Sample records for present analysis shows

  1. Using Toulmin analysis to analyse an instructor's proof presentation in abstract algebra

    NASA Astrophysics Data System (ADS)

    Fukawa-connelly, Timothy

    2014-01-01

    This paper provides a method for analysing undergraduate teaching of proof-based courses using Toulmin's model (1969) of argumentation. It presents a case study of one instructor's presentation of proofs. The analysis shows that the instructor presents different levels of detail in different proofs; thus, the students have an inconsistent set of written models for their work. Similarly, the analysis shows that the details the instructor says aloud differ from what she writes down. Although her verbal commentary provides additional detail and appears to have pedagogical value, for instance, by modelling thinking that supports proof writing, this value might be better realized if she were to change her teaching practices.

  2. Using Toulmin Analysis to Analyse an Instructor's Proof Presentation in Abstract Algebra

    ERIC Educational Resources Information Center

    Fukawa-Connelly, Timothy

    2014-01-01

    This paper provides a method for analysing undergraduate teaching of proof-based courses using Toulmin's model (1969) of argumentation. It presents a case study of one instructor's presentation of proofs. The analysis shows that the instructor presents different levels of detail in different proofs; thus, the students have an inconsistent set of…

  3. Dynamic Characteristics and Stability Analysis of Space Shuttle Main Engine Oxygen Pump

    NASA Technical Reports Server (NTRS)

    Gunter, Edgar J.; Branagan, Lyle

    1991-01-01

    The dynamic characteristics of the Space Shuttle high pressure oxygen pump are presented. Experimental data is presented to show the vibration spectrum and response under actual engine operation and also in spin pit testing for balancing. The oxygen pump appears to be operating near a second critical speed and is sensitive to self excited aerodynamic cross coupling forces in the turbine and pump. An analysis is presented to show the improvement in pump stability by the application of turbulent flow seals, preburner seals, and pump shaft cross sectional modifications.

  4. Study of target and non-target interplay in spatial attention task.

    PubMed

    Sweeti; Joshi, Deepak; Panigrahi, B K; Anand, Sneh; Santhosh, Jayasree

    2018-02-01

    Selective visual attention is the ability to selectively pay attention to the targets while inhibiting the distractors. This paper aims to study the targets and non-targets interplay in spatial attention task while subject attends to the target object present in one visual hemifield and ignores the distractor present in another visual hemifield. This paper performs the averaged evoked response potential (ERP) analysis and time-frequency analysis. ERP analysis agrees to the left hemisphere superiority over late potentials for the targets present in right visual hemifield. Time-frequency analysis performed suggests two parameters i.e. event-related spectral perturbation (ERSP) and inter-trial coherence (ITC). These parameters show the same properties for the target present in either of the visual hemifields but show the difference while comparing the activity corresponding to the targets and non-targets. In this way, this study helps to visualise the difference between targets present in the left and right visual hemifields and, also the targets and non-targets present in the left and right visual hemifields. These results could be utilised to monitor subjects' performance in brain-computer interface (BCI) and neurorehabilitation.

  5. Analysis and design of high-power and efficient, millimeter-wave power amplifier systems using zero degree combiners

    NASA Astrophysics Data System (ADS)

    Tai, Wei; Abbasi, Mortez; Ricketts, David S.

    2018-01-01

    We present the analysis and design of high-power millimetre-wave power amplifier (PA) systems using zero-degree combiners (ZDCs). The methodology presented optimises the PA device sizing and the number of combined unit PAs based on device load pull simulations, driver power consumption analysis and loss analysis of the ZDC. Our analysis shows that an optimal number of N-way combined unit PAs leads to the highest power-added efficiency (PAE) for a given output power. To illustrate our design methodology, we designed a 1-W PA system at 45 GHz using a 45 nm silicon-on-insulator process and showed that an 8-way combined PA has the highest PAE that yields simulated output power of 30.6 dBm and 31% peak PAE.

  6. Solar and Climate Variation Relationships Analyzed from Chile Tree Ring Width Time Series (1587 - 1994 A.D.)

    NASA Astrophysics Data System (ADS)

    Rigozo, Nr; Nordemann, Djr; Faria, Hh; Echer, E.; Vieira, Lea; Prestes, A.

    This work presents a study of the relations between solar and climate variations during the last four centuries by spectral analysis of tree ring index and sunspot number time series. Trees used for this study were Pilgerodendron cupressoides from Glaciar Pio XI, in Chile. The spectral analysis of tree ring index shows that 11, 22 and 80 year periodicities of the solar cycle were present in this tree ring data with 0.95 confidence level. This result suggests a solar modulation of climate variations, as recorded by the tree ring growth. Short-term variations, between 2 - 7 years, are also present in tree ring data. Therefore spectral analysis clearly shows that both, solar and climate factors, are recorded in the tree ring data.

  7. Cost-volume-profit and net present value analysis of health information systems.

    PubMed

    McLean, R A

    1998-08-01

    The adoption of any information system should be justified by an economic analysis demonstrating that its projected benefits outweigh its projected costs. Analysis differ, however, on which methods to employ for such a justification. Accountants prefer cost-volume-profit analysis, and economists prefer net present value analysis. The article explains the strengths and weaknesses of each method and shows how they can be used together so that well-informed investments in information systems can be made.

  8. H2@Scale Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ruth, Mark

    2017-07-12

    'H2@Scale' is a concept based on the opportunity for hydrogen to act as an intermediate between energy sources and uses. Hydrogen has the potential to be used like the primary intermediate in use today, electricity, because it too is fungible. This presentation summarizes the H2@Scale analysis efforts performed during the first third of 2017. Results of technical potential uses and supply options are summarized and show that the technical potential demand for hydrogen is 60 million metric tons per year and that the U.S. has sufficient domestic resources to meet that demand. A high level infrastructure analysis is also presentedmore » that shows an 85% increase in energy on the grid if all hydrogen is produced from grid electricity. However, a preliminary spatial assessment shows that supply is sufficient in most counties across the U.S. The presentation also shows plans for analysis of the economic potential for the H2@Scale concept. Those plans involve developing supply and demand curves for potential hydrogen generation options and as compared to other options for use of that hydrogen.« less

  9. Show the Data, Don't Conceal Them

    ERIC Educational Resources Information Center

    Drummond, Gordon B.; Vowler, Sarah L.

    2011-01-01

    Current standards of data presentation and analysis in biological journals often fall short of ideal. This is the first of a planned series of short articles, to be published in a number of journals, aiming to highlight the principles of clear data presentation and appropriate statistical analysis. This article considers the methods used to show…

  10. Categorical Data Analysis Using a Skewed Weibull Regression Model

    NASA Astrophysics Data System (ADS)

    Caron, Renault; Sinha, Debajyoti; Dey, Dipak; Polpo, Adriano

    2018-03-01

    In this paper, we present a Weibull link (skewed) model for categorical response data arising from binomial as well as multinomial model. We show that, for such types of categorical data, the most commonly used models (logit, probit and complementary log-log) can be obtained as limiting cases. We further compare the proposed model with some other asymmetrical models. The Bayesian as well as frequentist estimation procedures for binomial and multinomial data responses are presented in details. The analysis of two data sets to show the efficiency of the proposed model is performed.

  11. Dynamical systems analysis of phantom dark energy models

    NASA Astrophysics Data System (ADS)

    Roy, Nandan; Bhadra, Nivedita

    2018-06-01

    In this work, we study the dynamical systems analysis of phantom dark energy models considering five different potentials. From the analysis of these five potentials we have found a general parametrization of the scalar field potentials which is obeyed by many other potentials. Our investigation shows that there is only one fixed point which could be the beginning of the universe. However, future destiny has many possible options. A detailed numerical analysis of the system has been presented. The observed late time behaviour in this analysis shows very good agreement with the recent observations.

  12. Presentation-Oriented Visualization Techniques.

    PubMed

    Kosara, Robert

    2016-01-01

    Data visualization research focuses on data exploration and analysis, yet the vast majority of visualizations people see were created for a different purpose: presentation. Whether we are talking about charts showing data to help make a presenter's point, data visuals created to accompany a news story, or the ubiquitous infographics, many more people consume charts than make them. Traditional visualization techniques treat presentation as an afterthought, but are there techniques uniquely suited to data presentation but not necessarily ideal for exploration and analysis? This article focuses on presentation-oriented techniques, considering their usefulness for presentation first and any other purposes as secondary.

  13. Symmetric functions and wavefunctions of XXZ-type six-vertex models and elliptic Felderhof models by Izergin-Korepin analysis

    NASA Astrophysics Data System (ADS)

    Motegi, Kohei

    2018-05-01

    We present a method to analyze the wavefunctions of six-vertex models by extending the Izergin-Korepin analysis originally developed for domain wall boundary partition functions. First, we apply the method to the case of the basic wavefunctions of the XXZ-type six-vertex model. By giving the Izergin-Korepin characterization of the wavefunctions, we show that these wavefunctions can be expressed as multiparameter deformations of the quantum group deformed Grothendieck polynomials. As a second example, we show that the Izergin-Korepin analysis is effective for analysis of the wavefunctions for a triangular boundary and present the explicit forms of the symmetric functions representing these wavefunctions. As a third example, we apply the method to the elliptic Felderhof model which is a face-type version and an elliptic extension of the trigonometric Felderhof model. We show that the wavefunctions can be expressed as one-parameter deformations of an elliptic analog of the Vandermonde determinant and elliptic symmetric functions.

  14. Automatic analysis of stereoscopic satellite image pairs for determination of cloud-top height and structure

    NASA Technical Reports Server (NTRS)

    Hasler, A. F.; Strong, J.; Woodward, R. H.; Pierce, H.

    1991-01-01

    Results are presented on an automatic stereo analysis of cloud-top heights from nearly simultaneous satellite image pairs from the GOES and NOAA satellites, using a massively parallel processor computer. Comparisons of computer-derived height fields and manually analyzed fields show that the automatic analysis technique shows promise for performing routine stereo analysis in a real-time environment, providing a useful forecasting tool by augmenting observational data sets of severe thunderstorms and hurricanes. Simulations using synthetic stereo data show that it is possible to automatically resolve small-scale features such as 4000-m-diam clouds to about 1500 m in the vertical.

  15. Is It Rational to Assume that Infants Imitate Rationally? A Theoretical Analysis and Critique

    ERIC Educational Resources Information Center

    Paulus, Markus

    2012-01-01

    It has been suggested that preverbal infants evaluate the efficiency of others' actions (by applying a "principle of rational action") and that they imitate others' actions rationally. The present contribution presents a conceptual analysis of the claim that preverbal infants imitate rationally. It shows that this ability rests on at least three…

  16. NASA TLA workload analysis support. Volume 3: FFD autopilot scenario validation data

    NASA Technical Reports Server (NTRS)

    Sundstrom, J. L.

    1980-01-01

    The data used to validate a seven time line analysis of forward flight deck autopilot mode for the pilot and copilot for NASA B737 terminal configured vehicle are presented. Demand workloads are given in two forms: workload histograms and workload summaries (bar graphs). A report showing task length and task interaction is also presented.

  17. Comprehensive and quantitative profiling of lipid species in human milk, cow milk and a phospholipid-enriched milk formula by GC and MS/MSALL.

    PubMed

    Sokol, Elena; Ulven, Trond; Færgeman, Nils J; Ejsing, Christer S

    2015-06-01

    Here we present a workflow for in-depth analysis of milk lipids that combines gas chromatography (GC) for fatty acid (FA) profiling and a shotgun lipidomics routine termed MS/MS ALL for structural characterization of molecular lipid species. To evaluate the performance of the workflow we performed a comparative lipid analysis of human milk, cow milk, and Lacprodan® PL-20, a phospholipid-enriched milk protein concentrate for infant formula. The GC analysis showed that human milk and Lacprodan have a similar FA profile with higher levels of unsaturated FAs as compared to cow milk. In-depth lipidomic analysis by MS/MS ALL revealed that each type of milk sample comprised distinct composition of molecular lipid species. Lipid class composition showed that the human and cow milk contain a higher proportion of triacylglycerols (TAGs) as compared to Lacprodan. Notably, the MS/MS ALL analysis demonstrated that the similar FA profile of human milk and Lacprodan determined by GC analysis is attributed to the composition of individual TAG species in human milk and glycerophospholipid species in Lacprodan. Moreover, the analysis of TAG molecules in Lacprodan and cow milk showed a high proportion of short-chain FAs that could not be monitored by GC analysis. The results presented here show that complementary GC and MS/MS ALL analysis is a powerful approach for characterization of molecular lipid species in milk and milk products. : Milk lipid analysis is routinely performed using gas chromatography. This method reports the total fatty acid composition of all milk lipids, but provides no structural or quantitative information about individual lipid molecules in milk or milk products. Here we present a workflow that integrates gas chromatography for fatty acid profiling and a shotgun lipidomics routine termed MS/MS ALL for structural analysis and quantification of molecular lipid species. We demonstrate the efficacy of this complementary workflow by a comparative analysis of molecular lipid species in human milk, cow milk, and a milk-based supplement used for infant formula.

  18. Comprehensive and quantitative profiling of lipid species in human milk, cow milk and a phospholipid-enriched milk formula by GC and MS/MSALL

    PubMed Central

    Sokol, Elena; Ulven, Trond; Færgeman, Nils J; Ejsing, Christer S

    2015-01-01

    Here we present a workflow for in-depth analysis of milk lipids that combines gas chromatography (GC) for fatty acid (FA) profiling and a shotgun lipidomics routine termed MS/MSALL for structural characterization of molecular lipid species. To evaluate the performance of the workflow we performed a comparative lipid analysis of human milk, cow milk, and Lacprodan® PL-20, a phospholipid-enriched milk protein concentrate for infant formula. The GC analysis showed that human milk and Lacprodan have a similar FA profile with higher levels of unsaturated FAs as compared to cow milk. In-depth lipidomic analysis by MS/MSALL revealed that each type of milk sample comprised distinct composition of molecular lipid species. Lipid class composition showed that the human and cow milk contain a higher proportion of triacylglycerols (TAGs) as compared to Lacprodan. Notably, the MS/MSALL analysis demonstrated that the similar FA profile of human milk and Lacprodan determined by GC analysis is attributed to the composition of individual TAG species in human milk and glycerophospholipid species in Lacprodan. Moreover, the analysis of TAG molecules in Lacprodan and cow milk showed a high proportion of short-chain FAs that could not be monitored by GC analysis. The results presented here show that complementary GC and MS/MSALL analysis is a powerful approach for characterization of molecular lipid species in milk and milk products. Practical applications : Milk lipid analysis is routinely performed using gas chromatography. This method reports the total fatty acid composition of all milk lipids, but provides no structural or quantitative information about individual lipid molecules in milk or milk products. Here we present a workflow that integrates gas chromatography for fatty acid profiling and a shotgun lipidomics routine termed MS/MSALL for structural analysis and quantification of molecular lipid species. We demonstrate the efficacy of this complementary workflow by a comparative analysis of molecular lipid species in human milk, cow milk, and a milk-based supplement used for infant formula. PMID:26089741

  19. Toxicological evaluation in silico and in vivo of secondary metabolites of Cissampelos sympodialis in Mus musculus mice following inhalation.

    PubMed

    Alves, Mateus Feitosa; Ferreira, Larissa Adilis Maria Paiva; Gadelha, Francisco Allysson Assis Ferreira; Ferreira, Laércia Karla Diega Paiva; Felix, Mayara Barbalho; Scotti, Marcus Tullius; Scotti, Luciana; de Oliveira, Kardilândia Mendes; Dos Santos, Sócrates Golzio; Diniz, Margareth de Fátima Formiga Melo

    2017-12-04

    The ethanolic extract of the leaves of Cissampelos sympodialis showed great pharmacological potential, with inflammatory and immunomodulatory activities, however, it showed some toxicological effects. Therefore, this study aims to verify the toxicological potential of alkaloids of the genus Cissampelos through in silico methodologies, to develop a method in LC-MS/MS verifying the presence of alkaloids in the infusion and to evaluate the toxicity of the infusion of the leaves of C. sympodialis when inhaled by Swiss mice. Results in silico showed that alkaloid 93 presented high toxicological potential along with the products of its metabolism. LC-MS/MS results showed that the infusion of the leaves of this plant contained the alkaloids warifteine and methylwarifteine. Finally, the in vivo toxicological analysis of the C. sympodialis infusion showed results, both in biochemistry, organ weights and histological analysis, that the infusion of C. sympodialis leaves presents a low toxicity.

  20. 48 CFR 217.170 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... contract to the cost of an annual procurement approach, using a present value analysis. Do not award the multiyear contract unless the analysis shows that the multiyear contract will result in the lower cost (10 U...

  1. Analysis of unmitigated large break loss of coolant accidents using MELCOR code

    NASA Astrophysics Data System (ADS)

    Pescarini, M.; Mascari, F.; Mostacci, D.; De Rosa, F.; Lombardo, C.; Giannetti, F.

    2017-11-01

    In the framework of severe accident research activity developed by ENEA, a MELCOR nodalization of a generic Pressurized Water Reactor of 900 MWe has been developed. The aim of this paper is to present the analysis of MELCOR code calculations concerning two independent unmitigated large break loss of coolant accident transients, occurring in the cited type of reactor. In particular, the analysis and comparison between the transients initiated by an unmitigated double-ended cold leg rupture and an unmitigated double-ended hot leg rupture in the loop 1 of the primary cooling system is presented herein. This activity has been performed focusing specifically on the in-vessel phenomenology that characterizes this kind of accidents. The analysis of the thermal-hydraulic transient phenomena and the core degradation phenomena is therefore here presented. The analysis of the calculated data shows the capability of the code to reproduce the phenomena typical of these transients and permits their phenomenological study. A first sequence of main events is here presented and shows that the cold leg break transient results faster than the hot leg break transient because of the position of the break. Further analyses are in progress to quantitatively assess the results of the code nodalization for accident management strategy definition and fission product source term evaluation.

  2. Analysis on the inbound tourist source market in Jiangxi based on geographic concentration index and market competition status

    NASA Astrophysics Data System (ADS)

    Yu, Tong; Ye, Yue-li

    2018-05-01

    In accordance with the related data of Statistical Yearbook of Jiangxi (2007—2016), conduct analysis on the development situation of inbound tourist source market in Jiangxi based on geographic concentration index and market competition status. The result shows: when the geographic concentration index of the inbound tourism market in Jiangxi presents an increasing decline trend, the tourism-generating countries of the inbound tourism in Jiangxi are getting more and more disperse, the tourist markets present the diversified feature and the inbound tourism market tends to be stable; besides, the analysis result of the market competition status shows that the inbound tourism development in Jiangxi has transformed from the rapid development to stable development.

  3. Some applications of categorical data analysis to epidemiological studies.

    PubMed Central

    Grizzle, J E; Koch, G G

    1979-01-01

    Several examples of categorized data from epidemiological studies are analyzed to illustrate that more informative analysis than tests of independence can be performed by fitting models. All of the analyses fit into a unified conceptual framework that can be performed by weighted least squares. The methods presented show how to calculate point estimate of parameters, asymptotic variances, and asymptotically valid chi 2 tests. The examples presented are analysis of relative risks estimated from several 2 x 2 tables, analysis of selected features of life tables, construction of synthetic life tables from cross-sectional studies, and analysis of dose-response curves. PMID:540590

  4. Analytics For Distracted Driver Behavior Modeling in Dilemma Zone

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Jan-Mou; Malikopoulos, Andreas; Thakur, Gautam

    2014-01-01

    In this paper, we present the results obtained and insights gained through the analysis of TRB contest data. We used exploratory analysis, regression, and clustering models for gaining insights into the driver behavior in a dilemma zone while driving under distraction. While simple exploratory analysis showed the distinguishing driver behavior patterns among different popu- lation groups in the dilemma zone, regression analysis showed statically signification relationships between groups of variables. In addition to analyzing the contest data, we have also looked into the possible impact of distracted driving on the fuel economy.

  5. Test 6, Test 7, and Gas Standard Analysis Results

    NASA Technical Reports Server (NTRS)

    Perez, Horacio, III

    2007-01-01

    This viewgraph presentation shows results of analyses on odor, toxic off gassing and gas standards. The topics include: 1) Statistical Analysis Definitions; 2) Odor Analysis Results NASA Standard 6001 Test 6; 3) Toxic Off gassing Analysis Results NASA Standard 6001 Test 7; and 4) Gas Standard Results NASA Standard 6001 Test 7;

  6. The Interaction between Multimedia Data Analysis and Theory Development in Design Research

    ERIC Educational Resources Information Center

    van Nes, Fenna; Doorman, Michiel

    2010-01-01

    Mathematics education researchers conducting instruction experiments using a design research methodology are challenged with the analysis of often complex and large amounts of qualitative data. In this paper, we present two case studies that show how multimedia analysis software can greatly support video data analysis and theory development in…

  7. Making the Hubble Space Telescope servicing mission safe

    NASA Technical Reports Server (NTRS)

    Bahr, N. J.; Depalo, S. V.

    1992-01-01

    The implementation of the HST system safety program is detailed. Numerous safety analyses are conducted through various phases of design, test, and fabrication, and results are presented to NASA management for discussion during dedicated safety reviews. Attention is given to the system safety assessment and risk analysis methodologies used, i.e., hazard analysis, fault tree analysis, and failure modes and effects analysis, and to how they are coupled with engineering and test analysis for a 'synergistic picture' of the system. Some preliminary safety analysis results, showing the relationship between hazard identification, control or abatement, and finally control verification, are presented as examples of this safety process.

  8. Invitation to Consumer Behavior Analysis

    ERIC Educational Resources Information Center

    Foxall, Gordon R.

    2010-01-01

    This article presents an introduction to consumer behavior analysis by describing the Behavioral Perspective Model of consumer choice and showing how research has, first, confirmed this framework and, second, opened up behavior analysis and behavioral economics to the study of consumer behavior in natural settings. It concludes with a discussion…

  9. Aerodynamic Performance of Missile Configurations at Transonic Speeds Including the Effects of a Jet Plume

    DTIC Science & Technology

    1976-02-18

    shows three different body-fixed Cartesian coordinate systems used in the present analysis . The Cartesian coordinate system with the axes x, y, and z... using the analysis of the previous section. A different situation exists when the base pressure is greater than the ambient value. Now it becomes... USED IN THE PRESENT ANALYSIS Figure 26. Computational model used in Section!!. D. 85 FIN BODY 00 C> Z t t Voa (b) FLOW FOR V oa z

  10. The application of digital techniques to the analysis of metallurgical experiments

    NASA Technical Reports Server (NTRS)

    Rathz, T. J.

    1977-01-01

    The application of a specific digital computer system (known as the Image Data Processing System) to the analysis of three NASA-sponsored metallurgical experiments is discussed in some detail. The basic hardware and software components of the Image Data Processing System are presented. Many figures are presented in the discussion of each experimental analysis in an attempt to show the accuracy and speed that the Image Data Processing System affords in analyzing photographic images dealing with metallurgy, and in particular with material processing.

  11. Classification of breast tissue in mammograms using efficient coding.

    PubMed

    Costa, Daniel D; Campos, Lúcio F; Barros, Allan K

    2011-06-24

    Female breast cancer is the major cause of death by cancer in western countries. Efforts in Computer Vision have been made in order to improve the diagnostic accuracy by radiologists. Some methods of lesion diagnosis in mammogram images were developed based in the technique of principal component analysis which has been used in efficient coding of signals and 2D Gabor wavelets used for computer vision applications and modeling biological vision. In this work, we present a methodology that uses efficient coding along with linear discriminant analysis to distinguish between mass and non-mass from 5090 region of interest from mammograms. The results show that the best rates of success reached with Gabor wavelets and principal component analysis were 85.28% and 87.28%, respectively. In comparison, the model of efficient coding presented here reached up to 90.07%. Altogether, the results presented demonstrate that independent component analysis performed successfully the efficient coding in order to discriminate mass from non-mass tissues. In addition, we have observed that LDA with ICA bases showed high predictive performance for some datasets and thus provide significant support for a more detailed clinical investigation.

  12. Analysis and Design of Power Factor Pre-Regulator Based on a Symmetrical Charge Pump Circuit Applied to Electronic Ballast

    NASA Astrophysics Data System (ADS)

    Lazcano Olea, Miguel; Ramos Astudillo, Reynaldo; Sanhueza Robles, René; Rodriguez Rubke, Leopoldo; Ruiz-Caballero, Domingo Antonio

    This paper presents the analysis and design of a power factor pre-regulator based on a symmetrical charge pump circuit applied to electronic ballast. The operation stages of the circuit are analyzed and its main design equations are obtained. Simulation and experimental results are presented in order to show the design methodology feasibility.

  13. Numerical Analysis of Intra-Cavity and Power-Stream Flow Interaction in Multiple Gas-Turbine Disk-Cavities

    NASA Technical Reports Server (NTRS)

    Athavale, M. M.; Przekwas, A. J.; Hendricks, R. C.; Steinetz, B. M.

    1995-01-01

    A numerical analysis methodology and solutions of the interaction between the power stream and multiply-connected multi-cavity sealed secondary flow fields are presented. Flow solutions for a multi-cavity experimental rig were computed and compared with experimental data of Daniels and Johnson. The flow solutions illustrate the complex coupling between the main-path and the cavity flows as well as outline the flow thread that exists throughout the subplatform multiple cavities and seals. The analysis also shows that the de-coupled solutions on single cavities is inadequate. The present results show trends similar to the T-700 engine data that suggests the changes in the CDP seal altered the flow fields throughout the engine and affected the engine performance.

  14. In situ visualization and data analysis for turbidity currents simulation

    NASA Astrophysics Data System (ADS)

    Camata, Jose J.; Silva, Vítor; Valduriez, Patrick; Mattoso, Marta; Coutinho, Alvaro L. G. A.

    2018-01-01

    Turbidity currents are underflows responsible for sediment deposits that generate geological formations of interest for the oil and gas industry. LibMesh-sedimentation is an application built upon the libMesh library to simulate turbidity currents. In this work, we present the integration of libMesh-sedimentation with in situ visualization and in transit data analysis tools. DfAnalyzer is a solution based on provenance data to extract and relate strategic simulation data in transit from multiple data for online queries. We integrate libMesh-sedimentation and ParaView Catalyst to perform in situ data analysis and visualization. We present a parallel performance analysis for two turbidity currents simulations showing that the overhead for both in situ visualization and in transit data analysis is negligible. We show that our tools enable monitoring the sediments appearance at runtime and steer the simulation based on the solver convergence and visual information on the sediment deposits, thus enhancing the analytical power of turbidity currents simulations.

  15. Structural dynamics of shroudless, hollow fan blades with composite in-lays

    NASA Technical Reports Server (NTRS)

    Aiello, R. A.; Hirschbein, M. S.; Chamis, C. C.

    1982-01-01

    Structural and dynamic analyses are presented for a shroudless, hollow titanium fan blade proposed for future use in aircraft turbine engines. The blade was modeled and analyzed using the composite blade structural analysis computer program (COBSTRAN); an integrated program consisting of mesh generators, composite mechanics codes, NASTRAN, and pre- and post-processors. Vibration and impact analyses are presented. The vibration analysis was conducted with COBSTRAN. Results show the effect of the centrifugal force field on frequencies, twist, and blade camber. Bird impact analysis was performed with the multi-mode blade impact computer program. This program uses the geometric model and modal analysis from the COBSTRAN vibration analysis to determine the gross impact response of the fan blades to bird strikes. The structural performance of this blade is also compared to a blade of similar design but with composite in-lays on the outer surface. Results show that the composite in-lays can be selected (designed) to substantially modify the mechanical performance of the shroudless, hollow fan blade.

  16. [Text Comprehensibility of Hospital Report Cards].

    PubMed

    Sander, U; Kolb, B; Christoph, C; Emmert, M

    2016-12-01

    Objectives: Recently, the number of hospital report cards that compare quality of hospitals and present information from German quality reports has greatly increased. Objectives of this study were to a) identify suitable methods for measuring the readability and comprehensibility of hospital report cards, b) to obtain reliable information on the comprehensibility of texts for laymen, c) to give recommendations for improvements and d) to recommend public health actions. Methods: The readability and comprehensibility of the texts were tested with a) a computer-aided evaluation of formal text characteristics (readability indices Flesch (German formula) and 1. Wiener Sachtextformel formula), b) an expert-based heuristic analysis of readability and comprehensibility of texts (counting technical terms and analysis of text simplicity as well as brevity and conciseness using the Hamburg intelligibility model) and c) a survey of subjects about the comprehensibility of individual technical terms, the assessment of the comprehensibility of the presentations and the subjects' decisions in favour of one of the 5 presented clinics due to the better quality of data. In addition, the correlation between the results of the text analysis with the results from the survey of subjects was tested. Results: The assessment of texts with the computer-aided evaluations showed poor comprehensibility values. The assessment of text simplicity using the Hamburg intelligibility model showed poor comprehensibility values (-0.3). On average, 6.8% of the words used were technical terms. A review of 10 technical terms revealed that in all cases only a minority of respondents (from 4.4% to 39.1%) exactly knew what was meant by each of them. Most subjects (62.4%) also believed that unclear terms worsened their understanding of the information offered. The correlation analysis showed that presentations with a lower frequency of technical terms and better values for the text simplicity were better understood. Conclusion: The determination of the frequency of technical terms and the assessment of text simplicity using the Hamburg intelligibility model were suitable methods to determine the readability and comprehensibility of presentations of quality indicators. The analysis showed predominantly poor comprehensibility values and indicated the need to improve the texts of report cards. © Georg Thieme Verlag KG Stuttgart · New York.

  17. A computer-aided movement analysis system.

    PubMed

    Fioretti, S; Leo, T; Pisani, E; Corradini, M L

    1990-08-01

    Interaction with biomechanical data concerning human movement analysis implies the adoption of various experimental equipments and the choice of suitable models, data processing, and graphical data restitution techniques. The integration of measurement setups with the associated experimental protocols and the relative software procedures constitutes a computer-aided movement analysis (CAMA) system. In the present paper such integration is mapped onto the causes that limit the clinical acceptance of movement analysis methods. The structure of the system is presented. A specific CAMA system devoted to posture analysis is described in order to show the attainable features. Scientific results obtained with the support of the described system are also reported.

  18. A quantitative analysis of the F18 flight control system

    NASA Technical Reports Server (NTRS)

    Doyle, Stacy A.; Dugan, Joanne B.; Patterson-Hine, Ann

    1993-01-01

    This paper presents an informal quantitative analysis of the F18 flight control system (FCS). The analysis technique combines a coverage model with a fault tree model. To demonstrate the method's extensive capabilities, we replace the fault tree with a digraph model of the F18 FCS, the only model available to us. The substitution shows that while digraphs have primarily been used for qualitative analysis, they can also be used for quantitative analysis. Based on our assumptions and the particular failure rates assigned to the F18 FCS components, we show that coverage does have a significant effect on the system's reliability and thus it is important to include coverage in the reliability analysis.

  19. Type airman certification as related to accidents.

    DOT National Transportation Integrated Search

    1967-10-01

    An analysis of 1964 aircraft accidents, using type of airman certificate as a measure of pilot proficiency, is presented. Data show that student pilots generally have a better accident record than any other of the certification groups. Analysis confi...

  20. Modern Era Retrospective-analysis for Research and Applications (MERRA) Global Water and Energy Budgets

    NASA Technical Reports Server (NTRS)

    Bosilovich, Michael G.; Robertson, Franklin R.; Chen, Junye

    2008-01-01

    The Modern. Era Retrospective-analysis for Research and Applications (MERRA) reanalyses has produced several years of data, on the way to a completing. the 1979-present modern satellite era. Here, we present a preliminary evaluation of those years currently available, includin g comparisons with the existing long reanalyses (ERA40, JRA25 and NCE P I and II) as well as with global data sets for the water and energy cycle Time series shows that the MERRA budgets can change with some of the variations in observing systems. We will present all terms of the budgets in MERRA including the time rates of change and analysis increments (tendency due to the analysis of observations)

  1. Static headspace analysis using polyurethane phases--application to roasted coffee volatiles characterization.

    PubMed

    Rodrigues, C; Portugal, F C M; Nogueira, J M F

    2012-01-30

    Static headspace sorptive extraction using polyurethane foams (HSSE(PU)) followed by gas chromatography coupled to mass spectrometry is proposed for volatile analysis. The application of this novel analytical approach to characterize the volatiles profile from roasted coffee samples, selected as model system, revealed remarkable advantages under convenient experimental conditions. The comparison of HSSE(PU) with other well-established procedures, such as headspace sorptive extraction using polydimethylsiloxane (HSSE(PDMS)) and headspace solid phase microextraction using carboxen/polydimethylsiloxane fibers (HS-SPME(CAR/PDMS)), showed that the former presented much higher capacity, sensitivity and even selectivity, where larger abundance and number of roasted coffee volatile compounds (e.g. furans, pyrazines, ketones, acids and pyrroles) could be achieved, under similar experimental conditions. The data presented herein proved, for the first time, that PU foams present great performance for static headspace sorption-based procedures, showing to be an alternative polymeric phase for volatile analysis. Copyright © 2011 Elsevier B.V. All rights reserved.

  2. An Analysis of Spacecraft Localization from Descent Image Data for Pinpoint Landing on Mars and other Cratered Bodies Data Acquisition

    NASA Technical Reports Server (NTRS)

    Ansar, Adnan; Cheng, Yang

    2005-01-01

    A pinpoint landing capability will be a critical component for many planned NASA missions to Mars and beyond. Implicit in the requirement is the ability to accurately localize the spacecraft with respect to the terrain during descent. In this paper, we present evidence that a vision-based solution using craters as landmarks is both practical and will meet the requirements of next generation missions. Our emphasis in this paper is on the feasibility of such a system in terms of (a) localization accuracy and (b) applicability to Martian terrain. We show that accuracy of well under 100 meters can be expected under suitable conditions. We also present a sensitivity analysis that makes an explicit connection between input data and robustness of our pose estimate. In addition, we present an analysis of the susceptibility of our technique to inherently ambiguous configurations of craters. We show that probability of failure due to such ambiguity is becoming increasingly small.

  3. Doppler Global Velocimeter Development for the Large Wind Tunnels at Ames Research Center

    NASA Technical Reports Server (NTRS)

    Reinath, Michael S.

    1997-01-01

    Development of an optical, laser-based flow-field measurement technique for large wind tunnels is described. The technique uses laser sheet illumination and charged coupled device detectors to rapidly measure flow-field velocity distributions over large planar regions of the flow. Sample measurements are presented that illustrate the capability of the technique. An analysis of measurement uncertainty, which focuses on the random component of uncertainty, shows that precision uncertainty is not dependent on the measured velocity magnitude. For a single-image measurement, the analysis predicts a precision uncertainty of +/-5 m/s. When multiple images are averaged, this uncertainty is shown to decrease. For an average of 100 images, for example, the analysis shows that a precision uncertainty of +/-0.5 m/s can be expected. Sample applications show that vectors aligned with an orthogonal coordinate system are difficult to measure directly. An algebraic transformation is presented which converts measured vectors to the desired orthogonal components. Uncertainty propagation is then used to show how the uncertainty propagates from the direct measurements to the orthogonal components. For a typical forward-scatter viewing geometry, the propagation analysis predicts precision uncertainties of +/-4, +/-7, and +/-6 m/s, respectively, for the U, V, and W components at 68% confidence.

  4. Molecular characterization of total and metabolically active bacterial communities of "white colonizations" in the Altamira Cave, Spain.

    PubMed

    Portillo, M Carmen; Saiz-Jimenez, Cesareo; Gonzalez, Juan M

    2009-01-01

    Caves with paleolithic paintings are influenced by bacterial development. Altamira Cave (Spain) contains some of the most famous paintings from the Paleolithic era. An assessment of the composition of bacterial communities that have colonized this cave represents a first step in understanding and potentially controlling their proliferation. In this study, areas showing colonization with uncolored microorganisms, referred to as "white colonizations", were analyzed. Microorganisms present in these colonizations were studied using DNA analysis, and those showing significant metabolic activity were detected in RNA-based RNA analysis. Bacterial community fingerprints were obtained both from DNA and RNA analyses, indicating differences between the microorganisms present and metabolically active in these white colonizations. Metabolically active microorganisms represented only a fraction of the total bacterial community present in the colonizations. 16S rRNA gene libraries were used to identify the major representative members of the studied communities. Proteobacteria constituted the most frequently found division both among metabolically active microorganisms (from RNA-based analysis) and those present in the community (from DNA analysis). Results suggest the existence of a huge variety of taxa in white colonizations of the Altamira Cave which represent a potential risk for the conservation of the cave and its paintings.

  5. Molecular evidence for a single taxon, Anopheles nuneztovari s. l., from two endemic malaria regions in Colombia

    PubMed Central

    Jaramillo, Luz Marina; Gutiérrez, Lina A; Luckhart, Shirley; Conn, Jan E; Correa, Margarita M

    2012-01-01

    To elucidate the Anopheles nuneztovari s.l. taxonomic status at a microgeographic level in four malaria endemic localities from Antioquia and Córdoba, Colombia, fragments of the Cytochrome oxidase subunit I (COI) and the white gene were used. The COI analysis showed low genetic differentiation with FST levels between −0.02 and 0.137 and Nm values between 3 and infinity, indicating the presence of high gene flow among An. nuneztovari s.l. populations from the four localities. The COI network showed a single most common haplotype, 1 (n=55), present in all localities, as the likely ancestral haplotype. Analysis of the white gene showed that An. nuneztovari s.l. populations from both departments grouped with haplotypes 19 and 20, which are part of lineage 3 previously reported. The results of the present study suggest that An. nuneztovari s.l. is a single taxon in the area of the present study. PMID:22241127

  6. Spatial Dependence and Heterogeneity in Bayesian Factor Analysis: A Cross-National Investigation of Schwartz Values

    ERIC Educational Resources Information Center

    Stakhovych, Stanislav; Bijmolt, Tammo H. A.; Wedel, Michel

    2012-01-01

    In this article, we present a Bayesian spatial factor analysis model. We extend previous work on confirmatory factor analysis by including geographically distributed latent variables and accounting for heterogeneity and spatial autocorrelation. The simulation study shows excellent recovery of the model parameters and demonstrates the consequences…

  7. Network Analysis of a Demonstration Program for the Developmentally Disabled

    ERIC Educational Resources Information Center

    Fredericks, Kimberly A.

    2005-01-01

    This chapter presents the findings from a network analysis of a demonstration program for the developmentally disabled to show the application of graphical network analysis in program evaluation. The developmentally disabled demonstration (DDD) program was a five-year pilot project to provide person-centered service environments to people with …

  8. Orbital transfer rocket engine technology 7.5K-LB thrust rocket engine preliminary design

    NASA Technical Reports Server (NTRS)

    Harmon, T. J.; Roschak, E.

    1993-01-01

    A preliminary design of an advanced LOX/LH2 expander cycle rocket engine producing 7,500 lbf thrust for Orbital Transfer vehicle missions was completed. Engine system, component and turbomachinery analysis at both on design and off design conditions were completed. The preliminary design analysis results showed engine requirements and performance goals were met. Computer models are described and model outputs are presented. Engine system assembly layouts, component layouts and valve and control system analysis are presented. Major design technologies were identified and remaining issues and concerns were listed.

  9. High-Throughput Method for Strontium Isotope Analysis by Multi-Collector-Inductively Coupled Plasma-Mass Spectrometer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wall, Andrew J.; Capo, Rosemary C.; Stewart, Brian W.

    2016-09-22

    This technical report presents the details of the Sr column configuration and the high-throughput Sr separation protocol. Data showing the performance of the method as well as the best practices for optimizing Sr isotope analysis by MC-ICP-MS is presented. Lastly, this report offers tools for data handling and data reduction of Sr isotope results from the Thermo Scientific Neptune software to assist in data quality assurance, which help avoid issues of data glut associated with high sample throughput rapid analysis.

  10. High-Throughput Method for Strontium Isotope Analysis by Multi-Collector-Inductively Coupled Plasma-Mass Spectrometer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hakala, Jacqueline Alexandra

    2016-11-22

    This technical report presents the details of the Sr column configuration and the high-throughput Sr separation protocol. Data showing the performance of the method as well as the best practices for optimizing Sr isotope analysis by MC-ICP-MS is presented. Lastly, this report offers tools for data handling and data reduction of Sr isotope results from the Thermo Scientific Neptune software to assist in data quality assurance, which help avoid issues of data glut associated with high sample throughput rapid analysis.

  11. NASA Environmentally Responsible Aviation's Highly-Loaded Front Block Compressor Demonstration

    NASA Technical Reports Server (NTRS)

    Celestina, Mark

    2016-01-01

    This presentation will detail the work done to improve thermal efficiency in the compression process of a gas turbine engine for aircraft applications under NASAs Environmentally Responsible Aviation Project. The talk will present the goals and objectives of the work and show the activity of both Phase 1 and Phase 2 tests and analysis. The summary shows the projected fuel burn savings achieved through system studies.

  12. Aerodynamic design of a rotor blade for minimum noise radiation

    NASA Technical Reports Server (NTRS)

    Karamcheti, K.; Yu, Y. H.

    1974-01-01

    An analysis of the aerodynamic design of a hovering rotor blade for obtaining minimum aerodynamic rotor noise has been carried out. In this analysis, which is based on both acoustical and aerodynamic considerations, attention is given only to the rotational noise due to the pressure fluctuations on the blade surfaces. The lift distribution obtained in this analysis has different characteristics from those of the conventional distribution. The present distribution shows negative lift values over a quarter of the span from the blade tip, and a maximum lift at about the midspan. Results are presented to show that the noise field is considerably affected by the shape of the lift distribution along the blade and that noise reduction of about 5 dB may be obtained by designing the rotor blade to yield minimum noise.

  13. Substantiation Data for Advanced Beaded and Tubular Structural Panels. Volume 3: Testing

    NASA Technical Reports Server (NTRS)

    Hedges, P. C.; Greene, B. E.

    1974-01-01

    The test program is described, which was conducted to provide the necessary experimental data to verify the design and analysis methods developed for beaded and tubular panels. Test results are summarized and presented for all local buckling and full size panel tests. Selected representative test data from each of these tests is presented in detail. The results of this program established a valid analysis and design procedure for circular tube panels. Test results from three other configurations show deformational modes which are not adequately accounted for in the present analyses.

  14. Dynamic fuzzy hierarchy analysis for evaluation of professionalization degree

    NASA Astrophysics Data System (ADS)

    Jin, Lin; Min, Luo; Ma, Jingxi

    2016-06-01

    This paper presents the model of dynamic fuzzy hierarchy analysis for evaluation of professionalization degree, as a combination of the dynamic fuzzy theory and the AHP, which can show the changes and trends of the value of each index of professionalization.

  15. Structural and electronic properties of in-plane phase engineered WSe2: A DFT study

    NASA Astrophysics Data System (ADS)

    Bhart, Ankush; Kapoor, Pooja; Sharma, Munish; Sharma, Raman; Ahluwalia, P. K.

    2018-04-01

    We present first principal investigations on structural and electronic properties of in-plane phase engineered WSe2 with armchair type interface. The 2H and 1T phases of WSe2, joined along x-direction is a natural metal-semiconductor heterostructure and therefore shows potential for applications in 2D electronics and opto-electronics. The electronic properties transit towards metallic 1T region. No inflections across interface shows negligible mismatch strain which is unlike what has been reported for MoS2. Charge density analysis shows charge accumulation on 1T domain. This can lead to reduction of Schottky barrier heights at the metal-semiconductor junction. STM analysis confirms transition of 1T phase towards distorted 1T' structure. The present results provide essential insights for nano-devices using 2D hybrid materials.

  16. Evaluation of the Modern Era Retrospective-Analysis for Research and Applications (MERRA) Global Water and Energy Budgets

    NASA Technical Reports Server (NTRS)

    Bosilovich, Michael G.; Robertson, F. R.; Chen, J.

    2010-01-01

    The Modern Era Retrospective-analysis for Research and Applications (MERRA) reanalyses has completed 27 years of data) soon to be caught up to present. Here) we present an evaluation of those years currently available) including comparisons with the existing long reanalyses (ERA40) JRA25 and NCEP I and II) as well as with global data sets for the water and energy cycle. Time series shows that the MERRA budgets can change with some of the variations in observing systems, but that the magnitude of energy imbalance in the system is improved with more observations. We will present all terms of the budgets in MERRA including the time rates of change and analysis increments (tendency due to the analysis of observations).

  17. Paraconsistent Annotated Logic in Viability Analysis: an Approach to Product Launching

    NASA Astrophysics Data System (ADS)

    Romeu de Carvalho, Fábio; Brunstein, Israel; Abe, Jair Minoro

    2004-08-01

    In this paper we present an application of the Para-analyzer, a logical analyzer based on the Paraconsistent Annotated Logic Pτ, introduced by Da Silva Filho and Abe in the decision-making systems. An example is analyzed in detail showing how uncertainty, inconsistency and paracompleteness can be elegantly handled with this logical system. As application for the Para-analyzer in decision-making, we developed the BAM — Baricenter Analysis Method. In order to make the presentation easier, we present the BAM applied in the viability analysis of product launching. Some of the techniques of Paraconsistent Annotated Logic have been applied in Artificial Intelligence, Robotics, Information Technolgy (Computer Sciences), etc..

  18. Analysis of Neural Stem Cells from Human Cortical Brain Structures In Vitro.

    PubMed

    Aleksandrova, M A; Poltavtseva, R A; Marei, M V; Sukhikh, G T

    2016-05-01

    Comparative immunohistochemical analysis of the neocortex from human fetuses showed that neural stem and progenitor cells are present in the brain throughout the gestation period, at least from week 8 through 26. At the same time, neural stem cells from the first and second trimester fetuses differed by the distribution, morphology, growth, and quantity. Immunocytochemical analysis of neural stem cells derived from fetuses at different gestation terms and cultured under different conditions showed their differentiation capacity. Detailed analysis of neural stem cell populations derived from fetuses on gestation weeks 8-9, 18-20, and 26 expressing Lex/SSEA1 was performed.

  19. Integrated microfluidic chip for rapid DNA digestion and time-resolved capillary electrophoresis analysis

    PubMed Central

    Lin, Che-Hsin; Wang, Yao-Nan; Fu, Lung-Ming

    2012-01-01

    An integrated microfluidic chip is proposed for rapid DNA digestion and time-resolved capillary electrophoresis (CE) analysis. The chip comprises two gel-filled chambers for DNA enrichment and purification, respectively, a T-form micromixer for DNA/restriction enzyme mixing, a serpentine channel for DNA digestion reaction, and a CE channel for on-line capillary electrophoresis analysis. The DNA and restriction enzyme are mixed electroomostically using a pinched-switching DC field. The experimental and numerical results show that a mixing performance of 97% is achieved within a distance of 1 mm from the T-junction when a driving voltage of 90 V/cm and a switching frequency of 4 Hz are applied. Successive mixing digestion and capillary electrophoresis operation clearly present the changes on digesting φx-174 DNA in different CE runs. The time-resolved electropherograms show that the proposed device enables a φx-174 DNA sample comprising 11 fragments to be concentrated and analyzed within 24 min. Overall, the results presented in this study show that the proposed microfluidic chip provides a rapid and effective tool for DNA digestion and CE analysis applications. PMID:22662085

  20. Religious Education in Russia: A Comparative and Critical Analysis

    ERIC Educational Resources Information Center

    Blinkova, Alexandra; Vermeer, Paul

    2018-01-01

    RE in Russia has been recently introduced as a compulsory regular school subject during the last year of elementary school. The present study offers a critical analysis of the current practice of Russian RE by comparing it with RE in Sweden, Denmark and Britain. This analysis shows that Russian RE is ambivalent. Although it is based on a…

  1. Metallic content of wines from the Canary Islands (Spain). Application of artificial neural networks to the data analysis.

    PubMed

    Frías, Sergio; Conde, José E; Rodríguez, Miguel A; Dohnal, Vlasta; Pérez-Trujillo, Juan P

    2002-10-01

    Eleven elements, K, Na, Ca, Mg, Fe, Cu, Zn, Mn, Sr, Li and Rb, were determined in dry and sweet wines bearing the denominations of origin of El Hierro, La Palma and Lanzarote islands (Canary Islands, Spain). Analyses were performed by flame atomic absorption spectrophotometry, with the exceptions of Li and Rb for which flame atomic emission spectrophotometry was used. The content in copper and iron did not present risks of cases. All samples presented a copper and zinc content below the maximum amount recommended by the Office International de la Vigne et du Vin (OIV) for these elements. Significant differences in the metallic content were found among the different islands. Thus, Lanzarote presented the highest mean content in sodium and lithium and the lowest mean content in rubidium, and La Palma presented the highest mean content in strontium and rubidium. Sweet wines from La Palma, elaborated as naturally sweet with over-ripe grapes, presented mean contents significantly higher with regard to dry wines from the same island in the majority of the analysed elements. Cluster analysis and Kohonen self-organising maps showed differences in wines according to the island of origin and the ripening state of the grapes. Back-propagation artificial neural networks showed better prediction ability than stepwise linear discriminant analysis.

  2. Classification of functional interactions from multi-electrodes data using conditional modularity analysis

    NASA Astrophysics Data System (ADS)

    Makhtar, Siti Noormiza; Senik, Mohd Harizal

    2018-02-01

    The availability of massive amount of neuronal signals are attracting widespread interest in functional connectivity analysis. Functional interactions estimated by multivariate partial coherence analysis in the frequency domain represent the connectivity strength in this study. Modularity is a network measure for the detection of community structure in network analysis. The discovery of community structure for the functional neuronal network was implemented on multi-electrode array (MEA) signals recorded from hippocampal regions in isoflurane-anaesthetized Lister-hooded rats. The analysis is expected to show modularity changes before and after local unilateral kainic acid (KA)-induced epileptiform activity. The result is presented using color-coded graphic of conditional modularity measure for 19 MEA nodes. This network is separated into four sub-regions to show the community detection within each sub-region. The results show that classification of neuronal signals into the inter- and intra-modular nodes is feasible using conditional modularity analysis. Estimation of segregation properties using conditional modularity analysis may provide further information about functional connectivity from MEA data.

  3. Quantified Energy Dissipation Rates in the Terrestrial Bow Shock. 1.; Analysis Techniques and Methodology

    NASA Technical Reports Server (NTRS)

    Wilson, L. B., III; Sibeck, D. G.; Breneman, A.W.; Le Contel, O.; Cully, C.; Turner, D. L.; Angelopoulos, V.; Malaspina, D. M.

    2014-01-01

    We present a detailed outline and discussion of the analysis techniques used to compare the relevance of different energy dissipation mechanisms at collisionless shock waves. We show that the low-frequency, quasi-static fields contribute less to ohmic energy dissipation, (-j · E ) (minus current density times measured electric field), than their high-frequency counterparts. In fact, we found that high-frequency, large-amplitude (greater than 100 millivolts per meter and/or greater than 1 nanotesla) waves are ubiquitous in the transition region of collisionless shocks. We quantitatively show that their fields, through wave-particle interactions, cause enough energy dissipation to regulate the global structure of collisionless shocks. The purpose of this paper, part one of two, is to outline and describe in detail the background, analysis techniques, and theoretical motivation for our new results presented in the companion paper. The companion paper presents the results of our quantitative energy dissipation rate estimates and discusses the implications. Together, the two manuscripts present the first study quantifying the contribution that high-frequency waves provide, through wave-particle interactions, to the total energy dissipation budget of collisionless shock waves.

  4. High resolution melting analysis is a more sensitive and effective alternative to gel-based platforms in analysis of SSR--an example in citrus.

    PubMed

    Distefano, Gaetano; Caruso, Marco; La Malfa, Stefano; Gentile, Alessandra; Wu, Shu-Biao

    2012-01-01

    High resolution melting curve analysis (HRM) has been used as an efficient, accurate and cost-effective tool to detect single nucleotide polymorphisms (SNPs) or insertions or deletions (INDELs). However, its efficiency, accuracy and applicability to discriminate microsatellite polymorphism have not been extensively assessed. The traditional protocols used for SSR genotyping include PCR amplification of the DNA fragment and the separation of the fragments on electrophoresis-based platform. However, post-PCR handling processes are laborious and costly. Furthermore, SNPs present in the sequences flanking repeat motif cannot be detected by polyacrylamide-gel-electrophoresis based methods. In the present study, we compared the discriminating power of HRM with the traditional electrophoresis-based methods and provided a panel of primers for HRM genotyping in Citrus. The results showed that sixteen SSR markers produced distinct polymorphic melting curves among the Citrus spp investigated through HRM analysis. Among those, 10 showed more genotypes by HRM analysis than capillary electrophoresis owing to the presence of SNPs in the amplicons. For the SSR markers without SNPs present in the flanking region, HRM also gave distinct melting curves which detected same genotypes as were shown in capillary electrophoresis (CE) analysis. Moreover, HRM analysis allowed the discrimination of most of the 15 citrus genotypes and the resulting genetic distance analysis clustered them into three main branches. In conclusion, it has been approved that HRM is not only an efficient and cost-effective alternative of electrophoresis-based method for SSR markers, but also a method to uncover more polymorphisms contributed by SNPs present in SSRs. It was therefore suggested that the panel of SSR markers could be used in a variety of applications in the citrus biodiversity and breeding programs using HRM analysis. Furthermore, we speculate that the HRM analysis can be employed to analyse SSR markers in a wide range of applications in all other species.

  5. Vitality Forms Processing in the Insula during Action Observation: A Multivoxel Pattern Analysis

    PubMed Central

    Di Cesare, Giuseppe; Valente, Giancarlo; Di Dio, Cinzia; Ruffaldi, Emanuele; Bergamasco, Massimo; Goebel, Rainer; Rizzolatti, Giacomo

    2016-01-01

    Observing the style of an action done by others allows the observer to understand the cognitive state of the agent. This information has been defined by Stern “vitality forms”. Previous experiments showed that the dorso-central insula is selectively active both during vitality form observation and execution. In the present study, we presented participants with videos showing hand actions performed with different velocities and asked them to judge either their vitality form (gentle, neutral, rude) or their velocity (slow, medium, fast). The aim of the present study was to assess, using multi-voxel pattern analysis, whether vitality forms and velocities of observed goal-directed actions are differentially processed in the insula, and more specifically whether action velocity is encoded per se or it is an element that triggers neural populations of the insula encoding the vitality form. The results showed that, consistently across subjects, in the dorso-central sector of the insula there were voxels selectively tuned to vitality forms, while voxel tuned to velocity were rare. These results indicate that the dorso-central insula, which previous data showed to be involved in the vitality form processing, contains voxels specific for the action style processing. PMID:27375461

  6. Vitality Forms Processing in the Insula during Action Observation: A Multivoxel Pattern Analysis.

    PubMed

    Di Cesare, Giuseppe; Valente, Giancarlo; Di Dio, Cinzia; Ruffaldi, Emanuele; Bergamasco, Massimo; Goebel, Rainer; Rizzolatti, Giacomo

    2016-01-01

    Observing the style of an action done by others allows the observer to understand the cognitive state of the agent. This information has been defined by Stern "vitality forms". Previous experiments showed that the dorso-central insula is selectively active both during vitality form observation and execution. In the present study, we presented participants with videos showing hand actions performed with different velocities and asked them to judge either their vitality form (gentle, neutral, rude) or their velocity (slow, medium, fast). The aim of the present study was to assess, using multi-voxel pattern analysis, whether vitality forms and velocities of observed goal-directed actions are differentially processed in the insula, and more specifically whether action velocity is encoded per se or it is an element that triggers neural populations of the insula encoding the vitality form. The results showed that, consistently across subjects, in the dorso-central sector of the insula there were voxels selectively tuned to vitality forms, while voxel tuned to velocity were rare. These results indicate that the dorso-central insula, which previous data showed to be involved in the vitality form processing, contains voxels specific for the action style processing.

  7. Navicula sp. Sulfated Polysaccharide Gels Induced by Fe(III): Rheology and Microstructure

    PubMed Central

    Fimbres-Olivarría, Diana; López-Elías, José Antonio; Carvajal-Millán, Elizabeth; Márquez-Escalante, Jorge Alberto; Martínez-Córdova, Luis Rafael; Miranda-Baeza, Anselmo; Enríquez-Ocaña, Fernando; Valdéz-Holguín, José Eduardo; Brown-Bojórquez, Francisco

    2016-01-01

    A sulfated polysaccharide extracted from Navicula sp. presented a yield of 4.4 (% w/w dry biomass basis). Analysis of the polysaccharide using gas chromatography showed that this polysaccharide contained glucose (29%), galactose (21%), rhamnose (10%), xylose (5%) and mannose (4%). This polysaccharide presented an average molecular weight of 107 kDa. Scanning electron microscopy (SEM) micrographs showed that the lyophilized Navicula sp. polysaccharide is an amorphous solid with particles of irregular shapes and sharp angles. The polysaccharide at 1% (w/v) solution in water formed gels in the presence of 0.4% (w/v) FeCl3, showing elastic and viscous moduli of 1 and 0.7 Pa, respectively. SEM analysis performed on the lyophilized gel showed a compact pore structure, with a pore size of approximately 150 nm. Very few studies on the gelation of sulfated polysaccharides using trivalent ions exist in the literature, and, to the best of our knowledge, this study is the first to describe the gelation of sulfated polysaccharides extracted from Navicula sp. PMID:27483255

  8. Navicula sp. Sulfated Polysaccharide Gels Induced by Fe(III): Rheology and Microstructure.

    PubMed

    Fimbres-Olivarría, Diana; López-Elías, José Antonio; Carvajal-Millán, Elizabeth; Márquez-Escalante, Jorge Alberto; Martínez-Córdova, Luis Rafael; Miranda-Baeza, Anselmo; Enríquez-Ocaña, Fernando; Valdéz-Holguín, José Eduardo; Brown-Bojórquez, Francisco

    2016-07-30

    A sulfated polysaccharide extracted from Navicula sp. presented a yield of 4.4 (% w/w dry biomass basis). Analysis of the polysaccharide using gas chromatography showed that this polysaccharide contained glucose (29%), galactose (21%), rhamnose (10%), xylose (5%) and mannose (4%). This polysaccharide presented an average molecular weight of 107 kDa. Scanning electron microscopy (SEM) micrographs showed that the lyophilized Navicula sp. polysaccharide is an amorphous solid with particles of irregular shapes and sharp angles. The polysaccharide at 1% (w/v) solution in water formed gels in the presence of 0.4% (w/v) FeCl₃, showing elastic and viscous moduli of 1 and 0.7 Pa, respectively. SEM analysis performed on the lyophilized gel showed a compact pore structure, with a pore size of approximately 150 nm. Very few studies on the gelation of sulfated polysaccharides using trivalent ions exist in the literature, and, to the best of our knowledge, this study is the first to describe the gelation of sulfated polysaccharides extracted from Navicula sp.

  9. Ceramic femoral component fracture in total knee arthroplasty: an analysis using fractography, fourier-transform infrared microscopy, contact radiography and histology.

    PubMed

    Krueger, Alexander P; Singh, Gurpal; Beil, Frank Timo; Feuerstein, Bernd; Ruether, Wolfgang; Lohmann, Christoph H

    2014-05-01

    Ceramic components in total knee arthroplasty (TKA) are evolving. We analyze the first case of BIOLOX delta ceramic femoral component fracture. A longitudinal midline fracture in the patellar groove was present, with an intact cement mantle and no bony defects. Fractographic analysis with laser scanning microscopy and white light interferometry showed no evidence of arrest lines, hackles, wake hackles, material flaws, fatigue or crack propagation. Analysis of periprosthetic tissues with Fourier-transform infrared (FT-IR) microscopy, contact radiography, histology, and subsequent digestion and high-speed centrifugation did not show ceramic debris. A macrophage-dominated response was present around polyethylene debris. We conclude that ceramic femoral component failure in this case was related to a traumatic event. Further research is needed to determine the suitability of ceramic components in TKA. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Influence analysis for high-dimensional time series with an application to epileptic seizure onset zone detection

    PubMed Central

    Flamm, Christoph; Graef, Andreas; Pirker, Susanne; Baumgartner, Christoph; Deistler, Manfred

    2013-01-01

    Granger causality is a useful concept for studying causal relations in networks. However, numerical problems occur when applying the corresponding methodology to high-dimensional time series showing co-movement, e.g. EEG recordings or economic data. In order to deal with these shortcomings, we propose a novel method for the causal analysis of such multivariate time series based on Granger causality and factor models. We present the theoretical background, successfully assess our methodology with the help of simulated data and show a potential application in EEG analysis of epileptic seizures. PMID:23354014

  11. Relationships among sense of coherence, oral health status, nutritional status and care need level of older adults according to path analysis.

    PubMed

    Dewake, Nanae; Hamasaki, Tomoko; Sakai, Rie; Yamada, Shima; Nima, Yuko; Tomoe, Miki; Kakuta, Satoko; Iwasaki, Masanori; Soh, Inho; Shimazaki, Yoshihiro; Ansai, Toshihiro

    2017-11-01

    Sense of coherence (SOC) is a measurement of ability of an individual to cope with psychological stress and remain in good health. The aim of the present study was to examine the relationships among SOC score, oral health status, nutritional status and care need level of older adults using path analysis. We enrolled 53 older adults (17 men and 36 women) who were attending a day care service (mean age 80.4 ± 6.5 years). SOC was assessed using a 13-item, seven-scale instrument. Oral health status (number of present teeth, denture use) and nutritional status (assessed with Mini-Nutritional Assessment Short-Form) were also evaluated. Path analysis was used to examine the relationship of SOC with other related factors, including care need level. The mean SOC score was 57.0 ± 13.9. Mini-Nutritional Assessment Short-Form results showed that one participant (1.8%) was malnourished, 26 (49.1%) were at risk of malnutrition and 26 (49.1%) had normal nutritional status. Participants with high SOC scores showed a strong positive attitude, had a relatively large number of teeth, were in good nutritional condition and showed low care need levels. The present results showed that maintaining a high SOC level and good oral health help to reduce care need levels in older adults, and also prevent a worsening of their nutritional condition. Geriatr Gerontol Int 2017; 17: 2083-2088. © 2017 Japan Geriatrics Society.

  12. Fuel cell on-site integrated energy system parametric analysis of a residential complex

    NASA Technical Reports Server (NTRS)

    Simons, S. N.

    1977-01-01

    A parametric energy-use analysis was performed for a large apartment complex served by a fuel cell on-site integrated energy system (OS/IES). The variables parameterized include operating characteristics for four phosphoric acid fuel cells, eight OS/IES energy recovery systems, and four climatic locations. The annual fuel consumption for selected parametric combinations are presented and a breakeven economic analysis is presented for one parametric combination. The results show fuel cell electrical efficiency and system component choice have the greatest effect on annual fuel consumption; fuel cell thermal efficiency and geographic location have less of an effect.

  13. Experimental analysis of the flow in a two stage axial compressor at off-design conditions

    NASA Astrophysics Data System (ADS)

    Massardo, Aristide; Satta, Antonio

    1987-05-01

    The experimental analysis of the flow that develops in a two-stage axial flow compressor at off-design conditions is presented. The measurements are performed upstream, between, and downstream of the four blade rows of the compressor. The analysis shows the off-design effects on the local conditions of the flow field. Low-energy flow zones are identified, and the development of annulus-boundary-layer, secondary, and tip-clearance flows is shown. The tip-clearance flows are also present in the stator rows with various outlying conditions (stationary or rotating hub).

  14. The need for consumer behavior analysis in health care coverage decisions.

    PubMed

    Thompson, A M; Rao, C P

    1990-01-01

    Demographic analysis has been the primary form of analysis connected with health care coverage decisions. This paper reviews past demographic research and shows the need to use behavioral analyses for health care coverage policy decisions. A behavioral model based research study is presented and a case is made for integrated study into why consumers make health care coverage decisions.

  15. Flow Injection Technique for Biochemical Analysis with Chemiluminescence Detection in Acidic Media

    PubMed Central

    Chen, Jing; Fang, Yanjun

    2007-01-01

    A review with 90 references is presented to show the development of acidic chemiluminescence methods for biochemical analysis by use of flow injection technique in the last 10 years. A brief discussion of both the chemiluminescence and flow injection technique is given. The proposed methods for biochemical analysis are described and compared according to the used chemiluminescence system.

  16. Spectral analysis of the structure of ultradispersed diamonds

    NASA Astrophysics Data System (ADS)

    Uglov, V. V.; Shimanski, V. I.; Rusalsky, D. P.; Samtsov, M. P.

    2008-07-01

    The structure of ultradispersed diamonds (UDD) is studied by spectral methods. The presence of diamond crystal phase in the UDD is found based on x-ray analysis and Raman spectra. The Raman spectra also show sp2-and sp3-hybridized carbon. Analysis of IR absorption spectra suggests that the composition of functional groups present in the particles changes during the treatment.

  17. An Analysis of the Connectedness to Nature Scale Based on Item Response Theory.

    PubMed

    Pasca, Laura; Aragonés, Juan I; Coello, María T

    2017-01-01

    The Connectedness to Nature Scale (CNS) is used as a measure of the subjective cognitive connection between individuals and nature. However, to date, it has not been analyzed at the item level to confirm its quality. In the present study, we conduct such an analysis based on Item Response Theory. We employed data from previous studies using the Spanish-language version of the CNS, analyzing a sample of 1008 participants. The results show that seven items presented appropriate indices of discrimination and difficulty, in addition to a good fit. The remaining six have inadequate discrimination indices and do not present a good fit. A second study with 321 participants shows that the seven-item scale has adequate levels of reliability and validity. Therefore, it would be appropriate to use a reduced version of the scale after eliminating the items that display inappropriate behavior, since they may interfere with research results on connectedness to nature.

  18. Changes in temperature and precipitation extremes in western central Africa, Guinea Conakry, and Zimbabwe, 1955-2006

    NASA Astrophysics Data System (ADS)

    Aguilar, E.; Aziz Barry, A.; Brunet, M.; Ekang, L.; Fernandes, A.; Massoukina, M.; Mbah, J.; Mhanda, A.; Do Nascimento, D. J.; Peterson, T. C.; Thamba Umba, O.; Tomou, M.; Zhang, X.

    2009-01-01

    Understanding how extremes are changing globally, regionally, and locally is an important first step for planning appropriate adaptation measures, as changes in extremes have major impacts. The Intergovernmental Panel on Climate Change's synthesis of global extremes was not able to say anything about western central Africa, as no analysis of the region was available nor was there an adequate internationally exchanged long-term daily data set available to use for analysis of extremes. This paper presents the first analysis of extremes in this climatically important region along with analysis of Guinea Conakry and Zimbabwe. As per many other parts of the world, the analysis shows a decrease in cold extremes and an increase in warm extremes. However, while the majority of the analyzed world has shown an increase in heavy precipitation over the last half century, central Africa showed a decrease. Furthermore, the companion analysis of Guinea Conakry and Zimbabwe showed no significant increases.

  19. Analysis of thin plates with holes by using exact geometrical representation within XFEM.

    PubMed

    Perumal, Logah; Tso, C P; Leng, Lim Thong

    2016-05-01

    This paper presents analysis of thin plates with holes within the context of XFEM. New integration techniques are developed for exact geometrical representation of the holes. Numerical and exact integration techniques are presented, with some limitations for the exact integration technique. Simulation results show that the proposed techniques help to reduce the solution error, due to the exact geometrical representation of the holes and utilization of appropriate quadrature rules. Discussion on minimum order of integration order needed to achieve good accuracy and convergence for the techniques presented in this work is also included.

  20. Radionuclides in Diagnosis.

    ERIC Educational Resources Information Center

    Williams, E. D.

    1989-01-01

    Discussed is a radionuclide imaging technique, including the gamma camera, image analysis computer, radiopharmaceuticals, and positron emission tomography. Several pictures showing the use of this technique are presented. (YP)

  1. A Technical Analysis Information Fusion Approach for Stock Price Analysis and Modeling

    NASA Astrophysics Data System (ADS)

    Lahmiri, Salim

    In this paper, we address the problem of technical analysis information fusion in improving stock market index-level prediction. We present an approach for analyzing stock market price behavior based on different categories of technical analysis metrics and a multiple predictive system. Each category of technical analysis measures is used to characterize stock market price movements. The presented predictive system is based on an ensemble of neural networks (NN) coupled with particle swarm intelligence for parameter optimization where each single neural network is trained with a specific category of technical analysis measures. The experimental evaluation on three international stock market indices and three individual stocks show that the presented ensemble-based technical indicators fusion system significantly improves forecasting accuracy in comparison with single NN. Also, it outperforms the classical neural network trained with index-level lagged values and NN trained with stationary wavelet transform details and approximation coefficients. As a result, technical information fusion in NN ensemble architecture helps improving prediction accuracy.

  2. Return-to-launch-site three degree of freedom analysis, constant inertial attitude during the fuel dissipation phase

    NASA Technical Reports Server (NTRS)

    Bown, R. L.; Winans, L. C.

    1975-01-01

    Results are presented of a study to show the effect of selecting a constant inertial attitude during the fuel dissipation phase of a return-to-launch-site abort. Results are also presented which show that the selection of the constant inertial attitude will affect the arrival point on the range-velocity target line. An alternate selection of the inertial attitude will provide control over the trajectory shape.

  3. Some selected quantitative methods of thermal image analysis in Matlab.

    PubMed

    Koprowski, Robert

    2016-05-01

    The paper presents a new algorithm based on some selected automatic quantitative methods for analysing thermal images. It shows the practical implementation of these image analysis methods in Matlab. It enables to perform fully automated and reproducible measurements of selected parameters in thermal images. The paper also shows two examples of the use of the proposed image analysis methods for the area of ​​the skin of a human foot and face. The full source code of the developed application is also provided as an attachment. The main window of the program during dynamic analysis of the foot thermal image. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Provoking Reflective Thinking in Post Observation Conversations

    ERIC Educational Resources Information Center

    Kim, Younhee; Silver, Rita Elaine

    2016-01-01

    We present a micro-analysis of post observation conversations between classroom teachers and mentors. Using the approach of conversation analysis, we show how the sequential organization of an episode (i.e., who initiates the interaction, question format used by mentors) could potentially serve to provoke or hinder teacher reflection. Our analysis…

  5. Flocking of the Motsch-Tadmor Model with a Cut-Off Interaction Function

    NASA Astrophysics Data System (ADS)

    Jin, Chunyin

    2018-04-01

    In this paper, we study the flocking behavior of the Motsch-Tadmor model with a cut-off interaction function. Our analysis shows that connectedness is important for flocking of this kind of model. Fortunately, we get a sufficient condition imposed only on the model parameters and initial data to guarantee the connectedness of the neighbor graph associated with the system. Then we present a theoretical analysis for flocking, and show that the system achieves consensus at an exponential rate.

  6. Theoretical analysis of incompressible flow through a radial-inlet centrifugal impeller at various weight flows

    NASA Technical Reports Server (NTRS)

    Kramer, James J; Prian, Vasily D; Wu, Chung-Hua

    1956-01-01

    A method for the solution of the incompressible nonviscous flow through a centrifugal impeller, including the inlet region, is presented. Several numerical solutions are obtained for four weight flows through an impeller at one operating speed. These solutions are refined in the leading-edge region. The results are presented in a series of figures showing streamlines and relative velocity contours. A comparison is made with the results obtained by using a rapid approximate method of analysis.

  7. Dynamic competitive probabilistic principal components analysis.

    PubMed

    López-Rubio, Ezequiel; Ortiz-DE-Lazcano-Lobato, Juan Miguel

    2009-04-01

    We present a new neural model which extends the classical competitive learning (CL) by performing a Probabilistic Principal Components Analysis (PPCA) at each neuron. The model also has the ability to learn the number of basis vectors required to represent the principal directions of each cluster, so it overcomes a drawback of most local PCA models, where the dimensionality of a cluster must be fixed a priori. Experimental results are presented to show the performance of the network with multispectral image data.

  8. Multi-machine analysis of termination scenarios with comparison to simulations of controlled shutdown of ITER discharges

    DOE PAGES

    de Vries, Peter C.; Luce, Timothy C.; Bae, Young-soon; ...

    2017-11-22

    To improve our understanding of the dynamics and control of ITER terminations, a study has been carried out on data from existing tokamaks. The aim of this joint analysis is to compare the assumptions for ITER terminations with the present experience basis. The study examined the parameter ranges in which present day devices operated during their terminations, as well as the dynamics of these parameters. The analysis of a database, built using a selected set of experimental termination cases, showed that, the H-mode density decays slower than the plasma current ramp-down. The consequential increase in fGW limits the duration ofmore » the H-mode phase or result in disruptions. The lower temperatures after the drop out of H-mode will allow the plasma internal inductance to increase. But vertical stability control remains manageable in ITER at high internal inductance when accompanied by a strong elongation reduction. This will result in ITER terminations remaining longer at low q (q95~3) than most present-day devices during the current ramp-down. A fast power ramp-down leads to a larger change in βp at the H-L transition, but the experimental data showed that these are manageable for the ITER radial position control. The analysis of JET data shows that radiation and impurity levels significantly alter the H-L transition dynamics. Self-consistent calculations of the impurity content and resulting radiation should be taken into account when modelling ITER termination scenarios. Here, the results from this analysis can be used to better prescribe the inputs for the detailed modelling and preparation of ITER termination scenarios.« less

  9. Multi-machine analysis of termination scenarios with comparison to simulations of controlled shutdown of ITER discharges

    NASA Astrophysics Data System (ADS)

    de Vries, P. C.; Luce, T. C.; Bae, Y. S.; Gerhardt, S.; Gong, X.; Gribov, Y.; Humphreys, D.; Kavin, A.; Khayrutdinov, R. R.; Kessel, C.; Kim, S. H.; Loarte, A.; Lukash, V. E.; de la Luna, E.; Nunes, I.; Poli, F.; Qian, J.; Reinke, M.; Sauter, O.; Sips, A. C. C.; Snipes, J. A.; Stober, J.; Treutterer, W.; Teplukhina, A. A.; Voitsekhovitch, I.; Woo, M. H.; Wolfe, S.; Zabeo, L.; the Alcator C-MOD Team; the ASDEX Upgrade Team; the DIII-D Team; the EAST Team; contributors, JET; the KSTAR Team; the NSTX-U Team; the TCV Team; IOS members, ITPA; experts

    2018-02-01

    To improve our understanding of the dynamics and control of ITER terminations, a study has been carried out on data from existing tokamaks. The aim of this joint analysis is to compare the assumptions for ITER terminations with the present experience basis. The study examined the parameter ranges in which present day devices operated during their terminations, as well as the dynamics of these parameters. The analysis of a database, built using a selected set of experimental termination cases, showed that, the H-mode density decays slower than the plasma current ramp-down. The consequential increase in f GW limits the duration of the H-mode phase or result in disruptions. The lower temperatures after the drop out of H-mode will allow the plasma internal inductance to increase. But vertical stability control remains manageable in ITER at high internal inductance when accompanied by a strong elongation reduction. This will result in ITER terminations remaining longer at low q (q 95 ~ 3) than most present-day devices during the current ramp-down. A fast power ramp-down leads to a larger change in β p at the H-L transition, but the experimental data showed that these are manageable for the ITER radial position control. The analysis of JET data shows that radiation and impurity levels significantly alter the H-L transition dynamics. Self-consistent calculations of the impurity content and resulting radiation should be taken into account when modelling ITER termination scenarios. The results from this analysis can be used to better prescribe the inputs for the detailed modelling and preparation of ITER termination scenarios.

  10. A Mean variance analysis of arbitrage portfolios

    NASA Astrophysics Data System (ADS)

    Fang, Shuhong

    2007-03-01

    Based on the careful analysis of the definition of arbitrage portfolio and its return, the author presents a mean-variance analysis of the return of arbitrage portfolios, which implies that Korkie and Turtle's results ( B. Korkie, H.J. Turtle, A mean-variance analysis of self-financing portfolios, Manage. Sci. 48 (2002) 427-443) are misleading. A practical example is given to show the difference between the arbitrage portfolio frontier and the usual portfolio frontier.

  11. Motivations and self-presentation strategies on Korean-based "Cyworld" weblog format personal homepages.

    PubMed

    Jung, Taejin; Youn, Hyunsook; McClung, Steven

    2007-02-01

    The main purposes of this study are to find out individuals' motives and interpersonal self-presentation strategies on constructing Korean weblog format personal homepage (e.g., "Cyworld mini-homepage"). The study also attempts to find predictor motives that lead to the activities of posting and maintaining a homepage and compare the self-presentation strategies used on the Web with those commonly used in interpersonal situations. By using a principal component factor analysis, four salient self-presentation strategy factors and five interpretable mini-homepage hosting motive factors were identified. Accompanying multiple regression analysis shows that entertainment and personal income factors are major predictors in explaining homepage maintenance expenditures and frequencies of updating.

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Saito, Kayoko; Ikeya, Kiyoko; Kondo, Eri

    Mosaicism is a mixed state, with two cell populations of different genetic origins caused by a cell mutation occurring after fertilization. In the present case, DNA analysis of lymphocytes led to a DMD diagnosis before death. Postmortem immunocytochemical and DNA analysis showed somatic mosaicism. At age 18 years, blood lymphocyte DNA analysis showed a DMD gene deletion, upstream from exon 7 to the 5{prime} end containing both muscle and brain promoters. As the patient`s mother and elder sister had no deletions, he was considered to have a new mutation. Immunocytochemical studies of postmortem tissues showed that dystrophin was absent frommore » the tongue, deltoid, intercostal, psoas and rectus femoris muscles, but there was a mix of dystrophin-positive and negative fibers in the rectus abdominis, cardiac, temporalis and sternocleidomastoid muscles. All diaphragm cells were dystrophin positive. Polymerase chain reaction (PCR) amplification from all tissues except the temporalis and sternocleidomastoid muscles, diaphragm and kidney, in which no deletion was found, showed the deletion from at least exon 6 to the 5{prime} end containing both muscle and brain promoters. In this case, a genomic deletion of the DMD gene contributed to the formation of tissues derived from both ectoderm and endoderm, and cells of mesodermal origin showed genotypic and phenotypic heterogeneity. Our results indicate a mutation of the present case may have occurred just before the period of germ layer formation. 34 refs., 7 figs.« less

  13. Cryptorchidism due to chromosome 5q inversion duplication.

    PubMed

    Dutta, M K; Gundgurthi, A; Garg, M K; Pakhetr, R

    2013-12-01

    We present a 15 year old boy who was born out of a non consanguineous marriage, and presented with bilateral cryptorchidism, mental retardation, facial dysmorphism, hypergonadotrophic hypogonadism with failure of anatomical and biochemical localisation of testes. Karyotype analysis showed 46 XY with inverted duplication on chromosome 5q22-31.

  14. Characterization of functional brain activity and connectivity using EEG and fMRI in patients with sickle cell disease.

    PubMed

    Case, Michelle; Zhang, Huishi; Mundahl, John; Datta, Yvonne; Nelson, Stephen; Gupta, Kalpna; He, Bin

    2017-01-01

    Sickle cell disease (SCD) is a red blood cell disorder that causes many complications including life-long pain. Treatment of pain remains challenging due to a poor understanding of the mechanisms and limitations to characterize and quantify pain. In the present study, we examined simultaneously recording functional MRI (fMRI) and electroencephalogram (EEG) to better understand neural connectivity as a consequence of chronic pain in SCD patients. We performed independent component analysis and seed-based connectivity on fMRI data. Spontaneous power and microstate analysis was performed on EEG-fMRI data. ICA analysis showed that patients lacked activity in the default mode network (DMN) and executive control network compared to controls. EEG-fMRI data revealed that the insula cortex's role in salience increases with age in patients. EEG microstate analysis showed patients had increased activity in pain processing regions. The cerebellum in patients showed a stronger connection to the periaqueductal gray matter (involved in pain inhibition), and negative connections to pain processing areas. These results suggest that patients have reduced activity of DMN and increased activity in pain processing regions during rest. The present findings suggest resting state connectivity differences between patients and controls can be used as novel biomarkers of SCD pain.

  15. Data for a proteomic analysis of p53-independent induction of apoptosis by bortezomib

    PubMed Central

    Yerlikaya, Azmi; Okur, Emrah; Tarık Baykal, Ahmet; Acılan, Ceyda; Boyacı, İhsan; Ulukaya, Engin

    2014-01-01

    This data article contains data related to the research article entitled, “A proteomic analysis of p53-independent induction of apoptosis by bortezomib in 4T1 breast cancer cell line” by Yerlikaya et al. [1]. The research article presented 2-DE and nLC-MS/MS based proteomic analysis of proteasome inhibitor bortezomib-induced changes in the expression of cellular proteins. The report showed that GRP78 and TCEB2 were over-expressed in response to treatment with bortezomib for 24 h. In addition, the report demonstrated that Hsp70, the 26S proteasome non-ATPase regulatory subunit 14 and sequestosome 1 were increased at least 2 fold in p53-deficient 4T1 cells. The data here show for the first time the increased expressions of Card10, Dffb, Traf3 and Trp53bp2 in response to inhibition of the 26S proteasome. The information presented here also shows that both Traf1 and Xiap (a member of IAPs) are also downregulated simultaneously upon proteasomal inhibition. The increases in the level of Card10 and Trp53bp2 proteins were verified by Western blot analysis in response to varying concentrations of bortezomib for 24 h. PMID:26217687

  16. Receive-Noise Analysis of Capacitive Micromachined Ultrasonic Transducers.

    PubMed

    Bozkurt, Ayhan; Yaralioglu, G Goksenin

    2016-11-01

    This paper presents an analysis of thermal (Johnson) noise received from the radiation medium by otherwise noiseless capacitive micromachined ultrasonic transducer (CMUT) membranes operating in their fundamental resonance mode. Determination of thermal noise received by multiple numbers of transducers or a transducer array requires the assessment of cross-coupling through the radiation medium, as well as the self-radiation impedance of the individual transducer. We show that the total thermal noise received by the cells of a CMUT has insignificant correlation, and is independent of the radiation impedance, but is only determined by the mass of each membrane and the electromechanical transformer ratio. The proof is based on the analytical derivations for a simple transducer with two cells, and extended to transducers with numerous cells using circuit simulators. We used a first-order model, which incorporates the fundamental resonance of the CMUT. Noise power is calculated by integrating over the entire spectrum; hence, the presented figures are an upper bound for the noise. The presented analyses are valid for a transimpedance amplifier in the receive path. We use the analysis results to calculate the minimum detectable pressure of a CMUT. We also provide an analysis based on the experimental data to show that output noise power is limited by and comparable to the theoretical upper limit.

  17. Application of Microchip for Biomarker Analysis

    NASA Astrophysics Data System (ADS)

    Kataoka, Masatoshi; Yatsushiro, Shouki; Yamamura, Shouhei; Abe, Hiroko

    Microchip technologies have received considerable attention, due to their competitive advantages, especially in regards to reduced sample and reagent consumption, analysis time, and easy operation. This approach has been successfully used to analyze DNA, amino acids, proteins, and carbohydrates. In the present study, we showed the potential of microchip technologies for the biomarker analysis, blood carbohydrate analysis on microchip electrophoresis, quantitative analysis of protein with antigen-antibody reaction on microchip, and the detection of malaria-infected erythrocyte with a cell microarray chip.

  18. Spatiotemporal pH dynamics in concentration polarization near ion-selective membranes.

    PubMed

    Andersen, Mathias B; Rogers, David M; Mai, Junyu; Schudel, Benjamin; Hatch, Anson V; Rempe, Susan B; Mani, Ali

    2014-07-08

    We present a detailed analysis of the transient pH dynamics for a weak, buffered electrolyte subject to voltage-driven transport through an ion-selective membrane. We show that pH fronts emanate from the concentration polarization zone next to the membrane and that these propagating fronts change the pH in the system several units from its equilibrium value. The analysis is based on a 1D model using the unsteady Poisson-Nernst-Planck equations with nonequilibrium chemistry and without assumptions of electroneutrality or asymptotically thin electric double layers. Nonequilibrium chemical effects, especially for water splitting, are shown to be important for the dynamical and spatiotemporal evolution of the pH fronts. Nonetheless, the model also shows that at steady state the assumption of chemical equilibrium can still lead to good approximations of the global pH distribution. Moreover, our model shows that the transport of the hydronium ion in the extended space charge region is governed by a balance between electromigration and water self-ionization. On the basis of this observation, we present a simple model showing that the net flux of the hydronium ion is proportional to the length of the extended space charge region and the water self-ionization rate. To demonstrate these effects in practice, we have adopted the experiment of Mai et al. (Mai, J.; Miller, H.; Hatch, A. V. Spatiotemporal Mapping of Concentration Polarization Induced pH Changes at Nanoconstrictions. ACS Nano 2012, 6, 10206) as a model problem, and by including the full chemistry and transport, we show that the present model can capture the experimentally observed pH fronts. Our model can, among other things, be used to predict and engineer pH dynamics, which can be essential to the performance of membrane-based systems for biochemical separation and analysis.

  19. EMBLA 2002: an Optical and Ground Survey in Hessdalen

    NASA Astrophysics Data System (ADS)

    Teodorani, M.; Nobili, G.

    2002-10-01

    A two-weeks scientific expedition to Hessdalen, aimed at investigating on field mysterious atmospheric light-phenomena, was carried out in August 2002 by the physics section of an italian team of scientists. Results are presented and discussed. Photometric analysis shows that the light-phenomenon is able to produce a luminous power of up-to 100 kW. A 3-D analysis of photo frames shows that the luminous phenomenon doesn't resemble canonical plasma features (a sharply gaussian PSF) unless the light phenomenon is caused by one recently discovered natural light-ball of BL type whose light-distribution (PSF) might be able to simulate an uniformly illuminated solid. A comparison of the light-distribution in different time-sequential frames shows that apparent slightly exponential wings of the PSF features are probably due to variations of atmospheric turbulence and transparency and not to intrinsic properties. Maximum phases of luminosity of the radiating surface are demonstrated to be due to the sudden apparition of a cluster of co-existing light-balls at constant temperature, while the inflation of light-balls is ruled out. Spectra show no resolved lines but a three-peaked feature which might be attributed both to some kind of artificial illumination system and to a mixture of many blended lines due to several chemical elements (more possibly: silicon). The results of a lab analysis of ground samples shows that some powder which was collected near a river contains an anomalous iron sphere of micrometric dimensions. A biophysical research-proposal aimed at studying the relation between the EM field produced by the phenomenon and the electrical activity of the human body is also presented. On the basis of this third explorative experience, the importance of having at disposal a sophisticated opto-electronic portable station (missing at present) is stressed for the future.

  20. Some neutron and gamma radiation characteristics of plutonium cermet fuel for isotopic power sources

    NASA Technical Reports Server (NTRS)

    Neff, R. A.; Anderson, M. E.; Campbell, A. R.; Haas, F. X.

    1972-01-01

    Gamma and neutron measurements on various types of plutonium sources are presented in order to show the effects of O-17, O-18 F-19, Pu-236, age of the fuel, and size of the source on the gamma and neutron spectra. Analysis of the radiation measurements shows that fluorine is the main contributor to the neutron yields from present plutonium-molybdenum cermet fuel, while both fluorine and Pu-236 daughters contribute significantly to the gamma ray intensities.

  1. Understanding Mott-Schottky Measurements under Illumination in Organic Bulk Heterojunction Solar Cells

    NASA Astrophysics Data System (ADS)

    Zonno, Irene; Martinez-Otero, Alberto; Hebig, Jan-Christoph; Kirchartz, Thomas

    2017-03-01

    The Mott-Schottky analysis in the dark is a frequently used method to determine the doping concentration of semiconductors from capacitance-voltage measurements, even for such complex systems as polymer:fullerene blends used for organic solar cells. While the analysis of capacitance-voltage measurements in the dark is relatively well established, the analysis of data taken under illumination is currently not fully understood. Here, we present experiments and simulations to show which physical mechanisms affect the Mott-Schottky analysis under illumination. We show that the mobility of the blend has a major influence on the shape of the capacitance-voltage curve and can be obtained from data taken under reverse bias. In addition, we show that the apparent shift of the built-in voltage observed previously can be explained by a shift of the onset of space-charge-limited collection with illumination intensity.

  2. Geometrically nonlinear analysis of adhesively bonded joints

    NASA Technical Reports Server (NTRS)

    Dattaguru, B.; Everett, R. A., Jr.; Whitcomb, J. D.; Johnson, W. S.

    1982-01-01

    A geometrically nonlinear finite element analysis of cohesive failure in typical joints is presented. Cracked-lap-shear joints were chosen for analysis. Results obtained from linear and nonlinear analysis show that nonlinear effects, due to large rotations, significantly affect the calculated mode 1, crack opening, and mode 2, inplane shear, strain-energy-release rates. The ratio of the mode 1 to mode 2 strain-energy-relase rates (G1/G2) was found to be strongly affected by he adhesive modulus and the adherend thickness. The ratios between 0.2 and 0.8 can be obtained by varying adherend thickness and using either a single or double cracked-lap-shear specimen configuration. Debond growth rate data, together with the analysis, indicate that mode 1 strain-energy-release rate governs debond growth. Results from the present analysis agree well with experimentally measured joint opening displacements.

  3. Steroid-antivirals treatment versus steroids alone for the treatment of Bell's palsy: a meta-analysis.

    PubMed

    Dong, Yabing; Zhu, Yong; Ma, Chuan; Zhao, Huaqiang

    2015-01-01

    To illustrate whether the steroid-antivirals treatment could acquire a better recovery in patients with Bell's palsy than the steroids alone treatment. We conducted an exhaustive search over Pub med/Medline, Ovid, Elsevier search engines and the Cochrane library thereby collecting the randomized controlled trials in the treatment of patients with Bell's palsy with steroid-antivirals and steroids. The qualities of relevant articles were assessed by GRADE, which was used to present the overall quality of evidence as recommended by the Cochrane Handbook for Systematic Reviews of Interventions. Two investigators evaluated these papers independently, and resolved the disagreements by discussion. At last 8 eligible papers (1816 patients included: 896 treated with steroid-antivirals and 920 treated with steroids alone) match the criteria. Owing to the result (chi(2) = 12.57, P = 0.08, I(2) = 44%) presented by the formal test for heterogeneity, the fixed effect meta-analysis model was chosen. The facial muscle recovery between the steroids-antivirals group and the steroids alone group show significant differences (OR = 1.52, 95% CI: 1.20-1.94), while the statistical outcome of adverse effect shows no statistical significance (OR = 1.28, 95% CI: 0.71-2.31). The present meta-analysis indicates that the steroid-antivirals treatment could improve the recovery rate in patients with Bell's palsy when comparing with the steroid alone treatment. This meta-analysis showed that the steroid-antivirals treatment achieved the better outcomes in patients with Bell's palsy. Clinicians should consider that steroid-antivirals therapy is an alternative choice for the patients with Bell's palsy.

  4. Androgen receptor modulation following combination exposure to brominated flame-retardants.

    PubMed

    Kharlyngdoh, Joubert Banjop; Pradhan, Ajay; Olsson, Per-Erik

    2018-03-19

    Endocrine disrupting compounds can interfere with androgen receptor (AR) signaling and disrupt steroidogenesis leading to reproductive failure. The brominated flame-retardant (BFR) 1, 2-dibromo-4-(1, 2-dibromoethyl) cyclohexane (TBECH), is an agonist to human, chicken and zebrafish AR. Recently another group of alternative BFRs, allyl 2, 4, 6-tribromophenyl ether (ATE), and 2, 3-dibromopropyl 2, 4, 6-tribromophenyl ether (DPTE) along with its metabolite 2-bromoallyl 2, 4, 6-tribromophenyl ether (BATE) were identified as potent human AR antagonists. These alternative BFRs are present in the environment. The aim of the present study was to determine the effect of mixed exposures to the AR agonist and the AR antagonists at environmentally relevant concentrations. In vitro reporter luciferase assay showed that the AR antagonists, when present at concentration higher than TBECH, were able to inhibit TBECH-mediated AR activity. These AR antagonists also promoted AR nuclear translocation. In vitro gene expression analysis in the non-tumorigenic human prostate epithelial cell RWPE1 showed that TBECH induced AR target genes whereas DPTE repressed these genes. Further analysis of steroidogenic genes showed that TBECH up-regulated most of the genes while DPTE down-regulated the same genes. The results indicate that when TBECH and DPTE are present together they will antagonize each other, thereby reducing their individual effects.

  5. Molecular analysis of partial VP-2 gene amplified from rectal swab samples of diarrheic dogs in Pakistan confirms the circulation of canine parvovirus genetic variant CPV-2a and detects sequences of feline panleukopenia virus (FPV).

    PubMed

    Ahmed, Nisar; Riaz, Adeel; Zubair, Zahra; Saqib, Muhammad; Ijaz, Sehrish; Nawaz-Ul-Rehman, Muhammad Shah; Al-Qahtani, Ahmed; Mubin, Muhammad

    2018-03-15

    The infection in dogs due to canine parvovirus (CPV), is a highly contagious one with high mortality rate. The present study was undertaken for a detailed genetic analysis of partial VP2 gene i.e., 630 bp isolated from rectal swab samples of infected domestic and stray dogs from all areas of district Faisalabad. Monitoring of viruses is important, as continuous prevalence of viral infection might be associated with emergence of new virulent strains. In the present study, 40 rectal swab samples were collected from diarrheic dogs from different areas of district Faisalabad, Pakistan, in 2014-15 and screened for the presence of CPV by immunochromatography. Most of these dogs were stray dogs showing symptoms of diarrhea. Viral DNA was isolated and partial VP2 gene was amplified using gene specific primer pair Hfor/Hrev through PCR. Amplified fragments were cloned in pTZ57R/T (Fermentas) and completely sequenced. Sequences were analyzed and assembled by the Lasergene DNA analysis package (v8; DNAStar Inc., Madison, WI, USA). The results with immunochromatography showed that 33/40 (82%) of dogs were positive for CPV. We were able to amplify a fragment of 630 bp from 25 samples. In 25 samples the sequences of CPV-2a were detected showing the amino acid substitution Ser297Ala and presence of amino acid (426-Asn) in partial VP2 protein. Interestingly the BLAST analysis showed the of feline panleukopenia virus (FPV) sequences in 3 samples which were already positive for new CPV-2a, with 99% sequence homology to other FPV sequences present in GenBank. Phylogenetic analysis showed clustering of partial CPV-VP-2 gene with viruses from China, India, Japan and Uruguay identifying a new variant, whereas the 3 FPV sequences showed immediate ancestral relationship with viruses from Portugal, South Africa and USA. Interesting observation was that CPV are clustering away from the commercial vaccine strains. In this work we provide a better understanding of CPV prevailing in Pakistan at molecular level. The detection of FPV could be a case of real co-infection or a case of dual presence, due to ingestion of contaminated food.

  6. Facilitating an L2 Book Club: A Conversation-Analytic Study of Task Management

    ERIC Educational Resources Information Center

    Ro, Eunseok

    2018-01-01

    This study employs conversation analysis to examine a facilitator's interactional practices in the post-expansion phase of students' presentations in the context of a book club for second language learning. The analysis shows how the facilitator establishes intersubjectivity with regard to the ongoing task and manages students' task performance.…

  7. A Hands-On Experience of English Language Teachers as Researchers

    ERIC Educational Resources Information Center

    Yayli, Demet

    2012-01-01

    This study presents the results of a teacher research project. The analysis aimed to explore both the four teacher researchers' interpretations of conducting research in English language teaching and the nature of their collaboration with their supervisor in the procedure. The results showed that qualitative data analysis and interpreting the…

  8. Soy Consumption of Prostate Cancer Risk in Men: A Meta-Analysis

    USDA-ARS?s Scientific Manuscript database

    Soy is a major plant source of dietary protein to humans. Epidemiologic studies show that consumption of soy foods may be related to a reduction in cancer risk in humans. The purpose of the present study was to conduct a meta-analysis on the association between soy consumption and prostate cancer r...

  9. Indiana's timber resource, 1986: an analysis.

    Treesearch

    John S. Jr. Spencer; Neal P. Kingsley; Robert W. Mayer

    1990-01-01

    The third inventory of Indiana's timber resource shows that area of timberland increased from 3.9 to 4.3 million acres between 1967 and 1986, and growing-stock volume gained from 3.7 to 5.2 billion cubic feet. Presented are analysis and statistics on forest area and timber volume, growth, mortality, removals, and projections.

  10. Penetrating a Wall of Introspection: A Critical Attrition Analysis

    ERIC Educational Resources Information Center

    Johannsen, Bjorn Friis; Rump, Camilla Osterberg; Linder, Cedric

    2013-01-01

    This paper presents a critical analysis of student discourse on attrition as it unfolds in interviews on early departure from higher education. A synthesis of relevant studies and modelling done in the field shows that essential aspects affecting attrition and retention can be effectively conceptualized and acted upon in terms of the interplay…

  11. Doctoral Supervision in a Cross-Cultural Context: Issues Affecting Supervisors and Candidates

    ERIC Educational Resources Information Center

    Winchester-Seeto, Theresa; Homewood, Judi; Thogersen, Jane; Jacenyik-Trawoger, Christa; Manathunga, Catherine; Reid, Anna; Holbrook, Allyson

    2014-01-01

    This article presents an analysis of rich data, gathered from interviews with 46 candidates and 38 supervisors from three Australian universities, about experiences of doctoral supervision in cross-cultural situations. Our analysis shows that many of the issues reported by international candidates are the same as those encountered by domestic…

  12. Associations of Parenting Dimensions and Styles with Externalizing Problems of Children and Adolescents: An Updated Meta-Analysis

    ERIC Educational Resources Information Center

    Pinquart, Martin

    2017-01-01

    The present meta-analysis integrates research from 1,435 studies on associations of parenting dimensions and styles with externalizing symptoms in children and adolescents. Parental warmth, behavioral control, autonomy granting, and an authoritative parenting style showed very small to small negative concurrent and longitudinal associations with…

  13. Three-dimensional thermal analysis of a high-level waste repository

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Altenbach, T.J.

    1979-04-01

    The analysis used the TRUMP computer code to evaluate the thermal fields for six repository scenarios that studied the effects of room ventilation, room backfill, and repository thermal diffusivity. The results for selected nodes are presented as plots showing the effect of temperature as a function of time. 15 figures, 6 tables.

  14. Performance Management in the French System of Secondary-Teacher Training

    ERIC Educational Resources Information Center

    Tchibozo, Guy

    2005-01-01

    The present study focuses on performance analysis and performance management in teacher training in France. After a brief summary of the French system of secondary-teacher training, determinants affecting performance are analyzed. The analysis shows that three determinants--the number of external competitors, the size of a department and the…

  15. Vocational Preparation for Women: A Critical Analysis.

    ERIC Educational Resources Information Center

    Steiger, JoAnn

    In this analysis of vocational preparation for women material is presented to substantiate the claim that women are joining the labor force in increasing numbers and their career opportunities are expanding, but that the educational system has failed to respond. Statistical data is cited showing that women have traditionally been employed in just…

  16. Environmental Pollution Control Policy-Making: An Analysis of Elite Perceptions and Preferences

    ERIC Educational Resources Information Center

    Althoff, Phillip; Greig, William H.

    1974-01-01

    This article is based on an analysis of the perceptions and preferences of elite groups concerning environmental pollution control policy making. Results showed that although the groups agreed that present methods were inadequate, they were, nevertheless, unable to agree upon the nature of a future policy-making system. (MA)

  17. Narrow band quantitative and multivariate electroencephalogram analysis of peri-adolescent period.

    PubMed

    Martinez, E I Rodríguez; Barriga-Paulino, C I; Zapata, M I; Chinchilla, C; López-Jiménez, A M; Gómez, C M

    2012-08-24

    The peri-adolescent period is a crucial developmental moment of transition from childhood to emergent adulthood. The present report analyses the differences in Power Spectrum (PS) of the Electroencephalogram (EEG) between late childhood (24 children between 8 and 13 years old) and young adulthood (24 young adults between 18 and 23 years old). The narrow band analysis of the Electroencephalogram was computed in the frequency range of 0-20 Hz. The analysis of mean and variance suggested that six frequency ranges presented a different rate of maturation at these ages, namely: low delta, delta-theta, low alpha, high alpha, low beta and high beta. For most of these bands the maturation seems to occur later in anterior sites than posterior sites. Correlational analysis showed a lower pattern of correlation between different frequencies in children than in young adults, suggesting a certain asynchrony in the maturation of different rhythms. The topographical analysis revealed similar topographies of the different rhythms in children and young adults. Principal Component Analysis (PCA) demonstrated the same internal structure for the Electroencephalogram of both age groups. Principal Component Analysis allowed to separate four subcomponents in the alpha range. All these subcomponents peaked at a lower frequency in children than in young adults. The present approaches complement and solve some of the incertitudes when the classical brain broad rhythm analysis is applied. Children have a higher absolute power than young adults for frequency ranges between 0-20 Hz, the correlation of Power Spectrum (PS) with age and the variance age comparison showed that there are six ranges of frequencies that can distinguish the level of EEG maturation in children and adults. The establishment of maturational order of different frequencies and its possible maturational interdependence would require a complete series including all the different ages.

  18. Post-Flight Analysis of the Guidance, Navigation, and Control Performance During Orion Exploration Flight Test 1

    NASA Technical Reports Server (NTRS)

    Barth, Andrew; Mamich, Harvey; Hoelscher, Brian

    2015-01-01

    The first test flight of the Orion Multi-Purpose Crew Vehicle presented additional challenges for guidance, navigation and control as compared to a typical re-entry from the International Space Station or other Low Earth Orbit. An elevated re-entry velocity and steeper flight path angle were chosen to achieve aero-thermal flight test objectives. New IMU's, a GPS receiver, and baro altimeters were flight qualified to provide the redundant navigation needed for human space flight. The guidance and control systems must manage the vehicle lift vector in order to deliver the vehicle to a precision, coastal, water landing, while operating within aerodynamic load, reaction control system, and propellant constraints. Extensive pre-flight six degree-of-freedom analysis was performed that showed mission success for the nominal mission as well as in the presence of sensor and effector failures. Post-flight reconstruction analysis of the test flight is presented in this paper to show whether that all performance metrics were met and establish how well the pre-flight analysis predicted the in-flight performance.

  19. Analysis of seismic patterns observed at Nevado del Ruiz volcano, Colombia during August September 1985

    NASA Astrophysics Data System (ADS)

    Martinelli, Bruno

    1990-07-01

    The seismic activity of the Nevado del Ruiz volcano was monitored during August-September 1985 using a three-component portable seismograph station placed on the upper part of the volcano. The objective was to investigate the frequency content of the seismic signals and the possible sources of the volcanic tremor. The seismicity showed a wide spectrum of signals, especially at the beginning of September. Some relevant patterns from the collected records, which have been analyzed by spectrum analysis, are presented. For the purpose of analysis, the records have been divided into several categories such as long-period events, tremor, cyclic tremor episodes, and strong seismic activity on September 8, 1985. The origin of the seismic signals must be considered in relation to the dynamical and acoustical properties of fluids and the shape and dimensions of the volcano's conduits. The main results of the present experiment and analysis show that the sources of the seismic signals are within the volcanic edifice. The signal characteristics indicate that the sources lie in fluid-phase interactions rather than in brittle fracturing of solid components.

  20. Exploiting automatically generated databases of traffic signs and road markings for contextual co-occurrence analysis

    NASA Astrophysics Data System (ADS)

    Hazelhoff, Lykele; Creusen, Ivo M.; Woudsma, Thomas; de With, Peter H. N.

    2015-11-01

    Combined databases of road markings and traffic signs provide a complete and full description of the present traffic legislation and instructions. Such databases contribute to efficient signage maintenance, improve navigation, and benefit autonomous driving vehicles. A system is presented for the automated creation of such combined databases, which additionally investigates the benefit of this combination for automated contextual placement analysis. This analysis involves verification of the co-occurrence of traffic signs and road markings to retrieve a list of potentially incorrectly signaled (and thus potentially unsafe) road situations. This co-occurrence verification is specifically explored for both pedestrian crossings and yield situations. Evaluations on 420 km of road have shown that individual detection of traffic signs and road markings denoting these road situations can be performed with accuracies of 98% and 85%, respectively. Combining both approaches shows that over 95% of the pedestrian crossings and give-way situations can be identified. An exploration toward additional co-occurrence analysis of signs and markings shows that inconsistently signaled situations can successfully be extracted, such that specific safety actions can be directed toward cases lacking signs or markings, while most consistently signaled situations can be omitted from this analysis.

  1. Application of the boundary element method to the micromechanical analysis of composite materials

    NASA Technical Reports Server (NTRS)

    Goldberg, R. K.; Hopkins, D. A.

    1995-01-01

    A new boundary element formulation for the micromechanical analysis of composite materials is presented in this study. A unique feature of the formulation is the use of circular shape functions to convert the two-dimensional integrations of the composite fibers to one-dimensional integrations. To demonstrate the applicability of the formulations, several example problems including elastic and thermal analysis of laminated composites and elastic analyses of woven composites are presented and the boundary element results compared to experimental observations and/or results obtained through alternate analytical procedures. While several issues remain to be addressed in order to make the methodology more robust, the formulations presented here show the potential in providing an alternative to traditional finite element methods, particularly for complex composite architectures.

  2. Evolutionary technology adoption in an oligopoly market with forward-looking firms

    NASA Astrophysics Data System (ADS)

    Lamantia, F.; Radi, D.

    2018-05-01

    In this paper, we propose an evolutionary oligopoly game of technology adoption in a market with isoelastic demand and two possible (linear) production technologies. While one technology is characterized by lower marginal costs, the magnitude of fixed costs entails that a technology does not necessarily dominate the other. Firms are forward-looking as they assess the profitability of employing either technology according to the corresponding expected profits. The dynamics of the system is studied through a piecewise-smooth map, for which we present a local stability analysis of equilibria and show the occurrence of smooth and border collision bifurcations. Global analysis of the model is also presented to show the coexistence of attractors and its economic significance. This investigation reveals that firms can fail to learn to adopt the more efficient technology.

  3. Navier-Stokes analysis of a liquid rocket engine disk cavity

    NASA Technical Reports Server (NTRS)

    Benjamin, Theodore G.; Mcconnaughey, Paul K.

    1991-01-01

    This paper presents a Navier-Stokes analysis of hydrodynamic phenomena occurring in the aft disk cavity of a liquid rocket engine turbine. The cavity analyzed in the Space Shuttle Main Engine Alternate Turbopump currently being developed by NASA and Pratt and Whitney. Comparison of results obtained from the Navier-Stokes code for two rotating disk datasets available in the literature are presented as benchmark validations. The benchmark results obtained using the code show good agreement relative to experimental data, and the turbine disk cavity was analyzed with comparable grid resolution, dissipation levels, and turbulence models. Predicted temperatures in the cavity show that little mixing of hot and cold fluid occurs in the cavity and the flow is dominated by swirl and pumping up the rotating disk.

  4. Nanostructure Formation by controlled dewetting on patterned substrates: A combined theoretical, modeling and experimental study.

    PubMed

    Lu, Liang-Xing; Wang, Ying-Min; Srinivasan, Bharathi Madurai; Asbahi, Mohamed; Yang, Joel K W; Zhang, Yong-Wei

    2016-09-01

    We perform systematic two-dimensional energetic analysis to study the stability of various nanostructures formed by dewetting solid films deposited on patterned substrates. Our analytical results show that by controlling system parameters such as the substrate surface pattern, film thickness and wetting angle, a variety of equilibrium nanostructures can be obtained. Phase diagrams are presented to show the complex relations between these system parameters and various nanostructure morphologies. We further carry out both phase field simulations and dewetting experiments to validate the analytically derived phase diagrams. Good agreements between the results from our energetic analyses and those from our phase field simulations and experiments verify our analysis. Hence, the phase diagrams presented here provide guidelines for using solid-state dewetting as a tool to achieve various nanostructures.

  5. Evolutionary technology adoption in an oligopoly market with forward-looking firms.

    PubMed

    Lamantia, F; Radi, D

    2018-05-01

    In this paper, we propose an evolutionary oligopoly game of technology adoption in a market with isoelastic demand and two possible (linear) production technologies. While one technology is characterized by lower marginal costs, the magnitude of fixed costs entails that a technology does not necessarily dominate the other. Firms are forward-looking as they assess the profitability of employing either technology according to the corresponding expected profits. The dynamics of the system is studied through a piecewise-smooth map, for which we present a local stability analysis of equilibria and show the occurrence of smooth and border collision bifurcations. Global analysis of the model is also presented to show the coexistence of attractors and its economic significance. This investigation reveals that firms can fail to learn to adopt the more efficient technology.

  6. Data on the no-load performance analysis of a tomato postharvest storage system.

    PubMed

    Ayomide, Orhewere B; Ajayi, Oluseyi O; Banjo, Solomon O; Ajayi, Adesola A

    2017-08-01

    In this present investigation, an original and detailed empirical data on the transfer of heat in a tomato postharvest storage system was presented. No-load tests were performed for a period of 96 h. The heat distribution at different locations, namely the top, middle and bottom of the system was acquired, at a time interval of 30 min for the test period. The humidity inside the system was taken into consideration. Thus, No-load tests with or without introduction of humidity were carried out and data showing the effect of a rise in humidity level, on temperature distribution were acquired. The temperatures at the external mechanical cooling components were acquired and could be used for showing the performance analysis of the storage system.

  7. Characterization and classification of oral tissues using excitation and emission matrix: a statistical modeling approach

    NASA Astrophysics Data System (ADS)

    Kanniyappan, Udayakumar; Gnanatheepaminstein, Einstein; Prakasarao, Aruna; Dornadula, Koteeswaran; Singaravelu, Ganesan

    2017-02-01

    Cancer is one of the most common human threats around the world and diagnosis based on optical spectroscopy especially fluorescence technique has been established as the standard approach among scientist to explore the biochemical and morphological changes in tissues. In this regard, the present work aims to extract spectral signatures of the various fluorophores present in oral tissues using parallel factor analysis (PARAFAC). Subsequently, the statistical analysis also to be performed to show its diagnostic potential in distinguishing malignant, premalignant from normal oral tissues. Hence, the present study may lead to the possible and/or alternative tool for oral cancer diagnosis.

  8. Realist Ontology and Natural Processes: A Semantic Tool to Analyze the Presentation of the Osmosis Concept in Science Texts

    ERIC Educational Resources Information Center

    Spinelli Barria, Michele; Morales, Cecilia; Merino, Cristian; Quiroz, Waldo

    2016-01-01

    In this work, we developed an ontological tool, based on the scientific realism of Mario Bunge, for the analysis of the presentation of natural processes in science textbooks. This tool was applied to analyze the presentation of the concept of osmosis in 16 chemistry and biology books at different educational levels. The results showed that more…

  9. Analysis of the quench propagation along Nb3Sn Rutherford cables with the THELMA code. Part I: Geometric and thermal models

    NASA Astrophysics Data System (ADS)

    Manfreda, G.; Bellina, F.

    2016-12-01

    The paper describes the new lumped thermal model recently implemented in THELMA code for the coupled electromagnetic-thermal analysis of superconducting cables. A new geometrical model is also presented, which describes the Rutherford cables used for the accelerator magnets. A first validation of these models has been given by the analysis of the quench longitudinal propagation velocity in the Nb3Sn prototype coil SMC3, built and tested in the frame of the EUCARD project for the development of high field magnets for LHC machine. This paper shows in detail the models, while their application to the quench propagation analysis is presented in a companion paper.

  10. Finite element prediction on the chassis design of UniART4 racing car

    NASA Astrophysics Data System (ADS)

    Zaman, Z. I.; Basaruddin, K. S.; Basha, M. H.; Rahman, M. T. Abd; Daud, R.

    2017-09-01

    This paper presents the analysis and evaluation of the chassis design for University Automotive Racing Team No. 4 (UniART4) car based on finite element analysis. The existing UniART4 car chassis was measured and modelled geometrically using Solidwork before analysed in FEA software (ANSYS). Four types of static structural analysis were used to predict the chassis design capability under four different loading conditions; vertical bending, lateral bending, lateral torsion and horizontal lozenging. The results showed the chassis subjected to the highest stress and strain under horizontal lozenging, whereas the minimum stress and strain response was obtained under lateral bending. The present analysis result could provide valuable information in predicting the sustainability of the current UniART car chassis design.

  11. The CASA Software Package

    NASA Astrophysics Data System (ADS)

    Petry, Dirk

    2018-03-01

    CASA is the standard science data analysis package for ALMA and VLA but it can also be used for the analysis of data from other observatories. In this talk, I will give an overview of the structure and features of CASA, who develops it, and the present status and plans, and then show typical analysis workflows for ALMA data with special emphasis on the handling of single dish data and its combination with interferometric data.

  12. Stress Analysis and Fracture in Nanolaminate Composites

    NASA Technical Reports Server (NTRS)

    Chamis, Christos C.

    2008-01-01

    A stress analysis is performed on a nanolaminate subjected to bending. A composite mechanics computer code that is based on constituent properties and nanoelement formulation is used to evaluate the nanolaminate stresses. The results indicate that the computer code is sufficient for the analysis. The results also show that when a stress concentration is present, the nanolaminate stresses exceed their corresponding matrix-dominated strengths and the nanofiber fracture strength.

  13. Future Integrated Architecture (FIA): A Proposed Space Internetworking Architecture for Future Operations

    DTIC Science & Technology

    2008-09-01

    WiMax “as a ‘last mile’ broadband wireless access (BWA) alternative to cable modem service, telephone company Digital Subscriber Line (DSL) or T1/E1...MUOS at 56k , shows results similar to another simulation with different circuit configurations. Analysis presented in this thesis shows adequate

  14. Fat stigmatization in television shows and movies: a content analysis.

    PubMed

    Himes, Susan M; Thompson, J Kevin

    2007-03-01

    To examine the phenomenon of fat stigmatization messages presented in television shows and movies, a content analysis was used to quantify and categorize fat-specific commentary and humor. Fat stigmatization vignettes were identified using a targeted sampling procedure, and 135 scenes were excised from movies and television shows. The material was coded by trained raters. Reliability indices were uniformly high for the seven categories (percentage agreement ranged from 0.90 to 0.98; kappas ranged from 0.66 to 0.94). Results indicated that fat stigmatization commentary and fat humor were often verbal, directed toward another person, and often presented directly in the presence of the overweight target. Results also indicated that male characters were three times more likely to engage in fat stigmatization commentary or fat humor than female characters. To our knowledge, these findings provide the first information regarding the specific gender, age, and types of fat stigmatization that occur frequently in movies and television shows. The stimuli should prove useful in future research examining the role of individual difference factors (e.g., BMI) in the reaction to viewing such vignettes.

  15. The Role of Human Web Assistants in E-Commerce: An Analysis and a Usability Study.

    ERIC Educational Resources Information Center

    Aberg, Johan; Shahmehri, Nahid

    2000-01-01

    Discusses electronic commerce and presents the concept of Web assistants, human assistants working in an electronic Web shop. Presents results of a usability study of a prototype adaptive Web assistant system that show users were enthusiastic about the concept of Web assistants and its implications. (Author/LRW)

  16. Cytocompatibility, cytotoxicity and genotoxicity analysis of dental implants

    NASA Astrophysics Data System (ADS)

    Reigosa, M.; Labarta, V.; Molinari, G.; Bernales, D.

    2007-11-01

    Several types of materials are frequently used for dental prostheses in dental medicine. Different treatments with titanium are the most used. The aim of the present study was to analyze by means of cytotoxicity and cytocompatibility techniques the capacity of dental implants to integrate to the bone tissue. Cultures of UMR 106 cell line derived from an osteosarcoma were used for bioassays mainly because they show many of the properties of osteoblasts. Dental implant samples provided by B&W company were compared with others of recognized trademarks. The first ones contain ASTM titanium (8348 GR2) with acid printing. Cytotoxicity was analyzed by means of lysosome activity, using the neutral red technique and alkaline phosphatase enzyme activity. Cell variability was determined by means of the acridine ethidium-orange bromide technique. One-way ANOVA and Bonferroni and Duncan post-ANOVA tests were used for the statistical analysis. The assays did not show significant differences among the dental implants analyzed. Our findings show that the dental prostheses studied present high biocompatibility, quantified by the bioassays performed. The techniques employed revealed that they can be a useful tool for the analysis of other materials for dental medicine use.

  17. [Development and equivalence evaluation of spondee lists of mandarin speech test materials].

    PubMed

    Zhang, Hua; Wang, Shuo; Wang, Liang; Chen, Jing; Chen, Ai-ting; Guo, Lian-sheng; Zhao, Xiao-yan; Ji, Chen

    2006-06-01

    To edit the spondee (disyllable) word lists as a part of mandarin speech test materials (MSTM). These will be basic speech materials for routine tests in clinics and laboratories. Two groups of professionals (audiologists, Chinese and Mandarin scientists, linguistician and statistician) were set up at first. The editing principles were established after 3 round table meetings. Ten spondee lists, each with 50 words, were edited and recorded into cassettes. All lists were phonemically balanced (3-dimensions: vowels, consonants and Chinese tones). Seventy-three normal hearing college students were tested. The speech was presented by earphone monaurally. Three statistic methods were used for equivalent analysis. Related analysis showed that all lists were much related, except List 5. Cluster analysis showed that all ten lists could be classified as two groups. But Kappa test showed that the lists' homogeneity were not well. Spondee lists are one of the most routine speech test materials. Their editing, recording and equivalent evaluation are affected by many factors. This also needs multi-discipline cooperation. All lists edited in present study need future modification in recording and testing in order to be used clinically and in research. The phonemic balance should be kept.

  18. Correlation between thermal behavior of clays and their chemical and mineralogical composition: a review

    NASA Astrophysics Data System (ADS)

    Dwi Yanti, Evi; Pratiwi, I.

    2018-02-01

    Clay's abundance has been widely used as industrial raw materials, especially ceramic and tile industries. Utilization of these minerals needs a thermal process for producing ceramic products. Two studies conducted by Septawander et al. and Chin C et al., showed the relationship between thermal behavior of clays and their chemical and mineralogical composition. Clays are characterized by XRD analysis and thermal analysis, ranging from 1100°C to 1200°C room temperature. Specimen of raw materials of clay which is used for the thermal treatment is taken from different geological conditions and formation. In raw material, Quartz is almost present in all samples. Halloysite, montmorillonite, and feldspar are present in Tanjung Morawa raw clay. KC and MC similar kaolinite and illite are present in the samples. The research illustrates the interrelationships of clay minerals and chemical composition with their heat behavior. As the temperature of combustion increases, the sample reduces a significant weight. The minerals which have undergone a transformation phase became mullite, cristobalite or illite and quartz. Under SEM analysis, the microstructures of the samples showed irregularity in shape; changes occurred due the increase of heat.

  19. Analysis and modification of theory for impact of seaplanes on water

    NASA Technical Reports Server (NTRS)

    Mayo, Wilbur L

    1945-01-01

    An analysis of available theory on seaplane impact and a proposed modification thereto are presented. In previous methods the overall momentum of the float and virtual mass has been assumed to remain constant during the impact but the present analysis shows that this assumption is rigorously correct only when the resultant velocity of the float is normal to the keel. The proposed modification chiefly involves consideration of the fact that forward velocity of the seaplane float causes momentum to be passed into the hydrodynamic downwash (an action that is the entire consideration in the case of the planing float) and consideration of the fact that, for an impact with trim, the rate of penetration is determined not only by the velocity component normal to the keel but also by the velocity component parallel to the keel, which tends to reduce the penetration. Experimental data for planing, oblique impact, and vertical drop are used to show that the accuracy of the proposed theory is good.

  20. Integrating Household Risk Mitigation Behavior in Flood Risk Analysis: An Agent-Based Model Approach.

    PubMed

    Haer, Toon; Botzen, W J Wouter; de Moel, Hans; Aerts, Jeroen C J H

    2017-10-01

    Recent studies showed that climate change and socioeconomic trends are expected to increase flood risks in many regions. However, in these studies, human behavior is commonly assumed to be constant, which neglects interaction and feedback loops between human and environmental systems. This neglect of human adaptation leads to a misrepresentation of flood risk. This article presents an agent-based model that incorporates human decision making in flood risk analysis. In particular, household investments in loss-reducing measures are examined under three economic decision models: (1) expected utility theory, which is the traditional economic model of rational agents; (2) prospect theory, which takes account of bounded rationality; and (3) a prospect theory model, which accounts for changing risk perceptions and social interactions through a process of Bayesian updating. We show that neglecting human behavior in flood risk assessment studies can result in a considerable misestimation of future flood risk, which is in our case study an overestimation of a factor two. Furthermore, we show how behavior models can support flood risk analysis under different behavioral assumptions, illustrating the need to include the dynamic adaptive human behavior of, for instance, households, insurers, and governments. The method presented here provides a solid basis for exploring human behavior and the resulting flood risk with respect to low-probability/high-impact risks. © 2016 The Authors Risk Analysis published by Wiley Periodicals, Inc. on behalf of Society for Risk Analysis.

  1. Photodegradation of crude oil: liquid injection and headspace solid-phase microextraction for crude oil analysis by gas chromatography with mass spectrometer detector.

    PubMed

    D'Auria, Maurizio; Racioppi, Rocco; Velluzzi, Vincenzina

    2008-04-01

    The fate of crude oil under irradiation is studied. After UV irradiation, the fraction present in the highest percentage shifts from the C8-C9 fractions to C13, using gas chromatography-mass spectrometry (GC-MS) analysis in solution. An increase of the relative amount of the C13-C25 fraction is observed, while a decrease in the relative amount of the C7-C12 fractions is present. In headspace solid-phase microextraction (HS-SPME) analysis, the C8-C10 fractions represent 53% of all the compounds detected. A decrease in the relative amount of the C8-C10 fractions is observed, while C11-C15 fractions increase. The irradiation of crude oil with a solar simulator gives a mixture the analysis of which using GC-MS in solution furnishes the same type of results: the relative amounts of linear alkanes and aromatic compounds increase, while a sharp decrease in the relative amounts of branched and cyclic alkanes is observed. In the SPME analysis, a decreased relative amount of branched alkanes and alkenes, and an increase in the relative amounts of cyclic alkanes and aromatic compounds are observed. Analysis of the distribution of the compounds in all the types of compound shows that a dynamic equilibrium between different compounds and different types of compounds is present. To confirm the presence of a dynamic equilibrium, the irradiation of methylcyclohexane in the presence of 2-methylnaphthalene shows the presence in the reaction mixture of a small amount of tetradecane.

  2. Analysis of the vibrational frequencies of the UO/sup 2 +//sub 2/ ion in complexes containing acido-ligands

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kobets, L.V.; Umreiko, D.S.

    1986-02-01

    This paper presents an analysis of the vibrational frequencies of the UO/sup 2 +//sub 2/ ion in its complexes with acido-ligands that shows that in the series of the compounds indicated the correlation of UO/sup 2 +//sub 2/ with the nature of the anions and in particular with their basicity is limited in nature and may not be considered without taking account of the specific structures. If neutral ligands are present in the complexes, the situation is probably even more complicated.

  3. Simplified fatigue life analysis for traction drive contacts

    NASA Technical Reports Server (NTRS)

    Rohn, D. A.; Loewenthal, S. H.; Coy, J. J.

    1980-01-01

    A simplified fatigue life analysis for traction drive contacts of arbitrary geometry is presented. The analysis is based on the Lundberg-Palmgren theory used for rolling-element bearings. The effects of torque, element size, speed, contact ellipse ratio, and the influence of traction coefficient are shown. The analysis shows that within the limits of the available traction coefficient, traction contacts exhibit longest life at high speeds. Multiple, load-sharing roller arrangements have an advantageous effect on system life, torque capacity, power-to-weight ratio and size.

  4. Organellar Genomes from a ∼5,000-Year-Old Archaeological Maize Sample Are Closely Related to NB Genotype

    PubMed Central

    Pérez-Zamorano, Bernardo; Vallebueno-Estrada, Miguel; Martínez González, Javier; García Cook, Angel; Montiel, Rafael; Vielle-Calzada, Jean-Philippe

    2017-01-01

    The story of how preColumbian civilizations developed goes hand-in-hand with the process of plant domestication by Mesoamerican inhabitants. Here, we present the almost complete sequence of a mitochondrial genome and a partial chloroplast genome from an archaeological maize sample collected at the Valley of Tehuacán, México. Accelerator mass spectrometry dated the maize sample to be 5,040–5,300 years before present (95% probability). Phylogenetic analysis of the mitochondrial genome shows that the archaeological sample branches basal to the other Zea mays genomes, as expected. However, this analysis also indicates that fertile genotype NB is closely related to the archaeological maize sample and evolved before cytoplasmic male sterility genotypes (CMS-S, CMS-T, and CMS-C), thus contradicting previous phylogenetic analysis of mitochondrial genomes from maize. We show that maximum-likelihood infers a tree where CMS genotypes branch at the base of the tree when including sites that have a relative fast rate of evolution thus suggesting long-branch attraction. We also show that Bayesian analysis infer a topology where NB and the archaeological maize sample are at the base of the tree even when including faster sites. We therefore suggest that previous trees suffered from long-branch attraction. We also show that the phylogenetic analysis of the ancient chloroplast is congruent with genotype NB to be more closely related to the archaeological maize sample. As shown here, the inclusion of ancient genomes on phylogenetic trees greatly improves our understanding of the domestication process of maize, one of the most important crops worldwide. PMID:28338960

  5. Adaptation of an urban land surface model to a tropical suburban area: Offline evaluation, sensitivity analysis, and optimization of TEB/ISBA (SURFEX)

    NASA Astrophysics Data System (ADS)

    Harshan, Suraj

    The main objective of the present thesis is the improvement of the TEB/ISBA (SURFEX) urban land surface model (ULSM) through comprehensive evaluation, sensitivity analysis, and optimization experiments using energy balance and radiative and air temperature data observed during 11 months at a tropical sub-urban site in Singapore. Overall the performance of the model is satisfactory, with a small underestimation of net radiation and an overestimation of sensible heat flux. Weaknesses in predicting the latent heat flux are apparent with smaller model values during daytime and the model also significantly underpredicts both the daytime peak and nighttime storage heat. Surface temperatures of all facets are generally overpredicted. Significant variation exists in the model behaviour between dry and wet seasons. The vegetation parametrization used in the model is inadequate to represent the moisture dynamics, producing unrealistically low latent heat fluxes during a particularly dry period. The comprehensive evaluation of the USLM shows the need for accurate estimation of input parameter values for present site. Since obtaining many of these parameters through empirical methods is not feasible, the present study employed a two step approach aimed at providing information about the most sensitive parameters and an optimized parameter set from model calibration. Two well established sensitivity analysis methods (global: Sobol and local: Morris) and a state-of-the-art multiobjective evolutionary algorithm (Borg) were employed for sensitivity analysis and parameter estimation. Experiments were carried out for three different weather periods. The analysis indicates that roof related parameters are the most important ones in controlling the behaviour of the sensible heat flux and net radiation flux, with roof and road albedo as the most influential parameters. Soil moisture initialization parameters are important in controlling the latent heat flux. The built (town) fraction has a significant influence on all fluxes considered. Comparison between the Sobol and Morris methods shows similar sensitivities, indicating the robustness of the present analysis and that the Morris method can be employed as a computationally cheaper alternative of Sobol's method. Optimization as well as the sensitivity experiments for the three periods (dry, wet and mixed), show a noticeable difference in parameter sensitivity and parameter convergence, indicating inadequacies in model formulation. Existence of a significant proportion of less sensitive parameters might be indicating an over-parametrized model. Borg MOEA showed great promise in optimizing the input parameters set. The optimized model modified using the site specific values for thermal roughness length parametrization shows an improvement in the performances of outgoing longwave radiation flux, overall surface temperature, heat storage flux and sensible heat flux.

  6. Is a Clean Development Mechanism project economically justified? Case study of an International Carbon Sequestration Project in Iran.

    PubMed

    Katircioglu, Salih; Dalir, Sara; Olya, Hossein G

    2016-01-01

    The present study evaluates a carbon sequestration project for the three plant species in arid and semiarid regions of Iran. Results show that Haloxylon performed appropriately in the carbon sequestration process during the 6 years of the International Carbon Sequestration Project (ICSP). In addition to a high degree of carbon dioxide sequestration, Haloxylon shows high compatibility with severe environmental conditions and low maintenance costs. Financial and economic analysis demonstrated that the ICSP was justified from an economic perspective. The financial assessment showed that net present value (NPV) (US$1,098,022.70), internal rate of return (IRR) (21.53%), and payback period (6 years) were in an acceptable range. The results of the economic analysis suggested an NPV of US$4,407,805.15 and an IRR of 50.63%. Therefore, results of this study suggest that there are sufficient incentives for investors to participate in such kind of Clean Development Mechanism (CDM) projects.

  7. Deriving the solar activity cycle modulation on cosmic ray intensity observed by Nagoya muon detector from October 1970 until December 2012

    NASA Astrophysics Data System (ADS)

    de Mendonça, Rafael R. S.; Braga, Carlos. R.; Echer, Ezequiel; Dal Lago, Alisson; Rockenbach, Marlos; Schuch, Nelson J.; Munakata, Kazuoki

    2017-10-01

    It is well known that the cosmic ray intensity observed at the Earth's surface presents an 11 and 22-yr variations associated with the solar activity cycle. However, the observation and analysis of this modulation through ground muon detectors datahave been difficult due to the temperature effect. Furthermore, instrumental changes or temporary problems may difficult the analysis of these variations. In this work, we analyze the cosmic ray intensity observed since October 1970 until December 2012 by the Nagoya muon detector. We show the results obtained after analyzing all discontinuities and gaps present in this data and removing changes not related to natural phenomena. We also show the results found using the mass weighted method for eliminate the influence of atmospheric temperature changes on muon intensity observed at ground. As a preliminary result of our analyses, we show the solar cycle modulation in the muon intensity observed for more than 40 years.

  8. Cytotaxonomy of two species of genus Chrysolaena H. Robinson, 1988 (Vernonieae, Asteraceae) from Northeast Paraguay

    PubMed Central

    Pico, Gisela M. Via Do; Dematteis, Massimiliano

    2014-01-01

    Abstract Chromosome counts and karyotypes of two species of Chrysolaena H. Robinson 1988 are presented in this paper. Mitotic analysis revealed that both taxa have x=10, a basic chromosome number considered characteristic of the genus. The chromosome number and the karyotype of Chrysolaena cristobaliana are reported for the first time, as well as a new cytotype and the karyotype of Chrysolaena sceptrum. Chrysolaena cristobaliana showed heptaploid cytotype with 2n=7x=70 and a karyotype composed of 46 m + 24 sm chromosomes. On the other hand, Chrysolaena sceptrum presented tetraploid cytotype with 2n=4x=40 and a karyotype with 30 m + 10 sm chromosomes. Accessory chromosomes were observed in cells of both species. The chromosome analysis showed that these species differ in the chromosome number and the total chromosome length, although they showed similar chromosome morphology and asymmetry indexes. The results support the use of chromosome data in taxonomic treatments of the American members of the tribe Vernonieae. PMID:25147624

  9. Constraints based analysis of extended cybernetic models.

    PubMed

    Mandli, Aravinda R; Venkatesh, Kareenhalli V; Modak, Jayant M

    2015-11-01

    The cybernetic modeling framework provides an interesting approach to model the regulatory phenomena occurring in microorganisms. In the present work, we adopt a constraints based approach to analyze the nonlinear behavior of the extended equations of the cybernetic model. We first show that the cybernetic model exhibits linear growth behavior under the constraint of no resource allocation for the induction of the key enzyme. We then quantify the maximum achievable specific growth rate of microorganisms on mixtures of substitutable substrates under various kinds of regulation and show its use in gaining an understanding of the regulatory strategies of microorganisms. Finally, we show that Saccharomyces cerevisiae exhibits suboptimal dynamic growth with a long diauxic lag phase when growing on a mixture of glucose and galactose and discuss on its potential to achieve optimal growth with a significantly reduced diauxic lag period. The analysis carried out in the present study illustrates the utility of adopting a constraints based approach to understand the dynamic growth strategies of microorganisms. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  10. Analysis of laser printer and photocopier toners by spectral properties and chemometrics

    NASA Astrophysics Data System (ADS)

    Verma, Neha; Kumar, Raj; Sharma, Vishal

    2018-05-01

    The use of printers to generate falsified documents has become a common practice in today's world. The examination and identification of the printed matter in the suspected documents (civil or criminal cases) may provide important information about the authenticity of the document. In the present study, a total number of 100 black toner samples both from laser printers and photocopiers were examined using diffuse reflectance UV-Vis Spectroscopy. The present research is divided into two parts; visual discrimination and discrimination by using multivariate analysis. A comparison between qualitative and quantitative analysis showed that multivariate analysis (Principal component analysis) provides 99.59%pair-wise discriminating power for laser printer toners while 99.84% pair-wise discriminating power for photocopier toners. The overall results obtained confirm the applicability of UV-Vis spectroscopy and chemometrics, in the nondestructive analysis of toner printed documents while enhancing their evidential value for forensic applications.

  11. An Analysis of the Connectedness to Nature Scale Based on Item Response Theory

    PubMed Central

    Pasca, Laura; Aragonés, Juan I.; Coello, María T.

    2017-01-01

    The Connectedness to Nature Scale (CNS) is used as a measure of the subjective cognitive connection between individuals and nature. However, to date, it has not been analyzed at the item level to confirm its quality. In the present study, we conduct such an analysis based on Item Response Theory. We employed data from previous studies using the Spanish-language version of the CNS, analyzing a sample of 1008 participants. The results show that seven items presented appropriate indices of discrimination and difficulty, in addition to a good fit. The remaining six have inadequate discrimination indices and do not present a good fit. A second study with 321 participants shows that the seven-item scale has adequate levels of reliability and validity. Therefore, it would be appropriate to use a reduced version of the scale after eliminating the items that display inappropriate behavior, since they may interfere with research results on connectedness to nature. PMID:28824509

  12. Does Money Matter? A Meta-Analysis of Studies of the Effects of Differential School Inputs on Student Outcomes. (An Exchange: Part 1).

    ERIC Educational Resources Information Center

    Hedges, Larry V.; And Others

    1994-01-01

    Presents reanalysis of data from earlier reviews, particularly those by Hanushek (1981, 1986, 1989, 1991), on relationship between educational resource input and school outcomes when controlling for student characteristics such as socioeconomic status. Using different synthesis methods, analysis shows a positive relationship between resources and…

  13. Forest Inventory and Analysis and Forest Health Monitoring: Piecing the Quilt

    Treesearch

    Joseph M. McCollum; Jamie K. Cochran

    2005-01-01

    Against the backdrop of a discussion about patchwork quilt assembly, the authors present background information on global grids. They show how to compose hexagons, an important task in systematically developing a subset of Forest Health Monitoring (FHM) Program plots from Forest Inventory and Analysis (FIA) plots. Finally, they outline the FHM and FIA grids, along with...

  14. THE CONTEXTUAL ANALYSIS OF SYMBOLISM IN LANGUAGE.

    ERIC Educational Resources Information Center

    LAFFAL, JULIUS

    A TECHNIQUE OF ANALYSIS OF SYMBOLISM IS PRESENTED, BASED ON THE IDEA THAT WORDS WHICH APPEAR IN CLOSE ASSOCIATION IN THE SPEECH OR WRITING OF AN INDIVIDUAL ARE PSYCHOLOGICALLY CLOSELY RELATED. THE LATENT MEANING, OR SYMBOLISM, OF A WORD IS ELUCIDATED BY SHOWING HOW CLOSE IT IS, CONCEPTUALLY, TO OTHER SELECTED WORDS OR THEMES IN THE INDIVIDUAL'S…

  15. Mars Rock Analysis Briefing

    NASA Image and Video Library

    2013-03-12

    David Blake, principal investigator for Curiosity's Chemistry and Mineralogy investigation at NASA's Ames Research Center in Calif., speaks at a news conference presenting findings of the Curiosity rover's analysis of the first sample of rock powder collected on Mars, Tuesday, March 12, 2013 in Washington. The rock sample collected shows ancient Mars could have supported living microbes. Photo Credit: (NASA/Carla Cioffi)

  16. Is It Necessary to Dry Primary Standards before Analysis?

    ERIC Educational Resources Information Center

    Spraggins, Jeffrey M., II; Williams, Theodore R.

    2005-01-01

    The thermal gravimetric analysis (TGA) data suggests that the quantity of volatile components in primary standards is less than 1% of the initial weight and differential scanning calorimetry (DSC) data shows that water present in the same chemicals is below the limit of detection of the instrumentation. This suggests that the 1-2 hour drying…

  17. Novel Image Encryption Scheme Based on Chebyshev Polynomial and Duffing Map

    PubMed Central

    2014-01-01

    We present a novel image encryption algorithm using Chebyshev polynomial based on permutation and substitution and Duffing map based on substitution. Comprehensive security analysis has been performed on the designed scheme using key space analysis, visual testing, histogram analysis, information entropy calculation, correlation coefficient analysis, differential analysis, key sensitivity test, and speed test. The study demonstrates that the proposed image encryption algorithm shows advantages of more than 10113 key space and desirable level of security based on the good statistical results and theoretical arguments. PMID:25143970

  18. Aspects of oral communication in patients with Parkinson's disease submitted to Deep Brain Stimulation.

    PubMed

    Cruz, Aline Nunes da; Beber, Bárbara Costa; Olchik, Maira Rozenfeld; Chaves, Márcia Lorena Fagundes; Rieder, Carlos Roberto de Mello; Dornelles, Sílvia

    2016-01-01

    Deep Brain Stimulation (DBS) has been satisfactorily used to control the cardinal motor symptoms of Parkinson's disease (PD), but little is known about its impact on communication. This study aimed to characterize the aspects of cognition, language, speech, voice, and self-perception in two patients with PD, pre- and post- DBS implant surgery. The patients were assessed using a cognitive screening test, a brief language evaluation, a self-declared protocol, and an analysis of the aspects of voice and speech, which was conducted by a specialized Speech-language Therapist who was blinded for the study. At the pre-surgery assessment, Case I showed impairment regarding the aspects of cognition, language and voice, whereas Case II showed impairment only with respect to the voice aspect. The post-surgery evaluation of the cases showed an opposite pattern of the effect of DBS after analysis of the communication data: Case I, who presented greater impairment before the surgery, showed improvement in some aspects; Case II, who presented lower communicative impairment before the surgery, showed worsening in other aspects. This study shows that DBS may influence different communication aspects both positively and negatively. Factors associated with the different effects caused by DBS on the communication of patients with PD need to be further investigated.

  19. Using Data Analysis to Explore Class Enrollment.

    ERIC Educational Resources Information Center

    Davis, Gretchen

    1990-01-01

    Describes classroom activities and shows that statistics is a practical tool for solving real problems. Presents a histogram, a stem plot, and a box plot to compare data involving class enrollments. (YP)

  20. Flutter Research on Skin Panels

    NASA Technical Reports Server (NTRS)

    Kordes, Eldon E.; Tuovila, Weimer J.; Guy, Lawrence D.

    1960-01-01

    Representative experimental results are presented to show the current status of the panel flutter problem. Results are presented for unstiffened rectangular panels and for rectangular panels stiffened by corrugated backing. Flutter boundaries are established for all types of panels when considered on the basis of equivalent isotropic plates. The effects of Mach number, differential pressure, and aerodynamic heating on panel flutter are discussed. A flutter analysis of orthotropic panels is presented in the appendix.

  1. Accuracy and Precision of Silicon Based Impression Media for Quantitative Areal Texture Analysis

    PubMed Central

    Goodall, Robert H.; Darras, Laurent P.; Purnell, Mark A.

    2015-01-01

    Areal surface texture analysis is becoming widespread across a diverse range of applications, from engineering to ecology. In many studies silicon based impression media are used to replicate surfaces, and the fidelity of replication defines the quality of data collected. However, while different investigators have used different impression media, the fidelity of surface replication has not been subjected to quantitative analysis based on areal texture data. Here we present the results of an analysis of the accuracy and precision with which different silicon based impression media of varying composition and viscosity replicate rough and smooth surfaces. Both accuracy and precision vary greatly between different media. High viscosity media tested show very low accuracy and precision, and most other compounds showed either the same pattern, or low accuracy and high precision, or low precision and high accuracy. Of the media tested, mid viscosity President Jet Regular Body and low viscosity President Jet Light Body (Coltène Whaledent) are the only compounds to show high levels of accuracy and precision on both surface types. Our results show that data acquired from different impression media are not comparable, supporting calls for greater standardisation of methods in areal texture analysis. PMID:25991505

  2. A concept for holistic whole body MRI data analysis, Imiomics

    PubMed Central

    Malmberg, Filip; Johansson, Lars; Lind, Lars; Sundbom, Magnus; Ahlström, Håkan; Kullberg, Joel

    2017-01-01

    Purpose To present and evaluate a whole-body image analysis concept, Imiomics (imaging–omics) and an image registration method that enables Imiomics analyses by deforming all image data to a common coordinate system, so that the information in each voxel can be compared between persons or within a person over time and integrated with non-imaging data. Methods The presented image registration method utilizes relative elasticity constraints of different tissue obtained from whole-body water-fat MRI. The registration method is evaluated by inverse consistency and Dice coefficients and the Imiomics concept is evaluated by example analyses of importance for metabolic research using non-imaging parameters where we know what to expect. The example analyses include whole body imaging atlas creation, anomaly detection, and cross-sectional and longitudinal analysis. Results The image registration method evaluation on 128 subjects shows low inverse consistency errors and high Dice coefficients. Also, the statistical atlas with fat content intensity values shows low standard deviation values, indicating successful deformations to the common coordinate system. The example analyses show expected associations and correlations which agree with explicit measurements, and thereby illustrate the usefulness of the proposed Imiomics concept. Conclusions The registration method is well-suited for Imiomics analyses, which enable analyses of relationships to non-imaging data, e.g. clinical data, in new types of holistic targeted and untargeted big-data analysis. PMID:28241015

  3. Bladed wheels damage detection through Non-Harmonic Fourier Analysis improved algorithm

    NASA Astrophysics Data System (ADS)

    Neri, P.

    2017-05-01

    Recent papers introduced the Non-Harmonic Fourier Analysis for bladed wheels damage detection. This technique showed its potential in estimating the frequency of sinusoidal signals even when the acquisition time is short with respect to the vibration period, provided that some hypothesis are fulfilled. Anyway, previously proposed algorithms showed severe limitations in cracks detection at their early stage. The present paper proposes an improved algorithm which allows to detect a blade vibration frequency shift due to a crack whose size is really small compared to the blade width. Such a technique could be implemented for condition-based maintenance, allowing to use non-contact methods for vibration measurements. A stator-fixed laser sensor could monitor all the blades as they pass in front of the spot, giving precious information about the wheel health. This configuration determines an acquisition time for each blade which become shorter as the machine rotational speed increases. In this situation, traditional Discrete Fourier Transform analysis results in poor frequency resolution, being not suitable for small frequency shift detection. Non-Harmonic Fourier Analysis instead showed high reliability in vibration frequency estimation even with data samples collected in a short time range. A description of the improved algorithm is provided in the paper, along with a comparison with the previous one. Finally, a validation of the method is presented, based on finite element simulations results.

  4. Response of well aquifer systems to Earth tides: Problem revisited

    USGS Publications Warehouse

    Hsieh, Paul A.; Bredehoeft, John D.; Rojstaczer, Stuart

    1988-01-01

    Two recent works cause us to reexamine Bredehoeft's (1967) analysis of earthtide response of water wells. Narasimhan et al. (1984) raise several questions regarding Bredehoeft's (1967) analysis and suggest that the analysis is internally inconsistent. They argue that one cannot directly estimate the specific storage, which characterizes the drained behavior of a porous medium, from earth tide response, which is an undrained phenomenon. We resolve the questions raised by Narasimhan et al. (1984) and show that Bredehoeft's analysis is internally consistent. In addition, we show that it is possible to determine the specific storage from undrained loading. While Bredehoeft's analysis is somewhat heuristic and neglects grain compressibility, Van der Kamp and Gale (1983) present a more rigorous analysis that is based on Biot's (1941) constitutive relationships and accounts for grain compressibility. However, their results reduce to Bredehoeft's results when grains are assumed incompressible. This suggests that Bredehoeft's analysis has incorporated all the essential features of Biot's relationships except for grain compressibility. Upon reexamining Bredehoeft's analysis we find that this is indeed the case.

  5. Component analysis of Iranian crack; a newly abused narcotic substance in iran.

    PubMed

    Farhoudian, Ali; Sadeghi, Mandana; Khoddami Vishteh, Hamid Reza; Moazen, Babak; Fekri, Monir; Rahimi Movaghar, Afarin

    2014-01-01

    Iranian crack is a new form of narcotic substance that has found widespread prevalence in Iran in the past years. Crack only nominally resembles crack cocaine as it is widely different in its clinical signs. Thus the present study aims to quantify the chemical combination of this drug. The samples included 18 specimen of Crack collected from different zones of Tehran, Iran. All specimens were in the form of inodorous cream solid powdery substance. TLC and HPLC methods were used to perform semi-quantitative and quantitative analysis of the components, respectively. The TLC analysis showed no cocaine compound in the specimens while they all revealed to contain heroin, codeine, morphine and caffeine. All but two specimens contained thebaine. None of the specimens contained amphetamine, benzodiazepines, tricyclic antidepressants, aspirin, barbiturates, tramadol and buprenorphine. Acetaminophen was found in four specimens. HPLC revealed heroin to be the foundation substance in all specimens and most of them contained a significant amount of acetylcodeine. The present analysis of the chemical combination of Crack showed that this substance is a heroin-based narcotic which is basically different from the cocaine-based crack used in Western countries. Studies like the present one at different time points, especially when abnormal clinical signs are detected, can reveal the chemical combination of the target substance and contribute to the clinical management of its acute or chronic poisoning.

  6. Bounded Linear Stability Margin Analysis of Nonlinear Hybrid Adaptive Control

    NASA Technical Reports Server (NTRS)

    Nguyen, Nhan T.; Boskovic, Jovan D.

    2008-01-01

    This paper presents a bounded linear stability analysis for a hybrid adaptive control that blends both direct and indirect adaptive control. Stability and convergence of nonlinear adaptive control are analyzed using an approximate linear equivalent system. A stability margin analysis shows that a large adaptive gain can lead to a reduced phase margin. This method can enable metrics-driven adaptive control whereby the adaptive gain is adjusted to meet stability margin requirements.

  7. Comparison of two computer codes for crack growth analysis: NASCRAC Versus NASA/FLAGRO

    NASA Technical Reports Server (NTRS)

    Stallworth, R.; Meyers, C. A.; Stinson, H. C.

    1989-01-01

    Results are presented from the comparison study of two computer codes for crack growth analysis - NASCRAC and NASA/FLAGRO. The two computer codes gave compatible conservative results when the part through crack analysis solutions were analyzed versus experimental test data. Results showed good correlation between the codes for the through crack at a lug solution. For the through crack at a lug solution, NASA/FLAGRO gave the most conservative results.

  8. Analysis of the internal anatomy of maxillary first molars by using different methods.

    PubMed

    Baratto Filho, Flares; Zaitter, Suellen; Haragushiku, Gisele Aihara; de Campos, Edson Alves; Abuabara, Allan; Correr, Gisele Maria

    2009-03-01

    The success of endodontic treatment depends on the identification of all root canals so that they can be cleaned, shaped, and obturated. This study investigated internal morphology of maxillary first molars by 3 different methods: ex vivo, clinical, and cone beam computed tomography (CBCT) analysis. In all these different methods, the number of additional root canals and their locations, the number of foramina, and the frequency of canals that could or could not be negotiated were recorded. In the ex vivo study, 140 extracted maxillary first molars were evaluated. After canals were accessed and detected by using an operating microscope, the teeth with significant anatomic variances were cleared. In the clinical analysis, the records of 291 patients who had undergone endodontic treatment in a dental school during a 2-year period were used. In the CBCT analysis, 54 maxillary first molars were evaluated. The ex vivo assessment results showed a fourth canal frequency in 67.14% of the teeth, besides a tooth with 7 root canals (0.72%). Additional root canals were located in the mesiobuccal root in 92.85% of the teeth (17.35% could not be negotiated), and when they were present, 65.30% exhibited 1 foramen. Clinical assessment showed that 53.26%, 0.35%, and 0.35% of the teeth exhibited 4, 5, and 6 root canals, respectively. Additional root canals were located in this assessment in mesiobuccal root in 95.63% (27.50% could not be negotiated), and when they were present, 59.38% exhibited 1 foramen. CBCT results showed 2, 4, and 5 root canals in 1.85%, 37.05%, and 1.85% of the teeth, respectively. When present, additional canals showed 1 foramen in 90.90% of the teeth studied. This study demonstrated that operating microscope and CBCT have been important for locating and identifying root canals, and CBCT can be used as a good method for initial identification of maxillary first molar internal morphology.

  9. A Case of Loeffler Endocarditis That Showed Endomyocardial Systolic Dysfunction Detected by Layer Specific Strain Analysis.

    PubMed

    Jin, Xuanyi; Ma, Chunyan; Wang, Yonghuai; Yang, Jun

    2017-12-12

    Loeffler endocarditis is a rare comprehensive cardiac manifestation caused by eosinophilic cell infiltrations and is present in 50%-60% of patients with hypereosinophilic syndrome (HES). Left ventricle (LV) endocardial systolic dysfunction is a major cause of morbidity and mortality in HES and Loeffler endocarditis. We present a case of Loeffler endocarditis, whose left ventricular (LV) systolic dysfunction and endocardial systolic dysfunction were first neglected by conventional transthoracic echocardiography (TTE), but were later pointed out by layer-specific longitudinal strain analysis. With timely initial therapeutic management, the patient's outcome was remarkable. Thus, we strongly recommend strain analysis as a necessary supplementary test of conventional TTE in all patients with Loeffler endocarditis.

  10. Evolutionary and polymorphism analyses reveal the central role of BTN3A2 in the concerted evolution of the BTN3 gene family.

    PubMed

    Afrache, Hassnae; Pontarotti, Pierre; Abi-Rached, Laurent; Olive, Daniel

    2017-06-01

    The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. In order to understand how these genes have been diversified, we studied their evolution and show that the three human BTN3 are the result of two successive duplications in Primates and that the three genes are present in Hominoids and the Old World Monkey groups. A thorough phylogenetic analysis reveals a concerted evolution of BTN3 characterized by a strong and recurrent homogenization of the region encoding the signal peptide and the immunoglobulin variable (IgV) domain in Hominoids, where the sequences of BTN3A1 or BTN3A3 are replaced by BTN3A2 sequence. In human, the analysis of the diversity of these genes in 1683 individuals representing 26 worldwide populations shows that the three genes are polymorphic, with more than 46 alleles for each gene, and marked by extreme homogenization of the IgV sequences. The same analysis performed for the BTN2 genes shows also a concerted evolution; however, it is not as strong and recurrent as for BTN3. This study shows that BTN3 receptors are marked by extreme concerted evolution at the IgV domain and that BTN3A2 plays a central role in this evolution.

  11. A network of automatic atmospherics analyzer

    NASA Technical Reports Server (NTRS)

    Schaefer, J.; Volland, H.; Ingmann, P.; Eriksson, A. J.; Heydt, G.

    1980-01-01

    The design and function of an atmospheric analyzer which uses a computer are discussed. Mathematical models which show the method of measurement are presented. The data analysis and recording procedures of the analyzer are discussed.

  12. Collection Evaluation and Evolution

    NASA Technical Reports Server (NTRS)

    Habermann, Ted; Kozimor, John

    2017-01-01

    We will review metadata evaluation tools and share results from our most recent CMR analysis. We will demonstrate results using Google spreadsheets and present new results in terms of number of records that include specific content. We will show evolution of UMM-compliance over time and also show results of comparing various CMR collections (NASA, non-NASA, and SciOps).

  13. Will Choice Hurt? Compared to What? A School Choice Experiment in Estonia

    ERIC Educational Resources Information Center

    Põder, Kaire; Lauri, Triin

    2014-01-01

    This article presents the empirical analysis of the effects of a school choice policy in Estonia. The article shows that relying on markets and giving autonomy to the schools over student selection will produce admission tests, even at the elementary school level. This article's contribution is to show that a school choice policy experiment with…

  14. Television's Professional Women: Working with Men in the 1980s.

    ERIC Educational Resources Information Center

    Reep, Diana C.; Dambrot, Faye H.

    1987-01-01

    Provides in-depth content analysis of six 1985-86 prime-time television shows which featured single professional women sharing the lead with a male partner in a working relationship. Concludes that these programs show a less stereotypical portrayal of working women than in the past and demonstrate a serious attempt to present the problems of…

  15. Nanostructure Formation by controlled dewetting on patterned substrates: A combined theoretical, modeling and experimental study

    PubMed Central

    Lu, Liang-Xing; Wang, Ying-Min; Srinivasan, Bharathi Madurai; Asbahi, Mohamed; Yang, Joel K. W.; Zhang, Yong-Wei

    2016-01-01

    We perform systematic two-dimensional energetic analysis to study the stability of various nanostructures formed by dewetting solid films deposited on patterned substrates. Our analytical results show that by controlling system parameters such as the substrate surface pattern, film thickness and wetting angle, a variety of equilibrium nanostructures can be obtained. Phase diagrams are presented to show the complex relations between these system parameters and various nanostructure morphologies. We further carry out both phase field simulations and dewetting experiments to validate the analytically derived phase diagrams. Good agreements between the results from our energetic analyses and those from our phase field simulations and experiments verify our analysis. Hence, the phase diagrams presented here provide guidelines for using solid-state dewetting as a tool to achieve various nanostructures. PMID:27580943

  16. Ocean heat budget analysis on sea surface temperature anomaly in western Indian Ocean during strong-weak Asian summer monsoon

    NASA Astrophysics Data System (ADS)

    Fathrio, Ibnu; Manda, Atsuyoshi; Iizuka, Satoshi; Kodama, Yasu-Masa; Ishida, Sachinobu

    2018-05-01

    This study presents ocean heat budget analysis on seas surface temperature (SST) anomalies during strong-weak Asian summer monsoon (southwest monsoon). As discussed by previous studies, there was close relationship between variations of Asian summer monsoon and SST anomaly in western Indian Ocean. In this study we utilized ocean heat budget analysis to elucidate the dominant mechanism that is responsible for generating SST anomaly during weak-strong boreal summer monsoon. Our results showed ocean advection plays more important role to initate SST anomaly than the atmospheric prcess (surface heat flux). Scatterplot analysis showed that vertical advection initiated SST anomaly in western Arabian Sea and southwestern Indian Ocean, while zonal advection initiated SST anomaly in western equatorial Indian Ocean.

  17. [Morphometric analysis of lymphocyte nuclei in chronic lymphocytic leukemia].

    PubMed

    Ostapenko, V A; Kruchinskiĭ, N G; Smirnova, L A; Cherednik, A B; Nesterov, V N; Tepliakov, A I

    1994-01-01

    This work is dedicated to the study of use of quantitative analysis of cell nucleus structure for the analysis of peripheral blood lymphocytes in patients with chronic lymphocytic leukaemia. The structure of lymphocytic nuclei of healthy donors was evaluated by means of staining by toluidine blue purified cell suspensions smears. The preparations were analysed on the television measuring system "omnicon" with measurements of the following parameters: square of the nucleus, euchromatin, heterochromatin, and the ratio of heterochromatin and euchromatin squares. Actuarial analysis and nuclei classification of the previously mentioned parameters showed, that in peripheral blood of patients with chronic lymphocytic leukemia a large amount of atypical lymphocytes is present with reduced nucleus sizes. Atypical cells retain the ratio of structural components of chromatine, characteristic to normal cells, which show their low proliferative activity.

  18. Verbal repetitions and echolalia in Alzheimer's discourse.

    PubMed

    Da Cruz, Fernanda Miranda

    2010-11-01

    This article reports on an investigation of echolalic repetition in Alzheimer's disease (AD). A qualitative analysis of data from spontaneous conversations with MHI, a woman with AD, is presented. The data come from the DALI Corpus, a corpus of spontaneous conversations involving subjects with AD. This study argues that echolalic effects can be explained through an analysis of their formal linguistic aspects, such as intonational-prosodic and enunciative-syntactic features. The analysis shows that the description of echolalic repetitions in these terms can help find parameters for the description of the linguistic and communicative characteristics of AD. This analysis even shows how a previous speech turn serves as a base for the elaboration of the next turn by the participant with AD. It also contributes to the understanding of echolalic productions in AD.

  19. Influencing clinicians and healthcare managers: can ROC be more persuasive?

    NASA Astrophysics Data System (ADS)

    Taylor-Phillips, S.; Wallis, M. G.; Duncan, A.; Gale, A. G.

    2010-02-01

    Receiver Operating Characteristic analysis provides a reliable and cost effective performance measurement tool, without using full clinical trials. However, when ROC analysis shows that performance is statistically superior in one condition than another it is difficult to relate this result to effects in practice, or even to determine whether it is clinically significant. In this paper we present two concurrent analyses: using ROC methods alongside single threshold recall rate data, and suggest that reporting both provides complimentary data. Four mammographers read 160 difficult cases (41% malignant) twice, with and without prior mammograms. Lesion location and probability of malignancy was reported for each case and analyzed using JAFROC. Concurrently each participant chose recall or return to screen for each case. JAFROC analysis showed that the presence of prior mammograms improved performance (p<.05). Single threshold data showed a trend towards a 26% increase in the number of false positive recalls without prior mammograms (p=.056). If this trend were present throughout the NHS Breast Screening Programme then discarding prior mammograms would correspond to an increase in recall rate from 4.6% to 5.3%, and 12,414 extra women recalled annually for assessment. Whilst ROC methods account for all possible thresholds of recall and have higher power, providing a single threshold example of false positive, false negative, and recall rates when reporting results could be more influential for clinicians. This paper discusses whether this is a useful additional method of presenting data, or whether it is misleading and inaccurate.

  20. Novel insights into the composition, variation, organization, and expression of the low-molecular-weight glutenin subunit gene family in common wheat

    PubMed Central

    Zhang, Xiaofei; Liu, Dongcheng; Zhang, Jianghua; Jiang, Wei; Luo, Guangbin; Yang, Wenlong; Sun, Jiazhu; Tong, Yiping; Cui, Dangqun; Zhang, Aimin

    2013-01-01

    Low-molecular-weight glutenin subunits (LMW-GS), encoded by a complex multigene family, play an important role in the processing quality of wheat flour. Although members of this gene family have been identified in several wheat varieties, the allelic variation and composition of LMW-GS genes in common wheat are not well understood. In the present study, using the LMW-GS gene molecular marker system and the full-length gene cloning method, a comprehensive molecular analysis of LMW-GS genes was conducted in a representative population, the micro-core collections (MCC) of Chinese wheat germplasm. Generally, >15 LMW-GS genes were identified from individual MCC accessions, of which 4–6 were located at the Glu-A3 locus, 3–5 at the Glu-B3 locus, and eight at the Glu-D3 locus. LMW-GS genes at the Glu-A3 locus showed the highest allelic diversity, followed by the Glu-B3 genes, while the Glu-D3 genes were extremely conserved among MCC accessions. Expression and sequence analysis showed that 9–13 active LMW-GS genes were present in each accession. Sequence identity analysis showed that all i-type genes present at the Glu-A3 locus formed a single group, the s-type genes located at Glu-B3 and Glu-D3 loci comprised a unique group, while high-diversity m-type genes were classified into four groups and detected in all Glu-3 loci. These results contribute to the functional analysis of LMW-GS genes and facilitate improvement of bread-making quality by wheat molecular breeding programmes. PMID:23536608

  1. Steroid-antivirals treatment versus steroids alone for the treatment of Bell’s palsy: a meta-analysis

    PubMed Central

    Dong, Yabing; Zhu, Yong; Ma, Chuan; Zhao, Huaqiang

    2015-01-01

    Background: To illustrate whether the steroid-antivirals treatment could acquire a better recovery in patients with Bell’s palsy than the steroids alone treatment. Materials and methods: We conducted an exhaustive search over Pub med/Medline, Ovid, Elsevier search engines and the Cochrane library thereby collecting the randomized controlled trials in the treatment of patients with Bell’s palsy with steroid-antivirals and steroids. The qualities of relevant articles were assessed by GRADE, which was used to present the overall quality of evidence as recommended by the Cochrane Handbook for Systematic Reviews of Interventions. Results: Two investigators evaluated these papers independently, and resolved the disagreements by discussion. At last 8 eligible papers (1816 patients included: 896 treated with steroid-antivirals and 920 treated with steroids alone) match the criteria. Owing to the result (chi2 = 12.57, P = 0.08, I2 = 44%) presented by the formal test for heterogeneity, the fixed effect meta-analysis model was chosen. The facial muscle recovery between the steroids-antivirals group and the steroids alone group show significant differences (OR = 1.52, 95% CI: 1.20-1.94), while the statistical outcome of adverse effect shows no statistical significance (OR = 1.28, 95% CI: 0.71-2.31). Conclusions: The present meta-analysis indicates that the steroid-antivirals treatment could improve the recovery rate in patients with Bell’s palsy when comparing with the steroid alone treatment. Clinical significance: This meta-analysis showed that the steroid-antivirals treatment achieved the better outcomes in patients with Bell’s palsy. Clinicians should consider that steroid-antivirals therapy is an alternative choice for the patients with Bell’s palsy. PMID:25785012

  2. Production of biosolid fuels from municipal sewage sludge: Technical and economic optimisation.

    PubMed

    Wzorek, Małgorzata; Tańczuk, Mariusz

    2015-08-01

    The article presents the technical and economic analysis of the production of fuels from municipal sewage sludge. The analysis involved the production of two types of fuel compositions: sewage sludge with sawdust (PBT fuel) and sewage sludge with meat and bone meal (PBM fuel). The technology of the production line of these sewage fuels was proposed and analysed. The main objective of the study is to find the optimal production capacity. The optimisation analysis was performed for the adopted technical and economic parameters under Polish conditions. The objective function was set as a maximum of the net present value index and the optimisation procedure was carried out for the fuel production line input capacity from 0.5 to 3 t h(-1), using the search step 0.5 t h(-1). On the basis of technical and economic assumptions, economic efficiency indexes of the investment were determined for the case of optimal line productivity. The results of the optimisation analysis show that under appropriate conditions, such as prices of components and prices of produced fuels, the production of fuels from sewage sludge can be profitable. In the case of PBT fuel, calculated economic indexes show the best profitability for the capacity of a plant over 1.5 t h(-1) output, while production of PBM fuel is beneficial for a plant with the maximum of searched capacities: 3.0 t h(-1). Sensitivity analyses carried out during the investigation show that influence of both technical and economic assessments on the location of maximum of objective function (net present value) is significant. © The Author(s) 2015.

  3. Converting partially-stocked aspen stands to fully-stocked stands in the Lake States: an economic analysis.

    Treesearch

    Jeffrey T. Olson; Allen L. Lundgren

    1978-01-01

    The 1968 Wisconsin Forest Survey showed large areas of aspen type that are not considered fully stocked. The economic feasibility of converting partially-stocked stands to full stocking is examined, and a rule presented for determining when a partially-stocked stand should be harvested to maximize its present value.

  4. Wireless Laptops in English Classrooms: A SWOT Analysis from Singapore

    ERIC Educational Resources Information Center

    Towndrow, Phillip A.; Vaish, Viniti

    2009-01-01

    This paper presents illustrative findings from a one-year pilot study undertaken in the English department of a high school in Singapore that was in the first year of implementing a one-to-one wireless laptop programme. The findings show that learning was often constrained by lecture-style presentations and overt test preparation. Despite…

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Ch.; Gao, X. W.; Sladek, J.

    This paper reports our recent research works on crack analysis in continuously non-homogeneous and linear elastic functionally graded materials. A meshless boundary element method is developed for this purpose. Numerical examples are presented and discussed to demonstrate the efficiency and the accuracy of the present numerical method, and to show the effects of the material gradation on the crack-opening-displacements and the stress intensity factors.

  6. Engineering Analysis and Economic Evaluation of the Synthesis of Composite CuO/ZnO/ZrO2 Nanocatalyst

    NASA Astrophysics Data System (ADS)

    Nandiyanto, A. B. D.; Hayati, W. R.; Aziz, T. A.; Ragadhita, R.; Abdullah, A. G.; Widiaty, I.

    2018-02-01

    The purpose of this study was to evaluate the synthesis process of composite CuO/ZnO/ZrO2 (CZZ) nanocatalyst. The CZZ nanocatalyst is used as a catalyst in the hydrogenation reaction, which is used to convert harmful CO2 gas into liquid fuels such as methanol. In this study, CZZ produced using the sol-gel autocombustion method was selected as a model of the production procedure. The evaluation was conducted into two factors: engineering and economic analysis. Engineering analysis was analyzed based on the available apparatuses and raw materials in online web. Then, these data were used and compared with the mass balance approximation. The economic analysis was done using several economic parameters, including such as gross margin, internal rate return, payback period, cumulative net value, break even point (BEP), profitability index on sales to investment. Engineering analysis showed the present method can be applied using available apparatuses and raw materials in market. Economic analysis result confirmed that the present project is profitable. The analysis concluded that the present project for the production of CZZ nanocatalyst is prospective in small scale industry and profitable (by positive values in all economic parameters).

  7. Incidence Rate of Canonical vs. Derived Medical Terminology in Natural Language.

    PubMed

    Topac, Vasile; Jurcau, Daniel-Alexandru; Stoicu-Tivadar, Vasile

    2015-01-01

    Medical terminology appears in the natural language in multiple forms: canonical, derived or inflected form. This research presents an analysis of the form in which medical terminology appears in Romanian and English language. The sources of medical language used for the study are web pages presenting medical information for patients and other lay users. The results show that, in English, medical terminology tends to appear more in canonical form while, in the case of Romanian, it is the opposite. This paper also presents the service that was created to perform this analysis. This tool is available for the general public, and it is designed to be easily extensible, allowing the addition of other languages.

  8. Assessment of Uncertainties Related to Seismic Hazard Using Fuzzy Analysis

    NASA Astrophysics Data System (ADS)

    Jorjiashvili, N.; Yokoi, T.; Javakhishvili, Z.

    2013-05-01

    Seismic hazard analysis in last few decades has been become very important issue. Recently, new technologies and available data have been improved that helped many scientists to understand where and why earthquakes happen, physics of earthquakes, etc. They have begun to understand the role of uncertainty in Seismic hazard analysis. However, there is still significant problem how to handle existing uncertainty. The same lack of information causes difficulties to quantify uncertainty accurately. Usually attenuation curves are obtained in statistical way: regression analysis. Statistical and probabilistic analysis show overlapped results for the site coefficients. This overlapping takes place not only at the border between two neighboring classes, but also among more than three classes. Although the analysis starts from classifying sites using the geological terms, these site coefficients are not classified at all. In the present study, this problem is solved using Fuzzy set theory. Using membership functions the ambiguities at the border between neighboring classes can be avoided. Fuzzy set theory is performed for southern California by conventional way. In this study standard deviations that show variations between each site class obtained by Fuzzy set theory and classical way are compared. Results on this analysis show that when we have insufficient data for hazard assessment site classification based on Fuzzy set theory shows values of standard deviations less than obtained by classical way which is direct proof of less uncertainty.

  9. Analysis of cardiac signals using spatial filling index and time-frequency domain

    PubMed Central

    Faust, Oliver; Acharya U, Rajendra; Krishnan, SM; Min, Lim Choo

    2004-01-01

    Background Analysis of heart rate variation (HRV) has become a popular noninvasive tool for assessing the activities of the autonomic nervous system (ANS). HRV analysis is based on the concept that fast fluctuations may specifically reflect changes of sympathetic and vagal activity. It shows that the structure generating the signal is not simply linear, but also involves nonlinear contributions. These signals are essentially non-stationary; may contain indicators of current disease, or even warnings about impending diseases. The indicators may be present at all times or may occur at random in the time scale. However, to study and pinpoint abnormalities in voluminous data collected over several hours is strenuous and time consuming. Methods This paper presents the spatial filling index and time-frequency analysis of heart rate variability signal for disease identification. Renyi's entropy is evaluated for the signal in the Wigner-Ville and Continuous Wavelet Transformation (CWT) domain. Results This Renyi's entropy gives lower 'p' value for scalogram than Wigner-Ville distribution and also, the contours of scalogram visually show the features of the diseases. And in the time-frequency analysis, the Renyi's entropy gives better result for scalogram than the Wigner-Ville distribution. Conclusion Spatial filling index and Renyi's entropy has distinct regions for various diseases with an accuracy of more than 95%. PMID:15361254

  10. Numerical simulation of deformation and figure quality of precise mirror

    NASA Astrophysics Data System (ADS)

    Vit, Tomáš; Melich, Radek; Sandri, Paolo

    2015-01-01

    The presented paper shows results and a comparison of FEM numerical simulations and optical tests of the assembly of a precise Zerodur mirror with a mounting structure for space applications. It also shows how the curing of adhesive film can impact the optical surface, especially as regards deformations. Finally, the paper shows the results of the figure quality analysis, which are based on data from FEM simulation of optical surface deformations.

  11. Imaging discrepancies between magnetic resonance imaging and brain perfusion single-photon emission computed tomography in the diagnosis of Alzheimer's disease, and verification with amyloid positron emission tomography.

    PubMed

    Yokoyama, Shunichi; Kajiya, Yoriko; Yoshinaga, Takuma; Tani, Atsushi; Hirano, Hirofumi

    2014-06-01

    In the diagnosis of Alzheimer's disease (AD), discrepancies are often observed between magnetic resonance imaging (MRI) and brain perfusion single-photon emission computed tomography (SPECT) findings. MRI, brain perfusion SPECT, and amyloid positron emission tomography (PET) findings were compared in patients with mild cognitive impairment or early AD to clarify the discrepancies between imaging modalities. Several imaging markers were investigated, including the cortical average standardized uptake value ratio on amyloid PET, the Z-score of a voxel-based specific regional analysis system for AD on MRI, periventricular hyperintensity grade, deep white matter hyperintense signal grade, number of microbleeds, and three indicators of the easy Z-score imaging system for a specific SPECT volume-of-interest analysis. Based on the results of the regional analysis and the three indicators, we classified patients into four groups and then compared the results of amyloid PET, periventricular hyperintensity grade, deep white matter hyperintense signal grade, and the numbers of microbleeds among the groups. The amyloid deposition was the highest in the group that presented typical AD findings on both the regional analysis and the three indicators. The two groups that showed an imaging discrepancy between the regional analysis and the three indicators demonstrated intermediate amyloid deposition findings compared with the typical and atypical groups. The patients who showed hippocampal atrophy on the regional analysis and atypical AD findings using the three indicators were approximately 60% amyloid-negative. The mean periventricular hyperintensity grade was highest in the typical group. Patients showing discrepancies between MRI and SPECT demonstrated intermediate amyloid deposition findings compared with patients who showed typical or atypical findings. Strong white matter signal abnormalities on MRI in patients who presented typical AD findings provided further evidence for the involvement of vascular factors in AD. © 2014 The Authors. Psychogeriatrics © 2014 Japanese Psychogeriatric Society.

  12. Analysis of the Underlying Cognitive Activity in the Resolution of a Task on Derivability of the Absolute-Value Function: Two Theoretical Perspectives

    ERIC Educational Resources Information Center

    Pino-Fan, Luis R.; Guzmán, Ismenia; Font, Vicenç; Duval, Raymond

    2017-01-01

    This paper presents a study of networking of theories between the theory of registers of semiotic representation (TRSR) and the onto-semiotic approach of mathematical cognition and instruction (OSA). The results obtained show complementarities between these two theoretical perspectives, which might allow more detailed analysis of the students'…

  13. Studies of the Effect of Formative Assessment on Student Achievement: So Much More Is Needed

    ERIC Educational Resources Information Center

    McMillan, James H.; Venable, Jessica C.; Varier, Divya

    2013-01-01

    Kingston and Nash (2011) recently presented a meta-analysis of studies showing that the effect of formative assessment on K-12 student achievement may not be as robust as widely believed. This investigation analyzes the methodology used in the Kingston and Nash meta-analysis and provides further analyses of the studies included in the study. These…

  14. Recent statistical methods for orientation data

    NASA Technical Reports Server (NTRS)

    Batschelet, E.

    1972-01-01

    The application of statistical methods for determining the areas of animal orientation and navigation are discussed. The method employed is limited to the two-dimensional case. Various tests for determining the validity of the statistical analysis are presented. Mathematical models are included to support the theoretical considerations and tables of data are developed to show the value of information obtained by statistical analysis.

  15. Nonlinear Analysis of Surface EMG Time Series of Back Muscles

    NASA Astrophysics Data System (ADS)

    Dolton, Donald C.; Zurcher, Ulrich; Kaufman, Miron; Sung, Paul

    2004-10-01

    A nonlinear analysis of surface electromyography time series of subjects with and without low back pain is presented. The mean-square displacement and entropy shows anomalous diffusive behavior on intermediate time range 10 ms < t < 1 s. This behavior implies the presence of correlations in the signal. We discuss the shape of the power spectrum of the signal.

  16. Identification and molecular analysis of infectious bursal disease in broiler farms in the Kurdistan Regional Government of Iraq.

    PubMed

    Amin, Oumed Gerjis M; Jackwood, Daral J

    2014-10-01

    The present study was undertaken to characterize field isolates of infectious bursal disease virus (IBDV). The identification was done using reverse transcription-polymerase chain reaction (RT-PCR) and partial sequencing of the VP2 gene. Pooled bursal samples were collected from commercial broiler farms located in the Kurdistan Regional Government (KRG) of Iraq. The genetic material of the IBDV was detected in 10 out of 29 field samples. Sequences of the hypervariable VP2 region were determined for 10 of these viruses. Molecular analysis of the VP2 gene of five IBDVs showed amino acid sequences consistent with the very virulent (vv) IBDV. Two samples were identified as classic vaccine viruses, and three samples were classic vaccine viruses that appear to have mutated during replication in the field. Phylogenetic analysis showed that all five field IBDV strains of the present study were closely related to each other. On the basis of nucleotide sequencing and phylogenetic analysis, it is very likely that IBD-causing viruses in this part of Iraq are of the very virulent type. These IBDVs appear to be evolving relative to their type strains.

  17. Proceedings of the Society of Photo-Optical Instrumentation Engineers, Optical Components: Manufacture & Evaluation, Volume 171

    DTIC Science & Technology

    1979-01-22

    window locations at which interferometric measurements are gathered while the window is in motion. Figure 3 is an optical schematic and Figure 4 shows...imposed in system opera- tion although they have not been subjected to the interferometric analysis as presented here. Evaluation of Mirror #2 As...aberrations present. Introduction We present a technique for evaluating optical aberrations from interferometric data; a measured wavefront is

  18. Orion Launch Abort Vehicle Separation Analysis Using OVERFLOW

    NASA Technical Reports Server (NTRS)

    Booth, Tom

    2010-01-01

    This slide presentation reviews the use of OVERFLOW, a flow solver, to analyze the effect of separation for a launch abort vehicle (i.e., Orion capsule) if required. Included in the presentation are views of the geometry, and the Overset grids, listing of the assumptions, the general run strategy, inputs into the Overflow solver, the required computational resources, the results of the convergence study. Charts and graphics are presented to show the results.

  19. Incites Analysis of DOE National Laboratories Data for: 1990-2015

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Milligan, Shelby

    2017-07-24

    This presentation analyzes the patterns of DOE, peer publications. The data received shows which labs are leading in total peer publications and which labs are leading in peer publications under each subject.

  20. Earth Observatory Satellite system definition study. Report 1: Orbit/launch vehicle trade-off studies and recommendations

    NASA Technical Reports Server (NTRS)

    1974-01-01

    A summary of the constraints and requirements on the Earth Observatory Satellite (EOS-A) orbit and launch vehicle analysis is presented. The propulsion system (hydrazine) and the launch vehicle (Delta 2910) selected for EOS-A are examined. The rationale for the selection of the recommended orbital altitude of 418 nautical miles is explained. The original analysis was based on the EOS-A mission with the Thematic Mapper and the High Resolution Pointable Imager. The impact of the revised mission model is analyzed to show how the new mission model affects the previously defined propulsion system, launch vehicle, and orbit. A table is provided to show all aspects of the EOS multiple mission concepts. The subjects considered include the following: (1) mission orbit analysis, (2) spacecraft parametric performance analysis, (3) launch system performance analysis, and (4) orbits/launch vehicle selection.

  1. Multitemporal analysis of forest fragmentation in Hindu Kush Himalaya-a case study from Khangchendzonga Biosphere Reserve, Sikkim, India.

    PubMed

    Sharma, Mohit; Areendran, G; Raj, Krishna; Sharma, Ankita; Joshi, P K

    2016-10-01

    Forests in the mountains are a treasure trove; harbour a large biodiversity; and provide fodder, firewood, timber and non-timber forest products; all of these are essential for human survival in the highest mountains on earth. The present paper attempts a spatiotemporal assessment of forest fragmentation and changes in land use land cover (LULC) pattern using multitemporal satellite data over a time span of around a decade (2000-2009), within the third highest protected area (PA) in the world. The fragmentation analysis using Landscape Fragmentation Tool (LFT) depicts a decrease in large core, edge and patches areas by 5.93, 3.64 and 0.66 %, respectively, while an increase in non-forest and perforated areas by 6.59 and 4.01 %, respectively. The land cover dynamics shows a decrease in open forest, alpine scrub, alpine meadows, snow and hill shadow areas by 2.81, 0.39, 8.18, 3.46 and 0.60 %, respectively, and there is an increase in dense forest and glacier area by 4.79 and 10.65 %, respectively. The change analysis shows a major transformation in areas from open forest to dense forest and from alpine meadows to alpine scrub. In order to quantify changes induced by forest fragmentation and to characterize composition and configuration of LULC mosaics, fragmentation indices were computed using Fragstats at class level, showing the signs of accelerated fragmentation. The outcome of the analysis revealed the effectiveness of geospatial tools coupled with landscape ecology in characterization and quantification of forest fragmentation and land cover changes. The present study provides a baseline database for sustainable conservation planning that will benefit the subsistence livelihoods in the region. Recommendations made based on the present analysis will help to recover forest and halt the pessimistic effects of fragmentation and land cover changes on biodiversity and ecosystem services in the region.

  2. Compartmentalized Histoplasma capsulatum Infection of the Central Nervous System

    PubMed Central

    Eid, Albert J.; Leever, John D.; Husmann, Kathrin

    2015-01-01

    Background. Histoplasmosis is a common fungal infection in the southeastern, mid-Atlantic, and central states; however, its presentation can be atypical. Case Presentation. We report a case of Histoplasma capsulatum infection presenting as slowly progressive weakness in the lower extremities, followed by the development of numbness below the midthoracic area, urinary incontinence, and slurred speech. Brain MRI showed leptomeningeal enhancement, predominantly linear, involving the basal cisterns, the brainstem, and spinal cord. Cerebrospinal fluid analysis showed lymphocytic pleocytosis. Discussion. CNS histoplasmosis is usually seen in patients with disseminated histoplasmosis. Isolated CNS histoplasmosis is rarely seen, especially in immunocompetent patients. Conclusions. Histoplasmosis should be considered in the differential diagnosis of patients experiencing slowly progressive neurological deficit. PMID:26199770

  3. In-shoe plantar pressure measurement and analysis system based on fabric pressure sensing array.

    PubMed

    Shu, Lin; Hua, Tao; Wang, Yangyong; Qiao Li, Qiao; Feng, David Dagan; Tao, Xiaoming

    2010-05-01

    Spatial and temporal plantar pressure distributions are important and useful measures in footwear evaluation, athletic training, clinical gait analysis, and pathology foot diagnosis. However, present plantar pressure measurement and analysis systems are more or less uncomfortable to wear and expensive. This paper presents an in-shoe plantar pressure measurement and analysis system based on a textile fabric sensor array, which is soft, light, and has a high-pressure sensitivity and a long service life. The sensors are connected with a soft polymeric board through conductive yarns and integrated into an insole. A stable data acquisition system interfaces with the insole, wirelessly transmits the acquired data to remote receiver through Bluetooth path. Three configuration modes are incorporated to gain connection with desktop, laptop, or smart phone, which can be configured to comfortably work in research laboratories, clinics, sport ground, and other outdoor environments. A real-time display and analysis software is presented to calculate parameters such as mean pressure, peak pressure, center of pressure (COP), and shift speed of COP. Experimental results show that this system has stable performance in both static and dynamic measurements.

  4. An economic analysis of alternative paving materials

    NASA Astrophysics Data System (ADS)

    Mustain, J. L.

    1982-12-01

    The purpose of this paper is to present a means for economic analysis of alternative equivalent pavement designs, considering such factors as initial construction cost, annual maintenance cost, salvage value and the various intangibles which occur during the analysis period. Having established a means of economic comparison, it is then the intent of this paper to show that Portland Cement Concrete has been and is a viable pavement alternative and ought to receive due consideration in the military construction program.

  5. A theoretical analysis of the free vibrations of ring- and/or stringer-stiffened elliptical cylinders with arbitrary end conditions. Volume 1: Analytical derivation and applications

    NASA Technical Reports Server (NTRS)

    Boyd, D. E.; Rao, C. K. P.

    1973-01-01

    The derivation and application of a Rayleigh-Ritz modal vibration analysis are presented for ring and/or stringer stiffened noncircular cylindrical shells with arbitrary end conditions. Comparisons with previous results from experimental and analytical studies showed this method of analysis to be accurate for a variety of end conditions. Results indicate a greater effect of rings on natural frequencies than of stringers.

  6. The Crew Earth Observations Experiment: Earth System Science from the ISS

    NASA Technical Reports Server (NTRS)

    Stefanov, William L.; Evans, Cynthia A.; Robinson, Julie A.; Wilkinson, M. Justin

    2007-01-01

    This viewgraph presentation reviews the use of Astronaut Photography (AP) as taken from the International Space Station (ISS) in Earth System Science (ESS). Included are slides showing basic remote sensing theory, data characteristics of astronaut photography, astronaut training and operations, crew Earth observations group, targeting sites and acquisition, cataloging and database, analysis and applications for ESS, image analysis of particular interest urban areas, megafans, deltas, coral reefs. There are examples of the photographs and the analysis.

  7. Enhancing Safety of Artificially Ventilated Patients Using Ambient Process Analysis.

    PubMed

    Lins, Christian; Gerka, Alexander; Lüpkes, Christian; Röhrig, Rainer; Hein, Andreas

    2018-01-01

    In this paper, we present an approach for enhancing the safety of artificially ventilated patients using ambient process analysis. We propose to use an analysis system consisting of low-cost ambient sensors such as power sensor, RGB-D sensor, passage detector, and matrix infrared temperature sensor to reduce risks for artificially ventilated patients in both home and clinical environments. We describe the system concept and our implementation and show how the system can contribute to patient safety.

  8. Quasi-one-dimensional compressible flow across face seals and narrow slots. 1: Analysis

    NASA Technical Reports Server (NTRS)

    Zuk, J.; Ludwig, L. P.; Johnson, R. L.

    1972-01-01

    An analysis is presented for compressible fluid flow across shaft face seals and narrow slots. The analysis includes fluid inertia, viscous friction, and entrance losses. Subsonic and choked flow conditions can be predicted and analyzed. The model is valid for both laminar and turbulent flows. Results agree with experiment and with solutions which are more limited in applicability. Results show that a parallel film can have a positive film stiffness under choked flow conditions.

  9. Multi-level Discourse Analysis in a Physics Teaching Methods Course from the Psychological Perspective of Activity Theory

    NASA Astrophysics Data System (ADS)

    Vieira, Rodrigo Drumond; Kelly, Gregory J.

    2014-11-01

    In this paper, we present and apply a multi-level method for discourse analysis in science classrooms. This method is based on the structure of human activity (activity, actions, and operations) and it was applied to study a pre-service physics teacher methods course. We argue that such an approach, based on a cultural psychological perspective, affords opportunities for analysts to perform a theoretically based detailed analysis of discourse events. Along with the presentation of analysis, we show and discuss how the articulation of different levels offers interpretative criteria for analyzing instructional conversations. We synthesize the results into a model for a teacher's practice and discuss the implications and possibilities of this approach for the field of discourse analysis in science classrooms. Finally, we reflect on how the development of teachers' understanding of their activity structures can contribute to forms of progressive discourse of science education.

  10. Proceedings of the 5th Symposium on applied surface analysis

    NASA Astrophysics Data System (ADS)

    Grant, J. T.

    1984-04-01

    The 5th Symposium on Applied Surface Analysis was held at the University of Dayton, 8-10 June 1983. This Symposium was held to meet a need, namely to show the transition between basic surface science research and applications of this research to areas of Department of Defense interest. Areas receiving special attention at this Symposium were chemical bonding and reactions at metal-semiconductors interfaces, surface analysis and the tribological processes of ion implanted materials, microbeam analysis and laser ionization of sputtered neutrals. Other topics discussed included adsorption, adhesion, corrosion, wear and thin films. Approximately 110 scientists active in the field of surface analysis participated in the Symposium. Four scientists presented invited papers at the Symposium. There were 29 contributed presentations. The proceedings of the Symposium are being published in a special issue of the journal, Applications of Surface Science, by North-Holland Publishing Company.

  11. Sustained modelling ability of artificial neural networks in the analysis of two pharmaceuticals (dextropropoxyphene and dipyrone) present in unequal concentrations.

    PubMed

    Cámara, María S; Ferroni, Félix M; De Zan, Mercedes; Goicoechea, Héctor C

    2003-07-01

    An improvement is presented on the simultaneous determination of two active ingredients present in unequal concentrations in injections. The analysis was carried out with spectrophotometric data and non-linear multivariate calibration methods, in particular artificial neural networks (ANNs). The presence of non-linearities caused by the major analyte concentrations which deviate from Beer's law was confirmed by plotting actual vs. predicted concentrations, and observing curvatures in the residuals for the estimated concentrations with linear methods. Mixtures of dextropropoxyphene and dipyrone have been analysed by using linear and non-linear partial least-squares (PLS and NPLSs) and ANNs. Notwithstanding the high degree of spectral overlap and the occurrence of non-linearities, rapid and simultaneous analysis has been achieved, with reasonably good accuracy and precision. A commercial sample was analysed by using the present methodology, and the obtained results show reasonably good agreement with those obtained by using high-performance liquid chromatography (HPLC) and a UV-spectrophotometric comparative methods.

  12. Convergence acceleration of the Proteus computer code with multigrid methods

    NASA Technical Reports Server (NTRS)

    Demuren, A. O.; Ibraheem, S. O.

    1995-01-01

    This report presents the results of a study to implement convergence acceleration techniques based on the multigrid concept in the two-dimensional and three-dimensional versions of the Proteus computer code. The first section presents a review of the relevant literature on the implementation of the multigrid methods in computer codes for compressible flow analysis. The next two sections present detailed stability analysis of numerical schemes for solving the Euler and Navier-Stokes equations, based on conventional von Neumann analysis and the bi-grid analysis, respectively. The next section presents details of the computational method used in the Proteus computer code. Finally, the multigrid implementation and applications to several two-dimensional and three-dimensional test problems are presented. The results of the present study show that the multigrid method always leads to a reduction in the number of iterations (or time steps) required for convergence. However, there is an overhead associated with the use of multigrid acceleration. The overhead is higher in 2-D problems than in 3-D problems, thus overall multigrid savings in CPU time are in general better in the latter. Savings of about 40-50 percent are typical in 3-D problems, but they are about 20-30 percent in large 2-D problems. The present multigrid method is applicable to steady-state problems and is therefore ineffective in problems with inherently unstable solutions.

  13. Recent amplification and impact of MITEs on the genome of grapevine (Vitis vinifera L.)

    PubMed Central

    Benjak, Andrej; Boué, Stéphanie; Forneck, Astrid

    2009-01-01

    Miniature inverted-repeat transposable elements (MITEs) are a particular type of defective class II transposons present in genomes as highly homogeneous populations of small elements. Their high copy number and close association to genes make their potential impact on gene evolution particularly relevant. Here, we present a detailed analysis of the MITE families directly related to grapevine “cut-and-paste” transposons. Our results show that grapevine MITEs have transduplicated and amplified genomic sequences, including gene sequences and fragments of other mobile elements. Our results also show that although some of the MITE families were already present in the ancestor of the European and American Vitis wild species, they have been amplified and have been actively transposing accompanying grapevine domestication and breeding. We show that MITEs are abundant in grapevine and some of them are frequently inserted within the untranslated regions of grapevine genes. MITE insertions are highly polymorphic among grapevine cultivars, which frequently generate transcript variability. The data presented here show that MITEs have greatly contributed to the grapevine genetic diversity which has been used for grapevine domestication and breeding. PMID:20333179

  14. Tropospheric ozone (TOR) trend over three major inland Indian cities: Delhi, Hyderabad and Bangalore

    NASA Astrophysics Data System (ADS)

    Kulkarni, Pavan S.; Ghude, Sachin D.; Bortoli, D.

    2010-10-01

    An analysis of tropospheric column ozone using the NASA Langley TOR data during 1979-2005 has been done to investigate the trend over major Indian cities Delhi, Hyderabad and Bangalore. India was under social democratic-based policies before 1990s. Economic Liberalization began in nineties which lead to a significant growth in industrial, energy and transport sectors in major cities. Our analysis shows that there is a systematic increase in the number of months with higher tropospheric ozone values after 1990. A comparison of TOR climatology before and after 1990 over these cities shows evidence of increase in the tropospheric ozone after 1990. Trend obtained from the model shows significant change during monsoon over Delhi and during pre-monsoon and post-monsoon over Hyderabad and Bangalore. The present analysis using TOR technique demonstrates the TOR potential to detect changes in tropospheric ozone over large cities which are impacted by large anthropogenic pollution.

  15. Physicochemical characterization, fatty acid composition, and thermal analysis of Bertholletia excelsa HBK oil

    PubMed Central

    Pena Muniz, Marcos Antônio; Ferreira dos Santos, Marina Nídia; da Costa, Carlos Emmerson Ferreira; Morais, Luiz; Lamarão, Maria Louze Nobre; Ribeiro-Costa, Roseane Maria; Silva-Júnior, José Otávio Carréra

    2015-01-01

    The present study aimed at characterizing the oil extracted from Bertholletia excelsa H.B.K. almond, a native species from the Amazon region. Analytical methods used for oils and fats were employed through pharmacopoeia assays, AOCS (American Oil Chemists Society) standard methods as well as those recommended by ANVISA (National Health Surveillance Agency) such as acidity, peroxide value, saponification index, iodine value and refractive index, pH and relative density, and also thermoanalytical analyses (thermogravimetry, differential thermogravimetry and differential thermal analysis) as well as chromatographic analysis (gas chromatography). The characterization assessments of B. excelsa oil showed results indicating that the oil contains polyunsaturated fatty acids in large proportion. The termoanalytical tests indicated that B.excelsa oil showed thermal stability up to 220 °C, These results showed that the oil extracted from B. excelsa has acceptable characteristics and is of good quality. PMID:25709225

  16. Tsunami and shelf resonance on the northern Chile coast

    NASA Astrophysics Data System (ADS)

    Cortés, Pablo; Catalán, Patricio A.; Aránguiz, Rafael; Bellotti, Giorgio

    2017-09-01

    This work presents the analysis of long waves resonance in two of the main cities along the northern coast of Chile, Arica, and Iquique, where a large tsunamigenic potential remains despite recent earthquakes. By combining a modal analysis solving the equation of free surface oscillations, with the analysis of background spectra derived from in situ measurements, the spatial and temporal structures of the modes are recovered. Comparison with spectra from three tsunamis of different characteristics shows that the modes found have been excited by past events. Moreover, the two locations show different response patterns. Arica is more sensitive to the characteristics of the tsunami source, whereas Iquique shows a smaller dependency and similar response for different tsunami events. Results are further compared with other methodologies with good agreement. These findings are relevant in characterizing the tsunami hazard in the area, and the methodology can be further extended to other regions along the Chilean coast.

  17. A summary of phase analysis on Apollo 14 samples

    NASA Technical Reports Server (NTRS)

    Fredriksson, K.; Nelen, J.; Noonan, A.; Kraut, F.

    1971-01-01

    The results of an analysis of lunar samples from Apollo 14 are presented. The large number of breccias returned from the Fra Mauro formation show that impact events are an important rock forming mechanism on the moon. Larger rocks as well as micro breccias bear structural resemblance to brecciated chondrites and terrestrial impactites. Many show evidence of repetitious events of break-up and accumulation welding. The surface of the regolith has become thoroughly mixed by this process. Most components however appear locally derived from basalts rich in feldspar and Kreep components, similar to rocks such as 14310.

  18. Analysis of Malicious Traffic in Modbus/TCP Communications

    NASA Astrophysics Data System (ADS)

    Kobayashi, Tiago H.; Batista, Aguinaldo B.; Medeiros, João Paulo S.; Filho, José Macedo F.; Brito, Agostinho M.; Pires, Paulo S. Motta

    This paper presents the results of our analysis about the influence of Information Technology (IT) malicious traffic on an IP-based automation environment. We utilized a traffic generator, called MACE (Malicious trAffic Composition Environment), to inject malicious traffic in a Modbus/TCP communication system and a sniffer to capture and analyze network traffic. The realized tests show that malicious traffic represents a serious risk to critical information infrastructures. We show that this kind of traffic can increase latency of Modbus/TCP communication and that, in some cases, can put Modbus/TCP devices out of communication.

  19. Northrop F-5F shark nose development

    NASA Technical Reports Server (NTRS)

    Edwards, O. R.

    1978-01-01

    During spin susceptibility testing of the Northrop F-5F airplane, two erect spin entries were obtained from purely longitudinal control inputs at low speed. Post flight analysis of the data showed that the initial yaw departure occurred at zero sideslip, and review of wind tunnel data showed significant yawing moments present at angles of attack well above stall. Further analysis of this wind tunnel data indicated that the yawing moments were being generated by the long slender nose of the airplane. Redesign of the nose was accomplished, resulting in a nose configuration which completely alleviated the asymmetric yawing moments.

  20. Comparative analysis of taxonomic, functional, and metabolic patterns of microbiomes from 14 full-scale biogas reactors by metagenomic sequencing and radioisotopic analysis.

    PubMed

    Luo, Gang; Fotidis, Ioannis A; Angelidaki, Irini

    2016-01-01

    Biogas production is a very complex process due to the high complexity in diversity and interactions of the microorganisms mediating it, and only limited and diffuse knowledge exists about the variation of taxonomic and functional patterns of microbiomes across different biogas reactors, and their relationships with the metabolic patterns. The present study used metagenomic sequencing and radioisotopic analysis to assess the taxonomic, functional, and metabolic patterns of microbiomes from 14 full-scale biogas reactors operated under various conditions treating either sludge or manure. The results from metagenomic analysis showed that the dominant methanogenic pathway revealed by radioisotopic analysis was not always correlated with the taxonomic and functional compositions. It was found by radioisotopic experiments that the aceticlastic methanogenic pathway was dominant, while metagenomics analysis showed higher relative abundance of hydrogenotrophic methanogens. Principal coordinates analysis showed the sludge-based samples were clearly distinct from the manure-based samples for both taxonomic and functional patterns, and canonical correspondence analysis showed that the both temperature and free ammonia were crucial environmental variables shaping the taxonomic and functional patterns. The study further the overall patterns of functional genes were strongly correlated with overall patterns of taxonomic composition across different biogas reactors. The discrepancy between the metabolic patterns determined by metagenomic analysis and metabolic pathways determined by radioisotopic analysis was found. Besides, a clear correlation between taxonomic and functional patterns was demonstrated for biogas reactors, and also the environmental factors that shaping both taxonomic and functional genes patterns were identified.

  1. Analysis and design of planar waveguide elements for use in filters and sensors

    NASA Astrophysics Data System (ADS)

    Chen, Guangzhou

    In this dissertation we present both theoretical analysis and practical design considerations for planar optical waveguide devices. The analysis takes into account both transverse dimensions of the waveguides and is based on supermode theory combined with the resonance method for the determination of the propagation constants and field profiles of the supermodes. An improved accuracy has been achieved by including corrections due to the fields in the corner regions of the waveguides using perturbation theory. We analyze in detail two particular devices, an optical filter/combiner and an optical sensor. An optical wavelength filter/combiner is a common element in an integrated optical circuit. A new "bend free" filter/combiner is proposed and analyzed. The new wavelength filter consists of only straight parallel channels, which considerably simplify both the analysis and fabrication of the device. We show in detail how the operation of the device depends upon each of the design parameters. The intrinsic power loss in the proposed filter/combiner is minimized. The optical sensor is another important device and the sensitivity of measurement is an important issue in its design. Two operating mechanisms used in prior optical sensors are evanescent wave sensing or surface plasmon excitation. In this dissertation, we present a sensor with a directional coupler structure in which a measurand to be detected is interfaced with one side of the cladding. The analysis shows that it is possible to make a high resolution device by adjusting the design parameters. The dimensions and materials used in an optimized design are presented.

  2. The Neonatal Connectome During Preterm Brain Development

    PubMed Central

    van den Heuvel, Martijn P.; Kersbergen, Karina J.; de Reus, Marcel A.; Keunen, Kristin; Kahn, René S.; Groenendaal, Floris; de Vries, Linda S.; Benders, Manon J.N.L.

    2015-01-01

    The human connectome is the result of an elaborate developmental trajectory. Acquiring diffusion-weighted imaging and resting-state fMRI, we studied connectome formation during the preterm phase of macroscopic connectome genesis. In total, 27 neonates were scanned at week 30 and/or week 40 gestational age (GA). Examining the architecture of the neonatal anatomical brain network revealed a clear presence of a small-world modular organization before term birth. Analysis of neonatal functional connectivity (FC) showed the early formation of resting-state networks, suggesting that functional networks are present in the preterm brain, albeit being in an immature state. Moreover, structural and FC patterns of the neonatal brain network showed strong overlap with connectome architecture of the adult brain (85 and 81%, respectively). Analysis of brain development between week 30 and week 40 GA revealed clear developmental effects in neonatal connectome architecture, including a significant increase in white matter microstructure (P < 0.01), small-world topology (P < 0.01) and interhemispheric FC (P < 0.01). Computational analysis further showed that developmental changes involved an increase in integration capacity of the connectivity network as a whole. Taken together, we conclude that hallmark organizational structures of the human connectome are present before term birth and subject to early development. PMID:24833018

  3. Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma

    PubMed Central

    Cooke, Susanna L; Ng, Charlotte KY; Melnyk, Nataliya; Garcia, Maria J; Hardcastle, Tom; Temple, Jillian; Langdon, Simon; Huntsman, David; Brenton, James D

    2010-01-01

    Resistance to chemotherapy in ovarian cancer is poorly understood. Evolutionary models of cancer predict that, following treatment, resistance emerges either due to outgrowth of an intrinsically resistant sub-clone, or evolves in residual disease under the selective pressure of treatment. To investigate genetic evolution in high-grade serous (HGS) ovarian cancers we first analysed cell line series derived from three cases of HGS carcinoma before and after platinum resistance had developed (PEO1, PEO4 and PEO6, PEA1 and PEA2, and PEO14 and PEO23). Analysis with 24-colour fluorescence in situ hybridisation and SNP array comparative genomic hybridisation (CGH) showed mutually exclusive endoreduplication and loss of heterozygosity events in clones present at different timepoints in the same individual. This implies that platinum sensitive and resistant disease was not linearly related but shared a common ancestor at an early stage of tumour development. Array CGH analysis of six paired pre- and post-neoadjuvant treatment HGS samples from the CTCR-OV01 clinical study did not show extensive copy number differences, suggesting that one clone was strongly dominant at presentation. These data show that cisplatin resistance in HGS carcinoma develops from pre-existing minor clones but that enrichment for these clones is not apparent during short-term chemotherapy treatment. PMID:20581869

  4. Socio-Hydrology of Channel Flows in Complex River Basins: Rivers, Canals, and Distributaries in Punjab, Pakistan

    NASA Astrophysics Data System (ADS)

    Wescoat, James L.; Siddiqi, Afreen; Muhammad, Abubakr

    2018-01-01

    This paper presents a socio-hydrologic analysis of channel flows in Punjab province of the Indus River basin in Pakistan. The Indus has undergone profound transformations, from large-scale canal irrigation in the mid-nineteenth century to partition and development of the international river basin in the mid-twentieth century, systems modeling in the late-twentieth century, and new technologies for discharge measurement and data analytics in the early twenty-first century. We address these processes through a socio-hydrologic framework that couples historical geographic and analytical methods at three levels of flow in the Punjab. The first level assesses Indus River inflows analysis from its origins in 1922 to the present. The second level shows how river inflows translate into 10-daily canal command deliveries that vary widely in their conformity with canal entitlements. The third level of analysis shows how new flow measurement technologies raise questions about the performance of established methods of water scheduling (warabandi) on local distributaries. We show how near real-time measurement sheds light on the efficiency and transparency of surface water management. These local socio-hydrologic changes have implications in turn for the larger scales of canal and river inflow management in complex river basins.

  5. Economic Evaluation of the Production Magnesium Oxide Nanoparticles via Liquid-Phase Route

    NASA Astrophysics Data System (ADS)

    Nandiyanto, A. B. D.; Fariansyah, R.; Ramadhan, M. F.; Abdullah, A. G.; Widiaty, I.

    2018-02-01

    The purpose of this study was to evaluate the production of magnesium oxide (MgO) nanoparticles. The evaluation was done in two perspectives: engineering and economic evaluation. The engineering perspective concerned about the analysis of the production rate based on the available apparatuses and raw materials, completed with mass balance calculation. The economic analysis was conducted based on several economic parameters: gross profit margin (GPM), internal return rate (IRR), payback period (PBP), cumulative net present value (CNPV), break even point (BEP), and profit to investment (PI). The engineering perspective showed that the production of MgO is feasibly done in small scale industry. This is verified by the potential production using current available apparatuses and raw materials in the market. Economic analysis obtained that the present project is profitable. But, for some cases, further studies must be done to get the present production process is attractive for investor.

  6. High pressure jet flame numerical analysis of CO emissions by means of the flamelet generated manifolds technique

    NASA Astrophysics Data System (ADS)

    Donini, A.; Martin, S. M.; Bastiaans, R. J. M.; van Oijen, J. A.; de Goey, L. P. H.

    2013-10-01

    In the present paper a computational analysis of a high pressure confined premixed turbulent methane/air jet flames is presented. In this scope, chemistry is reduced by the use of the Flamelet Generated Manifold method [1] and the fluid flow is modeled in an LES and RANS context. The reaction evolution is described by the reaction progress variable, the heat loss is described by the enthalpy and the turbulence effect on the reaction is represented by the progress variable variance. The interaction between chemistry and turbulence is considered through a presumed probability density function (PDF) approach. The use of FGM as a combustion model shows that combustion features at gas turbine conditions can be satisfactorily reproduced with a reasonable computational effort. Furthermore, the present analysis indicates that the physical and chemical processes controlling carbon monoxide (CO) emissions can be captured only by means of unsteady simulations.

  7. A Numerical Analysis of the Resistance and Stiffness of the Timber and Concrete Composite Beam

    NASA Astrophysics Data System (ADS)

    Szumigała, Ewa; Szumigała, Maciej; Polus, Łukasz

    2015-03-01

    The article presents the results of a numerical analysis of the load capacity and stiffness of the composite timber and concrete beam. Timber and concrete structures are relatively new, they have not been thoroughly tested and they are rarely used because of technological constraints. One of the obstacles to using them is difficulty with finding a method which would allow successful cooperation between concrete and timber, which has been proposed by the authors of the present article. The modern idea of sustainable construction design requires the use of new more environmentally-friendly solutions. Wood as an ecological material is easily accessible, less energy-consuming, and under certain conditions more corrosion-resistant than steel. The analysis presented in the article showed that cooperation between a wooden beam and a concrete slab on profiled steel sheeting is possible. The analysed composite beam has a greater load capacity and stiffness than the wooden beam.

  8. Portfolio analysis of layered security measures.

    PubMed

    Chatterjee, Samrat; Hora, Stephen C; Rosoff, Heather

    2015-03-01

    Layered defenses are necessary for protecting the public from terrorist attacks. Designing a system of such defensive measures requires consideration of the interaction of these countermeasures. In this article, we present an analysis of a layered security system within the lower Manhattan area. It shows how portfolios of security measures can be evaluated through portfolio decision analysis. Consideration is given to the total benefits and costs of the system. Portfolio diagrams are created that help communicate alternatives among stakeholders who have differing views on the tradeoffs between security and economic activity. © 2014 Society for Risk Analysis.

  9. Hyperexcretion of homocitrulline in a Malaysian patient with lysinuric protein intolerance.

    PubMed

    Habib, Anasufiza; Md Yunus, Zabedah; Azize, Nor Azimah; Ch'ng, Gaik-Siew; Ong, Winnie Peitee; Chen, Bee-Chin; Hsu, Ho-Torng; Wong, Ke-Juin; Pitt, James; Ngu, Lock-Hock

    2013-09-01

    Lysinuric protein intolerance (LPI; MIM 222700) is an inherited aminoaciduria with an autosomal recessive mode of inheritance. Biochemically, affected patients present with increased excretion of the cationic amino acids: lysine, arginine, and ornithine. We report the first case of LPI diagnosed in Malaysia presented with excessive excretion of homocitrulline. The patient was a 4-year-old male who presented with delayed milestones, recurrent diarrhea, and severe failure to thrive. He developed hyperammonemic coma following a forced protein-rich diet. Plasma amino acid analysis showed increased glutamine, alanine, and citrulline but decreased lysine, arginine and ornithine. Urine amino acids showed a marked excretion of lysine and ornithine together with a large peak of unknown metabolite which was subsequently identified as homocitrulline by tandem mass spectrometry. Molecular analysis confirmed a previously unreported homozygous mutation at exon 1 (235 G > A, p.Gly79Arg) in the SLC7A7 gene. This report demonstrates a novel mutation in the SLC7A7 gene in this rare inborn error of diamino acid metabolism. It also highlights the importance of early and efficient treatment of infections and dehydration in these patients. The diagnosis of LPI is usually not suspected by clinical findings alone, and specific laboratory investigations and molecular analysis are important to get a definitive diagnosis.

  10. Light effects on the multicellular magnetotactic prokaryote 'Candidatus Magnetoglobus multicellularis' are cancelled by radiofrequency fields: the involvement of radical pair mechanisms.

    PubMed

    de Melo, Roger Duarte; Acosta-Avalos, Daniel

    2017-02-01

    'Candidatus Magnetoglobus multicellularis' is the most studied multicellular magnetotactic prokaryote. It presents a light-dependent photokinesis: green light decreases the translation velocity whereas red light increases it, in comparison to blue and white light. The present article shows that radio-frequency electromagnetic fields cancel the light effect on photokinesis. The frequency to cancel the light effect corresponds to the Zeeman resonance frequency (DC magnetic field of 4 Oe and radio-frequency of 11.5 MHz), indicating the involvement of a radical pair mechanism. An analysis of the orientation angle relative to the magnetic field direction shows that radio-frequency electromagnetic fields disturb the swimming orientation when the microorganisms are illuminated with red light. The analysis also shows that at low magnetic fields (1.6 Oe) the swimming orientation angles are well scattered around the magnetic field direction, showing that magnetotaxis is not efficiently in the swimming orientation to the geomagnetic field. The results do not support cryptochrome as being the responsible chromophore for the radical pair mechanism and perhaps two different chromophores are necessary to explain the radio-frequency effects.

  11. Chandra Interactive Analysis of Observations (CIAO)

    NASA Technical Reports Server (NTRS)

    Dobrzycki, Adam

    2000-01-01

    The Chandra (formerly AXAF) telescope, launched on July 23, 1999, provides X-rays data with unprecedented spatial and spectral resolution. As part of the Chandra scientific support, the Chandra X-ray Observatory Center provides a new data analysis system, CIAO ("Chandra Interactive Analysis of Observations"). We will present the main components of the system: "First Look" analysis; SHERPA: a multi-dimensional, multi-mission modeling and fitting application; Chandra Imaging and Plotting System; Detect package-source detection algorithms; and DM package generic data manipulation tools, We will set up a demonstration of the portable version of the system and show examples of Chandra Data Analysis.

  12. Oceanographic features in the lee of the windward and leeward islands: ERTS and ship data

    NASA Technical Reports Server (NTRS)

    Hanson, K. J.; Hebard, F.; Cram, R.

    1973-01-01

    Analysis of the ERTS data in portions of the eastern Caribbean are presented for October 1972 showing features which are, as yet, not explained. Ground truth data obtained in that area during November 1972 are presented. These include vertical temperature structure in the mixed layer and thermocline, and surface measurements of salinity, temperature, and chlorophyll.

  13. Improved separability criteria via some classes of measurements

    NASA Astrophysics Data System (ADS)

    Shen, Shu-Qian; Li, Ming; Li-Jost, Xianqing; Fei, Shao-Ming

    2018-05-01

    The entanglement detection via local measurements can be experimentally implemented. Based on mutually unbiased measurements and general symmetric informationally complete positive-operator-valued measures, we present separability criteria for bipartite quantum states, which, by theoretical analysis, are stronger than the related existing criteria via these measurements. Two detailed examples are supplemented to show the efficiency of the presented separability criteria.

  14. Comment on ``Steady-state properties of a totally asymmetric exclusion process with periodic structure''

    NASA Astrophysics Data System (ADS)

    Jiang, Rui; Hu, Mao-Bin; Wu, Qing-Song

    2008-07-01

    Lakatos [Phys. Rev. E 71, 011103 (2005)] have studied a totally asymmetric exclusion process that contains periodically varying movement rates. They have presented a cluster mean-field theory for the problem. We show that their cluster mean-field theory leads to redundant equations. We present a mean-field analysis in which there is no redundant equation.

  15. Working Memory Enhances Visual Perception: Evidence from Signal Detection Analysis

    ERIC Educational Resources Information Center

    Soto, David; Wriglesworth, Alice; Bahrami-Balani, Alex; Humphreys, Glyn W.

    2010-01-01

    We show that perceptual sensitivity to visual stimuli can be modulated by matches between the contents of working memory (WM) and stimuli in the visual field. Observers were presented with an object cue (to hold in WM or to merely attend) and subsequently had to identify a brief target presented within a colored shape. The cue could be…

  16. Factor Analysis of the Brazilian Version of UPPS Impulsive Behavior Scale.

    PubMed

    Sediyama, Cristina Y N; Moura, Ricardo; Garcia, Marina S; da Silva, Antonio G; Soraggi, Carolina; Neves, Fernando S; Albuquerque, Maicon R; Whiteside, Setephen P; Malloy-Diniz, Leandro F

    2017-01-01

    Objective: To examine the internal consistency and factor structure of the Brazilian adaptation of the UPPS Impulsive Behavior Scale. Methods: UPPS is a self-report scale composed by 40 items assessing four factors of impulsivity: (a) urgency, (b) lack of premeditation; (c) lack of perseverance; (d) sensation seeking. In the present study 384 participants (278 women and 106 men), who were recruited from schools, universities, leisure centers and workplaces fulfilled the UPPS scale. An exploratory factor analysis was performed by using Varimax factor rotation and Kaiser Normalization, and we also conducted two confirmatory analyses to test the independency of the UPPS components found in previous analysis. Results: Results showed a decrease in mean UPPS total scores with age and this analysis showed that the youngest participants (below 30 years) scored significantly higher than the other groups over 30 years. No difference in gender was found. Cronbach's alpha, results indicated satisfactory values for all subscales, with similar high values for the subscales and confirmatory factor analysis indexes also indicated a poor model fit. The results of two exploratory factor analysis were satisfactory. Conclusion: Our results showed that the Portuguese version has the same four-factor structure of the original and previous translations of the UPPS.

  17. Chemometric Data Analysis for Deconvolution of Overlapped Ion Mobility Profiles

    NASA Astrophysics Data System (ADS)

    Zekavat, Behrooz; Solouki, Touradj

    2012-11-01

    We present the details of a data analysis approach for deconvolution of the ion mobility (IM) overlapped or unresolved species. This approach takes advantage of the ion fragmentation variations as a function of the IM arrival time. The data analysis involves the use of an in-house developed data preprocessing platform for the conversion of the original post-IM/collision-induced dissociation mass spectrometry (post-IM/CID MS) data to a Matlab compatible format for chemometric analysis. We show that principle component analysis (PCA) can be used to examine the post-IM/CID MS profiles for the presence of mobility-overlapped species. Subsequently, using an interactive self-modeling mixture analysis technique, we show how to calculate the total IM spectrum (TIMS) and CID mass spectrum for each component of the IM overlapped mixtures. Moreover, we show that PCA and IM deconvolution techniques provide complementary results to evaluate the validity of the calculated TIMS profiles. We use two binary mixtures with overlapping IM profiles, including (1) a mixture of two non-isobaric peptides (neurotensin (RRPYIL) and a hexapeptide (WHWLQL)), and (2) an isobaric sugar isomer mixture of raffinose and maltotriose, to demonstrate the applicability of the IM deconvolution.

  18. Applications of HPLC/MS in the analysis of traditional Chinese medicines

    PubMed Central

    Li, Miao; Hou, Xiao-Fang; Zhang, Jie; Wang, Si-Cen; Fu, Qiang; He, Lang-Chong

    2012-01-01

    In China, traditional Chinese medicines (TCMs) have been used in clinical applications for thousands of years. The successful hyphenation of high-Performance liquid chromatography (HPLC) and mass spectrometry (MS) has been applied widely in TCMs and biological samples analysis. Undoubtedly, HPLC/MS technique has facilitated the understanding of the treatment mechanism of TCMs. We reviewed more than 350 published papers within the last 5 years on HPLC/MS in the analysis of TCMs. The present review focused on the applications of HPLC/MS in the component analysis, metabolites analysis, and pharmacokinetics of TCMs etc. 50% of the literature is related to the component analysis of TCMs, which show that this field is the most populär type of research. In the metabolites analysis, HPLC coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry has been demonstrated to be the powerful tool for the characterization of structural features and fragmentation behavior patterns. This paper presented a brief overview of the applications of HPLC/MS in the analysis of TCMs. HPLC/MS in the fingerprint analysis is reviewed elsewhere. PMID:29403684

  19. Association analysis between spatiotemporal variation of vegetation greenness and precipitation/temperature in the Yangtze River Basin (China).

    PubMed

    Cui, Lifang; Wang, Lunche; Singh, Ramesh P; Lai, Zhongping; Jiang, Liangliang; Yao, Rui

    2018-05-23

    The variation in vegetation greenness provides good understanding of the sustainable management and monitoring of land surface ecosystems. The present paper discusses the spatial-temporal changes in vegetation and controlling factors in the Yangtze River Basin (YRB) using Global Inventory Modeling and Mapping Studies (GIMMS) Normalized Difference Vegetation Index (NDVI) for the period 2001-2013. Theil-Sen Median trend analysis, Pearson correlation coefficients, and residual analysis have been used, which shows decreasing trend of the annual mean NDVI over the whole YRB. Spatially, the regions with significant decreasing trends were mainly located in parts of central YRB, and pronounced increasing trends were observed in parts of the eastern and western YRB. The mean NDVI during spring and summer seasons increased, while it decreased during autumn and winter seasons. The seasonal mean NDVI shows spatial heterogeneity due to the vegetation types. The correlation analysis shows a positive relation between NDVI and temperature over most of the YRB, whereas NDVI and precipitation show a negative correlation. The residual analysis shows an increase in NDVI in parts of eastern and western YRB and the decrease in NDVI in the small part of Yangtze River Delta (YRD) and the mid-western YRB due to human activities. In general, climate factors were the principal drivers of NDVI variation in YRB in recent years.

  20. Multiscale recurrence quantification analysis of order recurrence plots

    NASA Astrophysics Data System (ADS)

    Xu, Mengjia; Shang, Pengjian; Lin, Aijing

    2017-03-01

    In this paper, we propose a new method of multiscale recurrence quantification analysis (MSRQA) to analyze the structure of order recurrence plots. The MSRQA is based on order patterns over a range of time scales. Compared with conventional recurrence quantification analysis (RQA), the MSRQA can show richer and more recognizable information on the local characteristics of diverse systems which successfully describes their recurrence properties. Both synthetic series and stock market indexes exhibit their properties of recurrence at large time scales that quite differ from those at a single time scale. Some systems present more accurate recurrence patterns under large time scales. It demonstrates that the new approach is effective for distinguishing three similar stock market systems and showing some inherent differences.

  1. An analysis of file migration in a UNIX supercomputing environment

    NASA Technical Reports Server (NTRS)

    Miller, Ethan L.; Katz, Randy H.

    1992-01-01

    The super computer center at the National Center for Atmospheric Research (NCAR) migrates large numbers of files to and from its mass storage system (MSS) because there is insufficient space to store them on the Cray supercomputer's local disks. This paper presents an analysis of file migration data collected over two years. The analysis shows that requests to the MSS are periodic, with one day and one week periods. Read requests to the MSS account for the majority of the periodicity; as write requests are relatively constant over the course of a week. Additionally, reads show a far greater fluctuation than writes over a day and week since reads are driven by human users while writes are machine-driven.

  2. Stability and Bifurcation Analysis of a Three-Species Food Chain Model with Delay

    NASA Astrophysics Data System (ADS)

    Pal, Nikhil; Samanta, Sudip; Biswas, Santanu; Alquran, Marwan; Al-Khaled, Kamel; Chattopadhyay, Joydev

    In the present paper, we study the effect of gestation delay on a tri-trophic food chain model with Holling type-II functional response. The essential mathematical features of the proposed model are analyzed with the help of equilibrium analysis, stability analysis, and bifurcation theory. Considering time-delay as the bifurcation parameter, the Hopf-bifurcation analysis is carried out around the coexisting equilibrium. The direction of Hopf-bifurcation and the stability of the bifurcating periodic solutions are determined by applying the normal form theory and center manifold theorem. We observe that if the magnitude of the delay is increased, the system loses stability and shows limit cycle oscillations through Hopf-bifurcation. The system also shows the chaotic dynamics via period-doubling bifurcation for further enhancement of time-delay. Our analytical findings are illustrated through numerical simulations.

  3. Crash analysis, statistics & information notebook 2008

    DOT National Transportation Integrated Search

    2008-01-01

    Traditionally crash data is often presented as single fact sheets highlighting a single factor such as Vehicle Type or Road Type. This document will try to show how the risk factors interrelate to produce a crash. Complete detailed analys...

  4. Truth in advertising?-An automobile kinematics problem

    NASA Astrophysics Data System (ADS)

    King, John G.; French, A. P.

    1998-05-01

    An advertisement showing a set of photographs of a car accelerating from rest along a straight road is analyzed. It is found that the times marked on the photographs must be incorrect, and a revised analysis is presented.

  5. Communication and Contraceptive Practices in Adolescent Couples.

    ERIC Educational Resources Information Center

    Polit-O'Hara, Denise; Kahn, Janet R.

    1985-01-01

    Presents a descriptive analysis of couple communication among stable, sexually active adolescent couples (N=83) and the effect of communication on actual contraceptive practices. Results showed couples with good communication were more likely to practice effective contraception. (BH)

  6. Decoding spike timing: the differential reverse correlation method

    PubMed Central

    Tkačik, Gašper; Magnasco, Marcelo O.

    2009-01-01

    It is widely acknowledged that detailed timing of action potentials is used to encode information, for example in auditory pathways; however the computational tools required to analyze encoding through timing are still in their infancy. We present a simple example of encoding, based on a recent model of time-frequency analysis, in which units fire action potentials when a certain condition is met, but the timing of the action potential depends also on other features of the stimulus. We show that, as a result, spike-triggered averages are smoothed so much they do not represent the true features of the encoding. Inspired by this example, we present a simple method, differential reverse correlations, that can separate an analysis of what causes a neuron to spike, and what controls its timing. We analyze with this method the leaky integrate-and-fire neuron and show the method accurately reconstructs the model's kernel. PMID:18597928

  7. Voxel Datacubes for 3D Visualization in Blender

    NASA Astrophysics Data System (ADS)

    Gárate, Matías

    2017-05-01

    The growth of computational astrophysics and the complexity of multi-dimensional data sets evidences the need for new versatile visualization tools for both the analysis and presentation of the data. In this work, we show how to use the open-source software Blender as a three-dimensional (3D) visualization tool to study and visualize numerical simulation results, focusing on astrophysical hydrodynamic experiments. With a datacube as input, the software can generate a volume rendering of the 3D data, show the evolution of a simulation in time, and do a fly-around camera animation to highlight the points of interest. We explain the process to import simulation outputs into Blender using the voxel data format, and how to set up a visualization scene in the software interface. This method allows scientists to perform a complementary visual analysis of their data and display their results in an appealing way, both for outreach and science presentations.

  8. A spectrum fractal feature classification algorithm for agriculture crops with hyper spectrum image

    NASA Astrophysics Data System (ADS)

    Su, Junying

    2011-11-01

    A fractal dimension feature analysis method in spectrum domain for hyper spectrum image is proposed for agriculture crops classification. Firstly, a fractal dimension calculation algorithm in spectrum domain is presented together with the fast fractal dimension value calculation algorithm using the step measurement method. Secondly, the hyper spectrum image classification algorithm and flowchart is presented based on fractal dimension feature analysis in spectrum domain. Finally, the experiment result of the agricultural crops classification with FCL1 hyper spectrum image set with the proposed method and SAM (spectral angle mapper). The experiment results show it can obtain better classification result than the traditional SAM feature analysis which can fulfill use the spectrum information of hyper spectrum image to realize precision agricultural crops classification.

  9. ANSYS-based birefringence property analysis of side-hole fiber induced by pressure and temperature

    NASA Astrophysics Data System (ADS)

    Zhou, Xinbang; Gong, Zhenfeng

    2018-03-01

    In this paper, we theoretically investigate the influences of pressure and temperature on the birefringence property of side-hole fibers with different shapes of holes using the finite element analysis method. A physical mechanism of the birefringence of the side-hole fiber is discussed with the presence of different external pressures and temperatures. The strain field distribution and birefringence values of circular-core, rectangular-core, and triangular-core side-hole fibers are presented. Our analysis shows the triangular-core side-hole fiber has low temperature sensitivity which weakens the cross sensitivity of temperature and strain. Additionally, an optimized structure design of the side-hole fiber is presented which can be used for the sensing application.

  10. Mixed Models and Reduction Techniques for Large-Rotation, Nonlinear Analysis of Shells of Revolution with Application to Tires

    NASA Technical Reports Server (NTRS)

    Noor, A. K.; Andersen, C. M.; Tanner, J. A.

    1984-01-01

    An effective computational strategy is presented for the large-rotation, nonlinear axisymmetric analysis of shells of revolution. The three key elements of the computational strategy are: (1) use of mixed finite-element models with discontinuous stress resultants at the element interfaces; (2) substantial reduction in the total number of degrees of freedom through the use of a multiple-parameter reduction technique; and (3) reduction in the size of the analysis model through the decomposition of asymmetric loads into symmetric and antisymmetric components coupled with the use of the multiple-parameter reduction technique. The potential of the proposed computational strategy is discussed. Numerical results are presented to demonstrate the high accuracy of the mixed models developed and to show the potential of using the proposed computational strategy for the analysis of tires.

  11. Comprehensive Analysis Modeling of Small-Scale UAS Rotors

    NASA Technical Reports Server (NTRS)

    Russell, Carl R.; Sekula, Martin K.

    2017-01-01

    Multicopter unmanned aircraft systems (UAS), or drones, have continued their explosive growth in recent years. With this growth comes demand for increased performance as the limits of existing technologies are reached. In order to better design multicopter UAS aircraft, better performance prediction tools are needed. This paper presents the results of a study aimed at using the rotorcraft comprehensive analysis code CAMRAD II to model a multicopter UAS rotor in hover. Parametric studies were performed to determine the level of fidelity needed in the analysis code inputs to achieve results that match test data. Overall, the results show that CAMRAD II is well suited to model small-scale UAS rotors in hover. This paper presents the results of the parametric studies as well as recommendations for the application of comprehensive analysis codes to multicopter UAS rotors.

  12. Narrow band quantitative and multivariate electroencephalogram analysis of peri-adolescent period

    PubMed Central

    2012-01-01

    Background The peri-adolescent period is a crucial developmental moment of transition from childhood to emergent adulthood. The present report analyses the differences in Power Spectrum (PS) of the Electroencephalogram (EEG) between late childhood (24 children between 8 and 13 years old) and young adulthood (24 young adults between 18 and 23 years old). Results The narrow band analysis of the Electroencephalogram was computed in the frequency range of 0–20 Hz. The analysis of mean and variance suggested that six frequency ranges presented a different rate of maturation at these ages, namely: low delta, delta-theta, low alpha, high alpha, low beta and high beta. For most of these bands the maturation seems to occur later in anterior sites than posterior sites. Correlational analysis showed a lower pattern of correlation between different frequencies in children than in young adults, suggesting a certain asynchrony in the maturation of different rhythms. The topographical analysis revealed similar topographies of the different rhythms in children and young adults. Principal Component Analysis (PCA) demonstrated the same internal structure for the Electroencephalogram of both age groups. Principal Component Analysis allowed to separate four subcomponents in the alpha range. All these subcomponents peaked at a lower frequency in children than in young adults. Conclusions The present approaches complement and solve some of the incertitudes when the classical brain broad rhythm analysis is applied. Children have a higher absolute power than young adults for frequency ranges between 0-20 Hz, the correlation of Power Spectrum (PS) with age and the variance age comparison showed that there are six ranges of frequencies that can distinguish the level of EEG maturation in children and adults. The establishment of maturational order of different frequencies and its possible maturational interdependence would require a complete series including all the different ages. PMID:22920159

  13. Direct Analysis in Real Time by Mass Spectrometric Technique for Determining the Variation in Metabolite Profiles of Cinnamomum tamala Nees and Eberm Genotypes

    PubMed Central

    Singh, Vineeta; Gupta, Atul Kumar; Singh, S. P.; Kumar, Anil

    2012-01-01

    Cinnamomum tamala Nees & Eberm. is an important traditional medicinal plant, mentioned in various ancient literatures such as Ayurveda. Several of its medicinal properties have recently been proved. To characterize diversity in terms of metabolite profiles of Cinnamomum tamala Nees and Eberm genotypes, a newly emerging mass spectral ionization technique direct time in real time (DART) is very helpful. The DART ion source has been used to analyze an extremely wide range of phytochemicals present in leaves of Cinnamomum tamala. Ten genotypes were assessed for the presence of different phytochemicals. Phytochemical analysis showed the presence of mainly terpenes and phenols. These constituents vary in the different genotypes of Cinnamomum tamala. Principal component analysis has also been employed to analyze the DART data of these Cinnamomum genotypes. The result shows that the genotype of Cinnamomum tamala could be differentiated using DART MS data. The active components present in Cinnamomum tamala may be contributing significantly to high amount of antioxidant property of leaves and, in turn, conditional effects for diabetic patients. PMID:22701361

  14. Genotype evaluation of cowpea seeds (Vigna unguiculata) using 1H qNMR combined with exploratory tools and solid-state NMR.

    PubMed

    Alves Filho, Elenilson G; Silva, Lorena M A; Teofilo, Elizita M; Larsen, Flemming H; de Brito, Edy S

    2017-01-01

    The ultimate aim of this study was to apply a non-targeted chemometric analysis (principal component analysis and hierarchical clustering analysis using the heat map approach) of NMR data to investigate the variability of organic compounds in nine genotype cowpea seeds, without any complex pre-treatment. In general, both exploratory tools show that Tvu 233, CE-584, and Setentão genotypes presented higher amount mainly of raffinose and Tvu 382 presented the highest content of choline and least content of raffinose. The evaluation of the aromatic region showed the Setentão genotype with highest content of niacin/vitamin B3 whereas Tvu 382 with lowest amount. To investigate rigid and mobile components in the seeds cotyledon, 13 C CP and SP/MAS solid-state NMR experiments were performed. The cotyledon of the cowpea comprised a rigid part consisting of starch as well as a soft portion made of starch, fatty acids, and protein. The variable contact time experiment suggests the presence of lipid-amylose complexes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  15. Proximate and elemental analysis of five selected medicinal plants of family Solanaceae.

    PubMed

    Hameed, Ishfaq; Hussain, Farrukh

    2015-07-01

    The proximate analysis revealed the presence of ash, moisture, protein, fiber, fats and carbohydrate. ANOVA showed that ash and moisture contents was non significant between the plant parts and phenological stages. Crude protein was non significant between the plant parts and phenological stages except for Datura innoxia parts but not for its phenolgical stages, while crude fats were non significant between the plant parts and phenological stages except for Solanum nigrum and Solanum surattense parts but not for their phenolgical stages. Crude fiber was non significant between the plant parts and phenological stages except for Datura innoxia parts but not for its phenolgical stages. And carbohydrates was non significant between the plant parts and phenological stages except for the phenolgical stages of Solanum surattense and Withania coagulans. The mineral analysis showed the presence of Cr, Zn, Cu, Mn, Fe, Ca, K, Mg and Na in the roots, stems, leaves, flowers and fruits of the plants in three different phenological stages. Only the micro-minerals were present in traces while the macro-minerals were present high quantities as compared to the micro-minerals.

  16. Improved tactile resonance sensor for robotic assisted surgery

    NASA Astrophysics Data System (ADS)

    Oliva Uribe, David; Schoukens, Johan; Stroop, Ralf

    2018-01-01

    This paper presents an improved tactile sensor using a piezoelectric bimorph able to differentiate soft materials with similar mechanical characteristics. The final aim is to develop intelligent surgical tools for brain tumour resection using integrated sensors in order to improve tissue tumour delineation and tissue differentiation. The bimorph sensor is driven using a random phase multisine and the properties of contact between the sensor's tip and a certain load are evaluated by means of the evaluation of the nonparametric FRF. An analysis of the nonlinear contributions is presented to show that the use of a linear model is feasible for the measurement conditions. A series of gelatine phantoms were tested. The tactile sensor is able to identify minimal differences in the consistency of the measured samples considering viscoelastic behaviour. A variance analysis was performed to evaluate the reliability of the sensors and to identify possible error sources due to inconsistencies in the preparation method of the phantoms. The results of the variance analysis are discussed showing that ability of the proposed tactile sensor to perform high quality measurements.

  17. Solid–Liquid Phase Change Driven by Internal Heat Generation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    John Crepeau; Ali s. Siahpush

    2012-07-01

    This article presents results of solid-liquid phase change, the Stefan Problem, where melting is driven internal heat generation, in a cylindrical geometry. The comparison between a quasi-static analytical solution for Stefan numbers less than one and numerical solutions shows good agreement. The computational results of phase change with internal heat generation show how convection cells form in the liquid region. A scale analysis of the same problem shows four distinct regions of the melting process.

  18. Conceptual Design of a Z-Pinch Fusion Propulsion System

    NASA Technical Reports Server (NTRS)

    Adams, Robert; Polsgrove, Tara; Fincher, Sharon; Fabinski, Leo; Maples, Charlotte; Miernik, Janie; Stratham, Geoffrey; Cassibry, Jason; Cortez, Ross; Turner, Matthew; hide

    2010-01-01

    This slide presentation reviews a project that aims to develop a conceptual design for a Z-pinch thruster, that could be applied to develop advanced thruster designs which promise high thrust/high specific impulse propulsion. Overviews shows the concept of the design, which use annular nozzles with deuterium-tritium (D-T) fuel and a Lithium mixture as a cathode, Charts show the engine performance as a function of linear mass, nozzle performance (i.e., plasma segment trajectories), and mission analysis for possible Mars and Jupiter missions using this concept for propulsion. Slides show views of the concepts for the vehicle configuration, thrust coil configuration, the power management system, the structural analysis of the magnetic nozzle, the thermal management system, and the avionics suite,

  19. Acute hepatic encephalopathy presenting as cortical laminar necrosis: case report.

    PubMed

    Choi, Jong Mun; Kim, Yoon Hee; Roh, Sook Young

    2013-01-01

    We report on a 55-year-old man with alcoholic liver cirrhosis who presented with status epilepticus. Laboratory analysis showed markedly elevated blood ammonia. Brain magnetic resonance imaging (MRI) showed widespread cortical signal changes with restricted diffusion, involving both temporo-fronto-parietal cortex, while the perirolandic regions and occipital cortex were uniquely spared. A follow-up brain MRI demonstrated diffuse cortical atrophy with increased signals on T1-weighted images in both the basal ganglia and temporal lobe cortex, representing cortical laminar necrosis. We suggest that the brain lesions, in our case, represent a consequence of toxic effect of ammonia.

  20. Study Pollution Impacts on Upper-Tropospheric Clouds with Aura, CloudSat, and CALIPSO Data

    NASA Technical Reports Server (NTRS)

    Wu, Dong

    2007-01-01

    This viewgraph presentation reviews the impact of pollution on clouds in the Upper Troposphere. Using the data from the Aura Microwave Limb Sounder (MLS), CloudSat, CALIPSO the presentation shows signatures of pollution impacts on clouds in the upper troposphere. The presentation demonstrates the complementary sensitivities of MLS , CloudSat and CALIPSO to upper tropospheric clouds. It also calls for careful analysis required to sort out microphysical changes from dynamical changes.

  1. Telemetry-assisted early detection of STEMI in patients with atypical symptoms by paramedic-performed 12-lead ECG with subsequent cardiological analysis.

    PubMed

    Campo Dell' Orto, Marco; Hamm, Christian; Liebetrau, Christoph; Hempel, Dorothea; Merbs, Reinhold; Cuca, Colleen; Breitkreutz, Raoul

    2017-08-01

    ECG is an essential diagnostic tool in patients with acute coronary syndrome. We aimed to determine how many patients presenting with atypical symptoms for an acute myocardial infarction show ST-segment elevations on prehospital ECG. We also aimed to study the feasibility of telemetric-assisted prehospital ECG analysis. Between April 2010 and February 2011, consecutive emergency patients presenting with atypical symptoms such as nausea, vomiting, atypical chest pain, palpitations, hypertension, syncope, or dizziness were included in the study. After basic measures were completed, a 12-lead ECG was written and telemetrically transmitted to the cardiac center, where it was analyzed by attending physicians. Any identification of an ST-elevation myocardial infarction resulted in patient admission at the closest coronary angiography facility. A total of 313 emergency patients presented with the following symptoms: dyspnea, nausea, vomiting, dizziness/collapse, or acute hypertension. Thirty-four (11%) patients of this cohort were found to show ST-segment elevations on the 12-lead ECG. These patients were directly admitted to the closest coronary catheterization facility rather than the closest hospital. The time required for transmission and analysis of the ECG was 3.6±1.2 min. Telemetry-assisted 12-lead ECG analysis in a prehospital setting may lead to earlier detection of ST-elevation myocardial infarction in patients with atypical symptoms. Thus, a 12-lead ECG should be considered in all prehospital patients both with typical and atypical symptoms.

  2. Portable Life Support Subsystem Thermal Hydraulic Performance Analysis

    NASA Technical Reports Server (NTRS)

    Barnes, Bruce; Pinckney, John; Conger, Bruce

    2010-01-01

    This paper presents the current state of the thermal hydraulic modeling efforts being conducted for the Constellation Space Suit Element (CSSE) Portable Life Support Subsystem (PLSS). The goal of these efforts is to provide realistic simulations of the PLSS under various modes of operation. The PLSS thermal hydraulic model simulates the thermal, pressure, flow characteristics, and human thermal comfort related to the PLSS performance. This paper presents modeling approaches and assumptions as well as component model descriptions. Results from the models are presented that show PLSS operations at steady-state and transient conditions. Finally, conclusions and recommendations are offered that summarize results, identify PLSS design weaknesses uncovered during review of the analysis results, and propose areas for improvement to increase model fidelity and accuracy.

  3. Corrosion Properties of SAC305 Solder in Different Solution of HCl and NaCl

    NASA Astrophysics Data System (ADS)

    Nurwahida, M. Z.; Mukridz, M. M.; Ahmad, A. M.; Muhammad, F. M. N.

    2018-03-01

    Potentiodynamic polarization was used to studied the corrosion properties of SAC305 solder in different solution of 1.0 M HCl and 3.5 wt.% NaCl using the same scanning rate of 1.0 mV/s. The polarization curves indicated that corrosion in NaCl was less severe than in HCl solution based on corrosion current and passivation behavior obtained. Morphology and phases obtained after corrosion using SEM and XRD were analyzed. Microstructure analysis shows the present of compact corrosion product with presence of larger flake for polarization in NaCl compared to HCl. Phases present in XRD analysis confirmed the present of SnO and SnO2 corrosion product for sample from both solutions.

  4. Thermal stress analysis for a wood composite blade. [wind turbines

    NASA Technical Reports Server (NTRS)

    Fu, K. C.; Harb, A.

    1984-01-01

    Heat conduction throughout the blade and the distribution of thermal stresses caused by the temperature distribution were determined for a laminated wood wind turbine blade in both the horizontal and vertical positions. Results show that blade cracking is not due to thermal stresses induced by insulation. A method and practical example of thermal stress analysis for an engineering body of orthotropic materials is presented.

  5. Cross-Linguistic Transfer of Oral Language, Decoding, Phonological Awareness and Reading Comprehension: A Meta-Analysis of the Correlational Evidence

    ERIC Educational Resources Information Center

    Melby-Lervag, Monica; Lervag, Arne

    2011-01-01

    We present a meta-analysis of cross-linguistic transfer of oral language (vocabulary and listening comprehension), phonology (decoding and phonological awareness) and reading comprehension. Our findings show a small meta-correlation between first (L1) and second (L2) oral language and a moderate to large correlation between L1 and L2 phonological…

  6. Show & Tell: A Video Column / Don't Just Gather Data--Use It

    ERIC Educational Resources Information Center

    Fisher, Doug; Frey, Nancy

    2015-01-01

    Schools are awash in data, and teachers are being asked to gather data in a myriad of high-tech and low-tech ways. But gathering is not analyzing, and without analysis there is little reason to gather the data in the first place. Teachers need data-collection systems that lend themselves to rapid analysis and action. This article presents several…

  7. [Morphometric and stereometric analysis of the masticatory muscles in cases of progeny].

    PubMed

    Solov'ev, V A; Golikov, D I; Shinkarenko, T V

    2009-01-01

    The data of microscopic and ultramicroscopric analysis of the muscles of mastication were presented of 12 male patients with progeny. There were determined differentiating peculiarities of muscles fibers of masseter and medial pterygoid in cases of progeny. The results of comperative analysis showed some decreasing of muscular quota and increasing connective tissue's quota; some decreasing muscular fibers' diameters and quantity of blood capillaries; some increasing muscular fibers type I in the muscles of mastication in progeny cases.

  8. Kuhn-Tucker optimization based reliability analysis for probabilistic finite elements

    NASA Technical Reports Server (NTRS)

    Liu, W. K.; Besterfield, G.; Lawrence, M.; Belytschko, T.

    1988-01-01

    The fusion of probability finite element method (PFEM) and reliability analysis for fracture mechanics is considered. Reliability analysis with specific application to fracture mechanics is presented, and computational procedures are discussed. Explicit expressions for the optimization procedure with regard to fracture mechanics are given. The results show the PFEM is a very powerful tool in determining the second-moment statistics. The method can determine the probability of failure or fracture subject to randomness in load, material properties and crack length, orientation, and location.

  9. Microscopic Evaluation of Friction Plug Welds- Correlation to a Processing Analysis

    NASA Technical Reports Server (NTRS)

    Rabenberg, Ellen M.; Chen, Poshou; Gorti, Sridhar

    2017-01-01

    Recently an analysis of dynamic forge load data from the friction plug weld (FPW) process and the corresponding tensile test results showed that good plug welds fit well within an analytically determined processing parameter box. There were, however, some outliers that compromised the predictions. Here the microstructure of the plug weld material is presented in view of the load analysis with the intent of further understanding the FPW process and how it is affected by the grain structure and subsequent mechanical properties.

  10. Vision-sensing image analysis for GTAW process control

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Long, D.D.

    1994-11-01

    Image analysis of a gas tungsten arc welding (GTAW) process was completed using video images from a charge coupled device (CCD) camera inside a specially designed coaxial (GTAW) electrode holder. Video data was obtained from filtered and unfiltered images, with and without the GTAW arc present, showing weld joint features and locations. Data Translation image processing boards, installed in an IBM PC AT 386 compatible computer, and Media Cybernetics image processing software were used to investigate edge flange weld joint geometry for image analysis.

  11. Nonapplicability of linear finite element programs to the stress analysis of tires

    NASA Technical Reports Server (NTRS)

    Durand, M.; Jankovich, E.

    1972-01-01

    A static finite element stress analysis of an inflated radial car tire was carried out. The deformed shape of the sidewall presents outward bulging. The analysis of a homogeneous isotropic toroidal shell shows that the problem is common to all solids of this type. The study suggests that the geometric stiffness due to the inflation pressure has to be taken into account. Also, the resulting large displacements make it necessary for the geometry to be updated at each load step.

  12. Infrared imaging spectroscopy and chemometric tools for in situ analysis of an imiquimod pharmaceutical preparation presented as cream

    NASA Astrophysics Data System (ADS)

    Carneiro, Renato Lajarim; Poppi, Ronei Jesus

    2014-01-01

    In the present work the homogeneity of a pharmaceutical formulation presented as a cream was studied using infrared imaging spectroscopy and chemometric methodologies such as principal component analysis (PCA) and multivariate curve resolution with alternating least squares (MCR-ALS). A cream formulation, presented as an emulsion, was prepared using imiquimod as the active pharmaceutical ingredient (API) and the excipients: water, vaseline, an emulsifier and a carboxylic acid in order to dissolve the API. After exposure at 45 °C during 3 months to perform accelerated stability test, the presence of some crystals was observed, indicating homogeneity problems in the formulation. PCA exploratory analysis showed that the crystal composition was different from the composition of the emulsion, since the score maps presented crystal structures in the emulsion. MCR-ALS estimated the spectra of the crystals and the emulsion. The crystals presented amine and C-H bands, suggesting that the precipitate was a salt formed by carboxylic acid and imiquimod. These results indicate the potential of infrared imaging spectroscopy in conjunction with chemometric methodologies as an analytical tool to ensure the quality of cream formulations in the pharmaceutical industry.

  13. Proximate analyses and predicting HHV of chars obtained from cocracking of petroleum vacuum residue with coal, plastics and biomass.

    PubMed

    Ahmaruzzaman, M

    2008-07-01

    Higher heating value (HHV) and analysis of chars obtained from cocracking of petroleum vacuum residue (XVR) with coal (SC), biomass (BG, CL) and plastics (PP, PS, BL) are important which define the energy content and determine the clean and efficient use of these chars. The main aim of the present study is to analyze the char obtained from cocracking in terms of their proximate analysis data and determination of the HHV of the chars. The char obtained from XVR+PP cocracking showed a HHV of 32.84 MJ/kg, whereas that from CL cracking showed a HHV of 18.52 MJ/kg. The experimentally determined heating values of the char samples obtained from cocracking have been correlated with the theoretical equation based on proximate analysis data. There exists a variety of correlations for predicting HHV from proximate analysis of fuels. Based upon proximate analysis data, the models were tested. The best results show coefficient of determination (R2) of 0.965 and average absolute and bias error of 3.07% and 0.41%, respectively. The heating values obtained from the model were in good agreement with that obtained by experiment. Proximate analysis of the chars obtained from the cocracking of XVR with coal, biomass and plastics showed that there exists a definite interaction of the reactive species, when they were cocracked together.

  14. Evolution and devolution of folkbiological knowledge.

    PubMed

    Wolff, P; Medin, D L; Pankratz, C

    1999-12-07

    In this paper we present evidence in support of the hypothesis that the average person's knowledge about trees, and about the natural world in general, has declined during the 20th century. Our investigations are based on examination of a large sample of written material from the 16th through 20th centuries contained in the Oxford English Dictionary. In Analysis 1, we show a precipitous decline in the use of tree terms after, but not before, the 19th century. In Analysis 2, we analyze tree terms at different levels of organization and show that the decline observed in Analysis 1 occurs for all levels of organization. This second analysis also reveals that during the 16th to 19th centuries tree terms became progressively more specific, suggesting that during these periods knowledge about trees increased. In Analysis 3, we show similar rates of decline in other folkbiological categories, indicating that the change in tree terms reflects a general decline in knowledge about living kinds. Also in Analysis 3, we show that several non-biological categories have experienced evolution during the 20th century, indicating that the declines in the 20th century for folkbiological categories are not an inevitable outcome of the corpus. Finally, Analysis 4 also shows declines in the frequency of quotations for which the tree term was not the topic of the sentence, and thus incidental to the purposes of the writer. The results from Analysis 4 reassure us that the results from Analyses 1-3 were not solely due to change in the aims and purposes of writers over the centuries. In sum, the analyses indicate that in the domain of trees, there has been a long and sustained period of conceptual evolution followed by a recent pronounced period of devolution.

  15. The role of color information on object recognition: a review and meta-analysis.

    PubMed

    Bramão, Inês; Reis, Alexandra; Petersson, Karl Magnus; Faísca, Luís

    2011-09-01

    In this study, we systematically review the scientific literature on the effect of color on object recognition. Thirty-five independent experiments, comprising 1535 participants, were included in a meta-analysis. We found a moderate effect of color on object recognition (d=0.28). Specific effects of moderator variables were analyzed and we found that color diagnosticity is the factor with the greatest moderator effect on the influence of color in object recognition; studies using color diagnostic objects showed a significant color effect (d=0.43), whereas a marginal color effect was found in studies that used non-color diagnostic objects (d=0.18). The present study did not permit the drawing of specific conclusions about the moderator effect of the object recognition task; while the meta-analytic review showed that color information improves object recognition mainly in studies using naming tasks (d=0.36), the literature review revealed a large body of evidence showing positive effects of color information on object recognition in studies using a large variety of visual recognition tasks. We also found that color is important for the ability to recognize artifacts and natural objects, to recognize objects presented as types (line-drawings) or as tokens (photographs), and to recognize objects that are presented without surface details, such as texture or shadow. Taken together, the results of the meta-analysis strongly support the contention that color plays a role in object recognition. This suggests that the role of color should be taken into account in models of visual object recognition. Copyright © 2011 Elsevier B.V. All rights reserved.

  16. Leaching of Zinc Sulfide by Thiobacillus ferrooxidans: Bacterial Oxidation of the Sulfur Product Layer Increases the Rate of Zinc Sulfide Dissolution at High Concentrations of Ferrous Ions

    PubMed Central

    Fowler, T. A.; Crundwell, F. K.

    1999-01-01

    This paper reports the results of leaching experiments conducted with and without Thiobacillus ferrooxidans at the same conditions in solution. The extent of leaching of ZnS with bacteria is significantly higher than that without bacteria at high concentrations of ferrous ions. A porous layer of elemental sulfur is present on the surfaces of the chemically leached particles, while no sulfur is present on the surfaces of the bacterially leached particles. The analysis of the data using the shrinking-core model shows that the chemical leaching of ZnS is limited by the diffusion of ferrous ions through the sulfur product layer at high concentrations of ferrous ions. The analysis of the data shows that diffusion through the product layer does not limit the rate of dissolution when bacteria are present. This suggests that the action of T. ferrooxidans in oxidizing the sulfur formed on the particle surface is to remove the barrier to diffusion by ferrous ions. PMID:10583978

  17. Human brain networks in physiological aging: a graph theoretical analysis of cortical connectivity from EEG data.

    PubMed

    Vecchio, Fabrizio; Miraglia, Francesca; Bramanti, Placido; Rossini, Paolo Maria

    2014-01-01

    Modern analysis of electroencephalographic (EEG) rhythms provides information on dynamic brain connectivity. To test the hypothesis that aging processes modulate the brain connectivity network, EEG recording was conducted on 113 healthy volunteers. They were divided into three groups in accordance with their ages: 36 Young (15-45 years), 46 Adult (50-70 years), and 31 Elderly (>70 years). To evaluate the stability of the investigated parameters, a subgroup of 10 subjects underwent a second EEG recording two weeks later. Graph theory functions were applied to the undirected and weighted networks obtained by the lagged linear coherence evaluated by eLORETA on cortical sources. EEG frequency bands of interest were: delta (2-4 Hz), theta (4-8 Hz), alpha1 (8-10.5 Hz), alpha2 (10.5-13 Hz), beta1 (13-20 Hz), beta2 (20-30 Hz), and gamma (30-40 Hz). The spectral connectivity analysis of cortical sources showed that the normalized Characteristic Path Length (λ) presented the pattern Young > Adult>Elderly in the higher alpha band. Elderly also showed a greater increase in delta and theta bands than Young. The correlation between age and λ showed that higher ages corresponded to higher λ in delta and theta and lower in the alpha2 band; this pattern reflects the age-related modulation of higher (alpha) and decreased (delta) connectivity. The Normalized Clustering coefficient (γ) and small-world network modeling (σ) showed non-significant age-modulation. Evidence from the present study suggests that graph theory can aid in the analysis of connectivity patterns estimated from EEG and can facilitate the study of the physiological and pathological brain aging features of functional connectivity networks.

  18. Apatinib promotes apoptosis of the SMMC-7721 hepatocellular carcinoma cell line via the PI3K/Akt pathway.

    PubMed

    Zhang, Hua; Cao, Yumei; Chen, Yuru; Li, Guangxi; Yu, Hanshu

    2018-04-01

    The present study investigated the inhibitory effects of apatinib on the proliferation of the SMMC-7721 hepatocellular carcinoma cell line to explore the possible mechanism. The MTT assay was used to detect the inhibitory effects of the different concentrations of apatinib on the proliferation of SMMC-7721 cells. Annexin V/PI double staining was performed to investigate the effects of apatinib on the apoptosis of SMMC-7721 cells. Expression of the apoptosis-related genes Bcl-2, Bax and caspase-9 after apatinib treatment was detected by reverse transcription-quantitative PCR (RT-qPCR) and western blot analysis. Expression of the PI3K, p-PI3K, Akt and p-Akt proteins after apatinib treatment was detected using western blot analysis. The MTT results showed that apatinib inhibited the in vitro proliferation of SMMC-7721 cells. Annexin V/PI double staining showed that apatinib induced the apoptosis of SMMC-7721 cells in a concentration-dependent manner. Results of RT-qPCR and western blot analysis showed that apatinib was able to induce the expression of pro-apoptotic genes Bax and caspase-9 and inhibited the expression of anti-apoptotic gene Bcl-2 . In addition, the western blot analysis revealed that p-PI3K and p-Akt was significantly decreased following apatinib treatment, while no significant differences were found in the total protein levels of PI3K and Akt. The results of the present show that apatinib is capable of promoting the apoptosis of SMMC-7721 cells by inhibiting the PI3K/Akt signal transduction pathway, upregulating the expression of pro-apoptotic genes Bax and caspase-9 , and downregulating the expression level of the anti-apoptotic gene Bcl-2 .

  19. Meta-analysis of the performance variation in broilers experimentally challenged by Eimeria spp.

    PubMed

    Kipper, Marcos; Andretta, Ines; Lehnen, Cheila Roberta; Lovatto, Paulo Alberto; Monteiro, Silvia Gonzalez

    2013-09-01

    A meta-analysis was carried out to (1) study the relation of the variation in feed intake and weight gain in broilers infected with Eimeria acervulina, Eimeria maxima, Eimeria tenella, or a Pool of Eimeria species, and (2) to identify and to quantify the effects involved in the infection. A database of articles addressing the experimental infection with Coccidia in broilers was developed. These publications must present results of animal performance (weight gain, feed intake, and feed conversion ratio). The database was composed by 69 publications, totalling around 44 thousand animals. Meta-analysis followed three sequential analyses: graphical, correlation, and variance-covariance. The feed intake of the groups challenged by E. acervulina and E. tenella did not differ (P>0.05) to the control group. However, the feed intake in groups challenged by E. maxima and Pool showed an increase of 8% and 5% (P<0.05) in relation to the control group. Challenged groups presented a decrease (P<0.05) in weight gain compared with control groups. All challenged groups showed a reduction in weight gain, even when there was no reduction (P<0.05) in feed intake (adjustment through variance-covariance analysis). The feed intake variation in broilers infected with E. acervulina, E. maxima, E. tenella, or Pool showed a quadratic (P<0.05) influence over the variation in weight gain. In relation to the isolated effects, the challenges have an impact of less than 1% over the variance in feed intake and weight gain. However, the magnitude of the effects varied with Eimeria species, animal age, sex, and genetic line. In general the age effect is superior to the challenge effect, showing that age at the challenge is important to determine the impact of Eimeria infection. Copyright © 2013 Elsevier B.V. All rights reserved.

  20. Fibre-Reinforced Adhesive for Structure Anchoring

    NASA Astrophysics Data System (ADS)

    Barnat, J.; Bajer, M.

    2015-11-01

    The topic of this paper is the glue-concrete interface of bonded anchors loaded by tension force. The paper is closely focused on bond strength experiments using high strength concrete up to class C50/60 or higher together with pure epoxy resin and fibre-reinforced resin. The goal of this research is to find the limits of the effective use of such glue types in high performance concrete, and also to verify the most commonly used design methods for bonded anchors. The presented research includes experimental analysis of the glue-concrete interface and the influence of its parameters on anchor behaviour. The presented analysis shows some problems of the 'separated failure modes' approach and also presents experimentally verified bond strength values obtained for the currently most widespread glue types. Results of fibre reinforced epoxy resin are also presented in this paper.

  1. Array-CGH analysis in Rwandan patients presenting development delay/intellectual disability with multiple congenital anomalies.

    PubMed

    Uwineza, Annette; Caberg, Jean-Hubert; Hitayezu, Janvier; Hellin, Anne Cecile; Jamar, Mauricette; Dideberg, Vinciane; Rusingiza, Emmanuel K; Bours, Vincent; Mutesa, Leon

    2014-07-12

    Array-CGH is considered as the first-tier investigation used to identify copy number variations. Right now, there is no available data about the genetic etiology of patients with development delay/intellectual disability and congenital malformation in East Africa. Array comparative genomic hybridization was performed in 50 Rwandan patients with development delay/intellectual disability and multiple congenital abnormalities, using the Agilent's 180 K microarray platform. Fourteen patients (28%) had a global development delay whereas 36 (72%) patients presented intellectual disability. All patients presented multiple congenital abnormalities. Clinically significant copy number variations were found in 13 patients (26%). Size of CNVs ranged from 0,9 Mb to 34 Mb. Six patients had CNVs associated with known syndromes, whereas 7 patients presented rare genomic imbalances. This study showed that CNVs are present in African population and show the importance to implement genetic testing in East-African countries.

  2. SELECT RESEARCH GROUP IN AIR POLLUTION METEOROLOGY

    EPA Science Inventory

    Six individual investigators, who have conducted different but related meteorological research, present in-depth technical reviews of their work. Prime conclusions are that (1) a scale analysis shows that different models are necessary for meteorological processes on urban, regio...

  3. Adding results to a meta-analysis: Theory and example

    NASA Astrophysics Data System (ADS)

    Willson, Victor L.

    Meta-analysis has been used as a research method to describe bodies of research data. It promotes hypothesis formation and the development of science education laws. A function overlooked, however, is the role it plays in updating research. Methods to integrate new research with meta-analysis results need explication. A procedure is presented using Bayesian analysis. Research in science education attitude correlation with achievement has been published after a recent meta-analysis of the topic. The results show how new findings complement the previous meta-analysis and extend its conclusions. Additional methodological questions adddressed are how studies are to be weighted, which variables are to be examined, and how often meta-analysis are to be updated.

  4. Intrinsic, stimulus-driven and task-dependent connectivity in human auditory cortex.

    PubMed

    Häkkinen, Suvi; Rinne, Teemu

    2018-06-01

    A hierarchical and modular organization is a central hypothesis in the current primate model of auditory cortex (AC) but lacks validation in humans. Here we investigated whether fMRI connectivity at rest and during active tasks is informative of the functional organization of human AC. Identical pitch-varying sounds were presented during a visual discrimination (i.e. no directed auditory attention), pitch discrimination, and two versions of pitch n-back memory tasks. Analysis based on fMRI connectivity at rest revealed a network structure consisting of six modules in supratemporal plane (STP), temporal lobe, and inferior parietal lobule (IPL) in both hemispheres. In line with the primate model, in which higher-order regions have more longer-range connections than primary regions, areas encircling the STP module showed the highest inter-modular connectivity. Multivariate pattern analysis indicated significant connectivity differences between the visual task and rest (driven by the presentation of sounds during the visual task), between auditory and visual tasks, and between pitch discrimination and pitch n-back tasks. Further analyses showed that these differences were particularly due to connectivity modulations between the STP and IPL modules. While the results are generally in line with the primate model, they highlight the important role of human IPL during the processing of both task-irrelevant and task-relevant auditory information. Importantly, the present study shows that fMRI connectivity at rest, during presentation of sounds, and during active listening provides novel information about the functional organization of human AC.

  5. Measuring pilot workload in a motion base simulator. III - Synchronous secondary task

    NASA Technical Reports Server (NTRS)

    Kantowitz, Barry H.; Bortolussi, Michael R.; Hart, Sandra G.

    1987-01-01

    This experiment continues earlier research of Kantowitz et al. (1983) conducted in a GAT-1 motion-base trainer to evaluate choice-reaction secondary tasks as measures of pilot work load. The earlier work used an asynchronous secondary task presented every 22 sec regardless of flying performance. The present experiment uses a synchronous task presented only when a critical event occurred on the flying task. Both two- and four-choice visual secondary tasks were investigated. Analysis of primary flying-task results showed no decrement in error for altitude, indicating that the key assumption necessary for using a choice secondary task was satisfied. Reaction times showed significant differences between 'easy' and 'hard' flight scenarios as well as the ability to discriminate among flight tasks.

  6. The Effectiveness of Worked Examples Associated with Presentation Format and Prior Knowledge: A Web-Based Experiment

    ERIC Educational Resources Information Center

    Hsiao, E-Ling

    2010-01-01

    The aim of this study is to explore whether presentation format and prior knowledge affect the effectiveness of worked examples. The experiment was conducted through a specially designed online instrument. A 2X2X3 factorial before-and-after design was conducted. Three-way ANOVA was employed for data analysis. The result showed first, that prior…

  7. Beyond harmonic sounds in a simple model for birdsong production.

    PubMed

    Amador, Ana; Mindlin, Gabriel B

    2008-12-01

    In this work we present an analysis of the dynamics displayed by a simple bidimensional model of labial oscillations during birdsong production. We show that the same model capable of generating tonal sounds can present, for a wide range of parameters, solutions which are spectrally rich. The role of physiologically sensible parameters is discussed in each oscillatory regime, allowing us to interpret previously reported data.

  8. The statistical analysis of global climate change studies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hardin, J.W.

    1992-01-01

    The focus of this work is to contribute to the enhancement of the relationship between climatologists and statisticians. The analysis of global change data has been underway for many years by atmospheric scientists. Much of this analysis includes a heavy reliance on statistics and statistical inference. Some specific climatological analyses are presented and the dependence on statistics is documented before the analysis is undertaken. The first problem presented involves the fluctuation-dissipation theorem and its application to global climate models. This problem has a sound theoretical niche in the literature of both climate modeling and physics, but a statistical analysis inmore » which the data is obtained from the model to show graphically the relationship has not been undertaken. It is under this motivation that the author presents this problem. A second problem concerning the standard errors in estimating global temperatures is purely statistical in nature although very little materials exists for sampling on such a frame. This problem not only has climatological and statistical ramifications, but political ones as well. It is planned to use these results in a further analysis of global warming using actual data collected on the earth. In order to simplify the analysis of these problems, the development of a computer program, MISHA, is presented. This interactive program contains many of the routines, functions, graphics, and map projections needed by the climatologist in order to effectively enter the arena of data visualization.« less

  9. Retrospective Analysis of Patient Presentations at the Sydney (Australia) Royal Easter Show from 2012 to 2014.

    PubMed

    Crabtree, Nathan; Mo, Shirley; Ong, Leon; Jegathees, Thuvarahan; Wei, Daniel; Fahey, David; Liu, Jia Jenny

    2017-04-01

    Introduction Comprehensive studies on the relationship between patient demographics and subsequent treatment and disposition at a single mass-gathering event are lacking. The Sydney Royal Easter Show (SRES; Sydney Olympic Park, New South Wales, Australia) is an annual, 14-day, agricultural mass-gathering event occurring around the Easter weekend, attracting more than 800,000 patrons per year. In this study, patient records from the SRES were analyzed to examine relationships between weather, crowd size, day of week, and demographics on treatment and disposition. This information would help to predict factors affecting patient treatment and disposition to guide ongoing training of first responders and to evaluate the appropriateness of staffing skills mix at future events. Hypothesis Patient demographics, environmental factors, and attendance would influence the nature and severity of presentations at the SRES, which would influence staffing requirements. A retrospective analysis of 4,141 patient record forms was performed for patients who presented to St John Ambulance (Australian Capital Territory, Australia) at the SRES between 2012 and 2014 inclusive. Presentation type was classified using a previously published minimum data set. Data on weather and crowd size were obtained from the Australian Bureau of Meteorology (Melbourne, Victoria, Australia) and the SRES, respectively. Statistical analyses were performed using SPSS v22 (IBM; Armonk, New York USA). Between 2012 to 2014, over 2.5 million people attended the SRES with 4,141 patients treated onsite. As expected, the majority of presentations were injuries (49%) and illnesses (46%). Although patient demographics and presentation types did not change over time, the duration of treatment increased. A higher proportion of patients were discharged to hospital or home compared to the proportion of patients discharged back to the event. Patients from rural/regional locations (accounting for 15% of all patients) were more likely to require advanced treatment, health professional review, and were more likely to be discharged to hospital or home rather than discharged back to the event. Extremes of temperature were associated with a lower crowd size and higher patient presentation rate (PPR), but had no impact on transfer or referral rates to hospital. This study demonstrated that analyses of patient presentations at an agricultural show provide unique insights on weather, attendance, and demographic features that correlated with treatment and disposition. These data can help guide organizers with information on how to better staff and train health care providers at future mass-gathering events of this type. Crabtree N , Mo S , Ong L , Jegathees T , Wei D , Fahey D , Liu J . Retrospective analysis of patient presentations at the Sydney (Australia) Royal Easter Show from 2012 to 2014. Prehosp Disaster Med. 2017;32(2)187-194.

  10. Risk Analysis of a Fuel Storage Terminal Using HAZOP and FTA

    PubMed Central

    Baixauli-Pérez, Mª Piedad

    2017-01-01

    The size and complexity of industrial chemical plants, together with the nature of the products handled, means that an analysis and control of the risks involved is required. This paper presents a methodology for risk analysis in chemical and allied industries that is based on a combination of HAZard and OPerability analysis (HAZOP) and a quantitative analysis of the most relevant risks through the development of fault trees, fault tree analysis (FTA). Results from FTA allow prioritizing the preventive and corrective measures to minimize the probability of failure. An analysis of a case study is performed; it consists in the terminal for unloading chemical and petroleum products, and the fuel storage facilities of two companies, in the port of Valencia (Spain). HAZOP analysis shows that loading and unloading areas are the most sensitive areas of the plant and where the most significant danger is a fuel spill. FTA analysis indicates that the most likely event is a fuel spill in tank truck loading area. A sensitivity analysis from the FTA results show the importance of the human factor in all sequences of the possible accidents, so it should be mandatory to improve the training of the staff of the plants. PMID:28665325

  11. Risk Analysis of a Fuel Storage Terminal Using HAZOP and FTA.

    PubMed

    Fuentes-Bargues, José Luis; González-Cruz, Mª Carmen; González-Gaya, Cristina; Baixauli-Pérez, Mª Piedad

    2017-06-30

    The size and complexity of industrial chemical plants, together with the nature of the products handled, means that an analysis and control of the risks involved is required. This paper presents a methodology for risk analysis in chemical and allied industries that is based on a combination of HAZard and OPerability analysis (HAZOP) and a quantitative analysis of the most relevant risks through the development of fault trees, fault tree analysis (FTA). Results from FTA allow prioritizing the preventive and corrective measures to minimize the probability of failure. An analysis of a case study is performed; it consists in the terminal for unloading chemical and petroleum products, and the fuel storage facilities of two companies, in the port of Valencia (Spain). HAZOP analysis shows that loading and unloading areas are the most sensitive areas of the plant and where the most significant danger is a fuel spill. FTA analysis indicates that the most likely event is a fuel spill in tank truck loading area. A sensitivity analysis from the FTA results show the importance of the human factor in all sequences of the possible accidents, so it should be mandatory to improve the training of the staff of the plants.

  12. Association of the 5HTR2A gene with suicidal behavior: CASE-control study and updated meta-analysis

    PubMed Central

    2013-01-01

    Background The polymorphism rs6313 (T102C) has been associated with suicidal behavior in case–control and meta-analysis studies, but results and conclusions remain controversial. The aim of the present study was to examine the association between T102C with suicidal behavior in a case–control study and, to assess the combined evidence – this case–control study and available data from other related studies – we carried out a meta-analysis. Methods We conducted a case–control study that included 161 patients with suicide attempts and 244 controls; we then performed a meta-analysis. The following models were evaluated in the meta-analysis: A) C allele vs T allele; B) T allele vs C allele; C) Caucasian population, D) Asian population, and E) suicide attempters with schizophrenia. Results We found an association between attempted suicide and control participants for genotype (χ2=6.28, p=0.04, df=2) and allele (χ2=6.17, p=0.01, df=1, OR 1.48 95% IC: 1.08-2.03) frequencies in the case–control study. The meta-analysis, comprising 23 association studies (including the present one), showed that the rs6313 polymorphism is not associated with suicidal behavior for the following comparisons:T allele vs C allele (OR: 1.03; 95% CI 0.93-1.13; p(Z)=0.44); C allele vs T allele: (OR:0.99; 95% CI: 0.90-1.08; p(Z)=0.22); Caucasians (OR:1.09; 95% CI: 0.96-1.23), and Asians (OR:0.96; 95% CI: 0.84-1.09). Conclusion Our results showed association between the rs6313 (T102C) polymorphism and suicidal behavior in the case–control study. However, the meta-analysis showed no evidence of association. Therefore, more studies are necessary to determine conclusively an association between T102C and suicidal behavior. PMID:23311440

  13. Rapid quality assessment of Radix Aconiti Preparata using direct analysis in real time mass spectrometry.

    PubMed

    Zhu, Hongbin; Wang, Chunyan; Qi, Yao; Song, Fengrui; Liu, Zhiqiang; Liu, Shuying

    2012-11-08

    This study presents a novel and rapid method to identify chemical markers for the quality control of Radix Aconiti Preparata, a world widely used traditional herbal medicine. In the method, the samples with a fast extraction procedure were analyzed using direct analysis in real time mass spectrometry (DART MS) combined with multivariate data analysis. At present, the quality assessment approach of Radix Aconiti Preparata was based on the two processing methods recorded in Chinese Pharmacopoeia for the purpose of reducing the toxicity of Radix Aconiti and ensuring its clinical therapeutic efficacy. In order to ensure the safety and effectivity in clinical use, the processing degree of Radix Aconiti should be well controlled and assessed. In the paper, hierarchical cluster analysis and principal component analysis were performed to evaluate the DART MS data of Radix Aconiti Preparata samples in different processing times. The results showed that the well processed Radix Aconiti Preparata, unqualified processed and the raw Radix Aconiti could be clustered reasonably corresponding to their constituents. The loading plot shows that the main chemical markers having the most influence on the discrimination amongst the qualified and unqualified samples were mainly some monoester diterpenoid aconitines and diester diterpenoid aconitines, i.e. benzoylmesaconine, hypaconitine, mesaconitine, neoline, benzoylhypaconine, benzoylaconine, fuziline, aconitine and 10-OH-mesaconitine. The established DART MS approach in combination with multivariate data analysis provides a very flexible and reliable method for quality assessment of toxic herbal medicine. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. Analysis of perceived risk among construction workers: a cross-cultural study and reflection on the Hofstede model.

    PubMed

    Martinez-Fiestas, Myriam; Rodríguez-Garzón, Ignacio; Delgado-Padial, Antonio; Lucas-Ruiz, Valeriano

    2017-09-01

    This article presents a cross-cultural study on perceived risk in the construction industry. Worker samples from three different countries were studied: Spain, Peru and Nicaragua. The main goal was to explain how construction workers perceive their occupational hazard and to analyze how this is related to their national culture. The model used to measure perceived risk was the psychometric paradigm. The results show three very similar profiles, indicating that risk perception is independent of nationality. A cultural analysis was conducted using the Hofstede model. The results of this analysis and the relation to perceived risk showed that risk perception in construction is independent of national culture. Finally, a multiple lineal regression analysis was conducted to determine what qualitative attributes could predict the global quantitative size of risk perception. All of the findings have important implications regarding the management of safety in the workplace.

  15. Impacts of a flash flood on drinking water quality: case study of areas most affected by the 2012 Beijing flood.

    PubMed

    Sun, Rubao; An, Daizhi; Lu, Wei; Shi, Yun; Wang, Lili; Zhang, Can; Zhang, Ping; Qi, Hongjuan; Wang, Qiang

    2016-02-01

    In this study, we present a method for identifying sources of water pollution and their relative contributions in pollution disasters. The method uses a combination of principal component analysis and factor analysis. We carried out a case study in three rural villages close to Beijing after torrential rain on July 21, 2012. Nine water samples were analyzed for eight parameters, namely turbidity, total hardness, total dissolved solids, sulfates, chlorides, nitrates, total bacterial count, and total coliform groups. All of the samples showed different degrees of pollution, and most were unsuitable for drinking water as concentrations of various parameters exceeded recommended thresholds. Principal component analysis and factor analysis showed that two factors, the degree of mineralization and agricultural runoff, and flood entrainment, explained 82.50% of the total variance. The case study demonstrates that this method is useful for evaluating and interpreting large, complex water-quality data sets.

  16. Large scale nanoparticle screening for small molecule analysis in laser desorption ionization mass spectrometry

    DOE PAGES

    Yagnik, Gargey B.; Hansen, Rebecca L.; Korte, Andrew R.; ...

    2016-08-30

    Nanoparticles (NPs) have been suggested as efficient matrixes for small molecule profiling and imaging by laser-desorption ionization mass spectrometry (LDI-MS), but so far there has been no systematic study comparing different NPs in the analysis of various classes of small molecules. Here, we present a large scale screening of 13 NPs for the analysis of two dozen small metabolite molecules. Many NPs showed much higher LDI efficiency than organic matrixes in positive mode and some NPs showed comparable efficiencies for selected analytes in negative mode. Our results suggest that a thermally driven desorption process is a key factor for metalmore » oxide NPs, but chemical interactions are also very important, especially for other NPs. Furthermore, the screening results provide a useful guideline for the selection of NPs in the LDI-MS analysis of small molecules.« less

  17. Large scale nanoparticle screening for small molecule analysis in laser desorption ionization mass spectrometry

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yagnik, Gargey B.; Hansen, Rebecca L.; Korte, Andrew R.

    Nanoparticles (NPs) have been suggested as efficient matrixes for small molecule profiling and imaging by laser-desorption ionization mass spectrometry (LDI-MS), but so far there has been no systematic study comparing different NPs in the analysis of various classes of small molecules. Here, we present a large scale screening of 13 NPs for the analysis of two dozen small metabolite molecules. Many NPs showed much higher LDI efficiency than organic matrixes in positive mode and some NPs showed comparable efficiencies for selected analytes in negative mode. Our results suggest that a thermally driven desorption process is a key factor for metalmore » oxide NPs, but chemical interactions are also very important, especially for other NPs. Furthermore, the screening results provide a useful guideline for the selection of NPs in the LDI-MS analysis of small molecules.« less

  18. Isolation, sequence, and characterization of the Cercospora nicotianae phytoene dehydrogenase gene.

    PubMed Central

    Ehrenshaft, M; Daub, M E

    1994-01-01

    We have cloned and sequenced the Cercospora nicotianae gene for the carotenoid biosynthetic enzyme phytoene dehydrogenase. Analysis of the derived amino acid sequence revealed it has greater than 50% identity with its counterpart in Neurospora crassa and approximately 30% identity with prokaryotic phytoene dehydrogenases and is related, but more distantly, to phytoene dehydrogenases from plants and cyanobacteria. Our analysis confirms that phytoene dehydrogenase proteins fall into two groups: those from plants and cyanobacteria and those from eukaryotic and noncyanobacter prokaryotic microbes. Southern analysis indicated that the C. nicotianae phytoene dehydrogenase gene is present in a single copy. Extraction of beta-carotene, the sole carotenoid accumulated by C. nicotianae, showed that both light- and dark-grown cultures synthesize carotenoids, but higher levels accumulate in the light. Northern (RNA) analysis of poly(A)+ RNA, however, showed no differential accumulation of phytoene dehydrogenase mRNA between light- and dark-grown fungal cultures. Images PMID:8085820

  19. Contribution of the graded region of a HgCdTe diode to its saturation current

    NASA Technical Reports Server (NTRS)

    Schacham, S. E.; Finkman, E.

    1990-01-01

    Experimental results show that the contribution of the graded region to the current of Hg(1-x)Cd(x)Te diodes is not negligible, as compared to that of the p type bulk. The theoretical analysis reveals the influence of the electric field present outside the depletion region on the current generated by the graded region. The analysis shows the importance of the lifetime profile in the graded region, which is a function of the specific recombination mechanism and its dependence on the local dopant concentration. The effect of parameters such as substrate concentration, surface concentration, and junction depth on this current is discussed.

  20. Retinal status analysis method based on feature extraction and quantitative grading in OCT images.

    PubMed

    Fu, Dongmei; Tong, Hejun; Zheng, Shuang; Luo, Ling; Gao, Fulin; Minar, Jiri

    2016-07-22

    Optical coherence tomography (OCT) is widely used in ophthalmology for viewing the morphology of the retina, which is important for disease detection and assessing therapeutic effect. The diagnosis of retinal diseases is based primarily on the subjective analysis of OCT images by trained ophthalmologists. This paper describes an OCT images automatic analysis method for computer-aided disease diagnosis and it is a critical part of the eye fundus diagnosis. This study analyzed 300 OCT images acquired by Optovue Avanti RTVue XR (Optovue Corp., Fremont, CA). Firstly, the normal retinal reference model based on retinal boundaries was presented. Subsequently, two kinds of quantitative methods based on geometric features and morphological features were proposed. This paper put forward a retinal abnormal grading decision-making method which was used in actual analysis and evaluation of multiple OCT images. This paper showed detailed analysis process by four retinal OCT images with different abnormal degrees. The final grading results verified that the analysis method can distinguish abnormal severity and lesion regions. This paper presented the simulation of the 150 test images, where the results of analysis of retinal status showed that the sensitivity was 0.94 and specificity was 0.92.The proposed method can speed up diagnostic process and objectively evaluate the retinal status. This paper aims on studies of retinal status automatic analysis method based on feature extraction and quantitative grading in OCT images. The proposed method can obtain the parameters and the features that are associated with retinal morphology. Quantitative analysis and evaluation of these features are combined with reference model which can realize the target image abnormal judgment and provide a reference for disease diagnosis.

  1. 13C labeling analysis of sugars by high resolution-mass spectrometry for metabolic flux analysis.

    PubMed

    Acket, Sébastien; Degournay, Anthony; Merlier, Franck; Thomasset, Brigitte

    2017-06-15

    Metabolic flux analysis is particularly complex in plant cells because of highly compartmented metabolism. Analysis of free sugars is interesting because it provides data to define fluxes around hexose, pentose, and triose phosphate pools in different compartment. In this work, we present a method to analyze the isotopomer distribution of free sugars labeled with carbon 13 using a liquid chromatography-high resolution mass spectrometry, without derivatized procedure, adapted for Metabolic flux analysis. Our results showed a good sensitivity, reproducibility and better accuracy to determine isotopic enrichments of free sugars compared to our previous methods [5, 6]. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Analysis Tools in Geant4 10.2 and 10.3

    NASA Astrophysics Data System (ADS)

    Hřivnáčová, I.; Barrand, G.

    2017-10-01

    A new analysis category based on g4tools was added in Geant4 release 9.5 (2011). The aim was to provide users with a lightweight analysis tool available as part of the Geant4 installation without the need to link to an external analysis package. It has progressively been included in all Geant4 examples. Frequent questions in the Geant4 users forum show its increasing popularity in the Geant4 users community. In this presentation, we will give a brief overview of g4tools and the analysis category. We report on new developments since our CHEP 2013 contribution as well as mention upcoming new features.

  3. Structural and functional analysis of 5S rRNA in Saccharomyces cerevisiae

    PubMed Central

    Kiparisov, S.; Sergiev, P. V.; Dontsova, O. A.; Petrov, A.; Meskauskas, A.; Dinman, J. D.

    2005-01-01

    5S rRNA extends from the central protuberance of the large ribosomal subunit, through the A-site finger, and down to the GTPase-associated center. Here, we present a structure-function analysis of seven 5S rRNA alleles which are sufficient for viability in the yeast Saccharomyces cerevisiae when expressed in the absence of wild-type 5S rRNAs, and extend this analysis using a large bank of mutant alleles that show semidominant phenotypes in the presence of wild-type 5S rRNA. This analysis supports the hypothesis that 5S rRNA serves to link together several different functional centers of the ribosome. Data are also presented which suggest that in eukaryotic genomes selection has favored the maintenance of multiple alleles of 5S rRNA, and that these may provide cells with a mechanism to post-transcriptionally regulate gene expression. PMID:16047201

  4. Dynamic response of a fiber-optic ring resonator: Analysis with influences of light-source parameters

    NASA Astrophysics Data System (ADS)

    Seraji, Faramarz E.

    2009-03-01

    In practice, dynamic behavior of fiber-optic ring resonator (FORR) appears as a detrimental factor to influence the transmission response of the FORR. This paper presents dynamic response analysis of the FORR by considering phase modulation of the FORR loop and sinewave modulation of input signal applied to the FORR from a laser diode. The analysis investigates the influences of modulation frequency and amplitude modulation index of laser diode, loop delay time of the FORR, phase angle between FM and AM response of laser diode, and laser diode line-width on dynamic response of the FORR. The analysis shows that the transient response of the FORR strongly depends on the product of modulation frequency and loop delay time, coupling and transmission coefficients of the FORR. The analyses presented here may have applications in optical systems employing an FORR with a laser diode source.

  5. Automotive manufacturing assessment system. Volume IV: engine manufacturing analysis. Final report Jun 77-Aug 78

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Taylor, T. Jr

    Volume IV represents the results of one of four major study areas under the Automotive Manufacturing Assessment System (AMAS) sponsored by the DOT/Transportation Systems Center. AMAS was designed to assist in the evaluation of industry's capability to produce fuel efficient vehicles. An analysis of automotive engine manufacturing was conducted in order to determine the impact of regulatory changes on tooling costs and the production process. The 351W CID V-8 engine at Ford's Windsor No. 1 Plant was the subject of the analysis. A review of plant history and its product is presented along with an analysis of manufacturing operations, includingmore » material and production flow, plant layout, machining and assembly processes, tooling, supporting facilities, inspection, service and repair. Four levels of product change intensity showing the impact on manufacturing methods and cost is also presented.« less

  6. A critical examination of stresses in an elastic single lap joint

    NASA Technical Reports Server (NTRS)

    Cooper, P. A.; Sawyer, J. W.

    1979-01-01

    The results of an approximate nonlinear finite-element analysis of a single lap joint are presented and compared with the results of a linear finite-element analysis, and the geometric nonlinear effects caused by the load-path eccentricity on the adhesive stress distributions are determined. The results from finite-element, Goland-Reissner, and photoelastic analyses show that for a single lap joint the effect of the geometric nonlinear behavior of the joint has a sizable effect on the stresses in the adhesive. The Goland-Reissner analysis is sufficiently accurate in the prediction of stresses along the midsurface of the adhesive bond to be used for qualitative evaluation of the influence of geometric or material parametric variations. Detailed stress distributions in both the adherend and adhesive obtained from the finite-element analysis are presented to provide a basis for comparison with other solution techniques.

  7. Evaluation of Diesel Engine Performance with Intake and Exhaust System Throttling : Volume 2. Appendix 1.

    DOT National Transportation Integrated Search

    1975-11-01

    The appendix to the preceding volume presents the data for the subject diesel engine noise study, including an engine sound power level analysis and sound spectrums showing the effect of intake and exhaust restrictions.

  8. Children's TV Ad Content: 1974

    ERIC Educational Resources Information Center

    Doolittle, John; Pepper, Robert

    1975-01-01

    An analysis of commercials on children's television programs shows that, with the advent of guidelines, some changes have been made, particularly in relation to vitamins, minerals, foods, and toys. Presentation techniques however contain increasing sex stereotyping and decreased presence of racial minorities. (LS)

  9. Three-Dimensional Orthogonal Co-ordinates

    ERIC Educational Resources Information Center

    Astin, J.

    1974-01-01

    A systematic approach to general orthogonal co-ordinates, suitable for use near the end of a beginning vector analysis course, is presented. It introduces students to tensor quantities and shows how equations and quantities needed in classical problems can be determined. (Author/LS)

  10. An Analysis of the Effects of Wing Aspect Ratio and Tail Location on Static Longitudinal Stability Below the Mach Number of Lift Divergence

    NASA Technical Reports Server (NTRS)

    Axelson, John A.; Crown, J. Conrad

    1948-01-01

    An analysis is presented of the influence of wing aspect ratio and tail location on the effects of compressibility upon static longitudinal stability. The investigation showed that the use of reduced wing aspect ratios or short tail lengths leads to serious reductions in high-speed stability and the possibility of high-speed instability.

  11. Ambulatory electronic medical record payback analysis 7 years after implementation in a tertiary care county medical system.

    PubMed

    Kaelber, David C; Miller, Vince; Fisher, Nancy; Schlesinger, Jim; Norris, Greg

    2007-10-11

    Electronic medical records (EMRs) are gaining increasing prominence in healthcare, however still have low market penetration. EMR implementation cost is a primary perceived barrier. Here we present a payback analysis on an outpatient EMR implementation, showing capital expense recovery (net of operating costs) at 6 years and now generating $6 million yearly in direct savings for our healthcare system.

  12. Newly Built Undergraduate Schools Should Place Great Emphasis on Connotation Construction and Quality Promotion: An Analysis Based on the Qualification Evaluation Results for 41 Undergraduate Schools

    ERIC Educational Resources Information Center

    Binglin, Zhong

    2016-01-01

    The article presents a quantitative analysis of the evaluation results for 41 newly built undergraduate schools that submitted to the qualification evaluation of undergraduate work by Ministry of Education in 2013. It shows that newly built undergraduate schools should place great emphasis on connotation construction and quality promotion and on…

  13. Direct Analysis of Low-Volatile Molecular Marker Extract from Airborne Particulate Matter Using Sensitivity Correction Method

    PubMed Central

    Irei, Satoshi

    2016-01-01

    Molecular marker analysis of environmental samples often requires time consuming preseparation steps. Here, analysis of low-volatile nonpolar molecular markers (5-6 ring polycyclic aromatic hydrocarbons or PAHs, hopanoids, and n-alkanes) without the preseparation procedure is presented. Analysis of artificial sample extracts was directly conducted by gas chromatography-mass spectrometry (GC-MS). After every sample injection, a standard mixture was also analyzed to make a correction on the variation of instrumental sensitivity caused by the unfavorable matrix contained in the extract. The method was further validated for the PAHs using the NIST standard reference materials (SRMs) and then applied to airborne particulate matter samples. Tests with the SRMs showed that overall our methodology was validated with the uncertainty of ~30%. The measurement results of airborne particulate matter (PM) filter samples showed a strong correlation between the PAHs, implying the contributions from the same emission source. Analysis of size-segregated PM filter samples showed that their size distributions were found to be in the PM smaller than 0.4 μm aerodynamic diameter. The observations were consistent with our expectation of their possible sources. Thus, the method was found to be useful for molecular marker studies. PMID:27127511

  14. Insertion Mutation of the Form I cbbL Gene Encoding Ribulose Bisphosphate Carboxylase/Oxygenase (RuBisCO) in Thiobacillus neapolitanus Results in Expression of Form II RuBisCO, Loss of Carboxysomes, and an Increased CO2 Requirement for Growth

    PubMed Central

    Baker, Stefanie H.; Jin, Songmu; Aldrich, Henry C.; Howard, Gary T.; Shively, Jessup M.

    1998-01-01

    It has been previously established that Thiobacillus neapolitanus fixes CO2 by using a form I ribulose bisphosphate carboxylase/oxygenase (RuBisCO), that much of the enzyme is sequestered into carboxysomes, and that the genes for the enzyme, cbbL and cbbS, are part of a putative carboxysome operon. In the present study, cbbL and cbbS were cloned and sequenced. Analysis of RNA showed that cbbL and cbbS are cotranscribed on a message approximately 2,000 nucleotides in size. The insertion of a kanamycin resistance cartridge into cbbL resulted in a premature termination of transcription; a polar mutant was generated. The mutant is able to fix CO2, but requires a CO2 supplement for growth. Separation of cellular proteins from both the wild type and the mutant on sucrose gradients and subsequent analysis of the RuBisCO activity in the collected fractions showed that the mutant assimilates CO2 by using a form II RuBisCO. This was confirmed by immunoblot analysis using antibodies raised against form I and form II RuBisCOs. The mutant does not possess carboxysomes. Smaller, empty inclusions are present, but biochemical analysis indicates that if they are carboxysome related, they are not functional, i.e., do not contain RuBisCO. Northern analysis showed that some of the shell components of the carboxysome are produced, which may explain the presence of these inclusions in the mutant. PMID:9696760

  15. A meta-analysis of the effects of β-adrenergic blockers in chronic heart failure.

    PubMed

    Zhang, Xiaojian; Shen, Chengwu; Zhai, Shujun; Liu, Yukun; Yue, Wen-Wei; Han, Li

    2016-10-01

    Adrenergic β-blockers are drugs that bind to, but do not activate β-adrenergic receptors. Instead they block the actions of β-adrenergic agonists and are used for the treatment of various diseases such as cardiac arrhythmias, angina pectoris, myocardial infarction, hypertension, headache, migraines, stress, anxiety, prostate cancer, and heart failure. Several meta-analysis studies have shown that β-blockers improve the heart function and reduce the risks of cardiovascular events, rate of mortality, and sudden death through chronic heart failure (CHF) of patients. The present study identified results from recent meta-analyses of β-adrenergic blockers and their usefulness in CHF. Databases including Medline/Embase/Cochrane Central Register of Controlled Trials (CENTRAL), and PubMed were searched for the periods May, 1985 to March, 2011 and June, 2013 to August, 2015, and a number of studies identified. Results of those studies showed that use of β-blockers was associated with decreased sudden cardiac death in patients with heart failure. However, contradictory results have also been reported. The present meta-analysis aimed to determine the efficacy of β-blockers on mortality and morbidity in patients with heart failure. The results showed that mortality was significantly reduced by β-blocker treatment prior to the surgery of heart failure patients. The results from the meta-analysis studies showed that β-blocker treatment in heart failure patients correlated with a significant decrease in long-term mortality, even in patients that meet one or more exclusion criteria of the MERIT-HF study. In summary, the findings of the current meta-analysis revealed beneficial effects different β-blockers have on patients with heart failure or related heart disease.

  16. A meta-analysis of the effects of β-adrenergic blockers in chronic heart failure

    PubMed Central

    Zhang, Xiaojian; Shen, Chengwu; Zhai, Shujun; Liu, Yukun; Yue, Wen-Wei; Han, Li

    2016-01-01

    Adrenergic β-blockers are drugs that bind to, but do not activate β-adrenergic receptors. Instead they block the actions of β-adrenergic agonists and are used for the treatment of various diseases such as cardiac arrhythmias, angina pectoris, myocardial infarction, hypertension, headache, migraines, stress, anxiety, prostate cancer, and heart failure. Several meta-analysis studies have shown that β-blockers improve the heart function and reduce the risks of cardiovascular events, rate of mortality, and sudden death through chronic heart failure (CHF) of patients. The present study identified results from recent meta-analyses of β-adrenergic blockers and their usefulness in CHF. Databases including Medline/Embase/Cochrane Central Register of Controlled Trials (CENTRAL), and PubMed were searched for the periods May, 1985 to March, 2011 and June, 2013 to August, 2015, and a number of studies identified. Results of those studies showed that use of β-blockers was associated with decreased sudden cardiac death in patients with heart failure. However, contradictory results have also been reported. The present meta-analysis aimed to determine the efficacy of β-blockers on mortality and morbidity in patients with heart failure. The results showed that mortality was significantly reduced by β-blocker treatment prior to the surgery of heart failure patients. The results from the meta-analysis studies showed that β-blocker treatment in heart failure patients correlated with a significant decrease in long-term mortality, even in patients that meet one or more exclusion criteria of the MERIT-HF study. In summary, the findings of the current meta-analysis revealed beneficial effects different β-blockers have on patients with heart failure or related heart disease. PMID:27703506

  17. Passive Fully Polarimetric W-Band Millimeter-Wave Imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bernacki, Bruce E.; Kelly, James F.; Sheen, David M.

    2012-04-01

    We present the theory, design, and experimental results obtained from a scanning passive W-band fully polarimetric imager. Passive millimeter-wave imaging offers persistent day/nighttime imaging and the ability to penetrate dust, clouds and other obscurants, including clothing and dry soil. The single-pixel scanning imager includes both far-field and near-field fore-optics for investigation of polarization phenomena. Using both fore-optics, a variety of scenes including natural and man-made objects was imaged and these results are presented showing the utility of polarimetric imaging for anomaly detection. Analysis includes conventional Stokes-parameter based approaches as well as multivariate image analysis methods.

  18. Numerical analysis for the fractional diffusion and fractional Buckmaster equation by the two-step Laplace Adam-Bashforth method

    NASA Astrophysics Data System (ADS)

    Jain, Sonal

    2018-01-01

    In this paper, we aim to use the alternative numerical scheme given by Gnitchogna and Atangana for solving partial differential equations with integer and non-integer differential operators. We applied this method to fractional diffusion model and fractional Buckmaster models with non-local fading memory. The method yields a powerful numerical algorithm for fractional order derivative to implement. Also we present in detail the stability analysis of the numerical method for solving the diffusion equation. This proof shows that this method is very stable and also converges very quickly to exact solution and finally some numerical simulation is presented.

  19. Speckle correlation method used to measure object's in-plane velocity.

    PubMed

    Smíd, Petr; Horváth, Pavel; Hrabovský, Miroslav

    2007-06-20

    We present a measurement of an object's in-plane velocity in one direction by the use of the speckle correlation method. Numerical correlations of speckle patterns recorded periodically during motion of the object under investigation give information used to evaluate the object's in-plane velocity. The proposed optical setup uses a detection plane in the image field and enables one to detect the object's velocity within the interval (10-150) microm x s(-1). Simulation analysis shows a way of controlling the measuring range. The presented theory, simulation analysis, and setup are verified through an experiment of measurement of the velocity profile of an object.

  20. Version 2.0 AERONET Dust Aerosol properties, Constraints and Application to Asian Dust Observations

    NASA Technical Reports Server (NTRS)

    Holben, Brent; Eck, Tom; Holben, Brent; Eck, Tom; Siniuk, Aliaksander; Huangand, Jianping; Zang, Wu

    2007-01-01

    In November 2006, AERONET released Version 2 of the Dubovik and King sky radiance and optical depth inversion. Reanalysis of the entire AERONET database revealed marked differences in aerosol properties in arid and semi arid regions with dust dominated aerosols. The change will be illustrated through sensitivity analysis and examples from the UAE2 (United Arab Emirates Unified Aerosol Experiment) field campaign. Properties of dust dominated aerosols will be presented from regional AERONET sites in China showing variations in dust aerosol properties. The constraints and limitations of the AERONET inversion will be presented that will facilitate analysis by the user community of these data.

  1. Dielectric Spectroscopy Analysis of Aged EVOH films with Application to Deterioration of Food Packaging Materials

    NASA Astrophysics Data System (ADS)

    Hoeller, Timothy

    2007-06-01

    Samples of EVOH films from compositions of 29 - 44 mol% ethylene content were exposed to thermal aging with and without light exposure. The results of Dielectric Spectroscopy on select samples showed Cole-Cole plots of skewed dielectric constant indicating multiple distributions of dipole relaxation times. The onset for decreases in dielectric response occurs earlier in samples exposed to elevated temperature under light exposure. Lower permittivity is exhibited in samples of higher ethylene content. Results from heat exposed samples are presented. Colorimetric analysis indicates only a slight film yellowing in one case. Raman spectroscopy on untreated films discerns changes in the C-C-O stretch associated with the alcohol. The effects of aging on microstructure may cause hindrance of molecular motion from moisture desorption. Slight material degradation occurs from film hardening presumably due to crosslinking. An electrical circuit model of the conduction processes associated with the EVOH films is presented. Dielectric analysis shows promise for monitoring material changes related to deterioration. We are also using these methods to understand Fluorescence Imaging which has been recently released for paper and plastic materials analysis. Future work may include refinement of these techniques for identification of changes in material properties correlated to packaging material barrier resistance.

  2. Detection And Identification Of Inflammatory Bowel Disease Electronic Nose

    NASA Astrophysics Data System (ADS)

    Covington, J. A.; Ouaret, N.; Gardner, J. W.; Nwokolo, C.; Bardhan, K. D.; Arasaradnam, R. P.

    2011-11-01

    Inflammatory bowel disease (IBD) is an inflammation of the lining of the human bowel and a major health issue in Europe. IBD carries with it significant morbidity from toxic treatment, surgery and a risk of developing bowel cancer. Thus there is a need for early identification of the disease using non-invasive tests. Present diagnostic techniques are based around invasive tests (i.e. endoscopy) and laboratory culture; the latter is limited as only 50% of the gut bacteria can be identified. Here we explore the use of an e-nose as a tool to detect and identify two IBDs (i.e. Crohn's disease (CD) & Ulcerative Colitis (UC)) based on headspace analysis from urine samples. We believe that the gut bacterial flora is altered by disease (due to fermentation) that in-turn modulates the gas composition within urine samples. 24 samples (9 CD, 6 UC, 9 controls) were analysed with an in-house e-nose and an Owlstone IMS instrument. Data analysis was performed using linear discriminant analysis (LDA and principal components analysis (PCA). Using the e-nose, LDA separates both disease groups and control, whilst PCA shows a small overlap of classes. The IMS data are more complex but shows some disease/control separation. We are presently collecting further samples for a larger study using more advanced data processing methods.

  3. Synthesis, characterizations and anti-bacterial activities of pure and Ag doped CdO nanoparticles by chemical precipitation method

    NASA Astrophysics Data System (ADS)

    Sivakumar, S.; Venkatesan, A.; Soundhirarajan, P.; Khatiwada, Chandra Prasad

    2015-02-01

    In the present study, synthesized pure and Ag (1%, 2%, and 3%) doped Cadmium Oxide (CdO) nanoparticles by chemical precipitation method. Then, the synthesized products were characterized by thermo gravimetric-differential thermal analysis (TG-DTA), X-ray diffraction (XRD) analysis, Fourier transform infrared (FT-IR) spectroscopy, Ultra violet-Vis diffused reflectance spectroscopy (UV-Vis-DRS), Scanning electron microscopy (SEM), Energy dispersive X-rays (EDX) spectroscopy, and anti-bacterial activities, respectively. The transition temperatures and phase transitions of Cd(OH)2 to CdO at 400 °C was confirmed by TG-DTA analysis. The XRD patterns show the cubic shape and average particle sizes are 21, 40, 34, and 37 nm, respectively for pure and Ag doped samples. FT-IR study confirmed the presence of CdO and Ag at 677 and 459 cm-1, respectively. UV-Vis-DRS study shows the variation on direct and indirect band gaps. The surface morphologies and elemental analysis have been confirmed from SEM and with EDX. In addition, the synthesized products have been characterized by antibacterial activities against Gram-positive and negative bacteria. Further, the present investigation suggests that CdO nanoparticles have the great potential applications on various industrial and medical fields of research.

  4. The chemical composition of tertiary Indian coal ash and its combustion behaviour - a statistical approach: Part 2

    NASA Astrophysics Data System (ADS)

    Sharma, Arpita; Saikia, Ananya; Khare, Puja; Dutta, D. K.; Baruah, B. P.

    2014-08-01

    In Part 1 of the present investigation, 37 representative Eocene coal samples of Meghalaya, India were analyzed and their physico-chemical characteristics and the major oxides and minerals present in ash samples were studied for assessing the genesis of these coals. Various statistical tools were also applied to study their genesis. The datasets from Part 1 used in this investigation (Part 2) show the contribution of major oxides towards ash fusion temperatures (AFTs). The regression analysis of high temperature ash (HTA) composition and initial deformation temperature (IDT) show a definite increasing or decreasing trend, which has been used to determine the predictive indices for slagging, fouling, and abrasion propensities during combustion practices. The increase or decrease of IDT is influenced by the increase of Fe2O3, Al2O3, SiO2, and CaO, respectively. Detrital-authigenic index (DAI) calculated from the ash composition and its relation with AFT indicates Sialoferric nature of these coals. The correlation analysis, Principal Component Analysis (PCA), and Hierarchical Cluster Analysis (HCA) were used to study the possible fouling, slagging, and abrasion potentials in boilers during the coal combustion processes. A positive relationship between slagging and heating values of the coal has been found in this study.

  5. Physical and chemical properties of aerosols at a coastal site Paposo (Chile) during VOCALS campaign

    NASA Astrophysics Data System (ADS)

    Cordova, A. M.; Chand, D.; Wood, R.; Wallace, D.; Hegg, D. A.; Shaw, G. E.; Krejci, R.; Fochesatto, G. J.; Gallardo, L.

    2009-12-01

    One of the primary goals of the VOCALS (VAMOS* Ocean-Cloud-Atmosphere-Land Study) Regional Experiment (REx) and associated modeling program is an improved understanding of aerosol indirect effects over the southeast Pacific (SEP). Details on the program are available online at www.eol.ucar.edu/projects/vocals/. To this end, detailed aerosol physical and chemical measurements were made during REx at a coastal land site at Paposo (25o 0.4' S, 70o 27.011' W, 690 masl) in northern Chile, a site ideally positioned for studying continental aerosol sources advecting over the SEP. We present initial analysis of data from Paposo. Detailed measurements of aerosol properties were made from mid October to mid November 2008. Observations from optical particle counters (OPC), nephelometers, aethalometer, scanning mobility particle sizer (SMPS) and the chemical analysis of the submicron aerosols samples collected on teflon filters are being used in this study. Large variations in aerosols parameters were observed which corresponded with changes in meteorology, as determined using trajectory analysis. Ion Chromatograph (IC) analysis of submicron aerosol samples shows that about 41% of submicron mass is sulfate. The light scattering coefficient shows a strong non-linear correlation with aerosol size observed using an OPC. Detailed results will be presented in the AGU meeting.

  6. Primary analysis for clinical efficacy of immunotherapy in patients with pancreatic cancer.

    PubMed

    Chen, Linghua; Zhang, Xiaoyan

    2016-02-01

    Immunotherapy is an important treatment for pancreatic cancer (PC) patients. To evaluate the therapeutic efficacy of immunotherapy in the treatment of PC, we performed a systemic review and meta-analysis of the relevant published clinical trials, collectively referred to as DC, DC-CIK, LAK, NK and GM-CSF secreting PC cell lines.  A total of 413 patients in 11 eligible trials with PC were selected for the present meta-analysis. The estimated pooled overall survival showed a significant improvement for PC patients who received immunotherapy compared with nonimmunotherapy. The lymphocyte subsets, immune cytokine levels and serum cancer markers in the peripheral blood of PC patients were significantly improved after immunotherapy. The results showed that immunotherapy can improve the efficacy of the treatment of PC patients.

  7. Brightness-preserving fuzzy contrast enhancement scheme for the detection and classification of diabetic retinopathy disease.

    PubMed

    Datta, Niladri Sekhar; Dutta, Himadri Sekhar; Majumder, Koushik

    2016-01-01

    The contrast enhancement of retinal image plays a vital role for the detection of microaneurysms (MAs), which are an early sign of diabetic retinopathy disease. A retinal image contrast enhancement method has been presented to improve the MA detection technique. The success rate on low-contrast noisy retinal image analysis shows the importance of the proposed method. Overall, 587 retinal input images are tested for performance analysis. The average sensitivity and specificity are obtained as 95.94% and 99.21%, respectively. The area under curve is found as 0.932 for the receiver operating characteristics analysis. The classifications of diabetic retinopathy disease are also performed here. The experimental results show that the overall MA detection method performs better than the current state-of-the-art MA detection algorithms.

  8. Conversation analysis as a method for investigating interaction in care home environments.

    PubMed

    Chatwin, John

    2014-11-01

    This article gives an outline of how the socio-linguistic approach of conversation analysis can be applied to the analysis of carer-patient interaction in care homes. A single case study from a routine encounter in a residential care home is presented. This is used to show how the conversation analysis method works, the kinds of interactional and communication features it can expose, and what specific contribution this kind of micro-interactional approach may make to improving quality of care in these environments. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

  9. Study of Selected Composites Copper Concentrate-Plastic Waste Using Thermal Analysis

    NASA Astrophysics Data System (ADS)

    Szyszka, Danuta

    2017-12-01

    The paper presents thermal analysis of selected composites (copper concentrate, plastic waste) in two stages. The first stage consisted in thermogravimetric analysis and differential thermal analysis on the applied plastic waste and copper concentrate, and subsequently, a comparative study has been carried out on products obtained, constituting composites of those materials. As a result of analyses, it was found that up to ca. 400 °C composites show high thermal stability, whereas above that temperature, a thermal decomposition of the composite occurs, resulting in emissions of organic compounds, i.e. hydrocarbon compounds and organic oxygenate derivatives.

  10. Projection-based motion estimation for cardiac functional analysis with high temporal resolution: a proof-of-concept study with digital phantom experiment

    NASA Astrophysics Data System (ADS)

    Suzuki, Yuki; Fung, George S. K.; Shen, Zeyang; Otake, Yoshito; Lee, Okkyun; Ciuffo, Luisa; Ashikaga, Hiroshi; Sato, Yoshinobu; Taguchi, Katsuyuki

    2017-03-01

    Cardiac motion (or functional) analysis has shown promise not only for non-invasive diagnosis of cardiovascular diseases but also for prediction of cardiac future events. Current imaging modalities has limitations that could degrade the accuracy of the analysis indices. In this paper, we present a projection-based motion estimation method for x-ray CT that estimates cardiac motion with high spatio-temporal resolution using projection data and a reference 3D volume image. The experiment using a synthesized digital phantom showed promising results for motion analysis.

  11. Semiconductor Quantum Electron Wave Transport, Diffraction, and Interference: Analysis, Device, and Measurement.

    NASA Astrophysics Data System (ADS)

    Henderson, Gregory Newell

    Semiconductor device dimensions are rapidly approaching a fundamental limit where drift-diffusion equations and the depletion approximation are no longer valid. In this regime, quantum effects can dominate device response. To increase further device density and speed, new devices must be designed that use these phenomena to positive advantage. In addition, quantum effects provide opportunities for a new class of devices which can perform functions previously unattainable with "conventional" semiconductor devices. This thesis has described research in the analysis of electron wave effects in semiconductors and the development of methods for the design, fabrication, and characterization of quantum devices based on these effects. First, an exact set of quantitative analogies are presented which allow the use of well understood optical design and analysis tools for the development of electron wave semiconductor devices. Motivated by these analogies, methods are presented for modeling electron wave grating diffraction using both an exact rigorous coupled-wave analysis and approximate analyses which are useful for grating design. Example electron wave grating switch and multiplexer designs are presented. In analogy to thin-film optics, the design and analysis of electron wave Fabry-Perot interference filters are also discussed. An innovative technique has been developed for testing these (and other) electron wave structures using Ballistic Electron Emission Microscopy (BEEM). This technique uses a liquid-helium temperature scanning tunneling microscope (STM) to perform spectroscopy of the electron transmittance as a function of electron energy. Experimental results show that BEEM can resolve even weak quantum effects, such as the reflectivity of a single interface between materials. Finally, methods are discussed for incorporating asymmetric electron wave Fabry-Perot filters into optoelectronic devices. Theoretical and experimental results show that such structures could be the basis for a new type of electrically pumped mid - to far-infrared semiconductor laser.

  12. [Quantitative surface analysis of Pt-Co, Cu-Au and Cu-Ag alloy films by XPS and AES].

    PubMed

    Li, Lian-Zhong; Zhuo, Shang-Jun; Shen, Ru-Xiang; Qian, Rong; Gao, Jie

    2013-11-01

    In order to improve the quantitative analysis accuracy of AES, We associated XPS with AES and studied the method to reduce the error of AES quantitative analysis, selected Pt-Co, Cu-Au and Cu-Ag binary alloy thin-films as the samples, used XPS to correct AES quantitative analysis results by changing the auger sensitivity factors to make their quantitative analysis results more similar. Then we verified the accuracy of the quantitative analysis of AES when using the revised sensitivity factors by other samples with different composition ratio, and the results showed that the corrected relative sensitivity factors can reduce the error in quantitative analysis of AES to less than 10%. Peak defining is difficult in the form of the integral spectrum of AES analysis since choosing the starting point and ending point when determining the characteristic auger peak intensity area with great uncertainty, and to make analysis easier, we also processed data in the form of the differential spectrum, made quantitative analysis on the basis of peak to peak height instead of peak area, corrected the relative sensitivity factors, and verified the accuracy of quantitative analysis by the other samples with different composition ratio. The result showed that the analytical error in quantitative analysis of AES reduced to less than 9%. It showed that the accuracy of AES quantitative analysis can be highly improved by the way of associating XPS with AES to correct the auger sensitivity factors since the matrix effects are taken into account. Good consistency was presented, proving the feasibility of this method.

  13. Analysis and comparison of methods for the preparation of domestic hot water from district heating system, selected renewable and non-renewable sources in low-energy buildings

    NASA Astrophysics Data System (ADS)

    Knapik, Maciej

    2018-02-01

    The article presents an economic analysis and comparison of selected (district heating, natural gas, heat pump with renewable energy sources) methods for the preparation of domestic hot water in a building with low energy demand. In buildings of this type increased demand of energy for domestic hot water preparation in relation to the total energy demand can be observed. As a result, the proposed solutions allow to further lower energy demand by using the renewable energy sources. This article presents the results of numerical analysis and calculations performed mainly in MATLAB software, based on typical meteorological years. The results showed that system with heat pump and renewable energy sources Is comparable with district heating system.

  14. Ice Growth Measurements from Image Data to Support Ice Crystal and Mixed-Phase Accretion Testing

    NASA Technical Reports Server (NTRS)

    Struk, Peter M.; Lynch, Christopher J.

    2012-01-01

    This paper describes the imaging techniques as well as the analysis methods used to measure the ice thickness and growth rate in support of ice-crystal icing tests performed at the National Research Council of Canada (NRC) Research Altitude Test Facility (RATFac). A detailed description of the camera setup, which involves both still and video cameras, as well as the analysis methods using the NASA Spotlight software, are presented. Two cases, one from two different test entries, showing significant ice growth are analyzed in detail describing the ice thickness and growth rate which is generally linear. Estimates of the bias uncertainty are presented for all measurements. Finally some of the challenges related to the imaging and analysis methods are discussed as well as methods used to overcome them.

  15. Ice Growth Measurements from Image Data to Support Ice-Crystal and Mixed-Phase Accretion Testing

    NASA Technical Reports Server (NTRS)

    Struk, Peter, M; Lynch, Christopher, J.

    2012-01-01

    This paper describes the imaging techniques as well as the analysis methods used to measure the ice thickness and growth rate in support of ice-crystal icing tests performed at the National Research Council of Canada (NRC) Research Altitude Test Facility (RATFac). A detailed description of the camera setup, which involves both still and video cameras, as well as the analysis methods using the NASA Spotlight software, are presented. Two cases, one from two different test entries, showing significant ice growth are analyzed in detail describing the ice thickness and growth rate which is generally linear. Estimates of the bias uncertainty are presented for all measurements. Finally some of the challenges related to the imaging and analysis methods are discussed as well as methods used to overcome them.

  16. Total hydrocarbon content (THC) testing in liquid oxygen (LOX) systems

    NASA Astrophysics Data System (ADS)

    Meneghelli, B. J.; Obregon, R. E.; Ross, H. R.; Hebert, B. J.; Sass, J. P.; Dirschka, G. E.

    2015-12-01

    The measured Total Hydrocarbon Content (THC) levels in liquid oxygen (LOX) systems at Stennis Space Center (SSC) have shown wide variations. Examples of these variations include the following: 1) differences between vendor-supplied THC values and those obtained using standard SSC analysis procedures; and 2) increasing THC values over time at an active SSC test stand in both storage and run vessels. A detailed analysis of LOX sampling techniques, analytical instrumentation, and sampling procedures will be presented. Additional data obtained on LOX system operations and LOX delivery trailer THC values during the past 12-24 months will also be discussed. Field test results showing THC levels and the distribution of the THC's in the test stand run tank, modified for THC analysis via dip tubes, will be presented.

  17. Simultaneous grouping and ranking with combination of SOM and TOPSIS for selection of preferable analytical procedure for furan determination in food.

    PubMed

    Jędrkiewicz, Renata; Tsakovski, Stefan; Lavenu, Aurore; Namieśnik, Jacek; Tobiszewski, Marek

    2018-02-01

    Novel methodology for grouping and ranking with application of self-organizing maps and multicriteria decision analysis is presented. The dataset consists of 22 objects that are analytical procedures applied to furan determination in food samples. They are described by 10 variables, referred to their analytical performance, environmental and economic aspects. Multivariate statistics analysis allows to limit the amount of input data for ranking analysis. Assessment results show that the most beneficial procedures are based on microextraction techniques with GC-MS final determination. It is presented how the information obtained from both tools complement each other. The applicability of combination of grouping and ranking is also discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

  18. Transonic CFD applications at Boeing

    NASA Technical Reports Server (NTRS)

    Tinoco, E. N.

    1989-01-01

    The use of computational methods for three dimensional transonic flow design and analysis at the Boeing Company is presented. A range of computational tools consisting of production tools for every day use by project engineers, expert user tools for special applications by computational researchers, and an emerging tool which may see considerable use in the near future are described. These methods include full potential and Euler solvers, some coupled to three dimensional boundary layer analysis methods, for transonic flow analysis about nacelle, wing-body, wing-body-strut-nacelle, and complete aircraft configurations. As the examples presented show, such a toolbox of codes is necessary for the variety of applications typical of an industrial environment. Such a toolbox of codes makes possible aerodynamic advances not previously achievable in a timely manner, if at all.

  19. Core-Shell Columns in High-Performance Liquid Chromatography: Food Analysis Applications

    PubMed Central

    Preti, Raffaella

    2016-01-01

    The increased separation efficiency provided by the new technology of column packed with core-shell particles in high-performance liquid chromatography (HPLC) has resulted in their widespread diffusion in several analytical fields: from pharmaceutical, biological, environmental, and toxicological. The present paper presents their most recent applications in food analysis. Their use has proved to be particularly advantageous for the determination of compounds at trace levels or when a large amount of samples must be analyzed fast using reliable and solvent-saving apparatus. The literature hereby described shows how the outstanding performances provided by core-shell particles column on a traditional HPLC instruments are comparable to those obtained with a costly UHPLC instrumentation, making this novel column a promising key tool in food analysis. PMID:27143972

  20. Total Hydrocarbon Content (THC) Testing in Liquid Oxygen (LOX)

    NASA Technical Reports Server (NTRS)

    Meneghelli, B. J.; Obregon, R. E.; Ross, H. R.; Hebert, B. J.; Sass, J. P.; Dirschka, G. E.

    2016-01-01

    The measured Total Hydrocarbon Content (THC) levels in liquid oxygen (LOX) systems at Stennis Space Center (SSC) have shown wide variations. Examples of these variations include the following: 1) differences between vendor-supplied THC values and those obtained using standard SSC analysis procedures; and 2) increasing THC values over time at an active SSC test stand in both storage and run vessels. A detailed analysis of LOX sampling techniques, analytical instrumentation, and sampling procedures will be presented. Additional data obtained on LOX system operations and LOX delivery trailer THC values during the past 12-24 months will also be discussed. Field test results showing THC levels and the distribution of the THC's in the test stand run tank, modified for THC analysis via dip tubes, will be presented.

  1. Propagation Constant of a Rectangular Waveguides Completely Full of Ferrite Magnetized Longitudinally

    NASA Astrophysics Data System (ADS)

    Sakli, Hedi; Benzina, Hafedh; Aguili, Taoufik; Tao, Jun Wu

    2009-08-01

    This paper is an analysis of rectangular waveguide completely full of ferrite magnetized longitudinally. The analysis is based on the formulation of the transverse operator method (TOM), followed by the application of the Galerkin method. We obtain an eigenvalue equation system. The propagation constant of some homogenous and anisotropic waveguide structures with ferrite has been obtained. The results presented here show that the transverse operator formulation is not only an elegant theoretical form, but also a powerful and efficient analysis method, it is useful to solve a number of the propagation problems in electromagnetic. One advantage of this method is that it presents a fast convergence. Numerical examples are given for different cases and compared with the published results. A good agreement is obtained.

  2. Isogeometric analysis of free-form Timoshenko curved beams including the nonlinear effects of large deformations

    NASA Astrophysics Data System (ADS)

    Hosseini, Seyed Farhad; Hashemian, Ali; Moetakef-Imani, Behnam; Hadidimoud, Saied

    2018-03-01

    In the present paper, the isogeometric analysis (IGA) of free-form planar curved beams is formulated based on the nonlinear Timoshenko beam theory to investigate the large deformation of beams with variable curvature. Based on the isoparametric concept, the shape functions of the field variables (displacement and rotation) in a finite element analysis are considered to be the same as the non-uniform rational basis spline (NURBS) basis functions defining the geometry. The validity of the presented formulation is tested in five case studies covering a wide range of engineering curved structures including from straight and constant curvature to variable curvature beams. The nonlinear deformation results obtained by the presented method are compared to well-established benchmark examples and also compared to the results of linear and nonlinear finite element analyses. As the nonlinear load-deflection behavior of Timoshenko beams is the main topic of this article, the results strongly show the applicability of the IGA method to the large deformation analysis of free-form curved beams. Finally, it is interesting to notice that, until very recently, the large deformations analysis of free-form Timoshenko curved beams has not been considered in IGA by researchers.

  3. Bayesian data analysis tools for atomic physics

    NASA Astrophysics Data System (ADS)

    Trassinelli, Martino

    2017-10-01

    We present an introduction to some concepts of Bayesian data analysis in the context of atomic physics. Starting from basic rules of probability, we present the Bayes' theorem and its applications. In particular we discuss about how to calculate simple and joint probability distributions and the Bayesian evidence, a model dependent quantity that allows to assign probabilities to different hypotheses from the analysis of a same data set. To give some practical examples, these methods are applied to two concrete cases. In the first example, the presence or not of a satellite line in an atomic spectrum is investigated. In the second example, we determine the most probable model among a set of possible profiles from the analysis of a statistically poor spectrum. We show also how to calculate the probability distribution of the main spectral component without having to determine uniquely the spectrum modeling. For these two studies, we implement the program Nested_fit to calculate the different probability distributions and other related quantities. Nested_fit is a Fortran90/Python code developed during the last years for analysis of atomic spectra. As indicated by the name, it is based on the nested algorithm, which is presented in details together with the program itself.

  4. Enantiomeric and Isotopic Analysis of Sugar Derivatives in Carbonaceous Meteorites

    NASA Technical Reports Server (NTRS)

    Cooper, George; Asiyo, Cynthia; Turk, Kendra; DeVincenzi, Donald (Technical Monitor)

    2002-01-01

    Several classes of organic compounds are found in carbonaceous meteorites including amino acids, carboxylic acids, hydroxy acids, purines, and pyrimidines. Such compounds are thought to have been delivered to the early Earth in asteroids and comets and may have played a role in the origin of life. Likewise, sugar derivatives are critical to all known lifeforms. Recent analyses of the Murchison and Murray carbonaceous meteorites revealed a diverse suite of such derivatives, i.e., sugar alcohols, and sugar acids. This presentation will focus primarily on the analysis of individual sugar acids - their enantiomeric and isotopic composition. Analysis of these compounds may reveal the nature of past (or present) meteoritic sugars themselves. For example, if parent sugars decomposed (by well-known mechanisms) to give the present acids, were their enantiomeric ratios preserved? Combined with other evidence, the enantiomeric composition of such compounds as glyceric acid and (especially) rare acids may help to answer such questions. C-13 and D isotope analysis of meteoritic sugar alcohols (glycerol, threitol, ribitol, etc.) as a group revealed that they were indigenous to the meteorite. Preliminary C-13 analysis of glyceric acid shows that it is also extraterrestrial.

  5. Multivariate analysis of prognostic factors in synovial sarcoma.

    PubMed

    Koh, Kyoung Hwan; Cho, Eun Yoon; Kim, Dong Wook; Seo, Sung Wook

    2009-11-01

    Many studies have described the diversity of synovial sarcoma in terms of its biological characteristics and clinical features. Moreover, much effort has been expended on the identification of prognostic factors because of unpredictable behaviors of synovial sarcomas. However, with the exception of tumor size, published results have been inconsistent. We attempted to identify independent risk factors using survival analysis. Forty-one consecutive patients with synovial sarcoma were prospectively followed from January 1997 to March 2008. Overall and progression-free survival for age, sex, tumor size, tumor location, metastasis at presentation, histologic subtype, chemotherapy, radiation therapy, and resection margin were analyzed, and standard multivariate Cox proportional hazard regression analysis was used to evaluate potential prognostic factors. Tumor size (>5 cm), nonlimb-based tumors, metastasis at presentation, and a monophasic subtype were associated with poorer overall survival. Multivariate analysis showed metastasis at presentation and monophasic tumor subtype affected overall survival. For the progression-free survival, monophasic subtype was found to be only 1 prognostic factor. The study confirmed that histologic subtype is the single most important independent prognostic factors of synovial sarcoma regardless of tumor stage.

  6. Development and Analysis of New Integrated Energy Systems for Sustainable Buildings

    NASA Astrophysics Data System (ADS)

    Khalid, Farrukh

    Excessive consumption of fossil fuels in the residential sector and their associated negative environmental impacts bring a significant challenge to engineers within research and industrial communities throughout the world to develop more environmentally benign methods of meeting energy needs of residential sector in particular. This thesis addresses potential solutions for the issue of fossils fuel consumption in residential buildings. Three novel renewable energy based multigeneration systems are proposed for different types of residential buildings, and a comprehensive assessment of energetic and exergetic performances is given on the basis of total occupancy, energy load, and climate conditions. System 1 is a multigeneration system based on two renewable energy sources. It uses biomass and solar resources. The outputs of System 1 are electricity, space heating, cooling, and hot water. The energy and exergy efficiencies of System 1 are 91.0% and 34.9%, respectively. The results of the optimisation analysis show that the net present cost of System 1 is 2,700,496 and that the levelised cost of electricity is 0.117/kWh. System 2 is a multigeneration system, integrating three renewable energy based subsystems; wind turbine, concentrated solar collector, and Organic Rankine Cycle supplied by a ground source heat exchanger. The outputs of the System 2 are electricity, hot water, heating and cooling. The optimisation analysis shows that net present cost is 35,502 and levelised cost of electricity is 0.186/kWh. The energy and exergy efficiencies of System 2 are found to be 34.6% and 16.2%, respectively. System 3 is a multigeneration system, comprising two renewable energy subsystems-- geothermal and solar to supply power, cooling, heating, and hot water. The optimisation analysis shows that the net present cost of System 3 is 598,474, and levelised cost of electricity of 0.111/kWh. The energy and exergy efficiencies of System 3 are 20.2% and 19.2%, respectively, with outputs of electricity, hot water, cooling and space heating. A performance assessment for identical conditions indicates that System 3 offers the best performance, with the minimum net present cost of 26,001 and levelised cost of electricity of 0.136/kWh.

  7. Performance analysis of mini-propellers based on FlightGear

    NASA Astrophysics Data System (ADS)

    Vogeltanz, Tomáš

    2016-06-01

    This paper presents a performance analysis of three mini-propellers based on the FlightGear flight simulator. Although a basic propeller analysis has to be performed before the use of FlightGear, for a complex and more practical performance analysis, it is advantageous to use a propeller model in cooperation with a particular aircraft model. This approach may determine whether the propeller has sufficient quality in respect of aircraft requirements. In the first section, the software used for the analysis is illustrated. Then, the parameters of the analyzed mini-propellers and the tested UAV are described. Finally, the main section shows and discusses the results of the performance analysis of the mini-propellers.

  8. Analysis of Atmospheric Trace Constituents from High Resolution Infrared Balloon-Borne and Ground-Based Solar Absorption Spectra

    NASA Technical Reports Server (NTRS)

    Goldman, A.; Murcray, F. J.; Rinsland, C. P.; Blatherwick, R. D.; Murcray, F. H.; Murcray, D. G.

    1991-01-01

    Recent results and ongoing studies of high resolution solar absorption spectra will be presented. The analysis of these spectra is aimed at the identification and quantification of trace constituents important in atmospheric chemistry of the stratosphere and upper troposphere. Analysis of balloon-borne and ground-based spectra obtained at 0.0025/ cm covering the 700-2200/ cm interval will be presented. Results from ground-based 0.02/ cm solar spectra, from several locations such as Denver, South Pole, M. Loa, and New Zealand will also be shown. The 0.0025/ cm spectra show many new spectroscopic features. The analysis of these spectra, along with corresponding laboratory spectra, improves the spectral line parameters, and thus the accuracy of trace constituents quantification. The combination of the recent balloon flights, with earlier flights data since 1978 at 0.02/ cm resolution, provides trends analysis of several stratospheric trace species. Results for COF2, F22, SF6, and other species will be presented. Analysis of several ground-based solar spectra provides trends for HCl, HF and other species. The retrieval methods used for total column density and altitude distribution for both ground-based and balloon-borne spectra will be presented. These are extended for the analysis of the ground-based spectra to be obtained by the high resolution interferometers of the Network for Detection of Stratospheric Change (NDSC). Progress or the University of Denver studies for the NDSC will be presented. This will include intercomparison of solar spectra and trace gases retrievals obtained from simultaneous scans by the high resolution (0.0025/ cm) interferometers of BRUKER and BOMEM.

  9. Meta-analysis of haplotype-association studies: comparison of methods and empirical evaluation of the literature

    PubMed Central

    2011-01-01

    Background Meta-analysis is a popular methodology in several fields of medical research, including genetic association studies. However, the methods used for meta-analysis of association studies that report haplotypes have not been studied in detail. In this work, methods for performing meta-analysis of haplotype association studies are summarized, compared and presented in a unified framework along with an empirical evaluation of the literature. Results We present multivariate methods that use summary-based data as well as methods that use binary and count data in a generalized linear mixed model framework (logistic regression, multinomial regression and Poisson regression). The methods presented here avoid the inflation of the type I error rate that could be the result of the traditional approach of comparing a haplotype against the remaining ones, whereas, they can be fitted using standard software. Moreover, formal global tests are presented for assessing the statistical significance of the overall association. Although the methods presented here assume that the haplotypes are directly observed, they can be easily extended to allow for such an uncertainty by weighting the haplotypes by their probability. Conclusions An empirical evaluation of the published literature and a comparison against the meta-analyses that use single nucleotide polymorphisms, suggests that the studies reporting meta-analysis of haplotypes contain approximately half of the included studies and produce significant results twice more often. We show that this excess of statistically significant results, stems from the sub-optimal method of analysis used and, in approximately half of the cases, the statistical significance is refuted if the data are properly re-analyzed. Illustrative examples of code are given in Stata and it is anticipated that the methods developed in this work will be widely applied in the meta-analysis of haplotype association studies. PMID:21247440

  10. Caenorhabditis elegans syndecan (SDN-1) is required for normal egg laying and associates with the nervous system and the vulva.

    PubMed

    Minniti, Alicia N; Labarca, Mariana; Hurtado, Claudia; Brandan, Enrique

    2004-10-01

    In Caenorhabditis elegans, the identification of many enzymes involved in the synthesis and modification of glycosaminoglycans (GAGs), essential components of proteoglycans, has attained special attention in recent years. Mutations in all the genes that encode for GAG biosynthetic enzymes show defects in the development of the vulva, specifically in the invagination of the vulval epithelium. Mutants for certain heparan sulfate modifying enzymes present axonal and cellular guidance defects in specific neuronal classes. Although most of the enzymes involved in the biosynthesis and modification of heparan sulfate have been characterized in C. elegans, little is known regarding the core proteins to which these GAGs covalently bind in proteoglycans. A single syndecan homologue (sdn-1) has been identified in the C. elegans genome through sequence analysis. In the present study, we show that C. elegans synthesizes sulfated proteoglycans, seen as three distinct species in western blot analysis. In the sdn-1 (ok449) deletion mutant allele we observed the lack of one species, which corresponds to a 50 kDa product after heparitinase treatment. The expression of sdn-1 mRNA and sequencing revealed that sdn-1 (ok449) deletion mutants lack two glycosylation sites. Hence, the missing protein in the western blot analysis probably corresponds to SDN-1. In addition, we show that SDN-1 localizes to the C. elegans nerve ring, nerve cords and to the vulva. SDN-1 is found specifically phosphorylated in nerve ring neurons and in the vulva, in both wild-type worms and sdn-1 (ok449) deletion mutants. These mutants show a defective egg-laying phenotype. Our results show for the first time, the identification, localization and some functional aspects of syndecan in the nematode C. elegans.

  11. Industry 4.0 Concept Introduction into Construction SMEs

    NASA Astrophysics Data System (ADS)

    Nowotarski, Piotr; Paslawski, Jerzy

    2017-10-01

    The article presents a general idea of Industry 4.0 concept with the introduction presenting descriptions of the most important aspects in terms of production and construction industry development. The importance of the SME sector is stressed showing that this group of companies plays significant role in the European economy. The main objective of the article is to define and show possible research areas connected with the introduction of Industry 4.0 concept into SMEs with the main focus on the construction sector. For this purpose, an analysis was made, based on the most recent literature, to point out actual needs in the SMEs sector in terms of its evolution into 4.0 level. What is more, the analysis was performed based on the most popular articles published in journals available in Thomson Reuters Web of Science Core Collection database regarding Industry 4.0 concept in the last decade showing the actual change of interest in this filed, taking into account possibility of usage of this concept in the construction and production sector. Authors tried to describe current knowledge regarding Industry 4.0 introduction for SMEs. Performed analysis showed that there is a wide spectrum of disciplines that are affected by the Industry 4.0 that needs to be examined considering introduction into SMEs. Study also showed that multidiscipline approach was not investigated so far to create special rules, procedures and methods and know-how designed for introduction of main principles of Industry 4.0 in the SME sector. Authors came to the conclusions that there should be more stress put into research in this field especially taking into account the huge potential which lies in SME sector in terms of global economic strength.

  12. Factor Analysis of the Brazilian Version of UPPS Impulsive Behavior Scale

    PubMed Central

    Sediyama, Cristina Y. N.; Moura, Ricardo; Garcia, Marina S.; da Silva, Antonio G.; Soraggi, Carolina; Neves, Fernando S.; Albuquerque, Maicon R.; Whiteside, Setephen P.; Malloy-Diniz, Leandro F.

    2017-01-01

    Objective: To examine the internal consistency and factor structure of the Brazilian adaptation of the UPPS Impulsive Behavior Scale. Methods: UPPS is a self-report scale composed by 40 items assessing four factors of impulsivity: (a) urgency, (b) lack of premeditation; (c) lack of perseverance; (d) sensation seeking. In the present study 384 participants (278 women and 106 men), who were recruited from schools, universities, leisure centers and workplaces fulfilled the UPPS scale. An exploratory factor analysis was performed by using Varimax factor rotation and Kaiser Normalization, and we also conducted two confirmatory analyses to test the independency of the UPPS components found in previous analysis. Results: Results showed a decrease in mean UPPS total scores with age and this analysis showed that the youngest participants (below 30 years) scored significantly higher than the other groups over 30 years. No difference in gender was found. Cronbach’s alpha, results indicated satisfactory values for all subscales, with similar high values for the subscales and confirmatory factor analysis indexes also indicated a poor model fit. The results of two exploratory factor analysis were satisfactory. Conclusion: Our results showed that the Portuguese version has the same four-factor structure of the original and previous translations of the UPPS. PMID:28484414

  13. [The registry of home artificial nutrition and ambulatory of the Spanish Society of Parenteral and Enteral Nutrition; SWOT analysis].

    PubMed

    Wanden-Berghe, C; Pérez de la Cruz, A; Lobo Tamer, G; Calleja Fernández, A; Gómez Candela, C; Zugasti Murillo, A; Apezetxea Celaya, A; Torres Corts, A; Moreno Villarés, J M; de Luis, D; Penacho, Ma Á; Laborda, L; Burgos, R; Irles, J A; Cuerda Compes, C; Virgili Casas, Ma N; Martínez Olmos, M A; García Luna, P P

    2012-01-01

    To evidence by means of a SWOT-R analysis performed by an expert consensus the most worrying characteristics of the register on Home-based and Outpatient Artificial Nutrition. SWOT-R analysis with expert consensus. We requested the participation of the active members of the NADYA group within the last 5 years with the premise of structuring the SWOT-R based on the characteristics of the NADYA registry from its beginning. 18 experts from hospitals all over Spain have participated. The internal analysis seems to be positive, presenting the registry as having important resources. The external analysis did not show a great number of threats, there are very potent factors, "the voluntariness" of the registry and the "dependence on external financing". The opportunities identified are important. The recommendations are aimed at stabilizing the system by decreasing the threats as one of the main focus of the strategies to develop as well as promoting the items identified as opportunities and strengths. The analysis shows that the NADYA register shows a big potentiality for improvement. The proposed recommendations should be structured in order to stay on the track of development and quality improvement that has characterized the NADYA register from the beginning.

  14. 46,XX T testicular disorder of sex development. Case report.

    PubMed

    Pastor Guzmán, José María; Pastor Navarro, Hector; Quintanilla Mata, María Luisa; Carrión López, Pedro; Martínez Ruíz, Jesús; Martínez Sanchiz, Carlos; Perán Teruel, Miguel; Virseda Rodríguez, Julio Antonio

    2011-06-01

    We present a case of X-Y translocation with male phenotype (46,XX testicular disorder of sex development) and review the literature. Disorders of sex development with mismatch of genetic, gonadal and phenotypic sex are quite rare, and some are due to genetic or chromosomal abnormalities. The karyotype was investigated by a cytogenetic study of peripheral blood (phytohemagglutinin-timulated lymphocyte culture over 72 hours). G-banding analysis of 25 metaphases showed a 46,XX chromosome constitution (46 chromosomes with XX sexual composition). Fluorescence in situ hybridization (FISH) analysis with probes for X centromeres and the sex-determining region of the Y chromosome (SRY) (testis-determining factor gene) showed two X chromosomes. The analysis also showed the SRY signal in the telomeric region of the short arm of one of the chromosomes. In recent years, a number of other genes involved in disorders of sex development in animals and humans have also been identified. Genetic defects in the peptide hormone receptors, members of the steroid receptor superfamily, and other transcription factors, as well as any of a series of enzymes and cofactors involved in steroid biosynthesis can cause abnormal determination and differentiation. Although chromosomal abnormalities are rarely present in patients with apparently normal external genitalia, they should be considered in urology consultations by adolescents and adults, particularly in the investigation of gynecomastia or infertility.

  15. Redox environment in stem and differentiated cells: A quantitative approach.

    PubMed

    Lyublinskaya, O G; Ivanova, Ju S; Pugovkina, N A; Kozhukharova, I V; Kovaleva, Z V; Shatrova, A N; Aksenov, N D; Zenin, V V; Kaulin, Yu A; Gamaley, I A; Nikolsky, N N

    2017-08-01

    Stem cells are believed to maintain a specific intracellular redox status through a combination of enhanced removal capacity and limited production of ROS. In the present study, we challenge this assumption by developing a quantitative approach for the analysis of the pro- and antioxidant ability of human embryonic stem cells in comparison with their differentiated descendants, as well as adult stem and non-stem cells. Our measurements showed that embryonic stem cells are characterized by low ROS level, low rate of extracellular hydrogen peroxide removal and low threshold for peroxide-induced cytotoxicity. However, biochemical normalization of these parameters to cell volume/protein leads to matching of normalized values in stem and differentiated cells and shows that tested in the present study cells (human embryonic stem cells and their fibroblast-like progenies, adult mesenchymal stem cells, lymphocytes, HeLa) maintain similar intracellular redox status. Based on these observations, we propose to use ROS concentration averaged over the cell volume instead of ROS level as a measure of intracellular redox balance. We show that attempts to use ROS level for comparative analysis of redox status of morphologically different cells could lead to false conclusions. Methods for the assessment of ROS concentration based on flow cytometry analysis with the use of H 2 DCFDA dye and HyPer, genetically encoded probe for hydrogen peroxide, are discussed. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  16. Association between omega-3 fatty acids consumption and the risk of type 2 diabetes: A meta-analysis of cohort studies.

    PubMed

    Chen, Cai; Yang, Yan; Yu, Xuefeng; Hu, Shuhong; Shao, Shiying

    2017-07-01

    Epidemiological evidence for the effect of omega-3 fatty acids on the risk of type 2 diabetes is controversial. A meta-analysis based on prospective cohorts was carried out to evaluate this issue. Pooled diabetic risk was calculated using a fixed or random effects model. The dose-response relationship was assessed by meta-regression analysis. The study showed that consumption of single omega-3 was associated with an increased risk of type 2 diabetes (relative risk [RR] = 1.45, P < 0.001); whereas the RR for mixed omega-3 was statistically insignificant. The dose-response curve presented an inverted U-shape of diabetes risk corresponding to the dose of omega-3 consumption. Subanalysis showed that omega-3 was inversely associated with type 2 diabetes risk in Asians (RR = 0.82, P < 0.001); whereas the risk was increased in Westerners (RR = 1.30, P < 0.001). Studies with follow-up duration ≥16 years and baseline age ≥54 years showed a positive association between type 2 diabetes risk and omega-3 intake. The present findings suggest that dosage and composition of omega-3, ethnicity, trial duration, and age could influence the effect of omega-3 on type 2 diabetes progression. © 2016 The Authors. Journal of Diabetes Investigation published by Asian Association for the Study of Diabetes (AASD) and John Wiley & Sons Australia, Ltd.

  17. The novel ER membrane protein PRO41 is essential for sexual development in the filamentous fungus Sordaria macrospora.

    PubMed

    Nowrousian, Minou; Frank, Sandra; Koers, Sandra; Strauch, Peter; Weitner, Thomas; Ringelberg, Carol; Dunlap, Jay C; Loros, Jennifer J; Kück, Ulrich

    2007-05-01

    The filamentous fungus Sordaria macrospora develops complex fruiting bodies (perithecia) to propagate its sexual spores. Here, we present an analysis of the sterile mutant pro41 that is unable to produce mature fruiting bodies. The mutant carries a deletion of 4 kb and is complemented by the pro41 open reading frame that is contained within the region deleted in the mutant. In silico analyses predict PRO41 to be an endoplasmic reticulum (ER) membrane protein, and a PRO41-EGFP fusion protein colocalizes with ER-targeted DsRED. Furthermore, Western blot analysis shows that the PRO41-EGFP fusion protein is present in the membrane fraction. A fusion of the predicted N-terminal signal sequence of PRO41 with EGFP is secreted out of the cell, indicating that the signal sequence is functional. pro41 transcript levels are upregulated during sexual development. This increase in transcript levels was not observed in the sterile mutant pro1 that lacks a transcription factor gene. Moreover, microarray analysis of gene expression in the mutants pro1, pro41 and the pro1/41 double mutant showed that pro41 is partly epistatic to pro1. Taken together, these data show that PRO41 is a novel ER membrane protein essential for fruiting body formation in filamentous fungi.

  18. The novel ER membrane protein PRO41 is essential for sexual development in the filamentous fungus Sordaria macrospora

    PubMed Central

    Nowrousian, Minou; Frank, Sandra; Koers, Sandra; Strauch, Peter; Weitner, Thomas; Ringelberg, Carol; Dunlap, Jay C.; Loros, Jennifer J.; Kück, Ulrich

    2013-01-01

    Summary The filamentous fungus Sordaria macrospora develops complex fruiting bodies (perithecia) to propagate its sexual spores. Here, we present an analysis of the sterile mutant pro41 that is unable to produce mature fruiting bodies. The mutant carries a deletion of 4 kb and is complemented by the pro41 open reading frame that is contained within the region deleted in the mutant. In silico analyses predict PRO41 to be an endoplasmic reticulum (ER) membrane protein, and a PRO41–EGFP fusion protein colocalizes with ER-targeted DsRED. Furthermore, Western blot analysis shows that the PRO41–EGFP fusion protein is present in the membrane fraction. A fusion of the predicted N-terminal signal sequence of PRO41 with EGFP is secreted out of the cell, indicating that the signal sequence is functional. pro41 transcript levels are upregulated during sexual development. This increase in transcript levels was not observed in the sterile mutant pro1 that lacks a transcription factor gene. Moreover, microarray analysis of gene expression in the mutants pro1, pro41 and the pro1/41 double mutant showed that pro41 is partly epistatic to pro1. Taken together, these data show that PRO41 is a novel ER membrane protein essential for fruiting body formation in filamentous fungi. PMID:17501918

  19. Eigenvalue-eigenvector decomposition (EED) analysis of dissimilarity and covariance matrix obtained from total synchronous fluorescence spectral (TSFS) data sets of herbal preparations: Optimizing the classification approach

    NASA Astrophysics Data System (ADS)

    Tarai, Madhumita; Kumar, Keshav; Divya, O.; Bairi, Partha; Mishra, Kishor Kumar; Mishra, Ashok Kumar

    2017-09-01

    The present work compares the dissimilarity and covariance based unsupervised chemometric classification approaches by taking the total synchronous fluorescence spectroscopy data sets acquired for the cumin and non-cumin based herbal preparations. The conventional decomposition method involves eigenvalue-eigenvector analysis of the covariance of the data set and finds the factors that can explain the overall major sources of variation present in the data set. The conventional approach does this irrespective of the fact that the samples belong to intrinsically different groups and hence leads to poor class separation. The present work shows that classification of such samples can be optimized by performing the eigenvalue-eigenvector decomposition on the pair-wise dissimilarity matrix.

  20. Gender-Related Differences in Pelvic Morphometrics of the Retriever Dog Breed.

    PubMed

    Nganvongpanit, K; Pitakarnnop, T; Buddhachat, K; Phatsara, M

    2017-02-01

    This study presents the results from a morphometric analysis of 52 dry Retriever dog pelvic bones (30 male, 22 female). A total of 20 parameters were measured using an osteometric board and digital vernier caliper. Six parameters were found to be significantly higher (P < 0.05) in males than in females, while one parameter was significantly higher (P < 0.05) in females than in males. However, none of the measured parameters demonstrated clear cut-off values with no intersect between males and females. Therefore, we generated a stepwise discriminant analysis from all 20 parameters in order to develop a possible working equation to discriminate gender from a dog pelvic bone. Stepwise discriminant analysis was used to create a discrimination function: Y = [82.1*PS/AII] - [50.72*LIS/LI] - [23.09*OTD/SP] + [7.69*SP/IE] + [6.52*IC/OW] + [7.67*ISA/OW] + [20.77*AII/PS] + [504.71*OW/ISA] - [90.84*PS/ISA] - [148.95], which showed an accuracy rate of 86.27%. This is the first study presenting an equation/function for use in discriminating gender from a dog's pelvic measurements. The results can be used in veterinary forensic anthropology and also show that a dog's pelvis presents sexual dimorphisms, as in humans. © 2016 Blackwell Verlag GmbH.

  1. Exploring cosmic origins with CORE: Mitigation of systematic effects

    NASA Astrophysics Data System (ADS)

    Natoli, P.; Ashdown, M.; Banerji, R.; Borrill, J.; Buzzelli, A.; de Gasperis, G.; Delabrouille, J.; Hivon, E.; Molinari, D.; Patanchon, G.; Polastri, L.; Tomasi, M.; Bouchet, F. R.; Henrot-Versillé, S.; Hoang, D. T.; Keskitalo, R.; Kiiveri, K.; Kisner, T.; Lindholm, V.; McCarthy, D.; Piacentini, F.; Perdereau, O.; Polenta, G.; Tristram, M.; Achucarro, A.; Ade, P.; Allison, R.; Baccigalupi, C.; Ballardini, M.; Banday, A. J.; Bartlett, J.; Bartolo, N.; Basak, S.; Baumann, D.; Bersanelli, M.; Bonaldi, A.; Bonato, M.; Boulanger, F.; Brinckmann, T.; Bucher, M.; Burigana, C.; Cai, Z.-Y.; Calvo, M.; Carvalho, C.-S.; Castellano, M. G.; Challinor, A.; Chluba, J.; Clesse, S.; Colantoni, I.; Coppolecchia, A.; Crook, M.; D'Alessandro, G.; de Bernardis, P.; De Zotti, G.; Di Valentino, E.; Diego, J.-M.; Errard, J.; Feeney, S.; Fernandez-Cobos, R.; Finelli, F.; Forastieri, F.; Galli, S.; Genova-Santos, R.; Gerbino, M.; González-Nuevo, J.; Grandis, S.; Greenslade, J.; Gruppuso, A.; Hagstotz, S.; Hanany, S.; Handley, W.; Hernandez-Monteagudo, C.; Hervías-Caimapo, C.; Hills, M.; Keihänen, E.; Kitching, T.; Kunz, M.; Kurki-Suonio, H.; Lamagna, L.; Lasenby, A.; Lattanzi, M.; Lesgourgues, J.; Lewis, A.; Liguori, M.; López-Caniego, M.; Luzzi, G.; Maffei, B.; Mandolesi, N.; Martinez-González, E.; Martins, C. J. A. P.; Masi, S.; Matarrese, S.; Melchiorri, A.; Melin, J.-B.; Migliaccio, M.; Monfardini, A.; Negrello, M.; Notari, A.; Pagano, L.; Paiella, A.; Paoletti, D.; Piat, M.; Pisano, G.; Pollo, A.; Poulin, V.; Quartin, M.; Remazeilles, M.; Roman, M.; Rossi, G.; Rubino-Martin, J.-A.; Salvati, L.; Signorelli, G.; Tartari, A.; Tramonte, D.; Trappe, N.; Trombetti, T.; Tucker, C.; Valiviita, J.; Van de Weijgaert, R.; van Tent, B.; Vennin, V.; Vielva, P.; Vittorio, N.; Wallis, C.; Young, K.; Zannoni, M.

    2018-04-01

    We present an analysis of the main systematic effects that could impact the measurement of CMB polarization with the proposed CORE space mission. We employ timeline-to-map simulations to verify that the CORE instrumental set-up and scanning strategy allow us to measure sky polarization to a level of accuracy adequate to the mission science goals. We also show how the CORE observations can be processed to mitigate the level of contamination by potentially worrying systematics, including intensity-to-polarization leakage due to bandpass mismatch, asymmetric main beams, pointing errors and correlated noise. We use analysis techniques that are well validated on data from current missions such as Planck to demonstrate how the residual contamination of the measurements by these effects can be brought to a level low enough not to hamper the scientific capability of the mission, nor significantly increase the overall error budget. We also present a prototype of the CORE photometric calibration pipeline, based on that used for Planck, and discuss its robustness to systematics, showing how CORE can achieve its calibration requirements. While a fine-grained assessment of the impact of systematics requires a level of knowledge of the system that can only be achieved in a future study phase, the analysis presented here strongly suggests that the main areas of concern for the CORE mission can be addressed using existing knowledge, techniques and algorithms.

  2. Study of arsenopyrite weathering products in mine wastes from abandoned tungsten and tin exploitations.

    PubMed

    Murciego, A; Alvarez-Ayuso, E; Pellitero, E; Rodríguez, Ma A; García-Sánchez, A; Tamayo, A; Rubio, J; Rubio, F; Rubin, J

    2011-02-15

    Arsenopyrite-rich wastes from abandoned tungsten and tin exploitations were studied to determine the composition and characteristics of the secondary phases formed under natural weathering conditions so as to assess their potential environmental risk. Representative weathered arsenopyrite-bearing rock wastes collected from the mine dumps were analysed using the following techniques: X-ray powder diffraction (XRD) analysis, polarizing microscopy analysis, electron microprobe analysis (EMPA) and microRaman and Mössbauer spectroscopies. Scorodite, pharmacosiderite and amorphous ferric arsenates (AFA) with Fe/As molar ratios in the range 1.2-2.5 were identified as secondary arsenic products. The former showed to be the most abundant and present in the different studied mining areas. Its chemical composition showed to vary in function of the original surrounding rock mineralogy in such a way that phosphoscorodite was found as the mineral variety present in apatite-containing geoenvirons. Other ever-present weathering phases were goethite and hydrous ferric oxides (HFO), displaying, respectively, As retained amounts about 1 and 20% (expressed as As(2)O(5)). The low solubility of scorodite, the relatively low content of AFA and the formation of compounds of variable charge, mostly of amorphous nature, with high capacity to adsorb As attenuate importantly the dispersion of this element into the environment from these arsenopyrite-bearing wastes. Copyright © 2010 Elsevier B.V. All rights reserved.

  3. Cluster and principal component analysis based on SSR markers of Amomum tsao-ko in Jinping County of Yunnan Province

    NASA Astrophysics Data System (ADS)

    Ma, Mengli; Lei, En; Meng, Hengling; Wang, Tiantao; Xie, Linyan; Shen, Dong; Xianwang, Zhou; Lu, Bingyue

    2017-08-01

    Amomum tsao-ko is a commercial plant that used for various purposes in medicinal and food industries. For the present investigation, 44 germplasm samples were collected from Jinping County of Yunnan Province. Clusters analysis and 2-dimensional principal component analysis (PCA) was used to represent the genetic relations among Amomum tsao-ko by using simple sequence repeat (SSR) markers. Clustering analysis clearly distinguished the samples groups. Two major clusters were formed; first (Cluster I) consisted of 34 individuals, the second (Cluster II) consisted of 10 individuals, Cluster I as the main group contained multiple sub-clusters. PCA also showed 2 groups: PCA Group 1 included 29 individuals, PCA Group 2 included 12 individuals, consistent with the results of cluster analysis. The purpose of the present investigation was to provide information on genetic relationship of Amomum tsao-ko germplasm resources in main producing areas, also provide a theoretical basis for the protection and utilization of Amomum tsao-ko resources.

  4. Analysis for stresses and buckling of heated composite stiffened panels and other structures, phase 3

    NASA Technical Reports Server (NTRS)

    Viswanathan, A. V.; Tamekuni, M.

    1973-01-01

    Analytical methods based on linear theory are presented for predicting the thermal stresses in and the buckling of heated structures with arbitrary uniform cross section. The structure is idealized as an assemblage of laminated plate-strip elements, curved and planar, and beam elements. Uniaxially stiffened plates and shells of arbitrary cross section are typical examples. For the buckling analysis the structure or selected elements may be subjected to mechanical loads, in additional to thermal loads, in any desired combination of inplane transverse load and axial compression load. The analysis is also applicable to stiffened structures under inplane loads varying through the cross section, as in stiffened shells under bending. The buckling analysis is general and covers all modes of instability. The analysis has been applied to a limited number of problems and the results are presented. These while showing the validity and the applicability of the method do not reflect its full capability.

  5. Parametric and experimental analysis using a power flow approach

    NASA Technical Reports Server (NTRS)

    Cuschieri, J. M.

    1988-01-01

    Having defined and developed a structural power flow approach for the analysis of structure-borne transmission of structural vibrations, the technique is used to perform an analysis of the influence of structural parameters on the transmitted energy. As a base for comparison, the parametric analysis is first performed using a Statistical Energy Analysis approach and the results compared with those obtained using the power flow approach. The advantages of using structural power flow are thus demonstrated by comparing the type of results obtained by the two methods. Additionally, to demonstrate the advantages of using the power flow method and to show that the power flow results represent a direct physical parameter that can be measured on a typical structure, an experimental investigation of structural power flow is also presented. Results are presented for an L-shaped beam for which an analytical solution has already been obtained. Furthermore, the various methods available to measure vibrational power flow are compared to investigate the advantages and disadvantages of each method.

  6. Effect of polyamines on mechanical and structural properties of Bombyx mori silk.

    PubMed

    Yerra, Aparna; Mysarla, Danti Kumari; Siripurapu, Prasanthi; Jha, Anjali; Valluri, Satyavathi V; Mamillapalli, Anitha

    2017-01-01

    Silkworm, Bombyx mori (B. mori) belongs to the Lepidoptera family. The silk produced from this insect, mulberry silk, gained lot of importance as a fabric. Silk is being exploited as a biomaterial due to its surprising strength and biocompatibility. Polyamines (PA) are important cell growth regulators. In the present work the effect of treatment of polyamines, putrescine (Put), spermidine (Spd), and spermine (Spm) on the quantity and quality of silk produced was assessed. Results showed that exogenous feeding of Spd at a concentration of 50 µM increased fiber length significantly. Analysis by Fourier transform infrared (FTIR) on the properties of silk obtained from Spd treated silkworms revealed an increase in percentage of absorption with no difference in peak positions of amide I and amide III groups. Scanning electron microscopy (SEM) revealed an increase in diameter of silk. Further, analysis at molecular level showed an increase in fibroin expression in Spd treated silk glands. However, the Spd treatment showed no significant difference with respect to fibroin to sericin ratio per unit weight of cocoon, silk tenacity, and percent elongation. Thus, the present results show that polyamine treatment would influence silk quality at structural, mechanical, and molecular level in the Bombyx mori, which can be exploited in silk biomaterial production. © 2016 Wiley Periodicals, Inc.

  7. Pharmacokinetic and pharmacodynamic model for analysis of adalimumab administered for Crohn's disease.

    PubMed

    Kimura, Koji; Yoshida, Atsushi; Takayanagi, Risa; Yamada, Yasuhiko

    2018-05-23

    Adalimumab (ADA) is used as a therapeutic agent for Crohn's disease (CD). Although that dosage regimen has been established through clinical trial experience, it has not been analyzed theoretically. In the present study, we analyzed of sequential changes of the Crohn's disease activity index (CDAI) after repeated administrations of ADA using a pharmacokinetic and pharmacodynamic model. In addition, we analyzed the validity of the dosage regimen, and potential efficacy gained by increasing the dose and reducing the interval of administration. The sequential changes in CDAI values obtained with our model were in good agreement with observed CDAI values, which was considered to show the validity of our analysis. We considered that our results showed the importance of the loading dose of ADA to obtain remission in an early stage of active CD. In addition, we showed that patients who have an incomplete response to ADA can obtain similar efficacy from increasing the dose and reducing the dose interval. In conclusion, our results showed that the present model may be applied to predict the CDAI values of ADA for CD. They indicated the validity of the dosage regimen, as well as the efficacy of increasing the dose and reducing the dose interval. This article is protected by copyright. All rights reserved.

  8. Laser-Based Trespassing Prediction in Restrictive Environments: A Linear Approach

    PubMed Central

    Cheein, Fernando Auat; Scaglia, Gustavo

    2012-01-01

    Stationary range laser sensors for intruder monitoring, restricted space violation detections and workspace determination are extensively used in risky environments. In this work we present a linear based approach for predicting the presence of moving agents before they trespass a laser-based restricted space. Our approach is based on the Taylor's series expansion of the detected objects' movements. The latter makes our proposal suitable for embedded applications. In the experimental results (carried out in different scenarios) presented herein, our proposal shows 100% of effectiveness in predicting trespassing situations. Several implementation results and statistics analysis showing the performance of our proposal are included in this work.

  9. [Preoperative psychoprophylaxis in childhood. Results of a hospital program].

    PubMed

    Admetlla i Admetlla, I A; Jover i Fulgueira, S

    1988-05-01

    Results of a surgical psychoprophylaxis program, theoretically and technically framed within psychoanalytic theory is presented. It also comprises a description of the method used, as well as criteria by which authors have determined whether or not a child is ready for surgery. Results obtained with 134 children and a description of those who showed post-surgical disturbances are presented. Analysis is carried out of the percentage of disorders according to age group, showing that highest risk is among children up to five years of age, coinciding with the finding put forth by other authors. Finally some conclusions in relation to prevention of psychologic iatrogenic disorders in pediatric surgery are drawn.

  10. More than pop culture: depictions of HIV in the media and the effect on viewer's perception of risk.

    PubMed

    Johnson, Malynnda A

    2013-01-01

    When young adults are questioned about where they gain their knowledge of HIV, overwhelmingly popular media (including television) is reported. Thus, the goal of this article is to question how media is used to educate and influence young people's present perceptions of HIV/AIDS. Narrative analysis of popular prime time shows was used focusing on the story lines and characters used to introduce the topic, as well as the myths and facts about HIV. Results presented provide researchers a clearer insight to how popular shows discuss HIV/AIDS while also highlighting the ways Social Cognitive Theory can still be utilized.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sigeti, David E.; Pelak, Robert A.

    We present a Bayesian statistical methodology for identifying improvement in predictive simulations, including an analysis of the number of (presumably expensive) simulations that will need to be made in order to establish with a given level of confidence that an improvement has been observed. Our analysis assumes the ability to predict (or postdict) the same experiments with legacy and new simulation codes and uses a simple binomial model for the probability, {theta}, that, in an experiment chosen at random, the new code will provide a better prediction than the old. This model makes it possible to do statistical analysis withmore » an absolute minimum of assumptions about the statistics of the quantities involved, at the price of discarding some potentially important information in the data. In particular, the analysis depends only on whether or not the new code predicts better than the old in any given experiment, and not on the magnitude of the improvement. We show how the posterior distribution for {theta} may be used, in a kind of Bayesian hypothesis testing, both to decide if an improvement has been observed and to quantify our confidence in that decision. We quantify the predictive probability that should be assigned, prior to taking any data, to the possibility of achieving a given level of confidence, as a function of sample size. We show how this predictive probability depends on the true value of {theta} and, in particular, how there will always be a region around {theta} = 1/2 where it is highly improbable that we will be able to identify an improvement in predictive capability, although the width of this region will shrink to zero as the sample size goes to infinity. We show how the posterior standard deviation may be used, as a kind of 'plan B metric' in the case that the analysis shows that {theta} is close to 1/2 and argue that such a plan B should generally be part of hypothesis testing. All the analysis presented in the paper is done with a general beta-function prior for {theta}, enabling sequential analysis in which a small number of new simulations may be done and the resulting posterior for {theta} used as a prior to inform the next stage of power analysis.« less

  12. Application-Specific Graph Sampling for Frequent Subgraph Mining and Community Detection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Purohit, Sumit; Choudhury, Sutanay; Holder, Lawrence B.

    Graph mining is an important data analysis methodology, but struggles as the input graph size increases. The scalability and usability challenges posed by such large graphs make it imperative to sample the input graph and reduce its size. The critical challenge in sampling is to identify the appropriate algorithm to insure the resulting analysis does not suffer heavily from the data reduction. Predicting the expected performance degradation for a given graph and sampling algorithm is also useful. In this paper, we present different sampling approaches for graph mining applications such as Frequent Subgrpah Mining (FSM), and Community Detection (CD). Wemore » explore graph metrics such as PageRank, Triangles, and Diversity to sample a graph and conclude that for heterogeneous graphs Triangles and Diversity perform better than degree based metrics. We also present two new sampling variations for targeted graph mining applications. We present empirical results to show that knowledge of the target application, along with input graph properties can be used to select the best sampling algorithm. We also conclude that performance degradation is an abrupt, rather than gradual phenomena, as the sample size decreases. We present the empirical results to show that the performance degradation follows a logistic function.« less

  13. A viable circulating tumor cell isolation device with high retrieval efficiency using a reversibly deformable membrane barrier

    NASA Astrophysics Data System (ADS)

    Kim, Yoonji; Bu, Jiyoon; Cho, Young-Ho; Son, Il Tae; Kang, Sung-Bum

    2017-02-01

    Circulating tumor cells (CTCs) contain prognostic information of the tumor, since they shed from the primary tumor and invade into the bloodstream. Therefore, the viable isolation is necessary for a consequent analysis of CTCs. Here, we present a device for the viable isolation and efficient retrieval of CTCs using slanted slot filters, formed by a reversibly deformable membrane barrier. Conventional filters have difficulties in retrieving captured cells, since they easily clog the slots. Moreover, large stress concentration at the sharp edges of squared slots, causes cell lysis. In contrast, the present device shows over 94% of high retrieval efficiency, since the slots can be opened simply by relieving the pressure. Furthermore, the inflated membrane barrier naturally forms the slanted slots, thus reducing the cell damage. By using cancer cell lines, we verified that the present device successfully isolate targeted cells, even at an extremely low concentrations (~10 cells/0.1 ml). In the clinical study, 85.7% of patients initially showed CTC positive while the numbers generally decreased after the surgery. We have also proved that the number of CTCs were highly correlated with tumour invasiveness. Therefore, the present device has potential for use in cancer diagnosis, surgical validation, and invasiveness analysis.

  14. Local loss and spatial homogenization of plant diversity reduce ecosystem multifunctionality

    USDA-ARS?s Scientific Manuscript database

    Experimental studies show that local plant species loss decreases ecosystem functioning and services, but it remains unclear how other changes in biodiversity, such as spatial homogenization, alter multiple processes (multifunctionality) in natural ecosystems. We present a global analysis of eight ...

  15. Design and Field Procedures in the US National Comorbidity Survey Replication Adolescent Supplement (NCS-A)

    PubMed Central

    Kessler, Ronald C.; Avenevoli, Shelli; Costello, E. Jane; Green, Jennifer Greif; Gruber, Michael J.; Heeringa, Steven; Merikangas, Kathleen R.; Pennell, Beth-Ellen; Sampson, Nancy A.; Zaslavsky, Alan M.

    2009-01-01

    An overview is presented of the design and field procedures of the US National Comorbidity Survey Replication Adolescent Supplement (NCS-A), a US face-to-face household survey of the prevalence and correlates of DSM-IV mental disorders. The survey was based on a dual-frame design that included 904 adolescent residents of the households that participated in the US National Comorbidity Survey Replication (85.9% response rate) and 9,244 adolescent students selected from a nationally representative sample of 320 schools (74.7% response rate). After expositing the logic of dual-frame designs, comparisons are presented of sample and population distributions on Census socio-demographic variables and, in the school sample, school characteristics. These document only minor differences between the samples and the population. The results of statistical analysis of the bias-efficiency trade-off in weight trimming are then presented. These show that modest trimming meaningfully reduces mean squared error. Analysis of comparative sample efficiency shows that the household sample is more efficient than the school sample, leading to the household sample getting a higher weight relative to its size in the consolidated sample relative to the school sample. Taken together, these results show that the NCS-A is an efficient sample of the target population with good representativeness on a range of socio-demographic and geographic variables. PMID:19507169

  16. Green synthesis, characterization and antibacterial efficacy of palladium nanoparticles synthesized using Filicium decipiens leaf extract

    NASA Astrophysics Data System (ADS)

    Sharmila, G.; Farzana Fathima, M.; Haries, S.; Geetha, S.; Manoj Kumar, N.; Muthukumaran, C.

    2017-06-01

    Synthesis of metal nanoparticles through green chemistry route is an emerging eco-friendly approach in the present days. An eco-friendly, biogenic synthesis of palladium nanoparticles (PdNPs) using Filicium decipiens leaf extract was reported in the present study. The synthesized PdNPs were characterized by UV-visible spectroscopy, Transmission electron microscopy (TEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). The PdNPs formation was confirmed by UV-visible spectrophotometer and spherical shaped PdNPs with size range of 2-22 nm was observed in TEM analysis. Energy dispersive X-ray spectroscopy (EDS) analysis confirmed the presence of palladium in the synthesized nanoparticles. The crystalline nature of PdNPs was confirmed by XRD pattern and compared with the standard. The phytochemicals and proteins were identified by their functional groups in FT-IR spectrum and revealed the amide, amine groups present in F. decipiens may have involved in the bio-reduction reaction for PdNPs synthesis. Prepared PdNPs showed potential antibacterial activity against both Gram-positive and Gram-negative bacteria. F. decipiens leaf extract based PdNPs showed high bactericidal activity against Escherichia coli, Pseudomonas aeruginosa as compared to Staphylococcus aureus and Bacillus subtilis Results showed that phytochemicals rich F. decipiens leaf extract may be utilized as an effective non-toxic reducing agent for PdNPs synthesis and prepared PdNPs may useful in biomedical applications.

  17. Reassessing the 3/4 view effect in face recognition.

    PubMed

    Liu, Chang Hong; Chaudhuri, Avi

    2002-02-01

    It is generally accepted that unfamiliar faces are better recognized if presented in 3/4 view. A common interpretation of this result is that the 3/4 view represents a canonical view for faces. This article presents a critical review of this claim. Two kinds of advantage, in which a 3/4 view either generalizes better to a different view or produces better recognition in the same view, are discussed. Our analysis of the literature shows that the first effect almost invariably depended on different amounts of angular rotation that was present between learning and test views. The advantage usually vanished when angular rotation was equalized between conditions. Reports in favor of the second effect are scant and can be countered by studies reporting negative findings. To clarify this ambiguity, we conducted a recognition experiment. Subjects were trained and tested on the same three views (full-face, 3/4 and profile). The results showed no difference between the three view conditions. Our analysis of the literature, along with the new results, shows that the evidence for a 3/4 view advantage in both categories is weak at best. We suggest that a better predictor of performance for recognition in different views is the angular difference between learning and test views. For recognition in the same view, there may be a wide range of views whose effectiveness is comparable to the 3/4 view.

  18. Radiometric 81Kr dating identifies 120,000-year-old ice at Taylor Glacier, Antarctica

    PubMed Central

    Buizert, Christo; Baggenstos, Daniel; Jiang, Wei; Purtschert, Roland; Petrenko, Vasilii V.; Lu, Zheng-Tian; Müller, Peter; Kuhl, Tanner; Lee, James; Severinghaus, Jeffrey P.; Brook, Edward J.

    2014-01-01

    We present successful 81Kr-Kr radiometric dating of ancient polar ice. Krypton was extracted from the air bubbles in four ∼350-kg polar ice samples from Taylor Glacier in the McMurdo Dry Valleys, Antarctica, and dated using Atom Trap Trace Analysis (ATTA). The 81Kr radiometric ages agree with independent age estimates obtained from stratigraphic dating techniques with a mean absolute age offset of 6 ± 2.5 ka. Our experimental methods and sampling strategy are validated by (i) 85Kr and 39Ar analyses that show the samples to be free of modern air contamination and (ii) air content measurements that show the ice did not experience gas loss. We estimate the error in the 81Kr ages due to past geomagnetic variability to be below 3 ka. We show that ice from the previous interglacial period (Marine Isotope Stage 5e, 130–115 ka before present) can be found in abundance near the surface of Taylor Glacier. Our study paves the way for reliable radiometric dating of ancient ice in blue ice areas and margin sites where large samples are available, greatly enhancing their scientific value as archives of old ice and meteorites. At present, ATTA 81Kr analysis requires a 40–80-kg ice sample; as sample requirements continue to decrease, 81Kr dating of ice cores is a future possibility. PMID:24753606

  19. Radiometric 81Kr dating identifies 120,000-year-old ice at Taylor Glacier, Antarctica.

    PubMed

    Buizert, Christo; Baggenstos, Daniel; Jiang, Wei; Purtschert, Roland; Petrenko, Vasilii V; Lu, Zheng-Tian; Müller, Peter; Kuhl, Tanner; Lee, James; Severinghaus, Jeffrey P; Brook, Edward J

    2014-05-13

    We present successful (81)Kr-Kr radiometric dating of ancient polar ice. Krypton was extracted from the air bubbles in four ∼350-kg polar ice samples from Taylor Glacier in the McMurdo Dry Valleys, Antarctica, and dated using Atom Trap Trace Analysis (ATTA). The (81)Kr radiometric ages agree with independent age estimates obtained from stratigraphic dating techniques with a mean absolute age offset of 6 ± 2.5 ka. Our experimental methods and sampling strategy are validated by (i) (85)Kr and (39)Ar analyses that show the samples to be free of modern air contamination and (ii) air content measurements that show the ice did not experience gas loss. We estimate the error in the (81)Kr ages due to past geomagnetic variability to be below 3 ka. We show that ice from the previous interglacial period (Marine Isotope Stage 5e, 130-115 ka before present) can be found in abundance near the surface of Taylor Glacier. Our study paves the way for reliable radiometric dating of ancient ice in blue ice areas and margin sites where large samples are available, greatly enhancing their scientific value as archives of old ice and meteorites. At present, ATTA (81)Kr analysis requires a 40-80-kg ice sample; as sample requirements continue to decrease, (81)Kr dating of ice cores is a future possibility.

  20. An Oleuropein β-Glucosidase from Olive Fruit Is Involved in Determining the Phenolic Composition of Virgin Olive Oil

    PubMed Central

    Velázquez-Palmero, David; Romero-Segura, Carmen; García-Rodríguez, Rosa; Hernández, María L.; Vaistij, Fabián E.; Graham, Ian A.; Pérez, Ana G.; Martínez-Rivas, José M.

    2017-01-01

    Phenolic composition of virgin olive oil is determined by the enzymatic and/or chemical reactions that take place during olive fruit processing. Of these enzymes, β-glucosidase activity plays a relevant role in the transformation of the phenolic glycosides present in the olive fruit, generating different secoiridoid derivatives. The main goal of the present study was to characterize olive fruit β-glucosidase genes and enzymes responsible for the phenolic composition of virgin olive oil. To achieve that, we have isolated an olive β-glucosidase gene from cultivar Picual (OepGLU), expressed in Nicotiana benthamiana leaves and purified its corresponding recombinant enzyme. Western blot analysis showed that recombinant OepGLU protein is detected by an antibody raised against the purified native olive mesocarp β-glucosidase enzyme, and exhibits a deduced molecular mass of 65.0 kDa. The recombinant OepGLU enzyme showed activity on the major olive phenolic glycosides, with the highest levels with respect to oleuropein, followed by ligstroside and demethyloleuropein. In addition, expression analysis showed that olive GLU transcript level in olive fruit is spatially and temporally regulated in a cultivar-dependent manner. Furthermore, temperature, light and water regime regulate olive GLU gene expression in olive fruit mesocarp. All these data are consistent with the involvement of OepGLU enzyme in the formation of the major phenolic compounds present in virgin olive oil. PMID:29163620

  1. A computational analysis subject to thermophysical aspects of Sisko fluid flow over a cylindrical surface

    NASA Astrophysics Data System (ADS)

    Awais, M.; Khalil-Ur-Rehman; Malik, M. Y.; Hussain, Arif; Salahuddin, T.

    2017-09-01

    The present analysis is devoted to probing the salient features of the mixed convection and non-linear thermal radiation effects on non-Newtonian Sisko fluid flow over a linearly stretching cylindrical surface. Properties of heat transfer are outlined via variable thermal conductivity and convective boundary conditions. The boundary layer approach is implemented to construct the mathematical model in the form of partial differential equations. Then, the requisite PDEs are transmuted into a complex ordinary differential system by invoking appropriate dimensionless variables. Solution of subsequent ODEs is obtained by utilizing the Runge-Kutta algorithm (fifth order) along with the shooting scheme. The graphical illustrations are presented to interpret the features of the involved pertinent flow parameters on concerning profiles. For a better description of the fluid flow, numerical variations in local skin friction coefficient and local Nusselt number are scrutinized in tables. From thorough analysis, it is inferred that the mixed convection parameter and the curvature parameter increase the velocity while temperature shows a different behavior. Additionally, both momentum and thermal distribution of fluid flow decrease with increasing values of the non-linearity index. Furthermore, variable thermal parameter and heat generation/absorption parameter amplify the temperature significantly. The skin friction is an increasing function of all momentum controlling parameters. The local Nusselt number also shows a similar behavior against heat radiation parameter and variable thermal conductivity parameter while it shows a dual nature for the heat generation/absorption parameter. Finally, the obtained results are validated by comparison with the existing literature and hence the correctness of the analysis is proved.

  2. Ottawa Ankle Rules and Subjective Surgeon Perception to Evaluate Radiograph Necessity Following Foot and Ankle Sprain

    PubMed Central

    Pires, RES; Pereira, AA; Abreu-e-Silva, GM; Labronici, PJ; Figueiredo, LB; Godoy-Santos, AL; Kfuri, M

    2014-01-01

    Background: Foot and ankle injuries are frequent in emergency departments. Although only a few patients with foot and ankle sprain present fractures and the fracture patterns are almost always simple, lack of fracture diagnosis can lead to poor functional outcomes. Aim: The present study aims to evaluate the reliability of the Ottawa ankle rules and the orthopedic surgeon subjective perception to assess foot and ankle fractures after sprains. Subjects and Methods: A cross-sectional study was conducted from July 2012 to December 2012. Ethical approval was granted. Two hundred seventy-four adult patients admitted to the emergency department with foot and/or ankle sprain were evaluated by an orthopedic surgeon who completed a questionnaire prior to radiographic assessment. The Ottawa ankle rules and subjective perception of foot and/or ankle fractures were evaluated on the questionnaire. Results: Thirteen percent (36/274) patients presented fracture. Orthopedic surgeon subjective analysis showed 55.6% sensitivity, 90.1% specificity, 46.5% positive predictive value and 92.9% negative predictive value. The general orthopedic surgeon opinion accuracy was 85.4%. The Ottawa ankle rules presented 97.2% sensitivity, 7.8% specificity, 13.9% positive predictive value, 95% negative predictive value and 19.9% accuracy respectively. Weight-bearing inability was the Ottawa ankle rule item that presented the highest reliability, 69.4% sensitivity, 61.6% specificity, 63.1% accuracy, 21.9% positive predictive value and 93% negative predictive value respectively. Conclusion: The Ottawa ankle rules showed high reliability for deciding when to take radiographs in foot and/or ankle sprains. Weight-bearing inability was the most important isolated item to predict fracture presence. Orthopedic surgeon subjective analysis to predict fracture possibility showed a high specificity rate, representing a confident method to exclude unnecessary radiographic exams. PMID:24971221

  3. Electropalatography in home training of retracted articulation in a Swedish child with cleft palate: effect on articulation pattern and speech.

    PubMed

    Lohmander, Anette; Henriksson, Cecilia; Havstam, Christina

    2010-12-01

    The aim was to evaluate the effectiveness of electropalatography (EPG) in home training of persistent articulation errors in an 11-year-old Swedish girl born with isolated cleft palate. The /t/ and /s/ sounds were trained in a single subject design across behaviours during an eight month period using a portable training unit (PTU). Both EPG analysis and perceptual analysis showed an improvement in the production of /t/ and /s/ in words and sentences after therapy. Analysis of tongue-contact patterns showed that the participant had more normal articulatory patterns of /t/ and /s/ after just 2 months (after approximately 8 hours of training) respectively. No statistically significant transfer by means of intelligibility in connected speech was found. The present results show that EPG home training can be a sufficient method for treating persistent speech disorders associated with cleft palate. Methods for transfer from function (articulation) to activity (intelligibility) need to be explored.

  4. Thermo-economic analysis of a trigeneration HCPVT power plant

    NASA Astrophysics Data System (ADS)

    Selviaridis, Angelos; Burg, Brian R.; Wallerand, Anna Sophia; Maréchal, François; Michel, Bruno

    2015-09-01

    The increasing need for electricity and heat in a growing global economy must be combined with CO2 emissions reduction, in order to limit the human influence on the environment. This calls for energy-efficient and cost-competitive renewable energy systems that are able to satisfy both pressing needs. A High-Concentration Photovoltaic Thermal (HCPVT) system is a cogeneration concept that shows promising potential in delivering electricity and heat in an efficient and cost-competitive manner. This study investigates the transient behavior of the HCPVT system and presents a thermo-economic analysis of a MW-scale trigeneration (electricity, heating and cooling) power plant. Transient simulations show a fast dynamic response of the system which results in short heat-up intervals, maximizing heat recuperation throughout the day. Despite suboptimal coupling between demand and supply, partial heat utilization throughout the year and low COP of commercially available devices for the conversion of heat into cooling, the thermo-economic analysis shows promising economic behavior, with a levelized cost of electricity close to current retail prices.

  5. Quantification and Analysis of Offensive Situations in Different Formats of Sided Games In Soccer

    PubMed Central

    Garcia, Jorge Diaz-Cidoncha; Román, Ignacio Refoyo; Calleja-González, Julio; Dellal, Alexandre

    2014-01-01

    There has been a lot of research that enabled soccer to improve: its technique, tactics and strategy through analysis and training. Nevertheless, players’ need to interact with each other turns any defending or attacking situation into complex solutions with a wide range of variables to be considered, in which the player is never isolated and must make the move that has the most positive impact on play. Fifty-four sided games played in three different formats (5v5, 7v7 and 9v9) and with two age groups (U9 and U14) were filmed at three soccer clubs in Spain in order to identify the most relevant attacking moves, from a technical and tactical perspective. This study used the observational method; it is descriptive and is applied through well-prepared systematic quantitative observation in a natural environment. A key part of the method involved viewing the match recordings and logging moves that had been categorised beforehand. Cohen’s Kappa analysis showed that the results for the most representative variables presented a substantial degree of concordance (0.61–0.80). The results show that there were significant variations depending on the game format, and the following study will present a description and analysis of the aspects that had considerable influence on attacking moves in different formats of sided games (5v5, 7v7 and 9v9). The study also presents various practical applications for the area of training and analysing both youth and professional soccer. PMID:25713680

  6. High-throughput analysis of the satellitome illuminates satellite DNA evolution

    NASA Astrophysics Data System (ADS)

    Ruiz-Ruano, Francisco J.; López-León, María Dolores; Cabrero, Josefa; Camacho, Juan Pedro M.

    2016-07-01

    Satellite DNA (satDNA) is a major component yet the great unknown of eukaryote genomes and clearly underrepresented in genome sequencing projects. Here we show the high-throughput analysis of satellite DNA content in the migratory locust by means of the bioinformatic analysis of Illumina reads with the RepeatExplorer and RepeatMasker programs. This unveiled 62 satDNA families and we propose the term “satellitome” for the whole collection of different satDNA families in a genome. The finding that satDNAs were present in many contigs of the migratory locust draft genome indicates that they show many genomic locations invisible by fluorescent in situ hybridization (FISH). The cytological pattern of five satellites showing common descent (belonging to the SF3 superfamily) suggests that non-clustered satDNAs can become into clustered through local amplification at any of the many genomic loci resulting from previous dissemination of short satDNA arrays. The fact that all kinds of satDNA (micro- mini- and satellites) can show the non-clustered and clustered states suggests that all these elements are mostly similar, except for repeat length. Finally, the presence of VNTRs in bacteria, showing similar properties to non-clustered satDNAs in eukaryotes, suggests that this kind of tandem repeats show common properties in all living beings.

  7. Analytical analysis and implementation of a low-speed high-torque permanent magnet vernier in-wheel motor for electric vehicle

    NASA Astrophysics Data System (ADS)

    Li, Jiangui; Wang, Junhua; Zhigang, Zhao; Yan, Weili

    2012-04-01

    In this paper, analytical analysis of the permanent magnet vernier (PMV) is presented. The key is to analytically solve the governing Laplacian/quasi-Poissonian field equations in the motor regions. By using the time-stepping finite element method, the analytical method is verified. Hence, the performances of the PMV machine are quantitatively compared with that of the analytical results. The analytical results agree well with the finite element method results. Finally, the experimental results are given to further show the validity of the analysis.

  8. Fault tree safety analysis of a large Li/SOCl(sub)2 spacecraft battery

    NASA Technical Reports Server (NTRS)

    Uy, O. Manuel; Maurer, R. H.

    1987-01-01

    The results of the safety fault tree analysis on the eight module, 576 F cell Li/SOCl2 battery on the spacecraft and in the integration and test environment prior to launch on the ground are presented. The analysis showed that with the right combination of blocking diodes, electrical fuses, thermal fuses, thermal switches, cell balance, cell vents, and battery module vents the probability of a single cell or a 72 cell module exploding can be reduced to .000001, essentially the probability due to explosion for unexplained reasons.

  9. Determining triple gauge boson couplings from Higgs data.

    PubMed

    Corbett, Tyler; Éboli, O J P; Gonzalez-Fraile, J; Gonzalez-Garcia, M C

    2013-07-05

    In the framework of effective Lagrangians with the SU(2)(L)×U(1)(Y) symmetry linearly realized, modifications of the couplings of the Higgs field to the electroweak gauge bosons are related to anomalous triple gauge couplings (TGCs). Here, we show that the analysis of the latest Higgs boson production data at the LHC and Tevatron give rise to strong bounds on TGCs that are complementary to those from direct TGC analysis. We present the constraints on TGCs obtained by combining all available data on direct TGC studies and on Higgs production analysis.

  10. Ockham's razor and Bayesian analysis. [statistical theory for systems evaluation

    NASA Technical Reports Server (NTRS)

    Jefferys, William H.; Berger, James O.

    1992-01-01

    'Ockham's razor', the ad hoc principle enjoining the greatest possible simplicity in theoretical explanations, is presently shown to be justifiable as a consequence of Bayesian inference; Bayesian analysis can, moreover, clarify the nature of the 'simplest' hypothesis consistent with the given data. By choosing the prior probabilities of hypotheses, it becomes possible to quantify the scientific judgment that simpler hypotheses are more likely to be correct. Bayesian analysis also shows that a hypothesis with fewer adjustable parameters intrinsically possesses an enhanced posterior probability, due to the clarity of its predictions.

  11. Chromosome rearrangements in canine fibrosarcomas.

    PubMed

    Sargan, D R; Milne, B S; Hernandez, J Aguirre; O'Brien, P C M; Ferguson-Smith, M A; Hoather, T; Dobson, J M

    2005-01-01

    We have previously reported the use of six- and seven-color paint sets in the analysis of canine soft tissue sarcomas. Here we combine this technique with flow sorting of translocation chromosomes, reverse painting, and polymerase chain reaction (PCR) analysis of the gene content of the reverse paint in order to provide a more detailed analysis of cytogenetic abnormalities in canine tumors. We examine two fibrosarcomas, both from female Labrador retrievers, and show abnormalities in chromosomes 11 and 30 in both cases. Evidence of involvement of TGFBR1 is presented for one tumor.

  12. Cutaneous paragonimiasis due to triploid Paragonimus westermani presenting as a non-migratory subcutaneous nodule: a case report

    PubMed Central

    2014-01-01

    Introduction Paragonimiasis is a food-borne infection caused by Paragonimus parasites. The lungs and pleura are the primary sites for the infection; however, ectopic infection can occur in other organs such as skin, liver and brain. It is difficult to make a diagnosis of ectopic paragonimiasis due to an ignorance of, and unfamiliarity with the disease. We report the case of a patient with subcutaneous paragonimiasis diagnosed by histopathological analysis and serological testing. Case presentation A 39-year-old Chinese immigrant woman presented with a subcutaneous nodule in her left lower back. The nodule was initially suspected of lipoma and she was followed up on without any treatment. However, it gradually indurated and the nodule was resected surgically. A magnetic resonance imaging scan revealed a polycystic lesion with inhomogeneous low or high intensity on T1- or T2-weighted images, respectively. The rim of the lesion was enhanced after contrast enhancement, but the inside did not show high-signal intensity. A histological analysis of the surgically resected specimen revealed variable-sized tubulo-cystic structures. The cyst wall showed a granulomatous change with scant eosinophilic infiltration. A number of parasite ova were observed in the necrotic tissue inside the cysts, and a parasite body with a presumed oral sucker and reproductive organ was also detected, suggesting a trematode infection. A subsequent serological examination showed a positive reaction of her serum to the Paragonimus westermani antigen. No abnormal findings were found on her chest computed tomography scan. The diagnosis of subcutaneous paragonimiasis caused by Paragonimus westermani was made. Conclusions We report a case presenting only as a non-migratory subcutaneous nodule without any pleuropulmonary lesion, which was initially suspected of lipoma but denied by magnetic resonance imaging scan results. The case was subsequently diagnosed as subcutaneous paragonimiasis from the results of histopathological analysis and serological testing. PMID:25322860

  13. A double sealing technique for increasing the precision of headspace-gas chromatographic analysis.

    PubMed

    Xie, Wei-Qi; Yu, Kong-Xian; Gong, Yi-Xian

    2018-01-19

    This paper investigates a new double sealing technique for increasing the precision of the headspace gas chromatographic method. The air leakage problem caused by the high pressure in the headspace vial during the headspace sampling process has a great impact to the measurement precision in the conventional headspace analysis (i.e., single sealing technique). The results (using ethanol solution as the model sample) show that the present technique is effective to minimize such a problem. The double sealing technique has an excellent measurement precision (RSD < 0.15%) and accuracy (recovery = 99.1%-100.6%) for the ethanol quantification. The detection precision of the present method was 10-20 times higher than that in earlier HS-GC work that use conventional single sealing technique. The present double sealing technique may open up a new avenue, and also serve as a general strategy for improving the performance (i.e., accuracy and precision) of headspace analysis of various volatile compounds. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Stress analysis of rotating propellers subject to forced excitations

    NASA Astrophysics Data System (ADS)

    Akgun, Ulas

    Turbine blades experience vibrations due to the flow disturbances. These vibrations are the leading cause for fatigue failure in turbine blades. This thesis presents the finite element analysis methods to estimate the maximum vibrational stresses of rotating structures under forced excitation. The presentation included starts with the derived equations of motion for vibration of rotating beams using energy methods under the Euler Bernoulli beam assumptions. The nonlinear large displacement formulation captures the centrifugal stiffening and gyroscopic effects. The weak form of the equations and their finite element discretization are shown. The methods implemented were used for normal modes analyses and forced vibration analyses of rotating beam structures. The prediction of peak stresses under simultaneous multi-mode excitation show that the maximum vibrational stresses estimated using the linear superposition of the stresses can greatly overestimate the stresses if the phase information due to damping (physical and gyroscopic effects) are neglected. The last section of this thesis also presents the results of a practical study that involves finite element analysis and redesign of a composite propeller.

  15. Floral Biosynthesis of Mn3O4 and Fe2O3 Nanoparticles Using Chaenomeles sp. Flower Extracts for Efficient Medicinal Applications

    NASA Astrophysics Data System (ADS)

    Karunakaran, Gopalu; Jagathambal, Matheswaran; Kolesnikov, Evgeny; Dmitry, Arkhipov; Ishteev, Artur; Gusev, Alexander; Kuznetsov, Denis

    2017-08-01

    Manganese oxide (Mn3O4) and iron oxide (Fe2O3) nanoparticles were successfully synthesized with the flower extracts of Chaenomeles sp. This is the first ever approach to synthesize nanoparticles from Chaenomeles sp. flower extracts. The organic molecules present in the flower extracts actively converted the nitrate precursor into its corresponding nanoparticles. The organic molecules that are involved in the synthesis of nanoparticles are identified using different phytochemical and gas chromatography-mass spectrometry analyses. The identified components are glycosides, alkaloids, terpenoids, saponins, flavonoids, quinines, and steroids. The structural and chemical compositions of the synthesized powder were also analyzed. The x-ray powder diffraction analysis revealed that the particles show tetragonal and rhombohedral crystalline phases. The Fourier transform infrared spectroscopy analysis showed the functional groups that are involved in the reduction of nitrates into the corresponding nanoparticles. Energy-dispersive x-ray spectroscopy analysis confirmed the presence of the elements in the synthesized nanoparticles. Transmission electron microscopy images showed the formation of spherical nanoparticles with an average size of 30-100 nm. Antioxidant analysis showed that the synthesized nanoparticles had excellent antioxidant potential. The antibacterial study showed that they inhibit the growth of harmful bacteria such as Pseudomonas aeruginosa and Streptococcus pyogenes. Thus, this study proposes a new eco-friendly and nontoxic method to synthesize nanoparticles for medicinal applications.

  16. Fully automatic and precise data analysis developed for time-of-flight mass spectrometry.

    PubMed

    Meyer, Stefan; Riedo, Andreas; Neuland, Maike B; Tulej, Marek; Wurz, Peter

    2017-09-01

    Scientific objectives of current and future space missions are focused on the investigation of the origin and evolution of the solar system with the particular emphasis on habitability and signatures of past and present life. For in situ measurements of the chemical composition of solid samples on planetary surfaces, the neutral atmospheric gas and the thermal plasma of planetary atmospheres, the application of mass spectrometers making use of time-of-flight mass analysers is a technique widely used. However, such investigations imply measurements with good statistics and, thus, a large amount of data to be analysed. Therefore, faster and especially robust automated data analysis with enhanced accuracy is required. In this contribution, an automatic data analysis software, which allows fast and precise quantitative data analysis of time-of-flight mass spectrometric data, is presented and discussed in detail. A crucial part of this software is a robust and fast peak finding algorithm with a consecutive numerical integration method allowing precise data analysis. We tested our analysis software with data from different time-of-flight mass spectrometers and different measurement campaigns thereof. The quantitative analysis of isotopes, using automatic data analysis, yields results with an accuracy of isotope ratios up to 100 ppm for a signal-to-noise ratio (SNR) of 10 4 . We show that the accuracy of isotope ratios is in fact proportional to SNR -1 . Furthermore, we observe that the accuracy of isotope ratios is inversely proportional to the mass resolution. Additionally, we show that the accuracy of isotope ratios is depending on the sample width T s by T s 0.5 . Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  17. PROBING THE DEEP END OF THE MILKY WAY WITH KEPLER : ASTEROSEISMIC ANALYSIS OF 854 FAINT RED GIANTS MISCLASSIFIED AS COOL DWARFS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mathur, S.; García, R. A.; Beck, P. G.

    Asteroseismology has proven to be an excellent tool to determine not only global stellar properties with good precision, but also to infer the stellar structure, dynamics, and evolution for a large sample of Kepler stars. Prior to the launch of the mission, the properties of Kepler targets were inferred from broadband photometry, leading to the Kepler Input Catalog (KIC). The KIC was later revised in the Kepler Star Properties Catalog, based on literature values and an asteroseismic analysis of stars that were unclassified in the KIC. Here, we present an asteroseismic analysis of 45,400 stars that were classified as dwarfsmore » in the Kepler Star Properties Catalog. We found that around 2% of the sample shows acoustic modes in the typical frequency range that put them in the red-giant category rather than the cool dwarf category. We analyze the asteroseismic properties of these stars, derive their surface gravities, masses, and radii, and present updated effective temperatures and distances. We show that the sample is significantly fainter than the previously known oscillating giants in the Kepler field, with the faintest stars reaching down to a Kepler magnitude of Kp ∼ 16. We demonstrate that 404 stars are at distances beyond 5 kpc and that the stars are significantly less massive than for the original Kepler red-giant sample, consistent with a population of distant halo giants. A comparison with a galactic population model shows that up to 40 stars might be genuine halo giants, which would increase the number of known asteroseismic halo stars by a factor of 4. The detections presented here will provide a valuable sample for galactic archeology studies.« less

  18. Severe weather as a spectacle: the Meteo-Show

    NASA Astrophysics Data System (ADS)

    Orbe, Iñaki; Gaztelumendi, Santiago

    2017-06-01

    In this work we focus on perhaps one of the worst journalist practice when dealing with severe weather, the Meteo-Show or the extended practice, especially in TV, for using weather and meteorology for spectacle. Journalism today has found weather information in a real goldmine in terms of audience due to the growing public interest in this matter. However, as it happens with other content, sensationalism and exaggeration have also reached weather information, primarily when episodes of adverse nature (snow, heavy rain, floods, etc.) are addressed. In this paper we look to identify the worst practices in weather communication through analysis of examples from real journalist work. We present some keys to understand this trend, highlighting the ingredients that are present in the worst Meteo-show.

  19. [Macrocephalic spermatozoa. What would be the impact on reproduction?].

    PubMed

    Guichaoua, M-R; Mercier, G; Geoffroy-Siraudin, C; Paulmyer-Lacroix, O; Lanteaume, A; Metzler-Guillemin, C; Perrin, J; Achard, V

    2009-09-01

    We want to highlight the risk of infertility and failure of Assisted Reproductive Technologies due to the presence of macrocephalic spermatozoa (MS) in the sperm at rate equalling or superior to 20% in at least one semen analysis. We did a retrospective analysis of 19 infertile patients presenting MS at average rate between 14.3 and 49.7%. For each patient, at least one semen analysis showed a MS rate equal or superior to 20%. We did an automated analysis of the spermatozoa surface for 13 patients and a detailed analysis of the MS morphology in 18 patients. Thirteen couples benefited of one or more IVF with or without ICSI. The semen analysis shows an impairment of one or more parameter of the sperm in all patients. Three morphological aspects for MS were highlighted: MS with irregular head, MS with regular head, and MS with multiple heads, with a dominance of irregular heads. The spermatozoa surface analysis shows a significant increase of the average surface and of the standard deviation (p<0.0001). The average rate of pregnancies by transfer is decreased compared to usual rates in our laboratories (13% versus 28%). We want to sensitize biologist and clinical doctors to the existence of partial forms of this syndrome, which could be related to infertility with impaired sperm parameters and low pregnancy rates after FIV or ICSI.

  20. Mechanisms governing brittle fault mechanics - a multi-scale study from the Permian Khao-Kwang fold-and-thrust belt, Thailand

    NASA Astrophysics Data System (ADS)

    von Hagke, Christoph; Morley, Chris; Kanitpanyacharoen, Waruntorn

    2017-04-01

    Despite our qualitative understanding of factors contributing to thrust and detachment weakness such as mineralogy, pore fluid pressure, or efficiency of structure localization, it is difficult to assess the contribution of the individual factors. Here we present multi-scale analysis of a mixed clay / carbonate high displacement (kms of heave) thrust zone, where it is possible to study structures formed within a similar temperature and pressure regime, and thus only varying due to lithological contrasts. We mapped the well-exposed thrust zone in a large quarry at outcrop scale in five separate sections present along a strike-distance of 1 km. The thrust zone shows considerable variations in structural style, as well as localization within different clay and limestone horizons. Zones of low and high strain have been identified. We investigate these changes in macroscopic deformation style using Virtual Polarizing Microscopy, and the combined methods of Broad Ion Beam milling and Scanning Electron Microscopy in addition with XRD analysis. We characterize structural and mineralogical variations in the thrust zone at all scales, from outcrop down to nano-meters. Results show strain localization is heterogeneous, with strong variations along strike. Within the clay package, strain localizes along zones rich in organic matter. Microstructures are complex, and show multiple deformation events, including crack-seal processes and reworking of vein material. Pressure solution is dominant. XRD analysis shows mineralogical differences between zones of high and low strain within the shale-dominated package. However, highest strain does not only occur in the clay units, but partly is accommodated in the surrounding limestone.

  1. Economic cycles and their synchronization: Spectral analysis of macroeconomic series from Italy, The Netherlands, and the UK

    NASA Astrophysics Data System (ADS)

    Sella, Lisa; Vivaldo, Gianna; Ghil, Michael; Groth, Andreas

    2010-05-01

    The present work applies several advanced spectral methods (Ghil et al., Rev. Geophys., 2002) to the analysis of macroeconomic fluctuations in Italy, The Netherlands, and the United Kingdom. These methods provide valuable time-and-frequency-domain tools that complement traditional time-domain analysis, and are thus fairly well known by now in the geosciences and life sciences, but not yet widespread in quantitative economics. In particular, they enable the identification and characterization of nonlinear trends and dominant cycles --- including low-frequency and seasonal components --- that characterize the behavior of each time series. We explore five fundamental indicators of the real (i.e., non-monetary), aggregate economy --- namely gross domestic product (GDP), consumption, fixed investments, exports and imports --- in a univariate as well as multivariate setting. A single-channel analysis by means of three independent spectral methods --- singular spectrum analysis (SSA), the multi-taper method (MTM), and the maximum-entropy method (MEM) --- reveals very similar near-annual cycles, as well as several longer periodicities, in the macroeconomic indicators of all the countries analyzed. Since each indicator represents different features of an economic system, we combine them to infer if common oscillatory modes are present, either among different indicators within the same country or among the same indicators across different countries. Multichannel-SSA (M-SSA) reinforces the previous results, and shows that the common modes agree in character with solutions of a non-equilibrium dynamic model (NEDyM) that produces endogenous business cycles (Hallegatte et al., JEBO, 2008). The presence of these modes in NEDyM results from adjustment delays and other nonequilibrium effects that were added to a neoclassical Solow (Q. J. Econ., 1956) growth model. Their confirmation by the present analysis has important consequences for the net impact of natural disasters on the economy of a country: Hallegatte and Ghil (Ecol. Econ., 2008) have shown that the presence of business cycles modifies substantially this impact with respect to their impact on an economy in or near equilibrium. The present work concludes with a study of the synchronization of economic fluctuations, which follows a similar study of macroeconomic indicators for the United States, presented in a nearby poster. Since business cycles are not country-specific phenomena, but show common characteristics across countries, our aim is to uncover hidden global behavior across the European economies (cf. Mazzi and Savio, Macmillan, 2006).

  2. An empirical examination of WISE/NEOWISE asteroid analysis and results

    NASA Astrophysics Data System (ADS)

    Myhrvold, Nathan

    2017-10-01

    Observations made by the WISE space telescope and subsequent analysis by the NEOWISE project represent the largest corpus of asteroid data to date, describing the diameter, albedo, and other properties of the ~164,000 asteroids in the collection. I present a critical reanalysis of the WISE observational data, and NEOWISE results published in numerous papers and in the JPL Planetary Data System (PDS). This analysis reveals shortcomings and a lack of clarity, both in the original analysis and in the presentation of results. The procedures used to generate NEOWISE results fall short of established thermal modelling standards. Rather than using a uniform protocol, 10 modelling methods were applied to 12 combinations of WISE band data. Over half the NEOWISE results are based on a single band of data. Most NEOWISE curve fits are poor quality, frequently missing many or all the data points. About 30% of the single-band results miss all the data; 43% of the results derived from the most common multiple-band combinations miss all the data in at least one band. The NEOWISE data processing procedures rely on inconsistent assumptions, and introduce bias by systematically discarding much of the original data. I show that error estimates for the WISE observational data have a true uncertainty factor of ~1.2 to 1.9 times larger than previously described, and that the error estimates do not fit a normal distribution. These issues call into question the validity of the NEOWISE Monte-Carlo error analysis. Comparing published NEOWISE diameters to published estimates using radar, occultation, or spacecraft measurements (ROS) reveals 150 for which the NEOWISE diameters were copied exactly from the ROS source. My findings show that the accuracy of diameter estimates for NEOWISE results depend heavily on the choice of data bands and model. Systematic errors in the diameter estimates are much larger than previously described. Systematic errors for diameters in the PDS range from -3% to +27%. Random errors range from -14% to +19% when using all four WISE bands, and from -45% to +74% in cases using only the W2 band. The results presented here show that much work remains to be done towards understanding asteroid data from WISE/NEOWISE.

  3. Repolarization of hepatocytes in culture.

    PubMed

    Talamini, M A; Kappus, B; Hubbard, A

    1997-01-01

    We have evaluated the biochemical, morphological, and functional redevelopment of polarity in freshly isolated hepatocytes cultured using a double layer collagen gel sandwich technique. Western blot analysis showed increased cellular levels of the cell adhesion protein uvomorulin as cultured hepatocytes repolarized. Immunofluorescence studies using antibodies against domain-specific membrane proteins showed polarity as early as 48 hours, although the pattern of the polymeric Immunoglobulin-A receptor (pIgA-R) differed from in vivo liver. Electron microscopy showed developing bile canaliculi at 1 day. However, the functional presence of tight junctions was absent at 1 day, but present at 5 days. We further showed functional polarity to be present at 4 days by documenting the ability of cultured hepatocytes to metabolize and excrete fluorescein diacetate into visible bile canaliculi. We conclude that hepatocytes cultured appropriately develop morphological and functional polarity. Hepatocyte culture is therefore a useful tool for the study of mechanisms responsible for the development of polarized function.

  4. Analysis of antibiotic multi-resistant bacteria and resistance genes in the effluent of an intensive shrimp farm (Long An, Vietnam).

    PubMed

    Pham, Thi Thu Hang; Rossi, Pierre; Dinh, Hoang Dang Khoa; Pham, Ngoc Tu Anh; Tran, Phuong Anh; Ho, To Thi Khai Mui; Dinh, Quoc Tuc; De Alencastro, Luiz Felippe

    2018-05-15

    In Vietnam, intensive shrimp farms heavily rely on a wide variety of antibiotics (ABs) to treat animals or prevent disease outbreak. Potential for the emergence of multi-resistant bacteria is high, with the concomitant contamination of adjacent natural aquatic habitats used for irrigation and drinking water, impairing in turn human health system. In the present study, quantification of AB multi-resistant bacteria was carried out in water and sediment samples from effluent channels connecting a shrimp farming area to the Vam Co River (Long An Province, Vietnam). Bacterial strains, e.g. Klebsiella pneumoniae and Aeromonas hydrophila, showing multi-resistance traits were isolated. Molecular biology analysis showed that these strains possessed from four to seven different AB resistance genes (ARGs) (e.g. sul1, sul2, qnrA, ermB, tetA, aac(6)lb, dfrA1, dfr12, dfrA5), conferring multidrug resistance capacity. Sequencing of plasmids present within these multi-resistant strains led to the identification of a total of forty-one resistance genes, targeting nine AB groups. qPCR analysis on the sul2 gene revealed the presence of high copy numbers in the effluent channel connecting to the Vam Co River. The results of the present study clearly indicated that multi-resistant bacteria present in intensive shrimp cultures may disseminate in the natural environment. This study offered a first insight in the impact of plasmid-born ARGs and the related pathogenic bacteria that could emerged due to inappropriate antibiotic utilization in South Vietnam. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. Abort-once-around entry dispersion corridor analysis. [for space shuttle reentry

    NASA Technical Reports Server (NTRS)

    Kyle, H. C.

    1975-01-01

    Abort-Once-Around (AOA) entry dispersion corridors were determined for Shuttle Mission 3A. These corridors are presented as plots of entry interface flight path angle versus range to target. The methods used to determine the corridors are discussed. Major dispersion sources are discussed and results presented. While specific trajectory inputs and constraints are subject to change, the dispersion corridors show the trends under consideration. The corridors presented show the delta V advantage of the two-burn over the one-burn AOA. The atmospheric dispersion study illustrates the need to target for the seasonal atmosphere. The 40 deg/30 deg angle of attack (alpha) (TPS design) profile did not provide adequate crossrange capability with worst case aerodynamic dispersions. This problem was alleviated with the change to a 38 deg/28 deg alpha profile. The backface temperatures calculated were generally higher than the present limits.

  6. An efficient descriptor model for designing materials for solar cells

    NASA Astrophysics Data System (ADS)

    Alharbi, Fahhad H.; Rashkeev, Sergey N.; El-Mellouhi, Fedwa; Lüthi, Hans P.; Tabet, Nouar; Kais, Sabre

    2015-11-01

    An efficient descriptor model for fast screening of potential materials for solar cell applications is presented. It works for both excitonic and non-excitonic solar cells materials, and in addition to the energy gap it includes the absorption spectrum (α(E)) of the material. The charge transport properties of the explored materials are modelled using the characteristic diffusion length (Ld) determined for the respective family of compounds. The presented model surpasses the widely used Scharber model developed for bulk heterojunction solar cells. Using published experimental data, we show that the presented model is more accurate in predicting the achievable efficiencies. To model both excitonic and non-excitonic systems, two different sets of parameters are used to account for the different modes of operation. The analysis of the presented descriptor model clearly shows the benefit of including α(E) and Ld in view of improved screening results.

  7. Development of advanced methods for analysis of experimental data in diffusion

    NASA Astrophysics Data System (ADS)

    Jaques, Alonso V.

    There are numerous experimental configurations and data analysis techniques for the characterization of diffusion phenomena. However, the mathematical methods for estimating diffusivities traditionally do not take into account the effects of experimental errors in the data, and often require smooth, noiseless data sets to perform the necessary analysis steps. The current methods used for data smoothing require strong assumptions which can introduce numerical "artifacts" into the data, affecting confidence in the estimated parameters. The Boltzmann-Matano method is used extensively in the determination of concentration - dependent diffusivities, D(C), in alloys. In the course of analyzing experimental data, numerical integrations and differentiations of the concentration profile are performed. These methods require smoothing of the data prior to analysis. We present here an approach to the Boltzmann-Matano method that is based on a regularization method to estimate a differentiation operation on the data, i.e., estimate the concentration gradient term, which is important in the analysis process for determining the diffusivity. This approach, therefore, has the potential to be less subjective, and in numerical simulations shows an increased accuracy in the estimated diffusion coefficients. We present a regression approach to estimate linear multicomponent diffusion coefficients that eliminates the need pre-treat or pre-condition the concentration profile. This approach fits the data to a functional form of the mathematical expression for the concentration profile, and allows us to determine the diffusivity matrix directly from the fitted parameters. Reformulation of the equation for the analytical solution is done in order to reduce the size of the problem and accelerate the convergence. The objective function for the regression can incorporate point estimations for error in the concentration, improving the statistical confidence in the estimated diffusivity matrix. Case studies are presented to demonstrate the reliability and the stability of the method. To the best of our knowledge there is no published analysis of the effects of experimental errors on the reliability of the estimates for the diffusivities. For the case of linear multicomponent diffusion, we analyze the effects of the instrument analytical spot size, positioning uncertainty, and concentration uncertainty on the resulting values of the diffusivities. These effects are studied using Monte Carlo method on simulated experimental data. Several useful scaling relationships were identified which allow more rigorous and quantitative estimates of the errors in the measured data, and are valuable for experimental design. To further analyze anomalous diffusion processes, where traditional diffusional transport equations do not hold, we explore the use of fractional calculus in analytically representing these processes is proposed. We use the fractional calculus approach for anomalous diffusion processes occurring through a finite plane sheet with one face held at a fixed concentration, the other held at zero, and the initial concentration within the sheet equal to zero. This problem is related to cases in nature where diffusion is enhanced relative to the classical process, and the order of differentiation is not necessarily a second--order differential equation. That is, differentiation is of fractional order alpha, where 1 ≤ alpha < 2. For alpha = 2, the presented solutions reduce to the classical second-order diffusion solution for the conditions studied. The solution obtained allows the analysis of permeation experiments. Frequently, hydrogen diffusion is analyzed using electrochemical permeation methods using the traditional, Fickian-based theory. Experimental evidence shows the latter analytical approach is not always appropiate, because reported data shows qualitative (and quantitative) deviation from its theoretical scaling predictions. Preliminary analysis of data shows better agreement with fractional diffusion analysis when compared to traditional square-root scaling. Although there is a large amount of work in the estimation of the diffusivity from experimental data, reported studies typically present only the analytical description for the diffusivity, without scattering. However, because these studies do not consider effects produced by instrument analysis, their direct applicability is limited. We propose alternatives to address these, and to evaluate their influence on the final resulting diffusivity values.

  8. NASCOM network: Ground communications reliability report

    NASA Technical Reports Server (NTRS)

    1973-01-01

    A reliability performance analysis of the NASCOM Network circuits is reported. Network performance narrative summary is presented to include significant changes in circuit configurations, current figures, and trends in each trouble category with notable circuit totals specified. Lost time and interruption tables listing circuits which were affected by outages showing their totals category are submitted. A special analysis of circuits with low reliabilities is developed with tables depicting the performance and graphs for individual reliabilities.

  9. Metrics for Analyzing Quantifiable Differentiation of Designs with Varying Integrity for Hardware Assurance

    DTIC Science & Technology

    2017-03-01

    proposed. Expected profiles can incorporate a level of overdesign. Finally, the Design Integrity measuring techniques are applied to five Test Article ...Inserted into Test System Table 2 presents the results of the analysis applied to each of the test article designs. Each of the domains are...the lowest integrities. Based on the analysis, the DI metric shows measurable differentiation between all five Test Article Error Location Error

  10. A METHOD FOR AUTOMATED ANALYSIS OF 10 ML WATER SAMPLES CONTAINING ACIDIC, BASIC, AND NEUTRAL SEMIVOLATILE COMPOUNDS LISTED IN USEPA METHOD 8270 BY SOLID PHASE EXTRACTION COUPLED IN-LINE TO LARGE VOLUME INJECTION GAS CHROMATOGRAPHY/MASS SPECTROMETRY

    EPA Science Inventory

    Data is presented showing the progress made towards the development of a new automated system combining solid phase extraction (SPE) with gas chromatography/mass spectrometry for the single run analysis of water samples containing a broad range of acid, base and neutral compounds...

  11. Investigating cardiorespiratory interaction by cross-spectral analysis of event series

    NASA Astrophysics Data System (ADS)

    Schäfer, Carsten; Rosenblum, Michael G.; Pikovsky, Arkady S.; Kurths, Jürgen

    2000-02-01

    The human cardiovascular and respiratory systems interact with each other and show effects of modulation and synchronization. Here we present a cross-spectral technique that specifically considers the event-like character of the heartbeat and avoids typical restrictions of other spectral methods. Using models as well as experimental data, we demonstrate how modulation and synchronization can be distinguished. Finally, we compare the method to traditional techniques and to the analysis of instantaneous phases.

  12. The Correlation of Active and Passive Microwave Outputs for the Skylab S-193 Sensor

    NASA Technical Reports Server (NTRS)

    Krishen, K.

    1976-01-01

    This paper presents the results of the correlation analysis of the Skylab S-193 13.9 GHz Radiometer/Scatterometer data. Computer analysis of the S-193 data shows more than 50 percent of the radiometer and scatterometer data are uncorrelated. The correlation coefficients computed for the data gathered over various ground scenes indicates the desirability of using both active and passive sensors for the determination of various Earth phenomena.

  13. Analysis of Energy Consumption for Ad Hoc Wireless Sensor Networks Using a Bit-Meter-per-Joule Metric

    NASA Astrophysics Data System (ADS)

    Gao, J. L.

    2002-04-01

    In this article, we present a system-level characterization of the energy consumption for sensor network application scenarios. We compute a power efficiency metric -- average watt-per-meter -- for each radio transmission and extend this local metric to find the global energy consumption. This analysis shows how overall energy consumption varies with transceiver characteristics, node density, data traffic distribution, and base-station location.

  14. A visual analysis of multi-attribute data using pixel matrix displays

    NASA Astrophysics Data System (ADS)

    Hao, Ming C.; Dayal, Umeshwar; Keim, Daniel; Schreck, Tobias

    2007-01-01

    Charts and tables are commonly used to visually analyze data. These graphics are simple and easy to understand, but charts show only highly aggregated data and present only a limited number of data values while tables often show too many data values. As a consequence, these graphics may either lose or obscure important information, so different techniques are required to monitor complex datasets. Users need more powerful visualization techniques to digest and compare detailed multi-attribute data to analyze the health of their business. This paper proposes an innovative solution based on the use of pixel-matrix displays to represent transaction-level information. With pixelmatrices, users can visualize areas of importance at a glance, a capability not provided by common charting techniques. We present our solutions to use colored pixel-matrices in (1) charts for visualizing data patterns and discovering exceptions, (2) tables for visualizing correlations and finding root-causes, and (3) time series for visualizing the evolution of long-running transactions. The solutions have been applied with success to product sales, Internet network performance analysis, and service contract applications demonstrating the benefits of our method over conventional graphics. The method is especially useful when detailed information is a key part of the analysis.

  15. Reliability analysis of component-level redundant topologies for solid-state fault current limiter

    NASA Astrophysics Data System (ADS)

    Farhadi, Masoud; Abapour, Mehdi; Mohammadi-Ivatloo, Behnam

    2018-04-01

    Experience shows that semiconductor switches in power electronics systems are the most vulnerable components. One of the most common ways to solve this reliability challenge is component-level redundant design. There are four possible configurations for the redundant design in component level. This article presents a comparative reliability analysis between different component-level redundant designs for solid-state fault current limiter. The aim of the proposed analysis is to determine the more reliable component-level redundant configuration. The mean time to failure (MTTF) is used as the reliability parameter. Considering both fault types (open circuit and short circuit), the MTTFs of different configurations are calculated. It is demonstrated that more reliable configuration depends on the junction temperature of the semiconductor switches in the steady state. That junction temperature is a function of (i) ambient temperature, (ii) power loss of the semiconductor switch and (iii) thermal resistance of heat sink. Also, results' sensitivity to each parameter is investigated. The results show that in different conditions, various configurations have higher reliability. The experimental results are presented to clarify the theory and feasibility of the proposed approaches. At last, levelised costs of different configurations are analysed for a fair comparison.

  16. [Screening and identification of low temperature-adapted antagonistic Bacillus isolated from Kekexili region of West China and the analysis of the isolates lipopeptide compounds].

    PubMed

    Xie, Yong-Li; Gao, Xue-Wen

    2013-01-01

    The research and exploitation of special microbial resources in extreme environment is of scientific significance and has broad applied prospect. In this paper, eight Bacillus strains isolated from the vegetation rhizospheres in Kekexili extreme region of Qinghai Province and presented good growth status at low temperature 4 and 10 degrees C were identified. Through physiological and biochemical analysis, rep-PCR fingerprinting, and 16S rDNA and gyrB partial sequence analyses, the eight strains were identified as Bacillus mojavensis (3 isolates), Bacillus amyloliquefaciens (1 isolate), and Bacillus simplex (4 isolates). The agar plate antagonistic test showed that four of the isolates presented distinct antagonistic activity to Sclerotinia sclerotiorum and Xanthomonas oryzae pv. oryzae. The MALDI-TOF-MS analysis showed that the strain KKD1 (B. mojavensis) produced fengycin and surfactin, whereas the strain KKD2 (B. amyloliquefaciens) produced iturin A, surfactin and fengycin, suggesting that the bio-control efficacy of the Bacillus strains could be related to the synthesis and excretion of the antifungal lipopeptide compounds. This study provided the bacterial resources for the research and exploitation of low temperature-adapted Bacillus bio-fertilizers and bio-pesticides.

  17. An insight into nutritional profile of selected Pleurotus species.

    PubMed

    Irshad, A; Sharif, S; Riaz, M; Anjum, F

    2018-01-01

    The global demand for good quality food indicates that consumers are more concerned about a particular diet associated with good health and lower risk for certain ailments. Mushrooms are widely used as healthy nutritious food. In the present study, the nutritional composition of four different Pleurotus sp. was determined. Prior to extraction, all the selected mushrooms were subjected for proximate composition analysis. The protein, fat, ash, total carbohydrate, fiber and energy contents were in the range of (16.07- 25.15%), (0.64-2.02%), (2.1-9.14%), (65.66-82.47%), (6.21-54.12%) and (342.20-394.30Kcal/100g), respectively. The spectrophotometric analysis showed that the concentration of protein was in the range of 45.78-33.47 mg/g in all Pleurotus sp. High performance liquid chromatographic analysis of sugars showed six different mono and disaccharides in all the selected mushrooms. The fatty acid profile by gas chromatography-mass spectrometry revealed that the main fatty acids in selected mushrooms were present in the order linoliec acid> oleic acid> palmitic acid. The results suggested that all the Pleurotus sp. could be considered as a rich source of nutrients.

  18. Discovery of cyanophage genomes which contain mitochondrial DNA polymerase.

    PubMed

    Chan, Yi-Wah; Mohr, Remus; Millard, Andrew D; Holmes, Antony B; Larkum, Anthony W; Whitworth, Anna L; Mann, Nicholas H; Scanlan, David J; Hess, Wolfgang R; Clokie, Martha R J

    2011-08-01

    DNA polymerase γ is a family A DNA polymerase responsible for the replication of mitochondrial DNA in eukaryotes. The origins of DNA polymerase γ have remained elusive because it is not present in any known bacterium, though it has been hypothesized that mitochondria may have inherited the enzyme by phage-mediated nonorthologous displacement. Here, we present an analysis of two full-length homologues of this gene, which were found in the genomes of two bacteriophages, which infect the chlorophyll-d containing cyanobacterium Acaryochloris marina. Phylogenetic analyses of these phage DNA polymerase γ proteins show that they branch deeply within the DNA polymerase γ clade and therefore share a common origin with their eukaryotic homologues. We also found homologues of these phage polymerases in the environmental Community Cyberinfrastructure for Advanced Microbial Ecology Research and Analysis (CAMERA) database, which fell in the same clade. An analysis of the CAMERA assemblies containing the environmental homologues together with the filter fraction metadata indicated some of these assemblies may be of bacterial origin. We also show that the phage-encoded DNA polymerase γ is highly transcribed as the phage genomes are replicated. These findings provide data that may assist in reconstructing the evolution of mitochondria.

  19. Applying traditional signal processing techniques to social media exploitation for situational understanding

    NASA Astrophysics Data System (ADS)

    Abdelzaher, Tarek; Roy, Heather; Wang, Shiguang; Giridhar, Prasanna; Al Amin, Md. Tanvir; Bowman, Elizabeth K.; Kolodny, Michael A.

    2016-05-01

    Signal processing techniques such as filtering, detection, estimation and frequency domain analysis have long been applied to extract information from noisy sensor data. This paper describes the exploitation of these signal processing techniques to extract information from social networks, such as Twitter and Instagram. Specifically, we view social networks as noisy sensors that report events in the physical world. We then present a data processing stack for detection, localization, tracking, and veracity analysis of reported events using social network data. We show using a controlled experiment that the behavior of social sources as information relays varies dramatically depending on context. In benign contexts, there is general agreement on events, whereas in conflict scenarios, a significant amount of collective filtering is introduced by conflicted groups, creating a large data distortion. We describe signal processing techniques that mitigate such distortion, resulting in meaningful approximations of actual ground truth, given noisy reported observations. Finally, we briefly present an implementation of the aforementioned social network data processing stack in a sensor network analysis toolkit, called Apollo. Experiences with Apollo show that our techniques are successful at identifying and tracking credible events in the physical world.

  20. Plant interspecies competition for sunlight: a mathematical model of canopy partitioning.

    PubMed

    Nevai, Andrew L; Vance, Richard R

    2007-07-01

    We examine the influence of canopy partitioning on the outcome of competition between two plant species that interact only by mutually shading each other. This analysis is based on a Kolmogorov-type canopy partitioning model for plant species with clonal growth form and fixed vertical leaf profiles (Vance and Nevai in J. Theor. Biol., 2007, to appear). We show that canopy partitioning is necessary for the stable coexistence of the two competing plant species. We also use implicit methods to show that, under certain conditions, the species' nullclines can intersect at most once. We use nullcline endpoint analysis to show that when the nullclines do intersect, and in such a way that they cross, then the resulting equilibrium point is always stable. We also construct surfaces that divide parameter space into regions within which the various outcomes of competition occur, and then study parameter dependence in the locations of these surfaces. The analysis presented here and in a companion paper (Nevai and Vance, The role of leaf height in plant competition for sunlight: analysis of a canopy partitioning model, in review) together shows that canopy partitioning is both necessary and, under appropriate parameter values, sufficient for the stable coexistence of two hypothetical plant species whose structure and growth are described by our model.

  1. An evaluation of interrupted and uninterrupted measurement of vocal stereotypy on perceived treatment outcomes.

    PubMed

    Carroll, Regina A; Kodak, Tiffany

    2014-01-01

    The type of procedure used to measure a target behavior may directly influence the perceived treatment outcomes. In the present study, we examined the influence of different data-analysis procedures on the outcomes of two commonly used treatments on the vocal stereotypy of 2 children with an autism spectrum disorder. In Study 1, we compared an interrupted and uninterrupted data-analysis procedure to measure vocal stereotypy during the implementation of response interruption and redirection (RIRD). The results showed that the interrupted data-analysis procedure overestimated the effectiveness of RIRD. In Study 2, we examined the influence of different data-analysis procedures on the interpretation of the relative effects of 2 different treatments for vocal stereotypy. Specifically, we compared interrupted and uninterrupted data-analysis procedures during the implementation of RIRD and noncontingent reinforcement (NCR) as a treatment for vocal stereotypy. The results showed that, as in Study 1, the interrupted data-analysis procedure overestimated the effectiveness of RIRD; however, this effect was not apparent with NCR. These findings suggest that different types of data analysis can influence the perceived success of a treatment. © Society for the Experimental Analysis of Behavior.

  2. Digit ratio (2D:4D) and male facial attractiveness: new data and a meta-analysis.

    PubMed

    Hönekopp, Johannes

    2013-10-01

    Digit ratio (2D:4D) appears to correlate negatively with prenatal testosterone (T) effects in humans. As T probably increases facial masculinity, which in turn might be positively related to male facial attractiveness, a number of studies have looked into the relationship between 2D:4D and male facial attractiveness, showing equivocal results. Here, I present the largest and third largest samples so far, which investigate the relationship between 2D:4D and male facial attractiveness in adolescents (n = 115) and young men (n = 80). I then present random-effects meta-analyses of the available data (seven to eight samples, overall n = 362 to 469). These showed small (r ≈ -.09), statistically non-significant relationships between 2D:4D measures and male facial attractiveness. Thus, 2D:4D studies offer no convincing evidence at present that prenatal T has a positive effect on male facial attractiveness. However, a consideration of confidence intervals shows that, at present, a theoretically meaningful relationship between 2D:4D and male facial attractiveness cannot be ruled out either.

  3. A Model and Simple Iterative Algorithm for Redundancy Analysis.

    ERIC Educational Resources Information Center

    Fornell, Claes; And Others

    1988-01-01

    This paper shows that redundancy maximization with J. K. Johansson's extension can be accomplished via a simple iterative algorithm based on H. Wold's Partial Least Squares. The model and the iterative algorithm for the least squares approach to redundancy maximization are presented. (TJH)

  4. Learning in a Changing Environment

    ERIC Educational Resources Information Center

    Speekenbrink, Maarten; Shanks, David R.

    2010-01-01

    Multiple cue probability learning studies have typically focused on stationary environments. We present 3 experiments investigating learning in changing environments. A fine-grained analysis of the learning dynamics shows that participants were responsive to both abrupt and gradual changes in cue-outcome relations. We found no evidence that…

  5. Present-Day Influence of English on Swedish as Found in Swedish Job Advertisements.

    ERIC Educational Resources Information Center

    Larson, Ben E.

    1990-01-01

    A brief analysis of job advertisements in Swedish newspapers notes the increasing trend toward the use of English rather than Swedish words for certain terms, attributing such use to the wish to show an international labor perspective. (five references) (CB)

  6. DISTRIBUTION SYSTEMS AS CONTAMINATION RESERVOIRS: IS A NEW PARADIGM NEEDED FOR TREATMENT AND MONITORING?

    EPA Science Inventory

    This presentation provides a review of numerous drinking water and geochemical investigations and recent studies of pipe deposits and water treatment materials. This analysis shows that there is growing evidence that many regulated drinking water constituents are not conservativ...

  7. Fully automated registration of first-pass myocardial perfusion MRI using independent component analysis.

    PubMed

    Milles, J; van der Geest, R J; Jerosch-Herold, M; Reiber, J H C; Lelieveldt, B P F

    2007-01-01

    This paper presents a novel method for registration of cardiac perfusion MRI. The presented method successfully corrects for breathing motion without any manual interaction using Independent Component Analysis to extract physiologically relevant features together with their time-intensity behavior. A time-varying reference image mimicking intensity changes in the data of interest is computed based on the results of ICA, and used to compute the displacement caused by breathing for each frame. Qualitative and quantitative validation of the method is carried out using 46 clinical quality, short-axis, perfusion MR datasets comprising 100 images each. Validation experiments showed a reduction of the average LV motion from 1.26+/-0.87 to 0.64+/-0.46 pixels. Time-intensity curves are also improved after registration with an average error reduced from 2.65+/-7.89% to 0.87+/-3.88% between registered data and manual gold standard. We conclude that this fully automatic ICA-based method shows an excellent accuracy, robustness and computation speed, adequate for use in a clinical environment.

  8. Integration of chemical and biological treatments for textile industry wastewater: a possible zero-discharge system.

    PubMed

    Lee, H H; Chen, G; Yue, P L

    2001-01-01

    Theoretical and experimental studies have established that integrated treatment systems (mostly chemical and biological) for various industrial wastewaters can achieve better quality of treatment and can be cost-effective. In the present study, the objective is to minimize the use of process water in the textile industry by an economical recycle and reuse scheme. The textile wastewater was first characterized in terms of COD, BOD5, salinity and color. In order to recycle such wastewater, the contaminants should be mineralized and/or removed according to the reusable textile water quality standards. Typical results show that this is achievable. An economic analysis has been conducted on the proposed integrated system. The economic analysis shows that the integrated system is economically more attractive than any of the single treatment technologies for achieving the same target of treatment. The information presented in this paper provides a feasible option for the reduction of effluent discharges in the textile industry.

  9. Penetrating abdominal gunshot wounds caused by high-velocity missiles: a review of 51 military injuries managed at a level-3 trauma center.

    PubMed

    Gorgulu, Semih; Gencosmanoglu, Rasim; Akaoglu, Cuneyt

    2008-01-01

    The aim of this study was to present the outcomes of military penetrating abdominal gunshot injuries, to identify factors that predict morbidity, and to compare the present results with those from two civilian trauma centers. Fifty-one consecutive patients who had suffered high-velocity gunshot wounds to the abdomen were assessed retrospectively. Penetrating abdominal trauma index, the number of injured organs, and the presence of colonic injury were significantly associated with high morbidity by univariate analysis. Multivariate analysis showed that only the number of organs injured and presence of colonic injury were independent predictors of morbidity. Our results showed that military rifle bullets do not cause greater tissue disruption than that found in wounds created by lower-velocity projectiles. The presence of colonic injury and the number of organs injured (more than three) seem to be important predictors of morbidity in penetrating abdominal gunshot wounds caused by high-velocity missiles.

  10. [Autoimmune lymphoproliferative syndrome].

    PubMed

    Rodrigues, Vera; Conde, Marta; Figueiredo, António; Vasconcelos, Júlia; Dias, Alexandra

    2011-01-01

    The Autoimmune Lymphoproliferative Syndrome (ALPS) is an impairment of lymphocyte apoptosis expressed by generalized non-malignant lymphoproliferation, lymphadenopathy and/or splenomegaly. This article describes a seven and 14 year old males. The first one was admitted at 3 years of age with fever, bicytopenia and generalized lymphadenopathy. Hystopathological analysis of lymph nodes showed reactive follicular hyperplasia and marked paracortical expansion. He was readmitted three years later presenting herpes zoster and similar clinical features. High levels of IL-10 and increasing tendency of Fas-L in plasma and serum. The second child was admitted at 13 years of age presenting thigh and gluteus cellulitis, anemia and neutropenia. T lymphocytes aß+CD4-CD8- 3,1%. Hystopathological analysis of lymph nodes showed marked paracortical hyperplasia. Both children are treated with mycophenolate mofetil with good response. ALPS is an underestimated entity that must be considered in non malign lymphoproliferation, autoimmunity and expansion of an unusual population of a/ßCD3+CD4-CD8-(double-negative T cells>1%).

  11. Elastic Instability of Slender Rods in Steady Shear Flow Yields Positive First Normal Stress Differences

    NASA Astrophysics Data System (ADS)

    Becker, Leif E.; Shelley, Michael J.

    2000-11-01

    First normal stress differences in shear flow are a fundamental property of Non-Newtonian fluids. Experiments involving dilute suspensions of slender fibers exhibit a sharp transition to non-zero normal stress differences beyond a critical shear rate, but existing continuum theories for rigid rods predict neither this transition nor the corresponding magnitude of this effect. We present the first conclusive evidence that elastic instabilities are predominantly responsible for observed deviations from the dilute suspension theory of rigid rods. Our analysis is based on slender body theory and the equilibrium equations of elastica. A straight slender body executing its Jeffery orbit in Couette flow is subject to axial fluid forcing, alternating between compression and tension. We present a stability analysis showing that elastic instabilities are possible for strong flows. Simulations give the fully non-linear evolution of this shape instability, and show that flexibility of the fibers alone is sufficient to cause both shear-thinning and significant first normal stress differences.

  12. Inverse problems in heterogeneous and fractured media using peridynamics

    DOE PAGES

    Turner, Daniel Z.; van Bloemen Waanders, Bart G.; Parks, Michael L.

    2015-12-10

    The following work presents an adjoint-based methodology for solving inverse problems in heterogeneous and fractured media using state-based peridynamics. We show that the inner product involving the peridynamic operators is self-adjoint. The proposed method is illustrated for several numerical examples with constant and spatially varying material parameters as well as in the context of fractures. We also present a framework for obtaining material parameters by integrating digital image correlation (DIC) with inverse analysis. This framework is demonstrated by evaluating the bulk and shear moduli for a sample of nuclear graphite using digital photographs taken during the experiment. The resulting measuredmore » values correspond well with other results reported in the literature. Lastly, we show that this framework can be used to determine the load state given observed measurements of a crack opening. Furthermore, this type of analysis has many applications in characterizing subsurface stress-state conditions given fracture patterns in cores of geologic material.« less

  13. Spatial fingerprints of community structure in human interaction network for an extensive set of large-scale regions.

    PubMed

    Kallus, Zsófia; Barankai, Norbert; Szüle, János; Vattay, Gábor

    2015-01-01

    Human interaction networks inferred from country-wide telephone activity recordings were recently used to redraw political maps by projecting their topological partitions into geographical space. The results showed remarkable spatial cohesiveness of the network communities and a significant overlap between the redrawn and the administrative borders. Here we present a similar analysis based on one of the most popular online social networks represented by the ties between more than 5.8 million of its geo-located users. The worldwide coverage of their measured activity allowed us to analyze the large-scale regional subgraphs of entire continents and an extensive set of examples for single countries. We present results for North and South America, Europe and Asia. In our analysis we used the well-established method of modularity clustering after an aggregation of the individual links into a weighted graph connecting equal-area geographical pixels. Our results show fingerprints of both of the opposing forces of dividing local conflicts and of uniting cross-cultural trends of globalization.

  14. Chemical evolution via beta decay: a case study in strontium-90

    NASA Astrophysics Data System (ADS)

    Marks, N. A.; Carter, D. J.; Sassi, M.; Rohl, A. L.; Sickafus, K. E.; Uberuaga, B. P.; Stanek, C. R.

    2013-02-01

    Using 90Sr as a representative isotope, we present a framework for understanding beta decay within the solid state. We quantify three key physical and chemical principles, namely momentum-induced recoil during the decay event, defect creation due to physical displacement, and chemical evolution over time. A fourth effect, that of electronic excitation, is also discussed, but this is difficult to quantify and is strongly material dependent. The analysis is presented for the specific cases of SrTiO3 and SrH2. By comparing the recoil energy with available threshold displacement data we show that in many beta-decay situations defects such as Frenkel pairs will not be created during decay as the energy transfer is too low. This observation leads to the concept of chemical evolution over time, which we quantify using density functional theory. Using a combination of Bader analysis, phonon calculations and cohesive energy calculations, we show that beta decay leads to counter-intuitive behavior that has implications for nuclear waste storage and novel materials design.

  15. Chemical evolution via beta decay: a case study in strontium-90.

    PubMed

    Marks, N A; Carter, D J; Sassi, M; Rohl, A L; Sickafus, K E; Uberuaga, B P; Stanek, C R

    2013-02-13

    Using (90)Sr as a representative isotope, we present a framework for understanding beta decay within the solid state. We quantify three key physical and chemical principles, namely momentum-induced recoil during the decay event, defect creation due to physical displacement, and chemical evolution over time. A fourth effect, that of electronic excitation, is also discussed, but this is difficult to quantify and is strongly material dependent. The analysis is presented for the specific cases of SrTiO(3) and SrH(2). By comparing the recoil energy with available threshold displacement data we show that in many beta-decay situations defects such as Frenkel pairs will not be created during decay as the energy transfer is too low. This observation leads to the concept of chemical evolution over time, which we quantify using density functional theory. Using a combination of Bader analysis, phonon calculations and cohesive energy calculations, we show that beta decay leads to counter-intuitive behavior that has implications for nuclear waste storage and novel materials design.

  16. New polyelectrolyte complex from pectin/chitosan and montmorillonite clay.

    PubMed

    da Costa, Marcia Parente Melo; de Mello Ferreira, Ivana Lourenço; de Macedo Cruz, Mauricio Tavares

    2016-08-01

    A new nanocomposite hydrogel was prepared by forming a crosslinked hybrid polymer network based on chitosan and pectin in the presence of montmorillonite clay. The influence of clay concentration (0.5 and 2% wt) as well as polymer ratios (1:1, 1:2 and 2:1) was investigated carefully. The samples were characterized by different techniques: transmission and scanning electron microscopy, X-ray diffraction, thermogravimetric analysis, infrared spectroscopy, swelling degree and compression test. Most samples presented swelling degree above 1000%, which permits characterizing them as superabsorbent material. Images obtained by transmission electron microscopy showed the presence of clay nanoparticles into hydrogel. The hydrogels' morphological properties were evaluated by scanning electron microscope in high and low-vacuum. The micrographs showed that the samples presented porous. The incorporation of clay produced hydrogels with differentiated morphology. Thermogravimetric analysis results revealed that the incorporation of clay in the samples provided greater thermal stability to the hydrogels. The compression resistance also increased with addition of clay. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Recent HBT results in Au+Au and p+p collisions from PHENIX

    NASA Astrophysics Data System (ADS)

    PHENIX Collaboration; Glenn, Andrew; PHENIX Collaboration

    2009-11-01

    We present Hanbury-Brown Twiss measurements from the PHENIX experiment at RHIC for final results for charged kaon pairs from s=200 GeV Au+Au collisions and preliminary results for charged pion pairs from s=200 GeVp+p collisions. We find that for kaon pairs from Au+Au, each traditional 3D Gaussian radius shows approximately the same linear increase as a function of Npart1/3. An imaging analysis reveals a significant non-Gaussian tail for r≳10 fm. The presence of a tail for kaon pairs demonstrates that similar non-Gaussian tails observed in earlier pion measurements cannot be fully explained by decays of long-lived resonances. The preliminary analysis of pions from s=200 GeV p+p minimum biased collisions show correlations which are well suited to traditional 3D HBT radii extraction via the Bowler-Sinyukov method, and we present R, R, and R as a function of mean transverse pair mass.

  18. A Hypomorphic RAG1 Mutation Resulting in a Phenotype Resembling Common Variable Immunodeficiency

    PubMed Central

    Abolhassani, Hassan; Wang, Ning; Aghamohammadi, Asghar; Rezaei, Nima; Lee, Yu Nee; Frugoni, Francesco; Notrangelo, Luigi D.; Pan-Hammarström, Qiang; Hammarström, Lennart

    2014-01-01

    Background RAG1 deficiency presents a varied spectrum of combined immunodeficiency, ranging from a T−B−NK+type of disease to a T+B+NK+ phenotype. Objective To assess the genetic background of common variable immunodeficiency (CVID) patients. Methods A patient diagnosed with CVID, who was born in a consanguineous family and thus would be expected to show an autosomal recessive inheritance, was subjected to clinical evaluation, immunological assays, homozygosity gene mapping, exome sequencing, Sanger sequencing and functional analysis. Results The 14-year-old patient, who suffered from liver granuloma, extranodal marginal zone B cell lymphoma and autoimmune neutropenia, is presented with a clinical picture resembling CVID. Genetic analysis of this patient showed a homozygous hypomorphic RAG1 mutation (c.1073 G>A, p.C358Y) with a residual functional capacity of 48% of wild-type protein. Conclusion Our finding broadens the range of disorders associated with RAG1 mutations and may have important therapeutic implications. PMID:24996264

  19. Graphene-Based Liquid-Gated Field Effect Transistor for Biosensing: Theory and Experiments

    PubMed Central

    Reiner-Rozman, Ciril; Larisika, Melanie; Nowak, Christoph; Knoll, Wolfgang

    2015-01-01

    We present an experimental and theoretical characterization for reduced Graphene-Oxide (rGO) based FETs used for biosensing applications. The presented approach shows a complete result analysis and theoretically predictable electrical properties. The formulation was tested for the analysis of the device performance in the liquid gate mode of operation with variation of the ionic strength and pH-values of the electrolytes in contact with the FET. The dependence on the Debye length was confirmed experimentally and theoretically, utilizing the Debye length as a working parameter and thus defining the limits of applicability for the presented rGO-FETs. Furthermore, the FETs were tested for the sensing of biomolecules (bovine serum albumin (BSA) as reference) binding to gate-immobilized anti-BSA antibodies and analyzed using the Langmuir binding theory for the description of the equilibrium surface coverage as a function of the bulk (analyte) concentration. The obtained binding coefficients for BSA are found to be same as in results from literature, hence confirming the applicability of the devices. The FETs used in the experiments were fabricated using wet-chemically synthesized graphene, displaying high electron and hole mobility (μ) and provide the strong sensitivity also for low potential changes (by change of pH, ion concentration, or molecule adsorption). The binding coefficient for BSA-anti-BSA interaction shows a behavior corresponding to the Langmuir adsorption theory with a Limit of Detection (LOD) in the picomolar concentration range. The presented approach shows high reproducibility and sensitivity and a good agreement of the experimental results with the calculated data. PMID:25791463

  20. A thermoacoustic-Stirling heat engine: detailed study

    PubMed

    Backhaus; Swift

    2000-06-01

    A new type of thermoacoustic engine based on traveling waves and ideally reversible heat transfer is described. Measurements and analysis of its performance are presented. This new engine outperforms previous thermoacoustic engines, which are based on standing waves and intrinsically irreversible heat transfer, by more than 50%. At its most efficient operating point, it delivers 710 W of acoustic power to its resonator with a thermal efficiency of 0.30, corresponding to 41% of the Carnot efficiency. At its most powerful operating point, it delivers 890 W to its resonator with a thermal efficiency of 0.22. The efficiency of this engine can be degraded by two types of acoustic streaming. These are suppressed by appropriate tapering of crucial surfaces in the engine and by using additional nonlinearity to induce an opposing time-averaged pressure difference. Data are presented which show the nearly complete elimination of the streaming convective heat loads. Analysis of these and other irreversibilities show which components of the engine require further research to achieve higher efficiency. Additionally, these data show that the dynamics and acoustic power flows are well understood, but the details of the streaming suppression and associated heat convection are only qualitatively understood.

  1. Dietary supplementation with sorbitol results in selective enrichment of lactobacilli in rat intestine.

    PubMed

    Sarmiento-Rubiano, Luz Adriana; Zúñiga, Manuel; Pérez-Martínez, Gaspar; Yebra, María Jesús

    2007-01-01

    A potential prebiotic action has been ascribed to sorbitol, but in vivo evidence of this remains scarce. In the present work, the effect of sorbitol was compared to that of fructo-oligosaccharides (FOS) in a rat model. Microbiota changes, particularly in lactobacilli, were analyzed on fecal, colonic and cecal samples. Denaturing gradient gel electrophoresis (DGGE) analysis of 16S rRNA gene amplicons using universal primers showed that FOS and sorbitol diets exerted a strong influence upon gut microbiota patterns. When Lactobacillus group-specific primers were used, DGGE profiles revealed five DNA bands that belonged to Lactobacillus johnsonii, Lactobacillus sp. AD102, Lactobacillus intestinalis, Lactobacillus murinus and Lactobacillus reuteri. Although these species are present in all dietary groups, quantification by real-time PCR showed that sorbitol and FOS intake increased L. reuteri cell numbers, and sorbitol also contributed to maintaining the levels of Lactobacillus sp. AD102. Analysis of organic acid concentrations showed that sorbitol intake significantly increased colonic and cecal butyrate levels. Hence, sorbitol, which is widely used as a low-calorie sweetener, has the capacity, in our animal model, to modify gut microbiota activity in such a way as to possibly contribute to healthy colonic mucosa.

  2. Contingency learning without awareness: evidence for implicit control.

    PubMed

    Schmidt, James R; Crump, Matthew J C; Cheesman, Jim; Besner, Derek

    2007-06-01

    The results of four experiments provide evidence for controlled processing in the absence of awareness. Participants identified the colour of a neutral distracter word. Each of four words (e.g., MOVE) was presented in one of the four colours 75% of the time (Experiments 1 and 4) or 50% of the time (Experiments 2 and 3). Colour identification was faster when the words appeared in the colour they were most often presented in relative to when they appeared in another colour, even for participants who were subjectively unaware of any contingencies between the words and the colours. An analysis of sequence effects showed that participants who were unaware of the relation between distracter words and colours nonetheless controlled the impact of the word on performance depending on the nature of the previous trial. A block analysis of contingency-unaware participants revealed that contingencies were learned rapidly in the first block of trials. Experiment 3 showed that the contingency effect does not depend on the level of awareness, thus ruling out explicit strategy accounts. Finally, Experiment 4 showed that the contingency effect results from behavioural control and not from semantic association or stimulus familiarity. These results thus provide evidence for implicit control.

  3. The Morphometrical and Histopathological Changes which were Observed after Topical Ozone Therapy on an Exophytic Fibrous Gingival Lesion: A Case Report.

    PubMed

    Patel, Punit Vaibhav; Gujjari, Sheela Kumar

    2013-06-01

    We are presenting 2 cases where ozone therapy was used in the form of ozonated oil on an exophytic fibrous gingival lesion. A 42-years female patient was selected, who presented with a mild to moderately painful, exophytic, fibrous lesion on the upper anterior gingiva. This gingival lesion was treated with 2ml of ozonated oil, thrice daily for one week. After the ozone therapy, the postoperative outcomes were measured and analyzed. Finally, the lesion was subjected to an excisional biopsy and a histopathological evaluation. After the ozone therapy, the patient revealed that there was less pain. On examination of the lesion, an improvement was observed in the clinical sign of the inflammation and also a reduction in the surface ulceration. During the final biopsy, less bleeding was observed. The morphometrical analysis showed a reduction in the size of the lesion. The histopathological analysis showed a reduction in the collagen fibres and in the inflammatory cells in the connective tissue stroma. Topical ozone therapy provides potential benefits for the treatment of exophytic gingival lesions. The observed benefits in present case report needs to be verified in future with well-controlled clinical trials.

  4. Lunar Reconnaissance Orbiter Orbit Determination Accuracy Analysis

    NASA Technical Reports Server (NTRS)

    Slojkowski, Steven E.

    2014-01-01

    Results from operational OD produced by the NASA Goddard Flight Dynamics Facility for the LRO nominal and extended mission are presented. During the LRO nominal mission, when LRO flew in a low circular orbit, orbit determination requirements were met nearly 100% of the time. When the extended mission began, LRO returned to a more elliptical frozen orbit where gravity and other modeling errors caused numerous violations of mission accuracy requirements. Prediction accuracy is particularly challenged during periods when LRO is in full-Sun. A series of improvements to LRO orbit determination are presented, including implementation of new lunar gravity models, improved spacecraft solar radiation pressure modeling using a dynamic multi-plate area model, a shorter orbit determination arc length, and a constrained plane method for estimation. The analysis presented in this paper shows that updated lunar gravity models improved accuracy in the frozen orbit, and a multiplate dynamic area model improves prediction accuracy during full-Sun orbit periods. Implementation of a 36-hour tracking data arc and plane constraints during edge-on orbit geometry also provide benefits. A comparison of the operational solutions to precision orbit determination solutions shows agreement on a 100- to 250-meter level in definitive accuracy.

  5. Climatology of the scintillation onset over southern Brazil

    NASA Astrophysics Data System (ADS)

    Sousasantos, Jonas; de Oliveira Moraes, Alison; Sobral, José H. A.; Muella, Marcio T. A. H.; de Paula, Eurico R.; Paolini, Rafael S.

    2018-04-01

    This work presents an analysis of the climatology of the onset time of ionospheric scintillations at low latitude over the southern Brazilian territory near the peak of the equatorial ionization anomaly (EIA). Data from L1 frequency GPS receiver located in Cachoeira Paulista (22.4° S, 45.0° W; dip latitude 16.9° S), from September 1998 to November 2014, covering a period between solar cycles 23 and 24, were used in the present analysis of the scintillation onset time. The results show that the start time of the ionospheric scintillation follows a pattern, starting about 40 min earlier, in the months of November and December, when compared to January and February. The analyses presented here show that such temporal behavior seems to be associated with the ionospheric prereversal vertical drift (PRVD) magnitude and time. The influence of solar activity in the percentage of GPS links affected is also addressed together with the respective ionospheric prereversal vertical drift behavior. Based on this climatological study a set of empirical equations is proposed to be used for a GNSS alert about the scintillation prediction. The identification of this kind of pattern may support GNSS applications for aviation and oil extraction maritime stations positioning.

  6. Mean flow produced by small-amplitude vibrations of a liquid bridge with its free surface covered with an insoluble surfactant

    NASA Astrophysics Data System (ADS)

    Carrión, Luis M.; Herrada, Miguel A.; Montanero, José M.; Vega, José M.

    2017-09-01

    As is well known, confined fluid systems subject to forced vibrations produce mean flows, called in this context streaming flows. These mean flows promote an overall mass transport in the fluid that has consequences in the transport of passive scalars and surfactants, when these are present in a fluid interface. Such transport causes surfactant concentration inhomogeneities that are to be counterbalanced by Marangoni elasticity. Therefore, the interaction of streaming flows and Marangoni convection is expected to produce new flow structures that are different from those resulting when only one of these effects is present. The present paper focuses on this interaction using the liquid bridge geometry as a paradigmatic system for the analysis. Such analysis is based on an appropriate post-processing of the results obtained via direct numerical simulation of the system for moderately small viscosity, a condition consistent with typical experiments of vibrated millimetric liquid bridges. It is seen that the flow patterns show a nonmonotone behavior as the Marangoni number is increased. In addition, the strength of the mean flow at the free surface exhibits two well-defined regimes as the forcing amplitude increases. These regimes show fairly universal power-law behaviors.

  7. Analysis of a 7 year tropospheric ozone vertical distribution at the Observatoire de Haute Provence

    NASA Technical Reports Server (NTRS)

    Beekmann, Matthias; Ancellet, Gerard; Megie, Gerard

    1994-01-01

    A seven year (1984-90) climatology of tropospheric vertical ozone soundings, performed by electrochemical sondes at the OHP (44 deg N, 6 deg E, 700 m ASL) in Southern France, is presented. Its seasonal variation shows a broad spring/summer maximum in the troposphere. The contribution of photochemical ozone production and transport from the stratosphere to this seasonal variation are studied by a correlative analysis of ozone concentrations and meteorological variables, with emphasis on potential vorticity. This analysis shows the impact of dynamical and photochemical processes on the spatial and temporal ozone variability. In particular, a positive correlation (r = 04.0, significance greater than 99.9 percent) of ozone with potential vorticity is observed in the middle troposphere, reflecting the impact of stratosphere-troposphere exchange on the vertical ozone distribution.

  8. Detection of traffic incidents using nonlinear time series analysis

    NASA Astrophysics Data System (ADS)

    Fragkou, A. D.; Karakasidis, T. E.; Nathanail, E.

    2018-06-01

    In this study, we present results of the application of nonlinear time series analysis on traffic data for incident detection. More specifically, we analyze daily volume records of Attica Tollway (Greece) collected from sensors located at various locations. The analysis was performed using the Recurrence Plot (RP) and Recurrence Quantification Analysis (RQA) method of the volume data of the lane closest to the median. The results show that it is possible to identify, through the abrupt change of the dynamics of the system revealed by RPs and RQA, the occurrence of incidents on the freeway and differentiate from recurrent traffic congestion. The proposed methodology could be of interest for big data traffic analysis.

  9. Quantifying Low Energy Proton Damage in Multijunction Solar Cells

    NASA Technical Reports Server (NTRS)

    Messenger, Scott R.; Burke, Edward A.; Walters, Robert J.; Warner, Jeffrey H.; Summers, Geoffrey P.; Lorentzen, Justin R.; Morton, Thomas L.; Taylor, Steven J.

    2007-01-01

    An analysis of the effects of low energy proton irradiation on the electrical performance of triple junction (3J) InGaP2/GaAs/Ge solar cells is presented. The Monte Carlo ion transport code (SRIM) is used to simulate the damage profile induced in a 3J solar cell under the conditions of typical ground testing and that of the space environment. The results are used to present a quantitative analysis of the defect, and hence damage, distribution induced in the cell active region by the different radiation conditions. The modelling results show that, in the space environment, the solar cell will experience a uniform damage distribution through the active region of the cell. Through an application of the displacement damage dose analysis methodology, the implications of this result on mission performance predictions are investigated.

  10. Hydromagnetic couple-stress nanofluid flow over a moving convective wall: OHAM analysis

    NASA Astrophysics Data System (ADS)

    Awais, M.; Saleem, S.; Hayat, T.; Irum, S.

    2016-12-01

    This communication presents the magnetohydrodynamics (MHD) flow of a couple-stress nanofluid over a convective moving wall. The flow dynamics are analyzed in the boundary layer region. Convective cooling phenomenon combined with thermophoresis and Brownian motion effects has been discussed. Similarity transforms are utilized to convert the system of partial differential equations into coupled non-linear ordinary differential equation. Optimal homotopy analysis method (OHAM) is utilized and the concept of minimization is employed by defining the average squared residual errors. Effects of couple-stress parameter, convective cooling process parameter and energy enhancement parameters are displayed via graphs and discussed in detail. Various tables are also constructed to present the error analysis and a comparison of obtained results with the already published data. Stream lines are plotted showing a difference of Newtonian fluid model and couplestress fluid model.

  11. Nursing informatics competencies: bibliometric analysis.

    PubMed

    Kokol, Peter; Blažun, Helena; Vošner, Janez; Saranto, Kaija

    2014-01-01

    Information and communication technology is developing rapidly and it is incorporated in many health care processes, but in spite of that fact we can still notice that nursing informatics competencies had received limited attention in basic nursing education curricula in Europe and especially in Eastern European countries. The purpose of the present paper is to present the results of a bibliometric analysis of the nursing informatics competencies scientific literature production. We applied the bibliometrics analysis to the corpus of 332 papers found in SCOPUS, related to nursing informatics competencies. The results showed that there is a positive trend in the number of published papers per year, indicating the increased research interest in nursing informatics competencies. Despite the fact that the first paper was published in Denmark, the most prolific country regarding the research in nursing informatics competencies is United States as are their institutions and authors.

  12. Structural Design and Analysis of the Upper Pressure Shell Section of a Composite Crew Module

    NASA Technical Reports Server (NTRS)

    Sleight, David W.; Paddock, David; Jeans, Jim W.; Hudeck, John D.

    2008-01-01

    This paper presents the results of the structural design and analysis of the upper pressure shell section of a carbon composite demonstration structure for the Composite Crew Module (CCM) Project. The project is managed by the NASA Engineering and Safety Center with participants from eight NASA Centers, the Air Force Research Laboratory, and multiple aerospace contractors including ATK/Swales, Northrop Grumman, Lockheed Martin, Collier Research Corporation, Genesis Engineering, and Janicki Industries. The paper discusses details of the upper pressure shell section design of the CCM and presents the structural analysis results using the HyperSizer structural sizing software and the MSC Nastran finite element analysis software. The HyperSizer results showed that the controlling load case driving most of the sizing in the upper pressure shell section was the internal pressure load case. The regions around the cutouts were controlled by internal pressure and the main parachute load cases. The global finite element analysis results showed that the majority of the elements of the CCM had a positive margin of safety with the exception of a few hot spots around the cutouts. These hot spots are currently being investigated with a more detailed analysis. Local finite element models of the Low Impact Docking System (LIDS) interface ring and the forward bay gussets with greater mesh fidelity were created for local sizing and analysis. The sizing of the LIDS interface ring was driven by the drogue parachute loads, Trans-Lunar Insertion (TLI) loads, and internal pressure. The drogue parachute loads controlled the sizing of the gusset cap on the drogue gusset and TLI loads controlled the sizing of the other five gusset caps. The main parachute loads controlled the sizing of the lower ends of the gusset caps on the main parachute fittings. The results showed that the gusset web/pressure shell and gusset web/gusset cap interfaces bonded using Pi-preform joints had local hot spots in the Pi-preform termination regions. These regions require a detailed three-dimensional analysis, which is currently being performed, to accurately address the load distribution near the Pi-preform termination in the upper and lower gusset caps.

  13. [Pneumoconiosis in bauxite miners].

    PubMed

    Molinini, R; Pesola, M; Digennaro, M A; Carino, M; Nuzzaco, A; Coviello, F

    1985-01-01

    The authors examined a group of 40 miners who were being working at an Apulian bauxite mine, presently inactive. Radiographic findings of pulmonary micronodulation without significant reduction of lung functions were showed in 15 miners. Mineralogical analysis of mine dust samples excluded any presence of more than 1% free silica. As a result of this study hypotheses have been formulated about pathogenesis of this moderated and non-invasive pneumoconiosis, showed in long exposed subjects to low silica content dusts.

  14. Modeling spanwise nonuniformity in the cross-sectional analysis of composite beams

    NASA Astrophysics Data System (ADS)

    Ho, Jimmy Cheng-Chung

    Spanwise nonuniformity effects are modeled in the cross-sectional analysis of beam theory. This modeling adheres to an established numerical framework on cross-sectional analysis of uniform beams with arbitrary cross-sections. This framework is based on two concepts: decomposition of the rotation tensor and the variational-asymptotic method. Allowance of arbitrary materials and geometries in the cross-section is from discretization of the warping field by finite elements. By this approach, dimensional reduction from three-dimensional elasticity is performed rigorously and the sectional strain energy is derived to be asymptotically-correct. Elastic stiffness matrices are derived for inputs into the global beam analysis. Recovery relations for the displacement, stress, and strain fields are also derived with care to be consistent with the energy. Spanwise nonuniformity effects appear in the form of pointwise and sectionwise derivatives, which are approximated by finite differences. The formulation also accounts for the effects of spanwise variations in initial twist and/or curvature. A linearly tapered isotropic strip is analyzed to demonstrate spanwise nonuniformity effects on the cross-sectional analysis. The analysis is performed analytically by the variational-asymptotic method. Results from beam theory are validated against solutions from plane stress elasticity. These results demonstrate that spanwise nonuniformity effects become significant as the rate at which the cross-sections vary increases. The modeling of transverse shear modes of deformation is accomplished by transforming the strain energy into generalized Timoshenko form. Approximations in this transformation procedure from previous works, when applied to uniform beams, are identified. The approximations are not used in the present work so as to retain more accuracy. Comparison of present results with those previously published shows that these approximations sometimes change the results measurably and thus are inappropriate. Static and dynamic results, from the global beam analysis, are calculated to show the differences between using stiffness constants from previous works and the present work. As a form of validation of the transformation procedure, calculations from the global beam analysis of initially twisted isotropic beams from using curvilinear coordinate axes featuring twist are shown to be equivalent to calculations using Cartesian coordinates.

  15. Acute Toxic Neuropathy Mimicking Guillain Barre Syndrome

    PubMed Central

    Jalal, Muhammed Jasim Abdul; Fernandez, Shirley Joan; Menon, Murali Krishna

    2015-01-01

    Case: A 30 year old male presented with numbness of palms and soles followed by weakness of upper limbs and lower limbs of 5 days duration, which was ascending and progressive. Three months back he was treated for oral and genital ulcers with oral steroids. His ulcers improved and shifted to indigenous medication. His clinical examination showed polyneuropathy. CSF study did not show albuminocytological dissociation. Nerve conduction study showed demyelinating polyneuropathy. His blood samples and the ayurvedic drug samples were sent for toxicological analysis. Inference: Acute toxic neuropathy - Arsenic PMID:25811007

  16. Analytical Study of Gravity Effects on Laminar Diffusion Flames

    NASA Technical Reports Server (NTRS)

    Edelman, R. B.; Fortune, O.; Weilerstein, G.

    1972-01-01

    A mathematical model is presented for the description of axisymmetric laminar-jet diffusion flames. The analysis includes the effects of inertia, viscosity, diffusion, gravity and combustion. These mechanisms are coupled in a boundary layer type formulation and solutions are obtained by an explicit finite difference technique. A dimensional analysis shows that the maximum flame width radius, velocity and thermodynamic state characterize the flame structure. Comparisons with experimental data showed excellent agreement for normal gravity flames and fair agreement for steady state low Reynolds number zero gravity flames. Kinetics effects and radiation are shown to be the primary mechanisms responsible for this discrepancy. Additional factors are discussed including elipticity and transient effects.

  17. Cryptanalysis of Chatterjee-Sarkar Hierarchical Identity-Based Encryption Scheme at PKC 06

    NASA Astrophysics Data System (ADS)

    Park, Jong Hwan; Lee, Dong Hoon

    In 2006, Chatterjee and Sarkar proposed a hierarchical identity-based encryption (HIBE) scheme which can support an unbounded number of identity levels. This property is particularly useful in providing forward secrecy by embedding time components within hierarchical identities. In this paper we show that their scheme does not provide the claimed property. Our analysis shows that if the number of identity levels becomes larger than the value of a fixed public parameter, an unintended receiver can reconstruct a new valid ciphertext and decrypt the ciphertext using his or her own private key. The analysis is similarly applied to a multi-receiver identity-based encryption scheme presented as an application of Chatterjee and Sarkar's HIBE scheme.

  18. Disputed climate science in the media: do countries matter?

    PubMed

    Grundmann, Reiner; Scott, Mike

    2014-02-01

    This article presents findings from a large-scale newspaper analysis of climate change discourses in four developed countries, using corpus linguistics methodology. We map the discourse over time, showing peaks and troughs of attention and explaining their causes. Different connotations of common terms such as global warming and climate change in different countries are analysed. Cluster and key-word analysis show the relative salience of specific words and word combinations during crucial periods. We identify main claims makers and the relative visibility of advocates and sceptics. The main finding is that former are far more prominent in all countries. We also look at the coverage of 'climategate'. Finally, we make reference to existing theoretical frameworks.

  19. Feed-forward control of gear mesh vibration using piezoelectric actuators

    NASA Technical Reports Server (NTRS)

    Montague, Gerald T.; Kascak, Albert F.; Palazzolo, Alan; Manchala, Daniel; Thomas, Erwin

    1994-01-01

    This paper presents a novel means for suppressing gear mesh-related vibrations. The key components in this approach are piezoelectric actuators and a high-frequency, analog feed-forward controller. Test results are presented and show up to a 70-percent reduction in gear mesh acceleration and vibration control up to 4500 Hz. The principle of the approach is explained by an analysis of a harmonically excited, general linear vibratory system.

  20. NASA TLA workload analysis support. Volume 2: Metering and spacing studies validation data

    NASA Technical Reports Server (NTRS)

    Sundstrom, J. L.

    1980-01-01

    Four sets of graphic reports--one for each of the metering and spacing scenarios--are presented. The complete data file from which the reports were generated is also given. The data was used to validate the detail task of both the pilot and copilot for four metering and spacing scenarios. The output presents two measures of demand workload and a report showing task length and task interaction.

  1. Workshop on dimensional analysis for design, development, and research executives

    NASA Technical Reports Server (NTRS)

    Goodman, R. A.; Abernathy, W. J.

    1971-01-01

    The proceedings of a conference of research and development executives are presented. The purpose of the meeting was to develop an understanding of the conditions which are appropriate for the use of certain general management tools and those conditions which render these tools inappropriate. The verbatim statements of the participants are included to show the direction taken initially by the conference. Formal presentations of management techniques for research and development are developed.

  2. Forensic Carving of Network Packets and Associated Data Structures

    DTIC Science & Technology

    2011-01-01

    establishment of prior connection activity and services used; identification of other systems present on the system’s LAN or WLAN; geolocation of the...identification of other systems present on the system?s LAN or WLAN; geolocation of the host computer system; and cross-drive analysis. We show that network...Finally, our work in geolocation was assisted by geo- location databases created by companies such as Google (Google Mobile, 2011) and Skyhook

  3. Runaway Costs in Medi-Cal—A Myth

    PubMed Central

    Heckman, John R.; Jones, Michael W.

    1980-01-01

    An analysis of increases in Medi-Cal expenditures to their present level, more than $4 billion a year, shows them to be attributable largely to changes in eligibility and scope of benefits. The actual costs of providing care have risen at a relatively modest rate. If in fact costs are to be lowered from present levels, public policy makers must make important decisions concerning program changes which transcend merely altering payment and delivery methods. PMID:6996335

  4. The reliability analysis of a separated, dual fail operational redundant strapdown IMU. [inertial measurement unit

    NASA Technical Reports Server (NTRS)

    Motyka, P.

    1983-01-01

    A methodology for quantitatively analyzing the reliability of redundant avionics systems, in general, and the dual, separated Redundant Strapdown Inertial Measurement Unit (RSDIMU), in particular, is presented. The RSDIMU is described and a candidate failure detection and isolation system presented. A Markov reliability model is employed. The operational states of the system are defined and the single-step state transition diagrams discussed. Graphical results, showing the impact of major system parameters on the reliability of the RSDIMU system, are presented and discussed.

  5. An equivalent domain integral method in the two-dimensional analysis of mixed mode crack problems

    NASA Technical Reports Server (NTRS)

    Raju, I. S.; Shivakumar, K. N.

    1990-01-01

    An equivalent domain integral (EDI) method for calculating J-integrals for two-dimensional cracked elastic bodies is presented. The details of the method and its implementation are presented for isoparametric elements. The EDI method gave accurate values of the J-integrals for two mode I and two mixed mode problems. Numerical studies showed that domains consisting of one layer of elements are sufficient to obtain accurate J-integral values. Two procedures for separating the individual modes from the domain integrals are presented.

  6. Two-dimensional random surface model for asperity-contact in elastohydrodynamic lubrication

    NASA Technical Reports Server (NTRS)

    Coy, J. J.; Sidik, S. M.

    1979-01-01

    Relations for the asperity-contact time function during elastohydrodynamic lubrication of a ball bearing are presented. The analysis is based on a two-dimensional random surface model, and actual profile traces of the bearing surfaces are used as statistical sample records. The results of the analysis show that transition from 90 percent contact to 1 percent contact occurs within a dimensionless film thickness range of approximately four to five. This thickness ratio is several times large than reported in the literature where one-dimensional random surface models were used. It is shown that low pass filtering of the statistical records will bring agreement between the present results and those in the literature.

  7. Virtual Estimator for Piecewise Linear Systems Based on Observability Analysis

    PubMed Central

    Morales-Morales, Cornelio; Adam-Medina, Manuel; Cervantes, Ilse; Vela-Valdés and, Luis G.; García Beltrán, Carlos Daniel

    2013-01-01

    This article proposes a virtual sensor for piecewise linear systems based on observability analysis that is in function of a commutation law related with the system's outpu. This virtual sensor is also known as a state estimator. Besides, it presents a detector of active mode when the commutation sequences of each linear subsystem are arbitrary and unknown. For the previous, this article proposes a set of virtual estimators that discern the commutation paths of the system and allow estimating their output. In this work a methodology in order to test the observability for piecewise linear systems with discrete time is proposed. An academic example is presented to show the obtained results. PMID:23447007

  8. How to become a superhero

    NASA Astrophysics Data System (ADS)

    Gleiser, Pablo M.

    2007-09-01

    We analyze a collaboration network based on the Marvel Universe comic books. First, we consider the system as a binary network, where two characters are connected if they appear in the same publication. The analysis of degree correlations reveals that, in contrast to most real social networks, the Marvel Universe presents a disassortative mixing on the degree. Then, we use a weight measure to study the system as a weighted network. This allows us to find and characterize well defined communities. Through the analysis of the community structure and the clustering as a function of the degree we show that the network presents a hierarchical structure. Finally, we comment on possible mechanisms responsible for the particular motifs observed.

  9. "Shades of Foreign Evil": "Honor Killings" and "Family Murders" in the Canadian Press.

    PubMed

    Shier, Allie; Shor, Eran

    2016-09-01

    This article compares murder cases labeled "honor killings" with cases labeled "family/spousal murders" in the Canadian news media, exploring the construction of boundaries between these two practices. We conducted a systematic qualitative content analysis, examining a sample of 486 articles from three major Canadian newspapers between 2000 and 2012. Our analysis shows that "honor killings" are framed in terms of culture and ethnic background, presenting a dichotomy between South Asian/Muslim and Western values. Conversely, articles presenting cases as "family/spousal murders" tend to focus on the perpetrators' personalities or psychological characteristics, often ignoring factors such as culture, patriarchy, honor, and shame. © The Author(s) 2015.

  10. An Expert Assistant for Computer Aided Parallelization

    NASA Technical Reports Server (NTRS)

    Jost, Gabriele; Chun, Robert; Jin, Haoqiang; Labarta, Jesus; Gimenez, Judit

    2004-01-01

    The prototype implementation of an expert system was developed to assist the user in the computer aided parallelization process. The system interfaces to tools for automatic parallelization and performance analysis. By fusing static program structure information and dynamic performance analysis data the expert system can help the user to filter, correlate, and interpret the data gathered by the existing tools. Sections of the code that show poor performance and require further attention are rapidly identified and suggestions for improvements are presented to the user. In this paper we describe the components of the expert system and discuss its interface to the existing tools. We present a case study to demonstrate the successful use in full scale scientific applications.

  11. Classification of Magnetic Nanoparticle Systems—Synthesis, Standardization and Analysis Methods in the NanoMag Project

    PubMed Central

    Bogren, Sara; Fornara, Andrea; Ludwig, Frank; del Puerto Morales, Maria; Steinhoff, Uwe; Fougt Hansen, Mikkel; Kazakova, Olga; Johansson, Christer

    2015-01-01

    This study presents classification of different magnetic single- and multi-core particle systems using their measured dynamic magnetic properties together with their nanocrystal and particle sizes. The dynamic magnetic properties are measured with AC (dynamical) susceptometry and magnetorelaxometry and the size parameters are determined from electron microscopy and dynamic light scattering. Using these methods, we also show that the nanocrystal size and particle morphology determines the dynamic magnetic properties for both single- and multi-core particles. The presented results are obtained from the four year EU NMP FP7 project, NanoMag, which is focused on standardization of analysis methods for magnetic nanoparticles. PMID:26343639

  12. Percolation analyses of observed and simulated galaxy clustering

    NASA Astrophysics Data System (ADS)

    Bhavsar, S. P.; Barrow, J. D.

    1983-11-01

    A percolation cluster analysis is performed on equivalent regions of the CFA redshift survey of galaxies and the 4000 body simulations of gravitational clustering made by Aarseth, Gott and Turner (1979). The observed and simulated percolation properties are compared and, unlike correlation and multiplicity function analyses, favour high density (Omega = 1) models with n = - 1 initial data. The present results show that the three-dimensional data are consistent with the degree of filamentary structure present in isothermal models of galaxy formation at the level of percolation analysis. It is also found that the percolation structure of the CFA data is a function of depth. Percolation structure does not appear to be a sensitive probe of intrinsic filamentary structure.

  13. Segmentation of touching mycobacterium tuberculosis from Ziehl-Neelsen stained sputum smear images

    NASA Astrophysics Data System (ADS)

    Xu, Chao; Zhou, Dongxiang; Liu, Yunhui

    2015-12-01

    Touching Mycobacterium tuberculosis objects in the Ziehl-Neelsen stained sputum smear images present different shapes and invisible boundaries in the adhesion areas, which increases the difficulty in objects recognition and counting. In this paper, we present a segmentation method of combining the hierarchy tree analysis with gradient vector flow snake to address this problem. The skeletons of the objects are used for structure analysis based on the hierarchy tree. The gradient vector flow snake is used to estimate the object edge. Experimental results show that the single objects composing the touching objects are successfully segmented by the proposed method. This work will improve the accuracy and practicability of the computer-aided diagnosis of tuberculosis.

  14. Performance of ITER as a burning plasma experiment

    NASA Astrophysics Data System (ADS)

    Shimada, M.; Mukhovatov, V.; Federici, G.; Gribov, Y.; Kukushkin, A.; Murakami, Y.; Polevoi, A.; Pustovitov, V.; Sengoku, S.; Sugihara, M.

    2004-02-01

    Recent performance analysis has improved confidence in achieving Q (= fusion power/auxiliary heating power)geq 10 in inductive operation in ITER. Performance analysis based on empirical scalings shows the feasibility of achieving Q geq 10 in inductive operation, particularly with improved modelling of helium exhaust. Analysis has also indicated the possibility that ITER can potentially demonstrate Q ~ 50, enabling studies of self-heated plasmas. Theory-based core modelling indicates the need for a high pedestal temperature (3.2-5.3 keV) to achieve Q geq 10, which is in the range of projections with presently available pedestal scalings. Pellet injection from the high-field side would be useful in enhancing Q and reducing edge localized mode (ELM) heat load in high plasma current operation. If the ELM heat load is not acceptable, it could be made tolerable by further tilting the target plate. Steady state operation scenarios at Q = 5 have been developed with modest requirements on confinement improvement and beta (HH98(y,2) geq 1.3 and bgrN geq 2.6). Stabilization of the resistive wall modes (RWMs), required in such regimes, is feasible with the present saddle coils and power supplies with double-wall structures taken into account. Recent analysis shows a potential of high power steady state operation with a fusion power of 0.7 GW at Q ~ 8. Achievement of the required bgrN ~ 3.6 by RWM stabilization is a possibility. Further analysis is also needed on reduction of the divertor target heat load.

  15. Monitoring of Students' Interaction in Online Learning Settings by Structural Network Analysis and Indicators.

    PubMed

    Ammenwerth, Elske; Hackl, Werner O

    2017-01-01

    Learning as a constructive process works best in interaction with other learners. Support of social interaction processes is a particular challenge within online learning settings due to the spatial and temporal distribution of participants. It should thus be carefully monitored. We present structural network analysis and related indicators to analyse and visualize interaction patterns of participants in online learning settings. We validate this approach in two online courses and show how the visualization helps to monitor interaction and to identify activity profiles of learners. Structural network analysis is a feasible approach for an analysis of the intensity and direction of interaction in online learning settings.

  16. Method for improving accuracy in full evaporation headspace analysis.

    PubMed

    Xie, Wei-Qi; Chai, Xin-Sheng

    2017-05-01

    We report a new headspace analytical method in which multiple headspace extraction is incorporated with the full evaporation technique. The pressure uncertainty caused by the solid content change in the samples has a great impact to the measurement accuracy in the conventional full evaporation headspace analysis. The results (using ethanol solution as the model sample) showed that the present technique is effective to minimize such a problem. The proposed full evaporation multiple headspace extraction analysis technique is also automated and practical, and which could greatly broaden the applications of the full-evaporation-based headspace analysis. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Bell scenarios in which nonlocality and entanglement are inversely related

    NASA Astrophysics Data System (ADS)

    Vallone, Giuseppe; Lima, Gustavo; Gómez, Esteban S.; Cañas, Gustavo; Larsson, Jan-Åke; Mataloni, Paolo; Cabello, Adán

    2014-06-01

    Several studies in recent years have demonstrated that upper-division students struggle with the mathematics of thermodynamics. This paper presents a task analysis based on several expert attempts to solve a challenging mathematics problem in thermodynamics. The purpose of this paper is twofold. First, we highlight the importance of cognitive task analysis for understanding expert performance and show how the epistemic games framework can be used as a tool for this type of analysis, with thermodynamics as an example. Second, through this analysis, we identify several issues related to thermodynamics that are relevant to future research into student understanding and learning of the mathematics of thermodynamics.

  18. Thermal analysis and microstructural characterization of Mg-Al-Zn system alloys

    NASA Astrophysics Data System (ADS)

    Król, M.; Tański, T.; Sitek, W.

    2015-11-01

    The influence of Zn amount and solidification rate on the characteristic temperature of the evaluation of magnesium dendrites during solidification at different cooling rates (0.6-2.5°C) were examined by thermal derivative analysis (TDA). The dendrite coherency point (DCP) is presented with a novel approach based on second derivative cooling curve. Solidification behavior was examined via one thermocouple thermal analysis method. Microstructural assessments were described by optical light microscopy, scanning electron microscopy and energy dispersive X-ray spectroscopy. These studies showed that utilization of d2T/dt2 vs. the time curve methodology provides for analysis of the dendrite coherency point

  19. Visualising nursing data using correspondence analysis.

    PubMed

    Kokol, Peter; Blažun Vošner, Helena; Železnik, Danica

    2016-09-01

    Digitally stored, large healthcare datasets enable nurses to use 'big data' techniques and tools in nursing research. Big data is complex and multi-dimensional, so visualisation may be a preferable approach to analyse and understand it. To demonstrate the use of visualisation of big data in a technique called correspondence analysis. In the authors' study, relations among data in a nursing dataset were shown visually in graphs using correspondence analysis. The case presented demonstrates that correspondence analysis is easy to use, shows relations between data visually in a form that is simple to interpret, and can reveal hidden associations between data. Correspondence analysis supports the discovery of new knowledge. Implications for practice Knowledge obtained using correspondence analysis can be transferred immediately into practice or used to foster further research.

  20. Identifying online user reputation of user-object bipartite networks

    NASA Astrophysics Data System (ADS)

    Liu, Xiao-Lu; Liu, Jian-Guo; Yang, Kai; Guo, Qiang; Han, Jing-Ti

    2017-02-01

    Identifying online user reputation based on the rating information of the user-object bipartite networks is important for understanding online user collective behaviors. Based on the Bayesian analysis, we present a parameter-free algorithm for ranking online user reputation, where the user reputation is calculated based on the probability that their ratings are consistent with the main part of all user opinions. The experimental results show that the AUC values of the presented algorithm could reach 0.8929 and 0.8483 for the MovieLens and Netflix data sets, respectively, which is better than the results generated by the CR and IARR methods. Furthermore, the experimental results for different user groups indicate that the presented algorithm outperforms the iterative ranking methods in both ranking accuracy and computation complexity. Moreover, the results for the synthetic networks show that the computation complexity of the presented algorithm is a linear function of the network size, which suggests that the presented algorithm is very effective and efficient for the large scale dynamic online systems.

  1. First Case of Canine Infection with Hepatozoon canis (Apicomplexa: Haemogregarinidae) in the Republic of Korea.

    PubMed

    Kwon, Seung-Joo; Kim, Yoon-Hee; Oh, Hyun-Hee; Choi, Ul-Soo

    2017-10-01

    This report describes a dog infected with Hepatozoon canis, the first canine infection in the Republic of Korea. A 2-year-old intact male Maltese dog presented with anorexia and depression. Physical examinations revealed mild dehydration and hyperthermia (39.8°C), and blood analysis showed pancytopenia. Diff-Quik staining of blood smear specimens showed the presence of ellipsoidal shaped structures (gamonts of H. canis) within a small number of neutrophils. Real-time PCR analysis using whole blood confirmed infection by H. canis. The clinical condition of the dog improved after symptomatic treatment and administration of doxycycline. Although a molecular epidemiologic survey in Korea showed H. canis infection of dogs, to our knowledge this is the first report of a dog infection in Korea molecularly shown to be H. canis.

  2. First Case of Canine Infection with Hepatozoon canis (Apicomplexa: Haemogregarinidae) in the Republic of Korea

    PubMed Central

    Kwon, Seung-Joo; Kim, Yoon-Hee; Oh, Hyun-Hee; Choi, Ul-Soo

    2017-01-01

    This report describes a dog infected with Hepatozoon canis, the first canine infection in the Republic of Korea. A 2-year-old intact male Maltese dog presented with anorexia and depression. Physical examinations revealed mild dehydration and hyperthermia (39.8°C), and blood analysis showed pancytopenia. Diff-Quik staining of blood smear specimens showed the presence of ellipsoidal shaped structures (gamonts of H. canis) within a small number of neutrophils. Real-time PCR analysis using whole blood confirmed infection by H. canis. The clinical condition of the dog improved after symptomatic treatment and administration of doxycycline. Although a molecular epidemiologic survey in Korea showed H. canis infection of dogs, to our knowledge this is the first report of a dog infection in Korea molecularly shown to be H. canis. PMID:29103272

  3. Texture analysis based on the Hermite transform for image classification and segmentation

    NASA Astrophysics Data System (ADS)

    Estudillo-Romero, Alfonso; Escalante-Ramirez, Boris; Savage-Carmona, Jesus

    2012-06-01

    Texture analysis has become an important task in image processing because it is used as a preprocessing stage in different research areas including medical image analysis, industrial inspection, segmentation of remote sensed imaginary, multimedia indexing and retrieval. In order to extract visual texture features a texture image analysis technique is presented based on the Hermite transform. Psychovisual evidence suggests that the Gaussian derivatives fit the receptive field profiles of mammalian visual systems. The Hermite transform describes locally basic texture features in terms of Gaussian derivatives. Multiresolution combined with several analysis orders provides detection of patterns that characterizes every texture class. The analysis of the local maximum energy direction and steering of the transformation coefficients increase the method robustness against the texture orientation. This method presents an advantage over classical filter bank design because in the latter a fixed number of orientations for the analysis has to be selected. During the training stage, a subset of the Hermite analysis filters is chosen in order to improve the inter-class separability, reduce dimensionality of the feature vectors and computational cost during the classification stage. We exhaustively evaluated the correct classification rate of real randomly selected training and testing texture subsets using several kinds of common used texture features. A comparison between different distance measurements is also presented. Results of the unsupervised real texture segmentation using this approach and comparison with previous approaches showed the benefits of our proposal.

  4. Eigenvalue-eigenvector decomposition (EED) analysis of dissimilarity and covariance matrix obtained from total synchronous fluorescence spectral (TSFS) data sets of herbal preparations: Optimizing the classification approach.

    PubMed

    Tarai, Madhumita; Kumar, Keshav; Divya, O; Bairi, Partha; Mishra, Kishor Kumar; Mishra, Ashok Kumar

    2017-09-05

    The present work compares the dissimilarity and covariance based unsupervised chemometric classification approaches by taking the total synchronous fluorescence spectroscopy data sets acquired for the cumin and non-cumin based herbal preparations. The conventional decomposition method involves eigenvalue-eigenvector analysis of the covariance of the data set and finds the factors that can explain the overall major sources of variation present in the data set. The conventional approach does this irrespective of the fact that the samples belong to intrinsically different groups and hence leads to poor class separation. The present work shows that classification of such samples can be optimized by performing the eigenvalue-eigenvector decomposition on the pair-wise dissimilarity matrix. Copyright © 2017 Elsevier B.V. All rights reserved.

  5. Unobtrusive Biometric System Based on Electroencephalogram Analysis

    NASA Astrophysics Data System (ADS)

    Riera, A.; Soria-Frisch, A.; Caparrini, M.; Grau, C.; Ruffini, G.

    2007-12-01

    Features extracted from electroencephalogram (EEG) recordings have proved to be unique enough between subjects for biometric applications. We show here that biometry based on these recordings offers a novel way to robustly authenticate or identify subjects. In this paper, we present a rapid and unobtrusive authentication method that only uses 2 frontal electrodes referenced to another one placed at the ear lobe. Moreover, the system makes use of a multistage fusion architecture, which demonstrates to improve the system performance. The performance analysis of the system presented in this paper stems from an experiment with 51 subjects and 36 intruders, where an equal error rate (EER) of 3.4% is obtained, that is, true acceptance rate (TAR) of 96.6% and a false acceptance rate (FAR) of 3.4%. The obtained performance measures improve the results of similar systems presented in earlier work.

  6. Leadership for Community Engagement--A Distributed Leadership Perspective

    ERIC Educational Resources Information Center

    Liang, Jia G.; Sandmann, Lorilee R.

    2015-01-01

    This article presents distributed leadership as a framework for analysis, showing how the phenomenon complements formal higher education structures by mobilizing leadership from various sources, formal and informal. This perspective more accurately portrays the reality of leading engaged institutions. Using the application data from 224…

  7. Approaching the Limit in Atomic Spectrochemical Analysis.

    ERIC Educational Resources Information Center

    Hieftje, Gary M.

    1982-01-01

    To assess the ability of current analytical methods to approach the single-atom detection level, theoretical and experimentally determined detection levels are presented for several chemical elements. A comparison of these methods shows that the most sensitive atomic spectrochemical technique currently available is based on emission from…

  8. Content Structure as a Design Strategy Variable in Concept Acquisition.

    ERIC Educational Resources Information Center

    Tennyson, Robert D.; Tennyson, Carol L.

    Three methods of sequencing coordinate concepts (simultaneous, collective, and successive) were investigated with a Bayesian, computer-based, adaptive control system. The data analysis showed that when coordinate concepts are taught simultaneously (contextually similar concepts presented at the same time), student performance is superior to either…

  9. Genome-wide analysis of alternative splicing during human heart development

    NASA Astrophysics Data System (ADS)

    Wang, He; Chen, Yanmei; Li, Xinzhong; Chen, Guojun; Zhong, Lintao; Chen, Gangbing; Liao, Yulin; Liao, Wangjun; Bin, Jianping

    2016-10-01

    Alternative splicing (AS) drives determinative changes during mouse heart development. Recent high-throughput technological advancements have facilitated genome-wide AS, while its analysis in human foetal heart transition to the adult stage has not been reported. Here, we present a high-resolution global analysis of AS transitions between human foetal and adult hearts. RNA-sequencing data showed extensive AS transitions occurred between human foetal and adult hearts, and AS events occurred more frequently in protein-coding genes than in long non-coding RNA (lncRNA). A significant difference of AS patterns was found between foetal and adult hearts. The predicted difference in AS events was further confirmed using quantitative reverse transcription-polymerase chain reaction analysis of human heart samples. Functional foetal-specific AS event analysis showed enrichment associated with cell proliferation-related pathways including cell cycle, whereas adult-specific AS events were associated with protein synthesis. Furthermore, 42.6% of foetal-specific AS events showed significant changes in gene expression levels between foetal and adult hearts. Genes exhibiting both foetal-specific AS and differential expression were highly enriched in cell cycle-associated functions. In conclusion, we provided a genome-wide profiling of AS transitions between foetal and adult hearts and proposed that AS transitions and deferential gene expression may play determinative roles in human heart development.

  10. Genome-wide identification of multifunctional laccase gene family in cotton (Gossypium spp.); expression and biochemical analysis during fiber development

    PubMed Central

    Balasubramanian, Vimal Kumar; Rai, Krishan Mohan; Thu, Sandi Win; Hii, Mei Mei; Mendu, Venugopal

    2016-01-01

    The single-celled cotton fibers, produced from seed coat epidermal cells are the largest natural source of textile fibers. The economic value of cotton fiber lies in its length and quality. The multifunctional laccase enzymes play important roles in cell elongation, lignification and pigmentation in plants and could play crucial role in cotton fiber quality. Genome-wide analysis of cultivated allotetraploid (G. hirsutum) and its progenitor diploid (G. arboreum and G. raimondii) cotton species identified 84, 44 and 46 laccase genes, respectively. Analysis of chromosomal location, phylogeny, conserved domain and physical properties showed highly conserved nature of laccases across three cotton species. Gene expression, enzymatic activity and biochemical analysis of developing cotton fibers was performed using G. arboreum species. Of the total 44, 40 laccases showed expression during different stages of fiber development. The higher enzymatic activity of laccases correlated with higher lignin content at 25 DPA (Days Post Anthesis). Further, analysis of cotton fiber phenolic compounds showed an overall decrease at 25 DPA indicating possible incorporation of these substrates into lignin polymer during secondary cell wall biosynthesis. Overall data indicate significant roles of laccases in cotton fiber development, and presents an excellent opportunity for manipulation of fiber development and quality. PMID:27679939

  11. Measurement of Workload: Physics, Psychophysics, and Metaphysics

    NASA Technical Reports Server (NTRS)

    Gopher, D.

    1984-01-01

    The present paper reviews the results of two experiments in which workload analysis was conducted based upon performance measures, brain evoked potentials and magnitude estimations of subjective load. The three types of measures were jointly applied to the description of the behavior of subjects in a wide battery of experimental tasks. Data analysis shows both instances of association and dissociation between types of measures. A general conceptual framework and methodological guidelines are proposed to account for these findings.

  12. Recent Progress of Microfluidics in Translational Applications

    PubMed Central

    Liu, Zongbin; Han, Xin

    2016-01-01

    Microfluidics, featuring microfabricated structures, is a technology for manipulating fluids at the micrometer scale. The small dimension and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design is presented. The potential future developments in the translational microfluidics field are also discussed. PMID:27091777

  13. [Reconstruction of sexual offences--forensic aspects of sperm traces].

    PubMed

    Laberke, Patrick J; Bockholdt, Britta; Hausmann, Roland; Balitzki, Beate

    2010-01-01

    The investigation of sexual offences is a real challenge, as the injuries are often unspecific or faint and may sometimes be missing completely. Evidence recovery and analysis as well as the statements of the victims and suspects are therefore of vital importance. In both presented cases, the results of trace evidence analysis were basically consistent with a sexual assault, but the victims' statements regarding the course of events and the pattern of traces showed severe discrepancies.

  14. Astrobiology and the Chemistry of the Early Solar System

    NASA Technical Reports Server (NTRS)

    Cook, Jamie Elsila

    2011-01-01

    The field of astrochemistry investigates the origin of the chemicals necessary for the formation of life. Astrochemists use remote observations, laboratory simulations, and analysis of extraterrestrial samples to understand the inventory of pre biotic chemicals present on the early Earth. Among the problems investigated by astrochemists is the origin of homo chirality in terrestrial life. Analysis of meteorites shows that they may have delivered an excess of L-amino acids to the Earth's surface, perhaps leading to homochirality.

  15. Interconnection network architectures based on integrated orbital angular momentum emitters

    NASA Astrophysics Data System (ADS)

    Scaffardi, Mirco; Zhang, Ning; Malik, Muhammad Nouman; Lazzeri, Emma; Klitis, Charalambos; Lavery, Martin; Sorel, Marc; Bogoni, Antonella

    2018-02-01

    Novel architectures for two-layer interconnection networks based on concentric OAM emitters are presented. A scalability analysis is done in terms of devices characteristics, power budget and optical signal to noise ratio by exploiting experimentally measured parameters. The analysis shows that by exploiting optical amplifications, the proposed interconnection networks can support a number of ports higher than 100. The OAM crosstalk induced-penalty, evaluated through an experimental characterization, do not significantly affect the interconnection network performance.

  16. Combining Static Analysis and Model Checking for Software Analysis

    NASA Technical Reports Server (NTRS)

    Brat, Guillaume; Visser, Willem; Clancy, Daniel (Technical Monitor)

    2003-01-01

    We present an iterative technique in which model checking and static analysis are combined to verify large software systems. The role of the static analysis is to compute partial order information which the model checker uses to reduce the state space. During exploration, the model checker also computes aliasing information that it gives to the static analyzer which can then refine its analysis. The result of this refined analysis is then fed back to the model checker which updates its partial order reduction. At each step of this iterative process, the static analysis computes optimistic information which results in an unsafe reduction of the state space. However we show that the process converges to a fired point at which time the partial order information is safe and the whole state space is explored.

  17. [Reliability and validity of the Braden Scale for predicting pressure sore risk].

    PubMed

    Boes, C

    2000-12-01

    For more accurate and objective pressure sore risk assessment various risk assessment tools were developed mainly in the USA and Great Britain. The Braden Scale for Predicting Pressure Sore Risk is one such example. By means of a literature analysis of German and English texts referring to the Braden Scale the scientific control criteria reliability and validity will be traced and consequences for application of the scale in Germany will be demonstrated. Analysis of 4 reliability studies shows an exclusive focus on interrater reliability. Further, even though examination of 19 validity studies occurs in many different settings, such examination is limited to the criteria sensitivity and specificity (accuracy). The range of sensitivity and specificity level is 35-100%. The recommended cut off points rank in the field of 10 to 19 points. The studies prove to be not comparable with each other. Furthermore, distortions in these studies can be found which affect accuracy of the scale. The results of the here presented analysis show an insufficient proof for reliability and validity in the American studies. In Germany, the Braden scale has not yet been tested under scientific criteria. Such testing is needed before using the scale in different German settings. During the course of such testing, construction and study procedures of the American studies can be used as a basis as can the problems be identified in the analysis presented below.

  18. Towards Scalable Deep Learning via I/O Analysis and Optimization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pumma, Sarunya; Si, Min; Feng, Wu-Chun

    Deep learning systems have been growing in prominence as a way to automatically characterize objects, trends, and anomalies. Given the importance of deep learning systems, researchers have been investigating techniques to optimize such systems. An area of particular interest has been using large supercomputing systems to quickly generate effective deep learning networks: a phase often referred to as “training” of the deep learning neural network. As we scale existing deep learning frameworks—such as Caffe—on these large supercomputing systems, we notice that the parallelism can help improve the computation tremendously, leaving data I/O as the major bottleneck limiting the overall systemmore » scalability. In this paper, we first present a detailed analysis of the performance bottlenecks of Caffe on large supercomputing systems. Our analysis shows that the I/O subsystem of Caffe—LMDB—relies on memory-mapped I/O to access its database, which can be highly inefficient on large-scale systems because of its interaction with the process scheduling system and the network-based parallel filesystem. Based on this analysis, we then present LMDBIO, our optimized I/O plugin for Caffe that takes into account the data access pattern of Caffe in order to vastly improve I/O performance. Our experimental results show that LMDBIO can improve the overall execution time of Caffe by nearly 20-fold in some cases.« less

  19. Systematic review and meta-analysis of prognostic role of splenic vessels infiltration in resectable pancreatic cancer.

    PubMed

    Crippa, Stefano; Cirocchi, Roberto; Maisonneuve, Patrick; Partelli, Stefano; Pergolini, Ilaria; Tamburrino, Domenico; Aleotti, Francesca; Reni, Michele; Falconi, Massimo

    2018-01-01

    Identification of factors associated with dismal survival after surgery in resectable pancreatic ductal adenocarcinoma is important to select patients for neoadjuvant treatment. The present meta-analysis aimed to compare the results of distal pancreatectomy for resectable adenocarcinoma of the pancreatic body-tail with and without splenic vessels infiltration. A systematic search was performed of PubMed, Embase and the Cochrane Library in accordance with PRISMA guidelines. The inclusion criteria were studies including patients who underwent distal pancreatectomy for pancreatic cancer with or without splenic vessels infiltration. 5-year overall survival (OS) was the primary outcomes. Meta-analysis was carried out applying time-to-event method. Six articles with 423 patients were analysed. Patients with pathological splenic artery invasion had a worse survival compared with those without infiltration (Hazard ratio 1.76, 95% CI 1.36-2.28; P < 0.0001). A similar results was found when considering pathological splenic vessels infiltration, showing that survival was significantly poorer when splenic vein infiltration was present (Hazard ratio 1.51, 95% CI 1.19-1.93; P = 0.0009). This meta-analysis showed worse survival for patients with splenic vessels infiltration undergoing distal pancreatectomy for pancreatic cancer. Splenic vessels infiltration represents the stigmata of a more aggressive disease, although resectable. Copyright © 2017 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.

  20. Evaluation of Founding Members of the International Academy of Health Sciences Informatics (IAHSI) Based on Google Scholar and Scopus Parameters.

    PubMed

    Masic, Izet

    2017-12-01

    The International Academy of Health Sciences Informatics (IAHSI) is established by International Medical Informatics Association (IMIA) which is the world body for health and biomedical informatics. The Academy will serve as an honor society that recognizes expertise in biomedical and health informatics internationally. Academy membership will be one of the highest honors in the international field of biomedical and health informatics. To present scientometric analysis of founding members of the International Academy of Health Sciences Informatics, to evaluate members and their scientific rating. The work has an analytical character and presents analysis of the data obtained from the Google Scholar and Scopus database. Results are shown through number of cases, percentage and graphically. The analysis showed a significant correlation between the Academy and the country (continent) of origin of the academician. In IAHSI are mainly represented academics originating from Europe - 40 members (33,3%), North America - 39 members (32,5%), Asia - 20 members (16,6%), South America - 9 members (7,5%), Australia - 7 members (5,8%), while only 5 members or 4,16% come from Africa. Criteria for number of representatives of each continent to main academic communities are relatively questionable, as this analysis showed. Development of Health Sciences Informatics should be the main purpose, and it should be evenly distributed with slight deviations in number of representatives of each continent.

Top