cells. We show that delivery of the CRISPRi system is successful and can specifically repress a reporter gene in recipient cells, thereby establishing a new tool for gene regulation across bacterial cells and potentially for bacterial population control. PMID:25409531

  17. RELAP5 MODEL OF THE DIVERTOR PRIMARY HEAT TRANSFER SYSTEM

    SciTech Connect

    Popov, Emilian L; Yoder Jr, Graydon L; Kim, Seokho H

    2010-08-01

    This report describes the RELAP5 model that has been developed for the divertor primary heat transfer system (PHTS). The model is intended to be used to examine the transient performance of the divertor PHTS and evaluate control schemes necessary to maintain parameters within acceptable limits during transients. Some preliminary results are presented to show the maturity of the model and examine general divertor PHTS transient behavior. The model can be used as a starting point for developing transient modeling capability, including control system modeling, safety evaluations, etc., and is not intended to represent the final divertor PHTS design. Preliminary calculations using the models indicate that during normal pulsed operation, present pressurizer controls may not be sufficient to keep system pressures within their desired range. Additional divertor PHTS and control system design efforts may be required to ensure system pressure fluctuation during normal operation remains within specified limits.

  18. Mass transfer in binary X-ray systems

    NASA Technical Reports Server (NTRS)

    Mccray, R.; Hatchett, S.

    1975-01-01

    The influence of X-ray heating on gas flows in binary X-ray systems is examined. A simple estimate is obtained for the evaporative wind flux from a stellar atmosphere due to X-ray heating which agrees with numerical calculations by Alme and Wilson (1974) but disagrees with calculations by Arons (1973) and by Basko and Sunyaev (1974) for the Her X-1/HZ Her system. The wind flux is sensitive to the soft X-ray spectrum. The self-excited wind mechanism does not work. Mass transfer in the Hercules system probably occurs by flow of the atmosphere of HZ Her through the gravitational saddle point of the system. The accretion gas stream is probably opaque with atomic density of not less than 10 to the 15th power per cu cm and is confined to a small fraction of 4(pi) steradians. Other binary X-ray systems are briefly discussed.

  19. Improved power transfer to wearable systems through stretchable magnetic composites

    NASA Astrophysics Data System (ADS)

    Lazarus, N.; Bedair, S. S.

    2016-05-01

    The use of wireless power transfer is common in stretchable electronics since physical wiring can be easily destroyed as the system is stretched. This work presents the first demonstration of improved inductive power coupling to a stretchable system through the addition of a thin layer of ferroelastomeric material. A ferroelastomer, an elastomeric polymer loaded with magnetic particulates, has a permeability greater than one while retaining the ability to survive significant mechanical strains. A recently developed ferroelastomer composite based on sendust platelets within a soft silicone elastomer was incorporated into liquid metal stretchable inductors based on the liquid metal galinstan in fluidic channels. For a single-turn inductor, the maximum power transfer efficiency rises from 71 % with no backplane, to 81 % for a rigid ferrite backplane on the transmitter side alone, to 86 % with a ferroelastomer backplane on the receiver side as well. The coupling between a commercial wireless power transmitter coil with ferrite backplane to a five-turn liquid metal inductor was also investigated, finding an improvement in power transfer efficiency from 81 % with only a rigid backplane to 90 % with the addition of the ferroelastomer backplane. Both the single and multi-turn inductors were demonstrated surviving up to 50 % uniaxial applied strain.

  20. Simplified Simulation of Mass Transfer in Double White Dwarf Systems

    NASA Astrophysics Data System (ADS)

    Vannah, Sara; Frank, Juhan

    2016-01-01

    The behavior both stable and unstable mass transfer in semi-detached double white dwarfs triggers a cornucopia of astrophysical phenomena including Type Ia supernovae and AM CVn stars. Current 3D hydrodynamic simulations of the evolution these systems following the mass transfer, binary orbital parameters, and the self-consistent gravitational field over several tens of orbital periods have produced a wealth of data. However, these simulations can take weeks to months in high-performance computing platforms to execute. To help with the interpretation of results of such large scale simulations, and to enable a quick exploration of binary parameter space, we have developed a Mathematica code that integrates forward in time a system of 5 ODEs describing the orbit-averaged evolution of the binary separation as well as the radius, mass, and spin angular momentum of both components of the binary. By adjusting a few parameters describing the mass transfer as a function of the Roche-lobe overflow and the strength of the tidal coupling between the orbit and component spins we are able to obtain approximate fits to previously run hydrodynamic simulations. This simplified simulation is able to run simulations similar to the hydrodynamic versions in a matter of seconds on a dual-core PC or Mac computer.

  1. Situ soil sampling probe system with heated transfer line

    DOEpatents

    Robbat, Jr., Albert

    2002-01-01

    The present invention is directed both to an improved in situ penetrometer probe and to a heated, flexible transfer line. The line and probe may be implemented together in a penetrometer system in which the transfer line is used to connect the probe to a collector/analyzer at the surface. The probe comprises a heater that controls a temperature of a geologic medium surrounding the probe. At least one carrier gas port and vapor collection port are located on an external side wall of the probe. The carrier gas port provides a carrier gas into the geologic medium, and the collection port captures vapors from the geologic medium for analysis. In the transfer line, a flexible collection line that conveys a collected fluid, i.e., vapor, sample to a collector/analyzer. A flexible carrier gas line conveys a carrier gas to facilitate the collection of the sample. A system heating the collection line is also provided. Preferably the collection line is electrically conductive so that an electrical power source can generate a current through it so that the internal resistance generates heat.

  2. [Inappropriate prescription in older patients: the STOPP/START criteria].

    PubMed

    Delgado Silveira, Eva; Muñoz García, María; Montero Errasquin, Beatriz; Sánchez Castellano, Carmen; Gallagher, Paul F; Cruz-Jentoft, Alfonso J

    2009-01-01

    Older people are a heterogeneous group of patients, often with multiple comorbidities for which they are prescribed a large number of drugs, leading to an increased risk of adverse drug reactions (ADR) and drug interactions. This risk is compounded by physiological age-related changes in physiology, changes in drug pharmacokinetics and pharmacodynamics, as well as by disease-related, functional and social issues. Inappropriate prescription of drugs is common in the older individuals and contributes to the increased risk of ADR. Several tools have been developed to detect potentially inappropriate prescription, the most frequently used in Spain being Beers' criteria. However, the value of these criteria is limited, especially as they were developed in a different healthcare system. In this article, the Spanish version of a new tool to detect potentially inappropriate prescriptions-STOPP (Screening Tool of Older Person's Prescriptions) and START (Screening Tool to Alert doctors to Right i.e. appropriate, indicated Treatment) criteria-is presented. The creation, development, reliability, and use of these criteria in routine practice is described and discussed. These criteria have shown better sensitivity than Beers' criteria in detecting prescription problems and have the added value of being able to detect not only inappropriate prescription of some drugs, but also the omission of well indicated drugs. The STOPP/START criteria could become a useful screening tool to improve prescription in older people. PMID:19540624

  3. System and method for transferring data on a data link

    NASA Technical Reports Server (NTRS)

    Cole, Robert M. (Inventor); Bishop, James E. (Inventor)

    2007-01-01

    A system and method are provided for transferring a packet across a data link. The packet may include a stream of data symbols which is delimited by one or more framing symbols. Corruptions of the framing symbol which result in valid data symbols may be mapped to invalid symbols. If it is desired to transfer one of the valid data symbols that has been mapped to an invalid symbol, the data symbol may be replaced with an unused symbol. At the receiving end, these unused symbols are replaced with the corresponding valid data symbols. The data stream of the packet may be encoded with forward error correction information to detect and correct errors in the data stream.

  4. Heat transfer enhancement in a paraffin wax thermal storage system

    SciTech Connect

    Eftekhar, J.; Haji-Sheikh, A.; Lou, Y.S.

    1984-08-01

    Heat transfer enhancement in a thermal storage system consisting of vertically arranged fins between a heated and cooled horizontal finned-tube arrangement is reported. The high thermal expansion coefficient and low viscosity of paraffin wax, at temperatures above 50/sup 0/C, are utilized to induce natural convection in the liquid phase even at small thicknesses. The experimental data on the rate of production of liquid as a function of time and temperature of the hot surface is presented. The photographs of the melted zone indicate a naturally buoyant flow induced in the neighborhood of the vertical fins causes a rapid melting of the solid wax and a downdraft along the cooler solid phase surface. The heat transfer coefficient at the interface is calculated from experimentally determined instantaneous locations of the moving boundary.

  5. Modeling coherent excitation energy transfer in photosynthetic light harvesting systems

    NASA Astrophysics Data System (ADS)

    Huo, Pengfei

    2011-12-01

    Recent non-linear spectroscopy experiments suggest the excitation energy transfer in some biological light harvesting systems initially occurs coherently. Treating such processes brings significant challenge for conventional theoretical tools that usually involve different approximations. In this dissertation, the recently developed Iterative Linearized Density Matrix (ILDM) propagation scheme, which is non-perturbative and non-Markovian is extended to study coherent excitation energy transfer in various light harvesting complexes. It is demonstrated that the ILDM approach can successfully describe the coherent beating of the site populations on model systems and gives quantitative agreement with both experimental results and the results of other theoretical methods have been developed recently to going beyond the usual approximations, thus providing a new reliable theoretical tool to study this phenomenon. This approach is used to investigate the excited energy transfer dynamics in various experimentally studied bacteria light harvesting complexes, such as Fenna-Matthews-Olsen (FMO) complex, Phycocyanin 645 (PC645). In these model calculations, quantitative agreement is found between computed de-coherence times and quantum beating pattens observed in the non-linear spectroscopy. As a result of these studies, it is concluded that the stochastic resonance behavior is important in determining the optimal throughput. To begin addressing possible mechanics for observed long de-coherence time, various models which include correlation between site energy fluctuations as well as correlation between site energy and inter-site coupling are developed. The influence of both types of correlation on the coherence and transfer rate is explored using with a two state system-bath hamiltonian parametrized to model the reaction center of Rhodobacter sphaeroides bacteria. To overcome the disadvantages of a fully reduced approach or a full propagation method, a brownian dynamics

  6. Affordable Launch Services using the Sport Orbit Transfer System

    NASA Astrophysics Data System (ADS)

    Goldstein, D. J.

    2002-01-01

    Despite many advances in small satellite technology, a low-cost, reliable method is needed to place spacecraft in their de- sired orbits. AeroAstro has developed the Small Payload ORbit Transfer (SPORTTM) system to provide a flexible low-cost orbit transfer capability, enabling small payloads to use low-cost secondary launch opportunities and still reach their desired final orbits. This capability allows small payloads to effectively use a wider variety of launch opportunities, including nu- merous under-utilized GTO slots. Its use, in conjunction with growing opportunities for secondary launches, enable in- creased access to space using proven technologies and highly reliable launch vehicles such as the Ariane family and the Starsem launcher. SPORT uses a suite of innovative technologies that are packaged in a simple, reliable, modular system. The command, control and data handling of SPORT is provided by the AeroAstro BitsyTM core electronics module. The Bitsy module also provides power regulation for the batteries and optional solar arrays. The primary orbital maneuvering capability is provided by a nitrous oxide monopropellant propulsion system. This system exploits the unique features of nitrous oxide, which in- clude self-pressurization, good performance, and safe handling, to provide a light-weight, low-cost and reliable propulsion capability. When transferring from a higher energy orbit to a lower energy orbit (i.e. GTO to LEO), SPORT uses aerobraking technol- ogy. After using the propulsion system to lower the orbit perigee, the aerobrake gradually slows SPORT via atmospheric drag. After the orbit apogee is reduced to the target level, an apogee burn raises the perigee and ends the aerobraking. At the conclusion of the orbit transfer maneuver, either the aerobrake or SPORT can be shed, as desired by the payload. SPORT uses a simple design for high reliability and a modular architecture for maximum mission flexibility. This paper will discuss the launch

  7. 12 CFR 611.1130 - Inter-System transfer of funds and equities.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Inter-System transfer of funds and equities... Rules for Inter-System Fund Transfers § 611.1130 Inter-System transfer of funds and equities. (a... funds and equities between institutions of the System, including banks, associations, and...

  8. 12 CFR 611.1130 - Inter-System transfer of funds and equities.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Inter-System transfer of funds and equities... Rules for Inter-System Fund Transfers § 611.1130 Inter-System transfer of funds and equities. (a... funds and equities between institutions of the System, including banks, associations, and...

  9. Heat transfer and flow in solar energy and bioenergy systems

    NASA Astrophysics Data System (ADS)

    Xu, Ben

    The demand for clean and environmentally benign energy resources has been a great concern in the last two decades. To alleviate the associated environmental problems, reduction of the use of fossil fuels by developing more cost-effective renewable energy technologies becomes more and more significant. Among various types of renewable energy sources, solar energy and bioenergy take a great proportion. This dissertation focuses on the heat transfer and flow in solar energy and bioenergy systems, specifically for Thermal Energy Storage (TES) systems in Concentrated Solar Power (CSP) plants and open-channel algal culture raceways for biofuel production. The first part of this dissertation is the discussion about mathematical modeling, numerical simulation and experimental investigation of solar TES system. First of all, in order to accurately and efficiently simulate the conjugate heat transfer between Heat Transfer Fluid (HTF) and filler material in four different solid-fluid TES configurations, formulas of an e?ective heat transfer coe?cient were theoretically developed and presented by extending the validity of Lumped Capacitance Method (LCM) to large Biot number, as well as verifications/validations to this simplified model. Secondly, to provide design guidelines for TES system in CSP plant using Phase Change Materials (PCM), a general storage tank volume sizing strategy and an energy storage startup strategy were proposed using the enthalpy-based 1D transient model. Then experimental investigations were conducted to explore a novel thermal storage material. The thermal storage performances were also compared between this novel storage material and concrete at a temperature range from 400 °C to 500 °C. It is recommended to apply this novel thermal storage material to replace concrete at high operating temperatures in sensible heat TES systems. The second part of this dissertation mainly focuses on the numerical and experimental study of an open-channel algae

  10. Energy transfer in mesoscopic vibrational systems enabled by eigenfrequency fluctuations

    NASA Astrophysics Data System (ADS)

    Atalaya, Juan

    Energy transfer between low-frequency vibrational modes can be achieved by means of nonlinear coupling if their eigenfrequencies fulfill certain nonlinear resonance conditions. Because of the discreteness of the vibrational spectrum at low frequencies, such conditions may be difficult to satisfy for most low-frequency modes in typical mesoscopic vibrational systems. Fluctuations of the vibrational eigenfrequencies can also be relatively strong in such systems. We show that energy transfer between modes can occur in the absence of nonlinear resonance if frequency fluctuations are allowed. The case of three modes with cubic nonlinear coupling and no damping is particularly interesting. It is found that the system has a non-thermal equilibrium state which depends only on the initial conditions. The rate at which the system approaches to such state is determined by the parameters such as the noise strength and correlation time, the nonlinearity strength and the detuning from exact nonlinear resonance. We also discuss the case of many weakly coupled modes. Our results shed light on the problem of energy relaxation of low-frequency vibrational modes into the continuum of high-frequency vibrational modes. The results have been obtained with Mark Dykman. Alternative email: jatalaya2012@gmail.com.

  11. The electron transfer system of synthrophically grown desulfovibrio vulgaris

    SciTech Connect

    Walker, Christopher; He, Zhili; Yang, Zamin Koo; Ringbauer, Joseph; HE, Qiang; Zhou, Jizhong; Voordouw, Gerrit; Wall, Judy; Arkin, Adam; Hazen, Terry; Stolyar, Sergey; Stahl, David

    2009-01-01

    Interspecies hydrogen transfer between organisms producing and consuming hydrogen promotes the decomposition of organic matter in most anoxic environments. Although syntrophic coupling between hydrogen producers and consumers is a major feature of the carbon cycle, mechanisms for energy recovery at the extremely low free energies of reactions typical of these anaerobic communities have not been established. In this study, comparative transcriptional analysis of a model sulfate-reducing microbe, Desulfovibrio vulgaris Hildenborough, suggested the use of alternative electron transfer systems dependent on growth modality. During syntrophic growth on lactate with a hydrogenotrophic methanogen, numerous genes involved in electron transfer and energy generation were upregulated in D. vulgaris compared with their expression in sulfate-limited monocultures. In particular, genes coding for the putative membrane-bound Coo hydrogenase, two periplasmic hydrogenases (Hyd and Hyn), and the well-characterized high-molecular-weight cytochrome (Hmc) were among the most highly expressed and upregulated genes. Additionally, a predicted operon containing genes involved in lactate transport and oxidation exhibited upregulation, further suggesting an alternative pathway for electrons derived from lactate oxidation during syntrophic growth. Mutations in a subset of genes coding for Coo, Hmc, Hyd, and Hyn impaired or severely limited syntrophic growth but had little effect on growth via sulfate respiration. These results demonstrate that syntrophic growth and sulfate respiration use largely independent energy generation pathways and imply that to understand microbial processes that sustain nutrient cycling, lifestyles not captured in pure culture must be considered.

  12. Homopolar machine for reversible energy storage and transfer systems

    DOEpatents

    Stillwagon, Roy E.

    1981-01-01

    A homopolar machine designed to operate as a generator and motor in reversibly storing and transferring energy between the machine and a magnetic load coil for a thermo-nuclear reactor. The machine rotor comprises hollow thin-walled cylinders or sleeves which form the basis of the system by utilizing substantially all of the rotor mass as a conductor thus making it possible to transfer substantially all the rotor kinetic energy electrically to the load coil in a highly economical and efficient manner. The rotor is divided into multiple separate cylinders or sleeves of modular design, connected in series and arranged to rotate in opposite directions but maintain the supply of current in a single direction to the machine terminals. A stator concentrically disposed around the sleeves consists of a hollow cylinder having a number of excitation coils each located radially outward from the ends of adjacent sleeves. Current collected at an end of each sleeve by sleeve slip rings and brushes is transferred through terminals to the magnetic load coil. Thereafter, electrical energy returned from the coil then flows through the machine which causes the sleeves to motor up to the desired speed in preparation for repetition of the cycle. To eliminate drag on the rotor between current pulses, the brush rigging is designed to lift brushes from all slip rings in the machine.

  13. Homopolar machine for reversible energy storage and transfer systems

    DOEpatents

    Stillwagon, Roy E.

    1978-01-01

    A homopolar machine designed to operate as a generator and motor in reversibly storing and transferring energy between the machine and a magnetic load coil for a thermo-nuclear reactor. The machine rotor comprises hollow thin-walled cylinders or sleeves which form the basis of the system by utilizing substantially all of the rotor mass as a conductor thus making it possible to transfer substantially all the rotor kinetic energy electrically to the load coil in a highly economical and efficient manner. The rotor is divided into multiple separate cylinders or sleeves of modular design, connected in series and arranged to rotate in opposite directions but maintain the supply of current in a single direction to the machine terminals. A stator concentrically disposed around the sleeves consists of a hollow cylinder having a number of excitation coils each located radially outward from the ends of adjacent sleeves. Current collected at an end of each sleeve by sleeve slip rings and brushes is transferred through terminals to the magnetic load coil. Thereafter, electrical energy returned from the coil then flows through the machine which causes the sleeves to motor up to the desired speed in preparation for repetition of the cycle. To eliminate drag on the rotor between current pulses, the brush rigging is designed to lift brushes from all slip rings in the machine.

  14. The Electron Transfer System of Syntrophically Grown Desulfovibrio vulgaris▿ †

    PubMed Central

    Walker, Christopher B.; He, Zhili; Yang, Zamin K.; Ringbauer, Joseph A.; He, Qiang; Zhou, Jizhong; Voordouw, Gerrit; Wall, Judy D.; Arkin, Adam P.; Hazen, Terry C.; Stolyar, Sergey; Stahl, David A.

    2009-01-01

    Interspecies hydrogen transfer between organisms producing and consuming hydrogen promotes the decomposition of organic matter in most anoxic environments. Although syntrophic coupling between hydrogen producers and consumers is a major feature of the carbon cycle, mechanisms for energy recovery at the extremely low free energies of reactions typical of these anaerobic communities have not been established. In this study, comparative transcriptional analysis of a model sulfate-reducing microbe, Desulfovibrio vulgaris Hildenborough, suggested the use of alternative electron transfer systems dependent on growth modality. During syntrophic growth on lactate with a hydrogenotrophic methanogen, numerous genes involved in electron transfer and energy generation were upregulated in D. vulgaris compared with their expression in sulfate-limited monocultures. In particular, genes coding for the putative membrane-bound Coo hydrogenase, two periplasmic hydrogenases (Hyd and Hyn), and the well-characterized high-molecular-weight cytochrome (Hmc) were among the most highly expressed and upregulated genes. Additionally, a predicted operon containing genes involved in lactate transport and oxidation exhibited upregulation, further suggesting an alternative pathway for electrons derived from lactate oxidation during syntrophic growth. Mutations in a subset of genes coding for Coo, Hmc, Hyd, and Hyn impaired or severely limited syntrophic growth but had little effect on growth via sulfate respiration. These results demonstrate that syntrophic growth and sulfate respiration use largely independent energy generation pathways and imply that to understand microbial processes that sustain nutrient cycling, lifestyles not captured in pure culture must be considered. PMID:19581361

  15. The Electron Transfer System of Syntrophically Grown Desulfovibrio vulgaris

    SciTech Connect

    PBD; ENIGMA; GTL; VIMSS; Walker, Christopher B.; He, Zhili; Yang, Zamin K.; Ringbauer Jr., Joseph A.; He, Qiang; Zhou, Jizhong; Voordouw, Gerrit; Wall, Judy D.; Arkin, Adam P.; Hazen, Terry C.; Stolyar, Sergey; Stahl, David A.

    2009-06-22

    Interspecies hydrogen transfer between organisms producing and consuming hydrogen promotes the decomposition of organic matter in most anoxic environments. Although syntrophic couplings between hydrogen producers and consumers are a major feature of the carbon cycle, mechanisms for energy recovery at the extremely low free energies of reactions typical of these anaerobic communities have not been established. In this study, comparative transcriptional analysis of a model sulfate-reducing microbe, Desulfovibrio vulgaris Hildenborough, suggested the use of alternative electron transfer systems dependent upon growth modality. During syntrophic growth on lactate with a hydrogenotrophic methanogen, D. vulgaris up-regulated numerous genes involved in electron transfer and energy generation when compared with sulfate-limited monocultures. In particular, genes coding for the putative membrane-bound Coo hydrogenase, two periplasmic hydrogenases (Hyd and Hyn) and the well-characterized high-molecular weight cytochrome (Hmc) were among the most highly expressed and up-regulated. Additionally, a predicted operon coding for genes involved in lactate transport and oxidation exhibited up-regulation, further suggesting an alternative pathway for electrons derived from lactate oxidation during syntrophic growth. Mutations in a subset of genes coding for Coo, Hmc, Hyd and Hyn impaired or severely limited syntrophic growth but had little affect on growth via sulfate-respiration. These results demonstrate that syntrophic growth and sulfate-respiration use largely independent energy generation pathways and imply that understanding of microbial processes sustaining nutrient cycling must consider lifestyles not captured in pure culture.

  16. The electron transfer system of syntrophically grown Desulfovibrio vulgaris

    SciTech Connect

    Walker, C.B.; He, Z.; Yang, Z.K.; Ringbauer, Jr., J.A.; He, Q.; Zhou, J.; Voordouw, G.; Wall, J.D.; Arkin, A.P.; Hazen, T.C.; Stolyar, S.; Stahl, D.A.

    2009-05-01

    Interspecies hydrogen transfer between organisms producing and consuming hydrogen promotes the decomposition of organic matter in most anoxic environments. Although syntrophic couplings between hydrogen producers and consumers are a major feature of the carbon cycle, mechanisms for energy recovery at the extremely low free energies of reactions typical of these anaerobic communities have not been established. In this study, comparative transcriptional analysis of a model sulfate-reducing microbe, Desulfovibrio vulgaris Hildenborough, suggested the use of alternative electron transfer systems dependent upon growth modality. During syntrophic growth on lactate with a hydrogenotrophic methanogen, D. vulgaris up-regulated numerous genes involved in electron transfer and energy generation when compared with sulfate-limited monocultures. In particular, genes coding for the putative membrane-bound Coo hydrogenase, two periplasmic hydrogenases (Hyd and Hyn) and the well-characterized high-molecular weight cytochrome (Hmc) were among the most highly expressed and up-regulated. Additionally, a predicted operon coding for genes involved in lactate transport and oxidation exhibited up-regulation, further suggesting an alternative pathway for electrons derived from lactate oxidation during syntrophic growth. Mutations in a subset of genes coding for Coo, Hmc, Hyd and Hyn impaired or severely limited syntrophic growth but had little affect on growth via sulfate-respiration. These results demonstrate that syntrophic growth and sulfate-respiration use largely independent energy generation pathways and imply that understanding of microbial processes sustaining nutrient cycling must consider lifestyles not captured in pure culture.

  17. Derivation of various transfer functions of ideal or aberrated imaging systems from the three-dimensional transfer function.

    PubMed

    Braat, Joseph J M; Janssen, Augustus J E M

    2015-06-01

    The three-dimensional frequency transfer function for optical imaging systems was introduced by Frieden in the 1960s. The analysis of this function and its partly back-transformed functions (two-dimensional and one-dimensional optical transfer functions) in the case of an ideal or aberrated imaging system has received relatively little attention in the literature. Regarding ideal imaging systems with an incoherently illuminated object volume, we present analytic expressions for the classical two-dimensional x-y-transfer function in a defocused plane, for the axial z-transfer function in the presence of defocusing and for the x-z-transfer function in the presence of a lateral shift δy with respect to the imaged pattern in the x-z-plane. For an aberrated imaging system we use the common expansion of the aberrated pupil function with the aid of Zernike polynomials. It is shown that the line integral appearing in Frieden's three-dimensional transfer function can be evaluated for aberrated systems using a relationship established first by Cormack between the line integral of a Zernike polynomial over a full chord of the unit disk and a Chebyshev polynomial of the second kind. Some new developments in the theory of Zernike polynomials from the last decade allow us to present explicit expressions for the line integral in the case of a weakly aberrated imaging system. We outline a similar, but more complicated, analytic scheme for the case of severely aberrated systems.

  18. Container lid gasket protective strip for double door transfer system

    DOEpatents

    Allen, Jr., Burgess M

    2013-02-19

    An apparatus and a process for forming a protective barrier seal along a "ring of concern" of a transfer container used with double door systems is provided. A protective substrate is supplied between a "ring of concern" and a safety cover in which an adhesive layer of the substrate engages the "ring of concern". A compressive foam strip along an opposite side of the substrate engages a safety cover such that a compressive force is maintained between the "ring of concern" and the adhesive layer of the substrate.

  19. Material transfer system in support of the plutonium immobilization program

    SciTech Connect

    Pak, D

    2000-02-23

    The Plutonium Immobilization Project is currently undertaking formulation and process development to demonstrate the immobilization of surplus plutonium in a titanate-based ceramic. These ceramic forms will be encapsulated within canisters containing high level waste glass for geologic disposal. Process development work is being conducted with sub-scale, process prototypic equipment. Final validation of the process will be done using actual plutonium material and functionally prototypic equipment within a glovebox. Due to the radioactive nature of the material, remote material handling is necessary to reduce the radiation exposure to the operators. A remote operated Material Transfer System to interface with process equipment has been developed.

  20. Experimental Study of RF Energy Transfer System in Indoor Environment

    NASA Astrophysics Data System (ADS)

    Adami, S.-E.; Proynov, P. P.; Stark, B. H.; Hilton, G. S.; Craddock, I. J.

    2014-11-01

    This paper presents a multi-transmitter, 2.43 GHz Radio-Frequency (RF) wireless power transfer (WPT) system for powering on-body devices. It is shown that under typical indoor conditions, the received power range spans several orders of magnitude from microwatts to milliwatts. A body-worn dual-polarised rectenna (rectifying antenna) is presented, designed for situations where the dominant polarization is unpredictable, as is the case for the on-body sensors. Power management circuitry is demonstrated that optimally loads the rectenna even under highly intermittent conditions, and boosts the voltage to charge an on-board storage capacitor.

  1. User Interface Technology Transfer to NASA's Virtual Wind Tunnel System

    NASA Technical Reports Server (NTRS)

    vanDam, Andries

    1998-01-01

    Funded by NASA grants for four years, the Brown Computer Graphics Group has developed novel 3D user interfaces for desktop and immersive scientific visualization applications. This past grant period supported the design and development of a software library, the 3D Widget Library, which supports the construction and run-time management of 3D widgets. The 3D Widget Library is a mechanism for transferring user interface technology from the Brown Graphics Group to the Virtual Wind Tunnel system at NASA Ames as well as the public domain.

  2. Energy Transfer in the Earth-Sun System

    NASA Astrophysics Data System (ADS)

    Lui, A. T. Y.; Kamide, Y.

    2007-02-01

    Conference on Earth-Sun System Exploration: Energy Transfer; Kailua-Kona, Hawaii, USA, 16-20 January 2006; The goal of this conference, which was supported by several agencies and organizations, was to provide a forum for physicists engaged in the Earth-Sun system as well as in laboratory experiments to discuss and exchange knowledge and ideas on physical processes involving energy transfer. The motivation of the conference stemmed from the following realization: Space assets form an important fabric of our society, performing functions such as television broadcasting, cell- phone communication, navigation, and remote monitoring of tropospheric weather. There is increasing awareness of how much our daily activities can be adversely affected by space disturbances stretching all the way back to the Sun. In some of these energetic phenomena, energy in various forms can propagate long distances from the solar surface to the interplanetary medium and eventually to the Earth's immediate space environment, namely, its magnetosphere, ionosphere, and thermosphere. In addition, transformation of energy can take place in these space disturbances, allowing charged-particle energy to be transformed to electromagnetic energy or vice versa. In- depth understanding of energy transformation and transmission in the Earth-Sun system will foster the identification of physical processes responsible for space disturbances and the prediction of their occurrences and effects. Participants came from 15 countries.

  3. Thermodynamic aspects of information transfer in complex dynamical systems.

    PubMed

    Cafaro, Carlo; Ali, Sean Alan; Giffin, Adom

    2016-02-01

    From the Horowitz-Esposito stochastic thermodynamical description of information flows in dynamical systems [J. M. Horowitz and M. Esposito, Phys. Rev. X 4, 031015 (2014)], it is known that while the second law of thermodynamics is satisfied by a joint system, the entropic balance for the subsystems is adjusted by a term related to the mutual information exchange rate between the two subsystems. In this article, we present a quantitative discussion of the conceptual link between the Horowitz-Esposito analysis and the Liang-Kleeman work on information transfer between dynamical system components [X. S. Liang and R. Kleeman, Phys. Rev. Lett. 95, 244101 (2005)]. In particular, the entropic balance arguments employed in the two approaches are compared. Notwithstanding all differences between the two formalisms, our work strengthens the Liang-Kleeman heuristic balance reasoning by showing its formal analogy with the recent Horowitz-Esposito thermodynamic balance arguments. PMID:26986295

  4. Recalibrating the BC Transfer System: Findings from the Consultation. Special Report, June 2007

    ERIC Educational Resources Information Center

    British Columbia Council on Admissions and Transfer, 2007

    2007-01-01

    In November 2005, the BC Council on Admissions and Transfer launched a consultation, Recalibrating the BC Transfer System, motivated by significant changes in the BC post-secondary system over the last decade and concern that these changes had not resulted in concomitant adjustments in the structure of the BC Transfer System or the BC Transfer…

  5. The “Black Box” of Prescription Drug Diversion

    PubMed Central

    Inciardi, James A.; Surratt, Hilary L.; Cicero, Theodore J.; Kurtz, Steven P.; Martin, Steven S.; Parrino, Mark W.

    2009-01-01

    A variety of surveys and studies are examined in an effort to better understand the scope of prescription drug diversion and to determine if there are consistent patterns of diversion among various populations of prescription drug abusers. Data are drawn from the RADARS® System, the National Survey of Drug Use and Health (NSDUH), the Delaware School Survey, and a series of quantitative and qualitative studies conducted in Miami, Florida. The data suggest that the major sources of diversion include drug dealers, friends and relatives, smugglers, pain patients, and the elderly, but these vary by the population being targeted. In all of the studies examined, the use of the Internet as a source for prescription drugs is insignificant. Little is known about where drug dealers are obtaining their supplies, and as such, prescription drug diversion is a “black box” requiring concentrated systematic study. PMID:20155603

  6. A technology transfer tracking system for NREL: Overview and results

    SciTech Connect

    Chapman, R.L.; Chapman, M.J.

    1996-07-01

    The purpose of this study has been to assess the National Renewable Energy Laboratory`s (NREL) technology, transfer--both the activities and the system, with the objective of developing a system to track the benefits of NREL-sponsored or conducted research. There were two factors which facilitated this study and which were important in the ability to make a detailed analysis and series of recommendations. First, was the nature of the lab, being one which, from its beginning, has worked closely with industry and, therefore has been directed toward research which would be of value to industry and hopefully commercialized. Second, the size of the laboratory made it relatively more easy to address issues and to become familiar with the organization and with the scientists themselves.

  7. Heat transfer analysis for peripheral blood flow measurement system

    NASA Astrophysics Data System (ADS)

    Nagata, Koji; Hattori, Hideharu; Sato, Nobuhiko; Ichige, Yukiko; Kiguchi, Masashi

    2009-06-01

    Some disorders such as circulatory disease and metabolic abnormality cause many problems to peripheral blood flow condition. Therefore, frequent measurement of the blood flow condition is bound to contribute to precaution against those disorders and to control of conditions of the diseases. We propose a convenient means of blood flow volume measurement at peripheral part, such as fingertips. Principle of this measurement is based on heat transfer characteristics of peripheral part containing the blood flow. Transition response analysis of skin surface temperature has provided measurement model of the peripheral blood flow volume. We developed the blood flow measurement system based on that model and evaluated it by using artificial finger under various temperature conditions of ambience and internal fluid. The evaluation results indicated that proposed method could estimate the volume of the fluid regardless of temperature condition of them. Finally we applied our system to real finger testing and have obtained results correlated well with laser Doppler blood flow meter values.

  8. A comparison of potential electric propulsion systems for orbit transfer

    NASA Technical Reports Server (NTRS)

    Jones, R. M.

    1982-01-01

    Electric propulsion concepts are compared on the basis of trip time for the low earth orbit (LEO) to geosynchronous earth orbit (GEO) mission. Resistojet, arcjet, magnetoplasmadynamic (MPD), pulsed inductive, and ion engine thruster concepts are included. The optimum (minimum trip time) value of specific impulse is found to be dependent upon the specific mission and system being considered. As expected, the devices which can deliver good efficiency at low specific impulses promise the fastest trip times. The solution for trip time and propellant mass for the constant power, continuous low acceleration orbit transfer problem (one way and round trip) is presented in nomograph form. The influences of mission Delta V, thruster efficiency, specific impulse, power, power and propulsion system mass, and payload mass are clearly illustrated.

  9. Transfer printing and micro-scale hybrid materials systems

    NASA Astrophysics Data System (ADS)

    Meitl, Matthew Alexander

    Micro- and nano-scale engineering, especially as it applies to integrated circuits, has impacted society in revolutionary ways. These integrated circuits are characterized by huge numbers of small electronic devices manufactured on semiconductor wafers. Some emerging technologies will require assemblies of these micro/nano-devices on substrates that are very different from semiconductor wafers in terms of processing schemes and properties. Integration of high quality semiconductors and devices onto large, low-cost, mechanically- deformable, polymeric (plastic or elastomer), and/or functional substrates for unconventional electronics applications (displays, systems-on-a-chip) are a few examples. This dissertation presents methods for assembling small-scale (˜nm to ˜mm) materials elements and devices on many classes of substrate (planar or simply-curved with nearly arbitrary composition) via transfer printing, a form of soft lithography. The approach uses rubber stamps to manipulate arrays of small-scale objects including but not limited to carbon nanotubes, metal thin films, single-crystal silicon and III-V semiconductor microstructures and devices, few-layer graphene, and silica microspheres. Presented here are the techniques for preparing printable materials elements and devices from solution (e.g. surfactant stabilized aqueous carbon nanotube solutions) and from donor/source substrates (e.g. semiconductor wafers) as well as the mechanical phenomena that govern the transfer of materials to and from the stamp. Among these are kinetically-switchable adhesion to a viscoelastic stamp and stress focusing via sharp geometries for controlling fracture. Also presented here are thin-film transistors, photodiodes, and inorganic light-emitting diodes on plastic substrates as well as semiconductor woodpile structures and silicon-III-V heterogeneous integration, examples of the capabilities of the transfer printing approach.

  10. Stress Transfer and Structural Failure of Bilayered Material Systems

    NASA Astrophysics Data System (ADS)

    Prieto-Munoz, Pablo Arthur

    Bilayered material systems are common in naturally formed or artificially engineered structures. Understanding how loads transfer within these structural systems is necessary to predict failure and develop effective designs. Existing methods for evaluating the stress transfer in bilayered materials are limited to overly simplified models or require experimental calibration. As a result, these methods have failed to accurately account for such structural failures as the creep induced roofing panel collapse of Boston's I-90 connector tunnel, which was supported by adhesive anchors. The one-dimensional stress analyses currently used for adhesive anchor design cannot account for viscoelastic creep failure, and consequently results in dangerously under-designed structural systems. In this dissertation, a method for determining the two-dimensional stress and displacement fields for a generalized bilayered material system is developed, and proposes a closed-form analytical solution. A general linear-elastic solution is first proposed by decoupling the elastic governing equations from one another through the so-called plane assumption. Based on this general solution, an axisymmetric problem and a plane strain problem are formulated. These are applied to common bilayered material systems such as: (1) concrete adhesive anchors, (2) material coatings, (3) asphalt pavements, and (4) layered sedimentary rocks. The stress and displacement fields determined by this analytical analysis are validated through the use of finite element models. Through the correspondence principle, the linear-elastic solution is extended to consider time-dependent viscoelastic material properties, thus facilitating the analysis of adhesive anchors and asphalt pavements while incorporating their viscoelastic material behavior. Furthermore, the elastic stress analysis can explain the fracturing phenomenon of material coatings, pavements, and layered rocks, successfully predicting their fracture

  11. Apparatus and Method for Effecting Data Transfer Between Data Systems

    NASA Technical Reports Server (NTRS)

    Kirkpatrick, Joey V. (Inventor); Grosz, Francis B., Jr. (Inventor); Lannes, Kenny (Inventor); Maniscalco, David G. (Inventor)

    2001-01-01

    An apparatus for effecting data transfer between data systems comprising a first transceiver and a second transceiver. The first transceiver has an input for receiving digital data from one of the data systems, an output for serially outputting digital data to one of the data systems, at least one transmitter for converting digital data received at the input into optical signals, and at least one receiver for receiving optical signals and serially converting the received optical signals to digital data for output to the data output. The second transceiver has an input for receiving digital data from another one of the data systems, an output for serially outputting digital data to the another one of the data systems, at least one transmitter for serially converting digital data received at the input of the second transceiver into optical signals, and at least one receiver for receiving optical signals and serially converting the received optical signals to digital data for output to the output of the second transceiver. The apparatus further comprises an optical link connecting the first and second transceivers. The optical link comprising a pair of optical fibers. One of the optical fibers optically links the transmitter of the first transceiver to the receiver of the second transceiver. The other optical fiber optically links the receiver of the first transceiver to the transmitter of the second transceiver.

  12. Association Between Prescription Drug Benefit and Hospital Readmission Rates

    PubMed Central

    Kelso, Christine; Gandhi, Bhumi

    2014-01-01

    Purpose: To determine whether primary care medicine clinic (PCMC) patients with a prescription drug benefit were associated with a lower rate of hospital readmissions. Methods: This study was a retrospective, single-center, cohort study of PCMC patients who had at least 1 hospital readmission in 2011. Eligible patients were divided into 2 groups: patients without prescription drug benefits and patients with prescription drug benefits. Results: Three hundred fifty-two patients met our inclusion criteria. The number of hospital readmissions for patients with a prescription drug benefit was higher than those with no prescription drug benefit (2.453 ± 2.49 vs 1.88 ± 1.91; P = .052). The length of index admission and the length of hospital readmission in days were higher in patients with no prescription drug benefits (index admission, 5.29 ± 6.38 vs 4.59 ± 4.50; P = .428) (readmission, 5.31 ± 5.90 vs 4.48 ± 4.33, P = .166). The number of days to readmission was higher in those with drug benefits (58.12 ± 63.54 vs 53.39 ± 53.47; P = .316). When patient data were separated by CCI scores, it was noted that patients with pharmacy benefits had significantly more hospital readmissions in each CCI score category except for patients with a CCI of 6. Conclusion: Although not statistically significant, patients with prescription drug benefits had more hospital readmissions but shorter hospital lengths of stay. Significant data linking hospital readmissions and prescription insurance benefits, if found in future studies, would provide helpful guidance to health care systems. PMID:24958957

  13. POPI (Pediatrics: Omission of Prescriptions and Inappropriate Prescriptions): Development of a Tool to Identify Inappropriate Prescribing

    PubMed Central

    Prot-Labarthe, Sonia; Weil, Thomas; Angoulvant, François; Boulkedid, Rym; Alberti, Corinne; Bourdon, Olivier

    2014-01-01

    Introduction Rational prescribing for children is an issue for all countries and has been inadequately studied. Inappropriate prescriptions, including drug omissions, are one of the main causes of medication errors in this population. Our aim is to develop a screening tool to identify omissions and inappropriate prescriptions in pediatrics based on French and international guidelines. Methods A selection of diseases was included in the tool using data from social security and hospital statistics. A literature review was done to obtain criteria which could be included in the tool called POPI. A 2-round-Delphi consensus technique was used to establish the content validity of POPI; panelists were asked to rate their level of agreement with each proposition on a 9-point Likert scale and add suggestions if necessary. Results 108 explicit criteria (80 inappropriate prescriptions and 28 omissions) were obtained and submitted to a 16-member expert panel (8 pharmacists, 8 pediatricians hospital-based −50%- or working in community −50%-). Criteria were categorized according to the main physiological systems (gastroenterology, respiratory infections, pain, neurology, dermatology and miscellaneous). Each criterion was accompanied by a concise explanation as to why the practice is potentially inappropriate in pediatrics (including references). Two round of Delphi process were completed via an online questionnaire. 104 out of the 108 criteria submitted to experts were selected after 2 Delphi rounds (79 inappropriate prescriptions and 25 omissions). Discussion Conclusion POPI is the first screening-tool develop to detect inappropriate prescriptions and omissions in pediatrics based on explicit criteria. Inter-user reliability study is necessary before using the tool, and prospective study to assess the effectiveness of POPI is also necessary. PMID:24978045

  14. The burden of the nonmedical use of prescription opioid analgesics.

    PubMed

    Gilson, Aaron M; Kreis, Paul G

    2009-07-01

    An increase in the prescribing of opioids over the past several years often has been perceived as the primary reason for the increase in the nonmedical use of prescription opioids. Determining the prevalence of this illicit use has been difficult, because of varied methodologies and terminologies that are used to estimate the number of people directly contributing to or affected by this burden. Despite these discrepancies, the findings from several nationally recognized surveys have demonstrated that the prevalence of nonmedical prescription opioid use is indeed significant and has been increasing in recent years. The considerable burden on society imposed by misuse and abuse of these drugs is largely due to the monetary costs associated with nonmedical use (e.g., strategies implemented to prevent or deter abuse, treatment programs for misusers, etc.), decreased economic productivity, and the indirect effect on access to appropriate health care. However, using various nonpharmacologic and pharmacologic approaches to treat patients who use prescription opioids illicitly can decrease its overall prevalence and associated impact, with the development of novel opioid formulations designed to reduce nonmedical use providing valuable clinical tools as part of an overall risk management program. In addition, prescription monitoring programs are a prevalent drug control system designed to identify and address abuse and diversion of prescription medications, including opioids. Such resources, along with an accurate understanding of the problem, extend greater hope that the public health challenge of nonmedical prescription opioid use can be effectively mitigated. PMID:19691688

  15. Heat transfer in minichannels and microchannels CPU cooling systems

    NASA Astrophysics Data System (ADS)

    Mihai, Ioan C.

    2009-01-01

    A CPU functioning is extremely complex and it was experimentally revealed that a direct dependence between working speed and cooling degree exists. When the contact between two surfaces is imperfect, the specific thermal resistance of interface layer suddenly increases, so it became of frequent use to apply diverse materials between the CPU and radiator. These materials should both fill the gaps occurred due to surfaces roughness, material's fatigue, loading pressure etc. and transfer as much heat as possible during a short period of time. In order to ensure an appropriate cooling, other complementary methods are used, such as coolers, water or other liquids cooling, Peltier effect and even freon micro-refrigerating systems. In either situation, there are micro or nano channels through which fluids flow and thermal exchange takes place. The present paper aims to analyze the heat transfer under the mentioned conditions, considering the micro or nano scale dimensions of the channels. The thermal calculus can differ with respect to Kn number and for this case for thermal modelling diverse mathematical models can be realized. The model used is validated by comparing the results to numerical results obtained by authors from literature.

  16. Heat transfer in vacuum packaged microelectromechanical system devices

    NASA Astrophysics Data System (ADS)

    Cai, Chunpei

    2008-01-01

    This study analyzes heat transfer effects inside vacuum packaged microelectromechanical system (MEMS) devices. A packaged device is simplified as four plates forming a square cavity, the bottom plate represents a hot chip, while the other three plates are maintained at room temperature. For a highly rarefied free molecular internal gas flow scenario, the corresponding detailed density and temperature fields are analytically determined with a proposed speculation. This speculation indicates that for a steady free molecular gas flow inside a convex closure domain formed by walls maintained at different temperatures: (1) the velocity distribution functions for those molecules diffusely reflected at different walls and traveling away from them are Maxwellian with different number densities; (2) for each distribution, ni√Ti is a constant, where ni is the number density for the group of reflected molecules, and Ti is the temperature for the ith plate. For a near continuum flow scenario, the governing energy equation degenerates to Laplace's equation with several temperature-jump wall boundary conditions. This study also includes discussions and comparisons among analytical results, simulation results from the direct simulation Monte Carlo method, and results by solving the Navier-Stokes equations with proper wall boundary conditions. The approach used in this study is generally applicable to study internal flows and heat transfer effects in other vacuum packaged MEMS devices with different shapes.

  17. Situational and Demographic Influences on Transfer System Characteristics in Organizations

    ERIC Educational Resources Information Center

    Chen, Hsin-Chih; Holton, Elwood F., III; Bates, Reid A.

    2006-01-01

    Transfer theories, which are closely related to evaluation theory, have been developed from a holistic perspective, but most of empirical transfer research has not effectively utilized holistic models to investigate transfer of learning until the late 1990s. Additionally, little has been done in examining the relationship between situational…

  18. Crowdsourcing Black Market Prices For Prescription Opioids

    PubMed Central

    Freifeld, Clark; Brownstein, John S; Menone, Christopher Mark; Surratt, Hilary L; Poppish, Luke; Green, Jody L; Lavonas, Eric J; Dart, Richard C

    2013-01-01

    Background Prescription opioid diversion and abuse are major public health issues in the United States and internationally. Street prices of diverted prescription opioids can provide an indicator of drug availability, demand, and abuse potential, but these data can be difficult to collect. Crowdsourcing is a rapid and cost-effective way to gather information about sales transactions. We sought to determine whether crowdsourcing can provide accurate measurements of the street price of diverted prescription opioid medications. Objective To assess the possibility of crowdsourcing black market drug price data by cross-validation with law enforcement officer reports. Methods Using a crowdsourcing research website (StreetRx), we solicited data about the price that site visitors paid for diverted prescription opioid analgesics during the first half of 2012. These results were compared with a survey of law enforcement officers in the Researched Abuse, Diversion, and Addiction-Related Surveillance (RADARS) System, and actual transaction prices on a “dark Internet” marketplace (Silk Road). Geometric means and 95% confidence intervals were calculated for comparing prices per milligram of drug in US dollars. In a secondary analysis, we compared prices per milligram of morphine equivalent using standard equianalgesic dosing conversions. Results A total of 954 price reports were obtained from crowdsourcing, 737 from law enforcement, and 147 from the online marketplace. Correlations between the 3 data sources were highly linear, with Spearman rho of 0.93 (P<.001) between crowdsourced and law enforcement, and 0.98 (P<.001) between crowdsourced and online marketplace. On StreetRx, the mean prices per milligram were US$3.29 hydromorphone, US$2.13 buprenorphine, US$1.57 oxymorphone, US$0.97 oxycodone, US$0.96 methadone, US$0.81 hydrocodone, US$0.52 morphine, and US$0.05 tramadol. The only significant difference between data sources was morphine, with a Drug Diversion price of US

  19. System design concepts and requirements for aeroassisted orbital transfer vehicles

    NASA Technical Reports Server (NTRS)

    Austin, R. E.; Cruz, M. I.; French, J. R.

    1982-01-01

    The Orbital Transfer Vehicle (OTV) is an advanced upper stage concept which will deliver spacecraft from operating systems at Low Earth Orbit (LEO) such as Space Shuttle, Earth-To-Orbit (ETO) vehicles, and Space Operations Center (SOC), to High Earth Orbit (HEO) and planetary excursions. The OTV will be driven by the need to achieve significant reductions in the operational costs for delivering payloads to Geostationary Equatorial Orbit (GEO). Aeroassist is a technological capability that has a potential for OTV's ranging from mission enhancing (reusable OTV for payload delivery) to mission enabling (manned GEO and some DOD). It is shown that the use of aeroassist for OTV's is a high leverage technology which can potentially reduce space transportation costs and enable a number of highly desirable missions.

  20. The Magsat three axis arc second precision attitude transfer system

    NASA Technical Reports Server (NTRS)

    Schenkel, F. W.; Heins, R. J.

    1981-01-01

    The Magsat Attitude Transfer System (ATS), which provides attitude alteration in pitch, yaw, and roll is described. A remote vector magnetometer extends from Magsat on a 20 ft boom, requiring vector orientation by reference to coordinate axes determined by a set of star mapping cameras. The ATS was designed to perform in a solar illuminated environment by using an optically narrow bandwidth with synchronous demodulation at 9300 A. The pitch/yaw optical design, the electrooptics, and signal and switching diagrams are provided. Simple mirrors with no moving parts are placed on the magnetometer to reflect a collimated beam from the ATS for attitude indication, which is accurate to one part in 96. Alignment was completed within 24 hr after launch.

  1. Orbital Transfer Vehicle: Concept definition and system analysis study

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Findings and recommendations from the second extension of the Orbital Transfer Vehicle (OTV) concept definition and system analysis study are outlined. The extension study opens the scope of potential recommendations by introducing a variety of ambitious programs, and by making the large cargo vehicle recommended by the Space Transportation Architecture Studies available at no acquisition cost to the OTV program. It is a further objective of the extension study to evaluate the sensitivity of OTV program recommendations to scenario variations such as different mission models, different launch vehicle availability, and different space station availability. Program/mission issues are addressed including safety considerations for the Aft Cargo Carrier (ACC) OTV. Design issues related to the development of a near-term expendable OTV, engine configuration tradeoffs, lunar missions, and program evolution are discussed. Finally, aeroassist considerations for a manned Mars mission and high speed entries are presented.

  2. Extracellular electron transfer systems fuel cellulose oxidative degradation.

    PubMed

    Kracher, Daniel; Scheiblbrandner, Stefan; Felice, Alfons K G; Breslmayr, Erik; Preims, Marita; Ludwicka, Karolina; Haltrich, Dietmar; Eijsink, Vincent G H; Ludwig, Roland

    2016-05-27

    Ninety percent of lignocellulose-degrading fungi contain genes encoding lytic polysaccharide monooxygenases (LPMOs). These enzymes catalyze the initial oxidative cleavage of recalcitrant polysaccharides after activation by an electron donor. Understanding the source of electrons is fundamental to fungal physiology and will also help with the exploitation of LPMOs for biomass processing. Using genome data and biochemical methods, we characterized and compared different extracellular electron sources for LPMOs: cellobiose dehydrogenase, phenols procured from plant biomass or produced by fungi, and glucose-methanol-choline oxidoreductases that regenerate LPMO-reducing diphenols. Our data demonstrate that all three of these electron transfer systems are functional and that their relative importance during cellulose degradation depends on fungal lifestyle. The availability of extracellular electron donors is required to activate fungal oxidative attack on polysaccharides.

  3. Quantum Process Tomography for Energy Transfer Systems via Ultrafast Spectroscopy

    NASA Astrophysics Data System (ADS)

    Yuen-Zhou, Joel

    2012-02-01

    The description of excited state dynamics in energy transfer systems constitutes a theoretical and experimental challenge in modern chemical physics. A spectroscopic protocol that systematically characterizes both coherent and dissipative processes of the probed chromophores is desired [1,2]. In this talk, I show that a set of two-color photon-echo experiments performs quantum state tomography (QST) of the one-exciton manifold of a dimer by reconstructing its density matrix in real time. This possibility in turn allows for a complete description of excited state dynamics via quantum process tomography (QPT). Simulations of a noisy QPT experiment for an inhomogeneously broadened ensemble of model excitonic dimers show that the protocol distills rich information about dissipative excitonic dynamics, which appears nontrivially hidden in the signal monitored in single realizations of four-wave mixing experiments Progress on the experimental side will be discussed, as well as new insights that QPT has offered on the understanding of 2D electronic and vibrational spectroscopy. [1] J. Yuen-Zhou, J. J. Krich, A. Aspuru-Guzik, Quantum state and process tomography of energy transfer systems via ultrafast spectroscopy Joel Yuen-Zhou, Jacob J. Krich, Masoud Mohseni and Al'an Aspuru-Guzik Proc. Nat. Acad. Sci. USA, Early Edition (2011). [2] J. Yuen-Zhou, A. Aspuru-Guzik, Quantum process tomography of molecular dimers from two-dimensional electronic spectroscopy I: General theory and application to homodimers Joel Yuen-Zhou and Al'an Aspuru-Guzik . Chem. Phys. 134, 134505 (2011).

  4. Prescription Program Provides Significant Savings

    ERIC Educational Resources Information Center

    Rowan, James M.

    2010-01-01

    Most school districts today are looking for ways to save money without decreasing services to its staff. Retired pharmacist Tim Sylvester, a lifelong resident of Alpena Public Schools in Alpena, Michigan, presented the district with a pharmaceuticals plan that would save the district money without raising employee co-pays for prescriptions. The…

  5. Prescriptive Teaching Workshop Resource Manual.

    ERIC Educational Resources Information Center

    Bennett, Mildred E.; And Others

    The resource manual describes procedures for replication of a 1 year Prescriptive Teaching Workshop project, a Title III educational program designed to maintain the learning disabled elementary school child in the regular classroom with additional special workshop help in order to raise his academic achievement. Evaluation of the student is by a…

  6. Learning Disabilities: Diagnosis and Prescription.

    ERIC Educational Resources Information Center

    Kappelman, Murray M.

    The author advocates an interdisciplinary team approach to diagnosis and prescription for the elementary school learning disabled (LD) child. Described is a 5-year project, funded under Title VI, operating within 11-18 elementary schools surrounding the University of Maryland Hospital. Biweekly services are offered to participating schools by a…

  7. Exercise Prescription for Physical Fitness.

    ERIC Educational Resources Information Center

    Pollock, Michael L.; And Others

    1995-01-01

    Examines current guidelines for physical fitness, noting issues that may influence the updating of the American College of Sports Medicine exercise statement. Differences between exercise prescription for fitness and physical activity for health are discussed, noting the importance of designing individualized programs with appropriate levels of…

  8. Prescriptive Exercise for Older Adults.

    ERIC Educational Resources Information Center

    Piscopo, John

    1985-01-01

    In addition to physical benefits, exercise also provides a natural way to sustain mental alertness in the aging individual by supplying oxygen to the brain. A table focuses on 10 specific health-fitness problems with suggested prescriptive exercises designed to ameliorate the condition. (MT)

  9. Shoe Inserts and Prescription Custom Orthotics

    MedlinePlus

    ... Feet » Foot Health Information Shoe Inserts and Prescription Custom Orthotics What are Shoe Inserts? You've seen ... hold on to your receipt.) What are Prescription Custom Orthotics? Custom orthotics are specially-made devices designed ...

  10. What Are Some Commonly Abused Prescription Drugs?

    MedlinePlus

    ... Trends and Alerts Alcohol Club Drugs Cocaine Hallucinogens Heroin Inhalants Marijuana MDMA (Ecstasy/Molly) Methamphetamine Opioids Prescription ... View all ​Research Reports Opioids: The Prescription Drug & Heroin Overdose Epidemic (HHS website) NIDA Home Site Map ...

  11. Opioids: The Prescription Drug & Heroin Overdose Epidemic

    MedlinePlus

    ... Resources Law Enforcement Resources Opioids: The Prescription Drug & Heroin Overdose Epidemic Opioids are natural or synthetic chemicals ... in your brain or body. Common opioids include heroin and prescription drugs such as oxycodone, hydrocodone, and ...

  12. Secure Data Transfer Guidance for Industrial Control and SCADA Systems

    SciTech Connect

    Mahan, Robert E.; Fluckiger, Jerry D.; Clements, Samuel L.; Tews, Cody W.; Burnette, John R.; Goranson, Craig A.; Kirkham, Harold

    2011-09-01

    This document was developed to provide guidance for the implementation of secure data transfer in a complex computational infrastructure representative of the electric power and oil and natural gas enterprises and the control systems they implement. For the past 20 years the cyber security community has focused on preventative measures intended to keep systems secure by providing a hard outer shell that is difficult to penetrate. Over time, the hard exterior, soft interior focus changed to focus on defense-in-depth adding multiple layers of protection, introducing intrusion detection systems, more effective incident response and cleanup, and many other security measures. Despite much larger expenditures and more layers of defense, successful attacks have only increased in number and severity. Consequently, it is time to re-focus the conventional approach to cyber security. While it is still important to implement measures to keep intruders out, a new protection paradigm is warranted that is aimed at discovering attempted or real compromises as early as possible. Put simply, organizations should take as fact that they have been, are now, or will be compromised. These compromises may be intended to steal information for financial gain as in the theft of intellectual property or credentials that lead to the theft of financial resources, or to lie silent until instructed to cause physical or electronic damage and/or denial of services. This change in outlook has been recently confirmed by the National Security Agency [19]. The discovery of attempted and actual compromises requires an increased focus on monitoring events by manual and/or automated log monitoring, detecting unauthorized changes to a system's hardware and/or software, detecting intrusions, and/or discovering the exfiltration of sensitive information and/or attempts to send inappropriate commands to ICS/SCADA (Industrial Control System/Supervisory Control And Data Acquisition) systems.

  13. RxGen General Optical Model Prescription Generator

    NASA Technical Reports Server (NTRS)

    Sigrist, Norbert

    2012-01-01

    RxGen is a prescription generator for JPL's in-house optical modeling software package called MACOS (Modeling and Analysis for Controlled Optical Systems), which is an expert optical analysis software package focusing on modeling optics on dynamic structures, deformable optics, and controlled optics. The objectives of RxGen are to simplify and automate MACOS prescription generations, reducing errors associated with creating such optical prescriptions, and improving user efficiency without requiring MACOS proficiency. RxGen uses MATLAB (a high-level language and interactive environment developed by MathWorks) as the development and deployment platform, but RxGen can easily be ported to another optical modeling/analysis platform. Running RxGen within the modeling environment has the huge benefit that variations in optical models can be made an integral part of the modeling state. For instance, optical prescription parameters determined as external functional dependencies, optical variations by controlling the in-/exclusion of optical components like sub-systems, and/or controlling the state of all components. Combining the mentioned capabilities and flexibilities with RxGen's optical abstraction layer completely eliminates the hindering aspects for requiring proficiency in writing/editing MACOS prescriptions, allowing users to focus on the modeling aspects of optical systems, i.e., increasing productivity and efficiency. RxGen provides significant enhancements to MACOS and delivers a framework for fast prototyping as well as for developing very complex controlled optical systems.

  14. Transfer matrix method for multibody systems for piezoelectric stack actuators

    NASA Astrophysics Data System (ADS)

    Zhu, Wei; Chen, Gangli; Bian, Leixiang; Rui, Xiaoting

    2014-09-01

    In order to achieve a large displacement output from a piezoelectric actuator, we realized the piezoelectric stack actuator (PSA) by mechanically layering/stacking multi-chip piezoelectric wafers in a series and electrically connecting the electrodes in parallel. In this paper, in order to accurately model the hysteresis and the dynamic characteristics of a PSA, the transfer matrix method for multibody systems (MSTMM) was adopted to describe the dynamic characteristics, and the Bouc-Wen hysteresis operator was used to represent the hysteresis. The vibration characteristics of a PSA and a piezo-actuated positioning mechanism (PPM) are derived and analyzed by the MSTMM; then, the dynamic responses of the PSA and the PPM are calculated. The experimental results show that the new method can accurately portray the hysteresis and the dynamic characteristics of a PSA and a PPM. On one hand, if we use this method to model the dynamic response of the PSA and the PPM, the PSA can be considered as a flexible body, as opposed to a mass-spring-damper system, which is in better agreement with the actual condition. On the other hand, the global dynamics equation is not needed for the study of system dynamics, and the dynamics equation has a small-sized matrix and a higher computational speed. Therefore, this method gives a broad range of possibilities for model-based controller design.

  15. Combating an Epidemic of Prescription Opioid Abuse.

    PubMed

    Pon, Doreen; Awuah, Kwaku; Curi, Danielle; Okyere, Ernest; Stern, Craig S

    2015-11-01

    The past decade has witnessed an alarming increase in the number of deaths due to prescription opioids that has paralleled the rise in the number of opioid prescriptions dispensed. Prescription drug monitoring programs, abuse-deterrent formulations and proper disposal of opioids have been promoted to help combat the opioid epidemic. We discuss changes that dentists, the third most frequent prescribers of opioids, can implement to help reduce the risk of prescription opioid abuse in their communities. PMID:26798885

  16. Combating an Epidemic of Prescription Opioid Abuse.

    PubMed

    Pon, Doreen; Awuah, Kwaku; Curi, Danielle; Okyere, Ernest; Stern, Craig S

    2015-11-01

    The past decade has witnessed an alarming increase in the number of deaths due to prescription opioids that has paralleled the rise in the number of opioid prescriptions dispensed. Prescription drug monitoring programs, abuse-deterrent formulations and proper disposal of opioids have been promoted to help combat the opioid epidemic. We discuss changes that dentists, the third most frequent prescribers of opioids, can implement to help reduce the risk of prescription opioid abuse in their communities.

  17. The Booster to AGS beam transfer fast kicker systems

    SciTech Connect

    Zhang, W.; Bunicci, J.; Soukas, A.V.; Zhang, S.Y.

    1992-01-01

    The Brookhaven AGS Booster has a very successful commissioning period in June 1991. The third phase of that commissioning was a beam extraction test. The Booster extraction fast kicker (F3) deflected a 1.2 GeV proton beam from the Booster circulating orbit into the extraction septum aperture, partially down the extraction line to a temporary beam stop. Now, the Booster is committed to the AGS operations program for both heavy ion and proton beams. Thus, the Booster extraction and the corresponding AGS injection systems must operate routinely up to a pulse repetition frequency of 7.5 Hertz, and up to a beam energy of 1.5 Gev. The injection fast kicker is located in the A5 section of the AGS ring and is used to deflect the proton or heavy ion beam into its final AGS closed orbit. A distinctive feature of the AGS injection fast kicker modulators is the tail-bitting function required for proton beam injection. This enables the system to produce a fast current fall time to go along with the high current pulse amplitude with a fast rise time. The AGS injection fast kicker system has three pulse modulators, and each modulator consists of two thyratrons. The main PFN thyratrons switch on the current, and the tail bitting thyratrons are used to force the magnet current to decrease rapidly. Two digital pulse delay generators are used to align the main thyratrons and the tail bitting thyratrons respectively. The system has been tested and installed. The final commissioning of the Booster to AGS beam transfer line and injection is currently being undertaken. In this article, the system design, realization techniques and performance data will be presented.

  18. The Booster to AGS beam transfer fast kicker systems

    SciTech Connect

    Zhang, W.; Bunicci, J.; Soukas, A.V.; Zhang, S.Y.

    1992-08-01

    The Brookhaven AGS Booster has a very successful commissioning period in June 1991. The third phase of that commissioning was a beam extraction test. The Booster extraction fast kicker (F3) deflected a 1.2 GeV proton beam from the Booster circulating orbit into the extraction septum aperture, partially down the extraction line to a temporary beam stop. Now, the Booster is committed to the AGS operations program for both heavy ion and proton beams. Thus, the Booster extraction and the corresponding AGS injection systems must operate routinely up to a pulse repetition frequency of 7.5 Hertz, and up to a beam energy of 1.5 Gev. The injection fast kicker is located in the A5 section of the AGS ring and is used to deflect the proton or heavy ion beam into its final AGS closed orbit. A distinctive feature of the AGS injection fast kicker modulators is the tail-bitting function required for proton beam injection. This enables the system to produce a fast current fall time to go along with the high current pulse amplitude with a fast rise time. The AGS injection fast kicker system has three pulse modulators, and each modulator consists of two thyratrons. The main PFN thyratrons switch on the current, and the tail bitting thyratrons are used to force the magnet current to decrease rapidly. Two digital pulse delay generators are used to align the main thyratrons and the tail bitting thyratrons respectively. The system has been tested and installed. The final commissioning of the Booster to AGS beam transfer line and injection is currently being undertaken. In this article, the system design, realization techniques and performance data will be presented.

  19. Optical Power Transfer System for Powering a Remote Mobility System for Multiple Missions

    NASA Technical Reports Server (NTRS)

    Stone, William C. (Inventor); Hogan, Bartholomew P. (Inventor)

    2016-01-01

    An optical power transfer system for powering a remote mobility system for multiple missions comprising a high power source and a chilling station connected to a laser source. The laser source transmits a high optical energy to a beam switch assembly via an optical fiber. The beam switch assembly is optically connected to actively cooled fiber spoolers. Docking stations are adapted for securing the fiber spoolers until alternatively ready for use by a remote mobility system. The remote mobility system is optically connected to the fiber spoolers and has a receiving port adapted for securing the fiber spoolers thereon. The fiber spooler transmits the optical energy to a power conversion system which converts the optical energy received to another usable form of energy. More than one power source may be used where the remote mobility system transfers from one source to another while maintaining an operational radius to each source.

  20. 21 CFR 1306.08 - Electronic prescriptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Electronic prescriptions. 1306.08 Section 1306.08... § 1306.08 Electronic prescriptions. (a) An individual practitioner may sign and transmit electronic... an electronic prescription, a pharmacist must include all of the information that this part...

  1. Prescription Drug Abuse and Youth. Information Brief.

    ERIC Educational Resources Information Center

    Department of Justice, Washington, DC. National Drug Intelligence Center.

    Prescription drugs, a category of psychotherapeutics that comprises prescription-type pain relievers, tranquilizers, stimulants, and sedatives, are among the substances most commonly abused by young people in the United States. Prescription drugs are readily available and can easily be obtained by teenagers who abuse these drugs to experience a…

  2. 21 CFR 1306.12 - Refilling prescriptions; issuance of multiple prescriptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Refilling prescriptions; issuance of multiple... multiple prescriptions. (a) The refilling of a prescription for a controlled substance listed in Schedule II is prohibited. (b)(1) An individual practitioner may issue multiple prescriptions authorizing...

  3. Oxygen transfer in the corneal-contact lens system.

    PubMed

    Garr-Peters, J M; Ho, C S

    1987-01-01

    The clinical results of contact lens wearers indicate that materials which theoretically are adequate to prevent corneal hypoxia and edema do not perform optimally under actual wearing conditions. Optimization of the cornea-tear-lens system requires an analysis of the modes of oxygen transport, mass transfer resistances, and characteristic dimensions. The lens properties are a function of polymer composition. Thus, investigations for ideal lens materials may result in limitless test copolymers and graft polymers of siloxane, methylmethacrylate, 2-hydroxyethyl-methacrylate, vinylpyrollidone, vinylacetate, and cellulose acetate butyrate of varying degrees of cross-linking and crystallinity. In an attempt to channel research efforts, this review will state the developments to date and the desirable properties of an optimal cornea-tear-lens system. The logic should encompass a theory and model whereby parameters are identified and varied within satisfactory physiological limitations, and experiments which provide data indicative of the in vivo conditions. The parameters must reflect the inherent transport properties of the corneal-contact lens system. Contact lenses may be categorized as soft, gas-permeable rigid/hydrophobic flexible, or hard. The major differences between these three categories are the properties: equilibrium water content or degree of hydration, tendency for water pervaporation and/or dehydration, surface hydrophobicity, thermal conductivity, oxygen diffusivity and solubility, lens thickness, rest height over corneal tear, flexibility, lens mobility over the cornea, cross-linking, crystallinity, stagnant boundary layer resistances, and manufacturing processes. Aside from complications presented by lens coatings and cleansing solutions, the most common problems experienced by lens wearers include corneal edema, dehydration involving the lens and the cornea, "blurry" vision due to localized corneal anoxia, debris trapped under the lens, and deposits on

  4. Time-Transfer System for Two Orbiting Spacecraft

    NASA Technical Reports Server (NTRS)

    Bertiger, William; Wu, Seen-Chong; Kruizinga, Gerhard; Dunn, Charles; Romans, Larry

    2004-01-01

    A report describes the time-transfer system of the Gravity Recovery and Climate Experiment (GRACE), in which information on the distribution of Earth mass is extracted from position and time measurements for two spacecraft about 200 km apart in a circular, nearly polar orbit. Each spacecraft carriers a Global Positioning System (GPS) receiver, a K/Ka-band ranging (KBR) instrument, and an ultra-stable oscillator (USO) that serves as a clock for the GPS and KBR units. The long-term errors of the USOs are cancelled by use of a technique, called dual-one-way phase measurements, in which the phases of the KBR signals from spacecraft A as measured at spacecraft B are added to the phases of the KBR signals from spacecraft B as measured at spacecraft A. GPS data are used to synchronize time between the USOs to within approximately 150 ps as needed to enable the dual-one-way phase measurements: For each spacecraft, the GPS data are used to solve for orbital positions, and the difference between the onboard clocks and a ground clock every 5 minutes. The relative clock rate between the spacecraft is then determined from the difference between the two solutions.

  5. Transfer entropy in physical systems and the arrow of time.

    PubMed

    Spinney, Richard E; Lizier, Joseph T; Prokopenko, Mikhail

    2016-08-01

    Recent developments have cemented the realization that many concepts and quantities in thermodynamics and information theory are shared. In this paper, we consider a highly relevant quantity in information theory and complex systems, the transfer entropy, and explore its thermodynamic role by considering the implications of time reversal upon it. By doing so we highlight the role of information dynamics on the nuanced question of observer perspective within thermodynamics by relating the temporal irreversibility in the information dynamics to the configurational (or spatial) resolution of the thermodynamics. We then highlight its role in perhaps the most enduring paradox in modern physics, the manifestation of a (thermodynamic) arrow of time. We find that for systems that process information such as those undergoing feedback, a robust arrow of time can be formulated by considering both the apparent physical behavior which leads to conventional entropy production and the information dynamics which leads to a quantity we call the information theoretic arrow of time. We also offer an interpretation in terms of optimal encoding of observed physical behavior. PMID:27627274

  6. Transfer entropy in physical systems and the arrow of time

    NASA Astrophysics Data System (ADS)

    Spinney, Richard E.; Lizier, Joseph T.; Prokopenko, Mikhail

    2016-08-01

    Recent developments have cemented the realization that many concepts and quantities in thermodynamics and information theory are shared. In this paper, we consider a highly relevant quantity in information theory and complex systems, the transfer entropy, and explore its thermodynamic role by considering the implications of time reversal upon it. By doing so we highlight the role of information dynamics on the nuanced question of observer perspective within thermodynamics by relating the temporal irreversibility in the information dynamics to the configurational (or spatial) resolution of the thermodynamics. We then highlight its role in perhaps the most enduring paradox in modern physics, the manifestation of a (thermodynamic) arrow of time. We find that for systems that process information such as those undergoing feedback, a robust arrow of time can be formulated by considering both the apparent physical behavior which leads to conventional entropy production and the information dynamics which leads to a quantity we call the information theoretic arrow of time. We also offer an interpretation in terms of optimal encoding of observed physical behavior.

  7. BPM SYSTEM FOR THE SNS RING AND TRANSFER LINES.

    SciTech Connect

    DAWSON,W.C.; CAMERON,P.; CERNIGLIA,P.; CUPOLO,J.; DEGEN,C.; DELLAPENNA,A.; HUHN,A.; KESSELMAN,M.; MEAD,J.; SIKORA,R.

    2002-05-06

    The Spallation Neutron Source Ring accumulates about 1060 pulses of 38mA peak current IGeV H-minus particles from the Linac thru the HEBT line, then delivers this accumulated beam in a single pulse to the mercury target via the RTBT line. Bunching frequency of beam in the HEBT line is 402.5MHz, and about 1MHz in the Ring and RTBT. Position monitor electrodes in HEBT are of the shorted stripline type, with apertures of 12cm except in the dispersive bend, where the aperture is 21cm. Ring and RTBT electrodes are open striplines, with apertures of 21, 26, 30, and 36cm. All pickups are dual plane. The electronics will be PC-based with the Analog/Digital Front End passing data and receiving control and timing thru a custom PC1 interface developed by LANL[l]. LabVIEW will be used to direct the acquisition, process the data, and transfer results via Ethernet to the EPICS control system. To handle the dynamic range required with well over 60dB variation in signal size, the Ring and RTBT electronics will employ a fast gain switching technique that will take advantage of the 300ns tail-to-head gap to provide position measurement during the entire accumulation cycle. Beam-based alignment will be utilized as part of the system calibration.

  8. Demonstration of the smart crane ammunition transfer system

    SciTech Connect

    Bradley, E.C.; Killough, S.M.; Rowe, J.C.

    1996-05-01

    The purpose of the Smart Crane Ammunition Transfer System (SCATS) project is to demonstrate robotic/telerobotic controls technology for a mobile articulated crane for missile/munitions handling, delivery, and reload. Missile resupply and reload have been manually intensive operations up to this time. Currently, reload missiles are delivered by truck to the site of the launcher. A crew of four to five personnel reloads the missiles from the truck to the launcher using a hydraulic-powered crane. The missiles are handled carefully for the safety of the missiles and personnel. Numerous steps are required in the reload process and the entire reload operation can take over an hour for some missile systems. Recent US Army directives require the entire operation to be accomplished in a fraction of that time. Current development of SCATS is being based primarily on reloading Patriot missiles. This paper summarizes the current status of the SCATS project at the Oak Ridge National Laboratory (ORNL). Additional information on project background and requirements has been described previously (Bradley, et al., 1995).

  9. Analysis of prescription database extracted from standard textbooks of traditional Dai medicine

    PubMed Central

    2012-01-01

    Background Traditional Dai Medicine (TDM) is one of the four major ethnomedicine of China. In 2007 a group of experts produced a set of seven Dai medical textbooks on this subject. The first two were selected as the main data source to analyse well recognized prescriptions. Objective To quantify patterns of prescriptions, common ingredients, indications and usages of TDM. Methods A relational database linking the prescriptions, ingredients, herb names, indications, and usages was set up. Frequency of pattern of combination and common ingredients were tabulated. Results A total of 200 prescriptions and 402 herbs were compiled. Prescriptions based on "wind" disorders, a detoxification theory that most commonly deals with symptoms of digestive system diseases, accounted for over one third of all prescriptions. The major methods of preparations mostly used roots and whole herbs. Conclusion The information extracted from the relational database may be useful for understanding symptomatic treatments. Antidote and detoxification theory deserves further research. PMID:22931752

  10. Advanced Life Support Systems: Opportunities for Technology Transfer

    NASA Technical Reports Server (NTRS)

    Fields, B.; Henninger, D.; Ming, D.; Verostko, C. E.

    1994-01-01

    NASA's future missions to explore the solar system will be of long-duration possibly lasting years at a time. Human life support systems will have to operate with very high reliability for these long periods with essentially no resupply from Earth. Such life support systems will make extensive use of higher plants, microorganisms, and physicochemical processes for recycling air and water, processing wastes, and producing food. Development of regenerative life support systems will be a pivotal capability for NASA's future human missions. A fully functional closed loop human life support system currently does not exist and thus represents a major technical challenge for space exploration. Technologies where all life support consumables are recycled have many potential terrestrial applications as well. Potential applications include providing human habitation in hostile environments such as the polar regions or the desert in such a way as to minimize energy expenditures and to minimize negative impacts on those often ecologically-sensitive areas. Other potential applications include production of food and ornamental crops without damaging the environment from fertilizers that contaminate water supplies; removal of trace gas contaminants from tightly sealed, energy-efficient buildings (the so-called sick building syndrome); and even the potential of gaining insight into the dynamics of the Earth's biosphere such that we can better manage our global environment. Two specific advanced life support technologies being developed by NASA, with potential terrestrial application, are the zeoponic plant growth system and the Hybrid Regenerative Water Recovery System (HRWRS). The potential applications for these candidate dual use technologies are quite different as are the mechanisms for transfer. In the case of zeoponics, a variety of commercial applications has been suggested which represent potentially lucrative markets. Also, the patented nature of this product offers

  11. Accuracy in prescriptions compounded by pharmacy students.

    PubMed

    Shrewsbury, R P; Deloatch, K H

    1998-01-01

    Most compounded prescriptions are not analyzed to determine the accuracy of the employed instruments and procedures. The assumption is that the compounded prescription will be +/- 5% the labeled claim. Two classes of School of Pharmcacy students who received repeated instruction and supervision on proper compounding techniques and procedures were assessed to determine their accuracy of compounding a diphenhydramine hydrochloride prescription. After two attempts, only 62% to 68% of the students could compound the prescription within +/- 5% the labeled claim; but 84% to 96% could attain an accuracy of +/- 10%. The results suggest that an accuracy of +/- 10% labeled claim is the least variation a pharmacist can expect when extemporaneously compounding prescriptions.

  12. INTRAMOLECULAR CHARGE AND ENERGY TRANSFER IN MULTICHROMOPHORIC AROMATIC SYSTEMS

    SciTech Connect

    Edward C. Lim

    2008-09-09

    A concerted experimental and computational study of energy transfer in nucleic acid bases and charge transfer in dialkylaminobenzonitriles, and related electron donor-acceptor molecules, indicate that the ultrafast photoprocesses occur through three-state conical interactions involving an intermediate state of biradical character.

  13. [Electronic prescription in Catalonia, Spain (Rec@t): a health tool].

    PubMed

    Gilabert-Perramon, Antoni; López-Calahorra, Pilar; Escoda-Geli, Núria; Salvadó-Trias, Clara

    2010-02-01

    Electronic prescription is new advance in the use of new technologies on health care. It is a tool that increases quality health care, patient's accessibility and safety in use of drugs and sustainability of the system. Electronic prescription is also a system of prescribing and dispensing in real time, improving coordination between health professionals. The electronic prescription model establishes that the patient comes to the health center where physician diagnostics, makes prescriptions of treatment and, if it is necessary, gives a medication plan to the patient. This medication plan contains currents treatments and a security code. Patients can go to any pharmacy he wants and have to present medication plan and health care card for drug delivery. The electronic prescription is being implemented gradually in Catalonia; Barcelona city is the last zone where Electronic prescription is being implemented. On November, more than 3.100 physicians, 2.450 pharmacies and 870.000 patients are using electronic prescriptions normally and without any remarkable incidences and more than 90.000 drugs are being dispensed every day. Implementation of electronic prescription project is a success in Catalonia, with a good reception from professionals and patients. The model of electronic prescription improves every day to be more useful to professionals and patients.

  14. Prescription drug abuse: problem, policies, and implications.

    PubMed

    Phillips, Janice

    2013-01-01

    This article provides an overview on prescription drug abuse and highlights a number of related legislative bills introduced during the 112th Congress in response to this growing epidemic. Prescription drug abuse has emerged as the nation's fastest growing drug problem. Although prescription drugs have been used effectively and appropriately for decades, deaths from prescription pain medicine in particular have reached epidemic proportions. Bills related to prescription drug abuse introduced during the 112th Congress focus on strengthening provider and consumer education, tracking and monitoring prescription drug abuse, improving data collection on drug overdose fatalities, combating fraud and abuse in Medicare and Medicaid programs, reclassifying drugs to make them more difficult to prescribe and obtain, and enforcing stricter penalties for individuals who operate scam pain clinics and sell pain pills illegitimately. This article underscores the importance of a multifaceted approach to combating prescription drug abuse and concludes with implications for nursing. PMID:23245611

  15. The Influence of Transfer System Factors and Training Elapsed Time on Transfer in a Healthcare Organization

    ERIC Educational Resources Information Center

    Mihalko, Beverly J.

    2010-01-01

    Organizations and other sponsors of training face increasing pressure to demonstrate the value or impact of their training programs on individual and organizational performance. A critical element in the validation of training effectiveness is the permanent transfer of learned knowledge, skills, and behaviors to the workplace. The generalization…

  16. Rational Prescription for a Dermatologist

    PubMed Central

    Prakash, Bhanu; Nadig, Prathiba; Nayak, Amitha

    2016-01-01

    The ultimate goal in dermatological therapy is to use the safest and least number of drugs in order to obtain the best possible effect in the shortest period and at reasonable cost. Rational drug use (RDU) is conventionally defined as the use of an appropriate, efficacious, safe and cost-effective drug given for the right indications in the right dose and formulation, at right time intervals. WHO estimates that more than half of all medicines are prescribed, dispensed or sold inappropriately, and that half of all patients fail to take them correctly as prescribed by the doctor. The process of Rational prescription for a Dermatologist (RPD) involves a series of steps such as defining the patient's illness, specifying the treatment objectives, using the principle of P-treatment, starting the treatment, providing appropriate information and monitoring the treatment. Reasons for irrational prescription could be physician related, patient related, industry related, regulations related. Practicing medicine irrationally can lead to disastrous events like increased morbidity and mortality, drain of resources, drug resistance etc. Principles to enhance the RDU in our practice and minimize errors of prescription are discussed in detail in this article. PMID:26955092

  17. Rational Prescription for a Dermatologist.

    PubMed

    Prakash, Bhanu; Nadig, Prathiba; Nayak, Amitha

    2016-01-01

    The ultimate goal in dermatological therapy is to use the safest and least number of drugs in order to obtain the best possible effect in the shortest period and at reasonable cost. Rational drug use (RDU) is conventionally defined as the use of an appropriate, efficacious, safe and cost-effective drug given for the right indications in the right dose and formulation, at right time intervals. WHO estimates that more than half of all medicines are prescribed, dispensed or sold inappropriately, and that half of all patients fail to take them correctly as prescribed by the doctor. The process of Rational prescription for a Dermatologist (RPD) involves a series of steps such as defining the patient's illness, specifying the treatment objectives, using the principle of P-treatment, starting the treatment, providing appropriate information and monitoring the treatment. Reasons for irrational prescription could be physician related, patient related, industry related, regulations related. Practicing medicine irrationally can lead to disastrous events like increased morbidity and mortality, drain of resources, drug resistance etc. Principles to enhance the RDU in our practice and minimize errors of prescription are discussed in detail in this article. PMID:26955092

  18. Numerical heat transfer attic model using a radiant barrier system

    SciTech Connect

    Moujaes, S.F.; Alsaiegh, N.T.

    2000-04-01

    A two-dimensional, steady-state finite-element model was developed to simulate the thermal effects of the application of an attic radiant barrier system (ARBS) inside a ventilated residential attic. The attic is ventilated using the exhaust air from an evaporative cooler. The study uses a {kappa}-{epsilon} turbulent model to describe the velocity and temperature distributions in the attic. The ambient temperature and solar isolation densities on the outside inclined attic surfaces are used as driving functions for the model. The model also included the appropriate heat exchange modes of convection and radiation on these outside surfaces. Several recirculation zones were visually observed in the attic flow pattern. Also, the use of the ARBS seems to lower the heat transfer through the ceiling by 25--30%, but this effect decreases significantly as the outside ventilation rates are increased through the attic space. The 2D model revealed some interesting temperature distributions along the attic surfaces that could not have been predicted by the one-dimensional models. The lower emissivity ARBS seems to raise the temperature of the inclined attic surfaces as well as the temperature of the exhausted ventilation air.

  19. The GNC Measurement System for the Automated Transfer Vehicle

    NASA Astrophysics Data System (ADS)

    Roux, Y.; da Cunha, P.

    The Automated Transfer Vehicle (ATV) is a European Space Agency (ESA) funded spacecraft developed by EADS Space Transportation as prime contractor for the space segment together with major European industrial partners, in the frame of the International Space Station (ISS). Its mission objective is threefold : to supply the station with fret and propellant, to reboost ISS to a higher orbit and to dispose of waste from the station. The ATV first flight, called Jules Verne and planned on 2005, will be the first European Vehicle to perform an orbital rendezvous. The GNC Measurement System (GMS) is the ATV on board function in charge of the measurement data collection and preconditioning for the navigation, guidance and control (GNC) algorithms. The GMS is made up of hardware which are the navigation sensors (with a certain level of hardware redundancy for each of them), and of an on-board software that manages, monitors and performs consistency checks to detect and isolate potential sensor failures. The GMS relies on six kinds of navigation sensors, used during various phases of the mission : the gyrometers assembly (GYRA), the accelerometers assembly (ACCA), the star trackers (STR), the GPS receivers, the telegoniometers (TGM) and the videometers (VDM), the last two being used for the final rendezvous phase. The GMS function is developed by EADS Space Transportation together with other industrial partners: EADS Astrium, EADS Sodern, Laben and Dasa Jena Optronik.

  20. Molten Chloride Salts for Heat Transfer in Nuclear Systems

    NASA Astrophysics Data System (ADS)

    Ambrosek, James Wallace

    2011-12-01

    A forced convection loop was designed and constructed to examine the thermal-hydraulic performance of molten KCl-MgCl2 (68-32 at %) salt for use in nuclear co-generation facilities. As part of this research, methods for prediction of the thermo-physical properties of salt mixtures for selection of the coolant salt were studied. In addition, corrosion studies of 10 different alloys were exposed to the KCl-MgCl2 to determine a suitable construction material for the loop. Using experimental data found in literature for unary and binary salt systems, models were found, or developed to extrapolate the available experimental data to unstudied salt systems. These property models were then used to investigate the thermo-physical properties of the LINO3-NaNO3-KNO 3-Ca(NO3), system used in solar energy applications. Using these models, the density, viscosity, adiabatic compressibility, thermal conductivity, heat capacity, and melting temperatures of higher order systems can be approximated. These models may be applied to other molten salt systems. Coupons of 10 different alloys were exposed to the chloride salt for 100 hours at 850°C was undertaken to help determine with which alloy to construct the loop. Of the alloys exposed, Haynes 230 had the least amount of weight loss per area. Nickel and Hastelloy N performed best based on maximum depth of attack. Inconel 625 and 718 had a nearly uniform depletion of Cr from the surface of the sample. All other alloys tested had depletion of Cr along the grain boundaries. The Nb in Inconel 625 and 718 changed the way the Cr is depleted in these alloys. Grain-boundary engineering (GBE) of Incoloy 800H improved the corrosion resistance (weight loss and maximum depth of attack) by nearly 50% as compared to the as-received Incoloy 800H sample. A high temperature pump, thermal flow meter, and pressure differential device was designed, constructed and tested for use in the loop, The heat transfer of the molten chloride salt was found to

  1. An Evidence-Based Approach To Exercise Prescriptions on ISS

    NASA Technical Reports Server (NTRS)

    Ploutz-Snyder, Lori

    2009-01-01

    This presentation describes current exercise countermeasures and exercise equipment for astronauts onboard the ISS. Additionally, a strategy for evaluating evidence supporting spaceflight exercise is described and a new exercise prescription is proposed. The current exercise regimen is not fully effective as the ISS exercise hardware does not allow for sufficient exercise intensity, the exercise prescription is adequate and crew members are noncompliant with the prescription. New ISS hardware is proposed, Advanced Resistance Exercise Device (ARED), which allows additional exercises, is instrumented for data acquisition and offers improved loading. The new T2 hardware offers a better harness and subject loading system, is instrumented to allow ground reaction force data, and offers improved speed. A strategy for developing a spaceflight exercise prescription is described and involves identifying exercise training programs that have been shown to maximize adaptive benefits of people exercising in both 0 and 1 g environments. Exercise intensity emerged as an important factor in maintaining physiologic adaptations in the spaceflight environment and interval training is suggested. New ISS exercise hardware should allow for exercise at intensities high enough to elicit adaptive responses. Additionally, new exercise prescriptions should incorporate higher intensity exercises and seek to optimize intensity, duration and frequency for greater efficiency.

  2. Prescription errors in Brazilian hospitals: a multi-centre exploratory survey.

    PubMed

    Miasso, Adriana Inocenti; Oliveira, Regina Célia de; Silva, Ana Elisa Bauer de Camargo; Lyra Junior, Divaldo Pereira de; Gimenes, Fernanda Raphael Escobar; Fakih, Flávio Trevisan; Cassiani, Sílvia Helena De Bortoli

    2009-02-01

    In Brazil, millions of prescriptions do not follow the legal requirements necessary to guarantee the correct dispensing and administration of medication. This multi-centre exploratory study aimed to analyze the appropriateness of prescriptions at four Brazilian hospitals and to identify possible errors caused by inadequacies. The sample consisted of 864 prescriptions obtained at hospital medical clinics in January 2003. Data was collected by three nurse researchers during one week using a standard data sheet that included items about: the type of prescription; legibility; completeness; use of abbreviations; existence of changes and erasures. There were statistically significant differences between incomplete electronic prescriptions at hospital A, and handwritten ones from hospitals C (C2 = 12.703 and p < 0.001) and D (C2 = 14.074 and p < 0.001). Abbreviations were used in more than 80% of prescriptions at hospitals B, C and D. Changes were found in prescriptions at all hospitals, with higher levels at hospitals B (35.2%) and A (25.3%). This study identified a range of vulnerable points in the prescription phase of the medication system at the hospitals. Physicians, pharmacists and nurses should therefore jointly propose strategies to avoid these prescription errors. PMID:19219238

  3. Prescription errors in Brazilian hospitals: a multi-centre exploratory survey.

    PubMed

    Miasso, Adriana Inocenti; Oliveira, Regina Célia de; Silva, Ana Elisa Bauer de Camargo; Lyra Junior, Divaldo Pereira de; Gimenes, Fernanda Raphael Escobar; Fakih, Flávio Trevisan; Cassiani, Sílvia Helena De Bortoli

    2009-02-01

    In Brazil, millions of prescriptions do not follow the legal requirements necessary to guarantee the correct dispensing and administration of medication. This multi-centre exploratory study aimed to analyze the appropriateness of prescriptions at four Brazilian hospitals and to identify possible errors caused by inadequacies. The sample consisted of 864 prescriptions obtained at hospital medical clinics in January 2003. Data was collected by three nurse researchers during one week using a standard data sheet that included items about: the type of prescription; legibility; completeness; use of abbreviations; existence of changes and erasures. There were statistically significant differences between incomplete electronic prescriptions at hospital A, and handwritten ones from hospitals C (C2 = 12.703 and p < 0.001) and D (C2 = 14.074 and p < 0.001). Abbreviations were used in more than 80% of prescriptions at hospitals B, C and D. Changes were found in prescriptions at all hospitals, with higher levels at hospitals B (35.2%) and A (25.3%). This study identified a range of vulnerable points in the prescription phase of the medication system at the hospitals. Physicians, pharmacists and nurses should therefore jointly propose strategies to avoid these prescription errors.

  4. Prescription Extraction from Clinical Notes: Towards Automating EMR Medication Reconciliation

    PubMed Central

    Wang, Yajuan; Steinhubl, Steven R.; Defilippi, Chrisopher; Ng, Kenney; Ebadollahi, Shahram; Stewart, Walter F.; Byrd, Roy J

    2015-01-01

    Medication in for ma lion is one of [he most important clinical data types in electronic medical records (EMR) This study developed an NLP application (PredMED) to extract full prescriptions and their relevant components from a large corpus of unstructured ambulatory office visit clinical notes and the corresponding structured medication reconciliation (MED REC) data in the EMR. PredMED achieved an 84.4% F-score on office visit encounter notes and 95.0% on MED„REC data, outperforming two available medication extraction systems. To assess the potential for using automatically extracted prescriptions in the medication reconciliation task, we manually analyzed discrepancies between prescriptions found in clinical encounter notes and in matching MED_REC data for sample patient encounters. PMID:26306266

  5. Simulation of Gravity Feed Oil for Areoplane Fuel Transfer System

    NASA Astrophysics Data System (ADS)

    Lv, Y. G.; Liu, Z. X.; Huang, S. Q.; Xu, T.

    Generally, it has two different ways for fuel transfer for areoplane, the simplest one is by gravity, and another is by pumps. But the simplest one mighte change to the vital method in some situation, such as electrical and mechanical accident. So the study of gravity feed oil is aslo important. Past calculations assumed that, under gravity feed, only one fuel tank in aircraft supplies the fuel needed for preventing extremely serious accident to happen. Actually, gravity feed oil is a transient process, all fuel tanks compete for supplying oil and there must have several fuel tanks offering oil simultaneously. The key problems to calculate gravity feed oil are the sumulation of the multiple-branch and transient process. Firstly, we presented mathematical models for oil flow through pipes, non-working pupms and check valves, ect. Secondly, On the basis of flow network theory and time difference method, we established a new calculation method for gravity feed oil of aeroplane fuel system. This model can solve the multiple-branch and transient process simulation of gravity feed oil. Our method takes into consideration all fuel tanks and therefore, we believe, our method is intrinsically superior to traditional methods and is closer to understanding the real seriousness of the oil supply situation. Finally, we give a numerical example using the new method for a certain type of aircraft under gravity feed. achieved the variations of oil level and flow mass per second of each oil tanks which showed in Figures below. These variations show preliminarily that our proposed method of calculations is satisfactory.

  6. Who Cares What It Costs to Dispense a Medicaid Prescription?

    PubMed Central

    Lamphere-Thorpe, Jo Ann; Johnston, William P.; Kilpatrick, Kerry E.; Norwood, G. Joseph

    1994-01-01

    Results of a 1992 Medicaid cost-of-dispensing study among North Carolina pharmacies are presented. The estimated statewide weighted average cost incurred by pharmacies to dispense a prescription was $5.37 in 1991. The variation in dispensing costs found among pharmacies of various sizes, organizational types, and locations is identified. Higher average dispensing costs were reported for large chain pharmacies and those pharmacies in urban areas. Considering the potential for expanded prescription drug benefits under a reformed health care system, the implications of the study's findings for pharmacy payment policy are discussed. PMID:10137800

  7. 40 CFR 60.254 - Standards for coal processing and conveying equipment, coal storage systems, transfer and loading...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... conveying equipment, coal storage systems, transfer and loading systems, and open storage piles. 60.254... systems, transfer and loading systems, and open storage piles. (a) On and after the date on which the... conveying equipment, coal storage system, or coal transfer and loading system processing coal...

  8. Attrition, Retention, and Transfer within the Kentucky System of Public Higher Education.

    ERIC Educational Resources Information Center

    Mann, Ronald A.; Walker, J. Kenneth

    Results of a recent study of attrition, retention, and transfer within the system of public higher education in Kentucky are summarized. Attrition, retention, and transfer rates are presented by class level and institution for 1979-80. For first-time full-time freshmen, the university system had an attrition rate of 27.9 percent, ranging from 20.6…

  9. Changes to the Transfer Line Collimation System for the High-Luminosity LHC Beams

    SciTech Connect

    Kain, V.; Aberle, O.; Bracco, C.; Fraser, M.; Galleazzi, F.; Gianfelice-Wendt, E.; Kosmicki, A.; Maciariello, F.; Meddahi, M.; Nuiry, F. X.; Steele, G.; Velotti, F.

    2015-06-01

    The current LHC transfer line collimation system will not be able to provide enough protection for the high brightness beams in the high-luminosity LHC era. The new collimation system will have to attenuate more and be more robust than its predecessor. The active jaw length of the new transfer line collimators will therefore be 2.1 m instead of currently 1.2 m. The transfer line optics will have to be adjusted for the new collimator locations and larger beta functions at the collimators for absorber robustness reasons. In this paper the new design of the transfer line collimation system will be presented with its implications on transfer line optics and powering, maintainability, protection of transfer line magnets in case of beam loss on a collimator and protection of the LHC aperture.

  10. Orbital transfer vehicle concept definition and system analysis study, 1985. Volume 3: System and program trades

    NASA Technical Reports Server (NTRS)

    Nelson, James H.; Mohrman, Gordon W.; Callan, Daniel R.

    1986-01-01

    The key system and program trade studies performed to arrive at a preferred Orbital Transfer Vehicle (OTV) system concept and evolutionary approach to the acquisition of the requisite capabilites is documented. These efforts were expanded to encompass a Space Transportation Architecture Study (STAS) mission model and recommended unmanned cargo vehicle. The most important factors affecting the results presented are the mission model requirements and selection criteria. The reason for conducting the OTV concept definition and system analyses study is to select a concept and acquisition approach that meets a delivery requirement reflected by the mission model.

  11. 21 CFR 1306.22 - Refilling of prescriptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... as the computer system is available for use again. (g) When filing refill information for original... information must be retrievable by the prescription number: (1) The name and dosage form of the controlled... computer application may be used for the storage and retrieval of refill information for original...

  12. 21 CFR 1306.22 - Refilling of prescriptions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... as the computer system is available for use again. (g) When filing refill information for original... information must be retrievable by the prescription number: (1) The name and dosage form of the controlled... computer application may be used for the storage and retrieval of refill information for original...

  13. Medical and Nonmedical Users of Prescription Drugs among College Students

    ERIC Educational Resources Information Center

    Rozenbroek, Katelyn; Rothstein, William G.

    2011-01-01

    Objectives: To examine medical and nonmedical users of prescription opioids, central nervous system depressants, and stimulants taken individually and in combination. Participants: Undergraduates at an urban mid-Atlantic university with 12,000 students. Methods: A questionnaire administered in classes provided 413 responses, with a usable response…

  14. [Adverse drug reactions reporting is helping "non substituable" prescription!].

    PubMed

    Jacquot, Julien; Bagheri, Haleh; Montastruc, Jean-Louis

    2014-01-01

    In August 2012, general practitioners of Haute- Garonne received a letter from Health insurance system, informing that prescriptions could be endorsed by "not substituable" after reporting an adverse drug reactions (ADR). Compared to an equivalent period before this letter, we observed an increase of ADRs reports for generics, mainly concerning gastrointestinal ADR and lack of efficacy. PMID:24927508

  15. 33 CFR 149.130 - What are the requirements for the cargo transfer system alarm?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... EQUIPMENT Pollution Prevention Equipment § 149.130 What are the requirements for the cargo transfer system... system. (b) The alarm must sound automatically in the control room and: (1) Be capable of being...

  16. Estimating Heat and Mass Transfer Processes in Green Roof Systems: Current Modeling Capabilities and Limitations (Presentation)

    SciTech Connect

    Tabares Velasco, P. C.

    2011-04-01

    This presentation discusses estimating heat and mass transfer processes in green roof systems: current modeling capabilities and limitations. Green roofs are 'specialized roofing systems that support vegetation growth on rooftops.'

  17. Onsets of hierarchy truncation and self-consistent Born approximation with quantum mechanics prescriptions invariance.

    PubMed

    Zhang, Hou-Dao; Yan, YiJing

    2015-12-01

    The issue of efficient hierarchy truncation is related to many approximate theories. In this paper, we revisit this issue from both the numerical efficiency and quantum mechanics prescription invariance aspects. The latter requires that the truncation approximation made in Schrödinger picture, such as the quantum master equations and their self-consistent-Born-approximation improvements, should be transferable to their Heisenberg-picture correspondences, without further approximations. We address this issue with the dissipaton equation of motion (DEOM), which is a unique theory for the dynamics of not only reduced systems but also hybrid bath environments. We also highlight the DEOM theory is not only about how its dynamical variables evolve in time, but also the underlying dissipaton algebra. We demonstrate this unique feature of DEOM with model systems and report some intriguing nonlinear Fano interferences characteristics that are experimentally measurable.

  18. Onsets of hierarchy truncation and self-consistent Born approximation with quantum mechanics prescriptions invariance.

    PubMed

    Zhang, Hou-Dao; Yan, YiJing

    2015-12-01

    The issue of efficient hierarchy truncation is related to many approximate theories. In this paper, we revisit this issue from both the numerical efficiency and quantum mechanics prescription invariance aspects. The latter requires that the truncation approximation made in Schrödinger picture, such as the quantum master equations and their self-consistent-Born-approximation improvements, should be transferable to their Heisenberg-picture correspondences, without further approximations. We address this issue with the dissipaton equation of motion (DEOM), which is a unique theory for the dynamics of not only reduced systems but also hybrid bath environments. We also highlight the DEOM theory is not only about how its dynamical variables evolve in time, but also the underlying dissipaton algebra. We demonstrate this unique feature of DEOM with model systems and report some intriguing nonlinear Fano interferences characteristics that are experimentally measurable. PMID:26646874

  19. Onsets of hierarchy truncation and self–consistent Born approximation with quantum mechanics prescriptions invariance

    SciTech Connect

    Zhang, Hou-Dao; Yan, YiJing

    2015-12-07

    The issue of efficient hierarchy truncation is related to many approximate theories. In this paper, we revisit this issue from both the numerical efficiency and quantum mechanics prescription invariance aspects. The latter requires that the truncation approximation made in Schrödinger picture, such as the quantum master equations and their self–consistent–Born–approximation improvements, should be transferable to their Heisenberg–picture correspondences, without further approximations. We address this issue with the dissipaton equation of motion (DEOM), which is a unique theory for the dynamics of not only reduced systems but also hybrid bath environments. We also highlight the DEOM theory is not only about how its dynamical variables evolve in time, but also the underlying dissipaton algebra. We demonstrate this unique feature of DEOM with model systems and report some intriguing nonlinear Fano interferences characteristics that are experimentally measurable.

  20. Primary propulsion of electrothermal, ion and chemical systems for space-based radar orbit transfer

    NASA Technical Reports Server (NTRS)

    Wang, S. Y.; Staiger, P. J.

    1985-01-01

    An orbit transfer mission concept has been studied for a Space-Based Radar (SBR) where 40 kW required for radar operation is assumed available for orbit transfer propulsion. Arcjet, pulsed electrothermal (PET), ion, and storable chemical systems are considered for the primary propulsion. Transferring two SBR per shuttle flight to 1112 km/60 deg using electrical propulsion systems offers an increased payload at the expense of increased trip time, up to 2000 kg each, which may be critical for survivability. Trade offs between payload mass, transfer time, launch site, inclination, and height of parking orbits are presented.

  1. Primary propulsion of electrothermal, ion, and chemical systems for space-based radar orbit transfer

    NASA Technical Reports Server (NTRS)

    Wang, S.-Y.; Staiger, P. J.

    1985-01-01

    An orbit transfer mission concept has been studied for a Space-Based Radar (SBR) where 40 kW required for radar operation is assumed available for orbit transfer propulsion. Arcjet, pulsed electrothermal (PET), ion, and storable chemical systems are considered for the primary propulsion. Transferring two SBR per shuttle flight to 1112 km/60 deg using eiectrical propulsion systems offers an increased payload at the expense of increased trip time, up to 2000 kg each, which may be critical for survivability. Trade offs between payload mass, transfer time, launch site, inclination, and height of parking orbits are presented.

  2. Enhanced two phase flow in heat transfer systems

    DOEpatents

    Tegrotenhuis, Ward E; Humble, Paul H; Lavender, Curt A; Caldwell, Dustin D

    2013-12-03

    A family of structures and designs for use in devices such as heat exchangers so as to allow for enhanced performance in heat exchangers smaller and lighter weight than other existing devices. These structures provide flow paths for liquid and vapor and are generally open. In some embodiments of the invention, these structures can also provide secondary heat transfer as well. In an evaporate heat exchanger, the inclusion of these structures and devices enhance the heat transfer coefficient of the evaporation phase change process with comparable or lower pressure drop.

  3. CORRELATING ELECTRONIC AND VIBRATIONAL MOTIONS IN CHARGE TRANSFER SYSTEMS

    SciTech Connect

    Khalil, Munira

    2014-06-27

    The goal of this research program was to measure coupled electronic and nuclear motions during photoinduced charge transfer processes in transition metal complexes by developing and using novel femtosecond spectroscopies. The scientific highlights and the resulting scientific publications from the DOE supported work are outlined in the technical report.

  4. Segment Transfer: A Consequence of a Dynamic System.

    ERIC Educational Resources Information Center

    Hancin-Bhatt, Barbara

    1994-01-01

    Discusses theoretical explanations of segment transfer in early second-language learning, focusing on the issue of differential substitution. The Feature Competition Model is based on an algorithm for the calculation of feature prominences in the first language based on the principles of underspecification. (62 references) (MDM)

  5. Heat transfer in inertial confinement fusion reactor systems

    SciTech Connect

    Hovingh, J.

    1980-04-23

    The short time and deposition distance for the energy from inertial fusion products results in local peak power densities on the order of 10/sup 18/ watts/m/sup 3/. This paper presents an overview of the various inertial fusion reactor designs which attempt to reduce these peak power intensities and describes the heat transfer considerations for each design.

  6. 26 CFR 1.1081-6 - Transfers within system group.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 1.1081-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Exchanges in Obedience to S.e.c. Orders § 1.1081-6 Transfers... gain of the B Corporation reflected in the retirement will therefore be recognized. (e) No exchange...

  7. 26 CFR 1.1081-6 - Transfers within system group.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 1.1081-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Exchanges in Obedience to S.e.c. Orders § 1.1081-6 Transfers... gain of the B Corporation reflected in the retirement will therefore be recognized. (e) No exchange...

  8. 26 CFR 1.1081-6 - Transfers within system group.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 1.1081-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Exchanges in Obedience to S.e.c. Orders § 1.1081-6 Transfers... gain of the B Corporation reflected in the retirement will therefore be recognized. (e) No exchange...

  9. 26 CFR 1.1081-6 - Transfers within system group.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 1.1081-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Exchanges in Obedience to S.e.c. Orders § 1.1081-6 Transfers... gain of the B Corporation reflected in the retirement will therefore be recognized. (e) No exchange...

  10. Design of Wireless Power Transfer System Using E-class Amplifier

    NASA Astrophysics Data System (ADS)

    Zhang, Le; Zhang, Yuan; Zhu, Wu; Huang, Jing

    2016-05-01

    This paper mainly discuss the wireless power transfer system based on class-E amplifier. Firstly, the system coupling model was established and the working principle and parameter design of class-E amplifier was analyzed in detail. Then proposed a method of high frequency driver design using high frequency power transistor push-pull mode. On this basis, we successfully designed and built the wireless power transfer system. The maximum transmission power is 15W and the transmission distance is 20cm. The method of class-E amplifier is verified in wireless power transfer system.

  11. Heat transfer coefficients in two-dimensional Yukawa systems (numerical simulations)

    SciTech Connect

    Khrustalyov, Yu. V. Vaulina, O. S.

    2013-05-15

    New data on heat transfer in two-dimensional Yukawa systems have been obtained. The results of a numerical study of the thermal conductivity for equilibrium systems with parameters close to the conditions of laboratory experiments in dusty plasma are presented. The Green-Kubo relations are used to calculate the heat transfer coefficients. The influence of dissipation (internal friction) on the heat transfer processes in nonideal systems is studied. New approximations are proposed for the thermal conductivity and diffusivity for nonideal dissipative systems. The results obtained are compared with the existing experimental and numerical data.

  12. 21 CFR 1311.120 - Electronic prescription application requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Electronic prescription application requirements... REQUIREMENTS FOR ELECTRONIC ORDERS AND PRESCRIPTIONS Electronic Prescriptions § 1311.120 Electronic prescription application requirements. (a) A practitioner may only use an electronic prescription...

  13. A heat transfer model for biological wastewater treatment system

    NASA Astrophysics Data System (ADS)

    Lin, S. H.

    A heat transfer model for predicting the water temperature of aeration tank in a biological wastewater treatment plant is presented. The heat transfer mechanisms involved in the development of the heat transfer model include heat gains from solar radiation and biochemical reaction and heat losses from evaporation, aeration, wind blowing and conduction through tank walls. Several empirical correlations were adopted and appropriate assumptions made to facilitate the model development. Experiments were conducted in the biological wastewater treatment plant of a chemical fiber company over a year's period. The operational, weather and temperature data were registered. The daily water temperature data were averaged over a month period and compared with the theoretical prediction. Excellent agreement has been obtained between the predicted and measured temperatures, verifying the proposed heat transfer model. Zusammenfassung Es wird ein Wärmeübergangsmodell zur Berechnung der Wassertemperatur im Belüftungstank einer Anlage zur biologischen Abwasserbehandlung vorgestellt. Die in das Modell eingehenden Wärmeübergangsmechanismen umfassen: solare Wärmeeinstrahlung, biochemische Reaktion, Wärmeverluste durch Verdampfung, Belüftung, Windeinfluß und Leitung durch die Behälterwände. Mehrere empirische Beziehungen sowie vertretbare Annahmen tragen zur Modellvereinfachung bei. An der biologischen Abwasser-Kläranlage einer Chemiefaserfirma wurden ein Jahr lang Experimente durchgeführt und dabei Betriebs-, Wetter- und Temperaturdaten aufgezeichnet. Die täglichen Wassertemperaturen, gemittelt über einen Monat, zeigten ausgezeichnete Übereinstimmung mit den theoretischen Vorausberechnungen und bestätigten so die Brauchbarkeit des vorgeschlagenen Wärmeübergangsmodells.

  14. Space transfer concepts and analyses for exploration missions. Technical directive 12: Beamed power systems study

    NASA Technical Reports Server (NTRS)

    Eder, D.

    1992-01-01

    Parametric models were constructed for Earth-based laser powered electric orbit transfer from low Earth orbit to geosynchronous orbit. These models were used to carry out performance, cost/benefit, and sensitivity analyses of laser-powered transfer systems including end-to-end life cycle cost analyses for complete systems. Comparisons with conventional orbit transfer systems were made indicating large potential cost savings for laser-powered transfer. Approximate optimization was done to determine best parameter values for the systems. Orbit transfer flights simulations were conducted to explore effects of parameters not practical to model with a spreadsheet. The simulations considered view factors that determine when power can be transferred from ground stations to an orbit transfer vehicle and conducted sensitivity analyses for numbers of ground stations, Isp including dual-Isp transfers, and plane change profiles. Optimal steering laws were used for simultaneous altitude and plane change. Viewing geometry and low-thrust orbit raising were simultaneously simulated. A very preliminary investigation of relay mirrors was made.

  15. Migrant Student Record Transfer System: What Is It and Who Uses It? ERIC Digest.

    ERIC Educational Resources Information Center

    Lunon, Janis K.

    Founded in 1969, the Migrant Student Record Transfer System (MSRTS) is a nationwide computerized information network which records, maintains, and rapidly transfers educational and health information on more than 750,000 identified migrant children in 29 states, the District of Columbia, and Puerto Rico. Based in Little Rock, Arkansas, the…

  16. Conjugated-polymer-based energy-transfer systems for antimicrobial and anticancer applications.

    PubMed

    Yuan, Huanxiang; Wang, Bing; Lv, Fengting; Liu, Libing; Wang, Shu

    2014-10-29

    Conjugated polymers (CPs) attract a lot of attention in sensing, imaging, and biomedical applications because of recent achievements that are highlighted in this Research News article. A brief review of recent progress in the application of CP-based energy-transfer systems in antimicrobial and anticancer treatments is provided. The transfer of excitation energy from CPs to photosensitizers leads to the generation of reactive oxygen species (ROS) that are able to efficiently kill pathogenic microorganisms and cancer cells in the surroundings. Both fluorescence resonance energy transfer (FRET) and bioluminescence energy transfer (BRET) modes are discussed. PMID:24711269

  17. Identification of boiler inlet transfer functions and estimation of system parameters

    NASA Technical Reports Server (NTRS)

    Miles, J. H.

    1972-01-01

    An iterative computer method is described for identifying boiler transfer functions using frequency response data. An objective penalized performance measure and a nonlinear minimization technique are used to cause the locus of points generated by a transfer function to resemble the locus of points obtained from frequency response measurements. Different transfer functions can be tried until a satisfactory empirical transfer function of the system is found. To illustrate the method, some examples and some results from a study of a set of data consisting of measurements of the inlet impedance of a single tube forced flow boiler with inserts are given.

  18. Risk factors for medication errors in the electronic and manual prescription 1

    PubMed Central

    Volpe, Cris Renata Grou; de Melo, Eveline Maria Magalhães; de Aguiar, Lucas Barbosa; Pinho, Diana Lúcia Moura; Stival, Marina Morato

    2016-01-01

    ABSTRACT Objective: to compare electronic and manual prescriptions of a public hospital of Brasilia, identifying risk factors for the occurrence of medication errors. Method: descriptive-exploratory, comparative and retrospective study. Data collection occurred from July 2012 to January 2013, using an instrument for the review of the information contained in medical records related to the medication process. A total of 190 manual and 199 electronic records composed the sample, with 2027 prescriptions each. Results: compared to the manual prescription, a significant reduction was observed in the risk factors after implantation of the electronic prescription, in items such as "lack of the form of dilution" (71.1% to 22.3%) and "prescription with brand name" (99.5% to 31.5%). Conversely, the risk factors "no check" and "lack of CRM of the prescriber" increased. The lack of the allergy registration and the occurrences related to medication were the same for both groups. Conclusion: generally, the use of the electronic prescription system was associated with a significant reduction in risk factors for medication errors, concerning the following aspects: illegibility, prescription with brand name and presence of essential items that provide a safe and effective prescription. PMID:27508913

  19. [Summary of Hui prescriptions for treating cough].

    PubMed

    Zhang, Wen-Jin; Xue, Ting; Fu, Xue-Yan; Zhang, Xin-Hui

    2015-01-01

    By using the method of philology, 65 Hui prescriptions for treating cough were been collected to compare Arabic and Chinese names of pennisetum, anemarrhenae, honey, pease, white mustard, perilla and towel gourd stem. The Countif function in Microsoft Excel 2007 was used to count frequency of drugs in the prescriptions and summarize eight common Hui medicine for treating cough, namely sugar, honey, almond, fritillaria, liquorice, orange peel, white mulberry root-bark and lily. According to the commonly used drugs, philological studies and theories of Hui medicines, pathology and therapy of Hui medicines for treating cough were preliminarily inferred. In this study, 35 practical prescriptions and 30 simple and convenient Halal dietary prescriptions were summarized from collected prescriptions according to relevant literatures. On the basis of the long-lasting unique dietary therapy culture developed for Hui people, the simple and practical dietary prescriptions were defined according indications, therapy, prescription name and composition, and eight types of drug-admixed foods were summarized to relieve pains and improve health awareness and quality of life. Meanwhile, this study could also enrich and perfect the prescriptions, provide new ideas for improving health of patients, and lay a certain realistic foundation for further study of Hui medicines. PMID:25993806

  20. 21 CFR 801.109 - Prescription devices.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Prescription devices. 801.109 Section 801.109 Food... DEVICES LABELING Exemptions From Adequate Directions for Use § 801.109 Prescription devices. A device... direct the use of such device, and hence for which “adequate directions for use” cannot be...

  1. 76 FR 51310 - Branded Prescription Drug Fee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-18

    ... Internal Revenue Service 26 CFR Part 51 RIN 1545-BJ39 Branded Prescription Drug Fee AGENCY: Internal... issuing temporary regulations relating to the branded prescription drug fee imposed by the Affordable Care... preliminary fee calculation is valid and justifies an adjustment to the preliminary fee calculation....

  2. Prescriptive Authority and Psychology: A Status Report

    ERIC Educational Resources Information Center

    Fox, Ronald E.; DeLeon, Patrick H.; Newman, Russ; Sammons, Morgan T.; Dunivin, Debra L.; Baker, Deborah C.

    2009-01-01

    The progress of psychology toward the acquisition of prescriptive authority is critically reviewed. Advances made by other nonphysician health care professions toward expanding their scopes of practice to include prescriptive authority are compared with gains made by professional psychology. Societal trends affecting attitudes toward the use of…

  3. Health Care Provider Physical Activity Prescription Intervention

    ERIC Educational Resources Information Center

    Josyula, Lakshmi; Lyle, Roseann

    2013-01-01

    Purpose: To examine the feasibility and impact of a health care provider’s (HCP) physical activity (PA) prescription on the PA of patients on preventive care visits. Methods: Consenting adult patients completed health and PA questionnaires and were sequentially assigned to intervention groups. HCPs prescribed PA using a written prescription only…

  4. A rigorous formalism of information transfer between dynamical system components. I. Discrete mapping

    NASA Astrophysics Data System (ADS)

    Liang, X. San; Kleeman, Richard

    2007-07-01

    We put the concept of information transfer on a rigorous footing and establish for it a formalism within the framework of discrete maps. The resulting transfer measure possesses a property of directionality or transfer asymmetry as emphasized by Schreiber [T. Schreiber, Measuring information transfer, Phys. Rev. Lett. 85 (2) (2000) 461]; it also verifies the transfer measure for two-dimensional systems, which was obtained by Liang and Kleeman [X.S. Liang, R. Kleeman, Information transfer between dynamical system components, Phys. Rev. Lett. 95 (24) (2005) 244101] through a different avenue. Connections to classical formalisms are explored and applications presented. We find that, in the context of the baker transformation, there is always information flowing from the stretching direction to the folding direction, while no transfer occurs in the opposite direction; we also find that, within the Hénon map system, the transfer from the quadratic component to the linear component is of a simple form as expected on physical grounds. This latter result is unique to our formalism.

  5. Code System to Predict LWR Reflood Heat Transfer.

    1999-04-27

    Version: 00 REFLUX calculates the temperature-time history of a representative fuel rod during the reflood stage of a hypothetical loss-of-coolant accident (LOCA). The logic used fo selection of the appropriate flow regime for analysis of the cladding temperature transient is based on the axial position with regard to the continuous liquid level (based on a mass balance), a liquid carry-over criterion (derived from a force balance on a drop suspended in a vapor stream), andmore » the local cladding surface temperature. A generalized boiling curve is constructed, and the local flow and clad conditions determine the applicable heat transfer coefficient.« less

  6. Bridge-mediated hopping or superexchange electron-transfer processes in bis(triarylamine) systems

    NASA Astrophysics Data System (ADS)

    Lambert, Christoph; Nöll, Gilbert; Schelter, Jürgen

    2002-09-01

    Hopping and superexchange are generally considered to be alternative electron-transfer mechanisms in molecular systems. In this work we used mixed-valence radical cations as model systems for the investigation of electron-transfer pathways. We show that substituents attached to a conjugated bridge connecting two triarylamine redox centres have a marked influence on the near-infrared absorption spectra of the corresponding cations. Spectral analysis, followed by evaluation of the electron-transfer parameters using the Generalized Mulliken-Hush theory and simulation of the potential energy surfaces, indicate that hopping and superexchange are not alternatives, but are both present in the radical cation with a dimethoxybenzene bridge. We found that the type of electron-transfer mechanism depends on the bridge-reorganization energy as well as on the bridge-state energy. Because superexchange and hopping follow different distance laws, our findings have implications for the design of new molecular and polymeric electron-transfer materials.

  7. [Pharmaceutical prescription in primary care. SESPAS report 2012].

    PubMed

    Sanfélix-Gimeno, Gabriel; Peiró, Salvador; Meneu, Ricard

    2012-03-01

    In 2010, the Spanish National Health Service (NHS) paid for 958 million prescriptions. Given the massive population exposure to medication, the risks associated with drug consumption are highly significant from the perspective of public health. Areas requiring improvement in primary care prescription include overtreatment of patients in low risk situations, undertreatment of those in whom medication is indicated, poor patient information, polymedication, self-medication and the appreciable percentage of preventable adverse effects. Surprisingly, most of the pharmaceutical strategies in the NHS have not aimed to address these problems but have instead concentrated on reducing pharmaceutical expenditure, which is not a problem of pharmaceutical expenditure per se but is rather a consequence of "the problems" of prescription (and of the regulation and management of pharmaceutical services). Some key elements to improve this situation include more integrated healthcare, the development of electronic medical records systems, overall strategies to improve safety, and reducing the role of the pharmaceutical industry. Macro strategies include creating an agency able to objectively assess the additional value provided by a new drug and its additional cost, price fixing in line with cost-effectiveness, and exclusion of drugs with little or no added value from coverage, etc. Managing prescription involves the development of longitudinal patient care programs that incorporate clinical actions from different professionals, including whom to treat, how much to treat and how to treat. PMID:22138282

  8. Horizontal gene transfer and mobile genetic elements in marine systems.

    PubMed

    Sobecky, Patricia A; Hazen, Tracy H

    2009-01-01

    The pool of mobile genetic elements (MGE) in microbial communities consists of viruses, plasmids, and associated elements (insertion sequences, transposons, and integrons) that are either self-transmissible or use mobile plasmids and viruses as vehicles for their dissemination. This mobilome facilitates the horizontal transfer of genes that promote the evolution and adaptation of microbial communities. Efforts to characterize MGEs from microbial populations resident in a variety of ecological habitats have revealed a surprisingly novel and seemingly untapped biodiversity. To better understand the impact of horizontal gene transfer (HGT), as well as the agents that promote HGT in marine ecosystems and to determine whether or not environmental parameters can effect the composition and structure of the mobilome in marine microbial communities, information on the distribution, diversity, and ecological traits of the marine mobilome is presented. In this chapter we discuss recent insights gained from different methodological approaches used to characterize the biodiversity and ecology of MGE in marine environments and their contributions to HGT. In addition, we present case studies that highlight specific HGT examples in coastal, open-ocean, and deep-sea marine ecosystems.

  9. Comparison of the transfer precision of three different impression materials in combination with transfer caps for the Frialit-2 system.

    PubMed

    Lorenzoni, M; Pertl, C; Penkner, K; Polansky, R; Sedaj, B; Wegscheider, W A

    2000-07-01

    Transfer of the precise position of implants to a master cast is a prerequisite for accurate and passive fit of the superstructure. Implants lack the mobility of natural teeth and, therefore, inaccurate frameworks result in stress within the mechanical parts and the implant-bone interface. Various impression methods have been described to achieve accurate reproduction of the intra-oral relation of the implants. The aim of this experimental study was to compare three different impression materials (polyether, polyvinyl siloxane, hydrocolloid) with the Frialit(R)-2 system and with the indirect technique. In addition, the use of transfer caps (TCs) to improve transfer precision was tested with all three materials. All measurements were performed using a three-dimensional (3D) co-ordinate measuring machine that is capable of locating points in space and calculating the relative distortions as angles of tilt (rot-XY, rot-XZ, rot-YZ) and 3D displacement. The results suggest that addition-silicone (a-silicone) and polyether are the materials of choice for implant transfer procedures. The use of TCs resulted in a significantly reduced rotation in the XY-plane but did not improve the absolute 3D displacement. A-silicone with the use of TCs proved to be most precise. Comparison between polyether and polyvinyl siloxane showed significant differences in the XY-rotation and the 3D displacement in favour of the silicone. Because the mean distortions between the original model and the master casts were about 100 microm, absolutely precise fit may be unattainable owing to the physical properties of the materials. Further studies will have to evaluate the amount of tolerable stress at the implant-bone interface. PMID:10931257

  10. Secular dynamics in hierarchical three-body systems with mass loss and mass transfer

    SciTech Connect

    Michaely, Erez; Perets, Hagai B.

    2014-10-20

    Recent studies have shown that secular evolution of triple systems can play a major role in the evolution and interaction of their inner binaries. Very few studies explored the stellar evolution of triple systems, and in particular the mass-loss phase of the evolving stellar components. Here we study the dynamical secular evolution of hierarchical triple systems undergoing mass loss. We use the secular evolution equations and include the effects of mass loss and mass transfer, as well as general relativistic effects. We present various evolutionary channels taking place in such evolving triples, and discuss both the effects of mass loss and mass transfer in the inner binary system, as well as the effects of mass loss/transfer from an outer third companion. We discuss several distinct types/regimes of triple secular evolution, where the specific behavior of a triple system can sensitively depend on its hierarchy and the relative importance of classical and general relativistic effects. We show that the orbital changes due to mass-loss and/or mass-transfer processes can effectively transfer a triple system from one dynamical regime to another. In particular, mass loss/transfer can both induce and quench high-amplitude (Lidov-Kozai) variations in the eccentricity and inclination of the inner binaries of evolving triples. They can also change the system dynamics from an orderly periodic behavior to a chaotic one, and vice versa.

  11. The mechanism of thermal-gradient mass transfer in the sodium hydroxide-nickel system

    NASA Technical Reports Server (NTRS)

    May, Charles E

    1958-01-01

    "Thermal-gradient mass transfer" was investigated in the molten sodium hydroxide-nickel system. Possible mechanisms (physical, electrochemical, and chemical) are discussed in terms of experimental and theoretical evidence. Experimental details are included in appendixes.

  12. Modulation transfer function of a digital dental x-ray system.

    PubMed

    Chen, S K; Hollender, L

    1994-03-01

    An impulse train method to control aliasing was used to measure the modulation transfer function of a digital dental x-ray system (RVG 32000 ZHR, Trophy Radiologie, Vincennes, France). The detector of this system is composed of an intensifying screen, a fiber optics taper, and a charged couple device chip. The modulation transfer function could not be measured by impulse method such as the line spread function or edge response function because of aliasing from undersampling of the digital system. The system modulation transfer function was difficult to recover at the spatial frequencies smaller than the Nyquist frequency. The modulation transfer function beyond the Nyquist frequencies was impossible to recover in this study.

  13. Simulation of a Wireless Power Transfer System for Electric Vehicles with Power Factor Correction

    SciTech Connect

    Pickelsimer, Michael C; Tolbert, Leon M; Ozpineci, Burak; Miller, John M

    2012-01-01

    Wireless power transfer has been a popular topic of recent research. Most research has been done to address the limitations of coil-to-coil efficiency. However, little has been done to address the problem associated with the low input power factor with which the systems operate. This paper details the steps taken to analyze a wireless power transfer system from the view of the power grid under a variety of loading conditions with and without power factor correction.

  14. Systems to Control Molten Metal Transfer in Arc Welding

    NASA Astrophysics Data System (ADS)

    Filonov, A. V.; Kryukov, A. V.; Gusarov, D. E.

    2015-09-01

    The paper analyzes the systems used for controlling molten wire metal droplets during the arc welding process in shielding gases. The variations for implementing the relevant systems are given, with the positive and negative aspects of such implementation taken into account. Electrical systems are currently investigated to the fullest extent possible and implemented in different power sources for pulsed welding arc. Mechanical systems are represented by different types of feeders that provide the pulsed wire feeding process. The feed mechanisms driven by electric motors and electromagnets are analyzed. In addition to the mechanical and electrical systems, the examples of combined control systems are given.

  15. Pythagorean coupling: Complete population transfer in a four-state system

    SciTech Connect

    Suchowski, Haim; Silberberg, Yaron; Uskov, Dmitry B.

    2011-07-15

    Complete population transfer in a four-coupled-modes system is analyzed from a geometrical point of view. An analytical solution of the dynamics is written by the use of two distinct frequencies, the generalization of the single Rabi frequency of the two-state dynamics. We also present its visualization on two separate Bloch spheres with two independent torque equations. With this scheme we analytically derive the requirements for complete population transfer in a four-state quantum system. Interestingly, the solutions are found to be linked to fundamental number theory, whereas complete population transfer occurs only if the ratios between coupling coefficients exactly match a set of Pythagorean triples.

  16. Vent System Analysis for the Cryogenic Propellant Storage Transfer Ground Test Article

    NASA Technical Reports Server (NTRS)

    Hedayat, A

    2013-01-01

    To test and validate key capabilities and technologies required for future exploration elements such as large cryogenic propulsion stages and propellant depots, NASA is leading the efforts to develop and design the Cryogenic Propellant Storage and Transfer (CPST) Cryogenic Fluid Management (CFM) payload. The primary objectives of CPST payload are to demonstrate: 1) in-space storage of cryogenic propellants for long duration applications; and 2) in-space transfer of cryogenic propellants. The Ground Test Article (GTA) is a technology development version of the CPST payload. The GTA consists of flight-sized and flight-like storage and transfer tanks, liquid acquisition devices, transfer, and pressurization systems with all of the CPST functionality. The GTA is designed to perform integrated passive and active thermal storage and transfer performance testing with liquid hydrogen (LH2) in a vacuum environment. The GTA storage tank is designed to store liquid hydrogen and the transfer tank is designed to be 5% of the storage tank volume. The LH2 transfer subsystem is designed to transfer propellant from one tank to the other utilizing pressure or a pump. The LH2 vent subsystem is designed to prevent over-pressurization of the storage and transfer tanks. An in-house general-purpose computer program was utilized to model and simulate the vent subsystem operation. The modeling, analysis, and the results will be presented in the final paper.

  17. 21 CFR 1306.21 - Requirement of prescription.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the pharmacy or pursuant to an oral prescription made by an individual practitioner and promptly... practitioner or the practitioner's agent to the pharmacy, an electronic prescription that meets...

  18. Heat-Transfer Fluids for Solar-Energy Systems

    NASA Technical Reports Server (NTRS)

    Parker, J. C.

    1982-01-01

    43-page report investigates noncorrosive heat-transport fluids compatible with both metallic and nonmetallic solar collectors and plumbing systems. Report includes tables and figures of X-ray inspections for corrosion and schematics of solar-heat transport systems and heat rejection systems.

  19. Dual manifold system and method for fluid transfer

    DOEpatents

    Doktycz, Mitchel J.; Bryan, William Louis; Kress, Reid

    2003-05-27

    A dual-manifold assembly is provided for the rapid, parallel transfer of liquid reagents from a microtiter plate to a solid state microelectronic device having biological sensors integrated thereon. The assembly includes aspiration and dispense manifolds connected by a plurality of conduits. In operation, the aspiration manifold is actuated such that the aspiration manifold is seated onto an array of reagent-filled wells of the microtiter plate. The wells are pressurized to force reagent through conduits toward the dispense manifold. A pressure pulse provided by a standard ink-jet printhead ejects nanoliter-to-picoliter droplets of reagent through an array of printhead orifices and onto test sites on the surface of the microelectronic device.

  20. Dual manifold system and method for fluid transfer

    DOEpatents

    Doktycz, Mitchel J.; Bryan, William Louis; Kress, Reid

    2003-09-30

    A dual-manifold assembly is provided for the rapid, parallel transfer of liquid reagents from a microtiter plate to a solid state microelectronic device having biological sensors integrated thereon. The assembly includes aspiration and dispense manifolds connected by a plurality of conduits. In operation, the aspiration manifold is actuated such that the aspiration manifold is seated onto an array of reagent-filled wells of the microtiter plate. The wells are pressurized to force reagent through conduits toward the dispense manifold. A pressure pulse provided by a standard ink-jet printhead ejects nanoliter-to-picoliter droplets of reagent through an array of printhead orifices and onto test sites on the surface of the microelectronic device.

  1. Code System to Calculate Heat and Mass Transfer In Concrete

    1999-05-26

    Version 00 This version is designated USINTC and was developed to model the thermal response of concrete to very high heating rates such as might occur from sodium spills on concrete surfaces in a breeder reactor. The major phenomena treated are conductive energy transport; chemical decomposition of concrete; and two-phase, three-component heat and mass transfer of the decomposition products: steam, liquid water, and carbon dioxide. The USINT model provides for porosity to increase as watermore » and carbon-dioxide are formed from the concrete. The concrete is treated generally as divided into two basic regions, wet and dry. In the wet region, steam, carbon-dioxide, and liquid water may co-exist, but in the dry region, there is no liquid water. There is also the possibility of a third region in which there is only liquid water and no gases.« less

  2. Heat transfer in space power and propulsion systems

    NASA Technical Reports Server (NTRS)

    Hendricks, R. C.; Simoneau, R. J.; Dunning, J. W., Jr.

    1986-01-01

    NASA's planned Space Station has projected power requirements in the 75-300 kW range; attention is presently given to the range of power system configurations thus far proposed. These are a silicon solar cell system incorporating regenerative fuel cell or battery storage, with a 10-year lifetime, a solar-dynamic power system with phase-change or regenerative fuel cell energy storage, and a combination of these two alternatives. A development status evaluation is also given for the propulsion systems that may be used by next-generation boosters. These include such novel airbreathing systems as turboramjets, air liquefaction cycle rockets, airturboramjet/rockets, and supersonic combustion ramjets.

  3. Real-time Prescription Surveillance and its Application to Monitoring Seasonal Influenza Activity in Japan

    PubMed Central

    Ohkusa, Yasushi; Ibuka, Yoko; Kawanohara, Hirokazu; Taniguchi, Kiyosu; Okabe, Nobuhiko

    2012-01-01

    Background Real-time surveillance is fundamental for effective control of disease outbreaks, but the official sentinel surveillance in Japan collects information related to disease activity only weekly and updates it with a 1-week time lag. Objective To report on a prescription surveillance system using electronic records related to prescription drugs that was started in 2008 in Japan, and to evaluate the surveillance system for monitoring influenza activity during the 2009–2010 and 2010–2011 influenza seasons. Methods We developed an automatic surveillance system using electronic records of prescription drug purchases collected from 5275 pharmacies through the application service provider’s medical claims service. We then applied the system to monitoring influenza activity during the 2009–2010 and 2010–2011 influenza seasons. The surveillance system collected information related to drugs and patients directly and automatically from the electronic prescription record system, and estimated the number of influenza cases based on the number of prescriptions of anti-influenza virus medication. Then it shared the information related to influenza activity through the Internet with the public on a daily basis. Results During the 2009–2010 influenza season, the number of influenza patients estimated by the prescription surveillance system between the 28th week of 2009 and the 12th week of 2010 was 9,234,289. In the 2010–2011 influenza season, the number of influenza patients between the 36th week of 2010 and the 12th week of 2011 was 7,153,437. The estimated number of influenza cases was highly correlated with that predicted by the official sentinel surveillance (r = .992, P < .001 for 2009–2010; r = .972, P < .001 for 2010–2011), indicating that the prescription surveillance system produced a good approximation of activity patterns. Conclusions Our prescription surveillance system presents great potential for monitoring influenza activity and for

  4. Impact of a Mandatory Prescription Drug Monitoring Program on Prescription of Opioid Analgesics by Dentists.

    PubMed

    Rasubala, Linda; Pernapati, Lavanya; Velasquez, Ximena; Burk, James; Ren, Yan-Fang

    2015-01-01

    Prescription Drug Monitoring Programs (PDMP) are statewide databases that collect data on prescription of controlled substances. New York State mandates prescribers to consult the PDMP registry before prescribing a controlled substance such as opioid analgesics. The effect of mandatory PDMP on opioid drug prescriptions by dentists is not known. This study investigates the impact of mandatory PDMP on frequency and quantity of opioid prescriptions by dentists in a dental urgent care center. Based on the sample size estimate, we collected patient records of a 3-month period before and two consecutive 3-month periods after the mandatory PDMP implementation and analyzed the data on number of visits, treatment types and drug prescriptions using Chi-square tests. For patients who were prescribed pain medications, 452 (30.6%), 190 (14.1%), and 140 (9.6%) received opioid analgesics in the three study periods respectively, signifying a statistically significant reduction in the number of opioid prescriptions after implementation of the mandatory PDMP (p<0.05). Total numbers of prescribed opioid pills in a 3-month period decreased from 5096 to 1120, signifying a 78% reduction in absolute quantity. Prescriptions for non-opioid analgesics acetaminophen increased during the same periods (p<0.05). We conclude that the mandatory PDMP significantly affected the prescription pattern for pain medications by dentists. Such change in prescription pattern represents a shift towards the evidence-based prescription practices for acute postoperative pain.

  5. Impact of a Mandatory Prescription Drug Monitoring Program on Prescription of Opioid Analgesics by Dentists.

    PubMed

    Rasubala, Linda; Pernapati, Lavanya; Velasquez, Ximena; Burk, James; Ren, Yan-Fang

    2015-01-01

    Prescription Drug Monitoring Programs (PDMP) are statewide databases that collect data on prescription of controlled substances. New York State mandates prescribers to consult the PDMP registry before prescribing a controlled substance such as opioid analgesics. The effect of mandatory PDMP on opioid drug prescriptions by dentists is not known. This study investigates the impact of mandatory PDMP on frequency and quantity of opioid prescriptions by dentists in a dental urgent care center. Based on the sample size estimate, we collected patient records of a 3-month period before and two consecutive 3-month periods after the mandatory PDMP implementation and analyzed the data on number of visits, treatment types and drug prescriptions using Chi-square tests. For patients who were prescribed pain medications, 452 (30.6%), 190 (14.1%), and 140 (9.6%) received opioid analgesics in the three study periods respectively, signifying a statistically significant reduction in the number of opioid prescriptions after implementation of the mandatory PDMP (p<0.05). Total numbers of prescribed opioid pills in a 3-month period decreased from 5096 to 1120, signifying a 78% reduction in absolute quantity. Prescriptions for non-opioid analgesics acetaminophen increased during the same periods (p<0.05). We conclude that the mandatory PDMP significantly affected the prescription pattern for pain medications by dentists. Such change in prescription pattern represents a shift towards the evidence-based prescription practices for acute postoperative pain. PMID:26274819

  6. Preoperational test report, cross-site transfer system integrated test (POTR-007)

    SciTech Connect

    Pacquet, E.A.

    1998-04-02

    This report documents the results obtained during the performance of Preoperational Test POTP-007, from December 12, 1997 to March 27, 1998. The main objectives were to demonstrate the operation of the following Cross-Site Transfer System components: Booster pumps P-3125A and P-3125B interlocks and controls, both local and remote; Booster pump P-3125A and P-3125B and associated variable speed drives VSD-1 and VSD-2 performance in both manual and automatic modes; and Water filling, circulation, venting and draining of the transfer headers (supernate and slurry line). As described in reference 1, the following components of the Cross-Site Transfer System that would normally be used during an actual waste transfer, are not used in this specific test: Water Flush System; Valving and instrumentation associated with the 241-SY-A valve pit jumpers; and Valving and instrumentation associated with the 244-A lift station.

  7. Hybrid quantum/classical approaches for proton transfer in condensed phase systems

    NASA Astrophysics Data System (ADS)

    Kim, Soo Young

    Nuclear quantum effects such as tunneling and zero point energy play an important role in proton transfer reactions. Since a fully quantum mechanical treatment of condensed phase systems is not practical, mixed quantum/classical methods have been developed to simulate proton transfer reactions in solution. In this work the molecular dynamics with quantum transitions (MDQT) method, which incorporates nonadiabatic transitions among the vibrational states, was extended to treat the donor-acceptor vibrational motion as well as the hydrogen motion quantum mechanically for proton transfer reactions. This approach was applied to a model system representing intramolecular proton transfer within a phenol-amine complex in liquid methyl chloride. In addition, a hybrid quantum/classical molecular dynamics approach was applied to a proton transfer reaction represented by a symmetric double well system coupled to a dissipative bath. The hybrid quantum/classical results agree well with numerically exact results in the spatial-diffusion-limited regime, which is most relevant for proton transfer in proteins. In these two studies, the fundamental issues such as the nuclear quantum effects of the proton and donor-acceptor motions and the dissipation effects in the hybrid quantum/classical approach were explored. These results have important implications for applications to hydrogen transfer reactions in solution and proteins.

  8. Time-resolved fluorescence study of electron transfer in a model peptide system

    NASA Astrophysics Data System (ADS)

    Donald, Fiona; Hungerford, Graham; Moore, Barry D.; Birch, David J. S.

    1994-08-01

    At present there is a great deal of interest in the study of the transference of energy in biological systems. For example, electron transfer is of major importance in many synthetic and biological processes and in nature is mediated by proteins. Information regarding this process is therefore useful in leading to a greater understanding of phenomena such as photosynthesis and respiration. Previous work on protein systems has shown the electron transfer process to be complex to analyze because of the presence of competing pathways. This has led to the use of model systems to simplify the kinetics. We have synthesized novel model systems using peptides containing both a fluorescent methoxy- naphthalene donor and a dicyanoethylene group as a potential electron acceptor and observed fluorescence quenching for both dipeptide and oligopeptide systems. Biexponential fluorescence decay behavior was observed for all donor acceptor systems, with an increase in the amount of the shorter fluorescence decay component on increasing temperature.

  9. Prescription drugs purchased through the internet: Who are the end users?

    PubMed Central

    Inciardi, James A.; Surratt, Hilary L.; Cicero, Theodore J.; Rosenblum, Andrew; Ahwah, Candice; Bailey, J. Elise; Dart, Richard C.; Burke, John J.

    2012-01-01

    Although prescription drugs are readily available on the Internet, little is known about the prevalence of Internet use for the purchase of medications without a legitimate prescription, and the characteristics of those that obtain non-prescribed drugs through online sources. The scientific literature on this topic is limited to anecdotal reports or studies plagued by small sample sizes. Within this context, the focus of this paper is an examination of five national data sets from the U.S. with the purpose of estimating: (1) how common obtaining prescription medications from the Internet actually is, (2) who are the typical populations of “end users” of these non-prescribed medications, and (3) which drugs are being purchased without a prescription. Three of the data sets are drawn from the RADARS® (Researched Abuse Diversion and Addiction-Related Surveillance) System, a comprehensive series of studies designed to collect timely and geographically specific data on the abuse and diversion of a number of prescription stimulants and opioid analgesics. The remaining data sets include the National Survey on Drug Use and Health (NSDUH) and the Monitoring the Future (MTF) survey. Our analysis yielded uniformly low rates of prescription drug acquisition from online sources across all five data systems we examined. The consistency of this finding across very diverse populations suggests that the Internet is a relatively minor source for illicit purchases of prescription medications by the individual end-users of these drugs. PMID:20227199

  10. 41 CFR 101-39.105-1 - Transfers from discontinued or curtailed fleet management systems.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... discontinued or curtailed fleet management systems. 101-39.105-1 Section 101-39.105-1 Public Contracts and... AVIATION, TRANSPORTATION, AND MOTOR VEHICLES 39-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.1-Establishment, Modification, and Discontinuance of Interagency Fleet Management Systems § 101-39.105-1 Transfers...

  11. Extension of service life of rigid transfer lines /SMDC/. [explosive components for aircraft escape systems

    NASA Technical Reports Server (NTRS)

    Bement, L. J.; Kayser, E. G.; Schimmel, M. L.

    1982-01-01

    The results of a life evaluation program on rigid explosive transfer lines, which are used to initiate aircraft emergency crew escape functions, are presented in order to provide quantitative information on rigid explosive transfer lines which can contribute to responsible, conservative, service life determinations. The program involved the development of a test methodology, testing of the three types of transfer lines in use in the U.S., testing of these lines following a repeat of the thermal test conducted in the original qualification, and conducting a degradation investigation. Results from the testing of more than 800 components showed that rigid explosive transfer lines were not affected by age, service, or a repeat of the thermal qualification tests on full-service lines. The explosive degradation limits were approximated and the mechanisms examined. It is concluded that the service lives of rigid explosive transfer lines should be considered for extension in order to provide cost savings and increased system reliability.

  12. One-two step transfer observed in 16O+11B nuclear system

    NASA Astrophysics Data System (ADS)

    Hamada, Sh.; Burtebayev, N.

    2015-06-01

    The angular distribution measurements for 16O ion beam elastically scattered from 11B target of thickness 32.9μg/cm2 at energy 22.4 MeV had been performed in the cyclotron DC-60 INP NNC RK. The previous measurements for 16O+11B nuclear system at energies 27, 30, 32.5 and 35 MeV showed an increase in the differential cross-section at backward angles due to the contribution of cluster transfer. Such transfer process could not be described in terms of optical model (OM); it could be described within the framework of distorted wave Born approximation method implemented in FRESCO code. Both one (5Li) and two-step transfer (proton transfer followed by Alpha transfer) were taken into considerations. We have extracted the spectroscopic amplitude (SA) for the configuration 16O→11B+5Li.

  13. Sequential energy and electron transfer in a three-component system aligned on a clay nanosheet.

    PubMed

    Fujimura, Takuya; Ramasamy, Elamparuthi; Ishida, Yohei; Shimada, Tetsuya; Takagi, Shinsuke; Ramamurthy, Vaidhyanathan

    2016-02-21

    To achieve the goal of energy transfer and subsequent electron transfer across three molecules, a phenomenon often utilized in artificial light harvesting systems, we have assembled a light absorber (that also serves as an energy donor), an energy acceptor (that also serves as an electron donor) and an electron acceptor on the surface of an anionic clay nanosheet. Since neutral organic molecules have no tendency to adsorb onto the anionic surface of clay, a positively charged water-soluble organic capsule was used to hold neutral light absorbers on the above surface. A three-component assembly was prepared by the co-adsorption of a cationic bipyridinium derivative, cationic zinc porphyrin and cationic octaamine encapsulated 2-acetylanthracene on an exfoliated anionic clay surface in water. Energy and electron transfer phenomena were monitored by steady state fluorescence and picosecond time resolved fluorescence decay. The excitation of 2-acetylanthracene in the three-component system resulted in energy transfer from 2-acetylanthracene to zinc porphyrin with 71% efficiency. Very little loss due to electron transfer from 2-acetylanthracene in the cavitand to the bipyridinium derivative was noticed. Energy transfer was followed by electron transfer from the zinc porphyrin to the cationic bipyridinium derivative with 81% efficiency. Analyses of fluorescence decay profiles confirmed the occurrence of energy transfer and subsequent electron transfer. Merging the concepts of supramolecular chemistry and surface chemistry we realized sequential energy and electron transfer between three hydrophobic molecules in water. Exfoliated transparent saponite clay served as a matrix to align the three photoactive molecules at a close distance in aqueous solutions. PMID:26820105

  14. An efficient wireless power transfer system with security considerations for electric vehicle applications

    SciTech Connect

    Zhang, Zhen; Chau, K. T. Liu, Chunhua; Qiu, Chun; Lin, Fei

    2014-05-07

    This paper presents a secure inductive wireless power transfer (WPT) system for electric vehicle (EV) applications, such as charging the electric devices inside EVs and performing energy exchange between EVs. The key is to employ chaos theory to encrypt the wirelessly transferred energy which can then be decrypted by specific receptors in the multi-objective system. In this paper, the principle of encrypted WPT is first revealed. Then, computer simulation is conducted to validate the feasibility of the proposed system. Moreover, by comparing the WPT systems with and without encryption, the proposed energy encryption scheme does not involve noticeable power consumption.

  15. Intense energy transfer and superharmonic resonance in a system of two coupled oscillators.

    PubMed

    Kovaleva, Agnessa; Manevitch, Leonid; Manevitch, Elina

    2010-05-01

    The paper presents the analytic study of energy exchange in a system of coupled nonlinear oscillators subject to superharmonic resonance. The attention is given to complete irreversible energy transfer that occurs in a system with definite initial conditions corresponding to a so-called limiting phase trajectory (LPT). We show that the energy imparted in the system is partitioned among the principal and superharmonic modes but energy exchange can be due to superharmonic oscillations. Using the LPT concept, we construct approximate analytic solutions describing intense irreversible energy transfer in a harmonically excited Duffing oscillator and a system of two nonlinearly coupled oscillators. Numerical simulations confirm the accuracy of the analytic approximations. PMID:20866315

  16. Preoperational test report, cross-site transfer water flush system (POTP-001)

    SciTech Connect

    Parsons, G.L.

    1998-02-20

    This report documents the results of the testing performed per POTP-001, for the Cross-Site Transfer Water Flush System. (HNF-1552, Rev. 0) The Flush System consists of a 47,000 gallon tank (302C), a 20 hp pump, two 498kW heaters, a caustic addition pump, various valves, instruments, and piping. The purpose of this system is to provide flush water at 140 F, 140gpm, and pH 11-12 for the Cross-Site Transfer System operation.

  17. Concepts to Automate Fluid Transfer Capability of Low Impact Docking System (LIDS)

    NASA Technical Reports Server (NTRS)

    Miernik, Janie H.; Lukens, Scott; Robertson, Jeff

    2005-01-01

    The capability to transfer mass between spacecraft is necessary for many mission scenarios. Docking and berthing operations have enabled fluid, electrical, crew and equipment transfers to some degree on all manned space operations since the Gemini program. The Apollo program performed some sophisticated docking maneuvers to land men on the moon and return them safely to Earth. These programs primarily transferred crew, equipment, and pressurized atmosphere between docked spacecraft. The International Space Station (ISS) U.S. modules are connected by Common Berthing Mechanism (CBM) portals. They provide many feed-through ports for electrical, and fluid transfer between modules, as well as a large diameter crew and equipment tunnel. Fluid and electrical jumpers are manually installed after the CBM sealing surfaces have been securely mated to maintain the pressurized cabin environment. CBM berthing and subsequent fluid transfer capability requires a lengthy manual process involving an active interface that mates with a passive half. The Androgynous Peripheral Attach System (MAS) a Russian technology that docked the Russian Zarya module to Unity, or Node 1, is a more complex system that also is capable of fuel transfer, enabling refueling of the Russian re-boost engines on ISS. For several years, a Low Impact Docking System (LIDS) has been under development at Johnson Space Center (JSC). This docking technology has a requirement to be androgynous in order to allow the fabrication of a single configuration that can dock with all other LIDS units. It is desired to make electrical and fluid coupling mating an automated process to enable routine docking and undocking operations to support future exploration missions. It is envisioned that modular design and vehicle assembly will require an efficient LIDS for fuel, electrical, crew, and equipment transfer. Marshall Space Flight Center (MSFC) has joined the LIDS development effort and plans to employ fluid transfer concepts

  18. Transfer function approach for artificial tracer test interpretation in karstic systems

    NASA Astrophysics Data System (ADS)

    Labat, D.; Mangin, A.

    2015-10-01

    A karstic formation consists in a three-dimensional hydrological system which involves horizontal and vertical, diphasic or saturated water transfers characterised by a large range of velocity. These subsurface flow processes correspond to various water pathways through fractured, fissured, and underground streams or conduits leading to a nonlinear global behaviour of the system. An efficient way of investigating of a karstic system behaviour consists in the injection of artificial tracer tests at loss points and in careful analysis of the recovery tracer fluxes at one or several outlets of the systems. These injections are also an efficient way of providing hypotheses on characteristic time of contaminant transfer in these type of aquifers. Here, we propose a Laplace-transform transfer function of the Residence Time Distribution function that allows to discriminate between a quick-flow advection-dominated component and a slow-flow advection-dispersion/dominated component in the artificial tracer transfer in the system. We apply this transfer function on five high resolution sampling rate artificial tracer tests operated on the Baget system in the Pyrenees (France) in order to illustrate the advantages and limitations of this approach. We provide then an interpretation of the relationship between tracer test recovery shape and karstic system organisation between inlet and outlet site.

  19. Photoinduced electron transfer and back transfer in systems of randomly distributed donors and acceptors: picosecond transient grating experiments

    SciTech Connect

    Dorfman, R.C.; Lin, Y.; Zimmt, M.B.; Baumann, J.; Domingue, R.P.; Fayer, M.D.

    1988-07-28

    Electron transfer from an optically excited donor (rubrene) to randomly distributed acceptors (duroquinone) followed by electron back transfer in a rigid solution (sucrose octaacetate) has been studied theoretically and experimentally. The forward electron transfer process was observed by time-dependent fluorescence quenching measurements, while the electron back transfer from the radical anion to the radical cation was monitored by using the picosecond transient grating (TG) technique. A statistical mechanics theory is used to describe the highly exponential TG signals and to extract the forward and back transfer parameters from the data. The agreement between the theory and experiments is excellent. The values of the forward and back transfer parameters are reported.

  20. Orbit transfer systems with emphasis on shuttle applications, 1986-1991

    NASA Technical Reports Server (NTRS)

    1977-01-01

    A systems study is presented for a transportation system which will follow the interim upper stage and spinning solid upper stage. Included are concepts, concept comparisons, trends, parametric data, etc. associated with the future system. Relevant technical and programmatic information is developed. This information is intended to focus future activity to identify attractive options and to summarize the major issues associated with the future development of the system. To establish a common basis for identifying current transportation concepts, an orbit transfer vehicle (OTV) is defined as a propulsive (velocity producing) rocket or stage. When used with a crew transfer module, a manned sortie module or other payloads, the combination becomes an orbit transfer system (OTS). Standardization of OTV's and OTS's is required.

  1. Cargo transfer vehicle - An element of the National Launch System

    NASA Technical Reports Server (NTRS)

    Buchanan, Harry

    1992-01-01

    The paper describes the cargo transport vehicle (CTV), a rendezvous- and capture-capable on-orbit maneuvering stage of the NASA/DOD National Launch System (NLS) developed for off-loading the Space Shuttle for cargo delivery to the Space Station Freedom. Special attention is given to the background of the NLS CTV technology, a typical Space Station delivery mission profile, the design features of the payload accommodation system, and the forward propulsion module. The feasibility of the CTV functioning as an upper stage, in addition to acting as an on-orbit maneuvering system, is being presently considered.

  2. Energy transfer in real and artificial photosynthetic systems

    SciTech Connect

    Hindman, J.C.; Hunt, J.E.; Katz, J.J.

    1995-02-01

    Fluorescence emission from the photosynthetic organisms Tribonema aequale, Anacystis nidulau, and Chlorelia vulgais and from some chlorophyll model systems have been recorded as a function of excitation wavelength and temperature. Considerable similarity was observed in the effects of excitation wavelength and temperature on the fluorescence from intact photosynthetic organisms and the model systems. The parallelism in behavior suggest that self-assembly processes may occur in both the in vivo and in vitro systems that give rise to chlorophyll species at low temperature that may differ significantly from those present at ambient temperatures.

  3. Comparison of two kinds of interface, based on guided navigation or usability principles, for improving the adoption of computerized decision support systems: application to the prescription of antibiotics

    PubMed Central

    Tsopra, Rosy; Jais, Jean-Philippe; Venot, Alain; Duclos, Catherine

    2014-01-01

    Context It is important to consider the way in which information is presented by the interfaces of clinical decision support systems, to favor the adoption of these systems by physicians. Interface design can focus on decision processes (guided navigation) or usability principles. Objective The aim of this study was to compare these two approaches in terms of perceived usability, accuracy rate, and confidence in the system. Materials and methods We displayed clinical practice guidelines for antibiotic treatment via two types of interface, which we compared in a crossover design. General practitioners were asked to provide responses for 10 clinical cases and the System Usability Scale (SUS) for each interface. We assessed SUS scores, the number of correct responses, and the confidence level for each interface. Results SUS score and percentage confidence were significantly higher for the interface designed according to usability principles (81 vs 51, p=0.00004, and 88.8% vs 80.7%, p=0.004). The percentage of correct responses was similar for the two interfaces. Discussion/conclusion The interface designed according to usability principles was perceived to be more usable and inspired greater confidence among physicians than the guided navigation interface. Consideration of usability principles in the construction of an interface—in particular ‘effective information presentation’, ‘consistency’, ‘efficient interactions’, ‘effective use of language’, and ‘minimizing cognitive load’—seemed to improve perceived usability and confidence in the system. PMID:24008427

  4. No Vent Tank Fill and Transfer Line Chilldown Analysis by Generalized Fluid System Simulation Program (GFSSP)

    NASA Technical Reports Server (NTRS)

    Majumdar, Alok

    2013-01-01

    The purpose of the paper is to present the analytical capability developed to model no vent chill and fill of cryogenic tank to support CPST (Cryogenic Propellant Storage and Transfer) program. Generalized Fluid System Simulation Program (GFSSP) was adapted to simulate charge-holdvent method of Tank Chilldown. GFSSP models were developed to simulate chilldown of LH2 tank in K-site Test Facility and numerical predictions were compared with test data. The report also describes the modeling technique of simulating the chilldown of a cryogenic transfer line and GFSSP models were developed to simulate the chilldown of a long transfer line and compared with test data.

  5. Immigration and the public transfer system: some empirical evidence for Switzerland.

    PubMed

    Weber, R; Straubhaar, T

    1996-01-01

    "Do immigrants subsidize the native population or vice versa? Is immigration a cost factor or a net benefit for the public transfer system? On the basis of the 1990 Swiss Consumer Survey, an attempt is made to answer these questions empirically.... The degree of participation of foreigners in the Swiss welfare state is estimated.... To this end, the public transfer balance (difference between government revenue and government expenditure) is empirically estimated for both native and foreign households. The method chosen covers public monetary transfers as well as the supply of goods and services by the government (real transfers). Social security insurance, redistribution through taxes, infrastructure investment (club goods) and immaterial goods such as the legal system (public goods) are thus covered." PMID:12292869

  6. CDC Vital Signs: Prescription Painkiller Overdoses

    MedlinePlus

    ... including screening and monitoring for substance abuse and mental health problems. Use prescription drug monitoring programs to identify ... effective pain treatment. Working to improve access to mental health and substance abuse treatment through implementation of the ...

  7. Closing the Prescription Drug Coverage Gap

    MedlinePlus

    ... name drugs when you buy them at a pharmacy or order them through the mail. • Some coverage ... savings if you buy your prescriptions at a pharmacy or order them through the mail. The discount ...

  8. Prescription Nonsteroidal Anti-Inflammatory Medicines

    MedlinePlus

    ... is called a drug-drug interaction. Vitamins and herbal supplements can affect the way your body processes drugs, ... over-the-counter and prescription medicines, vitamins and herbal supplements that you are taking. Also, talk to your ...

  9. Towards creating the perfect electronic prescription.

    PubMed

    Dhavle, Ajit A; Rupp, Michael T

    2015-04-01

    Significant strides have been made in electronic (e)-prescribing standards and software applications that have further fueled the adoption and use of e-prescribing. However, for e-prescribing to realize its full potential for improving the safety, effectiveness, and efficiency of prescription drug delivery, important work remains to be carried out. This perspective describes the ultimate goal of all e-prescribing stakeholders including prescribers and dispensing pharmacists: a clear, complete, and unambiguous e-prescription order that can be seamlessly received, processed, and fulfilled at the dispensing pharmacy without the need for additional clarification from the prescriber. We discuss the challenges to creating the perfect e-prescription by focusing on selected data segments and data fields that are available in the new e-prescription transaction as defined in the NCPDP SCRIPT Standard and suggest steps that could be taken to move the industry closer to achieving this vision. PMID:25038197

  10. Prescription Pain Medicines - An Addictive Path?

    MedlinePlus

    ... for addiction to these drugs, which include codeine, morphine, oxycodone (OxyContin), hydrocodone (Vicodin), and meperidine (Demerol). The ... the receptors in the brain affected by heroin, morphine, and prescription painkillers. The tablets relieve drug cravings ...

  11. The Conundrum of Online Prescription Drug Promotion

    PubMed Central

    Wanasika, Isaac

    2016-01-01

    This commentary discusses pertinent issues from Hyosun Kim’s paper on online prescription drug promotion. The study is well-designed and the findings highlight some of the consequences of the Food and Drug Administration’s (FDA’s) decision to deregulate online advertising of prescription drugs. While Kim’s findings confirm some of the early concerns, they also provide a perspective of implementation challenges in the ever-changing technological environment. PMID:27285519

  12. Safe exercise prescription for children and adolescents

    PubMed Central

    Alleyne, Julia MK

    1998-01-01

    This article provides practical advice on healthy exercise prescription for children. There is growing scientific evidence about the abilities and limits of child athletes in both recreational and competitive environments. As exercise becomes essential for the prevention of illness and maintenance of health, the counselling for an exercise prescription requires enhanced knowledge. The latest recommendations on safe strength, resistance and weight training are presented in a concise format for office use. PMID:20401276

  13. [FIRST CONSULTATION IN TEENAGERS FOR CONTRACEPTION PRESCRIPTION].

    PubMed

    Béliard, A

    2016-01-01

    Adequate contraception prescription is mandatory for teenagers to avoid any unwanted pregnancy. Counselling and description of side effect improve compliance. Use of condom is important to avoid sexually transmitted infections. Combined estroprogestin contraception has multiple non-contraceptive benefits, e.g. dysmenorrhea improvement. Familial and personal history is needed before contraception prescription. Further consultation 3 months later has to be planned to evaluate compliance, side effects and to adapt contraception if needed.

  14. Energy transfer enhancement by oxygen perturbation of spin-forbidden electronic transitions in aromatic systems

    NASA Astrophysics Data System (ADS)

    Monguzzi, A.; Tubino, R.; Salamone, M. M.; Meinardi, F.

    2010-09-01

    Triplet-triplet energy transfer in multicomponent organic systems is usually entirely ascribed to a Dexter-type mechanism involving only short-range donor/acceptor interactions. We demonstrate that the presence of molecular oxygen introduces a perturbation to the electronic structure of one of the involved moieties which can induce a large increase in the spin-forbidden transition oscillator strength so that the otherwise negligible Förster contribution dominates the overall energy transfer rate.

  15. 21 CFR 1306.12 - Refilling prescriptions; issuance of multiple prescriptions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... an individual practitioner acting in the usual course of professional practice; (ii) The individual... on which a pharmacy may fill each prescription; (iii) The individual practitioner concludes...

  16. Sneak circuit analysis of instrumentation and control systems. [technology transfer

    NASA Technical Reports Server (NTRS)

    Rankin, J. P.; Williams, A. M.

    1974-01-01

    The evolvement and implementation is presented of a systematic means for detecting the sneak prone designs of an electrical system which could result in such unplanned modes so that they can be prevented prior to occurrence. Sneak circuit analysis is shown to be a formalized approach based upon topological techniques. The trees employed are produced from manufacturing detail data processed by a computer to orderly completion. The analysis techniques applied on a variety of NASA programs are shown to be particularly applicable to industrial instrumentation and control systems.

  17. Augmentation of transfers for a quadriplegic patient using an implanted FNS system. Case report.

    PubMed

    Marsolais, E B; Scheiner, A; Miller, P C; Kobetic, R; Daly, J J

    1994-08-01

    A 22 year old man with incomplete quadriplegia (C6-7) was unable to perform either a sliding or a pivot transfer. He was instrumented with an implanted functional neuromuscular stimulation (FNS) system, radio frequency-linked to a belt-worn controller. The system activated eight muscles selected from among quadriceps, hamstrings, posterior portion of the adductor magnus, gluteus maximus, and erector spinae, bilaterally. The two-stage implantation procedure included electrode implantation with percutaneous leads followed by stimulator implantation and removal of the percutaneous leads. All implants were well tolerated with no adverse effects. The subject was able independently to put on the external controller portion of the system and to perform a standing pivot transfer with only standby assistance. An unexpected outcome of the FNS system use was increased voluntary upper body strength that resulted in improvement of the sliding transfer from 'inability' to 'independent'. PMID:7970864

  18. Testing of the West Valley Vitrification Facility transfer cart control system

    SciTech Connect

    Halliwell, J.W.; Bradley, E.C.

    1995-02-01

    Oak Ridge National Laboratory (ORNL) has designed and tested the control system for the West Valley Demonstration Project Vitrification Facility transfer cart. The transfer cart will transfer canisters of vitrified high-level waste remotely within the Vitrification Facility. The control system operates the cart under battery power by wireless control. The equipment includes cart-mounted control electronics, battery charger, control pendants, engineer`s console, and facility antennas. Testing was performed in several phases of development: (1) prototype equipment was built and tested during design, (2) board-level testing was then performed at ORNL during fabrication, and (3) system-level testing was then performed by ORNL at the fabrication subcontractor`s facility for the completed cart system. These tests verified (1) the performance of the cart relative to design requirements and (2) operation of various built-in cart features. The final phase of testing is planned to be conducted during installation at the West Valley Vitrification Facility.

  19. An impurity-induced gap system as a quantum data bus for quantum state transfer

    SciTech Connect

    Chen, Bing; Li, Yong; Song, Z.; Sun, C.-P.

    2014-09-15

    We introduce a tight-binding chain with a single impurity to act as a quantum data bus for perfect quantum state transfer. Our proposal is based on the weak coupling limit of the two outermost quantum dots to the data bus, which is a gapped system induced by the impurity. By connecting two quantum dots to two sites of the data bus, the system can accomplish a high-fidelity and long-distance quantum state transfer. Numerical simulations for finite system show that the numerical and analytical results of the effective coupling strength agree well with each other. Moreover, we study the robustness of this quantum communication protocol in the presence of disorder in the couplings between the nearest-neighbor quantum dots. We find that the gap of the system plays an important role in robust quantum state transfer.

  20. 21 CFR 1306.22 - Refilling of prescriptions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Refilling of prescriptions. 1306.22 Section 1306.22 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS Controlled Substances Listed in Schedules III, IV, and V § 1306.22 Refilling of prescriptions. (a) No prescription for a controlled substance listed in Schedule...

  1. 21 CFR 1306.05 - Manner of issuance of prescriptions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Manner of issuance of prescriptions. 1306.05 Section 1306.05 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS General Information § 1306.05 Manner of issuance of prescriptions. (a) All prescriptions for controlled substances shall be dated as of, and signed on,...

  2. 21 CFR 1306.22 - Refilling of prescriptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Refilling of prescriptions. 1306.22 Section 1306.22 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS Controlled... prescription it shall be deemed that the full face amount of the prescription has been dispensed....

  3. 21 CFR 1306.04 - Purpose of issue of prescription.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Purpose of issue of prescription. 1306.04 Section 1306.04 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS General Information § 1306.04 Purpose of issue of prescription. (a) A prescription for a controlled substance to...

  4. 21 CFR 1306.03 - Persons entitled to issue prescriptions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Persons entitled to issue prescriptions. 1306.03 Section 1306.03 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE PRESCRIPTIONS General Information § 1306.03 Persons entitled to issue prescriptions. (a) A prescription for a...

  5. Novel air-based system transfers large salmon during harvest

    Technology Transfer Automated Retrieval System (TEKTRAN)

    In April of 2015, near the end of our last harvest of 4-6 kg Atlantic salmon, we evaluated an exciting new fish transport technology from Whooshh Innovations (Bellevue, WA) that uses air to move live Atlantic salmon from our growout tank to a finishing/purging tank. The Whooshh system uses a combina...

  6. Radiative heat transfer in anisotropic many-body systems: Tuning and enhancement

    SciTech Connect

    Nikbakht, Moladad

    2014-09-07

    A general formalism for calculating the radiative heat transfer in many body systems with anisotropic component is presented. Our scheme extends the theory of radiative heat transfer in isotropic many body systems to anisotropic cases. In addition, the radiative heating of the particles by the thermal bath is taken into account in our formula. It is shown that the radiative heat exchange (HE) between anisotropic particles and their radiative cooling/heating (RCH) could be enhanced several order of magnitude than that of isotropic particles. Furthermore, we demonstrate that both the HE and RCH can be tuned dramatically by particles relative orientation in many body systems.

  7. Discrete time transfer matrix method for dynamics of multibody system with flexible beams moving in space

    NASA Astrophysics Data System (ADS)

    Rui, Xiao-Ting; Kreuzer, Edwin; Rong, Bao; He, Bin

    2012-04-01

    In this paper, by defining new state vectors and developing new transfer matrices of various elements moving in space, the discrete time transfer matrix method of multi-rigid-flexible-body system is expanded to study the dynamics of multibody system with flexible beams moving in space. Formulations and numerical example of a rigid-flexible-body three pendulums system moving in space are given to validate the method. Using the new method to study the dynamics of multi-rigid-flexible-body system moving in space, the global dynamics equations of system are not needed, the orders of involved matrices of the system are very low and the computational speed is high, irrespective of the size of the system. The new method is simple, straightforward, practical, and provides a powerful tool for multi-rigid-flexible-body system dynamics.

  8. 48 CFR 52.232-33 - Payment by Electronic Funds Transfer-System for Award Management.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Fedwire Transfer System. The rules governing Federal payments through the ACH are contained in 31 CFR part... contained in the System for Award Management (SAM) database. In the event that the EFT information changes, the Contractor shall be responsible for providing the updated information to the SAM database....

  9. Flow, aeration, and carbon dioxide transfer rates for airlifts used in recirculating aquaculture systems

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Airlift pumping systems reduce the electrical costs of moving water in a recirculating aquaculture system and can be concurrently designed to aerate water and remove carbon dioxide. This study determined the water flow, oxygen transfer, and CO2 removal rates for water using airlift technology in a 1...

  10. Technology transfer potential of an automated water monitoring system. [market research

    NASA Technical Reports Server (NTRS)

    Jamieson, W. M.; Hillman, M. E. D.; Eischen, M. A.; Stilwell, J. M.

    1976-01-01

    The nature and characteristics of the potential economic need (markets) for a highly integrated water quality monitoring system were investigated. The technological, institutional and marketing factors that would influence the transfer and adoption of an automated system were studied for application to public and private water supply, public and private wastewater treatment and environmental monitoring of rivers and lakes.

  11. Transfer of the EPA/NIH Chemical Information System (CIS) to Private Management.

    ERIC Educational Resources Information Center

    Kadec, Sarah T.; Jover, Antonio

    This paper discusses the programmatic concerns, the evaluation, and the ultimate decisions which led to the transfer of CIS (Chemical Information System) to the private sector. CIS is a complex, integrated system of some 20 chemical databases and data analysis programs which provide access to physical, toxicological, environmental effects, and…

  12. AW Ursae Majoris: a semidetached mass-transferring system indeed?

    NASA Astrophysics Data System (ADS)

    Eaton, Joel A.

    2016-03-01

    I have reinterpreted Rucinski's line profiles (broadening functions) for the hot A-type W Ursae Majoris binary AW UMa in terms of various contact models, finding that the detached/semidetached geometry he postulates does not fit the system's light variation or its line profiles. The highly overcontact geometry that actually fits the system's ellipsoidal light variation reproduce the total breadth of the lines but give profiles too broad to fit their shapes. The best solution to this dilemma is differential rotation of both stars in which the mid-latitudes are rotating 20-30 per cent slower than synchronously. This approach preserves the traditional light-curve solution and explains the drift of ripples seen in the line profiles. In addition, there are obviously other flows superimposed on the rotation which make the profiles asymmetrical. Fitting the line profiles is complicated by uncertainties in how the equivalent widths of the lines change with effective temperature and how much they are limb darkened. The contribution of any point on the stellar surface to the equivalent width depends only very weakly on local temperature throughout the range of W UMa binaries. The limb darkening of the lines is probably small, although the effect remains unexplored. I also speculate about the nature of hypothetical star-spots in this system.

  13. Remote Handled Transuranic Sludge Retrieval Transfer And Storage System At Hanford

    SciTech Connect

    Raymond, Rick E.; Frederickson, James R.; Criddle, James; Hamilton, Dennis; Johnson, Mike W.

    2012-10-18

    This paper describes the systems developed for processing and interim storage of the sludge managed as remote-handled transuranic (RH-TRU). An experienced, integrated CH2M HILL/AFS team was formed to design and build systems to retrieve, interim store, and treat for disposal the K West Basin sludge, namely the Sludge Treatment Project (STP). A system has been designed and is being constructed for retrieval and interim storage, namely the Engineered Container Retrieval, Transfer and Storage System (ECRTS).

  14. Validation of IEEE P1547.1 Interconnection Test Procedures: ASCO 7000 Soft Load Transfer System

    SciTech Connect

    Kroposki, B.; Englebretson, S.; Pink, C.; Daley, J.; Siciliano, R.; Hinton, D.

    2003-09-01

    This report presents the preliminary results of testing the ASCO 7000 Soft Load Transfer System according to IEEE P1547.1 procedures. The ASCO system interconnects synchronous generators with the electric power system and provides monitoring and control for the generator and grid connection through extensive protective functions. The purpose of this testing is to evaluate and give feedback on the contents of IEEE Draft Standard P1547.1 Conformance Tests Procedures for Equipment Interconnecting Distributed Resources With Electric Power Systems.

  15. A digital computer simulation and study of a direct-energy-transfer power-conditioning system

    NASA Technical Reports Server (NTRS)

    Burns, W. W., III; Owen, H. A., Jr.; Wilson, T. G.; Rodriguez, G. E.; Paulkovich, J.

    1974-01-01

    A digital computer simulation technique, which can be used to study such composite power-conditioning systems, was applied to a spacecraft direct-energy-transfer power-processing system. The results obtained duplicate actual system performance with considerable accuracy. The validity of the approach and its usefulness in studying various aspects of system performance such as steady-state characteristics and transient responses to severely varying operating conditions are demonstrated experimentally.

  16. D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis?

    PubMed

    Hammarström, Per; Sekijima, Yoshiki; White, Joleen T; Wiseman, R Luke; Lim, Amareth; Costello, Catherine E; Altland, Klaus; Garzuly, Ferenc; Budka, Herbert; Kelly, Jeffery W

    2003-06-10

    Over 70 transthyretin (TTR) mutations facilitate amyloidosis in tissues other than the central nervous system (CNS). In contrast, the D18G TTR mutation in individuals of Hungarian descent leads to CNS amyloidosis. D18G forms inclusion bodies in Escherichia coli, unlike the other disease-associated TTR variants overexpressed to date. Denaturation and reconstitution of D18G from inclusion bodies afford a folded monomer that is destabilized by 3.1 kcal/mol relative to an engineered monomeric version of WT TTR. Since TTR tetramer dissociation is typically rate limiting for amyloid formation, the monomeric nature of D18G renders its amyloid formation rate 1000-fold faster than WT. It is perplexing that D18G does not lead to severe early onset systemic amyloidosis, given that it is the most destabilized TTR variant characterized to date, more so than variants exhibiting onset in the second decade. Instead, CNS impairment is observed in the fifth decade as the sole pathological manifestation; however, benign systemic deposition is also observed. Analysis of heterozygote D18G patient's serum and cerebrospinal fluid (CSF) detects only WT TTR, indicating that D18G is either rapidly degraded postsecretion or degraded within the cell prior to secretion, consistent with its inability to form hybrid tetramers with WT TTR. The nondetectable levels of D18G TTR in human plasma explain the absence of an early onset systemic disease. CNS disease may result owing to the sensitivity of the CNS to lower levels of D18G aggregate. Alternatively, or in addition, we speculate that a fraction of D18G made by the choroid plexus can be transiently tetramerized by the locally high thyroxine (T(4)) concentration, chaperoning it out into the CSF where it undergoes dissociation and amyloidogenesis due to the low T(4) CSF concentration. Selected small molecule tetramer stabilizers can transform D18G from a monomeric aggregation-prone state to a nonamyloidogenic tetramer, which may prove to be a

  17. Computational modelling of placental amino acid transfer as an integrated system.

    PubMed

    Panitchob, N; Widdows, K L; Crocker, I P; Johnstone, E D; Please, C P; Sibley, C P; Glazier, J D; Lewis, R M; Sengers, B G

    2016-07-01

    Placental amino acid transfer is essential for fetal development and its impairment is associated with poor fetal growth. Amino acid transfer is mediated by a broad array of specific plasma membrane transporters with overlapping substrate specificity. However, it is not fully understood how these different transporters work together to mediate net flux across the placenta. Therefore the aim of this study was to develop a new computational model to describe how human placental amino acid transfer functions as an integrated system. Amino acid transfer from mother to fetus requires transport across the two plasma membranes of the placental syncytiotrophoblast, each of which contains a distinct complement of transporter proteins. A compartmental modelling approach was combined with a carrier based modelling framework to represent the kinetics of the individual accumulative, exchange and facilitative classes of transporters on each plasma membrane. The model successfully captured the principal features of transplacental transfer. Modelling results clearly demonstrate how modulating transporter activity and conditions such as phenylketonuria, can increase the transfer of certain groups of amino acids, but that this comes at the cost of decreasing the transfer of others, which has implications for developing clinical treatment options in the placenta and other transporting epithelia. PMID:27045077

  18. Quantifying information transfer and mediation along causal pathways in complex systems

    NASA Astrophysics Data System (ADS)

    Runge, Jakob

    2015-12-01

    Measures of information transfer have become a popular approach to analyze interactions in complex systems such as the Earth or the human brain from measured time series. Recent work has focused on causal definitions of information transfer aimed at decompositions of predictive information about a target variable, while excluding effects of common drivers and indirect influences. While common drivers clearly constitute a spurious causality, the aim of the present article is to develop measures quantifying different notions of the strength of information transfer along indirect causal paths, based on first reconstructing the multivariate causal network. Another class of novel measures quantifies to what extent different intermediate processes on causal paths contribute to an interaction mechanism to determine pathways of causal information transfer. The proposed framework complements predictive decomposition schemes by focusing more on the interaction mechanism between multiple processes. A rigorous mathematical framework allows for a clear information-theoretic interpretation that can also be related to the underlying dynamics as proven for certain classes of processes. Generally, however, estimates of information transfer remain hard to interpret for nonlinearly intertwined complex systems. But if experiments or mathematical models are not available, then measuring pathways of information transfer within the causal dependency structure allows at least for an abstraction of the dynamics. The measures are illustrated on a climatological example to disentangle pathways of atmospheric flow over Europe.

  19. Radiative transfer solutions for coupled atmosphere ocean systems using the matrix operator technique

    NASA Astrophysics Data System (ADS)

    Hollstein, André; Fischer, Jürgen

    2012-05-01

    Accurate radiative transfer models are the key tools for the understanding of radiative transfer processes in the atmosphere and ocean, and for the development of remote sensing algorithms. The widely used scalar approximation of radiative transfer can lead to errors in calculated top of atmosphere radiances. We show results with errors in the order of±8% for atmosphere ocean systems with case one waters. Variations in sea water salinity and temperature can lead to variations in the signal of similar magnitude. Therefore, we enhanced our scalar radiative transfer model MOMO, which is in use at Freie Universität Berlin, to treat these effects as accurately as possible. We describe our one-dimensional vector radiative transfer model for an atmosphere ocean system with a rough interface. We describe the matrix operator scheme and the bio-optical model for case one waters. We discuss some effects of neglecting polarization in radiative transfer calculations and effects of salinity changes for top of atmosphere radiances. Results are shown for the channels of the satellite instruments MERIS and OLCI from 412.5 nm to 900 nm.

  20. Selective coherence transfers in homonuclear dipolar coupled spin systems

    SciTech Connect

    Ramanathan, Chandrasekhar; Sinha, Suddhasattwa; Havel, Timothy F.; Cory, David G.; Baugh, Jonathan

    2005-02-01

    Controlling the dynamics of a dipolar coupled spin system is critical to the development of solid-state spin-based quantum information processors. Such control remains challenging, as every spin is coupled to a large number of surrounding spins. Here we demonstrate that in an ensemble of spin pairs it is possible to decouple the weaker interactions (weak coupling {omega}{sub D}{sup w}) between different pairs and extend the coherence lifetimes within the two-spin system from 19 {mu}s to 11.1 ms, a factor of 580. This is achieved without decoupling the stronger interaction (strong coupling {omega}{sub D}{sup S}) between the two spins within a pair. An amplitude modulated rf field is applied on resonance with the Larmor frequency of the spins, with amplitude {omega}{sub 1}, and frequency of the modulation matched to the strong coupling. The spin pairs appear isolated from each other in the regime where the rf power satisfies {omega}{sub D}{sup w}<<{omega}{sub 1}<<{omega}{sub D}{sup S}.

  1. Alternative generation and analysis for phase I privatization transfer system needs

    SciTech Connect

    Galbraith, J.D.

    1996-09-10

    This decision document provides input for the Phase I Privatization waste staging plans for the High-Level Waste (HLW)and Low-Level Waste (LLW) Disposal Programs. This AGA report evaluates what infrastructure upgrades to existing 200 East waste transfer systems are necessary for delivery of HLW and LLW streams to the Phase I Privatization vendor. The AGA identifies the transfer routing alternatives for supernatant waste transfers from the 241-AN, 241-AW, and 241-AP Tank Farms to the 241-AP-102 tank and/or the 241-AP-104 tank. These two tanks have been targeted as the initial LLW feed staging tanks. In addition,this report addresses the transfer of slurry waste from the 241-AY and 241-AZ Tank Farms to the Phase I Privatization vendor`s facilities for HLW immobilization.

  2. Chonopeltis australis (Crustacea) male reproductive system morphology; sperm transfer and review of reproduction in Branchiura.

    PubMed

    Neethling, Lourelle Alicia Martins; Avenant-Oldewage, Annemariè

    2015-02-01

    The morphology of the male reproductive system as well as sperm transfer in Branchiura has been described for Dolops ranarum and Argulus japonicus. In this study, the reproductive system and accessory structures are described for male Chonopeltis australis using histology, light microscopy, and scanning electron microscopy. For the first time, we describe sperm transfer by means of a spermatophore in this genus. The internal and external morphology and mechanism of sperm transfer is compared with other Branchiura, where it has been described. The morphology of the reproductive system of C. australis is similar to that of D. ranarum while the accessory structures and the spermatophore produced are similar to that of A. japonicus. A revision of the definition of Branchiura with respect to reproduction is provided.

  3. Heat transfer characteristics of current primary packaging systems for pharmaceutical freeze-drying.

    PubMed

    Hibler, Susanne; Gieseler, Henning

    2012-11-01

    In the field of freeze-drying, the primary packaging material plays an essential role. Here, the packaging system not only contains and protects the drug product during storage and shipping, but it is also directly involved in the freeze-drying process itself. The heat transfer characteristics of the actual container system influence product temperature and therefore product homogeneity and quality as well as process performance. Consequently, knowledge of the container heat transfer characteristics is of vital importance for process optimization. It is the objective of this review article to provide a summary of research focused on heat transfer characteristics of different container systems for pharmaceutical freeze-drying. Besides the common tubing and molded glass vials and metal trays, more recent packaging solutions like polymer vials, LYOGUARD® trays, syringes, and blister packs are discussed. Recent developments in vial manufacturing are also taken into account.

  4. Note: A simple sample transfer alignment for ultra-high vacuum systems

    NASA Astrophysics Data System (ADS)

    Tamtögl, A.; Carter, E. A.; Ward, D. J.; Avidor, N.; Kole, P. R.; Jardine, A. P.; Allison, W.

    2016-06-01

    The alignment of ultra-high-vacuum sample transfer systems can be problematic when there is no direct line of sight to assist the user. We present the design of a simple and cheap system which greatly simplifies the alignment of sample transfer devices. Our method is based on the adaptation of a commercial digital camera which provides live views from within the vacuum chamber. The images of the camera are further processed using an image recognition and processing code which determines any misalignments and reports them to the user. Installation has proven to be extremely useful in order to align the sample with respect to the transfer mechanism. Furthermore, the alignment software can be easily adapted for other systems.

  5. The measurement of water vapour transfer rate through clothing system with air gap between layers

    NASA Astrophysics Data System (ADS)

    Oh, Ae-Gyeong

    2008-02-01

    The experiments described in this paper are designed to test the water vapour transfer rates through outdoor clothing system with air gap between layers under conditions more closely actual wear. It was adopted distance of 5 mm to ensure no disturbance of the air gap thickness between layers throughout the measurement period with all fabrics. The results have indicated that the water vapour transfer rates of clothing system decrease very slightly with time, it is shown that they approached nearly equilibrium state throughout the experiment. It is revealed that the water vapour transfer rates of the clothing system were ordered into groups determined by the type of waterproof breathable fabric as a shell layer being ordered.

  6. Method of measuring heat influx of a cryogenic transfer system. [Patent application

    DOEpatents

    Niemann, R.C.; Zelipsky, S.A.; Rezmer, R.R.; Smelser, P.

    1980-10-29

    A method is provided for measuring the heat influx of a cryogenic transfer system. A gaseous phase of the cryogen used during normal operation of the system is passed through the system. The gaseous cryogen at the inlet to the system is tempered to duplicate the normal operating temperature of the system inlet. The temperature and mass flow rate of the gaseous cryogen is measured at the outlet of the system, and the heat capacity of the cryogen is determined. The heat influx of the system is then determined from known thermodynamic relationships.

  7. Molecular orbital assistance in the design of intramolecular and photoinduced electron transfer systems

    NASA Astrophysics Data System (ADS)

    Petsalakis, Ioannis D.; Theodorakopoulos, Giannoula

    2012-02-01

    A theoretical approach is described for the design of donor-acceptor intramolecular charge transfer (ICT) systems and for photoinduced electron transfer (PET) hybrids of fullerene, based on orbital level diagrams of the separate donor and acceptor moieties. Minimization of the HOMO-LUMO (highest occupied-lowest unoccupied orbital) gap in ICT systems, translates to a requirement for near degeneracy of the HOMO of the donor and LUMO of the acceptor, determined separately for the two moieties by density functional theory calculations. Similarly, near degeneracy of the LUMO of the donor and LUMO of the acceptor moieties would indicate the possibility of PET in the combined hybrid.

  8. Quantifying through-space charge transfer dynamics in π-coupled molecular systems

    NASA Astrophysics Data System (ADS)

    Batra, Arunabh; Kladnik, Gregor; Vázquez, Héctor; Meisner, Jeffrey S.; Floreano, Luca; Nuckolls, Colin; Cvetko, Dean; Morgante, Alberto; Venkataraman, Latha

    2012-09-01

    Understanding the role of intermolecular interaction on through-space charge transfer characteristics in π-stacked molecular systems is central to the rational design of electronic materials. However, a quantitative study of charge transfer in such systems is often difficult because of poor control over molecular morphology. Here we use the core-hole clock implementation of resonant photoemission spectroscopy to study the femtosecond charge-transfer dynamics in cyclophanes, which consist of two precisely stacked π-systems held together by aliphatic chains. We study two systems, [2,2]paracyclophane (22PCP) and [4,4]paracyclophane (44PCP), with inter-ring separations of 3.0 and 4.0 Å, respectively. We find that charge transfer across the π-coupled system of 44PCP is 20 times slower than in 22PCP. We attribute this difference to the decreased inter-ring electronic coupling in 44PCP. These measurements illustrate the use of core-hole clock spectroscopy as a general tool for quantifying through-space coupling in π-stacked systems.

  9. Radiative transfer in an atmosphere-ocean system.

    PubMed

    Plass, G N; Kattawar, G W

    1969-02-01

    The radiation field for an atmosphere-ocean system is calculated by a Monte Carlo method. In the atmosphere, both Rayleigh scattering by the molecules and Mie scattering by the aerosols and water droplets, when present, as well as molecular and aerosol absorption are included in the model. Similarly, in the ocean, both Rayleigh scattering by the water molecules and Mie scattering by the hydrosols as well as absorption by the water molecules and hydrosols are considered. Separate scattering functions are calculated from the Mie theory for the water droplets in clouds, the aerosols, and the hydrosols with an appropriate and different size distribution in each case. The photon path is followed accurately in three dimensions with new scattering angles determined from the appropriate scattering function including the strong forward scattering peak. Both the reflected and refracted rays, as well as the rays that undergo total internal reflection, are followed at the ocean surface, which is assumed smooth. The ocean floor is represented by a Lambert surface. The radiance and flux are given for two wavelengths, three solar angles, shallow and deep oceans, various albedos of ocean floor, various depths in atmosphere and ocean, and with and without clouds in the atmosphere.

  10. Type IV secretion: intercellular transfer of macromolecules by systems ancestrally related to conjugation machines.

    PubMed

    Christie, P J

    2001-04-01

    Bacterial conjugation systems are highly promiscuous macromolecular transfer systems that impact human health significantly. In clinical settings, conjugation is exceptionally problematic, leading to the rapid dissemination of antibiotic resistance genes and other virulence traits among bacterial populations. Recent work has shown that several pathogens of plants and mammals - Agrobacterium tumefaciens, Bordetella pertussis, Helicobacter pylori and Legionella pneumophila - have evolved secretion pathways ancestrally related to conjugation systems for the purpose of delivering effector molecules to eukaryotic target cells. Each of these systems exports distinct DNA or protein substrates to effect a myriad of changes in host cell physiology during infection. Collectively, secretion pathways ancestrally related to bacterial conjugation systems are now referred to as the type IV secretion family. The list of putative type IV family members is increasing rapidly, suggesting that macromolecular transfer by these systems is a widespread phenomenon in nature. PMID:11309113

  11. Gen Purpose 1-D Finite Element Network Fluid Flow Heat Transfer System Simulator

    1993-08-02

    SAFSIM (System Analysis Flow Simulator) is a FORTRAN computer program to simulate the integrated performance of systems involving fluid mechanics, heat transfer, and reactor dynamics. SAFSIM provides sufficient versatility to allow the engineering simulation of almost any system, from a backyard sprinkler system to a clustered nuclear reactor propulsion system. In addition to versatility, speed and robustness are primary SAFSIM development goals. SAFSIM contains three basic physics modules: (1) a one-dimensional finite element fluid mechanicsmore » module with multiple flow network capability; (2) a one-dimensional finite element structure heat transfer module with multiple convection and radiation exchange capability; and (3) a point reactor dynamics module with reactivity feedback and decay heat capability. SAFSIM can be used for compressible and incompressible, single-phase, multicomponent flow systems.« less

  12. Errors and omissions in hospital prescriptions: a survey of prescription writing in a hospital

    PubMed Central

    Calligaris, Laura; Panzera, Angela; Arnoldo, Luca; Londero, Carla; Quattrin, Rosanna; Troncon, Maria G; Brusaferro, Silvio

    2009-01-01

    Background The frequency of drug prescription errors is high. Excluding errors in decision making, the remaining are mainly due to order ambiguity, non standard nomenclature and writing illegibility. The aim of this study is to analyse, as a part of a continuous quality improvement program, the quality of prescriptions writing for antibiotics, in an Italian University Hospital as a risk factor for prescription errors. Methods The point prevalence survey, carried out in May 26–30 2008, involved 41 inpatient Units. Every parenteral or oral antibiotic prescription was analysed for legibility (generic or brand drug name, dose, frequency of administration) and completeness (generic or brand name, dose, frequency of administration, route of administration, date of prescription and signature of the prescriber). Eight doctors (residents in Hygiene and Preventive Medicine) and two pharmacists performed the survey by reviewing the clinical records of medical, surgical or intensive care section inpatients. The antibiotics drug category was chosen because its use is widespread in the setting considered. Results Out of 756 inpatients included in the study, 408 antibiotic prescriptions were found in 298 patients (mean prescriptions per patient 1.4; SD ± 0.6). Overall 92.7% (38/41) of the Units had at least one patient with antibiotic prescription. Legibility was in compliance with 78.9% of generic or brand names, 69.4% of doses, 80.1% of frequency of administration, whereas completeness was fulfilled for 95.6% of generic or brand names, 76.7% of doses, 83.6% of frequency of administration, 87% of routes of administration, 43.9% of dates of prescription and 33.3% of physician's signature. Overall 23.9% of prescriptions were illegible and 29.9% of prescriptions were incomplete. Legibility and completeness are higher in unusual drugs prescriptions. Conclusion The Intensive Care Section performed best as far as quality of prescription writing was concerned when compared with the

  13. Adiabatic population transfer in a three-level system driven by delayed laser pulses

    NASA Astrophysics Data System (ADS)

    Kuklinski, J. R.; Gaubatz, U.; Hioe, F. T.; Bergmann, K.

    1989-12-01

    We give a simple analytic solution that describes a novel method for population transfer in a three-level system driven by delayed pulses and which accounts for recent experimental results. This solution describes a procedure that is counterintuitive, and yet it is shown to be, in fact, one of the simplest solutions for multilevel systems arising from the adiabatic theorem. Its possible application to many-level systems is suggested.

  14. Volume of Courses Students Carry among Central Data Warehouse (CDW) Institutions: Implications for Recalibration of the BC Transfer System

    ERIC Educational Resources Information Center

    Box, Dale

    2008-01-01

    The British Columbia (BC) Council on Admissions and Transfer (BCCAT) has undertaken, in the last couple of years, a review of the BC Transfer System. Preliminary findings indicate that the current structure of the BC Transfer Guide (BCTG), which designates institutions as either "sending" institutions or "receiving" institutions, based upon their…

  15. Optimal control-based states transfer for non-Markovian quantum system

    NASA Astrophysics Data System (ADS)

    Ying-Hua, Ji; Ju-ju, Hu; Jian-Hua, Huang; Qiang, Ke

    2016-07-01

    Utilizing the method of optimal control, we investigate the tactics of state transfer in the non-Markovian quantum system with phase relaxation and energy dissipative relaxation. The influence of Ohmic reservoir with Lorentz-Drude regularization is numerically studied. Owing to the decoherence and memory effects of non-Markovian channel, the purity of quantum state attenuates damply in the free evolution. The numerical simulations indicate that arbitrary state transfer for non-Markovian system can be realized under the optimal control function by a proper external control field with a success rate of more than 98 percent. When the right control field and function is implemented, not only the decoherence is compensated completely but also the purity of quantum states are maintained in the process of state transfer.

  16. The New Transfer Line Collimation System for the LHC High Luminosity Era

    SciTech Connect

    Kain, Verena; Bracco, Chiara; Goddard, Brennan; Maciariello, Fausto; Meddahi, Malika; Mereghetti, Alessio; Steele, Genevieve; Velotti, Francesco; Gianfelice-Wendt, Eliana

    2014-07-01

    A set of passive absorbers is located at the end of each of the 3 km long injection lines to protect the LHC in case of failures during the extraction process from the LHC’s last pre-injector or the beam transfer itself. In case of an erroneous extraction, the absorbers have to attenuate the beam to a safe level and be robust enough themselves to survive the impact. These requirements are difficult to fulfil with the very bright and intense beams produced by the LHC injectors for the high luminosity era. This paper revisits the requirements for the SPS-to-LHC transfer line collimation system and the adapted strategy to fulfill these for the LHC high luminosity operation. A possible solution for the new transfer line collimation system is presented.

  17. State prescription drug price Web sites: how useful to consumers?

    PubMed

    Tu, Ha T; Corey, Catherine G

    2008-02-01

    To aid consumers in comparing prescription drug costs, many states have launched Web sites to publish drug prices offered by local retail pharmacies. The current push to make retail pharmacy prices accessible to consumers is part of a much broader movement to increase price transparency throughout the health-care sector. Efforts to encourage price-based shopping for hospital and physician services have encountered widespread concerns, both on grounds that prices for complex services are difficult to measure and compare accurately and that quality varies substantially across providers. Experts agree, however, that prescription drugs are much easier to shop for than other, more complex health services. However, extensive gaps in available price information--the result of relying on Medicaid data--seriously hamper the effectiveness of state drug price-comparison Web sites, according to a new study by the Center for Studying Health System Change (HSC). An alternative approach--requiring pharmacies to submit price lists to the states--would improve the usefulness of price information, but pharmacies typically oppose such a mandate. Another limitation of most state Web sites is that price information is restricted to local pharmacies, when online pharmacies, both U.S. and foreign, often sell prescription drugs at substantially lower prices. To further enhance consumer shopping tools, states might consider expanding the types of information provided, including online pharmacy comparison tools, lists of deeply discounted generic drugs offered by discount retailers, and lists of local pharmacies offering price matches. PMID:18494180

  18. Determinants of branded prescription medicine prices in OECD countries.

    PubMed

    Kanavos, Panos G; Vandoros, Sotiris

    2011-07-01

    This paper investigates the determinants of the prices of branded prescription medicines across different regulatory settings and health care systems, taking into account their launch date, patent status, market dynamics and the regulatory context in which they diffuse. By using volume-weighted price indices, this paper analyzes price levels for a basket of prescription medicines and their differences in 15 OECD countries, including the United States and key European countries, the impact of distribution margins and generic entry on public prices and to what extent innovation, by means of introducing newer classes of medicines, contributes to price formation across countries. In doing so, the paper seeks to understand the factors that contribute to the existing differences in prices across countries, whether at an ex-factory or a retail level. The evidence shows that retail prices for branded prescription medicines in the United States are higher than those in key European and other OECD countries, but not as high as widely thought. Large differences in prices are mainly observed at an ex-factory level, but these are not the prices that consumers and payers pay. Cross-country differences in retail prices are actually not as high as expected and, when controlling for exchange rates, these differences can be even smaller. Product age has a significant effect on prices in all settings after having controlled for other factors. Price convergence is observed across countries for newer prescription medicines compared with older medicines. There is no evidence that originator brand prices fall after generic entry in the United States, a phenomenon known as the 'generics paradox'. Finally, distribution and taxes are important determinants of retail prices in several of the study countries. To the extent that remuneration of the distribution chain and taxation are directly and proportionately linked to product prices this is likely to persist over time.

  19. Validity of the Prescriber Information in the Danish National Prescription Registry.

    PubMed

    Rasmussen, Lotte; Valentin, Julie; Gesser, Katarina Margareta; Hallas, Jesper; Pottegård, Anton

    2016-10-01

    The aim of this study was to measure the validity of the prescriber information recorded in the Danish National Prescription Registry (DNPR). The prescriber information recorded in the pharmacies' electronic dispensing system was considered to represent the prescriber information recorded in the DNPR. Further, the problem of validity of the prescriber information pertains only to non-electronic prescriptions, as these are manually entered into the dispensing system. The recorded prescriber information was thus validated against information from a total of 2000 non-electronic prescriptions at five Danish community pharmacies. The validity of the recorded prescriber information was measured at the level of the individual prescriber and the prescriber type, respectively. The proportion of non-electronic prescriptions with incorrect registrations was 22.4% (95% confidence interval (CI): 20.6-24.3) when considering individual prescriber identifiers and 17.8% (95% CI: 16.1-19.5) when considering prescriber type. When excluding prescriptions specifically registered as 'missing prescriber identifier', the proportions decreased to 9.5% (95% CI: 8.2-11.0) and 4.1% (95% CI: 3.2-5.1), respectively. The positive predictive values for the classification of prescriber types were in the range of 94.0-99.2%, while the sensitivity ranged between 64.6% and 91.8%. With a maximum of 14% non-electronic prescriptions of all prescriptions in the DNPR in 2015, this corresponds to correct classification of prescriber types in the DNPR of at least 97.5%. In conclusion, the prescriber information in the DNPR was found to be valid, especially in recent years. Researchers should be aware of the low sensitivity towards prescriptions from private practicing specialists.

  20. Is 50 cent the price of the optimal copayment? - a qualitative study of patient opinions and attitudes in response to a 50 cent charge on prescription drugs in a publicly funded health system in Ireland

    PubMed Central

    2013-01-01

    Background A 50 cent prescription levy was introduced in 2010 on the General Medical Services (GMS) scheme (Irish public health insurance). This study sought to examine patient attitudes and opinions surrounding the 50 cent copayment. Given the small momentary value of the prescription fee, these results are of interest to policymakers internationally who wish to reduce copayments rather than abolish them. Methods A qualitative research design was used; semi structured interviews were carried out. Twenty four GMS eligible participants were interviewed in 23 interviews. Fifteen females and 9 males took part. Ages varied from 31- >70 years. Patients were invited to be interviewed in both independent and chain community pharmacies in three types of setting; 1) a socially deprived urban area, 2) a suburban affluent area and 3) a rural area. The Framework method was used for data management and analysis using QSR International’s NVivo 9.2 qualitative data analysis software. The “Francis method” was used to test for data saturation. Results Results are of interest to the Irish context and also at a broader international level. Patients were mostly accepting of the prescription levy with some reservations concerning an increased price and the way in which generated revenue would be used by government. Participants identified waste of prescription drugs at the hand of patients (moral hazard), but there was discordant opinion on whether the 50 cent copayment would halt this moral hazard. Interviewees felt the levy was affordable, albeit some may suffer a financial impact more than others. Conclusions This qualitative study gives important insights into the experiences of GMS patients with regard to the prescription levy. Information regarding the appropriateness of a 50 cent copayment as a symbolic copayment needs to be confirmed by quantitative analysis. Further insight is required from a younger population. PMID:23305316

  1. The effect of the liquid-solid system properties on the interline heat transfer coefficient

    NASA Technical Reports Server (NTRS)

    Wayner, P. C., Jr.

    1977-01-01

    A theoretical procedure to determine the heat transfer characteristics of the interline region of an evaporating meniscus using the macroscopic optical and thermophysical properties of the system is outlined. The analysis is based on the premise that the interline transport processes are controlled by the London-van der Waals forces between condensed phases (solid and liquid). The procedure is used to compare the relative size of the interline heat sink of various systems using a constant heat flux model. This solution demonstrates the importance of the interline heat flow number which is evaluated for various systems. The heat transfer characteristics of the decane-steel system are numerically compared with those of the carbon tetrachloride-quartz system.

  2. Prescription Patterns of General Practitioners in Peshawar, Pakistan

    PubMed Central

    Raza, Usman Ahmad; Khursheed, Tayyeba; Irfan, Muhammad; Abbas, Maryam; Irfan, Uma Maheswari

    2014-01-01

    Objectives: To find out prescription patterns of general practitioners in Peshawar. Methods: Cross-sectional survey of drug prescriptions was done at six major hospitals and pharmacies of Peshawar between April and May 2011. A total of 1097 prescriptions that included 3640 drugs, were analyzed to assess completeness, average number of drugs, prescription frequency of various drug classes, and number of brands prescribed. Results: No prescription contained all essential components of a prescription. Legibility was poor in 58.5% prescriptions. Physician’s name and registration number were not mentioned in 89% and 98.2% prescriptions respectively. Over 78% prescriptions did not have diagnosis or indication mentioned. Dosage, duration of use, signature of physician and directions for taking drugs were not written in 63.8%, 55.4%, 18.5% and 10.9% of prescriptions respectively. On average each prescription included 3.32 drugs. Most frequently prescribed drug classes included analgesics (61.7%), anti-infective agents (57.2%), multi-vitamins (37.8%) and gastrointestinal drugs (34.4%). We found 206, 130, 105 and 101 different brands of anti-infective agents, gastrointestinal drugs, analgesics and multivitamins being prescribed. Conclusion: We observed a high number of average drugs per prescription mostly using brand names, and over-prescription of analgesics, antimicrobials, multivitamins and anti-ulcer drugs. Quality of written prescriptions was poor in terms of completeness. PMID:24948959

  3. Laboratory transferability of optimally shaped laser pulses for quantum control.

    PubMed

    Moore Tibbetts, Katharine; Xing, Xi; Rabitz, Herschel

    2014-02-21

    Optimal control experiments can readily identify effective shaped laser pulses, or "photonic reagents," that achieve a wide variety of objectives. An important additional practical desire is for photonic reagent prescriptions to produce good, if not optimal, objective yields when transferred to a different system or laboratory. Building on general experience in chemistry, the hope is that transferred photonic reagent prescriptions may remain functional even though all features of a shaped pulse profile at the sample typically cannot be reproduced exactly. As a specific example, we assess the potential for transferring optimal photonic reagents for the objective of optimizing a ratio of photoproduct ions from a family of halomethanes through three related experiments. First, applying the same set of photonic reagents with systematically varying second- and third-order chirp on both laser systems generated similar shapes of the associated control landscape (i.e., relation between the objective yield and the variables describing the photonic reagents). Second, optimal photonic reagents obtained from the first laser system were found to still produce near optimal yields on the second laser system. Third, transferring a collection of photonic reagents optimized on the first laser system to the second laser system reproduced systematic trends in photoproduct yields upon interaction with the homologous chemical family. These three transfers of photonic reagents are demonstrated to be successful upon paying reasonable attention to overall laser system characteristics. The ability to transfer photonic reagents from one laser system to another is analogous to well-established utilitarian operating procedures with traditional chemical reagents. The practical implications of the present results for experimental quantum control are discussed. PMID:24559348

  4. Laboratory transferability of optimally shaped laser pulses for quantum control

    NASA Astrophysics Data System (ADS)

    Moore Tibbetts, Katharine; Xing, Xi; Rabitz, Herschel

    2014-02-01

    Optimal control experiments can readily identify effective shaped laser pulses, or "photonic reagents," that achieve a wide variety of objectives. An important additional practical desire is for photonic reagent prescriptions to produce good, if not optimal, objective yields when transferred to a different system or laboratory. Building on general experience in chemistry, the hope is that transferred photonic reagent prescriptions may remain functional even though all features of a shaped pulse profile at the sample typically cannot be reproduced exactly. As a specific example, we assess the potential for transferring optimal photonic reagents for the objective of optimizing a ratio of photoproduct ions from a family of halomethanes through three related experiments. First, applying the same set of photonic reagents with systematically varying second- and third-order chirp on both laser systems generated similar shapes of the associated control landscape (i.e., relation between the objective yield and the variables describing the photonic reagents). Second, optimal photonic reagents obtained from the first laser system were found to still produce near optimal yields on the second laser system. Third, transferring a collection of photonic reagents optimized on the first laser system to the second laser system reproduced systematic trends in photoproduct yields upon interaction with the homologous chemical family. These three transfers of photonic reagents are demonstrated to be successful upon paying reasonable attention to overall laser system characteristics. The ability to transfer photonic reagents from one laser system to another is analogous to well-established utilitarian operating procedures with traditional chemical reagents. The practical implications of the present results for experimental quantum control are discussed.

  5. An integrated orthognathic surgery system for virtual planning and image-guided transfer without intermediate splint.

    PubMed

    Kim, Dae-Seung; Woo, Sang-Yoon; Yang, Hoon Joo; Huh, Kyung-Hoe; Lee, Sam-Sun; Heo, Min-Suk; Choi, Soon-Chul; Hwang, Soon Jung; Yi, Won-Jin

    2014-12-01

    Accurate surgical planning and transfer of the planning in orthognathic surgery are very important in achieving a successful surgical outcome with appropriate improvement. Conventionally, the paper surgery is performed based on a 2D cephalometric radiograph, and the results are expressed using cast models and an articulator. We developed an integrated orthognathic surgery system with 3D virtual planning and image-guided transfer. The maxillary surgery of orthognathic patients was planned virtually, and the planning results were transferred to the cast model by image guidance. During virtual planning, the displacement of the reference points was confirmed by the displacement from conventional paper surgery at each procedure. The results of virtual surgery were transferred to the physical cast models directly through image guidance. The root mean square (RMS) difference between virtual surgery and conventional model surgery was 0.75 ± 0.51 mm for 12 patients. The RMS difference between virtual surgery and image-guidance results was 0.78 ± 0.52 mm, which showed no significant difference from the difference of conventional model surgery. The image-guided orthognathic surgery system integrated with virtual planning will replace physical model surgical planning and enable transfer of the virtual planning directly without the need for an intermediate splint.

  6. Effects of cooling system parameters on heat transfer in PAFC stack. Ph.D. Thesis

    NASA Technical Reports Server (NTRS)

    Abdul-Aziz, Ali A.

    1985-01-01

    Analytical and experimental study for the effects of cooling system parameters on the heat transfer and temperature distribution in the electrode plates of a phosphoric acid fuel-cell has been conducted. An experimental set-up that simulates the operating conditions prevailing in a phosphoric-acid fuel-cell stack was designed and constructed. The set-up was then used to measure the overall heat transfer coefficient, the thermal contact resistance, and the electrode temperature distribution for two different cooling plate configurations. Two types of cooling plate configurations, serpentine and straight, were tested. Air, water, and oil were used as coolants. Measurements for the heat transfer coefficient and the thermal contact resistance were made for various flow rates ranging from 16 to 88 Kg/hr, and stack clamping pressure ranging from O to 3448 Kpa. The experimental results for the overall heat transfer coefficient were utilized to derive mathematical relations for the overall heat transfer coefficient as a function of stack clamping pressure and Reynolds number for the three coolants. The empirically derived formulas were incorporated in a previously developed computer program to predict electrodes temperature distribution and the performance of the stack cooling system. The results obtained were then compared with those available in the literature. The comparison showed maximum deviation of +/- 11%.

  7. Entanglement transfer from two-mode anti-correlated continuous-variable systems to a pair of localized discrete systems

    NASA Astrophysics Data System (ADS)

    Ran, Du; Yang, Zhen-Biao

    2016-04-01

    We address the entanglement transfer from a bipartite continuous-variable(CV) system to a pair of localized discrete systems. The dynamics behavior can be implemented by two two-level atoms flying through spatially separated identical cavities where two quantized modes are injected. We assume each CV mode couples to one atom via the resonant Jaynes-Cummings interaction. The CV systems are initially prepared in a two-mode anti-correlated SU(2) coherent state, while with the initial atomic states of the cases: |g⟩1|g⟩2, |e⟩1|e⟩2 and |g⟩1|e⟩2, respectively. We find that the entanglement transfer for single-photon excitation case is more efficient than that for multi-photon excitation case. Under same conditions, we also note that the entanglement transfer is more efficient for SU(2) coherent state than for twin-bean (TWB) and pair-coherent (TMC) state. Besides, we show that, for a given total photon number of the initial SU(2) coherent state, the efficiency of entanglement transfer depends upon the distribution of photons in the two CV modes. We also consider the influences of the dissipation and the white noise on the entanglement transfer.

  8. Heat Transfer Analysis of an Engine Exhaust-Based Thermoelectric Evaporation System

    NASA Astrophysics Data System (ADS)

    Chen, Ming; Tan, Gangfeng; Guo, Xuexun; Deng, Yadong; Zhang, Hongguang; Yang, Kai

    2016-03-01

    Engine exhaust can be used by thermoelectric generators for improving thermal efficiency of internal combustion engines. In his paper, the performance of a thermoelectric evaporation system is investigated. First, the thermal characteristics of diesel engines are obtained according to the experiment data. Then, mathematical models are created based on the specified conditions of the coolant cycle and the evaporator geometric parameters. Finally, the heat transfer characteristics and power performance of the thermoelectric evaporation system are estimated, and a comparison with the system in which the heat exchanger operates with all-liquid coolant is investigated. The results show that the overall heat transfer rate of the thermoelectric evaporator system increases with engine power. At the rated condition, the two-phase zone with an area of 0.8689 m2 dominates the evaporator's heat transfer area compared with the preheated zone area of 0.0055 m2, and for the thermoelectric module, the cold-side temperature is stable at 74°C while the hot-side temperature drops from 341.8°C to 304.9°C along the exhaust direction. For certain thermoelectric cells, the temperature difference between the cold side and hot side rises with the engine load, and the temperature difference drops from 266.9°C to 230.6°C along the exhaust direction. For two cold-side systems with the same heat transfer, coolant mass flow rate in the evaporator with two-phase state is much less, and the temperature difference along with equivalent heat transfer length L is significantly larger than in the all-liquid one. At rated power point, power generated by thermoelectric cells in the two-phase evaporation system is 508.4 W, while the other is only 328.8 W.

  9. A STRUCTURAL INTEGRITY EVALUATION OF THE TANK FARM WASTE TRANSFER SYSTEM

    SciTech Connect

    Wiersma, B.

    2006-03-09

    Radioactive supernate, salt, and/or sludge wastes (i.e., high level wastes) are confined in 49 underground storage tanks at the Savannah River Site (SRS). The waste is transported between tanks within and between the F and H area tank farms and other facilities on site via underground and a limited number of aboveground transfer lines. The Department of Energy - Savannah River Operations Office (DOE-SR) performed a comprehensive assessment of the structural integrity program for the Tank Farm waste transfer system at the SRS. This document addresses the following issues raised during the DOE assessment: (1) Inspections of failed or replaced transfer lines indicated that the wall thickness of some core and jacket piping is less than nominal; (2) No corrosion allowance is utilized in the transfer line structural qualification calculations. No basis for neglecting corrosion was provided in the calculations; (3) Wall loss due to erosion is not addressed in the transfer line structural qualification calculations; and (4) No basis is provided for neglecting intergranular stress corrosion cracking in the transfer line structural qualification calculations. The common theme in most of these issues is the need to assess the potential for occurrence of material degradation of the transfer line piping. The approach used to resolve these issues involved: (1) Review the design and specifications utilized to construct and fabricate the piping system; (2) Review degradation mechanisms for stainless steel and carbon steel and determine their relevance to the transfer line piping; (3) Review the transfer piping inspection data; (4) Life estimation calculations for the transfer lines; and (5) A Fitness-For-Service evaluation for one of the transfer line jackets. The evaluation concluded that the transfer line system piping has performed well for over fifty years. Although there have been instances of failures of the stainless steel core pipe during off-normal service, no significant

  10. 40 CFR 63.984 - Fuel gas systems and processes to which storage vessel, transfer rack, or equipment leak...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Fuel Gas System or a Process § 63.984 Fuel gas systems and processes to which storage vessel, transfer... 40 Protection of Environment 11 2012-07-01 2012-07-01 false Fuel gas systems and processes to which storage vessel, transfer rack, or equipment leak regulated material emissions are routed....

  11. 40 CFR 63.984 - Fuel gas systems and processes to which storage vessel, transfer rack, or equipment leak...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Fuel Gas System or a Process § 63.984 Fuel gas systems and processes to which storage vessel, transfer... 40 Protection of Environment 11 2014-07-01 2014-07-01 false Fuel gas systems and processes to which storage vessel, transfer rack, or equipment leak regulated material emissions are routed....

  12. Describing the signal-transfer characteristics of asymmetrical radiographic screen-film systems.

    PubMed

    Van Metter, R

    1992-01-01

    The measurement of modulation transfer function for radiographic screen-film systems depends critically upon a proper linearization of the measured line spread function. This is normally done by photographic photometry (i.e., using the measured density versus log exposure relationship to transform the density line spread function into an exposure line spread function). It has been long appreciated that this procedure may fail for asymmetrical dual screen systems that use film with emulsion coated on both sides of the support. The advent of asymmetrical and near-zero crossover films that can be used with highly asymmetric screen pairs has prompted a reinvestigation of these concerns about the definition and measurement of modulation transfer function. For such cases, it is useful to define the contrast transfer function, which is a function of exposure and spatial frequency. When normalized by its zero frequency value the contrast transfer function can serve as the "effective MTF" for low-contrast input signals in such systems. In the limit of symmetrical systems this quantity approaches the conventionally measured MTF. The utility of this approach is demonstrated by applying it to a commercially available asymmetrical screen-film combination.

  13. A Wireless Magnetic Resonance Energy Transfer System for Micro Implantable Medical Sensors

    PubMed Central

    Li, Xiuhan; Zhang, Hanru; Peng, Fei; Li, Yang; Yang, Tianyang; Wang, Bo; Fang, Dongming

    2012-01-01

    Based on the magnetic resonance coupling principle, in this paper a wireless energy transfer system is designed and implemented for the power supply of micro-implantable medical sensors. The entire system is composed of the in vitro part, including the energy transmitting circuit and resonant transmitter coils, and in vivo part, including the micro resonant receiver coils and signal shaping chip which includes the rectifier module and LDO voltage regulator module. Transmitter and receiver coils are wound by Litz wire, and the diameter of the receiver coils is just 1.9 cm. The energy transfer efficiency of the four-coil system is greatly improved compared to the conventional two-coil system. When the distance between the transmitter coils and the receiver coils is 1.5 cm, the transfer efficiency is 85% at the frequency of 742 kHz. The power transfer efficiency can be optimized by adding magnetic enhanced resonators. The receiving voltage signal is converted to a stable output voltage of 3.3 V and a current of 10 mA at the distance of 2 cm. In addition, the output current varies with changes in the distance. The whole implanted part is packaged with PDMS of excellent biocompatibility and the volume of it is about 1 cm3. PMID:23112600

  14. Sample transfer system for surface studies in wide pressure range (10-7-106 Pa)

    NASA Astrophysics Data System (ADS)

    Ichikawa, Shinichi; Wilson, Mahlon S.

    1987-02-01

    An inexpensive sample transfer system suitable for surface studies with in situ prepared model catalysts is described. Experiments from ultrahigh vacuum to 10 atm and 50-cm travel with negligible pressure spikes were made possible by the use of double-seal glands with spring-loaded Teflon O-rings and a guided rotational transport rod.

  15. Students Who Transfer between Oregon Community Colleges and Oregon University System Institutions: What the Data Say.

    ERIC Educational Resources Information Center

    Oregon Univ. System, Eugene. Office of Academic Affairs.

    This report provides a follow-up to the 1999 "Plan for Course and Credit Transfer Between Oregon Community Colleges and Oregon University System Institutions" by specifically responding to its call for ongoing data-collection and research efforts. The purposes of this report are as follows: (1) to summarize the results of four years of…

  16. Building World-Market Competitors: Technology Transfer and the Illinois Community College System. 1990 Status Report.

    ERIC Educational Resources Information Center

    Bragg, Debra D.

    In 1990, the Illinois Council of Public Community College Presidents (ICPCCP) commissioned a survey to document the current capacity and future potential of the Illinois Community College System (ICCS) to provide technology transfer assistance to the commercial marketplace and the public sector. An extensive questionnaire was developed and mailed…

  17. European Credit Transfer and Accumulation System: An Alternative Way to Calculate the ECTS Grades

    ERIC Educational Resources Information Center

    Grosges, Thomas; Barchiesi, Dominique

    2007-01-01

    The European Credit Transfer and Accumulation System (ECTS) has been developed and instituted to facilitate student mobility and academic recognition. This paper presents, discusses, and illustrates the pertinence and the limitation of the current statistical distribution of the ECTS grades, and we propose an alternative way to calculate the ECTS…

  18. The Learning Transfer System Inventory (LTSI) in Ukraine: The Cross-Cultural Validation of the Instrument

    ERIC Educational Resources Information Center

    Yamkovenko, Bogdan V.; Holton, Elwood, III; Bates, R. A.

    2007-01-01

    Purpose: The purpose of this research is to expand cross-cultural research and validate the Learning Transfer System Inventory in Ukraine. The researchers seek to translate the LTSI into Ukrainian and investigate the internal structure of this translated version of the questionnaire. Design/methodology/approach: The LTSI is translated into…

  19. Faculty-Determined Course Equivalency: The Key to Ohio's Transfer Mobility System

    ERIC Educational Resources Information Center

    Compton, Paula K.; Tafel, Jonathan; Law, Joe; Gustafson, Robert

    2012-01-01

    For more than two decades, the vision of a statewide system of student mobility has driven Ohio's articulation and transfer initiatives, which guarantee that specific courses will be applied to degrees and certificates at public two- and four-year postsecondary institutions. This chapter outlines how Ohio developed a comprehensive, guaranteed…

  20. Teaching Applied Genetics and Molecular Biology to Agriculture Engineers. Application of the European Credit Transfer System

    ERIC Educational Resources Information Center

    Weiss, J.; Egea-Cortines, M.

    2008-01-01

    We have been teaching applied molecular genetics to engineers and adapted the teaching methodology to the European Credit Transfer System. We teach core principles of genetics that are universal and form the conceptual basis of most molecular technologies. The course then teaches widely used techniques and finally shows how different techniques…

  1. The Laboratory as a Tool for Learning Thermodynamics, Heat Transfer, and Thermal Systems.

    ERIC Educational Resources Information Center

    Neto, Alberto Hernandez; Tribess, Arlindo; Fiorelli, Flavio Augusto Sanzogo

    The consolidation of the theoretical concepts as well as the use and learning of experimental techniques that are compatible with the technological evolution has been the main goals in Thermodynamics and Heat Transfer and Thermal Systems Laboratories at Escola Politecnica of University of Sao Paulo. The infra-structure and experimental benches in…

  2. Development of enhanced heat transfer/transport/storage slurries for thermal-system improvement

    SciTech Connect

    Kasza, K.E.; Chen, M.M.

    1983-01-01

    This paper presents a formulation of a new concept for improving thermal-system performance by utilizing the combined mechanisms of enhanced heat transfer, transport, and thermal-energy storage associated with a phase-change slurry as the working fluid.

  3. Radiative transfer in nonuniformly refracting layered media: atmosphere-ocean system.

    PubMed

    Jin, Z; Stamnes, K

    1994-01-20

    We have applied the discrete-ordinate method to solve the radiative-transfer problem pertaining to a system consisting of two strata with different indices of refraction. The refraction and reflection at the interface are taken into account. The relevant changes (as compared with the standard problem with a constant index of refraction throughout the medium) in formulation and solution of the radiative-transfer equation, including the proper application of interface and boundary conditions, are described. Appropriate quadrature points (streams) and weights are chosen for the interface-continuity relations. Examples of radiative transfer in the coupled atmosphere-ocean system are provided. To take into account the region of total reflection in the ocean, additional angular quadrature points are required, compared with those used in the atmosphere and in the refractive region of the ocean that communicates directly with the atmosphere. To verify the model we have tested for energy conservation. We also discuss the effect of the number of streams assigned to the refractive region and the total reflecting region on the convergence. Our results show that the change in the index of refraction between the two strata significantly affects the radiation field. The radiative-transfer model we present is designed for application to the atmosphere-ocean system, but it can be applied to other systems that need to consider the change in the index of refraction between two strata. PMID:20862035

  4. Collaboration for Student Success: A System for Providing Transfer Student Performance Information to Feeder Institutions.

    ERIC Educational Resources Information Center

    Thompson, Susan

    Southwest Texas State (SWT) University has developed a system of communication with two-year community colleges that aims to provide information about new student performance and identify student needs. About 60% of the 7,000 new undergraduate students first enrolling in SWT each year are transfer students. In 1992, about 60% of new students at…

  5. West Valley transfer cart control system design description. Environmental Restoration and Waste Management Program

    SciTech Connect

    Bradley, E.C.; Crutcher, R.I.; Halliwell, J.W.; Hileman, M.S.; Moore, M.R.; Nodine, R.N.; Ruppel, F.R.; Vandermolen, R.I.

    1993-01-01

    Detail design of the control system for the West Valley Nuclear Services Vitrification Facility transfer cart has been completed by Oak Ridge National Laboratory. This report documents the requirements and describes the detail design of that equipment and control software. Copies of significant design documents including analysis and testing reports and design drawings are included in the Appendixes.

  6. Slim accretion discs with different viscosity prescriptions

    NASA Astrophysics Data System (ADS)

    Szuszkiewicz, Ewa

    1990-05-01

    The variability of X-ray sources powered by accretion may be connected to thermal instabilities in the innermost parts of slim disks. The time-scales of variability predicted by the theory with the standard alpha-viscosity prescription agree with those observed in a wide range of sources. The amplitudes (3-4 orders of magnitude in luiminosity) are correctly predicted for X-ray transient sources, but in general are too big for quasars, Seyferts, galactic blackhole candidates and LMXBs. It is shown that a slight modification of the viscosity prescription can offer a much better agreement with observations.

  7. Sale of prescription drugs over the Internet.

    PubMed

    Armstrong, K; Bloom, B S

    1999-01-01

    Online drugstores represent one of the hottest categories in electronic commerce. The Internet offers great promise in expanding access to prescription drugs for the disabled, the elderly, and people living in rural areas. But with this promise comes the danger of eliminating the safeguards that protect consumers from inappropriate use of medications and adverse drug events. This Issue Brief highlights two studies that investigate the availability of prescription drugs over the Internet, and focuses on the alarming ease with which consumers can obtain drugs without seeing a physician or a pharmacist. PMID:12523341

  8. Failsafe data transfer of important hydrological values for early warning systems

    NASA Astrophysics Data System (ADS)

    Klock, E.; Stadler, H.; Pevny, G.; Jakubiec, A.; Skritek, P.

    2009-04-01

    For applications like early warning systems and decision support systems (DSS) for quality monitoring of drinking water, especially from karst aquifers, or for flood forecasting and warning systems it is necessary to transmit important hydrological data, e.g. the gauge height and different quality parameter (e.g. SAC, turbidity) in "near real-time" from a measuring station to a Central Monitoring Station (CMS). Thereby it is very important to guarantee a consistent and failsafe data transfer. These measured values are stored in a data base and can be used for further computations or data can be requested in terms of tables or graphics via the internet. This online monitoring system of important hydrological data works automated and maintenance of the measuring site is economized more and more. A special feature of this early warning systems is the possibility of automated alarm messages by exceeding thresholds, implausible developing of values or other criteria via Email or SMS to specific users or a local service team which can verify the data. In areas with terrestrial infrastructure GPRS (General Packet Radio Service) can be used as transmission medium which enables a fast and cost-efficient transfer of data from the measurement stations to the CMS. One big problem with such terrestrial communication systems is the risk of default when their networks are overloaded, as it can happen during crisis situations (e.g. flood events, thunderstorms). Especially for the surveillance of karst springs it is very important to get data also during times of increased hazards. Therefore it is necessary to have the possibility to transmit the measured values also via communication satellites when a terrestrial infrastructure is not available. The system presented here is a combination of bidirectional data transmission with a terrestrial communication system and a "near real-time" satellite communication by means of low earth orbiting satellites. Typically periodical

  9. Purchasing prescription medication in Mexico without a prescription. The experience at the border.

    PubMed Central

    Casner, P. R.; Guerra, L. G.

    1992-01-01

    Prescription medication can often be purchased in Mexico without a physician's prescription. United States residents living along the border may have access to dangerous medications by crossing the border and purchasing them in Mexican pharmacies. We sought to determine the extent and frequency of this behavior in a sample of our ambulatory clinic population. Patients from the Texas Tech University Internal Medicine Clinic were surveyed to collect information about their use of medications, use of alternative sources of health care in Mexico, and purchasing of prescription medication in Juarez, Mexico. More than 80% of patients stated they had purchased prescription-type medication at a pharmacy without a physician's prescription. The most common reasons for buying prescription medication in Mexico were because it was less expensive or because a prescription was not necessary. These data indicate a potential for US residents along the border to take medications in an unregulated manner, a practice that could pose problems for health care providers on both sides of the border. Images PMID:1595276

  10. Purchasing prescription medication in Mexico without a prescription. The experience at the border.

    PubMed

    Casner, P R; Guerra, L G

    1992-05-01

    Prescription medication can often be purchased in Mexico without a physician's prescription. United States residents living along the border may have access to dangerous medications by crossing the border and purchasing them in Mexican pharmacies. We sought to determine the extent and frequency of this behavior in a sample of our ambulatory clinic population. Patients from the Texas Tech University Internal Medicine Clinic were surveyed to collect information about their use of medications, use of alternative sources of health care in Mexico, and purchasing of prescription medication in Juarez, Mexico. More than 80% of patients stated they had purchased prescription-type medication at a pharmacy without a physician's prescription. The most common reasons for buying prescription medication in Mexico were because it was less expensive or because a prescription was not necessary. These data indicate a potential for US residents along the border to take medications in an unregulated manner, a practice that could pose problems for health care providers on both sides of the border. PMID:1595276

  11. The Constitution's Prescription for Freedom.

    ERIC Educational Resources Information Center

    Peach, Lucinda

    1986-01-01

    Examines how the framers of the Constitution came to choose our system of government, how that system was designed to function, and how the separation of powers has served to maintain our democracy despite attempts to violate it. (JDH)

  12. Method and apparatus for transfer function simulator for testing complex systems

    NASA Technical Reports Server (NTRS)

    Kavaya, M. J. (Inventor)

    1985-01-01

    A method and apparatus for testing the operation of a complex stabilization circuit in a closed loop system is presented. The method is comprised of a programmed analog or digital computing system for implementing the transfer function of a load thereby providing a predictable load. The digital computing system employs a table stored in a microprocessor in which precomputed values of the load transfer function are stored for values of input signal from the stabilization circuit over the range of interest. This technique may be used not only for isolating faults in the stabilization circuit, but also for analyzing a fault in a faulty load by so varying parameters of the computing system as to simulate operation of the actual load with the fault.

  13. Test of an orbiting hydrogen maser clock system using laser time transfer

    NASA Technical Reports Server (NTRS)

    Vessot, Robert F. C.; Mattison, Edward M.; Nystrom, G. U.; Decher, Rudolph

    1992-01-01

    We describe a joint Smithsonian Astrophysical Laboratory/National Aeronautics and Space Administration (SAO/NASA) program for flight testing a atomic hydrogen maser clock system designed for long-term operation in space. The clock system will be carried by a shuttle-launched EURECA spacecraft. Comparisons with earth clocks to measure the clock's long-term frequency stability (tau = 10(exp 4) seconds) will be made using laser time transfer from existing NASA laser tracking stations. We describe the design of the maser clock and its control systems, and the laser timing technique. We describe the precision of station time synchronization and the limitations in the comparison between the earth and space time scales owing to gravitational and relativistic effects. We will explore the implications of determining the spacecraft's location by an on-board Global Position System (GPS) receiver, and of using microwave techniques for time and frequency transfer.

  14. Efficient and decentralized data transfer architecture for component based embedded systems

    NASA Astrophysics Data System (ADS)

    de la Fuente, David; Barba, Jesús; Dondo, Julio; Rincón, Fernando; Santofimia, María. J.; López, Juan Carlos

    2013-05-01

    Multimedia embedded systems usually expose a chain-based architecture where each functional stage of the media algorithm is encapsulated in a media core in charge of processing the stream of data. Therefore, in this kind of systems, the interconnection mechanisms are key to cope with the enormous bandwidth demands. In this paper, we present a decentralized data transfer architecture for bus based embedded systems. The communication infrastructure introduced here is parameterizable, dynamically configurable and optimized for hardware media component processing platforms. Unlike conventional approaches, where a software control routine has to oversee all the steps of the data exchanging process (e.g. DMA configuration, trapping interruptions, ...), our approach moves such responsibility to the hardware components which are highly autonomous. This has a positive impact in performance since the processor is not mediating in every single data transfer that takes place in the system.

  15. Investigating potential transferability of place-based research in land system science

    NASA Astrophysics Data System (ADS)

    Václavík, Tomáš; Langerwisch, Fanny; Cotter, Marc; Fick, Johanna; Häuser, Inga; Hotes, Stefan; Kamp, Johannes; Settele, Josef; Spangenberg, Joachim H.; Seppelt, Ralf

    2016-09-01

    Much of our knowledge about land use and ecosystem services in interrelated social-ecological systems is derived from place-based research. While local and regional case studies provide valuable insights, it is often unclear how relevant this research is beyond the study areas. Drawing generalized conclusions about practical solutions to land management from local observations and formulating hypotheses applicable to other places in the world requires that we identify patterns of land systems that are similar to those represented by the case study. Here, we utilize the previously developed concept of land system archetypes to investigate potential transferability of research from twelve regional projects implemented in a large joint research framework that focus on issues of sustainable land management across four continents. For each project, we characterize its project archetype, i.e. the unique land system based on a synthesis of more than 30 datasets of land-use intensity, environmental conditions and socioeconomic indicators. We estimate the transferability potential of project research by calculating the statistical similarity of locations across the world to the project archetype, assuming higher transferability potentials in locations with similar land system characteristics. Results show that areas with high transferability potentials are typically clustered around project sites but for some case studies can be found in regions that are geographically distant, especially when values of considered variables are close to the global mean or where the project archetype is driven by large-scale environmental or socioeconomic conditions. Using specific examples from the local case studies, we highlight the merit of our approach and discuss the differences between local realities and information captured in global datasets. The proposed method provides a blueprint for large research programs to assess potential transferability of place-based studies to other

  16. Information transfer via implicit encoding with delay time modulation in a time-delay system

    NASA Astrophysics Data System (ADS)

    Kye, Won-Ho

    2012-08-01

    A new encoding scheme for information transfer with modulated delay time in a time-delay system is proposed. In the scheme, the message is implicitly encoded into the modulated delay time. The information transfer rate as a function of encoding redundancy in various noise scales is presented and it is analyzed that the implicit encoding scheme (IES) has stronger resistance against channel noise than the explicit encoding scheme (EES). In addition, its advantages in terms of secure communication and feasible applications are discussed.

  17. Short-lived electron transfer in donor-bridge-acceptor systems

    NASA Astrophysics Data System (ADS)

    Psiachos, D.

    2016-10-01

    We investigate time-dependent electron transfer (ET) in benchmark donor-bridge-acceptor systems. For the small bridge sizes studied, we obtain results far different from the perturbation theory which underlies scattering-based approaches, notably a lack of destructive interference in the ET for certain arrangements of bridge molecules. We also calculate wavepacket transmission in the non-steady-state regime, finding a featureless spectrum, while for the current we find two types of transmission: sequential and direct, where in the latter, the current transmission increases as a function of the energy of the transferred electron, a regime inaccessible by conventional scattering theory.

  18. [Prescription of generic drugs to privately insured persons].

    PubMed

    Wild, Frank

    2012-12-01

    The system-related differences between private health insurance and statutory health insurance in Germany could lead to divergent prescriptions of medication. The study shows that doctors whose privately insured patients have been prescribed the same medication over a long period of time will frequently continue to prescribe the original medication even after its patent protection has expired. By contrast, patients in the statutory health insurance system will usually be switched to generic drugs. However, physicians prescribing medication to a privately insured person for the first time will frequently select generics in the first place. PMID:23236709

  19. [Mining analysis on composition and medication of menstruation prescriptions in Fu Qingzhu's Obstetrics and Gynecology].

    PubMed

    Zhu, Jia-qing; Che, Yu-xia

    2015-04-01

    In this paper, menstruation prescriptions were selected from "Fu Qingzhu's Obstetrics and Gynecology" and analyzed by using GRI algorithm, correlation analysis, hierarchical clustering method through SPSS, Clementine and traditional Chinese medicine (TCM) inheritance auxiliary systems, in order to screen out 15 menopathy prescriptions, which involve 45 traditional Chinese medicine herbs. In the study, blood-tonifying and qi-tonifying herbs were found to be frequent in the prescriptions. The most frequent single herb was white paeony root, accounting for 9.6% in the total number of prescriptions; The most frequent herb pairs were white paeony root-radix rehmanniae preparata and paeony root-angelica sinensis. Among Fu Shan's menopathy prescriptions, 61 herbal pairs showed a correlation coefficient exceeding 0.05, which evolved into 16 pairs of core combinations. The analysis showed that menopathy prescriptions in volume 1 of "Fu Qingzhu's Obstetrics and Gynecology" focused on tonic traditional Chinese medicines involving liver, spleen and kidney and were adjusted according to changes in qi, blood, cold, hot and wet, which could provide a specific reference for further studies on Fu Shan's academic thoughts and traditional Chinese medicine clinical treatment of menopathy.

  20. Behavioural screening of zebrafish using neuroactive traditional Chinese medicine prescriptions and biological targets

    PubMed Central

    Wang, Ya-Nan; Hou, Yuan-Yuan; Sun, Ming-Zhu; Zhang, Chun-Yang; Bai, Gang; Zhao, Xin; Feng, Xi-Zeng

    2014-01-01

    The mechanism of the therapeutic action of antidepressants remains uncertain in traditional Chinese medicine (TCM). In this study, we selected 7 classical TCM prescriptions and utilised an automatic video-tracking system to monitor the rest/wake behaviour of larval zebrafish at 4 days post-fertilisation (dpf) for 48 hours. We found that the curative effects of the prescriptions were dose-dependent. K-means clustering was performed according to the shared behavioural phenotypes of the zebrafish. The results revealed that the rest/wake behavioural profiles induced by the same class of prescriptions were similar. A correlation analysis was conducted between the TCM prescriptions and the known compounds. The results showed that the TCM prescriptions correlated well with some well-known compounds. Therefore, we predicted that they may share a similar mechanism of action. This paper describes the first study to combine TCM research with zebrafish rest/wake behaviour in vivo and presents a powerful approach for the discovery of the mechanism of action of TCM prescriptions. PMID:24931174

  1. Time trends of antidepressant drug prescriptions in men versus women in a geographically defined US population

    PubMed Central

    Zhong, Wenjun; Kremers, Hilal Maradit; Yawn, Barbara P.; Bobo, William V.; St Sauver, Jennifer L.; Ebbert, Jon O.; Rutten, Lila J.; Jacobson, Debra J.; Brue, Scott M.; Rocca, Walter A.

    2014-01-01

    Purpose To study time trends of antidepressant drug (AD) prescriptions in a geographically defined US population between 2005 and 2011 for men and women separately. Methods Using the Rochester Epidemiology Project medical records-linkage system, we identified all Olmsted County, MN residents who received AD outpatient prescriptions between 2005 and 2011 (seven years). We calculated the annual age-and sex-specific prevalence over seven years, and used generalized estimating equation models to test for time trends. Results The prevalence of subjects receiving at least one AD prescription was approximately two times higher in women than men consistently across the seven years of the study. The standardized annual prevalence increased from 10.8% in 2005 to 14.4% in 2011 overall, from 7.0% in 2005 to 9.9% in 2011 for men, and from 14.4% in 2005 to 18.6% in 2011 for women. The absolute percent increase was greater in women (4.2% vs. 2.9%; standardized); however, the relative percent increase was greater in men (41.4% vs. 29.2%; standardized). The relative percent increase was greater in the age group 65+ years for both men and women. Conclusions AD prescriptions are increasing over time, especially in the elderly. Women receive more AD prescriptions than men. However, the relative increase in AD prescriptions over time is greater in men than women. PMID:25113318

  2. Behavioural screening of zebrafish using neuroactive traditional Chinese medicine prescriptions and biological targets

    NASA Astrophysics Data System (ADS)

    Wang, Ya-Nan; Hou, Yuan-Yuan; Sun, Ming-Zhu; Zhang, Chun-Yang; Bai, Gang; Zhao, Xin; Feng, Xi-Zeng

    2014-06-01

    The mechanism of the therapeutic action of antidepressants remains uncertain in traditional Chinese medicine (TCM). In this study, we selected 7 classical TCM prescriptions and utilised an automatic video-tracking system to monitor the rest/wake behaviour of larval zebrafish at 4 days post-fertilisation (dpf) for 48 hours. We found that the curative effects of the prescriptions were dose-dependent. K-means clustering was performed according to the shared behavioural phenotypes of the zebrafish. The results revealed that the rest/wake behavioural profiles induced by the same class of prescriptions were similar. A correlation analysis was conducted between the TCM prescriptions and the known compounds. The results showed that the TCM prescriptions correlated well with some well-known compounds. Therefore, we predicted that they may share a similar mechanism of action. This paper describes the first study to combine TCM research with zebrafish rest/wake behaviour in vivo and presents a powerful approach for the discovery of the mechanism of action of TCM prescriptions.

  3. SLUDGE TREATMENT PROJECT ENGINEERED CONTAINER RETRIEVAL AND TRANSFER SYSTEM PRELIMINARY DESIGN HAZARD ANALYSIS SUPPLEMENT 1

    SciTech Connect

    FRANZ GR; MEICHLE RH

    2011-07-18

    This 'What/If' Hazards Analysis addresses hazards affecting the Sludge Treatment Project Engineered Container Retrieval and Transfer System (ECRTS) NPH and external events at the preliminary design stage. In addition, the hazards of the operation sequence steps for the mechanical handling operations in preparation of Sludge Transport and Storage Container (STSC), disconnect STSC and prepare STSC and Sludge Transport System (STS) for shipping are addressed.

  4. Building Thermal Envelope Systems and Materials (BTESM) and research utilization/technology transfer

    SciTech Connect

    Burn, G.

    1990-07-01

    The Monthly Report of the Building Thermal Envelope Systems and Materials (BTESM) Programs is a monthly update of both in-house ORNL projects and subcontract activities in the research areas of building materials, wall systems, foundations, roofs, building diagnostics, and research utilization and technology transfer. Presentations are not stand-alone paragraphs every month. Their principal values are the short-time lapse between accomplishment and reporting and their evolution over a period of several months..

  5. Project W-314 Specific Test and Evaluation Plan for 200E Waste Transfer System

    SciTech Connect

    HAMMERS, J.S.

    2000-02-25

    The purpose of this Specific Test and Evaluation Plan (STEP) is to provide a detailed written plan for the systematic testing of the newly constructed 200E Waste Transfer System in the W-314 Project. The STEP provides the outline for test and evaluation methods that verify the system's performance and compliance to the established Project design criteria. The STEP is a ''lower tier'' document based on the W-314 Test & Evaluation Plan (TEP).

  6. The application test system: An approach to technology transfer. [USDA aerospace and remote sensing information requirements

    NASA Technical Reports Server (NTRS)

    Aaronson, A. C.; Buelow, K.; David, F. C.; Packard, R. L.; Ravet, F. W. (Principal Investigator)

    1979-01-01

    The latest satellite and computer processing and analysis technologies were tested and evaluated in terms of their application feasibility. Technologies evaluated include those developed, tested, and evaluated by the LACIE, as well as candidate technologies developed by the research community and private industry. The implementation of the applications test system and the technology transfer experience between the LACIE and the applications test system is discussed highlighting the approach, the achievements, and the shortcomings.

  7. Design Review Closure Report for the SY-101 Rapid Transfer System

    SciTech Connect

    POWELL, W.J.

    1999-11-29

    The purpose of this report, is to document closure of design review open items, resulting from design reviews conducted for the SY-101 Respond And Pump In Days (RAPID) Transfer System. Results of the various design reviews were documented in the Design Review Report for The SY-101 Rapid Mitigation System, HNF-4519. In that report, twenty-three open items were identified. In this report the 23 items are reviewed and statused.

  8. Predicting oxygen transfer of fine bubble diffused aeration systems--model issued from dimensional analysis.

    PubMed

    Gillot, S; Capela-Marsal, S; Roustan, M; Héduit, A

    2005-04-01

    The standard oxygenation performances of fine bubble diffused aeration systems in clean water, measured in 12 cylindrical tanks (water depth from 2.4 to 6.1m), were analysed using dimensional analysis. A relationship was established to estimate the scale-up factor for oxygen transfer, the transfer number (N(T)) The transfer number, which is written as a function of the oxygen transfer coefficient (k(L)a(20)), the gas superficial velocity (U(G)), the kinematic viscosity of water (nu) and the acceleration due to gravity (g), has the same physical meaning as the specific oxygen transfer efficiency. N(T) only depends on the geometry of the tank/aeration system [the total surface of the perforated membrane (S(p)), the surface of the tank (S) or its diameter (D), the total surface of the zones covered by the diffusers ("aerated area", S(a)) and the submergence of the diffusers (h)]. This analysis allowed to better describe the mass transfer in cylindrical tanks. Within the range of the parameters considered, the oxygen transfer coefficient (k(L)a(20)) is an increasing linear function of the air flow rate. For a given air flow rate and a given tank surface area, k(L)a(20) decreases with the water depth (submergence of the diffusers). For a given water depth, k(L)a(20) increases with the number of diffusers, and, for an equal number of diffusers, with the total area of the zones covered by the diffusers. The latter result evidences the superiority of the total floor coverage over an arrangement whereby the diffusers are placed on separate grids. The specific standard oxygen transfer efficiency is independent of the air flow rate and the water depth, the drop in the k(L)a(20) being offset by the increase of the saturation concentration. For a given tank area, the impact of the total surface of the perforated membrane (S(p)) and of the aerated area (S(a)) is the same as on the oxygen transfer coefficient. PMID:15862338

  9. Proton-Coupled Electron Transfer in Biology: Results from Synergistic Studies in Natural and Model Systems

    PubMed Central

    Reece, Steven Y.; Nocera, Daniel G.

    2015-01-01

    Proton-coupled electron transfer (PCET) underpins energy conversion in biology. PCET may occur with the unidirectional or bidirectional transfer of a proton and electron and may proceed synchronously or asynchronously. To illustrate the role of PCET in biology, this review presents complementary biological and model systems that explore PCET in electron transfer (ET) through hydrogen bonds [azurin as compared to donor-acceptor (D–A) hydrogen-bonded networks], the activation of C–H bonds [alcohol dehydrogenase and soybean lipoxygenase (SLO) as compared to Fe(III) metal complexes], and the generation and transport of amino acid radicals [photosystem II (PSII) and ribonucleotide reductase (RNR)as compared to tyrosine-modified photoactive Re(I) and Ru(II) complexes]. In providing these comparisons, the fundamental principles of PCET in biology are illustrated in a tangible way. PMID:19344235

  10. Lipid Transfer Proteins As Components of the Plant Innate Immune System: Structure, Functions, and Applications

    PubMed Central

    Finkina, E. I.; Melnikova, D. N.; Bogdanov, I. V.; Ovchinnikova, T. V.

    2016-01-01

    Among a variety of molecular factors of the plant innate immune system, small proteins that transfer lipids and exhibit a broad spectrum of biological activities are of particular interest. These are lipid transfer proteins (LTPs). LTPs are interesting to researchers for three main features. The first feature is the ability of plant LTPs to bind and transfer lipids, whereby these proteins got their name and were combined into one class. The second feature is that LTPs are defense proteins that are components of plant innate immunity. The third feature is that LTPs constitute one of the most clinically important classes of plant allergens. In this review, we summarize the available data on the plant LTP structure, biological properties, diversity of functions, mechanisms of action, and practical applications, emphasizing their role in plant physiology and their significance in human life. PMID:27437139

  11. Centralized PI control for high dimensional multivariable systems based on equivalent transfer function.

    PubMed

    Luan, Xiaoli; Chen, Qiang; Liu, Fei

    2014-09-01

    This article presents a new scheme to design full matrix controller for high dimensional multivariable processes based on equivalent transfer function (ETF). Differing from existing ETF method, the proposed ETF is derived directly by exploiting the relationship between the equivalent closed-loop transfer function and the inverse of open-loop transfer function. Based on the obtained ETF, the full matrix controller is designed utilizing the existing PI tuning rules. The new proposed ETF model can more accurately represent the original processes. Furthermore, the full matrix centralized controller design method proposed in this paper is applicable to high dimensional multivariable systems with satisfactory performance. Comparison with other multivariable controllers shows that the designed ETF based controller is superior with respect to design-complexity and obtained performance.

  12. Role of inorganic phosphate during electron transfer in the redox system NADH+flavin

    NASA Astrophysics Data System (ADS)

    Lozinova, T. A.; Brzhevskaya, O. N.; Kisin, A. V.; Nosova, V. M.; Rykov, S. V.; Tychinskaya, L. Yu.

    2006-05-01

    We have used 31P NMR and EPR to study the effect of inorganic phosphate (Pi) on the process of electron transfer in oxidation of reduced nicotinamide adenine dinucleotide (NADH) by flavin in aqueous solutions. Observation of a significant (up to 40%) drop in the integrated intensity of the 31P NMR signal for the inorganic phosphate over the course of the reaction is interpreted as a manifestation of the effect of chemically induced polarization of the phosphorus nuclei during singlet-triplet conversion in charge-transfer complexes [NADH…Pi], and is evidence for a possible catalytic role for Pi in processes involving transfer of an electron (hydrogen atom) from NADH to appropriate acceptors. The results presented support the possibility of direct involvement of Pi in a chain of one-electron conversions in chemical systems.

  13. Anion Photoelectron Spectroscopy of the Homogenous 2-Hydroxypyridine Dimer Electron Induced Proton Transfer System

    NASA Astrophysics Data System (ADS)

    Vlk, Alexandra; Stokes, Sarah; Wang, Yi; Hicks, Zachary; Zhang, Xinxing; Blando, Nicolas; Frock, Andrew; Marquez, Sara; Bowen, Kit; Bowen Lab JHU Team

    Anion photoelectron spectroscopic (PES) and density functional theory (DFT) studies on the dimer anion of (2-hydroxypyridine)2-are reported. The experimentally measured vertical detachment energy (VDE) of 1.21eV compares well with the theoretically predicted values. The 2-hydroxypyridine anionic dimer system was investigated because of its resemblance to the nitrogenous heterocyclic pyrimidine nucleobases. Experimental and theoretical results show electron induced proton transfer (EIPT) in both the lactim and lactam homogeneous dimers. Upon electron attachment, the anion can serve as the intermediate between the two neutral dimers. A possible double proton transfer process can occur from the neutral (2-hydroxypyridine)2 to (2-pyridone)2 through the dimer anion. This potentially suggests an electron catalyzed double proton transfer mechanism of tautomerization. Research supported by the NSF Grant No. CHE-1360692.

  14. Charge transfer in strongly correlated systems: An exact diagonalization approach to model Hamiltonians

    SciTech Connect

    Schöppach, Andreas; Gnandt, David; Koslowski, Thorsten

    2014-04-07

    We study charge transfer in bridged di- and triruthenium complexes from a theoretical and computational point of view. Ab initio computations are interpreted from the perspective of a simple empirical Hamiltonian, a chemically specific Mott-Hubbard model of the complexes' π electron systems. This Hamiltonian is coupled to classical harmonic oscillators mimicking a polarizable dielectric environment. The model can be solved without further approximations in a valence bond picture using the method of exact diagonalization and permits the computation of charge transfer reaction rates in the framework of Marcus' theory. In comparison to the exact solution, the Hartree-Fock mean field theory overestimates both the activation barrier and the magnitude of charge-transfer excitations significantly. For triruthenium complexes, we are able to directly access the interruthenium antiferromagnetic coupling strengths.

  15. Convective Heat Transfer in the Reusable Solid Rocket Motor of the Space Transportation System

    NASA Technical Reports Server (NTRS)

    Ahmad, Rashid A.; Cash, Stephen F. (Technical Monitor)

    2002-01-01

    This simulation involved a two-dimensional axisymmetric model of a full motor initial grain of the Reusable Solid Rocket Motor (RSRM) of the Space Transportation System (STS). It was conducted with CFD (computational fluid dynamics) commercial code FLUENT. This analysis was performed to: a) maintain continuity with most related previous analyses, b) serve as a non-vectored baseline for any three-dimensional vectored nozzles, c) provide a relatively simple application and checkout for various CFD solution schemes, grid sensitivity studies, turbulence modeling and heat transfer, and d) calculate nozzle convective heat transfer coefficients. The accuracy of the present results and the selection of the numerical schemes and turbulence models were based on matching the rocket ballistic predictions of mass flow rate, head end pressure, vacuum thrust and specific impulse, and measured chamber pressure drop. Matching these ballistic predictions was found to be good. This study was limited to convective heat transfer and the results compared favorably with existing theory. On the other hand, qualitative comparison with backed-out data of the ratio of the convective heat transfer coefficient to the specific heat at constant pressure was made in a relative manner. This backed-out data was devised to match nozzle erosion that was a result of heat transfer (convective, radiative and conductive), chemical (transpirating), and mechanical (shear and particle impingement forces) effects combined.

  16. Estimating the transfer function of the cantilever in atomic force microscopy: A system identification approach

    NASA Astrophysics Data System (ADS)

    Stark, Martin; Guckenberger, Reinhard; Stemmer, Andreas; Stark, Robert W.

    2005-12-01

    Dynamic atomic force microscopy (AFM) offers many opportunities for the characterization and manipulation of matter on the nanometer scale with a high temporal resolution. The analysis of time-dependent forces is basic for a deeper understanding of phenomena such as friction, plastic deformation, and surface wetting. However, the dynamic characteristics of the force sensor used for such investigations are determined by various factors such as material and geometry of the cantilever, detection alignment, and the transfer characteristics of the detector. Thus, for a quantitative investigation of surface properties by dynamic AFM an appropriate system identification procedure is required, characterizing the force sensor beyond the usual parameters spring constant, quality factor, and detection sensitivity. Measurement of the transfer function provides such a characterization that fully accounts for the dynamic properties of the force sensor. Here, we demonstrate the estimation of the transfer function in a bandwidth of 1MHz from experimental data. To this end, we analyze the signal of the vibrations induced by snap-to-contact and snap-off-contact events. For the free cantilever, we determine both a parameter-free estimate [empirical transfer function estimate (ETFE)] and a parametric estimate of the transfer function. For the surface-coupled cantilever the ETFE is obtained. These identification procedures provide an intrinsic calibration as they dispense largely with a priori knowledge about the force sensor.

  17. Quantum electrodynamical theory of high-efficiency excitation energy transfer in laser-driven nanostructure systems

    NASA Astrophysics Data System (ADS)

    Weeraddana, Dilusha; Premaratne, Malin; Gunapala, Sarath D.; Andrews, David L.

    2016-08-01

    A fundamental theory is developed for describing laser-driven resonance energy transfer (RET) in dimensionally constrained nanostructures within the framework of quantum electrodynamics. The process of RET communicates electronic excitation between suitably disposed emitter and detector particles in close proximity, activated by the initial excitation of the emitter. Here, we demonstrate that the transfer rate can be significantly increased by propagation of an auxiliary laser beam through a pair of nanostructure particles. This is due to the higher order perturbative contribution to the Förster-type RET, in which laser field is applied to stimulate the energy transfer process. We construct a detailed picture of how excitation energy transfer is affected by an off-resonant radiation field, which includes the derivation of second and fourth order quantum amplitudes. The analysis delivers detailed results for the dependence of the transfer rates on orientational, distance, and laser intensity factor, providing a comprehensive fundamental understanding of laser-driven RET in nanostructures. The results of the derivations demonstrate that the geometry of the system exercises considerable control over the laser-assisted RET mechanism. Thus, under favorable conformational conditions and relative spacing of donor-acceptor nanostructures, the effect of the auxiliary laser beam is shown to produce up to 70% enhancement in the energy migration rate. This degree of control allows optical switching applications to be identified.

  18. Early Detection of T cell Transfer-induced Autoimmune Colitis by In Vivo Imaging System

    PubMed Central

    Chen, Yu-Ling; Chen, Yi-Ting; Lo, Cheng-Feng; Hsieh, Ching-I; Chiu, Shang-Yi; Wu, Chang-Yen; Yeh, Yu-Shan; Hung, Shu-Hsuan; Cheng, Po-Hao; Su, Yu-Hsuan; Jiang, Si-Tse; Chin, Hsian-Jean; Su, Yu-Chia

    2016-01-01

    Inflammatory bowel disease is a chronic and progressive inflammatory intestinal disease that includes two major types, namely ulcerative colitis and Crohn’s disease (CD). CD is characterized by intestinal epithelial hyperplasia and inflammatory cell infiltration. Transfer of CD25−CD45RBhiCD4+ (naïve) T cells into immunodeficiency mice induces autoimmune colitis with pathological lesions similar to CD and loss of body weight 4 weeks after cell transfer. However, weight loss neither has sufficient sensitivity nor totally matches the pathological findings of CD. To establish an early and sensitive indicator of autoimmune colitis model, the transferred T cell-induced colitis mouse model was modified by transferring luciferase-expressing donor T cells and determining the colitis by in vivo imaging system (IVIS). Colitis was detected with IVIS 7–10 days before the onset of body weight loss and diarrhea. IVIS was also applied in the dexamethasone treatment trial, and was a more sensitive indicator than body weight changes. All IVIS signals were parallel to the pathological abnormalities of the gut and immunological analysis results. In summary, IVIS provides both sensitive and objective means to monitor the disease course of transferred T cell-induced CD and fulfills the 3Rs principle of humane care of laboratory animals. PMID:27762297

  19. Quantifying electron transfer reactions in biological systems: what interactions play the major role?

    NASA Astrophysics Data System (ADS)

    Sjulstok, Emil; Olsen, Jógvan Magnus Haugaard; Solov'Yov, Ilia A.

    2015-12-01

    Various biological processes involve the conversion of energy into forms that are usable for chemical transformations and are quantum mechanical in nature. Such processes involve light absorption, excited electronic states formation, excitation energy transfer, electrons and protons tunnelling which for example occur in photosynthesis, cellular respiration, DNA repair, and possibly magnetic field sensing. Quantum biology uses computation to model biological interactions in light of quantum mechanical effects and has primarily developed over the past decade as a result of convergence between quantum physics and biology. In this paper we consider electron transfer in biological processes, from a theoretical view-point; namely in terms of quantum mechanical and semi-classical models. We systematically characterize the interactions between the moving electron and its biological environment to deduce the driving force for the electron transfer reaction and to establish those interactions that play the major role in propelling the electron. The suggested approach is seen as a general recipe to treat electron transfer events in biological systems computationally, and we utilize it to describe specifically the electron transfer reactions in Arabidopsis thaliana cryptochrome-a signaling photoreceptor protein that became attractive recently due to its possible function as a biological magnetoreceptor.

  20. The heat recovery with heat transfer methods from solar photovoltaic systems

    NASA Astrophysics Data System (ADS)

    Özakın, A. N.; Karsli, S.; Kaya, F.; Güllüce, H.

    2016-04-01

    Although there are many fluctuations in energy prices, they seems like rising day by day. Thus energy recovery systems have increasingly trend. Photovoltaic systems converts solar radiation directly into electrical energy thanks to semiconductors. But due to the nature of semiconductors, whole of solar energy cannot turn into electrical energy and the remaining energy turns into waste heat. The aim of this research is evaluate this waste heat energy by air cooling system. So, the energy efficiency of the system will be increased using appropriate heat transfer technologies such as fin, turbulator etc.