Disaster Day! Integrating Speech Skills though Impromptu Group Research and Presentation

ERIC Educational Resources Information Center

Pruim, Douglas E.

2016-01-01

Courses: Disaster Day (DD) is a single-class activity designed for public speaking classrooms, but could also be applied to courses addressing small group communication. Objectives: DD integrates fundamental skills of the basic speech course, fosters participation through group work, and introduces new concepts and skills. By the end of the…

Especially for Teachers: Selected Documents on the Teaching of Science 1966-1981.

ERIC Educational Resources Information Center

Helgeson, Stanley, Comp.; And Others

Designed to supplement the day-to-day planning, teaching, and evaluation activities of science teachers at all educational levels, this compilation contains over 900 resumes of practitioner-oriented documents announced in "Resources in Education" (RIE) between 1966 and 1981. The resumes are presented under these headings: (1) elementary…

Creating a Successful Leadership Style: Principles of Personal Strategic Planning

ERIC Educational Resources Information Center

Bonnici, Charles A.

2011-01-01

"Creating a Successful Leadership Style" gives practical applications supported by real experiences. It presents the actual situations a principal or assistant principal faces on a day-to-day basis and provides strategies to address them. These strategies derive from a leadership style that is people oriented and designed to elicit positive…

Programs for Infants and Young Children. Part IV: Facilities and Equipment.

ERIC Educational Resources Information Center

Sale, June

This manual is designed to facilitate planning for day care center facilities. Goals and principles of day care are discussed in relation to programs for infants, toddlers, and preschoolers with special attention to staff, parents, and community. Suggestions are presented for indoor and outdoor planning for such topics as equipment, supplies,…

Food Sanitation and Safety Self-assessment Instrument for Family Day-Care Homes.

ERIC Educational Resources Information Center

1990

This self-assessment instrument for family day care providers is designed to help caregivers provide safe food to children. The eight sections of the instrument, presented in checklist format, concern: (1) personal hygiene; (2) purchasing and inspecting of food; (3) food storage; (4) kitchen equipment; (5) food preparation; (6) infant food…

Process of videotape making: presentation design, software, and hardware

NASA Astrophysics Data System (ADS)

Dickinson, Robert R.; Brady, Dan R.; Bennison, Tim; Burns, Thomas; Pines, Sheldon

1991-06-01

The use of technical video tape presentations for communicating abstractions of complex data is now becoming commonplace. While the use of video tapes in the day-to-day work of scientists and engineers is still in its infancy, their use as applications oriented conferences is now growing rapidly. Despite these advancements, there is still very little that is written down about the process of making technical videotapes. For printed media, different presentation styles are well known for categories such as results reports, executive summary reports, and technical papers and articles. In this paper, the authors present ideas on the topic of technical videotape presentation design in a format that is worth referring to. They have started to document the ways in which the experience of media specialist, teaching professionals, and character animators can be applied to scientific animation. Software and hardware considerations are also discussed. For this portion, distinctions are drawn between the software and hardware required for computer animation (frame at a time) productions, and live recorded interaction with a computer graphics display.

Leveraging Information Technology. Track II: Innovative Management.

ERIC Educational Resources Information Center

CAUSE, Boulder, CO.

Seven papers from the 1987 CAUSE conference's Track II, Innovative Management, are presented. They include: "Is This Creative, or What!" (Kenneth C. Blythe); "Joint Application Design: Can a User Committee Design a System in Four Days?" (Diane Kent, David Smithers); "Making It Happen without Appropriation" (Robert E.…

Cassini-Huygens maneuver automation for navigation

NASA Technical Reports Server (NTRS)

Goodson, Troy; Attiyah, Amy; Buffington, Brent; Hahn, Yungsun; Pojman, Joan; Stavert, Bob; Strange, Nathan; Stumpf, Paul; Wagner, Sean; Wolff, Peter;

Effect of curing condition on the concrete moisture retention and its shielding implication for the design of fusion facilities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, S.; Chang, J.; Amin, S.

1981-01-01

Teste were conducted to determine the moisture retention for the 0.5 wt% borated concrete under three curing conditions. The three curing conditions are (1) curing at 100% relative humidity for a 28-day period at 21/degree/C, (2) curing at 100% relative humidity for a 7-day period, then at air-dry 50% relative humidity for the remaining 28-day curing period at 21/degree/C, and (3) curing at 100% relative humidity for a period of 7 days and then curing at air-dry 20% relative humidity for the remaining curing period at 21/degree/C. The concrete shielding curves are presented for several mositure contents. The results shouldmore » be helpful to assist the design of a cost effective concrete shield for fusion facilities.« less

The National Visitor Use Monitoring methodology and final results for round 1

Treesearch

S.J. Zarnoch; E.M. White; D.B.K. English; Susan M. Kocis; Ross Arnold

2011-01-01

A nationwide, systematic monitoring process has been developed to provide improved estimates of recreation visitation on National Forest System lands. Methodology is presented to provide estimates of site visits and national forest visits based on an onsite sampling design of site-days and last-exiting recreationists. Stratification of the site days, based on site type...

Inservice Training Seminar for the Driver Licensing Administrative Hearing Officer. Participant's Manual.

ERIC Educational Resources Information Center

National Highway Traffic Safety Administration (DOT), Washington, DC.

For use by trainees, this guide is the third of three designed for a two-day inservice training seminar for driver licensing administrative hearing officers. Participant's schedule information and materials are presented in three sections. The first includes the seminar agenda. Day 1 encompasses six units: (1) introduction, (2) the highway safety…

Alternative Federal Day Care Strategies for the 1970's. (Excerpts from the Final Report).

ERIC Educational Resources Information Center

Todd, Sheldon P.

This report discusses federal government support of day care services. Two alternatives are presented: (1) services designed, regulated and funded by a central agency, and (2) services provided through a free market industry in which decisions about regulations and care would be made by consumers, with only minimal central regulation. The market…

Supreme Civics: An Interview with Justice Sandra Day O'Connor

ERIC Educational Resources Information Center

Kinney, Patti

2011-01-01

This article presents an interview with Justice Sandra Day O'Connor. Justice O'Connor is the driving force behind iCivics, a nonprofit organization designed to increase students' knowledge of civics through interactive computer games that focus on history, laws, and government. In the interview, Justice O'Connor talks about the lack of civics…

Roll Call Questions To Enhance In-Class Presentations.

ERIC Educational Resources Information Center

Wiethoff, Carolyn

This paper outlines an activity which is designed to make students comfortable speaking in the classroom environment. The paper states that, used properly, the activity is also an introduction to each day's course topic, and it encourages students to think about and report their own life experiences that illustrate a core construct from the day's…

A Curriculum Guide for Inservice Education of Group Day Care and Nursery School Personnel.

ERIC Educational Resources Information Center

Thielges, Iva; Andersen, Rose

This curriculum guide outlines 10 inservice training courses for group day care and nursery school personnel. Each course outline presents a list of learning experiences and related resources from which the instructor can choose to meet the needs of his/her students. Materials are designed to meet the Minnesota Department of Public Welfare…

Combined VSWIR/TIR Products Overview: Issues and Examples

NASA Technical Reports Server (NTRS)

Knox, Robert G.

2010-01-01

The presentation provides a summary of VSWIR data collected at 19-day intervals for most areas. TIR data was collected both day and night on a 5-day cycle (more frequently at higher latitudes), the TIR swath is four times as wide as VSWIR, and the 5-day orbit repeat is approximate. Topics include nested swath geometry for reference point design and coverage simulations for sample FLUXNET tower sites. Other points examined include variation in latitude for revisit frequency, overpass times, and TIR overlap geometry and timing between VSWIR data collections.

Outdoor Education Guide-Handbook, Waukesha Public Schools.

ERIC Educational Resources Information Center

Vitale, Joseph A.

Designed by the Waukesha Public Schools (Wisconsin) specifically for an elementary level three-day camping trip at Camp Phantom Lake, this outdoor education guide presents some activities which suggest adaptation. Activity directions, plans, worksheets, evaluation sheets, and illustrations are presented in sequential order for the following…

National History Day Contest Guide.

ERIC Educational Resources Information Center

National History Day, Inc., Cleveland, OH.

The guide presents an overview of a national contest designed to make history come alive to students in grades 6 through 12 through imaginative projects, original performances, media presentations, and papers. Students submit their entries into contests in which they are judged by historians, educators, and other experienced professionals.…

Curricular Content for Pupils' Mental Health

ERIC Educational Resources Information Center

Ebadi, Seyed Hossein; Keshtiaray, Narges; Aghaei, Asghar; Yousefy, Alireza

2016-01-01

Present-day curricular designs have to take the pupils' psychological needs in account, thus becoming melodies of mental health and happiness for the next generation. Emphasizing the findings from previous investigations using the research synthesis methodology, the present study has been conducted aiming at achieving some integrative knowledge…

Stroke Risk After Non-Stroke ED Dizziness Presentations: A Population-Based Cohort Study

PubMed Central

Kerber, Kevin A.; Zahuranec, Darin B.; Brown, Devin L.; Meurer, William J.; Burke, James F.; Smith, Melinda A.; Lisabeth, Lynda D.; Fendrick, A. Mark; McLaughlin, Thomas; Morgenstern, Lewis B.

2014-01-01

Objective Acute stroke is a serious concern in Emergency Department (ED) dizziness presentations. Prior studies, however, suggest that stroke is actually an unlikely cause of these presentations. Lacking are data on short- and long-term follow-up from population-based studies to establish stroke risk after presumed non-stroke ED dizziness presentations. Methods From 5/8/2011 to 5/7/2012, patients ≥ 45 years of age presenting to EDs in Nueces County, Texas, with dizziness, vertigo, or imbalance were identified, excluding those with stroke as the initial diagnosis. Stroke events after the ED presentation up to 10/2/2012 were determined using the Brain Attack Surveillance in Corpus Christi (BASIC) study, which uses rigorous surveillance and neurologist validation. Cumulative stroke risk was calculated using Kaplan-Meier estimates. Results 1,245 patients were followed for a median of 347 days (IQR 230- 436 days). Median age was 61.9 years (IQR, 53.8-74.0 years). After the ED visit, fifteen patients (1.2%) had a stroke. Stroke risk was 0.48% (95% CI, 0.22%-1.07%) at 2 days; 0.48% (95% CI, 0.22%-1.07%) at 7 days; 0.56% (95% CI, 0.27%-1.18%) at 30 days; 0.56% (95% CI, 0.27%-1.18%) at 90 days; and 1.42% (95% CI, 0.85%-2.36%) at 12 months. Interpretation Using rigorous case ascertainment and outcome assessment in a population-based design, we found that the risk of stroke after presumed non-stroke ED dizziness presentations is very low, supporting a non-stroke etiology to the overwhelming majority of original events. High-risk subgroups likely exist, however, because most of the 90-day stroke risk occurred within 2-days. Vascular risk stratification was insufficient to identify these cases. PMID:24788511

Mobile Applications Improve Quality of Life on Citizens with Disorientation: The 'NeverLost App' Paradigm.

PubMed

Fotiou, Sotirios; Vlamos, Panayiotis

2017-01-01

Mobile technology has been evolved as an important tool in healthcare. Mobile applications are being designed in order to assist patients in their everyday life and also to play a vital role on the improvement of their everyday activities and quality of life. Meanwhile students use advanced techniques in order to design and implement high quality applications that aim to introduce them to the advantages of the mobile technology. In this paper we present the steps for the creation of the application NeverLost that was inspired, designed, created and tested by students of the Secondary Education. NeverLost is an Android application that helps individuals (mainly children) with disabilities, as well as older patients with lack of orientation manage their day-to-day activities. A research of the general benefits that students using this app is presented, as well as their future proposals for the evolution of the app in other aspects of healthcare and quality of life of senior citizens or patients with neurodegenerative diseases.

Helium refrigeration systems for super-conducting accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ganni, V.

Many of the present day accelerators are based on superconducting technology which requires 4.5-K or 2-K helium refrigeration systems. These systems utilize superconducting radio frequency (SRF) cavities and/or superconducting magnets which are packaged into vacuum vessels known as cryo-modules (CM’s). Many of the present day accelerators are optimized to operate primarily at around 2-K, requiring specialized helium refrigeration systems which are cost intensive to produce and to operate. Some of the cryogenic refrigeration system design considerations for these challenging applications are discussed.

The Design of the CCCII and Its Application Considerations in Library Automation.

ERIC Educational Resources Information Center

Huang, Jack Kai-tung; And Others

This paper presents the major characteristics of the Chinese Character Code for Information Interchange (CCCII) and indicates its intended application for the interchange of Chinese information among computer systems and communication facilities, especially in library networks. It is considered sufficient for present day library applications,…

"i" Am Needed

ERIC Educational Resources Information Center

Scott, Paul

2010-01-01

The mysteries of mathematics are not easily revealed. Much of present day school mathematics is the product of years, sometimes centuries, of inquiring, wrestling and discovering by men of the highest intellect. The number "i" (designation for the square root of -1) is no exception. This article presents a lesson on the need for "i".

Two Year Community: Design and Components of a Two-Year College Interdisciplinary Field-Study Course

ERIC Educational Resources Information Center

Wolfe, Benjamin A.; Martin, Todd C.

2013-01-01

Interdisciplinary field study courses at 2-year colleges can provide an opportunity to enhance student learning. The authors present here an 11-day interdisciplinary field-study course designed for nonscience majors at a 2-year college. Using a theoretical learning framework that emphasizes cognitive and metacognitive gains, the field study…

Problem Solving and Engineering Design, Introducing Bachelor Students to Engineering Practice at K. U. Leuven

ERIC Educational Resources Information Center

Heylen, Christel; Smet, Marc; Buelens, Hermans; Sloten, Jos Vander

2007-01-01

A present-day engineer has a large scientific knowledge; he is a team-player, eloquent communicator and life-long learner. At the Katholieke Universiteit Leuven, the course "Problem Solving and Engineering Design" introduces engineering students from the first semester onwards into real engineering practice and teamwork. Working in small…

Overview of computational structural methods for modern military aircraft

NASA Technical Reports Server (NTRS)

Kudva, J. N.

1992-01-01

Computational structural methods are essential for designing modern military aircraft. This briefing deals with computational structural methods (CSM) currently used. First a brief summary of modern day aircraft structural design procedures is presented. Following this, several ongoing CSM related projects at Northrop are discussed. Finally, shortcomings in this area, future requirements, and summary remarks are given.

Katimavik Field Staff Manual = Katimavik Manuel du Personnel D'Encadrement. Revised Edition.

ERIC Educational Resources Information Center

OPCAN, Montreal (Quebec).

Based upon accumulated field staff experience from years past, the bilingual manual is designed to be used on both a day-to-day basis as needs present themselves and for long-term planning by staff of Katimavik, a nine-month volunteer community service and learning program for 17 to 21-year-old Canadian youth. The manual is divided into three…

Industry-Education: One Community

ERIC Educational Resources Information Center

Lee, Ivy, Jr.

1972-01-01

Contains text of a speech presented at one of eight 2-day regional forums which describes the activities of the Northern California Industry-Education Council, an organization designed to bring industry and education closer together. (SB)

Teaching experimental design.

PubMed

Fry, Derek J

2014-01-01

Awareness of poor design and published concerns over study quality stimulated the development of courses on experimental design intended to improve matters. This article describes some of the thinking behind these courses and how the topics can be presented in a variety of formats. The premises are that education in experimental design should be undertaken with an awareness of educational principles, of how adults learn, and of the particular topics in the subject that need emphasis. For those using laboratory animals, it should include ethical considerations, particularly severity issues, and accommodate learners not confident with mathematics. Basic principles, explanation of fully randomized, randomized block, and factorial designs, and discussion of how to size an experiment form the minimum set of topics. A problem-solving approach can help develop the skills of deciding what are correct experimental units and suitable controls in different experimental scenarios, identifying when an experiment has not been properly randomized or blinded, and selecting the most efficient design for particular experimental situations. Content, pace, and presentation should suit the audience and time available, and variety both within a presentation and in ways of interacting with those being taught is likely to be effective. Details are given of a three-day course based on these ideas, which has been rated informative, educational, and enjoyable, and can form a postgraduate module. It has oral presentations reinforced by group exercises and discussions based on realistic problems, and computer exercises which include some analysis. Other case studies consider a half-day format and a module for animal technicians. © The Author 2014. Published by Oxford University Press on behalf of the Institute for Laboratory Animal Research. All rights reserved. For permissions, please email: journals.permissions@oup.com.

The Space Infrared Interferometric Telescope (SPIRIT): The Mission Design Solution Space and the Art of the Possible

NASA Technical Reports Server (NTRS)

Leisawitz, David; Hyde, T. Tupper; Rinehart, Stephen A.; Weiss, Michael

2008-01-01

Although the Space Infrared Interferometric Telescope (SPIRIT) was studied as a candidate NASA Origins Probe mission, the real world presents a broader set of options, pressures, and constraints. Fundamentally, SPIRIT is a far-IR observatory for high-resolution imaging and spectroscopy designed to address a variety of compelling scientific questions. How do planetary systems form from protostellar disks, dousing some planets in water while leaving others dry? Where do planets form, and why are some ice giants while others are rocky? How did high-redshift galaxies form and merge to form the present-day population of galaxies? This paper takes a pragmatic look at the mission design solution space for SPIRIT, presents Probe-class and facility-class mission scenarios, and describes optional design changes. The costs and benefits of various mission design alternatives are roughly evaluated, giving a basis for further study and to serve as guidance to policy makers.

A strategy for involving on-campus and distance students in a nursing research course.

PubMed

Shuster, George F; Learn, Cheryl Demerth; Duncan, Robert

2003-01-01

Teaching research at the undergraduate level can be a challenge. This is particularly true for distance education courses, in which students often feel isolated from each other and from faculty. Faculty teaching on-campus and distance education research courses designed a student research project and a method for bringing distance and on-campus students together to present their research findings. By actively engaging students in the research process and providing an on-campus research day for the presentation of student posters (Year 1) and research papers (Year 2), course faculty were able to achieve their two goals of directly involving students in the nursing research process and creating a greater student sense of belonging within the college learning community. Statistical analysis of an evaluation survey among on-site and off-site registered nurse to bachelor of science in nursing students indicated both groups ranked the Year 1 poster research day as good to very good. Students attending the Year 2 research day, where they presented papers, ranked the day as good. Statistical analysis indicated a significant difference between the two research days, with a clear student preference for posters. Students valued their active participation in the research process and the opportunity to get together and present their work. However, students clearly preferred a poster presentation format to presenting their findings as a research paper.

Comparative Review of UK-USA Industry-University Relationships

ERIC Educational Resources Information Center

Decter, Moira H.

2009-01-01

Purpose: The purpose of this paper is to explore significant historical changes, legislation and policy in the UK and USA from the 1960s to present day relating to university-industry relationships. Design/methodology/approach: The paper presents a review of papers, reports and policy documents from the UK and USA drawing comparisons of…

The design of common aperture and multi-band optical system based on day light telescope

NASA Astrophysics Data System (ADS)

Chen, Jiao; Wang, Ling; Zhang, Bo; Teng, Guoqi; Wang, Meng

2017-02-01

As the development of electro-optical weapon system, the technique of common path and multi-sensor are used popular, and becoming a trend. According to the requirement of miniaturization and lightweight for electro-optical stabilized sighting system, a day light telescope/television viewing-aim system/ laser ranger has been designed in this thesis, which has common aperture. Thus integration scheme of multi-band and common aperture has been adopted. A day light telescope has been presented, which magnification is 8, field of view is 6°, and distance of exit pupil is more than 20mm. For 1/3" CCD, television viewing-aim system which has 156mm focal length, has been completed. In addition, laser ranging system has been designed, with 10km raging distance. This paper outlines its principle which used day light telescope as optical reference of correcting the optical axis. Besides, by means of shared objective, reserved image with inverting prism and coating beam-splitting film on the inclined plane of the cube prism, the system has been applied to electro-optical weapon system, with high-resolution of imaging and high-precision ranging.

Institutional factors in resource recovery co-disposal demonstration project, Middlesex County, New Jersey, Spring 1980 - Summer 1981

NASA Astrophysics Data System (ADS)

McCarthy, R. M.

1982-02-01

A proposal to provide 1200 tons per day of solid waste disposal combined with 200 tons per day of sludge disposal was presented. The prospects for codisposal in Middlesex County were analyzed. Technically, codisposal was possible, however, it lacked a proven track record. Proposal for a resource recovery plant to be designed, built, and operated was acknowledged as consistent with County planning.

Dancing Eye Syndrome associated with spontaneous recovery and normal neurodevelopment.

PubMed

Ki Pang, K; Lynch, Bryan J; Osborne, John P; Pike, Michael G

2010-03-01

Five patients with spontaneously recovering Dancing Eye Syndrome/Opsoclonus Myoclonus Syndrome are described. Age at presentation ranged from 4 to 19 months. Four had symptoms of fever and a coryzal illness within days to a few weeks prior to the onset. One of the 4 also had varicella zoster 4 weeks before presentation. All had opsoclonus, myoclonus/ataxia and irritability. Associated infective agents identified were Coxsackie virus and rotavirus. Spontaneous improvement of symptoms started within 9 days of presentation and total duration of illness ranged from 10 to 24 days. Developmental progress at follow-up was normal in all cases. A range of immunomodulatory therapies have been advocated for the treatment of Dancing Eye Syndrome/Opsoclonus Myoclonus Syndrome. However, in some children, early spontaneous recovery may occur, an observation which should be borne in mind when designing therapeutic trials in this condition. 2009 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

Aqueous Alteration of Basaltic Glass Under a Simulated Mars Atmosphere

NASA Technical Reports Server (NTRS)

Bullock, M. A.; Moore, J. M.

2005-01-01

For the past several years we have been performing experiments designed to produce brines under Mars-simulated conditions. Previously, we had generated and analyzed Mars-analog brines by allowing a mixture of minerals derived from SNC mineralogy to soak in pure water under a synthetic current-Mars atmosphere and under a gas similar to the present Mars atmosphere but with added acidic gases. The latest version of these experiments incubates basaltic glass, obtained from recent Kilauea flows (Mother's Day flow in December 2002), in pure water under a present-day Mars analog atmosphere at 25 C. This abstract and our presentation will discuss the composition of these Mars-analog brines and implications for Mars surface chemistry.

The innovation catalysts.

PubMed

Martin, Roger L

2011-06-01

A few years ago the software development company Intuit realized that it needed a new approach to galvanizing customers. The company's Net Promoter Score was faltering, and customer recommendations of new products were especially disappointing. Intuit decided to hold a two-day, off-site meeting for the company's top 300 managers with a focus on the role of design in innovation. One of the days was dedicated to a program called Design for Delight. The centerpiece of the day was a PowerPoint presentation by Intuit founder Scott Cook, who realized midway through that he was no Steve Jobs: The managers listened dutifully, but there was little energy in the room. By contrast, a subsequent exercise in which the participants worked through a design challenge by creating prototypes, getting feedback, iterating, and refining, had them mesmerized. The eventual result was the creation of a team of nine design-thinking coaches--"innovation catalysts"--from across Intuit who were made available to help any work group create prototypes, run experiments, and learn from customers. The process includes a "painstorm" (to determine the customer's greatest pain point), a "soljam" (to generate and then winnow possible solutions), and a "code-jam" (to write code "good enough" to take to customers within two weeks). Design for Delight has enabled employees throughout Intuit to move from satisfying customers to delighting them.

Stroke risk after nonstroke emergency department dizziness presentations: a population-based cohort study.

PubMed

Kerber, Kevin A; Zahuranec, Darin B; Brown, Devin L; Meurer, William J; Burke, James F; Smith, Melinda A; Lisabeth, Lynda D; Fendrick, A Mark; McLaughlin, Thomas; Morgenstern, Lewis B

2014-06-01

Acute stroke is a serious concern in emergency department (ED) dizziness presentations. Prior studies, however, suggest that stroke is actually an unlikely cause of these presentations. Lacking are data on short- and long-term follow-up from population-based studies to establish stroke risk after presumed nonstroke ED dizziness presentations. From May 8, 2011 to May 7, 2012, patients ≥45 years of age presenting to EDs in Nueces County, Texas, with dizziness, vertigo, or imbalance were identified, excluding those with stroke as the initial diagnosis. Stroke events after the ED presentation up to October 2, 2012 were determined using the BASIC (Brain Attack Surveillance in Corpus Christi) study, which uses rigorous surveillance and neurologist validation. Cumulative stroke risk was calculated using Kaplan-Meier estimates. A total of 1,245 patients were followed for a median of 347 days (interquartile range [IQR] = 230-436 days). Median age was 61.9 years (IQR = 53.8-74.0 years). After the ED visit, 15 patients (1.2%) had a stroke. Stroke risk was 0.48% (95% confidence interval [CI] = 0.22-1.07%) at 2 days, 0.48% (95% CI = 0.22-1.07%) at 7 days, 0.56% (95% CI = 0.27-1.18%) at 30 days, 0.56% (95% CI = 0.27-1.18%) at 90 days, and 1.42% (95% CI = 0.85-2.36%) at 12 months. Using rigorous case ascertainment and outcome assessment in a population-based design, we found that the risk of stroke after presumed nonstroke ED dizziness presentations is very low, supporting a nonstroke etiology to the overwhelming majority of original events. High-risk subgroups likely exist, however, because most of the 90-day stroke risk occurred within 2 days. Vascular risk stratification was insufficient to identify these cases. © 2014 American Neurological Association.

Training Manual: NSDC's Standards for Staff Development [CD-ROM

ERIC Educational Resources Information Center

Roy, Patricia

2006-01-01

This 60-page guidebook presents a plan for a one-day workshop to introduce NSDC's standards to educators. The sessions are designed to encourage participant involvement to develop greater understanding of the standards. The slide presentation plus materials needed to conduct activities are included as PDF files on a CD-ROM. This guidebook may be…

Gas-analytic measurement complexes of Baikal atmospheric-limnological observatory

NASA Astrophysics Data System (ADS)

Pestunov, D. A.; Shamrin, A. M.; Shmargunov, V. P.; Panchenko, M. V.

2015-11-01

The paper presents the present-day structure of stationary and mobile hardware-software gas-analytical complexes of Baikal atmospheric-limnological observatory (BALO) Siberian Branch Russian Academy of Sciences (SB RAS), designed to study the processes of gas exchange of carbon-containing gases in the "atmosphere-water" system, which are constantly updated to include new measuring and auxiliary instrumentation.

Effects of Cigarette Smoking on Body Weight, Energy Expenditure, Appetite and Endocrine Function

DTIC Science & Technology

1982-03-01

the present study diet was kept constant iu both caloric content and composition and an on-off-on design was employed to evaluate the independent...plasma substrate concentrations, appetite and metabolic rate were thus assessed independently of change in caloric intake. Only small, statistically...day control period (smoking control, SC period), the subjects smoked their usual pack a day of cigarettes while taking a diet of controlled composition

Sky Sculpture.

ERIC Educational Resources Information Center

Woody, Howard

1980-01-01

Described is a five-day workshop in the new environmental art form of sky sculpture, which was presented at Wingfield High School in Jackson, Mississippi. Included are daily activities and the design considerations faced by students when planning their balloon creations for flight. (SJL)

The planet Saturn (1970)

NASA Technical Reports Server (NTRS)

1972-01-01

The present-day knowledge on Saturn and its environment are described for designers of spacecraft which are to encounter and investigate the planet. The discussion includes physical properties of the planet, gravitational field, magnetic and electric fields, electromagnetic radiation, satellites and meteoroids, the ring system, charged particles, atmospheric composition and structure, and clouds and atmospheric motions. The environmental factors which have pertinence to spacecraft design criteria are also discussed.

Spaceship Discovery's Crew and Cargo Lander Module Designs for Human Exploration of Mars

NASA Astrophysics Data System (ADS)

Benton, Mark G.

2008-01-01

The Spaceship Discovery design was first presented at STAIF 2006. This conceptual design space vehicle architecture for human solar system exploration includes two types of Mars exploration lander modules: A piloted crew lander, designated Lander Module 2 (LM2), and an autonomous cargo lander, designated Lander Module 3 (LM3). The LM2 and LM3 designs were first presented at AIAA Space 2007. The LM2 and LM3 concepts have recently been extensively redesigned. The specific objective of this paper is to present these revised designs. The LM2 and LM3 landers are based on a common design that can be configured to carry either crew or cargo. They utilize a combination of aerodynamic reentry, parachutes, and propulsive braking to decelerate from orbital velocity to a soft landing. The LM2 crew lander provides two-way transportation for a nominal three-person crew between Mars orbit and the surface, and provides life support for a 30-day contingency mission. It contains an ascent section to return the crew to orbit after completion of surface operations. The LM3 cargo lander provides one-way, autonomous transportation of cargo from Mars orbit to the surface and can be configured to carry a mix of consumables and equipment, or equipment only. Lander service life and endurance is based on the Spaceship Discovery conjunction-class Design Reference Mission 2. The LM3 is designed to extend the surface stay for three crew members in an LM2 crew lander such that two sets of crew and cargo landers enable human exploration of the surface for the bulk of the 454 day wait time at Mars, in two shifts of three crew members each. Design requirements, mission profiles, mass properties, performance data, and configuration layouts are presented for the LM2 crew and LM3 cargo landers. These lander designs are a proposed solution to the problem of safely transporting a human crew from Mars orbit to the surface, sustaining them for extended periods of time on the surface, and returning them safely to orbit. They are based on reliable and proven technology and build on an extensive heritage of successful unmanned probes. Safety, redundancy, and abort and rescue capabilities are stressed in the design and operations concepts. The designs share many common features, hardware, subsystems, and flight control modes to reduce development cost.

Raising awareness of the importance of engineering protections against floods with "Flood-o-poly" v.2

NASA Astrophysics Data System (ADS)

Valyrakis, Manousos; Cheng, Ming

2017-04-01

This study presents the results of a survey focusing on the use of a new fit for purpose designed city in a sand-box model, namely "Flood-o-poly" version 2, which is building on the success of the previous model. "Flood-o-poly" has been successfully presented to thousands of students of all ages in the School of Engineering Open days (University of Glasgow), Widening Participation, Glasgow Science Festival, Glasgow Science Museum and Engineering Hydraulics classes and Design projects, over the last four years. The new design involves a new and extended 3D scaled model that accurately replicates the topography of a city along with its rivers, towards demonstrating the impacts of flooding (induced artificially in the scaled physical model via the use of small water pumps). "Flood-o-poly" is a highly visual and well popularized engineering outreach project (developed from the applicant at the University of Glasgow), which has already been extensively used to showcase the detrimental impacts of flooding, for both the natural ecosystems and the build infrastructure alike (see https://twitter.com/WaterEngLab/status/758270564561784832 on Twitter and https://youtu.be/H5oThT6QaTc on Youtube). This involves a highly interactive session where the students simulate the scenarios of "urbanization" (by placing more buildings on the flood-planes) and "climate change" where more extreme flow rates have to be routed through the river. The project demonstrates how this design can benefit the cohorts of the 3rd and 4rth year Civil Engineering undergraduate students, the students attending the School's Open days, Widening Participation Days, Glasgow Science Festival and Glasgow Science Museum events. "Flood-o-poly" focuses on personalizing the student experience with regard to flood impacts and promotes the need for resilient and sustainable flood protection designs. Further, using novel presentation and student-centered technologies, the students are given a truly unique experience and appreciate engineering principles and design approaches, as well as appreciate contemporary and optimal (under certain realistic constraints) flood protections that can be used to protect "Flood-o-poly" from extreme hydrologic events.

New Mexico climate manual: solar and weather data. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morris, W.S.; Haggard, K.W

This manual contains extensive solar and weather data for the state of New Mexico in tabular, map, and graphic formats. It is particularly relevant to design of energy efficient buildings and renewable energy systems, but is also broad enough to provide useful information to many other disciplines. Maps of the state show monthly values of insolation for horizontal, south-facing latitude-tilted and vertical surfaces, as well as mean temperatures. Climatic summaries given for 63 sites include monthly temperature and precipitation data as well as heating/cooling degree-days and design temperatures. For nine locations (Albuquerque, Clayton, Farmington, Los Alamos, Roswell, T or C,more » Tucumcari, Zuni, and El Paso, Texas) most of the following comprehensive data sets are also presented: design temperatures with mean coincident wet bulb and wind values; HDD/CDD values to 12 base temperatures; day/night wind data; typical and clear-day values of incident and transmitted solar radiation for 97 orientations and tilts; and temperature distribution data in 2/sup 0/F bins for six daily time periods. Extensive explanatory text with referencing to the data is provided.« less

Lunar base thermal management/power system analysis and design

NASA Technical Reports Server (NTRS)

Mcghee, Jerry R.

1992-01-01

A compilation of several lunar surface thermal management and power system studies completed under contract and IR&D is presented. The work includes analysis and preliminary design of all major components of an integrated thermal management system, including loads determination, active internal acquisition and transport equipment, external transport systems (active and passive), passive insulation, solar shielding, and a range of lunar surface radiator concepts. Several computer codes were utilized in support of this study, including RADSIM to calculate radiation exchange factors and view factors, RADIATOR (developed in-house) for heat rejection system sizing and performance analysis over a lunar day, SURPWER for power system sizing, and CRYSTORE for cryogenic system performance predictions. Although much of the work was performed in support of lunar rover studies, any or all of the results can be applied to a range of surface applications. Output data include thermal loads summaries, subsystem performance data, mass, and volume estimates (where applicable), integrated and worst-case lunar day radiator size/mass and effective sink temperatures for several concepts (shielded and unshielded), and external transport system performance estimates for both single and two-phase (heat pumped) transport loops. Several advanced radiator concepts are presented, along with brief assessments of possible system benefits and potential drawbacks. System point designs are presented for several cases, executed in support of the contract and IR&D studies, although the parametric nature of the analysis is stressed to illustrate applicability of the analysis procedure to a wide variety of lunar surface systems. The reference configuration(s) derived from the various studies will be presented along with supporting criteria. A preliminary design will also be presented for the reference basing scenario, including qualitative data regarding TPS concerns and issues.

"Fab 13": The Learning Factory.

ERIC Educational Resources Information Center

Crooks, Steven M.; Eucker, Tom R.

2001-01-01

Describes how situated learning theory was employed in the design of Fab 13, a four-day simulation-based learning experience for manufacturing professionals at Intel Corporation. Presents a conceptual framework for understanding situated learning and discusses context, content, anchored instruction, facilitation, scaffolding, collaborating,…

COPE Method Implementation Program to Reduce Communication Apprehension Level in Full Day Yunior High School Students

NASA Astrophysics Data System (ADS)

Prasetyo, A. R.

2017-02-01

This study was aimed to explore the effect of COPE method to reduce communication apprehension level of students in Early Adolescence who become Full Day Junior High School students. Full Day Junior High School students, especially in Surabaya coastal area, have more demands to develop the communication aspects such as group discussions and presentations and extracurricular activities. Higher demands to develop such aspects of communication may cause them to experience communication apprehension. The subject was Full Day School students totaling 31 students. The design of the research was experimental design. The experimental method used was a non-randomized pretest posttest control group design and purposive sampling was also used. COPE method is a process that consists of four main stages where people are trying to deal with and control of stressful situations as a result of the problem being faced by conducting cognitive and behavioral changes. Four main stages COPE method is Calming the nervous system, Originating an imaginative plan, Persisting in the face of obstacles and failure, and Evaluating and adjusting the plan. Results of quantitative analysis based on U-Mann Whitney Test shows significant effect on the COPE Method to decrease anxiety levels of communication (0.000 <0.005).

An Eclectic Look At Viewing Station Design

NASA Astrophysics Data System (ADS)

Horii, Steven C.; Horii, Howard N.; Kowalski, Philip

1988-06-01

Imaging workstations for radiology would be used by radiologists for a number of hours each day. Such long use demands a good ergonomic design of the workstation in order to avoid user fatigue and frustration. The film-and-viewbox methods presently in use have evolved over the years since radiography became a diagnostic tool. The result of this evolution is that, despite the problems of film, the ergonomics of film reading and reporting is quite mature. This paper will use a somewhat lighthearted look at workstation design using the ideas of well-known architects and designers to illustrate points which should be considered when implementing electronic viewing systems. Examples will also be drawn from non-radiologic environments in which the user is presented with visual information for his or her integration.

Fifty Years of Observing Hardware and Human Behavior

NASA Technical Reports Server (NTRS)

McMann, Joe

2011-01-01

During this half-day workshop, Joe McMann presented the lessons learned during his 50 years of experience in both industry and government, which included all U.S. manned space programs, from Mercury to the ISS. He shared his thoughts about hardware and people and what he has learned from first-hand experience. Included were such topics as design, testing, design changes, development, failures, crew expectations, hardware, requirements, and meetings.

The Effects of Binge Drinking on College Students’ Next-Day Academic Test-Taking Performance and Mood State

PubMed Central

Howland, Jonathan; Rohsenow, Damaris J; Greece, Jacey A; Littlefield, Caroline A; Almeida, Alissa; Heeren, Timothy; Winter, Michael; Bliss, Caleb A.; Hunt, Sarah; Hermos, John

2010-01-01

Aim To assess the effects of binge drinking on students’ next-day academic test-taking performance. Design A placebo-controlled cross-over design with randomly assigned order of conditions. Participants were randomized to either alcoholic beverage (mean =.12 g% breath alcohol concentration [BrAC]) or placebo on the first night and then received the other beverage a week later. The next day, participants were assessed on test-taking, neurocognitive performance and mood state. Participants 193 college students (≥ 21 years) recruited from greater Boston. Setting The trial was conducted at the General Clinical Research Center at the Boston Medical Center. Measurements The Graduate Record Exams © (GREs) and a quiz on a lecture presented the previous day measured test-taking performance; the Neurobehavioral Evaluation System (NES3) and the Psychomotor Vigilance Test (PVT) measured neurocognitive performance; and, the Profile of Mood States (POMS) measured mood. Findings Test-taking performance was not affected the morning after alcohol administration, but mood state and attention/reaction time were. Conclusion Drinking to a level of .12 g% BrAC does not affect next-day test-taking performance, but does affect some neurocognitive measures and mood state. PMID:20403018

Royal jelly modulates oxidative stress and tissue injury in gamma irradiated male Wister Albino rats.

PubMed

Azab, Khaled Shaaban; Bashandy, Mohamed; Salem, Mahmoud; Ahmed, Osama; Tawfik, Zaki; Helal, Hamed

2011-06-01

Royal jelly is a nutritive secretion produced by the worker bees, rich in proteins, carbohydrates, vitamins and minerals. The present study was designed to determine the possible protective effects of royal jelly against radiation induced oxidative stress, hematological, biochemical and histological alterations in male Wister albino rats. Male Wister albino rats were exposed to a fractionated dose of gamma radiation (2 Gy every 3 days up to 8 Gy total doses). Royal jelly was administrated (g/Kg/day) by gavages 14 days before exposure to the 1(st) radiation fraction and the treatment was continued for 15 days after the 1(st) irradiation fraction till the end of the experiment. The rats were sacrificed 3(rd), equivalent to 3rd post 2nd irradiation fraction, and equivalent to 3rd day post last irradiation fraction. In the present study, gamma- irradiation induced hematological, biochemical and histological effects in male Wister albino rats. In royal jelly treated irradiated group, there was a noticeable decrease recorded in thiobarbituric reactive substances concentration when compared to γ-irradiated group. Also, the serum nitric oxide concentration was significantly improved. The administration of royal jelly to irradiated rats according to the current experimental design significantly ameliorates the changes induced in serum lipid profile. Moreover, in royal jelly treated irradiated group, there was a noticeable amelioration recorded in all hematological parameters along the three experimental intervals. The microscopic examination of cardiac muscle of royal jelly treated irradiated rats demonstrated structural amelioration, improved nuclei and normal features of capillaries and veins in endomysium when compared to gamma-irradiated rats. It was suggested that the biochemical, hematological and histological amelioration observed in royal jelly (g/Kg/day) treated irradiated rats might be due to the antioxidant capacity of royal jelly active constituents.

The First of March Gets the Seal of Approval.

ERIC Educational Resources Information Center

Tinney, Richard; And Others

1984-01-01

Presents background information on seals, legislation designed to protect them, activities related to seals and the fourth International Day of the Seal, and suggestions for field trips. Includes list of materials available from the Seal Rescue Fund with current costs. (JM)

Spaceborne VHSIC multiprocessor system for AI applications

NASA Technical Reports Server (NTRS)

Lum, Henry, Jr.; Shrobe, Howard E.; Aspinall, John G.

1988-01-01

A multiprocessor system, under design for space-station applications, makes use of the latest generation symbolic processor and packaging technology. The result will be a compact, space-qualified system two to three orders of magnitude more powerful than present-day symbolic processing systems.

[Toxoplasmosis in sick persons].

PubMed

Netrebko, I D

2002-01-01

A screening investigation was conducted designed to identify ill persons presenting with toxoplasmosis with the aid of an intracutaneous test with toxoplasmin and complement-fixing reaction with a dry toxoplasmic antigen. Toxoplasmosis was detected in those persons having lymphadenitis, therapeutical patients, women with aggravated obstetrical history having had spontaneous abortions and having given birth to sick children, patients with sluggish meningoencephalitis presenting with epileptoid and hypothalamic syndrome, polyneuritis, and patients with myopia, chorioretinitis and uveitis. Identification and treatment of toxoplasmic invasion constitutes a valid method of control of spontaneous abortions of toxoplasmic etiology. Detection in a timely fashion of toxoplasmic invasion in pregnant women and preventive treatment with two 5-day cycles of pirimetamin (0.025) twice a day and sulfodimezin (0.5) four times daily with a 10-day interval between the cycles has been found out to prevent toxoplasmosis affliction of the fetus.

Design of a home-based adaptive mixed reality rehabilitation system for stroke survivors.

PubMed

Baran, Michael; Lehrer, Nicole; Siwiak, Diana; Chen, Yinpeng; Duff, Margaret; Ingalls, Todd; Rikakis, Thanassis

2011-01-01

This paper presents the design of a home-based adaptive mixed reality system (HAMRR) for upper extremity stroke rehabilitation. The goal of HAMRR is to help restore motor function to chronic stroke survivors by providing an engaging long-term reaching task therapy at home. The system uses an intelligent adaptation scheme to create a continuously challenging and unique multi-year therapy experience. The therapy is overseen by a physical therapist, but day-to-day use of the system can be independently set up and completed by a stroke survivor. The HAMMR system tracks movement of the wrist and torso and provides real-time, post-trial, and post-set feedback to encourage the stroke survivor to self-assess his or her movement and engage in active learning of new movement strategies. The HAMRR system consists of a custom table, chair, and media center, and is designed to easily integrate into any home.

Design and evaluation of the computer-based training program Calcularis for enhancing numerical cognition

PubMed Central

Käser, Tanja; Baschera, Gian-Marco; Kohn, Juliane; Kucian, Karin; Richtmann, Verena; Grond, Ursina; Gross, Markus; von Aster, Michael

2013-01-01

This article presents the design and a first pilot evaluation of the computer-based training program Calcularis for children with developmental dyscalculia (DD) or difficulties in learning mathematics. The program has been designed according to insights on the typical and atypical development of mathematical abilities. The learning process is supported through multimodal cues, which encode different properties of numbers. To offer optimal learning conditions, a user model completes the program and allows flexible adaptation to a child's individual learning and knowledge profile. Thirty-two children with difficulties in learning mathematics completed the 6–12-weeks computer training. The children played the game for 20 min per day for 5 days a week. The training effects were evaluated using neuropsychological tests. Generally, children benefited significantly from the training regarding number representation and arithmetic operations. Furthermore, children liked to play with the program and reported that the training improved their mathematical abilities. PMID:23935586

Photovoltaic dryer with dual packed beds for drying medical herb

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abdel-Rehim, Z.S.; Fahmy, F.H.

1998-03-01

This work presents design and optimization of a cylindrical photovoltaic dryer with dual packed beds thermal energy storage for drying medical herb. The dryer is provided with electrical heater where the electrical energy is generated by using photovoltaic system. The electrical heater is designed and sized to realize continuous drying (day and night) to minimize the drying time. Two packed beds are used to fix the drying temperature in dryer during day and night. The main packed bed thermal energy storage is charged during the sunlight hours directly, to realize continued drying after sunset. An efficient PV dryer is devisedmore » to work under forced air created by air blower and heated by the electrical coils.« less

ARC-2008-ACD08-0199-004

NASA Image and Video Library

2008-09-04

Foton-M2 and Foton-M3 Mission description and summary of science results presented by Dr Richard Boyle The Foton-M3 spacecraft launched from Baikonur Cosmodrome (Kazakhstan) on Sept 14, 2007 and landed 12 days later approximately 130km south of Kustanay, Northern Kazakhstan. The Foton-me flight, following the 16-day Foto-M2 spaceflight (june 2005), represented a uique opportunity to re-fly and improve the Foton-M2 experiments. For Foton-Me, important improvements were made in hardware, experimental design and operational logistics.

ARC-2008-ACD08-0199-006

NASA Image and Video Library

2008-09-04

Foton-M2 and Foton-M3 Mission description and summary of science results presented by Dr. Eduardo Almeida The Foton-M3 spacecraft launched from Baikonur Cosmodrome (Kazakhstan) on Sept 14, 2007 and landed 12 days later approximately 130km south of Kustanay, Northern Kazakhstan. The Foton-me flight, following the 16-day Foto-M2 spaceflight (june 2005), represented a uique opportunity to re-fly and improve the Foton-M2 experiments. For Foton-Me, important improvements were made in hardware, experimental design and operational logistics.

ARC-2008-ACD08-0199-003

NASA Image and Video Library

2008-09-04

Foton-M2 and Foton-M3 Mission description and summary of science results presented by Mike Skidmore The Foton-M3 spacecraft launched from Baikonur Cosmodrome (Kazakhstan) on Sept 14, 2007 and landed 12 days later approximately 130km south of Kustanay, Northern Kazakhstan. The Foton-me flight, following the 16-day Foto-M2 spaceflight (june 2005), represented a uique opportunity to re-fly and improve the Foton-M2 experiments. For Foton-Me, important improvements were made in hardware, experimental design and operational logistics.

Speaking With Us.

ERIC Educational Resources Information Center

Yakima Valley Coll., WA.

An illustrated workbook containing exercises in speaking and writing skills designed for a beginning learner of English as a second language is presented. The workbook includes material on greetings, giving personal information, numbers, time, days of the week, holidays, body parts, health information, states of being, food, colors, clothing,…

The Hospice: An Integrated Bibliography.

ERIC Educational Resources Information Center

Bodine, George E.; Sobotor, William

This extensive bibliography of books and articles provides an interdisciplinary overview of present day terminal care and the hospice alternative. Designed to aid in the development and implementation of terminal care programs stressing palliative and supportive services for both patients and their families, the bibliography includes abstracts of…

What's in a Day? A Guide to Decomposing the Variance in Intensive Longitudinal Data

PubMed Central

de Haan-Rietdijk, Silvia; Kuppens, Peter; Hamaker, Ellen L.

2016-01-01

In recent years there has been a growing interest in the use of intensive longitudinal research designs to study within-person processes. Examples are studies that use experience sampling data and autoregressive modeling to investigate emotion dynamics and between-person differences therein. Such designs often involve multiple measurements per day and multiple days per person, and it is not clear how this nesting of the data should be accounted for: That is, should such data be considered as two-level data (which is common practice at this point), with occasions nested in persons, or as three-level data with beeps nested in days which are nested in persons. We show that a significance test of the day-level variance in an empty three-level model is not reliable when there is autocorrelation. Furthermore, we show that misspecifying the number of levels can lead to spurious or misleading findings, such as inflated variance or autoregression estimates. Throughout the paper we present instructions and R code for the implementation of the proposed models, which includes a novel three-level AR(1) model that estimates moment-to-moment inertia and day-to-day inertia. Based on our simulations we recommend model selection using autoregressive multilevel models in combination with the AIC. We illustrate this method using empirical emotion data from two independent samples, and discuss the implications and the relevance of the existence of a day level for the field. PMID:27378986

What's in a Day? A Guide to Decomposing the Variance in Intensive Longitudinal Data.

PubMed

de Haan-Rietdijk, Silvia; Kuppens, Peter; Hamaker, Ellen L

2016-01-01

In recent years there has been a growing interest in the use of intensive longitudinal research designs to study within-person processes. Examples are studies that use experience sampling data and autoregressive modeling to investigate emotion dynamics and between-person differences therein. Such designs often involve multiple measurements per day and multiple days per person, and it is not clear how this nesting of the data should be accounted for: That is, should such data be considered as two-level data (which is common practice at this point), with occasions nested in persons, or as three-level data with beeps nested in days which are nested in persons. We show that a significance test of the day-level variance in an empty three-level model is not reliable when there is autocorrelation. Furthermore, we show that misspecifying the number of levels can lead to spurious or misleading findings, such as inflated variance or autoregression estimates. Throughout the paper we present instructions and R code for the implementation of the proposed models, which includes a novel three-level AR(1) model that estimates moment-to-moment inertia and day-to-day inertia. Based on our simulations we recommend model selection using autoregressive multilevel models in combination with the AIC. We illustrate this method using empirical emotion data from two independent samples, and discuss the implications and the relevance of the existence of a day level for the field.

Photothermal camera port accessory for microscopic thermal diffusivity imaging

NASA Astrophysics Data System (ADS)

Escola, Facundo Zaldívar; Kunik, Darío; Mingolo, Nelly; Martínez, Oscar Eduardo

2016-06-01

The design of a scanning photothermal accessory is presented, which can be attached to the camera port of commercial microscopes to measure thermal diffusivity maps with micrometer resolution. The device is based on the thermal expansion recovery technique, which measures the defocusing of a probe beam due to the curvature induced by the local heat delivered by a focused pump beam. The beam delivery and collecting optics are built using optical fiber technology, resulting in a robust optical system that provides collinear pump and probe beams without any alignment adjustment necessary. The quasiconfocal configuration for the signal collection using the same optical fiber sets very restrictive conditions on the positioning and alignment of the optical components of the scanning unit, and a detailed discussion of the design equations is presented. The alignment procedure is carefully described, resulting in a system so robust and stable that no further alignment is necessary for the day-to-day use, becoming a tool that can be used for routine quality control, operated by a trained technician.

Behavioral Effects of Acclimatization To Restraint Protocol Used for Awake Animal Imaging

PubMed Central

Reed, Michael D.; Pira, Ashley S.; Febo, Marcelo

2013-01-01

Functional MRI of awake rats involves acclimatization to restraint to minimize motion. We designed a study to examine the effects of an acclimatization protocol (5 days of restraint, 60 minutes per day) on the emission of 22-kHz ultrasonic vocalizations and performance on a forced swim test (FST). Our results show that USV calls are reduced significantly by day 3, 4 and 5 of acclimatization. Although rats show less climbing activity (and more immobility) in FST on day 5 compared to the 1st day of restraint acclimatization, the difference is gone once animals are given a 2 week hiatus. Overall, we show that animals adapt to the restraint over the five day period, however, restraint may introduce confounding behavioral outcomes that may hinder the interpretation of results derived from awake rat imaging. The present data warrant further testing of the effects of MRI restraint on behavior. PMID:23562621

Aerodynamic design optimization of a fuel efficient high-performance, single-engine, business airplane

NASA Technical Reports Server (NTRS)

Holmes, B. J.

1980-01-01

A design study has been conducted to optimize a single-engine airplane for a high-performance cruise mission. The mission analyzed included a cruise speed of about 300 knots, a cruise range of about 1300 nautical miles, and a six-passenger payload (5340 N (1200 lb)). The purpose of the study is to investigate the combinations of wing design, engine, and operating altitude required for the mission. The results show that these mission performance characteristics can be achieved with fuel efficiencies competitive with present-day high-performance, single- and twin-engine, business airplanes. It is noted that relaxation of the present Federal Aviation Regulation, Part 23, stall-speed requirement for single-engine airplanes facilitates the optimization of the airplane for fuel efficiency.

Skylab Medical Experiments Altitude Test /SMEAT/ facility design and operation.

NASA Technical Reports Server (NTRS)

Hinners, A. H., Jr.; Correale, J. V.

1973-01-01

This paper presents the design approaches and test facility operation methods used to successfully accomplish a 56-day test for Skylab to permit evaluation of selected Skylab medical experiments in a ground test simulation of the Skylab environment with an astronaut crew. The systems designed for this test include the two-gas environmental control system, the fire suppression and detection system, equipment transfer lock, ground support equipment, safety systems, potable water system, waste management system, lighting and power system, television monitoring, communications and recreation systems, and food freezer.

Online Catalog Screen Displays. A Series of Discussions. Report of a Conference Sponsored by the Council on Library Resources (Austin, Texas, March 10-13, 1985).

ERIC Educational Resources Information Center

Williams, Joan Frye, Ed.

Papers presented and summaries of discussions at a 3-day conference which focused on screen displays for online catalogs are included in this report. Papers presented were: (1) "Suggested Guidelines for Screen Layouts and Design of Online Catalogs" (Joseph R. Matthews); (2) "Displays in Database Search Systems" (Fran Spigai);…

The unrealized potential for heavy balloon payloads

NASA Astrophysics Data System (ADS)

Winker, J. A.

1993-02-01

Knowing that properties of new polyethylene films are superior to previous types, one would believe that heavier payloads can now be safely carried. Some experimentation has already been done to verify that assumption. Future expectations are discussed. We believe that with present-day materials, and with only limited changes in design philosophies, maximum payload weights can be increased by 50 to 75% from presently accepted maxima.

Resolving the ambiguities: An industrial hygiene Indoor Air Quality (IAQ) symposium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gammage, R.B.

1995-01-01

Resolving the Ambiguities: An Industrial Hygiene (IAQ) Symposium was a one-day event designed to inform practicing industrial hygienists about highlight presentations made at Indoor Air `93. A broad range of topics was presented by invited speakers. Topics included were attempts to deal with guidelines and standards, questionnaires, odors and sensory irritation, respiratory allergies, neuroses, sick building syndrome (SBS), and multiple chemical sensitivity (MCS).

Hacking the hospital environment: young adults designing youth-friendly hospital rooms together with young people with cancer experiences.

PubMed

Boisen, Kirsten A; Boisen, Anne; Thomsen, Stine Legarth; Matthiesen, Simon Meggers; Hjerming, Maiken; Hertz, Pernille Grarup

2015-12-09

There is a need for youth-friendly hospital environments as the ward environment may affect both patient satisfaction and health outcomes. To involve young people in designing youth-friendly ward environment. We arranged a design competition lasting 42 h (Hackathon). Students in architecture, design, engineering, communication and anthropology participated (27 young adults) - forming eight groups. Adolescents and young adults (AYA) with current or former cancer experience participated as sparring partners. We provided workspace and food during the weekend. The groups presented their products to a jury and relevant stakeholders. The groups created eight unique design concepts. The young designers were extremely flexible listening to ideas and experiences from the young patients, which led to common features including individual and flexible design, privacy in two-bed wardrooms and social contact with other hospitalized AYA. The winning project included an integrated concept for both wardrooms and the AYA day room, including logos and names for the rooms and an 'energy wall' in the day room. A hackathon event was an effective mode of youth participation. The design concepts and ideas were in line with current evidence regarding pleasing hospital environment and youth-friendly inpatient facilities and may be applicable to other young patients.

NCI Think Tank Concerning the Identifiability of Biospecimens and “-Omic” Data

PubMed Central

Weil, Carol J.; Mechanic, Leah E.; Green, Tiffany; Kinsinger, Christopher; Lockhart, Nicole C.; Nelson, Stefanie A.; Rodriguez, Laura L.; Buccini, Laura D.

2014-01-01

On June 11 and 12, 2012, the National Cancer Institute (NCI) hosted a think tank concerning the identifiability of biospecimens and “omic” Data in order to explore challenges surrounding this complex and multifaceted topic. The think tank brought together forty-six leaders from several fields, including cancer genomics, bioinformatics, human subject protection, patient advocacy, and commercial genetics. The first day involved presentations regarding the state of the science of re-identification; current and proposed regulatory frameworks for assessing identifiability; developments in law, industry and biotechnology; and the expectations of patients and research participants. The second day was spent by think tank participants in small break-out groups designed to address specific sub-topics under the umbrella issue of identifiability, including considerations for the development of best practices for data sharing and consent, and targeted opportunities for further empirical research. We describe the outcomes of this two day meeting, including two complimentary themes that emerged from moderated discussions following the presentations on Day 1, and ideas presented for further empirical research to discern the preferences and concerns of research participants about data sharing and individual identifiability. PMID:23579437

Activities to Grow On: Friendship Links.

ERIC Educational Resources Information Center

Newman, Joan; And Others

1992-01-01

Presents a collection of Valentine's Day-related kindergarten activities designed to help friendships grow. They include making personalized place mats as a group, creating decorated mail pouches, building heart shaped bird feeders, reading a book about friendly secrets and surprises, and decorating hearts with compliments about each student. (SM)

When Home Was a Castle.

ERIC Educational Resources Information Center

Hennessey, Gail Skroback

1994-01-01

Presents middle school-level interdisciplinary activities for exploring medieval life. Students conduct research then create their own castles, design personal coats of arms, learn about jousting, go through a typical castle dweller's day, learn about carousels, discuss castle life from Mark Twain's perspective, and attend a medieval feast. (SM)

Aging in America: Fact, Fiction and Feeling.

ERIC Educational Resources Information Center

Strubbe, Mary A.

Thirteen lessons on aging in America, appropriate for the secondary school level, are presented. Each lesson is designed to take approximately one day and includes the goal, objectives, background information, reproducible student handouts, materials and equipment needed, procedures, and evaluation forms. In the first lesson students examine their…

Moloka'i: Fishponds.

ERIC Educational Resources Information Center

Hawaii State Dept. of Education, Honolulu. Office of Instructional Services.

Designed to help teachers implement marine education in their classrooms, this module provides information regarding a vanishing Hawaiian resource, fishponds. Due to the impact of present day human activities on shoreline areas, the size and number of fishponds have been greatly reduced; therefore, this module focuses on fishponds as a resource…

Endocarditis associated with cardiac catheterization due to a Gram-positive coccus designated Micrococcus mucilaginosus incertae sedis.

PubMed Central

Rubin, S J; Lyons, R W; Murcia, A J

1978-01-01

A gram-positive coccus, presently named Micrococcus mucilaginosus incertae sedis, was isolated from 14 blood cultures from a patient with endocarditis. The first positive blood culture was drawn 5 days after the patient underwent cardiac catheterization. PMID:670378

A two-stage aerobic/anaerobic denitrifying horizontal bioreactor designed for treating ammonium and H(2)S simultaneously.

PubMed

Chinalia, F A; Garbossa, L H P; Rodriguez, J A; Lapa, K R; Foresti, E

2012-11-01

A two-stage bioreactor was operated for a period of 140 days in order to develop a post-treatment process based on anaerobic bioxidation of sulfite. This process was designed for simultaneously treating the effluent and biogas of a full-scale UASB reactor, containing significant concentrations of NH(4) and H(2)S, respectively. The system comprised of two horizontal-flow bed-packed reactors operated with different oxygen concentrations. Ammonium present in the effluent was transformed into nitrates in the first aerobic stage. The second anaerobic stage combined the treatment of nitrates in the liquor with the hydrogen sulfide present in the UASB-reactor biogas. Nitrates were consumed with a significant production of sulfate, resulting in a nitrate removal rate of 0.43 kgNm(3)day(-1) and ≥92 % efficiency. Such a removal rate is comparable to those achieved by heterotrophic denitrifying systems. Polymeric forms of sulfur were not detected (elementary sulfur); sulfate was the main product of the sulfide-based denitrifying process. S-sulfate was produced at a rate of about 0.35 kgm(3)day(-1). Sulfur inputs as S-H(2)S were estimated at about 0.75 kgm(3)day(-1) and Chemical Oxygen Demand (COD) removal rates did not vary significantly during the process. DGGE profiling and 16S rRNA identified Halothiobacillus-like species as the key microorganism supporting this process; such a strain has not yet been previously associated with such bioengineered systems.

Effects on postoperative salivary cortisol of relaxation/music and patient teaching about pain management.

PubMed

Good, Marion; Albert, Jeffrey M; Arafah, Baha; Anderson, Gene Cranston; Wotman, Stephen; Cong, Xiaomei; Lane, Deforia; Ahn, Sukhee

2013-07-01

The physiological and psychological stress of surgery and postoperative pain can leave patients more susceptible to infection and complications. The present study was designed to determine whether two interventions, patient teaching (PT) for pain management and relaxation/music (RM), reduced cortisol levels, an indicator of stress, following abdominal surgery. Patients (18-75 years) were randomly assigned to receive PT, RM, a combination of the two, or usual care; the 205 patients with both pre- and posttest cortisol values were analyzed. A 2 × 2 factorial design was used to compare groups for PT effects and RM effects. Stress was measured by salivary cortisol before and after 20-min tests of the interventions in the morning and afternoon of postoperative Day 2. Saliva was stimulated with lemon juice and analyzed with high-sensitivity salivary cortisol enzyme immunoassay. Comparisons using analysis of covariance (ANCOVA), controlling for baseline levels, showed no PT effect or RM effect on cortisol in the morning or afternoon. Post hoc ANCOVA showed no significant effects when intervention groups were compared to the control group. Although in previous studies, RM reduced pain and music reduced cortisol on Day 1, in the present study the cortisol response to surgery was not attenuated by PT or RM on Day 2. The RM intervention can be used for pain but needs to be further tested for effects on plasma cortisol in abdominal surgery patients on their first postoperative day.

Microbial complexes levels in conventional and self-ligating brackets.

PubMed

Bergamo, Ana Zilda Nazar; Nelson-Filho, Paulo; Andrucioli, Marcela Cristina Damião; do Nascimento, Cássio; Pedrazzi, Vinícius; Matsumoto, Mírian Aiko Nakane

2017-05-01

The aims were to evaluate the levels of bacterial species in saliva and in situ and to assess whether the design of brackets influences the risk of developing periodontal disease. Twenty patients (13.3 mean age) were bonded with self-ligating brackets and a conventional bracket. Saliva was collected before bonding and 30 and 60 days after bonding. One sample of each bracket was removed 30 and 60 days after bonding. The analysis was determined by checkerboard DNA-DNA hybridization. The data was evaluated by the non-parametric test. A significant increase in the levels of bacterial species in the saliva occurred in 15 of the 22 analyzed species. The self-ligating brackets presented the highest incidence percentages for the orange and red complexes 60 days after bonding. In situ analyses showed different patterns according to the bracket design. The levels of Campylobacter rectus showed significant differences (p = 0.011) 60 days after bonding among the three brackets; the highest values were observed in the In-Ovation®R bracket. The bracket design seems to influence the levels of bacterial species involved in periodontal disease. Considering the wide variety of bacterial species, additional studies are needed to aid in the establishment of effective protocols to prevent the development of periodontal disease during orthodontic treatment. A dynamic alteration in the oral microbiota may lead to inflammatory reactions in the supporting soft and hard tissues. The different types of brackets interfere with bacterial adherence. Bracket design should be considered in orthodontic treatment.

Metals Recovery from Artificial Ore in Case of Printed Circuit Boards, Using Plasmatron Plasma Reactor

PubMed Central

Szałatkiewicz, Jakub

2016-01-01

This paper presents the investigation of metals production form artificial ore, which consists of printed circuit board (PCB) waste, processed in plasmatron plasma reactor. A test setup was designed and built that enabled research of plasma processing of PCB waste of more than 700 kg/day scale. The designed plasma process is presented and discussed. The process in tests consumed 2 kWh/kg of processed waste. Investigation of the process products is presented with their elemental analyses of metals and slag. The average recovery of metals in presented experiments is 76%. Metals recovered include: Ag, Au, Pd, Cu, Sn, Pb, and others. The chosen process parameters are presented: energy consumption, throughput, process temperatures, and air consumption. Presented technology allows processing of variable and hard-to-process printed circuit board waste that can reach up to 100% of the input mass. PMID:28773804

Metals Recovery from Artificial Ore in Case of Printed Circuit Boards, Using Plasmatron Plasma Reactor.

PubMed

Szałatkiewicz, Jakub

2016-08-10

This paper presents the investigation of metals production form artificial ore, which consists of printed circuit board (PCB) waste, processed in plasmatron plasma reactor. A test setup was designed and built that enabled research of plasma processing of PCB waste of more than 700 kg/day scale. The designed plasma process is presented and discussed. The process in tests consumed 2 kWh/kg of processed waste. Investigation of the process products is presented with their elemental analyses of metals and slag. The average recovery of metals in presented experiments is 76%. Metals recovered include: Ag, Au, Pd, Cu, Sn, Pb, and others. The chosen process parameters are presented: energy consumption, throughput, process temperatures, and air consumption. Presented technology allows processing of variable and hard-to-process printed circuit board waste that can reach up to 100% of the input mass.

Entry at Venus

NASA Technical Reports Server (NTRS)

Venkatapathy, Ethiraj; Smith, Brandon

2016-01-01

This is lecture to be given at the IPPW 2016, as part of the 2 day course on Short Course on Destination Venus: Science, Technology and Mission Architectures. The attached presentation material is intended to be introduction to entry aspects of Venus in-situ robotic missions. The presentation introduces the audience to the aerodynamic and aerothermodynamic aspects as well as the loads, both aero and thermal, generated during entry. The course touches upon the system design aspects such as TPS design and both high and low ballistic coefficient entry system concepts that allow the science payload to be protected from the extreme entry environment and yet meet the mission objectives.

Sexuality ... What's Spirituality Got to Do with It?

ERIC Educational Resources Information Center

DiGioia, Melissa Keyes

2011-01-01

Attitudes and beliefs about sexuality are informed by a variety of sources, including faith-based traditions. This lesson is designed for older adults to explore sexuality-related messages and values that are based on spiritual or faith perspectives. Participants will reflect upon their past learning, evaluate their present day attitudes about…

Traffic Flow Management: Data Mining Update

NASA Technical Reports Server (NTRS)

Grabbe, Shon R.

2012-01-01

This presentation provides an update on recent data mining efforts that have been designed to (1) identify like/similar days in the national airspace system, (2) cluster/aggregate national-level rerouting data and (3) apply machine learning techniques to predict when Ground Delay Programs are required at a weather-impacted airport

SEMINAR PUBLICATION: DESIGN, OPERATION, AND CLOSURE OF MUNICIPAL SOLID WASTE LANDFILLS

EPA Science Inventory

This report assists landfill owners and operators in complying with requirements under authority of subtitle D of the Resource Conservation and Recovery Act (RCRA) and Section 405 of the Clean Water Act. A series of 2-day seminars were presented in 14 different locations during t...

American Educational History: School, Society, and the Common Good

ERIC Educational Resources Information Center

Jeynes, William H.

2007-01-01

Designed for undergraduate and graduate courses in education, this book covers education developments and trends beginning with the Colonial experience through the present day, placing an emphasis on post-World War II issues such as the role of technology, the standards movement, affirmative action, bilingual education, undocumented immigrants,…

Getting to Know You...All about You: Preschool Orientation Manual.

ERIC Educational Resources Information Center

San Ysidro School District, CA.

Designed to guide teachers through a 20-day sequence of preschool orientation activities, the manual presents a numbered sequence of topics with related objectives and explanations, preparation and planning needs, and specific activities for children. Section I is entitled "All Around Us" and focuses on guiding preschool children and…

Poetry Workshop. Weave Poetry Through Your Day.

ERIC Educational Resources Information Center

Cullinan, Bee

1998-01-01

Presents a poetry across-the-curriculum activity designed to help primary school students build word-recognition skills and an appreciation for the natural world. Students read a poem about polliwogs aloud, discuss the sounds, examine spelling patterns, and investigate scientific details about polliwogs. The poem, "Polliwogs" is included. (SM)

Asian EFL University Students' Preference toward Teaching Approaches

ERIC Educational Resources Information Center

Mermelstein, Aaron David

2015-01-01

Designing and presenting lessons is the center of the teaching process. Every day teachers must make decisions about the instructional process. A teacher's approach can have an enormous impact on the effectiveness of his or her teaching. Understanding students' preferences toward teaching approaches and teaching styles can create opportunities for…

Understanding Writing--Process, Skill and Product. Dissemination Report.

ERIC Educational Resources Information Center

Ohio State Dept. of Education, Columbus.

This conference proceedings reflects the substance of the 3-day Conference on Written Communication, sponsored by the Ohio Department of Education and designed to provide professional growth opportunities for more than 350 school administrators, teachers, and university and state department personnel. The papers in the proceedings present a review…

Pump Operation Workshop. Third Edition (Revised).

ERIC Educational Resources Information Center

Ontario Ministry of the Environment, Toronto.

Presented is the learner's manual for a five-day workshop designed to supplement the skills of water and wastewater treatment personnel. The program consists of lecture-discussions and hands-on sessions covering the operation of water and wastewater pumps. Areas addressed include: material pumped, pump systems, types of pumps, pump controls,…

Beta-blocker withdrawal among patients presenting for surgery from home

PubMed Central

Schonberger, Robert B.; Lukens, Carrie L.; Turkoglu, O. Dicle; Feinleib, Jessica L.; Haspel, Kenneth L.; Burg, Matthew M.

2012-01-01

Structured Abstract Objective This study sought to measure the incidence of perioperative beta-blocker non-compliance by patients who were prescribed chronic beta blocker therapy and presented for surgery from home. The effect of patient non-compliance on day of surgery presenting heart rate was also examined. Design Prospective observational study with outcome data obtained from review of the medical record. Setting The preoperative clinic and operating rooms of a Veterans Administration hospital. Participants Patients on chronic beta blocker therapy who presented from home for surgery. Interventions None. Measurements and Main Results Demographic and comorbidity data as well as data on self-reported compliance to beta-blocker therapy, initial day of surgery vital signs, and recent ambulatory vital signs were collected. Ten out of fifty subjects (20%; 95% CI = 9-31%) reported not taking their day of surgery beta-blocker. These self-reported non-adherers demonstrated a higher presenting heart rate on the day of surgery vs. adherent subjects (median of 78 beats per minute vs. 65 beats per minute, p=0.02 by Wilcoxon Rank-Sum Test). The difference-in-difference between baseline primary care and day of surgery heart rate was also statistically significant between compliant and non-compliant subjects (-7 beats per minute vs. +12.5 beats per minute, p<0.00001). Conclusions Patient self-report and physiologic data documented failure to take beta-blockers and possible beta-blocker withdrawal in 20% of patients who presented for surgery from home. If these findings are confirmed in larger studies, improved patient understanding of and compliance with medication instructions during preoperative visits should be a focus of future quality improvement initiatives. PMID:22418043

Drawer compacted sand filter: a new and innovative method for on-site grey water treatment.

PubMed

Assayed, Almoayied; Chenoweth, Jonathan; Pedley, Steven

2014-01-01

In this paper, results ofa new sand filter design were presented. The drawer compacted sand filter (DCSF) is a modified design for a sand filter in which the sand layer is broken down into several layers, each of which is 10 cm high and placed in a movable drawer separated by a 10 cm space. A lab-scale DCSF was designed and operated for 330 days fed by synthetic grey water. The response of drawer sand filters to variable hydraulic and organic loading rates (HLR and OLR) in terms of biological oxygen demand (BODs), chemical oxygen demand (COD), total suspended solids (TSS), pH, electrical conductivity and Escherichia coli reductions were evaluated. The HLR was studied by increasing from 72 to 142 L m(-2) day(-1) and OLR was studied by increasing it from 23 to 30 g BOD5 m(-2) day(-1) while keeping the HLR constant at 142 L m(-2) day(-1). Each loading regime was applied for 110 days. Results showed that DCSF was able to remove >90% of organic matter and total suspended solids for all doses. No significant difference was noticed in terms of overall filter efficiency between different loads for all parameters. Significant reduction in BOD5 and COD (P < .05) was noticed after water was drained through the third drawer in all tested loads. The paper concludes that DCSF would be appropriate for use in dense urban areas as its footprint is small and is appropriate for a wide range of users because of its convenience and low maintenance requirements.

The Advanced Gamma-ray Imaging System (AGIS): Schwarzschild-Couder (SC) Telescope Mechanical and Optical System Design

NASA Astrophysics Data System (ADS)

Byrum, Karen L.; Vassiliev, V.; AGIS Collaboration

2010-03-01

AGIS is a concept for the next-generation ground-based gamma-ray observatory. It will be an array of 36 imaging atmospheric Cherenkov telescopes (IACTs) sensitive in the energy range from 50 GeV to 200 TeV. The required improvements in sensitivity, angular resolution, and reliability of operation relative to the present generation instruments imposes demanding technological and cost requirements on the design of AGIS telescopes. In this submission, we outline the status of the development of the optical and mechanical systems for a novel Schwarzschild-Couder two-mirror aplanatic telescope. This design can provide a field of view and angular resolution significantly better to those offered by the traditional Davies-Cotton optics utilized in present-day IACTs. Other benefits of the novel design include isochronous focusing and compatibility with cost-effective, high quantum efficiency image sensors such as multi-anode PMTs, silicon PMTs (SiPMs), or image intensifiers.

Acute withdrawal but not long-term withdrawal from methamphetamine affects sexual behavior in female rats.

PubMed

Thibodeau, Rachel B; Ornelas, Laura C; Romero, Jordan; Memos, Nicoletta; Scheible, Matthew; Avila, Alfred; Schumacher, Abby; Navarro, April; Zimmermann, Karen; Cuenod, Bethany A; Frohardt, Russell J; Guarraci, Fay A

2013-02-01

The present study was designed to investigate the long-term effects of repeated methamphetamine (MA) exposure on sexual motivation in female rats tested after a period of drug abstinence. In Experiment 1, female subjects received three injections of MA (1.0mg/kg/day, every other day) or saline and were tested for paced mating behavior (where females could control the receipt of sexual stimulation from one male rat) 21 days after their last injection. In Experiment 2, female subjects received 12 consecutive injections of MA (1.0mg/kg/day) or saline and were tested for mate choice (where females could control the receipt of sexual stimulation from two male rats simultaneously) 6 days after their last injection. Experiment 3 was identical to Experiment 2 except that female subjects received no baseline mating test and were tested for mate choice 24h and 6 days after their last injection. Open field tests were conducted in each experiment to measure locomotor activity after repeated exposure to MA. Although repeated MA exposure increased locomotor activity, mating behavior was not facilitated after either a short (6 days) or long (21 days) period of drug abstinence. Nevertheless, sexual behavior was disrupted during the 24h acute withdrawal period. Therefore, although the present study found no evidence of cross-sensitization between female sexual behavior and MA after either a short or a long period of drug abstinence, sexual behavior in sexually naïve female rats is sensitive to the depressive state associated with acute withdrawal from MA. In conclusion, the results of the present study suggest that MA acts differently from other psychomotor stimulants, and that the effects of MA withdrawal on sexual behavior differ between male and female rats. Copyright © 2012 Elsevier Inc. All rights reserved.

Task one report: Optical system study. [characteristics of laser equipment for space communication systems

NASA Technical Reports Server (NTRS)

1973-01-01

An optical system which can be incorporated in a present day or near future space-borne laser communications system is described. Techniques of implementing these systems are presented and their design problems and use are discussed. Optical system weight is estimated as a function of aperture diameter for a typical present day or near future laser communication system. The optical communications system considered is a two-way, high data rate optical communications link from a spacecraft to a spacecraft or from a spacecraft to a ground station. Each station has a laser transmitter and receiver and a pointing and tracking system. Thus each station can track the laser transmitter of the other. Optical beamwidths are considered to be as small as an arc-second with the beam pointed to a fraction of this beamwidth.

Poster Day Showcases Student Work | Poster

Cancer.gov

By Nathalie Walker, Guest Writer, and Carolynne Keenan, Contributing Writer On July 31, NCI at Frederick hosted Student Poster Day, an annual event in which student interns can showcase the work they do in their various positions in NCI at Frederick labs and offices. Participating students are interns in the Student Internship Program, a program designed for undergraduate and graduate students during their summer breaks, as well as interns in the Werner H. Kirsten Student Internship Program (WHK SIP), a program for high school seniors. All the students have an opportunity to present their scientific posters.

Acoustic Telemetry Evaluation of Juvenile Salmonid Passage and Survival at John Day Dam, 2011

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weiland, Mark A.; Woodley, Christa M.; Ploskey, Gene R.

This report presents survival, behavioral, and fish passage results for tagged yearling Chinook salmon and juvenile steelhead as part of a survival study conducted at John Day Dam during spring 2011. This study was designed to evaluate the passage and survival of yearling Chinook salmon and juvenile steelhead to assist managers in identifying dam operations for compliance testing as stipulated by the 2008 Federal Columbia River Power System Biological Opinion and the 2008 Columbia Basin Fish Accords. Survival estimates were based on a paired-release survival model.

Preclinical Explorative Assessment of Dimethyl Fumarate-Based Biocompatible Nanolipoidal Carriers for the Management of Multiple Sclerosis.

PubMed

Kumar, Pramod; Sharma, Gajanand; Gupta, Varun; Kaur, Ramanpreet; Thakur, Kanika; Malik, Ruchi; Kumar, Anil; Kaushal, Naveen; Raza, Kaisar

2018-05-16

Multiple sclerosis (MS) is a neurodegenerative disease in which myelin sheath damage occurs due to internal and external factors. MS especially affects the young population. Dimethyl fumarate (DMF) is a promising agent for MS treatment, although it is associated with concerns such as poor brain permeation, multiple dosing, and gastrointestinal flushing. The present study attempts to evaluate the preclinical performance of specially designed DMF-based lipoidal nanoparticles in a cuprizone-induced demyelination model in rodents. The studies proved the efficacy of lipid-based nanoparticles containing DMF in a once-a-day dosage regimen over that of thrice-a-day plain DMF administration on crucial parameters like motor coordination, grip strength, mortality, body weight, and locomotor activity. However, neither blank lipid nor blank neuroprotective (vitamins A, D, and E) loaded nanoparticles were able to elicit any desirable behavioral response. Histopathological studies showed that the designed once-a-day DMF nanomedicines were well tolerated and rejuvenated the myelin sheath vis-à-vis the plain DMF thrice-a-day regimen. These findings provide proof of concept for a biocompatible nanomedicine for MS with tremendous promise for effective brain delivery and patient compliance on the grounds of a reduction in the dosage frequency.

Preliminary Study on Kano Model in the Conceptual Design Activities for Product Lifecycle Improvement

NASA Astrophysics Data System (ADS)

Fahrul Hassan, Mohd; Rahman, M. R. A.; Arifin, A. M. T.; Ismail, A. E.; Rasidi Ibrahim, M.; Zulafif Rahim, M.; Fauzi Ahmad, Md

2017-08-01

Product manufactured with short life cycle had only one major issue, it can lead to increasing volume of waste. Day by day, this untreated waste had consumed many landfill spaces, waiting for any possible alternatives. Lack of product recovery knowledge and recyclability features imprinted into product design are one of the main reason behind all this. Sustainable awareness aspect should not just be implied into people’s mind, but also onto product design. This paper presents a preliminary study on Kano model method in the conceptual design activities to improve product lifecycle. Kano model is a survey-type method, used to analyze and distinguished product qualities or features, also how the customers may have perceived them. Three important attributes of Kano model are performance, attractive and must-be. The proposed approach enables better understanding of customer requirements while providing a way for Kano model to be integrated into engineering design to improve product’s end-of-life. Further works will be continued to provide a better lifecycle option (increase percentage of reuse, remanufacture or recycle, whereby decrease percentage of waste) of a product using Kano model approach.

ADP and brucellosis indemnity systems development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanders, W.M.; Harlan, B.L.

1976-01-01

Our initial study of the USDA/TAHC Brucellosis Indemnity Program in Texas has shown that both the efficiency and rate of claim payments can be increased by the application of present day computer technologies. Two main factors contribute to these increases: the number of discrepancies that are caused by poor penmanship, transposition of numbers, and other human errors can be monitored and minimized; and the documented information can be indexed, sorted, and searched faster, more efficiently, and without human error. The overall flow of documentation that is used to control the movement of infected or exposed animals through commerce should bemore » studied. A new system should be designed that fully utilizes present day computer and electronic technologies.« less

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Lijuan; Gonder, Jeff; Burton, Evan

This study evaluates the costs and benefits associated with the use of a plug-in hybrid electric bus and determines the cost effectiveness relative to a conventional bus and a hybrid electric bus. A sensitivity sweep analysis was performed over a number of a different battery sizes, charging powers, and charging stations. The net present value was calculated for each vehicle design and provided the basis for the design evaluation. In all cases, given present day economic assumptions, the conventional bus achieved the lowest net present value while the optimal plug-in hybrid electric bus scenario reached lower lifetime costs than themore » hybrid electric bus. The study also performed parameter sensitivity analysis under low market potential assumptions and high market potential assumptions. The net present value of plug-in hybrid electric bus is close to that of conventional bus.« less

Lunar South Pole Illumination: Review, Reassessment, and Power System Implications

NASA Technical Reports Server (NTRS)

Fincannon, James

2007-01-01

This paper reviews past analyses and research related to lunar south pole illumination and presents results of independent illumination analyses using an analytical tool and a radar digital elevation model. The analysis tool enables assessment at most locations near the lunar poles for any time and any year. Average illumination fraction, energy storage duration, solar/horizon terrain elevation profiles and illumination fraction profiles are presented for various highly illuminated sites which have been identified for manned or unmanned operations. The format of the data can be used by power system designers to develop mass optimized solar and energy storage systems. Data are presented for the worse case lunar day (a critical power planning bottleneck) as well as three lunar days during lunar south pole winter. The main site under consideration by present lunar mission planners (on the Crater Shackleton rim) is shown to have, for the worse case lunar day, a 0.71 average illumination fraction and 73 to 117 hours required for energy storage (depending on power system type). Linking other sites and including towers at either site are shown to not completely eliminate the need for energy storage.

Software-Based Visual Loan Calculator For Banking Industry

NASA Astrophysics Data System (ADS)

Isizoh, A. N.; Anazia, A. E.; Okide, S. O. 3; Onyeyili, T. I.; Okwaraoka, C. A. P.

2012-03-01

industry is very necessary in modern day banking system using many design techniques for security reasons. This paper thus presents the software-based design and implementation of a Visual Loan calculator for banking industry using Visual Basic .Net (VB.Net). The fundamental approach to this is to develop a Graphical User Interface (GUI) using VB.Net operating tools, and then developing a working program which calculates the interest of any loan obtained. The VB.Net programming was done, implemented and the software proved satisfactory.

Multicenter Trial of Rivaroxaban for Early Discharge of Pulmonary Embolism From the Emergency Department (MERCURY PE): Rationale and Design.

PubMed

Singer, Adam J; Xiang, Jim; Kabrhel, Christopher; Merli, Gino J; Pollack, Charles; Tapson, Victor F; Wildgoose, Peter; Peacock, W Frank

2016-11-01

Traditionally, patients with pulmonary embolism (PE) are admitted from the emergency department and treated with low-molecular-weight heparin followed by warfarin. Several studies now demonstrate that it is possible to identify low-risk PE patients that can safely be treated as outpatients. The advent of the direct-acting oral anticoagulants such as rivaroxaban has made it easier than ever to manage patients outside of the hospital. This article describes the design of a randomized controlled trial aimed at testing the hypothesis that low-risk PE patients can be safely and effectively managed at home using rivaroxaban, resulting in fewer days of hospitalization than standard-of-care treatment. We have initiated a multicenter, open-label, randomized clinical trial in which low-risk adult PE patients (identified by the Hestia criteria) are randomized to outpatient management with oral rivaroxaban 15 mg twice daily for 21 days followed by 20 mg once daily for 90 days versus standard care, determined by the treating physician and based on local practices. The primary clinical endpoint will be the total number of inpatient hospital days (including the index admission) for venous thromboembolic or bleeding-related events during the first 30 days after randomization. A total of 150 subjects per group will provide 82% power to detect a difference of 1 day or greater in the primary outcome. Patient enrollment is ongoing at present in 45 of 60 planned sites. No interim analysis is planned and the study is being monitored by a data safety management board. The MERCURY PE study is designed to test the hypothesis that outpatient management of low-risk PE patients with rivaroxaban reduces the number of hospitalization days from venous thromboembolism and bleeding compared with standard care. This article describes the rationale and methodology for this study. © 2016 by the Society for Academic Emergency Medicine.

High performance TWT development for the microwave power module

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whaley, D.R.; Armstrong, C.M.; Groshart, G.

1996-12-31

Northrop Grumman`s ongoing development of microwave power modules (MPM) provides microwave power at various power levels, frequencies, and bandwidths for a variety of applications. Present day requirements for the vacuum power booster traveling wave tubes of the microwave power module are becoming increasingly more demanding, necessitating the need for further enhancement of tube performance. The MPM development program at Northrop Grumman is designed specifically to meet this need by construction and test of a series of new tubes aimed at verifying computation and reaching high efficiency design goals. Tubes under test incorporate several different helix designs, as well as varyingmore » electron gun and magnetic confinement configurations. Current efforts also include further development of state-of-the-art TWT modeling and computational methods at Northrop Grumman incorporating new, more accurate models into existing design tools and developing new tools to be used in all aspects of traveling wave tube design. Current status of the Northrop Grumman MPM TWT development program will be presented.« less

A Practical HTS SQUID Magnetometer System for NDI of Aircraft

DTIC Science & Technology

1994-01-10

based on present-day high Tc SQUIDs is feasible, and present a portable design cooled by a miniature cryocooler . In addition, a reevaluation of the basic...integration of this cryocooler with SQUIDs, is that there is no available electromagnetic field emission information. We did not find any for other types ...background signals. Third, there are several other types of cryocoolers , integrated or split, made of plastics available on the market. They will

Behavioral effects of acclimatization to restraint protocol used for awake animal imaging.

PubMed

Reed, Michael D; Pira, Ashley S; Febo, Marcelo

2013-07-15

Functional MRI in awake rats involves acclimatization to restraint to minimize motion. We designed a study to examine the effects of an acclimatization protocol (5 days of restraint, 60 min per day) on the emission of 22-kHz ultrasonic vocalizations and performance in a forced swim test (FST). Our results showed that USV calls are reduced significantly by days 3, 4 and 5 of acclimatization. Although the rats showed less climbing activity (and more immobility) in FST on day 5 compared to the 1st day of restraint acclimatization, the difference was not detected once the animals were given a 2-week hiatus. Overall, we showed that animals adapt to the restraint over a five-day period; however, restraint may introduce confounding behavioral outcomes that may hinder the interpretation of results derived from awake rat imaging. The present data warrants further testing of the effects of MRI restraint on behavior. Copyright © 2013 Elsevier B.V. All rights reserved.

Risks to Students in School.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. Office of Technology Assessment.

Every day, school-aged children encounter a wide variety of hazards that occur both outside and inside schools. This document presents findings of a report that examined the scientific data on the risks for student injury and illness in the school environment. The information is designed to help administrators set priorities for reducing risks to…

Hamsters, Picture Books, and Engineering Design

ERIC Educational Resources Information Center

Tank, Kristina; Pettis, Christy; Moore, Tamara; Fehr, Abby

2013-01-01

With the integration of engineering into science instruction, teachers have been seeking ways to add engineering in their classrooms. This article presents a primary (K-2) STEM unit that took place in a half-day kindergarten classroom as a way to address the scientific and engineering practices (dimension 1, p.41) and the disciplinary core idea…

Solar Energy - Solution or Pipedream?

ERIC Educational Resources Information Center

Polk, Joyce

This series of lessons and class activities is designed for presentation in a sequence of nine class days. The collection is intended to provide the student in advanced science classes with awareness of the possibilities and limitations of solar energy as a potential solution to the energy crisis. Included are discussion of the following: (1)…

Lasers. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This document contains the materials required for presenting an 8-day competency-based technology learning activity (TLA) designed to introduce students in grades 6-10 to advances and career opportunities in the field of laser technology. The guide uses a series of hands-on exploratory experiences into which activities to help students develop…

Nutrition and Meal Planning in Child-Care Programs: A Practical Guide.

ERIC Educational Resources Information Center

Edelstein, Sari

Designed to assist child care center managers in planning nutritious meals for children in centers or licensed home day care programs, this guide presents information on the nutritional requirements of infants and children, sample menus for child care centers, and resources for further information. The first part of the guide details the…

Nonverbal Immediacy Behaviors and Online Student Engagement: Bringing Past Instructional Research into the Present Virtual Classroom

ERIC Educational Resources Information Center

Dixson, Marcia D.; Greenwell, Mackenzie R.; Rogers-Stacy, Christie; Weister, Tyson; Lauer, Sara

2017-01-01

Nonverbal immediacy behaviors are underresearched in the online teaching environment. Using social presence theory as a guiding framework, this study explores several online nonverbal immediacy behaviors: emoticons/figurative language, color, cohesion, visual imagery, and audio in course design; response latency, length, time of day, and message…

Building Community through Shared Spaces and Intention

ERIC Educational Resources Information Center

Hall, Maureen P.; Panarese, Christine M.

2016-01-01

Present-day educational approaches in higher education and K-12 privilege only cognitive gains from students, who are sometimes only seen as test scores, while neglecting the development of the whole human being. This article documents three unique Building Community events at a public university in the northeast, which were designed to embrace…

The Spiritual and Moral Education of Russia's School Students

ERIC Educational Resources Information Center

Daniliuk, A. Ia.; Kondakov, A. M.; Tishkov, V. A.

2010-01-01

This article discusses the new draft of the Federal State Standards of General Education which designates spiritual and moral upbringing as a key task of present-day education. In accordance with the Standards' requirements, the structure of the basic educational program shall, in addition to the fundamental nucleus of the content of the…

Some Vocabulary Activities Worth Teaching About.

ERIC Educational Resources Information Center

Brand, Helena S.

1982-01-01

The 12 activities presented in this pamphlet are intended to help make vocabulary study a stimulating experience for both teacher and student. The activities are as follows: (1) a commercially prepared list of suggestions for vocabulary development, (2) an exercise designed to relate vocabulary study to every day reading, (3) a variation of the…

Robotics-Control Technology. Technology Learning Activity. Teacher Edition. Technology Education Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This document contains the materials required for presenting an 8-day competency-based technology learning activity (TLA) designed to introduce students in grades 6-10 to advances and career opportunities in the field of robotics-control technology. The guide uses hands-on exploratory experiences into which activities to help students develop…

Solar Energy in the Home. Revised.

ERIC Educational Resources Information Center

Roeder, Allen A.; Woodland, James A.

Recommended for grades 10-12 physical, earth, or general science classes, this 5-7 day unit is designed to give students a general understanding of solar energy and its use as a viable alternative to present energy sources. Along with this technology, students examine several factors of solar energy which influence the choice of solar home site…

Muncie Remembers That Day of Infamy.

ERIC Educational Resources Information Center

Brant, Heather; And Others

This document presents an oral history project in which 34 residents of Munice, Indiana were interviewed about their experiences and memories of the Japanese attack on Pearl Harbor, December 7, 1941. The project was conducted by the members of an Honors United States History class at Munice Southside High School. The students designed the…

A Web-Based Contingency Management Program with Adolescent Smokers

ERIC Educational Resources Information Center

Reynolds, Brady; Dallery, Jesse; Shroff, Palak; Patak, Michele; Leraas, Kristen

2008-01-01

The present study evaluated a new 30-day Web-based contingency management program for smoking abstinence with 4 daily-smoking adolescents. Participants made 3 daily video recordings of themselves giving breath carbon monoxide (CO) samples at home that were sent electronically to study personnel. Using a reversal design, participants could earn…

Conference on Rural America Proceedings (Crookston, Minnesota, July 15, 16, 17, 1976).

ERIC Educational Resources Information Center

Whalen, Roz, Ed.

Presentations by nationally and internationally known speakers are in proceedings from the three-day conference. Rural futures; people, land, and water; and education and economics are major topics reported from the conference, which was designed to increase issue awareness among rural residents, increase dialogue among rural residents and between…

My Very Own Contract About the Energy Crisis.

ERIC Educational Resources Information Center

Williams, LaVora

This collection of lessons and class activities is designed for presentation during a sequence of five class days. The lessons are intended to emphasize the need for energy conservation by everyone. Seventh grade students will be taught methods for acquainting others of the nature of the energy situation and methods of making their homes more…

KENNEDY SPACE CENTER, FLA. - The overhead crane settles the Mars Exploration Rover 2 (MER-2) entry vehicle onto a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - The overhead crane settles the Mars Exploration Rover 2 (MER-2) entry vehicle onto a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

Re-assessing Present Day Global Mass Transport and Glacial Isostatic Adjustment From a Data Driven Approach

NASA Astrophysics Data System (ADS)

Wu, X.; Jiang, Y.; Simonsen, S.; van den Broeke, M. R.; Ligtenberg, S.; Kuipers Munneke, P.; van der Wal, W.; Vermeersen, B. L. A.

2017-12-01

Determining present-day mass transport (PDMT) is complicated by the fact that most observations contain signals from both present day ice melting and Glacial Isostatic Adjustment (GIA). Despite decades of progress in geodynamic modeling and new observations, significant uncertainties remain in both. The key to separate present-day ice mass change and signals from GIA is to include data of different physical characteristics. We designed an approach to separate PDMT and GIA signatures by estimating them simultaneously using globally distributed interdisciplinary data with distinct physical information and a dynamically constructed a priori GIA model. We conducted a high-resolution global reappraisal of present-day ice mass balance with focus on Earth's polar regions and its contribution to global sea-level rise using a combination of ICESat, GRACE gravity, surface geodetic velocity data, and an ocean bottom pressure model. Adding ice altimetry supplies critically needed dual data types over the interiors of ice covered regions to enhance separation of PDMT and GIA signatures, and achieve half an order of magnitude expected higher accuracies for GIA and consequently ice mass balance estimates. The global data based approach can adequately address issues of PDMT and GIA induced geocenter motion and long-wavelength signatures important for large areas such as Antarctica and global mean sea level. In conjunction with the dense altimetry data, we solved for PDMT coefficients up to degree and order 180 by using a higher-resolution GRACE data set, and a high-resolution a priori PDMT model that includes detailed geographic boundaries. The high-resolution approach solves the problem of multiple resolutions in various data types, greatly reduces aliased errors from a low-degree truncation, and at the same time, enhances separation of signatures from adjacent regions such as Greenland and Canadian Arctic territories.

Metals production

NASA Technical Reports Server (NTRS)

Beck, Theodore S.

1992-01-01

Existing procedures for design of electrochemical plants can be used for design of lunar processes taking into consideration the differences in environmental conditions. These differences include: 1/6 Earth gravity, high vacuum, solar electrical and heat source, space radiation heat sink, long days and nights, and different availability and economics of materials, energy, and labor. Techniques have already been developed for operation of relatively small scale hydrogen-oxygen fuel cell systems used in the U.S. lunar landing program. Design and operation of lunar aqueous electrolytic process plants appears to be within the state-of-the-art. Finding or developing compatible materials for construction and designing of fused-magma metal winning cells will present a real engineering challenge.

Vocal fold self-disruption after phonotrauma on a lead actor: a case presentation.

PubMed

Behlau, Mara; Oliveira, Gisele; Pontes, Paulo

2009-11-01

It is well known that phonotraumatic events may produce laryngeal inflammation, vocal fold hemorrhage and different types of mass lesions. This study describes a vocal fold self-disruption that occurred on stage to a lead actor in the role of Richard III. The study design is as case presentation. A 43-year-old actor presented with a sudden voice loss that first occurred on stage after a series of presentations. He also had a cold-like condition that had not been treated. His past medical history included an average of ten cigarettes per day for ten years and a 10-year history of gastritis and stomach ulcer. Perceptual, acoustic, and laryngeal analyses were performed following pharmacological and voice therapy. Perceptual and acoustic analyses showed mild deviations whereas laryngeal visual examination revealed a complete right vocal fold detachment from the anterior commissure to the vocal process, with generalized hyperemia. A mild diffuse Reinke's edema was observed on the left vocal fold. Mild discomfort was present only during the first day of the acute period. Modified vocal rest was recommended and a series of vocal exercises were administered. The patient performed again 4 days later, after following a series of behavioral modification techniques that included casting guidelines during the subsequent 15 days. Healing was exceptional and his voice returned to normal. This unique case with an exceptional recovery emphasizes the etiological aspects of scar formation after phonotrauma. Positive contributing factors may include a good vocal technique and adequate training as well as the protective upregulated genes present in Reinke's edema.

Sharp and the Jules Verne Launcher

NASA Astrophysics Data System (ADS)

Hunter, John; Cartland, Harry

1996-03-01

Lawrence Livermore National Laboratory (LLNL) has built the worlds largest hydrogen gas gun called SHARP, (Super High Altitude Research Project). Originally designed to launch 5 kg to a 450 km altitude, SHARP is configured horizontally at Site 300 in Tracy, California. SHARP is successfully delivering 5 kg scramjets at Mach 9 in aerophysics tests. Some of the results of the scramjet tests are enlightening and are presented insofar as they are relevant to future launches into space. Using a light gas gun to launch payloads into orbit has been analyzed. We look at LEO (Low Earth Orbit), GEO (Geosynchronous Earth Orbit), and LO (Lunar Orbit). We present a conceptual design for a large light gas gun called the Jules Verne Launcher (JVL). The JVL can deliver 3.3 metric tons to a 500 km low earth orbit. We anticipate one launch per day. We present the history of light gas guns, the SHARP design and performance, and the JVL design. Another section is devoted to the vehicle environment and resultant design. Lastly, we present a cost analysis. Our results indicated that the JVL will be able to deliver 1000 metric tons of payload to LEO yearly. The cost will be 5% of the best US rocket delivery cost. This technology will enable the next phase of man's exploration of space.

Power supplies for long duration balloon flights

NASA Astrophysics Data System (ADS)

Lichfield, Ernest W.

Long duration balloon flights require more electrical power than can be carried in primary batteries. This paper provides design information for selecting rechargeable batteries and charging systems. Solar panels for recharging batteries are discussed, with particular emphasis on cells mounting suitable for balloon flights and panel orientation for maximum power collection. Since efficient utilization of power is so important, modern DC to DC power conversion techniques are presented. On short flights of 1 day or less, system designers have not been greatly concerned with battery weight. But, with the advent of long duration balloon flights using superpressure balloons, anchor balloon systems, and RACOON balloon techniques, power supplies and their weight become of prime importance. The criteria for evaluating power systems for long duration balloon flights is performance per unit weight. Instrumented balloon systems have flown 44 days. For these very long duration flights, batteries recharged from solar cells are the only solution. For intermediate flight duration, say less than 10 days, the system designer should seriously consider using primary cells. The National Center for Atmospheric Research is sponsored by the National Science Foundation. Any opinions, findings and conclusions or recommendations expressed in this publication are those of the authors and do not necessarily reflect the views of the National Science Foundation.

Short-term prediction of solar energy in Saudi Arabia using automated-design fuzzy logic systems

PubMed Central

2017-01-01

Solar energy is considered as one of the main sources for renewable energy in the near future. However, solar energy and other renewable energy sources have a drawback related to the difficulty in predicting their availability in the near future. This problem affects optimal exploitation of solar energy, especially in connection with other resources. Therefore, reliable solar energy prediction models are essential to solar energy management and economics. This paper presents work aimed at designing reliable models to predict the global horizontal irradiance (GHI) for the next day in 8 stations in Saudi Arabia. The designed models are based on computational intelligence methods of automated-design fuzzy logic systems. The fuzzy logic systems are designed and optimized with two models using fuzzy c-means clustering (FCM) and simulated annealing (SA) algorithms. The first model uses FCM based on the subtractive clustering algorithm to automatically design the predictor fuzzy rules from data. The second model is using FCM followed by simulated annealing algorithm to enhance the prediction accuracy of the fuzzy logic system. The objective of the predictor is to accurately predict next-day global horizontal irradiance (GHI) using previous-day meteorological and solar radiation observations. The proposed models use observations of 10 variables of measured meteorological and solar radiation data to build the model. The experimentation and results of the prediction are detailed where the root mean square error of the prediction was approximately 88% for the second model tuned by simulated annealing compared to 79.75% accuracy using the first model. This results demonstrate a good modeling accuracy of the second model despite that the training and testing of the proposed models were carried out using spatially and temporally independent data. PMID:28806754

Short-term prediction of solar energy in Saudi Arabia using automated-design fuzzy logic systems.

PubMed

Almaraashi, Majid

2017-01-01

Solar energy is considered as one of the main sources for renewable energy in the near future. However, solar energy and other renewable energy sources have a drawback related to the difficulty in predicting their availability in the near future. This problem affects optimal exploitation of solar energy, especially in connection with other resources. Therefore, reliable solar energy prediction models are essential to solar energy management and economics. This paper presents work aimed at designing reliable models to predict the global horizontal irradiance (GHI) for the next day in 8 stations in Saudi Arabia. The designed models are based on computational intelligence methods of automated-design fuzzy logic systems. The fuzzy logic systems are designed and optimized with two models using fuzzy c-means clustering (FCM) and simulated annealing (SA) algorithms. The first model uses FCM based on the subtractive clustering algorithm to automatically design the predictor fuzzy rules from data. The second model is using FCM followed by simulated annealing algorithm to enhance the prediction accuracy of the fuzzy logic system. The objective of the predictor is to accurately predict next-day global horizontal irradiance (GHI) using previous-day meteorological and solar radiation observations. The proposed models use observations of 10 variables of measured meteorological and solar radiation data to build the model. The experimentation and results of the prediction are detailed where the root mean square error of the prediction was approximately 88% for the second model tuned by simulated annealing compared to 79.75% accuracy using the first model. This results demonstrate a good modeling accuracy of the second model despite that the training and testing of the proposed models were carried out using spatially and temporally independent data.

Design and Early In-flight Performance of the Tropical Rainfall Measuring Mission (TRMM) Power Subsystem

NASA Technical Reports Server (NTRS)

Moran, Vickie Eakin; Flatley, Thomas P.; Shue, John; Gaddy, Edward M.; Manzer, Dominic; Hicks, Edward

1998-01-01

Maryland built the spacecraft in-house with four U.S. instruments and one Japanese instrument, the first space flown Precipitation Radar (PR). The TRMM Observatory was successfully launched from Tanegashima Space Center in Japan on an H-2 Expendable Launch Vehicle on November 27, 1997. This paper presents an overview of the TRMM Power System including its design, testing, and in flight performance for the first 70 days. Finally, key lessons learned are presented. The TRMM power system consists of an 18.1 square meter deployed solar array fabricated by TRW with Tecstar GaAs/Ge cells, two (2) Hughes 50 Ampere-Hour (Ah) Super NiCd' batteries, each with 22 Eagle-Picher cells, and three (3) electronics boxes designed to provide power regulation, battery charge control, and command and telemetry interface.

Ultra-stable sub-meV monochromator for hard X-rays

DOE PAGES

Toellner, T. S.; Collins, J.; Goetze, K.; ...

2015-07-17

A high-resolution silicon monochromator suitable for 21.541 keV synchrotron radiation is presented that produces a bandwidth of 0.27 meV. The operating energy corresponds to a nuclear transition in 151Eu. The first-of-its-kind, fully cryogenic design achieves an energy-alignment stability of 0.017 meV r.m.s. per day, or a 100-fold improvement over other meV-monochromators, and can tolerate higher X-ray power loads than room-temperature designs of comparable resolution. This offers the potential for significantly more accurate measurements of lattice excitation energies using nuclear resonant vibrational spectroscopy if combined with accurate energy calibration using, for example, high-speed Doppler shifting. The design of the monochromator alongmore » with its performance and impact on transmitted beam properties are presented.« less

Trends of Serum Electrolyte Changes in Crush syndrome patients of Bam Earthquake; a Cross sectional Study.

PubMed

Safari, Saeed; Eshaghzade, Mehdi; Najafi, Iraj; Baratloo, Alireza; Hashemi, Behrooz; Forouzanfar, Mohammad Mehdi; Rahmati, Farhad

2017-01-01

Electrolyte imbalances are very common among crushed earthquake victims but there is not enough data regarding their trend of changes. The present study was designed to evaluate the trend of changes in sodium, calcium, and phosphorus ions among crush syndrome patients. In this retrospective cross-sectional study, using the database of Bam earthquake victims, which was developed by Iranian Society of Nephrology following Bam earthquake, Iran, 2003, the 10-day trend of sodium, calcium, and phosphorus ions changes in > 15 years old crush syndrome patients was evaluated. 118 patients with the mean age of 25.6 ± 6.9 years were studied (57.3 male). On the first day of admission, 52.5% (95% CI: 42.7 - 62.3) of the patients had hyponatremia, which reached 43.9% (95% CI: 28.5 - 59.3) on day 10. 100.0% of patients were hypocalcemic on admission and serum calcium level did not change dramatically during the 10 days of hospitalization. The prevalence of hyperphosphatemia on the first day was 90.5% (95% CI: 81.5 - 99.5) and on the 10 th day of hospitalization 66.7% (95% CI: 48.5 - 84.8) of the patients were still affected. The results of the present study shows the 52.5% prevalence of hyponatremia, 100% hypocalcemia, and 90.5% hyperphosphatemia among crush syndrome patients of Bam earthquake victims on the first day of admission. Evaluation of 10-day trend shows a slow decreasing pattern of these imbalances as after 10 days, 43.9% still remain hyponatremic, 92.3% hypocalcemic, and 66.7% hypophosphatemic.

[Interior] Configuration options, habitability and architectural aspects of the transfer habitat module (THM) and the surface habitat on Mars (SHM)/ESA's AURORA human mission to Mars (HMM) study

NASA Astrophysics Data System (ADS)

Imhof, Barbara

2007-02-01

This paper discusses the findings for [Interior] configuration options, habitability and architectural aspects of a first human spacecraft to Mars. In 2003 the space architecture office LIQUIFER was invited by the European Space Agency's (ESA) AURORA Program committee to consult the scientists and engineers from the European Space and Technology Center (ESTEC) and other European industrial communities with developing the first human mission to Mars, which will take place in 2030, regarding the architectural issues of crewed habitats. The task was to develop an interior configuration for a transfer vehicle (TV) to Mars, especially a transfer habitation module (THM) and a surface habitat module (SHM) on Mars. The total travel time Earth—Mars and back for a crew of six amounts to approximately 900 days. After a 200-day-flight three crewmembers will land on Mars in the Mars excursion vehicle (MEV) and will live and work in the SHM for 30 days. For 500 days before the 200-day journey back the spacecraft continues to circle the Martian orbit for further exploration. The entire mission program is based on our present knowledge of technology. The project was compiled during a constant feedback-design process and trans-disciplinary collaboration sessions in the ESA-ESTEC concurrent design facility. Long-term human space flight sets new spatial conditions and requirements to the design concept. The guidelines were developed from relevant numbers and facts of recognized standards, interviews with astronauts/cosmonauts and from analyses about habitability, sociology, psychology and configuration concepts of earlier space stations in combination with the topics of the individual's perception and relation of space. Result of this study is the development of a prototype concept for the THM and SHM with detailed information and complete plans of the interior configuration, including mass calculations. In addition the study contains a detailed explanation of the development of the Design process including all suggested design and configuration options.

MiTEP's Collaborative Field Course Design Process Based on Earth Science Literacy Principles

NASA Astrophysics Data System (ADS)

Engelmann, C. A.; Rose, W. I.; Huntoon, J. E.; Klawiter, M. F.; Hungwe, K.

2010-12-01

Michigan Technological University has developed a collaborative process for designing summer field courses for teachers as part of their National Science Foundation funded Math Science Partnership program, called the Michigan Teacher Excellence Program (MiTEP). This design process was implemented and then piloted during two two-week courses: Earth Science Institute I (ESI I) and Earth Science Institute II (ESI II). Participants consisted of a small group of Michigan urban science teachers who are members of the MiTEP program. The Earth Science Literacy Principles (ESLP) served as the framework for course design in conjunction with input from participating MiTEP teachers as well as research done on common teacher and student misconceptions in Earth Science. Research on the Earth Science misconception component, aligned to the ESLP, is more fully addressed in GSA Abstracts with Programs Vol. 42, No. 5. “Recognizing Earth Science Misconceptions and Reconstructing Knowledge through Conceptual-Change-Teaching”. The ESLP were released to the public in January 2009 by the Earth Science Literacy Organizing Committee and can be found at http://www.earthscienceliteracy.org/index.html. Each day of the first nine days of both Institutes was focused on one of the nine ESLP Big Ideas; the tenth day emphasized integration of concepts across all of the ESLP Big Ideas. Throughout each day, Michigan Tech graduate student facilitators and professors from Michigan Tech and Grand Valley State University consistantly focused teaching and learning on the day's Big Idea. Many Earth Science experts from Michigan Tech and Grand Valley State University joined the MiTEP teachers in the field or on campus, giving presentations on the latest research in their area that was related to that Big Idea. Field sites were chosen for their unique geological features as well as for the “sense of place” each site provided. Preliminary research findings indicate that this collaborative design process piloted as ESI I and ESI II was successful in improving MiTEP teacher understanding of Earth Science content and that it was helpful to use the ESLP framework. Ultimately, a small sample of student scores will look at the impact on student learning in the MiTEP teacher classrooms.

Using environmental engineering to increase hand hygiene compliance: a cross-over study protocol

PubMed Central

Schmidtke, Kelly Ann; Aujla, Navneet; Marshall, Tom; Hussain, Abid; Hodgkinson, Gerard P; Arheart, Kristopher; Marti, Joachim; Birnbach, David J; Vlaev, Ivo

2017-01-01

Introduction Compliance with hand hygiene recommendations in hospital is typically less than 50%. Such low compliance inevitably contributes to hospital-acquired infections that negatively affect patients’ well-being and hospitals’ finances. The design of the present study is predicated on the assumption that most people who fail to clean their hands are not doing so intentionally, they just forget. The present study will test whether psychological priming can be used to increase the number of people who clean their hands on entering a ward. Here, we present the protocol for this study. Methods and analysis The study will use a randomised cross-over design. During the study, each of four wards will be observed during four conditions: olfactory prime, visual prime, both primes and neither prime. Each condition will be experienced for 42 days followed by a 7-day washout period (total duration of trial=189 days). We will record the number of people who enter each ward and whether they clean their hands during observation sessions, the amount of cleaning material used from the dispensers each week and the number of hospital-acquired infections that occur in each period. The outcomes will be compared using a regression analysis. Following the initial trail, the most effective priming condition will be rolled out for 3 months in all the wards. Ethics and dissemination Research ethics approval was obtained from the South Central—Oxford C Research Ethics Committee (16/SC/0554), the Health Regulatory Authority and the sponsor. Trial registration number ISRCTN (15397624); Edge ID 86357. PMID:28893752

Design of visible and IR infrared dual-band common-path telescope system

NASA Astrophysics Data System (ADS)

Guo, YuLin; Yu, Xun; Tao, Yu; Jiang, Xu

2018-01-01

The use of visible and IR infrared dual-band combination can effectively improve the performance of photoelectric detection system,TV and IR system were designed with the common path by the common reflection optical system.A TV/IR infrared common-caliber and common-path system is designed,which can realize the Remote and all-day information.For the 640×512 cooled focal plane array,an infrared middle wave system was presented with a focal length of 600mm F number of 4 field of view(FOV) of 0.38°×0.43°, the system uses optical passive thermal design, has o compact structure and can meet 100% cold shield efficiency,meanwhile it meets the design requirements of lightweight and athermalization. For the 1920×1080 pixels CCD,a visible (TV) system ,which had 500mm focal length, 4F number,was completed.The final optical design along with their modulation transfer function is presented,showing excellent imaging performance in dual-band at the temperature range between -40° and 60°.

Evaluation of Cerebral Oxygenation in Neonates with Sepsis with Near-Infrared Spectroscopy.

PubMed

Rallis, Dimitrios; Karagianni, Paraskevi; Milona, Eleni; Pratsiou, Paraskevi; Nikolaidis, Nikolaos; Tsakalidis, Christos

2017-04-01

Objective  Neonates with sepsis have increased risk of cerebral injury. Our aim was to evaluate cerebral oxygenation in septic neonates using near-infrared spectroscopy. Study Design  A prospective study was designed enrolling neonates with sepsis, as defined by the International Consensus Conference of Pediatric Sepsis criteria and matched controls. Three cerebral half-hourly measurements were performed during the first, third, and seventh day of the episode and the values of tissue oxygenation index (TOI) and fractional tissue oxygen extraction (FTOE) were compared between the two groups. Result  The study population consisted of 50 septic and 44 control neonates with similar characteristics. No differences on TOI and FTOE were recorded in the first and third day. However, on the seventh day, septic neonates had significantly decreased oxygenation (62.7 ± 7 vs. 71.4 ± 4.4%, p  < 0.001) and increased oxygen extraction (0.35 ± 0.07 vs. 0.27 ± 0.05, p  < 0.001), irrespectively of the severity of the infection. Conclusion  Although septic neonates have normal cerebral oxygenation in the first and third day of the sepsis, they present decreased cerebral oxygenation in the seventh day independently of the infection severity. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Metric integration architecture for product development

NASA Astrophysics Data System (ADS)

Sieger, David B.

1997-06-01

Present-day product development endeavors utilize the concurrent engineering philosophy as a logical means for incorporating a variety of viewpoints into the design of products. Since this approach provides no explicit procedural provisions, it is necessary to establish at least a mental coupling with a known design process model. The central feature of all such models is the management and transformation of information. While these models assist in structuring the design process, characterizing the basic flow of operations that are involved, they provide no guidance facilities. The significance of this feature, and the role it plays in the time required to develop products, is increasing in importance due to the inherent process dynamics, system/component complexities, and competitive forces. The methodology presented in this paper involves the use of a hierarchical system structure, discrete event system specification (DEVS), and multidimensional state variable based metrics. This approach is unique in its capability to quantify designer's actions throughout product development, provide recommendations about subsequent activity selection, and coordinate distributed activities of designers and/or design teams across all design stages. Conceptual design tool implementation results are used to demonstrate the utility of this technique in improving the incremental decision making process.

Raza de Tesoros. Programa de Lectura y Ensenanza del Lenguaje, Unidad B. Guia para el Maestro (Race of Treasures. Reading and Language Learning Program, Unit B. Teacher's Guide).

ERIC Educational Resources Information Center

Dissemination and Assessment Center for Bilingual Education, Austin, TX.

This is the teacher's guide accompanying a reader and a workbook that are part of an ungraded language arts and reading program that can be used in classes from upper elementary through high school. The program is designed around reading selections which present aspects of history, culture, and present-day experiences of special relevance to the…

Jet aircraft emissions during cruise: Present and future

NASA Technical Reports Server (NTRS)

Grobman, J. S.

1975-01-01

Forecasts of engine exhaust emissions that may be practicably achievable for future commercial aircraft operating at high altitude cruise conditions are compared to cruise emission for present day aircraft. The forecasts are based on: (1) knowledge of emission characteristics of combustors and augmentors; (2) combustion research in emission reduction technology, and (3) trends in projected engine designs for advanced subsonic or supersonic commercial aircraft. Recent progress that was made in the evolution of emissions reduction technology is discussed.

Geostationary Coastal Ecosystem Dynamics Imager (GEO CEDI) for the GEO Coastal and Air Pollution Events (GEO CAPE) Mission. Concept Presentation

NASA Technical Reports Server (NTRS)

Janz, Scott; Smith, James C.; Mannino, Antonio

2010-01-01

This slide presentation reviews the concepts of the Geostationary Coastal Ecosystem Dynamics Imager (GEO CEDI) which will be used on the GEO Coastal and Air Pollution Events (GEO CAPE) Mission. The primary science requirements require scans of the U.S. Coastal waters 3 times per day during the daylight hours. Included in the overview are presentations about the systems, the optics, the detectors, the mechanical systems, the electromechanical systems, the electrical design, the flight software, the thermal systems, and the contamination prevention requirements.

Rollerblading in children: the Edinburgh experience.

PubMed Central

McGrath, D; Beattie, T F

1996-01-01

OBJECTIVE: To determine the incidence and severity of injuries sustained by children who present to an accident and emergency (A&E) department following rollerblading accidents. DESIGN: A prospective case-control study. SETTING: The A&E department of a city centre paediatric teaching hospital. METHODS: Data were collected on a specially designed proforma on each child presenting with an injury sustained while rollerblading. The injury severity score was calculated for each patient and details were taken of the length of admission or outpatient follow up where appropriate. RESULTS: Seventy four children (37 male; 37 female) presented with injuries over a three month period. The age range was 6-13 years in both groups. Half the injuries occurred at weekends. Fractures (n = 37) and soft tissue injuries (n = 28) were the most prevalent; 89% of injuries involved the limbs. Sixty eight children (92%) required treatment in A&E. Four (3%) were admitted to hospital and required operative procedures under general anaesthetic. The injury severity score ranged from 1 to 9 with a mean of 2.8. The length of hospital stay for admissions was 1-3 days; 47 children required follow up in the outpatient department (1-3 visits). Average length of outpatient contact was 18 days. CONCLUSIONS: This study shows a greater incidence of rollerblading injuries than has been reported elsewhere. No figures are at present available for the United Kingdom as a whole. PMID:8894866

Trajectory design for the Deep Space Program Science Experiment (DSPSE) mission

NASA Astrophysics Data System (ADS)

Carrington, D.; Carrico, J.; Jen, J.; Roberts, C.; Seacord, A.; Sharer, P.; Newman, L.; Richon, K.; Kaufman, B.; Middour, J.

In 1994, the Deep Space Program Science Experiment (DSPSE) spacecraft will become the first spacecraft to perform, in succession, both a lunar orbiting mission and a deep-space asteroid encounter mission. The primary mission objective is to perform a long-duration flight-test of various new-technology lightweight components, such as sensors, in a deep-space environment. The mission has two secondary science objectives: to provide high-resolution imaging of the entire lunar surface for mapping purposes and flyby imaging of the asteroid 1620 Geographos. The DSPSE mission is sponsored by the Strategic Defense Initiative Organization (SDIO). As prime contractor, the Naval Research Laboratory (NRL) is building the spacecraft and will conduct mission operations. The Goddard Space Flight Center's (GSFC) Flight Dynamics Division is supporting NRL in the areas of The Deep Space Network (DSN) will provide tracking support. The DSPSE mission will begin with a launch from the Western Test Range in late January 1994. Following a minimum 1.5-day stay in a low-Earth parking orbit, a solid kick motor burn will boost DSPSE into an 18-day, 2.5-revolution phasing orbit transfer trajectory to the Moon. Two burns to insert DSPSE into a lunar polar orbit suitable for the mapping mission will be followed by mapping orbit maintenance and adjustment operations over a period of 2 sidereal months. In May 1994, a lunar orbit departure maneuver, in conjunction with a lunar swingby 26 days later, will propel DSPSE onto a heliocentric transfer that will intercept Geographos on September 1, 1994. This paper presents the characteristics, deterministic delta-Vs, and design details of each trajectory phase of this unique mission, together with the requirements, constraints, and design considerations to which each phase is subject. Numerous trajectory plots and tables of significant trajectory events are included. Following a discussion of the results of a preliminary launch window analysis, a summary of the deterministic impulsive delta-V budget required to establish the baseline mission trajectory design is presented.

Development of a Ne gas target for {sup 22}Na production by proton irradiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mandal, Bidhan Ch., E-mail: mechbidhan@gmail.com; Pal, Gautam; Barua, Luna

2016-03-15

The article presents the design and development of a neon gas target for the production of {sup 22}Na using a proton beam from the room temperature cyclotron in Variable Energy Cyclotron Centre, Kolkata. The target design is made to handle a beam power of 85 W (17 MeV, 5 μA). The design is based on simulation using the computer code FLUKA for the beam dump and CFD-CFX for target cooling. The target has been successfully used for the production of {sup 22}Na in a 6 day long 17 MeV, 5 μA proton irradiation run.

Proposal for a low cost close air support aircraft for the year 2000: The Raptor

NASA Technical Reports Server (NTRS)

Brown, Jerome D.; Dewitt, Ward S.; Mcdonald, Mark; Riley, John W.; Roberts, Anthony E.; Watson, Sean; Whelan, Margaret M.

1991-01-01

The Raptor is a proposed low cost Close Air Support (CAS) aircraft for the U.S. Military. The Raptor incorporates a 'cranked arrow' wing planform, and uses canards instead of a traditional horizontal tail. The Raptor is designed to be capable of responsive delivery of effective ordnance in close proximity to friendly ground forces during the day, night, and 'under the weather' conditions. Details are presented of the Raptor's mission, configuration, performance, stability and control, ground support, manufacturing, and overall cost to permit engineering evaluation of the proposed design. A description of the design process and analysis methods used is also provided.

Recent advances in medicinal chemistry of sulfonamides. Rational design as anti-tumoral, anti-bacterial and anti-inflammatory agents.

PubMed

Shah, Syed Shoaib Ahmad; Rivera, Gildardo; Ashfaq, Muhammad

2013-01-01

Now-a-days, cancer is becoming one of the major problems of public health in the world. Pharmacology treatment is a way to increase quality and long life. Predominantly, in last decade sulfonamide derivatives have been described as potential carbonic anhydrase inhibitors. In the present work, we describe recent advances during the last decade in medicinal chemistry of sulfonamides derivatives with some examples of rational design as anti-tumoral, antibacterial and anti-inflammatory agents. We show strategy design, structure-activity relationship, biological activity and advances of new sulfonamide compounds that have more health significance than some clinically used sulfonamides.

Development of a preprototype vapor compression distillation water recovery subsystem

NASA Technical Reports Server (NTRS)

Johnson, K. L.

1978-01-01

The activities involved in the design, development, and test of a preprototype vapor compression distillation water recovery subsystem are described. This subsystem, part of a larger regenerative life support evaluation system, is designed to recover usable water from urine, urinal rinse water, and concentrated shower and laundry brine collected from three space vehicle crewmen for a period of 180 days without resupply. Details of preliminary design and testing as well as component developments are included. Trade studies, considerations leading to concept selections, problems encountered, and test data are also presented. The rework of existing hardware, subsystem development including computer programs, assembly verification, and comprehensive baseline test results are discussed.

An evaluation of study design for estimating a time-of-day noise weighting

NASA Technical Reports Server (NTRS)

Fields, J. M.

1986-01-01

The relative importance of daytime and nighttime noise of the same noise level is represented by a time-of-day weight in noise annoyance models. The high correlations between daytime and nighttime noise were regarded as a major reason that previous social surveys of noise annoyance could not accurately estimate the value of the time-of-day weight. Study designs which would reduce the correlation between daytime and nighttime noise are described. It is concluded that designs based on short term variations in nighttime noise levels would not be able to provide valid measures of response to nighttime noise. The accuracy of the estimate of the time-of-day weight is predicted for designs which are based on long term variations in nighttime noise levels. For these designs it is predicted that it is not possible to form satisfactorily precise estimates of the time-of-day weighting.

Water and waste water reclamation in a 21st century space colony

NASA Technical Reports Server (NTRS)

Jebens, H. J.; Johnson, R. D.

1977-01-01

The paper presents the results of research on closed-life support systems initiated during a system design study on space colonization and concentrates on the water and waste water components. Metabolic requirements for the 10,000 inhabitants were supplied by an assumed earth-like diet from an intensive agriculture system. Condensed atmospheric moisture provided a source of potable water and a portion of the irrigation water. Waste water was reclaimed by wet oxidation. The dual-water supply required the condensation of 175 kg/person-day of atmospheric water and the processing of 250 kg/person-day of waste water.

Acoustic Telemetry Evaluation of Juvenile Salmonid Passage and Survival at John Day Dam, 2010

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weiland, Mark A.; Woodley, Christa M.; Ploskey, Gene R.

This report presents survival, behavioral, and fish passage results for yearling and subyearling Chinook salmon smolts and juvenile steelhead tagged with JSATS acoustic micro-transmitters as part of a survival study conducted at John Day Dam during 2010. This study was designed to evaluate the passage and survival of yearling and subyearling Chinook salmon and juvenile steelhead to assist managers in identifying dam operations for compliance testing as stipulated by the 2008 Federal Columbia River Power System Biological Opinion and the 2008 Columbia Basin Fish Accords. Survival estimates were based on a single-release survival estimate model.

Local positioning with sensor-enabled passive multistandard RFID transponders

NASA Astrophysics Data System (ADS)

Heidrich, J.; Brenk, D.; Essel, J.; Schwarzer, S.; Herschmann, R.; Geck, B.; Fischer, G.; Weigel, R.

2010-11-01

RFID is used today in many fields of every day life like access control, anti-theft protection or logistics. Within this article a short overview of the basic RFID principles and the EPC protocol flow is given at first. Afterwards new design approaches for RFID systems within the scope of the research project RFID-S are presented.

Being Black in America, K-12. A Multimedia Listing of the 70's.

ERIC Educational Resources Information Center

Dean, Frances C., Comp.

This catalog lists over 600 sources, including books, records, kits, and filmstrips covering both black American and African history, folklore, literature, and present day life. It is designed to assist personnel in the selection of media for schools. The contents are organized according to the Dewey Decimal Classification System: Generalities;…

Knowledge Enriched Learning by Converging Knowledge Object & Learning Object

ERIC Educational Resources Information Center

Sabitha, Sai; Mehrotra, Deepti; Bansal, Abhay

2015-01-01

The most important dimension of learning is the content, and a Learning Management System (LMS) suffices this to a certain extent. The present day LMS are designed to primarily address issues like ease of use, search, content and performance. Many surveys had been conducted to identify the essential features required for the improvement of LMS,…

Succeeding in the Secondary Classroom: Strategies for Middle and High School Teachers.

ERIC Educational Resources Information Center

Arnold, Harriett

This book presents ideas for beginning secondary teachers who want to excel during their first year of teaching. The eight chapters focus on: (1) "Before the First Days of School" (e.g., classroom design, school policies, important people to know, dressing for success, special education students, school records, and emergency procedures); (2) "The…

Digital Avionics Information System (DAIS): Impact of DAIS Concept on Life Cycle Cost. Final Report.

ERIC Educational Resources Information Center

Goclowski, John C.; And Others

Designed to identify and quantify the potential impacts of the Digital Avionics Information System (DAIS) on weapon system personnel requirements and life cycle cost (LCC), this study postulated a typical close-air-support (CAS) mission avionics suite to serve as a basis for comparing present day and DAIS configuration specifications. The purpose…

SUGGESTED ACTIVITIES FOR NON-ENGLISH SPEAKING BEGINNERS, THE FIRST WEEK.

ERIC Educational Resources Information Center

Education Service Center Region 1, Edinburg, TX.

THIS PLAN, COVERING THE FIRST FIVE DAYS OF A BILINGUAL FIRST GRADE CLASS, WAS DESIGNED TO AID BEGINNING TEACHERS OF NON-ENGLISH SPEAKING CHILDREN MEET SOME OF THE SITUATIONS THEY WILL ENCOUNTER. (SPECIAL EMPHASIS IS ON SPANISH-SPEAKING CHILDREN.) THE DAILY SCHEDULE IS PRESENTED AS A GUIDE TO BE ADJUSTED ACCORDING TO NEED. IN ADDITION TO THE…

An Intercultural Seminar for Foreign and U.S. University Students.

ERIC Educational Resources Information Center

Colorado State Univ., Ft. Collins.

Presented is a discussion of an intercultural orientation seminar for foreign and U.S. university students at Colorado State University. This 1-day retreat is held each semester at a lodge in the Rocky Mountains. It is designed to bring together the students and community people to experience an international environment where the goal is to…

Reusing Old Manufacturing Buildings

ERIC Educational Resources Information Center

Roman, Harry T.

2014-01-01

This article presents an interesting design challenge for students, one that will certainly let them integrate subject matter and get a sense of pride for doing something useful in their own community. The author would be willing to bet that the average town or city has some old red brick manufacturing building(s) that have seen much better days.…

Disclosure Day on Relativity: A Science Activity beyond the Classroom

ERIC Educational Resources Information Center

Aragoneses, Andres; Salan, M. Nuria; Hernandez-Fernandez, Antonio

2017-01-01

An important goal for students in engineering education is the ability to present and defend a project in front of a technical audience. We have designed an activity for helping students to work the independent learning and communication skills, while they are introduced in the dynamics of a conference. In this activity, students prepare and…

The Epic Narrative of Intellectual Culture as a Framework for Curricular Coherence.

ERIC Educational Resources Information Center

Carson, Robert N.

2002-01-01

Describes a proposed middle school curriculum designed to coordinate the major subject areas around a single coherent story line and tell the epic tale of the development of formal intellectual culture from its distant origins to the present day. Ourstory explores the history of scientific culture from the perspective of foundational disciplines…

Safety and Health for Industrial/Vocational Education; for Supervisors and Instructors.

ERIC Educational Resources Information Center

Firenze, Robert J.; Walters, James B.

This course is designed to enable industrial/vocational education supervisors and instructors to establish and administer effective safety and health programs in their schools. Although the course is intended as complete training to be given over a 3-day period, it may be divided into individual units for presentation over longer periods of time.…

South Africa/Time Running Out.

ERIC Educational Resources Information Center

Clark, Todd, Ed.

1984-01-01

Based on the book, "South Africa: Time Running Out," a report of the Study Commission on U.S. Policy Toward Southern Africa, this 10-20 day unit of study is designed to help high school students learn about the history, geography, and present situation in South Africa and its relationship to the United States. The first of four sections…

Patterns of Maternal Behavior--Revisited.

ERIC Educational Resources Information Center

Holden, George W.; Ritchie, Kathy L.

This study was designed to look for patterns of parental behavior by assessing styles of child rearing in a novel way--through responses on an interactive computer program simulating an average day in the life of a mother and a preschooler. Presented to each subject (39 mothers of preschoolers and a control group of non-mothers) were 30 common…

Survey of World Art: Instructional Guide and Resource.

ERIC Educational Resources Information Center

Montgomery County Public Schools, Rockville, MD.

The guide is designed to help high school art teachers develop an introductory art survey course which focuses on the basic elements and theoretical principles of art products from prehistory through the present day. A major objective of the course is to help students analyze the relationships between art and society and between the artist and…

A Formative Evaluation of Healthy Habits, Healthy U: A Collaborative School-Based Cancer Education Program

ERIC Educational Resources Information Center

Anderson, Alicia; Spear, Caile; Pritchard, Mary; George, Kayla; Young, Kyle; Smith, Carrie

2017-01-01

Purpose: Healthy Habits, Healthy U (HHHU) is a two-day school-based primary prevention cancer education program that uses interactive classroom presentations designed to help students learn how to reduce their cancer risks. HHHU is a collaboration between a local cancer hospital, school district and university. HHHU incorporates real cancerous and…

Struggle and Success: The State of Teacher Education at Tribal Colleges and Universities

ERIC Educational Resources Information Center

Lamb, Carmelita

2016-01-01

From the earliest partnerships between Tribal Colleges and Universities (TCUs) and state colleges and universities, to the present-day independent bachelor's and master's degree teacher education programs, there has been a change in how higher education is designed to meet the uniquely Indigenous way that knowledge is exchanged, leading to greater…

Small craft identification discrimination criteria N 50 and V 50 for visible and infrared sensors in maritime security

NASA Astrophysics Data System (ADS)

Krapels, Keith; Deaver, Dawne; Driggers, Ronald

2006-09-01

The new emphasis on Anti-Terrorism and Force Protection (AT/FP), for both shore and sea platform protection, has resulted in a need for infrared imager design and evaluation tools which demonstrate field performance against U.S. Navy AT/FP requirements. In the design of infrared imaging systems for target acquisition, a discrimination criterion is required for successful sensor realization. It characterizes the difficulty of the task being performed by the observer and varies for different target sets. This criterion is used in both assessment of existing infrared sensor and in the design of new conceptual sensors. In this experiment, we collected 12 small craft signatures (military and civilian) in the visible band during the day and the LWIR and MWIR spectra in both the day and the night environments. These signatures were processed to determine the targets' characteristic dimension and contrast. They were also processed to bandlimit the signature's spatial information content (simulating longer range) and a perception experiment was performed to determine the task difficulty (N 50 and V 50). The results are presented in this paper and can be used for Navy and Coast Guard imaging infrared sensor design and evaluation.

Midwave infrared and visible sensor performance modeling: small craft identification discrimination criteria for maritime security

NASA Astrophysics Data System (ADS)

Krapels, Keith; Driggers, Ronald G.; Deaver, Dawne; Moker, Steven K.; Palmer, John

2007-10-01

The new emphasis on Anti-Terrorism and Force Protection (AT/FP), for both shore and sea platform protection, has resulted in a need for infrared imager design and evaluation tools that demonstrate field performance against U.S. Navy AT/FP requirements. In the design of infrared imaging systems for target acquisition, a discrimination criterion is required for successful sensor realization. It characterizes the difficulty of the task being performed by the observer and varies for different target sets. This criterion is used in both assessment of existing infrared sensor and in the design of new conceptual sensors. We collected 12 small craft signatures (military and civilian) in the visible band during the day and the long-wave and midwave infrared spectra in both the day and the night environments. These signatures were processed to determine the targets' characteristic dimension and contrast. They were also processed to band limit the signature's spatial information content (simulating longer range), and a perception experiment was performed to determine the task difficulty (N50 and V50). The results are presented and can be used for Navy and Coast Guard imaging infrared sensor design and evaluation.

Radon detection system, design, test and performance

NASA Astrophysics Data System (ADS)

Balcázar, M.; Chávez, A.; Piña-Villalpando, G.; Navarrete, M.

1999-02-01

A portable radon detection system (α-Inin) has been designed and constructed for using it in adverse environmental conditions where humidity, temperature and chemical vaporous are present. The minimum integration time is in periods of 15 min during 41 days. A 12 V battery and a photovoltaic module allow the α-Inin autonomy in field measurements. Data is collected by means of a laptop computer where data processing and α-Inin programming are carried out. α-Inin performance was simultaneously tested in a controlled radon chamber, together with a commercial α-Meter.

Aerospace Power Systems Design and Analysis (APSDA) Tool

NASA Technical Reports Server (NTRS)

Truong, Long V.

1998-01-01

The conceptual design of space and/or planetary electrical power systems has required considerable effort. Traditionally, in the early stages of the design cycle (conceptual design), the researchers have had to thoroughly study and analyze tradeoffs between system components, hardware architectures, and operating parameters (such as frequencies) to optimize system mass, efficiency, reliability, and cost. This process could take anywhere from several months to several years (as for the former Space Station Freedom), depending on the scale of the system. Although there are many sophisticated commercial software design tools for personal computers (PC's), none of them can support or provide total system design. To meet this need, researchers at the NASA Lewis Research Center cooperated with Professor George Kusic from the University of Pittsburgh to develop a new tool to help project managers and design engineers choose the best system parameters as quickly as possible in the early design stages (in days instead of months). It is called the Aerospace Power Systems Design and Analysis (APSDA) Tool. By using this tool, users can obtain desirable system design and operating parameters such as system weight, electrical distribution efficiency, bus power, and electrical load schedule. With APSDA, a large-scale specific power system was designed in a matter of days. It is an excellent tool to help designers make tradeoffs between system components, hardware architectures, and operation parameters in the early stages of the design cycle. user interface. It operates on any PC running the MS-DOS (Microsoft Corp.) operating system, version 5.0 or later. A color monitor (EGA or VGA) and two-button mouse are required. The APSDA tool was presented at the 30th Intersociety Energy Conversion Engineering Conference (IECEC) and is being beta tested at several NASA centers. Beta test packages are available for evaluation by contacting the author.

Design of smart home sensor visualizations for older adults.

PubMed

Le, Thai; Reeder, Blaine; Chung, Jane; Thompson, Hilaire; Demiris, George

2014-01-01

Smart home sensor systems provide a valuable opportunity to continuously and unobtrusively monitor older adult wellness. However, the density of sensor data can be challenging to visualize, especially for an older adult consumer with distinct user needs. We describe the design of sensor visualizations informed by interviews with older adults. The goal of the visualizations is to present sensor activity data to an older adult consumer audience that supports both longitudinal detection of trends and on-demand display of activity details for any chosen day. The design process is grounded through participatory design with older adult interviews during a six-month pilot sensor study. Through a secondary analysis of interviews, we identified the visualization needs of older adults. We incorporated these needs with cognitive perceptual visualization guidelines and the emotional design principles of Norman to develop sensor visualizations. We present a design of sensor visualization that integrate both temporal and spatial components of information. The visualization supports longitudinal detection of trends while allowing the viewer to view activity within a specific date. Appropriately designed visualizations for older adults not only provide insight into health and wellness, but also are a valuable resource to promote engagement within care.

Design of smart home sensor visualizations for older adults.

PubMed

Le, Thai; Reeder, Blaine; Chung, Jane; Thompson, Hilaire; Demiris, George

2014-07-24

Smart home sensor systems provide a valuable opportunity to continuously and unobtrusively monitor older adult wellness. However, the density of sensor data can be challenging to visualize, especially for an older adult consumer with distinct user needs. We describe the design of sensor visualizations informed by interviews with older adults. The goal of the visualizations is to present sensor activity data to an older adult consumer audience that supports both longitudinal detection of trends and on-demand display of activity details for any chosen day. The design process is grounded through participatory design with older adult interviews during a six-month pilot sensor study. Through a secondary analysis of interviews, we identified the visualization needs of older adults. We incorporated these needs with cognitive perceptual visualization guidelines and the emotional design principles of Norman to develop sensor visualizations. We present a design of sensor visualization that integrate both temporal and spatial components of information. The visualization supports longitudinal detection of trends while allowing the viewer to view activity within a specific date.CONCLUSIONS: Appropriately designed visualizations for older adults not only provide insight into health and wellness, but also are a valuable resource to promote engagement within care.

Orion Versus Poseidon: Understanding How Nasa's Crewed Capsule Survives Nature's Fury

NASA Technical Reports Server (NTRS)

Barbre, Robert E., Jr.

2016-01-01

This presentation summarizes the Marshall Space Flight Center Natural Environments Terrestrial and Planetary Environments (TPE) Team support to the NASA Orion space vehicle. The Orion vehicle, part of the Multi-Purpose Crew Vehicle Program, is designed to carry astronauts beyond low-Earth orbit and is currently undergoing a series of tests including Exploration Flight Test (EFT)-1. This design must address the natural environment to which the capsule and launch vehicle are exposed during all mission phases. In addition, the design must, to the best extent possible, implement the same process and data to be utilized on launch day. The TPE utilizes meteorological data to assess the sensitivities of the vehicle due to the terrestrial environment. The presentation describes examples of TPE support for vehicle design and several tests, as well as support for EFT-1 and planning for upcoming Exploration Missions while emphasizing the importance of accounting for the natural environment's impact to the vehicle early in the vehicle's program.

Design of a rectal probe for diffuse optical spectroscopy imaging for chemotherapy and radiotherapy monitoring

NASA Astrophysics Data System (ADS)

van de Giessen, Martijn; Santoro, Ylenia; Mirzaei Zarandi, Soroush; Pigazzi, Alessio; Cerussi, Albert E.; Tromberg, Bruce J.

2014-03-01

Diffuse optical spectroscopy imaging (DOSI) has shown great potential for the early detection of non-responding tumors during neoadjuvant chemotherapy in breast cancer, already one day after therapy starts. Patients with rectal cancer receive similar chemotherapy treatment. The rectum geometry and tissue properties of healthy and tumor tissue in the rectum and the requirement of surface contact impose constraints on the probe design. In this work we present the design of a DOSI probe with the aim of early chemotherapy/radiotherapy effectiveness detection in rectal tumors. We show using Monte Carlo simulations and phantom measurements that the colon tissue can be characterized reliably using a source-detector separation in the order of 10 mm. We present a design and rapid prototype of a probe for DOSI measurements that can be mounted on a standard laparoscope and that fits through a standard rectoscope. Using predominantly clinically approved components we aim at fast clinical translation.

Analytical methods in the high conversion reactor core design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zeggel, W.; Oldekop, W.; Axmann, J.K.

High conversion reactor (HCR) design methods have been used at the Technical University of Braunschweig (TUBS) with the technological support of Kraftwerk Union (KWU). The present state and objectives of this cooperation between KWU and TUBS in the field of HCRs have been described using existing design models and current activities aimed at further development and validation of the codes. The hard physical and thermal-hydraulic boundary conditions of pressurized water reactor (PWR) cores with a high degree of fuel utilization result from the tight packing of the HCR fuel rods and the high fissionable plutonium content of the fuel. Inmore » terms of design, the problem will be solved with rod bundles whose fuel rods are adjusted by helical spacers to the proposed small rod pitches. These HCR properties require novel computational models for neutron physics, thermal hydraulics, and fuel rod design. By means of a survey of the codes, the analytical procedure for present-day HCR core design is presented. The design programs are currently under intensive development, as design tools with a solid, scientific foundation and with essential parameters that are widely valid and are required for a promising optimization of the HCR core. Design results and a survey of future HCR development are given. In this connection, the reoptimization of the PWR core in the direction of an HCR is considered a fascinating scientific task, with respect to both economic and safety aspects.« less

NASA-LaRc Flight-Critical Digital Systems Technology Workshop

NASA Technical Reports Server (NTRS)

Meissner, C. W., Jr. (Editor); Dunham, J. R. (Editor); Crim, G. (Editor)

1989-01-01

The outcome is documented of a Flight-Critical Digital Systems Technology Workshop held at NASA-Langley December 13 to 15 1988. The purpose of the workshop was to elicit the aerospace industry's view of the issues which must be addressed for the practical realization of flight-critical digital systems. The workshop was divided into three parts: an overview session; three half-day meetings of seven working groups addressing aeronautical and space requirements, system design for validation, failure modes, system modeling, reliable software, and flight test; and a half-day summary of the research issues presented by the working group chairmen. Issues that generated the most consensus across the workshop were: (1) the lack of effective design and validation methods with support tools to enable engineering of highly-integrated, flight-critical digital systems, and (2) the lack of high quality laboratory and field data on system failures especially due to electromagnetic environment (EME).

Nuclear Forensics for High School Science

NASA Astrophysics Data System (ADS)

Mader, Catherine; Doss, Heide; Plisch, Monica; Isola, Drew; Mirakovitz, Kathy

2011-04-01

We developed an education module on nuclear forensics, designed for high school science classrooms. The lessons include a mix of hands-on activities, computer simulations, and written exercises. Students are presented with realistic scenarios designed to develop their knowledge of nuclear science and its application to nuclear forensics. A two-day teacher workshop offered at Hope College attracted 20 teachers. They were loaned kits to implement activities with their students, and each teacher spent 3--7 days on the lessons. All who reported back said they would do it again and would share the lessons with colleagues. Many said that access to equipment and ready-made lessons enabled them to expand what they taught about nuclear science and introduce nuclear forensics. A few teachers invited guest speakers to their classroom, which provided an excellent opportunity to share career information with students. We acknowledge generous support from the Department of Homeland Security and the AIP Meggars Award.

Ameliorative effect of chromium-d-phenylalanine complex on indomethacin-induced inflammatory bowel disease in rats.

PubMed

Nagarjun, S; Dhadde, Shivsharan B; Veerapur, Veeresh P; Thippeswamy, B S; Chandakavathe, Baburao N

2017-05-01

Present study was designed to evaluate the effect of chromium-d-phenylalanine complex (Cr (d-phe) 3 ) on indomethacin-induced inflammatory bowel disease (IBD) in rats. Adult Wistar rats were pretreated with vehicle/Cr (d-phe) 3 (30, 60 and 90μg/kg, p.o.) for 11days. On day 8 and 9, after one h of the above mentioned treatment, indomethacin (7.5mg/kg/day,s.c.) was administered to induce IBD. On day 12, blood samples were collected from animals for lactate dehydrogenase (LDH) estimation and ileum was isolated for macroscopic scoring, biochemical estimation (lipid peroxidation, reduced glutathione and myeloperoxidase activity) and histopathological study. Administration of indomethacin significantly altered the serum LDH, macroscopic and microscopic appearance and biochemical parameters in ileum tissue. Cr (d-phe) 3 , at all the tested doses, caused a significant reversal of changes induced by indomethacin. Present study demonstrates the protective effect of Cr (d-phe) 3 against indomethacin-induced IBD in rats. The observed protective effect might be attributed to the antioxidant and anti-inflammatory properties of Cr (d-phe) 3 . Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Spatial distributions of heating, cooling, and industrial degree-days in Turkey

NASA Astrophysics Data System (ADS)

Yildiz, I.; Sosaoglu, B.

2007-11-01

The degree-day method is commonly used to estimate energy consumption for heating and cooling in residential, commercial and industrial buildings, as well as in greenhouses, livestock facilities, storage facilities and warehouses. This article presents monthly and yearly averages and spatial distributions of heating, cooling, and industrial degree-days at the base temperatures of 18 °C and 20 °C, 18 °C and 24 °C, and 7 °C and 13 °C, respectively; as well as the corresponding number of days in Turkey. The findings presented here will facilitate the estimation of heating and cooling energy consumption for any residential, commercial and industrial buildings in Turkey, for any period of time (monthly, seasonal, etc.). From this analysis it will also be possible to compare and design alternative building systems in terms of energy efficiencies. If one prefers to use set point temperatures to indicate the resumption of the heating season would also be possible using the provided information in this article. In addition, utility companies and manufacturing/marketing companies of HVAC systems would be able to easily determine the demand, marketing strategies and policies based on the findings in this study.

KSC-2012-4257

NASA Image and Video Library

2012-08-03

CAPE CANAVERAL, Fla. -- Caley Burke, NASA Flight Design and Flight Controls engineer, speaks to about 45 of NASA’s social media followers for two days of presentations on the Kennedy Space Center's past, present and future. The social media participants gathered at the Florida spaceport on Aug. 2 and 3, 2012 to hear from key former and current leaders who related stories of the space agency's efforts to explore the unknown. It was the first social media event totally run by Kennedy. Photo credit: NASA/ Gianni Woods

1st Joint European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC 2015)

PubMed Central

Le Borgne, Marc; Haidar, Samer; Duval, Olivier; Wünsch, Bernhard; Jose, Joachim

2015-01-01

The European Conference on Therapeutic Targets and Medicinal Chemistry is a new two-day meeting on drug discovery that is focused on therapeutic targets and the use of tools to explore all fields of drug discovery and drug design such as molecular modelling, bioorganic chemistry, NMR studies, fragment screening, in vitro assays, in vivo assays, structure activity relationships, autodisplay. Abstracts of keynote lectures, plenary lectures, junior lectures, flash presentations, and posters presented during the meeting are collected in this report. PMID:26712767

Prevalence, diagnosis, and disease course of pertussis in adults with acute cough: a prospective, observational study in primary care

PubMed Central

Teepe, Jolien; Broekhuizen, Berna DL; Ieven, Margareta; Loens, Katherine; Huygen, Kris; Kretzschmar, Mirjam; de Melker, Hester; Butler, Chris C; Little, Paul; Stuart, Beth; Coenen, Samuel; Goossens, Herman; Verheij, Theo JM

2015-01-01

Background Most cases of adult pertussis probably remain undiagnosed. Aim To explore the prevalence, diagnosis, and disease course of acute pertussis infection in adult patients presenting with acute cough. Design and setting Prospective observational study between 2007 and 2010 in primary care in 12 European countries. Method Adults presenting with acute cough (duration of ≤28 days) were included. Bordetella pertussis infection was determined by polymerase chain reaction (from nasopharyngeal flocked swabs and sputa) and by measurement of immunoglobulin G antibodies to pertussis toxin (PT) in venous blood at day 28. An antibody titre to PT of ≥125 IU/ml or PCR positive result in a respiratory sample defined recent infection. Patients completed a symptom diary for 28 days. Results Serum and/or respiratory samples were obtained in 3074 patients. Three per cent (93/3074) had recent B. pertussis infection. Prior cough duration >2 weeks discriminated to some extent between those with and without pertussis (adjusted odds ratio 1.89, 95% confidence interval = 1.17 to 3.07; P = 0.010). Median cough duration after presentation was 17 and 12 days in patients with and without pertussis, respectively (P = 0.008). Patients with pertussis had longer duration of phlegm production (P = 0.010), shortness of breath (P = 0.037), disturbed sleep (P = 0.013) and interference with normal activities or work (P = 0.033) after presentation. Conclusion Pertussis infection plays a limited role among adults presenting with acute cough in primary care, but GPs should acknowledge the possibility of pertussis in uncomplicated lower respiratory tract infection. As in children, pertussis also causes prolonged symptoms in adults. However, pertussis is difficult to discern from other acute cough syndromes in adults at first presentation. PMID:26412843

Daily Mean Temperature Affects Urolithiasis Presentation in Seoul: a Time-series Analysis.

PubMed

Lee, SeoYeon; Kim, Min-Su; Kim, Jung Hoon; Kwon, Jong Kyou; Chi, Byung Hoon; Kim, Jin Wook; Chang, In Ho

2016-05-01

This study aimed to investigate the overall cumulative exposure-response and the lag response relationships between daily temperature and urolithiasis presentation in Seoul. Using a time-series design and distributing lag nonlinear methods, we estimated the relative risk (RR) of urolithiasis presentation associated with mean daily temperature, including the cumulative RR for a 20 days period, and RR for individual daily lag through 20 days. We analyzed data from 14,518 patients of 4 hospitals emergency department who sought medical evaluation or treatment of urolithiasis from 2005-2013 in Seoul. RR was estimated according to sex and age. Associations between mean daily temperature and urolithiasis presentation were not monotonic. Furthermore, there was variation in the exposure-response curve shapes and the strength of association at different temperatures, although in most cases RRs increased for temperatures above the 13°C reference value. The RRs for urolothiasis at 29°C vs. 13°C were 2.54 in all patients (95% confidence interval [CI]: 1.67-3.87), 2.59 in male (95% CI, 1.56-4.32), 2.42 in female (95% CI, 1.15-5.07), 3.83 in male less than 40 years old (95% CI, 1.78-8.26), and 2.47 in male between 40 and 60 years old (95% CI, 1.15-5.34). Consistent trends of increasing RR of urolithiasis presentation were observed within 5 days of high temperatures across all groups. Urolithiasis presentation increased with high temperature with higher daily mean temperatures, with the strongest associations estimated for lags of only a few days, in Seoul, a metropolitan city in Korea.

Concerns about covert HIV testing are associated with delayed presentation of suspected malaria in Ethiopian children: a cross-sectional study

PubMed Central

2014-01-01

Background Early diagnosis is important in preventing mortality from malaria. The hypothesis that guardians’ fear of covert human immunodeficiency virus (HIV) testing delays presentation of children with suspected malaria was tested. Methods The study design is a cross-sectional survey. The study population consisted of guardians of children with suspected malaria who presented to health centres in Oromia Region, Ethiopia. Data were collected on attitudes to HIV testing and the duration of children’s symptoms using interview administered questionnaires. Results Some 830 individuals provided data representing a response rate of 99% of eligible participants. Of these, 423 (51%) guardians perceived that HIV testing was routinely done on blood donated for malaria diagnosis, and 353 (43%) were aware of community members who delayed seeking medical advice because of these concerns. Children whose guardians suspected that blood was covertly tested for HIV had longer median delay to presentation for evaluation at health centres compared to those children whose guardians did not hold this belief (three days compared to two days, p < 0.001). Children whose guardians were concerned about covert HIV testing were at a higher odds of a prolonged delay before being seen at a health centre (odds ratio 1.73, 95% confidence intervals: 1.10 to 270 for a delay of ≥3 days compared to those seen in ≤2 days). Conclusion Children whose guardians believed that covert testing for HIV was routine clinical practice presented later for investigation of suspected malaria. This may account for up to 14% of the delay in presentation and represents a reversible risk factor for suboptimal management of malaria. PMID:25098338

Energy consciousness in the design of lighting for people

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halldane, J.F.

1975-01-01

A comprehensive overview of energy and power distribution in the environment is presented as it relates to lighting. The objectives are to develop a consciousness of the effects of light and vision in order to utilize them more effectively. Notes are made of the physical effects of radiant power on living things and materials including thermal absorption, reflection, transmission, refraction, spectral conversion, interference, diffraction, polarization, phototropy, luminescence, photochemical changes, and photoelectric effects. Environmental issues are stressed. The evaluation process in design is briefly discussed. Reference is made to the goal, parameter, synthesis, and criterion specification as a checklist for evaluation.more » Particular concern is raised for the occupants who experience the constructed environment, since their interests do not appear to be sufficiently represented in the present day design process. Meaningfulness of measurement is emphasized and some anomalies illustrated. (auth)« less

Photodetectors for the Advanced Gamma-ray Imaging System (AGIS)

NASA Astrophysics Data System (ADS)

Wagner, Robert G.; Advanced Gamma-ray Imaging System AGIS Collaboration

2010-03-01

The Advanced Gamma-Ray Imaging System (AGIS) is a concept for the next generation very high energy gamma-ray observatory. Design goals include an order of magnitude better sensitivity, better angular resolution, and a lower energy threshold than existing Cherenkov telescopes. Each telescope is equipped with a camera that detects and records the Cherenkov-light flashes from air showers. The camera is comprised of a pixelated focal plane of blue sensitive and fast (nanosecond) photon detectors that detect the photon signal and convert it into an electrical one. Given the scale of AGIS, the camera must be reliable and cost effective. The Schwarzschild-Couder optical design yields a smaller plate scale than present-day Cherenkov telescopes, enabling the use of more compact, multi-pixel devices, including multianode photomultipliers or Geiger avalanche photodiodes. We present the conceptual design of the focal plane for the camera and results from testing candidate! focal plane sensors.

William Paley's lost "intelligent design".

PubMed

Shapiro, Adam R

2009-01-01

William Paley's Natural Theology has experienced a resurgence in popularity in recent decades with the continuing controversies over the teaching of evolution and the emergence of a new "intelligent design" movement. But while both the movement's supporters and detractors agree that Paley is an intellectual forefather of the present-day movement, this agreement is forged at the expense of historical accuracy. Paley's intelligent design has almost nothing in common with the present day movement and, in fact, suggests theological arguments against the type of reasoning used by the modern movement. Paley wrote in reaction to Hume and in response to the evolutionary theories of Buffon and Erasmus Darwin. In this light, the Natural Theology suggests a different reading than it is usually given. Paley's narrowly-argued theology relies upon the ability to detect the presence of "purpose" in nature without relying upon knowing what those purposes are. His empirically-argued theology leads him to a God who operates through natural law, not in its contravention, and his concern goes far beyond proving the existence of a deity to undertaking the theological project of determining the attributes and characteristics of the deity. Though not himself an evolutionist, Paley put forth a theological worldview consistent with evolution. In fact, given his arguments that the observation of great contrivance increases the testimony of nature to God's power, Paley's philosophy might be more consistent with a theistic Darwinian evolution than with special creation.

Brain Ultrasonography Findings in Neonatal Seizure; a Cross-sectional Study.

PubMed

Nabavi, Seyed Saeed; Partovi, Parinaz

2017-01-01

Screening of newborns with seizure, who have curable pathologic brain findings, might be able to improve their final outcome by accelerating treatment intervention. The present study aimed to evaluate the brain ultrasonography findings of newborns hospitalized with complaint of seizure. The present cross-sectional study designed to evaluate brain ultrasonography findings of hospitalized newborns complaining seizure. Neonatal seizure was defined as presence of tonic, clonic, myoclonic, and subtle attacks in 1 - 28 day old newborns. 100 newborns with the mean age of 5.82 ± 6.29 days were evaluated (58% male). Most newborns were in the < 10 days age range (76%), term (83%) and with normal birth weight (81%). 22 (22%) of the ultrasonography examinations showed a pathologic finding. A correlation was only found between birth age and probability of the presence of a pathologic problem in the brain as the frequency of these problems was significantly higher in pre-term newborns (p = 0.023). Based on the findings of the present study, frequency of pathologic findings in neonatal brain ultrasonography was 22%. Hemorrhage (12%) and hydrocephaly (7%) were the most common findings. The only factor correlating with increased probability of positive findings was the newborns being pre-term.

Present and projected future mean radiant temperature for three European cities

NASA Astrophysics Data System (ADS)

Thorsson, Sofia; Rayner, David; Lindberg, Fredrik; Monteiro, Ana; Katzschner, Lutz; Lau, Kevin Ka-Lun; Campe, Sabrina; Katzschner, Antje; Konarska, Janina; Onomura, Shiho; Velho, Sara; Holmer, Björn

2017-09-01

Present-day and projected future changes in mean radiant temperature, T mrt in one northern, one mid-, and one southern European city (represented by Gothenburg, Frankfurt, and Porto), are presented, and the concept of hot spots is adopted. Air temperature, T a , increased in all cities by 2100, but changes in solar radiation due to changes in cloudiness counterbalanced or exacerbated the effects on T mrt. The number of days with high T mrt in Gothenburg was relatively unchanged at the end of the century (+1 day), whereas it more than doubled in Frankfurt and tripled in Porto. The use of street trees to reduce daytime radiant heat load was analyzed using hot spots to identify where trees could be most beneficial. Hot spots, although varying in intensity and frequency, were generally confined to near sunlit southeast-southwest facing walls, in northeast corner of courtyards, and in open spaces in all three cities. By adding trees in these spaces, the radiant heat load can be reduced, especially in spaces with no or few trees. A set of design principles for reducing the radiant heat load is outlined based on these findings and existing literature.

Design and implementation of fast bipolar clock drivers for CCD imaging systems in space applications

NASA Astrophysics Data System (ADS)

Jayarajan, Jayesh; Kumar, Nishant; Verma, Amarnath; Thaker, Ramkrishna

2016-05-01

Drive electronics for generating fast, bipolar clocks, which can drive capacitive loads of the order of 5-10nF are indispensable for present day Charge Coupled Devices (CCDs). Design of these high speed bipolar clocks is challenging because of the capacitive loads that have to be driven and a strict constraint on the rise and fall times. Designing drive electronics circuits for space applications becomes even more challenging due to limited number of available discrete devices, which can survive in the harsh radiation prone space environment. This paper presents the design, simulations and test results of a set of such high speed, bipolar clock drivers. The design has been tested under a thermal cycle of -15 deg C to +55 deg C under vacuum conditions and has been designed using radiation hardened components. The test results show that the design meets the stringent rise/fall time requirements of 50+/-10ns for Multiple Vertical CCD (VCCD) clocks and 20+/-5ns for Horizontal CCD (HCCD) clocks with sufficient design margins across full temperature range, with a pixel readout rate of 6.6MHz. The full design has been realized in flexi-rigid PCB with package volume of 140x160x50 mm3.

Combination of an electrolytic pretreatment unit with secondary water reclamation processes

NASA Technical Reports Server (NTRS)

Wells, G. W.; Bonura, M. S.

1973-01-01

The design and fabrication of a flight concept prototype electrolytic pretreatment unit (EPU) and of a contractor-furnished air evaporation unit (AEU) are described. The integrated EPU and AEU potable water recovery system is referred to as the Electrovap and is capable of processing the urine and flush water of a six-man crew. Results of a five-day performance verification test of the Electrovap system are presented and plans are included for the extended testing of the Electrovap to produce data applicable to the combination of electrolytic pretreatment with most final potable water recovery systems. Plans are also presented for a program to define the design requirements for combining the electrolytic pretreatment unit with a reverse osmosis final processing unit.

Four Weeks of β-alanine Supplementation Improves High-Intensity Game Activities in Water Polo.

PubMed

Brisola, Gabriel Motta Pinheiro; de Souza Malta, Elvis; Santiago, Paulo Roberto Pereira; Vieira, Luiz Henrique Palucci; Zagatto, Alessandro Moura

2018-04-13

The present study aimed to investigate whether four weeks of β-alanine supplementation improves total distance covered, distance covered and time spent in different speed zones, and sprint numbers during a simulated water polo game. The study design was double-blind, parallel and placebo controlled. Eleven male water polo players participated in the study, divided randomly into two homogeneous groups (placebo and β-alanine groups). The participants performed a simulated water polo game before and after the supplementation period (4 weeks). Participants received 4.8g∙day -1 of dextrose or β-alanine on the first ten days and 6.4g∙day -1 on the final 18 days. Only the β-alanine group presented a significant improvement in total sprint numbers compared to the pre-supplementation moment (PRE=7.8±5.2a.u.; POST=20.2±7.8a.u.; p=.002). Furthermore, β-alanine supplementation presented a likely beneficial effect on improving total distance covered (83%) and total time spent (81%) in zone 4 of speed (i.e., speed≥1.8m∙s -1 ). There was no significant interaction effect (group×time) for any variable. To conclude, four weeks of β-alanine supplementation can slightly improve sprint numbers and had a likely beneficial effect on improving distance covered and time spent in zone 4 of speed in a water polo simulated game.

Lessons from Practice: Designing Tools to Facilitate Individualized Support for Quitting Smoking

PubMed Central

Bhattacharya, Arpita; Vilardaga, Roger; Kientz, Julie A.; Munson, Sean A.

2017-01-01

Many health care providers, with a variety of trainings, counsel clients on quitting smoking on a day-to-day basis. In their clinical practice, they draw from and adapt guidelines and research-based strategies to fit individual client situations and challenges. Designers of technologies to support quitting smoking can learn from these real world practices to create tools that better adapt to individual differences. We present findings from interviews with 28 providers with diverse experiences in smoking cessation counselling. Through analysis of their individualization strategies, challenges, and perceptions of technology, we find that providers: (1) individualize context appropriate coping strategies by involving clients in brainstorming, (2) emphasize the need to support nicotine withdrawal in clients, (3) mitigate social triggers and mediate social support for clients, and (4) need to navigate dependencies with other providers for managing medications and comorbid health conditions of clients. With this empirical understanding, we extend the discussion on the design of technology to support quitting smoking, highlight current barriers to individualization, and suggest future opportunities to address these barriers. PMID:29123362

Design, operation, and safety of single-room interventional MRI suites: practical experience from two centers.

PubMed

White, Mark J; Thornton, John S; Hawkes, David J; Hill, Derek L G; Kitchen, Neil; Mancini, Laura; McEvoy, Andrew W; Razavi, Reza; Wilson, Sally; Yousry, Tarek; Keevil, Stephen F

2015-01-01

The design and operation of a facility in which a magnetic resonance imaging (MRI) scanner is incorporated into a room used for surgical or endovascular cardiac interventions presents several challenges. MR safety must be maintained in the presence of a much wider variety of equipment than is found in a diagnostic unit, and of staff unfamiliar with the MRI environment, without compromising the safety and practicality of the interventional procedure. Both the MR-guided cardiac interventional unit at Kings College London and the intraoperative imaging suite at the National Hospital for Neurology and Neurosurgery are single-room interventional facilities incorporating 1.5 T cylindrical-bore MRI scanners. The two units employ similar strategies to maintain MR safety, both in original design and day-to-day operational workflows, and between them over a decade of incident-free practice has been accumulated. This article outlines these strategies, highlighting both similarities and differences between the units, as well as some lessons learned and resulting procedural changes made in both units since installation. © 2014 Wiley Periodicals, Inc.

Methods and Strategies: Derby Design Day

ERIC Educational Resources Information Center

Kennedy, Katheryn

2013-01-01

In this article the author describes the "Derby Design Day" project--a project that paired high school honors physics students with second-grade children for a design challenge and competition. The overall project goals were to discover whether collaboration in a design process would: (1) increase an interest in science; (2) enhance the…

Application of the self-generation effect to the learning of Blissymbols by persons presenting with a severe aphasia.

PubMed

Rajaram, Priya; Alant, Erna; Dada, Shakila

2012-06-01

This study investigated the application of the self-generation effect to enhance the recognition and retention of Blissymbols in persons with severe aphasia. A 2×2×3 factorial design of two treatment types (self-generation and non-generation) was used to teach two sets of Blissymbols. These were administered during 3 training days, between which were withdrawal periods of 1 day and 7 days. Recognition and retention probes were administered at intervals during the training. ANOVA analysis showed that the self-generation treatment produced no immediate recognition advantage; however, better retention of symbol recognition may have occurred over time. Hence, the potential application of the self-generation effect in enhancing the retention of Blissymbols in persons with severe aphasia may warrant further investigation.

Research plan for establishing the effects of time varying noise exposures on community annoyance and acceptability

NASA Technical Reports Server (NTRS)

Borsky, P. N.

1980-01-01

The design of a community noise survey to determine the effects of time varying noise exposures in residential communities is presented. Complex physical and human variables involved in the health and welfare effects of environmental noise and the number-level tradeoffs and time of day penalties are among the factors considered. Emphasis is placed on community reactions where noise exposures are equal in day or evening but differ in the night time, and the effects of ambient noise on more intense aircraft noise exposures. Thirteen different times of day and types of operation situations with exposed populations up to 8-10 miles from the airport are identified. A detailed personal interview questionnaire as well as specific instructions to interviewers are included.

Polyethylene glycol powder solution versus senna for bowel preparation for colonoscopy in children.

PubMed

Terry, Natalie A; Chen-Lim, Mei Lin; Ely, Elizabeth; Jatla, Muralidhar; Ciavardone, Denise; Esch, Salina; Farace, Lisa; Jannelli, Frances; Puma, Anita; Carlow, Dean; Mamula, Petar

2013-02-01

Safety and effectiveness of large-volume polyethylene glycol-based solution (PEG-ES) have been documented, but the taste and volume can be barriers to successful colonoscopy preparation. Efficacy and safety of small-volume electrolyte-free (PEG-P) preparation (Miralax) for colonoscopy preparation have been rarely studied, although presently used at many pediatric centers. The primary objective of the present study was to determine whether PEG-P results in a more efficacious and safe colonoscopy preparation as compared with senna. The study design was prospective, randomized, and single-blinded. Patients ages 6 to 21 years were randomized to a 2-day clean-out regimen of PEG-P at a dose of 1.5 g/kg divided twice per day for 2 days versus senna 15 mL daily (ages 6-12) or 30 mL daily (ages 12-21) for 2 days. Both preparations required 1 day of clear liquids whereas senna preparation required an additional day of full liquid diet. A blinded endoscopist graded the quality of preparation with a standardized cleanliness tool (Aronchick scale). Serum chemistry panels were obtained. Patients or parents rated symptoms and ease of preparation. The anticipated number of subjects was 166; however, the interim analysis demonstrated inferiority of senna preparation. Thirty patients were evaluated in the present study. Of the patients in the PEG-P arm, 88% (14/16) received an excellent/good score compared with 29% (4/14), with the senna preparation (P = 0.0022). Both preparations were well-tolerated by patient-graded ease of preparation. Demographics and laboratory values did not differ significantly across the 2 groups. No serious adverse events were noted. PEG-P is an effective colonoscopy preparation whereas senna preparation was insufficient. Both were well-tolerated and appear safe in a pediatric population.

Effect of Morinda citrifolia (Noni) Fruit Juice on High Fat Diet Induced Dyslipidemia in Rats.

PubMed

Shoeb, Ahsan; Alwar, M C; Shenoy, Preethi J; Gokul, P

2016-04-01

The medicinal value of Morinda citrifolia L. (commonly known as Noni) has been explored in ancient folk remedies with a wide range of therapeutic utility, including antibacterial, antiviral, antifungal, antitumour, analgesic, hypotensive, anti-inflammatory and immune enhancing effects. The present study was designed to evaluate the effects of Noni fruit juice on serum lipid profile in high fat diet induced murine model of dyslipidemia. Hyperlipidemia was induced by feeding a cholesterol rich high fat diet for 45 days in wistar albino rats of either sex (n=8). Noni fruit juice administered at 50mg/kg/day and 100mg/kg/day, per oral, was compared with the standard drug Atorvastatin (10mg/kg/day, oral) fed for the latter 30 days. The blood samples were then sent for complete blood lipid profile, after 30 days of treatment. The data presented as mean ± SEM was analyzed using one-way ANOVA followed by Tukey's post-hoc test. The p <0.05 was considered as statistically significant. The Noni fruit juice treated group showed a significant decrease in the total cholesterol, triglycerides and very low density lipoprotein - Cholesterol at both the doses when compared to the disease control (p<0.05). However, the decrease in the TC (102.75±9.79 mg/dL) and LDL-C (47.87±7.47 mg/dL) levels observed with the noni fruit juice at the 50mg/kg dose employed, failed to show a statistical significance when compared to atorvastatin. The present study provides evidence for the hypolipidemic activity of Noni fruit juice in high fat diet induced hyperlipidemia in rats.

Using environmental engineering to increase hand hygiene compliance: a cross-over study protocol.

PubMed

Schmidtke, Kelly Ann; Aujla, Navneet; Marshall, Tom; Hussain, Abid; Hodgkinson, Gerard P; Arheart, Kristopher; Marti, Joachim; Birnbach, David J; Vlaev, Ivo

2017-09-11

Compliance with hand hygiene recommendations in hospital is typically less than 50%. Such low compliance inevitably contributes to hospital-acquired infections that negatively affect patients' well-being and hospitals' finances. The design of the present study is predicated on the assumption that most people who fail to clean their hands are not doing so intentionally, they just forget. The present study will test whether psychological priming can be used to increase the number of people who clean their hands on entering a ward. Here, we present the protocol for this study. The study will use a randomised cross-over design. During the study, each of four wards will be observed during four conditions: olfactory prime, visual prime, both primes and neither prime. Each condition will be experienced for 42 days followed by a 7-day washout period (total duration of trial=189 days). We will record the number of people who enter each ward and whether they clean their hands during observation sessions, the amount of cleaning material used from the dispensers each week and the number of hospital-acquired infections that occur in each period. The outcomes will be compared using a regression analysis. Following the initial trail, the most effective priming condition will be rolled out for 3 months in all the wards. Research ethics approval was obtained from the South Central-Oxford C Research Ethics Committee (16/SC/0554), the Health Regulatory Authority and the sponsor. ISRCTN (15397624); Edge ID 86357. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Finding Superman & Global Competitiveness: A Conversation with Arthur Levine & Watson Scott Swail. Policy Perspectives

ERIC Educational Resources Information Center

Levine, Arthur; Swail, Watson Scott

2014-01-01

On March 21 2013, the "Educational Policy Institute" held the first day of the EPI Forum on Education & the Economy in Orlando, Florida. The Forum was designed to discuss critical issues related to the nexus of education and the workforce. This document presents the transcribed session that featured two of the authors of the Teachers…

Getting Started: Preparation for the Teaching Programme. Additional Literacy Support. The National Literacy Strategy.

ERIC Educational Resources Information Center

Department for Education and Employment, London (England).

This Getting Started guide contains material presented at a two-day Additional Literacy Support (ALS) training course in the summer of 1999. ALS is designed to help pupils in Key Stage 2 who have already fallen behind in literacy, but who would not otherwise receive any additional support in this area. Each module includes a practical, high…

Problem Solving Techniques in Child Rearing: A Training Script for Parents of Young Children.

ERIC Educational Resources Information Center

Shure, Myrna B.; Spivack, George

Presented is a sequenced series of approximately 25 lessons designed to help mothers increase the interpersonal problem solving ability and behavioral adjustment of their 4- and 5-year-old children. It is explained that the program which takes 20 minutes per day over a 3 month period, combines an educational and preventive mental health approach.…

"Row, Row, Row Your Boat": Singing, Identity and Belonging in a Nursery

ERIC Educational Resources Information Center

Niland, Amanda

2015-01-01

The concept of belonging is widely recognised as a fundamental part of human development and a key element of early childhood curricula. The research presented here explores the role of singing in the development of children's sense of belonging in a day nursery for children aged from six months to two years. The research design incorporated…

Guidelines for a Training Program for Audiometric Technicians. Report of Working Group 66.

ERIC Educational Resources Information Center

Glorig, Aram, Ed.; And Others

The document outlines a course designed to train audiometric technicians who will conduct pure-tone conduction tests as part of a program on hearing conservation in noise. A minimum of two days is required for the completion of the course. The outline of the training program presents nine topics with an indication of the minimum time required for…

A Resource Guide for an Exploratory Curriculum for Three-Year Old Migrant Children.

ERIC Educational Resources Information Center

Hoffman, Stevie; Mottola, Niel

The rational for the curriculum design for three-year-old migrant children in an expanded-day educational program is presented. Consideration is given for each of the program phases, the learning environment, the rationale for a pre-service workshop and on-going in-service consultancy. This curriculum is based on the premise that, because of the…

"Recombinant Protein of the Day": Using Daily Student Presentations to Add Real-World Aspects to a Biotechnology Course

ERIC Educational Resources Information Center

Shaffer, Justin F.

2013-01-01

To provide a realistic view of the biotechnology industry for students, a novel course focusing on recombinant proteins and their importance in medicine, pharmaceuticals, industry, scientific research, and agriculture was developed. ''Designer Proteins and Society,'' an upper-division elective, was taught in the Fall 2012 semester to 16 junior,…

KENNEDY SPACE CENTER, FLA. - An overhead crane lifts the Mars Exploration Rover 2 (MER-2) entry vehicle from its stand to move it to a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - An overhead crane lifts the Mars Exploration Rover 2 (MER-2) entry vehicle from its stand to move it to a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

KENNEDY SPACE CENTER, FLA. - With help from workers, the overhead crane lowers the Mars Exploration Rover 2 (MER-2) entry vehicle onto a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - With help from workers, the overhead crane lowers the Mars Exploration Rover 2 (MER-2) entry vehicle onto a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

KENNEDY SPACE CENTER, FLA. - An overhead crane moves the Mars Exploration Rover 2 (MER-2) entry vehicle across the Payload Hazardous Servicing Facility toward a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - An overhead crane moves the Mars Exploration Rover 2 (MER-2) entry vehicle across the Payload Hazardous Servicing Facility toward a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

KENNEDY SPACE CENTER, FLA. - Workers in the Payload Hazardous Servicing Facility help guide the Mars Exploration Rover 2 (MER-2) entry vehicle toward a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - Workers in the Payload Hazardous Servicing Facility help guide the Mars Exploration Rover 2 (MER-2) entry vehicle toward a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

KENNEDY SPACE CENTER, FLA. - An overhead crane is in place to lift the Mars Exploration Rover 2 (MER-2) entry vehicle to move it to a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - An overhead crane is in place to lift the Mars Exploration Rover 2 (MER-2) entry vehicle to move it to a spin table for a dry-spin test. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch for MER-2 (MER-A) is scheduled for June 5.

Differential susceptibility of rats and guinea pigs to the ototoxic effects of ethyl benzene.

PubMed

Cappaert, Natalie L M; Klis, Sjaak F L; Muijser, Hans; Kulig, Beverly M; Ravensberg, Luco C; Smoorenburg, Guido F

2002-01-01

The present study was designed to compare the ototoxic effects of volatile ethyl benzene in guinea pigs and rats. Rats showed deteriorated auditory thresholds in the mid-frequency range, based on electrocochleography, after 550-ppm ethyl benzene (8 h/day, 5 days). Outer hair cell (OHC) loss was found in the corresponding cochlear regions. In contrast, guinea pigs showed no threshold shifts and no OHC loss after exposure to much higher ethyl benzene levels (2500 ppm, 6 h/day, 5 days). Subsequently, a limited study (four rats and four guinea pigs) was performed in an attempt to understand these differences in susceptibility. Ethyl benzene concentration in blood was determined in both species after exposure to 500-ppm ethyl benzene (8 h/day, 3 days). At the end of the first day, blood of the rats contained 23.2+/-0.8-microg/ml ethyl benzene, whereas the concentration in guinea pig blood was 2.8+/-0.1 microg/ml. After 3 days, the concentration in both species decreased with respect to the first day, but the ethyl benzene concentration in rat blood was still 4.3 times higher than that in guinea pig blood. Thus, the difference in susceptibility between the species may be related to the ethyl benzene concentration in blood.

Tissue-specific uptake and bioconcentration of the oral contraceptive norethindrone in two freshwater fishes.

PubMed

Nallani, Gopinath C; Paulos, Peter M; Venables, Barney J; Edziyie, Regina E; Constantine, Lisa A; Huggett, Duane B

2012-02-01

The environmental presence of the oral contraceptive norethindrone (NET) has been reported and shown to have reproductive effects in fish at environmentally realistic exposure levels. The current study examined bioconcentration potential of NET in fathead minnow (Pimephales promelas) and channel catfish (Ictalurus punctatus). Fathead minnows were exposed to 50 μg/l NET for 28 days and allowed to depurate in clean water for 14 days. In a minimized 14-day test design, catfish were exposed to 100 μg/l NET for 7 days followed by 7-day depuration. In the fathead test, tissues (muscle, liver, and kidneys) were sampled during the uptake (days 1, 3, 7, 14, and 28) and depuration (days 35 and 42) phases. In the catfish test, muscle, liver, gill, brain, and plasma were collected during the uptake (days 1, 3, and 7) and depuration (day 14) stages. NET tissue levels were determined by gas chromatography-mass spectrometry (GC-MS). Accumulation of NET in tissues was greatest in liver followed by plasma, gill, brain, and muscle. Tissue-specific bioconcentration factors (BCFs) ranged from 2.6 to 40.8. Although NET has been reported to elicit reproductive effects in fish, the present study indicated a low potential to bioconcentrate in aquatic biota.

Super-large optical gyroscopes for applications in geodesy and seismology: state-of-the-art and development prospects

DOE Office of Scientific and Technical Information (OSTI.GOV)

Velikoseltsev, A A; Luk'yanov, D P; Vinogradov, V I

2014-12-31

A brief survey of the history of the invention and development of super-large laser gyroscopes (SLLGs) is presented. The basic results achieved using SLLGs in geodesy, seismology, fundamental physics and other fields are summarised. The concept of SLLG design, specific features of construction and implementation are considered, as well as the prospects of applying the present-day optical technologies to laser gyroscope engineering. The possibilities of using fibre-optical gyroscopes in seismologic studies are analysed and the results of preliminary experimental studies are presented. (laser gyroscopes)

System analysis approach to deriving design criteria (Loads) for Space Shuttle and its payloads. Volume 2: Typical examples

NASA Technical Reports Server (NTRS)

Ryan, R. S.; Bullock, T.; Holland, W. B.; Kross, D. A.; Kiefling, L. A.

1981-01-01

The achievement of an optimized design from the system standpoint under the low cost, high risk constraints of the present day environment was analyzed. Space Shuttle illustrates the requirement for an analysis approach that considers all major disciplines (coupling between structures control, propulsion, thermal, aeroelastic, and performance), simultaneously. The Space Shuttle and certain payloads, Space Telescope and Spacelab, are examined. The requirements for system analysis approaches and criteria, including dynamic modeling requirements, test requirements, control requirements, and the resulting design verification approaches are illustrated. A survey of the problem, potential approaches available as solutions, implications for future systems, and projected technology development areas are addressed.

[Reference values of iron, iodine, zinc, selenium, copper, molybdenum, vitamin C, vitamin E, vitamin K, carotenoids and polyphenols for the Venezuelan population].

PubMed

García-Casal, Maria Nieves; Landaeta, Maritza; Adrianza de Baptista, Gertrudis; Murillo, Carolain; Rincón, Mariela; Bou Rached, Lizet; Bilbao, Arantza; Anderson, Hazel; García, Doris; Franquiz, Julia; Puche, Rafael; Garcia, Omar; Quintero, Yurimay; Peña-Rosas, Juan Pablo

2013-12-01

The review on iron, iodine, zinc, selenium, copper, molybdenum, vitamin C, vitamin E, vitamin K, carotenoids and polyphenols recommendations for Venezuela comprise the definitions adopted worldwide known as Dietary Reference Intakes (DRIs) that include Recommended Dietary Allowance (RDA), Estimated Average Requirement (EAR), Adequate Intake (AI) and Tolerable Upper Intake Levels (UL). The RDA for iron: 11 mg/day for infants < 1 year of age, 7-10 mg/day for children, 8-11 mg/day for males, 8-18 mg/day for females and 27 mg/day during pregnancy. RDA for iodine: 110-130 microg/day for infants, 90-120 microg/ day for children and adolescents, 150 microg/day for adults, 220 microg/ day for pregnancy and 290 microg/day during lactation. RDA Zinc: 2-3 mg/day for infants, 3-5 mg/day for children, 8-11 mg/day for male adolescents and adults, 8-9 mg/day for female adolescents and adults, 12 mg/day during pregnancy and 13 mg/day for lactation. RDA Vitamin C: 40-50 mg/day for infants, 15-45 mg/ day for children, 75 mg/day for male adolescents, 65 mg/day for female adolescents, 90 mg/day for adult males, 75 mg/day for adult females, 80-85 mg/day during pregnancy and 115-120 mg/day during lactation. Recommendations for copper, selenium, molybdenum, vitamins E, K, carotenoids and polyphenols are also presented. These recommendations will help to design adequate and efficient policies that could help to avoid or to treat the consequences derived from the deficiency or the excess of these nutrients.

Subjective Response to Simulated Sonic Booms in Homes

NASA Technical Reports Server (NTRS)

McCurdy, David A.; Brown, Sherilyn A.

1996-01-01

One of the environmental issues affecting the development of a second-generation supersonic commercial transport is the impact of sonic booms on people. Aircraft designers are attempting to design the transport to produce sonic boom signatures that will have minimum impact on the public. Current supersonic commercial aircraft produce an 'N-wave' sonic boom pressure signature that is considered unacceptable by the public. This has resulted in first-generation supersonic transports being banned from flying supersonic over land in the United States, a severe economic constraint. By tailoring aircraft volume and lift distributions, designers hope to produce sonic boom signatures having specific shapes other than 'N-wave' that may be more acceptable to the public. As part of the effort to develop a second-generation supersonic commercial transport, Langley Research Center is conducting research to study people's subjective response to sonic booms. As part of that research, a system was developed for performing studies of the subjective response of people to the occurrence of simulated sonic booms in their homes. The In-Home Noise Generation/Response System (IHONORS) provides a degree of situational realism not available in the laboratory and a degree of control over the noise exposure not found in community surveys. The computer-controlled audio system generates the simulated sonic booms, measures the noise levels, and records the subjects' ratings and can be placed and operated in individual homes for extended periods of time. The system was used to conduct an in-home study of subjective response to simulated sonic booms. The primary objective of the study was to determine the effect on annoyance of the number of sonic boom occurrences in a realistic environment. The effects on annoyance of several other parameters were also examined. Initially, data analyses were based on all the data collected. However, further analyser found that test subjects adapted to the sonic booms during the first few days of exposure. The first eight days of each testing period consisted of eight introductory exposures that were repeated on randomly selected days later in the testing period. Comparison of the introductory exposures with their repeats indicated that the test subjects adapted to the new sonic boom noise environment during the first days of the testing period. Because of the adaptation occurring, the introductory days were deleted from the ds set and the analyses redone. This paper presents the updated analyses. Elimination of the introductory days did not significantly affect the results and conclusions of the initial analyses. This paper also presents analyses of the effects on annoyance of additional factors in the study not previously examined.

Does presentation at the Registrars' Papers Day predict future publication?

PubMed

Wong, Shing W; Crowe, Philip J

2006-06-01

There are research requirements for trainees to be eligible to present for their final examinations (Fellowship of Royal Australasian College of Surgeons, FRACS). One option is the presentation of a paper or poster at a meeting of which abstracts are subject to review and selection. This includes presentation at the annual Registrars' Papers Day (RPD) in New South Wales. There has been some debate surrounding whether research requirements are fulfilled by presentation at such meetings. Publication in a peer-reviewed journal should be the ultimate aim. A high publication rate will validate the quality of the meeting. All abstracts submitted to the RPD in 1998 and 1999 were analysed. A Medline search was performed in 2005 to identify publication of these presentations in a peer-reviewed journal. Variables of the study that were potentially predictive of subsequent publication were analysed. This included type of presentation, surgical specialty, clinical or laboratory-based study, study design (prospective or retrospective) and sample size. Chi-squared test with Yates' continuity correction was used to compare two independent proportions and significance was set at P < 0.05. The publication rates were: oral presentations 50% (17/34), poster presentations 39% (9/23) and rejected presentations 20% (2/10). The mean and median time to publication was 23.8 and 21.0 months. Prospective design was the only variable identified to have a statistically significant effect on the publication rate (P < 0.002). The most common publishing journal was the Australian and New Zealand Journal of Surgery (12 of 26). Overall consistency (author and study sample consistency) from presentation to publication was 32%. The overall 46% publication rate of this state-based trainees-organized meeting compares favourably with international meetings. The research requirement of the Royal Australasian College of Surgeons (RACS), which includes presentation at the RPD in New South Wales, produces good quality papers for publication.

An intensive longitudinal examination of daily physical activity and sleep in midlife women.

PubMed

Kishida, Moé; Elavsky, Steriani

2016-03-01

Previous research examining physical activity (PA) and sleep link has largely ignored the day-to-day variability that is present in these 2 health behaviors, and few studies have addressed this relation using objective assessments of PA and sleep. Through an intensive longitudinal design, the present study aimed: (1) to elucidate the reciprocal associations between PA and sleep; and (2) to better understand the role of body mass index (BMI) in these 2 health behaviors. Community-dwelling midlife women (N = 103; M = 53, age range= 40-60 years) wore an accelerometer for the objective assessment of PA and sleep for 21 days. A series of multilevel models were estimated to test concurrent and lagged associations between PA (activity counts, moderate-to-vigorous PA) and sleep (total sleep time [TST], sleep efficiency, sleep fragmentation indices). In concurrent, same-day analyses, a positive association emerged between PA and sleep such that as activity counts increased during the day, TST at night also increased (P < .05). In lagged analyses examining next-day effect of sleep on PA, a negative association was found such that greater TST on a given night was associated with less moderate-to-vigorous PA the subsequent day (P < .05). A moderation effect by BMI was also observed such that women with a high BMI engaging in overall lower levels of PA demonstrated poorer-quality sleep. The data suggest that leading a physically active lifestyle may have protective effects on sleep, particularly for overweight and obese women. Published by Elsevier Inc.

A Comparison of Nannochloropsis salina Growth Performance in Two Outdoor Pond Designs: Conventional Raceways versus the ARID Pond with Superior Temperature Management

DOE PAGES

Crowe, Braden; Attalah, Said; Agrawal, Shweta; ...

2012-01-01

The present study examines how climatic conditions and pond design affect the growth performance of microalgae. From January to April of 2011, outdoor batch cultures of Nannochloropsis salina were grown in three replicate 780 L conventional raceways, as well as in an experimental 7500 L algae raceway integrated design (ARID) pond. The ARID culture system utilizes a series of 8-20 cm deep basins and a 1.5 m deep canal to enhance light exposure and mitigate temperature variations and extremes. The ARID culture reached the stationary phase 27 days earlier than the conventional raceways, which can be attributed to its superiormore » temperature management and shallower basins. On a night when the air temperature dropped to -9°C, the water temperature was 18°C higher in the ARID pond than in the conventional raceways. Lipid and fatty acid content ranged from 16 to 25% and from 5 to15%, respectively, as a percentage of AFDW. Palmitic, palmitoleic, and eicosapentaenoic acids comprised the majority of fatty acids. While the ARID culture system achieved nearly double the volumetric productivity relative to the conventional raceways (0.023 versus 0.013 g L -1day -1), areal biomass productivities were of similar magnitude in both pond systems (3.47 versus 3.34 g m -2day -1), suggesting that the ARID pond design has to be further optimized, most likely by increasing the culture depth or operating at higher cell densities while maintaining adequate mixing.« less

A comparison of Nannochloropsis salina growth performance in two outdoor pond designs: conventional raceways versus the ARID pond with superior temperature management

DOE Office of Scientific and Technical Information (OSTI.GOV)

Crowe, Braden J.; Attalah, Said; Agrawal, Shweta

2012-10-01

The present study examines how climatic conditions and pond design affect the growth performance of microalgae. From January to April of 2011, outdoor batch cultures of Nannochloropsis salina were grown in three replicate 780 L conventional raceways, as well as in an experimental 7500 L ARID (Algae Raceway Integrated Design) pond. The ARID culture system utilizes a series of 8 to 20 cm deep basins and a 1.5 m deep canal to enhance light exposure and mitigate temperature variations and extremes. The ARID culture reached the stationary phase 27 days earlier than the conventional raceways, which can be attributed tomore » its superior temperature management and shallower basins. On a night when the air temperature dropped to -9 °C, the water temperature was 18 °C higher in the ARID pond than in the conventional raceways. Lipid and fatty acid content ranged from 16 - 25 % and 5 - 15 %, respectively, as a percentage of AFDW. Palmitic, palmitoleic, and eicosapentaenoic acid comprised the majority of fatty acids. While the ARID culture system achieved nearly double the volumetric productivity relative to the conventional raceways (0.023 vs 0.013 g L-1day-1), areal biomass productivities were of similar magnitude in both pond systems (3.34 vs. 3.47 g m-2day-1), suggesting that the ARID pond design has to be further optimized, most likely by increasing the culture depth or operating at higher cell densities while maintaining adequate mixing.« less

Operation and maintenance requirements of the Army Remotely Piloted Vehicle (RPV)

NASA Technical Reports Server (NTRS)

1983-01-01

The Remotely Piloted Vehicle (RPV) system is being developed to provide the Army with a target acquistion, target location, and laser designation capability that will significantly enhance the effectiveness of the artillery. Iterative analyses of the manpower, personnel, and training (MPT) requirements for an RPV system configured to accommodate both a daylight television and a forward looking infrared (FLIR) mission payload subsystem (FMPS) and related support subsystems are examined. Additionally, this analysis incorporates a 24 hour-a-day operational scenario. Therefore, the information presented was developed with a view towards delineating the differences (or deltas) imposed by the new requirements resulting from FMPS/24 hour operating day functions.

[The recommendations regarding non-ST segment elevation acute coronary syndrome have been reviewed. SEMICYUC. Spanish Society for Intensive Medicine, Critical Care and Coronary Units].

PubMed

Civeira Murillo, E; Del Nogal Saez, F; Alvarez Ruiz, A P; Ferrero Zorita, J; Alcantara, A G; Aguado, G H; López Messa, J B; Montón Rodríguez, J A

2010-01-01

These recommendations are designed to be of assistance to doctors in ICUs when making first evaluations of these patients. They are mainly intended to assist with early diagnosis, risk stratification and initial treatment. The need for individualised treatment is at present one of the main objectives in the management of Acute Coronary Syndrome (ACS), with or without ST elevation, and this is why we believe the recommendations should be of a predominantly practical nature, given that they affect decision making in the day to day practice of medicine. Copyright 2009. Published by Elsevier Espana.

Clinical review: The critical care management of the burn patient

PubMed Central

2013-01-01

Between 4 and 22% of burn patients presenting to the emergency department are admitted to critical care. Burn injury is characterised by a hypermetabolic response with physiologic, catabolic and immune effects. Burn care has seen renewed interest in colloid resuscitation, a change in transfusion practice and the development of anti-catabolic therapies. A literature search was conducted with priority given to review articles, meta-analyses and well-designed large trials; paediatric studies were included where adult studies were lacking with the aim to review the advances in adult intensive care burn management and place them in the general context of day-to-day practical burn management. PMID:24093225

Frequency and duration of interval training programs and changes in aerobic power

NASA Technical Reports Server (NTRS)

Fox, E. L.; Bartels, R. L.; Obrien, R.; Bason, R.; Mathews, D. K.; Billings, C. E.

1975-01-01

The present study was designed to ascertain whether a training frequency of 2 days/wk for a 7- and 13-wk interval training program would produce improvement in maximal aerobic power comparable to that obtained from 7- and 13-wk programs of the same intensity consisting of 4 training days/wk. After training, there was a significant increase in maximal aerobic power that was independent of both training frequency and duration. Maximal heart rate was significantly decreased following training. Submaximal aerobic power did not change with training, but submaximal heart rate decreased significantly with greater decreases the more frequent and the longer the training.

Air Traffic Sector Configuration Change Frequency

NASA Technical Reports Server (NTRS)

Chatterji, Gano B.; Drew, Michael

2010-01-01

A Mixed Integer Linear Programming method is used for creating sectors in Fort Worth, Cleveland, and Los Angeles centers based on several days of good-weather traffic data. The performance of these sectors is studied when they are subjected to traffic data from different days. Additionally, the advantage of using different sector designs at different times of day with varying traffic loads is examined. Specifically, traffic data from 10 days are used for design, and 47 other days are played back to test if the traffic-counts stay below the design values used in creating the partitions. The primary findings of this study are as follows. Sectors created with traffic from good-weather days can be used on other good-weather days. Sector configurations created with two hours of traffic can be used for 6 to 12 hours without exceeding the peak-count requirement. Compared to using a single configuration for the entire day, most of the sector-hour reduction is achieved by using two sector configurations -one during daytime hours and one during nighttime hours.

Efficacy and tolerability of a polysaccharide-resin-honey based cough syrup as compared to carbocysteine syrup for children with colds: a randomized, single-blinded, multicenter study.

PubMed

Cohen, Herman Avner; Hoshen, Moshe; Gur, Shmuel; Bahir, Arie; Laks, Yoseph; Blau, Hannah

2017-02-01

Available pediatric treatments for acute cough are limited by lack of demonstrated efficacy. The objective of this trial is to compare the effects of a polysaccharide-resin-honey based cough syrup, and carbocysteine syrups on nocturnal and daytime cough associated with childhood upper respiratory tract infections (URIs). Using a single-blind randomization design, the study recruited children from 4 general pediatric community clinics. Participants included 150 children aged 2 to 5 years with an URI, nocturnal and daytime cough and illness duration of ≤7 days. To be eligible, children had to be free of medication on the day before presentation. A survey was administered to parents on 4 consecutive days beginning from the day of presentation in clinic. Children received the study preparation on the first evening and then 3 times per day for 3 further days. Main outcome measures were cough frequency, cough severity, bothersome nature of cough, and quality of sleep for both child and parent. Both preparations were well tolerated and cough improved over the study period. After one night and on all survey days, there was a significantly better result for polysaccharide-resin-honey (P<0.05) for all the main outcome measures. The trend of improvement over the 4 days was steeper for polysaccharide-resin-honey (P<0.05) with regards to all cough parameters. Both polysaccharide-resin-honey and carbocysteine cough syrups were well tolerated in children over 2 years of age. The polysaccharide-resin-honey syrup was associated with a more rapid and greater improvement in all clinical cough symptoms measured, beginning from the first night of therapy. Both nocturnal and daytime cough improved, as did sleep quality for both children and parents.

Flexible weapons architecture design

NASA Astrophysics Data System (ADS)

Pyant, William C., III

Present day air-delivered weapons are of a closed architecture, with little to no ability to tailor the weapon for the individual engagement. The closed architectures require weaponeers to make the target fit the weapon instead of fitting the individual weapons to a target. The concept of a flexible weapons aims to modularize weapons design using an open architecture shell into which different modules are inserted to achieve the desired target fractional damage while reducing cost and civilian casualties. This thesis shows that the architecture design factors of damage mechanism, fusing, weapons weight, guidance, and propulsion are significant in enhancing weapon performance objectives, and would benefit from modularization. Additionally, this thesis constructs an algorithm that can be used to design a weapon set for a particular target class based on these modular components.

Centroid stabilization in alignment of FOA corner cube: designing of a matched filter

NASA Astrophysics Data System (ADS)

Awwal, Abdul; Wilhelmsen, Karl; Roberts, Randy; Leach, Richard; Miller Kamm, Victoria; Ngo, Tony; Lowe-Webb, Roger

2015-02-01

The current automation of image-based alignment of NIF high energy laser beams is providing the capability of executing multiple target shots per day. An important aspect of performing multiple shots in a day is to reduce additional time spent aligning specific beams due to perturbations in those beam images. One such alignment is beam centration through the second and third harmonic generating crystals in the final optics assembly (FOA), which employs two retro-reflecting corner cubes to represent the beam center. The FOA houses the frequency conversion crystals for third harmonic generation as the beams enters the target chamber. Beam-to-beam variations and systematic beam changes over time in the FOA corner-cube images can lead to a reduction in accuracy as well as increased convergence durations for the template based centroid detector. This work presents a systematic approach of maintaining FOA corner cube centroid templates so that stable position estimation is applied thereby leading to fast convergence of alignment control loops. In the matched filtering approach, a template is designed based on most recent images taken in the last 60 days. The results show that new filter reduces the divergence of the position estimation of FOA images.

Harpicon camera for HDTV

NASA Astrophysics Data System (ADS)

Tanada, Jun

1992-08-01

Ikegami has been involved in broadcast equipment ever since it was established as a company. In conjunction with NHK it has brought forth countless television cameras, from black-and-white cameras to color cameras, HDTV cameras, and special-purpose cameras. In the early days of HDTV (high-definition television, also known as "High Vision") cameras the specifications were different from those for the cameras of the present-day system, and cameras using all kinds of components, having different arrangements of components, and having different appearances were developed into products, with time spent on experimentation, design, fabrication, adjustment, and inspection. But recently the knowhow built up thus far in components, , printed circuit boards, and wiring methods has been incorporated in camera fabrication, making it possible to make HDTV cameras by metbods similar to the present system. In addition, more-efficient production, lower costs, and better after-sales service are being achieved by using the same circuits, components, mechanism parts, and software for both HDTV cameras and cameras that operate by the present system.

Collective futures: how projections about the future of society are related to actions and attitudes supporting social change.

PubMed

Bain, Paul G; Hornsey, Matthew J; Bongiorno, Renata; Kashima, Yoshihisa; Crimston, Daniel

2013-04-01

We identified the active ingredients in people's visions of society's future ("collective futures") that could drive political behavior in the present. In eight studies (N = 595), people imagined society in 2050 where climate change was mitigated (Study 1), abortion laws relaxed (Study 2), marijuana legalized (Study 3), or the power of different religious groups had increased (Studies 4-8). Participants rated how this future society would differ from today in terms of societal-level dysfunction and development (e.g., crime, inequality, education, technology), people's character (warmth, competence, morality), and their values (e.g., conservation, self-transcendence). These measures were related to present-day attitudes/intentions that would promote/prevent this future (e.g., act on climate change, vote for a Muslim politician). A projection about benevolence in society (i.e., warmth/morality of people's character) was the only dimension consistently and uniquely associated with present-day attitudes and intentions across contexts. Implications for social change theories, political communication, and policy design are discussed.

Exploring Biomimicry in the Students' Design Process

ERIC Educational Resources Information Center

Boga-Akyol, Miray; Timur-Ogut, Sebnem

2016-01-01

Since the very early days of history, human beings "designed" things by looking at nature. In our days, the use of nature in design has become more systematic and detailed. Although as old as humanity itself, use of nature especially in the field of design still offers novelty and often brings success in solving problems in a sustainable…

METHODS FOR INTEGRATING ENVIRONMENTAL CONSIDERATIONS INTO CHEMICAL PROCESS DESIGN DECISIONS

EPA Science Inventory

The objective of this cooperative agreement was to postulate a means by which an engineer could routinely include environmental considerations in day-to-day conceptual design problems; a means that could easily integrate with existing design processes, and thus avoid massive retr...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miller, M.; Kempner, L. Jr.; Mueller, W. III

The concept of an Expert System is not new. It has been around since the days of the early computers when scientists had dreams of robot automation to do everything from washing windows to automobile design. This paper discusses an application of an expert system and addresses software development issues and various levels of expert system development form a structural engineering viewpoint. An expert system designed to aid the structural engineer in first order inelastic analysis of latticed steel transmission powers is presented. The utilization of expert systems with large numerical analysis programs is discussed along with the software developmentmore » of such a system.« less

Micropole Undulators In Synchrotron Radiation Technology: Design And Construction Of A Submillimeter Period Prototype With A 3 Kilogauss Peak Field At SSRL

NASA Astrophysics Data System (ADS)

Tatchyn, Roman; Csonka, Paul

1986-01-01

The availability of undulators with submillimeter periods will profoundly affect the future development of soft x-ray sources and their attendant instrumentation. Outputs comparable to those of present-day conventional undulators, obtainable with much lower energy storage rings, is only one promising aspect of such devices. This paper critically examines some of the future prospects of such devices and describes the design and practical construction of a 1" long prototype consisting of 35 periods. A proposed experiment to test this device on a linac is described.

Hubble space telescope six-battery test bed

NASA Technical Reports Server (NTRS)

Pajak, J. A.; Bush, J. R., Jr.; Lanier, J. R., Jr.

1990-01-01

A test bed for a large space power system breadboard for the Hubble Space Telescope (HST) was designed and built to test the system under simulated orbital conditions. A discussion of the data acquisition and control subsystems designed to provide for continuous 24 hr per day operation and a general overview of the test bed is presented. The data acquisition and control subsystems provided the necessary monitoring and protection to assure safe shutdown with protection of test articles in case of loss of power or equipment failure over the life of the test (up to 5 years).

OSO-6 Orbiting Solar Observatory

NASA Technical Reports Server (NTRS)

1972-01-01

The description, development history, test history, and orbital performance analysis of the OSO-6 Orbiting Solar Observatory are presented. The OSO-6 Orbiting Solar Observatory was the sixth flight model of a series of scientific spacecraft designed to provide a stable platform for experiments engaged in the collection of solar and celestial radiation data. The design objective was 180 days of orbital operation. The OSO-6 has telemetered an enormous amount of very useful experiment and housekeeping data to GSFC ground stations. Observatory operation during the two-year reporting period was very successful except for some experiment instrument problems.

Human Mars Ascent Configuration and Design Sensitivities

NASA Technical Reports Server (NTRS)

Polsgrove, Tara P.; Gernhardt, Mike; Collins, Tim; Martin, John

2017-01-01

Human missions to Mars may utilize several small cabins where crew members could live for days up to a couple of weeks. At the end of a Mars surface mission the Mars Ascent Vehicle (MAV) crew cabin would carry the crew to their destination in orbit in a matter of hours or days. Other small cabins in support of a Mars mission would include pressurized rovers that allow crew members to travel great distances from their primary habitat on Mars while unconstrained by time limits of typical EVAs. An orbital crew taxi could allow for exploration of the moons of Mars with minimum impact to the primary Earth-Mars transportation systems. A common crew cabin design that can perform in each of these applications is desired and could reduce the overall mission cost. However, for the MAV, the crew cabin size and mass can have a large impact on vehicle design and performance. The total ascent vehicle mass drives performance requirements for the Mars descent systems and the Earth to Mars transportation elements. Minimizing MAV mass is a priority and minimizing the crew cabin size and mass is one way to do that. This paper explores the benefits and impacts of using a common crew cabin design for the MAV. Results of a MAV configuration trade study will be presented along with mass and performance estimates for the selected design.

Varenicline, low dose naltrexone, and their combination for heavy-drinking smokers: human laboratory findings.

PubMed

Ray, Lara A; Courtney, Kelly E; Ghahremani, Dara G; Miotto, Karen; Brody, Arthur; London, Edythe D

2014-10-01

Heavy-drinking smokers constitute a sizeable and hard-to-treat subgroup of smokers, for whom tailored smoking cessation therapies are not yet available. The present study used a double-blind, randomized, 2 × 2 medication design, testing varenicline alone (VAR; 1 mg twice daily), low dose naltrexone alone (L-NTX; 25 mg once daily), varenicline plus naltrexone, and placebo for effects on cigarette craving and subjective response to alcohol and cigarettes in a sample (n = 130) of heavy-drinking daily smokers (≥10 cigarettes/day). All participants were tested after a 9-day titration period designed to reach a steady state on the target medication. Testing was completed at 12 h of nicotine abstinence, after consuming a standard dose of alcohol (target breath alcohol concentration = 0.06 g/dl) and after smoking the first cigarette of the day. The combination of VAR + L-NTX was superior to placebo, and at times superior to monotherapy, in attenuating cigarette craving, cigarette and alcohol "high," and in reducing ad-lib consumption of both cigarettes and alcohol during the 9-day medication titration period. These preliminary findings indicate that clinical studies of the combination of VAR + L-NTX for heavy drinkers trying to quit smoking are warranted and may ultimately improve clinical care for this sizeable and treatment-resistant subgroup of smokers.

Flight Qualification of the NASA's Super Pressure Balloon

NASA Astrophysics Data System (ADS)

Cathey, Henry; Said, Magdi; Fairbrother, Debora

Designs of new balloons to support space science require a number of actual flights under various flight conditions to qualify them to as standard balloon flight offerings to the science community. Development of the new Super Pressure Balloon for the National Aeronautics and Space Administration’s Balloon Program Office has entailed employing new design, analysis, and production techniques to advance the state of the art. Some of these advances have been evolutionary steps and some have been revolutionary steps requiring a maturing understanding of the materials, designs, and manufacturing approaches. The NASA Super Pressure Balloon development end goal is to produce a flight vehicle that is qualified to carry a ton of science instrumentation, at an altitude greater than 33 km while maintaining a near constant pressure altitude for extended periods of up to 100 days, and at any latitude on the globe. The NASA’s Balloon Program Office has pursued this development in a carefully executed incremental approach by gradually increasing payload carrying capability and increasing balloon volume to reach these end goal. A very successful test flight of a ~200,700 m3 balloon was launch in late 2008 from Antarctica. This balloon flew for over 54 days at a constant altitude and circled the Antarctic continent almost three times. A larger balloon was flown from Antarctica in early 2011. This ~422,400 m3 flew at a constant altitude for 22 days making one circuit around Antarctica. Although the performance was nominal, the flight was terminated via command to recover high valued assets from the payload. The balloon designed to reach the program goals is a ~532,200 m3 pumpkin shaped Super Pressure Balloon. A test flight of this balloon was launched from the Swedish Space Corporation’s Esrange Balloon Launch Facilities near Kiruna, Sweden on 14 August, 2012. This flight was another success for this development program. Valuable information was gained from this short test flight by successfully demonstrated balloon vehicle performance, obtained a large amount of videos, measured balloon differential pressure, obtained temperature and altitude data, assessed structure strength through pressurization, and demonstrated the balloon vehicles altitude stability. This flight was the first of several to qualify this design for the science community. Results of the most recent flights will be presented. Some of the related material characterization testing which is vital to the balloon design development for the balloon will also be presented. Additionally, this paper will provide a current overview of the development and qualification approach pursued for the NASA’s Super Pressure Balloon. Future plans and goals of future test flights will also be presented. This will include the projected balloon volumes, payload capabilities, test flight locations, and proposed flight schedule.

Enhancing Quality of Life of Families Who Use Adult Day Services: Short- and Long-Term Effects of the Adult Day Services Plus Program

ERIC Educational Resources Information Center

Gitlin, Laura N.; Reever, Karen; Dennis, Marie P.; Mathieu, Esther; Hauck, Walter W.

2006-01-01

Purpose: This study examined the short- and long-term effects of Adult Day Services Plus (ADS Plus), a low-cost care management intervention designed to enhance family caregiver well-being, increase service utilization, and decrease nursing home placement of impaired older adults enrolled in adult day care. Design and Methods: We used a…

Recent Development of the Two-Stroke Engine. II - Design Features. 2; Design Features

NASA Technical Reports Server (NTRS)

Zeman, J.

1945-01-01

Completing the first paper dealing with charging methods and arrangements, the present paper discusses the design forms of two-stroke engines. Features which largely influence piston running are: (a) The shape and surface condition of the sliding parts. (b) The cylinder and piston materials. (c) Heat conditions in the piston, and lubrication. There is little essential difference between four-stroke and two-stroke engines with ordinary pistons. In large engines, for example, are always found separately cast or welded frames in which the stresses are taken up by tie rods. Twin piston and timing piston engines often differ from this design. Examples can be found in many engines of German or foreign make. Their methods of operation will be dealt with in the third part of the present paper, which also includes the bibliography. The development of two-stroke engine design is, of course, mainly concerned with such features as are inherently difficult to master; that is, the piston barrel and the design of the gudgeon pin bearing. Designers of four-stroke engines now-a-days experience approximately the same difficulties, since heat stresses have increased to the point of influencing conditions in the piston barrel. Features which notably affect this are: (a) The material. (b) Prevailing heat conditions.

A Guide for the Management of Special Education Programs. 3.0 Educational Simulations. Newday Operations Guide for Drug Dependent Minor Programs.

ERIC Educational Resources Information Center

Santa Cruz County Superintendent of Schools, CA.

Presented is the third component, Educational Simulations, of a special day class educational program for drug dependent minors. One objective of the project is said to have been the identification of instructional methods and materials suited to drug dependent minors. Educational games and simulations designed to provide practice in reading and…

[Current problems in the laboratory control of louse-borne typhus infection in Ukraine].

PubMed

Klymchuk, M D

1996-01-01

Surveys designed to study spread of typhus infection (persistent form and Brill's disease), and state of laboratory diagnosis in Ukraine showed an important role the laboratory diagnosis plays in the system of epidemiological surveillance aimed at preventing epidemic typhus. Main trends of activities on perfection of the system of laboratory control of the infection under present-day conditions are outlined.

Growing Our Own: A Longitudinal Evaluation of a Professional Development Program for Early-Career 4-H Professionals

ERIC Educational Resources Information Center

Varrella, Gary F.; Luckey, Brian P.; Baca, Jacqueline S.; Peters, Curt

2016-01-01

We present the results of a longitudinal evaluation of the Western Region 4-H Institute, a 5-day training program designed to enhance the skill sets of early-career Extension professionals organized around the 4-H professional research, knowledge, and competencies model. Programs such as this often are assessed for their short-term relevance and…

Space Shuttle Day-of-Launch Trajectory Design Operations

NASA Technical Reports Server (NTRS)

Harrington, Brian E.

2011-01-01

A top priority of any launch vehicle is to insert as much mass into the desired orbit as possible. This requirement must be traded against vehicle capability in terms of dynamic control, thermal constraints, and structural margins. The vehicle is certified to specific structural limits which will yield certain performance characteristics of mass to orbit. Some limits cannot be certified generically and must be checked with each mission design. The most sensitive limits require an assessment on the day-of-launch. To further minimize vehicle loads while maximizing vehicle performance, a day-of-launch trajectory can be designed. This design is optimized according to that day s wind and atmospheric conditions, which increase the probability of launch. The day-of-launch trajectory design and verification process is critical to the vehicle s safety. The Day-Of-Launch I-Load Update (DOLILU) is the process by which the National Aeronautics and Space Administration's (NASA) Space Shuttle Program tailors the vehicle steering commands to fit that day s environmental conditions and then rigorously verifies the integrated vehicle trajectory s loads, controls, and performance. This process has been successfully used for almost twenty years and shares many of the same elements with other launch vehicles that execute a day-of-launch trajectory design or day-of-launch trajectory verification. Weather balloon data is gathered at the launch site and transmitted to the Johnson Space Center s Mission Control. The vehicle s first stage trajectory is then adjusted to the measured wind and atmosphere data. The resultant trajectory must satisfy loads and controls constraints. Additionally, these assessments statistically protect for non-observed dispersions. One such dispersion is the change in the wind from the last measured balloon to launch time. This process is started in the hours before launch and is repeated several times as the launch count proceeds. Should the trajectory design not meet all constraint criteria, Shuttle would be No-Go for launch. This Shuttle methodology is very similar to other unmanned launch vehicles. By extension, this method would likely be employed for any future NASA launch vehicle. This paper will review the Shuttle s day-of-launch trajectory optimization and verification operations as an example of a more generic application of day-of-launch design and validation. With Shuttle s retirement, it is fitting to document the current state of this critical process and capture lessons learned to benefit current and future launch vehicle endeavors.

[Integrated intensive treatment of tinnitus: method and initial results].

PubMed

Mazurek, B; Georgiewa, P; Seydel, C; Haupt, H; Scherer, H; Klapp, B F; Reisshauer, A

2005-07-01

In recent years, no major advances have been made in understanding the mechanisms underlying the development of tinnitus. Hence, the present therapeutic strategies aim at decoupling the subconscious from the perception of tinnitus. Mindful of the lessons drawn from existing tinnitus retraining and desensitisation therapies, a new integrated day hospital strategy of treatment lasting 7-14 days has been developed at the Charité Hospital and is presented in the present paper. The strategy for treating tinnitus in the proximity of patient domicile is designed for patients who feel disturbed in their world of perception and their efficiency due to tinnitus and give evidence of mental and physical strain. In view of the etiologically non-uniform and multiple events connected with tinnitus, consideration was also given to the fact that somatic and psychosocial factors are equally involved. Therefore, therapy should aim at diagnosing and therapeutically influencing those psychosocial factors that reduce the hearing impression to such an extent that the affected persons suffer from strain. The first results of therapy-dependent changes of 46 patients suffering from chronic tinnitus are presented. The data were evaluated before and after 7 days of treatment and 6 months after the end of treatment. Immediately after the treatment, the scores of both the tinnitus questionnaire (Goebel and Hiller) and the subscales improved significantly. These results were maintained during the 6-month post-treatment period and even improved.

Manufacturing of diamond windows for synchrotron radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schildkamp, W.; Nikitina, L.

2012-09-15

A new diamond window construction is presented and explicit manufacturing details are given. This window will increase the power dissipation by about a factor of 4 over present day state of the art windows to absorb 600 W of power. This power will be generated by in-vacuum undulators with the storage ring ALBA operating at a design current of 400 mA. Extensive finite element (FE) calculations are included to predict the windows behavior accompanied by explanations for the chosen boundary conditions. A simple linear model was used to cross-check the FE calculations.

Mars Exploration Rovers: 4 Years on Mars

NASA Technical Reports Server (NTRS)

Landis, Geoffrey A.

2008-01-01

This January, the Mars Exploration Rovers "Spirit" and "Opportunity" are starting their fifth year of exploring the surface of Mars, well over ten times their nominal 90-day design lifetime. This lecture discusses the Mars Exploration Rovers, presents the current mission status for the extended mission, some of the most results from the mission and how it is affecting our current view of Mars, and briefly presents the plans for the coming NASA missions to the surface of Mars and concepts for exploration with robots and humans into the next decade, and beyond.

Short-term use of glucocorticoids and risk of peptic ulcer bleeding: a nationwide population-based case-crossover study.

PubMed

Tseng, C-L; Chen, Y-T; Huang, C-J; Luo, J-C; Peng, Y-L; Huang, D-F; Hou, M-C; Lin, H-C; Lee, F-Y

2015-09-01

Controversy exists regarding glucocorticoids therapy and the risk of peptic ulcer bleeding (PUB). The present study was undertaken to determine whether short-term use of glucocorticoids is associated with the occurrence of peptic ulcer bleeding. The records of adult patients hospitalised for newly diagnosed peptic ulcer bleeding from 2000 to 2012 were retrieved from the Taiwan National Health Insurance Research Database, a nationwide population-based registry system. The association between systemic glucocorticoids usage and peptic ulcer bleeding was determined with a conditional logistic regression model comparing cases and controls during time windows of 7, 14 and 28 days using a case-crossover design. Of the 8894 enrolled patients, the adjusted self-matched odds ratios for peptic ulcer bleeding after exposure to the glucocorticoids were 1.37 (95% CI: 1.12-1.68, P = 0.003) for the 7-day window, 1.66 (95% CI: 1.38-2.00, P < 0.001) for the 14-day window and 1.84 (95% CI: 1.57-2.16, P < 0.001) for the 28-day window. Moderate to high, but not low dose glucocorticoids (methylprednisolone <4 mg/day or its equivalence) were associated with an increased risk of peptic ulcer bleeding. Concomitant use of a nonselective nonsteroidal anti-inflammatory drug (NSAID) or aspirin further elevated the risk. However, it does not eliminate the effect of underlying diseases flare-up that may have placed the patients at risk for peptic ulcer bleeding in this kind of study design. Short-term (7-28 days) exposure to glucocorticoids is significantly associated with peptic ulcer bleeding; this risk seems dose-dependent and is higher when nonselective NSAIDs or aspirin are used concurrently. © 2015 John Wiley & Sons Ltd.

Everyday eating experiences of chocolate and non-chocolate snacks impact postprandial anxiety, energy and emotional states.

PubMed

Martin, François-Pierre J; Antille, Nicolas; Rezzi, Serge; Kochhar, Sunil

2012-06-01

Social and psychological stressors are both a part of daily life and are increasingly recognized as contributors to individual susceptibility to develop diseases and metabolic disorders. The present study investigated how snacks differing in sensory properties and presentation can influence ratings of affect in consumers with different levels of dispositional anxiety. This study examines the relationships between a pre-disposition to anxiety and food using a repeated exposures design with three interspersed test days over a period of two weeks. The study was conducted on ninety free-living male (n = 28) and female (n = 62) Dutch participants aged between 18 and 35 years old, with a BMI between 18 and 25 kg/m(2) and different anxiety trait levels assessed using State-Trait Anxiety Inventory tests. The study was randomized by age, gender, anxiety trait score, and followed a parallel open design. Three test products: dark chocolate, a milk chocolate snack and crackers with cheese spread (control), which differed in composition, sensory properties and presentation, were evaluated. Changes in self-reported anxiety, emotion, and energetic states were assessed as a function of eating the snacks just after consumption and up to one hour. The repeated exposure design over a period of two weeks enabled the investigations of potential cumulative effects of regular consumption of the food products. The milk chocolate snack resulted in the decrease of anxiety in high anxiety trait subjects, whereas dark chocolate and cheese and crackers respectively improved the anxiety level and the energetic state of low anxiety trait participants. The mood effects were not altered with repeated exposure, and the magnitude of changes was similar on each test day, which illustrates the repeatability of the effects of the food on subjective measures of postprandial wellness.

Everyday Eating Experiences of Chocolate and Non-Chocolate Snacks Impact Postprandial Anxiety, Energy and Emotional States

PubMed Central

Martin, François-Pierre J.; Antille, Nicolas; Rezzi, Serge; Kochhar, Sunil

2012-01-01

Social and psychological stressors are both a part of daily life and are increasingly recognized as contributors to individual susceptibility to develop diseases and metabolic disorders. The present study investigated how snacks differing in sensory properties and presentation can influence ratings of affect in consumers with different levels of dispositional anxiety. This study examines the relationships between a pre-disposition to anxiety and food using a repeated exposures design with three interspersed test days over a period of two weeks. The study was conducted on ninety free-living male (n = 28) and female (n = 62) Dutch participants aged between 18 and 35 years old, with a BMI between 18 and 25 kg/m2 and different anxiety trait levels assessed using State-Trait Anxiety Inventory tests. The study was randomized by age, gender, anxiety trait score, and followed a parallel open design. Three test products: dark chocolate, a milk chocolate snack and crackers with cheese spread (control), which differed in composition, sensory properties and presentation, were evaluated. Changes in self-reported anxiety, emotion, and energetic states were assessed as a function of eating the snacks just after consumption and up to one hour. The repeated exposure design over a period of two weeks enabled the investigations of potential cumulative effects of regular consumption of the food products. The milk chocolate snack resulted in the decrease of anxiety in high anxiety trait subjects, whereas dark chocolate and cheese and crackers respectively improved the anxiety level and the energetic state of low anxiety trait participants. The mood effects were not altered with repeated exposure, and the magnitude of changes was similar on each test day, which illustrates the repeatability of the effects of the food on subjective measures of postprandial wellness. PMID:22822453

Optimizing Sampling Design to Deal with Mist-Net Avoidance in Amazonian Birds and Bats

PubMed Central

Marques, João Tiago; Ramos Pereira, Maria J.; Marques, Tiago A.; Santos, Carlos David; Santana, Joana; Beja, Pedro; Palmeirim, Jorge M.

2013-01-01

Mist netting is a widely used technique to sample bird and bat assemblages. However, captures often decline with time because animals learn and avoid the locations of nets. This avoidance or net shyness can substantially decrease sampling efficiency. We quantified the day-to-day decline in captures of Amazonian birds and bats with mist nets set at the same location for four consecutive days. We also evaluated how net avoidance influences the efficiency of surveys under different logistic scenarios using re-sampling techniques. Net avoidance caused substantial declines in bird and bat captures, although more accentuated in the latter. Most of the decline occurred between the first and second days of netting: 28% in birds and 47% in bats. Captures of commoner species were more affected. The numbers of species detected also declined. Moving nets daily to minimize the avoidance effect increased captures by 30% in birds and 70% in bats. However, moving the location of nets may cause a reduction in netting time and captures. When moving the nets caused the loss of one netting day it was no longer advantageous to move the nets frequently. In bird surveys that could even decrease the number of individuals captured and species detected. Net avoidance can greatly affect sampling efficiency but adjustments in survey design can minimize this. Whenever nets can be moved without losing netting time and the objective is to capture many individuals, they should be moved daily. If the main objective is to survey species present then nets should still be moved for bats, but not for birds. However, if relocating nets causes a significant loss of netting time, moving them to reduce effects of shyness will not improve sampling efficiency in either group. Overall, our findings can improve the design of mist netting sampling strategies in other tropical areas. PMID:24058579

Neuroprotective mechanism of losartan and its interaction with nimesulide against chronic fatigue stress.

PubMed

Kumar, Anil; Singh, Barinder; Mishra, Jitendriya; Sah, Sangeeta Pilkhwal; Pottabathini, Raghavender

2015-12-01

Potential role of angiotensin-II and cyclooxygenase have been suggested in the pathophysiology of chronic fatigue stress. The present study has been designed to evaluate the neuroprotective effect of losartan and its interaction with nimesulide against chronic fatigue stress and related complications in mice. In the present study, male Laca mice (20-30 g) were subjected to running wheel activity test session (RWATS) for 6 min daily for 21 days. Losartan, nimesulide and their combinations were administered daily for 21 days, 45 min before being subjected to RWATS. Various behavioral and biochemical and neuroinflammatory mediators were assessed subsequently. 21 days RWATS treatment significantly decreased number of wheel rotations/6 min indicating fatigue stress like behaviors as compared to naive group. 21 days treatment with losartan (10 and 20 mg/kg, ip), nimesulide (5 and 10 mg/kg, po) and their combinations significantly improved behavior [increased number of wheel rotations, reversal of post-exercise fatigue, locomotor activity, antianxiety-like behavior (number of entries, latency to enter and time spent in mirror chamber), and memory performance (transfer latency in plus-maze performance task)], biochemical parameters (reduced serum corticosterone, brain lipid peroxidation, nitrite concentration, acetylcholinesterase activity, restored reduced glutathione levels and catalase activity) as compared to RWATS control. Besides, TNF-α, CRP levels were significantly attenuated by these drugs and their combinations as compared to control. The present study highlights the role of cyclooxygenase modulation in the neuroprotective effect of losartan against chronic fatigue stress-induced behavioral, biochemical and cellular alterations in mice.

Uncovering the Rosetta Stone: Report from the First Annual Conference on Key Elements in Translating Stroke Therapeutics from Pre-Clinical to Clinical.

PubMed

Bix, Gregory J; Fraser, Justin F; Mack, William J; Carmichael, S Thomas; Perez-Pinzon, Miguel; Offner, Halina; Sansing, Lauren; Bosetti, Francesca; Ayata, Cenk; Pennypacker, Keith R

2018-06-01

The first annual Stroke Translational Research Advancement Workshop (STRAW), entitled "Uncovering the Rosetta Stone: Key Elements in Translating Stroke Therapeutics from Pre-Clinical to Clinical" was held at the University of Kentucky on October 4-5, 2017. This workshop was organized by the Center for Advanced Translational Stroke Science. The workshop consisted of 2 days of activities. These included three presentations establishing the areas of research in stroke therapeutics, discussing the routes for translation from bench to bedside, and identifying successes and failures in the field. On day 2, grant funding opportunities and goals for the National Institute for Neurological Diseases and Stroke were presented. In addition, the meeting also included break-out sessions designed to connect researchers in areas of stroke, and to foster potential collaborations. Finally, the meeting concluded with an open discussion among attendees led by a panel of experts.

The Physics of Tokamak Start-up

DOE Office of Scientific and Technical Information (OSTI.GOV)

D. Mueller

Tokamak start-up on present-day devices usually relies on inductively induced voltage from a central solenoid. In some cases inductive startup is assisted with auxiliary power from electron cyclotron radio frequency heating. ITER, the National Spherical Torus eXperiment Upgrade and JT60, now under construction, will make use of the understanding gained from present-day devices to ensure successful start-up. Design of a spherical tokamak (ST) with DT capability for nuclear component testing would require an alternative to a central solenoid because the small central column in an ST has insufficient space to provide shielding for the insulators in the solenoid. Alternative start-upmore » techniques such as induction using outer poloidal field coils, electron Bernstein wave start-up, coaxial helicity injection and point source helicity injection have been used with success, but require demonstration of scaling to higher plasma current.« less

The physics of tokamak start-up

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mueller, D.

Tokamak start-up on present-day devices usually relies on inductively induced voltage from a central solenoid. In some cases, inductive startup is assisted with auxiliary power from electron cyclotron radio frequency heating. International Thermonuclear Experimental Reactor, the National Spherical Torus Experiment Upgrade and JT60, now under construction, will make use of the understanding gained from present-day devices to ensure successful start-up. Design of a spherical tokamak (ST) with DT capability for nuclear component testing would require an alternative to a central solenoid because the small central column in an ST has insufficient space to provide shielding for the insulators in themore » solenoid. Alternative start-up techniques such as induction using outer poloidal field coils, electron Bernstein wave start-up, coaxial helicity injection, and point source helicity injection have been used with success, but require demonstration of scaling to higher plasma current.« less

Estimating spawning times of Alligator Gar (Atractosteus spatula) in Lake Texoma, Oklahoma

USGS Publications Warehouse

Snow, Richard A.; Long, James M.

2015-01-01

In 2013, juvenile Alligator Gar were sampled in the reservoir-river interface of the Red River arm of Lake Texoma. The Red River, which flows 860 km along Oklahoma’s border with Texas, is the primary in-flow source of Lake Texoma, and is impounded by Denison Dam. Minifyke nets were deployed using an adaptive random cluster sampling design, which has been used to effectively sample rare species. Lapilli otoliths (one of the three pair of ear stones found within the inner ear of fish) were removed from juvenile Alligator Gar collected in July of 2013. Daily ages were estimated by counting the number of rings present, and spawn dates were back-calculated from date of capture and subtracting 8 days (3 days from spawn to hatch and 5 days from hatch to swimup when the first ring forms). Alligator Gar daily age estimation ranged from 50 to 63 days old since swim-up. Spawn dates corresponded to rising pool elevations of Lake Texoma and water pulses of tributaries.

Age matters: the effects of volatile organic compounds emitted by Trichoderma atroviride on plant growth.

PubMed

Lee, Samantha; Hung, Richard; Yap, Melanie; Bennett, Joan W

2015-06-01

Studying the effects of microbial volatile organic compounds (VOCs) on plant growth is challenging because the production of volatiles depends on many environmental factors. Adding to this complexity, the method of volatile exposure itself can lead to different responses in plants and may account for some of the contrasting results. In this work, we present an improved experimental design, a plate-within-a-plate method, to study the effects of VOCs produced by filamentous fungi. We demonstrate that the plant growth response to VOCs is dependent on the age of the plant and fungal cultures. Plants exposed to volatiles emitted by 5-day-old Trichoderma atroviride for 14 days exhibited inhibition, while plants exposed to other exposure conditions had growth promotion or no significant change. Using GC-MS, we compared fungal volatile emission of 5-day-old and 14-day-old T. atroviride. As the fungi aged, a few compounds were no longer detected, but 24 new compounds were discovered.

Elementary Students' Acquisition of Academic Vocabulary Through Engineering Design

NASA Astrophysics Data System (ADS)

Kugelmass, Rachel

This study examines how STEM (science, technology, engineering, and mathematics) inquiry-based learning through a hands-on engineering design can be beneficial in helping students acquire academic vocabulary. This research took place in a second grade dual- language classroom in a public, suburban elementary school. English language learners, students who speak Spanish at home, and native English speakers were evaluated in this study. Each day, students were presented with a general academic vocabulary focus word during an engineering design challenge. Vocabulary pre-tests and post-tests as well as observation field notes were used to evaluate the student's growth in reading and defining the focus academic vocabulary words. A quiz and KSB (knowledge and skill builder) packet were used to evaluate students' knowledge of science and math content and engineering design. The results of this study indicate that engineering design is an effective means for teaching academic vocabulary to students with varying levels of English proficiency.

Can people with Alzheimer's disease improve their day-to-day functioning with a tablet computer?

PubMed

Imbeault, Hélène; Langlois, Francis; Bocti, Christian; Gagnon, Lise; Bier, Nathalie

2018-07-01

New technologies, such as tablet computers, present great potential to support the day-to-day living of persons with Alzheimer's disease (AD). However, whether people with AD can learn how to use a tablet properly in daily life remains to be demonstrated. A single case study was conducted with a 65-year-old woman with AD. A specific and structured intervention tailored to her needs was conceptualised for the use of a calendar application on a tablet computer according to the following learning stages: Acquisition, Application and Adaptation. In spite of her severe episodic memory deficit, she showed progressive learning of the tablet application during the intervention phase. Furthermore, data compiled over 12 months post-use show that she used the tablet successfully in her day-to-day life. She was even able to transfer her newly acquired ability to other available applications designed to monitor regular purchases, consult various recipes and play games. Tablet computers thereby offer a promising avenue for cognitive rehabilitation for persons with AD. This success was mainly achieved through a one-on-one individual programme tailored to this person. The limits and constraints of utilising tablet computers for persons with AD are discussed.

An industrial approach to design compelling VR and AR experience

NASA Astrophysics Data System (ADS)

Richir, Simon; Fuchs, Philippe; Lourdeaux, Domitile; Buche, Cédric; Querrec, Ronan

2013-03-01

The convergence of technologies currently observed in the field of VR, AR, robotics and consumer electronic reinforces the trend of new applications appearing every day. But when transferring knowledge acquired from research to businesses, research laboratories are often at a loss because of a lack of knowledge of the design and integration processes in creating an industrial scale product. In fact, the innovation approaches that take a good idea from the laboratory to a successful industrial product are often little known to researchers. The objective of this paper is to present the results of the work of several research teams that have finalized a working method for researchers and manufacturers that allow them to design virtual or augmented reality systems and enable their users to enjoy "a compelling VR experience". That approach, called "the I2I method", present 11 phases from "Establishing technological and competitive intelligence and industrial property" to "Improvements" through the "Definition of the Behavioral Interface, Virtual Environment and Behavioral Software Assistance". As a result of the experience gained by various research teams, this design approach benefits from contributions from current VR and AR research. Our objective is to validate and continuously move such multidisciplinary design team methods forward.

High-fiber rye diet increases ileal excretion of energy and macronutrients compared with low-fiber wheat diet independent of meal frequency in ileostomy subjects

PubMed Central

Isaksson, Hanna; Landberg, Rikard; Sundberg, Birgitta; Lundin, Eva; Hallmans, Göran; Zhang, Jie-Xian; Tidehag, Per; Erik Bach Knudsen, Knud; Moazzami, Ali A.; Åman, Per

2013-01-01

Background Whole-grain foods and cereal dietary fiber intake is associated with lower body weight. This may partly result from lower energy utilization of high-fiber diets. Objective In the present study, the impact on ileal excretion of energy and macronutrients in response to a rye bread high-fiber diet compared to a refined wheat low-fiber diet was investigated. Furthermore, the effect of meal frequency on apparent absorption of nutrients was studied for the first time. Design Ten participants that had undergone ileostomy consumed standardized iso-caloric diets, including low-fiber wheat bread (20 g dietary fiber per day) for 2 weeks followed by high-fiber rye bread (52 g dietary fiber per day) for 2 weeks. The diets were consumed in an ordinary (three meals per day) and a nibbling (seven meals per day) meal frequency in a cross-over design. Ileal effluents were collected during 24 h at the third day of each of the four dietary periods and analyzed for gross energy and nutrient contents. Results The results showed that intake of rye bread high-fiber diet compared to the refined wheat low-fiber diet caused an increase in ileal excretion of energy and macronutrients. The effect was independent of meal frequency. This suggests that a high intake of rye may result in lower availability of macronutrients for small intestinal digestion and absorption. A regular intake of rye may therefore have implications for weight management. PMID:24358035

Simultaneous determination of 11 designated hallucinogenic phenethylamines by ultra-fast liquid chromatography with fluorescence detection.

PubMed

Min, Jun Zhe; Shimizu, Yoshiha; Toyo'oka, Toshimasa; Inagaki, Shinsuke; Kikura-Hanajiri, Ruri; Goda, Yukihiro

2008-10-01

To avoid the spreading of illegal drugs, a designated drug regulation system was introduced along with revision of the Pharmaceutical Affairs Law in Japan in 2006, and 32 substances including phenethylamine-type drugs were listed in April 2007. In this study, a new simultaneous determination method, based on ultra-fast liquid chromatography coupled with fluorescence detection (UFLC-FL), was developed for the 11 designated phenethylamine drugs. The phenethylamines were labeled with 4-(N,N-dimethylaminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (DBD-F) at 60 degrees C for 2h in 0.1M borax (pH 9.3). The resulting 11 fluorophores were completely separated by reversed-phase chromatography using an ACQUITY UPLC BEH C(18) column (2.1 mm x 100 mm 1.7 microm) and fluorometrically detected at 550 nm (excitation at 450 nm). The calibration curves obtained from the peak areas versus the injection amounts of the phenethylamines showed a good linearity. The limits of detection (signal-to-noise ratio of 3: S/N=3) on the chromatogram were in the range from 10 fmol (PMMA) to 2.5pmol (MMDA-2). Good accuracy (%) and precision (CV) by intra-day assay and inter-day assay were also obtained using the present procedure. The method was applied to the qualitative and quantitative analyses of phenethylamine in real products obtained from the Japanese market. As the results, BDB (0.24 mg/mg), MMDA-2 (0.98 mg/mL) and 2C-I (0.016 mg/mg) were identified from the different products (powder, liquid and mushroom like). Because the procedure is simple, selective and sensitive, the present method seems to be useful for the qualitative and quantitative analyses of the designated phenethylamines in various samples including biological specimens.

The Effect of Hyperbaric Oxygen on the Growth of Mucor sp. Aspergillus fumigatus.

DTIC Science & Technology

1980-02-01

designations are for controls. 12 mamo 7<)U 4/ Figure 2. Aspergillus fumigatus Top Frame - Hyphae at day 2. Middle Frame - Plyphae with developing...conidiaphores, day 3. L~ower Frame - Hyphae with conidiophores and conidia, day 4. Time~ designations are for co~ntrols. 14 0 lOum Figure 3. Grouth curves

HX-POL - A Balloon-Bourne Hard X-Ray Polarimeter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krawczynski, H.; De Geronimo, G.; Garson, A., III, Martin, J.

2009-12-09

We report on the design and estimated performance of a balloon-borne hard X-ray polarimeter called HX-POL. The experiment uses a combination of Si and Cadmium Zinc Telluride detectors to measure the polarization of 50 keV-400 keV X-rays from cosmic sources through the dependence of the angular distribution of Compton scattered photons on the polarization direction. On a one-day balloon flight, HX-POL would allow us to measure the polarization of bright Crab-like sources for polarization degrees well below 10%. On a longer (15-30 day) flight from Australia or Antarctica, HX-POL would be be able to measure the polarization of bright galacticmore » X-ray sources down to polarization degrees of a few percent. Hard X-ray polarization measurements provide unique venues for the study of particle acceleration processes by compact objects and relativistic outflows. In this paper, we discuss the overall instrument design and performance. Furthermore, we present results from laboratory tests of the Si and CZT detectors.« less

Numerical Investigation of the Effect of Radial Lip Seal Geometry on Sealing Performance

NASA Astrophysics Data System (ADS)

Tok, G.; Parlar, Z.; Temiz, V.

2018-01-01

Sealing elements are often needed in industry and especially in machine design. With the change and development of machine technology from day to day, sealing elements show continuous development and change in parallel with these developments. Many factors influence the performance of the sealing elements such as shaft surface roughness, radial force, lip geometry etc. In addition, the radial lip seals must have a certain pre-load and interference in order to provide a good sealing. This also affects the friction torque. Researchers are developing new seal designs to reduce friction losses in mechanical systems. In the presented study, the effect of the lip seal geometry on sealing performance will be examined numerically. The numerical model created for this purpose will be verified with experimental data firstly. In the numerical model, shaft and seal will be modeled as hyper-elastic in 2D and 3D. NBR (Nitrile Butadiene Rubber) as seal material will be analyzed for the rotating shaft state at constant speed by applying a uniform radial force.

A fully implantable pacemaker for the mouse: from battery to wireless power.

PubMed

Laughner, Jacob I; Marrus, Scott B; Zellmer, Erik R; Weinheimer, Carla J; MacEwan, Matthew R; Cui, Sophia X; Nerbonne, Jeanne M; Efimov, Igor R

2013-01-01

Animal models have become a popular platform for the investigation of the molecular and systemic mechanisms of pathological cardiovascular physiology. Chronic pacing studies with implantable pacemakers in large animals have led to useful models of heart failure and atrial fibrillation. Unfortunately, molecular and genetic studies in these large animal models are often prohibitively expensive or not available. Conversely, the mouse is an excellent species for studying molecular mechanisms of cardiovascular disease through genetic engineering. However, the large size of available pacemakers does not lend itself to chronic pacing in mice. Here, we present the design for a novel, fully implantable wireless-powered pacemaker for mice capable of long-term (>30 days) pacing. This design is compared to a traditional battery-powered pacemaker to demonstrate critical advantages achieved through wireless inductive power transfer and control. Battery-powered and wireless-powered pacemakers were fabricated from standard electronic components in our laboratory. Mice (n = 24) were implanted with endocardial, battery-powered devices (n = 14) and epicardial, wireless-powered devices (n = 10). Wireless-powered devices were associated with reduced implant mortality and more reliable device function compared to battery-powered devices. Eight of 14 (57.1%) mice implanted with battery-powered pacemakers died following device implantation compared to 1 of 10 (10%) mice implanted with wireless-powered pacemakers. Moreover, device function was achieved for 30 days with the wireless-powered device compared to 6 days with the battery-powered device. The wireless-powered pacemaker system presented herein will allow electrophysiology studies in numerous genetically engineered mouse models as well as rapid pacing-induced heart failure and atrial arrhythmia in mice.

Onsite biological treatment of an industrial landfill leachate: Microbiological and engineering considerations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Skladany, G.J.

Successful biological treatment of ground waters, leachates, or industrial process waters requires the combined action of basic microbiological processes with sound process engineering designs. Such a treatment system is then able to both efficiently and cost-effectively remediate the contaminants present. In this case study, laboratory treatability studies were initially used to demonstrate that toluic acids present in an industrial landfill leachate were amenable to biological treatment. A continuous flow submerged fixed-film bioreactor was then chosen as the optimal equipment design for use at the site. The system was designed to treat a leachate flow of 800 to 2,000 gallons permore » day (gpd) containing total isomeric toluic acid concentrations of 300 to 400 parts per million (ppm). The treatment equipment has been in continuous operation since July 1987. During this period, the total influent isomertic toluic acid concentration has decreased to approximately 45 ppm, and specific effluent toluic acid concentrations have remained below the 0.5 ppm detection limit.« less

Field Demonstration of Real-Time Wind Turbine Foundation Strain Monitoring.

PubMed

Rubert, Tim; Perry, Marcus; Fusiek, Grzegorz; McAlorum, Jack; Niewczas, Pawel; Brotherston, Amanda; McCallum, David

2017-12-31

Onshore wind turbine foundations are generally over-engineered as their internal stress states are challenging to directly monitor during operation. While there are industry drivers to shift towards more economical foundation designs, making this transition safely will require new monitoring techniques, so that the uncertainties around structural health can be reduced. This paper presents the initial results of a real-time strain monitoring campaign for an operating wind turbine foundation. Selected reinforcement bars were instrumented with metal packaged optical fibre strain sensors prior to concrete casting. In this paper, we outline the sensors' design, characterisation and installation, and present 67 days of operational data. During this time, measured foundation strains did not exceed 95 μ ϵ , and showed a strong correlation with both measured tower displacements and the results of a foundation finite element model. The work demonstrates that real-time foundation monitoring is not only achievable, but that it has the potential to help operators and policymakers quantify the conservatism of their existing design codes.

Field Demonstration of Real-Time Wind Turbine Foundation Strain Monitoring

PubMed Central

Rubert, Tim; Niewczas, Pawel; Brotherston, Amanda; McCallum, David

2017-01-01

Onshore wind turbine foundations are generally over-engineered as their internal stress states are challenging to directly monitor during operation. While there are industry drivers to shift towards more economical foundation designs, making this transition safely will require new monitoring techniques, so that the uncertainties around structural health can be reduced. This paper presents the initial results of a real-time strain monitoring campaign for an operating wind turbine foundation. Selected reinforcement bars were instrumented with metal packaged optical fibre strain sensors prior to concrete casting. In this paper, we outline the sensors’ design, characterisation and installation, and present 67 days of operational data. During this time, measured foundation strains did not exceed 95 μϵ, and showed a strong correlation with both measured tower displacements and the results of a foundation finite element model. The work demonstrates that real-time foundation monitoring is not only achievable, but that it has the potential to help operators and policymakers quantify the conservatism of their existing design codes. PMID:29301232

Design of the Recovery Trajectory for JAXA Venus Orbiter Akatsuki

NASA Astrophysics Data System (ADS)

Campagnola, Stefano; Kawakatsu, Yasuhiro

2015-12-01

Akatsuki ("dawn" in Japanese) is the JAXA Venus orbiter that was scheduled to enter orbit around Venus on Dec. 7 th , 2010. Following the failure of the main engine during the orbit insertion maneuver, the spacecraft escaped Venus on a 200-day orbit around the Sun, only to return in early 2017. This paper presents the design and implementation of the recovery trajectory, which involves perihelion maneuvers to re-encounter Venus in late 2015. Relying only on the onboard propellant, the trajectory rescued the mission by (1) anticipating the beginning of the science phase within the nominal lifetime of the spacecraft, and (2) halving the Δ v requirements for the orbit insertion maneuver. Several trajectories are designed with an innovative use of a technique called non-tangent V-Infinity Leveraging Transfers (VILTs). Candidate solutions are then recomputed in higher fidelity models, and one solution is finally selected for its low Δv requirements and for programmatic reasons. The results of the perihelion maneuver campaign are also presented.

VLF Radio Wave Propagation Across the Day/Night Terminator

NASA Astrophysics Data System (ADS)

Burch, H.; Moore, R. C.

2016-12-01

In May 2016, a new array of VLF radio receivers was deployed spanning the East Coast of the United States. We present preliminary observations from the array, which was designed in part to track the propagation of the narrowband VLF transmitter signal, NAA (24.0 kHz), down the coast from Cutler, Maine. Amplitude, phase, and polarization observations are compared over multiple days and at different times of year to investigate the dependence of VLF propagation characteristics on solar zenith angle. Measurements are compared to simulations using the Long Wave Propagation Capability code (LWPC) in order to evaluate the accuracy of LWPC's built-in ionosphere model. Efforts to improve the ionosphere model based on observations are discussed.

Characterization of Microgravity Environment on Mir

NASA Technical Reports Server (NTRS)

Kim, Hyoung; Kaouk, Mohamed

2000-01-01

This paper presents the microgravity analysis results using dynamic response data collected during the first phase of the Mir Structural Dynamics Experiment (MiSDE). Although MiSDE was designed and performed to verify structural dynamic models, it also provided information for determining microgravity characteristics of the structure. This study analyzed ambient responses acquired during orbital day-to-night and night-to-day transitions, crew treadmill and ergometer exercises, and intentional crew activities. Acceleration levels for one-third octave bands were calculated to characterize the microgravity environment of the station. Spectrograms were also used to analyze the time transient nature of the responses. Detailed theoretical background and analysis results will also be included in the final draft.

30 CFR 715.18 - Dams constructed of or impounding waste material.

Code of Federal Regulations, 2011 CFR

2011-07-01

... existing or new dams without the approval of the regulatory authority. The permittee shall design, locate... design precipitation event within 10 days. (viii) During construction of dams subject to this section... adjacent to each dam within 30 days of certification of design pursuant to this section. (4) All dams...

Geospatial Engineering

DTIC Science & Technology

2017-02-22

manages operations through guidance, policies, programs, and organizations. The NSG is designed to be a mutually supportive enterprise that...deliberate technical design and deliberate human actions. Geospatial engineer teams (GETs) within the geospatial intelligence cells are the day-to-day...standards working group and are designated by the AGC Geospatial Acquisition Support Directorate as required for interoperability. Applicable standards

Development of Skylab environmental protection for photographic film

NASA Technical Reports Server (NTRS)

Askew, W. C.; Clarke, W. A.; Best, C. A.

1971-01-01

The problems of providing adequate environmental protection for photographic film on three Skylab missions and the technical and management approach to resolving these problems are presented. The radiation, temperature, and humidity environments to which film will be exposed for up to 230 days in space and the effects of these environments on film are discussed. The report concludes with a definition of the design requirements for the Skylab film repository.

The Role of the United States in a Changing World. A Curriculum Unit on Foreign Policy Choices.

ERIC Educational Resources Information Center

Brown Univ., Providence, RI. Center for Foreign Policy Development.

This 3- to 5-day currriculum unit for secondary students centers around four possible directions for U.S. foreign policy during the 1990s. Designed as a culminating exercise at the end of the year or as an introductory activity to open the semester, this unit, and the possible futures it presents, should be thought of as a vehicle for guiding…

Guantanamo Detention Facility - Why is it Still There

DTIC Science & Technology

2012-03-22

the detainees, dressed in orange jumpsuits, kneeling on the ground, being held in “ dog kennels ” - a perception that to this day is still seen by...President of the United States to use all necessary and appropriate force against those nations, organizations, or persons he determines planned ...incorporated in the design . Camp 5 is handicap accessible for detainees with physical disabilities.25 Legality of Detention Detainees presently being held

KENNEDY SPACE CENTER, FLA. - At Launch Complex 17-A, Cape Canaveral Air Force Station, a crane is in place to lift the fairing for the Mars Exploration Rover 2 (MER-2/MER-A). The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - At Launch Complex 17-A, Cape Canaveral Air Force Station, a crane is in place to lift the fairing for the Mars Exploration Rover 2 (MER-2/MER-A). The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

KENNEDY SPACE CENTER, FLA. - The fairing for the Mars Exploration Rover 2 (MER-2/MER-A) arrives at Launch Complex 17-A, Cape Canaveral Air Force Station. It will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - The fairing for the Mars Exploration Rover 2 (MER-2/MER-A) arrives at Launch Complex 17-A, Cape Canaveral Air Force Station. It will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

Sociocultural variables in youth access to tobacco: replication 5 years later.

PubMed

Landrine, H; Klonoff, E A; Campbell, R; Reina-Patton, A

2000-05-01

A prior study presented the only systematic investigation of the role of sociocultural variables in youth access to tobacco. White, black, and Latino girls and boys attempted to purchase cigarettes in the same 72 stores at the same time of day. Results revealed significantly greater sales to girls than to boys and to minorities than to whites. Before concluding that sociocultural variables must be addressed in merchant intervention programs designed to reduce youth access to tobacco, this study must be replicated, particularly in light of the significant decreases in youth access in the past 5 years. This article presents that replication. The stores used in the prior study were selected, and 12 white, black, and Latino girls and boys attempted to purchase cigarettes in those stores at the same time of day. Results Youths' access rate in 1999 (12.7%) was significantly lower than in the prior (1993-1995) study (41%). No effect for minors' gender was found, but the ethnicity effect again emerged: Black and Latino youth were 2.5 times more likely to be sold cigarettes than their white counterparts. Multiple sociocultural variables affect youth access to tobacco when access rates are high, but only youth ethnicity plays a role when access rates are low. Merchant interventions designed to reduce youth access to tobacco must address ethnic issues.

Addressing the leadership gap in medicine: residents' need for systematic leadership development training.

PubMed

Blumenthal, Daniel M; Bernard, Ken; Bohnen, Jordan; Bohmer, Richard

2012-04-01

All clinicians take on leadership responsibilities when delivering care. Evidence suggests that effective clinical leadership yields superior clinical outcomes. However, few residency programs systematically teach all residents how to lead, and many clinicians are inadequately prepared to meet their day-to-day clinical leadership responsibilities. The purpose of this article is twofold: first, to make the case for the need to refocus residency education around the development of outstanding "frontline" clinical leaders and, second, to provide an evidence-based framework for designing formal leadership development programs for residents. The authors first present a definition of clinical leadership and highlight evidence that effective frontline clinical leadership improves both clinical outcomes and satisfaction for patients and providers. The authors then discuss the health care "leadership gap" and describe barriers to implementing leadership development training in health care. Next, they present evidence that leaders are not just "born" but, rather, can be "made," and offer a set of best practices to facilitate the design of leadership development programs. Finally, the authors suggest approaches to mitigating barriers to implementing leadership development programs and highlight the major reasons why health care delivery organizations, residency programs, and national accreditation bodies must make comprehensive leadership education an explicit goal of residency training.

Effects of heat stress and probiotic supplementation on protein functionality and oxidative stability of ground chicken leg meat during display storage.

PubMed

Kim, Hyun-Wook; Kim, Ji-Han; Yan, Feifei; Cheng, Heng-Wei; Brad Kim, Yuan H

2017-12-01

The present study aimed to evaluate the effects of heat stress and probiotic supplementation on protein functionality and oxidative stability of ground chicken leg during display storage. Two hundred and forty, 1-day-old male chicks (5 birds per pen) were subjected to four treatments in a 2 (thermoneutral condition at 21 °C and cyclic heat stress at 32-21-32 °C for 10 h day -1 ) × 2 (regular diet with 0 or 0.25 g kg -1 Bacillus subtilis) factorial design. Chickens were harvested at day 46, and pairs of whole legs were collected at 1 day postmortem. The chicken legs were deboned, ground, tray-packaged with oxygen-permeable film, and displayed for 3 days. Heat stress and probiotic supplementation had no impact on pH, water-holding capacity, color, protein functionality, lipid lipolysis and lipid/protein oxidation stability (P > 0.05). Display storage increased the pH and lipid oxidation of ground chicken legs (P < 0.05). In addition, protein oxidation occurred during display storage, as determined via an increased carbonyl group (P = 0.0109) and reduced thiol group (P < 0.0001). The results of the present study indicate that chronic heat stress and probiotic supplementation had no practical adverse impact on protein functionality and oxidative stability of ground chicken leg meat. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Using present-day observations to detect when anthropogenic change forces surface ocean carbonate chemistry outside preindustrial bounds

NASA Astrophysics Data System (ADS)

Sutton, Adrienne J.; Sabine, Christopher L.; Feely, Richard A.; Cai, Wei-Jun; Cronin, Meghan F.; McPhaden, Michael J.; Morell, Julio M.; Newton, Jan A.; Noh, Jae-Hoon; Ólafsdóttir, Sólveig R.; Salisbury, Joseph E.; Send, Uwe; Vandemark, Douglas C.; Weller, Robert A.

2016-09-01

One of the major challenges to assessing the impact of ocean acidification on marine life is detecting and interpreting long-term change in the context of natural variability. This study addresses this need through a global synthesis of monthly pH and aragonite saturation state (Ωarag) climatologies for 12 open ocean, coastal, and coral reef locations using 3-hourly moored observations of surface seawater partial pressure of CO2 and pH collected together since as early as 2010. Mooring observations suggest open ocean subtropical and subarctic sites experience present-day surface pH and Ωarag conditions outside the bounds of preindustrial variability throughout most, if not all, of the year. In general, coastal mooring sites experience more natural variability and thus, more overlap with preindustrial conditions; however, present-day Ωarag conditions surpass biologically relevant thresholds associated with ocean acidification impacts on Mytilus californianus (Ωarag < 1.8) and Crassostrea gigas (Ωarag < 2.0) larvae in the California Current Ecosystem (CCE) and Mya arenaria larvae in the Gulf of Maine (Ωarag < 1.6). At the most variable mooring locations in coastal systems of the CCE, subseasonal conditions approached Ωarag = 1. Global and regional models and data syntheses of ship-based observations tended to underestimate seasonal variability compared to mooring observations. Efforts such as this to characterize all patterns of pH and Ωarag variability and change at key locations are fundamental to assessing present-day biological impacts of ocean acidification, further improving experimental design to interrogate organism response under real-world conditions, and improving predictive models and vulnerability assessments seeking to quantify the broader impacts of ocean acidification.

Effects of sodium lauryl sulphate (SLS), present in dentifrice, on volatile sulphur compound (VSC) formation in morning bad breath.

PubMed

Peruzzo, Daiane Cristina; Salvador, Sérgio Luis; Sallum, Antonio Wilson; da Nogueira-Filho, Getúlio Rocha

2008-10-01

The purpose of the present investigation was to evaluate the effects of sodium lauryl sulphate (SLS), present in a commercial dentifrice, on the formation of volatile sulphur compounds (VSC) and tongue coating in a panel of periodontally healthy subjects. A two-step blinded, crossover, randomized study was carried out in 25 dental students with healthy periodontium; these were divided into two experimental groups: SLS (dentifrice with SLS) and WSLS (dentifrice without SLS). The volunteers received the designated dentifrice and a new toothbrush for a 3x/day brushing regimen for 2 periods of 30 days. A seven-day washout interval was used between the periods. The assessed parameters were: plaque index (PI), gingival index (GI), organoleptic breath (ORG), VSC levels by portable sulphide monitor before (H1) and after (H2) cleaning of the tongue, tongue coating wet weight (TC) and benzoyl-DL-arginine-naphthylamide (BANA) test from tongue coating samples. The intra-group analysis showed a decrease in the median of organoleptic scores from 3 to 2 after 30 days for the SLS group (p < 0.05). The inter-group analysis showed lower values in ORG and H1 for the SLS group (p < 0.05). There was no difference between the amount of TC in SLS and WSLS groups. In the BANA test, the presence of SLS did not affect the BANA number of +/- results (p > 0.05). These findings suggest that sodium lauryl sulphate (SLS), present in dentifrice, appears to prevent VSC formation in morning bad breath regardless of the amount of tongue coating in periodontally healthy subjects.

Solar fed DC-DC single ended primary inductance converter for low power applications

NASA Astrophysics Data System (ADS)

Narendranath, K. V.; Viswanath, Y.; Babu, K. Suresh; Arunkumar, G.; Elangovan, D.

2017-11-01

This paper presents 34 to 36 volts. SEPIC converter for solar fed applications. Now days, there has been tremendous increase in the usage of solar energy and this solar energy is most valuable energy source available all around the world. The solar energy system require a Dc-Dc converter in order to modulate and govern the changing output of the panel. In this paper, a system comprising of Single Ended Primary Inductance Converter [SEPIC] integrated with solar panel is proposed. This paper proposes SEPIC power converter design that will secure high performance and cost efficiency while powering up a LAMP load. This power converter designed with low output ripple voltage, higher efficiency and less electrical pressure on the power switching elements. The simulation and prototype hardware results are presented in this paper.

Flight prototype CO2 and humidity control system

NASA Technical Reports Server (NTRS)

Rudy, K. M.

1977-01-01

A regenerable CO2 and humidity control system is presently being developed for potential use on the space shuttle as an alternative to the baseline lithium hydroxide system. The system utilizes a sorbent material (designated HS-C) to adsorb CO2 and water vapor from the cabin atmosphere and desorb the CO2 and water vapor overboard when exposed to a space vacuum. Continuous operation is achieved by utilizing two beds which are alternately cycled between adsorption and desorption. A shuttle vehicle integration study showed that the HS-C system offers substantial weight advantages compared to the baseline shuttle orbiter expendable lithium hydroxide CO2 removal system for extended missions beyond the nominal design of four men for seven days. This study defined a system packaging envelope in the area presently occupied by the LiOH cartridges.

Artificial heart for humanoid robot

NASA Astrophysics Data System (ADS)

Potnuru, Akshay; Wu, Lianjun; Tadesse, Yonas

2014-03-01

A soft robotic device inspired by the pumping action of a biological heart is presented in this study. Developing artificial heart to a humanoid robot enables us to make a better biomedical device for ultimate use in humans. As technology continues to become more advanced, the methods in which we implement high performance and biomimetic artificial organs is getting nearer each day. In this paper, we present the design and development of a soft artificial heart that can be used in a humanoid robot and simulate the functions of a human heart using shape memory alloy technology. The robotic heart is designed to pump a blood-like fluid to parts of the robot such as the face to simulate someone blushing or when someone is angry by the use of elastomeric substrates and certain features for the transport of fluids.

Test results of six-month test of two water electrolysis systems

NASA Technical Reports Server (NTRS)

Mills, E. S.; Wells, G. W.

1972-01-01

The two water electrolysis systems used in the NASA space station simulation 90-day manned test of a regenerative life support system were refurbished as required and subjected to 26-weeks of testing. The two electrolysis units are both promising systems for oxygen and hydrogen generation and both needed extensive long-term testing to evaluate the performance of the respective cell design and provide guidance for further development. Testing was conducted to evaluate performance in terms of current, pressure, variable oxygen demands, and orbital simulation. An automatic monitoring system was used to record, monitor and printout performance data at one minute, ten minute or one-hour intervals. Performance data is presented for each day of system operation for each module used during the day. Failures are analyzed, remedial action taken to eliminate problems is discussed and recommendations for redesign for future space applications are stated.

Durability of Anti-Infective Effect of Long-Term Silicone Sheath Catheters Impregnated with Antimicrobial Agents

PubMed Central

Tcholakian, Robert K.; Raad, Issam I.

2001-01-01

This study was performed to test the long-term antimicrobial efficacy of impregnated silicone catheters comprising an antimicrobial layer sandwiched between an external surface sheath and a luminal surface silicone sheath. The design of the catheter permits the introduction of various antimicrobials in addition to anticoagulants or antifibrins in the antimicrobial layer and allows their gradual release over a period of months after insertion. The in vitro data presented show that the catheter can provide antimicrobial activity for 90 days, after being replated for 15 7-day cycles of replating. When the catheters were immersed in human serum and incubated at 37°C, they demonstrated significant antimicrobial activity after more than 325 days of incubation. The significant long-term in vitro antimicrobial activity observed may imply effective in vivo activity for almost 1 year after insertion and could serve as a cost-effective alternative to surgically implantable silicone catheters. PMID:11408213

Semi-annual report of the Department of Energy Quality Assessment Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanderson, C.G.; Scarpitta, S.C.

1992-01-02

This report presents the results from the analysis of the 35th set of environmental quality assessment samples (QAP XXXV) that were received on or before December 5, 1991. This Quality Assessment Program (QAP) is designed to test the quality of the environmental measurements being reported to the Department of Energy by its contractors. Since 1976, real or synthetic environmental samples that have been prepared and thoroughly analyzed at the Environmental Measurements Laboratory (EML) have been distributed at first quarterly and then semi-annually to these contractors. Their results, which are returned to EML within 90 days, are compiled with EML`s resultsmore » and are reported back to the participating contractors 30 days later. A summary of the reported results is available to the participants 3 days after the reporting deadline via a modem-telephone connection to the EML computer.« less

Semi-annual report of the Department of Energy, Office of Environmental Restoration and Waste Management, Quality Assessment Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanderson, C.G.; Scarpitta, S.C.

1992-07-01

This report presents the results from the analysis of the 36th set of environmental quality assessment samples (QAP 36) that were received on or before January 2, 1992. This Quality Assessment Program (QAP) is designed to test the quality of the environmental measurements being reported to the Department of Energy by its contractors. Since 1976, real or synthetic environmental samples that have been prepared and thoroughly analyzed at the Environmental Measurements Laboratory (EML) have been distributed at first quarterly and then semi-annually to these contractors. Their results, which are returned to EML within 90 days, are complied with EML`s resultsmore » and are reported back to the participating contractors 30 days later. A summary of the reported results is available to the participants 3 days after the reporting deadline via a modem-telephone connection to the EML computer.« less

Semi-annual report of the Department of Energy, Office of Environmental Management, Quality Assessment Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanderson, C.G.; Greenlaw, P.

1996-02-01

This report presents the results from the analysis of the 43rd set of environmental quality assessment samples (QAP XLIII) that were received on or before December 1, 1995. This Quality Assessment Program (QAP) is designed to test the quality of the environmental measurements being reported to the Department of Energy by its contractors. Since 1976, real or synthetic environmental samples that have been prepared and thoroughly analyzed at the Environmental Measurements Laboratory (EML) have been distributed at first quarterly and then semi-annually to these contractors. Their results, which are returned to EML within 90 days, are compiled with EML`s resultsmore » and are reported back to the participating contractors 30 days later. A summary of the reported results is available to the participants 2 days after the reporting deadline via a modem-telephone connection to the EML computer.« less

Semi-annual report of the Department of Energy, Office of Environmental Management, Quality Assessment Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanderson, C.G.; Greenlaw, P.; Pan, V.

1995-07-03

This report presents the results from the analysis of the 42st set of environmental quality assessment samples (QAP XLII) that were received on or before June 1, 1995. This Quality Assessment Program (QAP) is designed to test the quality of the environmental measurements being reported to the Department of Energy by its contractors. Since 1976, real or synthetic environmental samples that have been prepared and thoroughly analyzed at the Environmental Measurements Laboratory (EML) have been distributed at first quarterly and then semi-annually to these contractors. Their results, which are returned to EML within 90 days, are compiled with EML`s resultsmore » and are reported back to the participating contractors 30 days later. A summary of the reported results is available to the participants 2 days after the reporting deadline via a modem-telephone connection to the EML computer.« less

Semi-annual report of the Department of Energy, Office of Environmental Management, Quality Assessment Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greenlaw, P.D.

1998-01-01

This Quality Assessment Program (QAP) is designed to test the quality of the environmental measurements being reported to the Department of Energy by its contractors. Since 1976, real or synthetic environmental samples that have been prepared and thoroughly analyzed at the Environmental Measurements Laboratory (EML) have been distributed at first quarterly and then semi-annually to these contractors. Their results, which are returned to EML within 90 days, are compiled with EML`s results and are reported back to the participating contractors 30 days later. A summary of the reported results is available to the participants 4 days after the reporting deadlinemore » via the Internet at www.eml.doe.gov. This report presents the results from the analysis of the 47th set of environmental quality assessment samples (QAP XLVII) that were received on or before December 1, 1997.« less

Semi-annual report of the Department of Energy, Office of Environmental Restoration and Waste Management, Quality Assessment Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanderson, C.G.; Klusek, C.S.

1993-07-01

This Quality Assessment Program (QAP) is designed to test the quality of the environmental measurements being reported to the Department of Energy by its contractors. Since 1976, real or synthetic environmental samples that have been prepared and thoroughly analyzed at the Environmental Measurements Laboratory (EML) have been distributed at first quarterly and then semi-annually to these contractors. Their results, which are returned to EML within 90 days, are compiled with EML`s results and are reported back to the participating contractors 30 days later. A summary of the reported results is available to the participants 3 days after the reporting deadlinemore » via a modem-telephone connection to the EML computer. This report presents the results from the analysis of the 38th set of environmental quality assessment samples (QAP XXXVIII) that were received on or before June 2, 1993.« less

Sickness absenteeism rate in Iranian schools during the 2009 epidemic of type a influenza.

PubMed

Pourabbasi, Ata; Shirvani, Mahbubeh Ebrahimnegad; Khashayar, Patricia

2012-02-01

Influenza pandemic was a global event in 2009 and intraschool transmission was its main spread method. The present study was designed to evaluate the absenteeism rate during the type A influenza epidemic. Four hundred and eight students from both a guidance school and high school in the Iranian capital were recruited in this retrospective study. The number of days of absenteeism, since the beginning of the school year until the end of the epidemic was recorded. Two hundred and thirteen students missed school during the disease epidemic because of related causes. In other words, 581 person day absences were reported during this period. The influenza pandemic has led to an increase in the absenteeism rate and may negatively affect the academic performance of the students. Teaching precautionary measures is an effective tool in reducing the number of days of sickness.

Standardisation of role players for the Clinical Skills Assessment of the MRCGP.

PubMed

Russell, David; Simpson, Robin; Rendel, Sue

2011-05-01

This paper describes the processes used to prepare the role players who simulate the 'patients' in the MRCGP Clinical Skills Assessment (CSA) examination, one of the licensing qualifications for GPs completing their training. Because it is such a high-stakes exam, the CSA must be seen to be fair and trustworthy, and such attributes could be compromised by inadequate role player performance. On a CSA examination day, three role players simulate the same 'patient' simultaneously on three different exam floors, each playing the same case up to 26 times on the day, and these 'patients' must present in a consistent and reliable manner to ensure that all candidates face the same test situation. The paper describes the initial selection and training of the actors, how they are prepared on the day of the exam itself, and the quality assurance processes designed to ensure that the exam has excellent role players performing as the simulated 'patients'.

Inherent uncertainties in meteorological parameters for wind turbine design

NASA Technical Reports Server (NTRS)

Doran, J. C.

1982-01-01

Major difficulties associated with meteorological measurments such as the inability to duplicate the experimental conditions from one day to the next are discussed. This lack of consistency is compounded by the stochastic nature of many of the meteorological variables of interest. Moreover, simple relationships derived in one location may be significantly altered by topographical or synoptic differences encountered at another. The effect of such factors is a degree of inherent uncertainty if an attempt is made to describe the atmosphere in terms of universal laws. Some of these uncertainties and their causes are examined, examples are presented and some implications for wind turbine design are suggested.

The 1973 GSFC battery workshop, second day. [technology transfer

NASA Technical Reports Server (NTRS)

1973-01-01

Technological progress in the development, testing, and manufacturing of nickel-cadmium battery cells as well as hydrogen cells is presented. The following major topics were discussed: (1) carbonate analysis; (2) nickel-cadmium memory effect; (3) use of batteries in an automatic acquisition and control system; (4) accelerated testing; (5) formulation of a mathematical odel for a nickel-cadmium cell; (6) development of a light weight nickel-cadmium battery capable of delivering 20 watt hours per pound; (7) magnetic testing of nickel-cadmium cells; (8) design and performance characteristics of nickel-hydrogen and silver-hydrogen cells; and (9) development of a semiprismatic cell design. For Vol. 1, see N75-15152.

Transfer Trajectory Design for the Mars Atmosphere and Volatile Evolution (MAVEN) Mission

NASA Technical Reports Server (NTRS)

Folta, David; Demcak, Stuart; Young, Brian; Berry, Kevin

2013-01-01

The Mars Atmosphere and Volatile Evolution (MAVEN) mission will determine the history of the loss of volatiles from the Martian atmosphere from a highly inclined elliptical orbit. MAVEN will launch from Cape Canaveral Air Force Station on an Atlas-V 401 during an extended 36-day launch period opening November 18, 2013. The MAVEN Navigation and Mission Design team performed a Monte Carlo analysis of the Type-II transfer to characterize; dispersions of the arrival B-Plane, trajectory correction maneuvers (TCMs), and the probability of Mars impact. This paper presents detailed analysis of critical MOI event coverage, maneuver constraints, deltaV-99 budgets, and Planetary Protection requirements.

Microstructured Surface Arrays for Injection of Zebrafish Larvae

PubMed Central

Irimia, Daniel

2017-01-01

Abstract Microinjection of zebrafish larvae is an essential technique for delivery of treatments, dyes, microbes, and xenotransplantation into various tissues. Although a number of casts are available to orient embryos at the single-cell stage, no device has been specifically designed to position hatching-stage larvae for microinjection of different tissues. In this study, we present a reusable silicone device consisting of arrayed microstructures, designed to immobilize 2 days postfertilization larvae in lateral, ventral, and dorsal orientations, while providing maximal access to target sites for microinjection. Injection of rhodamine dextran was used to demonstrate the utility of this device for precise microinjection of multiple anatomical targets. PMID:28151697

High Energy Cosmic Ray Electron Spectra measured from the ATIC Balloon Experiment

NASA Technical Reports Server (NTRS)

Chang, J.; Schmidt, W. K. H.; Adams, J. H.; Ahn, H. S.; Bashindzhagyan, G.; Batkov, K. E.; Christl, M.; Fazely, A. R.; Ganel, O.; Gunasingha, R. M.

2003-01-01

The Advanced Thin Ionization Calorimeter Balloon Experiment (ATIC) is specifically designed for high energy cosmic ray ion detection. From simulation and a CERN beam test exposure we find that the design consisting of a graphite target and an energy detection device, a totally active calorimeter of BGO scintillator, gives us sufficient information to distinguish electrons from protons up to the TeV energy range. Balloon observations were successfully carried out over Antarctica in both 2000/2001 and 2002/2003 for a total of more than 35 days. This paper presents preliminary results on the spectrum of high energy electrons observed in the first ATIC flight.

Initial results of the Global Thermospheric Mapping Study (GTMS)

NASA Technical Reports Server (NTRS)

Oliver, W. L.; Salah, J. E.; Musgrove, R. G.; Holt, J. M.; Wickwar, V. B.; Hernandez, G. J.; Roble, R. G.

1986-01-01

The Global Thermospheric Mapping Study (GTMS) is a multi-technique experimental study of the thermosphere designed to map simultaneously its spatial and temporal morphology with a thoroughness and diversity of measurement techniques heretofore unachieved. The GTMS is designed around the Incoherent Scatter Radar Chain in the western hemisphere. The European incoherent scatter radars and the worldwide communities of Fabry-Perot interferometers, meteor wind radars, partial reflection drifts radars, MST radars, and satellite probes are included to extend the spatial coverage and types of measurements available. Theoretical and modeling support in the areas of thermospheric and ionospheric structure, tides, and electric fields are included to aid in program planning and data interpretation. Solar activity was low on the three observation days (F10.7 = 97, 98, 96) and magnetic conditions were unsettled to active (A = 10, 12, 20). All six incoherent scatter radar facilities collected data. Each collected F region data day and night while Saint Santin and Millstone Hill additionally collected E region data during daylight hours. Initial results from Sondrestrom and Millstone Hill are presented. Good quality Fabry Perot data were collected at Fritz Peak and San Jose dos Campos. Weather conditions produced poor results at Arequipa and Arecibo. Initial results from Fritz Peak are presented. Mesosphere/lower-thermosphere observations were conducted under the ATMAP organization. The magnetometer chains also were operational during this campaign. Initial thermospheric general circulation model predictions were made for assumed solar-geophysical conditions, and selected results are presented.

Air pollution by particulate matter PM10 may trigger multiple sclerosis relapses.

PubMed

Roux, Jonathan; Bard, Denis; Le Pabic, Estelle; Segala, Claire; Reis, Jacques; Ongagna, Jean-Claude; de Sèze, Jérôme; Leray, Emmanuelle

2017-07-01

Seasonal variation of relapses in multiple sclerosis (MS) suggests that season-dependent factors, such as ambient air pollution, may trigger them. However, only few studies have considered possible role of air pollutants as relapse's risk factor. We investigated the effect of particulate matter of aerodynamic diameter smaller than 10µm (PM 10 ) on MS relapses. In total, 536 relapsing MS patients from Strasbourg city (France) were included, accounting for 2052 relapses over 2000-2009 period. A case-crossover design was used with cases defined as the days of relapse and controls being selected in the same patient at plus and minus 35 days. Different lags from 0 to 30 days were considered. Conditional logistic regressions, adjusted on meteorological parameters, school and public holidays, were used and exposure was considered first as a quantitative variable and second, as a binary variable. The natural logarithm of the average PM 10 concentration lagged from 1 to 3 days before relapse onset was significantly associated with relapse risk (OR =1.40 [95% confidence interval 1.08-1.81]) in cold season. Consistent results were observed when considering PM 10 as a binary variable, even if not significant. With an appropriate study design and robust ascertainment of neurological events and exposure, the present study highlights the effect of PM 10 on the risk of relapse in MS patients, probably through oxidative stress mechanisms. Copyright © 2017 Elsevier Inc. All rights reserved.

Exercise therapy and recovery after SCI: evidence that shows early intervention improves recovery of function

PubMed Central

Brown, AK; Woller, SA; Moreno, G; Grau, JW; Hook, MA

2011-01-01

Study design This was designed as an experimental study. Objectives Locomotor training is one of the most effective strategies currently available for facilitating recovery of function after an incomplete spinal cord injury (SCI). However, there is still controversy regarding the timing of treatment initiation for maximal recovery benefits. To address this issue, the present study compares the effects of exercise initiated in the acute and secondary phase of SCI. Setting Texas A&M University, College Station, TX, USA. Methods Rats received a moderate spinal contusion injury and began an exercise program 1 (D1-EX) or 8 days (D8-EX) later. They were individually placed into transparent exercise balls for 60 min per day, for 14 consecutive days. Control rats were placed in exercise balls that were rendered immobile. Motor and sensory recovery was assessed for 28 days after injury. Results The D1-EX rats recovered significantly more locomotor function (BBB scale) than controls and D8-EX rats. Moreover, analyses revealed that rats in the D8-EX group had significantly lower tactile reactivity thresholds compared with control and D1-EX rats, and symptoms of allodynia were not reversed by exercise. Rats in the D8-EX group also had significantly larger areas of damage across spinal sections caudal to the injury center compared with the D1-EX group. Conclusion These results indicate that implementing an exercise regimen in the acute phase of SCI maximizes the potential for recovery of function. PMID:21242998

Blood and tissue fatty acid compositions, lipoprotein levels, performance and meat flavor of broilers fed fish oil: changes in the pre- and post-withdrawal design.

PubMed

Aghaei, N; Safamehr, A; Mehmannavaz, Y; Chekaniazar, S

2012-12-01

Administration of fish oil (FO) in broiler diets can elevate α-linolenic acid (ALA), eicosapentanoic acid (EPA) and docosahexanoic acid (DHA) levels, which are protective against cardiovascular disease. However, optimization based solely on n-3 polyunsaturated fatty acid (n-3 PUFA) enrichment in chicken meat could lead to lower meat quality, unless the withdrawal period (plan) is applied for 1 week. The present study investigated whether the incorporation of FO in the diet for 32 days followed by its withdrawal for 1 week affected blood lipid profiles, lipoprotein particles, performance and meat flavor in male broiler chickens. Two hundred and forty birds (1-day-old, Ross 308) were assigned to 1 of 4 dietary groups: 0%, 1%, 2% or 3% FO with four replicates. Broilers were fed for 49 days according to a 4-phase feeding program. The experimental phase comprised day 11 to 42, and FO was removed on day 42. Blood samples were collected during the pre- and post-withdrawal period after the recordings before slaughter. The FO groups demonstrated decreased low-density lipoprotein (LDL) and increased high-density lipoprotein levels on day 42 (P < 0.01); however, these values were not significant after design withdrawal. Diet supplementation with FO elevated the blood levels of palmitic acid (C16:0) and n-3 PUFAs, especially long-chain (LC) PUFAs (EPA, C20:5n-3 and DHA, C22:6n-3), and caused a decline in the level of arachidonic acid (AA, C20:4n-6; P < 0.05). Application of a one-week withdrawal period resulted in a decrease in (P < 0.05) linoleic acid (C18:2n-6) and an increase in the level of AA, unlike their amounts on day 42. Although blood and tissue LC n-3 PUFA levels on day 49 were significantly higher in the FO groups compared with the control, they demonstrated a substantial decrease on day 49 compared with day 42. The best results, mainly the lowest n-6/n-3 fatty acids (FAs) and feed conversion ratio (FCRs), were observed for 3% FO (group T4), even after institution of the withdrawal design. Degradation of total n-3 FAs deposited in tissues occurred after instituting the withdrawal plan diet, but deposited levels of EPA and DHA in tissues could ensure omega-3 enrichment of broiler meat in groups 3 and 4. On the basis of the dissatisfaction of the panelists toward group 4 meats (scored as near to acceptable) and their satisfaction with cooked samples of T3 (scored as good), group 3 meats were selected as good-quality n-3-enriched broiler meat.

A spatially augmented reality sketching interface for architectural daylighting design.

PubMed

Sheng, Yu; Yapo, Theodore C; Young, Christopher; Cutler, Barbara

2011-01-01

We present an application of interactive global illumination and spatially augmented reality to architectural daylight modeling that allows designers to explore alternative designs and new technologies for improving the sustainability of their buildings. Images of a model in the real world, captured by a camera above the scene, are processed to construct a virtual 3D model. To achieve interactive rendering rates, we use a hybrid rendering technique, leveraging radiosity to simulate the interreflectance between diffuse patches and shadow volumes to generate per-pixel direct illumination. The rendered images are then projected on the real model by four calibrated projectors to help users study the daylighting illumination. The virtual heliodon is a physical design environment in which multiple designers, a designer and a client, or a teacher and students can gather to experience animated visualizations of the natural illumination within a proposed design by controlling the time of day, season, and climate. Furthermore, participants may interactively redesign the geometry and materials of the space by manipulating physical design elements and see the updated lighting simulation. © 2011 IEEE Published by the IEEE Computer Society

Effects of Task-oriented Approach on Affected Arm Function in Children with Spastic Hemiplegia Due to Cerebral Palsy.

PubMed

Song, Chiang-Soon

2014-06-01

[Purpose] The purpose of the present study was to examine the effects of task-oriented approach on motor function of the affected arm in children with spastic hemiplegia due to cerebral palsy. [Subjects] Twelve children were recruited by convenience sampling from 2 local rehabilitation centers. The present study utilized a one-group pretest-posttest design. All of children received task-oriented training for 6 weeks (40 min/day, 5 days/week) and also underwent regular occupational therapy. Three clinical tests, Box and Block Test (BBT), Manual Ability Measure (MAM-16), and Wee Functional Independence Measure (WeeFIM) were performed 1 day before and after training to evaluate the effects of the training. [Results] Compared with the pretest scores, there was a significant increase in the BBT, MAM-16, and WeeFIM scores of the children after the 6-week practice period. [Conclusion] The results of this study suggest that a task-oriented approach to treatment of the affected arm improves functional activities, such as manual dexterity and fine motor performance, as well as basic daily activities of patients with spastic hemiplegia due to cerebral palsy.

Measuring happiness in individuals with profound multiple disabilities.

PubMed

Darling, Joseph A; Circo, Deborah K

2015-12-01

This quantitative study assessed whether presentation of preferred items and activities during multiple periods of the day (and over multiple days) increased indices of happiness (over time/sustained) in individuals with PMD. A multiple baseline design across participants was utilized to measure changes in indices of happiness of the participants. Participants were recruited from an adult day activity program specializing in providing assistance to individuals with disabilities. For Mary, baseline indices of happiness were 26.67% of intervals, increasing 6.76% during intervention to 33.43%. For Caleb, baseline indices of happiness were 20.84% of intervals, increasing 6.34% during intervention to 27.18%. For Mark, baseline indices of happiness were 40.00% of intervals, increasing 12.75% during intervention to 52.75%. Overall interobserver agreement was 82.8%, with interobserver agreement observations occurring during 63.04% of the observations. The results of the investigation demonstrated that presenting preferred items and activities increased the indices of happiness compared to baseline rates of indices of happiness. Results may have been more robust if the participants were assessed for overall responsiveness patterns prior to the initiation of measurement of indices of happiness. Copyright © 2015 Elsevier Ltd. All rights reserved.

Design and optimization of smart grid system based on renewable energy in Nyamuk Island, Karimunjawa district, Central Java

NASA Astrophysics Data System (ADS)

Novitasari, D.; Indartono, Y. S.; Rachmidha, T. D.; Reksowardojo, I. K.; Irsyad, M.

2017-03-01

Nyamuk Island in Karimunjawa District is one of the regions in Java that has no access to electricity grid. The electricity in Nyamuk Island relies on diesel engine which is managed by local government and only operated for 6 hours per day. It occurs as a consequence of high fuel cost. A study on smart micro grid system based on renewable energy was conducted in Combustion Engine and Propulsion System Laboratory of Institut Teknologi Bandung by using 1 kWp solar panels and a 3 kW bio based diesel engine. The fuels used to run the bio based diesel engine were diesel, virgin coconut oil and pure palm oil. The results show that the smart grid system run well at varying load and also with different fuel. Based on the experiments, average inverter efficiency was about 87%. This experiments proved that the use of biofuels had no effects to the overall system performance. Based on the results of prototype experiments, this paper will focus on design and optimization of smart micro grid system using HOMER software for Nyamuk Island. The design consists of (1) a diesel engine existing in Nyamuk Island whose fuel was diesel, (2) a lister engine whose fuel was from vegetable oil from Callophyllum inophyllum, (3) solar panels, (4) batteries and (5) converter. In this simulation, the existing diesel engine was set to operate 2 hours per day, while operating time of the lister engine has been varied with several scenarios. In scenario I, the lister engine was operated 5 hours per day, in scenario II the lister engine was operated 24 hours per day and in scenario III the lister engine was operated 8 hours per week in the weekend. In addition, a design using a modified diesel engine was conducted as well with an assumption that the modified cost was about 10% of new diesel engine cost. By modifying the diesel engine, the system will not need a lister engine. Assessments has been done to evaluate the designs, and the result shows that the optimal value obtains by the lister engine being operated for 24 hours a day in which the capacity of each component was 27 kWp PV, 7 kW lister engine, 26 kVA existing diesel engine, 40 kW converter and 128 batteries. The result is based on the lowest value of Net Present Cost (NPC) of 542.682 and Cost Of Electricity (COE) of 0.49.

Sentinel-3 coverage-driven mission design: Coupling of orbit selection and instrument design

NASA Astrophysics Data System (ADS)

Cornara, S.; Pirondini, F.; Palmade, J. L.

2017-11-01

The first satellite of the Sentinel-3 series was launched in February 2016. Sentinel-3 payload suite encompasses the Ocean and Land Colour Instrument (OLCI) with a swath of 1270 km, the Sea and Land Surface Temperature Radiometer (SLSTR) yielding a dual-view scan with swaths of 1420 km (nadir) and 750 km (oblique view), the Synthetic Aperture Radar Altimeter (SRAL) working in Ku-band and C-band, and the dual-frequency Microwave Radiometer (MWR). In the early stages of mission and system design, the main driver for the Sentinel-3 reference orbit selection was the requirement to achieve a revisit time of two days or less globally over ocean areas with two satellites (i.e. 4-day global coverage with one satellite). The orbit selection was seamlessly coupled with the OLCI instrument design in terms of field of view (FoV) definition driven by the observation zenith angle (OZA) and sunglint constraints applied to ocean observations. The criticality of the global coverage requirement for ocean monitoring derives from the sunglint phenomenon, i.e. the impact on visible channels of the solar ray reflection on the water surface. This constraint was finally overcome thanks to the concurrent optimisation of the orbit parameters, notably the Local Time at Descending Node (LTDN), and the OLCI instrument FoV definition. The orbit selection process started with the identification of orbits with short repeat cycle (2-4 days), firstly to minimise the time required to achieve global coverage with existing constraints, and then to minimise the swath required to obtain global coverage and the maximum required OZA. This step yielded the selection of a 4-day repeat cycle orbit, thus allowing 2-day coverage with two adequately spaced satellites. Then suitable candidate orbits with higher repeat cycles were identified in the proximity of the selected altitudes and the reference orbit was ultimately chosen. Rationale was to keep the swath for global coverage as close as possible to the previous optimum value, but to tailor the repeat cycle length (i.e. the ground-track grid) to optimise the topography mission performances. The final choice converged on the sun-synchronous orbit 14 + 7/27, reference altitude ∼800 km, LTDN = 10h00. Extensive coverage analyses were carried out to characterise the mission performance and the fulfilment of the requirements, encompassing revisit time, number of acquisitions, observation viewing geometry and swath properties. This paper presents a comprehensive overview of the Sentinel-3 orbit selection, starting from coverage requirements and highlighting the close interaction with the instrument design activity.

Research on the exploitation of advanced composite materials to lightly loaded structures

NASA Technical Reports Server (NTRS)

Mar, J. W.

1976-01-01

The objective was to create a sailplane which could fly in weaker thermals than present day sailplanes (by being lighter) and to fly in stronger thermals than present sailplanes (by carrying more water ballast). The research was to tackle the interaction of advanced composites and the aerodynamic performance, the interaction of fabrication procedures and the advanced composites, and the interaction of advanced composites and the design process. Many pieces of the overall system were investigated but none were carried to the resolution required for engineering application. Nonetheless, interesting and useful results were obtained and are here reported.

High-Speed Research: Sonic Boom, volume 2

NASA Technical Reports Server (NTRS)

Darden, Christine M. (Compiler)

1992-01-01

A High-Speed Sonic Boom Workshop was held at NASA Langley Research Center on February 25-27, 1992. The purpose of the workshop was to make presentations on current research activities and accomplishments and to assess progress in the area of sonic boom since the program was initiated in FY-90. Twenty-nine papers were presented during the 2-1/2 day workshop. Attendees included representatives from academia, industry, and government who are actively involved in sonic-boom research. Volume 2 contains papers related to low sonic-boom design and analysis using both linear theory and higher order computational fluid dynamics (CFD) methods.

Helium refrigeration considerations for cryomodule design

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ganni, V.; Knudsen, P.

Many of the present day accelerators are based on superconducting radio frequency (SRF) cavities, packaged in cryo-modules (CM), which depend on helium refrigeration at sub-atmospheric pressures, nominally 2 K. These specialized helium refrigeration systems are quite cost intensive to produce and operate. Particularly as there is typically no work extraction below the 4.5-K supply, it is important that the exergy loss between this temperature level and the CM load temperature(s) be minimized by the process configuration choices. This paper will present, compare and discuss several possible helium distribution process arrangements to support the CM loads.

The Scintillating Optical Fiber Calorimeter Instrument Performance (SOFCAL)

NASA Technical Reports Server (NTRS)

Christl, M. J.; Benson, C. M.; Berry, F. A.; Fountain, W. F.; Gregory, J. C.; Johnson, J. S.; Munroe, R. B.; Parnell, T. A.; Takahashi, Y.; Watts, J. W.

1999-01-01

SOFCAL is a balloon-borne instrument designed to measure the P-He cosmic ray spectra from about 200 GeV/amu - 20 TeV/amu. SOFCAL uses a thin lead and scintillating-fiber ionization calorimeter to measure the cascades produced by cosmic rays interacting in the hybrid detector system. Above the fiber calorimeter is an emulsion chamber that provides the interaction target, primary particle identification and in-flight energy calibration for the scintillating fiber data. The energy measurement technique and its calibration are described, and the present results from the analysis of a 1 day balloon flight will be presented.

DOE Coal Gasification Multi-Test Facility: fossil fuel processing technical/professional services

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hefferan, J.K.; Lee, G.Y.; Boesch, L.P.

1979-07-13

A conceptual design, including process descriptions, heat and material balances, process flow diagrams, utility requirements, schedule, capital and operating cost estimate, and alternative design considerations, is presented for the DOE Coal Gasification Multi-Test Facility (GMTF). The GMTF, an engineering scale facility, is to provide a complete plant into which different types of gasifiers and conversion/synthesis equipment can be readily integrated for testing in an operational environment at relatively low cost. The design allows for operation of several gasifiers simultaneously at a total coal throughput of 2500 tons/day; individual gasifiers operate at up to 1200 tons/day and 600 psig using airmore » or oxygen. Ten different test gasifiers can be in place at the facility, but only three can be operated at one time. The GMTF can produce a spectrum of saleable products, including low Btu, synthesis and pipeline gases, hydrogen (for fuel cells or hydrogasification), methanol, gasoline, diesel and fuel oils, organic chemicals, and electrical power (potentially). In 1979 dollars, the base facility requires a $288 million capital investment for common-use units, $193 million for four gasification units and four synthesis units, and $305 million for six years of operation. Critical reviews of detailed vendor designs are appended for a methanol synthesis unit, three entrained flow gasifiers, a fluidized bed gasifier, and a hydrogasifier/slag-bath gasifier.« less

Adult Day Care

MedlinePlus

... Page Resize Text Printer Friendly Online Chat Adult Day Care Adult Day Care Centers are designed to provide care and ... adults who need assistance or supervision during the day. Programs offer relief to family members and caregivers, ...

Experiences of attending day care services designed for people with dementia - a qualitative study with individual interviews.

PubMed

Strandenæs, Margit Gausdal; Lund, Anne; Rokstad, Anne Marie Mork

2018-06-01

Day care is assumed to promote independence in home-dwelling people with dementia, increase well-being and enhance social stimulation. Few studies have directly engaged people with dementia to better understand the benefits and impacts of such services. The aim of this study was to explore attendees' experiences with day care designed for people with dementia. This study had a qualitative descriptive design and included individual interviews with 17 users attending day care. The analysis was undertaken using content analyses. The participants reported that day care had a positive influence on their physical functioning, cognition, well-being, and situation at home because they were provided with social stimulation, meals, and activities. Day care contributed to the maintenance of a rhythm and structure in everyday life. Furthermore, the staff contributed to making the day care a safe place to be and enhanced a sense of belonging. This study reveals the positive impact of day care on the daily lives of people with dementia because this service contributes to the enhancement of activities and social support, prevents isolation, and enhances practical and cognitive functioning as experienced by the users. The staff has a major impact on the experience of the participants in the day care.

High temperature superconducting infrared imaging satellite

NASA Technical Reports Server (NTRS)

Angus, B.; Covelli, J.; Davinic, N.; Hailey, J.; Jones, E.; Ortiz, V.; Racine, J.; Satterwhite, D.; Spriesterbach, T.; Sorensen, D.

1992-01-01

A low earth orbiting platform for an infrared (IR) sensor payload is examined based on the requirements of a Naval Research Laboratory statement of work. The experiment payload is a 1.5-meter square by 0.5-meter high cubic structure equipped with the imaging system, radiators, and spacecraft mounting interface. The orbit is circular at 509 km (275 nmi) altitude and 70 deg. inclination. The spacecraft is three-axis stabilized with pointing accuracy of plus or minus 0.5 deg. in each axis. The experiment payload requires two 15-minute sensing periods over two contiguous orbit periods for 30 minutes of sensing time per day. The spacecraft design is presented for launch via a Delta 2 rocket. Subsystem designs include attitude control, propulsion, electric power, telemetry, tracking and command, thermal design, structure, and cost analysis.

Thermal performance assessment of a large aperture concentrating collector in an industrial application in Chile

NASA Astrophysics Data System (ADS)

Murray, Clare; Pino, Alan; Cardemil, José Miguel; Escobar, Rodrigo

2017-06-01

The application of solar thermal energy to meet the heat demands of the food and beverage processing industry in Chile has huge potential. This paper presents an assessment of the first large aperture trough collector installed in Latin America. The collector preheats water for a boiler in a juice-concentrating factory, 100 km north of Santiago. An analysis of the system for a day in November indicates the system was not able to utilize the heat generated, resulting in rapid de- and refocusing of the collector and problems with sensor calibration. An analysis of a day in March indicates the tracking algorithm has not correctly aligned the collector with the sun's position. An investigation into the design document reveals that the meteorological data underestimates the actual irradiation values by 40%, resulting in an oversized system given the actual conditions. To increase the energy gain in the system it is proposed to increase the working pressure from the current value of 1.5bar to up to 5bar, which could increase the system utilization from 41% to 65% and reduce the dumped energy to near zero. The simulation results with actual weather data and a fixed inlet temperature indicate the annual solar fraction could increase from the design value of 8.1% to 31.8% with a working pressure of 5 bar. The plant presents multiple opportunities for improvement not only to the performance of the plant but also in the design and installation of solar thermal systems in Chile in the future.

Coronagraph particulate measurements. Skylab flight experiment T025

NASA Technical Reports Server (NTRS)

Greenberg, J. M.; Schuerman, D. W.; Giovane, F.; Wang, R. T.; Hardy, D. C.

1975-01-01

Major results of the Skylab T025 Coronagraph experiment designed to monitor the particulate contamination about the spacecraft and to study the earth's atmospheric aerosol distribution are presented. A model for comet outbursts based on the properties of amorphous ice and ground based narrow-band and white light photography of comet Kohoutek ten days to perihelion are included. The effect of atmospheric refraction on the analysis of the T025 atmospheric data was also investigated.

Information Resources Management: Systems Communicating with Systems. A Session Especially Designed by Senior Managers for Senior Management Officials. Viewgraphs and Presentations. Intensive One-Day Symposium (Gaithersburg, Maryland, December 3, 1987).

ERIC Educational Resources Information Center

General Services Administration, Washington, DC.

Summaries of the welcoming and opening remarks for a symposium on the standards issues that will affect the federal government's planning, acquisition, and use of integrated computer and telecommunications systems over the next five years set the stage for the keynote address by Joseph Timko of IBM entitled "Standards--Perspectives and Evolution."…

[Environmental dependencies, architecture and psychiatry: is the asylum back?].

PubMed

Severo, Donato

2012-01-01

From the time of the asylum as an "instrument of healing" to the present day, history has shown the importance of architecture in the design and organisation of psychiatric care. It manifests itself in many different ways, from the organisation of the therapeutic area, the typologies of the care facilities, to the relationship with the town, the area and nature. There is a close link between the care facility and the town.

A Bold Goal: More Healthy Days Through Improved Community Health.

PubMed

Cordier, Tristan; Song, Yongjia; Cambon, Jesse; Haugh, Gil S; Steffen, Mark; Hardy, Patty; Staehly, Marnie; Hagan, Angela; Gopal, Vipin; Tye, Pattie Dale; Renda, Andrew

2017-11-10

Humana, a large health care company, has set a goal of 20% improvement in health in the communities it serves by 2020. The metric chosen for the Bold Goal initiative was the HRQOL-4 version of the Centers for Disease Control and Prevention (CDC) Healthy Days survey. This paper presents the methods for measuring progress, reports results for the first year of tracking, and describes Humana's community-based interventions. Across 7 specially designated "Bold Goal" communities, mean unhealthy days declined from 10.98 in 2015 to 10.64 in 2016, which represented a 3.1% relative, or 0.34 absolute, decline. This compares with a 0.17 absolute unhealthy days decline in Humana's national population overall. The paper also describes how additional work identifying associations between social determinants of health (SDOH) and Healthy Days is influencing Humana's strategy. Lastly, a strategy of community engagement is illustrated through 2 case examples: San Antonio and Knoxville. In the San Antonio area, the community in which Humana has been involved the longest, unhealthy days dropped by 9.0% (-0.95 absolute) from a mean 10.52 to 9.57 unhealthy days. In Knoxville, one of the newer areas of engagement, mean unhealthy days declined by 4.8% (-0.61 absolute), representing declines in both physically and mentally unhealthy days. Overall, results are encouraging, and Humana expects declines to accelerate over time as initiatives are launched and scaled in Bold Goal communities.

A Bold Goal: More Healthy Days Through Improved Community Health

PubMed Central

Cordier, Tristan; Song, Yongjia; Cambon, Jesse; Haugh, Gil S.; Steffen, Mark; Hardy, Patty; Staehly, Marnie; Hagan, Angela; Gopal, Vipin; Tye, Pattie Dale

2018-01-01

Abstract Humana, a large health care company, has set a goal of 20% improvement in health in the communities it serves by 2020. The metric chosen for the Bold Goal initiative was the HRQOL-4 version of the Centers for Disease Control and Prevention (CDC) Healthy Days survey. This paper presents the methods for measuring progress, reports results for the first year of tracking, and describes Humana's community-based interventions. Across 7 specially designated “Bold Goal” communities, mean unhealthy days declined from 10.98 in 2015 to 10.64 in 2016, which represented a 3.1% relative, or 0.34 absolute, decline. This compares with a 0.17 absolute unhealthy days decline in Humana's national population overall. The paper also describes how additional work identifying associations between social determinants of health (SDOH) and Healthy Days is influencing Humana's strategy. Lastly, a strategy of community engagement is illustrated through 2 case examples: San Antonio and Knoxville. In the San Antonio area, the community in which Humana has been involved the longest, unhealthy days dropped by 9.0% (−0.95 absolute) from a mean 10.52 to 9.57 unhealthy days. In Knoxville, one of the newer areas of engagement, mean unhealthy days declined by 4.8% (−0.61 absolute), representing declines in both physically and mentally unhealthy days. Overall, results are encouraging, and Humana expects declines to accelerate over time as initiatives are launched and scaled in Bold Goal communities. PMID:29125796

Straylight analysis of the BepiColombo Laser Altimeter

NASA Astrophysics Data System (ADS)

Weigel, T.; Rugi-Grond, E.; Kudielka, K.

2008-09-01

The BepiColombo Laser Altimeter (BELA) shall profile the surface of planet Mercury and operates on the day side as well as on the night side. Because of the high thermal loads, most interior surfaces of the front optics are highly reflective and specular, including the baffle. This puts a handicap on the straylight performance, which is needed to limit the solar background. We present the design measures used to reach an attenuation of about 10-8. We resume the method of backward straylight analysis which starts the rays at the detector and analyses the results in object space. The backward analysis can be quickly compiled and challenges computer resources rather than labor effort. This is very useful in a conceptual design phase when a design is iterated and trade-offs are to be performed. For one design, we compare the results with values obtained from a forward analysis.

Aerodynamic design of electric and hybrid vehicles: A guidebook

NASA Technical Reports Server (NTRS)

Kurtz, D. W.

1980-01-01

A typical present-day subcompact electric hybrid vehicle (EHV), operating on an SAE J227a D driving cycle, consumes up to 35% of its road energy requirement overcoming aerodynamic resistance. The application of an integrated system design approach, where drag reduction is an important design parameter, can increase the cycle range by more than 15%. This guidebook highlights a logic strategy for including aerodynamic drag reduction in the design of electric and hybrid vehicles to the degree appropriate to the mission requirements. Backup information and procedures are included in order to implement the strategy. Elements of the procedure are based on extensive wind tunnel tests involving generic subscale models and full-scale prototype EHVs. The user need not have any previous aerodynamic background. By necessity, the procedure utilizes many generic approximations and assumptions resulting in various levels of uncertainty. Dealing with these uncertainties, however, is a key feature of the strategy.

Human Mars Ascent Vehicle Configuration and Performance Sensitivities

NASA Technical Reports Server (NTRS)

Polsgrove, Tara P.; Thomas, Herbert D.; Stephens, Walter; Collins, Tim; Rucker, Michelle; Gernhardt, Mike; Zwack, Matthew R.; Dees, Patrick D.

2017-01-01

The total ascent vehicle mass drives performance requirements for the Mars descent systems and the Earth to Mars transportation elements. Minimizing Mars Ascent Vehicle (MAV) mass is a priority and minimizing the crew cabin size and mass is one way to do that. Human missions to Mars may utilize several small cabins where crew members could live for days up to a couple of weeks. A common crew cabin design that can perform in each of these applications is desired and could reduce the overall mission cost. However, for the MAV, the crew cabin size and mass can have a large impact on vehicle design and performance. This paper explores the sensitivities to trajectory, propulsion, crew cabin size and the benefits and impacts of using a common crew cabin design for the MAV. Results of these trades will be presented along with mass and performance estimates for the selected design.

Critical Perspectives of Technology-Enhanced Learning in Relation to Specialist Communication Design Studio Education within the UK and Australia

ERIC Educational Resources Information Center

Marshalsey, Lorraine; Sclater, Madeleine

2018-01-01

This paper investigates the widespread integration of technology-enhanced learning (TEL) within specialist Communication Design studio education in the UK and Australia. The impetus for this paper has grown from the challenges facing day-to-day design studio education and the recognition that the use of technology in higher education today has…

A Pilot Sampling Design for Estimating Outdoor Recreation Site Visits on the National Forests

Treesearch

Stanley J. Zarnoch; S.M. Kocis; H. Ken Cordell; D.B.K. English

2002-01-01

A pilot sampling design is described for estimating site visits to National Forest System lands. The three-stage sampling design consisted of national forest ranger districts, site days within ranger districts, and last-exiting recreation visitors within site days. Stratification was used at both the primary and secondary stages. Ranger districts were stratified based...

A Summary of Proceedings for the Advanced Deployable Day/Night Simulation Symposium

DTIC Science & Technology

2009-07-01

initiated to design , develop, and deliver transportable visual simulations that jointly provide night-vision and high-resolution daylight capability. The...Deployable Day/Night Simulation (ADDNS) Technology Demonstration Project was initiated to design , develop, and deliver transportable visual...was Dr. Richard Wildes (York University); Mr. Vitaly Zholudev (Department of Computer Science, York University), Mr. X. Zhu (Neptec Design Group), and

78 FR 70949 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-27

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for...). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the HHS decision to designate a..., 1967, for a number of work days aggregating at least 250 work days, occurring either solely under this...

77 FR 60437 - Final Effect of Designation of a Class of Employees for Addition to the Special Exposure Cohort

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-03

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Final Effect of Designation of a Class of Employees for...). ACTION: Notice. SUMMARY: HHS gives notice concerning the final effect of the HHS decision to designate a... August 1, 1949, through December 31, 1967, for a number of work days aggregating at least 250 work days...

Carotid artery stenting in high surgical risk patients using the FiberNet embolic protection system: the EPIC trial results.

PubMed

Myla, Subbarao; Bacharach, J Michael; Ansel, Gary M; Dippel, Eric J; McCormick, Daniel J; Popma, Jeffrey J

2010-05-01

The multicenter EPIC (FiberNet Embolic Protection System in Carotid Artery Stenting Trial) single-arm trial evaluated the 30-day outcomes of a new design concept for embolic protection during carotid artery stenting (CAS). Embolic protection filters available for use during CAS include fixed and over-the-wire systems that rely on embolic material capture within a "basket" structure. The FiberNet Embolic Protection System (EPS), which features a very low crossing profile, consists of a three-dimensional fiber-based filter distally mounted on a 0.014 inch guidewire with integrated aspiration during filter retrieval. The trial enrolled 237 patients from 26 centers. Demographics, clinical and lesion characteristics, as well as adverse events through a 30-day follow-up were recorded. The mean age of the patients was 74 years, 64% were male and 20% had symptomatic carotid artery disease. The combined major adverse event (MAE) rate at 30 days for all death, stroke, and myocardial infarction was 3.0%. There were three major strokes (two ischemic and one hemorrhagic) and two minor strokes (both ischemic) for a 2.1% 30-day stroke rate. The procedural technical success rate was 97.5% and macroscopic evidence of debris was reported in 90.9% of the procedures. The FiberNet EPS, used with commercially available stents, produced low stroke rates following CAS in high surgical risk patients presenting with carotid artery disease. The unique filter design including aspiration during retrieval may have contributed to the low 30-day stroke rate reported during CAS in patients considered at high risk for complications following carotid endarterectomy (CEA). Copyright 2010 Wiley-Liss, Inc.

Aspects and Intensity of Pediatric Palliative Case Management Provided by a Hospital-Based Case Management Team: A Comparative Study Between Children With Malignant and Nonmalignant Disease

PubMed Central

Colenbrander, Derk A.; Bosman, Diederik K.; Grootenhuis, Martha A.; Kars, Marijke C.; Schouten-van Meeteren, Antoinette YN

2017-01-01

Objectives: Anticipating case management is considered crucial in pediatric palliative care. In 2012, our children’s university hospital initiated a specialized pediatric palliative care team (PPCT) to deliver inbound and outbound case management for children with life-shortening disease. The aim of this report is to gain insight in the first 9 months of this PPCT. Methods: Aspects of care during the first 9 months of the PPCT are presented, and comparison is made between patients with malignant disease (MD) and nonmalignant disease (NMD) in a retrospective study design. Insight in the aspects of care of all patients with a life-shortening disease was retrieved from web-based files and the hour registrations from the PPCT. Results: Forty-three children were supported by the PPCT during the first 9 months: 22 with MD with a median of 50 (1-267) days and 29 minutes (4-615) of case management per patient per day and 21 patients with NMD with a median of 79.5 (5-211) days and 16 minutes of case management per day (6-64). Our data show significantly more interprofessional contacts for patients with MD and more in-hospital contacts for patients with NMD. The median number of admission days per patient was 11 (0-22) for MD (44% for anticancer therapy) and 44 (0-303) for NMD (36% for infectious diseases). Significance of Results: This overview of aspects of pediatric palliative case management shows shorter but more intensive case management for MD in comparison with NMD. This insight in palliative case management guides the design of a PPCT. PMID:28273758

Delayed treatment of ruptured brain AVMs: is it ok to wait?

PubMed

Beecher, Jeffrey S; Lyon, Kristopher; Ban, Vin Shen; Vance, Awais; McDougall, Cameron M; Whitworth, Louis A; White, Jonathan A; Samson, Duke; Batjer, H Hunt; Welch, Babu G

2018-04-01

OBJECTIVE Despite a hemorrhagic presentation, many patients with arteriovenous malformations (AVMs) do not require emergency resection. The timing of definitive management is not standardized in the cerebrovascular community. This study was designed to evaluate the safety of delaying AVM treatment in clinically stable patients with a new hemorrhagic presentation. The authors examined the rate of rehemorrhage or neurological decline in a cohort of patients with ruptured brain AVMs during a period of time posthemorrhage. METHODS Patients presenting to the authors' institution from January 2000 to December 2015 with ruptured brain AVMs treated at least 4 weeks posthemorrhage were included in this analysis. Exclusion criteria were ruptured AVMs that required emergency surgery involving resection of the AVM, prior treatment of AVM at another institution, or treatment of lesions within 4 weeks for other reasons (subacute surgery). The primary outcome measure was time from initial hemorrhage to treatment failure (defined as rehemorrhage or neurological decline as a direct result of the AVM). Patient-days were calculated from the day of initial rupture until the day AVM treatment was initiated or treatment failed. RESULTS Of 102 ruptured AVMs in 102 patients meeting inclusion criteria, 7 (6.9%) failed the treatment paradigm. Six patients (5.8%) had a new hemorrhage within a median of 248 days (interquartile range 33-1364 days). The total "at risk" period was 18,740 patient-days, yielding a rehemorrhage rate of 11.5% per patient-year, or 0.96% per patient-month. Twelve (11.8%) of 102 patients were found to have an associated aneurysm. In this group there was a single (8.3%) new hemorrhage during a total at-risk period of 263 patient-days until the aneurysm was secured, yielding a rehemorrhage risk of 11.4% per patient-month. CONCLUSIONS It is the authors' practice to rehabilitate patients after brain AVM rupture with a plan for elective treatment of the AVM. The present data are useful in that the findings quantify the risk of the authors' treatment strategy. These findings indicate that delaying intervention for at least 4 weeks after the initial hemorrhage subjects the patient to a low (< 1%) risk of rehemorrhage. The authors modified the treatment paradigm when a high-risk feature, such as an associated intracranial aneurysm, was identified.

Solid electrolyte oxygen regeneration system

NASA Technical Reports Server (NTRS)

Shumar, J. W.; See, G. G.; Schubert, F. H.; Powell, J. D.

1976-01-01

A program to design, develop, fabricate and assemble a one-man, self-contained, solid electrolyte oxygen regeneration system (SX-1) incorporating solid electrolyte electrolyzer drums was completed. The SX-1 is a preprototype engineering model designed to produce 0.952 kg (2.1 lb)/day of breathable oxygen (O2) from the electrolysis of metabolic carbon dioxide (CO2) and water vapor. The CO2 supply rate was established based on the metabolic CO2 generation rate for one man of 0.998 kg (2.2 lb)/day. The water supply rate (0.254 kg (0.56 lb)/day) was designed to be sufficient to make up the difference between the 0.952 kg (2.1 lb)/day O2 generation specification and the O2 available through CO2 electrolysis, 0.726 kg (1.6 lb)/day. The SX-1 was successfully designed, fabricated and assembled. Design verification tests (DVT) or the CO Disproportionators, H2 separators, control instrumentation, monitor instrumentation, water feed mechanism were successfully completed. The erratic occurrence of electrolyzer drum leakage prevented the completion of the CO2 electrolyzer module and water electrolyzer module DVT's and also prevented the performance of SX-1 integrated testing. Further development work is required to improve the solid electrolyte cell high temperature seals.

The role of the central histaminergic receptors in the exercise-induced improvements of the spatial learning and memory in rats.

PubMed

Taati, Majid; Moghaddasi, Mehrnoush; Esmaeili, Masoumeh; Pourkhodadad, Soheila; Nayebzadeh, Hassan

2014-10-31

While it is well known that exercise can improve cognitive performance, the underlying mechanisms are not fully understood. There is now evidence that histamine can modulate learning and memory in different types of behavioral tasks. The present study was designed to examine the possible role of central histamine H1 and H2 receptors in forced treadmill running-induced enhancement of learning and memory in rats. For this purpose the animals received intracerebroventricularly chlorpheniramine (H1 receptor blocker) and cimetidine (H2 receptor blocker) before each day of fifteen consecutive days of exercise. Then their learning and memory were tested on the water maze task using a four-trial-per-day for 4 consecutive days. A probe trial was performed after the last training day. Our data showed that cimetidine reversed the exercise-induced improvement in learning and memory in rats; however, this was not the case regarding chlorpheniramine. Our findings indicate that central histamine H2 receptors play an important role in mediating the beneficial effects of forced exercise on learning and memory. Copyright © 2014 Elsevier B.V. All rights reserved.

The effects of oral consumption of selenium nanoparticles on chemotactic and respiratory burst activities of neutrophils in comparison with sodium selenite in sheep.

PubMed

Kojouri, Gholam Ali; Sadeghian, Sirous; Mohebbi, Abdonnaser; Mokhber Dezfouli, Mohammad Reza

2012-05-01

The present study was designed to compare the effects of nano-selenium and of sodium selenite on the chemotactic and respiratory burst activities of neutrophils in sheep. Fifteen sheep were randomly divided into three groups. Groups 1 and 2 received selenium nanoparticles (1 mg/kg) or sodium selenite (1 mg/kg) orally, respectively, for ten consecutive days, and the third group was considered as the control. To determine the chemotactic and respiratory burst activities of the neutrophils, the leading front assay and the NBT test were used on heparinized blood samples that were collected at different intervals (days 0, 10th, 20th, and 30th). The results obtained showed that the chemotactic activities in groups 1 and 2 increased significantly on the 10th, 20th, and 30th day, compared to day 0, and on the 20th day in comparison with the 10th day, while in group 2, there was a significant decrease on the 30th day compared to the 20th day. The chemotactic activities in group 1 were significantly higher than in group 2 on the 10th day and in the control group on the 10th, 20th, and 30th day, but the chemotactic activities in group 2 were significantly higher than those in the control group only on the 20th day. On the 30th day into the experiment, the respiratory bursts in groups 1 and 2 were significantly stronger in comparison with those at day 0. Overall, nano-selenium increased the chemotactic and respiratory burst activities more significantly than sodium selenite, which is suggestive of a stronger stimulatory effect of the Se nanoparticles on intracellular activities.

Projected Changes in Temperature and Precipitation Extremes over China as Measured by 50-yr Return Values and Periods Based on a CMIP5 Ensemble

NASA Astrophysics Data System (ADS)

Xu, Ying; Gao, Xuejie; Giorgi, Filippo; Zhou, Botao; Shi, Ying; Wu, Jie; Zhang, Yongxiang

2018-04-01

Future changes in the 50-yr return level for temperature and precipitation extremes over mainland China are investigated based on a CMIP5 multi-model ensemble for RCP2.6, RCP4.5 and RCP8.5 scenarios. The following indices are analyzed: TXx and TNn (the annual maximum and minimum of daily maximum and minimum surface temperature), RX5day (the annual maximum consecutive 5-day precipitation) and CDD (maximum annual number of consecutive dry days). After first validating the model performance, future changes in the 50-yr return values and return periods for these indices are investigated along with the inter-model spread. Multi-model median changes show an increase in the 50-yr return values of TXx and a decrease for TNn, more specifically, by the end of the 21st century under RCP8.5, the present day 50-yr return period of warm events is reduced to 1.2 yr, while extreme cold events over the country are projected to essentially disappear. A general increase in RX5day 50-yr return values is found in the future. By the end of the 21st century under RCP8.5, events of the present RX5day 50-yr return period are projected to reduce to < 10 yr over most of China. Changes in CDD-50 show a dipole pattern over China, with a decrease in the values and longer return periods in the north, and vice versa in the south. Our study also highlights the need for further improvements in the representation of extreme events in climate models to assess the future risks and engineering design related to large-scale infrastructure in China.

Contact Patterns among High School Students

PubMed Central

Fournet, Julie; Barrat, Alain

2014-01-01

Face-to-face contacts between individuals contribute to shape social networks and play an important role in determining how infectious diseases can spread within a population. It is thus important to obtain accurate and reliable descriptions of human contact patterns occurring in various day-to-day life contexts. Recent technological advances and the development of wearable sensors able to sense proximity patterns have made it possible to gather data giving access to time-varying contact networks of individuals in specific environments. Here we present and analyze two such data sets describing with high temporal resolution the contact patterns of students in a high school. We define contact matrices describing the contact patterns between students of different classes and show the importance of the class structure. We take advantage of the fact that the two data sets were collected in the same setting during several days in two successive years to perform a longitudinal analysis on two very different timescales. We show the high stability of the contact patterns across days and across years: the statistical distributions of numbers and durations of contacts are the same in different periods, and we observe a very high similarity of the contact matrices measured in different days or different years. The rate of change of the contacts of each individual from one day to the next is also similar in different years. We discuss the interest of the present analysis and data sets for various fields, including in social sciences in order to better understand and model human behavior and interactions in different contexts, and in epidemiology in order to inform models describing the spread of infectious diseases and design targeted containment strategies. PMID:25226026

An overview of “The Active by Choice Today” (ACT) trial for increasing physical activity✩

PubMed Central

Wilson, Dawn K.; Kitzman-Ulrich, Heather; Williams, Joel E.; Saunders, Ruth; Griffin, Sarah; Pate, Russell; Van Horn, M. Lee; Evans, Alexandra; Hutto, Brent; Addy, Cheryl L.; Mixon, Gary; Sisson, Susan B.

2008-01-01

Background: Although school-based behavioral interventions for increasing physical activity (PA) in children and adolescents have been conducted, little evidence suggests that these curriculum-based approaches lead to increases in overall activity outside of program days. The overall goal of the “Active by Choice Today” (ACT) trial is to expand the body of knowledge concerning the factors that influence long-term increases in PA in underserved adolescents (low socioeconmic status, minorities) during their middle school years. Design and setting: An overview of the ACT study design, theoretical framework, process evaluation, and primary hypotheses is presented. The trial involves twenty-four middle schools (1560 6th graders) in South Carolina that are randomly assigned to one of two after-school programs (motivational and life skills intervention, or general health education). Intervention: The intervention integrates constructs from Self-Determination and Social Cognitive Theories to enhance intrinsic motivation and behavioral skills for PA. The intervention targets skill development for PA outside of program days and the after-school program social environment (autonomy, choice, participation, belongingness, fun, enjoyment, support) is designed to positively impact cognitive mediators (self-efficacy, perceived competence), and motivational orientation (intrinsic motivation, commitment, positive self-concept). Main hypotheses/outcomes: It is hypothesized that the 17-week motivational and life skills intervention will lead to greater increases in moderate-to-vigorous PA (based on 7-day accelerometry estimates) at post-intervention as compared to the general health education program. Conclusions: Implications of this innovative school-based trial are discussed. PMID:17716952

Sampling Considerations for Designing Aedes aegypti (Diptera: Culicidae) Oviposition Studies in Iquitos, Peru: Substrate Preference, Diurnal Periodicity, and Gonotrophic Cycle Length

PubMed Central

WONG, JACKLYN; ASTETE, HELVIO; MORRISON, AMY C.; SCOTT, THOMAS W.

2011-01-01

When devising methods to sample Aedes aegypti (L.) eggs from naturally-occurring containers to investigate selective oviposition, failure to take into account certain aspects of Ae. aegypti behavior can bias study inferences. In Iquitos, Peru, we tested three assumptions related to designing Ae. aegypti oviposition field studies, as follows: 1) lining containers with paper as an oviposition substrate does not affect oviposition; 2) diurnal egg-laying activity peaks in the late afternoon or early evening, and there is little oviposition during midday; and 3) the gonotrophic cycle length of wild females averages from 3 to 4 d. When wild females were presented with containers lined and unlined with paper toweling, the presence of paper increased oviposition in plastic and metal containers, but had no effect in cement containers. Recording the number of eggs laid by Ae. aegypti every 2 h throughout the day delineated a bimodal diurnal oviposition pattern, with a small morning peak, decreased activity during midday, and a predominant peak in the late afternoon and evening from 16:00 to 20:00 h. Daily monitoring of captive individual F0 females revealed that the gonotrophic cycle length was typically 3– 4 d for the Iquitos population. These findings will be used to adjust field study design to 1) account for sampling eggs using paper toweling, and 2) determine the time of day and number of days over which to sample Ae. aegypti eggs. We explored how failure to consider these behaviors could potentially bias field assessments of oviposition preferences. PMID:21337947

Semi-annual report of the Department of Energy, Office of Environmental Management, Quality Assessment Program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greenlaw, P.D.; Minick, S.K.

This Quality Assessment Program (QAP) is designed to test the quality of the environmental measurements being reported to the Department of Energy by its contractors. Since 1976, real or synthetic environmental samples that have been prepared and thoroughly analyzed at the Environmental Measurements Laboratory (EML) have been distributed at first quarterly and then semi-annually to these contractors. Their results, which are returned to EML within 90 days, are compiled with EML`s results and are reported back to the participating contractors 30 days later. This report presents the results from the analysis of the 48th set of environmental quality assessment samplesmore » (QAP XLVIII) that were received on or before June 1, 1998.« less

Effect of socioeconomic disadvantage, remoteness and Indigenous status on hospital usage for Western Australian preterm infants under 12 months of age: a population-based data linkage study

PubMed Central

Strobel, Natalie A; Peter, Sue; McAuley, Kimberley E; McAullay, Daniel R; Marriott, Rhonda; Edmond, Karen M

2017-01-01

Objectives Our primary objective was to determine the incidence of hospital admission and emergency department presentation in Indigenous and non-Indigenous preterm infants aged postdischarge from birth admission to 11 months in Western Australia. Secondary objectives were to assess incidence in the poorest infants from remote areas and to determine the primary causes of hospital usage in preterm infants. Design Prospective population-based linked data set. Setting and participants All preterm babies born in Western Australia during 2010 and 2011. Main outcome measures All-cause hospitalisations and emergency department presentations. Results There were 6.9% (4211/61 254) preterm infants, 13.1% (433/3311) Indigenous preterm infants and 6.5% (3778/57 943) non-Indigenous preterm infants born in Western Australia. Indigenous preterm infants had a higher incidence of hospital admission (adjusted incident rate ratio (aIRR) 1.24, 95% CI 1.08 to 1.42) and emergency department presentation (aIRR 1.71, 95% CI 1.44 to 2.02) compared with non-Indigenous preterm infants. The most disadvantaged preterm infants (7.8/1000 person days) had a greater incidence of emergency presentation compared with the most advantaged infants (3.1/1000 person days) (aIRR 1.61, 95% CI 1.30 to 2.00). The most remote preterm infants (7.8/1000 person days) had a greater incidence of emergency presentation compared with the least remote preterm infants (3.0/1000 person days; aIRR 1.82, 95% CI 1.49 to 2.22). Conclusions In Western Australia, preterm infants have high hospital usage in their first year of life. Infants living in disadvantaged areas, remote area infants and Indigenous infants are at increased risk. Our data highlight the need for improved postdischarge care for preterm infants. PMID:28100563

Transmission of Porcine reproductive and respiratory syndrome virus 1 to and from vaccinated pigs in a one-to-one model.

PubMed

Pileri, E; Gibert, E; Martín-Valls, G E; Nofrarias, M; López-Soria, S; Martín, M; Díaz, I; Darwich, L; Mateu, E

2017-03-01

The present study examined transmission by contact of Porcine reproductive and respiratory syndrome virus (PRRSV) 1 in a one-to-one model to vaccinated and unvaccinated pigs and from vaccinated infected pigs to other vaccinated pigs. The experiment started by randomly assigning weaned pigs to groups V (n=24) and U (n=26). V pigs were vaccinated with a commercial live attenuated PRRSV vaccine and the U animals were kept as unvaccinated controls. Twenty-eight days later, 6U pigs were separated and allocated in individual boxes. The remaining 20U pigs were intranasally inoculated with PRRSV isolate 3267 (from now on designated as seeder (S) pigs) and 48h later were distributed in boxes where they were commingled with either V or U pigs in 1:1 groups (first contact phase), resulting in 6S:U and 14S:V pairs. As soon as a V pig was detected to be viremic because of contact with a S, the infected V (from now on designated as V inf ) was transferred (<24h after detection) to a new pen where it was comingled with a new V pig (designated as V 2 ) in a second contact phase. For the first contact phase, pigs were maintained 21days at maximum and for the second contact phase the maximum exposure period was 14days. Two V pigs tested positive for the vaccine virus (>99.5% similarity) when they were relocated with the corresponding V 2 pigs and they were removed; thus, only 12V inf were finally considered. All V pigs (12/12) exposed to S animals became infected although the first detection of viremia occurred at 13.6±3.6days, one week later than in U (p<0.05). Also, duration of viremia was shorter for V inf compared to U, (5.5±4.3days versus 12.5±2.7days). The V inf group showed remarkable individual variability: eight animals had a viremic period of 5 or less days (3.0±1.4) while the remaining four had a longer viremic period of more than one week (10.8±2.9). This situation was not observed in U. In the second contact phase, transmission from V inf to V 2 pigs occurred in 7/8 cases (87.5%). The mean duration of viremia for V 2 was 4.8±3.4 and two different patterns were again observed: two animals had viremias of 9-10days and the rest averaged 3.0±1.4days (range: 2-5days). Vaccinated groups V inf and V 2 had a significantly lower PRRSV shedding in oral fluids for at least the first 9days after the onset of the viremia compared to U, and shedding for V2 was even significantly lower (p<0.05) than shedding for V inf . Our experimental design reproduced the worst-case scenario for evaluating the effect of vaccination and, under such conditions; it was still efficacious in slowering PRRSV transmission and decreasing the global viral load and particularly oral shedding. Copyright © 2016. Published by Elsevier B.V.

Spacecraft telecommunications system mass estimates

NASA Technical Reports Server (NTRS)

Yuen, J. H.; Sakamoto, L. L.

1988-01-01

Mass is the most important limiting parameter for present-day planetary spacecraft design, In fact, the entire design can be characterized by mass. The more efficient the design of the spacecraft, the less mass will be required. The communications system is an essential and integral part of planetary spacecraft. A study is presented of the mass attributable to the communications system for spacecraft designs used in recent missions in an attempt to help guide future design considerations and research and development efforts. The basic approach is to examine the spacecraft by subsystem and allocate a portion of each subsystem to telecommunications. Conceptually, this is to divide the spacecraft into two parts, telecommunications and nontelecommunications. In this way, it is clear what the mass attributable to the communications system is. The percentage of mass is calculated using the actual masses of the spacecraft parts, except in the case of CRAF. In that case, estimated masses are used since the spacecraft was not yet built. The results show that the portion of the spacecraft attributable to telecommunications is substantial. The mass fraction for Voyager, Galileo, and CRAF (Mariner Mark 2) is 34, 19, and 18 percent, respectively. The large reduction of telecommunications mass from Voyager to Galileo is mainly due to the use of a deployable antenna instead of the solid antenna on Voyager.

Experimental design data for the biosynthesis of citric acid using Central Composite Design method.

PubMed

Kola, Anand Kishore; Mekala, Mallaiah; Goli, Venkat Reddy

2017-06-01

In the present investigation, we report that statistical design and optimization of significant variables for the microbial production of citric acid from sucrose in presence of filamentous fungi A. niger NCIM 705. Various combinations of experiments were designed with Central Composite Design (CCD) of Response Surface Methodology (RSM) for the production of citric acid as a function of six variables. The variables are; initial sucrose concentration, initial pH of medium, fermentation temperature, incubation time, stirrer rotational speed, and oxygen flow rate. From experimental data, a statistical model for this process has been developed. The optimum conditions reported in the present article are initial concentration of sucrose of 163.6 g/L, initial pH of medium 5.26, stirrer rotational speed of 247.78 rpm, incubation time of 8.18 days, fermentation temperature of 30.06 °C and flow rate of oxygen of 1.35 lpm. Under optimum conditions the predicted maximum citric acid is 86.42 g/L. The experimental validation carried out under the optimal values and reported citric acid to be 82.0 g/L. The model is able to represent the experimental data and the agreement between the model and experimental data is good.

A Fully Implantable Pacemaker for the Mouse: From Battery to Wireless Power

PubMed Central

Zellmer, Erik R.; Weinheimer, Carla J.; MacEwan, Matthew R.; Cui, Sophia X.; Nerbonne, Jeanne M.; Efimov, Igor R.

2013-01-01

Animal models have become a popular platform for the investigation of the molecular and systemic mechanisms of pathological cardiovascular physiology. Chronic pacing studies with implantable pacemakers in large animals have led to useful models of heart failure and atrial fibrillation. Unfortunately, molecular and genetic studies in these large animal models are often prohibitively expensive or not available. Conversely, the mouse is an excellent species for studying molecular mechanisms of cardiovascular disease through genetic engineering. However, the large size of available pacemakers does not lend itself to chronic pacing in mice. Here, we present the design for a novel, fully implantable wireless-powered pacemaker for mice capable of long-term (>30 days) pacing. This design is compared to a traditional battery-powered pacemaker to demonstrate critical advantages achieved through wireless inductive power transfer and control. Battery-powered and wireless-powered pacemakers were fabricated from standard electronic components in our laboratory. Mice (n = 24) were implanted with endocardial, battery-powered devices (n = 14) and epicardial, wireless-powered devices (n = 10). Wireless-powered devices were associated with reduced implant mortality and more reliable device function compared to battery-powered devices. Eight of 14 (57.1%) mice implanted with battery-powered pacemakers died following device implantation compared to 1 of 10 (10%) mice implanted with wireless-powered pacemakers. Moreover, device function was achieved for 30 days with the wireless-powered device compared to 6 days with the battery-powered device. The wireless-powered pacemaker system presented herein will allow electrophysiology studies in numerous genetically engineered mouse models as well as rapid pacing-induced heart failure and atrial arrhythmia in mice. PMID:24194832

Status of the ITER Electron Cyclotron Heating and Current Drive System

DOE Office of Scientific and Technical Information (OSTI.GOV)

Darbos, Caroline; Albajar, Ferran; Bonicelli, Tullio

2015-10-07

We present that the electron cyclotron (EC) heating and current drive (H&CD) system developed for the ITER is made of 12 sets of high-voltage power supplies feeding 24 gyrotrons connected through 24 transmission lines (TL), to five launchers, four located in upper ports and one at the equatorial level. Nearly all procurements are in-kind, following general ITER philosophy, and will come from Europe, India, Japan, Russia and the USA. The full system is designed to couple to the plasma 20 MW among the 24 MW generated power, at the frequency of 170 GHz, for various physics applications such as plasmamore » start-up, central H&CD and magnetohydrodynamic (MHD) activity control. The design takes present day technology and extends toward high-power continuous operation, which represents a large step forward as compared to the present state of the art. The ITER EC system will be a stepping stone to future EC systems for DEMO and beyond.The development of the EC system is facing significant challenges, which includes not only an advanced microwave system but also compliance with stringent requirements associated with nuclear safety as ITER became the first fusion device licensed as basic nuclear installations as of 9 November 2012. Finally, since the conceptual design of the EC system was established in 2007, the EC system has progressed to a preliminary design stage in 2012 and is now moving forward toward a final design.« less

NESTA Revolutionizing Teacher's Experiences at NSTA Conventions

NASA Astrophysics Data System (ADS)

Ireton, F.

2002-05-01

National Science Teachers Association (NSTA) conventions are traditionally composed of short workshops, half or full day workshops, and lectures on science teaching or education research. Occasional science lectures such as the AGU lecture offer science content information. The National Earth Science Teachers Association (NESTA) will join the National Association of Geoscience Teachers (NAGT), American Geophysical Union (AGU), and the American Geological Institute (AGI) to bring teachers a suite of exciting and informative events at the (NSTA) 2002 convention. Events begin with a guided learning field trip to Mission Trails Regional Park and Torrey Pines State Reserve where Earth and space science teachers experience a model of constructivist leaning techniques. Most field trips are a "show and tell" experience, designed to transmit knowledge from the field trip leader to the field trip participants. In the "guided learning" environment, the leader serves as a facilitator, asking questions, guiding participants to discover concepts for themselves. Participants examine selected processes and features that constitute a constructivist experience in which knowledge acquired at any given location builds on knowledge brought to the site. Employing this strategy involves covering less breadth but greater depth, modeling the concept of "less is more." On Thursday NESTA will host two Share-a-thons. These are not what a person would think of as a traditional workshop where presenter makes a presentation then the participants work on an activity. They could be called the flea market of teaching ideas. Tables are set around the perimeter of a room where the presenters are stationed. Teachers move from table to table picking up information and watching short demonstrations. The Earth and Space Science Resource Day on Friday will focus on teachers needs. Starting with breakfast, teachers will hear from Soames Summerhays, Naturalist and President of Summerhays Films, about how he works science and education into the making of IMAXr films. After breakfast, NESTA and NAGT members team up for a joint Share-a-thon. Three AGU sponsored scientists discussing their research follow the Share-a-thon. These presentations are designed to provide teachers with up-to-date content information. A highlight of the day will be the NESTA rock raffle of over 100 specimens.

Technology advancement of the static feed water electrolysis process

NASA Technical Reports Server (NTRS)

Jensen, F. C.; Schubert, F. H.

1977-01-01

Some results are presented of a research and development program to continue the development of a method to generate oxygen for crew metabolic consumption during extended manned space flights. The concept being pursued is that of static feed water electrolysis. Specific major results of the work included: (1) completion of a 30-day electrode test using a Life Systems, Inc.-developed high performance catalyst. During startup the cell voltages were as low as 1.38 V at current densities of 108 mA/sq cm (100 ASF) and temperatures of 355 K (180 F). At the end of 30 days of testing the cell voltages were still only 1.42 V at 108 mA/sq cm, (2) determination that the Static Feed Water Electrolysis Module does not release an aerosol of the cell electrolyte into the product gas streams after a break-in period of 24 hours following a new electrolyte charge, and (3) completion of a detailed design analysis of an electrochemical Oxygen Generation Subsystem at a three-man level (4.19 kg/day (9.24 lb/day) of oxygen).

A pilot study on mindfulness based stress reduction for smokers

PubMed Central

Davis, James M; Fleming, Michael F; Bonus, Katherine A; Baker, Timothy B

2007-01-01

Background Mindfulness means paying attention in the present moment, non-judgmentally, without commentary or decision-making. We report results of a pilot study designed to test the feasibility of using Mindfulness Based Stress Reduction (MBSR) (with minor modifications) as a smoking intervention. Methods MBSR instructors provided instructions in mindfulness in eight weekly group sessions. Subjects attempted smoking cessation during week seven without pharmacotherapy. Smoking abstinence was tested six weeks after the smoking quit day with carbon monoxide breath test and 7-day smoking calendars. Questionnaires were administered to evaluate changes in stress and affective distress. Results 18 subjects enrolled in the intervention with an average smoking history of 19.9 cigarettes per day for 26.4 years. At the 6-week post-quit visit, 10 of 18 subjects (56%) achieved biologically confirmed 7-day point-prevalent smoking abstinence. Compliance with meditation was positively associated with smoking abstinence and decreases in stress and affective distress. Discussions and conclusion The results of this study suggest that mindfulness training may show promise for smoking cessation and warrants additional study in a larger comparative trial. PMID:17254362

A pilot study on mindfulness based stress reduction for smokers.

PubMed

Davis, James M; Fleming, Michael F; Bonus, Katherine A; Baker, Timothy B

2007-01-25

Mindfulness means paying attention in the present moment, non-judgmentally, without commentary or decision-making. We report results of a pilot study designed to test the feasibility of using Mindfulness Based Stress Reduction (MBSR) (with minor modifications) as a smoking intervention. MBSR instructors provided instructions in mindfulness in eight weekly group sessions. Subjects attempted smoking cessation during week seven without pharmacotherapy. Smoking abstinence was tested six weeks after the smoking quit day with carbon monoxide breath test and 7-day smoking calendars. Questionnaires were administered to evaluate changes in stress and affective distress. 18 subjects enrolled in the intervention with an average smoking history of 19.9 cigarettes per day for 26.4 years. At the 6-week post-quit visit, 10 of 18 subjects (56%) achieved biologically confirmed 7-day point-prevalent smoking abstinence. Compliance with meditation was positively associated with smoking abstinence and decreases in stress and affective distress. The results of this study suggest that mindfulness training may show promise for smoking cessation and warrants additional study in a larger comparative trial.

A novel approach for assessing the progression of deep venous thrombosis by area of venous thrombus in ultrasonic elastography.

PubMed

Wang, Chao; Wang, Lei; Zhang, Yuhui; Chen, Ming

2014-04-01

Exact age determination of deep venous thrombosis (DVT) is important for an appropriate treatment. The purpose of this present study is to assess the age of acute DVT with the area of venous thrombi in elasticity imaging during the thrombosis procession. The thrombus area is obtained from a specially designed program. It was applied to clot specimens induced in human great saphenous (n = 15) at selected time points following the initiation of thrombosis. The relative mean proportion of blood clots was 50.01% ± 12.44% at day 1; 69.94% ± 8.19% at day 3; 81.93% ± 6.15% at day 6; and 92.37% ± 4.06% at day 9. The results indicated that the thrombus area increased significantly over time, while the normalized strain values inside the thrombus changed only a little. The pathological analyses also showed the same results. Therefore, we conclude that the area of venous thrombi in elasticity imaging may be a novel function for acute DVT staging.

Effect of apitherapy in piglets with preweaning diarrhea.

PubMed

Choi, Seok Hwa; Cho, Seong Koo; Kang, Seong Soo; Bae, Chun Sik; Bai, Young Hoon; Lee, Seung Hoo; Pak, Sok Cheon

2003-01-01

This study was designed to examine the therapeutic effect of honeybee (Apis mellifera L.) venom in piglets with bacterial diarrhea Comparison between bee venom- and drug-treated groups was our main concern in the present study. Preweaning piglets were assigned to treated and non-treated control groups. In the treated group, 47 piglets were acupunctured with the worker honeybee once a day for three consecutive days. Two acupoints, GV-1 (Jiao-chao) and ST-25 (Hai-men), were selected for apitherapy. In the control group, 44 piglets were intramuscularly injected with a standard dose of a known antibacterial drug, colistin sulfate (300,000 IU/kg of body weight), and an antidiarrheal drug (berberine, 2 ml/kg) once a day for three consecutive days. At post-treatment, 90.9% of the control piglets and 93.6% of piglets in the treated group recovered from bacterial diarrhea. Bee acupuncture therapy did not show any side effects such as allergy, intoxication, hemorrhage or infection. It is concluded that bee venom therapy was effective in controlling bacterial diarrhea in preweaning piglets.

Status of the ITER Electron Cyclotron Heating and Current Drive System

NASA Astrophysics Data System (ADS)

Darbos, Caroline; Albajar, Ferran; Bonicelli, Tullio; Carannante, Giuseppe; Cavinato, Mario; Cismondi, Fabio; Denisov, Grigory; Farina, Daniela; Gagliardi, Mario; Gandini, Franco; Gassmann, Thibault; Goodman, Timothy; Hanson, Gregory; Henderson, Mark A.; Kajiwara, Ken; McElhaney, Karen; Nousiainen, Risto; Oda, Yasuhisa; Omori, Toshimichi; Oustinov, Alexander; Parmar, Darshankumar; Popov, Vladimir L.; Purohit, Dharmesh; Rao, Shambhu Laxmikanth; Rasmussen, David; Rathod, Vipal; Ronden, Dennis M. S.; Saibene, Gabriella; Sakamoto, Keishi; Sartori, Filippo; Scherer, Theo; Singh, Narinder Pal; Strauß, Dirk; Takahashi, Koji

2016-01-01

The electron cyclotron (EC) heating and current drive (H&CD) system developed for the ITER is made of 12 sets of high-voltage power supplies feeding 24 gyrotrons connected through 24 transmission lines (TL), to five launchers, four located in upper ports and one at the equatorial level. Nearly all procurements are in-kind, following general ITER philosophy, and will come from Europe, India, Japan, Russia and the USA. The full system is designed to couple to the plasma 20 MW among the 24 MW generated power, at the frequency of 170 GHz, for various physics applications such as plasma start-up, central H&CD and magnetohydrodynamic (MHD) activity control. The design takes present day technology and extends toward high-power continuous operation, which represents a large step forward as compared to the present state of the art. The ITER EC system will be a stepping stone to future EC systems for DEMO and beyond.

Spillover between interparental conflict and parent-child conflict within and across days.

PubMed

Sherrill, Rachel Baden; Lochman, John E; DeCoster, Jamie; Stromeyer, Sara L

2017-10-01

The present study used a daily reporting design to examine the bidirectional spillover in conflict and conflict strategies between the interparental relationship and the parent-child relationship. Participants were 60 parents with a preadolescent child at risk for aggressive behavior. Parents reported on their experience of interparental and parent-child conflict and their use of constructive and destructive conflict strategies through daily telephone interviews over 7 days. Each day was divided into 3 equal time periods roughly corresponding to early morning, daytime, and evening. Time-lagged analyses investigated the spillover in conflict within and across days. Results revealed that the presence of interparental conflict significantly predicted the presence of parent-child conflict 1 time period later and 1 full day later. Likewise, the presence of parent-child conflict significantly predicted the presence of interparental conflict 1 full day later. In terms of conflict strategy use, results revealed that parents who engaged in constructive patterns of interparental conflict were more likely to engage in constructive patterns of parent-child conflict 1 time period later and 1 full day later. Reciprocal effects for constructive parent-child conflict predicting subsequent interparental conflict were significant across all 3 time lags assessed. There were no significant, bidirectional effects for the spillover in destructive conflict. Findings have important clinical implications. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Liquid belt radiator design study

NASA Technical Reports Server (NTRS)

Teagan, W. P.; Fitzgerald, K. F.

1986-01-01

The Liquid Belt Radiator (LBR) is an advanced concept developed to meet the needs of anticipated future space missions. A previous study documented the advantages of this concept as a lightweight, easily deployable alternative to present day space heat rejection systems. The technical efforts associated with this study concentrate on refining the concept of the LBR as well as examining the issues of belt dynamics and potential application of the LBR to intermediate and high temperature heat rejection applications. A low temperature point design developed in previous work is updated assuming the use of diffusion pump oil, Santovac-6, as the heat transfer media. Additional analytical and design effort is directed toward determining the impact of interface heat exchanger, fluid bath sealing, and belt drive mechanism designs on system performance and mass. The updated design supports the earlier result by indicating a significant reduction in system specific system mass as compared to heat pipe or pumped fluid radiator concepts currently under consideration (1.3 kg/sq m versus 5 kg/sq m).

The KIzSS network, a sentinel surveillance system for infectious diseases in day care centers: study protocol

PubMed Central

2012-01-01

Background Day care-associated infectious diseases are widely recognized as a public health problem but rarely studied. Insights into their dynamics and their association with the day care setting are important for effective decision making in management of infectious disease control. This paper describes the purpose, design and potential of our national multi-center, day care-based sentinel surveillance network for infectious diseases (the KIzSS network). The aim of the KIzSS network is to acquire a long-term insight into the syndromic and microbiological aspects of day care-related infectious diseases and associated disease burden and to model these aspects with day care setting characteristics. Methods/design The KIzSS network applies a prospective cohort design, following day care centers rather than individual children or staff members over time. Data on infectious disease symptoms and related morbidity (children and staff), medical consumption, absenteeism and circulating enteric pathogens (children) are collected on a daily, weekly or monthly basis. Every two years, a survey is performed to assess the characteristics of participating day care centers. Discussion The KIzSS network offers a unique potential to study infectious disease dynamics in the day care setting over a sustained period of time. The created (bio)databases will help us to assess day care-related disease burden of infectious diseases among attending children and staff and their relation with the day care setting. This will support the much needed development of evidence-based and pragmatic guidelines for infectious disease control in day care centers. PMID:23066727

The FIT Game: preliminary evaluation of a gamification approach to increasing fruit and vegetable consumption in school.

PubMed

Jones, Brooke A; Madden, Gregory J; Wengreen, Heidi J

2014-11-01

Incentive-based interventions designed to increase fruit and vegetable (FV) consumption tend to yield positive, short-term outcomes. Because consumption most often returns to baseline levels when incentives are removed, sustainable long-duration interventions may be needed to impact public health. Anticipating that low-cost interventions will be more appealing to schools, the present study explored a low-cost, game-based intervention. An alternating-treatments design was used to evaluate the effects of the FIT Game on objectively measured FV consumption in one elementary school (n=251) in Utah. During the Fall 2013 semester, game-based rewards were provided to heroic characters within a fictional narrative read by teachers on days when the school, as a whole, met a fruit or vegetable consumption goal in accord with the alternating-treatments design. On intervention days, fruit and vegetable consumption increased by 39% and 33%, (p<0.01, p<0.05; binomial tests), respectively. Teacher surveys indicated that students enjoyed the game and grade 1-3 teachers recommended its use in other schools. This game-based intervention provides a promising step towards developing a low-cost, effective, and sustainable FV intervention that schools can implement without outside assistance. Copyright © 2014 Elsevier Inc. All rights reserved.

Design of a fast crew transfer vehicle to Mars

NASA Technical Reports Server (NTRS)

1988-01-01

A final report is made on the trajectory and vehicle requirements for a fast crew transfer vehicle to Mars which will complete an Earth to Mars (and Mars to Earth) transfer in 150 days and will have a stay time at Mars of 40 days. This vehicle will maximize the crew's effectiveness on Mars by minimizing detrimental physiological effects such as bone demineralization and loss of muscle tone caused by long period exposure to zero gravity and radiation from cosmic rays and solar flares. The crew transfer vehicle discussed will complete the second half of a Split Mission to Mars. In the Split Mission, a slow, unmanned cargo vehicle, nicknamed the Barge, is sent to Mars ahead of the crew vehicle. Once the Barge is in orbit around Mars, the fast crew vehicle will be launched to rendezvous with the Barge in Mars orbit. The vehicle presented is designed to carry six astronauts for a mission duration of one year. The vehicle uses a chemical propulsion system and a nuclear power system. Four crew modules, similar to the proposed Space Station Common Modules, are used to house the crew and support equipment during the mission. The final design also includes a command module that is shielded to protect the crew during radiation events.

Plans and Considerations for the Exploration of Space

NASA Technical Reports Server (NTRS)

Derkowski, Brian J.

2001-01-01

The Mars Settlement Design Competition is a program for high school students and teachers to experience the process of mission and hardware design. It provides a top level view into how NASA plans to explore space. I will be involved with all three days of this competition. On Friday I plan to give two presentations, one to the employees of White Sands Test Facility and one to students and teachers. On Saturday, I will have a question and answer session with some of the teachers participating in the workshop. Sunday I will serve as one of the judges that will review the students projects created over the weekend. The main emphasis of my talk will focus on exploring the possibilities of the future of space exploration. I will discuss the Mars Reference Mission 3.0, as well as some of the current robotic missions being sent to Mars. Next, I will present a business model perfected by Hum Mandell, showing how the public, private, and commercial sectors all play a major role in sending humans to Mars. I will also discuss the work of the Integrated Design Team at JSC and how that working together approach is key for a successful design. Finally, I will present that the question of how humans can reach out beyond low earth orbit and place permanent settlements on Mars is really a function of the imagination of those who intend on going there.

A vision for chronic disease prevention intervention research: report from a workshop.

PubMed

Ashbury, Frederick D; Little, Julian; Ioannidis, John P A; Kreiger, Nancy; Palmer, Lyle J; Relton, Clare; Taylor, Peter

2014-04-17

The Population Studies Research Network of Cancer Care Ontario hosted a strategic planning workshop to establish an agenda for a prevention intervention research program in Ontario, including priority topics for investigation and design considerations. The two-day workshop included: presentations on background papers developed to facilitate participants' preparation for and discussions in the workshop; keynote presentations on intervention research concerning primary prevention of chronic diseases, design and study implementation considerations; a dedicated session on critical and creative thinking to stimulate participation and discussion topics; break out groups to identify, discuss and present study ideas, designs, implementation considerations; and a consensus process to discuss and identify recommendations for research priorities and next steps. The retreat yielded the following recommendations: 1) develop an intervention research agenda that includes working with existing large-scale cohorts; 2) develop an intervention research agenda that includes novel research designs that could target individuals or groups; and 3) develop an intervention research agenda in which studies collect data on costs, define stakeholders, and ensure clear strategies for stakeholder engagement and knowledge transfer. The Population Studies Research Network will develop options from these recommendations and release a call for proposals in 2014 for intervention research pilot projects that reflect these recommendations. Pilot projects will be evaluated based on their fit with the retreat's recommendations, and their potential to scale up to full studies and application in practice.

Energy saving through LED in signaling functions for automotive exterior lighting

NASA Astrophysics Data System (ADS)

Bony, Alexis; Hamami, Khaled; Tebbe, Frank; Mertens, Jens

2011-05-01

Safety considerations have always driven the way for improving exterior automotive lighting legal requirements. With the recent adoption of day-time running lamps for passenger cars, the steadily increasing need for reduction of vehicle power consumption has led to the introduction of LED-based day-time running lamps. Solutions with incandescent bulbs have also been implemented, as they present price advantages while offering limited design perspectives. In the meantime, technology developments has turned LED sources into ideal candidates for daytime running lamps by increasing their lumen per watt efficiency ratio towards values around 100 lm/W or higher. In this work, taking as an example the new Mercedes-Benz roadster SLK (R172), we present the first single LED daytime- running lamp, with a total power consumption below 5W per vehicle. After reviewing legal requirements, the optical and electronic concepts are discussed. Details on the tail lamp LED functions are also discussed, and particularly the advantages from the realization of fog lamp with LEDs.

Power inversion design for ocean wave energy harvesting

NASA Astrophysics Data System (ADS)

Talebani, Anwar N.

The needs for energy sources are increasing day by day because of several factors, such as oil depletion, and global climate change due to the higher level of CO2, so the exploration of various renewable energy sources is very promising area of study. The available ocean waves can be utilized as free source of energy as the water covers 70% of the earth surface. This thesis presents the ocean wave energy as a source of renewable energy. By addressing the problem of designing efficient power electronics system to deliver 5 KW from the induction generator to the grid with less possible losses and harmonics as possible and to control current fed to the grid to successfully harvest ocean wave energy. We design an AC-DC full bridge rectifier converter, and a DC-DC boost converter to harvest wave energy from AC to regulated DC. In order to increase the design efficiency, we need to increase the power factor from (0.5-0.6) to 1. This is accomplished by designing the boost converter with power factor correction in continues mode with RC circuit as an input to the boost converter power factor correction. This design results in a phase shift between the input current and voltage of the full bridge rectifier to generate a small reactive power. The reactive power is injected to the induction generator to maintain its functionality by generating a magnetic field in its stator. Next, we design a single-phase pulse width modulator full bridge voltage source DC-AC grid-tied mode inverter to harvest regulated DC wave energy to AC. The designed inverter is modulated by inner current loop, to control current injected to the grid with minimal filter component to maintain power quality at the grid. The simulation results show that our design successfully control the current level fed to the grid. It is noteworthy that the simulated efficiency is higher than the calculated one since we used an ideal switch in the simulated circuit.

An XML-based method for astronomy software designing

NASA Astrophysics Data System (ADS)

Liao, Mingxue; Aili, Yusupu; Zhang, Jin

XML-based method for standardization of software designing is introduced and analyzed and successfully applied to renovating the hardware and software of the digital clock at Urumqi Astronomical Station. Basic strategy for eliciting time information from the new digital clock of FT206 in the antenna control program is introduced. By FT206, the need to compute how many centuries passed since a certain day with sophisticated formulas is eliminated and it is no longer necessary to set right UT time for the computer holding control over antenna because the information about year, month, day are all deduced from Julian day dwelling in FT206, rather than from computer time. With XML-based method and standard for software designing, various existing designing methods are unified, communications and collaborations between developers are facilitated, and thus Internet-based mode of developing software becomes possible. The trend of development of XML-based designing method is predicted.

Effects of high-fat and high-carbohydrate diets on fat and carbohydrate oxidation and plasma metabolites in healthy cats.

PubMed

Gooding, M A; Flickinger, E A; Atkinson, J L; Duncan, I J H; Shoveller, A K

2014-06-01

High-fat (HF) or high-carbohydrate (HC) diets (30% fat, 18.9% carbohydrate; HF and 10% fat, 46.3% carbohydrate; HC) and lengths of adaptation were investigated in cats (Felis catus; 10 ± 2 months, 3.6 ± 0.3 kg). Cats randomly received each treatment for 14 days in a crossover design with a 14-day washout period between each diet. Three 22-h indirect calorimetry studies were conducted after acute (day 0), semichronic (day 4) and chronic (day 13) dietary exposure. Blood samples were collected after a 24-h fast on days 1, 5 and 14. When cats consumed the HC and HF diet, oxidation of the restricted nutrient exceeded intake while oxidation of the nutrient in excess matched intake. Mean max energy expenditure (EE) of cats consuming the HF and HC diet were 107 and 102 kcal/kg(0.67)/day and occurred at a mean of 4 and 12 h post-feeding respectively. Maximal fat (0.90 g/h) and carbohydrate (carbohydrate; 1.42 g/h) oxidation were attained at 26 min and 10.4 h post-feeding respectively. The changes observed in macronutrient oxidation and EE suggest that cats adapt whole-body nutrient metabolism in response to changes in dietary macronutrient content, but may require longer than 14 day to adapt to a macronutrient that is present at a lower concentration in the diet. Journal of Animal Physiology and Animal Nutrition © 2013 Blackwell Verlag GmbH.

Neuroprotective Activity of Curcumin in Combination with Piperine against Quinolinic Acid Induced Neurodegeneration in Rats.

PubMed

Singh, Shamsher; Kumar, Puneet

2016-01-01

Quinolinic acid (QA) is an excitotoxin that induces Huntington's-like symptoms in animals and humans. Curcumin (CMN) is a well-known antioxidant but the major problem is its bioavailability. Therefore, the present study was designed to investigate the effect of CMN in the presence of piperine against QA-induced excitotoxic cell death in rats. QA was administered intrastriatally at a dose of 200 nmol/2 µl saline, bilaterally. CMN (25 and 50 mg/kg/day, p.o.) and combination of CMN (25 mg/kg/day, p.o.) and with piperine (2.5 mg/kg/day, p.o.) was administered daily for the next 21 days. Body weight and behavioral parameters were observed on 1st, 7th, 14th and 21st day. On the 22nd day, animals were sacrificed and striatum was isolated for biochemical (LPO, nitrite and GSH), neuroinflammatory (interleukin (IL)-1β, IL-6 and TNF-α) and neurochemical (dopamine, norepinephrine, GABA, glutamate, 5-HT, 3,4-dihydroxyphenylacetic acid and homovanillic acid) estimation. CMN treatment showed beneficial effect against QA-induced motor deficit, biochemical and neurochemical abnormalities in rats. Combination of piperine (2.5 mg/kg/day, p.o.) with CMN (25 mg/kg/day, p.o.) significantly enhanced its protective effect as compared to treatment with CMN alone. This study has revealed that the combination of CMN and piperine showed strong antioxidant and protective effect against QA-induced behavioral and neurological alteration in rats. © 2016 S. Karger AG, Basel.

76 FR 25529 - Loyalty Day, 2011

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-05

... Day, 2011 By the President of the United States of America A Proclamation When our Nation's Founders... devotion on a Nation that reflects its people's highest moral aspirations. On this day, we celebrate our... amended, has designated May 1 of each year as ``Loyalty Day.'' On this day, let us reaffirm our allegiance...

Family Day Care Training Curriculum (Lao).

ERIC Educational Resources Information Center

Nakatsu, Gail

California's Family Day Care Training Program was designed to recruit and train, in 7 weeks, Lao, Vietnamese, and Chinese refugees to establish their own state-licensed, family day care homes. Topics in the program's curriculum include an introduction to family day care, state licenses for family day care, state licensing requirements for family…

Family Day Care Training Curriculum.

ERIC Educational Resources Information Center

Nakatsu, Gail

California's Family Day Care Training Program was designed to recruit and train in 7 weeks, Lao, Vietnamese, and Chinese refugees to establish their own state-licensed, family day care homes. Topics in the program's curriculum include an introduction to family day care, state licenses for family day care, state licensing requirements for family…

Communicating Navigation Data Inside the Cassini-Huygens Project: Visualizations and Tools

NASA Technical Reports Server (NTRS)

Wagner, Sean V.; Gist, Emily M.; Goodson, Troy D.; Hahn, Yungsun; Stumpf, Paul W.; Williams, Powtawche N.

2008-01-01

The Cassini-Huygens Saturn tour poses an interesting navigation challenge. From July 2004 through June 2008, the Cassini orbiter performed 112 of 161 planned maneuvers. This demanding schedule, where maneuvers are often separated by just a few days, motivated the development of maneuver design/analysis automation software tools. Besides generating maneuver designs and presentations, these tools are the mechanism to producing other types of navigation information; information used to facilitate operational decisions on such issues as maneuver cancellation and alternate maneuver strategies. This paper will discuss the navigation data that are communicated inside the Cassini-Huygens Project, as well as the maneuver software tools behind the processing of the data.

Phase A conceptual design study of the Atmospheric, Magnetospheric and Plasmas in Space (AMPS) payload

NASA Technical Reports Server (NTRS)

1974-01-01

The 12 month Phase A Conceptual Design Study of the Atmospheric, Magnetospheric and Plasmas in Space (AMPS) payload performed within the Program Development Directorate of the Marshall Space Flight Center is presented. The AMPS payload makes use of the Spacelab pressurized module and pallet, is launched by the space shuttle, and will have initial flight durations of 7 days. Scientific instruments including particle accelerators, high power transmitters, optical instruments, and chemical release devices are mounted externally on the Spacelab pallet and are controlled by the experimenters from within the pressurized module. The capability of real-time scientist interaction on-orbit with the experiment is a major characteristic of AMPS.

Solar process water heat for the IRIS images custom color photo lab

NASA Technical Reports Server (NTRS)

1980-01-01

The solar facility located at a custom photo laboratory in Mill Valley, California is described. It was designed to provide 59 percent of the hot water requirements for developing photographic film and domestic hot water use. The design load is to provide 6 gallons of hot water per minute for 8 hours per working day at 100 F. It has 640 square feet of flat plate collectors and 360 gallons of hot water storage. The auxillary back up system is a conventional gas-fired water heater. Site and building description, subsystem description, as-built drawings, cost breakdown and analysis, performance analysis, lessons learned, and the operation and maintenance manual are presented.

The use of fair-weather cases from the ACT-America Summer 2016 field campaign to better constrain regional biogenic CO2 surface fluxes

NASA Astrophysics Data System (ADS)

Gaudet, B. J.; Davis, K. J.; DiGangi, J. P.; Feng, S.; Hoffman, K.; Jacobson, A. R.; Lauvaux, T.; McGill, M. J.; Miles, N.; Pal, S.; Pauly, R.; Richardson, S.

2017-12-01

The Atmospheric Carbon and Transport - America (ACT-America) study is a multi-year NASA-funded project designed to increase our understanding of regional-scale greenhouse gas (GHG) fluxes over North America through aircraft, satellite, and tower-based observations. This is being accomplished through a series of field campaigns that cover three focus regions (Mid-Atlantic, Gulf Coast, and Midwest), and all four seasons (summer, winter, fall, and spring), as well as a variety of meteorological conditions. While constraints on GHG fluxes can be derived on the global scale (through remote-site concentration measurements and global flux inversion models) and the local scale (through eddy-covariance flux tower measurements), observational constraints on the intermediate scales are not as readily available. Biogenic CO2 fluxes are particularly challenging because of their strong seasonal and diurnal cycles and large spatial variability. During the summer 2016 ACT field campaign, fair weather days were targeted for special flight patterns designed to estimate surface fluxes at scales on the order of 105 km2 using a modified mass-balance approach. For some onshore flow cases in the Gulf Coast, atmospheric boundary layer (ABL) flight transects were performed both inland and offshore when it could be reasonably inferred that the homogeneous Gulf air provided the background GHG field for the inland transect. On other days, two-day flight sequences were performed, where the second-day location of the flight patterns was designed to encompass the air mass that was sampled on the first day. With these flight patterns, the average regional flux can be estimated from the ABL CO2 concentration change. Direct measurements of ABL depth from both aircraft profiles and high-resolution airborne lidar will be used, while winds and free-tropospheric CO2 can be determined from model output and in situ aircraft observations. Here we will present examples of this flux estimation for both Gulf-inflow and two-day fair-weather pattern cases from the summer 2016 ACT-America field campaign. We will also examine processes that lead to uncertainty in these estimates, and quantify these uncertainties. Implications for the ability of this regional flux determination to constrain the existing suite of GHG flux estimates will be discussed.

CVT/GPL phase 3 integrated testing

NASA Technical Reports Server (NTRS)

Shurney, R. E.; Cantrell, E.; Maybee, G.; Schmitt, S.

1975-01-01

The hardware for 20 candidate shuttle program life sciences experiments was installed in the GPL and experiments were conducted during a 5-day simulated mission. The experiments involved humans, primates, rats, chickens, and marigold plants. All experiments were completed to the satisfaction of the experimenters. In addition to the scientific data gathered for each experiment, information was obtained concerning experiment hardware design and integration, experiment procedures, GPL support systems, and test operations. The results of the integrated tests are presented.

Development and Implementation of a Model Training Program to Assist Special Educators, Parks and Resource Management Personnel and Parents to Cooperatively Plan and Conduct Outdoor/Environmental Education Programs for Handicapped Children and Youth. Final Report.

ERIC Educational Resources Information Center

Vinton, Dennis A.; Zachmeyer, Richard F.

This final report presents a description of a 3-year project to develop and implement a model training program (for special education personnel, park and resource management personnel, and parents of disabled children) designed to promote outdoor environmental education for disabled children. The project conducted 22 training workshops (2-5 days)…

Aircraft rate-of-climb indicators

NASA Technical Reports Server (NTRS)

Johnson, Daniel P

1939-01-01

The theory of the rate-of-climb indicator is developed in a form adapted for application to the instrument in its present-day form. Compensations for altitude, temperature, and rate of change of temperature are discussed from the designer's standpoint on the basis of this theory. Certain dynamic effects, including instrument lag, and the use of the rate-of-climb indicator as a statoscope are also considered. Modern instruments are described. A laboratory test procedure is outlined and test results are given.

Transcatheter Mitral Valve Replacement for Native and Failed Bioprosthetic Mitral Valves

PubMed Central

Sarkar, Kunal; Reardon, Michael J.; Little, Stephen H.; Barker, Colin M.; Kleiman, Neal S.

2017-01-01

Transcatheter mitral valve replacement (TMVR) is a novel approach for treatment of severe mitral regurgitation. A number of TMVR devices are currently undergoing feasibility trials using both transseptal and transapical routes for device delivery. Overall experience worldwide is limited to fewer than 200 cases. At present, the 30-day mortality exceeds 30% and is attributable to both patient- and device-related factors. TMVR has been successfully used to treat patients with degenerative mitral stenosis (DMS) as well as failed mitral bioprosthesis and mitral repair using transcatheter mitral valve-in-valve (TMViV)/valve-in-ring (ViR) repair. These patients are currently treated with devices designed for transcatheter aortic valve replacement. Multicenter registries have been initiated to collect outcomes data on patients currently undergoing TMViV/ViR and TMVR for DMS and have confirmed the feasibility of TMVR in these patients. However, the high periprocedural and 30-day event rates underscore the need for further improvements in device design and multicenter randomized studies to delineate the role of these technologies in patients with mitral valve disease. PMID:29743999

An autonomous, automated and mobile device to concurrently assess several cognitive functions in group-living non-human primates.

PubMed

Fizet, Jonas; Rimele, Adam; Pebayle, Thierry; Cassel, Jean-Christophe; Kelche, Christian; Meunier, Hélène

2017-11-01

Research methods in cognitive neuroscience using non-human primates have undergone notable changes over the last decades. Recently, several research groups have described freely accessible devices equipped with a touchscreen interface. Two characteristics of such systems are of particular interest: some apparatuses include automated identification of subjects, while others are mobile. Here, we designed, tested and validated an experimental system that, for the first time, combine automatization and mobility. Moreover, our system allows autonomous learning and testing of cognitive performance in group-living subjects, including follow-up assessments. The mobile apparatus is designed to be available 24h a day, 7days a week, in a typical confined primate breeding and housing facility. Here we present as proof of concept, the results of two pilot studies. We report that rhesus macaques (Macaca mulatta) learned the tasks rapidly and achieved high-level of stable performance. Approaches of this kind should be developed for future pharmacological and biomedical studies in non-human primates. Copyright © 2017 Elsevier Inc. All rights reserved.

Science Results and Lessons Learned from CubeSat: Colorado Space Weather Experiment (CSSWE)

NASA Astrophysics Data System (ADS)

Li, Xinlin

The Relativistic Electron and Proton Telescope integrated little experiment (REPTile) is a loaded-disc collimated solid-state particle telescope, designed, built, tested, and operated by a team of students at the University of Colorado. It is the only science payload onboard the Colorado Student Space Weather Experiment (CSSWE), a 3U CubeSat (10cm x 10cm x 30cm) launched into a low-Earth, 480km x 780km, and highly inclined (65 deg) orbit on 13 September 2012. REPTile measures differential fluxes of 0.58 to >3.8 MeV electrons and 9-40 MeV protons. These measurements, by themselves and in conjunction with other larger missions, are critical to understand the dynamics of these energetic particles. Miniaturizing a power- and mass-hungry particle telescope to return clean measurements from a CubeSat platform is challenging. To overcome these challenges, REPTile underwent a rigorous design and testing phase. Despite the limitations inherent with CubeSats, REPTile to date (still in operation) has returned more than 300 days of valuable science data, more than tripling its nominal mission lifetime of 90 days. The data are clean, as REPTile is able to clearly distinguish between particle species. Important science results using REPTile data, some of which have been published in peer-reviewed journals, will be presented in this presentation.

KENNEDY SPACE CENTER, FLA. - After arriving at Launch Complex 17-A, Cape Canaveral Air Force Station, the second half of the fairing for the Mars Exploration Rover 2 (MER-2/MER-A) is lifted off its transporter. The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - After arriving at Launch Complex 17-A, Cape Canaveral Air Force Station, the second half of the fairing for the Mars Exploration Rover 2 (MER-2/MER-A) is lifted off its transporter. The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

KENNEDY SPACE CENTER, FLA. - At Launch Complex 17-A, Cape Canaveral Air Force Station, the first half of the fairing for the Mars Exploration Rover 2 (MER-2/MER-A) is lifted up the launch tower. The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - At Launch Complex 17-A, Cape Canaveral Air Force Station, the first half of the fairing for the Mars Exploration Rover 2 (MER-2/MER-A) is lifted up the launch tower. The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

KENNEDY SPACE CENTER, FLA. - At Launch Complex 17-A, Cape Canaveral Air Force Station, the first half of the fairing for the Mars Exploration Rover 2 (MER-2/MER-A) reaches the top of the launch tower. The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - At Launch Complex 17-A, Cape Canaveral Air Force Station, the first half of the fairing for the Mars Exploration Rover 2 (MER-2/MER-A) reaches the top of the launch tower. The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

KENNEDY SPACE CENTER, FLA. - At Launch Complex 17-A, Cape Canaveral Air Force Station, the first half of the fairing for the Mars Exploration Rover 2 (MER-2/MER-A) is lifted off the transporter. The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - At Launch Complex 17-A, Cape Canaveral Air Force Station, the first half of the fairing for the Mars Exploration Rover 2 (MER-2/MER-A) is lifted off the transporter. The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5.

KENNEDY SPACE CENTER, FLA. - At Launch Complex 17-A, Cape Canaveral Air Force Station, the first half of the fairing for the Mars Exploration Rover 2 (MER-2/MER-A) is moved inside the launch tower. The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5..

NASA Image and Video Library

2003-04-30

KENNEDY SPACE CENTER, FLA. - At Launch Complex 17-A, Cape Canaveral Air Force Station, the first half of the fairing for the Mars Exploration Rover 2 (MER-2/MER-A) is moved inside the launch tower. The fairing will be installed around the payload for protection during launch. The MER Mission consists of two identical rovers designed to cover roughly 110 yards each Martian day over various terrain. Each rover will carry five scientific instruments that will allow it to search for evidence of liquid water that may have been present in the planet's past. Identical to each other, the rovers will land at different regions of Mars. Launch date for MER-A is scheduled for June 5..

FLIT: Flowing LIquid metal Torus

NASA Astrophysics Data System (ADS)

Kolemen, Egemen; Majeski, Richard; Maingi, Rajesh; Hvasta, Michael

2017-10-01

The design and construction of FLIT, Flowing LIquid Torus, at PPPL is presented. FLIT focuses on a liquid metal divertor system suitable for implementation and testing in present-day fusion systems, such as NSTX-U. It is designed as a proof-of-concept fast-flowing liquid metal divertor that can handle heat flux of 10 MW/m2 without an additional cooling system. The 72 cm wide by 107 cm tall torus system consisting of 12 rectangular coils that give 1 Tesla magnetic field in the center and it can operate for greater than 10 seconds at this field. Initially, 30 gallons Galinstan (Ga-In-Sn) will be recirculated using 6 jxB pumps and flow velocities of up to 10 m/s will be achieved on the fully annular divertor plate. FLIT is designed as a flexible machine that will allow experimental testing of various liquid metal injection techniques, study of flow instabilities, and their control in order to prove the feasibility of liquid metal divertor concept for fusion reactors. FLIT: Flowing LIquid metal Torus. This work is supported by the US DOE Contract No. DE-AC02-09CH11466.

Overview of experiment design and comparison of models participating in phase 1 of the SPARC Quasi-Biennial Oscillation initiative (QBOi)

NASA Astrophysics Data System (ADS)

Butchart, Neal; Anstey, James A.; Hamilton, Kevin; Osprey, Scott; McLandress, Charles; Bushell, Andrew C.; Kawatani, Yoshio; Kim, Young-Ha; Lott, Francois; Scinocca, John; Stockdale, Timothy N.; Andrews, Martin; Bellprat, Omar; Braesicke, Peter; Cagnazzo, Chiara; Chen, Chih-Chieh; Chun, Hye-Yeong; Dobrynin, Mikhail; Garcia, Rolando R.; Garcia-Serrano, Javier; Gray, Lesley J.; Holt, Laura; Kerzenmacher, Tobias; Naoe, Hiroaki; Pohlmann, Holger; Richter, Jadwiga H.; Scaife, Adam A.; Schenzinger, Verena; Serva, Federico; Versick, Stefan; Watanabe, Shingo; Yoshida, Kohei; Yukimoto, Seiji

2018-03-01

The Stratosphere-troposphere Processes And their Role in Climate (SPARC) Quasi-Biennial Oscillation initiative (QBOi) aims to improve the fidelity of tropical stratospheric variability in general circulation and Earth system models by conducting coordinated numerical experiments and analysis. In the equatorial stratosphere, the QBO is the most conspicuous mode of variability. Five coordinated experiments have therefore been designed to (i) evaluate and compare the verisimilitude of modelled QBOs under present-day conditions, (ii) identify robustness (or alternatively the spread and uncertainty) in the simulated QBO response to commonly imposed changes in model climate forcings (e.g. a doubling of CO2 amounts), and (iii) examine model dependence of QBO predictability. This paper documents these experiments and the recommended output diagnostics. The rationale behind the experimental design and choice of diagnostics is presented. To facilitate scientific interpretation of the results in other planned QBOi studies, consistent descriptions of the models performing each experiment set are given, with those aspects particularly relevant for simulating the QBO tabulated for easy comparison.

Physical Science Day: Design, Implementation, and Assessment

ERIC Educational Resources Information Center

Zeng, Liang; Cunningham, Mark A.; Tidrow, Steven C.; Smith, K. Christopher; Contreras, Jerry

2016-01-01

Physical Science Day at The University of Texas--Pan American (UTPA), in collaboration with the Edinburg Consolidated Independent School District, has been designed, developed and implemented to address an identified fundamental shortcoming in our educational process within this primarily (90+%) Hispanic serving border region. Physical Science Day…

Solar Water-Heater Design Package

NASA Technical Reports Server (NTRS)

1982-01-01

Information on a solar domestic-hot water heater is contained in 146 page design package. System consists of solar collector, storage tanks, automatic control circuitry and auxiliary heater. Data-acquisition equipment at sites monitors day-by-day performance. Includes performance specifications, schematics, solar-collector drawings and drawings of control parts.

Par for the Course: Students Design Their Miniature Golf Course Sculptures while Considering Functional, Technical, and Communication Elements

ERIC Educational Resources Information Center

Vassil, Darlene

2005-01-01

Designing an eighteen-hole miniature-golf course is not the typical end-of-the-year art project, but at Winfield School it's "par for the course." Students anxiously count the days to the first day of miniature golf, courtesy of the sixth-grade art classes. The design and production of the miniature gold course serves as a great motivator and…

Novel contact hole reticle design for enhanced lithography process window in IC manufacturing

NASA Astrophysics Data System (ADS)

Chang, Chung-Hsing

2005-01-01

For 90nm node generation, 65nm, and beyond, dark field mask types such as contact-hole, via, and trench patterns that all are very challenging to print with satisfactory process windows for day-to-day lithography manufacturing. Resolution enhancement technology (RET) masks together with ArF high numerical aperture (NA) scanners have been recognized as the inevitable choice of method for 65nm node manufacturing. Among RET mask types, the alternating phase shifting mask (AltPSM) is one of the well-known strong enhancement techniques. However AltPSM can have a very strong optical proximity effect that comes with the use of small on-axis illumination sigma setting. For very dense contact features, it may be possible for AltPSM to overcome the phase conflict by limiting the mask design rules. But it is not feasible to resolve the inherent phase conflict for the semi-dense, semi-isolated and isolated contact areas. Hence the adoption of this strong enhancement technique for dark filed mask types in today"s IC manufacturing has been very limited. In this paper, we present a novel yet a very powerful design method to achieve contact and via masks printing for 90nm, 65nm, and beyond. We name our new mask design as: Novel Improved Contact-hole pattern Exposure PSM (NICE PSM) with off-axis illumination, such as QUASAR. This RET masks design can enhance the process window of isolated, semi-isolated contact hole and via hole patterns. The main concepts of NICE PSM with QUASAR off-axis illumination are analogous to the Super-FLEX pupil filter technology.

Departing from PowerPoint default mode: Applying Mayer's multimedia principles for enhanced learning of parasitology.

PubMed

Nagmoti, Jyoti Mahantesh

2017-01-01

PowerPoint (PPT™) presentation has become an integral part of day-to-day teaching in medicine. Most often, PPT™ is used in its default mode which in fact, is known to cause boredom and ineffective learning. Research has shown improved short-term memory by applying multimedia principles for designing and delivering lectures. However, such evidence in medical education is scarce. Therefore, we attempted to evaluate the effect of multimedia principles on enhanced learning of parasitology. Second-year medical students received a series of lectures, half of the lectures used traditionally designed PPT™ and the rest used slides designed by Mayer's multimedia principles. Students answered pre and post-tests at the end of each lecture (test-I) and an essay test after six months (test-II) which assessed their short and long term knowledge retention respectively. Students' feedback on quality and content of lectures were collected. Statistically significant difference was found between post test scores of traditional and modified lectures (P = 0.019) indicating, improved short-term memory after modified lectures. Similarly, students scored better in test II on the contents learnt through modified lectures indicating, enhanced comprehension and improved long-term memory (P < 0.001). Many students appreciated learning through multimedia designed PPT™ and suggested for their continued use. It is time to depart from default PPT™ and adopt multimedia principles to enhance comprehension and improve short and long term knowledge retention. Further, medical educators may be trained and encouraged to apply multimedia principles for designing and delivering effective lectures.

Effects of cholesterol and cAMP on progesterone production in cultured luteal cells isolated from pseudopregnant cat ovaries.

PubMed

Arikan, Sevket; Yigit, Ayse Arzu

2009-10-01

The present study was designed to incubate luteal cells isolated from pseudopregnant cats and to investigate the effects of cholesterol and cAMP on luteal progesterone production. Corpora lutea were collected from the cats on days 10 and 15 of pseudopregnancy. Luteal cells were isolated from the ovaries by collagenase digestion. Steroidogenic luteal cells were stained for 3beta-hydroxysteroid dehydrogenase (3beta-HSD) activity. Cells (2 x 10(4)) staining positive for 3beta-HSD were cultured for up to 7 days. The cells were treated with 22(R)-hydroxycholesterol (22R-HC) and dibutyryl cyclic AMP (dbcAMP) on days 1, 3 and 7. Treatment of cells with 22R-HC resulted in a dose-dependent increase (p<0.001) in progesterone production. When 22R-HC was used at a concentration of 10 microg/ml, it resulted in 2.7- and 5.1-fold increases in progesterone production on days 3 and 5, respectively. When the dose was doubled (20 microg/ml), treated cells produced four times more progesterone on days 3 and 7, and three times more on day 5. By day 7, progesterone production increased up to 9.1 times more than the control. Incubation of cells with both concentrations of dbcAMP (0.1 mM and 1 mM) resulted in significant stimulations of progesterone on days 5 and 7 (p<0.001). However, on day 3, only higher doses of dbcAMP (1 mM) resulted in significant stimulation (p<0.05). Progesterone production was increased up to 2- and 2.9-fold of the control when cells were treated with lower concentration of dbcAMP (0.1 mM) on days 5 and 7, respectively. Incubation of cells with 1 mM concentrations of dbcAMP induced a 3.2-fold increase on day 5 and a 5-fold increase on day 7. In conclusion, a successful incubation was performed for long-life culturing of luteal cells collected from pseudopregnant cats. The method works well and allows for optimal growth and development of cells in the culture. The present study also demonstrated that incubating cat luteal cells with 22R-HC and dbcAMP induces a significant increase in luteal progesterone synthesis.

Preliminary Tests of Blowers of Three Designs Operating in Conjunction with a Wing-Duct Cooling System for Radial Engines, Special Report

NASA Technical Reports Server (NTRS)

Biermann, David; Valentine, E. Floyd

1939-01-01

This paper is one of several dealing with methods intended to reduce the drag of present-day radial engine installations and improve the cooling at zero and low air speeds, The present paper describes model wind-tunnel tests of blowers of three designs tested in conjunction with a wing-nacelle combination. The principle of operation involved consists of drawing cooling air into ducts located in the wing root at the point of maximum slipstream velocity, passing the air through the engine baffles from rear to front, and exhausting the air through an annular slot located between the propeller and the engine with the aid of a blower mounted on the spinner. The test apparatus consisted essentially of a stub wing having a 5-foot chord and a 15-foot span, an engine nacelle of 20 inches diameter enclosing a 25-horsepower electric motor, and three blowers mounted on propeller spinners. Two of the blowers utilize centrifugal force while the other uses the lift from airfoils to force the air out radially through the exit slot. Maximum efficiencies of over 70 percent were obtained for the system as a whole. Pressures were measured over the entire flight range which were in excess of those necessary to cool present-day engines, The results indicated that blowers mounted on propeller spinners could be built sufficiently powerful and efficient to warrant their use as the only, or chief, means of forcing air through the cooling system, so that cooling would be independent of the speed of the airplane.

Probing vocal fold fibroblast response to hyaluronan in 3D contexts.

PubMed

Munoz-Pinto, Dany J; Jimenez-Vergara, Andrea Carolina; Gelves, L Marcela; McMahon, Rebecca E; Guiza-Arguello, Viviana; Hahn, Mariah S

2009-11-01

A number of treatments are being investigated for vocal fold (VF) scar, including designer implants. The aim of the present study was to validate a 3D model system for probing the effects of various bioactive moieties on VF fibroblast (VFF) behavior toward rational implant design. We selected poly(ethylene glycol) diacrylate (PEGDA) hydrogels as our base-scaffold due to their broadly tunable material properties. However, since cells encapsulated in PEGDA hydrogels are generally forced to take on rounded/stellate morphologies, validation of PEGDA gels as a 3D VFF model system required that the present work directly parallel previous studies involving more permissive scaffolds. We therefore chose to focus on hyaluronan (HA), a polysaccharide that has been a particular focus of the VF community. Toward this end, porcine VFFs were encapsulated in PEGDA hydrogels containing consistent levels of high Mw HA (HA(HMW)), intermediate Mw HA (HA(IMW)), or the control polysaccharide, alginate, and cultured for 7 and 21 days. HA(HMW) promoted sustained increases in active ERK1/2 relative to HA(IMW). Furthermore, VFFs in HA(IMW) gels displayed a more myofibroblast-like phenotype, higher elastin production, and greater protein kinase C (PkC) levels at day 21 than VFFs in HA(HMW) and alginate gels. The present results are in agreement with a previous 3D study of VFF responses to HA(IMW) relative to alginate in collagen-based scaffolds permissive of cell elongation, indicating that PEGDA hydrogels may serve as an effective 3D model system for probing at least certain aspects of VFF behavior. Copyright 2009 Wiley Periodicals, Inc.

Characterization of Tifton 85 bermudagrass haylage with different layers of polyethylene film and storage time.

PubMed

Nath, Caroline Daiane; Neres, Marcela Abbado; Scheidt, Kácia Carine; Bersot, Luciano Dos Santos; Sunahara, Samantha Mariana Monteiro; Sarto, Jaqueline Rocha Wobeto; Stangarlin, José Renato; Gomes, Simone Damasceno; Sereno, Mallu Jagnow; Perin, Ana Paula

2018-03-02

The objective was to characterize the fermentative and microbiological profile of Tifton 85 bermudagrass haylage with different layers of polyethylene film and storage time. The experimental design consisted of a randomized block design with four and six wrapping layers (100 and 150 microns in total. respectively) allocated in the main plots, through repeated measures analysis (30, 60, and 90 days of storage) with four replicates. The storage time and number of wrapping layers did not show changes in the population of Clostridium and lactic acid bacteria. A decrease was observed in the enterobacteria population with an increase in the storage period in the two wrapping layers studied. Upon opening of the haylage at 30 days, the population of Bacillus was lower in haylages made with six layers of wrapping (3.63 log colony forming units (CFU) g-1). No growth of Listeria sp. or Salmonella sp. was observed during the experimental period. The fungal genera with greater occurrence were Penicillium sp. and Fusarium sp. The following mycotoxins were not detected: ochratoxin A, fumonisins, and zearalenone. Relative to the organic butyric, propionic, and acetic acids, the haylages presented a low concentration of lactic acid; this may have prevented a drop in the pH, which was high when the silos were opened (5.4). The levels of ammoniacal nitrogen and soluble carbohydrates presented no variation among the number of wrapping layers, with an overall average of 35.55 and 38.04 g kg-1. Tifton 85 bermudagrass haylage wrapped with four and six layers presented adequate fermentation and microbiological characteristics in the evaluated periods.

Daily Weather and Children's Physical Activity Patterns.

PubMed

Remmers, Teun; Thijs, Carel; Timperio, Anna; Salmon, J O; Veitch, Jenny; Kremers, Stef P J; Ridgers, Nicola D

2017-05-01

Understanding how the weather affects physical activity (PA) may help in the design, analysis, and interpretation of future studies, especially when investigating PA across diverse meteorological settings and with long follow-up periods. The present longitudinal study first aims to examine the influence of daily weather elements on intraindividual PA patterns among primary school children across four seasons, reflecting day-to-day variation within each season. Second, we investigate whether the influence of weather elements differs by day of the week (weekdays vs weekends), gender, age, and body mass index. PA data were collected by ActiGraph accelerometers for 1 wk in each of four school terms that reflect each season in southeast Australia. PA data from 307 children (age range 8.7-12.8 yr) were matched to daily meteorological variables obtained from the Australian Government's Bureau of Meteorology (maximum temperature, relative humidity, solar radiation, day length, and rainfall). Daily PA patterns and their association with weather elements were analyzed using multilevel linear mixed models. Temperature was the strongest predictor of moderate and vigorous PA, followed by solar radiation and humidity. The relation with temperature was curvilinear, showing optimum PA levels at temperatures between 20°C and 22°C. Associations between weather elements on PA did not differ by gender, child's age, or body mass index. This novel study focused on the influence of weather elements on intraindividual PA patterns in children. As weather influences cannot be controlled, knowledge of its effect on individual PA patterns may help in the design of future studies, interpretation of their results, and translation into PA promotion.

Contact events in rugby union and their propensity to cause injury

PubMed Central

Fuller, Colin W; Brooks, John H M; Cancea, Rebecca J; Hall, John; Kemp, Simon P T

2007-01-01

Objective The objective of this study was to determine the incidence of contact events in professional rugby union matches and to assess their propensity to cause injury. Design The study was a two‐season (2003/2004 and 2005/2006) prospective cohort design. It included 645 professional rugby union players from 13 English Premiership rugby union clubs. The main outcome measures were: incidence of match contact events (events per game); incidence (injuries per 1000 player‐hours and per 1000 contact events), risk (days lost per 1000 player‐hours and per 1000 contact events) and diagnosis of injury; referee's decision. Risk factors were player–player contact, position on pitch and period of play. Results Tackles (221.0 events/game) and rucks (142.5 events/game) were the most common events and mauls (13.6%) and scrums (12.6%) the most penalised. Tackles (701.6 days/1000 player‐hours) were responsible for the greatest loss of time but scrums (213.2 days lost/1000 events) and collisions (199.8 days lost/1000 events) presented the highest risk per event. Conclusions Tackles were the game event responsible for the highest number of injuries and the greatest loss of time in rugby union because they were by far the most common contact event. Collisions were 70% more likely to result in an injury than a tackle and scrums carried a 60% greater risk of injury than a tackle. The relative propensities for contact events to cause injury were rated as: lineout – very low; ruck – low; maul and tackle – average; collision and scrum – high. PMID:17513332

Advancing Care Within an Adult Mental Health Day Hospital: Program Re-Design and Evaluation.

PubMed

Taube-Schiff, Marlene; Mehak, Adrienne; Marangos, Sandy; Kalim, Anastasia; Ungar, Thomas

2017-11-13

Day hospital mental health programs provide alternate care to individuals of high acuity that do not require an inpatient psychiatric stay. Ensuring provision of best practice within these programs is essential for patient stabilization and recovery. However, there is scant literature to review when creating such a program. This paper provides an overview of the steps an acute care hospital took when designing and implementing new programming within a day hospital program. Qualitative data was collected following initial program rollout. This data helped to inform the ongoing modification of groups offered, group scheduling and content, as well as ensuring patient satisfaction and adequate skill delivery during the rollout period and beyond. The goal of this paper is to inform health service delivery for other programs when attempting to build or re-design a day hospital program.

Thermal Optimization of an On-Orbit Long Duration Cryogenic Propellant Depot

NASA Technical Reports Server (NTRS)

Honour, Ryan; Kwas, Robert; O'Neil, Gary; Kutter, Gary

2012-01-01

A Cryogenic Propellant Depot (CPD) operating in Low Earth Orbit (LEO) could provide many near term benefits to NASA's space exploration efforts. These benefits include elongation/extension of spacecraft missions and requirement reduction of launch vehicle up-mass. Some of the challenges include controlling cryogenic propellant evaporation and managing the high costs and long schedules associated with the new development of spacecraft hardware. This paper describes a conceptual CPD design that is thermally optimized to achieve extremely low propellant boil-off rates. The CPD design is based on existing launch vehicle architecture, and its thermal optimization is achieved using current passive thermal control technology. Results from an integrated thermal model are presented showing that this conceptual CPD design can achieve propellant boil-off rates well under 0.05% per day, even when subjected to the LEO thermal environment.

System Engineering the Space Infrared Interferometric Telescope (SPIRIT)

NASA Technical Reports Server (NTRS)

Hyde, Tristram T.; Leisawitz, David T.; Rinehart, Stephen

2007-01-01

The Space Infrared Interferometric Telescope (SPIRIT) was designed to accomplish three scientific objectives: (1) learn how planetary systems form from protostellar disks and how they acquire their inhomogeneous chemical composition; (2) characterize the family of extrasolar planetary systems by imaging the structure in debris disks to understand how and where planets of different types form; and (3) learn how high-redshift galaxies formed and merged to form the present-day population of galaxies. SPIRIT will accomplish these objectives through infrared observations with a two aperture interferometric instrument. This paper gives an overview of SPIRIT design and operation, and how the three design cycle concept study was completed. The error budget for several key performance values allocates tolerances to all contributing factors, and a performance model of the spacecraft plus instrument system demonstrates meeting those allocations with margin.

Thermal Optimization and Assessment of a Long Duration Cryogenic Propellant Depot

NASA Technical Reports Server (NTRS)

Honour, Ryan; Kwas, Robert; O'Neil, Gary; Kutter, Bernard

2012-01-01

A Cryogenic Propellant Depot (CPD) operating in Low Earth Orbit (LEO) could provide many near term benefits to NASA space exploration efforts. These benefits include elongation/extension of spacecraft missions and reduction of launch vehicle up-mass requirements. Some of the challenges include controlling cryogenic propellant evaporation and managing the high costs and long schedules associated with new spacecraft hardware development. This paper describes a conceptual CPD design that is thermally optimized to achieve extremely low propellant boil-off rates. The CPD design is based on existing launch vehicle architecture, and its thermal optimization is achieved using current passive thermal control technology. Results from an integrated thermal model are presented showing that this conceptual CPD design can achieve propellant boil-off rates well under 0.05% per day, even when subjected to the LEO thermal environment.

Design of a hip prosthetic tribometer based on salat gait cycle

NASA Astrophysics Data System (ADS)

Towijaya, T.; Ismail, R.; Jamari, J.

2017-01-01

Indonesia is the country with the largest muslim population in the world, most of the inhabitants do salat every day. THR (Total Hip Replacement) patients are prohibited from doing salat in normal gait. It leads to the damage of the hip joint prostheses due to impingement and dislocation.This paper reports the design of a pin-on-ring tribometer which is used to measure and analyze the wear volume and the impingement of hip joint prostheses during salat. The modifications of the femoral head and acetabular cup holder are performed to design the reciprocating motion for the movement of the hip prostheses. The interesting finding of the present research is a new mechanism of linked-bar which leads to the feasibility of the measurement of the wear volume and the impingement for THR patients during salat.

Compact illumination optic with three freeform surfaces for improved beam control.

PubMed

Sorgato, Simone; Mohedano, Rubén; Chaves, Julio; Hernández, Maikel; Blen, José; Grabovičkić, Dejan; Benítez, Pablo; Miñano, Juan Carlos; Thienpont, Hugo; Duerr, Fabian

2017-11-27

Multi-chip and large size LEDs dominate the lighting market in developed countries these days. Nevertheless, a general optical design method to create prescribed intensity patterns for this type of extended sources does not exist. We present a design strategy in which the source and the target pattern are described by means of "edge wavefronts" of the system. The goal is then finding an optic coupling these wavefronts, which in the current work is a monolithic part comprising up to three freeform surfaces calculated with the simultaneous multiple surface (SMS) method. The resulting optic fully controls, for the first time, three freeform wavefronts, one more than previous SMS designs. Simulations with extended LEDs demonstrate improved intensity tailoring capabilities, confirming the effectiveness of our method and suggesting that enhanced performance features can be achieved by controlling additional wavefronts.

Dynamic allocation of same-day requests in multi-physician primary care practices in the presence of prescheduled appointments.

PubMed

Balasubramanian, Hari; Biehl, Sebastian; Dai, Longjie; Muriel, Ana

2014-03-01

Appointments in primary care are of two types: 1) prescheduled appointments, which are booked in advance of a given workday; and 2) same-day appointments, which are booked as calls come during the workday. The challenge for practices is to provide preferred time slots for prescheduled appointments and yet see as many same-day patients as possible during regular work hours. It is also important, to the extent possible, to match same-day patients with their own providers (so as to maximize continuity of care). In this paper, we present a mathematical framework (a stochastic dynamic program) for same-day patient allocation in multi-physician practices in which calls for same-day appointments come in dynamically over a workday. Allocation decisions have to be made in the presence of prescheduled appointments and without complete demand information. The objective is to maximize a weighted measure that includes the number of same-day patients seen during regular work hours as well as the continuity provided to these patients. Our experimental design is motivated by empirical data we collected at a 3-provider family medicine practice in Massachusetts. Our results show that the location of prescheduled appointments - i.e. where in the day these appointments are booked - has a significant impact on the number of same-day patients a practice can see during regular work hours, as well as the continuity the practice is able to provide. We find that a 2-Blocks policy which books prescheduled appointments in two clusters - early morning and early afternoon - works very well. We also provide a simple, easily implementable policy for schedulers to assign incoming same-day requests to appointment slots. Our results show that this policy provides near-optimal same-day assignments in a variety of settings.

Baby-Friendly Practices Minimize Newborn Infants Weight Loss.

PubMed

Procaccini, Diane; Curley, Ann L Cupp; Goldman, Martha

2018-04-01

It is accepted that newborns lose weight in the first few days of life. Baby-Friendly practices that support breastfeeding may affect newborn weight loss. The objective of this study were: 1) To determine whether Baby-Friendly practices are associated with term newborn weight loss day 0-2 in three feeding categories (exclusively breastfed, mixed formula fed and breastfed, and formula fed). 2) To determine whether Baby-Friendly practices increase exclusive breast feeding rates in different ethnic populations. This was a retrospective case-control study. Term newborn birth weight, neonatal weights days 0-2, feeding type, type of birth, and demographic information were collected for 1,000 births for the year before Baby-Friendly designation (2010) and 1,000 in 2013 (after designation). Ultimately 683 in the first group and 518 in the second met the inclusion criteria. Mean weight loss decreased day 0-2 for infants in all feeding types after the initiation of Baby-Friendly practices. There was a statistically significant effect of Baby-Friendly designation on weight loss for day 0-2 in exclusively breastfed infants (p < 0.01) after controlling for birth weight. Exclusive breast feeding increased in all ethnic groups after Baby-Friendly practices were put in place. There was a decrease in mean weight loss day 0-2 regardless of feeding type after Baby-Friendly designation. Exclusive breast feeding increased in the presence of Baby-Friendly practices.

29 CFR 2200.206 - Disclosure of information.

Code of Federal Regulations, 2010 CFR

2010-07-01

... working days after a case is designated for Simplified Proceedings, the Secretary shall provide the employer, free of charge, copies of the narrative (Form OSHA 1-A) and the worksheet (Form OSHA 1-B), or their equivalents. (2) Within 30 calendar days after a case is designated for Simplified Proceedings...

Disrupting reconsolidation of fear memory in humans by a noradrenergic β-blocker.

PubMed

Kindt, Merel; Soeter, Marieke; Sevenster, Dieuwke

2014-12-18

The basic design used in our human fear-conditioning studies on disrupting reconsolidation includes testing over different phases across three consecutive days. On day 1 - the fear acquisition phase, healthy participants are exposed to a series of picture presentations. One picture stimulus (CS1+) is repeatedly paired with an aversive electric stimulus (US), resulting in the acquisition of a fear association, whereas another picture stimulus (CS2-) is never followed by an US. On day 2 - the memory reactivation phase, the participants are re-exposed to the conditioned stimulus without the US (CS1-), which typically triggers a conditioned fear response. After the memory reactivation we administer an oral dose of 40 mg of propranolol HCl, a β-adrenergic receptor antagonist that indirectly targets the protein synthesis required for reconsolidation by inhibiting the noradrenaline-stimulated CREB phosphorylation. On day 3 - the test phase, the participants are again exposed to the unreinforced conditioned stimuli (CS1- and CS2-) in order to measure the fear-reducing effect of the manipulation. This retention test is followed by an extinction procedure and the presentation of situational triggers to test for the return of fear. Potentiation of the eye blink startle reflex is measured as an index for conditioned fear responding. Declarative knowledge of the fear association is measured through online US expectancy ratings during each CS presentation. In contrast to extinction learning, disrupting reconsolidation targets the original fear memory thereby preventing the return of fear. Although the clinical applications are still in their infancy, disrupting reconsolidation of fear memory seems to be a promising new technique with the prospect to persistently dampen the expression of fear memory in patients suffering from anxiety disorders and other psychiatric disorders.

Performance of Subsurface Tube Drainage System in Saline Soils: A Case Study

NASA Astrophysics Data System (ADS)

Pali, A. K.

2015-06-01

In order to improve the saline and water logged soils caused due to groundwater table rise, installation of subsurface drainage system is considered as one of the best remedies. However, the design of the drainage system has to be accurate so that the field performance results conform to the designed results. In this investigation, the field performance of subsurface tube drainage system installed at the study area was evaluated. The performance was evaluated on the basis of comparison of the designed value of water table drop as 30 cm after 2 days of drainage and predicted and field measured hydraulic heads for a consecutive drainage period of 14 days. The investigation revealed that the actual drop of water table after 2 days of drainage was 25 cm, about 17 % less than the designed value of 30 cm after 2 days of drainage. The comparison of hydraulic heads predicted by Van Schilfgaarde equation of unsteady drainage with the field-measured hydraulic heads showed that the deviation of predicted hydraulic heads varied within a range of ±8 % indicating high acceptability of Van Schlifgaarde equation for designing subsurface drainage system in saline and water logged soils resembling to that of the study area.

Microwave landing system autoland system analysis

NASA Technical Reports Server (NTRS)

Feather, J. B.; Craven, B. K.

1991-01-01

The objective was to investigate the ability of present day aircraft equipped with automatic flight control systems to fly advanced Microwave Landing Systems (MLS) approaches. The tactical approach used to achieve this objective included reviewing the design and autoland operation of the MD-80 aircraft, simulating the MLS approaches using a batch computer program, and assessing the performance of the autoland system from computer generated data. The results showed changes were required to present Instrument Landing System (ILS) procedures to accommodate the new MLS curved paths. It was also shown that in some cases, changes to the digital flight guidance systems would be required so that an autoland could be performed.

Passive Fully Polarimetric W-Band Millimeter-Wave Imaging

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bernacki, Bruce E.; Kelly, James F.; Sheen, David M.

2012-04-01

We present the theory, design, and experimental results obtained from a scanning passive W-band fully polarimetric imager. Passive millimeter-wave imaging offers persistent day/nighttime imaging and the ability to penetrate dust, clouds and other obscurants, including clothing and dry soil. The single-pixel scanning imager includes both far-field and near-field fore-optics for investigation of polarization phenomena. Using both fore-optics, a variety of scenes including natural and man-made objects was imaged and these results are presented showing the utility of polarimetric imaging for anomaly detection. Analysis includes conventional Stokes-parameter based approaches as well as multivariate image analysis methods.

Project analysis and integration economic analyses summary

NASA Technical Reports Server (NTRS)

Macomber, H. L.

1986-01-01

An economic-analysis summary was presented for the manufacture of crystalline-silicon modules involving silicon ingot/sheet, growth, slicing, cell manufacture, and module assembly. Economic analyses provided: useful quantitative aspects for complex decision-making to the Flat-plate Solar Array (FSA) Project; yardsticks for design and performance to industry; and demonstration of how to evaluate and understand the worth of research and development both to JPL and other government agencies and programs. It was concluded that future research and development funds for photovoltaics must be provided by the Federal Government because the solar industry today does not reap enough profits from its present-day sales of photovoltaic equipment.

Long term attenuation statistics at 11.6 GHz in the three Italian Main Stations

NASA Astrophysics Data System (ADS)

Carassa, Francesco; Mauri, Mario; Paraboni, Aldo

1987-04-01

Results are presented from the 5-year attenuation-measurement campaign conducted with the SIRIO satellite at 11.6 and 17.8, which used near-continuous measurements at the lower frequency from the Italian ground stations at Fucino, Lario, and Spino d'Adda, and fewer measurements at the higher frequency from Fucino and Lario. The long-term statistics thus obtained have been applied in the design of the Italian domestic satellite system Italsat, which is to begin operating in 1989. Attention is presently given to annual worst month, time-of-day dependence, rain rate attenuation correlation, and frequency scaling statistics.

Identifying On-Orbit Test Targets for Space Fence Operational Testing

NASA Astrophysics Data System (ADS)

Pechkis, D.; Pacheco, N.; Botting, T.

2014-09-01

Space Fence will be an integrated system of two ground-based, S-band (2 to 4 GHz) phased-array radars located in Kwajalein and perhaps Western Australia [1]. Space Fence will cooperate with other Space Surveillance Network sensors to provide space object tracking and radar characterization data to support U.S. Strategic Command space object catalog maintenance and other space situational awareness needs. We present a rigorous statistical test design intended to test Space Fence to the letter of the program requirements as well as to characterize the system performance across the entire operational envelope. The design uses altitude, size, and inclination as independent factors in statistical tests of dependent variables (e.g., observation accuracy) linked to requirements. The analysis derives the type and number of necessary test targets. Comparing the resulting sample sizes with the number of currently known targets, we identify those areas where modelling and simulation methods are needed. Assuming hypothetical Kwajalein radar coverage and a conservative number of radar passes per object per day, we conclude that tests involving real-world space objects should take no more than 25 days to evaluate all operational requirements; almost 60 percent of the requirements can be tested in a single day and nearly 90 percent can be tested in one week or less. Reference: [1] L. Haines and P. Phu, Space Fence PDR Concept Development Phase, 2011 AMOS Conference Technical Papers.

Influence of solvent evaporation rate and formulation factors on solid dispersion physical stability.

PubMed

Wu, Jian X; Yang, Mingshi; Berg, Frans van den; Pajander, Jari; Rades, Thomas; Rantanen, Jukka

2011-12-18

New chemical entities (NCEs) often show poor water solubility necessitating solid dispersion formulation. The aim of the current study is to employ design of experiments in investigating the influence of one critical process factor (solvent evaporation rate) and two formulation factors (PVP:piroxicam ratio (PVP:PRX) and PVP molecular weight (P(MW))) on the physical stability of PRX solid dispersion prepared by the solvent evaporation method. The results showed the rank order of an increase in factors contributing to a decrease in the extent of PRX nucleation being evaporation rate>PVP:PRX>P(MW). The same rank order was found for the decrease in the extent of PRX crystal growth in PVP matrices from day 0 up to day 12. However, after 12days the rank became PVP:PRX>evaporation rate>P(MW). The effects of an increase in evaporation rate and PVP:PRX ratio in stabilizing PRX were of the same order of magnitude, while the effect from P(MW) was much smaller. The findings were confirmed by XRPD. FT-IR showed that PRX recrystallization in the PVP matrix followed Ostwald's step rule, and an increase in the three factors all led to increased hydrogen bonding interaction between PRX and PVP. The present study showed the applicability of the Quality by Design approach in solid dispersion research, and highlights the need for multifactorial analysis. Copyright © 2011 Elsevier B.V. All rights reserved.

Process weakness assessment by profiling all incoming design components

NASA Astrophysics Data System (ADS)

Zhuang, Linda; Cai, MengFeng; Zhu, Annie; Zhang, Yifan; Sweis, Jason; Lai, Ya-Chieh

2017-03-01

Foundries normally receive a large number of designs from different customers every day. It is desired to automatically profile each incoming design to quantify certain metrics like 1) the number of polygons per GDS layers 2) what kind of electrical components the design contains 3) what the dimensions of each electrical component are 4) how frequently any size of components have been used and their physical locations. This paper will present a novel method of how to generate a complete profile of components for any particular design. The component checking flow need to be completed within hours so it will have very little impact on the tape-out time. A pre-layer checking method is also run to group commonly used layers for different electrical components and then employ different layout profiling flows. The foundry does this design chip analysis in order to find potentially weak devices due to their size or special size requirements for particular electrical components. The foundry can then take pre-emptive action to avoid yield loss or make an unnecessary mask for new incoming products before fab processing starts.

Camp Greentop's Adventure Camp: We Ain't No Rudypoo's.

ERIC Educational Resources Information Center

Groff, Diane; Albright, Brian; Purvis, Katie; Creamer, Justin; Pease, Alicia

2002-01-01

A day-by-day account describes Camp Greentop's first 5-day adventure camping trip, which was attended by five individuals with disabilities and their counselors. The first day was spent in games and initiatives designed to develop communication, teamwork, and dependability. Other days were devoted to hiking, rock climbing, and whitewater rafting.…

Comparison of Inversion (“flipping”) Rates Among Different Port Designs: A Single-Center Experience

DOE Office of Scientific and Technical Information (OSTI.GOV)

Etezadi, Vahid, E-mail: vahid.etezadi@umm.edu; Trerotola, Scott O., E-mail: streroto@uphs.upenn.edu

PurposeTo compare incidence of port inversion among different types of implantable venous access devices.Materials and Methods Records of patients who underwent imaging-guided subcutaneous port placement without port fixation between July 2001 and April 2015 were reviewed with use of a quality assurance database. 1930 patients with complete follow-up (death or explant) were included in the study. Collected data included date and indication for port placement, port type, venous access site, immediate and long-term complications, indication for removal, and total number of catheter days. BMI of patients with inverted ports was also calculated.Results Port inversion within the pocket was observed inmore » 18 patients (0.9%) including 7/82 (9%) of Dignity ports, 4/126 (3%) of Vaxcel plastic arm ports, 3/142 (2%) of Smartports, 2/100 (2%) of Powerports, 1/14 (7%) of Vaccess ports, and 1/1421 (0.07%) of Vortex LP ports. Among these designs, the inversion rate was significantly lower in Vortex LP ports (0.1%) (P < 0.05). There was a trend toward higher inversion rate of Dignity ports, which have a rectangular design with a relatively narrow base. Mean dwell in inverted ports was 114 days (7–580).Conclusion The incidence of port inversion without suture fixation of the port base to the pocket is extremely low. The present study shows differences in inversion incidence based on port design.Level of Evidence: Case Series, Level IV.« less

An economic and performance design study of solar preheaters for domestic hot water heaters in North Carolina

NASA Technical Reports Server (NTRS)

Jones, C. B.; Smetana, F. O.

1977-01-01

The performance and estimated material costs for several solar preheaters for domestic hot water heaters using isolation levels present in North Carolina are presented. The effects of monthly variations in isolation and the direction of incident radiation are included. Demand is assumed at 13 gallons (49.2 liters) per day per person. The study shows that a closed circulation system with 82 gallons (310 liters) of preheated storage and 53.4 cu ft (4.94 cu m) of collector surface with single cover can be expected to cost about $800 and to repay it capital cost and interest (at 8%) in 5.2 years, assuming present electric rates increase at 5% per year.

Structured Light-Based Hazard Detection For Planetary Surface Navigation

NASA Technical Reports Server (NTRS)

Nefian, Ara; Wong, Uland Y.; Dille, Michael; Bouyssounouse, Xavier; Edwards, Laurence; To, Vinh; Deans, Matthew; Fong, Terry

2017-01-01

This paper describes a structured light-based sensor for hazard avoidance in planetary environments. The system presented here can also be used in terrestrial applications constrained by reduced onboard power and computational complexity and low illumination conditions. The sensor is on a calibrated camera and laser dot projector system. The onboard hazard avoidance system determines the position of the projected dots in the image and through a triangulation process detects potential hazards. The paper presents the design parameters for this sensor and describes the image based solution for hazard avoidance. The system presented here was tested extensively in day and night conditions in Lunar analogue environments. The current system achieves over 97 detection rate with 1.7 false alarms over 2000 images.

Effects of prenatal stress on differentiation of the sexually dimorphic nucleus of the preoptic area (SDN-POA) of the rat brain.

PubMed

Anderson, D K; Rhees, R W; Fleming, D E

1985-04-15

The present study was designed to determine the effects of prenatal malnutrition or environmental stress on the development of the sexually dimorphic nucleus of the preoptic area (SDN-POA). Pregnant rats were divided into a control group and two treatment groups (immobilization-illumination-heat or environmental stress, and nutritional stress). The two forms of stress were administered during the third trimester of gestation (days 14-20). Male and female offspring were sacrificed at birth, 20, and 60 days postnatally. The cross-sectional area of the SDN-POA was identified under light microscopy and was measured. The data confirm previous studies by showing a significant sex difference in the SDN-POA between control male and female rats. Prenatally stressed males sacrificed 20 and 60 days after birth showed SDN-POA areas 50% smaller than the nuclear areas of control males. The size of the SDN-POA of female offspring, however, was not significantly altered by prenatal treatments.

Feasibility Study of Grid Connected PV-Biomass Integrated Energy System in Egypt

NASA Astrophysics Data System (ADS)

Barakat, Shimaa; Samy, M. M.; Eteiba, Magdy B.; Wahba, Wael Ismael

2016-10-01

The aim of this paper is to present a feasibility study of a grid connected photovoltaic (PV) and biomass Integrated renewable energy (IRE) system providing electricity to rural areas in the Beni Suef governorate, Egypt. The system load of the village is analyzed through the environmental and economic aspects. The model has been designed to provide an optimal system configuration based on daily data for energy availability and demands. A case study area, Monshaet Taher village (29° 1' 17.0718"N, 30° 52' 17.04"E) is identified for economic feasibility in this paper. HOMER optimization model plan imputed from total daily load demand, 2,340 kWh/day for current energy consuming of 223 households with Annual Average Insolation Incident on a Horizontal Surface of 5.79 (kWh/m2/day) and average biomass supplying 25 tons / day. It is found that a grid connected PV-biomass IRE system is an effective way of emissions reduction and it does not increase the investment of the energy system.

Information theory in econophysics: stock market and retirement funds

NASA Astrophysics Data System (ADS)

Vogel, Eugenio; Saravia, G.; Astete, J.; Díaz, J.; Erribarren, R.; Riadi, F.

2013-03-01

Information theory can help to recognize magnetic phase transitions, what can be seen as a way to recognize different regimes. This is achieved by means of zippers specifically designed to compact data in a meaningful way at is the case for compressor wlzip. In the present contribution we first apply wlzip to the Chilean stock market interpreting the compression rates for the files storing the minute variation of the IPSA indicator. Agitated days yield poor compression rates while calm days yield high compressibility. We then correlate this behavior to the value of the five retirement funds related to the Chilean economy. It is found that the covariance between the profitability of the retirement funds and the compressibility of the IPSA values of previous day is high for those funds investing in risky stocks. Surprisingly, there seems to be no great difference among the three riskier funds contrary to what could be expected from the limitations on the portfolio composition established by the laws that regulate this market.

Detecting daily routines of older adults using sensor time series clustering.

PubMed

Hajihashemi, Zahra; Yefimova, Maria; Popescu, Mihail

2014-01-01

The aim of this paper is to develop an algorithm to identify deviations in patterns of day-to-day activities of older adults to generate alerts to the healthcare providers for timely interventions. Daily routines, such as bathroom visits, can be monitored by automated in-home sensor systems. We present a novel approach that finds periodicity in sensor time series data using clustering approach. For this study, we used data set from TigerPlace, a retirement community in Columbia, MO, where apartments are equipped with a network of motion, pressure and depth sensors. A retrospective multiple case study (N=3) design was used to quantify bathroom visits as parts of the older adult's daily routine, over a 10-day period. The distribution of duration, number, and average time between sensor hits was used to define the confidence level for routine visit extraction. Then, a hierarchical clustering was applied to extract periodic patterns. The performance of the proposed method was evaluated through experimental results.

Semi-annual report of the Department of Energy, Office of Environmental Management, Quality Assessment Program. QAP 49 summary of evaluations of 3217 reported analyses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greenlaw, P.D.

1998-12-01

This Quality Assessment Program (QAP) is designed to test the quality of the environmental measurements being reported to the Department of Energy by its contractors. Since 1976, real or synthetic environmental samples that have been prepared and thoroughly analyzed at the Environmental measurements Laboratory (EML) have been distributed at first quarterly and then semi-annually to these contractors. Their results, which are returned to EML within 90 days, are compiled with EML`s results and are reported back to the participating contractors 30 days later. A summary of the reported results is available to the participants 4 days after the reporting deadlinemore » via the Internet at www.eml.doe.gov. This report presents the results from the analysis of the 49th set of environmental quality assessment samples (QAP XLIX) that were received on or before December 1, 1998.« less

SNAP 19 Viking Program. Bimonthly technical progress report, April-May 1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1980-01-01

Monitoring and evaluation of Viking Lander 1 power system data continued. The RTG series power range as measured at the PCDA was 65 to 67 watts at finroot temperatures between 280/sup 0/F and 310/sup 0/F. The Mars Lander performance history of Viking 1 include both the minimum and maximum data for each of the SOL days. Final available power system data for Viking Lander 2 are shown. Typical SOL day cycles for mission day 1193 are presented. The RTG series power ranged from 69 to 70 watts at finroot temperatures between 270/sup 0/F and 300/sup 0/F. The Mars Lander performancemore » history for Viking 2 is shown. Power system performance data for Pioneer 10 and Pioneer Saturn (initially designated Pioneer 11) were monitored through the reporting period. After adjusting for the telemetry characteristics, the estimated RTG system net power was 114 watts for both Pioneer 10 and Pioneer Saturn.« less

People, processes, and systems: An observational study of the role of technology in rural youth mental health services.

PubMed

Orlowski, Simone; Lawn, Sharon; Matthews, Ben; Venning, Anthony; Jones, Gabrielle; Winsall, Megan; Antezana, Gaston; Bidargaddi, Niranjan; Musiat, Peter

2017-06-01

The merits of technology-based mental health service reform have been widely debated among academics, practitioners, and policy makers. The design of new technologies must first be predicated on a detailed appreciation of how the mental health system works before it can be improved or changed through the introduction of new products and services. Further work is required to better understand the nature of face-to-face mental health work and to translate this knowledge to computer scientists and system designers responsible for creating technology-based solutions. Intensive observation of day-to-day work within two rural youth mental health services in South Australia, Australia, was undertaken to understand how technology could be designed and implemented to enhance young people's engagement with services and improve their experience of help seeking. Data were analysed through a lens of complexity theory. Results highlight the variety of professional roles and services that can comprise the mental health system. The level of interconnectedness evident in the system contrasted with high levels of service self-organization and disjointed information flow. A mental health professional's work was guided by two main constructs: risk and engagement. Most clients presented with a profile of disability, disadvantage, and isolation, so complex client presentations and decision-making were core practices. Clients (and frequently, their families) engaged with services in a crisis-dependent manner, characterized by multiple disengagements and re-engagements over time. While significant opportunities exist to integrate technology into existing youth mental health services, technologies for this space must be usable for a broad range of medical, psychological and cognitive disability, social disadvantage, and accommodate repeat cycles of engagement/disengagement over time. © 2016 Australian College of Mental Health Nurses Inc.

Canada's Dominion Astrophysical Observatory and the rise of 20th Century Astrophysics and Technology

NASA Astrophysics Data System (ADS)

Hesser, James E.; Bohlender, David; Crabtree, Dennis

2015-08-01

Construction of Canada’s Dominion Astrophysical Observatory (DAO) commenced in 1914 with first light on 6 May 1918. Its varied, rich contributions to the astronomical heritage of the 20th century continue into the 21st century. The first major research observatory built with public funding on the West Coast of North America, it was Canada’s first ‘big science’ project. DAO welcomed scientists from around the world to use its 1.8m telescope designed by John Stanley Plaskett working in close collaboration with the Warner and Swasey Company of Cleveland, OH. Their original design was copied seven times around the globe, the last occasion being in the 1960s. From Day 1 the DAO welcomed the public for viewing and interaction with the small scientific staff whose early efforts would today be characterized as ‘Key Projects’. Those efforts included measuring the radial velocities of O and B stars that, interpreted through Oort’s ideas of differential rotation, determined the most reliable estimate of the size and mass of the Milky Way available until radio astronomical techniques emerged in the 1950s. The first organic molecule in interstellar space, CH, was discovered by a DAO astronomer. The first, very puzzling estimate of ~3K for the temperature of interstellar space was deduced from interstellar CN observations a year after interstellar CH and CN were discovered. DAO’s heritage of innovative instrumentation continues to the present day where expertise in optically efficient, mechanically stable spectrographs and adaptive optics are much in evidence at Mauna Kea’s CFHT, Gemini and Subaru observatories. In 2009 the DAO was designated a National Historic Site. This presentation will draw links between DAO, developments of Canadian astronomy and the emergence of Mauna Kea as an exceptional global astronomical reserve.

Broad-Bandwidth FPGA-Based Digital Polyphase Spectrometer

NASA Technical Reports Server (NTRS)

Jamot, Robert F.; Monroe, Ryan M.

2012-01-01

With present concern for ecological sustainability ever increasing, it is desirable to model the composition of Earth s upper atmosphere accurately with regards to certain helpful and harmful chemicals, such as greenhouse gases and ozone. The microwave limb sounder (MLS) is an instrument designed to map the global day-to-day concentrations of key atmospheric constituents continuously. One important component in MLS is the spectrometer, which processes the raw data provided by the receivers into frequency-domain information that cannot only be transmitted more efficiently, but also processed directly once received. The present-generation spectrometer is fully analog. The goal is to include a fully digital spectrometer in the next-generation sensor. In a digital spectrometer, incoming analog data must be converted into a digital format, processed through a Fourier transform, and finally accumulated to reduce the impact of input noise. While the final design will be placed on an application specific integrated circuit (ASIC), the building of these chips is prohibitively expensive. To that end, this design was constructed on a field-programmable gate array (FPGA). A family of state-of-the-art digital Fourier transform spectrometers has been developed, with a combination of high bandwidth and fine resolution. Analog signals consisting of radiation emitted by constituents in planetary atmospheres or galactic sources are downconverted and subsequently digitized by a pair of interleaved analog-to-digital converters (ADCs). This 6-Gsps (gigasample per second) digital representation of the analog signal is then processed through an FPGA-based streaming fast Fourier transform (FFT). Digital spectrometers have many advantages over previously used analog spectrometers, especially in terms of accuracy and resolution, both of which are particularly important for the type of scientific questions to be addressed with next-generation radiometers.

Ameliorative effect of Vernonia cinerea in vincristine-induced painful neuropathy in rats.

PubMed

Thiagarajan, Venkata Rathina Kumar; Shanmugam, Palanichamy; Krishnan, Uma Maheswari; Muthuraman, Arunachalam

2014-10-01

The present study was designed to investigate the antinociceptive potential of Vernonia cinerea (VC) on vincristine-induced painful neuropathy in rats. A chemotherapeutic agent, vincristine (50 μg/kg intraperitoneally for 10 consecutive days), was administered for the induction of neuropathic pain in rats. The painful behavioral changes were assessed using hot plate, acetone drop, paw pressure, Von Frey hair and tail immersion tests to assess the degree of hyperalgesic and allodynic pain sensation in paw and tail. Tissue biomarker changes including thiobarbituric acid reactive substances (TBARSs), reduced glutathione (GSH) and total calcium levels were estimated in sciatic nerve tissue samples to assess the degree of oxidative stress. Histopathological changes were also observed in transverse sections of rat sciatic nerve tissue. Ethanolic extract of VC leaves and pregabalin were administered for 14 consecutive days from day 0 (day of surgery). Pregabalin served as a positive control in the present study. Vincristine administration resulted in a significant reduction in painful behavioral changes along with a rise in the levels of TBARS, total calcium and decrease in GSH levels when compared with the normal control group. Furthermore, significant histopathological changes were also observed. Pretreatment with VC significantly attenuated vincristine-induced development of painful behavioral, biochemical and histological changes in a dose-dependent manner, which is similar to that of pregabalin-pretreated group. The attenuating effect of VC in vincristine-induced nociceptive painful sensation may be due to its potential of antioxidative, neuroprotective and calcium channel inhibitory action. © The Author(s) 2012.

Protective effect of thymoquinone, the main component of Nigella Sativa, against diazinon cardio-toxicity in rats.

PubMed

Danaei, Gholam Hassan; Memar, Bahram; Ataee, Ramin; Karami, Mohammad

2018-04-12

Several studies have shown that oxidative stress and cell damage can occur at very early stages of diazinon (DZN) exposure. The present study was designed to determine the beneficial effect of thymoquinone (Thy), the main component of Nigella sativa (black seed or black cumin), against DZN cardio-toxicity in rats. In the present experimental study, 48 male Wistar rats were randomly divided into six groups: control (corn oil gavages), DZN gavages (20 mg/kg/day), Thy gavages (10 mg/kg/day) and Thy + DVN gavages (2.5, 5 and 10 mg/kg/day). Treatments were continued for 28 days, then the animals were anesthetized by ether and superoxide dismutase (SOD), catalase (CAT), glutathione S-transferase (GST), lactate dehydrogenize (LDH) and glutathione peroxide (GPX) activity was evaluated. In addition, glutathione (GSH) and malondialdehyde (MDA) the heart tissue and creatinephosphokinase-MB (CPK-MB) and troponin (TPI) levels and cholinesterase activity in the blood were evaluated. DZN-induced oxidative damage and elevated the levels of the cardiac markers CK-MB, TPI, MDA and LDH and decreased SOD, CAT and cholinesterase activity and GSH level compared with the control group. Treatment with Thy reduced DZN cardio-toxicity and cholinesterase activity. The success of Thy supplementation against DZN toxicity can be attributed to the antioxidant effects of its constituents. Administration of Thy as a natural antioxidant decreased DZN cardio-toxicity and improved cholinesterase activity in rats through the mechanism of free radical scavenging.

Hepatoprotective activity of bacoside A against N-nitrosodiethylamine-induced liver toxicity in adult rats.

PubMed

Janani, Panneerselvam; Sivakumari, Kanakarajan; Parthasarathy, Chandrakesan

2009-10-01

N-Nitrosodiethylamine (DEN) is a notorious carcinogen, present in many environmental factors. DEN induces oxidative stress and cellular injury due to enhanced generation of reactive oxygen species; free radical scavengers protect the membranes from DEN-induced damage. The present study was designed to evaluate the protective effect of bacoside A (the active principle isolated from Bacopa monniera Linn.) on carcinogen-induced damage in rat liver. Adult male albino rats were pretreated with 15 mg/kg body weight/day of bacoside A orally (for 14 days) and then intoxicated with single necrogenic dose of N-nitrosodiethylamine (200 mg/kg bodyweight, intraperitonially) and maintained for 7 days. The liver weight, lipid peroxidation (LPO), and activity of serum marker enzymes (aspartate transaminases, alanine transaminases, lactate dehydrogenase, alkaline phosphatase, and gamma-glutamyl transpeptidase) were markedly increased in carcinogen-administered rats, whereas the activities of marker enzymes were near normal in bacoside A-pretreated rats. Activities of antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, glutatione-S-transferase, and reduced glutathione) in liver also decreased in carcinogen-administered rats, which were significantly elevated in bacoside A-pretreated rats. It is concluded that pretreatment of bacoside A prevents the elevation of LPO and activity of serum marker enzymes and maintains the antioxidant system and thus protects the rats from DEN-induced hepatotoxicity.

INCIDENCE AND RISK FACTORS FOR CHRONIC PELVIC PAIN AFTER HYSTEROSCOPIC STERILIZATION

PubMed Central

YUNKER, Amanda C.; RITCH, Jessica M. B.; ROBINSON, Erica F.; GOLISH, Cara T.

2014-01-01

Objective To investigate the incidence and pre-operative risk factors for developing pelvic pain after hysteroscopic sterilization using the Essure™ micro-inserts Design Retrospective cohort study (Canadian Task Force classification II-2). Setting University Medical Center Patients A total of 458 patients who underwent hysteroscopic sterilization with Essure™ between January 1, 2005 and June 30, 2012. Results The incidence of acute pelvic pain after hysteroscopic sterilization was 8.1%, and the incidence of persistent pain after 3 months post-procedure was 4.2%. The range of presentation with pain was 1 to 469 days, with a mean time of 56 days. Of the patients that developed chronic pelvic pain after the procedure, 75% presented within 130 days of the procedure. Patients with previous diagnoses of any chronic pain (chronic pelvic pain, chronic low back pain, chronic headache, and fibromyalgia) were more likely to report both acute pain (OR 6.81, 95% CI 2.95,15.73) and chronic pain (OR 6.15, 95% CI 2.10,18.10) after hysteroscopic sterilization. Conclusions Pelvic pain may develop after hysteroscopic sterilization. Patients with preexisting chronic pain diagnoses may be at increased risk of developing pelvic pain after the procedure. Fifty percent of new pelvic pain after Essure™ placement will resolve by 3 months. PMID:24952343

Adjustment and validation of a simulation tool for CSP plants based on parabolic trough technology

NASA Astrophysics Data System (ADS)

García-Barberena, Javier; Ubani, Nora

2016-05-01

The present work presents the validation process carried out for a simulation tool especially designed for the energy yield assessment of concentrating solar plants based on parabolic through (PT) technology. The validation has been carried out by comparing the model estimations with real data collected from a commercial CSP plant. In order to adjust the model parameters used for the simulation, 12 different days were selected among one-year of operational data measured at the real plant. The 12 days were simulated and the estimations compared with the measured data, focusing on the most important variables from the simulation point of view: temperatures, pressures and mass flow of the solar field, gross power, parasitic power, and net power delivered by the plant. Based on these 12 days, the key parameters for simulating the model were properly fixed and the simulation of a whole year performed. The results obtained for a complete year simulation showed very good agreement for the gross and net electric total production. The estimations for these magnitudes show a 1.47% and 2.02% BIAS respectively. The results proved that the simulation software describes with great accuracy the real operation of the power plant and correctly reproduces its transient behavior.

Cardioprotective Effects of Tualang Honey: Amelioration of Cholesterol and Cardiac Enzymes Levels.

PubMed

Khalil, Md Ibrahim; Tanvir, E M; Afroz, Rizwana; Sulaiman, Siti Amrah; Gan, Siew Hua

2015-01-01

The present study was designed to investigate the cardioprotective effects of Malaysian Tualang honey against isoproterenol- (ISO-) induced myocardial infarction (MI) in rats by investigating changes in the levels of cardiac marker enzymes, cardiac troponin I (cTnI), triglycerides (TG), total cholesterol (TC), lipid peroxidation (LPO) products, and antioxidant defense system combined with histopathological examination. Male albino Wistar rats (n = 40) were pretreated orally with Tualang honey (3 g/kg/day) for 45 days. Subcutaneous injection of ISO (85 mg/kg in saline) for two consecutive days caused a significant increase in serum cardiac marker enzymes (creatine kinase-MB (CK-MB), lactate dehydrogenase (LDH), and aspartate transaminase (AST)), cTnI, serum TC, and TG levels. In addition, ISO-induced myocardial injury was confirmed by a significant increase in heart lipid peroxidation (LPO) products (TBARS) and a significant decrease in antioxidant enzymes (SOD, GPx, GRx, and GST). Pretreatment of ischemic rats with Tualang honey conferred significant protective effects on all of the investigated biochemical parameters. The biochemical findings were further confirmed by histopathological examination in both Tualang-honey-pretreated and ISO-treated hearts. The present study demonstrates that Tualang honey confers cardioprotective effects on ISO-induced oxidative stress by contributing to endogenous antioxidant enzyme activity via inhibition of lipid peroxidation.

Microneedles 2012.

PubMed

Broderick, Kate E

2012-08-01

The second international conference on Microneedles was held on 13-15 May 2012 in Cork, Republic of Ireland, following on from a successful first meeting at the Georgia Institute of Technology (GA, USA) in May 2010. The meeting showcased the latest international developments in microneedle technology and applications. The gathering provided a platform to facilitate interdisciplinary communications and new collaborations for delegates from academic, industrial and clinical backgrounds. The meeting opened with a half-day short course on microneedle technology and applications, followed by invited lectures and poster presentations over 2 days, divided into sessions such as 'Design and technology--solid and hollow microneedles', 'Vaccine delivery' and 'Drug delivery'. This conference report summarizes the keynote and invited speaker lectures from leaders in the field such as Mark Prausnitz (Georgia Institute of Technology) and Mark Kendall (University of Queensland, Australia).

Design and Implementation of 13 Levels Multilevel Inverter for Photovoltaic System

NASA Astrophysics Data System (ADS)

Subramani, C.; Dhineshkumar, K.; Palanivel, P.

2018-04-01

This paper approaches the appearing and modernization of S-Type PV based 13- level multilevel inverter with less quantity of switch. The current S-Type Multi level inverter contains more number of switches and voltage sources. Multilevel level inverter is a be understandable among the most gainful power converters for high power application and present day applications with reduced switches. The fundamental good arrangement of the 13-level multilevel inverter is to get ventured voltage from a couple of levels of DC voltages.. The controller gives actual way day and age to switches through driver circuit using PWM methodology. The execution assessment of proposed multilevel inverter is checked using MATLAB/Simulink. This is the outstanding among other techniquem appeared differently in relation to all other existing system

Continuous 30-day measurements utilizing the monkey metabolism pod. [study of weightlessness effects

NASA Technical Reports Server (NTRS)

Pace, N.; Kodama, A. M.; Mains, R. C.; Rahlmann, D. F.; Grunbaum, B. W.

1977-01-01

A fiberglass system was previously described, using which quantitative physiological measurements could be made to study the effects of weightlessness on 10 to 14 kg adult monkeys maintained in comfortable restraint under space flight conditions. Recent improvements in the system have made it possible to obtain continuous measurements of respiratory gas exchange, cardiovascular function, and mineral balance for periods of up to 30 days on pig-tailed monkeys. It has also been possible to operate two pods which share one set of instrumentation, thereby permitting simultaneous measurements to be made on two animals by commutating signal outputs from the pods. In principle, more than two pods could be operated in this fashion. The system is compatible with Spacelab design. Representative physiological data from ground tests of the system are presented.

Flight Test Evaluation of an Unmanned Aircraft System Traffic Management (UTM) Concept for Multiple Beyond-Visual-Line-of-Sight (BVLOS) Operations

NASA Technical Reports Server (NTRS)

Johnson, Marcus; Jung, Jaewoo; Rios, Joseph; Mercer, Joey; Homola, Jeffrey; Prevot, Thomas; Mulfinger, Daniel; Kopardekar, Parimal

2017-01-01

This study evaluates a traffic management concept designed to enable simultaneous operations of multiple small unmanned aircraft systems (UAS) in the national airspace system (NAS). A five-day flight-test activity is described that examined the feasibility of operating multiple UAS beyond visual line of sight (BVLOS) of their respective operators in the same airspace. Over the five-day campaign, three groups of five flight crews operated a total of eleven different aircraft. Each group participated in four flight scenarios involving five simultaneous missions. Each vehicle was operated BVLOS up to 1.5 miles from the pilot in command. Findings and recommendations are presented to support the feasibility and safety of routine BVLOS operations for small UAS.

Flight Test Evaluation of an Unmanned Aircraft System Traffic Management (UTM) Concept for Multiple Beyond-Visual-Line-of-Sight Operations

NASA Technical Reports Server (NTRS)

Johnson, Marcus; Jung, Jaewoo; Rios, Joseph; Mercer, Joey; Homola, Jeffrey; Prevot, Thomas; Mulfinger, Daniel; Kopardekar, Parimal

2017-01-01

This study evaluates a traffic management concept designed to enable simultaneous operations of multiple small unmanned aircraft systems (UAS) in the national airspace system (NAS). A five-day flight-test activity is described that examined the feasibility of operating multiple UAS beyond visual line of sight (BVLOS) of their respective operators in the same airspace. Over the five-day campaign, three groups of five flight crews operated a total of eleven different aircraft. Each group participated in four flight scenarios involving five simultaneous missions. Each vehicle was operated BVLOS up to 1.5 miles from the pilot in command. Findings and recommendations are presented to support the feasibility and safety of routine BVLOS operations for small UAS.

Monitoring of water supply connections as an element to reduce apparent losses of water?

NASA Astrophysics Data System (ADS)

Gwoździej-Mazur, Joanna

2017-11-01

Measuring instruments are designed to measure a given physical value, to process the obtained information and forward it to the observer. They are designed to perform specific tasks in specific working conditions and meeting the envisaged requirements. The most important requirement to be met by measuring instruments, is to preserve the established metrological characteristics. The basic and most common instrument for measuring the volume of flowing water is the water meter. Selecting the right water meter in the operating conditions is not an easy issue. The problem has been further intensified by decrease of water consumption which began in the 90s of the twentieth century and continuing to the present day. As a result, there has changed the structure of water consumption in both the residential and industrial applications. In this situation, a right selection of the optimal water meter it is an important case. The article presents the results of research in the field of characteristic flows in the water supply connections in multi-family housing using modern monitoring systems. It has been presented the calculated inequality ratio of water consumption, which can be helpful when designing a plumbing systems. In addition, the structure of water consumption due to the typical flow ranges was determined.

Preliminary study of transplanting as a process for reducing levels of Vibrio vulnificus and Vibrio parahaemolyticus in shellstock oysters.

PubMed

Walton, William C; Nelson, Chris; Hochman, Mona; Schwarz, John

2013-01-01

Increasingly strict standards for harvest of oysters for the raw, half-shell market (designated as "white tag") should increase the proportion of oysters not meeting these standards (designated as "green tag"). Transplanting of green tag oysters into highsalinity waters (>20 practical salinity units) was explored as a means of returning Vibrio vulnificus and Vibrio parahaemolyticus levels to levels present on initial harvest. In summer 2011, oysters originally harvested in Louisiana were transplanted on two separate occasions (n = 2) to two sites in Mississippi Sound, AL: Sandy Bay and Dauphin Island. Oysters were tested for V. vulnificus and V. parahaemolyticus densities (by using the U.S. Food and Drug Administration enrichment method) after 2, 7, and 14 days deployed, with baseline samples taken (i) at the time of original harvest and iced, (ii) from oysters refrigerated within 1 h of harvest at <45°F ([7.2°C] white tag) and, (iii) from oysters not refrigerated during the harvest trip (green tag) but refrigerated after an 8-h trip. White and green tag oysters were sampled ∼24 h on arrival in Bon Secour, AL, put on ice, and shipped for analysis. Among baseline samples, there were no significant differences in V. vulnificus and V. parahaemolyticus densities, although the densities in the green tag oysters tended to be highest. After transplanting, V. vulnificus densities were significantly highest on day 2, with no significant differences among any of the other days within a site. On day 2, Sandy Bay had significantly greater densities of V. vulnificus than the Dauphin Island site, but no other days differed from time zero. For Vibrio parahaemolyticus, densities were greatest on day 2 and lowest at time zero, but this did not differ significantly from abundance on day 14. Average survival was 83.4% (± 3.13 SD), with no differences between sites. These preliminary results indicate that high-salinity transplanting could be an effective method of converting green tag oysters to oysters suitable for "reharvest" as white tag oysters.

Methods for Assessment of Species Richness and Occupancy Across Space, Time, Taxonomic Groups, and Ecoregions

DTIC Science & Technology

2017-03-26

logistic constraints and associated travel time between points in the central and western Great Basin. The geographic and temporal breadth of our...surveys (MacKenzie and Royle 2005). In most cases, less time is spent traveling between sites on a given day when the single-day design is implemented...with the single-day design (110 hr). These estimates did not include return- travel time , which did not limit sampling effort. As a result, we could

Conceptual Launch Vehicle and Spacecraft Design for Risk Assessment

NASA Technical Reports Server (NTRS)

Motiwala, Samira A.; Mathias, Donovan L.; Mattenberger, Christopher J.

2014-01-01

One of the most challenging aspects of developing human space launch and exploration systems is minimizing and mitigating the many potential risk factors to ensure the safest possible design while also meeting the required cost, weight, and performance criteria. In order to accomplish this, effective risk analyses and trade studies are needed to identify key risk drivers, dependencies, and sensitivities as the design evolves. The Engineering Risk Assessment (ERA) team at NASA Ames Research Center (ARC) develops advanced risk analysis approaches, models, and tools to provide such meaningful risk and reliability data throughout vehicle development. The goal of the project presented in this memorandum is to design a generic launch 7 vehicle and spacecraft architecture that can be used to develop and demonstrate these new risk analysis techniques without relying on other proprietary or sensitive vehicle designs. To accomplish this, initial spacecraft and launch vehicle (LV) designs were established using historical sizing relationships for a mission delivering four crewmembers and equipment to the International Space Station (ISS). Mass-estimating relationships (MERs) were used to size the crew capsule and launch vehicle, and a combination of optimization techniques and iterative design processes were employed to determine a possible two-stage-to-orbit (TSTO) launch trajectory into a 350-kilometer orbit. Primary subsystems were also designed for the crewed capsule architecture, based on a 24-hour on-orbit mission with a 7-day contingency. Safety analysis was also performed to identify major risks to crew survivability and assess the system's overall reliability. These procedures and analyses validate that the architecture's basic design and performance are reasonable to be used for risk trade studies. While the vehicle designs presented are not intended to represent a viable architecture, they will provide a valuable initial platform for developing and demonstrating innovative risk assessment capabilities.

An advanced concept that promises ecological and economic viability

NASA Technical Reports Server (NTRS)

Wright, B. R.; Sedgwick, T. A.; Urie, D. M.

1976-01-01

The actuality of supersonic commercial service being provided by Concorde is demonstrating to the world the advantages offered by supersonic travel for both business and recreation. Public acceptance will gradually and persistently stimulate interest to proceed with a second generation design that meets updated economic and ecological standards. It is estimated that this concept could operate profitably on world-wide routes with a revenue structure based upon economy fares. Airplanes will meet all present day ecological requirements regarding noise and emissions.

Navigation Flight Operations for Mars Pathfinder

NASA Technical Reports Server (NTRS)

Vaughan, Robin M.; Kallemeyn, Pieter H., Jr.; Spencer, David A.; Braun, Robert D.

2004-01-01

On July 4, 1997, Mars Pathfinder became the first spacecraft to land on the surface of Mars in 21 years. Pathfinder was launched on December 4, 1996 and spent seven months en route to the red planet. This report discusses the navigation flight experience for the Mars Pathfinder interplanetary cruise. In particular, orbit determination and maneuver design and execution results are presented. Special emphasis is given to the navigation role in the days and hours leading up to and including the Entry, Descent, and Landing (EDL) phase.

OpenMP Performance on the Columbia Supercomputer

NASA Technical Reports Server (NTRS)

Haoqiang, Jin; Hood, Robert

2005-01-01

This presentation discusses Columbia World Class Supercomputer which is one of the world's fastest supercomputers providing 61 TFLOPs (10/20/04). Conceived, designed, built, and deployed in just 120 days. A 20-node supercomputer built on proven 512-processor nodes. The largest SGI system in the world with over 10,000 Intel Itanium 2 processors and provides the largest node size incorporating commodity parts (512) and the largest shared-memory environment (2048) with 88% efficiency tops the scalar systems on the Top500 list.

Space Station fluid resupply

NASA Technical Reports Server (NTRS)

Winters, AL

1990-01-01

Viewgraphs on space station fluid resupply are presented. Space Station Freedom is resupplied with supercritical O2 and N2 for the ECLSS and USL on a 180 day resupply cycle. Resupply fluids are stored in the subcarriers on station between resupply cycles and transferred to the users as required. ECLSS contingency fluids (O2 and N2) are supplied and stored on station in a gaseous state. Efficiency and flexibility are major design considerations. Subcarrier approach allows multiple manifest combinations. Growth is achieved by adding modular subcarriers.

Hawking radiation in an electromagnetic waveguide?

PubMed

Schützhold, Ralf; Unruh, William G

2005-07-15

It is demonstrated that the propagation of electromagnetic waves in an appropriately designed waveguide is (for large wavelengths) analogous to that within a curved space-time--such as around a black hole. As electromagnetic radiation (e.g., microwaves) can be controlled, amplified, and detected (with present-day technology) much easier than sound, for example, we propose a setup for the experimental verification of the Hawking effect. Apart from experimentally testing this striking prediction, this would facilitate the investigation of the trans-Planckian problem.

Statistical Mechanics and Dynamics of the Outer Solar System.I. The Jupiter/Saturn Zone

NASA Technical Reports Server (NTRS)

Grazier, K. R.; Newman, W. I.; Kaula, W. M.; Hyman, J. M.

1996-01-01

We report on numerical simulations designed to understand how the solar system evolved through a winnowing of planetesimals accreeted from the early solar nebula. This sorting process is driven by the energy and angular momentum and continues to the present day. We reconsider the existence and importance of stable niches in the Jupiter/Saturn Zone using greatly improved numerical techniques based on high-order optimized multi-step integration schemes coupled to roundoff error minimizing methods.

Three days after a single exposure to ozone, the mechanism of airway hyperreactivity is dependent on substance P and nerve growth factor.

PubMed

Verhein, Kirsten C; Hazari, Mehdi S; Moulton, Bart C; Jacoby, Isabella W; Jacoby, David B; Fryer, Allison D

2011-02-01

Ozone causes persistent airway hyperreactivity in humans and animals. One day after ozone exposure, airway hyperreactivity is mediated by release of eosinophil major basic protein that inhibits neuronal M(2) muscarinic receptors, resulting in increased acetylcholine release and increased smooth muscle contraction in guinea pigs. Three days after ozone, IL-1β, not eosinophils, mediates ozone-induced airway hyperreactivity, but the mechanism at this time point is largely unknown. IL-1β increases NGF and the tachykinin substance P, both of which are involved in neural plasticity. These experiments were designed to test whether there is a role for NGF and tachykinins in sustained airway hyperreactivity following a single ozone exposure. Guinea pigs were exposed to filtered air or ozone (2 parts per million, 4 h). In anesthetized and vagotomized animals, ozone potentiated vagally mediated airway hyperreactivity 24 h later, an effect that was sustained over 3 days. Pretreatment with antibody to NGF completely prevented ozone-induced airway hyperreactivity 3 days, but not 1 day, after ozone and significantly reduced the number of substance P-positive airway nerve bundles. Three days after ozone, NK(1) and NK(2) receptor antagonists also blocked this sustained hyperreactivity. Although the effect of inhibiting NK(2) receptors was independent of ozone, the NK(1) receptor antagonist selectively blocked vagal hyperreactivity 3 days after ozone. These data confirm mechanisms of ozone-induced airway hyperreactivity change over time and demonstrate 3 days after ozone that there is an NGF-mediated role for substance P, or another NK(1) receptor agonist, that enhances acetylcholine release and was not present 1 day after ozone.

Three days after a single exposure to ozone, the mechanism of airway hyperreactivity is dependent on substance P and nerve growth factor

PubMed Central

Verhein, Kirsten C.; Hazari, Mehdi S.; Moulton, Bart C.; Jacoby, Isabella W.; Jacoby, David B.

2011-01-01

Ozone causes persistent airway hyperreactivity in humans and animals. One day after ozone exposure, airway hyperreactivity is mediated by release of eosinophil major basic protein that inhibits neuronal M2 muscarinic receptors, resulting in increased acetylcholine release and increased smooth muscle contraction in guinea pigs. Three days after ozone, IL-1β, not eosinophils, mediates ozone-induced airway hyperreactivity, but the mechanism at this time point is largely unknown. IL-1β increases NGF and the tachykinin substance P, both of which are involved in neural plasticity. These experiments were designed to test whether there is a role for NGF and tachykinins in sustained airway hyperreactivity following a single ozone exposure. Guinea pigs were exposed to filtered air or ozone (2 parts per million, 4 h). In anesthetized and vagotomized animals, ozone potentiated vagally mediated airway hyperreactivity 24 h later, an effect that was sustained over 3 days. Pretreatment with antibody to NGF completely prevented ozone-induced airway hyperreactivity 3 days, but not 1 day, after ozone and significantly reduced the number of substance P-positive airway nerve bundles. Three days after ozone, NK1 and NK2 receptor antagonists also blocked this sustained hyperreactivity. Although the effect of inhibiting NK2 receptors was independent of ozone, the NK1 receptor antagonist selectively blocked vagal hyperreactivity 3 days after ozone. These data confirm mechanisms of ozone-induced airway hyperreactivity change over time and demonstrate 3 days after ozone that there is an NGF-mediated role for substance P, or another NK1 receptor agonist, that enhances acetylcholine release and was not present 1 day after ozone. PMID:21056958

Cost Effectiveness Analysis between Boarding and Day Secondary Students in Kenya

ERIC Educational Resources Information Center

Jagero, N.; Ayodo, T. M.; Agak, J. A.

2011-01-01

This paper examines the cost effectiveness of educating boarding and day secondary students in Kisumu district in Kenya. The research designs used in this study were descriptive survey and casual comparative designs. The population consisted of five head teachers, 140 form four teachers and 609 form four students. Saturated and systematic random…

Planning, Supervision and Quality of Instructional Leadership of Girls' Day Secondary Schools in Kaduna State, Nigeria

ERIC Educational Resources Information Center

Duruh, Benjamin C.

2018-01-01

This study investigated the Planning, Supervision and Quality of Instructional Leadership of Girls' Day Secondary Schools in Kaduna State. The research design adopted was a survey design. The independent variables were the respondents which include principals, teachers, students, parents and government officials while dependent variable includes…

Educational Website Design Process: Changes in TPACK Competencies and Experiences

ERIC Educational Resources Information Center

Önal, Nezih; Alemdag, Ecenaz

2018-01-01

The number of technological pedagogical and content knowledge (TPACK) studies has been increasing day by day; however, limited number of studies has provided both quantitative and qualitative findings based on teachers' learning by design experiences. This study aimed to reveal the changes in pre-service teachers' TPACK competencies in the…

77 FR 9251 - Designation of a Class of Employees for Addition to the Special Exposure Cohort

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-16

... DEPARTMENT OF HEALTH AND HUMAN SERVICES Designation of a Class of Employees for Addition to the Special Exposure Cohort AGENCY: National Institute for Occupational Safety and Health (NIOSH), Centers for..., for a number of work days aggregating at least 250 work days, occurring either solely under this...

What's Happening in May? A Salute to Women Educators in Connecticut.

ERIC Educational Resources Information Center

Toro, Leonor; And Others

Brief information is given on May events celebrated by Puerto Ricans: May Day; Mother's Day; World Red Cross Day; Armed Forces Day; Memorial Day; and the birthdays of Horace Mann ("Father of the Common Schools"), Harry S. Truman, Luis Llorens Torres (poet), Ralph Waldo Emerson (poet), and Patrick Henry (stateman and orator). Designed as…

Toxicity profiles in rats treated with tumorigenic and nontumorigenic triazole conazole fungicides: Propiconazole, triadimefon, and myclobutanil.

PubMed

Wolf, Douglas C; Allen, James W; George, Michael H; Hester, Susan D; Sun, Guobin; Moore, Tanya; Thai, Sheau-Fung; Delker, Don; Winkfield, Ernest; Leavitt, Sharon; Nelson, Gail; Roop, Barbara C; Jones, Carlton; Thibodeaux, Julie; Nesnow, Stephen

2006-01-01

Conazoles are a class of azole based fungicides used in agriculture and as pharmaceutical products. They have a common mode of antifungal action through inhibition of ergosterol biosynthesis. Some members of this class have been shown to be hepatotoxic and will induce mouse hepatocellular tumors and/or rat thyroid follicular cell tumors. The particular mode of toxic and tumorigenic action for these compounds is not known, however it has been proposed that triadimefon-induced rat thyroid tumors arise through the specific mechanism of increased TSH. The present study was designed to identify commonalities of effects across the different conazoles and to determine unique features of the tissue responses that suggest a toxicity pathway and a mode of action for the observed thyroid response for triadimefon. Male Wistar/Han rats were treated with triadimefon (100, 500, 1800 ppm), propiconazole (100, 500, 2500 ppm), or myclobutanil (100, 500, 2000 ppm) in feed for 4, 30, or 90 days. The rats were evaluated for clinical signs, body and liver weight, histopathology of thyroid and liver, hepatic metabolizing enzyme activity, and serum T3, T4, TSH, and cholesterol levels. There was a dose-dependent increase in liver weight but not body weight for all treatments. The indication of cytochrome induction, pentoxyresorufin O-dealkylation (PROD) activity, had a dose-related increase at all time points for all conazoles. Uridine diphopho-glucuronosyl transferase (UDPGT), the T4 metabolizing enzyme measured as glucuronidation of 1-naphthol, was induced to the same extent after 30 and 90 days for all three conazoles. Livers from all high dose treated rats had centrilobular hepatocyte hypertrophy after 4 days, while only triadimefon and propiconazole treated rats had hepatocyte hypertrophy after 30 days, and only triadimefon treated rats had hepatocyte hypertrophy after 90 days. Thyroid follicular cell hypertrophy, increased follicular cell proliferation, and colloid depletion were present only after 30 days in rats treated with the high dose of triadimefon. A dose-dependent decrease in T4 was present after 4 days with all 3 compounds but only the high doses of propiconazole and triadimefon produced decreased T4 after 30 days. T3 was decreased after high-dose triadimefon after 4 days and in a dose-dependent manner for all compounds after 30 days. Thyroid hormone levels did not differ from control values after 90 days and TSH was not increased in any exposure group. A unique pattern of toxic responses was not identified for each conazole and the hypothesized mode of action for triadimefon-induced thyroid gland tumors was not supported by the data.

Is Full-Day Kindergarten Worth It? an Academic Comparison of Full-Day and Half-Day Kindergarten Programs

ERIC Educational Resources Information Center

Romines, Robert A.

2012-01-01

The purpose of this study is to answer this question: Which is academically superior for young children, full-or half-day kindergarten? This inquiry-oriented case study was designed to compare and contrast students who attended half-day versus full-day kindergarten programs in a suburban public school district. The study is necessary because the…

Repeated Use of Immersive Virtual Reality Therapy to Control Pain during Wound Dressing Changes in Pediatric and Adult Burn Patients

PubMed Central

Faber, Albertus W.; Patterson, David R.; Bremer, Marco

2012-01-01

Objective The current study explored whether immersive virtual reality continues to reduce pain (via distraction) during more than one wound care session per patient. Patients: Thirty six patients aged 8 to 57 years (mean age of 27.7 years), with an average of 8.4% total body surface area burned (range .25 to 25.5 TBSA) received bandage changes, and wound cleaning. Methods Each patient received one baseline wound cleaning/debridement session with no-VR (control condition) followed by one or more (up to seven) subsequent wound care sessions during VR. After each wound care session (one session per day), worst pain intensity was measured using a Visual Analogue Thermometer (VAT), the dependent variable. Using a within subjects design, worst pain intensity VAT during wound care with no-VR (baseline, Day 0) was compared to pain during wound care while using immersive virtual reality (up to seven days of wound care during VR). Results Compared to pain during no-VR Baseline (Day 0), pain ratings during wound debridement were statistically lower when patients were in virtual reality on Days 1, 2 and 3, and although not significant beyond day 3, the pattern of results from Days 4, 5, and 6 are consistent with the notion that VR continues to reduce pain when used repeatedly. Conclusions Results from the present study suggest that VR continues to be effective when used for three (or possibly more) treatments during severe burn wound debridement. PMID:23970314

A Tunable, Biodegradable, Thin-Film Polymer Device as a Long-Acting Implant Delivering Tenofovir Alafenamide Fumarate for HIV Pre-exposure Prophylaxis

PubMed Central

Schlesinger, Erica; Johengen, Daniel; Luecke, Ellen; Rothrock, Ginger; McGowan, Ian; van der Straten, Ariane; Desai, Tejal

2016-01-01

Purpose The effectiveness of Tenofovir based HIV pre-exposure prophylaxis (PrEP) is proven, but hinges on correct and consistent use. User compliance and therapeutic effectiveness can be improved by long acting drug delivery systems. Here we describe a thin-film polymer device (TFPD) as a biodegradable subcutaneous implant for PrEP. Methods A thin-film polycaprolactone (PCL) membrane controls drug release from a reservoir. To achieve membrane controlled release, TAF requires a formulation excipient such as PEG300 to increase the dissolution rate and reservoir solubility. Short-term In vitro release studies are used to develop an empirical design model, which is applied to the production of in vitro prototype devices demonstrating up to 90-days of linear release and TAF chemical stability. Results The size and shape of the TFPD are tunable, achieving release rates ranging from 0.5–4.4 mg/day in devices no larger than a contraceptive implant. Based on published data for oral TAF, subcutaneous constant-rate release for HIV PrEP is estimated at < 2.8mg/day. Prototype devices demonstrated linear release at 1.2mg/day for up to 90 days and at 2.2mg/day for up to 60 days. Conclusions We present a biodegradable TFPD for subcutaneous delivery of TAF for HIV PrEP. The size, shape and release rate of the device are tunable over a > 8-fold range. PMID:26975357

'Away Days' in multi-centre randomised controlled trials: a questionnaire survey of their use and a case study on the effect of one Away Day on patient recruitment.

PubMed

Jefferson, Laura; Cook, Liz; Keding, Ada; Brealey, Stephen; Handoll, Helen; Rangan, Amar

2015-11-06

'Away Days' (trial promotion and training events for trial site personnel) are a well-established method used by trialists to encourage engagement of research sites in the recruitment of patients to multi-centre randomised controlled trials (RCTs). We explored the use of Away Days in multi-centre RCTs and analysed the effect on patient recruitment in a case study. Members of the United Kingdom Trial Managers' Network were surveyed in June 2013 to investigate their experiences in the design and conduct of Away Days in RCTs. We used data from a multi-centre pragmatic surgical trial to explore the effects of an Away Day on the screening and recruitment of patients. A total of 94 people responded to the survey. The majority (78%), who confirmed had organised an Away Day previously, found them to be useful. This is despite their costs.. There was no evidence, however, from the analysis of data from a surgical trial that attendance at an Away Day increased the number of patients screened or recruited at participating sites. Although those responsible for managing RCTs in the UK tend to believe that trial Away Days are beneficial, evidence from a multi-centre surgical trial shows no improvement on a key indicator of trial success. This points to the need to carefully consider the aims, design and conduct of Away Days. Further more rigorous research nested within RCTs would be valuable to evaluate the design and conduct of Away Days. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Ionospheric observations using GPS radio occultation from a nanosat platform

NASA Astrophysics Data System (ADS)

Bishop, R. L.; Redding, M.; Straus, P. R.

2012-12-01

The Compact Total Electron Content Sensor (CTECS) is a GPS radio occultation instrument designed for cubesat platforms that utilizes a COTS receiver, modified firmware, and a custom designed antenna. CTECS was placed on the Pico Satellite Solar Cell Testbed 2 (PSSC2) nanosat that was installed on the Space Shuttle Atlantis (STS-135). PSSC2 was successfully released from the shuttle on 20 July 2011 near 380 km altitude. Because of attitude control and power issues, only 13.5 hours of data was collected during its approximately 5-month mission life. Total Electron Content (TEC) observations were obtained and this presentation will present a summary of all TEC data analyzed from the mission. We will discuss the instrument challenges encountered, data issues, and future planned improvements to CTECS. Two CTECS flight units were delivered in the spring of 2012 for integration on the SMC/XR Space Environment NanoSatellite Experiment (SENSE) spacecrafts that are scheduled for launch in the second half of 2013. We will present a summary of the SENSE mission, performance of the improved CTECS sensors, and the results of ground and day-in-the-life testing.

Proposed primary endpoints for use in clinical trials that compare treatment options for bloodstream infection in adults: a consensus definition.

PubMed

Harris, P N A; McNamara, J F; Lye, D C; Davis, J S; Bernard, L; Cheng, A C; Doi, Y; Fowler, V G; Kaye, K S; Leibovici, L; Lipman, J; Llewelyn, M J; Munoz-Price, S; Paul, M; Peleg, A Y; Rodríguez-Baño, J; Rogers, B A; Seifert, H; Thamlikitkul, V; Thwaites, G; Tong, S Y C; Turnidge, J; Utili, R; Webb, S A R; Paterson, D L

2017-08-01

To define standardized endpoints to aid the design of trials that compare antibiotic therapies for bloodstream infections (BSI). Prospective studies, randomized trials or registered protocols comparing antibiotic therapies for BSI, published from 2005 to 2016, were reviewed. Consensus endpoints for BSI studies were defined using a modified Delphi process. Different primary and secondary endpoints were defined for pilot (small-scale studies designed to evaluate protocol design, feasibility and implementation) and definitive trials (larger-scale studies designed to test hypotheses and influence clinical practice), as well as for Staphylococcus aureus and Gram-negative BSI. For pilot studies of S. aureus BSI, a primary outcome of success at day 7 was defined by: survival, resolution of fever, stable/improved Sequential Organ Failure Assessment (SOFA) score and clearance of blood cultures, with no microbiologically confirmed failure up to 90 days. For definitive S. aureus BSI studies, a primary outcome of success at 90 days was defined by survival and no microbiologically confirmed failure. For pilot studies of Gram-negative BSI, a primary outcome of success at day 7 was defined by: survival, resolution of fever and symptoms related to BSI source, stable or improved SOFA score and negative blood cultures. For definitive Gram-negative BSI studies, a primary outcome of survival at 90 days supported by a secondary outcome of success at day 7 (as previously defined) was agreed. These endpoints provide a framework to aid future trial design. Further work will be required to validate these endpoints with respect to patient-centred clinical outcomes. Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases. All rights reserved.

Next-day residual effects of hypnotics in DSM-IV primary insomnia: a driving simulator study with simultaneous electroencephalogram monitoring.

PubMed

Staner, Luc; Ertlé, Stéphane; Boeijinga, Peter; Rinaudo, Gilbert; Arnal, Marie Agnès; Muzet, Alain; Luthringer, Rémy

2005-10-01

Most studies that investigated the next-day residual effects of hypnotic drugs on daytime driving performances were performed on healthy subjects and after a single drug administration. In the present study, we further examine whether the results of these studies could be generalised to insomniac patients and after repeated drug administration. Single and repeated (7 day) doses of zolpidem (10 mg), zopiclone (7.5 mg), lormetazepam (1 mg) or placebo were administered at bedtime in a crossover design to 23 patients (9 men and 14 women aged 38.8+/-2.0 years) with Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) primary insomnia. Driving tests were performed 9-11 h post-dose. Results showed that treatment effects were evidenced for subjective sleep, for driving abilities, and for electroencephalogram (EEG) recorded before (resting EEG) and during the driving simulation test (driving EEG). Compared to placebo, zopiclone increased the number of collisions and lormetazepam increased deviation from speed limit and deviation from absolute speed, whereas zolpidem did not differentiate from placebo on these analyses. EEG recordings showed that in contrast to zolpidem, lormetazepam and zopiclone induced typical benzodiazepine-like alterations, suggesting that next-day poor driving performance could relate to a prolonged central nervous system effect of these two hypnotics. The present results corroborate studies on healthy volunteers showing that residual effects of hypnotics increase with their half-lives. The results further suggest that drugs preserving physiological EEG rhythms before and during the driving simulation test 9-11 h post-dose, such as zolpidem, do not influence next-day driving abilities.

Reversal of alcohol induced testicular hyperlipidemia by supplementation of ascorbic acid and its comparison with abstention in male guinea pigs.

PubMed

Radhakrishnakartha, Harikrishnan; Appu, Abhilash Puthuvelvippel; Madambath, Indira

2014-02-01

Chronic ethanol exposure causes hyperlipidemia. The present study was designed to investigate the impact of ascorbic acid supplementation on ethanol induced hyperlipidemia in testis and to compare it with that of abstinence from taking alcohol. Thirty-six male guinea pigs were divided into two groups and were maintained for 90 days as follows (1) control (C) (2) ethanol treated group (E) (4 g/kg body wt/day). Ethanol was administered for 90 days and on 90th day, alanine amino transaminase (ALT), aspartate amino transaminase (AST) and γ-glutamyltransferase (GGT) in serum was assayed. The animals in the ethanol group were further divided into an ascorbic acid supplemented group (25 mg/100 g body wt/day) (E+AA) and an ethanol abstention group (EAG) and those in the control group were divided into a control group and a control+ascorbic acid group (C+AA). There was significant increase in levels of testicular cholesterol, free fatty acid, phospholipids and triglycerides in the ethanol group. There was also a significant increase in the activity of HMG CoA reductase and decrease in activity of testicular glucose-6-phosphate dehydrogenase (G6PDH) and malic enzyme in ethanol-ingested animals that further led to decreased levels of serum testosterone. Alcohol administration also enhanced the activity of testicular alcohol dehydrogenase (ADH). Ascorbic acid supplementation and abstention altered all these parameters induced by chronic alcohol administration. Histological studies were also in line with the above results. Ascorbic acid was able to reinstate the cholesterol homeostasis in testis which could have further restored the testicular steroidogenesis. The present study demonstrated that ascorbic acid is effective in reducing the hyperlipidemia induced by chronic alcohol administration and produced a better recovery than abstention.

Grounding and lightning protection. Volume 5

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robinson, M.D.

1987-12-31

Grounding systems protect personnel and equipment by isolating faulted systems and dissipating transient currents. Lightning protection systems minimize the possible consequences of a direct strike by lightning. This volume focuses on design requirements of the grounding system and on present-day concepts used in the design of lightning protection systems. Various types of grounding designs are presented, and their advantages and disadvantages discussed. Safety, of course, is the primary concern of any grounding system. Methods are shown for grounding the non-current-carrying parts of electrical equipment to reduce shock hazards to personnel. Lightning protection systems are installed on tall structures (such asmore » chimneys and cooling towers) to minimize the possibility of structural damage caused by direct lightning strokes. These strokes may carry currents of 200,000 A or more. The volume examines the formation and characteristics of lightning strokes and the way stroke characteristics influence the design of lightning protection systems. Because a large portion of the grounding system is buried in soil or concrete, it is not readily accessible for inspection or repair after its installation. The volume details the careful selection and sizing of materials needed to ensure a long, maintenance-free life for the system. Industry standards and procedures for testing the adequacy of the grounding system are also discussed.« less

Horizontal lifelines - review of regulations and simple design method considering anchorage rigidity.

PubMed

Galy, Bertrand; Lan, André

2018-03-01

Among the many occupational risks construction workers encounter every day falling from a height is the most dangerous. The objective of this article is to propose a simple analytical design method for horizontal lifelines (HLLs) that considers anchorage flexibility. The article presents a short review of the standards and regulations/acts/codes concerning HLLs in Canada the USA and Europe. A static analytical approach is proposed considering anchorage flexibility. The analytical results are compared with a series of 42 dynamic fall tests and a SAP2000 numerical model. The experimental results show that the analytical method is a little conservative and overestimates the line tension in most cases with a maximum of 17%. The static SAP2000 results show a maximum 2.1% difference with the analytical method. The analytical method is accurate enough to safely design HLLs and quick design abaci are provided to allow the engineer to make quick on-site verification if needed.