Sample records for present day state

  1. Examination of cortisol and state anxiety at an academic setting with and without oral presentation.

    PubMed

    Merz, Christian Josef; Wolf, Oliver Tobias

    2015-01-01

    Holding oral presentations in a university course is perceived as stressful and can increase stress hormone concentrations and state anxiety. In such a naturalistic setting, further attention should be paid to the relationship between psychological and hormonal measures of acute stress, as well as women's intake of hormonal contraceptives as a potential moderating variable. In the present study, 76 healthy students gave saliva samples before and after their oral presentations in a university course as well as on a second, control day in the same course without giving an oral presentation. Anticipatory state anxiety was rated on both days. Cortisol concentrations as well as state anxiety were substantially higher on the presentation relative to the control day. During the oral presentation, an increase in cortisol concentrations was observed, whereas a decrease occurred on the control day. Nearly the same picture emerged for both variables when looking at men, women taking hormonal contraceptives and free-cycling women separately. A positive correlation was found between the change in anticipatory state anxiety in the presentation compared to the control day and cortisol concentrations before and after the oral presentation. Concluding, oral presentations constitute a potent stressor and do not seem to be substantially different between men, free-cycling women and women taking hormonal contraceptives. Future studies may want to explore changes associated with specific menstrual cycle phases and with specific hormonal contraceptives.

  2. On the long-term memory of the Greenland Ice Sheet

    NASA Astrophysics Data System (ADS)

    Rogozhina, I.; Martinec, Z.; Hagedoorn, J. M.; Thomas, M.; Fleming, K.

    2011-03-01

    In this study, the memory of the Greenland Ice Sheet (GIS) with respect to its past states is analyzed. According to ice core reconstructions, the present-day GIS reflects former climatic conditions dating back to at least 250 thousand years before the present (kyr BP). This fact must be considered when initializing an ice sheet model. The common initialization techniques are paleoclimatic simulations driven by atmospheric forcing inferred from ice core records and steady state simulations driven by the present-day or past climatic conditions. When paleoclimatic simulations are used, the information about the past climatic conditions is partly reflected in the resulting present-day state of the GIS. However, there are several important questions that need to be clarified. First, for how long does the model remember its initial state? Second, it is generally acknowledged that, prior to 100 kyr BP, the longest Greenland ice core record (GRIP) is distorted by ice-flow irregularities. The question arises as to what extent do the uncertainties inherent in the GRIP-based forcing influence the resulting GIS? Finally, how is the modeled thermodynamic state affected by the choice of initialization technique (paleo or steady state)? To answer these questions, a series of paleoclimatic and steady state simulations is carried out. We conclude that (1) the choice of an ice-covered initial configuration shortens the initialization simulation time to 100 kyr, (2) the uncertainties in the GRIP-based forcing affect present-day modeled ice-surface topographies and temperatures only slightly, and (3) the GIS forced by present-day climatic conditions is overall warmer than that resulting from a paleoclimatic simulation.

  3. Family Day Care Licensing Study: Family Day Care Advocacy Project, 1986.

    ERIC Educational Resources Information Center

    Ainslie, Julie; And Others

    Fifth of a series, this report presents the results of a nationwide 1986 survey of state regulatory systems for family day care services. Findings indicate that in most states the number of regulated providers has increased dramatically since the 1984 study, while federal and state funding has decreased, making regulatory efforts more difficult.…

  4. [Trace and anxiety of nursing mothers with insufficient and normal breast feeding indicators].

    PubMed

    Aragaki, Ilva Marico Mizumoto; Silva, Isília Aparecida; dos Santos, Jair Lício Ferreira

    2006-09-01

    The objective of this study was to identify and compare the trace and the anxiety state on the 10th day postpartum and the anxiety state on the 30th day postpartum of primiparous and multiparous nursing mothers who present insufficient breast feeding indicators and nursing mothers with normal breast feeding, in order to verify the possible relationships between the anxiety state of the nursing mothers in those two moments with the insufficient breast feeding indicators presented. This is an exploratory and descriptive study, whose data has been gotten from 168 nursing mothers and their children by means of interviews in nursing consultations in the 10th and 30th day postpartum. The results obtained showed that primiparous and multiparous with insufficient breast feeding and primiparous with normal lactation presented higher anxiety state trace than the anxiety state on the 10th and 30th day postpartum. There was remission of the maternal signals of anxiety with the passing of time, which may be caused by the correction of the breast feeding technique and support to the nursing mothers.

  5. The effect of short-term alcohol restriction on risk of alcohol-related injury: A state wide population-based study.

    PubMed

    Liang, Wenbin; Gilmore, William; Chikritzhs, Tanya

    2016-02-01

    Alcohol consumption and related harms are largely determined by both demand and supply of alcohol. Across Western Australia, under state licensing laws, there are state-wide alcohol sales restrictions imposed on Good Friday and Christmas Day each year. This study aimed to evaluate the effect of the Good Friday and Christmas Day state-wide alcohol restrictions on the risk of alcohol-related injuries presenting at emergency departments. This is a population-based cohort study using ED injury presentation data for the period 1st January 2002 to 1st January 2015. Risk of injury during the alcohol-related time of day affected by the alcohol restrictions (intervention periods, including Good Friday and Christmas Day) were compared to the same time of day over a number of control days. Multivariable Poisson regression model was used to perform the analysis. The crude injury risk was considerably lower during the alcohol restriction periods compared to control periods in both metropolitan and non-metropolitan areas. The protective effect observed on the days of the alcohol restrictions remained significant, and largely unchanged, when potential confounding effects were controlled for. The significant reduction in alcohol-related injury presentations observed for public holiday periods with alcohol restrictions were likely caused by the alcohol restriction policy and its direct effect on alcohol supply. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. The Day Care Challenge: The Unmet Needs of Mothers and Children.

    ERIC Educational Resources Information Center

    Keyserling, Mary Dublin

    An overview of the present shortage of day care facilities in the United States is presented in this speech. Statistics cited on the number of working mothers with children under the age of 6 and the number of day care licensed homes and centers show that the shortage of licensed day care facilities is much more acute than it was five years ago.…

  7. Stressors and affective states among professional rugby union players.

    PubMed

    Nicholls, A R; Backhouse, S H; Polman, R C J; McKenna, J

    2009-02-01

    The purpose of the present study was to examine (a) the sources of sport and non-sport stress and their associated symptoms on rest days, training days, and match days and (b) the temporal aspects of sources and symptoms of stress and affective states. Professional male rugby union players (n=16) completed the Daily Analysis of Life Demands in Athletes (DALDA) and the Activation Deactivation Adjective Check List (AD ACL) for 28 days. On match days players reported that few stressors were "worse than normal." Most stressors were "worse than normal" on training days followed by rest days and more stressors were "worse than normal" on the day after a match than on match days. Further, players reported an unpleasant, low activation state across the three analysis days, suggesting they were in an overtrained state. The findings of this study demonstrate that professional rugby players experience negative affect and a multitude of sport and non-sport stressors. Early detection of stressors and negative affective states could help prevent symptoms of overtraining and burnout and facilitate optimal training and sporting performance. Coaches and practitioners are encouraged to integrate the DALDA and AD ACL in their training and performance monitoring regimes.

  8. Day-Care Regulation: Serving Children or Bureaucrats? Cato Institute Policy Analysis No. 59.

    ERIC Educational Resources Information Center

    Lehrman, Karen; Pace, Jana

    If the supply of day care is ever to keep pace with the rapidly rising demand, it is essential that there be a favorable climate for its growth. At present there is not, and the regulatory obstacle course laid out by state and local officials is in large part why. State barriers to the provision of day care involve licensing and registration and…

  9. A shortened protocol for assessing cognitive bias in rats.

    PubMed

    Brydges, Nichola M; Hall, Lynsey

    2017-07-15

    Reliable measurement of affective state in animals is a significant goal of animal welfare. Such measurements would also improve the validity of pre-clinical mental health research which relies on animal models. However, at present, affective states in animals are inaccessible to direct measurement. In humans, changes in cognitive processing can give reliable indications of emotional state. Therefore, similar techniques are increasingly being used to gain proxy measures of affective states in animals. In particular, the 'cognitive bias' assay has gained popularity in recent years. Major disadvantages of this technique include length of time taken for animals to acquire the task (typically several weeks), negative experiences associated with task training, and issues of motivation. Here we present a shortened cognitive bias protocol using only positive reinforcers which must actively be responded to. The protocol took an average of 4days to complete, and produced similar results to previous, longer methods (minimum 30days). Specifically, rats housed in standard laboratory conditions demonstrated negative cognitive biases when presented with ambiguous stimuli, and took longer to make a decision when faced with an ambiguous stimulus. Compared to previous methods, this protocol is significantly shorter (average 4days vs. minimum 30days), utilises only positive reinforcers to avoid inducing negative affective states, and requires active responses to all cues, avoiding potential confounds of motivational state. We have successfully developed a shortened cognitive bias protocol, suitable for use with laboratory rats. Copyright © 2017 The Author(s). Published by Elsevier B.V. All rights reserved.

  10. 78 FR 62311 - Leif Erikson Day, 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-16

    ... Erikson Day, 2013 By the President of the United States of America A Proclamation More than a millennium... off course in the North Atlantic, and they landed in present-day Canada, making them the first... idea into something great. On Leif Erikson Day, we celebrate that legacy and the countless Norwegian...

  11. 75 FR 56465 - National Grandparents Day, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... National Grandparents Day, 2010 By the President of the United States of America A Proclamation Throughout... traditions of our heritage are passed down through generations. On National Grandparents Day, we honor those... Day presents a chance to show our profound appreciation and respect for the central roles that family...

  12. Finding a Life Worth Living: Meaning in Life and Graduation from College.

    PubMed

    Wilt, Joshua; Bleidorn, Wiebke; Revelle, William

    2016-01-01

    Graduation from college is an important milestone for young adults, marked by mixed emotions and poignancy, and therefore is an especially salient context for studying meaning in life. The present research used experience-sampling methodology to examine the antecedents and consequences of students' experience of meaning in life over the course of graduation. Participants were 74 graduating students who provided a total of 538 reports over the span of three days, including commencement day. Increased levels of state meaning in life during the days around commencement were linked to spending time with people in general and with family in particular, as well as thinking about one's years in college. Thinking about one's years in college mediated the effects of present company on state meaning in life. Graduates who experienced higher levels of state meaning in life during the days around their commencement ceremony had higher trait levels of meaning in life one week following commencement. We discuss how making meaning of a poignant experience has implications for healthy psychological development.

  13. Family Day Care in the United States: Family Day Care Systems. Final Report of the National Day Care Home Study. Volume 5.

    ERIC Educational Resources Information Center

    Grasso, Janet; Fosburg, Steven

    Fifth in a series of seven volumes reporting the design, methodology, and findings of the 4-year National Day Care Home Study (NDCHS), this volume presents a descriptive and statistical analysis of the day care institutions that administer day care systems. These systems, such as Learning Unlimited in Los Angeles and the family day care program of…

  14. Major Aspects of Day Care: Statements and Articles.

    ERIC Educational Resources Information Center

    Hutchinson, Shauneen, Comp.

    Published material concerned with various types of day care are provided. The material has been separated into four different sections: (1) General, which describes underlying policy, trends, and the present status of day care in the United States; (2) Working Mothers, covering day care arrangements made by women in the labor force; (3) Foreign,…

  15. How-to-Do-It: Biotechnology in Three Days.

    ERIC Educational Resources Information Center

    Gardner, Alan M.

    1988-01-01

    Outlines a three-day unit for presenting biotechnology. States that the approach surveys the processes of enzyme restriction, ligation, transformations of recombinant plasmids, and gel electrophoresis. Diagrams accompany the article. (RT)

  16. Earth Day Plus 20, and Counting.

    ERIC Educational Resources Information Center

    Gilbert, Bil

    1990-01-01

    Presents a historical perspective of the environmental movement in the United States, beginning with Earth Day, 1970. Profiles "environmentalists" and describes environmental activities, achievements with environmental reform, turning points, and proenvironmental legislation from 1970-90. (MCO)

  17. National Research Conference on Day Programs for Hearing Impaired Children (Lake Mohonk, New York, May 10-13, 1967). Final Report.

    ERIC Educational Resources Information Center

    Mulholland, Ann M.; Fellendorf, George W.

    State needs in public school education for the hearing impaired and steps in the development of comprehensive state planning are presented along with recommendations of conference participants, a summary report, and models for regional planning, day programs, and the team approach. The interest of the Alexander Graham Bell Association and the U.S.…

  18. Finding a Life Worth Living: Meaning in Life and Graduation from College

    PubMed Central

    Wilt, Joshua; Bleidorn, Wiebke; Revelle, William

    2016-01-01

    Graduation from college is an important milestone for young adults, marked by mixed emotions and poignancy, and therefore is an especially salient context for studying meaning in life. The present research used experience-sampling methodology to examine the antecedents and consequences of students’ experience of meaning in life over the course of graduation. Participants were 74 graduating students who provided a total of 538 reports over the span of three days, including commencement day. Increased levels of state meaning in life during the days around commencement were linked to spending time with people in general and with family in particular, as well as thinking about one's years in college. Thinking about one's years in college mediated the effects of present company on state meaning in life. Graduates who experienced higher levels of state meaning in life during the days around their commencement ceremony had higher trait levels of meaning in life one week following commencement. We discuss how making meaning of a poignant experience has implications for healthy psychological development. PMID:27688595

  19. Ainu as a Heritage Language of Japan: History, Current State and Future of Ainu Language Policy and Education

    ERIC Educational Resources Information Center

    Teeter, Jennifer Louise; Okazaki, Takayuki

    2011-01-01

    Ainu is the heritage language of the indigenous people of present-day southern Sakhalin, the Kurile Islands, present-day Hokkaido, and northeastern Honshu (mainland Japan). The UNESCO Interactive Atlas of the World's Languages in Danger (2009) considered the Ainu language critically endangered with only 15 speakers remaining. This article…

  20. National RCRA Hazardous Waste Biennial Report Data Files

    EPA Pesticide Factsheets

    The United States Environmental Protection Agency (EPA), in cooperation with the States, biennially collects information regarding the generation, management, and final disposition of hazardous wastes regulated under the Resource Conservation and Recovery Act of 1976 (RCRA), as amended. Collection, validation and verification of the Biennial Report (BR) data is the responsibility of RCRA authorized states and EPA regions. EPA does not modify the data reported by the states or regions. Any questions regarding the information reported for a RCRA handler should be directed to the state agency or region responsible for the BR data collection. BR data are collected every other year (odd-numbered years) and submitted in the following year. The BR data are used to support regulatory activities and provide basic statistics and trend of hazardous waste generation and management. BR data is available to the public through 3 mechanisms. 1. The RCRAInfo website includes data collected from 2001 to present-day (https://rcrainfo.epa.gov/rcrainfoweb/action/main-menu/view). Users of the RCRAInfo website can run queries and output reports for different data collection years at this site. All BR data collected from 2001 to present-day is stored in RCRAInfo, and is accessible through this website. 2. An FTP site allows users to access BR data files collected from 1999 - present day (ftp://ftp.epa.gov/rcrainfodata/). Zip files are available for download directly from this

  1. Assessing potential climate change pressures across the conterminous United States: mapping plant hardiness zones, heat zones, growing degree days, and cumulative drought severity throughout this century

    Treesearch

    Stephen N. Matthews; Louis R. Iverson; Matthew P. Peters; Anantha M. Prasad

    2018-01-01

    The maps and tables presented here represent potential variability of projected climate change across the conterminous United States during three 30-year periods in this century and emphasizes the importance of evaluating multiple signals of change across large spatial domains. Maps of growing degree days, plant hardiness zones, heat zones, and cumulative drought...

  2. The Effects of Binge Drinking on College Students’ Next-Day Academic Test-Taking Performance and Mood State

    PubMed Central

    Howland, Jonathan; Rohsenow, Damaris J; Greece, Jacey A; Littlefield, Caroline A; Almeida, Alissa; Heeren, Timothy; Winter, Michael; Bliss, Caleb A.; Hunt, Sarah; Hermos, John

    2010-01-01

    Aim To assess the effects of binge drinking on students’ next-day academic test-taking performance. Design A placebo-controlled cross-over design with randomly assigned order of conditions. Participants were randomized to either alcoholic beverage (mean =.12 g% breath alcohol concentration [BrAC]) or placebo on the first night and then received the other beverage a week later. The next day, participants were assessed on test-taking, neurocognitive performance and mood state. Participants 193 college students (≥ 21 years) recruited from greater Boston. Setting The trial was conducted at the General Clinical Research Center at the Boston Medical Center. Measurements The Graduate Record Exams © (GREs) and a quiz on a lecture presented the previous day measured test-taking performance; the Neurobehavioral Evaluation System (NES3) and the Psychomotor Vigilance Test (PVT) measured neurocognitive performance; and, the Profile of Mood States (POMS) measured mood. Findings Test-taking performance was not affected the morning after alcohol administration, but mood state and attention/reaction time were. Conclusion Drinking to a level of .12 g% BrAC does not affect next-day test-taking performance, but does affect some neurocognitive measures and mood state. PMID:20403018

  3. Day Care and Federal Funding: Current Problems and Possible Solutions.

    ERIC Educational Resources Information Center

    Dail, Paula W.

    The current policy of consolidating funding for all Title XX programs into block grants presents problems for day care users who increasingly must begin to explore alternatives to federally funded day care services. The block grants are problematic because they (1) are undesignated and can be used as the state wills, (2) have no matching fund…

  4. Solar Insights from the 2016 RPS Summit | State, Local, and Tribal

    Science.gov Websites

    been one of the most effective ways to advance solar and other clean energy technologies at the state educational two days of presentations, panels, group discussions and networking. Lori Bird, Principal Analyst at NREL's Market and Policy Impact Analysis Group, addresses the 2016 RPS Summit with a presentation

  5. Estimated Domestic, Irrigation, and Industrial Water Use in Washington, 2000

    USGS Publications Warehouse

    Lane, R.C.

    2004-01-01

    Since 1950, the U.S. Geological Survey has published a series of Circulars and other reports on the estimated use of water in the United States at 5-year intervals. This report presents State, regional, and county estimates of the amount of water used for domestic, irrigation, and industrial purposes in the State of Washington during the year 2000. Domestic water use was estimated to be 674 million gallons per day and the per-capita rate, 114 gallons per day. Crop-irrigation water use was estimated to be 3,005 million gallons per day and the application rate, 2.2 acre-feet per acre per year, or feet per year. Golf-course irrigation water use was estimated to be 23.6 million gallons per day and the application rate, 1.4 feet per year. Industrial water use was estimated to be 681 million gallons per day. Historically, these core categories account for about 92 percent of the estimated offstream water used in Washington.

  6. Two global conformation states of a novel NAD(P) reductase like protein of the thermogenic appendix of the Sauromatum guttatum inflorescence.

    PubMed

    Skubatz, Hanna; Howald, William N

    2013-06-01

    A novel NAD(P) reductase like protein (RL) belonging to a class of reductases involved in phenylpropanoid synthesis was previously purified to homogeneity from the Sauromatum guttatum appendix. The Sauromatum appendix raises its temperature above ambient temperature to ~30 °C on the day of inflorescence opening (D-day). Changes in the charge state distribution of the protein in electrospray ionization-mass spectrometry spectra were observed during the development of the appendix. RL adopted two conformations, state A (an extended state) that appeared before heat-production (D - 4 to D - 2), and state B (a compact state) that began appearing on D - 1 and reached a maximum on D-day. RL in healthy leaves of Arabidopsis is present in state A, whereas in thermogenic sporophylls of male cones of Encephalartos ferox is present in state B. These conformational changes strongly suggest an involvement of RL in heat-production. The biophysical properties of this protein are remarkable. It is self-assembled in aqueous solutions into micrometer sizes of organized morphologies. The assembly produces a broad range of cyclic and linear morphologies that resemble micelles, rods, lamellar micelles, as well as vesicles. The assemblies could also form network structures. RL molecules entangle with each other and formed branched, interconnected networks. These unusual assemblies suggest that RL is an oligomer, and its oligomerization can provide additional information needed for thermoregulation. We hypothesize that state A controls the plant basal temperature and state B allows a shift in the temperature set point to above ambient temperature.

  7. Rapid mixing and short storage timescale in the magma dynamics of a steady-state volcano

    NASA Astrophysics Data System (ADS)

    Petrone, Chiara Maria; Braschi, Eleonora; Francalanci, Lorella; Casalini, Martina; Tommasini, Simone

    2018-06-01

    Steady-state volcanic activity implies equilibrium between the rate of magma replenishment and eruption of compositionally homogeneous magmas, lasting for tens to thousands of years in an open conduit system. The Present-day activity of Stromboli volcano (Aeolian Islands, Southern Italy) has long been recognised as typical of a steady-state volcano, with a shallow magmatic reservoir (highly porphyritic or hp-magma) continuously refilled by more mafic magma (with low phenocryst content or lp-magma) at a constant rate and accompanied by mixing, crystallisation and eruption. Our aim is to clarify the timescale and dynamics of the plumbing system at the establishment of the Present-day steady-state activity (<1.2 ka) to pinpoint the onset of the steady-state regime. We investigated the Post-Pizzo (PP) pyroclastic sequence (∼1.7-1.5 ka) and one of the Early Paroxysms (EP) of the Present-day activity, focusing on the clinopyroxene population. Whole rock and clinopyroxene compositional variation among the PP and EP magmas is consistent with the time progression of the Stromboli system towards more mafic and lower 87Sr/86Sr compositions, pointing to the chemical and isotopic signature of the Present-day activity. Clinopyroxenes from both PP and EP record a complex history with compositional zoning that reflects growth in three different melt domains: a high-Mg# proto-lp recharging magma, a low-Mg# proto-hp resident magma, and a transient intermediate-Mg# magma. These are the result of complex turbulent flow fields and mixing regimes produced by repeated injections of the proto-lp magma in the shallow proto-hp magma reservoir. During the PP period the magmatic system was already able to regain the pre-input proto-hp composition, gradually changing toward a less evolved signature after the injection(s) of the more mafic proto-lp magma, owing to efficient (days to a few years) stirring and melt homogenisation (i.e., homogenisation time < residence time). Based upon Fe-Mg diffusion in clinopyroxene the total residence time during PP and EP periods, from the arrival of the mafic magma in the shallow system until the eruption, ranges from 1 to ∼50 years. Longer residence times (up to 150 years) have been recorded in the initial phase of the PP sequence, possibly testifying to the transition from a closed- to the open-conduit, steady-state regime of the Present-day activity. Some clinopyroxenes from the PP recorded the mafic triggering event of the feeding proto-lp magma occurring within few months to a few days before eruption. Remarkably, other clinopyroxene portions crystallised and captured the rapid timescales (a few days) of the on-going mixing and homogenisation process between the proto-lp and the proto-hp magmas leading to the eruption. The modelling of clinopyroxene zoning events at Stromboli provides evidence for growth and storage in three different melt domains, and sets robust constraints on their residence time from lp-magma recharge(s) to eruption, along with the timescales of melt homogenisation and triggering events. The lifetime history captured by Fe-Mg zoning of Stromboli clinopyroxenes suggests that the interplay between rapid mixing and short storage timescales can be a key parameter controlling the dynamics of the plumbing system of steady-state volcanoes.

  8. Developing Multicultural Awareness: An In-service Day Proposal for Rend Lake College, Ina, Illinois.

    ERIC Educational Resources Information Center

    Rust, Joseph Henry

    Noting that the state of Illinois mandates that community colleges address cultural diversity in their curriculum, this paper presents a proposal for a day-long in-service faculty education program to make faculty aware that cultural diversity exists at Rend Lake College (Illinois). The paper begins with a schedule for the in-service day, offering…

  9. Guidebook for School Administrators.

    ERIC Educational Resources Information Center

    Hess, Fritz, Ed.

    To provide guidance and advice regarding day-to-day responsibilities of new and experienced school administrators and superintendents in New York State, this compendium of knowledge and advice submitted by practitioners is presented with emphasis on all major aspects of superintendency. The section on general aspects of superintendency includes…

  10. Mass Communication in Mexico; Proceedings of the March 11-15, 1974 Seminar in Mexico, D.F.

    ERIC Educational Resources Information Center

    Hester, Albert L., Ed.; Cole, Richard R., Ed.

    These proceedings of the five-day seminar (the first meeting of the Interantional Communication Division outside the United States) contain almost 50 papers or oral presentations, plus introductions by the editors. Most papers and presentations deal in some way with Mexico or Latin America, with a few dealing with the United States. Contents are…

  11. Analysis of the United States Marine Corps’ Utilization of Defense Logistics Agency Disposition Services as a Source of Supply

    DTIC Science & Technology

    2011-12-03

    difficult within the DoD because “most incentives and motivations are not apparent for either government or industry ” (p. 84). Doane and Spencer (1997...stated that industry incentives and motivation seem to be based on the same profit and loss theories that were present before acquisition reform...purchased items needed for the unit’s day-to-day operations, such as digital cameras, commercial tactical clothing and eyewear , plasma televisions, lawn

  12. The Civilization Course, Then and Now.

    ERIC Educational Resources Information Center

    Hope, Quentin M.

    1986-01-01

    Courses on French civilization and culture should begin with a presentation of essential information, including historical background, role of the state, and the weight and presence of the past. They should move on through public life--politics, commerce, industry, social structures, the media--to the experiences of day-to-day life. (Author/JR)

  13. Annual State of Connecticut Obstetrics and Gynecology Resident Research Day.

    PubMed

    Seagle, Brandon-Luke L; Ballard, Jennifer; Kakar, Freshta; Panarelli, Erin; Samuelson, Robert; Shahabi, Shohreh

    2015-01-01

    To increase opportunities for Obstetrics and Gynecology(Ob/Gyn) residents to present their research, an Annual State of Connecticut Ob/Gyn Resident Research Day (RRD) was created. At the first annual RRD, 33 residents, representing five of six Connecticut Ob/Gyn residency programs, presented 39 poster and eight oral presentations. RRD evaluators rated the overall symposium and the quality of resident oral and poster presentations as either "excellent" or "above average." Residency program directors reported that the symposium was "very helpful" for evidencing resident scholarship as required by the Accreditation Council for Graduate Medical Education (ACGME). Surveyed residents reported that the symposium promoted their research and was a valuable investment of their time. An annual specialty-specific, statewide RRD was created, experienced good participation, and was well evaluated. The annual, statewide Ob/Gyn RRD may serve as a model for development of other specialty-specific, statewide RRD events.

  14. Problems with DNA

    ERIC Educational Resources Information Center

    Erickson, Keith A.; Franciszkowicz, Marc J.

    2010-01-01

    A modified version of this project was used during the final seven days of a year-long calculus sequence at the United States Military Academy to introduce students to the nature of integrative learning. Students from different majors were brought together in groups and spent the first few days going over the mathematics material presented here.…

  15. On Religious Subjects in School Education

    ERIC Educational Resources Information Center

    Rodionov, S. N.; Shevtsov, R. P.

    2008-01-01

    These days, problems of relations between the church and the schools are at the focus of attention of sociologists. In present-day Russia, religion, particularly the Orthodox religion, is acknowledged to have the right to contribute to the formation of the Russian state and culture. According to the findings of recent sociological surveys, many…

  16. Public/Private Partnership--A Cost Effective Model for Child Day Care Services.

    ERIC Educational Resources Information Center

    Alisberg, Helene R.

    Trends suggest that 11 million children in the United States will need day care services by 1995. Presently, corporations provide child care support through subsidies to low income employees or through community facilities, parent education, and information and referral (I & R) services. Such support results in reduced rates of absenteeism and…

  17. There's Rosemary for Remembrance.

    ERIC Educational Resources Information Center

    Keegan, John

    2000-01-01

    Presents a portrait of reverent remembrance of the war dead in England, noting that students in the United States need to learn that Memorial Day is more than just a fun 3-day holiday. Explains the importance of gardens, landscaping, and tradition to the English in remembering the soldiers who died fighting for their country and freedom. (SM)

  18. Summaries of the State-of-the-Art Position Papers on Day Care.

    ERIC Educational Resources Information Center

    Texas State Dept. of Public Welfare, Austin.

    This review consists of summaries of 20 position papers presenting varying viewpoints on aspects of the Federal Interagency Day Care Requirements (FIDCR). Among the authors represented are Gwen Morgan, Edward Zigler, Greta Fein, Henry Ricciuti, Urie Bronfenbrenner, Jerome Kagan and Elizabeth Prescott. Seven of the position papers deal with legal…

  19. Minimum Competency Testing Clarification Hearing (July 9th, 1981).

    ERIC Educational Resources Information Center

    National Inst. of Education (ED), Washington, DC.

    Barbara Jordan served as the hearing officer for three-day adversary evaluation hearings about the pros and cons of minimum competency testing (MCT). This report is the complete transcript of the second day of proceedings. The pro team, lead by James Popham, began by presenting representatives of four states (Florida, California, Texas, and…

  20. Nutrient Intakes: Individuals in 48 States, Year 1977-78. Nationwide Food Consumption Survey 1977-78. Report No. I-2.

    ERIC Educational Resources Information Center

    Department of Agriculture, Washington, DC.

    This report presents 3-day nutrient intake data for about 36,100 individuals in 48 states. Data are provided in 157 tables, and results are summarized in the text. The contribution of 14 food groups to intakes of food energy and 14 nutrients are presented. Also included are the average intakes of food energy and nutrients, the nutrient densities…

  1. Food Intakes: Individuals in 48 States, Year 1977-78. Nationwide Food Consumption Survey 1977-78. Report No. I-1.

    ERIC Educational Resources Information Center

    Human Nutrition Information Service (USDA), Hyattsville, MD.

    This report presents 3-day food intake data for about 36,l00 individuals in the 48 conterminous States. The information was collected from April 1977 through March 1978 in the Nationwide Food Consumption Survey conducted by the U.S. Department of Agriculture. Data on food intakes and characteristics of the sample are presented in 510 tables.…

  2. Foundations of the Islamic State: Management, Money, and Terror in Iraq, 2005-2010

    DTIC Science & Technology

    2016-01-01

    Foundations of the Islamic State Management, Money , and Terror in Iraq, 2005–2010 Patrick B. Johnston, Jacob N. Shapiro, Howard J. Shatz...needed basis. • ISI fundraising aimed to raise money locally, largely from crimi- nal activities but also partly from activities that resembled state...action, such as taxation. As with the present-day Islamic State, ISI demonstrated sophisticated financial management, efficiently reallocating money

  3. Hybrid Practices Meet Nation-State Language Policies: Transcarpathia in the Twentieth Century and Today

    ERIC Educational Resources Information Center

    Csernicskó, István; Laihonen, Petteri

    2016-01-01

    From the early twentieth century to the present day, Transcarpathia has belonged to several states: the Austrian-Hungarian Monarchy, Czechoslovakia, the Hungarian Kingdom, the Soviet Union, and finally to Ukraine. The status of what counts as a minority and a majority language has changed each time the state affiliation has been changed. Based on…

  4. ASSESSING WATER QUALITY CHANGES IN THE LAKES OF THE NORTHEASTERN UNITED STATES USING SEDIMENT DIATOMS

    EPA Science Inventory

    Diatom assemblages were selected as indicators of lake condition and to assess historical lake water quality changes in 257 lakes in the northeastern United States. The "top" (surface sediments, present-day) and "bottom" (generally from >30 cm deep, representing historical condit...

  5. The Protolysis of Singlet Excited B-Naphtol.

    ERIC Educational Resources Information Center

    van Stam, Jan; Lofroth, Jan-Erik

    1986-01-01

    Presents a two-day experiment to estimate the pK for the protolysis of beta-naphtol in its ground state and the first singlet excited state. Results are compared to results obtained from the integrated rate equations in which values of the rate constants were taken from a time-resolved study. (JN)

  6. Exercise and sleep predict personal resources in employees' daily lives.

    PubMed

    Nägel, Inga J; Sonnentag, Sabine

    2013-11-01

    The present study investigates the interaction of exercise and sleep on state-like personal resources in employees' daily lives. Further, the study examines the association between state-like personal resources and emotional exhaustion. We conducted a diary study over five consecutive working days (total of 443 days) with 144 employees who answered daily online surveys after work and before bedtime. Multilevel modeling showed that exercise after work was positively related to the next day's personal resources when sleep duration during the night time was longer compared to other nights. Furthermore, personal resources positively related to lower emotional exhaustion after work on the next day. This study demonstrates that exercise and sleep may help to renew personal resources. Results stress the importance of balancing exercise and sleep in daily life. © 2013 The International Association of Applied Psychology.

  7. The Oxytocin Receptor Gene (OXTR) in Relation to State Levels of Loneliness in Adolescence: Evidence for Micro-Level Gene-Environment Interactions

    PubMed Central

    van Roekel, Eeske; Verhagen, Maaike; Scholte, Ron H. J.; Kleinjan, Marloes; Goossens, Luc; Engels, Rutger C. M. E.

    2013-01-01

    Previous research has shown that the rs53576 variant of the oxytocin receptor gene (OXTR) is associated with trait levels of loneliness, but results are inconsistent. The aim of the present study is to examine micro-level effects of the OXTR rs53576 variant on state levels of loneliness in early adolescents. In addition, gene-environment interactions are examined between this OXTR variant and positive and negative perceptions of company. Data were collected in 278 adolescents (58% girls), by means of the Experience Sampling Method (ESM). Sampling periods consisted of six days with nine assessments per day. A relation was found between the OXTR rs53576 variant and state loneliness, in girls only. Girls carrying an A allele had higher levels of state loneliness than girls carrying the GG genotype. In addition, adolescents with an A allele were more affected by negative perceptions of company than GG carriers, on weekend days only. No significant gene-environment interactions were found with positive company. Adolescents carrying an A allele were more susceptible to negative environments during weekend days than GG carriers. Our findings emphasize the importance of operationalizing the phenotype and the environment accurately. PMID:24223720

  8. The oxytocin receptor gene (OXTR) in relation to state levels of loneliness in adolescence: evidence for micro-level gene-environment interactions.

    PubMed

    van Roekel, Eeske; Verhagen, Maaike; Scholte, Ron H J; Kleinjan, Marloes; Goossens, Luc; Engels, Rutger C M E

    2013-01-01

    Previous research has shown that the rs53576 variant of the oxytocin receptor gene (OXTR) is associated with trait levels of loneliness, but results are inconsistent. The aim of the present study is to examine micro-level effects of the OXTR rs53576 variant on state levels of loneliness in early adolescents. In addition, gene-environment interactions are examined between this OXTR variant and positive and negative perceptions of company. Data were collected in 278 adolescents (58% girls), by means of the Experience Sampling Method (ESM). Sampling periods consisted of six days with nine assessments per day. A relation was found between the OXTR rs53576 variant and state loneliness, in girls only. Girls carrying an A allele had higher levels of state loneliness than girls carrying the GG genotype. In addition, adolescents with an A allele were more affected by negative perceptions of company than GG carriers, on weekend days only. No significant gene-environment interactions were found with positive company. Adolescents carrying an A allele were more susceptible to negative environments during weekend days than GG carriers. Our findings emphasize the importance of operationalizing the phenotype and the environment accurately.

  9. Practitioners' Self-Evaluations of Contrasting Types of Professional Development

    ERIC Educational Resources Information Center

    Dunst, Carl J.; Raab, Melinda

    2010-01-01

    The effects of three types of in-service training on practitioners' self-evaluations of evidence-based preschool classroom practices were evaluated in a study of 255 participants from 26 states. Participants attended either conference presentations or 1-day or 2- to 3-day workshops or received one of two types of intensive in-service training…

  10. “I Think They All Felt Distressed!” Talking about Complex Issues in Early Childhood

    ERIC Educational Resources Information Center

    Bentley, Dana; Reppucci, Anthony

    2013-01-01

    The Thanksgiving Day holiday celebrated in the United States is generally traced to a first harvest celebration in the newly established Plymouth colony (present-day Massachusetts). Traditional storytelling describes the first Thanksgiving feast as having been attended by 53 Pilgrims (the European settlers) and 90 Native Americans. The holiday can…

  11. "ONCE UPON A DAY," A SERIES OF VIDEOTAPED TELEVISION PROGRAMS FOR CHILDREN.

    ERIC Educational Resources Information Center

    NATHANSON, NORBERT H.

    THIS BOOKLET DESCRIBES "ONCE UPON A DAY," AN EDUCATIONAL TELEVISION SERIES FOR CHILDREN AGED 4 TO 7. THE PROGRAM IS AVAILABLE AT NO COST TO ALL NEW YORK STATE EDUCATIONAL TELEVISION STATIONS, CLOSED CIRCUIT AND 2500 MEGACYCLES AND COMMUNITY ANTENNA SYSTEMS SERVING NEW YORK SCHOOLS. THE PROGRAM PRESENTS USEFUL CONCEPTS AND INFORMATION IN…

  12. Breaking Barriers: An Asian-American Curriculum Unit.

    ERIC Educational Resources Information Center

    Brombach, Catherine; Tice, Natasha Florey

    A 10-day curriculum is presented for upper elementary grades to explore who is in power on the local, state, and federal levels; and to investigate why so few Asian Americans are in power; and to confront personal prejudices and break stereotypes about Asian Americans. The 10 days are devoted to the following: (1) distinguishing between prejudice…

  13. Roll Call Questions To Enhance In-Class Presentations.

    ERIC Educational Resources Information Center

    Wiethoff, Carolyn

    This paper outlines an activity which is designed to make students comfortable speaking in the classroom environment. The paper states that, used properly, the activity is also an introduction to each day's course topic, and it encourages students to think about and report their own life experiences that illustrate a core construct from the day's…

  14. "Getting It": Sociolinguistic Research and the Teaching on U.S. Spanish

    ERIC Educational Resources Information Center

    Velázquez, Isabel

    2013-01-01

    This article presents the results of an analysis of student perceptions about speakers of Spanish in the United States before and after participation in a university course on U.S. Spanish that incorporates a hands-on research component. Three arguments are made here: That these perceptions influence their day-to-day relationship with bilingual…

  15. The increasing efficiency of tornado days in the United States

    NASA Astrophysics Data System (ADS)

    Elsner, James B.; Elsner, Svetoslava C.; Jagger, Thomas H.

    2015-08-01

    The authors analyze the historical record of tornado reports in the United States and find evidence for changes in tornado climatology possibly related to global warming. They do this by examining the annual number of days with many tornadoes and the ratio of these days to days with at least one tornado and by examining the annual proportion of tornadoes occurring on days with many tornadoes. Additional evidence of a changing tornado climate is presented by considering tornadoes in geographic clusters and by analyzing the density of tornadoes within the clusters. There is a consistent decrease in the number of days with at least one tornado at the same time as an increase in the number of days with many tornadoes. These changes are interpreted as an increasing proportion of tornadoes occurring on days with many tornadoes. Coincident with these temporal changes are increases in tornado density as defined by the number of tornadoes per area. Trends are insensitive to the begin year of the analysis. The bottom line is that the risk of big tornado days featuring densely concentrated tornado outbreaks is on the rise. The results are broadly consistent with numerical modeling studies that project increases in convective energy within the tornado environment.

  16. The Potsdam Parallel Ice Sheet Model (PISM-PIK) - Part 2: Dynamic equilibrium simulation of the Antarctic ice sheet

    NASA Astrophysics Data System (ADS)

    Martin, M. A.; Winkelmann, R.; Haseloff, M.; Albrecht, T.; Bueler, E.; Khroulev, C.; Levermann, A.

    2010-08-01

    We present a dynamic equilibrium simulation of the ice sheet-shelf system on Antarctica with the Potsdam Parallel Ice Sheet Model (PISM-PIK). The simulation is initialized with present-day conditions for topography and ice thickness and then run to steady state with constant present-day surface mass balance. Surface temperature and basal melt distribution are parameterized. Grounding lines and calving fronts are free to evolve, and their modeled equilibrium state is compared to observational data. A physically-motivated dynamic calving law based on horizontal spreading rates allows for realistic calving fronts for various types of shelves. Steady-state dynamics including surface velocity and ice flux are analyzed for whole Antarctica and the Ronne-Filchner and Ross ice shelf areas in particular. The results show that the different flow regimes in sheet and shelves, and the transition zone between them, are captured reasonably well, supporting the approach of superposition of SIA and SSA for the representation of fast motion of grounded ice. This approach also leads to a natural emergence of streams in this new 3-D marine ice sheet model.

  17. Toward Equity for Blacks in Higher Education.

    ERIC Educational Resources Information Center

    Lyons, Charles A.

    The present condition of the United States regarding the education of black college-age youth and the status of historically black colleges is discussed in this paper. Background information on the role of black colleges and an elaboration of present-day problems facing black colleges are presented. The declining enrollment, drop-out rate, counter…

  18. Manipulating affective state using extended picture presentations.

    PubMed

    Sutton, S K; Davidson, R J; Donzella, B; Irwin, W; Dottl, D A

    1997-03-01

    Separate, extended series of positive, negative, and neutral pictures were presented to 24 (12 men, 12 women) undergraduates. Each series was presented on a different day, with full counterbalancing of presentation orders. Affective state was measured using (a) orbicularis oculi activity in response to acoustic startle probes during picture presentation, (b) corrugator supercilii activity between and during picture presentation, and (c) changes in self-reports of positive and negative affect. Participants exhibited larger eyeblink reflex magnitudes when viewing negative than when viewing positive pictures. Corrugator activity was also greater during the negative than during the positive picture set, during both picture presentation and the period between pictures. Self-reports of negative affect increased in response to the negative picture set, and self-reports of positive affect were greatest following the positive picture set. These findings suggest that extended picture presentation is an effective method of manipulating affective state and further highlight the utility of startle probe and facial electromyographic measures in providing on-line readouts of affective state.

  19. Population Growth in the 1990s: Patterns within the United States.

    ERIC Educational Resources Information Center

    Perry, Marc

    2002-01-01

    Examines population growth during the 1990s for a variety of geographic levels including regions, divisions, states, metropolitan areas, counties, and large cities. Compares growth rates for the 1990s with earlier decades to provide an historical context for present-day trends in population growth and decline. Discusses how differential population…

  20. Infusing Commodity Marketing into the Agriculture Curriculum. Final Report.

    ERIC Educational Resources Information Center

    Northeast Arkansas Educational Cooperative, Strawberry.

    A project was conducted in Arkansas to infuse commodity marketing content into the agriculture curriculum. Thirty-three schools were selected to participate in the program; teachers from those schools attended a 2-day inservice program presented by a state coordinator for the project. The state coordinator also provided supervision and technical…

  1. Military Day Care: Problems and Perspective.

    ERIC Educational Resources Information Center

    Corey, George D.

    This paper presents some legal and social policy aspects of military child care facilities in the United States. Under the jurisdiction of Article I of the United States Constitution, the federal government has the right to determine the social welfare rights of people living on military installations; yet these people are not included in programs…

  2. STS-107 Flight Day 5 Highlights

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The fifth day of the STS-107 space mission begins with a presentation of The Six Space Technology and Research Students (STARS) program experiments aboard the Space Shuttle Columbia. Students from Australia, China, Israel, Japan, Lichtenstein and The United States send scientific experiments into space. The video includes the progress of experiments with various insects including silkworms, carpenter bees, ants, fish, and spiders.

  3. Establishing Systemic Social and Emotional Learning Approaches in Schools: A Framework for Schoolwide Implementation

    ERIC Educational Resources Information Center

    Oberle, Eva; Domitrovich, Celene E.; Meyers, Duncan C.; Weissberg, Roger P.

    2016-01-01

    Social and emotional learning (SEL) is a fundamental part of education. Incorporating high-quality SEL programming into day-to-day classroom and school practices has emerged as a main goal for many practitioners over the past decade. The present article overviews the current state of SEL research and practice, with a particular focus on the United…

  4. The oxidation state of Hadean magmas and implications for early Earth's atmosphere.

    PubMed

    Trail, Dustin; Watson, E Bruce; Tailby, Nicholas D

    2011-11-30

    Magmatic outgassing of volatiles from Earth's interior probably played a critical part in determining the composition of the earliest atmosphere, more than 4,000 million years (Myr) ago. Given an elemental inventory of hydrogen, carbon, nitrogen, oxygen and sulphur, the identity of molecular species in gaseous volcanic emanations depends critically on the pressure (fugacity) of oxygen. Reduced melts having oxygen fugacities close to that defined by the iron-wüstite buffer would yield volatile species such as CH(4), H(2), H(2)S, NH(3) and CO, whereas melts close to the fayalite-magnetite-quartz buffer would be similar to present-day conditions and would be dominated by H(2)O, CO(2), SO(2) and N(2) (refs 1-4). Direct constraints on the oxidation state of terrestrial magmas before 3,850 Myr before present (that is, the Hadean eon) are tenuous because the rock record is sparse or absent. Samples from this earliest period of Earth's history are limited to igneous detrital zircons that pre-date the known rock record, with ages approaching ∼4,400 Myr (refs 5-8). Here we report a redox-sensitive calibration to determine the oxidation state of Hadean magmatic melts that is based on the incorporation of cerium into zircon crystals. We find that the melts have average oxygen fugacities that are consistent with an oxidation state defined by the fayalite-magnetite-quartz buffer, similar to present-day conditions. Moreover, selected Hadean zircons (having chemical characteristics consistent with crystallization specifically from mantle-derived melts) suggest oxygen fugacities similar to those of Archaean and present-day mantle-derived lavas as early as ∼4,350 Myr before present. These results suggest that outgassing of Earth's interior later than ∼200 Myr into the history of Solar System formation would not have resulted in a reducing atmosphere.

  5. [Psychiatry during National Socialism: historical knowledge, implications for present day ethical debates].

    PubMed

    Roelcke, V

    2010-11-01

    This contribution is a synthesis of the results of historical research on psychiatry during the Nazi period and some implications for present day debates in medical ethics. The focus is on three issues: the relationship between physicians and the state, the impact of eugenically and economically motivated health and social policies for psychiatry (e.g. forced sterilization, patient killing/euthanasia) and psychiatric research. Three myths are deconstructed: 1) that medical atrocities were imposed from above by Nazi politicians on apolitical physicians, 2) that mass sterilization and patient killing had nothing to do with contemporary state of the art of medical reasoning and practice and 3) that ethically unacceptable research on psychiatric patients had nothing to do with the contemporary state of the art of biomedical sciences. It is argued that the findings on these issues of Nazi medicine are not specific to Germany and the period between 1933 and 1945 but they were the extreme manifestations of some potential problems implicit in modern medicine in general.

  6. Multiple Climate States of Habitable Exoplanets: The Role of Obliquity and Irradiance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kilic, C.; Raible, C. C.; Stocker, T. F., E-mail: stocker@climate.unibe.ch

    Stable, steady climate states on an Earth-size planet with no continents are determined as a function of the tilt of the planet’s rotation axis (obliquity) and stellar irradiance. Using a general circulation model of the atmosphere coupled to a slab ocean and a thermodynamic sea ice model, two states, the Aquaplanet and the Cryoplanet, are found for high and low stellar irradiance, respectively. In addition, four stable states with seasonally and perennially open water are discovered if comprehensively exploring a parameter space of obliquity from 0° to 90° and stellar irradiance from 70% to 135% of the present-day solar constant.more » Within 11% of today’s solar irradiance, we find a rich structure of stable states that extends the area of habitability considerably. For the same set of parameters, different stable states result if simulations are initialized from an aquaplanet or a cryoplanet state. This demonstrates the possibility of multiple equilibria, hysteresis, and potentially rapid climate change in response to small changes in the orbital parameters. The dynamics of the atmosphere of an aquaplanet or a cryoplanet state is investigated for similar values of obliquity and stellar irradiance. The atmospheric circulation substantially differs in the two states owing to the relative strength of the primary drivers of the meridional transport of heat and momentum. At 90° obliquity and present-day solar constant, the atmospheric dynamics of an Aquaplanet state and one with an equatorial ice cover is analyzed.« less

  7. Multiple Climate States of Habitable Exoplanets: The Role of Obliquity and Irradiance

    NASA Astrophysics Data System (ADS)

    Kilic, C.; Raible, C. C.; Stocker, T. F.

    2017-08-01

    Stable, steady climate states on an Earth-size planet with no continents are determined as a function of the tilt of the planet’s rotation axis (obliquity) and stellar irradiance. Using a general circulation model of the atmosphere coupled to a slab ocean and a thermodynamic sea ice model, two states, the Aquaplanet and the Cryoplanet, are found for high and low stellar irradiance, respectively. In addition, four stable states with seasonally and perennially open water are discovered if comprehensively exploring a parameter space of obliquity from 0° to 90° and stellar irradiance from 70% to 135% of the present-day solar constant. Within 11% of today’s solar irradiance, we find a rich structure of stable states that extends the area of habitability considerably. For the same set of parameters, different stable states result if simulations are initialized from an aquaplanet or a cryoplanet state. This demonstrates the possibility of multiple equilibria, hysteresis, and potentially rapid climate change in response to small changes in the orbital parameters. The dynamics of the atmosphere of an aquaplanet or a cryoplanet state is investigated for similar values of obliquity and stellar irradiance. The atmospheric circulation substantially differs in the two states owing to the relative strength of the primary drivers of the meridional transport of heat and momentum. At 90° obliquity and present-day solar constant, the atmospheric dynamics of an Aquaplanet state and one with an equatorial ice cover is analyzed.

  8. Quantum Communication without Alignment using Multiple-Qubit Single-Photon States

    NASA Astrophysics Data System (ADS)

    Aolita, L.; Walborn, S. P.

    2007-03-01

    We propose a scheme for encoding logical qubits in a subspace protected against collective rotations around the propagation axis using the polarization and transverse spatial degrees of freedom of single photons. This encoding allows for quantum key distribution without the need of a shared reference frame. We present methods to generate entangled states of two logical qubits using present day down-conversion sources and linear optics, and show that the application of these entangled logical states to quantum information schemes allows for alignment-free tests of Bell’s inequalities, quantum dense coding, and quantum teleportation.

  9. Selective CRF2 receptor agonists ameliorate the anxiety- and depression-like state developed during chronic nicotine treatment and consequent acute withdrawal in mice.

    PubMed

    Bagosi, Zsolt; Palotai, Miklós; Simon, Balázs; Bokor, Péter; Buzás, András; Balangó, Beáta; Pintér, Dávid; Jászberényi, Miklós; Csabafi, Krisztina; Szabó, Gyula

    2016-12-01

    The aim of the present study was to investigate the effects of the selective agonists of the corticotropin-releasing factor (CRF) 2 receptor, urocortin 2 (UCN 2) and urocortin 3 (UCN 3), on the anxiety- and depression-like signs induced by acute nicotine withdrawal in mice. In order to do so, male CFLP mice were exposed for 7 days to repeated intraperitoneal (IP) injection with nicotine or saline solution and 1day of acute withdrawal and then a single intracerebroventricular (ICV) injection with UCN 2, UCN 3 or saline solution. After 30min the mice were observed in an elevated plus-maze test or a forced swim test, for anxiety- and depression-like behavior. After 5min of testing, the plasma corticosterone concentration reflecting the activity of the hypothalamic-pituitary-adrenal (HPA) axis was also determined by a chemo-fluorescent method. Half of the animals were treated ICV and evaluated on the 8th day, the other half on the 9th day. On the 8th day, nicotine-treated mice presented signs of anxiolysis and depression, but no significant elevation of the plasma corticosterone concentration. On the 9th day, nicotine-treated mice exhibited signs of anxiety and depression and a significant increase of the plasma corticosterone levels. Central administration of UCN 2 or UCN 3 ameliorated the anxiety- and depression-like state including the hyperactivity of the HPA axis, developed during acute withdrawal following chronic nicotine treatment. The present study suggests that selective CRF2 receptor agonists could be used as a therapy in nicotine addiction. Copyright © 2016 Elsevier B.V. All rights reserved.

  10. A Vote for Election Science as an Academic Discipline

    ERIC Educational Resources Information Center

    Foster, Andrea L.

    2006-01-01

    This article presents the suggestion of Merle S. King, chairman of the department of computer science and information systems at Kennesaw State University and also a director of Kennesaw State's Center for Elections Systems, which has helped establish a uniform statewide voting system in Georgia. On the last day of the conference sponsored by the…

  11. 76 FR 43963 - Regional Haze State Implementation Plan; State of Nevada; Extension of Comment Period

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-22

    ... deadline for written comments on the proposed approval of the Regional Haze SIP by 30 days to August 22... technical materials that form the basis of Nevada's Regional Haze SIP and EPA's proposed approval. The EPA...'s proposed approval of the technical analyses presented in Nevada's plan. DATES: The comment period...

  12. The New York State Teacher. The Metropolitan Life Survey.

    ERIC Educational Resources Information Center

    Harris (Louis) and Associates, Inc., New York, NY.

    Results are presented of a survey of 500 teachers in New York who were asked their opinions on public education in the state. A summary of findings provides information about teachers' opinions on: (1) emphasis on basic skills; (2) school discipline and safety; (3) extension of school day or year; (4) teacher apprenticeships; (5) career ladders…

  13. Struggle and Success: The State of Teacher Education at Tribal Colleges and Universities

    ERIC Educational Resources Information Center

    Lamb, Carmelita

    2016-01-01

    From the earliest partnerships between Tribal Colleges and Universities (TCUs) and state colleges and universities, to the present-day independent bachelor's and master's degree teacher education programs, there has been a change in how higher education is designed to meet the uniquely Indigenous way that knowledge is exchanged, leading to greater…

  14. Users report for the Northern Great Plains.

    NASA Technical Reports Server (NTRS)

    Waltz, F. A.; Myers, V. I.; Heinemann, L. R.

    1973-01-01

    The applications of remote-sensing techniques offer new approaches to many of the present-day problems encountered by various state agencies in South Dakota. The study was completed in three phases. The first report presented the information needs of the state agencies and educational efforts; the second defined the data handling procedures for fulfilling the applications; and the third phase was a development of a dynamic information dissemination plan on a state-wide basis. Aircraft data, satellite imagery, and other remotely sensed information are valuable for decision-making processes. A design for an organization to acquire for the state the advantages of remote-sensing systems for resources research and management has been developed.

  15. The effects of partner togetherness on salivary testosterone in women in long distance relationships

    PubMed Central

    Hamilton, Lisa Dawn; Meston, Cindy M.

    2009-01-01

    The present study examined whether testosterone levels are influenced by being with a sexual and romantic partner after a period of sexual abstinence. Women in long distance relationships (n = 15) provided five saliva samples: at least one week before seeing their partner (and at least 2 weeks since their last visit), the day before seeing their partner, when they were with their partner but prior to engaging in sexual activity, the day after their first sexual activity, and three days after they were separated from their partners. Salivary testosterone was lowest when participants had been away from their partners for at least two weeks and highest the day before they were to see their partners and the day after sexual activity. Results from this study indicated that women’s testosterone increased both the day before they were with their partners and they day after they first engaged in sexual activity. However, something about initially reuniting with their partners returned their testosterone to baseline levels, which may be an effect of being in the same location as a partner, or just a state fluctuation due to nervousness or other psychological state. PMID:19900454

  16. The effects of partner togetherness on salivary testosterone in women in long distance relationships.

    PubMed

    Hamilton, Lisa Dawn; Meston, Cindy M

    2010-02-01

    The present study examined whether women's testosterone levels are influenced by being with a sexual and romantic partner after a period of sexual abstinence. Women in long distance relationships (n=15) provided five saliva samples: at least 1 week before seeing their partner (and at least 2 weeks since their last visit), the day before seeing their partner, when they were with their partner but prior to engaging in sexual activity, the day after their first sexual activity, and 3 days after they were separated from their partners. Salivary testosterone was lowest when participants had been away from their partners for at least 2 weeks and highest the day before they were to see their partners and the day after sexual activity. Results from this study indicated that women's testosterone increased both the day before they were with their partners and they day after they first engaged in sexual activity. However, something about initially reuniting with their partners returned their testosterone to baseline levels, which may be an effect of being in the same location as a partner, or just a state fluctuation due to nervousness or other psychological state. Copyright 2009 Elsevier Inc. All rights reserved.

  17. A Multidisciplinary Science Summer Camp for Students with Emphasis on Environmental and Analytical Chemistry

    ERIC Educational Resources Information Center

    Schwarz, Gunnar; Frenzel, Wolfgang; Richter, Wolfgang M.; Ta¨uscher, Lothar; Kubsch, Georg

    2016-01-01

    This paper presents the course of events of a five-day summer camp on environmental chemistry with high emphasis on chemical analysis. The annual camp was optional and open for students of all disciplines and levels. The duration of the summer camp was five and a half days in the Feldberg Lake District in northeast Germany (federal state of…

  18. Updated outdoor recreation use values on national forests and other public lands.

    Treesearch

    John Loomis

    2005-01-01

    This report summarizes more than 30 years of the literature on net economic value of outdoor recreation on public lands. The report provides average net willingness to pay or consumer surplus per day for 30 recreation activities at the national level. Values per day by recreation activity are also presented by census region of the United States. Detailed tables provide...

  19. Day Care in Vermont: An Evaluation of the Vermont Model FAP Child Care Service System.

    ERIC Educational Resources Information Center

    Siedman, Eileen

    This book presents an extensive examination of the organization and operation of the Vermont model day care delivery system which was designed in the context of the proposed Family Assistance Plan (FAP). The model tested the ability of Federal and State employees to work together and share resources in designing a new approach to welfare reform.…

  20. Effect of re-feeding after starvation on biomechanical properties in rat small intestine.

    PubMed

    Dou, Y; Gregersen, S; Zhao, J; Zhuang, F; Gregersen, H

    2001-10-01

    Luminal nutrients are essential for maintaining the structural and functional integrity of the gut. Starvation induces pronounced structural and biomechanical remodelling in the rat small intestine. The present work was done to study the recovery process after resumption of food intake. Twenty-five Wistar rats were allocated to five groups. Four groups fasted for 7 days but had free access to water. One of these groups served as fasted controls and was killed at the end of the fast. The other three groups were re-fed for 2, 4 and 7 days before they were euthanised. The fifth group had free access to food during the whole study (fed controls). The intestinal no-load state, zero-stress state and the stress-strain relationship during distension were studied. The intestinal segments were cut transversely into a series of short ring-shaped segments to obtain the no-load state. Each ring was cut in the radial direction to obtain the zero-stress state. The rats regained the lost body weight (22%) by the 7th day of re-feeding. The lost duodenal mass (40%) and jejunal mass (25%) were regained by the 2nd day whereas the lost mass from ileum (18%) was regained by the 4th day. The fasting-induced morphometric changes were normalised by re-feeding on the 2nd day in the duodenum and jejunum, and on the 4th day in the ileum. The longitudinal stress-strain curves shifted to the right after fasting and shifted back within two days following re-feeding (P<0.05). The circumferential stress-strain curves in the fasted or re-fed rats changed in a similar though less pronounced way. Normal values were reached within 4-7 days for the circumferential direction. In conclusion, fasting-induced biomechanical and structural remodelling were normalised by re-feeding in a time- and location-dependent way.

  1. The Potsdam Parallel Ice Sheet Model (PISM-PIK) - Part 2: Dynamic equilibrium simulation of the Antarctic ice sheet

    NASA Astrophysics Data System (ADS)

    Martin, M. A.; Winkelmann, R.; Haseloff, M.; Albrecht, T.; Bueler, E.; Khroulev, C.; Levermann, A.

    2011-09-01

    We present a dynamic equilibrium simulation of the ice sheet-shelf system on Antarctica with the Potsdam Parallel Ice Sheet Model (PISM-PIK). The simulation is initialized with present-day conditions for bed topography and ice thickness and then run to steady state with constant present-day surface mass balance. Surface temperature and sub-shelf basal melt distribution are parameterized. Grounding lines and calving fronts are free to evolve, and their modeled equilibrium state is compared to observational data. A physically-motivated calving law based on horizontal spreading rates allows for realistic calving fronts for various types of shelves. Steady-state dynamics including surface velocity and ice flux are analyzed for whole Antarctica and the Ronne-Filchner and Ross ice shelf areas in particular. The results show that the different flow regimes in sheet and shelves, and the transition zone between them, are captured reasonably well, supporting the approach of superposition of SIA and SSA for the representation of fast motion of grounded ice. This approach also leads to a natural emergence of sliding-dominated flow in stream-like features in this new 3-D marine ice sheet model.

  2. The Presentation of Germany in Israeli History Textbooks between 1948 and 2014

    ERIC Educational Resources Information Center

    Kizel, Arie

    2015-01-01

    This article reviews an extensive study of Israeli secondary school general history curricula and textbooks since the establishment of the state in 1948 until the present day. By analyzing the way in which Germany is presented in various contexts, the findings of the study indicate that, while the textbooks reflect a shift from an early censorious…

  3. Re-Bordering Comparative Education in Latin America: Between Global Limits and Local Characteristics

    ERIC Educational Resources Information Center

    Acosta, Felicitas; Perez Centeno, Cristian G.

    2011-01-01

    Conceived for presentation at the XIV WCCES conference in Istanbul in 2010, the topic of which was "Bordering Comparative Education", this paper, within that framework, aims to present the current state of the discipline in Latin America in relation to a quick overview of its present-day situation at a global level. After providing an…

  4. Present-day vertical deformation of the Cascadia margin, Pacific Northwest, United States

    NASA Astrophysics Data System (ADS)

    Mitchell, Clifton E.; Vincent, Paul; Weldon, Ray J., III; Richards, Mark A.

    1994-06-01

    We estimate present-day uplift rates along hte Cascadia Subduction Zone in California, Oregon, and Washington in the Pacific Northwest, United States, by utilizing repeated leveling surveys and tide guage records. These two independent data sets give similar profiles for latitudinal variation of contemporary uplift rates along the coast. Uplift rates are extended inland through east-west leveling lines that connect the north-south line along hte coast to the north-south line along the inland valleys just west of the Cascades. The results are summarized as a contour map of present day uplift rates for the western Pacific Northwest. We find that rates of present day uplift vary latitudinally along the coast to the inland valleys. Long-term tial records of Neah Bay, Astoria, and Crescent City indicate uplift of land relative to sea level of 1.6 +/- 0.2, 0.0 +/- 0.2, 0.9 +/- 0.2 mm/yr, respectively (+/- 1 standard error). Unlike previous estimates of relative sea level change at Astoria, we adjust for discharge effects of the Columbia River, including human managment influences. After approximating an absolute framework by using 1.8 +/- 0.1 mm/yr to compensate for global sea level rise, results indicate that much of the western Pacific Northwest is rising at rates between 0 and 5 mm/ur. The most rapid uplift rates are near the coast, particularly near the Olympic Peninsula, the mouth of the Columbia River, Cape Blanco, and Cape Mendocino. Two axes of uplift are identified: one trends northeast from the southwest Oregon coast, and the other strends south-southeasterly from the Olympic Peninsula to the Columbia River. The Puget Sound vicinity and a small east-west region from the north cnetral Oregon coast ot he inland Willamette Valley are subiding at rates up to 1 mm/ur. We interpret the overall pattern of rapid present day uplift to be generated by interseismic strain accumulation in the subduction zone. This interseismic elastic strain accumulation implies significant seismic hazard.

  5. A Study of Pulse Shape Evolution and X-Ray Reprocessing in Her X-1

    NASA Technical Reports Server (NTRS)

    Cushman, Paula P.

    1998-01-01

    This study focused on the pulse shape evolution and spectral properties of the X-ray binary Her X-1 with regard to the well known 35-day cycle of Her X-1. A follow-up set of RXTE observations has been conducted in RXTE AO-2 phase and the two observation sets are being analyzed together. We presented results of early analysis of pulse shape evolution in "Proceedings of the Fourth Compton Symposium". More advanced analysis was presented at the HEAD meeting in November, 1997 in Estes Park, Colorado. A related study of the 35-day cycle using RXTE/ASM data, which laid out the overall picture within which the more detailed PCA observations could be placed has also been conducted. The results of this study have been published. A pair of papers on the detailed pulse evolution and the spectral/color evolution are currently being prepared for publication. Some of the significant results of this study have been a confirmation of the detailed pulse profile changes at the end of the Main High state in HerX-1 first observed by GINGA, observations of the pulse evolution in several Short High states which agree with the pulse evolution pattern predicted using a disk occultation model, observation of a systematic lengthening of the eclipse egress during the Main High state of the 35-day phase and observation of a new type of extended eclipse ingress during which pulsations cease to observed during the Short High state.

  6. 78 FR 4138 - Chief of Engineers Environmental Advisory Board; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ... ``Caf[eacute] Conference Room'' on the second floor of the Sandra Day O'Connor United States Courthouse... presentations during this meeting will focus on energy and water security and sustainability, and flow...

  7. Jose de Escandon--Colonizer of Nuevo Santander.

    ERIC Educational Resources Information Center

    Miller, Hubert J.

    Jose de Escandon's colonization work in the present Mexican state of Tamaulipas and the lower Rio Grande valley forms an essential part of the Spanish northern borderlands. Many of the land grants in the area, ranching, and some of the present day agricultural industries originated with the colonization projects initiated by Escandon, who proved…

  8. Entanglement in General Multipartite Quantum Systems and Its Role in Quantum Information Processing Tasks

    NASA Astrophysics Data System (ADS)

    Gielerak, Roman

    A major role playing by entanglement of quantum states in several, present day applications of genuine quantum technologies is briefly reviewed. Additionally, the notion and classification of multipartite entanglement has been presented. A new, monotone under (S)LOCC-operations measures of many-partite entanglement are defined and discussed briefly.

  9. The Role of Information in the Economy of the Southeast.

    ERIC Educational Resources Information Center

    Curry, Elizabeth, Ed.

    1990-01-01

    This special issue presents 15 papers presented at an invitational conference on the role of information in the economic development of the southeastern region of the United States: (1) "Three Days in February: A Summary Report on the Role of Information in the Economy of the Southeast Conference" (Joel Sigmon); (2) "Impressions of…

  10. Developing Science Education Policies: How Far Is It Evidence-Based?

    ERIC Educational Resources Information Center

    Oversby, John; McGregor, Deb

    2012-01-01

    Construction of science education policy is, for most practising educators, somewhat shrouded in mist. Policies are currently conveyed by the present Secretary of State with responsibility for education through presentations of governmental papers and curricular documents. While it may seem strange that a politician can be elected one day, and…

  11. THE ROLE OF THE HEALTH DEPARTMENT IN PROVIDING DAY CARE AND HEALTH SERVICES FOR CHILDREN OF MIGRANTS.

    ERIC Educational Resources Information Center

    SCHLOESSER, PATRICIA; AND OTHERS

    PLANNING AND ORGANIZATION, HEALTH SERVICES FOR CHILDREN, AND EVALUATION OF THE PROGRAM WERE PRESENTED. THE KANSAS BOARD OF HEALTH, THE DEPARTMENT OF SOCIAL WELFARE, THE KANSAS COUNCIL OF CHURCHES, AND THE KANSAS STATE UNIVERSITY CHILD DEVELOPMENT STAFF COMBINED RESOURCES TO CARRY OUT THE PROGRAM. THE TWO STATE AGENCIES PROVIDED THE HEALTH SERVICES…

  12. Trade Is Everybody's Business [and] Teacher's Guide.

    ERIC Educational Resources Information Center

    Aaronson, Susan A.

    Trade has been an important factor in United States from the 17th century to the present day. The United States was born out of a trade dispute with Great Britain. From the moment the founders first set pen to paper, trade has helped spur U.S. economic growth. This booklet covers trade topics such as policy, perspectives, difference in nations…

  13. Low Mass X-ray Binary 4U1705-44 Exiting an Extended High X-ray State

    NASA Astrophysics Data System (ADS)

    Phillipson, Rebecca; Boyd, Patricia T.; Smale, Alan P.

    2017-09-01

    The neutron-star low-mass X-ray binary 4U1705-44, which exhibited high amplitude long-term X-ray variability on the order of hundreds of days during the 16-year continuous monitoring by the RXTE ASM (1995-2012), entered an anomalously long high state in July 2012 as observed by MAXI (2009-present).

  14. Legal Protections and Advocacy for Contingent or "Casual" Workers in the United States: A Case Study in Day Labor

    ERIC Educational Resources Information Center

    Smith, Rebecca

    2008-01-01

    Contingent, non-standard or "casual" work is present in large numbers in virtually every sector of the United States economy. Staffing strategies that use subcontracted or contingent work--strategies that once characterized only some low-wage workers such as garment and agriculture--have now spread to virtually every area of industry, including…

  15. Modeling the present and future geographic distribution of the Lone star tick, Amblyomma americanum (Ixodida: Ixodidae), in the continental United States

    USGS Publications Warehouse

    Springer, Yuri P.; Jarnevich, Catherine S.; Barnett, David T.; Monaghan, Andrew J.; Eisen, Rebecca J.

    2015-01-01

    The Lone star tick (Amblyomma americanum L.) is the primary vector for pathogens of significant public health importance in North America, yet relatively little is known about its current and potential future distribution. Building on a published summary of tick collection records, we used an ensemble modeling approach to predict the present-day and future distribution of climatically suitable habitat for establishment of the Lone star tick within the continental United States. Of the nine climatic predictor variables included in our five present-day models, average vapor pressure in July was by far the most important determinant of suitable habitat. The present-day ensemble model predicted an essentially contiguous distribution of suitable habitat extending to the Atlantic coast east of the 100th western meridian and south of the 40th northern parallel, but excluding a high elevation region associated with the Appalachian Mountains. Future ensemble predictions for 2061–2080 forecasted a stable western range limit, northward expansion of suitable habitat into the Upper Midwest and western Pennsylvania, and range contraction along portions of the Gulf coast and the lower Mississippi river valley. These findings are informative for raising awareness of A. americanum-transmitted pathogens in areas where the Lone Star tick has recently or may become established.

  16. Time-of-Day and Appendicitis: Impact on Management and Outcomes

    PubMed Central

    Drake, Frederick Thurston; Mottey, Neli E.; Castelli, Anthony A.; Florence, Michael G.; Johnson, Morris G.; Steele, Scott R.; Thirlby, Richard C.; Flum, David R.

    2017-01-01

    Background Observational research has shown that delayed presentation is associated with perforation in appendicitis. Many factors that impact the ability to present for evaluation are influenced by time-of-day; for example, child care, work, transportation, and primary care office hours. Our objective was to evaluate for an association between care processes or clinical outcomes and presentation time. Methods Prospective cohort of 7,548 adults undergoing appendectomy at 56 hospitals across Washington State. Relative to presentation time, patient characteristics, time to surgery, imaging use, negative appendectomy (NA), and perforation were compared using univariate and multivariate methodologies. Results Overall, 63% of patients presented between noon and midnight. More men presented in the morning; however, race, insurance status, co-morbid conditions, and WBC count did not differ by presentation time. Daytime presenters (6AM-6PM) were less likely to undergo imaging (94% vs. 98% p<0.05) and had a nearly 50% decrease in median pre-operative time (6.0h vs. 8.7h p<0.001). Perforation significantly differed by time-of-day. Patients who presented during the workday (9AM-3PM) had a 30% increase in odds of perforation compared to early morning/late night presenters (adjusted OR 1.29, 95%CI 1.05–1.59). NA did not vary by time-of-day. Conclusions Most patients with appendicitis presented in afternoon/evening. Socioeconomic characteristics did not vary with time-of-presentation. Patients who presented during the workday more often had perforated appendicitis compared to those who presented early morning or late night. Processes of care differed (both time-to-surgery and imaging use). Time-of-day is associated with patient outcomes, process of care, and decisions to present for evaluation; this has implications for surgical workforce planning and quality improvement efforts. PMID:27592212

  17. Errors on interrupter tasks presented during spatial and verbal working memory performance are linearly linked to large-scale functional network connectivity in high temporal resolution resting state fMRI.

    PubMed

    Magnuson, Matthew Evan; Thompson, Garth John; Schwarb, Hillary; Pan, Wen-Ju; McKinley, Andy; Schumacher, Eric H; Keilholz, Shella Dawn

    2015-12-01

    The brain is organized into networks composed of spatially separated anatomical regions exhibiting coherent functional activity over time. Two of these networks (the default mode network, DMN, and the task positive network, TPN) have been implicated in the performance of a number of cognitive tasks. To directly examine the stable relationship between network connectivity and behavioral performance, high temporal resolution functional magnetic resonance imaging (fMRI) data were collected during the resting state, and behavioral data were collected from 15 subjects on different days, exploring verbal working memory, spatial working memory, and fluid intelligence. Sustained attention performance was also evaluated in a task interleaved between resting state scans. Functional connectivity within and between the DMN and TPN was related to performance on these tasks. Decreased TPN resting state connectivity was found to significantly correlate with fewer errors on an interrupter task presented during a spatial working memory paradigm and decreased DMN/TPN anti-correlation was significantly correlated with fewer errors on an interrupter task presented during a verbal working memory paradigm. A trend for increased DMN resting state connectivity to correlate to measures of fluid intelligence was also observed. These results provide additional evidence of the relationship between resting state networks and behavioral performance, and show that such results can be observed with high temporal resolution fMRI. Because cognitive scores and functional connectivity were collected on nonconsecutive days, these results highlight the stability of functional connectivity/cognitive performance coupling.

  18. Predicting wildfire ignitions, escapes, and large fire activity using Predictive Service’s 7-Day Fire Potential Outlook in the western USA

    Treesearch

    Karin L. Riley; Crystal Stonesifer; Haiganoush Preisler; Dave Calkin

    2014-01-01

    Can fire potential forecasts assist with pre-positioning of fire suppression resources, which could result in a cost savings to the United States government? Here, we present a preliminary assessment of the 7-Day Fire Potential Outlook forecasts made by the Predictive Services program. We utilized historical fire occurrence data and archived forecasts to assess how...

  19. Long-Term Impacts of Precolonial Institutions, Geography and Ecological Diversity on Access to Public Infrastructure Services in Nigeria

    NASA Astrophysics Data System (ADS)

    Archibong, B.

    2014-12-01

    Do precolonial institutions, geography and ecological diversity affect population access to public infrastructure services over a century later? Can local leaders from historically centralized or 'conqueror' groups still influence access to public goods today? Do precolonial states located in ecologically diverse environments have better access to water, power and sanitation resources today? A growing body of literature examining the sources of the current state of African economic development has cited the enduring impacts of precolonial institutions and geography on contemporary African economic development using large sample cross-sectional analysis. In this paper, I focus on within country effects of local ethnic and political state institutions on access to public infrastructure services in present day Nigeria. Specifically, I combine information on the spatial distribution of ethnic states and ecological diversity in Nigeria circa mid 19th century and political states in Nigeria circa 1785 and 1850 with information, from a novel geocoded survey dataset, on access to public infrastructure at the local government level in present day Nigeria to examine the impact of precolonial state centralization on the current unequal access to public infrastructure services in Nigeria, accounting for the effects of ecological diversity and other geographic covariates. Some preliminary results show evidence for the long-term impacts of institutions, geography and ecological diversity on access to public infrastructure in Nigeria.

  20. Preliminary report on ground-water conditions in the Cloquet area, Carlton County, Minnesota

    USGS Publications Warehouse

    Akin, P.D.

    1951-01-01

    A study of the geology and ground-water conditions in the.area including Cloquet, Minn., was begun by the United States Geological Survey in 1948 in financial cooperation with the Minnesota State Department of Conservation, at the request of the city of Cloquet for assistance in locating large additional ground-water supplies for industrial and municipal use. The location of the area is show on figure 1. Although the present municipal wells provide a fairly adequate supply for current municipal needs, which averaged about three-quarters of a million gallons a day in 1946, there is great need for large supplies of good water, on the order of 10 million gallons a day, for use by the paper mills and other industries there. At present the industries are using water from the St. Louis River, but the water is unsatisfactory and expensive to use because it contains a large amount of objectionable organic material.

  1. A Probabilistic Assessment of the Next Geomagnetic Reversal

    NASA Astrophysics Data System (ADS)

    Buffett, Bruce; Davis, William

    2018-02-01

    Deterministic forecasts for the next geomagnetic reversal are not feasible due to large uncertainties in the present-day state of the Earth's core. A more practical approach relies on probabilistic assessments using paleomagnetic observations to characterize the amplitude of fluctuations in the geomagnetic dipole. We use paleomagnetic observations for the past 2 Myr to construct a stochastic model for the axial dipole field and apply well-established methods to evaluate the probability of the next geomagnetic reversal as a function of time. For a present-day axial dipole moment of 7.6 × 1022 A m2, the probability of the dipole entering a reversed state is less than 2% after 20 kyr. This probability rises to 11% after 50 kyr. An imminent geomagnetic reversal is not supported by paleomagnetic observations. The current rate of decline in the dipole moment is unusual but within the natural variability predicted by the stochastic model.

  2. Differences in regional blood volume during a 28-day period of abstinence in chronic cannabis smokers.

    PubMed

    Sneider, Jennifer T; Pope, Harrison G; Silveri, Marisa M; Simpson, Norah S; Gruber, Staci A; Yurgelun-Todd, Deborah A

    2008-08-01

    Cerebral blood volume (CBV) studies have provided important insight into the effects of illicit substances such as cannabis. The present study examined changes in regional blood volume in the frontal and temporal lobe, and the cerebellum during 28 days of supervised abstinence from cannabis. Dynamic susceptibility contrast MRI (DSCMRI) data were collected on 15 current, long-term cannabis users between 6 and 36 h after the subjects' last reported cannabis use (Day 0), and again after 7 and 28 days of abstinence. Resting state CBV images were also acquired on 17 healthy comparison subjects. The present findings demonstrate that at Day 7, cannabis users continued to display increased blood volumes in the right frontal region, the left and right temporal regions, and the cerebellum. However, after 28 days of abstinence, only the left temporal area and cerebellum showed significantly increased CBV values in cannabis users. These findings suggest that while CBV levels begin to normalize with continued abstinence from cannabis, specifically in frontal areas, other temporal and cerebellar brain regions show slower CBV decreases.

  3. From Turkey to Russia with Love: A Comparative Study of Higher Education Policy Strategies in Light of Ongoing Reforms

    ERIC Educational Resources Information Center

    Gazizova, Alfiya

    2012-01-01

    The article presents a comparative analysis of Turkish and Russian higher education sector development, focusing upon private-state partnership in the academic sphere, the role of universities in contemporary life, and their integration into present-day European structures. The author describes prospects, constructive ideas, and six strategies in…

  4. The Status of School Finance Today. Education Finance in the States: Its Past, Present and Future. ECS Issue Paper.

    ERIC Educational Resources Information Center

    Augenblick, John

    This paper provides a brief overview of the elementary and secondary school-finance system. The scope of the school-finance enterprise is large. On any given day, about 20 percent of the country's population participates in precollegiate education programs of some sort. The states provide nearly half of all school revenues, which come from…

  5. Failure after Farrell: Violence and Inadequate Mental Health Care in California's Division of Juvenile Justice

    ERIC Educational Resources Information Center

    Ajmani, Nisha; Webster, Erica

    2016-01-01

    From its inception in 1891 to present day, California's state youth corrections system has been mired in violence and abuse. In 1914, IQ testing and eugenics at state juvenile facilities resulted in the forced sterilization of poor, primarily non-white youth. In 1939, the suspicious suicide of a 13-year-old boy, the maltreatment of Latino youth,…

  6. Advances in threat assessment and their application to forest and rangeland management—Volume 1 and Volume 2.

    Treesearch

    John M. Pye; H. Michael Rauscher; Yasmeen Sands; Danny C. Lee; Jerome S. Beatty

    2010-01-01

    In July 2006, more than 170 researchers and managers from the United States, Canada, and Mexico convened in Boulder, Colorado, to discuss the state of the science in environmental threat assessment. This two-volume general technical report compiles peer-reviewed papers that were among those presented during the 3-day conference. Papers are organized by four broad...

  7. Paciente inmunocompetente con criptococosis cerebral: reporte de un caso.

    PubMed

    Becerra-Pedraza, Luis Cuitláhuac; Martínez-Piña, Daniel Arturo; Calles-Carmona, Génesis Rocío; San-Juan, Daniel

    2017-01-01

    A 14-year-old female, presenting sudden and progressive holocraneal headache along with incoercible vomiting arrived to emergency room. Acute confusional state and meningoencephalitis syndrome where identified. Brain computed tomography-scan with normal results was performed. Lumbar puncture with crystal-clear cerebrospinal fluid was obtained: low glucose, elevated proteins and cell-count of 15/mm. China-Ink and Criptococcus neoformans culture both positive. Viral, lupus-anticoagulant, and HIV tests negative. Fluconazole 200 mg/kg/day, amphotericin-B 0.7 mg/kg/day, dexamethasone 1 mg/kg/day were prescribed. 48-h later evolved to cerebral edema, multiple-organ-failure and death. Hereby we present a Cryptococcus spp. infection case report, addressing the public health challenge and vulnerability of immunocompromised patients in Mexico. Copyright: © 2017 SecretarÍa de Salud.

  8. Family Day Care Training Curriculum (Lao).

    ERIC Educational Resources Information Center

    Nakatsu, Gail

    California's Family Day Care Training Program was designed to recruit and train, in 7 weeks, Lao, Vietnamese, and Chinese refugees to establish their own state-licensed, family day care homes. Topics in the program's curriculum include an introduction to family day care, state licenses for family day care, state licensing requirements for family…

  9. Family Day Care Training Curriculum.

    ERIC Educational Resources Information Center

    Nakatsu, Gail

    California's Family Day Care Training Program was designed to recruit and train in 7 weeks, Lao, Vietnamese, and Chinese refugees to establish their own state-licensed, family day care homes. Topics in the program's curriculum include an introduction to family day care, state licenses for family day care, state licensing requirements for family…

  10. Pulse Shape Evolution, HER X-1

    NASA Technical Reports Server (NTRS)

    VanParadijs, Johannes A.

    1998-01-01

    This study focuses on the pulse shape evolution and spectral properties of the X-ray binary Her X-1 with regard to the well known 35-day cycle of Her X-1. A follow-up set of RXTE observations has been conducted in RXTE AO-2 phase and the two observation sets are being analyzed together. We presented results of early analysis of pulse shape evolution in "Proceedings of the Fourth Compton Symposium." More advanced analysis was presented at the HEAD meeting in November, 1997 in Estes Park, Colorado. A related study of the 35-day cycle using RXTE/ASM data, which laid out the overall picture within which the more detailed PCA observations could be placed has also been conducted. The results of this study have been published in The Astrophysical Journal, vol. 510, 974. A pair of papers on the detailed pulse evolution and the spectral/color evolution are currently being prepared for publication. Some of the significant results of this study have been a confirmation of the detailed pulse profile changes at the end of the Main High state in Her X-1 first observed by GINGA, observations of the pulse evolution in several Short High states which agree with the pulse evolution pattern predicted using a disk occultation model in the PhD Thesis of Scott 1993, observation of a systematic lengthening of the eclipse egress during the Main High state of the 35-day phase and observation of a new type of extended eclipse ingress during which pulsations cease to observed during the Short High state.

  11. 78 FR 73441 - Grants to States for Construction or Acquisition of State Homes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-06

    ... of State home facilities that furnish domiciliary, nursing home, or adult day health care to veterans... States of State home facilities that furnish domiciliary, nursing home, or adult day health care to... Providers Grant and Per Diem Program; and 64.026, Veterans State Adult Day Health Care. Signing Authority...

  12. PROFILE OF THE GULF ECOLOGY DIVISION, UNITED STATES ENVIRONMENTAL PROTECTION AGENCY

    EPA Science Inventory

    A history of the man-made island on which the Gulf Ecology Division is located,from its origin in 1876 to the present day (2007). Contains a synopsis of current research and future plans of the division.

  13. Networking in 2005: Its only Limitations May Be the Boundaries of Imagination.

    ERIC Educational Resources Information Center

    Butters, Gerry

    1998-01-01

    Presents insights into the state of networking of the near future. Discusses the promotion of virtual reality in every-day society; the unlimited bandwidth of optical networking; and terrestrial wireless links tethered to optical tools. (AEF)

  14. THE LIGHT CURVE OF HERCULES X-1 AS OBSERVED BY THE ROSSI X-RAY TIMING EXPLORER

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leahy, D. A.; Igna, Ciprian, E-mail: leahy@ucalgary.ca

    2011-07-20

    Analysis of the light curve of Hercules X-1 using the full set of archival observations of Hercules X-1 by the Rossi X-Ray Timing Explorer/Proportional Counter Array (RXTE/PCA) is reported. The observations cover time periods that Her X-1 is in main high, short high, and low states, and an anomalous low state (ALS). They include over 1.4 Ms of net exposure time. We present 35 day and orbital phase folded light curves of the count rates and softness ratios, showing the range of behaviors of Her X-1 with the high sensitivity of the RXTE/PCA. New phenomena are uncovered and previous phenomenamore » are seen in greater detail. For both main high and short high states, the fraction of time in dips is found to be a function of orbital phase and of 35 day phase. It increases steadily with orbital phase past orbital phase 0.3 and is higher at the start and end of both main high and short high states. It is higher for short high state (62%) than for main high state (28%). The normal low state data and ALS data are compared: the low state count rate is {approx}twice as high as for ALS data. The 2-4 keV to 9-20 keV softness ratio changes smoothly with orbital phase for low states and ALSs, and is indistinguishable between the two, yet very different than for the high states. This supports models for which the cause of the ALS is changed disk geometry that prevents a direct line of sight from neutron star to observer at all 35 day phases.« less

  15. Inferences About the Early Moon from Gravity and Topography

    NASA Technical Reports Server (NTRS)

    Smith, David E.; Zuber, Maria T.

    1998-01-01

    Recent spacecraft missions to the Moon have significantly improved our knowledge of the lunar gravity and topography fields and have raised some new and old questions about the early lunar history. It has frequently been assumed that the shape of the Moon today reflects an earlier equilibrium state and that the Moon has retained some internal strength. Recent analysis indicating a superisostatic state of some lunar basins lends support to this hypothesis. On its simplest level the present shape of the Moon is slightly flattened by 2.2 +/- 0.2 km while its gravity field, represented by an equipotential surface, is flattened only about 0.5 km. The hydrostatic component to the flattening arising from the Moon's present-day rotation contributes only 7 m. This difference between the topographic shape of the Moon and the shape of its gravitational equipotential has frequently been explained as the "memory" of an earlier Moon that was rotating faster and had a correspondingly larger hydrostatic flattening. To obtain this amount of hydrostatic flattening from rotation alone, and accounting for the contribution of the present-day gravity field, the Moon's rotation rate would need to be about 15 times greater than at present leading to a period of under 2 days. Maintaining its synchronous rotation with Earth would require a radius for the Moon's orbit of order 9 earth radii. Unfortunately, our confidence in the observed lunar flattening is not as great as we would like.

  16. Gangrene of the penis, scrotum, and perineum, occurred after radiotherapy of rectal cancer

    PubMed Central

    Życzkowski, Marcin; Bryniarski, Piotr; Nowakowski, Krzysztof; Muskała, Bartosz; Paradysz, Andrzej

    2013-01-01

    We present a case of a 58-year-old man hospitalized because of gangrene of the penis and scrotum, after radiochemotherapy for rectal cancer. At the time of the admission the patient presented with extensive gangrene with necrosis affecting the scrotum and the penis. During the first day of hospitalization the patient was operated. Due to the progress of the disease he had to be operated again. The status of the patient, which initially was very bad, was gradually improving. He was discharged from the hospital after 59 days in a good general state with good wound healing. PMID:24707380

  17. Papers Presented at a Conference on an EPDA Project Involving Fellowship Programs in Vocational Education (Columbus, Ohio, April 12-14, 1971).

    ERIC Educational Resources Information Center

    Bureau of Educational Personnel Development (DHEW/OE), Washington, DC.

    This publication contains papers presented during a 2-day conference attended by institutional directors of fellowship programs and state directors of vocational education. Papers are: (1) "The Overall Rationale for a Doctoral Fellowship Program" by W. Loomis, (2) "The Status of Doctoral Programs in Vocational Education" by C.…

  18. The Watershed TMP: a proposal to manage the redwood ecosystem under convergent environmental, economic and social goals

    Treesearch

    Frederick D. Euphrat

    2012-01-01

    Under present California Forest Practice Rules, mandated by the Legislature and codified by the State Board of Forestry, Non-industrial Timber Management Plans (NTMPs) give small landowners the flexibility to operate under a specific set of rules 'forever,' allowing short notice (3 days or less) for pre-approved harvest operations. This permit is presently...

  19. Number of Instructional Days/Hours in the School Year

    ERIC Educational Resources Information Center

    Rowland, Julie

    2014-01-01

    While state requirements vary on the number of instructional days and/or hours in the school year, the majority of states require 180 days of student instruction. Most also specify the minimum length of time that constitutes an instructional day. Some states set instructional time in terms of days, some specify hours, and some provide…

  20. Assessing the Energy and Emissions Implications of Alternative Population Scenarios Using a State-Level Integrated Assessment Model

    NASA Astrophysics Data System (ADS)

    Shi, W.; Nolte, C. G.; Loughlin, D. H.; Ou, Y.; Smith, S. J.

    2017-12-01

    We use GCAM-USA to examine the sensitivity of energy demands and resulting pollutant emissions and health impacts to differing population projections. The population projections are based on future fertility, mortality, migration and education assumptions consistent with the five Shared Socioeconomic Pathways (SSPs) (Jones and O'Neill, 2016). By using a state-level integrated assessment model, we capture the energy and emissions implications of population changes. Additionally, we overlay heating degree days and cooling degree days calculated from climate change projections to assess the individual and combined impacts of population shifts and climate change. A unique aspect of this work is the explicit representation of important regulatory drivers, such as the Cross-State Air Pollution Rule and vehicle efficiency standards. Preliminary results indicate there are significant differences across population scenarios in both U.S. national and state-level emissions. In this presentation, we will examine the influence of underlying factors such as climate, population, and technology changes on emissions and environmental impacts at 2050.

  1. Impairment of mitochondrial β-oxidation in rats under cold-hypoxic environment

    NASA Astrophysics Data System (ADS)

    Dutta, Arkadeb; Vats, Praveen; Singh, Vijay K.; Sharma, Yogendra K.; Singh, Som N.; Singh, Shashi B.

    2009-09-01

    Mitochondrial ß-oxidation of fatty acid provides a major source of energy in mammals. High altitude (HA), characterized by hypobaric hypoxia and low ambient temperatures, causes alteration in metabolic homeostasis. Several studies have depicted that hypoxic exposure in small mammals causes hypothermia due to hypometabolic state. Moreover, cold exposure along with hypoxia reduces hypoxia tolerance in animals. The present study investigated the rate of β-oxidation and key enzymes, carnitine palmitoyl transferase-I (CPT-I) and hydroxyacyl CoA dehydrogenase (HAD), in rats exposed to cold-hypobaric hypoxic environment. Male Sprague Dawley rats (190-220 g) were randomly divided into eight groups ( n = 6 rats in each group): 1 day hypoxia (H1); 7 days hypoxia (H7); 1 day cold (C1); 7 days cold (C7); 1 day cold-hypoxia (CH1); 7 days cold-hypoxia (CH7) exposed; and unexposed control for 1 and 7 days (UC1 and UC7). After exposure, animals were anaesthetized with ketamine (50 mg/kg body weight) and xylazine (10 mg/kg body weight) intraperitonialy and sacrificed. Mitochondrial CPT-I, HAD, 14C-palmitate oxidation in gastrocnemius muscle and liver, and plasma leptin were measured. Mitochondrial CPT-I was significantly reduced in muscle and liver in CH1 and CH7 as compared to respective controls. HAD activity was significantly reduced in H1 and CH7, and in H1, H7, CH1, and CH7 as compared to unexposed controls in muscle and liver, respectively. A concomitant decrease in 14C-palmitate oxidation was found. Significant reduction in plasma leptin in hypoxia and cold-hypoxia suggested hypometabolic state. It can be concluded that ß-oxidation of fatty acids is reduced in rats exposed to cold-hypoxic environment due to the persisting hypometabolic state in cold-hypoxia exposure.

  2. Basic diagnosis of solid waste generated at Agua Blanca State Park to propose waste management strategies.

    PubMed

    Laines Canepa, José Ramón; Zequeira Larios, Carolina; Valadez Treviño, Maria Elena Macías; Garduza Sánchez, Diana Ivett

    2012-03-01

    State parks are highly sensitive areas of great natural importance and tourism value. Herein a case study involving a basic survey of solid waste which was carried out in 2006 in Agua Blanca State Park, Macuspana, Tabasco, Mexico with two sampling periods representing the high and low tourist season is presented. The survey had five objectives: to find out the number of visitors in the different seasons, to consider the daily generation of solid waste from tourist activities, to determine bulk density, to select and quantify sub-products; and to suggest a possible treatment. A daily average of 368 people visited the park: 18,862 people in 14 days during the high season holiday (in just one day, Easter Sunday, up to 4425 visitors) and 2092 visitors in 43 days during the low season. The average weight of the generated solid waste was 61.267 kg day(-1) and the generated solid waste average per person was 0.155 kg person(-1 ) day(-1). During the high season, the average increased to 0.188 kg person(-1 ) day(-1) and during the low season, the average decreased to 0.144 kg person(-1 ) day(-1). The bulk density average was 75.014 kg m(-3), the maximum value was 92.472 kg m(-3) and the minimum was 68.274 kg m(-3). The sub-products comprised 54.52% inorganic matter; 32.03% organic matter, 10.60% non-recyclable and 2.85% others. Based on these results, waste management strategies such as reuse/recycling, aerobic and anaerobic digestion, the construction of a manual landfill and the employment of a specialist firm were suggested.

  3. Human rabies prevention--United States, 2008: recommendations of the Advisory Committee on Immunization Practices.

    PubMed

    Manning, Susan E; Rupprecht, Charles E; Fishbein, Daniel; Hanlon, Cathleen A; Lumlertdacha, Boonlert; Guerra, Marta; Meltzer, Martin I; Dhankhar, Praveen; Vaidya, Sagar A; Jenkins, Suzanne R; Sun, Benjamin; Hull, Harry F

    2008-05-23

    These recommendations of the Advisory Committee on Immunization Practices (ACIP) update the previous recommendations on human rabies prevention (CDC. Human rabies prevention--United States, 1999: recommendations of the Advisory Committee on Immunization Practices. MMWR 1999;48 [No. RR-1]) and reflect the status of rabies and antirabies biologics in the United States. This statement 1) provides updated information on human and animal rabies epidemiology; 2) summarizes the evidence regarding the effectiveness/efficacy, immunogenicity, and safety of rabies biologics; 3) presents new information on the cost-effectiveness of rabies postexposure prophylaxis; 4) presents recommendations for rabies postexposure and pre-exposure prophylaxis; and 5) presents information regarding treatment considerations for human rabies patients. These recommendations involve no substantial changes to the recommended approach for rabies postexposure or pre-exposure prophylaxis. ACIP recommends that prophylaxis for the prevention of rabies in humans exposed to rabies virus should include prompt and thorough wound cleansing followed by passive rabies immunization with human rabies immune globulin (HRIG) and vaccination with a cell culture rabies vaccine. For persons who have never been vaccinated against rabies, postexposure antirabies vaccination should always include administration of both passive antibody (HRIG) and vaccine (human diploid cell vaccine [HDCV] or purified chick embryo cell vaccine [PCECV]). Persons who have ever previously received complete vaccination regimens (pre-exposure or postexposure) with a cell culture vaccine or persons who have been vaccinated with other types of vaccines and have previously had a documented rabies virus neutralizing antibody titer should receive only 2 doses of vaccine: one on day 0 (as soon as the exposure is recognized and administration of vaccine can be arranged) and the second on day 3. HRIG is administered only once (i.e., at the beginning of antirabies prophylaxis) to previously unvaccinated persons to provide immediate, passive, rabies virus neutralizing antibody coverage until the patient responds to HDCV or PCECV by actively producing antibodies. A regimen of 5 1-mL doses of HDCV or PCECV should be administered intramuscularly to previously unvaccinated persons. The first dose of the 5-dose course should be administered as soon as possible after exposure (day 0). Additional doses should then be administered on days 3, 7, 14, and 28 after the first vaccination. Rabies pre-exposure vaccination should include three 1.0-mL injections of HDCV or PCECV administered intramuscularly (one injection per day on days 0, 7, and 21 or 28). Modifications were made to the language of the guidelines to clarify the recommendations and better specify the situations in which rabies post- and pre-exposure prophylaxis should be administered. No new rabies biologics are presented, and no changes were made to the vaccination schedules. However, rabies vaccine adsorbed (RVA, Bioport Corporation) is no longer available for rabies postexposure or pre-exposure prophylaxis, and intradermal pre-exposure prophylaxis is no longer recommended because it is not available in the United States.

  4. The Myths of India.

    ERIC Educational Resources Information Center

    Day, Frederick A.

    1988-01-01

    Stating that superficial stereotypes hinder the understanding of people and places, Day presents several well-known over-generalizations about India. Attempts to update readers about recent changes within the country while dispelling some popular myths. Discusses India's large population, poverty, economic growth, women's roles, and culture, along…

  5. President Nixon and Apollo 13 crewmen at Hickam AFB

    NASA Image and Video Library

    1970-04-18

    S70-15526 (18 April 1970) --- President Richard M. Nixon and the Apollo 13 crew members pay honor to the United States flag during the post-mission ceremonies at Hickam Air Force Base, Hawaii. Astronauts James A. Lovell Jr., (United States Navy Captain, salutes the flag) commander; John L. Swigert Jr., command module pilot (right); and Fred W. Haise Jr., lunar module pilot (left), were presented the Presidential Medal of Freedom by the Chief Executive. The Apollo 13 splashdown occurred at 12:07:44 p.m. (CST), April 17, 1970, about a day and a half prior to the award presentation.

  6. Shame as a predictor of post-event rumination in social anxiety.

    PubMed

    Cândea, Diana-Mirela; Szentágotai-Tătar, Aurora

    2017-12-01

    Evidence shows that people with high social anxiety levels ruminate about distressing social events, which contributes to the maintenance of social anxiety symptoms. The present study aimed to explore the role of shame in maintaining post-event rumination (PER) following a negative social event (an impromptu speech with negative feedback) in a student sample (N = 104). Participants reported negative rumination related to the event one day and one week after the speech. PER measured one day after the speech was not associated with social anxiety symptoms and state anxiety. One week later, participants with clinically relevant social anxiety symptoms experienced greater PER. State shame was the only significant predictor of PER in a regression equation that also included social anxiety symptoms, state anxiety and self-evaluation of performance. Possible explanations and implications are discussed in light of cognitive models of social anxiety.

  7. Characterization of increased persistence and intensity of precipitation in the northeastern United States

    NASA Astrophysics Data System (ADS)

    Guilbert, Justin; Betts, Alan K.; Rizzo, Donna M.; Beckage, Brian; Bomblies, Arne

    2015-03-01

    We present evidence of increasing persistence in daily precipitation in the northeastern United States that suggests that global circulation changes are affecting regional precipitation patterns. Meteorological data from 222 stations in 10 northeastern states are analyzed using Markov chain parameter estimates to demonstrate that a significant mode of precipitation variability is the persistence of precipitation events. We find that the largest region-wide trend in wet persistence (i.e., the probability of precipitation in 1 day and given precipitation in the preceding day) occurs in June (+0.9% probability per decade over all stations). We also find that the study region is experiencing an increase in the magnitude of high-intensity precipitation events. The largest increases in the 95th percentile of daily precipitation occurred in April with a trend of +0.7 mm/d/decade. We discuss the implications of the observed precipitation signals for watershed hydrology and flood risk.

  8. Effects of ionospheric modification on system performance

    NASA Astrophysics Data System (ADS)

    Ganguly, Suman

    1989-12-01

    Controlled ionospheric modification can be used for disrupting as well as facilitating communication and radar systems. After briefly describing the results achieved with the present day ionospheric modification facilities, a scenario is presented for the generation of strong and significant ionospheric modification. A few schemes are presented for the development of modern high power facilities using the state of the art technology and then the impact of such facilities on the system performance is described.

  9. “As Good As It Gets”1: Undocumented Latino Day Laborers Negotiating Discrimination in San Francisco and Berkeley, California, USA

    PubMed Central

    Quesada, James; Arreola, Sonya; Kral, Alex; Khoury, Sahar; Organista, Kurt C.; Worby, Paula

    2014-01-01

    Undocumented Latino day laborers in the United States are vulnerable to being arrested and expelled at any time. This social fact shapes their everyday lives in terms of actions taken and strategies deployed to mitigate being confronted, profiled, and possibly incarcerated and deported. While perceptions of threat and bouts of discrimination are routine among undocumented Latino day laborers, their specific nature vary according to multiple social factors and structural forces that differ significantly from locale to locale. The experience of discrimination is often tacitly negotiated through perceptions, decisions, and actions toward avoiding or moderating its ill effects. This essay examines urban undocumented Latino day laborers over a variety of sites in the greater San Francisco Bay Area, which, compared to many metropolitan areas in the U.S. is “as good as it gets” in terms of being socially tolerated and relatively safe from persecution. Nonetheless, tacit negotiations are necessary to withstand or overcome challenges presented by idiosyncratic and ever changing global, national/state, and local dynamics of discrimination. [undocumented Latino laborers, social exclusion, discrimination, tacit negotiation] PMID:24910501

  10. Did LMC X-3 Undergo a 'Her X-1-like' Anomalous Low State?

    NASA Technical Reports Server (NTRS)

    Boyd, Patricia t.

    2008-01-01

    The black hole X-ray binary LMC X-3 has been monitored by the Rossi X-ray Timing Explorer (RXTE) from its launch to the present by the All-Sky Monitor (ASM). This well-sampled light curve is supplemented by frequent pointed observations with the PCA and HEXTE instruments which provide improved sensitivity, time resolution and spectral information. The long-term X-ray luminosity of the system is strongly modulated on timescales of hundreds of days. The mean 2-10 kev X-ray flux varies by a factor of more than 100 during this long-term cycle. This variability has been attributed to the precession of a bright, tilted, and warped accretion disk---the mechanism also invoked to explain the 35-day super-orbital period in the X-ray binary pulsar system Her X-1. The ASM light curve displays a unique episode, starting in December 2003, during which LMC X-3 displayed a very low, nearly constant flux, for about 80 days. This is markedly different from the typical low-flux excursions in LMC X-3, which smoothly evolve toward and then away from a minimum flux on about a 10-day time scale. The character of the long-term variability, as measured by amplitude and characteristic time scale, is not the same after this long low state as it was before. Similar shifts in long-term period and amplitude are seen after the so-called "anomalous low states" in Her X-1, when the 35-day X-ray modulation ceases for an unpredictable length of time. These similar shifts in the long-term amplitude and timescale in the two systems suggests they share a similar mechanism which gives rise to the anomalous low states

  11. Summary of Selected State Licensing Requirements: Day Care Centers, Family Day Care Homes. Day Care Survey--1970. Preliminary Edition.

    ERIC Educational Resources Information Center

    Office of Economic Opportunity, Washington, DC. Evaluation Div.

    This volume of abstracts of child day care facility licensing requirements is intended to serve as an introduction to selected aspects of the licensing process within the several states by reviewing (1) the various definitions of day care facilities in the jurisdictions covered, and (2) the prescribed regulations established by the states to…

  12. Catching Up on State Transitions in Cygnus X-1

    NASA Technical Reports Server (NTRS)

    Boeck, Moritz; Hanke, Manfred; Wilms, Joern; Pirner, Stefan; Grinberg, Victoria; Markoff, Sera; Pottschmidt, Katja; Nowak, Michael A.; Pooley, Guy

    2008-01-01

    In 2005 February we observed Cygnus X-1 over a period of 10 days quasi-continuously with the Rossi X-ray Timing Explorer and the Ryle telescope. We present the results of the spectral and timing analysis on a timescale of 90 min and show that the behavior of Cyg X-1 is similar to that found during our years long monitoring campaign. As a highlight we present evidence for a full transition from the hard to the soft state that happened during less than three hours. The observation provided a more complete picture of a state transition than before, especially concerning the evolution of the time lags, due to unique transition coverage and analysis with high time resolution.

  13. In the Shadow of the Cold War: The Caribbean and Central America in U.S. Foreign Policy. [and] Teacher's Resource Book. Revised. Choices for the 21st Century.

    ERIC Educational Resources Information Center

    Brown Univ., Providence, RI. Thomas J. Watson, Jr. Inst. for International Studies.

    This unit examines the economic and military concerns that have linked the Caribbean and Central America to the United States. The first section of the first booklet reviews the history of U.S. involvement in the region from the mid-1800s to the early 1960s. Part 2 focuses on the Cuban missile crisis of 1962 and presents a day-by-day account of…

  14. Protecting Children in Day Care: Building a National Background Check System. Hearing before the Committee on the Judiciary, United States Senate, One Hundred Second Congress, First Session on the National Child Protection Act of 1991.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on the Judiciary.

    In his opening statement at this hearing, committee chairman Senator Joseph Biden mentioned the National Child Protection Act of 1991; praised Oprah Winfrey's efforts to support programs and legislation to prevent sexual abuse of children; presented data on the incidence of sexual abuse of children in the home and in day care centers; and…

  15. Speaking With Us.

    ERIC Educational Resources Information Center

    Yakima Valley Coll., WA.

    An illustrated workbook containing exercises in speaking and writing skills designed for a beginning learner of English as a second language is presented. The workbook includes material on greetings, giving personal information, numbers, time, days of the week, holidays, body parts, health information, states of being, food, colors, clothing,…

  16. 19 CFR 207.24 - Hearing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... EXPORTS TO THE UNITED STATES Final Determinations, Short Life Cycle Products § 207.24 Hearing. (a) In... closed, presentations at the hearing shall not include business proprietary information. Notwithstanding... the Secretary no later than three (3) business days before the hearing. In the case of testimony to be...

  17. A historical review of managed honey bee populations in Europe and the United States and the factors that may affect them.

    PubMed

    Vanengelsdorp, Dennis; Meixner, Marina Doris

    2010-01-01

    Honey bees are a highly valued resource around the world. They are prized for their honey and wax production and depended upon for pollination of many important crops. While globally honey bee populations have been increasing, the rate of increase is not keeping pace with demand. Further, honey bee populations have not been increasing in all parts of the world, and have declined in many nations in Europe and in North America. Managed honey bee populations are influenced by many factors including diseases, parasites, pesticides, the environment, and socio-economic factors. These factors can act alone or in combination with each other. This review highlights the present day value of honey bees, followed by a detailed description of some of the historical and present day factors that influence honey bee populations, with particular emphasis on colony populations in Europe and the United States. Copyright 2009 Elsevier Inc. All rights reserved.

  18. From Scientific Management to Social Justice...and Back Again? Pedagogical Shifts in the Study and Practice of Educational Leadership

    ERIC Educational Resources Information Center

    Brooks, Jeffrey S.; Miles, Mark

    2006-01-01

    This article presents an historical overview of pedagogical orientations of school leadership in the United States, and then considers issues facing contemporary educational leaders in this context. Our survey begins with a consideration of the early influence of Frederick Taylor and ends in the present day, a time when the fields of practice and…

  19. 78 FR 62337 - Columbus Day, 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-18

    ... Columbus Day, 2013 By the President of the United States of America A Proclamation Late in the summer of... year as ``Columbus Day.'' NOW, THEREFORE, I, BARACK OBAMA, President of the United States of America, do hereby proclaim October 14, 2013, as Columbus Day. I call upon the people of the United States to...

  20. A conceptual model of oceanic heat transport in the Snowball Earth scenario

    NASA Astrophysics Data System (ADS)

    Comeau, Darin; Kurtze, Douglas A.; Restrepo, Juan M.

    2016-12-01

    Geologic evidence suggests that the Earth may have been completely covered in ice in the distant past, a state known as Snowball Earth. This is still the subject of controversy, and has been the focus of modeling work from low-dimensional models up to state-of-the-art general circulation models. In our present global climate, the ocean plays a large role in redistributing heat from the equatorial regions to high latitudes, and as an important part of the global heat budget, its role in the initiation a Snowball Earth, and the subsequent climate, is of great interest. To better understand the role of oceanic heat transport in the initiation of Snowball Earth, and the resulting global ice covered climate state, the goal of this inquiry is twofold: we wish to propose the least complex model that can capture the Snowball Earth scenario as well as the present-day climate with partial ice cover, and we want to determine the relative importance of oceanic heat transport. To do this, we develop a simple model, incorporating thermohaline dynamics from traditional box ocean models, a radiative balance from energy balance models, and the more contemporary "sea glacier" model to account for viscous flow effects of extremely thick sea ice. The resulting model, consisting of dynamic ocean and ice components, is able to reproduce both Snowball Earth and present-day conditions through reasonable changes in forcing parameters. We find that including or neglecting oceanic heat transport may lead to vastly different global climate states, and also that the parameterization of under-ice heat transfer in the ice-ocean coupling plays a key role in the resulting global climate state, demonstrating the regulatory effect of dynamic ocean heat transport.

  1. Work related injuries in Washington State's Trucking Industry, by industry sector and occupation.

    PubMed

    Smith, Caroline K; Williams, Jena

    2014-04-01

    The trucking industry continues to have some of the highest work-related injury and illness rates and costs of any industry in the United States. Until recently, little focus has been placed on addressing non-motor vehicle collision related injuries within the trucking industry. Drivers are exposed to multiple physical risk factors that contribute to occupational injuries in order to complete their job duties, such as loading/unloading freight, decoupling trailers, strapping down loads and ingress and egress from the cab and trailer. About one-fourth of all truck driver injuries in the United States are related to slips, trips, and falls near the truck. The purpose of this descriptive study is to report on recent injuries in the trucking industry in Washington State. Data are presented by occupation and industry sector, in order to better understand the magnitude of specific injuries in terms of time-loss days and workers' compensation costs. All accepted, compensable (time-loss) claims from 2005 to 2010 within the trucking industry in Washington State were reviewed. Counts, rates, median and quartile data are presented. Logistic regression models are presented to identify factors associated with more severe claims. Non-traumatic musculoskeletal disorders of the neck, back and upper extremities are the most frequent injuries across all industry sectors and occupations in the trucking industry. Vehicle related claims had the highest median costs and time loss days and Courier and Messenger claims had the highest risk for higher time loss claims. Injuries varied substantially by sector and within sectors by occupation. It is important to review work-related injuries within the trucking industry by sector and occupation in order to maximize limited resources for injury prevention within this important sector. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  2. Sad man's nose: Emotion induction and olfactory perception.

    PubMed

    Flohr, Elena L R; Erwin, Elena; Croy, Ilona; Hummel, Thomas

    2017-03-01

    Emotional and olfactory processing is frequently shown to be closely linked both anatomically and functionally. Depression, a disease closely related to the emotional state of sadness, has been shown to be associated with a decrease in olfactory sensitivity. The present study focuses on the state of sadness in n = 31 healthy subjects in order to investigate the specific contribution of this affective state in the modulation of olfactory processing. A sad or indifferent affective state was induced using 2 movies that were presented on 2 separate days. Afterward, chemosensory-evoked potentials were recorded after stimulation with an unpleasant (hydrogen sulfide: "rotten eggs") or a pleasant (phenyl ethyl alcohol: "rose") odorant. Latencies of N1 and P2 peaks were longer after induction of the sad affective state. Additionally, amplitudes were lower in a sad affective state when being stimulated with the unpleasant odorant. Processing of olfactory input has thus been reduced under conditions of the sad affective state. We argue that the affective state per se could at least partially account for the reduced olfactory sensitivity in depressed patients. To our knowledge, the present study is the first to show influence of affective state on chemosensory event-related potentials. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  3. Two drastically different climate states on an Earth-like terra-planet

    NASA Astrophysics Data System (ADS)

    Kalidindi, Sirisha; Reick, Christian H.; Raddatz, Thomas; Claussen, Martin

    2018-06-01

    We study an Earth-like terra-planet (water-limited terrestrial planet) with an overland recycling mechanism bringing fresh water back from the high latitudes to the low latitudes. By performing model simulations for such a planet we find two drastically different climate states for the same set of boundary conditions and parameter values: a cold and wet (CW) state with dominant low-latitude precipitation and a hot and dry (HD) state with only high-latitude precipitation. We notice that for perpetual equinox conditions, both climate states are stable below a certain threshold value of background soil albedo while above the threshold only the CW state is stable. Starting from the HD state and increasing background soil albedo above the threshold causes an abrupt shift from the HD state to the CW state resulting in a sudden cooling of about 35 °C globally, which is of the order of the temperature difference between present day and the Snowball Earth state. When albedo starting from the CW state is reduced down to zero the terra-planet does not shift back to the HD state (no closed hysteresis). This is due to the high cloud cover in the CW state hiding the surface from solar irradiation so that surface albedo has only a minor effect on the top of the atmosphere radiation balance. Additional simulations with present-day Earth's obliquity all lead to the CW state, suggesting a similar abrupt transition from the HD state to the CW state when increasing obliquity from zero. Our study also has implications for the habitability of Earth-like terra-planets. At the inner edge of the habitable zone, the higher cloud cover in the CW state cools the planet and may prevent the onset of a runaway greenhouse state. At the outer edge, the resupply of water at low latitudes stabilizes the greenhouse effect and keeps the planet in the HD state and may prevent water from getting trapped at high latitudes in frozen form. Overall, the existence of bistability in the presence of an overland recycling mechanism hints at the possibility of a wider habitable zone for Earth-like terra-planets at low obliquities.

  4. 78 FR 37429 - Father's Day, 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... Day, 2013 By the President of the United States of America A Proclamation Each day, men from every... father's love, day after day. NOW, THEREFORE, I, BARACK OBAMA, President of the United States of America.... 109), do hereby proclaim June 16, 2013, as Father's Day. I direct the appropriate officials of the...

  5. Evidence for a 17-d periodicity from Cyg X-3

    NASA Technical Reports Server (NTRS)

    Holt, S. S.; Boldt, E. A.; Serlemitsos, P. J.; Kaluzienski, L. J.; Pravdo, S. H.; Peacock, A.; Elvis, M.; Watson, M. G.; Pounds, K. A.

    1976-01-01

    Data are presented from the Ariel-V All-Sky Monitor which indicate a 17-day periodicity of the X-ray spectra from Cyg X-3 (3U2030+40). The data are consistent with data from the Ariel V Sky Survey Experiment. Assuming that the high intensity state of Cyg X-3 is well fitted by a structureless black body (Serlemitsos et al., 1975), and that the 17-day maxima correspond to increased electron scattering in the source, it is suggested that the 17-day effect is analogous to the 35-day variation in Her X-1. The possible explanation of this phenomenon as a result of the 17-day orbital period of the binary system containing Cyg X-3 is severely constrained by the stability of the well-known 4.8-hour variation.

  6. Coherent generation of photonic fractional quantum Hall states in a cavity and the search for anyonic quasiparticles

    NASA Astrophysics Data System (ADS)

    Dutta, Shovan; Mueller, Erich J.

    2018-03-01

    We present and analyze a protocol in which polaritons in a noncoplanar optical cavity form fractional quantum Hall states. We model the formation of these states and present techniques for subsequently creating anyons and measuring their fractional exchange statistics. In this protocol, we use a rapid adiabatic passage scheme to sequentially add polaritons to the system, such that the system is coherently driven from n - to (n +1 )-particle Laughlin states. Quasiholes are created by slowly moving local pinning potentials in from outside the cloud. They are braided by dragging the pinning centers around one another, and the resulting phases are measured interferometrically. The most technically challenging issue with implementing our procedure is that maintaining adiabaticity and coherence requires that the two-particle interaction energy V0 be sufficiently large compared to the single-polariton decay rate γ , V0/γ ≫10 N2lnN , where N is the number of particles in the target state. While this condition is very demanding for present-day experiments where V0/γ ˜50 , our protocol presents a significant advance over the existing protocols in the literature.

  7. Regional Forum on Distance Learning. A Report.

    ERIC Educational Resources Information Center

    O'Connor, Bridget; Levinson, Cynthia, Ed.

    The audio teleconference summarized in this report joined six state education agencies (Arkansas, Louisiana, Mississippi, New Mexico, Oklahoma, and Texas) and the National Institute of Education with experts nationally and abroad for 3 days in April 1984. Presentations summarized include (1) "The Need to Consider Alternative Delivery,"…

  8. Smoking and the First Amendment: A Unit of Study.

    ERIC Educational Resources Information Center

    Fernekes, William R.

    1988-01-01

    Provides a model reflective inquiry strategy to educate students about the controversy surrounding the proposed ban on tobacco advertising. Presents a 15-day lesson sequence which explores implications for clashes between individual rights and state power, and includes a list of resources for classroom use. (LS)

  9. From Awareness to Action.

    ERIC Educational Resources Information Center

    Ruckelshaus, William D.

    An address evaluating the environmental situation, presented by William D. Ruckelshaus, Administrator of the Environmental Protection Agency, is contained in this document. Delivered for an Earth Day program at Ohio State University, Columbus, Ohio, April 22, 1971, it stresses the point that environmental concern has changed from an era of…

  10. Listeria monocytogenes septicemia in an immunocompromised dog

    USDA-ARS?s Scientific Manuscript database

    An 11-year-old, male castrated, Boston Terrier was presented to the North Carolina State University College of Veterinary Medicine Small Animal Emergency Service with a 2-day history of progressive ataxia, left-sided head tilt, and anorexia. The dog had previously been diagnosed with chronic lymphoi...

  11. Early Mathematics Fluency with CCSSM

    ERIC Educational Resources Information Center

    Matney, Gabriel T.

    2014-01-01

    To develop second-grade students' confidence and ease, this author presents examples of learning tasks (Number of the Day, Word Problem Solving, and Modeling New Mathematical Ideas) that align with Common Core State Standards for Mathematics and that build mathematical fluency to promote students' creative expression of mathematical…

  12. NASA's Current and Next Generation Coastal Remote Sensing Missions and Coral Reef Projects.

    NASA Technical Reports Server (NTRS)

    Guild, Liane S.

    2015-01-01

    The LLILAS Faculty Research Initiative presents a two-day symposium, Caribbean Coral Reefs at Risk. This international symposium examines the current state and future of coral reef conservation efforts throughout the Caribbean from the perspective of government agencies, nongovernment organizations, and academia.

  13. 38 CFR 52.20 - Application for recognition based on certification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... VETERANS AFFAIRS (CONTINUED) PER DIEM FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Obtaining Per Diem for Adult Day Health Care in State Homes § 52.20 Application for recognition based on certification. To apply for recognition and certification of a State home for adult day health care, a State...

  14. 38 CFR 52.20 - Application for recognition based on certification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... VETERANS AFFAIRS (CONTINUED) PER DIEM FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Obtaining Per Diem for Adult Day Health Care in State Homes § 52.20 Application for recognition based on certification. To apply for recognition and certification of a State home for adult day health care, a State...

  15. 38 CFR 52.20 - Application for recognition based on certification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... VETERANS AFFAIRS (CONTINUED) PER DIEM FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Obtaining Per Diem for Adult Day Health Care in State Homes § 52.20 Application for recognition based on certification. To apply for recognition and certification of a State home for adult day health care, a State...

  16. NCI Think Tank Concerning the Identifiability of Biospecimens and “-Omic” Data

    PubMed Central

    Weil, Carol J.; Mechanic, Leah E.; Green, Tiffany; Kinsinger, Christopher; Lockhart, Nicole C.; Nelson, Stefanie A.; Rodriguez, Laura L.; Buccini, Laura D.

    2014-01-01

    On June 11 and 12, 2012, the National Cancer Institute (NCI) hosted a think tank concerning the identifiability of biospecimens and “omic” Data in order to explore challenges surrounding this complex and multifaceted topic. The think tank brought together forty-six leaders from several fields, including cancer genomics, bioinformatics, human subject protection, patient advocacy, and commercial genetics. The first day involved presentations regarding the state of the science of re-identification; current and proposed regulatory frameworks for assessing identifiability; developments in law, industry and biotechnology; and the expectations of patients and research participants. The second day was spent by think tank participants in small break-out groups designed to address specific sub-topics under the umbrella issue of identifiability, including considerations for the development of best practices for data sharing and consent, and targeted opportunities for further empirical research. We describe the outcomes of this two day meeting, including two complimentary themes that emerged from moderated discussions following the presentations on Day 1, and ideas presented for further empirical research to discern the preferences and concerns of research participants about data sharing and individual identifiability. PMID:23579437

  17. Experimental evidence that bioenergetics disruption is not mainly involved in the brain injury of glutaryl-CoA dehydrogenase deficient mice submitted to lysine overload.

    PubMed

    Amaral, Alexandre Umpierrez; Cecatto, Cristiane; Seminotti, Bianca; Ribeiro, César Augusto; Lagranha, Valeska Lizzi; Pereira, Carolina Coffi; de Oliveira, Francine Hehn; de Souza, Diogo Gomes; Goodman, Stephen; Woontner, Michael; Wajner, Moacir

    2015-09-16

    Bioenergetics dysfunction has been postulated as an important pathomechanism of brain damage in glutaric aciduria type I, but this is still under debate. We investigated activities of citric acid cycle (CAC) enzymes, lactate release, respiration and membrane potential (ΔΨm) in mitochondrial preparations from cerebral cortex and striatum of 30-day-old glutaryl-CoA dehydrogenase deficient (Gcdh-/-) and wild type mice fed a baseline or a high lysine (Lys, 4.7%) chow for 60 or 96h. Brain histological analyses were performed in these animals, as well as in 90-day-old animals fed a baseline or a high Lys chow during 30 days starting at 60-day-old. A moderate reduction of citrate synthase and isocitrate dehydrogenase activities was observed only in the striatum from 30-day-old Gcdh-/- animals submitted to a high Lys chow. In contrast, the other CAC enzyme activities, lactate release, the respiratory parameters state 3, state 4, the respiratory control ratio and CCCP-stimulated (uncoupled) state, as well as ΔΨm were not altered in the striatum. Similarly, none of the evaluated parameters were changed in the cerebral cortex from these animals under baseline or Lys overload. On the other hand, histological analyses revealed the presence of intense vacuolation in the cerebral cortex of 60 and 90-day-old Gcdh-/- mice fed a baseline chow and in the striatum of 90-day-old Gcdh-/- mice submitted to Lys overload for 30 days. Taken together, the present data demonstrate mild impairment of bioenergetics homeostasis and marked histological alterations in striatum from Gcdh-/- mice under a high Lys chow, suggesting that disruption of energy metabolism is not mainly involved in the brain injury of these animals. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. 77 FR 59648 - Notice of Inventory Completion: San Francisco State University, NAGPRA Program, San Francisco, CA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ...The San Francisco State University NAGPRA Program has completed an inventory of human remains and associated funerary objects, in consultation with the appropriate Indian tribe, and has determined that there is a cultural affiliation between the human remains and associated funerary objects and a present-day Indian tribe. Representatives of any Indian tribe that believes itself to be culturally affiliated with the human remains and associated funerary objects may contact the San Francisco State University NAGPRA Program. Repatriation of the human remains and associated funerary objects to the Indian tribe stated below may occur if no additional claimants come forward.

  19. Age-period-cohort modelling of alcohol volume and heavy drinking days in the US National Alcohol Surveys: divergence in younger and older adult trends.

    PubMed

    Kerr, William C; Greenfield, Thomas K; Bond, Jason; Ye, Yu; Rehm, Jürgen

    2009-01-01

    The decomposition of trends in alcohol volume and heavy drinking days into age, period, cohort and demographic effects offers an important perspective on the dynamics of change in alcohol use patterns in the United States. The present study utilizes data from six National Alcohol Surveys conducted over the 26-year period between 1979 and 2005. Setting United States. Alcohol volume and the number of days when five or more and eight or more drinks were consumed were derived from overall and beverage-specific graduated frequency questions. Trend analyses show that while mean values of drinking measures have continued to decline for those aged 26 and older, there has been a substantial increase in both alcohol volume and 5+ days among those aged 18-25 years. Age-period-cohort models indicate a potential positive cohort effect among those born after 1975. However, an alternative interpretation of an age-cohort interaction where drinking falls off more steeply in the late 20s than was the case in the oldest surveys cannot be ruled out. For women only, the 1956-60 birth cohort appears to drink more heavily than those born just before or after. Models also indicate the importance of income, ethnicity, education and marital status in determining these alcohol measures. Increased heavy drinking among young adults in recent surveys presents a significant challenge for alcohol policy and may indicate a sustained increase in future US alcohol consumption.

  20. Lopimune-induced mitochondrial toxicity is attenuated by increased uncoupling protein-2 level in treated mouse hepatocytes.

    PubMed

    El Hoss, Sara; Bahr, Georges M; Echtay, Karim S

    2015-06-15

    Although the protease inhibitor (PI) Lopimune has proven to be effective, no studies have examined the side effects of Lopimune on mitochondrial bioenergetics in hepatocytes. The objective of the present study is to evaluate mitochondrial respiration, production of reactive oxygen species (ROS) and expression of uncoupling protein-2 (UCP2) in mouse hepatocytes following Lopimune administration. Mitochondria were extracted from mouse liver using differential centrifugation and hepatocytes were isolated by the collagenase perfusion procedure. Mitochondrial respiration was measured using a Rank Brothers oxygen electrode. ROS production in hepatocytes was monitored by flow cytometry using a 2',7'-dichlorofluorescin diacetate probe and UCP2 protein expression was detected by Western blotting. We found that Lopimune induced a significant decrease of approximately 30% in the respiratory control ratio (RCR) starting from day 4 until day 9 of treatment. This decrease was due to an increase in state 4 respiration, reflecting an increase in mitochondrial proton leak. State 2 and state 3 respirations were not affected. Moreover, ROS production significantly increased by about 2-fold after day 1 of treatment and decreased after day 3, returning to the resting level on day 5. Interestingly, UCP2 which is absent from control hepatocytes, was expressed starting from day 4 of treatment. Our findings indicate that Lopimune-induced proton leak, mediated by UCP2, may represent a response to inhibit the production of ROS as a negative feedback regulatory mechanism. These results imply a potential involvement of UCP2 in the regulation of oxidative stress and add new insights into the understanding of mitochondrial toxicity induced by PIs. © The Authors Journal compilation © 2015 Biochemical Society.

  1. Global Warming Impacts on Heating and Cooling Degree-Days in the United States

    NASA Astrophysics Data System (ADS)

    Petri, Y.; Caldeira, K.

    2014-12-01

    Anthropogenic climate change is expected to significantly alter residential air conditioning and space heating requirements, which account for 41% of U.S. household energy expenditures. The degree-day method can be used for reliable estimation of weather related building energy consumption and costs, as well as outdoor climatic thermal comfort. Here, we use U.S. Climate Normals developed by NOAA based on weather station observations along with Climate Model Intercomparison Project phase 5 (CMIP5) multi-model ensemble simulations. We add the projected change in heating and cooling degree-days based on the climate models to the estimates based on the NOAA U.S. Climate Normals to project future heating and cooling degree-days. We find locations with the lowest and highest combined index of cooling (CDDs) and heating degree-days (HDDs) for the historical period (1981 - 2010) and future period (2080 - 2099) under the Representation Concentration Pathway 8.5 (RCP8.5) climate change scenario. Our results indicate that in both time frames and among the lower 48 states, coastal areas in the West and South California will have the smallest degree-day sum (CDD + HDD), and hence from a climatic perspective become the best candidates for residential real estate. The Rocky Mountains region in Wyoming, in addition to northern Minnesota and North Dakota, will have the greatest CDD + HDD. While global warming is projected to reduce the median heating and cooling demand (- 5%) at the end of the century, CDD + HDD will decrease in the North, with an opposite effect in the South. This work could be helpful in deciding where to live in the United States based on present and future thermal comfort, and could also provide a basis for estimates of changes in heating and cooling energy demand.

  2. Expression of manganese peroxidase by Lentinula edodes and Lentinula boryana in solid state and submerged system fermentation.

    PubMed

    Hermann, Katia L; Costa, Alessandra; Helm, Cristiane V; De Lima, Edson A; Tavares, Lorena B B

    2013-09-01

    The production of ethanol from lignocellulosic biomass is referred as a second generation biofuel, whose processing is one of the most promising technologies under development. There are few available studies on the use of enzymes produced by fungi as active for the biodegradation of lignocellulosic biomass. However, the manganese peroxidase (MnP) enzyme presents high potential to degrade lignin and the basidiomycetes are the major producers of this oxidase. Thus, this study aimed at evaluating the ability of fungi Lentinula edodes and Lentinula boryana to produce this enzyme when cultivated in submerged fermentation system (SS) and also in solid-state fermentation system (SSF) containing Eucalyptus benthamii sawdust with or without corn cob meal. In the SS the greatest MnP expression occurred on the 25th day, being of 70 UI.L-1 for L. boryana and of 20 UI.L-1 for L. edodes. In the SSF, the best results were obtained on the 10th day for L. edodes, while for L. boryana it happened between the 20th and the 25th days, despite both species presented values close to 110 UI.L-1. Therefore, the results indicated that the studied fungi express the enzyme of interest and that its production is enhanced when cultivated in solid system.

  3. AGARD (Advisory Group for Aerospace Research & Development) Highlights 89/1

    DTIC Science & Technology

    1989-03-01

    State for Defence, Sefior Don Rafael de la Cruz Corcoll , at the end of which he summarised the aim of the day’s events, as follows: Mr Chairman...increasing our scientific and technical cooperation RAFAEL DE LA CRUZ Corcoll was born in Barcelona in 1945 and after graduating in Economics from... Corcoll , Spanish Secretary of State for Defence was presented with an AGARD plaque by the Chairman of AGARD, Rear Admiral Robert Geiger. Drinking a

  4. Landforms of the United States

    USGS Publications Warehouse

    Hack, John T.

    1969-01-01

    The United States contains a great variety of landforms which offer dramatic contrasts to a crosscountry traveler. Mountains and desert areas, tropical jungles and areas of permanently frozen subsoil, deep canyons and broad plains are examples of the Nation's varied surface. The present-day landforms the features that make up the face of the earth are products of the slow, sculpturing actions of streams and geologic processes that have been at work throughout the ages since the earth's beginning.

  5. Food Assistance: Efforts To Control Fraud and Abuse in the Child and Adult Care Food Program Should Be Strengthened. United States General Accounting Office Report to Congressional Committees.

    ERIC Educational Resources Information Center

    Robertson, Robert E.

    The Child and Adult Care Food Program provides over $1.5 billion in benefits annually to children and adults in day care. In order to address the longstanding problems of fraud and abuse present in the program, state agencies have been charged with the responsibility for implementing Food and Nutrition Service's (FNS) regulations to prevent and…

  6. Long-term studies with the Ariel 5 ASM. I - Hercules X-1, Vela X-1, and Centaurus X-3

    NASA Technical Reports Server (NTRS)

    Holt, S. S.; Kaluzienski, L. J.; Boldt, E. A.; Serlemitsos, P. A.

    1979-01-01

    Twelve hundred days of 3-6 keV X-ray data from Her X-1, Vela X-1, and Cen X-3 accumulated with the Ariel 5 All-Sky Monitor are interrogated. The binary periodicities of all three can be clearly observed, as can the 35 day variation of Her X-1, for which we can refine the period to 34.875 plus or minus 0.030 days. No such longer-term periodicity less than 200 days is observed from Vela X-1. The 26.6 days low-state recurrence period for Cen X-3 is not observed, but a 43.0 day candidate periodicity is found which may be consistent with the precession of an accretion disk in that system. The present results are illustrative of the long-term studies which can be performed on approximately 50 sources over a temporal base which will ultimately extend to at least 1800 days.

  7. Using Petitions To Teach Slavery.

    ERIC Educational Resources Information Center

    Freeman, Damon

    2003-01-01

    Presents a lesson for teaching students about slavery in the United States by using slavery petitions. Describes a lesson that spans over two class periods, explaining that on the first day students listen to an interview with Professor Loren Schweninger about the "Talking History" program. Includes reproductions of the petitions. (CMK)

  8. Punching Out.

    ERIC Educational Resources Information Center

    Hill, David

    2000-01-01

    Presents the story of the number one for-profit school in the United States, the Thomas A. Edison Charter Academy. Teachers had a heavier workload, but better pay and perks. Shortly after opening, many teachers were discontent with the long days and calendar, lack of follow through on promised benefits, and other issues. Reactions to this…

  9. Introduction to Norsk.

    ERIC Educational Resources Information Center

    Simonsen, Reidar G.

    This Norsk language unit is intended to introduce high school students in the United States to modern spoken Norwegian and to Norwegian culture. The document is presented in 18 chapters. Topics include greetings, family, speaking Norwegian, the alphabet, travel in Norway, parts of the country, telling time, pronouns and articles, days of the week,…

  10. Outreach event

    NASA Image and Video Library

    2012-05-30

    Stennis Space Center education program specialists Chris Copelan (l) and Joshua Finch provide a Working in Space presentation to Camp Dream Street participants during a May 30, 2012, visit to Utica, Miss. Dream Street is a five-day camp program for children with physical disabilities. Camp participants are primarily from Mississippi and surrounding states.

  11. The Texas Plan to Combat Mental Retardation.

    ERIC Educational Resources Information Center

    Governor's Advisory Committee on Mental Retardation Planning, Austin, TX.

    The Texas state plan of action against mental retardation is presented. Aspects considered include the evolution of the plan, the role of the health services, medical aspects of retardation, education and training, vocational rehabilitation and employment, and social welfare. Also surveyed are the following: residential and day care, manpower,…

  12. U. S. Forest Service American Chestnut Cooperators' Meeting

    Treesearch

    Clay H. Smith

    1981-01-01

    On January 8 and 9, 1980, a 2-day meeting of U.S. Forest Service American chestnut cooperators was held at Pipestem State Park, Pipestem, West Virginia. A total of 43 talks were given a t this meeting. All speakers provided short abstracts of their talks; these abstracts are presented here.

  13. A Bibliography for Chicano History.

    ERIC Educational Resources Information Center

    Meier, Matt S.; Rivera, Feliciano

    The principal objective of this bibliography is to provide the beginning student in Chicano history a selective list of items useful to understanding each of the major historical periods from the Mexican American's origins to the present day. The bibliography is arranged chronologically to include: books; some Federal, state, and local…

  14. On the Structure of the Present-Day Convergence

    ERIC Educational Resources Information Center

    Korotayev, Andrey; Zinkina, Julia

    2014-01-01

    Purpose: A substantial number of researchers have investigated the global economic dynamics of this time to disprove unconditional convergence and refute its very idea, stating the phenomenon of conditional convergence instead. However, most respective papers limit their investigation period with the early or mid-2000s. In the authors' opinion,…

  15. 78 FR 44593 - Notice of Inventory Completion: Washington State Parks and Recreation Commission, Olympia, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-24

    ... tribes or Native Hawaiian organizations, and has determined that there is a cultural affiliation between the human remains and present-day Indian tribes or Native Hawaiian organizations. Lineal descendants or representatives of any Indian tribe or Native Hawaiian organization not identified in this notice...

  16. Hispanic America to 1776. Globe Mosaic of American History.

    ERIC Educational Resources Information Center

    Lewin, Stephen, Ed.; And Others

    This textbook examines Spanish exploration, conquest, settlement, and colonization of present-day Mexico, United States, and the Caribbean, and the conflicts and exchanges resulting from culture contact between Spaniards and Native Americans. Chapters cover: (1) first contacts in the Caribbean, enslavement of Native Americans, arrival of African…

  17. Understanding Writing--Process, Skill and Product. Dissemination Report.

    ERIC Educational Resources Information Center

    Ohio State Dept. of Education, Columbus.

    This conference proceedings reflects the substance of the 3-day Conference on Written Communication, sponsored by the Ohio Department of Education and designed to provide professional growth opportunities for more than 350 school administrators, teachers, and university and state department personnel. The papers in the proceedings present a review…

  18. Organizing to Manage Base-Level Service Contracts in the 1990s.

    DTIC Science & Technology

    1986-04-01

    management of service contracts is the present day organizational structure. The structure is flawed and violates basic principles of management . Until the...are classic principles of management . To state the principle I will quote Ernest Dale: "Authority should be commensurate with responsibility. That is

  19. Predicting Mood Changes in Bipolar Disorder through Heartbeat Nonlinear Dynamics.

    PubMed

    Valenza, Gaetano; Nardelli, Mimma; Lanata', Antonio; Gentili, Claudio; Bertschy, Gilles; Kosel, Markus; Scilingo, Enzo Pasquale

    2016-04-20

    Bipolar Disorder (BD) is characterized by an alternation of mood states from depression to (hypo)mania. Mixed states, i.e., a combination of depression and mania symptoms at the same time, can also be present. The diagnosis of this disorder in the current clinical practice is based only on subjective interviews and questionnaires, while no reliable objective psychophysiological markers are available. Furthermore, there are no biological markers predicting BD outcomes, or providing information about the future clinical course of the phenomenon. To overcome this limitation, here we propose a methodology predicting mood changes in BD using heartbeat nonlinear dynamics exclusively, derived from the ECG. Mood changes are here intended as transitioning between two mental states: euthymic state (EUT), i.e., the good affective balance, and non-euthymic (non-EUT) states. Heart Rate Variability (HRV) series from 14 bipolar spectrum patients (age: 33.439.76, age range: 23-54; 6 females) involved in the European project PSYCHE, undergoing whole night ECG monitoring were analyzed. Data were gathered from a wearable system comprised of a comfortable t-shirt with integrated fabric electrodes and sensors able to acquire ECGs. Each patient was monitored twice a week, for 14 weeks, being able to perform normal (unstructured) activities. From each acquisition, the longest artifact-free segment of heartbeat dynamics was selected for further analyses. Sub-segments of 5 minutes of this segment were used to estimate trends of HRV linear and nonlinear dynamics. Considering data from a current observation at day t0, and past observations at days (t1, t2,...,), personalized prediction accuracies in forecasting a mood state (EUT/non-EUT) at day t+1 were 69% on average, reaching values as high as 83.3%. This approach opens to the possibility of predicting mood states in bipolar patients through heartbeat nonlinear dynamics exclusively.

  20. 75 FR 24371 - Loyalty Day, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... Day, 2010 By the President of the United States of America A Proclamation On July 4, 1776, after the... ``Loyalty Day.'' On this day, we honor the legacy of these United States, and we remember all those who have..., do hereby proclaim May 1, 2010, as Loyalty Day. This Loyalty Day, I call upon the people of the...

  1. Discussion of Yellow Starthistle Response to Photosynthetic Irradiance, Photoperiod, and CO2

    NASA Technical Reports Server (NTRS)

    Bubenheim, David

    2017-01-01

    Yellow Starthistle (Centaurea solstitialis) is a native annual weed of Eurasia and since introduction into the United STates has become an invasive and noxious weed. It grows in a rosette habit during the vegetative state and usually bolts in summer to produce a large and branched flowering stem. Time to flowering in Yellow Starthistle has been attributed to photoperiod, nitrogen nutrition, temperature, and water stress. We executed a series of studies to investigate the role of light, both photoperiod and photosynthetic photon flux, on flowering and development in Yellow Starthistle. Treatments were presented in 4 ways: 1) varying day length with constant photosynthetic photon flus (PPF) providing increasing daily integrated Photosynthetic Photon (PP) exposure with longer day lengths 2) varying day length while adjusting PPF to maintain daily PP exposure for all treatments 3) extending photoperiod treatments beyond common 12-h photosynthetic period with low light levels to maintain both PPF and daily PP across all treatments4)reciprocal exchange of plant among photoperiod treatments Yellow Starthistle appears to be a long-day plant with a critical day length requirement between 14-h and 16-h to induce transition from vegetative to floral stages in development. PPF and daily absorbed photons did not affect time to vegetative floral stage transition, but did affect factors such as biomass accumulation and canopy parameters such as specific leaf mass. Reciprocal exchange of plants between floral inducing and inhibiting photoperiod treatments, starting at 2-weeks post germination, had no effect on to flower. Flowering was determined by photoperiod experienced during the first 2-weeks (or less) post germination.Yellow Starthistle net photosynthetic response to elevated atmospheric CO2 concentrations over a range of photosynthetically active radiation flux rates and temperatures will also be presented and discussed.

  2. 78 FR 46421 - Proposed Information Collection (Per Diem for Nursing Home Care of Veterans in State Homes; Per...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... Diem for Nursing Home Care of Veterans in State Homes; Per Diem for Adult Day Care of Veterans in State... information needed to ensure that nursing home and adult day health care facilities are providing high quality... State homes providing nursing home and adult day health services care to Veterans. VA requires...

  3. Happy Now, Tired Later? Extraverted and Conscientious Behavior Are Related to Immediate Mood Gains, but to Later Fatigue.

    PubMed

    Leikas, Sointu; Ilmarinen, Ville-Juhani

    2017-10-01

    Experience sampling studies on Big Five-related behavior show that people display the whole spectrum of each trait in their daily behavior, and that desirable Big Five states-especially state Extraversion-are related to positive mood. However, other research lines suggest that extraverted and conscientious behavior may be mentally depleting. The present research examined this possibility by extending the time frame of the measured personality processes. A 12-day experience sampling study (N = 48; observations = 2,328) measured Big Five states, mood, stress, and fatigue five times a day. Extraverted and conscientious behavior were concurrently related to positive mood and lower fatigue, but to higher fatigue after a 3-hour delay. These relations were not moderated by personality traits. The relation between extraverted behavior and delayed fatigue was mediated by the number of people the person had encountered. Whether the person had a goal mediated the relation between conscientious behavior and delayed fatigue. Extraverted and conscientious behavior predict mental depletion after a 3-hour delay. The results help reconcile previous findings regarding the consequences of state Extraversion and provide novel information about the consequences of state Conscientiousness. © 2016 Wiley Periodicals, Inc.

  4. Night and day variations of sleep in patients with disorders of consciousness.

    PubMed

    Wislowska, Malgorzata; Del Giudice, Renata; Lechinger, Julia; Wielek, Tomasz; Heib, Dominik P J; Pitiot, Alain; Pichler, Gerald; Michitsch, Gabriele; Donis, Johann; Schabus, Manuel

    2017-03-21

    Brain injuries substantially change the entire landscape of oscillatory dynamics and render detection of typical sleep patterns difficult. Yet, sleep is characterized not only by specific EEG waveforms, but also by its circadian organization. In the present study we investigated whether brain dynamics of patients with disorders of consciousness systematically change between day and night. We recorded ~24 h EEG at the bedside of 18 patients diagnosed to be vigilant but unaware (Unresponsive Wakefulness Syndrome) and 17 patients revealing signs of fluctuating consciousness (Minimally Conscious State). The day-to-night changes in (i) spectral power, (ii) sleep-specific oscillatory patterns and (iii) signal complexity were analyzed and compared to 26 healthy control subjects. Surprisingly, the prevalence of sleep spindles and slow waves did not systematically vary between day and night in patients, whereas day-night changes in EEG power spectra and signal complexity were revealed in minimally conscious but not unaware patients.

  5. STS-74 flight day 6

    NASA Astrophysics Data System (ADS)

    1995-11-01

    On this sixth day of the STS-74 mission, the flight crew, Cmdr. Kenneth Cameron, Pilot James Halsell, and Mission Specialists William McArthur, Jerry Ross, and Chris Hatfield and the Mir 20 cosmonauts, Cmdr. Yuri Gidzenko, Flight Engineer Sergei Avdeyev, and Cosmonaut-Researcher (ESA) Thomas Reiter, were greeted and briefly interviewed by the Secretary General of the United Nations, Boutros Boutros-Ghali, on the 50th anniversary of the United Nations via a radio satellite hookup. An additional interview with other journalists from different areas of the United States and Canada was also presented.

  6. An outbreak of scalp white piedra in a Brazilian children day care.

    PubMed

    Roselino, Ana Maria; Seixas, Ana Beatriz; Thomazini, José A; Maffei, Claudia M L

    2008-01-01

    White piedra is a superficial mycosis caused by Trichosporon spp. that affects the hair shaft of any part of the body. It is presented an outbreak of scalp white piedra seen in 5.8% of the children frequenting a day care in Northeastern of São Paulo State, Brazil. Mycological exam and culture identified T. cutaneum in all five cases, and scanning electron microscopy of nodules around hair shaft infected by Trichosporon spp. is demonstrated comparing them with those of black piedra and with nits of Pediculous capitis.

  7. Shah-Waardenburg syndrome: a case highlighting the importance of a holistic approach to assessing a child.

    PubMed

    Patil, Amogh; Prathyusha, Lanka; Patil, Muganagowda

    2017-12-22

    We present the case of a 45-day-old child with the chief complaint of failure to pass stools for 10 days. After initial investigation, the patient was found to have Hirschsprung's disease. However, with further examination and analysis, the extremely rare diagnosis of type 4 Waardenburg syndrome was made (also known as Shah-Waardenburg syndrome or Waardenburg-Hirschsprung's disease). © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  8. Acute withdrawal but not long-term withdrawal from methamphetamine affects sexual behavior in female rats.

    PubMed

    Thibodeau, Rachel B; Ornelas, Laura C; Romero, Jordan; Memos, Nicoletta; Scheible, Matthew; Avila, Alfred; Schumacher, Abby; Navarro, April; Zimmermann, Karen; Cuenod, Bethany A; Frohardt, Russell J; Guarraci, Fay A

    2013-02-01

    The present study was designed to investigate the long-term effects of repeated methamphetamine (MA) exposure on sexual motivation in female rats tested after a period of drug abstinence. In Experiment 1, female subjects received three injections of MA (1.0mg/kg/day, every other day) or saline and were tested for paced mating behavior (where females could control the receipt of sexual stimulation from one male rat) 21 days after their last injection. In Experiment 2, female subjects received 12 consecutive injections of MA (1.0mg/kg/day) or saline and were tested for mate choice (where females could control the receipt of sexual stimulation from two male rats simultaneously) 6 days after their last injection. Experiment 3 was identical to Experiment 2 except that female subjects received no baseline mating test and were tested for mate choice 24h and 6 days after their last injection. Open field tests were conducted in each experiment to measure locomotor activity after repeated exposure to MA. Although repeated MA exposure increased locomotor activity, mating behavior was not facilitated after either a short (6 days) or long (21 days) period of drug abstinence. Nevertheless, sexual behavior was disrupted during the 24h acute withdrawal period. Therefore, although the present study found no evidence of cross-sensitization between female sexual behavior and MA after either a short or a long period of drug abstinence, sexual behavior in sexually naïve female rats is sensitive to the depressive state associated with acute withdrawal from MA. In conclusion, the results of the present study suggest that MA acts differently from other psychomotor stimulants, and that the effects of MA withdrawal on sexual behavior differ between male and female rats. Copyright © 2012 Elsevier Inc. All rights reserved.

  9. [Follow-up of a 16-year-old adolescent with early-onset schizophrenia and catatonic symptoms].

    PubMed

    Menard, M-L; Yagoubi, F; Drici, M; Lavrut, T; Askenazy, F

    2013-05-01

    The aim of this paper is to underline the need of a systematic monitoring (1) of atypical antipsychotics and (2) of catatonic symptoms in child psychiatry. We present in this paper the clinical history of a 16-year-old adolescent inpatient needing a prescription of atypical antipsychotic drug. We present the most relevant results of our clinical monitoring over 7 months. A 16-year-old Caucasian male adolescent, by the name of Paul, was admitted in August 2009 to an Adolescent University Psychiatry Unit for an acute psychotic disorder. On admission, he presented paranoid delusion, auditory hallucinations and impulsive movements. The score on the Bush-Francis Catatonia Rating Scale (BFCRS) was 17 (the threshold score for the diagnosis of catatonic symptoms is 2). Laboratory tests showed the lack of blood toxic levels, creatine phosphokinase (CPK) level was 684 IU/L. Paul was treated with clonazepam (0.05 mg/kg/d). This particular day was considered to be day #1 of the clinical drug monitoring. Immediately after, regular follow-up of catatonic symptoms was performed. On day #15, the CPK level returned to normal with improvement of clinical catatonia but with still a score of 4 on the BFCRS scale. Auditory hallucinations and delusion persisted. Risperidone treatment was begun (1mg/d and 1.5mg/d after 24 hours), associated with oral clonazepam (0.05 mg/kg/d). On day #17, after 48 hours of improvement of delusion, the catatonic symptoms rapidly worsened. Risperidone was stopped; Paul was transferred to intensive care where he was treated with clonazepam IV (0.1mg/kg/d). The score on BFCRS scale was 20, Paul presented no fever and the CPK level was below 170 IU/L. The diagnosis was a relapse of the catatonic episode, which was caused by the administration of risperidone. On day #24, no improvement in the state of catatonia was obtained. The treatment was changed with the following combination of medicine: clonazepam (0.1mg/kg/d)-lorazepam (5mg/d)-carbamazepine (10mg/kg/d). With this combination, the state of catatonia improved quickly and on day #31, he was transferred to the adolescent psychiatry unit. However, delusion and hallucinations persisted; a treatment with olanzapine was started at 5mg/d and then progressively increased to 20mg/d for 10 days. On day #115, after 3 months with olanzapine, no improvement of the hallucinatory and delusional symptoms was observed; the diagnosis of early-onset refractory schizophrenia was established. The Therapeutic Drug Monitoring (TDM) confirmed the good compliance; clozapine was introduced and progressively increased up to 250 mg/d. On day #199, after 3 months under clozapine (250 mg/d), the speech was coherent and delusion was rare. During this period, no relapse of the catatonic state was observed. In this case, the BFCRS scale was sensitive to catatonic symptom diagnosis. CPK levels vary differently for each atypical antipsychotic and are not a specific complication indicator. In complex cases, the TDM seems useful when choosing atypical antipsychotics. The association of two benzodiazepines (clonazepam-lorazepam) with carbamazepin allowed the improvement of catatonic symptoms. Plasma levels of atypical antipsychotics helped the practitioner in deciding the type of care required: plasma levels confirmed the patient's treatment adherence and thus reinforced the choice of clozapine. Copyright © 2012 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.

  10. Quantum key distribution with passive decoy state selection

    NASA Astrophysics Data System (ADS)

    Mauerer, Wolfgang; Silberhorn, Christine

    2007-05-01

    We propose a quantum key distribution scheme which closely matches the performance of a perfect single photon source. It nearly attains the physical upper bound in terms of key generation rate and maximally achievable distance. Our scheme relies on a practical setup based on a parametric downconversion source and present day, nonideal photon-number detection. Arbitrary experimental imperfections which lead to bit errors are included. We select decoy states by classical postprocessing. This allows one to improve the effective signal statistics and achievable distance.

  11. 75 FR 35951 - World Refugee Day, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-23

    ... Refugee Day, 2010 By the President of the United States of America A Proclamation On World Refugee Day, we... Refugee Day, we recommit to ensuring that the blessings of liberty and opportunity are available to all... hereby proclaim June 20, 2010, as World Refugee Day. I call upon all the people of the United States to...

  12. Plio-Quaternary stress states in NE Iran: Kopeh Dagh and Allah Dagh-Binalud mountain ranges

    NASA Astrophysics Data System (ADS)

    Shabanian, Esmaeil; Bellier, Olivier; Abbassi, Mohammad R.; Siame, Lionel; Farbod, Yassaman

    2010-01-01

    NE Iran, including the Kopeh Dagh and Allah Dagh-Binalud deformation domains, comprises the northeastern boundary of the Arabia-Eurasia collision zone. This study focuses on the evolution of the Plio-Quaternary tectonic regimes of northeast Iran. We present evidence for drastic temporal changes in the stress state by inversion of both geologically and seismically determined fault slip vectors. The inversions of fault kinematics data reveal distinct temporal changes in states of stress during the Plio-Quaternary (since ˜ 5 Ma). The paleostress state is characterized by a regional transpressional tectonic regime with a mean N140 ± 10°E trending horizontal maximum stress axis ( σ1). The youngest (modern) state of stress shows two distinct strike-slip and compressional tectonic regimes with a regional mean of N030 ± 15°E trending horizontal σ1. The change from the paleostress to modern stress states has occurred through an intermediate stress field characterized by a mean regional N trending σ1. The inversion analysis of earthquake focal mechanisms reveals a homogeneous, transpressional tectonic regime with a regional N023 ± 5°E trending σ1. The modern stress state, deduced from the youngest fault kinematics data, is in close agreement with the present-day stress state given by the inversions of earthquake focal mechanisms. According to our data and the deduced results, in northeast Iran, the Arabia-Eurasia convergence is taken up by strike-slip faulting along NE trending left-lateral and NNW trending right-lateral faults, as well as reverse to oblique-slip reverse faulting along NW trending faults. Such a structural assemblage is involved in a mechanically compatible and homogeneous modern stress field. This implies that no strain and/or stress partitioning or systematic block rotations have occurred in the Kopeh Dagh and Allah Dagh-Binalud deformation domains. The Plio-Quaternary stress changes documented in this paper call into question the extrapolation of the present-day seismic and GPS-derived deformation rates over geological time intervals encompassing tens of millions of years.

  13. 77 FR 45719 - Proposed Information Collection (Per Diem for Nursing Home Care of Veterans in State Homes; Per...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-01

    ... Diem for Nursing Home Care of Veterans in State Homes; Per Diem for Adult Day Care of Veterans in State... information needed to ensure that nursing home and adult day health care facilities are providing high quality... per diem to State homes providing nursing home and adult day health services care to Veterans. VA...

  14. Solving Tomorrow's Problems Today? Daily Anticipatory Coping and Reactivity to Daily Stressors.

    PubMed

    Neupert, Shevaun D; Ennis, Gilda E; Ramsey, Jennifer L; Gall, Agnes A

    2016-07-01

    The present study examined the day-to-day fluctuation of state-like anticipatory coping (coping employed prior to stressors) and how these coping processes relate to important outcomes for older adults (i.e., physical health, affect, memory failures). Forty-three older adults aged 60-96 (M = 74.65, SD = 8.19) participated in an 8-day daily diary study of anticipatory coping, stressors, health, affect, and memory failures. Participants reported anticipatory coping behaviors on one day with respect to 6 distinct stressor domains that could occur the following day. Multilevel models indicated that anticipatory coping changes from day to day and within stressor domains. Lagged associations suggested that yesterday's anticipatory coping for potential upcoming arguments is related to today's physical health and affect. Increased stagnant deliberation is associated with reduced cognitive reactivity (i.e., fewer memory failures) to arguments the next day. Taken together, these findings suggest that anticipatory coping is dynamic and associated with important daily outcomes. © The Author 2015. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  15. Arthrobacter globiformis and its bacteriophage in soil

    NASA Technical Reports Server (NTRS)

    Casida, L. E., Jr.; Liu, K.-C.

    1974-01-01

    An attempt was made to correlate bacteriophages for Arthrobacter globiformis with soils containing that bacterium. The phages were not detected unless the soil was nutritionally amended (with glucose or sucrose) and incubated for several days. Phage was continuously produced after amendment without the addition of host Arthrobacter. These results indicate that the bacteriophage is present in a masked state and that the bacteria are present in an insensitive form which becomes sensitive after addition of nutrient.

  16. Charting a Course: Social Studies for the 21st Century. A Report of the Curriculum Task Force of the National Commission on Social Studies in the Schools.

    ERIC Educational Resources Information Center

    American Historical Association, Washington, DC.

    This report by the Curriculum Task Force represents its considered conclusion about general reform (K-12) of the social studies curriculum in the United States. It presents a balanced and comprehensive curriculum program adapted to the needs of present day society and suggests direction for the future. Part 1 discusses the recommended social…

  17. Past- and present-day Madden-Julian Oscillation in CNRM-CM5

    NASA Astrophysics Data System (ADS)

    Song, Eun-Ji; Seo, Kyong-Hwan

    2016-04-01

    Madden-Julian Oscillation (MJO) in the past (nineteenth century) and present day (twentieth century) is examined using preindustrial and historical experiments of Centre National de Recherches Météorologiques-Coupled Models, version 5 (CNRM-CM5) in Coupled Model Intercomparison Project Phase 5 (CMIP5). The present-day MJO is stronger than the past MJO by 33% and it is ~10% more frequent. In particular, the MJO phases 4-7 signifying deep convection situated over the Maritime continent and western Pacific (WP) are considerably enhanced. These changes are due mainly to greenhouse gas forcing with little impact from nature forcing. Dynamical mechanisms for this change are investigated. A peculiar strengthening of MJO over WP comes from increased basic-state sea surface temperature (SST) over the Central Pacific (CP) and EP. The increase in precipitation over WP results from both the response to enhanced SST over CP and the inverted Walker circulation induced by the EP and CP SST increase. The latter causes a pair of anticyclonic Rossby waves straddling the equator, leading to moisture convergence over WP.

  18. Antenatal Bartter syndrome presenting with vomiting and constipation mimicking subacute intestinal obstruction in a 20-day-old neonate.

    PubMed

    Abdelgadir, Ibtihal Siddiq; Elgharbawy, Fawzia; Salameh, Khalil Mohamad; Juma, Baha Eldin

    2017-11-14

    Antenatal Bartter syndrome is a rare condition that can present with different clinical features. These features include early onset maternal polyhydramnios, failure to thrive, prematurity and nephrocalcinosis.We are presenting this 20-day-old girl who had an antenatal history of polyhydramnios. She developed persistent non-bilious vomiting that was associated with constipation soon after birth. She presented with failure to thrive and features suggestive of intestinal obstruction. On the initial evaluation, she was noted to have hypokalaemic, hyponatraemic metabolic alkalosis. The initial work-up was done to exclude surgical and renal causes of her presentation, and the diagnosis was confirmed by gene analysis to be type III-classic Bartter syndrome. She was closely monitored for her growth and development with the appropriate salt replacement therapy. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  19. Using climate model simulations to assess the current climate risk to maize production

    NASA Astrophysics Data System (ADS)

    Kent, Chris; Pope, Edward; Thompson, Vikki; Lewis, Kirsty; Scaife, Adam A.; Dunstone, Nick

    2017-05-01

    The relationship between the climate and agricultural production is of considerable importance to global food security. However, there has been relatively little exploration of climate-variability related yield shocks. The short observational yield record does not adequately sample natural inter-annual variability thereby limiting the accuracy of probability assessments. Focusing on the United States and China, we present an innovative use of initialised ensemble climate simulations and a new agro-climatic indicator, to calculate the risk of severe water stress. Combined, these regions provide 60% of the world’s maize, and therefore, are crucial to global food security. To probe a greater range of inter-annual variability, the indicator is applied to 1400 simulations of the present day climate. The probability of severe water stress in the major maize producing regions is quantified, and in many regions an increased risk is found compared to calculations from observed historical data. Analysis suggests that the present day climate is also capable of producing unprecedented severe water stress conditions. Therefore, adaptation plans and policies based solely on observed events from the recent past may considerably under-estimate the true risk of climate-related maize shocks. The probability of a major impact event occurring simultaneously across both regions—a multi-breadbasket failure—is estimated to be up to 6% per decade and arises from a physically plausible climate state. This novel approach highlights the significance of climate impacts on crop production shocks and provides a platform for considerably improving food security assessments, in the present day or under a changing climate, as well as development of new risk based climate services.

  20. 76 FR 58034 - Notice of Inventory Completion: Thomas Burke Memorial Washington State Museum, University of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-19

    ... indicates that the cultural items were found in connection with the human remains. The cultural items are... Museum) has completed an inventory of human remains and associated funerary objects, in consultation with... human remains and associated funerary objects and present-day Indian Tribes. Representatives of any...

  1. Corrections in Montana: A Consultation on Corrections in Montana.

    ERIC Educational Resources Information Center

    Montana State Advisory Committee to the U.S. Commission on Civil Rights, Helena.

    The findings and recommendations of a two-day conference on the civil and human rights of inmates of Montana's correctional institutions are contained in this report. The views of private citizens and experts from local, state, and federal organizations are presented in edited form under seven subject headings: existing prison reform legislation,…

  2. Institutional Roles for In-Service Education of School Administrators.

    ERIC Educational Resources Information Center

    Lynch, Patrick D., Ed.; Blackstone, Peggy L., Ed.

    This document is a compilation of papers read at a 4-day conference attended by 60 participants from throughout the United States. Chapters include (1) "In-Service Education of School Administrators: Background, Present Status, and Problems," by Robert B. Howsam; (2) "Notes on Institutional Relationships in the In-Service Education of the…

  3. Evaluation and Dissemination of the Electrical Power Engineering Technology Curriculum Model. Final Report.

    ERIC Educational Resources Information Center

    McNeill, Perry R.; And Others

    Described is a project initiated to evaluate and disseminate the Electrical Power Engineering Technology Curriculum developed at Oklahoma State University. The objective of the evaluation phase, to have the original model curriculum evaluated by both present and potential employers, was accomplished in a two-day workshop with participation of…

  4. Zur Soziolinguistik in der Bundesrepublik Deutschland (Sociolinguistics in the Federal Republic of Germany)

    ERIC Educational Resources Information Center

    Jachnow, Helmut

    1975-01-01

    Traces the history of sociolinguistic studies in West Germany from the early nineteenth century with Humboldt and reports on the state and purposes of sociolinguistic studies in present-day Federal Republic of Germany. Available from Liber Laeromedel, Box 1205, S-22105 Lund, Sweden (Text is in German.) (TL)

  5. World Inequality: Social and Economic Data for Selected Developing Countries.

    ERIC Educational Resources Information Center

    Social Education, 1998

    1998-01-01

    Presents a chart of socioeconomic data for 38 developing countries and the United States. Includes statistics on GNP per capita, percent of people living on less than one dollar a day, under-age-5 mortality rate, percent of population without access to safe water, and total adult-literacy rate. (DSK)

  6. 78 FR 59966 - Notice of Inventory Completion: Michigan State Police, Jackson Post, Jackson, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ... Indian tribes or Native Hawaiian organizations, and has determined that there is no cultural affiliation between the human remains and any present-day Indian tribes or Native Hawaiian organizations. Representatives of any Indian tribe or Native Hawaiian organization not identified in this notice that wish to...

  7. 78 FR 59956 - Notice of Inventory Completion: Thomas Burke Memorial Washington State Museum, University of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ... organizations, and have determined that there is a cultural affiliation between the human remains and associated funerary objects and present-day Indian tribes or Native Hawaiian organizations. Lineal descendants or representatives of any Indian tribe or Native Hawaiian organization not identified in this notice that wish to...

  8. 78 FR 59963 - Notice of Inventory Completion: Thomas Burke Memorial Washington State Museum, University of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ... organizations, and have determined that there is a cultural affiliation between the human remains and associated funerary objects and present-day Indian tribes or Native Hawaiian organizations. Lineal descendants or representatives of any Indian tribe or Native Hawaiian organization not identified in this notice that wish to...

  9. 78 FR 59954 - Notice of Inventory Completion: Michigan State Police, Mount Pleasant Post, Mount Pleasant, MI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ... tribes or Native Hawaiian organizations, and has determined that there is a cultural affiliation between the human remains and present- day Indian tribes or Native Hawaiian organizations. Lineal descendants or representatives of any Indian tribe or Native Hawaiian organization not identified in this notice...

  10. Fire in the forest

    Treesearch

    James M. Saveland

    1995-01-01

    From ancient philosophies to present day science, the ubiquity of change and the process of transformation are core concepts. The primary focus of a recent white paper on disturbance ecology is summed up by the Greek philosopher Heraclitus who stated, "Nothing is permanent but change." Disturbance processes, such as fire, provide a window into the emerging...

  11. A COMPARATIVE STUDY OF DAY CLASS VS. INSTITUTIONALIZED EDUCABLE RETARDATES.

    ERIC Educational Resources Information Center

    REYNOLDS, MAYNARD C.; STUNKARD, CLAYTON L.

    THE PRESENT STUDY REPRESENTS AN EXTENSION OF A STUDY WHICH DEALT WITH THE LATER ADJUSTMENT OF INDIVIDUALS DISCHARGED FROM A STATE INSTITUTION FOR THE MENTALLY RETARDED. THIS EFFORT REWORKED AVAILABLE DATA TO DEVELOP A MORE EFFICIENT TECHNIQUE OF PREDICTION AND TO STUDY FURTHER INTERACTIONS AMONG THE VARIOUS CHARACTERISTICS OF THE GROUP. IN…

  12. The Spiritual and Moral Education of Russia's School Students

    ERIC Educational Resources Information Center

    Daniliuk, A. Ia.; Kondakov, A. M.; Tishkov, V. A.

    2010-01-01

    This article discusses the new draft of the Federal State Standards of General Education which designates spiritual and moral upbringing as a key task of present-day education. In accordance with the Standards' requirements, the structure of the basic educational program shall, in addition to the fundamental nucleus of the content of the…

  13. Corporate Sponsored Child Care: Options and Advantages.

    ERIC Educational Resources Information Center

    Sallee, Alvin L.

    To further understanding of the complex issues regarding the provision of day care services, this paper presents an historical overview of national child care policy in the United States, and discusses the dimensions of working families' need for child care; the central policy issue of the relationship between work and the family; and incentives,…

  14. Aging in China.

    ERIC Educational Resources Information Center

    Sheppard, Harold L.; Streib, Gordon F.

    This document consists of facts and impressions gathered during 1984, in the course of an 18-day visit to the Peoples Republic of China by a team of epidemiologists and gerontologists from the United States. The major portion of the paper presents demographic, economic, and social perspectives on aging in China. It is noted that China remains a…

  15. Children's Rights: Countering the Opposition.

    ERIC Educational Resources Information Center

    Starr, R. H., Jr.; And Others

    The problems of enacting and implementing child advocacy laws at State and Federal levels are presented along with two cases which illustrate these problems and point to the advocacy role that psychologists can perform. The first case deals with the use of corporal punishment in family day care homes in Michigan. In 1974, rules against corporal…

  16. The Historical Development of Educational Assessment in Chile: 1810-2014

    ERIC Educational Resources Information Center

    Gysling, Jacqueline

    2016-01-01

    This article examines the historical development of the state's actions in educational assessment in Chile from the nineteenth century to the present day, based on the analysis of governmental decrees and regulations related to assessment, and their variability over time. The research identifies six distinctive periods, each of which expresses a…

  17. Quality Systems: Lessons from Early Efforts to Disseminate the Youth PQA

    ERIC Educational Resources Information Center

    Akiva, Tom; Yohalem, Nicole

    2006-01-01

    During 2006, High/Scope worked with the Forum to provide training and technical assistance to several state and regional networks which are building quality improvement and accountability systems. In each community, High/Scope staff presented to local decision-makers and provided one- or two-day pilot training workshops for parishioners and…

  18. 76 FR 35087 - Flag Day and National Flag Week, 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-15

    ... United States of America A Proclamation On June 14, 1777, the Second Constitutional Congress adopted a... founding colonies. The stars were set upon a blue field, in the words of the Congress's resolution... faced, the American flag has been ever present. It has flown on our ships and military bases around the...

  19. Muncie Remembers That Day of Infamy.

    ERIC Educational Resources Information Center

    Brant, Heather; And Others

    This document presents an oral history project in which 34 residents of Munice, Indiana were interviewed about their experiences and memories of the Japanese attack on Pearl Harbor, December 7, 1941. The project was conducted by the members of an Honors United States History class at Munice Southside High School. The students designed the…

  20. American History. Computer Programs.

    ERIC Educational Resources Information Center

    Lengel, James G.

    1983-01-01

    THE FOLLOWING IS THE FULL TEXT OF THIS DOCUMENT: Seven interactive computer programs are available to help with the study of American History. They cover the period of the 17th century up through the present day, and involve a variety of approaches to instruction. These programs were conceived and programmed by Jim Lengel, a former state social…

  1. 76 FR 28806 - Notice of Inventory Completion: Thomas Burke Memorial Washington State Museum, University of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-18

    ... Museum), University of Washington, has completed an inventory of human remains and associated funerary... affiliation between the human remains and associated funerary objects and a present-day Indian tribe. Representatives of any Indian tribe that believes itself to be culturally affiliated with the human remains and...

  2. The Four-Day School Week. Issuegram 14.

    ERIC Educational Resources Information Center

    Bauman, Paul

    The four-day week is a popular way to improve the quality of education and save energy costs in rural districts. The four-day week is structured as a lengthened day or school year. Thirteen states have districts operating on four-day calendars. State laws and education agency regulations require districts to evaluate the effect of four-day…

  3. 25 CFR 291.9 - What must the Secretary do at the end of the 60-day comment period if the State offers an...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... comment period if the State offers an alternative proposal for Class III gaming procedures? 291.9 Section... GAMING PROCEDURES § 291.9 What must the Secretary do at the end of the 60-day comment period if the State offers an alternative proposal for Class III gaming procedures? Within 30 days of receiving the State's...

  4. Shallow transient liquid water environments on present-day mars, and their implications for life

    NASA Astrophysics Data System (ADS)

    Jones, Eriita G.

    2018-05-01

    The identification and characterisation of subsurface liquid water environments on Mars are of high scientific interest. Such environments have the potential to support microbial life, and, more broadly, to develop our understanding of the habitability of planets and moons beyond Earth. Given our current state of knowledge of life on Earth, three pre-requisites are necessary for an environment to be considered 'habitable' and therefore capable of supporting terrestrial-like life: energy, biogenic elements, and liquid water with a sufficiently high water activity. The surface of Mars today is predominately cold and dry, and any liquid water exposed to the atmosphere will vaporise or freeze on timescales of hours to days. These conditions have likely persisted for much of the last 10 million years, and perhaps longer. Despite this, briny liquid water flows (Recurrent Slope Linea) have been observed in a number of locations in the present-day. This review examines evidence from the Phoenix Lander (2008) and the Mars Science Laboratory (2012-current), to assess the occurrence of habitable conditions in the shallow Martian regolith. It will be argued that shallow, transient, liquid water brines are potentially habitable by microbial life, are likely a widespread occurrence on Mars, and that future exploration aimed at finding present-day habitable conditions and potential biology should 'follow the salt'.

  5. Dietary Intake, Eating Behaviors, and Diurnal Patterns of Salivary Cortisol and Alpha-Amylase Secretion Among Professional Young Adult Female Tennis Players.

    PubMed

    Filaire, Edith; Massart, Alain; Hua, Jiewen; Le Scanff, Christine

    2015-06-01

    The aims of study were to examine the eating behaviors among 26 professional female tennis players and to assess the diurnal patterns of stress hormones through the measurement of awakening and diurnal profiles of salivary alpha-amylase (sAA) and cortisol concentrations. Eating behaviors were assessed through three questionnaires (Eating Attitudes Test-26; Eating Disorders Inventory 2; and Body Shape Questionnaire), food intake by a 7-day diet record, and menstrual status by questionnaire. Perceived stress scale and anxiety state were also evaluated. Saliva samples were collected at awakening, 30 min, 60 min, and 12 hr post awakening after 6-days' rest. Forty-six percent of tennis players presented Disordered Eating attitudes (DE) (n = 12) with a lower body mass index, and higher state anxiety as compared with the group without DE. No differences in the Perceived Stress Scale scores were noted. Mean energy intake, protein and carbohydrates intakes were lower (p < .05) in the DE group as compared with the group without DE. Although in both groups, sAA concentrations presented a decrease in the first 30 min after awakening, and then progressively rose toward the afternoon, DE players exhibited reduced concentrations of the sAA with a decrease in its overall day secretion. Moreover, they showed a higher overall day secretion of salivary cortisol and a higher Cortisol Awakening Response. These results suggest that the activity of the sympathetic nervous system is impaired whereas the cortisol awakening response is enhanced. The long-term consequences of these modifications on health remain to be elucidated.

  6. Shot by a Gun … Missed by a Provider.

    PubMed

    Garcia, Eddie; Zaid, Abdul H; Calello, Diane P; McHugh, Lisa; Arzumanov, Grant; Asrar, Najaf; Sapin, Ari; Fless, Kristin G

    2018-04-01

    Botulism is a paralytic disease caused by the neurotoxin produced by Clostridium botulinum. The majority of cases are due to ingestion or injection drug use. Wound botulism from traumatic injury is exceedingly rare, with only one to two cases reported each year in the United States. A 27-year-old man presented to the Emergency Department with diplopia, dysphagia, and progressive weakness 10 days after sustaining a gunshot wound to his right lower leg. He had been evaluated for the same complaints at a different facility the day prior and was discharged. His wound appeared well-healing, but a high suspicion for wound botulism led to rapid consultation with the state Poison Control Center and the Centers for Disease Control and Prevention. The patient developed worsening respiratory insufficiency and required mechanical ventilation. Expeditious treatment with equine heptavalent botulinum antitoxin resulted in significant recovery of strength in 4 days. Serum toxin bioassay tested positive for botulinum neurotoxin type A. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Wound botulism now accounts for the majority of adult botulism in the United States. It should be considered in any patient with signs of neuromuscular disease and a recent injury, even if the wound appears uninfected. Published by Elsevier Inc.

  7. Monitoring environmental state of Alaskan forests with AIRSAR

    NASA Technical Reports Server (NTRS)

    Mcdonald, Kyle C.; Way, Jobea; Rignot, Eric; Williams, Cindy; Viereck, Les; Adams, Phylis

    1992-01-01

    During March 1988 and May 1991, the JPL airborne synthetic aperture radar, AIRSAR, collected sets of multi-temporal imagery of the Bonanza Creek Experimental Forest near Fairbanks, Alaska. These data sets consist of series of multi-polarized images collected at P-, L-, and C-bands each over a period of a few days. The AIRSAR campaigns were complemented with extensive ground measurements that included observations of both static canopy characteristics such as forest architecture as well as properties that vary on short term time scales such as canopy dielectric conditions. Observations exist for several stands of deciduous and coniferous species including white spruce (Picea glauca), black spruce (Picea mariana), and balsam poplar (Populus balsamifera). Although the duration of each campaign was fairly short, significant changes in environmental conditions caused notable variations in the physiological state of the canopies. During the 1988 campaign, environmental conditions ranged from unseasonably warm to more normal subfreezing temperatures. This permitted AIRSAR observations of frozen and thawed canopy states. During May 1991, ice jams that occurred along the river caused many stands to flood while the subsequent clearing of the river then allowed the waters to recede, leaving a snow covered ground surface. This allowed observations of several stands during both flooded and nonflooded conditions. Furthermore, the local weather varied from clear sunny days to heavy overcast days with some occurrence of rain. Measurements of leaf water potential indicated that this caused significant variations in canopy water status, allowing SAR observations of water stressed and unstressed trees. Mean backscatter from several stands is examined for the various canopy physiological states. The changes in canopy backscatter that occur as a function of environmental and physiological state are analyzed. Preliminary results of a backscatter signature modeling analysis are presented. The implications of using SAR to monitor canopy phenological state are addressed.

  8. Everyday eating experiences of chocolate and non-chocolate snacks impact postprandial anxiety, energy and emotional states.

    PubMed

    Martin, François-Pierre J; Antille, Nicolas; Rezzi, Serge; Kochhar, Sunil

    2012-06-01

    Social and psychological stressors are both a part of daily life and are increasingly recognized as contributors to individual susceptibility to develop diseases and metabolic disorders. The present study investigated how snacks differing in sensory properties and presentation can influence ratings of affect in consumers with different levels of dispositional anxiety. This study examines the relationships between a pre-disposition to anxiety and food using a repeated exposures design with three interspersed test days over a period of two weeks. The study was conducted on ninety free-living male (n = 28) and female (n = 62) Dutch participants aged between 18 and 35 years old, with a BMI between 18 and 25 kg/m(2) and different anxiety trait levels assessed using State-Trait Anxiety Inventory tests. The study was randomized by age, gender, anxiety trait score, and followed a parallel open design. Three test products: dark chocolate, a milk chocolate snack and crackers with cheese spread (control), which differed in composition, sensory properties and presentation, were evaluated. Changes in self-reported anxiety, emotion, and energetic states were assessed as a function of eating the snacks just after consumption and up to one hour. The repeated exposure design over a period of two weeks enabled the investigations of potential cumulative effects of regular consumption of the food products. The milk chocolate snack resulted in the decrease of anxiety in high anxiety trait subjects, whereas dark chocolate and cheese and crackers respectively improved the anxiety level and the energetic state of low anxiety trait participants. The mood effects were not altered with repeated exposure, and the magnitude of changes was similar on each test day, which illustrates the repeatability of the effects of the food on subjective measures of postprandial wellness.

  9. Everyday Eating Experiences of Chocolate and Non-Chocolate Snacks Impact Postprandial Anxiety, Energy and Emotional States

    PubMed Central

    Martin, François-Pierre J.; Antille, Nicolas; Rezzi, Serge; Kochhar, Sunil

    2012-01-01

    Social and psychological stressors are both a part of daily life and are increasingly recognized as contributors to individual susceptibility to develop diseases and metabolic disorders. The present study investigated how snacks differing in sensory properties and presentation can influence ratings of affect in consumers with different levels of dispositional anxiety. This study examines the relationships between a pre-disposition to anxiety and food using a repeated exposures design with three interspersed test days over a period of two weeks. The study was conducted on ninety free-living male (n = 28) and female (n = 62) Dutch participants aged between 18 and 35 years old, with a BMI between 18 and 25 kg/m2 and different anxiety trait levels assessed using State-Trait Anxiety Inventory tests. The study was randomized by age, gender, anxiety trait score, and followed a parallel open design. Three test products: dark chocolate, a milk chocolate snack and crackers with cheese spread (control), which differed in composition, sensory properties and presentation, were evaluated. Changes in self-reported anxiety, emotion, and energetic states were assessed as a function of eating the snacks just after consumption and up to one hour. The repeated exposure design over a period of two weeks enabled the investigations of potential cumulative effects of regular consumption of the food products. The milk chocolate snack resulted in the decrease of anxiety in high anxiety trait subjects, whereas dark chocolate and cheese and crackers respectively improved the anxiety level and the energetic state of low anxiety trait participants. The mood effects were not altered with repeated exposure, and the magnitude of changes was similar on each test day, which illustrates the repeatability of the effects of the food on subjective measures of postprandial wellness. PMID:22822453

  10. Palaeo-modeling of coastal salt water intrusion during the Holocene: an application to the Netherlands

    NASA Astrophysics Data System (ADS)

    Delsman, J. R.; Hu-a-ng, K. R. M.; Vos, P. C.; de Louw, P. G. B.; Oude Essink, G. H. P.; Stuyfzand, P. J.; Bierkens, M. F. P.

    2013-11-01

    Management of coastal fresh groundwater reserves requires a thorough understanding of the present-day groundwater salinity distribution and its possible future development. However, coastal groundwater often still reflects a complex history of marine transgressions and regressions, and is only rarely in equilibrium with current boundary conditions. In addition, the distribution of groundwater salinity is virtually impossible to characterize satisfactorily, complicating efforts to model and predict coastal groundwater flow. A way forward may be to account for the historical development of groundwater salinity when modeling present-day coastal groundwater flow. In this paper, we construct a palaeo-hydrogeological model to simulate the evolution of groundwater salinity in the coastal area of the Netherlands throughout the Holocene. While intended as a perceptual tool, confidence in our model results is warranted by a good correspondence with a hydrochemical characterization of groundwater origin. Model results attest to the impact of groundwater density differences on coastal groundwater flow on millennial timescales and highlight their importance in shaping today's groundwater salinity distribution. Not once reaching steady-state throughout the Holocene, our results demonstrate the long-term dynamics of salinity in coastal aquifers. This stresses the importance of accounting for the historical evolution of coastal groundwater salinity when modeling present-day coastal groundwater flow, or when predicting impacts of e.g. sea level rise on coastal aquifers. Of more local importance, our findings suggest a more significant role of pre-Holocene groundwater in the present-day groundwater salinity distribution in the Netherlands than previously recognized. The implications of our results extend beyond understanding the present-day distribution of salinity, as the proven complex history of coastal groundwater also holds important clues for understanding and predicting the distribution of other societally relevant groundwater constituents.

  11. 45 CFR 1340.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... day care, group day care, and center-based day care; and, at State option, any other settings in which... each of the several States, the District of Columbia, the Commonwealth of Puerto Rico, the Virgin...

  12. Carnosine reverses the aging-induced down regulation of brain regional serotonergic system.

    PubMed

    Banerjee, Soumyabrata; Ghosh, Tushar K; Poddar, Mrinal K

    2015-12-01

    The purpose of the present investigation was to study the role of carnosine, an endogenous dipeptide biomolecule, on brain regional (cerebral cortex, hippocampus, hypothalamus and pons-medulla) serotonergic system during aging. Results showed an aging-induced brain region specific significant (a) increase in Trp (except cerebral cortex) and their 5-HIAA steady state level with an increase in their 5-HIAA accumulation and declination, (b) decrease in their both 5-HT steady state level and 5-HT accumulation (except cerebral cortex). A significant decrease in brain regional 5-HT/Trp ratio (except cerebral cortex) and increase in 5-HIAA/5-HT ratio were also observed during aging. Carnosine at lower dosages (0.5-1.0μg/Kg/day, i.t. for 21 consecutive days) didn't produce any significant response in any of the brain regions, but higher dosages (2.0-2.5μg/Kg/day, i.t. for 21 consecutive days) showed a significant response on those aging-induced brain regional serotonergic parameters. The treatment with carnosine (2.0μg/Kg/day, i.t. for 21 consecutive days), attenuated these brain regional aging-induced serotonergic parameters and restored towards their basal levels that observed in 4 months young control rats. These results suggest that carnosine attenuates and restores the aging-induced brain regional down regulation of serotonergic system towards that observed in young rats' brain regions. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  13. The Relation of El Nino Southern Oscillation to Winter Tornado Outbreaks

    NASA Astrophysics Data System (ADS)

    Robinson Cook, A. D.; Schaefer, J. T.

    2007-12-01

    Winter tornado activity (January, February, and March) between 1950 and 2003 was analyzed to determine the possible effect of seasonally averaged sea surface temperatures in the equatorial Pacific Ocean, the ENSO phase, on the location and strength of tornado outbreaks in the United States. Tornado activity was gauged through analyses of tornadoes occurring on tornado days (a calendar day featuring 6 or more tornadoes within the contiguous United States) and strong and violent tornado days (a calendar day featuring 5 or more tornadoes rated F-2 and greater within the contiguous United States). The tornado days were then stratified according to warm (37 tornado days, 14 violent days), cold (51 tornado days, 28 violent days), and neutral (74 tornado days, 44 violent days) winter ENSO phase. It is seen that during winter periods of neutral tropical Pacific sea surface temperatures, there is a tendency for United States tornado outbreaks to be stronger and more frequent than they are during winter periods of anomalously warm tropical Pacific sea surface temperatures (El Nino). During winter periods with anomalously cool Pacific sea surface temperatures (La Nina), the frequency and strength of United States tornado activity lies between that of the neutral and El Nino phase. ENSO related shifts in the preferred location of tornado activity are also observed. Historically, during the neutral phase, tornado outbreaks typically occurred from central Oklahoma and Kansas eastward through the Carolinas. During cold phases, tornado outbreaks have typically occurred in a zone stretching from southeastern Texas northeastward into Illinois, Indiana, and Michigan. During anomalously warm phases activity was mainly limited to the Gulf Coast States including central Florida. The data are statistically and synoptically analyzed to show that they are not only statistically significant, but also meteorologically reasonable.

  14. 76 FR 30497 - Armed Forces Day, 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ... Forces Day, 2011 By the President of the United States of America A Proclamation The Armed Forces of the... its people. From our earliest days as a fledgling republic, the United States has relied on the.... On Armed Forces Day, let us salute the Soldiers, Sailors, Airmen, Marines, and Coast Guardsmen who...

  15. 76 FR 63531 - German-American Day, 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ...-American Day, 2011 By the President of the United States of America A Proclamation As a Nation of... observe German-American Day, we celebrate how far we have come together and remember the lasting legacy... States, do hereby proclaim October 6, 2011, as German-American Day. I encourage all Americans to learn...

  16. 77 FR 55103 - Labor Day, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... Day, 2012 By the President of the United States of America A Proclamation Through times of prosperity... the unshakable foundation of American innovation and economic growth. On Labor Day, we celebrate their... the laws of the United States, do hereby proclaim September 3, 2012, as Labor Day. I call upon all...

  17. 77 FR 65459 - United Nations Day, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-29

    ... United Nations Day, 2012 By the President of the United States of America A Proclamation Sixty-seven... United Nations Day by celebrating the founding ideals laid down in its Charter and reaffirming the... proclaim October 24, 2012, as United Nations Day. I urge the Governors of the 50 States, and the officials...

  18. 77 FR 2907 - Religious Freedom Day, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-20

    ... Religious Freedom Day, 2012 By the President of the United States of America A Proclamation For nearly four.... On Religious Freedom Day, we celebrate this historic milestone, reflect upon the Statute's... the laws of the United States, do hereby proclaim January 16, 2012, as Religious Freedom Day. I call...

  19. Khoa Trinh Huan Luyen Giu Tre Ban Ngay Tai Gia (Family Day Care Training Curriculum--Vietnamese).

    ERIC Educational Resources Information Center

    Nakatsu, Gail

    California's Family Day Care Training Program was designed to recruit and train, in 7 weeks, Lao, Vietnamese, and Chinese refugees to establish their own state-licensed, family day care homes. Topics in the program's curriculum include an introduction to family day care, state licenses and licensing requirements for family day care, licensing…

  20. Physiology of the invasive apple snail Pomacea maculata: tolerance to low temperatures

    USGS Publications Warehouse

    Deaton, Lewis E.; Schmidt, William; Leblanc, Brody; Carter, Jacoby; Mueck, Kristy; Merino, Sergio

    2016-01-01

    Apple snails of the genus Pomacea native to South America have invaded and become established in Europe, Asia, and the United States. Both the channeled apple snail Pomacea canaliculata and the island apple snail Pomacea maculata have been reported in the United States. The two species are difficult to distinguish using morphological characters, leading to uncertainty about the identity of the animals from populations in the United States. Because the snails are subtropical, their tolerance of low temperatures is a critical factor in limiting the spread of the animals from present localities along the coast of the Gulf of Mexico to more northern areas. The tolerance of P. maculata collected in Louisiana to temperatures as low as 0°C was examined. There was no mortality among animals maintained in water at temperatures of 20°C or 15°C for 10 days. Survival of animals during a 10-day exposure to water at temperatures 10°C and 5°C was 50%. The LD50 for a 10-day exposure was 7°C. Snails did not survive more than 5 days in liquid water at 0°C. Ammonia excretion by animals in temperatures of 20°C and 15°C was comparable to values reported for freshwater gastropods; at very low temperatures, excretion of ammonia was decreased. There was no difference in the mean values of the osmolality of the hemolymph of animals exposed to 20°C, 15°C and 10°C for 10 days. Sequencing of mitochondrial cytochrome oxidase 1 identified the animals in the Louisiana population used in this study as P. maculata.

  1. 38 CFR 52.10 - Per diem based on recognition and certification.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... VETERANS AFFAIRS (CONTINUED) PER DIEM FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Obtaining Per Diem for Adult Day Health Care in State Homes § 52.10 Per diem based on recognition and certification. VA will pay per diem to a State for providing adult day health care to eligible veterans in a...

  2. 38 CFR 52.10 - Per diem based on recognition and certification.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... VETERANS AFFAIRS (CONTINUED) PER DIEM FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Obtaining Per Diem for Adult Day Health Care in State Homes § 52.10 Per diem based on recognition and certification. VA will pay per diem to a State for providing adult day health care to eligible veterans in a...

  3. 38 CFR 52.10 - Per diem based on recognition and certification.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... VETERANS AFFAIRS (CONTINUED) PER DIEM FOR ADULT DAY HEALTH CARE OF VETERANS IN STATE HOMES Obtaining Per Diem for Adult Day Health Care in State Homes § 52.10 Per diem based on recognition and certification. VA will pay per diem to a State for providing adult day health care to eligible veterans in a...

  4. 31 CFR 205.12 - What funding techniques may be used?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... that the State pays out each day. The projected amount paid out each day is determined by applying a clearance pattern to the total amount the State will disburse. (3) Average clearance means that a Federal Program Agency, on the dollar-weighted average day of clearance of a disbursement, transfers to a State a...

  5. 2011 Astronomy Day at McDonald Observatory

    NASA Astrophysics Data System (ADS)

    Preston, Sandra; Hemeway, M.; Wetzel, M.

    2012-01-01

    Our philosophy is that everyday is Astronomy Day because the McDonald Observatory's Frank N. Bash Visitors Center is open 362 days a year. So, how did we create a special celebration for the "Astronomy Day” declared by the Astronomical League? During September 26-29 we conducted 20 videoconferences and served 12,559 students with "Astronomy Day” programming. Connect2Texas provides bridging for a network of Texas-based museums and cultural, historical, and scientific organizations that offer educational content to schools throughout the state via videoconferencing. Connect2Texas connected McDonald Observatory to 334 schools; most of these schools were in Texas, but schools in a dozen other states also participated. While most schools had a "view-only" connection, at least 20 of the schools had interactive connections, whereby the students could ask questions of the presenter. Connect2Texas also collects evaluation information from the participating schools that we will use to produce a report for our funders and make modifications to future programs as need be. The videoconferences were offered free of charge. The theme for the 2011 Astronomy Day program was the Year of the Solar System, which aligns with NASA's theme for 2011 and 2012. By aligning with this NASA theme, we could leverage NASA artwork and materials to both advertise and enrich the learning experience. Videoconference materials also included pre- and post-videoconference assessment sheets, an inquiry based activity, and pre- and post-videoconference activities, all of which were made available online. One of the lessons learned from past Astronomy Day videoconferences is that the days the Astronomical League declares as "Astronomy Day” are not always good days for Texas schools to participate. So, we choose an Astronomy Day that meets the needs of Texas schools and our schedule - so any day can be Astronomy Day. 2011 Astronomy Day was made possible by The Meyer-Levy Charitable Trust.

  6. State Patty’s Day: College Student Drinking and Local Crime Increased on a Student-constructed Holiday

    PubMed Central

    Lefkowitz, Eva S.; Patrick, Megan E.; Morgan, Nicole R.; Bezemer, Denille H.; Vasilenko, Sara A.

    2012-01-01

    College student alcohol consumption is a major concern, and is known to increase during the celebration of special events. This study examined a student-constructed holiday, State Patty’s Day, at a university with a dominant drinking culture using three sources of data – coded data from Facebook groups, daily web surveys from first-year students (N= 227, 51% male, age 18 to 20; 27.3% Hispanic/Latino; of non-Hispanic/Latino, 26.9% of sample European American/White, 19.4% Asian American/Hawaiian/Pacific Islander, 15.9% African American/Black, 10.6% more than one race), and criminal offense data from police records. Results indicated that messages about State Patty’s Day on Facebook focused on drinking and social aspects of the holiday, such as the social context of drinking, a sense of belonging to a larger community, and the social norms of drinking. These messages were rarely about consequences and rarely negative. On State Patty’s Day, 51% of students consumed alcohol, compared to 29% across other sampled weekend days. Students consumed more drinks (M = 8.2 [SD = 5.3] drinks per State Patty’s Day drinker) and were more likely to engage in heavy drinking on State Patty’s Day, after controlling for gender, drinking motives, and weekend, demonstrating the event-specific spike in heavy drinking associated with this holiday. The impact of this student-constructed holiday went beyond individual drinking behavior; alcohol-specific and other crime also peaked on State Patty’s Day and the day after. Event-specific prevention strategies may be particularly important in addressing these spontaneous, quickly-constructed, and dynamic events. PMID:22685369

  7. Medical serials control systems by computer--a state of the art review.

    PubMed

    Brodman, E; Johnson, M F

    1976-01-01

    A review of the problems encountered in serials control systems is followed by a description of some of the present-day attempts to solve these problems. Specific networks are described, notably PHILSOM (developed at Washington University School of Medicine Library), the UCLA Biomedical Library's system, and OCLC in Columbus, Ohio. Finally, the role of minicomputers in present and future developments is discussed, and some cautious guesses are made on future directions in the field.

  8. Quantum communication and information processing

    NASA Astrophysics Data System (ADS)

    Beals, Travis Roland

    Quantum computers enable dramatically more efficient algorithms for solving certain classes of computational problems, but, in doing so, they create new problems. In particular, Shor's Algorithm allows for efficient cryptanalysis of many public-key cryptosystems. As public key cryptography is a critical component of present-day electronic commerce, it is crucial that a working, secure replacement be found. Quantum key distribution (QKD), first developed by C.H. Bennett and G. Brassard, offers a partial solution, but many challenges remain, both in terms of hardware limitations and in designing cryptographic protocols for a viable large-scale quantum communication infrastructure. In Part I, I investigate optical lattice-based approaches to quantum information processing. I look at details of a proposal for an optical lattice-based quantum computer, which could potentially be used for both quantum communications and for more sophisticated quantum information processing. In Part III, I propose a method for converting and storing photonic quantum bits in the internal state of periodically-spaced neutral atoms by generating and manipulating a photonic band gap and associated defect states. In Part II, I present a cryptographic protocol which allows for the extension of present-day QKD networks over much longer distances without the development of new hardware. I also present a second, related protocol which effectively solves the authentication problem faced by a large QKD network, thus making QKD a viable, information-theoretic secure replacement for public key cryptosystems.

  9. A daily diary study of self-compassion, body image, and eating behavior in female college students.

    PubMed

    Kelly, Allison C; Stephen, Elizabeth

    2016-06-01

    Although self-compassion is associated with healthier body image and eating behavior, these findings have generally emerged at the between-persons level only. The present study investigated the unique contributions of within-person variability in self-compassion, and between-persons differences in self-compassion, to body image and eating behavior. Over seven days, 92 female college students completed nightly measures of self-compassion, self-esteem, dietary restraint, intuitive eating, body appreciation, body satisfaction, and state body image. Multilevel modeling revealed that within-persons, day-to-day fluctuations in self-compassion contributed to day-to-day fluctuations in body image and eating. Between-persons, participants' average levels of self-compassion across days contributed to their average levels of body image and eating over the week. Results generally held when controlling for within- and between-persons self-esteem. Evidently, the eating and body image benefits of self-compassion may come not only from being a generally self-compassionate person, but also from treating oneself more self-compassionately than usual on a given day. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. New Mexico climate manual: solar and weather data. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Morris, W.S.; Haggard, K.W

    This manual contains extensive solar and weather data for the state of New Mexico in tabular, map, and graphic formats. It is particularly relevant to design of energy efficient buildings and renewable energy systems, but is also broad enough to provide useful information to many other disciplines. Maps of the state show monthly values of insolation for horizontal, south-facing latitude-tilted and vertical surfaces, as well as mean temperatures. Climatic summaries given for 63 sites include monthly temperature and precipitation data as well as heating/cooling degree-days and design temperatures. For nine locations (Albuquerque, Clayton, Farmington, Los Alamos, Roswell, T or C,more » Tucumcari, Zuni, and El Paso, Texas) most of the following comprehensive data sets are also presented: design temperatures with mean coincident wet bulb and wind values; HDD/CDD values to 12 base temperatures; day/night wind data; typical and clear-day values of incident and transmitted solar radiation for 97 orientations and tilts; and temperature distribution data in 2/sup 0/F bins for six daily time periods. Extensive explanatory text with referencing to the data is provided.« less

  11. Spectral phasor analysis of LAURDAN fluorescence in live A549 lung cells to study the hydration and time evolution of intracellular lamellar body-like structures.

    PubMed

    Malacrida, Leonel; Astrada, Soledad; Briva, Arturo; Bollati-Fogolín, Mariela; Gratton, Enrico; Bagatolli, Luis A

    2016-11-01

    Using LAURDAN spectral imaging and spectral phasor analysis we concurrently studied the growth and hydration state of subcellular organelles (lamellar body-like, LB-like) from live A549 lung cancer cells at different post-confluence days. Our results reveal a time dependent two-step process governing the size and hydration of these intracellular LB-like structures. Specifically, a first step (days 1 to 7) is characterized by an increase in their size, followed by a second one (days 7 to 14) where the organelles display a decrease in their global hydration properties. Interestingly, our results also show that their hydration properties significantly differ from those observed in well-characterized artificial lamellar model membranes, challenging the notion that a pure lamellar membrane organization is present in these organelles at intracellular conditions. Finally, these LB-like structures show a significant increase in their hydration state upon secretion, suggesting a relevant role of entropy during this process. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. [Particular evolution of the thyroid state in Grave's disease: two cases].

    PubMed

    Cherif, Lotfi; Ben Abdallah, Néjib; Khairi, Karima; Hadj Ali, Inçaf; Turki, Sami; Ben Maïz, Hédi

    2003-09-01

    We report two cases of Grave's disease (GD) caracterized by the succession of hypothyroid and hyperthyroid states. Case 1: A 32 years old woman, has presented initially a typical GD with hyperthyroidism. Grave's ophtalmopathy and homogenous goiter. Four months later, she presented a spontaneous hypothyroidism necessiting treatment with thyroxine and a severe myasthenia gravis. More later (6 months), she experienced symptoms of hyperthyroidism after thymectomy. The level of anti-thyrotropin-receptor antibodies (TSab) was very high (141 UI/I, NV < 10). Case 2: A 29 years old woman has been treated by thyroxine (150 microg/day) for a primary hypothyroidism. Ten months later, she presented symptoms of hyperthyroidism even after stoppage of thyroxine. TSH value was decreased (TSH < 0.05 microU/ml) and FT4 level was raised (FT4 = 25.5 pmol/l). The thyroid antibodies were positive. We discuss, after review of the litterature, the physiopathological mecanisms of these changes in the thyroid state, particularly the role of the blocking and stimulating anti-thyrotropin-receptor antibodies.

  13. Inferences About the Early Moon From Gravity and Topography

    NASA Technical Reports Server (NTRS)

    Smith, D. E.; Zuber, M. T.

    1998-01-01

    Recent spacecraft missions to the Moon have significantly improved our knowledge of the lunar gravity and topography fields, and have raised some new and old questions about the early lunar history. It has frequently been assumed that the shape of the Moon today reflects an earlier equilibrium state and that the Moon has retained some internal strength. Recent analysis indicating a superisostatic state of some lunar basins lends support to this hypothesis. On its simplest level, the present shape of the Moon is slightly flattened by 2.2 +/- 0.2 km while its gravity field, represented by an equipotential surface, is flattened only about 0.5 km. The hydrostatic component to the flattening arising from the Moon's present day rotation contributes only 7 m. This difference between the topographic shape of the MOon and the shape of its gravitational equipotential has frequently been explained as the "memory" of an earlier moon that was rotating faster and had a correspondingly larger hydrostatic flattening. To obtain this amount of hydrostatic flattening from rotation alone, and accounting for the contribution of the present-day gravity field, the Moon's rotation rate would need to be about 15x greater than at present, leading ot a period of < 2 days. Maintaining its synchronous rotation with Earth would require a radius for the Moon's orbit of approximately 9 Earth Radii. Unfortunately, our confidence in the observed lunar flattening is not as great as we would like. The uncertainty of .02 km may not properly reflect the limitations of the Clementine dataset, which did not sample poleward of latitudes 81 N and 79 S. Also, the large variation of topography +/- 8 km seen on the MOon dwarfs our estimate fo the flattening. Further the lunar south pole is on the edge of, or possibly inside the massive deep, South Pole-Aitken Basin. Thus, polar radii could be underestimated. This would yield a smaller flattening, which would imply a greater lunar rotation period and orbital radius. However, Basin compensation states and analyses of support and relaxation of topography at long wavelengths point to a lunar shape that has retained a flattening from an earlier faster rotation period.

  14. PREFACE: 2nd International Conference and Young Scientist School ''Magnetic resonance imaging in biomedical research''

    NASA Astrophysics Data System (ADS)

    Naumova, A. V.; Khodanovich, M. Y.; Yarnykh, V. L.

    2016-02-01

    The Second International Conference and Young Scientist School ''Magnetic resonance imaging in biomedical research'' was held on the campus of the National Research Tomsk State University (Tomsk, Russia) on September 7-9, 2015. The conference was focused on magnetic resonance imaging (MRI) applications for biomedical research. The main goal was to bring together basic scientists, clinical researchers and developers of new MRI techniques to bridge the gap between clinical/research needs and advanced technological solutions. The conference fostered research and development in basic and clinical MR science and its application to health care. It also had an educational purpose to promote understanding of cutting-edge MR developments. The conference provided an opportunity for researchers and clinicians to present their recent theoretical developments, practical applications, and to discuss unsolved problems. The program of the conference was divided into three main topics. First day of the conference was devoted to educational lectures on the fundamentals of MRI physics and image acquisition/reconstruction techniques, including recent developments in quantitative MRI. The second day was focused on developments and applications of new contrast agents. Multinuclear and spectroscopic acquisitions as well as functional MRI were presented during the third day of the conference. We would like to highlight the main developments presented at the conference and introduce the prominent speakers. The keynote speaker of the conference Dr. Vasily Yarnykh (University of Washington, Seattle, USA) presented a recently developed MRI method, macromolecular proton fraction (MPF) mapping, as a unique tool for modifying image contrast and a unique tool for quantification of the myelin content in neural tissues. Professor Yury Pirogov (Lomonosov Moscow State University) described development of new fluorocarbon compounds and applications for biomedicine. Drs. Julia Velikina and Alexey Samsonov (University of Wisconsin-Madison, USA) demonstrated new image reconstruction methods for accelerated quantitative parameter mapping and magnetic resonance angiography. Finally, we would like to thank the scientific committee, the local organizing committee and the National Research Tomsk State University for giving an opportunity to share scientific ideas and new developments at the conference and the Russian Science Foundation (project № 14-45-00040) for financial support.

  15. Hyperammonemic coma after craniotomy: Hepatic encephalopathy from upper gastrointestinal hemorrhage or valproate side effect?: Case report and literature review.

    PubMed

    Guo, Xiaopeng; Wei, Junji; Gao, Lu; Xing, Bing; Xu, Zhiqin

    2017-04-01

    Postoperative coma is not uncommon in patients after craniotomy. It generally presents as mental state changes and is usually caused by intracranial hematoma, brain edema, or swelling. Hyperammonemia can also result in postoperative coma; however, it is rarely recognized as a potential cause in coma patients. Hyperammonemic coma is determined through a complicated differential diagnosis, and although it can also be induced as a side effect of valproate (VPA), this cause is frequently unrecognized or confused with upper gastrointestinal hemorrhage (UGH)-induced hepatic encephalopathy. We herein present a case of valproate-induced hyperammonemic encephalopathy (VHE) to illustrate the rarity of such cases and emphasize the importance of correct diagnosis and proper treatment. A 61-year-old woman with meningioma was admitted into our hospital. Radical resection of the tumor was performed, and the patient recovered well as expected. After administration of valproate for 7 days, the patient was suddenly found in a deep coma, and her mental state deteriorated rapidly. The diagnoses of hepatic encephalopathy was confirmed. However, whether it origins from upper gastrointestinal hemorrhage or valproate side effect is uncertain. The patient's condition fluctuated without improvement during the subsequent 3 days under the treatment of reducing ammonia. With the discontinuation of valproate treatment, the patient regained complete consciousness within 48 hours, and her blood ammonia decreased to the normal range within 4 days. VHE is a rare but serious complication in patients after craniotomy and is diagnosed by mental state changes and elevated blood ammonia. Thus, the regular perioperative administration of VPA, which is frequently neglected as a cause of VHE, should be emphasized. In addition, excluding UGH prior to providing a diagnosis and immediately discontinuing VPA administration are recommended.

  16. Heart failure rehospitalization of the Medicare FFS patient: a state-level analysis exploring 30-day readmission factors.

    PubMed

    Schmeida, Mary; Savrin, Ronald A

    2012-01-01

    Heart failure readmission among the elderly is frequent and costly to both the patient and the Medicare trust fund. In this study, the authors explore the factors that are associated with states having heart failure readmission rates that are higher than the U.S. national rate. Acute inpatient hospital settings. 50 state-level data and multivariate regression analysis is used. The dependent variable Heart Failure 30-day Readmission Worse than U.S. Rate is based on adult Medicare Fee-for-Service patients hospitalized with a primary discharge diagnosis of heart failure and for which a subsequent inpatient readmission occurred within 30 days of their last discharge. One key variable found--states with a higher resident population speaking a primary language other than English at home--that is significantly associated with a decrease in probability in states ranking "worse" on heart failure 30-day readmission. Whereas, states with a higher median income, more total days of care per 1,000 Medicare enrollees, and a greater percentage of Medicare enrollees with prescription drug coverage have a greater probability for heart failure 30-day readmission to be "worse" than the U.S. national rate. Case management interventions targeting health literacy may be more effective than other factors to improve state-level hospital status on heart failure 30-day readmission. Factors such as total days of care per 1,000 Medicare enrollees and improving patient access to postdischarge medication(s) may not be as important as literacy. Interventions aimed to prevent disparities should consider higher income population groups as vulnerable for readmission.

  17. Co-ingestion of amatoxins and isoxazoles-containing mushrooms and successful treatment: A case report.

    PubMed

    Garcia, Juliana; Costa, Vera M; Costa, Ana Elisa; Andrade, Sérgio; Carneiro, Ana Cristina; Conceição, Filipe; Paiva, José Artur; de Pinho, Paula Guedes; Baptista, Paula; de Lourdes Bastos, Maria; Carvalho, Félix

    2015-09-01

    Mushroom poisonings occur when ingestion of wild mushrooms containing toxins takes place, placing the consumers at life-threatening risk. In the present case report, an unusual multiple poisoning with isoxazoles- and amatoxins-containing mushrooms in a context of altered mental state and poorly controlled hypertension is presented. A 68-year-old female was presented to São João hospital (Portugal) with complaints of extreme dizziness, hallucinations, vertigo and imbalance, 3 h after consuming a stew of wild mushrooms. The first observations revealed altered mental state and elevated blood pressure. The examination of cooked mushroom fragments allowed a preliminary identification of Amanita pantherina. Gas chromatography-mass spectrometry (GC-MS) showed the presence of muscimol in urine. Moreover, through high-performance liquid chromatography-ultraviolet detection (HPLC-UV) analysis of the gastric juice, the presence of α-amanitin was found, showing that amatoxins-containing mushrooms were also included in the stew. After 4 days of supportive treatment, activated charcoal, silybin and N-acetylcysteine, the patient recovered being discharged 10 days post-ingestion with no organ complications. The prompt and appropriate therapy protocol for life-threatening amatoxins toxicity probably saved the patient's life as oral absorption was decreased and also supportive care was immediately started. Copyright © 2015 Elsevier Ltd. All rights reserved.

  18. Diagnosis and management of Transposition of great arteries within a pediatric cardiology network with the aid of telemedicine: A case report from Brazil.

    PubMed

    Galdino, Millena M; Hazin, Sheila Mv; de Araújo, Juliana Ss; Regis, Cláudio T; Rodrigues, Klecida N; Mourato, Felipe A; Mattos, Sandra da Silva

    2016-04-01

    We present a case of a newborn from a remote, underserved area in the inland of Paraíba, a state from Northeast Brazil. She presented with clinical cyanosis at birth. With the aid of telemedicine, a neonatologist under online cardiology supervision performed a screening echocardiogram. The session established the diagnosis of simple transposition of the great vessels in the baby's first few hours of life. During the same telemedicine session, the necessary arrangements for transferal to a larger maternity center took place. The baby was maintained stable on prostaglandins and was subsequently transferred to a tertiary cardiac center in the neighboring State, Pernambuco. She underwent anatomical correction at day 10, presented no surgical or postoperative complications, and was discharged home at the age of 21 days. She is now over three years old and continues her follow-up care mostly at her hometown, with local pediatricians under online supervision by a cardiologist in a virtual outpatient clinic. The establishment of a Pediatric Cardiology Network, with the aid of telemedicine, can produce a major impact on the access to specialized health care for poor regions of developing countries. © The Author(s) 2015.

  19. Diagnosis, symptoms, frequency and mortality of 260 patients with urea cycle disorders from a 21-year, multicentre study of acute hyperammonaemic episodes.

    PubMed

    Summar, Marshall L; Dobbelaere, Dries; Brusilow, Saul; Lee, Brendan

    2008-10-01

    A large longitudinal interventional study of patients with a urea cycle disorder (UCD) in hyperammonaemic crisis was undertaken to amass a significant body of data on their presenting symptoms and survival. Between 1982 and 2003, as part of the FDA approval process, data were collected on patients receiving an intravenous combination of nitrogen scavenging drugs (Ammonul sodium phenylacetate and sodium benzoate (10%, 10%)) for the treatment of hyperammonaemic crises caused by urea cycle disorders. A final diagnosis of a UCD was made for 260 patients, representing 975 episodes of hospitalization. Only 34% of these patients presented within the first 30 days of life and had a mortality rate of 32%. The most common presenting symptoms were neurological (80%), or gastrointestinal (33%). This cohort is the largest collection of patients reported for these diseases and the first large cohort in the United States. Surprisingly, the majority (66%) of patients with heritable causes of hyperammonaemia present beyond the neonatal period (>30 days). Patients with late-onset presenting disorders exhibited prolonged survival compared to the neonatal-presenting group.

  20. 75 FR 62453 - German-American Day, 2010

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ...-American Day, 2010 By the President of the United States of America A Proclamation The American story has... national life. On German-American Day, we pay tribute to the role this community has played in shaping... the laws of the United States, do hereby proclaim October 6, 2010, as German-American Day. I encourage...

  1. Maryland Day Care Voucher System.

    ERIC Educational Resources Information Center

    Hildebrand, Joan M.

    This manual was written to assist States and other governmental units wishing to replicate the Maryland Day Care Voucher Program, a system of providing child care subsidies to eligible families. Chapter I provides brief histories of day care in Maryland and that State's grant to demonstrate the viability of a day care voucher system. Chapter II…

  2. Seventh/Eighth Grade Social Studies. United States and New York State History. A Calendar of Lessons.

    ERIC Educational Resources Information Center

    Bromberg, Lloyd; And Others

    This calendar of lessons conforms to the New York State syllabus for grades 7-8, United States and New York History, which was officially implemented throughout the state in September 1987. It is a guide to the objectives of the state social studies program, not a prescription for day-to-day lesson plans. United States and New York State History…

  3. 77 FR 64386 - Agency Information Collection Activities (Per Diem for Nursing Home Care of Veterans in State...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... Activities (Per Diem for Nursing Home Care of Veterans in State Homes; Per Diem for Adult Day Care of.... Abstract: VA pays per diem to State homes providing nursing home and adult day health services care to Veterans. VA requires facilities providing nursing home and adult day health care to furnish an application...

  4. Forests and floods in the eastern United States

    Treesearch

    Howard W. Lull; Kenneth G. Reinhart; Kenneth G. Reinhart

    1972-01-01

    Our purpose is to examine in detail the influence of the present-day forest on flood runoff and sedimentation. Forests and flood discharge wiI1 be our dominant concern; sedimentation by and large is a byproduct of their interaction. This paper was prepared for foresters, conservationists, and others acquainted with the processes and terminology of the hydrologic cycle...

  5. 77 FR 61782 - Notice of Inventory Completion: Washington State Parks and Recreation Commission, Olympia, WA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-11

    ... completed an inventory of human remains, in consultation with the appropriate Indian tribes, and has determined that there is a cultural affiliation between the human remains and a present-day Indian tribe. Representatives of any Indian tribe that believes itself to be culturally affiliated with the human remains may...

  6. Past is prologue: a synthesis of state forest management activities and hardwood ecosystem experiment pre-treatment results

    Treesearch

    G. Scott Haulton

    2013-01-01

    Disturbance plays an important role in forest development processes. Present-day forest condition can be viewed as the cumulative result of various historical disturbance events; therefore, an understanding of disturbance history is important when describing overall forest condition. Pre-treatment studies of the Hardwood Ecosystem Experiment (HEE) have described...

  7. Effective Special Teacher Characteristics: Perceptions of Preschool Special Educators in Greece

    ERIC Educational Resources Information Center

    Soulis, Spiridon-Georgios

    2009-01-01

    The aim of the present study was to evaluate six characteristics of effective special pre-school teachers, similar to those used in the relevant literature. The study participants were all special teachers (n = 226), serving in Greek state and community pre-primary educational institutions (i.e. kindergartens and day nurseries) for children with…

  8. The Rainbow Connection: How Music Classrooms Create Safe Spaces for Sexual-Minority Young People

    ERIC Educational Resources Information Center

    Southerland, William

    2018-01-01

    LGBTQ students in many parts of the United States often experience hostility on the part of other students, teachers, and administrators. This article reviews current terminology, examines present-day attitudes and recent literature, and offers suggestions to educators who want to create safe spaces for all students in their classrooms.

  9. Pedagogical Sustainability of a Rural School and Its Relationship with Community

    ERIC Educational Resources Information Center

    Kinash, Shelley; Hoffman, Michelle

    2009-01-01

    This article presents and analyses a single pedagogic case of a small, rural primary state school in Queensland, Australia. The researchers spent one day per week for nineteen weeks serving the role of visiting teachers to the school. The goal of the research was to inquire into the pedagogical sustainability of this rural school and its…

  10. Why sustain oak forests?

    Treesearch

    David Wm. Smith

    2006-01-01

    A brief overview and some personal thoughts are offered that deal with the implications of our social and political systems on the long-term sustainability of our forest resources. The connection of the most recent climatic events, in a geologic-time context, to the development of present day oak dominated forests of the Eastern United States is discussed. The impacts...

  11. Natural Justice: Its Definition and Application to the Termination of School System Employees.

    ERIC Educational Resources Information Center

    Anderson, Judith C.; Anderson, James E.

    The Canadian concept of "natural justice" is equivalent to "due process" in the United States. This paper traces the evolution of natural justice from English common law to its function in present day Canadian law. The extension of natural justice to school board employees is discussed. The paper points out that although in the…

  12. An Intercultural Seminar for Foreign and U.S. University Students.

    ERIC Educational Resources Information Center

    Colorado State Univ., Ft. Collins.

    Presented is a discussion of an intercultural orientation seminar for foreign and U.S. university students at Colorado State University. This 1-day retreat is held each semester at a lodge in the Rocky Mountains. It is designed to bring together the students and community people to experience an international environment where the goal is to…

  13. Stimulating Physical Development of Mentally Retarded Children. Mental Retardation Training Program Technical Report Series 70-3.

    ERIC Educational Resources Information Center

    Stein, Julian U.; And Others

    Four papers presented at an all-day workshop at Ohio State University focus on stimulating the physical development of mentally retarded children. Noted in the introduction is importance of cooperation between university training programs and facilities serving the mentally handicapped. Julian Stein discusses the physical and motor development of…

  14. Vulnerabilities of Southwestern U.S. rangeland-based animal agriculture to climate change

    USDA-ARS?s Scientific Manuscript database

    The Southwestern US is a 5-state region that has supported animal agriculture since the late 16th Century when European settlers crossed the Rio Grande into present day west Texas and southern New Mexico with herds of cattle, sheep, goats and horses. For the past 400 years the rangeland livestock i...

  15. The Federalist Era. SSEC American History Series.

    ERIC Educational Resources Information Center

    Ladenburg, Thomas

    This unit on the Federalist era of U.S. history examines some of the issues that have endured from the earliest days of the nation to the present: free speech, the right to rebel, foreign policy, the balance of federal and state authority, and the relative importance of various constituencies. Student understanding of such issues develops through…

  16. Report from the International Permafrost Association: state of permafrost in the first decade of the 21st century

    Treesearch

    J. Brown; V.E. Romanovsky

    2008-01-01

    Recent assessments have considered present-day and future responses of permafrost terrain to climate change; included are the Intergovernmental Panel on Climate Change (IPCC) , Arctic Climate Impact Assessment (ACIA) and United Nations Environment Programme assessments (Romanovsky et al., 2007), the on-going National Oceanic and Atmospheric Administration (NOAA) annual...

  17. Modeling a Day in the Life of a Diabetic

    ERIC Educational Resources Information Center

    Brod, Ryan; Gomber, John; Mendoza, Jurelle; Roginski, Jonathan; Smith, Tyler

    2010-01-01

    The material presented here was used for a semester-long capstone project for a first semester freshman course entitled Mathematical Modeling and Introduction to Calculus. The goals for the students in this work were twofold: first, enable the students to gain insight into an actual problem that affects millions of people in the United States and…

  18. A Short History of Structural Linguistics.

    ERIC Educational Resources Information Center

    Matthews, Peter

    This book is a concise history of structural linguistics, charting its development from the 1870s to the present day. It explains what structuralism was and why its ideas are still central today. For structuralists, a language is a self-contained and tightly organized system whose history is of changes from one state of the system to another. This…

  19. Peut-on Eduquer des Enfants Sans un Projet de Societe?

    ERIC Educational Resources Information Center

    Caouette, Charles E.

    1988-01-01

    Discusses the responsibility of educators of young children to make a commitment to the future of pre-school education. Discusses the relationship of education to present day society and to future societies. States that it is OMEP-CANADA's mandate to work with systems to find ways to prevent violence, abuse, alienation, and suicide. Text is in…

  20. South Africa/Time Running Out.

    ERIC Educational Resources Information Center

    Clark, Todd, Ed.

    1984-01-01

    Based on the book, "South Africa: Time Running Out," a report of the Study Commission on U.S. Policy Toward Southern Africa, this 10-20 day unit of study is designed to help high school students learn about the history, geography, and present situation in South Africa and its relationship to the United States. The first of four sections…

  1. Sessions and Abstracts by Day for Satellite Meeting: Comparative Physiology of Respiration with Emphasis on Avian Respiratory Control, October 11 and 12, 1981.

    ERIC Educational Resources Information Center

    Physiologist, 1981

    1981-01-01

    Provides abstracts of contributed and invited papers presented at a satellite meeting on "Comparative Physiology of Respiration," October 11 and 12, 1981, at Ohio State University, as part of the 32nd Annual Fall Meeting of the American Physiological Society. (CS)

  2. 12 CFR 390.254 - How may a subsidiary of a State savings association issue securities?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... days that the notice presents supervisory concerns or raises significant issues of law or policy, you... made available to the subsidiary; the percentage that such amount represents of the current book value of your assets on an unconsolidated basis; and the current book value of all such assets of the...

  3. 12 CFR 390.254 - How may a subsidiary of a State savings association issue securities?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... days that the notice presents supervisory concerns or raises significant issues of law or policy, you... made available to the subsidiary; the percentage that such amount represents of the current book value of your assets on an unconsolidated basis; and the current book value of all such assets of the...

  4. 12 CFR 390.254 - How may a subsidiary of a State savings association issue securities?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... days that the notice presents supervisory concerns or raises significant issues of law or policy, you... made available to the subsidiary; the percentage that such amount represents of the current book value of your assets on an unconsolidated basis; and the current book value of all such assets of the...

  5. Biomass: An Alternative Source of Energy for Eighth or Ninth Grade Science.

    ERIC Educational Resources Information Center

    Heyward, Lillie; Murff, Marye

    This teaching unit develops the possibility of using biomass as an alternative source of energy. The concept of biomass is explained and the processes associated with its conversion to energy are stated. Suggestions for development of biomass technology in different geographic areas are indicated. Lessons for 6 days are presented for use with…

  6. 77 FR 21870 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ... sites that appear to present a significant risk to public health, welfare, or the environment. Sites on... investigation has shown that the release poses no significant threat to public health or the environment and... ``Proposed Rules'' section of the Federal Register. 2. EPA has provided the State with 30 working days for...

  7. Challenges to United States Tactical Air Force Aircraft Maintenance Personnel: Past, Present and Future

    DTIC Science & Technology

    1991-09-01

    to Britain by Germany, the British ship Lusitania was sunk, 7 May 1915, by a German submarine. Included in the 1,198 passengers killed were 128...against neutral shipping. Seven months to the day the Lusitania was sunk, President Wilson asked Congress for an increase in military furds. On February 3

  8. Time-Dependent Solid State Polymorphism of a Series of Donor-Acceptor Dyads

    PubMed Central

    Peebles, Cameron; Alvey, Paul M.; Lynch, Vincent; Iverson, Brent L.

    2014-01-01

    In order to exploit the use of favorable electrostatic interactions between aromatic units in directing the assembly of donor-acceptor (D-A) dyads, the present work examines the ability of conjugated aromatic D-A dyads with symmetric side chains to exhibit solid-state polymorphism as a function of time during the solid formation process. Four such dyads were synthesized and their packing in the solid-state from either slower (10-20 days) or faster (1-2 days) evaporation from solvent was investigated using single crystal X-ray analysis and powder X-ray diffraction. Two of the dyads exhibited tail-to-tail (A-A) packing upon slower evaporation from solvent and head-to-tail (D-A) packing upon faster evaporation from solvent. A combination of single crystal analysis and XRD patterns were used to create models wherein a packing model for the other two dyads is proposed. Our findings suggest that while side chain interactions in asymmetric aromatic dyads can play an important role in enforcing segregated D-A dyad assembly, slowly evaporating symmetrically substituted aromatic dyads allows for favorable electrostatic interactions between the aromatic moieties to facilitate the organization of the dyads in the solid-state. PMID:24678269

  9. [Associations among physical condition, life hour, and dietary intake male Japanese shift workers: physical condition and lifestyle survey of male Japanese shift workers].

    PubMed

    Fukumura, Tomoe; Yoshita, Katsushi; Tabata, Masaji

    2015-01-01

    The purpose of this study was to understand the actual state of life hours (working time, sleep time, and time of meal intake) and dietary habits of male shift work employees, and to elucidate the impact of working arrangements and dietary habits on their physical condition and health problems. The subjects were 187 male employees (aged 18-64 years) working for an industrial company in Toyama prefecture. We used a self-administered questionnaire to assess dietary habit, lifestyle habits, and life hours at the time of a periodic health examination in April 2013. The subjects were grouped based on their working condition (i.e., day shift, late shift, and late-night shift) into two groups of day shift (n = 107) and shiftwork (n = 80). The proportion of time spent sleeping and feeding was determined in half hour increments, and the incidences of skipping meals (breakfast, lunch and dinner) and midnight snack intake were calculated for each working condition. We also examined the association between the frequency of eating and physical condition for each working condition. The state of life hours of the shiftwork group during the day was similar to that of the day shift group. However, the workers' state of life hours, incidences of skipping meals, and midnight snack intake varied considerably when working at the other shift times. In the shiftwork group, regardless of the working patterns, the BMI and % body fat of the group that ate more than three times a day were significantly lower than those of the group that ate less than twice a day. The results of the present study suggest that it is difficult to ensure the time and opportunity for meals for shift workers. We consider that it is necessary to prevent them skipping of meals, and to support a proper dietary intake during the night.

  10. Regulation of autonomic nervous system in space and magnetic storms.

    PubMed

    Baevsky, R M; Petrov, V M; Chernikova, A G

    1998-01-01

    Variations in the earth's magnetic field and magnetic storms are known to be a risk factor for the development of cardiovascular disorders. The main "targets" for geomagnetic perturbations are the central nervous system and the neural regulation of vascular tone and heart rate variability. This paper presents the data about effect of geomagnetic fluctuations on human body in space. As a method for research the analysis of heart rate variability was used, which allows evaluating the state of the sympathetic and parasympathetic parts of the autonomic nervous system, vasomotor center and subcortical neural centers activity. Heart rate variability data were analyzed for 30 cosmonauts at the 2nd day of space flight on transport spaceship Soyuz (32nd orbit). There were formed three groups of cosmonauts: without magnetic storm (n=9), on a day with magnetic storm (n=12) and 1-2 days after magnetic storm (n=9). The present study was the first to demonstrate a specific impact of geomagnetic perturbations on the system of autonomic circulatory control in cosmonauts during space flight. The increasing of highest nervous centers activity was shown for group with magnetic storms, which was more significant on 1-2 days after magnetic storm. The use of discriminate analysis allowed to classify indicated three groups with 88% precision. Canonical variables are suggested to be used as criterions for evaluation of specific and non-specific components of cardiovascular reactions to geomagnetic perturbations. The applied aspect of the findings from the present study should be emphasized. They show, in particular, the need to supplement the medical monitoring of cosmonauts with predictions of probable geomagnetic perturbations in view of the prevention of unfavorable states appearances if the adverse reactions to geomagnetic perturbations are added to the tension experienced by regulatory systems during various stresses situations (such as work in the open space).

  11. Tracking children's mental states while solving algebra equations.

    PubMed

    Anderson, John R; Betts, Shawn; Ferris, Jennifer L; Fincham, Jon M

    2012-11-01

    Behavioral and function magnetic resonance imagery (fMRI) data were combined to infer the mental states of students as they interacted with an intelligent tutoring system. Sixteen children interacted with a computer tutor for solving linear equations over a six-day period (days 0-5), with days 1 and 5 occurring in an fMRI scanner. Hidden Markov model algorithms combined a model of student behavior with multi-voxel imaging pattern data to predict the mental states of students. We separately assessed the algorithms' ability to predict which step in a problem-solving sequence was performed and whether the step was performed correctly. For day 1, the data patterns of other students were used to predict the mental states of a target student. These predictions were improved on day 5 by adding information about the target student's behavioral and imaging data from day 1. Successful tracking of mental states depended on using the combination of a behavioral model and multi-voxel pattern analysis, illustrating the effectiveness of an integrated approach to tracking the cognition of individuals in real time as they perform complex tasks. Copyright © 2011 Wiley Periodicals, Inc.

  12. Plant distributions in the southwestern United States; a scenario assessment of the modern-day and future distribution ranges of 166 Species

    USGS Publications Warehouse

    Thomas, Kathryn A.; Guertin, Patricia P.; Gass, Leila

    2012-01-01

    The authors developed spatial models of the predicted modern-day suitable habitat (SH) of 166 dominant and indicator plant species of the southwestern United States (herein referred to as the Southwest) and then conducted a coarse assessment of potential future changes in the distribution of their suitable habitat under three climate-change scenarios for two time periods. We used Maxent-based spatial modeling to predict the modern-day and future scenarios of SH for each species in an over 342-million-acre area encompassing all or parts of six states in the Southwest--Arizona, California, Colorado, Nevada, New Mexico, and Utah. Modern-day SH models were predicted by our using 26 annual and monthly average temperature and precipitation variables, averaged for the years 1971-2000. Future SH models were predicted for each species by our using six climate models based on application of the average of 16 General Circulation Models to Intergovernmental Panel on Climate Change emission scenarios B1, A1B, and A2 for two time periods, 2040 to 2069 and 2070 and 2100, referred to respectively as the 2050 and 2100 time periods. The assessment examined each species' vulnerability to loss of modern-day SH under future climate scenarios, potential to gain SH under future climate scenarios, and each species' estimated risk as a function of both vulnerability and potential gains. All 166 species were predicted to lose modern-day SH in the future climate change scenarios. In the 2050 time period, nearly 30 percent of the species lost 75 percent or more of their modern-day suitable habitat, 21 species gained more new SH than their modern-day SH, and 30 species gained less new SH than 25 percent of their modern-day SH. In the 2100 time period, nearly half of the species lost 75 percent or more of their modern-day SH, 28 species gained more new SH than their modern-day SH, and 34 gained less new SH than 25 percent of their modern-day SH. Using nine risk categories we found only two species were in the least risk category, while 20 species were in the highest risk category. The assessment showed that species respond independently to predicted climate change, suggesting that current plant assemblages may disassemble under predicted climate change scenarios. This report presents the results for each species in tables (Appendix A) and maps (14 for each species) in Appendix B.

  13. Win some, lose some: parental hypertension and heart rate change in an incentive versus response cost paradigm.

    PubMed

    Hastrup, J L; Johnson, C A; Hotchkiss, A P; Kraemer, D L

    1986-11-01

    Fowles (1983), citing evidence from separate studies, suggests that both incentive and response cost paradigms increase heart rate and should be subsumed under Gray's (1975) 'appetitive motivational system'. Shock avoidance and loss of reward (response cost) contingencies, while aversive, appear to evoke this motivational system; consequently both should elicit heart rate increases independent of anxiety. The present investigation compared magnitude of heart rate changes observed under conditions of winning and losing money. Results showed: no differences between incentive and response cost conditions; no effect of state anxiety on heart rate in these conditions, despite an elevation of state anxiety on the task day relative to a subsequent relaxation day assessment; and some evidence for the presence under both such appetitive conditions of cardiovascular hyperresponsivity among offspring of hypertensive parents. The results suggest a need for systematic parametric studies of experimental conditions.

  14. 38 CFR 59.160 - Adult day health care requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Adult day health care... (CONTINUED) GRANTS TO STATES FOR CONSTRUCTION OR ACQUISITION OF STATE HOMES § 59.160 Adult day health care requirements. As a condition for receiving a grant and grant funds under this part for an adult day health care...

  15. 38 CFR 59.160 - Adult day health care requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Adult day health care... (CONTINUED) GRANTS TO STATES FOR CONSTRUCTION OR ACQUISITION OF STATE HOMES § 59.160 Adult day health care requirements. As a condition for receiving a grant and grant funds under this part for an adult day health care...

  16. 38 CFR 59.160 - Adult day health care requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Adult day health care... (CONTINUED) GRANTS TO STATES FOR CONSTRUCTION OR ACQUISITION OF STATE HOMES § 59.160 Adult day health care requirements. As a condition for receiving a grant and grant funds under this part for an adult day health care...

  17. 38 CFR 59.160 - Adult day health care requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Adult day health care... (CONTINUED) GRANTS TO STATES FOR CONSTRUCTION OR ACQUISITION OF STATE HOMES § 59.160 Adult day health care requirements. As a condition for receiving a grant and grant funds under this part for an adult day health care...

  18. Snow Day Learning: First Years of Kentucky's Non-Traditional Instruction Days

    ERIC Educational Resources Information Center

    Hammons, Karen R.

    2017-01-01

    Non-traditional instruction days in Kentucky, as well as other states, are becoming increasingly popular as weather- and illness-related school closings compromise time in the classroom. This exploratory research study recounted the beginning of the use of non-traditional instruction days in the state of Kentucky as well as the current status…

  19. Molecular processes from the AGB to the PN stage

    NASA Astrophysics Data System (ADS)

    García-Hernández, D. Anibal

    2012-08-01

    Many complex organic molecules and inorganic solid-state compounds have been observed in the circumstellar shell of stars (both C-rich and O-rich) in the transition phase between Asymptotic Giant Branch (AGB) stars and Planetary Nebulae (PNe). This short (~102-104 years) phase of stellar evolution represents a wonderful laboratory for astrochemistry and provides severe constraints on any model of gas-phase and solid-state chemistry. One of the major challenges of present day astrophysics and astrochemistry is to understand the formation pathways of these complex organic molecules and inorganic solid-state compounds (e.g., polycyclic aromatic hydrocarbons, fullerenes, and graphene in the case of a C-rich chemistry and oxides and crystalline silicates in O-rich environments) in space. In this review, I present an observational review of the molecular processes in the late stages of stellar evolution with a special emphasis on the first detections of fullerenes and graphene in PNe.

  20. Winter day lengths counteract stimulatory effects of apomorphine and yohimbine on sexual behavior of male Syrian hamsters.

    PubMed

    Piekarski, David J; Jarjisian, Stephan G; Zucker, Irving

    2012-08-01

    Yohimbine and apomorphine selectively act on noradrenergic and dopaminergic neural substrates to augment male sexual behavior (MSB) in several rodent species. The present study assessed whether these drugs can overcome the suppressive effects of short winter-like day lengths on MSB. Yohimbine treatments that markedly increase copulatory behavior of male hamsters in long days were completely ineffective in facilitating MSB when injected after gonadal regression induced by 16 wks of short day lengths and after complete gonadal recrudescence after 32 wks of short days; apomorphine was similarly ineffective. The brain circuit that mediates MSB either may be less responsive to yohimbine and apomorphine in short than long days, or these drugs may not produce equivalent neurotransmitter changes in the two day lengths. After 32 wks of short-day treatment, all males had undergone testicular recrudescence and successfully ejaculated on initial tests with sexually receptive females after a hiatus of at least 4 mo during which they were denied mating opportunities. This suggests that overwintering males in the field are in a state of reproductive readiness at the outset of spring conditions favorable for survival of offspring.

  1. Molecular controlled of quantum nano systems

    NASA Astrophysics Data System (ADS)

    Paltiel, Yossi

    2014-03-01

    A century ago quantum mechanics created a conceptual revolution whose fruits are now seen in almost any aspect of our day-to-day life. Lasers, transistors and other solid state and optical devices represent the core technology of current computers, memory devices and communication systems. However, all these examples do not exploit fully the quantum revolution as they do not take advantage of the coherent wave-like properties of the quantum wave function. Controlled coherent system and devices at ambient temperatures are challenging to realize. We are developing a novel nano tool box with control coupling between the quantum states and the environment. This tool box that combines nano particles with organic molecules enables the integration of quantum properties with classical existing devices at ambient temperatures. The nano particles generate the quantum states while the organic molecules control the coupling and therefore the energy, charge, spin, or quasi particle transfer between the layers. Coherent effects at ambient temperatures can be measured in the strong coupling regime. In the talk I will present our nano tool box and show studies of charge transfer, spin transfer and energy transfer in the hybrid layers as well as collective transfer phenomena. These enable the realization of room temperature operating quantum electro optical devices. For example I will present in details, our recent development of a new type of chiral molecules based magnetless universal memory exploiting selective spin transfer.

  2. National Academy of Sciences-Academy of Sciences of the USSR Workshop on the Mechanics of Ice and Its Applications Held in Moscow and Leningrad on June 16-26, 1991

    DTIC Science & Technology

    1993-01-01

    interaction: Ice forces on offshore structures were reviewed. Presentations were given on practices employed in the United States to derive ice design ...Mechanics Workshop, four days were strictly devoted to presentaticns. ’he American presentations were quite varied with heavy eaphasis on experimental and...institute coducts investigaticrs that contribute to specific ship designs , but does not do the actual designs itself. Similarly, Krylov cmVIucts

  3. Second Annual Workshop on Space Operations Automation and Robotics (SOAR 1988)

    NASA Technical Reports Server (NTRS)

    Griffin, Sandy (Editor)

    1988-01-01

    Papers presented at the Second Annual Workshop on Space Operation Automation and Robotics (SOAR '88), hosted by Wright State University at Dayton, Ohio, on July 20, 21, 22, and 23, 1988, are documented herein. During the 4 days, approximately 100 technical papers were presented by experts from NASA, the USAF, universities, and technical companies. Panel discussions on Human Factors, Artificial Intelligence, Robotics, and Space Systems were held but are not documented herein. Technical topics addressed included knowledge-based systems, human factors, and robotics.

  4. The Information Economy in the U.S.: Its Effect on Libraries and Library Networks. Proceedings of the Library of Congress Network Advisory Committee Meeting (Washington, D.C., November 14-16, 1984). Network Planning Paper No. 10.

    ERIC Educational Resources Information Center

    Library of Congress, Washington, DC. Network Development Office.

    At a 2-day meeting in November 1984, the Library of Congress Network Advisory Committee (NAC) discussed the information economy in the United States and its effect on libraries and library networks. Material presented at the meeting is included in the form of summaries of three papers on the program theme presented by Ronald F. Miller, Kenneth W.…

  5. Medical serials control systems by computer--a state of the art review.

    PubMed Central

    Brodman, E; Johnson, M F

    1976-01-01

    A review of the problems encountered in serials control systems is followed by a description of some of the present-day attempts to solve these problems. Specific networks are described, notably PHILSOM (developed at Washington University School of Medicine Library), the UCLA Biomedical Library's system, and OCLC in Columbus, Ohio. Finally, the role of minicomputers in present and future developments is discussed, and some cautious guesses are made on future directions in the field. PMID:1247704

  6. Quantum teleportation and entanglement swapping of electron spins in superconducting hybrid structures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bubanja, Vladimir, E-mail: vladimir.bubanja@callaghaninnovation.govt.nz

    2015-06-15

    We present schemes for quantum teleportation and entanglement swapping of electronic spin states in hybrid superconductor–normal-metal systems. The proposed schemes employ subgap transport whereby the lowest order processes involve Cooper pair-electron and double Cooper-pair cotunneling in quantum teleportation and entanglement swapping protocols, respectively. The competition between elastic cotunneling and Cooper-pair splitting results in the success probability of 25% in both cases. Described implementations of these protocols are within reach of present-day experimental techniques.

  7. A case of acyclovir neurotoxicity presenting with atypical cerebrospinal fluid findings.

    PubMed

    Thind, Guramrinder Singh; Roach, Richard

    2017-05-22

    An 82-year-old man with a history of end-stage renal disease presented with progressively worsening confusion and somnolence for the past 4-5 days. The patient was diagnosed with herpes zoster by his primary care physician 5 days ago and was started on a course of valacyclovir 1 g three times a day (dose not adjusted for renal impairment).A lumbar puncture was performed and cerebrospinal fluid (CSF) studies revealed 37 white blood cells (WBCs)/hpf (100% monocytes), protein 64 mg/dL and glucose 52 mg/dL. He was started on ceftriaxone, ampicillin and acyclovir. MRI of the brain was done and was unremarkable. Acyclovir-induced encephalopathy was high on differential, but his CSF findings were concerning for viral encephalitis. Nonetheless, all antimicrobials were discontinued and he was scheduled for a 5-hour dialysis session. The very next day, he showed immense improvement and eventually recovered completely. CSF PCR tests for both herpes simplex virus and varicella zoster virus came back negative. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  8. Fibroblast growth factor 21 levels in young healthy females display day and night variations and are increased in response to short-term energy deprivation through a leptin-independent pathway.

    PubMed

    Foo, Joo-Pin; Aronis, Konstantinos N; Chamberland, John P; Paruthi, Jason; Moon, Hyun-Seuk; Mantzoros, Christos S

    2013-04-01

    Fibroblast growth factor (FGF)-21 is an endocrine factor with potent metabolic effects. Its day-night patterns of secretion and/or its physiological response to energy deprivation and relationship to free fatty acids (FFAs) and/or leptin remain to be fully elucidated. We aim to elucidate day-night pattern of FGF-21 levels and its relationship to FFA, to assess whether energy deprivation alters its circulating patterns, and to examine whether leptin may mediate these changes. Six healthy lean females were studied for 72 h in a cross-over interventional study under three different conditions: on isocaloric diet and in a fasting state with administration of either placebo or metreleptin in physiological replacement doses. Blood samples were obtained hourly from 8:00 a.m. on day 4 until 8:00 a.m. on day 5. FGF-21 exhibited day-night variation pattern during the isocaloric fed state. Fasting significantly increased FGF-21 levels (P < 0.01) via a leptin-independent pathway. Day-night variation pattern in the fed state was lost on fasting. Leptin replacement in the hypoleptinemic state restored approximate entropy of FGF-21 time series but did not alter circulating levels. FGF-21 levels were closely cross-correlated with FFA levels in all three states. A day-night variation in the levels of FGF-21 exists in young lean females in the fed state. Energy deprivation increases FGF-21 levels via a leptin-independent pathway. The interaction between FGF-21 and starvation-induced lipolysis, as indicated by its close cross-correlations with FFA in both fed state and energy deprivation, needs to be studied further.

  9. 77 FR 62137 - German-American Day, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-12

    ...-American Day, 2012 By the President of the United States of America A Proclamation United by dreams of... laws of the United States, do hereby proclaim October 6, 2012, as German-American Day. I encourage all... have made to our Nation. [[Page 62138

  10. [Correction of acute psychotic states in schizophrenia by rispolept solution per os].

    PubMed

    Panteleeva, G P; Korenev, A N; Barkhatova, A N

    2004-01-01

    To stop acute psychotic states during the first episode or relapses of schizophrenia, 37 patients were treated with rispolept solution per os during 2 weeks. A procedure of a fast transition to optimal daily doses of the drug after 1 day of treatment (searching period) with a following stabilization of mean daily doses (5.02-5.7 mg) at the stage of 14 day treatment course was used. Positive therapeutic effect by PANSS total score reduction, along with minor side-effects, were found in 91.9% patients. Stopping effect of rispolept on acute psychotic states, emerging from day 1 of the treatment, and general antipsychotic and therapeutic action, beginning from day 2-3 and increasing to day 14, were stated out. Efficacy of the drug in syndromes differing by psychopathological structure is emphasized.

  11. Intravenous Artesunate for the Treatment of Severe and Complicated Malaria in the United States: Clinical Use Under an Investigational New Drug Protocol.

    PubMed

    Twomey, Patrick S; Smith, Bryan L; McDermott, Cathy; Novitt-Moreno, Anne; McCarthy, William; Kachur, S Patrick; Arguin, Paul M

    2015-10-06

    Quinidine gluconate, the only U.S. Food and Drug Administration-approved treatment for life-threatening malaria in the United States, has a problematic safety profile and is often unavailable in hospitals. To assess the safety and clinical benefit of intravenous artesunate as an alternative to quinidine. Retrospective case series. U.S. hospitals. 102 patients aged 1 to 72 years (90% adults; 61% men) with severe and complicated malaria. Patients received 4 weight-based doses of intravenous artesunate (2.4 mg/kg) under a treatment protocol implemented by the Centers for Disease Control and Prevention between January 2007 and December 2010. At baseline, 35% had evidence of cerebral malaria, and 17% had severe hepatic impairment. Eligibility required the presence of microscopically confirmed malaria, need for intravenous treatment, and an impediment to quinidine. Clinical and laboratory data from each patient's hospital records were abstracted retrospectively, including information from baseline through a maximum 7-day follow-up, and presented before a physician committee to evaluate safety and clinical benefit outcomes. 7 patients died (mortality rate, 6.9%). The most frequent adverse events were anemia (65%) and elevated hepatic enzyme levels (49%). All deaths and most adverse events were attributed to the severity of malaria. Patients' symptoms generally improved or resolved within 3 days, and the median time to discharge from the intensive care unit was 4 days, even for patients with severe liver disease or cerebral malaria. More than 100 concomitant medications were used, with no documented drug-drug interactions. Potential late-presenting safety issues might occur outside the 7-day follow-up. Artesunate was a safe and clinically beneficial alternative to quinidine.

  12. Impact of a visual aid on discordance between physicians and family members about prognosis of critically ill patients.

    PubMed

    Burelli, Gabrielle; Berthelier, Chloé; Vanacker, Hélène; Descaillot, Léonard; Philippon-Jouve, Bénédicte; Fabre, Xavier; Kaaki, Mahmoud; Chakarian, Jean-Charles; Domine, Alexandre; Beuret, Pascal

    2018-06-01

    This study aimed to evaluate the impact of a visual aid on the discordance about prognosis between physicians and family members. The study was performed in a general intensive care department with two 6-bed units. In the unit A, family members could consult a visual aid depicting day by day the evolution of global, hemodynamic, respiratory, renal and neurological conditions of the patient on a 10-point scale. In the unit B, they only received oral medical information. On day 7 of the ICU stay, the physician and family members estimated the prognosis of the patient among four proposals (life threatened; steady state but may worsen; steady state, should heal; will heal). Then we compared the rate of discordance about prognosis between physicians and family members in the two units. Seventy-nine consecutive patients admitted in the intensive care department and still present at day 7, their family members and physicians, were enrolled. Patients in the two units were comparable in age, sex ratio, reason for admission, SAPS II at admission and SOFA score at day 7. In the unit A, physician-family members discordance about prognosis occurred for 12 out of 39 patients (31%) vs. 22 out of 40 patients (55%) in the unit B (P=0.04). In our study, adding a visual aid depicting the evolution of the condition of critically ill patients day by day to classic oral information allowed the family to have an estimate of the prognosis less discordant with the estimate of the physician. Copyright © 2018 Société française d'anesthésie et de réanimation (Sfar). Published by Elsevier Masson SAS. All rights reserved.

  13. Potential Impacts of Future Warming and Land Use Changes on Intra-Urban Heat Exposure in Houston, Texas

    PubMed Central

    Conlon, Kathryn; Monaghan, Andrew; Hayden, Mary; Wilhelmi, Olga

    2016-01-01

    Extreme heat events in the United States are projected to become more frequent and intense as a result of climate change. We investigated the individual and combined effects of land use and warming on the spatial and temporal distribution of daily minimum temperature (Tmin) and daily maximum heat index (HImax) during summer in Houston, Texas. Present-day (2010) and near-future (2040) parcel-level land use scenarios were embedded within 1-km resolution land surface model (LSM) simulations. For each land use scenario, LSM simulations were conducted for climatic scenarios representative of both the present-day and near-future periods. LSM simulations assuming present-day climate but 2040 land use patterns led to spatially heterogeneous temperature changes characterized by warmer conditions over most areas, with summer average increases of up to 1.5°C (Tmin) and 7.3°C (HImax) in some newly developed suburban areas compared to simulations using 2010 land use patterns. LSM simulations assuming present-day land use but a 1°C temperature increase above the urban canopy (consistent with warming projections for 2040) yielded more spatially homogeneous metropolitan-wide average increases of about 1°C (Tmin) and 2.5°C (HImax), respectively. LSM simulations assuming both land use and warming for 2040 led to summer average increases of up to 2.5°C (Tmin) and 8.3°C (HImax), with the largest increases in areas projected to be converted to residential, industrial and mixed-use types. Our results suggest that urbanization and climate change may significantly increase the average number of summer days that exceed current threshold temperatures for initiating a heat advisory for metropolitan Houston, potentially increasing population exposure to extreme heat. PMID:26863298

  14. Optimization of an artificial-recharge-pumping system for water supply in the Maghaway Valley, Cebu, Philippines

    NASA Astrophysics Data System (ADS)

    Kawo, Nafyad Serre; Zhou, Yangxiao; Magalso, Ronnell; Salvacion, Lasaro

    2018-05-01

    A coupled simulation-optimization approach to optimize an artificial-recharge-pumping system for the water supply in the Maghaway Valley, Cebu, Philippines, is presented. The objective is to maximize the total pumping rate through a system of artificial recharge and pumping while meeting constraints such as groundwater-level drawdown and bounds on pumping rates at each well. The simulation models were coupled with groundwater management optimization to maximize production rates. Under steady-state natural conditions, the significant inflow to the aquifer comes from river leakage, whereas the natural discharge is mainly the subsurface outflow to the downstream area. Results from the steady artificial-recharge-pumping simulation model show that artificial recharge is about 20,587 m3/day and accounts for 77% of total inflow. Under transient artificial-recharge-pumping conditions, artificial recharge varies between 14,000 and 20,000 m3/day depending on the wet and dry seasons, respectively. The steady-state optimisation results show that the total optimal abstraction rate is 37,545 m3/day and artificial recharge is increased to 29,313 m3/day. The transient optimization results show that the average total optimal pumping rate is 36,969 m3/day for the current weir height. The transient optimization results for an increase in weir height by 1 and 2 m show that the average total optimal pumping rates are increased to 38,768 and 40,463 m3/day, respectively. It is concluded that the increase in the height of the weir can significantly increase the artificial recharge rate and production rate in Maghaway Valley.

  15. Do Welfare States Raise Welfare(d) Kids? Day-Care Institutions and Inequality in the Danish Welfare State

    ERIC Educational Resources Information Center

    Ringsmose, Charlotte; Winther-Lindqvist, Ditte Alexandra; Allerup, Peter

    2014-01-01

    There is an increasing focus on early-childhood education quality globally, reflecting a growing political awareness that education starts earlier than primary school, and that high quality in day-care influence children's learning and development. In Denmark, almost all children attend day-care, and day-care institutions are considered part of…

  16. Territorial expansion and primary state formation

    PubMed Central

    Spencer, Charles S.

    2010-01-01

    A major research problem in anthropology is the origin of the state and its bureaucratic form of governance. Of particular importance for evaluating theories of state origins are cases of primary state formation, whereby a first-generation state evolves without contact with any preexisting states. A general model of this process, the territorial-expansion model, is presented and assessed with archaeological data from six areas where primary states emerged in antiquity: Mesoamerica, Peru, Egypt, Mesopotamia, the Indus Valley, and China. In each case, the evidence shows a close correspondence in time between the first appearance of state institutions and the earliest expansion of the state's political-economic control to regions lying more than a day's round-trip from the capital. Although additional research will add detail and clarity to the empirical record, the results to date are consistent with the territorial-expansion model, which argues that the success of such long-distance expansion not only demanded the bureaucratization of central authority but also helped provide the resources necessary to underwrite this administrative transformation. PMID:20385804

  17. Territorial expansion and primary state formation.

    PubMed

    Spencer, Charles S

    2010-04-20

    A major research problem in anthropology is the origin of the state and its bureaucratic form of governance. Of particular importance for evaluating theories of state origins are cases of primary state formation, whereby a first-generation state evolves without contact with any preexisting states. A general model of this process, the territorial-expansion model, is presented and assessed with archaeological data from six areas where primary states emerged in antiquity: Mesoamerica, Peru, Egypt, Mesopotamia, the Indus Valley, and China. In each case, the evidence shows a close correspondence in time between the first appearance of state institutions and the earliest expansion of the state's political-economic control to regions lying more than a day's round-trip from the capital. Although additional research will add detail and clarity to the empirical record, the results to date are consistent with the territorial-expansion model, which argues that the success of such long-distance expansion not only demanded the bureaucratization of central authority but also helped provide the resources necessary to underwrite this administrative transformation.

  18. Overview of Pulse Detonation Propulsion Technology

    DTIC Science & Technology

    2001-04-01

    PROPULSION TECHNOLOGY M. L. Coleman CHEMICAL PROPULSION INFORMATION AGENCY THE JOHNS HOPKINS UNIVERSITY. WHITING SCHOOL OF ENGINEERING -COLUMBIA...U. 20 R. Santoro, "Advanced Propulsion Research: A Focus of the Penn State Propulsion Engineering Research Center," Chemical Propulsion Information...Detonation Engine ," AIAA 95-3155 (July 1995), U-A. NASA Marshall Space Flight Center Space Transportation Day 2000 Presentation Material, Advance Chemical

  19. Historical (1749-1899) vs. present-day sugar maple and beech diameter growth in the northeast

    Treesearch

    William B. Leak

    2011-01-01

    Possible environmental impacts in the Northeast from climate change, acid deposition, nutrient depletion, and other factors could retard tree growth and development in the northeastern United States. To gain insight into growth trends before the 20th century, approximately 150 years of radial growth records taken in 1899 on sugar maple and beech were examined and...

  20. [Biomedical foundation for human safety in aviation].

    PubMed

    Ushakov, I B

    2004-01-01

    According to the author, preventive medical issues of providing human safety in aviation are related to the fundamental biomedical and socio-psychological problems of human beings in the present-day world. Factual material for analysis was compiled in the study performed at the State Research and Test Institute of Military Medicine. Outlined are main vectors of the future attack on the problem.

  1. The Fed and the U.S. Constitution: Too Much Independence?

    ERIC Educational Resources Information Center

    Suiter, Mary C.; Schug, Mark C.

    2012-01-01

    Central banking in the United States has a long and controversial history dating back to the earliest days of the republic. One of the most widely presented arguments against a central bank has been that the U.S. Constitution does not expressly grant the federal government power to charter a bank. Recently, this issue has received new scrutiny in…

  2. The Teaching of Supranational Concepts in Geography.

    ERIC Educational Resources Information Center

    Coleman, John M.

    A primary goal of a teacher of regional geography should be to present the course as a study of the changing functions of world regions because the events of each day cause regions, whether political, economic, cultural, or physical, to be in constant flux. The nation-state has become in many ways out-moded as a source of analyzing the events of…

  3. Happiness Is Healthiness. A Special Study Institute in Health Education for Mentally Handicapped Children in Elementary and Secondary Schools.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau for Mentally Handicapped Children.

    Presented are proceedings from a 3-day study institute (1971) to provide teachers of mentally handicapped (MH) students, health profession personnel, and physical education teachers in Schenectady with resource information for implementation of New York state's mandate to provide health education for all children. Included are the program schedule…

  4. Extended Kinship in the United States: Competing Models and the Case of La Familia Chicana.

    ERIC Educational Resources Information Center

    Sena-Rivera, Jaime

    1979-01-01

    Extended kinship among Chicanos is explored through intensive open-ended interviews with four cases of three generations of Mexican-descent families. "La familia chicana" is posited as a modified extended or kin-integrated family extending over time and space from Mexico at the turn of the century to present day industrial America. (Author)

  5. Past, Present and Place: Three Activities from the We Are Wyoming Project

    ERIC Educational Resources Information Center

    Moran, Peter William; Trent, Allen

    2017-01-01

    The authors have had numerous opportunities to work with elementary teachers and students, but few of those experiences have been as rewarding as the We Are Wyoming project. During the 2014-2015 school year, they traveled to thirty-six fourth-grade classrooms all over the state teaching the We Are Wyoming project. The unit was a two-day integrated…

  6. 1889 Consular Dispatch from Baghdad

    ERIC Educational Resources Information Center

    Potter, Lee Ann

    2007-01-01

    In the late summer of 1888, officials at the U.S. Department of State appointed John Henry Haynes of Rowe, Massachusetts, to become the first U.S. consul in Baghdad. At that time, Baghdad--along with all of present day Iraq--was part of the Ottoman Empire, as it had been for more than three centuries. In his fourth dispatch, a single-page,…

  7. How well do terrestrial biosphere models simulate coarse-scale runoff in the contiguous United States?

    Treesearch

    C.R. Schwalm; D.N. Huntzinger; R.B. Cook; Y. Wei; I.T. Baker; R.P. Neilson; B. Poulter; Peter Caldwell; G. Sun; H.Q. Tian; N. Zeng

    2015-01-01

    Significant changes in the water cycle are expected under current global environmental change. Robust assessment of present-day water cycle dynamics at continental to global scales is confounded by shortcomings in the observed record. Modeled assessments also yield conflicting results which are linked to differences in model structure and simulation protocol. Here we...

  8. Community Assumes the Role of State in Education in Stateless Somalia

    ERIC Educational Resources Information Center

    Abdinoor, Abdullahi

    2008-01-01

    Education contributes, in peace time and war time, to the cultivation of human capital as well as social capital of the society. It is in this light that this article seeks to explore the close interplay between education and the community in the present-day stateless Somalia. In order to explore how the Somali community has coped or is coping…

  9. Poems about Sandwich Cookies, Jelly, and Chocolate: Poetry in K-3 Classrooms

    ERIC Educational Resources Information Center

    McNair, Jonda C.

    2012-01-01

    The author had presented a session on poetry at a children's literature conference sponsored by The Ohio State University, and afterward two teachers invited her to come to their school and read poetry. The children emailed their responses to her shortly after she spent the entire day conducting poetry reading sessions at an elementary school in…

  10. Plasma wall interaction, a key issue on the way to a steady state burning fusion device

    NASA Astrophysics Data System (ADS)

    Philipps, V.

    2006-04-01

    The International Tokamak Experimental Reactor (ITER), the first burning fusion plasma experiment based on the tokamak principle, is ready for construction. It is based on many years of fusion research resulting in a robust design in most of the areas. Present day fusion research concentrates on the remaining critical issues which are, to a large extent, connected with processes of plasma wall interaction. This is mainly due to extended duty cycle and the increase of the plasma stored energy in comparison with present-day machines. Critical topics are the lifetime of the plasma facing components (PFC) and the long-term tritium retention. These processes are controlled mainly by material erosion, both during steady state operation and transient power losses (disruptions and edge localized modes (ELMs)) and short- and long-range material migration and re-deposition. The extrapolation from present-day 'full carbon wall' devices suggests that the long-term tritium retention in a burning fusion device would be unacceptably high under these conditions allowing for only an unacceptable limited number of pulses in a D T mixture. As a consequence of this, research activities have been strengthened to understand in more detail the underlying processes of material erosion and re-deposition, to develop methods to remove retained tritium from the PFCs and remote areas of a fusion device and to explore these processes and the plasma performance in more detail with metallic PFC, such as beryllium (Be) and tungsten (W), which are foreseen for the ITER experiment. This paper outlines the main physical mechanisms leading to material erosion, migration and re-deposition and the associated fuel retention. It addresses the experimental database in these areas and describes the further research strategies that will be needed to tackle critical issues.

  11. Cloud Response to Arctic Sea Ice Loss and Implications for Feedbacks in the CESM1 Climate Model

    NASA Astrophysics Data System (ADS)

    Morrison, A.; Kay, J. E.; Chepfer, H.; Guzman, R.; Bonazzola, M.

    2017-12-01

    Clouds have the potential to accelerate or slow the rate of Arctic sea ice loss through their radiative influence on the surface. Cloud feedbacks can therefore play into Arctic warming as clouds respond to changes in sea ice cover. As the Arctic moves toward an ice-free state, understanding how cloud - sea ice relationships change in response to sea ice loss is critical for predicting the future climate trajectory. From satellite observations we know the effect of present-day sea ice cover on clouds, but how will clouds respond to sea ice loss as the Arctic transitions to a seasonally open water state? In this study we use a lidar simulator to first evaluate cloud - sea ice relationships in the Community Earth System Model (CESM1) against present-day observations (2006-2015). In the current climate, the cloud response to sea ice is well-represented in CESM1: we see no summer cloud response to changes in sea ice cover, but more fall clouds over open water than over sea ice. Since CESM1 is credible for the current Arctic climate, we next assess if our process-based understanding of Arctic cloud feedbacks related to sea ice loss is relevant for understanding future Arctic clouds. In the future Arctic, summer cloud structure continues to be insensitive to surface conditions. As the Arctic warms in the fall, however, the boundary layer deepens and cloud fraction increases over open ocean during each consecutive decade from 2020 - 2100. This study will also explore seasonal changes in cloud properties such as opacity and liquid water path. Results thus far suggest that a positive fall cloud - sea ice feedback exists in the present-day and future Arctic climate.

  12. Cosmopolitan sociology and the classical canon: Ferdinand Tönnies and the emergence of global Gesellschaft.

    PubMed

    Inglis, David

    2009-12-01

    How relevant are figures from the classical sociological canon for present day efforts to found cosmopolitan forms of sociological thought? According to the critique of Ulrich Beck, the classical sociologists remain far too wedded to nation-state-centred ways of thinking to play an important role in the development of cosmopolitan sociology. This paper argues that such a critique fails to account for the ways in which certain classical sociologists were attuned to the emerging cosmopolitical conditions of their own time, were not wholly wedded to nation-state-based conceptualizations, and thus can function as both groundings of, and inspirations for, cosmopolitan sociological endeavours. The apparently unpromising case of Tönnies is focused on, the paper showing how he outlined an account of how and why a planet-spanning condition of Gesellschaft developed a position which diverges from and counterpoints Marx's analysis of similar phenomena in important ways. The stereotype of Tönnies as an arch-conservative is also dissolved, allowing him to be considered as one of the most important antecedents of contemporary cosmopolitan sociological practice and a canonical figure still relevant for present-day purposes.

  13. Social Variations in Perceived Parenting Styles among Norwegian Adolescents.

    PubMed

    Elstad, Jon Ivar; Stefansen, Kari

    2014-01-01

    Previous research has documented the associations between parenting and parenting styles and child and adolescent outcomes. Little is known, however, about the social structuring of parenting in contemporary Nordic welfare states. A possible hypothesis is that socioeconomic variations in parenting styles in present-day Norway will be small because of material affluence, limited income inequality, and an active welfare state. This study examines social variations in parenting as perceived by Norwegian adolescents ( N  = 1362), with a focus on four parenting style dimensions: responsiveness, demandingness, neglecting, and intrusive. Responsiveness seems to capture major divisions in parenting. Adolescents in families with fewer economic resources experienced their parents as somewhat less responsive, but responsiveness was not related to parents' education. Low parental education was on the other hand associated with perceptions of parents as neglecting and intrusive. Viewing parents as demanding did neither vary with parental education nor with family economy. Substantial variations in parenting styles persist in present-day Norway, and these variations correspond moderately with the families' placement in the social structure. Indicators of parenting and parenting styles may be useful indicators of some aspects of child and adolescent well-being.

  14. A case of butane hash oil (marijuana wax)-induced psychosis.

    PubMed

    Keller, Corey J; Chen, Evan C; Brodsky, Kimberly; Yoon, Jong H

    2016-01-01

    Marijuana is one of the most widely used controlled substances in the United States. Despite extensive research on smoked marijuana, little is known regarding the potential psychotropic effects of marijuana "wax," a high-potency form of marijuana that is gaining in popularity. The authors present a case of "Mr. B," a 34-year-old veteran who presented with profound psychosis in the setting of recent initiation of heavy, daily marijuana wax use. He exhibited incoherent speech and odd behaviors and appeared to be in a dream-like state with perseverating thoughts about his combat experience. His condition persisted despite treatment with risperidone 4 mg twice a day (BID), but improved dramatically on day 8 of hospitalization with the return of baseline mental function. Following discharge, Mr. B discontinued all marijuana use and did not exhibit the return of any psychotic symptoms. This study highlights the need for future research regarding the potential medical and psychiatric effects of new, high-potency forms of marijuana. Could cannabis have a dose-dependent impact on psychosis? What other potential psychiatric effects could emerge heretofore unseen in lower potency formulations? Given the recent legalization of marijuana, these questions merit timely exploration.

  15. 75 FR 27574 - United States Park Police; 60-Day Notice of Intention To Request Clearance of Collection of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-17

    ... DEPARTMENT OF THE INTERIOR National Park Service United States Park Police; 60-Day Notice of... States Park Police, National Park Service, Interior. ACTION: Notice and request for comments. SUMMARY... Keeping Requirements, the United States Park Police (USPP) invites public comments on an extension of a...

  16. Psychophysiological responses of junior orienteers under competitive pressure.

    PubMed

    Robazza, Claudio; Izzicupo, Pascal; D'Amico, Maria Angela; Ghinassi, Barbara; Crippa, Maria Chiara; Di Cecco, Vincenzo; Ruiz, Montse C; Bortoli, Laura; Di Baldassarre, Angela

    2018-01-01

    The purpose of the study was to examine psychobiosocial states, cognitive functions, endocrine responses (i.e., salivary cortisol and chromogranin A), and performance under competitive pressure in orienteering athletes. The study was grounded in the individual zones of optimal functioning (IZOF) and biopsychosocial models. Fourteen junior orienteering athletes (7 girls and 7 boys), ranging in age from 15 to 20 years (M = 16.93, SD = 1.77) took part in a two-day competitive event. To enhance competitive pressure, emphasis was placed on the importance of the competition and race outcome. Psychophysiological and performance data were collected at several points before, during, and after the races. Results showed that an increase in cortisol levels was associated with competitive pressure and reflected in higher perceived exertion (day 1, r = .32; day 2, r = .46), higher intensity of dysfunctional states (day 1, r = .59; day 2, r = .55), lower intensity of functional states (day 1, r = -.36; day 2, r = -.33), and decay in memory (day 1, r = -.27; day 2, r = -.35), visual attention (day 1, r = -.56; day 2, r = -.35), and attention/mental flexibility (day 1, r = .16; day 2, r = .26) tasks. The second day we observed better performance times, lower intensity of dysfunctional states, lower cortisol levels, improved visual attention and attention/mental flexibility (p < .050). Across the two competition days, chromogranin A levels were higher (p < .050) on the most difficult loops of the race in terms of both physical and psychological demands. Findings suggest emotional, cognitive, psychophysiological, and performance variables to be related and to jointly change across different levels of cognitive and physical load. Overall results are discussed in light of the IZOF and biopsychosocial models. The procedure adopted in the study also supports the feasibility of including additional cognitive load for possible practical applications.

  17. Psychophysiological responses of junior orienteers under competitive pressure

    PubMed Central

    Izzicupo, Pascal; D’Amico, Maria Angela; Ghinassi, Barbara; Crippa, Maria Chiara; Di Cecco, Vincenzo; Ruiz, Montse C.; Bortoli, Laura; Di Baldassarre, Angela

    2018-01-01

    The purpose of the study was to examine psychobiosocial states, cognitive functions, endocrine responses (i.e., salivary cortisol and chromogranin A), and performance under competitive pressure in orienteering athletes. The study was grounded in the individual zones of optimal functioning (IZOF) and biopsychosocial models. Fourteen junior orienteering athletes (7 girls and 7 boys), ranging in age from 15 to 20 years (M = 16.93, SD = 1.77) took part in a two-day competitive event. To enhance competitive pressure, emphasis was placed on the importance of the competition and race outcome. Psychophysiological and performance data were collected at several points before, during, and after the races. Results showed that an increase in cortisol levels was associated with competitive pressure and reflected in higher perceived exertion (day 1, r = .32; day 2, r = .46), higher intensity of dysfunctional states (day 1, r = .59; day 2, r = .55), lower intensity of functional states (day 1, r = -.36; day 2, r = -.33), and decay in memory (day 1, r = -.27; day 2, r = -.35), visual attention (day 1, r = -.56; day 2, r = -.35), and attention/mental flexibility (day 1, r = .16; day 2, r = .26) tasks. The second day we observed better performance times, lower intensity of dysfunctional states, lower cortisol levels, improved visual attention and attention/mental flexibility (p < .050). Across the two competition days, chromogranin A levels were higher (p < .050) on the most difficult loops of the race in terms of both physical and psychological demands. Findings suggest emotional, cognitive, psychophysiological, and performance variables to be related and to jointly change across different levels of cognitive and physical load. Overall results are discussed in light of the IZOF and biopsychosocial models. The procedure adopted in the study also supports the feasibility of including additional cognitive load for possible practical applications. PMID:29698498

  18. Super-large optical gyroscopes for applications in geodesy and seismology: state-of-the-art and development prospects

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Velikoseltsev, A A; Luk'yanov, D P; Vinogradov, V I

    2014-12-31

    A brief survey of the history of the invention and development of super-large laser gyroscopes (SLLGs) is presented. The basic results achieved using SLLGs in geodesy, seismology, fundamental physics and other fields are summarised. The concept of SLLG design, specific features of construction and implementation are considered, as well as the prospects of applying the present-day optical technologies to laser gyroscope engineering. The possibilities of using fibre-optical gyroscopes in seismologic studies are analysed and the results of preliminary experimental studies are presented. (laser gyroscopes)

  19. New perspectives on evolutionary medicine: the relevance of microevolution for human health and disease.

    PubMed

    Rühli, Frank Jakobus; Henneberg, Maciej

    2013-04-29

    Evolutionary medicine (EM) is a growing field focusing on the evolutionary basis of human diseases and their changes through time. To date, the majority of EM studies have used pure theories of hominin macroevolution to explain the present-day state of human health. Here, we propose a different approach by addressing more empirical and health-oriented research concerning past, current and future microevolutionary changes of human structure, functions and pathologies. Studying generation-to-generation changes of human morphology that occurred in historical times, and still occur in present-day populations under the forces of evolution, helps to explain medical conditions and warns clinicians that their current practices may influence future humans. Also, analyzing historic tissue specimens such as mummies is crucial in order to address the molecular evolution of pathogens, of the human genome, and their coadaptations.

  20. Frequency of Tobacco Use Among Middle and High School Students -- United States, 2014

    MedlinePlus

    ... during the preceding 30 days — National Youth Tobacco Survey, United States, 2014 Days of use Tobacco product ... smokers, and smokeless tobacco users † — National Youth Tobacco Survey, United States, 2014 * Current use was assessed for ...

  1. Day/night changes in serum S100B protein concentrations in acute paranoid schizophrenia.

    PubMed

    Morera-Fumero, Armando L; Díaz-Mesa, Estefanía; Abreu-Gonzalez, Pedro; Fernandez-Lopez, Lourdes; Cejas-Mendez, Maria Del Rosario

    2017-04-03

    There are day/night and seasonal changes in biological markers such as melatonin and cortisol. Controversial changes in serum S100B protein levels have been described in schizophrenia. We aim studying whether serum S100B levels present day/night variations in schizophrenia patients and whether S100B levels are related to psychopathology. Sixty-five paranoid schizophrenic inpatients participated in the study. Psychopathology was assessed with the Positive and Negative Syndrome Scale (PANSS) at admission and discharge. Blood was drawn at 12:00 (midday) and 00:00 (midnight) hours at admission and discharge. Sixty-five healthy subjects matched by age, gender and season acted as control group. At admission and discharge patients had significantly higher serum S100B concentrations at midday and midnight than healthy subjects. At admission, patients showed a day/night variation of S100B levels, with higher S100B levels at 12:00 than at 00:00h (143.7±26.3pg/ml vs. 96.9±16.6pg/ml). This day/night difference was not present in the control group. Midday and midnight S100B at admission decreased when compared to S100B at discharge (midday, 143.7±26.3 vs. 83.0±12, midnight 96.9±16.6 vs. 68.6±14.5). There was a positive correlation between the PANSS positive subscale and S100B concentrations at admission. This correlation was not present at discharge. acute paranoid schizophrenia inpatients present a day/night change of S100B serum levels at admission that disappears at discharge. The correlation between serum S100B concentrations and the PANSS positive scores at admission as well as the decrease of S100B at discharge may be interpreted as an acute biological response to the clinical state of the patients. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  2. Spontaneous coronary artery dissection in a young woman with polycystic ovarian syndrome.

    PubMed

    Mirra, Marco; Kola, Nertil; Mattiello, Giacomo; Morisco, Carmine; Spinelli, Letizia

    2017-06-01

    Polycystic ovarian syndrome (PCOS) affects 4% to 12% of women in reproductive age, representing a clinical condition that could predispose to cardiovascular diseases. We report a case of a 34-year-old woman with PCOS, presenting with chest pain, onset two days before, and ST segment-elevation myocardial infarction. She was not pregnant or in a postpartum state. Subsequent cardiac angiography revealed spontaneous left anterior descending coronary artery dissections, managed by conservative approach. The patient was discharged in medical therapy after 5days. This is the first observation of spontaneous coronary artery dissection occurring in a PCOS patient. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. On the effect of the neutral Hydrogen density on the 26 day variations of galactic cosmic rays

    NASA Astrophysics Data System (ADS)

    Engelbrecht, Nicholas; Burger, Renier; Ferreira, Stefan; Hitge, Mariette

    Preliminary results of a 3D, steady-state ab-initio cosmic ray modulation code are presented. This modulation code utilizes analytical expressions for the parallel and perpendicular mean free paths based on the work of Teufel and Schlickeiser (2003) and Shalchi et al. (2004), incorporating Breech et al. (2008)'s model for the 2D variance, correlation scale, and normalized cross helicity. The effects of such a model for basic turbulence quantities, coupled with a 3D model for the neutral Hydrogen density on the 26-day variations of cosmic rays, is investigated, utilizing a Schwadron-Parker hybrid heliospheric magnetic field.

  4. A Critical Appraisal of the "Day" Diagram

    NASA Astrophysics Data System (ADS)

    Roberts, Andrew P.; Tauxe, Lisa; Heslop, David; Zhao, Xiang; Jiang, Zhaoxia

    2018-04-01

    The "Day" diagram (Day et al., 1977, https://doi.org/10.1016/0031-9201(77)90108-X) is used widely to make inferences about the domain state of magnetic mineral assemblages. Based on theoretical and empirical arguments, the Day diagram is demarcated into stable "single domain" (SD), "pseudo single domain" ("PSD"), and "multidomain" (MD) zones. It is straightforward to make the necessary measurements for a sample and to plot results within the "domain state" framework based on the boundaries defined by Day et al. (1977, https://doi.org/10.1016/0031-9201(77)90108-X). We discuss 10 issues that limit Day diagram interpretation, including (1) magnetic mineralogy, (2) the associated magnetocrystalline anisotropy type, (3) mineral stoichiometry, (4) stress state, (5) surface oxidation, (6) magnetostatic interactions, (7) particle shape, (8) thermal relaxation, (9) magnetic particle mixtures, and (10) definitional/measurement issues. In most studies, these variables are unknowns and cannot be controlled for, so that hysteresis parameters for single bulk samples are nonunique and any data point in a Day diagram could result from infinite combinations of relevant variables. From this critical appraisal, we argue that the Day diagram is fundamentally ambiguous for domain state diagnosis. Widespread use of the Day diagram has also contributed significantly to prevalent but questionable views, including underrecognition of the importance of stable SD particles in the geological record and reinforcement of the unhelpful PSD concept and of its geological importance. Adoption of approaches that enable correct domain state diagnosis should be an urgent priority for component-specific understanding of magnetic mineral assemblages and for quantitative rock magnetic interpretation.

  5. Full-Day Kindergarten: A Look across the States. 50-State Review

    ERIC Educational Resources Information Center

    Parker, Emily; Diffey, Louisa; Atchison, Bruce

    2016-01-01

    Research indicates that a high-quality, full-day kindergarten experience is a crucial component to setting students up for ongoing academic success, yet vast differences exist in the quality of kindergarten programs and how they are funded across the states. As states continue to develop strong pre-kindergarten (pre-K) programs, many are also…

  6. Population ecology of the mallard: IV. A review of duck hunting regulations, activity, and success, with special reference to the mallard

    USGS Publications Warehouse

    Martin, Elwood M.; Carney, Samuel M.

    1977-01-01

    This, the fourth in a series of reports on the mallard, (Anas platyrhynchos), deals at length with the harvest of mallards by waterfowl hunters. Long-term summaries of duck hunting regulations (1948- 1974), Migratory Bird Hunting Stamp sales (1934-1974), Hunter Questionnaire (1952-1974), Duck Wing Collection (1960-1974), and Hunter Performance (1965-1972) Survey data for the United States are presented and discussed. Similar data from Canada are also summarized. Mallard harvest figures for 1961-1974 are presented by Mallard Harvest Area, of which 100 are defined for the United States and 14 for Canada, as well as by State or Province and flyway.During the 23-year period beginning in 1952, an average of 1.6 million adult and 0.2 million junior waterfowl hunters accumulated almost 12.3 million hunter-days of recreation and a harvest of 11.2 million ducks each year. Hunter reports indicate that mallards made up about 43% (5.5 million annually) of the ducks taken before 1960, when mallard regulations were less restrictive; the Duck Wing Survey indicates that mallards have made up 33% of the harvest (3.6 million annually) since 1960. The age and sex compositions and the chronological distribution of the mallard harvest are examined in detail. Among the patterns noted are peak harvests during the first few days of the season in many States, alternately increasing and decreasing annual age ratios, and sex ratios that suggest differential migration of adult drakes and hunter selectivity for males. It is estimated that almost 19% of the ducks shot down are not retrieved.Relationships between duck hunting regulations and hunter behavior are examined briefly. Hunter compliance with mallard bag limits, hunter selectivity of mallards by sex, and, to a lesser extent, the size of the unretrieved kill are all sensitive to the particular bag limit regulations in effect. Survey data are also examined for relationships between harvest and various hunting regulations: starting time and day of the week for opening day, opening date, season length, split seasons, daily shooting hours, and daily bag limits. Tables are presented relating changes in duck and mallard harvests to season length and bag limit, and examples of what effects changes in other regulations have on harvest are also given.The evaluation of bag limit regulations, one of the most important tools used in managing harvest, is carried a step further with the development of a procedure for calculating expected hunter success under a wide variety of bag limit regulations. This method appears promising for evaluating point-limit as well as fixed-limit regulations. In addition, it may provide useful measurements of the degree of hunter selectivity induced by various types of bag limit regulations, an increasingly important aspect of harvest management. Finally, this study clearly demonstrates that the effects of a particular regulation can differ dramatically from area to area, so it is usually necessary to evaluate each proposal on a State-by-State basis.

  7. 78 FR 29147 - 30-Day Notice and Request for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-17

    ... DEPARTMENT OF HOMELAND SECURITY United States Secret Service 30-Day Notice and Request for... Management and Budget, Attn: Desk Officer for United States Secret Service, Department of Homeland Security... directed to: United States Secret Service, Security Clearance Division, Attn: ASAIC Michael Smith...

  8. RETURN OF THE KING: TIME-SERIES PHOTOMETRY OF FO AQUARII’S INITIAL RECOVERY FROM ITS UNPRECEDENTED 2016 LOW STATE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Littlefield, Colin; Garnavich, Peter; Kennedy, Mark R.

    In 2016 May, the intermediate polar FO Aqr was detected in a low state for the first time in its observational history. We report time-resolved photometry of the system during its initial recovery from this faint state. Our data, which includes high-speed photometry with cadences of just 2 s, show the existence of very strong periodicities at 22.5 and 11.26 minutes, equivalent to the spin–orbit beat frequency and twice its value, respectively. A pulse at the spin frequency is also present but at a much lower amplitude than is normally observed in the bright state. By comparing our power spectra withmore » theoretical models, we infer that a substantial amount of accretion was stream-fed during our observations, in contrast to the disk-fed accretion that dominates the bright state. In addition, we find that FO Aqr’s rate of recovery has been unusually slow in comparison to rates of recovery seen in other magnetic cataclysmic variables, with an e -folding time of 115 ± 7 days. The recovery also shows irregular variations in the median brightness of as much as 0.2 mag over a 10-day span. Finally, we show that the arrival times of the spin pulses are dependent upon the system’s overall brightness.« less

  9. A developmental, body-oriented intervention for children and adolescents with medically unexplained chronic pain.

    PubMed

    Kozlowska, Kasia; Khan, Rubina

    2011-10-01

    The regulation of pain and other emotions is a developmental process that takes place in the context of attachment relationships. Children with chronic, medically unexplained pain struggle to accurately identify, communicate and regulate negative body states, and to connect these body states to their day-to-day experience. This article describes an individual intervention - one component of a multimodal treatment programme - whose aim is to help children find skills to manage their pain. The intervention incorporates ideas and practices from several theoretical models - the dynamic-maturational model of attachment, cognitive-behavioural theories, narrative therapy, art therapy, sensorimotor approaches -pragmatically selected and adapted to help children presenting to our Chronic Pain Service achieve good clinical outcomes. At the outset we assess the child's capacity to identify, regulate and communicate positive and negative body states, and tailor our individual intervention so as to extend each child's proximal level of development. We initially focus on the body in an effort to equip the child with a non-verbal, image-based language for identifying and communicating pain and other negative body states. Once the child has developed a non-verbal way of knowing her body, a range of cognitive-behavioural, narrative and other strategies are introduced. The intervention aims to increase the child's emotional functioning: her skill in identifying, symbolically representing, communicating and managing pain and other negative body states.

  10. Test of the X(3872) structure in antiproton-nucleus collisions

    NASA Astrophysics Data System (ADS)

    Larionov, Alexei; Strikman, Mark; Bleicher, Marcus

    2016-05-01

    The present day experimental data on the X(3872) decays do not allow us to make clear conclusions about the dominant structure of this state. We discuss here an alternative way to study its structure by means of the two-step D¯* (or D) production in p ¯A reactions. If this process is mediated by X(3872), the characteristic narrow peaks of the D¯* (or D) distributions in the light cone momentum fraction at small transverse momenta will appear. This would unambiguously signal the DD¯* + c.c. molecular composition of the X(3872) state.

  11. A case of hyperosmolar hyperglycaemic state with involuntary movements – diagnostic dilemma and clinical considerations

    PubMed Central

    Abd Hamid, Hanisah; Othman, Hanita; Das, Srijit

    2010-01-01

    Hyperosmolar hyperglycaemic state (HHS) is a medical emergency which needs immediate medical intervention. A 37-year-old Chinese woman with a history of hypertension attended the Emergency Department. She had a two-day history of involuntary movement, i.e. chorea of the upper limbs, preceded by a one-week history of upper respiratory tract infection. She also had polyuria and polydipsia, although she was never diagnosed as diabetic. The main aim of reporting the present case was to highlight the importance of biochemical investigations involved in the diagnosis of involuntary movements. PMID:22427779

  12. Economic feasibility of cooling dry cows across the United States.

    PubMed

    Ferreira, F C; Gennari, R S; Dahl, G E; De Vries, A

    2016-12-01

    Heat stress during the dry period reduces milk yield in the subsequent lactation of dairy cows. Our objectives were to quantify the economic losses due to heat stress if dry cows are not cooled and to evaluate the economic feasibility of dry cow cooling. We used weather data from the National Oceanic and Atmospheric Administration to calculate the number of heat stress days for each of the 50 US states. A heat stress day was declared when the daily average temperature-humidity index was ≥68. The number of dairy cows in each state in 2015 was obtained from the USDA-National Agricultural Statistics Service. We assumed that 15% of the cows were dry at any time, a 60-d dry period, and a calving interval of 400d. Only cows in their second or greater parity (65%) benefitted from cooling during the dry period of the previous parity. Milk yield decreased by 5kg in the subsequent lactation (340d) if the cow experienced heat stress during the dry period based on a review of the literature. The default marginal value of milk minus feed cost was $0.33/kg of milk. The investment analysis included purchases of fans and soakers and use of water and electricity. Investment in a dry cow barn was considered separately. The average US dairy cow would experience 96 (26%) heat stress days during the year if not cooled and loses 447kg of milk in the subsequent lactation if not cooled when dry. Annual losses would be $810 million if dry cows were not cooled ($87/cow per yr). For the top 3 milk-producing states (California, Wisconsin, New York), and Florida and Texas, the average milk losses in the subsequent lactation were 522, 349, 387, 1,197, and 904kg, and reduced profit per cow per year would be $101, $68, $75, $233, and $176, respectively. The average benefit-cost ratio and payback periods of cooling dry cows in the United States were 3.15 and 0.27 yr (dry cow barn already present) and 1.45 and 5.68 yr (if investing in a dry cow barn) in the default scenario. To reach positive net present values, 6d (barn is present) and 55d (barn investment necessary) of heat stress annually were necessary (default assumptions). Other benefits of cooling, such as increased health and more productive offspring, were not considered. In conclusion, cooling of dry cows was profitable for 89% of the cows in the United States when building a new barn is required (under default assumptions) and very profitable when construction of a dry cow barn is not required (except for Alaska). Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  13. The onshore Cenozoic basin development of the UK and its relation to present-day vertical surface motions

    NASA Astrophysics Data System (ADS)

    Smith, Philip; England, Richard; Zalasiewicz, Jan

    2017-04-01

    Historical long wavelength uplift and subsidence patterns in the UK have been assumed to reflect glacial isostatic adjustment. Shorter wavelength variations are generally neglected, and do not fit with glacial rebound models, hence they may give important clues to other processes driving vertical motions. Present day vertical surface motions are based on one generation of observed data and do not necessarily represent the long-term stress and tectonic configuration of the UK. Cenozoic strata can provide a record of long-term changes and potentially can indicate the drivers of present day short wavelength variations. Understanding the dominant controls on UK tectonics may have implications for petroleum systems, geotechnical assessments and anthropogenic impact factors. Here we apply stratigraphic backstripping techniques to determine Cenozoic vertical surface motions. To complete the dataset, we also backstripped the Pleistocene Crag formations of East Anglia which post-dated the substantial Miocene hiatus most likely caused by the main phase of Alpine orogenic development. These deposits, the youngest being 2.1 Ma pre-date the glacial maximum of the UK helping to bridge the gap between the early Cenozoic and recent events. Subsidence analysis of the sequence indicates larger subsidence rates and sediment accumulation in the Hampshire basin than in the rest of southeast England. Reactivation of Variscan faults during the deposition of Cenozoic sediments appears to have taken place concomitantly with tectonic shortening and suggests phases of compression affected the UK throughout the Paleogene and Neogene not dissimilar to the current stress state and earthquake record. From our data we may be able to understand the major tectonic controls influencing southern England during the Cenozoic and assess the nature of the transition to the vertical surface motion observed from CGPS (Continuous Global Positioning Stations) at the present day. The Cenozoic could be a good analogue for the present day and for projecting into the future.

  14. Continuity and Admixture in the Last Five Millennia of Levantine History from Ancient Canaanite and Present-Day Lebanese Genome Sequences.

    PubMed

    Haber, Marc; Doumet-Serhal, Claude; Scheib, Christiana; Xue, Yali; Danecek, Petr; Mezzavilla, Massimo; Youhanna, Sonia; Martiniano, Rui; Prado-Martinez, Javier; Szpak, Michał; Matisoo-Smith, Elizabeth; Schutkowski, Holger; Mikulski, Richard; Zalloua, Pierre; Kivisild, Toomas; Tyler-Smith, Chris

    2017-08-03

    The Canaanites inhabited the Levant region during the Bronze Age and established a culture that became influential in the Near East and beyond. However, the Canaanites, unlike most other ancient Near Easterners of this period, left few surviving textual records and thus their origin and relationship to ancient and present-day populations remain unclear. In this study, we sequenced five whole genomes from ∼3,700-year-old individuals from the city of Sidon, a major Canaanite city-state on the Eastern Mediterranean coast. We also sequenced the genomes of 99 individuals from present-day Lebanon to catalog modern Levantine genetic diversity. We find that a Bronze Age Canaanite-related ancestry was widespread in the region, shared among urban populations inhabiting the coast (Sidon) and inland populations (Jordan) who likely lived in farming societies or were pastoral nomads. This Canaanite-related ancestry derived from mixture between local Neolithic populations and eastern migrants genetically related to Chalcolithic Iranians. We estimate, using linkage-disequilibrium decay patterns, that admixture occurred 6,600-3,550 years ago, coinciding with recorded massive population movements in Mesopotamia during the mid-Holocene. We show that present-day Lebanese derive most of their ancestry from a Canaanite-related population, which therefore implies substantial genetic continuity in the Levant since at least the Bronze Age. In addition, we find Eurasian ancestry in the Lebanese not present in Bronze Age or earlier Levantines. We estimate that this Eurasian ancestry arrived in the Levant around 3,750-2,170 years ago during a period of successive conquests by distant populations. Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

  15. Technical Report Series on Global Modeling and Data Assimilation. Volume 7: Proceedings of the Workshop on the GEOS-1 Five-year Assimilation

    NASA Technical Reports Server (NTRS)

    Suarez, Max J. (Editor); Schubert, Siegfried; Rood, Richard

    1995-01-01

    The primary objective of the three-day workshop on results from the Data Assimilation Office (DAO) five-year assimilation was to provide timely feedback from the data users concerning the strengths and weaknesses of version 1 of the Goddard Earth Observing System (GEOS-1) assimilated products. A second objective was to assess user satisfaction with the current methods of data access and retrieval. There were a total of 49 presentations, with about half (23) of the presentations from scientists from outside of Goddard. The first two days were devoted to applications of data: studies of the energy diagnostics, precipitation and diabatic heating, hydrological modeling and moisture transport, cloud forcing and validation, various aspects of intraseasonal, seasonal, and interannual variability, ocean wind stress applications, and validation of surface fluxes. The last day included talks from the National Meteorological Center (NMC), the National Center for Atmospheric Research (NCAR), the Center for Ocean-Land-Atmosphere Studies (COLA), the United States Navy, and the European Center for Medium Range Weather Forecasts (ECMWF).

  16. Body Weight and Mood State Modifications in Mixed Martial Arts: An Exploratory Pilot.

    PubMed

    Brandt, Ricardo; Bevilacqua, Guilherme G; Coimbra, Danilo R; Pombo, Luiz C; Miarka, Bianca; Lane, Andrew M

    2018-06-20

    Brandt, R, Bevilacqua, GG, Coimbra, DR, Pombo, LC, Miarka, B, and Lane, AM. Body weight and mood state modifications in mixed martial arts: An exploratory pilot. J Strength Cond Res XX(X): 000-000, 2018-Mixed martial arts (MMA) fighters typically use rapid weight loss (RWL) as a strategy to make competition weight. The aim of the present study was to compare body weight and mood changes in professional male MMA athletes who used strategies to rapidly lose weight (n = 9) and with MMA athletes who did not (n = 3). Body mass and mood states of anger, confusion, depression, fatigue, tension, and vigor and total mood disturbance were assessed (a) 30 days before competition, (b) at the official weigh-in 1 day before competition, (c) 10 minutes before competition, and (d) 10 minutes postcompetition. Results indicated that RWL associated with reporting higher confusion and greater total mood disturbance at each assessment point. Rapid weight loss also associated with high anger at the official weigh-in. However, in performance, RWL did not have deleterious effects on performance. The RWL group also reported greater total mood disturbance at all assessment points with a moderate difference effect size. Research supports the notion that RWL associates with potentially dysfunctional mood states.

  17. Fatal Flea-Borne Typhus in Texas: A Retrospective Case Series, 1985-2015.

    PubMed

    Pieracci, Emily G; Evert, Nicole; Drexler, Naomi A; Mayes, Bonny; Vilcins, Inger; Huang, Philip; Campbell, Jill; Behravesh, Casey Barton; Paddock, Christopher D

    2017-05-01

    AbstractFlea-borne (murine) typhus is a global rickettsiosis caused by Rickettsia typhi . Although flea-borne typhus is no longer nationally notifiable, cases are reported for surveillance purposes in a few U.S. states. The infection is typically self-limiting, but may be severe or life-threatening in some patients. We performed a retrospective review of confirmed or probable cases of fatal flea-borne typhus reported to the Texas Department of State Health Services during 1985-2015. When available, medical charts were also examined. Eleven cases of fatal flea-borne typhus were identified. The median patient age was 62 years (range, 36-84 years) and 8 (73%) were male. Patients presented most commonly with fever (100%), nausea and vomiting (55%), and rash (55%). Respiratory (55%) and neurologic (45%) manifestations were also identified frequently. Laboratory abnormalities included thrombocytopenia (82%) and elevated hepatic transaminases (63%). Flea or animal contact before illness onset was frequently reported (55%). The median time from hospitalization to administration of a tetracycline-class drug was 4 days (range, 0-5 days). The median time from symptom onset to death was 14 days (range, 1-34 days). Flea-borne typhus can be a life-threatening disease if not treated in a timely manner with appropriate tetracycline-class antibiotics. Flea-borne typhus should be considered in febrile patients with animal or flea exposure and respiratory or neurologic symptoms of unknown etiology.

  18. 77 FR 60279 - Gold Star Mother's and Family's Day, 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-03

    ... Star Mother's and Family's Day, 2012 By the President of the United States of America A Proclamation... daughters, fathers and mothers, husbands and wives, they were all patriots--and with a devotion to duty that... Mother's Day.'' NOW, THEREFORE, I, BARACK OBAMA, President of the United States of America, by virtue of...

  19. Insight: An Annual Collection of Articles on Teaching and Learning by Faculty of the Community Colleges of the State University of New York. 1984-85.

    ERIC Educational Resources Information Center

    Burns, Charles A., Ed.

    Articles dealing with instructional approaches, faculty development, and student needs are presented. The 1984-85 collection includes: "An Evolving Partnership: The Community College-Secondary School Connection," by Cornelius V. Robbins; "What If Willy Loman Worked for You," by Paul W. Brennan; "Day Care Centers: The Versatile Student Support…

  20. Predicting the Future as Bayesian Inference: People Combine Prior Knowledge with Observations when Estimating Duration and Extent

    ERIC Educational Resources Information Center

    Griffiths, Thomas L.; Tenenbaum, Joshua B.

    2011-01-01

    Predicting the future is a basic problem that people have to solve every day and a component of planning, decision making, memory, and causal reasoning. In this article, we present 5 experiments testing a Bayesian model of predicting the duration or extent of phenomena from their current state. This Bayesian model indicates how people should…

  1. The School in Crisis, Crisis in the Memory of School. School, Democracy, and Economic Modernity in France from the Late Middle Ages to the Present Day.

    ERIC Educational Resources Information Center

    Caspard, Pierre

    1998-01-01

    Examines the educational system in France, addressing the interests and roles of the family and communals. Evaluates the roles of three major institutional actors that took part in the emergence and organization of the educational systems: (1) the Church; (2) the State; and (3) the industrial bourgeoisie. (CMK)

  2. There's a Hole in State Standards and New Teachers like Me Are Falling through

    ERIC Educational Resources Information Center

    Education Digest: Essential Readings Condensed for Quick Review, 2008

    2008-01-01

    This article presents the author's experience as a new teacher lamenting the lack of clear and achievable expectations. Given a book list in place of a curriculum on her first day, she comments that she can understand why such a lack of guidance for new teachers can lead to frustration and departures. She further shares that since becoming a…

  3. Ares I Upper Stage Update

    NASA Technical Reports Server (NTRS)

    Davis, Daniel J.

    2010-01-01

    These presentation slides review the progress in the development of the Ares I upper stage. The development includes development of a manufacturing and processing assembly that will reduce the time required over 100 days, development of a weld tool that is a robotic tool that is the largest welder of its kind in the United States, development of avionics and software, and development of logisitics and operations systems.

  4. [Current problems in the laboratory control of louse-borne typhus infection in Ukraine].

    PubMed

    Klymchuk, M D

    1996-01-01

    Surveys designed to study spread of typhus infection (persistent form and Brill's disease), and state of laboratory diagnosis in Ukraine showed an important role the laboratory diagnosis plays in the system of epidemiological surveillance aimed at preventing epidemic typhus. Main trends of activities on perfection of the system of laboratory control of the infection under present-day conditions are outlined.

  5. A Comparative Analysis of the Education Systems in Korea and Japan from the Perspective of Internationalization

    ERIC Educational Resources Information Center

    Krechetnikov, K. G.; Pestereva, N. M.

    2017-01-01

    The object of this study is the characteristics of the development of the present-day national education systems in two leading economies of the Asia-Pacific region (APR), Japan and the Republic of Korea (Korea). Its main purpose is a comparative analysis of the aspect of the state's education policy dealing with enhancing the national markets for…

  6. A Knowledge-Based Arrangement of Prototypical Neural Representation Prior to Experience Contributes to Selectivity in Upcoming Knowledge Acquisition.

    PubMed

    Kurashige, Hiroki; Yamashita, Yuichi; Hanakawa, Takashi; Honda, Manabu

    2018-01-01

    Knowledge acquisition is a process in which one actively selects a piece of information from the environment and assimilates it with prior knowledge. However, little is known about the neural mechanism underlying selectivity in knowledge acquisition. Here we executed a 2-day human experiment to investigate the involvement of characteristic spontaneous activity resembling a so-called "preplay" in selectivity in sentence comprehension, an instance of knowledge acquisition. On day 1, we presented 10 sentences (prior sentences) that were difficult to understand on their own. On the following day, we first measured the resting-state functional magnetic resonance imaging (fMRI). Then, we administered a sentence comprehension task using 20 new sentences (posterior sentences). The posterior sentences were also difficult to understand on their own, but some could be associated with prior sentences to facilitate their understanding. Next, we measured the posterior sentence-induced fMRI to identify the neural representation. From the resting-state fMRI, we extracted the appearances of activity patterns similar to the neural representations for posterior sentences. Importantly, the resting-state fMRI was measured before giving the posterior sentences, and thus such appearances could be considered as preplay-like or prototypical neural representations. We compared the intensities of such appearances with the understanding of posterior sentences. This gave a positive correlation between these two variables, but only if posterior sentences were associated with prior sentences. Additional analysis showed the contribution of the entorhinal cortex, rather than the hippocampus, to the correlation. The present study suggests that prior knowledge-based arrangement of neural activity before an experience contributes to the active selection of information to be learned. Such arrangement prior to an experience resembles preplay activity observed in the rodent brain. In terms of knowledge acquisition, the present study leads to a new view of the brain (or more precisely of the brain's knowledge) as an autopoietic system in which the brain (or knowledge) selects what it should learn by itself, arranges preplay-like activity as a position for the new information in advance, and actively reorganizes itself.

  7. A Knowledge-Based Arrangement of Prototypical Neural Representation Prior to Experience Contributes to Selectivity in Upcoming Knowledge Acquisition

    PubMed Central

    Kurashige, Hiroki; Yamashita, Yuichi; Hanakawa, Takashi; Honda, Manabu

    2018-01-01

    Knowledge acquisition is a process in which one actively selects a piece of information from the environment and assimilates it with prior knowledge. However, little is known about the neural mechanism underlying selectivity in knowledge acquisition. Here we executed a 2-day human experiment to investigate the involvement of characteristic spontaneous activity resembling a so-called “preplay” in selectivity in sentence comprehension, an instance of knowledge acquisition. On day 1, we presented 10 sentences (prior sentences) that were difficult to understand on their own. On the following day, we first measured the resting-state functional magnetic resonance imaging (fMRI). Then, we administered a sentence comprehension task using 20 new sentences (posterior sentences). The posterior sentences were also difficult to understand on their own, but some could be associated with prior sentences to facilitate their understanding. Next, we measured the posterior sentence-induced fMRI to identify the neural representation. From the resting-state fMRI, we extracted the appearances of activity patterns similar to the neural representations for posterior sentences. Importantly, the resting-state fMRI was measured before giving the posterior sentences, and thus such appearances could be considered as preplay-like or prototypical neural representations. We compared the intensities of such appearances with the understanding of posterior sentences. This gave a positive correlation between these two variables, but only if posterior sentences were associated with prior sentences. Additional analysis showed the contribution of the entorhinal cortex, rather than the hippocampus, to the correlation. The present study suggests that prior knowledge-based arrangement of neural activity before an experience contributes to the active selection of information to be learned. Such arrangement prior to an experience resembles preplay activity observed in the rodent brain. In terms of knowledge acquisition, the present study leads to a new view of the brain (or more precisely of the brain’s knowledge) as an autopoietic system in which the brain (or knowledge) selects what it should learn by itself, arranges preplay-like activity as a position for the new information in advance, and actively reorganizes itself. PMID:29662446

  8. 42 CFR 457.203 - Administrative and judicial review of action on State plan material.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... determines that his or her original decision was incorrect, CMS will pay the State a lump sum equal to any... with the Administrator's action on State plan material under § 457.150 may, within 60 days after... of hearing. Within 30 days after receipt of the request, the Administrator notifies the State of the...

  9. Clinical characteristics and outcome of management of Fournier's gangrene at the Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria.

    PubMed

    Omisanjo, Olufunmilade A; Bioku, M J; Ikuerowo, S O; Sule, G A; Esho, J O

    2014-01-01

    Fournier's gangrene (FG) though a rare condition can be associated with significant mortality. There are few reports in our environment documenting the outcome of management of the condition. The aim of the following study was to describe the clinical characteristics and outcome of management of patients with FG in a tertiary hospital in Southwest Nigeria. The clinical records of patients who presented with FG at a tertriary hospital over a 5 year period were reviewed. A total of 11 cases were reviewed and all patients were male. The scrotum alone was the most common site of involvement (54.5%). Late presentation was common with 9.6 days (range 1-21 days) being the average duration between the onset of symptoms and presentation at the hospital. Most of the patients (63.6%) did not have any identifiable systemic predisposing factor. There was no mortality or testicular loss recorded. Patients with FG still present late in our environment. However, appropriate aggressive treatment can help ameliorate the associated mortality and morbidity even in a resource poor setting.

  10. Present-day dynamics and future evolution of the world's northernmost ice cap, Hans Tausen Iskappe (Greenland)

    NASA Astrophysics Data System (ADS)

    Zekollari, Harry; Huybrechts, Philippe; Noël, Brice; van de Berg, Willem Jan; van den Broeke, Michiel R.

    2017-04-01

    In this study the dynamics of Hans Tausen Iskappe (western Peary Land, Greenland) are investigated with a coupled ice flow - mass balance model. Precipitation is obtained from the Regional Climate Model RACMO 2.3 and the surface mass balance is calculated from a Positive Degree-Day runoff/retention model, for which the input parameters are derived from field observations. For the ice flow a 3-D higher-order thermo-mechanical model is used, which is run at a 250 m resolution. Under 1961-1990 climatic conditions a steady state ice cap is obtained that is overall similar in geometry to the present-day ice cap. Ice thickness, temperature and flow velocity in the interior agree well with observations. For the outlet glaciers a reasonable agreement with temperature and ice thickness measurements can only be obtained with an additional heat source related to infiltrating meltwater. The simulations indicate that the SMB-elevation feedback has a major effect on the ice cap response time and stability. This causes the southern part of the ice cap to be extremely sensitive to a change in climatic conditions and leads to thresholds in the ice cap evolution. Under constant 2005-2014 climatic conditions the entire southern part of the ice cap cannot be sustained and the ice cap loses about 80% of its present-day volume. The future projected loss of surrounding permanent sea-ice and corresponding potential sharp precipitation increase may however lead to an attenuation of the retreat and even potential stabilization of the ice cap for a warming of up to 2-3°C. In a warmer and wetter climate the ice margin will retreat while the interior is projected to grow, leading to a steeper ice cap, in line with the present-day observed trends. For intermediate (+4°C) and high warming scenarios (+8°C) the ice cap is projected to disappear respectively around 2400 and 2200 A.D., almost irrespective of the projected precipitation regime and the simulated present-day geometry.

  11. Sensitivity, stability and future evolution of the world's northernmost ice cap, Hans Tausen Iskappe (Greenland)

    NASA Astrophysics Data System (ADS)

    Zekollari, Harry; Huybrechts, Philippe; Noël, Brice; van de Berg, Willem Jan; van den Broeke, Michiel R.

    2017-03-01

    In this study the dynamics and sensitivity of Hans Tausen Iskappe (western Peary Land, Greenland) to climatic forcing is investigated with a coupled ice flow-mass balance model. The surface mass balance (SMB) is calculated from a precipitation field obtained from the Regional Atmospheric Climate Model (RACMO2.3), while runoff is calculated from a positive-degree-day runoff-retention model. For the ice flow a 3-D higher-order thermomechanical model is used, which is run at a 250 m resolution. A higher-order solution is needed to accurately represent the ice flow in the outlet glaciers. Under 1961-1990 climatic conditions a steady-state ice cap is obtained that is overall similar in geometry to the present-day ice cap. Ice thickness, temperature and flow velocity in the interior agree well with observations. For the outlet glaciers a reasonable agreement with temperature and ice thickness measurements can be obtained with an additional heat source related to infiltrating meltwater. The simulations indicate that the SMB-elevation feedback has a major effect on the ice cap response time and stability. This causes the southern part of the ice cap to be extremely sensitive to a change in climatic conditions and leads to thresholds in the ice cap evolution. Under constant 2005-2014 climatic conditions the entire southern part of the ice cap cannot be sustained, and the ice cap loses about 80 % of its present-day volume. The projected loss of surrounding permanent sea ice and resultant precipitation increase may attenuate the future mass loss but will be insufficient to preserve the present-day ice cap for most scenarios. In a warmer and wetter climate the ice margin will retreat, while the interior is projected to thicken, leading to a steeper ice cap, in line with the present-day observed trends. For intermediate- (+4 °C) and high- warming scenarios (+8 °C) the ice cap is projected to disappear around AD 2400 and 2200 respectively, almost independent of the projected precipitation regime and the simulated present-day geometry.

  12. 20th Aerospace Mechanisms Symposium. Revised

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The proceedings of the 20th Aerospace Mechanisms Symposium, hosted by the NASA Lewis Research Center, Cleveland, Ohio, on May 7-9, 1986, is documented herein. During the 3 days, 23 technical papers were presented by experts from the United States and Western Europe. A panel discussion by an International group of experts on future directions In mechanisms was also presented; this discussion, however, is not documented herein. The technical topics addressed included deployable structures, electromagnetic devices, tribology, thermal/mechanical/hydraulic actuators, latching devices, positioning mechanisms, robotic manipulators, and computerized mechanisms synthesis.

  13. Manufacturing of diamond windows for synchrotron radiation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schildkamp, W.; Nikitina, L.

    2012-09-15

    A new diamond window construction is presented and explicit manufacturing details are given. This window will increase the power dissipation by about a factor of 4 over present day state of the art windows to absorb 600 W of power. This power will be generated by in-vacuum undulators with the storage ring ALBA operating at a design current of 400 mA. Extensive finite element (FE) calculations are included to predict the windows behavior accompanied by explanations for the chosen boundary conditions. A simple linear model was used to cross-check the FE calculations.

  14. [Effect of extremely low frequency magnetic field on glutathione in rat muscles].

    PubMed

    Ciejka, Elzbieta; Jakubowska, Ewa; Zelechowska, Paulina; Huk-Kolega, Halina; Kowalczyk, Agata; Goraca, Anna

    2014-01-01

    Free radicals (FR) are atoms, molecules or their fragments. Their excess leads to the development of oxidizing stress, the cause of many neoplastic, neurodegenerative and inflammatory diseases, and aging of the organism. Industrial pollution, tobacco smoke, ionizing radiation, ultrasound and magnetic field are the major FR exogenous sources. The low frequency magnetic field is still more commonly applied in the physical therapy. The aim of the presented study was to evaluate the effect of extremely low frequency magnetic field used in the magnetotherapy on the level of total glutathione, oxidized and reduced, and the redox state of the skeletal muscle cells, depending on the duration of exposure to magnetic field. The male rats, weight of 280-300 g, were randomly devided into 3 experimental groups: controls (group I) and treatment groups exposed to extremely low frequency magnetic field (ELF-MF) (group II exposed to 40 Hz, 7 mT for 0.5 h/day for 14 days and group III exposed to 40 Hz, 7 mT for 1 h/day for 14 days). Control rats were kept in a separate room not exposed to extremely low frequency magnetic field. Immediately after the last exposure, part of muscles was taken under pentobarbital anesthesia. Total glutathione, oxidized and reduced, and the redox state in the muscle tissue of animals were determined after exposure to magnetic fields. Exposure to low magnetic field: 40 Hz, 7 mT for 30 min/day and 60 min/day for 2 weeks significantly increased the total glutathione levels in the skeletal muscle compared to the control group (p < 0.001). Exposure to magnetic fields used in the magnetic therapy plays an important role in the development of adaptive mechanisms responsible for maintaining the oxidation-reduction balance in the body and depends on exposure duration.

  15. 77 FR 14854 - 30-Day Notice of Proposed Information Collection: Department of State Acquisition Regulation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-13

    ... DEPARTMENT OF STATE [Public Notice: 7823] 30-Day Notice of Proposed Information Collection... for public comment and submission to OMB of proposed collection of information. SUMMARY: The Department of State has submitted the following information collection request to the Office of Management...

  16. 75 FR 77041 - 60-Day Notice of Proposed Information Collections: Two Information Collections

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-10

    ... directed to Nicholas Memos, Office of Defense Trade Controls Policy, Department of State, who may be..., Directorate of Defense Trade Controls, Bureau of Political-Military Affairs, U.S. Department of State... DEPARTMENT OF STATE [Public Notice: 7251] 60-Day Notice of Proposed Information Collections: Two...

  17. 77 FR 37729 - 30-Day Notice of Proposed Information Collections: DDTC Brokering Collections

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-22

    ... Director of Defense Trade Controls, Bureau of Political- Military Affairs, U.S. Department of State. [FR... DEPARTMENT OF STATE [Public Notice 7929] 30-Day Notice of Proposed Information Collections: DDTC... collections of information. SUMMARY: The Department of State has submitted the following information...

  18. 78 FR 27469 - 30-Day Notice of Proposed Information Collection: Evacuee Manifest and Promissory Note

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ... DEPARTMENT OF STATE [Public Notice 8316] 30-Day Notice of Proposed Information Collection: Evacuee... collection of information. SUMMARY: The Department of State has submitted the information collection... the Department of State Desk Officer in the Office of Information and Regulatory Affairs at the Office...

  19. State and district policy influences on district-wide elementary and middle school physical education practices.

    PubMed

    Chriqui, Jamie F; Eyler, Amy; Carnoske, Cheryl; Slater, Sandy

    2013-01-01

    To examine the influence of state laws and district policies on district-wide elementary school and middle school practices related to physical education (PE) time and the percentage of moderate-to-vigorous physical activity (MVPA) time during PE. Multivariate, cross-sectional analysis of state laws, district wellness and PE policies, and district PE practices for school year 2010-2011 controlling for district-level urbanicity, region, size, race/ethnicity of students, and socioeconomic status and clustered on state. One hundred ninety-five public school districts located in 42 states. District-level PE coordinators for the included districts who responded to an online survey. Minutes and days of PE per week and percent time spent in MVPA during PE time. District PE coordinators reported significantly less PE time than national standards-82.9 and 189.6 minutes at the elementary school and middle school levels, respectively. Physical education was provided an average of 2.5 and 3.7 days per week, respectively; and the percentage of MVPA time in PE was 64.4% and 65.7%, respectively. At the elementary school level, districts in either states with laws governing PE time or in a state and district with a law/policy reported significantly more days of PE (0.63 and 0.67 additional days, respectively), and districts in states with PE time laws reported 18 more minutes of PE per week. At the middle school level, state laws were associated with 0.73 more days of PE per week. Neither state laws nor district policies were positively associated with percent MVPA time in PE. State laws and district policies can influence district-level PE practices-particularly those governing the frequency and duration of PE-although opportunities exist to strengthen PE-related laws, policies, and practices.

  20. Present-day heat flow model of Mars

    PubMed Central

    Parro, Laura M.; Jiménez-Díaz, Alberto; Mansilla, Federico; Ruiz, Javier

    2017-01-01

    Until the acquisition of in-situ measurements, the study of the present-day heat flow of Mars must rely on indirect methods, mainly based on the relation between the thermal state of the lithosphere and its mechanical strength, or on theoretical models of internal evolution. Here, we present a first-order global model for the present-day surface heat flow for Mars, based on the radiogenic heat production of the crust and mantle, on scaling of heat flow variations arising from crustal thickness and topography variations, and on the heat flow derived from the effective elastic thickness of the lithosphere beneath the North Polar Region. Our preferred model finds heat flows varying between 14 and 25 mW m−2, with an average value of 19 mW m−2. Similar results (although about ten percent higher) are obtained if we use heat flow based on the lithospheric strength of the South Polar Region. Moreover, expressing our results in terms of the Urey ratio (the ratio between total internal heat production and total heat loss through the surface), we estimate values close to 0.7–0.75, which indicates a moderate contribution of secular cooling to the heat flow of Mars (consistent with the low heat flow values deduced from lithosphere strength), unless heat-producing elements abundances for Mars are subchondritic. PMID:28367996

  1. Using present day observations to detect when ocean acidification exceeds natural variability of surface seawater Ωaragonite

    NASA Astrophysics Data System (ADS)

    Sutton, A.; Sabine, C. L.; Feely, R. A.

    2016-02-01

    One of the major challenges to assessing the impact of ocean acidification on marine life is the need to better understand the magnitude of long-term change in the context of natural variability. High-frequency moored observations can be highly effective in defining interannual, seasonal, and subseasonal variability at key locations. Here we present monthly aragonite saturation state (Ωaragonite) climatology for 15 open ocean, coastal, and coral reef locations using 3-hourly moored observations of surface seawater pCO2 and pH collected together since as early as 2009. We then use these present day surface mooring observations to estimate pre-industrial variability at each location and compare these results to previous modeling studies addressing global-scale variability and change. Our observations suggest that open oceans sites, especially in the subtropics, are experiencing Ωaragonite values throughout much of the year which are outside the range of pre-industrial values. In coastal and coral reef ecosystems, which have higher natural variability, seasonal patterns where present day Ωaragonite values exceeding pre-industrial bounds are emerging with some sites exhibiting subseasonal conditions approaching Ωaragonite = 1. Linking these seasonal patterns in carbonate chemistry to biological processes in these regions is critical to identify when and where marine life may encounter Ωaragonite values outside the conditions to which they have adapted.

  2. Timeliness in the German surveillance system for infectious diseases: Amendment of the infection protection act in 2013 decreased local reporting time to 1 day

    PubMed Central

    Diercke, Michaela; Salmon, Maëlle; Czogiel, Irina; Schumacher, Dirk; Claus, Hermann; Gilsdorf, Andreas

    2017-01-01

    Time needed to report surveillance data within the public health service delays public health actions. The amendment to the infection protection act (IfSG) from 29 March 2013 requires local and state public health agencies to report surveillance data within one working day instead of one week. We analysed factors associated with reporting time and evaluated the IfSG amendment. Local reporting time is the time between date of notification and date of export to the state public health agency and state reporting time is time between date of arrival at the state public health agency and the date of export. We selected cases reported between 28 March 2012 and 28 March 2014. We calculated the median local and state reporting time, stratified by potentially influential factors, computed a negative binominal regression model and assessed quality and workload parameters. Before the IfSG amendment the median local reporting time was 4 days and 1 day afterwards. The state reporting time was 0 days before and after. Influential factors are the individual local public health agency, the notified disease, the notification software and the day of the week. Data quality and workload parameters did not change. The IfSG amendment has decreased local reporting time, no relevant loss of data quality or identifiable workload-increase could be detected. State reporting time is negligible. We recommend efforts to harmonise practices of local public health agencies including the exclusive use of software with fully compatible interfaces. PMID:29088243

  3. Kinetics of rabies antibodies as a strategy for canine active immunization

    PubMed Central

    2014-01-01

    Background Rabies, a zoonosis found throughout the globe, is caused by a virus of the Lyssavirus genus. The disease is transmitted to humans through the inoculation of the virus present in the saliva of infected mammals. Since its prognosis is usually fatal for humans, nationwide public campaigns to vaccinate dogs and cats against rabies aim to break the epidemiological link between the virus and its reservoirs in Brazil. Findings During 12 months we evaluated the active immunity of dogs first vaccinated (booster shot at 30 days after first vaccination) against rabies using the Fuenzalida-Palácios modified vaccine in the urban area of Botucatu city, São Pauto state, Brazil. Of the analyzed dogs, 54.7% maintained protective titers (≥0.5 IU/mL) for 360 days after the first vaccination whereas 51.5% during all the study period. Conclusions The present results suggest a new vaccination schedule for dogs that have never been vaccinated. In addition to the first dose of vaccine, two others are recommended: the second at 30 days after the first and the third dose at 180 days after the first for the maintenance of protective titers during 12 months. PMID:26413082

  4. Calcitriol Prevents Cardiovascular Repercussions in Puromycin Aminonucleoside-Induced Nephrotic Syndrome

    PubMed Central

    Roberto, Roncon-Albuquerque

    2018-01-01

    Puromycin aminonucleoside-induced nephrotic syndrome (PAN-NS) is characterized by cardiac remodeling and increased local inflammatory activity. Patients with NS and animal models of NS have vitamin D3 deficiency. The aim of the present study was to evaluate the influence of calcitriol on cardiac remodeling and local inflammatory state in PAN-NS rat model. Male Sprague-Dawley rats were injected with PAN or vehicle on day 0. PAN and control rats were divided into two subgroups for the administration of calcitriol (PAN-D and Ct-D groups) or the vehicle (PAN-V and Ct-V groups) during 21 days. On day 21, the renal function, metabolic balance, calcitriol and FGF-23 plasma levels, prohypertrophy and proinflammatory markers (ET-1, TGF-β1, TNF-α, and IL-1β), and calcium signaling molecules (PLB and SERCA-2a) were evaluated. Twenty-one days after injection, PAN-V group presented cardiac hypertrophy and a modulation of proinflammatory markers local expression. Calcitriol treatment of PAN rats prevented cardiac hypertrophy and was associated with marked reduction in the cardiac expression levels of proinflammatory markers. Our results suggest that vitamin D3 deficiency in PAN-NS may contribute to cardiac remodeling and to the increase in local inflammatory activity. Calcitriol treatment prevents both cardiac repercussions and local inflammatory processes in PAN-NS. PMID:29607318

  5. The role of self-esteem instability in the development of postnatal depression: A prospective study testing a diathesis-stress account.

    PubMed

    Franck, Erik; Vanderhasselt, Marie-Anne; Goubert, Liesbet; Loeys, Tom; Temmerman, Marleen; De Raedt, Rudi

    2016-03-01

    Understanding vulnerability factors involved in the development of postnatal depression has important implications for theory and practice. In this prospective study, we investigated whether self-esteem instability during pregnancy would better predict postnatal depressive symptomatology than level of self-esteem. In addition, going beyond former studies, we tested the possible origin of this instability, examining whether day-to-day fluctuations in self-esteem could be explained by fluctuations in mood state, and whether this day-to-day self-esteem reactivity would predict postnatal depressive symptoms. 114 healthy never-depressed women were tested during the late second or third trimester of their gestation (Time 1) and at 12 weeks after delivery (Time 2). Day-to-day levels of self-esteem and depressed mood state were assessed at Time 1. At Time 2, postnatal depressive symptoms were assessed. The results show that, after controlling for initial depressive symptomatology, age and socio-economic status, postnatal depressive symptomatology at 12 weeks after childbirth could be predicted by self-esteem instability and not level of self-esteem. In addition, multi-level analyses demonstrated that these changes in day-to-day levels of self-esteem are associated with changes in day-to-day levels of depressed mood state and that those subjects with greater prenatal self-esteem reactivity upon depressed mood report higher levels of depressive symptoms post-partum. We used paper and pencil day-to-day measures of state self-esteem, which can be subject to bias. These results provide evidence for a diathesis-stress account of postnatal depression, highlighting the importance of a multi-dimensional view of self-esteem and the predictive role of self-esteem instability. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ulrike Thoma

    The possibility that gluonic excitations of hadronic matter or of the QCD vacuum may exist is perhaps one of the most fascinating topics in hadron spectroscopy. Glueballs are predicted by many models; in particular present-day lattice gauge calculations require their existence. All these models agree that the lightest glueball should have scalar quantum numbers and a mass around 1.6 GeV, which corresponds to the mass region where the scalar qq[bar]-mesons are expected. Therefore mixing effects can complicate the search for the glueball. Experiments indeed show an overpopulation of states, for which many different interpretations exist. This reflects the complexity ofmore » the situation. New data from various experiments on scalar states give hints toward an interpretation of the scalar states. But, still many questions remain.« less

  7. New perspectives on evolutionary medicine: the relevance of microevolution for human health and disease

    PubMed Central

    2013-01-01

    Evolutionary medicine (EM) is a growing field focusing on the evolutionary basis of human diseases and their changes through time. To date, the majority of EM studies have used pure theories of hominin macroevolution to explain the present-day state of human health. Here, we propose a different approach by addressing more empirical and health-oriented research concerning past, current and future microevolutionary changes of human structure, functions and pathologies. Studying generation-to-generation changes of human morphology that occurred in historical times, and still occur in present-day populations under the forces of evolution, helps to explain medical conditions and warns clinicians that their current practices may influence future humans. Also, analyzing historic tissue specimens such as mummies is crucial in order to address the molecular evolution of pathogens, of the human genome, and their coadaptations. PMID:23627943

  8. 3 CFR 9055 - Proclamation 9055 of November 5, 2013. Veterans Day, 2013

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... marking the 60th anniversary of the Korean War Armistice, we resolved that in the United States of America... 3 The President 1 2014-01-01 2014-01-01 false Proclamation 9055 of November 5, 2013. Veterans Day... Proc. 9055 Veterans Day, 2013By the President of the United States of America A Proclamation On...

  9. Overview of the Human Exploration Research Analog (HERA)

    NASA Technical Reports Server (NTRS)

    Neigut, J.

    2015-01-01

    In 2013, the Human Research Program at NASA began developing a new confinement analog specifically for conducting research to investigate the effects of confinement on the human system. The HERA (Human Exploration Research Analog) habitat has been used for both 7 and 14 day missions to date to examine and mitigate exploration risks to enable safe, reliable and productive human space exploration. This presentation will describe how the Flight Analogs Project developed the HERA facility and the infrastructure to suit investigator requirements for confinement research and in the process developed a new approach to analog utilization and a new state of the art analog facility. Details regarding HERA operations will be discussed including specifics on the mission simulation utilized for the current 14-day campaign, the specifics of the facility (total volume, overall size, hardware), and the capabilities available to researchers. The overall operational philosophy, mission fidelity including timeline, schedule pressures and cadence, and development and implementation of mission stressors will be presented. Research conducted to date in the HERA has addressed risks associated with behavioral health and performance, human physiology, as well as human factors. This presentation will conclude with a discussion of future research plans for the HERA, including infrastructure improvements and additional research capabilities planned for the upcoming 30-day missions in 2016.

  10. Coadministration of voriconazole and phenytoin: pharmacokinetic interaction, safety, and toleration

    PubMed Central

    Purkins, Lynn; Wood, Nolan; Ghahramani, Parviz; Love, Edward R; Eve, Malcolm D; Fielding, Anitra

    2003-01-01

    Aims Voriconazole is a new triazole antifungal agent, and is metabolized by the cytochrome P450 isoenzymes CYP2C9, CYP2C19, and, to a lesser extent, by CYP3A4. Phenytoin is an inducer of CYP3A4 activity, and a substrate and inducer of CYP2C9 and CYP2C19. The present studies investigated the pharmacokinetic interactions of voriconazole and phenytoin when coadministered. Methods Two placebo-controlled parallel-group studies were conducted in healthy male volunteers. Study A was an open-label study and investigated the effect of phenytoin (300 mg once daily) on the steady-state pharmacokinetics of voriconazole (200 mg and 400 mg twice daily). Study B was a double-blind randomized study to investigate the effects of voriconazole (400 mg twice daily) on the steady-state pharmacokinetics of phenytoin (300 mg once daily). Cmax and AUCτ were compared at days 7, 21, and 28 (Study A), and at days 7 and 17 (Study B). All adverse events were recorded. Results Study A: 21 subjects were evaluable (10 voriconazole + phenytoin, 11 voriconazole + placebo). For subjects receiving voriconazole (200 mg twice daily) plus phenytoin, the day 21/day 7 ratios for voriconazole Cmax and AUCτ were 60.7% [90% confidence interval (CI) 50.1, 73.6] and 35.9% (90% CI 29.7, 43.3), respectively. Adjusted for voriconazole + placebo, the ratios between the means were 50.7% (90% CI 38.8, 66.1) and 30.6% (90% CI 23.5, 39.7), respectively. When the dose of voriconazole was increased to 400 mg twice daily, the day 28/day 7 ratios for voriconazole Cmax and AUCτ were 134% (90% CI 89.2, 200) and 139% (90% CI 97.3, 199), respectively. Study B: 15 subjects were evaluable for pharmacokinetic assessments (six phenytoin + voriconazole, nine phenytoin + placebo). The ratios between the means for phenytoin + voriconazole/phenytoin + placebo on day 17 vs. day 7 were: phenytoin Cmax 167% (90% CI 144, 193) and phenytoin AUCτ 181% (90% CI 156, 210). All treatments were well tolerated: most adverse events were mild/moderate and transient. Conclusions Repeat dose administration of phenytoin decreased the mean steady-state Cmax and AUCτ of voriconazole by approximately 50% and 70%, respectively. Increasing the dose of voriconazole from 200 mg to 400 mg b.d. compensated for this effect. Repeat dose administration of 400 mg b.d. voriconazole increased the mean steady-state Cmax and AUCτ of phenytoin by approximately 70% and 80%, respectively. It is therefore recommended that plasma phenytoin concentrations are monitored and the dose adjusted as appropriate when phenytoin is coadministered with voriconazole. PMID:14616412

  11. Recent Efforts to Improve the Near Real Time Forest Disturbance Monitoring Capabilities of the ForWarn System

    NASA Technical Reports Server (NTRS)

    Spruce, Joseph; Hargrove, William; Gasser, Gerald

    2013-01-01

    This presentation discusses the development of anew method for computing NDVI temporal composites from near real time eMODIS data This research is being conducted to improve forest change products used in the ForWarn system for monitoring regional forest disturbances in the United States. ForWarn provides nation-wide NDVI-based forest disturbance detection products that are refreshed every 8 days. Current eMODIS and historical MOD13 24 day NDVI data are used to compute the disturbance detection products. The eMODIS 24 day NDVI data re-aggregated from 7 day NDVI products. The 24 day eMODIS NDVIs are generally cloud free, but do not necessarily use the freshest quality data. To shorten the disturbance detection time, a method has been developed that performs adaptive length/maximum value compositing of eMODIS NDVI, along with cloud and shadow "noise" mitigation. Tests indicate that this method can reduce detection rates by 8-16 days for known recent disturbance events, depending on the cloud frequencies and disturbance type. The noise mitigation in these tests, though imperfect, helped to improve quality of the resulting NDVI and forest change products.

  12. Effects of tryptophan depletion on selective serotonin reuptake inhibitor-remitted patients with obsessive compulsive disorder.

    PubMed

    Hood, Sean D; Broyd, Annabel; Robinson, Hayley; Lee, Jessica; Hudaib, Abdul-Rahman; Hince, Dana A

    2017-12-01

    Serotonergic antidepressants are first-line medication therapies for obsessive-compulsive disorder, however it is not known if synaptic serotonin availability is important for selective serotonin reuptake inhibitor efficacy. The present study tested the hypothesis that temporary reduction in central serotonin transmission, through acute tryptophan depletion, would result in an increase in anxiety in selective serotonin reuptake inhibitor-remitted obsessive-compulsive disorder patients. Eight patients (four males) with obsessive-compulsive disorder who showed sustained clinical improvement with selective serotonin reuptake inhibitor treatment underwent acute tryptophan depletion in a randomized, double-blind, placebo-controlled, within-subjects design, over two days one week apart. Five hours after consumption of the depleting/sham drink the participants performed a personalized obsessive-compulsive disorder symptom exposure task. Psychological responses were measured using the Spielberger State Anxiety Inventory, Yale-Brown Obsessive Compulsive Scale and Visual Analogue Scales. Free plasma tryptophan to large neutral amino acid ratio decreased by 93% on the depletion day and decreased by 1% on the sham day, as anticipated. Psychological rating scores as measured by Visual Analogue Scale showed a significant decrease in perceived control and increase in interfering thoughts at the time of provocation on the depletion day but not on the sham day. A measure of convergent validity, namely Visual Analogue Scale Similar to past, was significantly higher at the time of provocation on both the depletion and sham days. Both the depletion and time of provocation scores for Visual Analogue Scale Anxiety, Spielberger State Anxiety Inventory, Yale-Brown Obsessive Compulsive Scale and blood pressure were not significant. Acute tryptophan depletion caused a significant decrease in perceived control and increase in interfering thoughts at the time of provocation. Acute tryptophan depletion had no effect on the Spielberger State Anxiety Inventory or Visual Analogue Scale Anxiety measures, which suggests that the mechanism of action of selective serotonin reuptake inhibitors may be different to that seen in panic, social anxiety and post-traumatic stress disorder. Successful selective serotonin reuptake inhibitor treatment of obsessive-compulsive disorder may involve the ability of serotonin to switch habitual responding to goal-directed behaviour.

  13. Neural Predictors of Visuomotor Adaptation Rate and Multi-Day Savings

    NASA Technical Reports Server (NTRS)

    Cassady, Kaitlin; Ruitenberg, Marit; Koppelmans, Vincent; Reuter-Lorenz, Patricia; De Dios, Yiri; Gadd, Nichole; Wood, Scott; Riascos Castenada, Roy; Kofman, Igor; Bloomberg, Jacob; hide

    2017-01-01

    Recent studies of sensorimotor adaptation have found that individual differences in task-based functional brain activation are associated with the rate of adaptation and savings at subsequent sessions. However, few studies to date have investigated offline neural predictors of adaptation and multi-day savings. In the present study, we explore whether individual differences in the rate of visuomotor adaptation and multi-day savings are associated with differences in resting state functional connectivity and gray matter volume. Thirty-four participants performed a manual adaptation task during two separate test sessions, on average 9 days apart. We found that resting state functional connectivity strength between sensorimotor, anterior cingulate, and temporoparietal areas of the brain was a significant predictor of adaptation rate during the early, cognitive phase of practice. In contrast, default mode network functional connectivity strength was found to predict late adaptation rate and savings on day two, which suggests that these behaviors may rely on overlapping processes. We also found that gray matter volume in temporoparietal and occipital regions was a significant predictor of early learning, whereas gray matter volume in superior posterior regions of the cerebellum was a significant predictor of late adaptation. The results from this study suggest that offline neural predictors of early adaptation facilitate the cognitive mechanisms of sensorimotor adaptation, with support from by the involvement of temporoparietal and cingulate networks. In contrast, the neural predictors of late adaptation and savings, including the default mode network and the cerebellum, likely support the storage and modification of newly acquired sensorimotor representations. These findings provide novel insights into the neural processes associated with individual differences in sensorimotor adaptation.

  14. Effects of a spaceflight analog environment on brain connectivity and behavior.

    PubMed

    Cassady, Kaitlin; Koppelmans, Vincent; Reuter-Lorenz, Patricia; De Dios, Yiri; Gadd, Nichole; Wood, Scott; Castenada, Roy Riascos; Kofman, Igor; Bloomberg, Jacob; Mulavara, Ajitkumar; Seidler, Rachael

    2016-11-01

    Sensorimotor functioning is adaptively altered following long-duration spaceflight. The question of whether microgravity affects other central nervous system functions such as brain network organization and its relationship with behavior is largely unknown, but of importance to the health and performance of astronauts both during and post-flight. In the present study, we investigate the effects of prolonged exposure to an established spaceflight analog on resting state brain functional connectivity and its association with behavioral changes in 17 male participants. These bed rest participants remained in bed with their heads tilted down six degrees below their feet for 70 consecutive days. Resting state functional magnetic resonance imaging (rs-fMRI) and behavioral data were obtained at seven time points averaging around: 12 and 8days prior to bed rest; 7, 50, and 70days during bed rest; and 8 and 12days after bed rest. To assess potential confounding effects due to scanning interval or task practice, we also acquired rs-fMRI and behavioral measurements from 14 control participants at four time points. 70days of head-down tilt (HDT) bed rest resulted in significant changes in the functional connectivity of motor, somatosensory, and vestibular areas of the brain. Moreover, several of these network alterations were significantly associated with changes in sensorimotor and spatial working memory performance, which suggests that neuroplasticity mechanisms may facilitate adaptation to the microgravity analog environment. The findings from this study provide novel insights into the underlying neural mechanisms and operational risks of spaceflight analog-related changes in sensorimotor performance. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Investigations of 2β decay of {sup 106}Cd and {sup 58}Ni with HPGe spectrometer OBELIX

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rukhadze, E.; Fajt, L.; Hodák, R.

    2015-08-17

    Investigations of double beta decay processes to excited states of daughter nuclei were performed at the Modane underground laboratory (LSM, France, 4800 m w.e.) using the high sensitivity spectrometer OBELIX [1], which is a common activity of JINR Dubna, IEAP CTU in Prague and LSM. The spectrometer is based on the HPGe detector with the sensitive volume of 600 cm{sup 3} and relative efficiency of 160%. Investigation of resonant neutrino-less double electron capture of {sup 106}Cd was performed with ∼23.2 g of {sup 106}Cd (enrichment of 99.57%) during ∼17 days. The experiment with natural Ni (∼21.7 kg of mass) was also carried out duringmore » ∼47 days. The preliminary experimental limits for 0νEC/EC resonant decay to the excited states of {sup 106}Pd and different modes of β β decay {sup 58}Ni are presented.« less

  16. Evidence of Tropospheric 90 Day Oscillations in the Thermosphere

    NASA Astrophysics Data System (ADS)

    Gasperini, F.; Hagan, M. E.; Zhao, Y.

    2017-10-01

    In the last decade evidence demonstrated that terrestrial weather greatly impacts the dynamics and mean state of the thermosphere via small-scale gravity waves and global-scale solar tidal propagation and dissipation effects. While observations have shown significant intraseasonal variability in the upper mesospheric mean winds, relatively little is known about this variability at satellite altitudes (˜250-400 km). Using cross-track wind measurements from the Challenging Minisatellite Payload and Gravity field and steady-state Ocean Circulation Explorer satellites, winds from a Modern-Era Retrospective Analysis for Research and Applications/Thermosphere-Ionosphere-Mesosphere-Electrodynamics General Circulation Model simulation, and outgoing longwave radiation data, we demonstrate the existence of a prominent and global-scale 90 day oscillation in the thermospheric zonal mean winds and in the diurnal eastward propagating tide with zonal wave number 3 (DE3) during 2009-2010 and present evidence of its connection to variability in tropospheric convective activity. This study suggests that strong coupling between the troposphere and the thermosphere occurs on intraseasonal timescales.

  17. Long-Term Spectral and Timing Behavior of the Black Hole Candidate XTE J1908+094

    NASA Technical Reports Server (NTRS)

    Gogus, Ersin; Finger, Mark H.; Kouveliotou, Chryssa; Woods, Peter M.; Patel, Sandeep K.; Ruppen, Michael; Swank, Jean H.; Markwardt, Craig B.; VanDerKlis, Michiel

    2004-01-01

    We present the long-term X-ray light curves and detailed spectral and timing analyses of XTE J1908+094 using the Rossi X-Ray Timing Explorer Proportional Counter Array observations covering two outbursts in 2002 and early 2003. At the onset of the first outburst, the source was found in a spectrally low/hard state lasting for approx.40 days, followed by a 3 day long transition to the high/soft state. The source flux (in 2- 10 keV) reached approx.100 mcrab on 2002 April 6, then decayed rapidly. In power spectra, we detect strong band-limited noise and varying low- frequency quasi-periodic oscillations that evolved from approx.0.5 to approx.5 Hz during the initial low/hard state of the source. We find that the second outburst closely resembled the spectral evolution of the first. The X-ray transient s overall outburst characteristics led us to classify XTE J1908+094 as a black hole candidate. Here we also derive precise X-ray position of the source using Chandra observations that were performed during the decay phase of the first outburst and following the second outburst.

  18. Progressive Derechos in the Presence of Closed Upper-level Subtropical Anticyclones

    NASA Astrophysics Data System (ADS)

    Guastini, C.; Bosart, L. F.

    2013-12-01

    Progressive derechos are a type of long-lived mesoscale convective system that produces large swaths of wind damage. In contrast to their serial derecho counterparts, which form in association with extratropical cyclones, progressive derechos often occur in the presence of benign synoptic conditions on the poleward side of closed upper-level subtropical anticyclones. Forecasters have been known to struggle predicting progressive derechos with any certainty due to the common lack of large-scale support for severe weather in regimes dominated by anticyclonic conditions. This study will classify a group of days on which there was a closed upper-level anticyclone over the United States and a progressive derecho did not occur and a group of days on which there was a closed upper-level anticyclone over the United States and a progressive derecho did occur, examine the synoptic environments of the two groups, and identify derecho null cases. By analyzing the null cases, derecho failure modes will be determined, which will help forecaster situational awareness and reveal the science behind the environmental conditions necessary for, and detrimental to, derecho development. This presentation will include climatologies of both derechos and closed upper-level anticyclones over the United States for June, July, and August of the years 1994-2013 (the modern radar era). The presentation will also include closed anticyclone-relative composites of both derecho cases and derecho null cases. The composites will elucidate which conditions are necessary for, and which are detrimental to, derecho development. The hypothesis is that derecho failure days occur due either to the lack of a triggering mechanism or other phenomena working against convective development such as a strong capping inversion or transverse ageostrophic circulations around an upper-level jet creating subsidence in an otherwise favorable environment. A representative case study will be included to highlight a common derecho failure mode.

  19. Hypothyroidism and oxidative stress: differential effect on the heart of virgin and pregnant rats.

    PubMed

    Carmona, Y V; Coria, M J; Oliveros, L B; Gimenez, M S

    2014-01-01

    The present study investigates the effects of hypothyroidism on both the redox state and the thyroid hormone receptors expression in the heart ventricle of virgin and pregnant rats.Hypothyroid state was induced by 6-n-propyl-2-thiouracil in drinking water given to Wistar rats starting 8 days before mating until day 21 of pregnancy or for 30 days in virgin rats. Serum paraoxonase-1 (PON-1) activity, serum and heart nitrites, and thiobarbituric acid-reactive substances (TBARS) were analyzed. Heart protein oxidation, as carbonyls, and copper-zinc superoxide dismutase (CuZnSOD), glutathione peroxidase (GPx), and catalase (CAT) activities, were determined. In addition, heart expressions of NADPH oxidase (NOX-2), CAT, SOD, GPx, and thyroid receptors (TRα and TRβ) mRNA were assessed by RT-PCR. Inducible and endothelial Nitric Oxide Synthase (iNOS and eNOS) were determined by Western blot. Hypothyroidism in the heart of virgin rats decreased TRα and TRβ expressions, and induced oxidative stress, leading to a decrease of nitrites and an increase of carbonyls, NOX-2 mRNA, and GPx activity. A decreased PON-1 activity suggested low protection against oxidative stress in blood circulation. Pregnancy reduced TRα and TRβ mRNA expressions and induced oxidative stress by increasing nitrite and TBARS levels, SOD and CAT activities and NOX-2, eNOS and iNOS expressions, while hypothyroidism, emphasized the decreases of TRα mRNA levels and did not alter the redox state in the heart. TR expressions and redox balance of rat hearts depend on the physiological state. Pregnancy per se seems to protect the heart against oxidative stress induced by hypothyroidism. Supporting Information for this article is available online at http://www.thieme-connect.de/ejournals/toc/hmr. © Georg Thieme Verlag KG Stuttgart · New York.

  20. The mediating role of state maladaptive emotion regulation in the relation between social anxiety symptoms and self-evaluation bias.

    PubMed

    Sarfan, Laurel D; Cody, Meghan W; Clerkin, Elise M

    2018-03-16

    Although social anxiety symptoms are robustly linked to biased self-evaluations across time, the mechanisms of this relation remain unclear. The present study tested three maladaptive emotion regulation strategies - state post-event processing, state experiential avoidance, and state expressive suppression - as potential mediators of this relation. Undergraduate participants (N = 88; 61.4% Female) rated their social skill in an impromptu conversation task and then returned to the laboratory approximately two days later to evaluate their social skill in the conversation again. Consistent with expectations, state post-event processing and state experiential avoidance mediated the relation between social anxiety symptoms and worsening self-evaluations of social skill (controlling for research assistant evaluations), particularly for positive qualities (e.g. appeared confident, demonstrated social skill). State expressive suppression did not mediate the relation between social anxiety symptoms and changes in self-evaluation bias across time. These findings highlight the role that spontaneous, state experiential avoidance and state post-event processing may play in the relation between social anxiety symptoms and worsening self-evaluation biases of social skill across time.

  1. VLF Radio Wave Propagation Across the Day/Night Terminator

    NASA Astrophysics Data System (ADS)

    Burch, H.; Moore, R. C.

    2016-12-01

    In May 2016, a new array of VLF radio receivers was deployed spanning the East Coast of the United States. We present preliminary observations from the array, which was designed in part to track the propagation of the narrowband VLF transmitter signal, NAA (24.0 kHz), down the coast from Cutler, Maine. Amplitude, phase, and polarization observations are compared over multiple days and at different times of year to investigate the dependence of VLF propagation characteristics on solar zenith angle. Measurements are compared to simulations using the Long Wave Propagation Capability code (LWPC) in order to evaluate the accuracy of LWPC's built-in ionosphere model. Efforts to improve the ionosphere model based on observations are discussed.

  2. Health Impacts of Yoga and Pranayama: A State-of-the-Art Review

    PubMed Central

    Sengupta, Pallav

    2012-01-01

    Thousands of years ago yoga originated in India, and in present day and age, an alarming awareness was observed in health and natural remedies among people by yoga and pranayama which has been proven an effective method for improving health in addition to prevention and management of diseases. With increasing scientific research in yoga, its therapeutic aspects are also being explored. Yoga is reported to reduce stress and anxiety, improves autonomic functions by triggering neurohormonal mechanisms by the suppression of sympathetic activity, and even, now-a-days, several reports suggested yoga is beneficial for physical health of cancer patients. Such global recognition of yoga also testifies to India's growing cultural influence. PMID:22891145

  3. The Role of the United States in a Changing World. A Curriculum Unit on Foreign Policy Choices.

    ERIC Educational Resources Information Center

    Brown Univ., Providence, RI. Center for Foreign Policy Development.

    This 3- to 5-day currriculum unit for secondary students centers around four possible directions for U.S. foreign policy during the 1990s. Designed as a culminating exercise at the end of the year or as an introductory activity to open the semester, this unit, and the possible futures it presents, should be thought of as a vehicle for guiding…

  4. Guantanamo Detention Facility - Why is it Still There

    DTIC Science & Technology

    2012-03-22

    the detainees, dressed in orange jumpsuits, kneeling on the ground, being held in “ dog kennels ” - a perception that to this day is still seen by...President of the United States to use all necessary and appropriate force against those nations, organizations, or persons he determines planned ...incorporated in the design . Camp 5 is handicap accessible for detainees with physical disabilities.25 Legality of Detention Detainees presently being held

  5. Medical Department, United States Army. Surgery in World War II. Neurosurgery. Volume 1

    DTIC Science & Technology

    1958-01-01

    116 Photomicrograph showing petechial hemorrhages in cortex ------------------- 378 117 Photomicrograph showing nerve cell changes in caudate nucleus...headache unrelieved by ordinary medication or when there were signs of increasing intracranial hypertension; and (4) diagnosis of persistent fever ...hemorrhage at various points along the track of the bullet, was almost. invariably present for some days, or even for weeks, after injury. Fever was also

  6. Some conclusions from the registration of electrophonic bolides tracks in the "Unified Churyumov Network" in 2013-2017

    NASA Astrophysics Data System (ADS)

    Steklov, A. F.; Kruchynenko, V. G.; Vidmachenko, A. P.; Dashkiev, G. N.; Steklov, E. A.

    2017-09-01

    The review of main results of observations of traces for day and twilight invasion of electrophone bolides into the atmosphere over Kiev and the region in 2013-2017 is presented. The panicle fly away of numerous flocks of birds from area of the fall of electrophone bolide was observed. Observers themselves were also in a state of unexplained anxiety and discomfort.

  7. Mobile radio alternative systems study, executive summary

    NASA Technical Reports Server (NTRS)

    Anderson, R. E.; Cromwell, N.; Lester, H. L.

    1983-01-01

    Present day mobile communication technologies, systems and equipment are described from background in evaluating the concepts generated in the study. Average propagation ranges are calculated for terrestrial installations in each of seven physiographic areas of the contiguous states to determine the number of installations that would be required for nationwide coverage. Four system concepts are defined and analyzed to determine how well terrestrial systems can fulfill the requirements at acceptable costs.

  8. The Arts & Government: Questions for the Nineties. Report of the American Assembly Conference (Harriman, New York, November 8-11, 1990).

    ERIC Educational Resources Information Center

    American Assembly, New York, NY.

    The proceedings of a 3-day conference, discussing the relationship between government and the arts in the United States, are presented. Issues that will confront the arts in the 1990s were identified and policy recommendations were suggested. Six basic principles were reflected in many of the discussions: (1) a flourishing artistic life is in the…

  9. Prescription for Progress? A Commentary on the Education Policy of the World Bank. Studies in Education (New Series) 3.

    ERIC Educational Resources Information Center

    Williams, Peter, Ed.

    This booklet summarizes the proceedings of a one-day seminar on the educational policy of the World Bank and presents six papers prepared for the seminar. The seminar was held at the University of London Institute of Education in May 1975 and focused mainly on the World Bank's policy on educational aid as stated in its 1974 "Education Sector…

  10. Noncontact Temperature Measurement

    NASA Technical Reports Server (NTRS)

    Lee, Mark C. (Editor)

    1988-01-01

    Noncontact temperature measurement has been identified as one of the eight advanced technology development (ATD) areas to support the effort of the Microgravity Science and Applications Division in developing six Space Station flight experiment facilities. This two-day workshop was an opportunity for all six disciplines to present their requirements on noncontact temperature measurement and to discuss state-of-the-art developments. Multi-color pyrometry, laser pyrometry and radiometric imaging techniques are addressed.

  11. The French School System and the Universalist Metanarrative (1880-2000s): Some Reflections about So-Called Explanatory Historical Notions Such as "La Forme Scolaire"

    ERIC Educational Resources Information Center

    Robert, Andre D.

    2013-01-01

    This article aims to question the relevance of notions such as "laforme scolair"' in the account of the French state action in keeping up with the development of mass schooling, over a long historical process (from the late nineteenth century to the present day). Through its origin, this model is linked to a Universalist philosophical…

  12. Reasserting the Relevance of the Social Studies: An Emerging Model for Collaborative Cross-State Research

    ERIC Educational Resources Information Center

    Passe, Jeff; Patterson, Nancy

    2011-01-01

    There is a timely movement afoot to secure the rightful place of social studies as a core part of curriculum at a time when it is increasingly compromised across the nation. The authors present a model that accepts the call to consider the enterprise of social studies research and broaden it to address the needs of the day. They offer a brief…

  13. Improving Performance Of Industrial Enterprises With CGT

    NASA Astrophysics Data System (ADS)

    Dolgih, I. N.; Bannova, K. A.; Kuzmina, N. A.; Zdanova, A. B.

    2016-04-01

    At the present day, a falling in the overall level of efficiency production activities, especially in the machine-building companies makes it necessary to development various actions in the State support, including through the creation consolidated taxation system. Such support will help improve efficiency of activity not only the industrial companies, but also will allow improve economic and social situation in regions where often large engineering factories is city-forming.

  14. Unsupported inferences of high-severity fire in historical dry forests of the western United States: Response to Williams and Baker

    Treesearch

    Peter Z. Fule; Thomas W. Swetnam; Peter M. Brown; Donald A. Falk; David L. Peterson; Craig D. Allen; Gregory H. Aplet; Mike A. Battaglia; Dan Binkley; Calvin Farris; Robert E. Keane; Ellis Q. Margolis; Henri Grissino-Mayer; Carol Miller; Carolyn Hull Sieg; Carl Skinner; Scott L. Stephens; Alan Taylor

    2014-01-01

    Reconstructions of dry western US forests in the late 19th century in Arizona, Colorado and Oregon based on General Land Office records were used by Williams & Baker (2012; Global Ecology and Biogeography, 21, 1042-1052; hereafter W&B) to infer past fire regimes with substantial moderate and high-severity burning. The authors concluded that present-day large,...

  15. Charters, Constitutions and By-Laws of Indian Tribes of North America. Part I: The Sioux Tribes of South Dakota. Occasional Publications in Anthropology, Ethnology Series, No. 1.

    ERIC Educational Resources Information Center

    Fay, George E., Comp.

    To facilitate the study and understanding of present-day Indian tribal organization and governmental procedures, the Museum of Anthropology of the University of Northern Colorado (formerly known as Colorado State College) has assembled a large number of Indian tribal charters, constitutions, and by-laws to be reproduced as a series of…

  16. A Prospective Investigation of Affect, the Desire to Gamble, Gambling Motivations and Gambling Behavior in the Mood Disorders.

    PubMed

    Quilty, Lena C; Watson, Chris; Toneatto, Tony; Bagby, R Michael

    2017-03-01

    Time-sampling methodology was implemented to examine the prospective associations between affect, desire to gamble, and gambling behavior in individuals diagnosed with a mood disorder. Thirty (9 male, 21 female) adults with a lifetime diagnosis of a depressive or bipolar disorder diagnosis who endorsed current gambling and lifetime gambling harm participated in the present study. Participants completed electronic diary entries of their current affective state, desire to gamble, and gambling behavior for 30 consecutive days. Hierarchical linear modelling revealed that affect was not a predictor of gambling behavior. Instead, affect predicted the desire to gamble, with high levels of sadness and arousal independently predicting an increased desire to gamble. Desire to gamble predicted actual gambling behavior. There were no differences across diagnostic groups in terms of gambling motivations at baseline; however, during the 30-day period, participants with bipolar disorder endorsed gambling to cope with negative affect more often than did participants with depressive disorder, whereas those with depressive disorder more often endorsed gambling for social reasons or enhancement of positive affect. The present findings provide evidence that negative affect is not directly related to actual gambling behavior, and suggest that affective states rather impact the desire to gamble.

  17. 77 FR 70693 - Approval and Promulgation of State Implementation Plans; State of New Mexico; Regional Haze Rule...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-27

    ... Backstop Sulfur Dioxide Trading Program, for the inventorying of emissions, for smoke management, and open... make an appointment. If possible, please make the appointment at least two working days in advance of... percent worst days in 2018 and no degradation in visibility conditions on the 20 percent best days at all...

  18. Water-Rock Differentiation on Ceres as Derived From Numerical Studies: Late Water Separation and Thick Undifferentiated Crust

    NASA Astrophysics Data System (ADS)

    Neumann, Wladimir Otto; Breuer, Doris; Spohn, Tilman

    2016-10-01

    Water-rock separation is a major factor in discriminating between models of Ceres' present-day state. We calculate differentiation models of Ceres to investigate how water-rock separation and convection influence its evolution. We expand on the presence of liquids and the possibility of cryovolcanism in order to explain surface features observed by Dawn[1,2].The model[3] includes accretion, reduction of the dust porosity, latent heat of ice melting, compaction driven water-rock separation, accretional heating, hydrothermal circulation, solid-state convection of ice, and convection in a water ocean.Accretion times considered cover 1-10 Ma rel. to CAIs. Compaction of the dust pores starts with ice at T≈180-240 K and proceeds with rock minerals at temperatures of up to 730 K. Sub-surface remains too cold to close these pores. The water-rock separation proceeds by water percolation in a rock matrix. Differentiation timing depends on the matrix deformation and no differentiation occurs in layers with leftover dust porosity. Compaction takes several hundred million years due to a slow temperature increase. The differentiation is extended according to this time scale even though liquid water is produced early. While the radionuclides are concentrated in the core no heat is produced in the ocean. If convection is neglected, the ocean is heated by the core and cooled through the crust, and remains totally liquid until the present day. Convection keeps the ocean cold and results in a colder present-day crust. Only a thin basal part of the ocean remains liquid, while the upper part freezes.In our models, a water ocean starts forming within 10 Ma after CAIs, but its completion is retarded relative to the melting of ice by up to O(0.1 Ga). The differentiation is partial and a porous outer layer is retained. Present-day temperatures calculated indicate that hydrated salts can be mobile at a depth of ≥1.5-5 km implying buoyancy of ice and salt-enriched crustal reservoirs. The impacts Haulani, Ikapati and Occator may have cut into these reservoirs triggering the mobility that formed cryovolcanic features[1,2].[1] Jaumann R et al. (2016) LPSC XLVII [2] Krohn K et al. (2016) LPSC XLVII. [3] Neumann W et al. (2015) A&A 584: A117.

  19. Car indoor air pollution - analysis of potential sources

    PubMed Central

    2011-01-01

    The population of industrialized countries such as the United States or of countries from the European Union spends approximately more than one hour each day in vehicles. In this respect, numerous studies have so far addressed outdoor air pollution that arises from traffic. By contrast, only little is known about indoor air quality in vehicles and influences by non-vehicle sources. Therefore the present article aims to summarize recent studies that address i.e. particulate matter exposure. It can be stated that although there is a large amount of data present for outdoor air pollution, research in the area of indoor air quality in vehicles is still limited. Especially, knowledge on non-vehicular sources is missing. In this respect, an understanding of the effects and interactions of i.e. tobacco smoke under realistic automobile conditions should be achieved in future. PMID:22177291

  20. Performing under pressure: Exploring the psychological state underlying clutch performance in sport.

    PubMed

    Swann, Christian; Crust, Lee; Jackman, Patricia; Vella, Stewart A; Allen, Mark S; Keegan, Richard

    2017-12-01

    Clutch performance is improved performance under pressure. However, little research has examined the psychological state experienced by athletes in these situations. Therefore, this study qualitatively examined the subjective experience underlying clutch performance across a range of sports (e.g., team, individual) and standards (Olympic to recreational athletes). Sixteen athletes (M age  = 27.08 years; SD = 6.48) took part in in-depth, semi-structured interviews primarily after an exceptional performance (M = 4.38 days later; SD = 3.14). Data were analysed inductively and thematically. Clutch states involved 12 characteristics, including heightened and deliberate concentration, intense effort, and heightened awareness, which distinguished the experience of clutch from other optimal psychological states such as flow. Other characteristics, such as perceptions of control, were also reported and supported previous experimental research on clutch. These findings present in-depth qualitative insights into the psychological state underlying clutch performance, and are discussed in relation to the existing literature on optimal psychological states in sport.

  1. Coma and vegetative states: state of the art and proposal of a novel approach combining existing coma scales.

    PubMed

    Bonsignore, Luca Tommaso; Macrì, Simone; Orsi, Paolo; Chiarotti, Flavia; Alleva, Enrico

    2014-01-01

    Brain damage of various aetiologies can lead to different disorders of consciousness (DOC), varying from coma to vegetative, to minimally conscious states. Each state is characterised by a different degree of wakefulness, awareness, pain sensitivity and is differentially handled with respect to treatment, ethical considerations and end-oflife decisions. Thus, its correct identification is crucial while devising or modulating appropriate treatment strategies. Actually, the main coma scales cannot always accurately determine the state of consciousness of an individual, while other tools (e.g. imaging techniques) present a certain degree of uncertainty. A complementary approach may be constituted by a 24-hour observation of patients, for a sufficient period of days, using an ad hoc behavioural scale, further correlated with physiological and pharmacological parameters measured on patients. The method herein described might help recognising the presence of consciousness of the different DOC patients, and thus discerning a vegetative from a minimally conscious state.

  2. Cosmological implications of quantum mechanics parametrization of dark energy

    NASA Astrophysics Data System (ADS)

    Szydłowski, Marek; Stachowski, Aleksander; Urbanowski, Krzysztof

    2017-08-01

    We consider the cosmology with the running dark energy. The parametrization of dark energy is derived from the quantum process of transition from the false vacuum state to the true vacuum state. This model is the generalized interacting CDM model. We consider the energy density of dark energy parametrization, which is given by the Breit-Wigner energy distribution function. The idea of the process of the quantum mechanical decay of unstable states was formulated by Krauss and Dent. We used this idea in our considerations. In this model is an energy transfer in the dark sector. In this evolutional scenario the universe starts from the false vacuum state and goes to the true vacuum state of the present day universe. The intermediate regime during the passage from false to true vacuum states takes place. In this way the cosmological constant problem can be tried to solve. We estimate the cosmological parameters for this model. This model is in a good agreement with the astronomical data and is practically indistinguishable from CDM model.

  3. Exclusion of overlapping symptoms in DSM-5 mixed features specifier: heuristic diagnostic and treatment implications.

    PubMed

    Malhi, Gin S; Byrow, Yulisha; Outhred, Tim; Fritz, Kristina

    2017-04-01

    This article focuses on the controversial decision to exclude the overlapping symptoms of distractibility, irritability, and psychomotor agitation (DIP) with the introduction of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) mixed features specifier. In order to understand the placement of mixed states within the current classification system, we first review the evolution of mixed states. Then, using Kraepelin's original classification of mixed states, we compare and contrast his conceptualization with modern day definitions. The DSM-5 workgroup excluded DIP symptoms, arguing that they lack the ability to differentiate between manic and depressive states; however, accumulating evidence suggests that DIP symptoms may be core features of mixed states. We suggest a return to a Kraepelinian approach to classification-with mood, ideation, and activity as key axes-and reintegration of DIP symptoms as features that are expressed across presentations. An inclusive definition of mixed states is urgently needed to resolve confusion in clinical practice and to redirect future research efforts.

  4. Coupling MODIS images and agrometeorological data for agricultural water productivity analyses in the Mato Grosso State, Brazil

    NASA Astrophysics Data System (ADS)

    de C. Teixeira, Antônio H.; Victoria, Daniel C.; Andrade, Ricardo G.; Leivas, Janice F.; Bolfe, Edson L.; Cruz, Caroline R.

    2014-10-01

    Mato Grosso state, Central West Brazil, has been highlighted by the grain production, mainly soybean and corn, as first (November-March) and second (April-August) harvest crops, respectively. For water productivity (WP) analyses, MODIS products together with a net of weather stations were used. Evapotranspiration (ET) and biomass production (BIO) were acquired during the year 2012 and WP was considered as the ratio of BIO to ET. The SAFER (Simple Algorithm For Evapotranspiration Retrieving) for ET and the Monteith's radiation model for BIO were applied together, considering a mask which separated the crops from other surface types. In relation to the first harvest crop ET, BIO and WP values above of those for other surface types, happened only from November to January with incremental values reaching to 1.2 mm day-1; 67 kg ha-1 day-1; and 0.7 kg m-3, respectively; and between March and May for the second harvest crops, with incremental values attaining 0.5 mm day-1; 27 kg ha-1 day-1; and 0.3 kg m-3, respectively. In both cases, during the growing seasons, the highest WP parameters in cropped areas corresponded, in general, to the blooming to grain filling transition. Considering corn crop, which nowadays is increasing in terms of cultivated areas in the Brazilian Central West region, and crop water productivity (CWP) the ratio of yield to the amount of water consumed, the main growing regions North, Southeast and Northeast were analyzed. Southeast presented the highest annual pixel averages for ET, BIO and CWP (1.7 mm day-1, 78 kg ha-1 day-1 and 2.2 kg m-3, respectively); while for Northeast they were the lowest ones (1.2 mm day-1, 52 kg ha-1 dia-1 and 1.9 kg m-3). Throughout a soil moisture indicator, the ratio of precipitation (P) to ET, it was indeed noted that rainfall was enough for a good grain yield, with P/ET lower than 1.00 only outside the crop growing seasons. The combination of MODIS images and weather stations proved to be useful for monitoring vegetation and water parameters, which can contribute to the sustainability of the agro-ecosystems exploration in Mato Grosso state, avoiding water scarcity in the near future.

  5. 76 FR 5236 - 60-Day Notice of Proposed Information Collection: Form DS-4071, Export Declaration of Defense...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... Nicholas Memos, Office of Defense Trade Controls Policy, Department of State, who may be reached via the... Director of Defense Trade Controls, Bureau of Political- Military Affairs, U.S. Department of State. [FR... DEPARTMENT OF STATE [Public Notice: 7315] 60-Day Notice of Proposed Information Collection: Form...

  6. 9 CFR 93.423 - Ruminants from Central America and the West Indies.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... they were directly shipped to the United States for a period of at least 60 days immediately preceding... from the British Virgin Islands into the United States Virgin Islands, for immediate slaughter, only... be within 14 days after the date of entry into the United States Virgin Islands; and if they are...

  7. Patterns of drug use in fatal crashes.

    PubMed

    Romano, Eduardo; Pollini, Robin A

    2013-08-01

    To characterize drug prevalence among fatally injured drivers, identify significant associations (i.e. day of week, time of day, age, gender), and compare findings with those for alcohol. Descriptive and logistic mixed-model regression analyses of Fatality Analysis Reporting System data. US states with drug test results for >80% of fatally injured drivers, 1998-2010. Drivers killed in single-vehicle crashes on public roads who died at the scene of the crash (n = 16 942). Drug test results, blood alcohol concentration (BAC), gender, age and day and time of crash. Overall, 45.1% of fatally injured drivers tested positive for alcohol (39.9% BAC ≥ 0.08) and 25.9% for drugs. The most common drugs present were stimulants (7.2%) and cannabinols (7.1%), followed by 'other' drugs (4.1%), multiple drugs (4.1%), narcotics (2.1%) and depressants (1.5%). Drug-involved crashes occurred with relative uniformity throughout the day while alcohol-involved crashes were more common at night (P < 0.01). The odds of testing positive for drugs varied depending upon drug class, driver characteristics, time of day and the presence of alcohol. Fatal single-vehicle crashes involving drugs are less common than those involving alcohol and the characteristics of drug-involved crashes differ, depending upon drug class and whether alcohol is present. Concerns about drug-impaired driving should not detract from the current law enforcement focus on alcohol-impaired driving. © 2013 Society for the Study of Addiction.

  8. Early-onset Lyme carditis with concurrent disseminated erythema migrans.

    PubMed

    Patel, Kinjan P; Farjo, Peter D; Juskowich, Joy J; Hama Amin, Ali; Mills, James D

    2017-01-01

    Lyme disease is an infection that is estimated to affect over 300,000 people in the United States annually. Typically, it presents with erythema migrans (EM), an annular rash at the site of tick attachment, within 3 to 30 days of inoculation. Untreated patients may progress to early disseminated disease. A further complication, Lyme carditis is rare but may occur several weeks later. It commonly manifests as a variable atrioventricular (AV) conduction block, with a high-grade AV block occurring in only 1% of untreated patients. This case demonstrates an unusually early presentation of Lyme carditis with complete heart block. A 21-year-old male was transferred from an outside emergency department (ED) for possible pacemaker placement due to symptomatic third-degree AV block. Four days earlier the patient presented to the outside ED with fever, chills, and unrecognized EM on his right neck. He was discharged with antipyretics, but no antibiotic therapy. On the day of transfer, he returned with persistent fevers, EM now on his trunk and upper extremities, lightheadedness, and substernal chest pressure. An electrocardiogram revealed the third-degree AV block leading to transfer. Upon arrival, the patient was promptly diagnosed with Lyme carditis. Pacemaker implantation was deferred, and intravenous (IV) ceftriaxone was initiated. Within 48 hours his third-degree AV block improved to a first-degree block. By this time, his EM had also resolved. He was discharged with oral doxycycline and a 30-day event monitor, which ultimately showed persistent first-degree AV block. This case reinforces a unique presentation of Lyme carditis. Disseminated EM and Lyme carditis may present concurrently within 2 weeks of tick attachment. Early recognition and treatment is important for preventing progression to disseminated infection. Lyme-associated AV block will reverse within 48 to 72 hours of initiating IV antibiotic therapy and will not require pacemaker implantation. Lyme carditis should be considered in patients without heart disease who present with any degree of AV block.

  9. Do contrails significantly reduce daily temperature range?

    NASA Astrophysics Data System (ADS)

    Hong, Gang; Yang, Ping; Minnis, Patrick; Hu, Yong X.; North, Gerald

    2008-12-01

    One of the most visible anthropogenic phenomena in the atmosphere is the occurrence of contrails. The direct effects of contrails on surface temperature are investigated on the basis of the data sets for the cloud cover and surface temperature over the conterminous United States for the period 1971-2001. It is shown that the increase of the average daily temperature range (DTR) over the United States during the three-day grounding period of 11-14 September 2001 cannot be attributed to the absence of contrails, a subject was debated in several previous studies. The present analysis suggests that the DTR is attributed to the change of low cloudiness.

  10. Rehabilitation of the Handicapped Programs, 1976. Hearings before the Subcommittee on the Handicapped of the Committee on Labor and Public Welfare, United States Senate, Ninety-Fourth Congress, Second Session on Oversight Hearings on Rehabilitation of the Handicapped Programs and the Implementation of Same by Agencies under the Rehabilitation Act of 1973. Part 1. February 20, 23, 24, 26; March 30, 1976.

    ERIC Educational Resources Information Center

    1976

    The full texts of all prepared statements and supplemental materials presented during five days of oversight hearings held on rehabilitation of the handicapped programs and implementation of these programs by agencies under the Rehabilitation Act of 1973 are contained in this document. Statements are made by (1) State and local directors and other…

  11. Using present-day observations to detect when anthropogenic change forces surface ocean carbonate chemistry outside preindustrial bounds

    NASA Astrophysics Data System (ADS)

    Sutton, Adrienne J.; Sabine, Christopher L.; Feely, Richard A.; Cai, Wei-Jun; Cronin, Meghan F.; McPhaden, Michael J.; Morell, Julio M.; Newton, Jan A.; Noh, Jae-Hoon; Ólafsdóttir, Sólveig R.; Salisbury, Joseph E.; Send, Uwe; Vandemark, Douglas C.; Weller, Robert A.

    2016-09-01

    One of the major challenges to assessing the impact of ocean acidification on marine life is detecting and interpreting long-term change in the context of natural variability. This study addresses this need through a global synthesis of monthly pH and aragonite saturation state (Ωarag) climatologies for 12 open ocean, coastal, and coral reef locations using 3-hourly moored observations of surface seawater partial pressure of CO2 and pH collected together since as early as 2010. Mooring observations suggest open ocean subtropical and subarctic sites experience present-day surface pH and Ωarag conditions outside the bounds of preindustrial variability throughout most, if not all, of the year. In general, coastal mooring sites experience more natural variability and thus, more overlap with preindustrial conditions; however, present-day Ωarag conditions surpass biologically relevant thresholds associated with ocean acidification impacts on Mytilus californianus (Ωarag < 1.8) and Crassostrea gigas (Ωarag < 2.0) larvae in the California Current Ecosystem (CCE) and Mya arenaria larvae in the Gulf of Maine (Ωarag < 1.6). At the most variable mooring locations in coastal systems of the CCE, subseasonal conditions approached Ωarag = 1. Global and regional models and data syntheses of ship-based observations tended to underestimate seasonal variability compared to mooring observations. Efforts such as this to characterize all patterns of pH and Ωarag variability and change at key locations are fundamental to assessing present-day biological impacts of ocean acidification, further improving experimental design to interrogate organism response under real-world conditions, and improving predictive models and vulnerability assessments seeking to quantify the broader impacts of ocean acidification.

  12. Test results of six-month test of two water electrolysis systems

    NASA Technical Reports Server (NTRS)

    Mills, E. S.; Wells, G. W.

    1972-01-01

    The two water electrolysis systems used in the NASA space station simulation 90-day manned test of a regenerative life support system were refurbished as required and subjected to 26-weeks of testing. The two electrolysis units are both promising systems for oxygen and hydrogen generation and both needed extensive long-term testing to evaluate the performance of the respective cell design and provide guidance for further development. Testing was conducted to evaluate performance in terms of current, pressure, variable oxygen demands, and orbital simulation. An automatic monitoring system was used to record, monitor and printout performance data at one minute, ten minute or one-hour intervals. Performance data is presented for each day of system operation for each module used during the day. Failures are analyzed, remedial action taken to eliminate problems is discussed and recommendations for redesign for future space applications are stated.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Randall T. Cygan

    “Enchanted Clays: 44th Annual Meeting of the Clay Minerals Society” was held in early June 2007 in beautiful and historic Santa Fe, New Mexico, USA. Santa Fe provided an idyllic location in the southwestern United States for the attendees to enjoy technical and social sessions while soaking up the diverse culture and wonderful climate of New Mexico—The Land of Enchantment. The meeting included a large and varied group of scientists, sharing knowledge and ideas, benefitting from technical interactions, and enjoying the wonderful historic and enchanted environs of Santa Fe. Including significant number of international scientists, the meeting was attended bymore » approximately two hundred participants. The meeting included three days of technical sessions (oral and poster presentations), three days of field trips to clay and geological sites of northern New Mexico, and a full day workshop on the stabilization of carbon by clays. Details can be found at the meeting web site: www.sandia.gov/clay.« less

  14. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Palmintier, Bryan S; Bugbee, Bruce; Gotseff, Peter

    Capturing technical and economic impacts of solar photovoltaics (PV) and other distributed energy resources (DERs) on electric distribution systems can require high-time resolution (e.g. 1 minute), long-duration (e.g. 1 year) simulations. However, such simulations can be computationally prohibitive, particularly when including complex control schemes in quasi-steady-state time series (QSTS) simulation. Various approaches have been used in the literature to down select representative time segments (e.g. days), but typically these are best suited for lower time resolutions or consider only a single data stream (e.g. PV production) for selection. We present a statistical approach that combines stratified sampling and bootstrapping tomore » select representative days while also providing a simple method to reassemble annual results. We describe the approach in the context of a recent study with a utility partner. This approach enables much faster QSTS analysis by simulating only a subset of days, while maintaining accurate annual estimates.« less

  15. The black soldier-fly, Hermetia illucens (Diptera, Stratiomyidae), used to estimate the postmortem interval in a case in Amapá State, Brazil.

    PubMed

    Pujol-Luz, José R; Francez, Pablo Abdon da Costa; Ururahy-Rodrigues, Alexandre; Constantino, Reginaldo

    2008-03-01

    The black soldier-fly (Hermetia illucens) is a generalist detritivore which is commonly present in corpses in later stages of decomposition and may be useful in forensic entomology. This paper describes the estimation of the postmortem interval (PMI) based on the life cycle of the black soldier-fly in a case in northern Brazil. A male child was abducted from his home and 42 days later his corpse was found in an advanced stage of decay. Two black soldier-fly larvae were found associated with the body. The larvae emerged as adults after 25-26 days. Considering the development cycle of H. illucens, the date of oviposition was estimated as 24-25 days after abduction. Since H. illucens usually (but not always) colonizes corpses in more advanced stages of decay, this estimate is consistent with the hypothesis that the child was killed immediately after abduction.

  16. Administration of serotonin inhibitor p-Chlorophenylalanine induces pessimistic-like judgement bias in sheep.

    PubMed

    Doyle, Rebecca E; Hinch, Geoff N; Fisher, Andrew D; Boissy, Alain; Henshall, John M; Lee, Caroline

    2011-02-01

    Judgement bias has potential as a measure of affective state in animals. The serotonergic system may be one mechanism involved with the formation of negative judgement biases. It was hypothesised that depletion of brain serotonin would induce negative judgement biases in sheep. A dose response trial established that 40 mg/kg of p-Chlorophenylalanine (pCPA) administered to sheep for 3 days did not affect feeding motivation or locomotion required for testing judgement biases. Thirty Merino ewes (10 months old) were trained to an operant task for 3 weeks. Sheep learnt to approach a bucket when it was placed in one corner of the testing facility to receive a feed reward (go response), and not approach it when in the alternate corner (no-go response) to avoid a negative reinforcer (exposure to a dog). Following training, 15 sheep were treated with pCPA (40 mg/kg daily) for an extended duration (5 days). Treated and control sheep were tested for judgement bias following 3 and 5 days of treatment, and again 5 days after cessation of treatment. Testing involved the bucket being presented in ambiguous locations between the two learnt locations, and the response of the sheep (go/no-go) measured their judgement of the bucket locations. Following 5 days of treatment, pCPA-treated sheep approached the most positive ambiguous location significantly less than control sheep, suggesting a pessimistic-like bias (treatment × bucket location interaction F(1,124.6)=49.97, p=0.011). A trend towards a significant interaction was still evident 5 days after the cessation of pCPA treatment (p=0.068), however no significant interaction was seen on day 3 of testing (p=0.867). These results support the suggestion that judgement bias is a cognitive measure of affective state, and that the serotonergic pathway may be involved. Crown Copyright © 2010. Published by Elsevier Ltd. All rights reserved.

  17. Age-related differences in the rate and diagnosis of 30-day readmission after hospitalization for acute ischemic stroke.

    PubMed

    Hirayama, Atsushi; Goto, Tadahiro; Faridi, Mohammad K; Camargo, Carlos A; Hasegawa, Kohei

    2018-01-01

    Background Little is known about the association between age and readmission within 30 days after hospitalization for acute ischemic stroke. Aim To examine the age-related differences in rate and principal reason of 30-day readmissions in patients hospitalized for acute ischemic stroke. Methods In this retrospective, population-based cohort study using State Inpatient Databases from eight US states, we identified all adults hospitalized for acute ischemic stroke. We grouped the patients into four age categories: < 65, 65-74, 75-84, and ≥85 years. Outcomes were any-cause readmission within 30 days of discharge from the index hospitalization for acute ischemic stroke and the principal diagnosis of 30-day readmission. Results We identified 620,788 hospitalizations for acute ischemic stroke. The overall 30-day readmission rate was 16.6% with an increase with advanced age. Compared to patients aged <65 years, the readmission rate was significantly higher in age 65-74 years (OR 1.19; 95% CI 1.16-1.21), in age 75-84 years (OR 1.29; 95% CI 1.27-1.31), and in ≥ 85 years (OR 1.24; 95% CI 1.22-1.27; all P<0.001). There was heterogeneity in the age-readmission rate association between men and women (P interaction  < 0.001). Overall, 45.8% of readmissions were assigned stroke-related conditions or rehabilitation care. Compared to younger adults, older adults were more likely to present with non-stroke-related conditions (46.1% in < 65 years, 50.6% in 65-74 years, 57.1% in 75-84 years, and 62.9% in ≥ 85 years; P<0.001). Conclusions Advanced age was associated with a higher 30-day readmission rate after acute ischemic stroke. Compared with younger adults, older adults were more likely to be readmitted for non-stroke-related conditions.

  18. How restful is it with all that noise? Comparison of Interleaved silent steady state (ISSS) and conventional imaging in resting-state fMRI.

    PubMed

    Andoh, J; Ferreira, M; Leppert, I R; Matsushita, R; Pike, B; Zatorre, R J

    2017-02-15

    Resting-state fMRI studies have become very important in cognitive neuroscience because they are able to identify BOLD fluctuations in brain circuits involved in motor, cognitive, or perceptual processes without the use of an explicit task. Such approaches have been fruitful when applied to various disordered populations, or to children or the elderly. However, insufficient attention has been paid to the consequences of the loud acoustic scanner noise associated with conventional fMRI acquisition, which could be an important confounding factor affecting auditory and/or cognitive networks in resting-state fMRI. Several approaches have been developed to mitigate the effects of acoustic noise on fMRI signals, including sparse sampling protocols and interleaved silent steady state (ISSS) acquisition methods, the latter being used only for task-based fMRI. Here, we developed an ISSS protocol for resting-state fMRI (rs-ISSS) consisting of rapid acquisition of a set of echo planar imaging volumes following each silent period, during which the steady state longitudinal magnetization was maintained with a train of relatively silent slice-selective excitation pulses. We evaluated the test-retest reliability of intensity and spatial extent of connectivity networks of fMRI BOLD signal across three different days for rs-ISSS and compared it with a standard resting-state fMRI (rs-STD). We also compared the strength and distribution of connectivity networks between rs-ISSS and rs-STD. We found that both rs-ISSS and rs-STD showed high reproducibility of fMRI signal across days. In addition, rs-ISSS showed a more robust pattern of functional connectivity within the somatosensory and motor networks, as well as an auditory network compared with rs-STD. An increased connectivity between the default mode network and the language network and with the anterior cingulate cortex (ACC) network was also found for rs-ISSS compared with rs-STD. Finally, region of interest analysis showed higher interhemispheric connectivity in Heschl's gyri in rs-ISSS compared with rs-STD, with lower variability across days. The present findings suggest that rs-ISSS may be advantageous for detecting network connectivity in a less noisy environment, and that resting-state studies carried out with standard scanning protocols should consider the potential effects of loud noise on the measured networks. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. A one-dimensional, steady-state, dissolved-oxygen model and waste-load assimilation study for Duck Creek, Madison, Tipton, and Hamilton counties, Indiana

    USGS Publications Warehouse

    Crawford, Charles G.; Wilber, William G.; Peters, James G.

    1980-01-01

    The Indiana State Board of Health is developing a State water-quality plan that includes establishing limits for wastewater effluents discharged into Indiana streams. A digital model calibrated to conditions in Duck Creek was used to develop alternatives for future waste loadings that would be compatible with Indiana stream water-quality standards defined for two critical hydrologic conditions, summer and winter low flows. The major point-source waste load affecting Duck Creek is the Elwood wastewater-treatment facility. Natural streamflow during the low flow is zero, so no benefit from dilution is provided. Natural reaeration at the low-flow condition (approximately 3 cubic feet per second), also low, is estimated to be less than 1 per day (base e at 20 Celsius). Consequently, the wasteload assimilative capacity of the stream is low. Effluent ammonia-nitrogen concentrations, projected by the Indiana State Board of Health, will result in stream ammonia-nitrogen concentrations that exceed the State ammonia-nitrogen toxicity standards (2.5 milligrams per liter from April to October and 4.0 milligrams per liter from November through March). The projected effluent ammonia-nitrogen load will also result in the present Indiana stream dissolved-oxygen standard (5.0 milligrams per liter) not being met. Benthic-oxygen demand may also affect stream water quality. During the summer low-flow, a benthic-oxygen demand of only 0.6 gram per square meter per day would utilize all the streams 's available assimilative capacity. (USGS)

  20. Assessment of Image Quality of Repeated Limited Transthoracic Echocardiography After Cardiac Surgery.

    PubMed

    Canty, David J; Heiberg, Johan; Tan, Jen A; Yang, Yang; Royse, Alistair G; Royse, Colin F; Mobeirek, Abdulelah; Shaer, Fayez El; Albacker, Turki; Nazer, Rakan I; Fouda, Muhammed; Bakir, Bakir M; Alsaddique, Ahmed A

    2017-06-01

    The use of limited transthoracic echocardiography (TTE) has been restricted in patients after cardiac surgery due to reported poor image quality. The authors hypothesized that the hemodynamic state could be evaluated in a high proportion of patients at repeated intervals after cardiac surgery. Prospective observational study. Tertiary university hospital. The study comprised 51 patients aged 18 years or older presenting for cardiac surgery. Patients underwent TTE before surgery and at 3 time points after cardiac surgery. Images were assessed offline using an image quality scoring system by 2 expert observers. Hemodynamic state was assessed using the iHeartScan protocol, and the primary endpoint was the proportion of limited TTE studies in which the hemodynamic state was interpretable at each of the 3 postoperative time points. Hemodynamic state interpretability varied over time and was highest before surgery (90%) and lowest on the first postoperative day (49%) (p<0.01). This variation in interpretability over time was reflected in all 3 transthoracic windows, ranging from 43% to 80% before surgery and from 2% to 35% on the first postoperative day (p<0.01). Image quality scores were highest with the apical window, ranging from 53% to 77% across time points, and lowest with the subcostal window, ranging from 4% to 70% across time points (p< 0.01). Hemodynamic state can be determined with TTE in a high proportion of cardiac surgery patients after extubation and removal of surgical drains. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Effects of Marijuana Use on Impulsivity and Hostility in Daily Life

    PubMed Central

    Ansell, Emily B.; Laws, Holly B.; Roche, Michael J.; Sinha, Rajita

    2015-01-01

    BACKGROUND Marijuana use is increasingly prevalent among young adults. While research has found adverse effects associated with marijuana use within experimentally controlled laboratory settings, it is unclear how recreational marijuana use affects day-to-day experiences in users. The present study sought to examine the effects of marijuana use on within-person changes in impulsivity and interpersonal hostility in daily life using smartphone administered assessments. METHODS Forty-three participants with no substance dependence reported on their alcohol consumption, tobacco use, recreational marijuana use, impulsivity, and interpersonal hostility over the course of 14 days. Responses were analyzed using multilevel modeling. RESULTS Marijuana use was associated with increased impulsivity on the same day and the following day relative to days when marijuana was not used, independent of alcohol use. Marijuana was also associated with increased hostile behaviors and perceptions of hostility in others on the same day when compared to days when marijuana was not used. These effects were independent of frequency of marijuana use or alcohol use. There were no significant effects of alcohol consumption on impulsivity or interpersonal hostility. CONCLUSIONS Marijuana use is associated with changes in impulse control and hostility in daily life. This may be one route by which deleterious effects of marijuana are observed for mental health and psychosocial functioning. Given the increasing prevalence of recreational marijuana use and the potential legalization in some states, further research on the potential consequences of marijuana use in young adults’ day-to-day life is warranted. PMID:25595054

  2. Unsupported inferences of high-severity fire in historical dry forests of the western United States: Response to Williams and Baker

    USGS Publications Warehouse

    Fulé, Peter Z.; Swetnam, Thomas W.; Brown, Peter M.; Falk, Donald A.; Peterson, David L.; Allen, Craig D.; Aplet, Gregory H.; Battaglia, Mike A.; Binkley, Dan; Farris, Calvin; Keane, Robert E.; Margolis, Ellis Q.; Grissino-Mayer, Henri; Miller, Carol; Sieg, Carolyn Hull; Skinner, Carl; Stephens, Scott L.; Taylor, Alan

    2014-01-01

    Reconstructions of dry western US forests in the late 19th century in Arizona, Colorado and Oregon based on General Land Office records were used by Williams & Baker (2012; Global Ecology and Biogeography, 21, 1042–1052; hereafter W&B) to infer past fire regimes with substantial moderate and high-severity burning. The authors concluded that present-day large, high-severity fires are not distinguishable from historical patterns. We present evidence of important errors in their study. First, the use of tree size distributions to reconstruct past fire severity and extent is not supported by empirical age–size relationships nor by studies that directly quantified disturbance history in these forests. Second, the fire severity classification of W&B is qualitatively different from most modern classification schemes, and is based on different types of data, leading to an inappropriate comparison. Third, we note that while W&B asserted ‘surprising’ heterogeneity in their reconstructions of stand density and species composition, their data are not substantially different from many previous studies which reached very different conclusions about subsequent forest and fire behaviour changes. Contrary to the conclusions of W&B, the preponderance of scientific evidence indicates that conservation of dry forest ecosystems in the western United States and their ecological, social and economic value is not consistent with a present-day disturbance regime of large, high-severity fires, especially under changing climate

  3. Decrease in Hysteresis of Planetary Climate for Planets with Long Solar Days

    NASA Astrophysics Data System (ADS)

    Abbot, Dorian S.; Bloch-Johnson, Jonah; Checlair, Jade; Farahat, Navah X.; Graham, R. J.; Plotkin, David; Popovic, Predrag; Spaulding-Astudillo, Francisco

    2018-02-01

    The ice-albedo feedback on rapidly rotating terrestrial planets in the habitable zone can lead to abrupt transitions (bifurcations) between a warm and a snowball (ice-covered) state, bistability between these states, and hysteresis in planetary climate. This is important for planetary habitability because snowball events may trigger rises in the complexity of life, but could also endanger complex life that already exists. Recent work has shown that planets tidally locked in synchronous rotation states will transition smoothly into the snowball state rather than experiencing bifurcations. Here we investigate the structure of snowball bifurcations on planets that are tidally influenced, but not synchronously rotating, so that they experience long solar days. We use PlaSIM, an intermediate-complexity global climate model, with a thermodynamic mixed layer ocean and the Sun’s spectrum. We find that the amount of hysteresis (the range in stellar flux for which there is bistability in climate) is significantly reduced for solar days with lengths of tens of Earth days, and disappears for solar days of hundreds of Earth days. These results suggest that tidally influenced planets orbiting M and K stars that are not synchronously rotating could have much less hysteresis associated with the snowball bifurcations than they would if they were rapidly rotating. This implies that the amount of time it takes them to escape a snowball state via CO2 outgassing would be greatly reduced, as would the period of cycling between the warm and snowball state if they have low CO2 outgassing rates.

  4. Transmission of yellow fever vaccine virus through breast-feeding - Brazil, 2009.

    PubMed

    2010-02-12

    In April, 2009, the state health department of Rio Grande do Sul, Brazil, was notified by the Cachoeira do Sul municipal health department of a case of meningoencephalitis requiring hospitalization in an infant whose mother recently had received yellow fever vaccine during a postpartum visit. The Field Epidemiology Training Program of the Secretariat of Surveillance in Health of the Brazilian Ministry of Health assisted state and municipal health departments with an investigation. This report summarizes the results of that investigation, which determined that the infant acquired yellow fever vaccine virus through breast-feeding. The mother reported 2 days of headache, malaise, and low fever occurring 5 days after receipt of yellow fever vaccine. The infant, who was exclusively breast-fed, was hospitalized at age 23 days with seizures requiring continuous infusion of intravenous anticonvulsants. The infant received antimicrobial and antiviral treatment for meningoencephalitis. The presence of 17DD yellow fever virus was detected by reverse transcription--polymerase chain reaction (RT-PCR) in the infant's cerebrospinal fluid (CSF); yellow fever--specific immunoglobulin M (IgM) antibodies also were present in serum and CSF. The infant recovered completely, was discharged after 24 days of hospitalization, and has had normal neurodevelopment and growth through age 6 months. The findings in this report provide documentation that yellow fever vaccine virus can be transmitted via breast-feeding. Administration of yellow fever vaccine to breast-feeding women should be avoided except in situations where exposure to yellow fever viruses cannot be avoided or postponed.

  5. Fatal Flea-Borne Typhus in Texas: A Retrospective Case Series, 1985–2015

    PubMed Central

    Pieracci, Emily G.; Evert, Nicole; Drexler, Naomi A.; Mayes, Bonny; Vilcins, Inger; Huang, Philip; Campbell, Jill; Behravesh, Casey Barton; Paddock, Christopher D.

    2017-01-01

    Flea-borne (murine) typhus is a global rickettsiosis caused by Rickettsia typhi. Although flea-borne typhus is no longer nationally notifiable, cases are reported for surveillance purposes in a few U.S. states. The infection is typically self-limiting, but may be severe or life-threatening in some patients. We performed a retrospective review of confirmed or probable cases of fatal flea-borne typhus reported to the Texas Department of State Health Services during 1985–2015. When available, medical charts were also examined. Eleven cases of fatal flea-borne typhus were identified. The median patient age was 62 years (range, 36–84 years) and 8 (73%) were male. Patients presented most commonly with fever (100%), nausea and vomiting (55%), and rash (55%). Respiratory (55%) and neurologic (45%) manifestations were also identified frequently. Laboratory abnormalities included thrombocytopenia (82%) and elevated hepatic transaminases (63%). Flea or animal contact before illness onset was frequently reported (55%). The median time from hospitalization to administration of a tetracycline-class drug was 4 days (range, 0–5 days). The median time from symptom onset to death was 14 days (range, 1–34 days). Flea-borne typhus can be a life-threatening disease if not treated in a timely manner with appropriate tetracycline-class antibiotics. Flea-borne typhus should be considered in febrile patients with animal or flea exposure and respiratory or neurologic symptoms of unknown etiology. PMID:28500797

  6. Prevalence of drink-driving among adults in China: A nationally representative survey in 2010.

    PubMed

    Xiao, Deng; Pengpeng, Ye; Yichong, Li; Leilei, Duan; Limin, Wang; Shults, Ruth A; Roehler, Douglas R; Yee, Sue Lin

    2017-11-17

    We examined the prevalence of and characteristics associated with drink-driving in China. We compared this study's drink-driving findings with those from the United States to explore how effective traffic safety interventions from Western cultures might be adapted for use in China. Data from the 2010 China Chronic Disease and Risk Factor Survey were analyzed to describe the prevalence and characteristics associated with drink-driving in China. Overall, 1.5% of Chinese adults reported drink-driving in the past 30 days-3% of males and 0.1% of females. However, among males who had driven a vehicle in the past 30 days and consumed at least one alcoholic beverage in the past 30 days, 19% reported drink-driving during the 30-day period. Excessive drinking, binge drinking, nonuse of seat belts, and having been injured in a road traffic crash in the past year were most strongly associated with drink-driving among males. Drink-driving is prevalent among male drivers in China. Although large differences exist between China and the United States in the proportion of adults who drive, the proportion who consume alcohol, and some of the personal characteristics of those who drink and drive, similarities between the 2 countries are present in patterns of risk behaviors among drink-driving. To reduce injuries and deaths from drink-driving, effective interventions from Western cultures need to be tailored for adoption in China.

  7. Impacts of global warming on residential heating and cooling degree-days in the United States

    PubMed Central

    Petri, Yana; Caldeira, Ken

    2015-01-01

    Climate change is expected to decrease heating demand and increase cooling demand for buildings and affect outdoor thermal comfort. Here, we project changes in residential heating degree-days (HDD) and cooling degree-days (CDD) for the historical (1981–2010) and future (2080–2099) periods in the United States using median results from the Climate Model Intercomparison Project phase 5 (CMIP5) simulations under the Representation Concentration Pathway 8.5 (RCP8.5) scenario. We project future HDD and CDD values by adding CMIP5 projected changes to values based on historical observations of US climate. The sum HDD + CDD is an indicator of locations that are thermally comfortable, with low heating and cooling demand. By the end of the century, station median HDD + CDD will be reduced in the contiguous US, decreasing in the North and increasing in the South. Under the unmitigated RCP8.5 scenario, by the end of this century, in terms of HDD and CDD values considered separately, future New York, NY, is anticipated to become more like present Oklahoma City, OK; Denver, CO, becomes more like Raleigh, NC, and Seattle, WA, becomes more like San Jose, CA. These results serve as an indicator of projected climate change and can help inform decision-making. PMID:26238673

  8. Treadmill exercise alleviates depressive symptoms in rotenone-induced Parkinson disease rats

    PubMed Central

    Shin, Mal-Soon; Kim, Tae-Woon; Lee, Jae-Min; Sung, Yun-Hee; Lim, Baek-Vin

    2017-01-01

    Parkinson disease (PD) is characterized by selective loss of the dopaminergic neurons. The symptoms of depression following PD are closely associated with reduced activity of the serotonergic system in the dorsal raphe. We explored the antidepressive effect of exercise and its possible mechanism using the rotenone-induced PD rats. PD rats were induced by subcutaneously injection with rotenone for 14 days. The rats in the exercise groups were made to run on a treadmill for 30 min once a day during 14 consecutive days. Forced swimming test, immunohistochemistry for serotonin (5-hydroxytryptamine, 5-HT), tryptophan hydroxylase (TPH), and western blot for serotonin 1A (5-HT1A) receptor were conducted. Injection of rotenone induced PD rats. PD rats showed depressive state and treadmill exercise ameliorated this depressive state. 5-HT, TPH, and 5-HT1A receptor expressions in the dorsal raphe were suppressed by rotenone injection and treadmill exercise increased the expressions of 5-HT, TPH, and 5-HT1A receptor in the rotenone-injected rats. The present results show that treadmill exercise ameliorated depressive symptoms in the rotenone-induced PD rats. The antidepressive effect of treadmill exercise might be ascribed to the enhancement of serotonergic function through upregulation of 5-HT1A expression in the dorsal raphe. PMID:28503522

  9. Treadmill exercise alleviates depressive symptoms in rotenone-induced Parkinson disease rats.

    PubMed

    Shin, Mal-Soon; Kim, Tae-Woon; Lee, Jae-Min; Sung, Yun-Hee; Lim, Baek-Vin

    2017-04-01

    Parkinson disease (PD) is characterized by selective loss of the dopaminergic neurons. The symptoms of depression following PD are closely associated with reduced activity of the serotonergic system in the dorsal raphe. We explored the antidepressive effect of exercise and its possible mechanism using the rotenone-induced PD rats. PD rats were induced by subcutaneously injection with rotenone for 14 days. The rats in the exercise groups were made to run on a treadmill for 30 min once a day during 14 consecutive days. Forced swimming test, immunohistochemistry for serotonin (5-hydroxytryptamine, 5-HT), tryptophan hydroxylase (TPH), and western blot for serotonin 1A (5-HT1A) receptor were conducted. Injection of rotenone induced PD rats. PD rats showed depressive state and treadmill exercise ameliorated this depressive state. 5-HT, TPH, and 5-HT1A receptor expressions in the dorsal raphe were suppressed by rotenone injection and treadmill exercise increased the expressions of 5-HT, TPH, and 5-HT1A receptor in the rotenone-injected rats. The present results show that treadmill exercise ameliorated depressive symptoms in the rotenone-induced PD rats. The antidepressive effect of treadmill exercise might be ascribed to the enhancement of serotonergic function through upregulation of 5-HT1A expression in the dorsal raphe.

  10. [Study of the virus carrier state in chicken influenza].

    PubMed

    Smolenskiĭ, V I; Osidze, N G; Bogautdinov, Z F; Panteleev, Iu V; Siurin, V N

    1978-01-01

    The problems of virus carrier state in influenza are connected with two aspects of the disease: the duration of virus antigen persistence in convalescents and changes of influenza virus properties in the course of persistence. In the present study, natural influenza infection in chickens caused by influenza A/chicken/USSR/336/74 virus (Hav6H3--N2) was used to determine the duration of virus antigen persistence (up to 60 days) and the entire period of virus isolation from the survivers (up to 30 days). Administration of hydrocortisone on the 50th day of convalescence permitted to obtain from the chickens several influenza A virus isolates antigenically unrelated to the epizootic strain either in hemagglutinin or in neuraminidase. Cultivation of isolate No. 42 (Hav7Neq1) in the presence of the homologous serum yielded strain 42' which was neutralized by the serum to Hav6H3--N2 virus. The isolates differed from the epizootic virus by their biological properties: the eluting activity, pathogenesis and morphology. The above facts of antigenic variability are considered in the light of the antigenic heterogeneity of the natural virus population and the possibility of virus activation by the provoking effect of extreme conditions on the carriers of latent infection.

  11. Impacts of global warming on residential heating and cooling degree-days in the United States.

    PubMed

    Petri, Yana; Caldeira, Ken

    2015-08-04

    Climate change is expected to decrease heating demand and increase cooling demand for buildings and affect outdoor thermal comfort. Here, we project changes in residential heating degree-days (HDD) and cooling degree-days (CDD) for the historical (1981-2010) and future (2080-2099) periods in the United States using median results from the Climate Model Intercomparison Project phase 5 (CMIP5) simulations under the Representation Concentration Pathway 8.5 (RCP8.5) scenario. We project future HDD and CDD values by adding CMIP5 projected changes to values based on historical observations of US climate. The sum HDD + CDD is an indicator of locations that are thermally comfortable, with low heating and cooling demand. By the end of the century, station median HDD + CDD will be reduced in the contiguous US, decreasing in the North and increasing in the South. Under the unmitigated RCP8.5 scenario, by the end of this century, in terms of HDD and CDD values considered separately, future New York, NY, is anticipated to become more like present Oklahoma City, OK; Denver, CO, becomes more like Raleigh, NC, and Seattle, WA, becomes more like San Jose, CA. These results serve as an indicator of projected climate change and can help inform decision-making.

  12. The interplay between daily affect and sleep: a 2-week study of young women.

    PubMed

    Kalmbach, David A; Pillai, Vivek; Roth, Thomas; Drake, Christopher L

    2014-12-01

    Little attention has been paid to the relation between daily affect and sleep, as most prior studies have focused instead on the role of pathological mood in the context of sleep disturbance. However, understanding the transaction between normal variations in emotional experiences and sleep can shed light on the premorbid vulnerabilities that trigger the evolution of affect and sleep into more problematic states. The present study used a 2-week daily sampling approach to examine the impact of day-to-day variations in positive and negative affect on nightly self-reported sleep-onset latency, sleep duration and sleep quality in a sample of young women. Hierarchical linear modelling revealed temporal relations between positive and negative affect states and sleep parameters. Specifically, different aspects of both positive and negative affect were uniquely predictive of sleep indices, with sadness and serenity acting as the most consistent predictors. Additionally, better sleep quality was predictive of greater happiness the following day. These results highlight the importance of how our daily emotional experiences influence our nightly sleep and, in turn, how our sleep has an impact on our daily affect. Moreover, our findings may offer insight into the progression of normative levels of affect and sleep as they develop into comorbid depression, anxiety and insomnia. © 2014 European Sleep Research Society.

  13. Monitoring the microbial community during solid-state acetic acid fermentation of Zhenjiang aromatic vinegar.

    PubMed

    Xu, Wei; Huang, Zhiyong; Zhang, Xiaojun; Li, Qi; Lu, Zhenming; Shi, Jinsong; Xu, Zhenghong; Ma, Yanhe

    2011-09-01

    Zhenjiang aromatic vinegar is one of the most famous Chinese traditional vinegars. In this study, change of the microbial community during its fermentation process was investigated. DGGE results showed that microbial community was comparatively stable, and the diversity has a disciplinary series of changes during the fermentation process. It was suggested that domestication of microbes and unique cycle-inoculation style used in the fermentation of Zhenjiang aromatic vinegar were responsible for comparatively stable of the microbial community. Furthermore, two clone libraries were constructed. The results showed that bacteria presented in the fermentation belonged to genus Lactobacillus, Acetobacter, Gluconacetobacter, Staphylococcus, Enterobacter, Pseudomonas, Flavobacterium and Sinorhizobium, while the fungi were genus Saccharomyces. DGGE combined with clone library analysis was an effective and credible technique for analyzing the microbial community during the fermentation process of Zhenjiang aromatic vinegar. Real-time PCR results suggested that the biomass showed a "system microbes self-domestication" process in the first 5 days, then reached a higher level at the 7th day before gradually decreasing until the fermentation ended at the 20th day. This is the first report to study the changes of microbial community during fermentation process of Chinese traditional solid-state fermentation of vinegar. Copyright © 2011 Elsevier Ltd. All rights reserved.

  14. Space Shuttle Day-of-Launch Trajectory Design and Verification

    NASA Technical Reports Server (NTRS)

    Harrington, Brian E.

    2010-01-01

    A top priority of any launch vehicle is to insert as much mass into the desired orbit as possible. This requirement must be traded against vehicle capability in terms of dynamic control, thermal constraints, and structural margins. The vehicle is certified to a specific structural envelope which will yield certain performance characteristics of mass to orbit. Some envelopes cannot be certified generically and must be checked with each mission design. The most sensitive envelopes require an assessment on the day-of-launch. To further minimize vehicle loads while maximizing vehicle performance, a day-of-launch trajectory can be designed. This design is optimized according to that day s wind and atmospheric conditions, which will increase the probability of launch. The day-of-launch trajectory verification is critical to the vehicle's safety. The Day-Of-Launch I-Load Uplink (DOLILU) is the process by which the Space Shuttle Program redesigns the vehicle steering commands to fit that day's environmental conditions and then rigorously verifies the integrated vehicle trajectory's loads, controls, and performance. The Shuttle methodology is very similar to other United States unmanned launch vehicles. By extension, this method would be similar to the methods employed for any future NASA launch vehicles. This presentation will provide an overview of the Shuttle's day-of-launch trajectory optimization and verification as an example of a more generic application of dayof- launch design and validation.

  15. Teachers' Perception of School Climate in Independent Jewish Day Schools in Relation to Change and Transition of Leadership Personnel

    ERIC Educational Resources Information Center

    Knafo, Sharon

    2012-01-01

    This study examined the relationship between turnover of school leadership personnel and school climate as perceived by teachers. The study focused on Jewish day schools in the United States in different cities and states. Fifty Jewish day schools (ranging from preschool age to high school) participated in the study with 200 teachers from these…

  16. Workdays, Workhours, and Work Schedules: Evidence for the United States and Germany.

    ERIC Educational Resources Information Center

    Hamermesh, Daniel S.

    This book studies work in the United States and Germany from two new viewpoints: (1) the division of work time into hours per day and days per week (as opposed to the standard analysis of weekly hours of work); and (2) the patterns of the particular times of the day and week when people are working, a focus on instantaneous time use. Information…

  17. A Review of Federal and State Regulations for Day Care Programs and Facilities. Center for Human Services Development Report No. 10.

    ERIC Educational Resources Information Center

    Hollick, Rosemary; And Others

    This report provides a review of U.S. regulatory standards for day care programs and facilities and makes recommendations for the revision of day care regulations in Pennsylvania. Following a brief discussion of federal interagency requirements, a number of short descriptive analyses compare individual state standards in the areas of licensing,…

  18. Meeting of the Central and Eastern U.S. (CEUS) Earthquake Hazards Program October 28–29, 2009

    USGS Publications Warehouse

    Tuttle, Martitia; Boyd, Oliver; McCallister, Natasha

    2013-01-01

    On October 28th and 29th, 2009, the U.S. Geological Survey Earthquake Hazards Program held a meeting of Central and Eastern United States investigators and interested parties in Memphis, Tennessee. The purpose of the meeting was to bring together the Central and Eastern United States earthquake-hazards community to present and discuss recent research results, to promote communication and collaboration, to garner input regarding future research priorities, to inform the community about research opportunities afforded by the 2010–2012 arrival of EarthScope/USArray in the central United States, and to discuss plans for the upcoming bicentennial of the 1811–1812 New Madrid earthquakes. The two-day meeting included several keynote speakers, oral and poster presentations by attendees, and breakout sessions. The meeting is summarized in this report and can be subdivided into four primary sections: (1) summaries of breakout discussion groups; (2) list of meeting participants; (3) submitted abstracts; and (4) slide presentations. The abstracts and slides are included “as submitted” by the meeting participants and have not been subject to any formal peer review process; information contained in these sections reflects the opinions of the presenter at the time of the meeting and does not constitute endorsement by the U.S. Geological Survey.

  19. Modelling interstellar physics and chemistry: implications for surface and solid-state processes.

    PubMed

    Williams, David; Viti, Serena

    2013-07-13

    We discuss several types of regions in the interstellar medium of the Milky Way and other galaxies in which the chemistry appears to be influenced or dominated by surface and solid-state processes occurring on or in interstellar dust grains. For some of these processes, for example, the formation of H₂ molecules, detailed experimental and theoretical approaches have provided excellent fundamental data for incorporation into astrochemical models. In other cases, there is an astrochemical requirement for much more laboratory and computational study, and we highlight these needs in our description. Nevertheless, in spite of the limitations of the data, it is possible to infer from astrochemical modelling that surface and solid-state processes play a crucial role in astronomical chemistry from early epochs of the Universe up to the present day.

  20. Health-related quality of life surveillance--United States, 1993-2002.

    PubMed

    Zahran, Hatice S; Kobau, Rosemarie; Moriarty, David G; Zack, Matthew M; Holt, James; Donehoo, Ralph

    2005-10-28

    Population-based surveillance of health-related quality of life (HRQOL) is needed to promote the health and quality of life of U.S. residents and to monitor progress in achieving the two overall Healthy People 2010 goals: 1) increase the quality and years of healthy life and 2) eliminate health disparities. This report examines surveillance-based HRQOL data from 1993 through 2002. Survey data from a validated set of HRQOL measures (CDC HRQOL-4) were analyzed for 1993-2001 from the Behavioral Risk Factor Surveillance System (BRFSS) surveys for the 50 states and the District of Columbia (DC) and for 2001-2002 from the National Health and Nutrition Examination Survey (NHANES). These measures assessed self-rated health; physically unhealthy days (i.e., the number of days during the preceding 30 days for which physical health, including physical illness and injury, was not good); mentally unhealthy days (i.e., the number of days during the preceding 30 days for which mental health, including stress, depression, and problems with emotions, was not good); and days with activity limitation (i.e., number of days during the preceding 30 days that poor physical or mental health prevented normal daily activities). A summary measure of overall unhealthy days also was computed from the sum of a respondent's physically unhealthy and mentally unhealthy days, with a maximum of 30 days. During 1993-2001, the mean number of physically unhealthy days, mentally unhealthy days, overall unhealthy days, and activity limitation days was higher after 1997 than before 1997. During 1993-1997, the percentage of respondents with zero overall unhealthy days was stable (51%-53%) but declined to 48% by 2001. The percentage of respondents with >/=14 overall unhealthy days increased from 15%-16% during 1993-1997 to 18% by 2001. Adults increasingly rated their health as fair or poor and decreasingly rated it as excellent or very good. Women, American Indians/Alaska Natives, persons of "other races," separated or divorced persons, unmarried couples, unemployed persons, those unable to work, those with a <$15,000 annual household income, and those with less than a high school education reported worse HRQOL (i.e., physically unhealthy days, mentally unhealthy days, overall unhealthy days, and activity limitation days). Older adults reported more physically unhealthy days and activity limitation days, whereas younger adults reported more mentally unhealthy days. A seasonal pattern was observed in physically unhealthy days and overall unhealthy days. During 1993-2001, BRFSS respondents in 13 states reported increasing physically unhealthy days; respondents in 13 states and DC reported increasing mentally unhealthy days; respondents in Alabama, Connecticut, Maine, New Jersey, New Mexico, North Carolina, and Oregon reported both increasing physically and mentally unhealthy days; and respondents in 16 states and DC reported increasing activity limitation days. During 2001-2002, NHANES respondents with one or more medical conditions (e.g., arthritis or stroke) reported worse HRQOL than those without such conditions, and those with an increasing number of medical conditions reported increasingly worse HRQOL. Policy makers and researchers should continue to monitor HRQOL and its correlates in the U.S. population. In addition, public health professionals should expand monitoring to populations currently missed by existing surveys, including institutionalized and homeless persons, adolescents, and children. A key aspect is to study and identify the personal and community determinants of HRQOL in prevention research and population studies, to understand how to improve HRQOL, and to reduce HRQOL disparities. In addition, population health assessment professionals should continue to refine and validate HRQOL, functional status, and self-reported health measures.

  1. Characterising the three-dimensional ozone distribution of a tidally locked Earth-like planet

    NASA Astrophysics Data System (ADS)

    Proedrou, Elisavet; Hocke, Klemens

    2016-06-01

    We simulate the 3D ozone distribution of a tidally locked Earth-like exoplanet using the high-resolution, 3D chemistry-climate model CESM1(WACCM) and study how the ozone layer of a tidally locked Earth (TLE) (Ω _{TLE}= 1/365 days) differs from that of our present-day Earth (PDE) (Ω _{PDE}= 1/1 day). The middle atmosphere reaches a steady state asymptotically within the first 80 days of the simulation. An upwelling, centred on the subsolar point, is present on the day side while a downwelling, centred on the antisolar point, is present on the night side. In the mesosphere, we find similar global ozone distributions for the TLE and the PDE, with decreased ozone on the day side and enhanced ozone on the night side. In the lower mesosphere, a jet stream transitions into a large-scale vortex around a low-pressure system, located at low latitudes of the TLE night side. In the middle stratosphere, the concentration of odd oxygen is approximately equal to that of the ozone [({O}x) ≈ ({O}3)]. At these altitudes, the lifetime of odd oxygen is ˜16 h and the transport processes significantly contribute to the global distribution of stratospheric ozone. Compared to the PDE, where the strong Coriolis force acts as a mixing barrier between low and high latitudes, the transport processes of the TLE are governed by jet streams variable in the zonal and meridional directions. In the middle stratosphere of the TLE, we find high ozone values on the day side, due to the increased production of atomic oxygen on the day side, where it immediately recombines with molecular oxygen to form ozone. In contrast, the ozone is depleted on the night side, due to changes in the solar radiation distribution and the presence of a downwelling. As a result of the reduced Coriolis force, the tropical and extratropical air masses are well mixed and the global temperature distribution of the TLE stratosphere has smaller horizontal gradients than the PDE. Compared to the PDE, the total ozone column global mean is reduced by ˜19.3 %. The day side and the night side total ozone column means are reduced by 23.21 and 15.52 %, respectively. Finally, we present the total ozone column (TOC) maps as viewed by a remote observer for four phases of the TLE during its revolution around the star. The mean TOC values of the four phases of the TLE vary by up to 23 %.

  2. Electrocardiogram transmission - The state of the art.

    NASA Technical Reports Server (NTRS)

    Firstenberg, A.; Huston, S. W.; Olsen, D. E.; Hahn, P. M.

    1971-01-01

    A comparative analysis of available clinical EKG telemetry systems was conducted. Although present day electrocardiogram diagnosis requires a high degree of measurement accuracy, there exists wide variations in the performance characteristics of the various telemeters marketed today necessitating careful consideration of specifications prior to procurement. The authors have endeavored to provide the physicians with a clear understanding, in terms of the effects on the electrocardiogram, of the factors he must evaluate in order to ensure high fidelity EKG reproduction. A tabulation of comparative parameter values for each unit obtained from manufacturers' specifications and substantiated by standardized performance tests conducted in our laboratory is presented.

  3. Expanding your horizons in science and mathematics

    NASA Technical Reports Server (NTRS)

    1985-01-01

    Through the presentation of its Expanding Your Horizons in Science and Mathematics career education conferences for secondary school young women, the Math/Science Network continues its efforts to remove the educational, psychological, and cultural barriers which prevent women from entering math-and science-based careers. The Expanding Your Horizons conferences were presented on 77 college, university and high school campuses across the United States. This year, these unique one day conferences reached 15,500 students, 3,000 parents and educators, and involved 3,000 career women who volunteered their services as conference planners, workshop leaders, speakers, and role models.

  4. Historic and Current Launcher Success Rates

    NASA Technical Reports Server (NTRS)

    Rust, Randy

    2002-01-01

    This presentation reviews historic and current space launcher success rates from all nations with a mature launcher industry. Data from the 1950's through present day is reviewed for possible trends such as when in the launch timeline a failure occurred, which stages had the highest failure rate, overall launcher reliability, a decade by decade look at launcher reliability, when in a launchers history did failures occur, and the reliability of United States human-rated launchers. This information is useful in determining where launcher reliability can be improved and where additional measures for crew survival (i.e., Crew Escape systems) will have the greatest emphasis

  5. Review of ESOC re-entry prediction results of Salyut-7/Kosmos-1686

    NASA Technical Reports Server (NTRS)

    Klinkrad, H.

    1991-01-01

    An overview of activities at ESA/ESOC during the followup of the Salyut-7/Kosmos-1686 decay, and of related cooperations with space agencies, research institutes, and national bodies within the ESA Member States, within the U.S. and within the USSR, is presented. A postflight analysis indicated areas for improvement in the forecast procedures, especially during the last day of the orbital lifetime. Corresponding revised decay predictions are presented for Salyut-7/Kosmos-1686, and the improved procedures are verified by an analysis of the reentries of Kosmos-1402A and Kosmos-1402C.

  6. Perfluorooctanoate: Placental and lactational transport pharmacokinetics in rats.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hinderliter, Paul M.; Mylchreest, E.; Gannon, S. A.

    This study was conducted to develop a quantitative understanding of the potential for gestational and lactational transfer of perfluorooctanoate (PFOA) in the rat. Time-mated female rats were dosed by oral gavage once daily at concentrations of 3, 10, or 30 mg/kg/day of the ammonium salt of PFOA (APFO) starting on gestation (G) day 4 and continuing until sacrifice. On days 10, 15, and 21G, five rats per dose level were sacrificed and blood samples were collected 2h post-dose. Embryos were collected on day 10G, amniotic fluid, placentas, and embryos/fetuses were collected on days 15 and 21G, and fetal blood samplesmore » were collected on day 21G. Five rats per dose level were allowed to deliver and nurse their litters, and on days 3, 7, 14, and 21 post-partum (PP) milk and blood samples of maternal and pup were collected 2h post-dose. All samples were analyzed by high-performance liquid chromatography-mass spectrometry (HPLC-MS) for PFOA concentration. Concentrations of PFOA in maternal plasma and milk attained steady state during the sampling interval. The steady-state concentrations in maternal plasma were 10-15, 25-30, and 60-75 microg/mL in rats receiving 3, 10, and 30 mg/kg, respectively. Steady-state concentrations in milk were approximately 10 times less than those in maternal plasma. The concentration of PFOA in fetal plasma on day 21G was approximately half the steady-state concentration in maternal plasma. The milk concentrations appeared to be generally comparable to the concentrations in pup plasma. Pup plasma concentrations decreased from day 3PP to day 7PP, and were similar on days 7, 14, and 21PP at all dose levels. PFOA was detected in placenta (days 15 and 21G), amniotic fluid (days 15 and 21G), embryo (days 10 and 15G), and fetus (day 21G). These pharmacokinetics allow estimation of the dose to developing and nursing rat offspring following maternal exposure.« less

  7. The Use of Instructional Television in Georgia. Final Report to Georgia State Board of Education.

    ERIC Educational Resources Information Center

    Tressel, G. W.; And Others

    For the benefit of the Georgia State Board of Education, the day-to-day impact and actual problems of instructional television (ITV) as encountered in the state's classrooms has been explored and analyzed. Basic considerations were accomplishments to date and methods of improving the services. An overview of the ITV network is provided, and its…

  8. 34 CFR 300.11 - Day; business day; school day.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Day; business day; school day. 300.11 Section 300.11 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION ASSISTANCE TO STATES FOR THE EDUCATION OF...

  9. MM5 Modeling of the Madden Julian Oscillation in the Indian and West Pacific Oceans: Implications of 30 70-Day Boundary Effects on MJO Development.

    NASA Astrophysics Data System (ADS)

    Gustafson, William I., Jr.; Weare, Bryan C.

    2004-03-01

    The results of an experiment designed to isolate the initiation phase of the Madden Julian oscillation (MJO) from 30 70-day boundary effects is presented. The technique used to accomplish this involves employing the fifth-generation Pennsylvania State University National Center for Atmospheric Research (PSU NCAR) Mesoscale Model (MM5), as first presented in the companion paper to this paper. Two runs, each 2 yr long, are integrated forward from 1 June 1990. The first run, called the control, uses the unmodified National Centers for Environmental Prediction (NCEP) NCAR reanalysis (NRA) dataset for boundary conditions. The second run, called the notched, uses the same NRA dataset for the boundary conditions, with the exception that all signals with periodicities in the 30 70-day range have been removed. Any signals in the 30 70-day range subsequently generated by the notched run are then solely due to signals generated from within the model domain or from signals entering through the domain boundaries with frequencies outside of the MJO band. Comparisons between 2-yr means from each run indicate that filtering the boundaries does not significantly modify the model climatology. The mean wind structure, thermodynamic state, and outgoing longwave radiation (OLR) are almost identical in the control and notched runs. A 30 70-day bandpass filter is used to isolate MJO-like signals in the runs. Comparisons of 30 70-day bandpassed zonal wind, moist static energy (MSE), and OLR reveal that the notched run develops many of the expected characteristics of MJO episodes, but with a weaker signal. Large-scale, organized structures develop that possess seasonal shifts in amplitude, mirroring observed MJO activity, have opposite wind directions in the upper and lower troposphere, and propagate eastward during most strong episodes. The results suggest that neither remnants from previous MJO episodes nor extratropical feedbacks within the MJO time band are necessary for MJO initiation. However, the control run is more organized than the notched run, implying that 30 70 signals outside the model domain influence the MJO signal. There is also some evidence that the recharge discharge mechanism plays a role in MJO formation.

  10. Wilderness - between the promise of hell and paradise: A cultural-historical exploration of a Dutch National Park

    Treesearch

    Koen Arts; Anke Fischer; Rene van der Wal

    2011-01-01

    ‘Wilderness' is often seen as an ideal state in contemporary debates on ecological restoration. This paper asks what is left of ‘wilderness' in present-day Western Europe and explores this question by drawing on a case study of the Hoge Veluwe National Park in the Netherlands. An overview of intellectual histories of wilderness ideas is used as a backdrop to...

  11. Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference on Undergraduate Teaching of Psychology (21st, Kerhonkson, New York, March 28-30, 2007)

    ERIC Educational Resources Information Center

    Zaromatidis, Katherine, Ed.; Oswald, Patricia A., Ed.; Levine, Judith R., Ed.; Indenbaum, Gene, Ed.

    2007-01-01

    The 21st Annual Conference on Undergraduate Teaching of Psychology was held on March 28-30, 2007 at Hudson Valley Resort and Day Spa in Kerhonkson, New York. The conference was sponsored by the Psychology Department of Farmingdale State College. The conference included twenty five presentations and ten of these are included in these proceedings.…

  12. The MIT Summit Speech Recognition System: A Progress Report

    DTIC Science & Technology

    1989-01-01

    understanding of the human communication process. Despite recent development of some speech recognition systems with high accuracy, the performance of such...over the past four decades on human communication , in the hope that such systems will one day have a performance approaching that of humans. We are...optimize its use. Third, the system must have a stochastic component to deal with the present state of ignorance in our understanding of the human

  13. The Top Three Valor Awards and the United States Marine Corps: A Study from World War I to Present Day Iraq and Afghanistan

    DTIC Science & Technology

    2014-06-13

    the Medal of Honor.85 “The process by which the MOH is awarded has become flawed, and the DOD must strive to bring an end to an era of overprotection ...later in the literature review. 84Ibid., 37. 85Wes J. Deaver, “The Medal of Honor, An Era of Overprotection ,” Marine Corps Gazette 94, no. 9

  14. Needs Assessment for the Establishment of a Masters of Arts Program in International Studies with a Concentration in International Security and a Specialization in International Terrorism

    ERIC Educational Resources Information Center

    Gray, David H.

    2008-01-01

    Since the attacks of September 11, national and international security has been driven to the center stage of our present-day society, thus becoming a primary concern and focus in the United States. The purpose of this study was to conduct an instructional needs assessment for the establishment of a Masters of Arts program in International Studies…

  15. Effect of dietary nutrients on ileal endogenous losses of threonine, cysteine, methionine, lysine, leucine and protein in broiler chicks.

    PubMed

    Cerrate, S; Vignale, S K; Ekmay, R; England, J; Coon, C

    2018-04-01

    An isotope dose technique was utilized (i) to determine endogenous amino acid (AA) and protein losses and (ii) to propose adjusted values for AA requirements. The endogenous flow rate was calculated from the pool of enrichment in plasma AA, assuming similitude to enrichment of endogenous AA. In experiment 1, chicks were orally administered D4-lysine at 2% of estimated lysine intake from 16 to 24 days to find the isotopic steady state of the atom percent excess (APE) of lysine for plasma and jejunal and ileal digesta. The APE of D4-lysine in plasma, jejunal digesta and ileal digesta reached the isotopic steady state at 5.5, 3.4 and 2.0 days, respectively, by using the broken-line model. It was assumed that the isotopic steady state at 5 days identified for D4-lysine is also representative for the 15N-labeled AA. In experiment 2, chicks were fed diets from 1 to 21 days with increasing levels of fat (6%, 8%, 12%, 13% extract ether), protein (26%, 28.5%, 31% CP) or fiber (14%, 16%, 18% NDF) by adding poultry fat, soybean meal, blended animal protein or barley. Chicks were orally administered 15N-threonine, 15N-cysteine, 15N-methionine, 15N-lysine and 15N-leucine at 2% of estimated daily intake for 5 days from 17 to 21 days of age. Dietary nutrients influenced endogenous losses (EL), where dietary fat stimulated EL of lysine (P=0.06), leucine and protein (P=0.07); dietary protein enhanced EL of leucine and protein; and finally the dietary fiber increased EL of leucine. Dietary nutrients also affected apparent ileal digestibility (AID). Dietary fat increased AID of cysteine but decreased AID of lysine. Dietary protein reduced AID of protein, threonine, lysine and leucine, and similarly dietary fiber decreased AID of protein, threonine, methionine, lysine and leucine. In contrast, dietary fat or protein did not affect real ileal digestibility (RID) of protein and AA except threonine and leucine. The dietary fiber reduced the RID of protein, threonine and leucine. This indicate that variations of some endogenous AA and protein losses due to dietary nutrients almost eliminates the effects of RID, and thus the EL coming from the body should be utilized to adjust the AA requirement instead of changing the true digestible nutrients of ingredients. The present data suggest that 5 days' feeding labeled AA was enough to reach the isotopic steady state and AA requirements should be adjusted when additional dietary protein, fat or fiber is fed.

  16. Perceived insufficient rest or sleep among adults - United States, 2008.

    PubMed

    2009-10-30

    The importance of chronic sleep insufficiency is under-recognized as a public health problem, despite being associated with numerous physical and mental health problems, injury, loss of productivity, and mortality. Approximately 29% of U.S. adults report sleeping <7 hours per night and 50-70 million have chronic sleep and wakefulness disorders. A CDC analysis of 2006 data from the Behavioral Risk Factor Surveillance System (BRFSS) in four states showed that an estimated 10.1% of adults reported receiving insufficient rest or sleep on all days during the preceding 30 days. To examine the prevalence of insufficient rest or sleep in all states, CDC analyzed BRFSS data for all 50 states, the District of Columbia (DC), and three U.S. territories (Guam, Puerto Rico, and U.S. Virgin Islands) in 2008. This report summarizes the results, which showed that among 403,981 respondents, 30.7% reported no days of insufficient rest or sleep and 11.1% reported insufficient rest or sleep every day during the preceding 30 days. Females (12.4%) were more likely than males (9.9%) and non-Hispanic blacks (13.3%) were more likely than other racial/ethnic groups to report insufficient rest or sleep. State estimates of 30 days of insufficient rest or sleep ranged from 7.4% in North Dakota to 19.3% in West Virginia. Health-care providers should consider adding an assessment of chronic rest or sleep insufficiency to routine office visits so they can make needed interventions or referrals to sleep specialists.

  17. How Are Previous Physical Activity and Self-Efficacy Related to Future Physical Activity and Self-Efficacy?

    ERIC Educational Resources Information Center

    David, Prabu; Pennell, Michael L.; Foraker, Randi E.; Katz, Mira L.; Buckworth, Janet; Paskett, Electra D.

    2014-01-01

    Self-efficacy (SE) has been found to be a robust predictor of success in achieving physical activity (PA) goals. While much of the current research has focused on SE as a trait, SE as a state has received less attention. Using day-to-day measurements obtained over 84 days, we examined the relationship between state SE and PA. Postmenopausal women…

  18. Combined PET/MR: The Real Work Has Just Started. Summary Report of the Third International Workshop on PET/MR Imaging; February 17-21, 2014, Tübingen, Germany.

    PubMed

    Bailey, D L; Antoch, G; Bartenstein, P; Barthel, H; Beer, A J; Bisdas, S; Bluemke, D A; Boellaard, R; Claussen, C D; Franzius, C; Hacker, M; Hricak, H; la Fougère, C; Gückel, B; Nekolla, S G; Pichler, B J; Purz, S; Quick, H H; Sabri, O; Sattler, B; Schäfer, J; Schmidt, H; van den Hoff, J; Voss, S; Weber, W; Wehrl, H F; Beyer, T

    2015-06-01

    This paper summarises the proceedings and discussions at the third annual workshop held in Tübingen, Germany, dedicated to the advancement of the technical, scientific and clinical applications of combined PET/MRI systems in humans. Two days of basic scientific and technical instructions with "hands-on" tutorials were followed by 3 days of invited presentations from active researchers in this and associated fields augmented by round-table discussions and dialogue boards with specific themes. These included the use of PET/MRI in paediatric oncology and in adult neurology, oncology and cardiology, the development of multi-parametric analyses, and efforts to standardise PET/MRI examinations to allow pooling of data for evaluating the technology. A poll taken on the final day demonstrated that over 50 % of those present felt that while PET/MRI technology underwent an inevitable slump after its much-anticipated initial launch, it was now entering a period of slow, progressive development, with new key applications emerging. In particular, researchers are focusing on exploiting the complementary nature of the physiological (PET) and biochemical (MRI/MRS) data within the morphological framework (MRI) that these devices can provide. Much of the discussion was summed up on the final day when one speaker commented on the state of PET/MRI: "the real work has just started".

  19. Cost Analysis of Hospitalized Patients with Chronic Obstructive Pulmonary Disease: A State-Level Cross-Sectional Study.

    PubMed

    Torabipour, Amin; Hakim, Ashrafalsadat; Ahmadi Angali, Kambiz; Dolatshah, Marzieh; Yusofzadeh, Maryam

    2016-01-01

    Chronic obstructive pulmonary disease (COPD) is a common disease with important healthcare, social, and economic consequences. The aim of this study was to analyze the costs of hospitalizing patients with COPD. In this state-level cross-sectional study, data from 165 COPD patients who had presented to our hospital between April 1, 2011 and March 31, 2013 were reviewed retrospectively. Patients were eligible for inclusion if they had a diagnosis of COPD [international classification of diseases-10 (ICD-10) code J44]. Costs of COPD patients were calculated by multiplying the amount of services used by the unit cost. Finally, we used multivariate regression analysis to determine predictors of hospital costs. Mean (SD) age of the patients was 68.6 ± 12 years and 65.5% of them were ≥ 65. The mean (SD) and median length of stay (LOS) for patients were 8.5 ± 11.5 and five days [IQR 3; 9], respectively. All hospital cost drivers had significant relationships with LOS, and the mean cost per patient was higher in patients with hospital LOS longer than nine days. Prolonged LOS (LOS > 9 days) involved 830 bed/days. Therefore, the mean cost per each extra day of hospital stay was estimated to be US $115.80. The mean costs per patient with and without hypertension were US $1,422.5 and US $627.4, respectively (P=0.017). Hospitalization and medication costs were the two major cost drivers for patients hospitalized with COPD exacerbation. Duration of hospital stay, history of hypertension, and the number of clinical consultations other were significant predictors associated with hospital cost in patients with COPD.

  20. Persistent effects of prior chronic exposure to corticosterone on reward-related learning and motivation in rodents.

    PubMed

    Olausson, Peter; Kiraly, Drew D; Gourley, Shannon L; Taylor, Jane R

    2013-02-01

    Repeated or prolonged exposure to stress has profound effects on a wide spectrum of behavioral and neurobiological processes and has been associated with the pathophysiology of depression. The multifaceted nature of this disorder includes despair, anhedonia, diminished motivation, and disrupted cognition, and it has been proposed that depression is also associated with reduced reward-motivated learning. We have previously reported that prior chronic corticosterone exposure to mice produces a lasting depressive-like state that can be reversed by chronic antidepressant treatment. In the present study, we tested the effects of prior chronic exposure to corticosterone (50 μg/ml) administered to rats or to mice in drinking water for 14 days followed by dose-tapering over 9 days. The exposure to corticosterone produced lasting deficits in the acquisition of reward-related learning tested on a food-motivated instrumental task conducted 10-20 days after the last day of full dose corticosterone exposure. Rats exposed to corticosterone also displayed reduced responding on a progressive ratio schedule of reinforcement when tested on day 21 after exposure. Amitriptyline (200 mg/ml in drinking water) exposure for 14 days to mice produced the opposite effect, enhancing food-motivated instrumental acquisition and performance. Repeated treatment with amitriptyline (5 mg/kg, intraperitoneally; bid) subsequent to corticosterone exposure also prevented the corticosterone-induced deficits in rats. These results are consistent with aberrant reward-related learning and motivational processes in depressive states and provide new evidence that stress-induced neuroadaptive alterations in cortico-limbic-striatal brain circuits involved in learning and motivation may play a critical role in aspects of mood disorders.

  1. A Comparison of Mortality Following Emergency Laparotomy Between Populations From New York State and England.

    PubMed

    Tan, Benjamin H L; Mytton, Jemma; Al-Khyatt, Waleed; Aquina, Christopher T; Evison, Felicity; Fleming, Fergal J; Griffiths, Ewen; Vohra, Ravinder S

    2017-08-01

    The aim of this study was to compare mortality following emergency laparotomy between populations from New York State and England. Mortality following emergency surgery is a key quality improvement metric in both the United States and UK. Comparison of the all-cause 30-day mortality following emergency laparotomy between populations from New York State and England might identify factors that could improve care. Patient demographics, in-hospital, and 30-day outcomes data were extracted from Hospital Episode Statistics (HES) in England and the New York Statewide Planning and Research Cooperative System (SPARCS) administrative databases for all patients older than 18 years undergoing laparotomy for emergency open bowel surgery between April 2009 and March 2014. The primary outcome measure was all-cause mortality within 30 days of the index laparotomy. Mixed-effects logistic regression was performed to model independent demographic variables against mortality. A one-to-one propensity score matched dataset was created to compare the odd ratios of mortality between the 2 populations. Overall, 137,869 patient records, 85,286 (61.9%) from England and 52,583 (38.1%) from New York State, were extracted. Crude 30-day mortality for patients was significantly higher in the England compared with New York State [11,604 (13.6%) vs 3633 (6.9%) patients, P < 0.001]. Patients undergoing emergency laparotomy in England had significantly higher risk of mortality compared with those in New York State (odds ratio 2.35, confidence interval 2.24-2.46, P < 0.001). The risk of mortality at 30 days is higher following emergency laparotomy in England as compared with New York State despite similar patient groups.

  2. Both trait and state mindfulness predict lower aggressiveness via anger rumination: A multilevel mediation analysis

    PubMed Central

    Eisenlohr-Moul, Tory A.; Peters, Jessica R.; Pond, Richard S.; DeWall, C. Nathan

    2016-01-01

    Trait mindfulness, or the capacity for nonjudgmental, present-centered attention, predicts lower aggression in cross-sectional samples, an effect mediated by reduced anger rumination. Experimental work also implicates state mindfulness (i.e., fluctuations around one's typical mindfulness) in aggression. Despite evidence that both trait and state mindfulness predict lower aggression, their relative impact and their mechanisms remain unclear. Higher trait mindfulness and state increases in mindfulness facets may reduce aggression-related outcomes by (1) limiting the intensity of anger, or (2) limiting rumination on anger experiences. The present study tests two hypotheses: First, that both trait and state mindfulness contribute unique variance to lower aggressiveness, and second, that the impact of both trait and state mindfulness on aggressiveness will be uniquely partially mediated by both anger intensity and anger rumination. 86 participants completed trait measures of mindfulness, anger intensity, and anger rumination, then completed diaries for 35 days assessing mindfulness, anger intensity, anger rumination, anger expression, and self-reported and behavioral aggressiveness. Using multilevel zero-inflated regression, we examined unique contributions of trait and state mindfulness facets to daily anger expression and aggressiveness. We also examined the mediating roles of anger intensity and anger rumination at both trait and state levels. Mindfulness facets predicted anger expression and aggressiveness indirectly through anger rumination after controlling for indirect pathways through anger intensity. Individuals with high or fluctuating aggression may benefit from mindfulness training to reduce both intensity of and rumination on anger. PMID:27429667

  3. Physician Dispensing of Oxycodone and Other Commonly Used Opioids, 2000-2015, United States.

    PubMed

    Mack, Karin Ann; Jones, Christopher McCall; McClure, Roderick John

    2018-05-01

    An average of 91 people in the United States die every day from an opioid-related overdose (including prescription opioids and heroin). The direct dispensing of opioids from health care practitioner offices has been linked to opioid-related harms. The objective of this study is to describe the changing nature of the volume of this type of prescribing at the state level. This descriptive study examines the distribution of opioids by practitioners using 1999-2015 Automation of Reports and Consolidated Orders System data. Analyses were restricted to opioids distributed to practitioners. Amount distributed (morphine milligram equivalents [MMEs]) and number of practitioners are presented. Patterns of distribution to practitioners and the number of practitioners varied markedly by state and changed dramatically over time. Comparing 1999 with 2015, the MME distributed to dispensing practitioners decreased in 16 states and increased in 35. Most notable was the change in Florida, which saw a peak of 8.94 MMEs per 100,000 persons in 2010 (the highest distribution in all states in all years) and a low of 0.08 in 2013. This study presents the first state estimates of office-based dispensing of opioids. Increases in direct dispensing in recent years may indicate a need to monitor this practice and consider whether changes are needed. Using controlled substances data to identify high prescribers and dispensers of opioids, as well as examining overall state trends, is a foundational activity to informing the response to potentially high-risk clinical practices.

  4. Blastocyst transfer in human in vitro fertilization. A solution to the multiple pregnancy epidemic.

    PubMed

    Vidaeff, A C; Racowsky, C; Rayburn, W F

    2000-07-01

    Since the 1950s, the incidence of twin gestation has doubled and the incidence of triplets has increased approximately sevenfold in the United States. Of extreme concern is the fact that many of these multiple pregnancies are iatrogenic: 35% of twin gestations and 77% of higher-order pregnancies are the result of some form of infertility therapy. Anything that can be done to reduce the number of these multiple pregnancies would benefit our patients and society. Great hope is placed on emerging blastocyst technology, which has the potential of achieving higher pregnancy rates per embryo transfer while reducing the risk of multiple pregnancy. We present the evolution of the blastocyst transfer concept and the technical aspects involved. The article also outlines the experience with blastocyst culture and transfer at Brigham and Women's Hospital, Boston, and describes identifiers for application of blastocyst transfer. The number of eight-cell embryos on day 3 is an independent marker for the selection of patients who would benefit from transfer on day 5. With no eight-cell embryos on day 3, 0% and 33% pregnancies resulted from day 5 vs. day 3 transfers, suggesting that these cases would not benefit from day 5 transfer. When at least one eight-cell embryo is available, there is no difference in ongoing pregnancy rates between day 5 and day 3 transfers, but there is a significant decrease in multiple gestations with day 5 transfers.

  5. 2017 Marine Hydrokinetic Instrumentation Workshop Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Driscoll, Frederick R; Mauer, Erik; Rieks, Jeff

    The third Marine Hydrokinetic Instrumentation Workshop was held at Florida Atlantic University's Sea Tech Campus in Dania Beach, Florida, from February 28 to March 1, 2017. The workshop brought together 37 experts in marine energy measurement, testing, and technology development to present and discuss the instrumentation and data-processing needs of the marine energy industry. The workshop was comprised of a plenary session followed by two focused breakout sessions. The half-day plenary session reviewed findings from prior instrumentation workshops, presented research activities that aim to fill previously identified gaps, and had industry experts present the state of the marine energy measurementmore » technologies. This report provides further detail on the workshop, objectives, and findings.« less

  6. Role of the Yakutat collision and upper mantle dynamics in the present-day tectonics of the North America Northern Cordillera

    NASA Astrophysics Data System (ADS)

    Mazzotti, S.; Tarayoun, A.; Marechal, A.; Audet, P.

    2017-12-01

    The Northern Cordillera of North America is a type example of present-day strain distribution across a wide orogeny. Several geodynamic models are proposed to explain this large-scale tectonic activity, with two main end-members: strain transfer from the Yakutat collision zone (orogenic float) and strain transfer from upper mantle convection (lithosphere basal traction). One of the main differences between these is the lithosphere vertical rheology profile: the former requires significant crust - mantle decoupling to allow far field strain transfer, whereas the latter requires a vertically coupled lithosphere. Here we combine recent data across the eastern region of the Northern Cordillera (eastern Alaska, Yukon, western Northwest Territories) to characterize its states of strain rate, stress, and crustal and lithospheric structure, in order to test the role of the Yakutat collision and upper mantle convection in its present-day tectonics. Recent GPS data confirm the radial, east- to northeastward motion of the central Yukon and foreland belt (Mackenzie and Richardson Mountains), albeit at a much lower velocity than previously proposed. This motion is primarily accommodated by E-W to NE-SW shortening, mainly in the foreland belt, and small to near-zero lateral motion on the major Denali and Tintina strike-slip faults. Seismic anisotropy data further suggest that these two major faults, like most of the Yukon Cordillera, have kept their early Cenozoic crustal and upper mantle structures, as shown by the fault-parallel (NW-SE) fast anisotropy orientation. We use these new data, combined with numerical models of strain distribution under various boundary conditions, to provide constraints on the respective role of the Yakutat collision and upper mantle convection in the present-day tectonics. Preliminary results suggest that, whichever the driving mechanism (or combination thereof), the total strain associated with the present-day tectonics must remain small in order to preserve the inherited crustal and mantle fabrics. Such small cumulative strain appears in contradiction with a thin decoupling layer (such as lower crust decoupling in the orogenic float model) and seems more suggestive of distributed shear across a large part of the lithosphere.

  7. Stress-free automatic sleep deprivation using air puffs

    PubMed Central

    Gross, Brooks A.; Vanderheyden, William M.; Urpa, Lea M.; Davis, Devon E.; Fitzpatrick, Christopher J.; Prabhu, Kaustubh; Poe, Gina R.

    2015-01-01

    Background Sleep deprivation via gentle handling is time-consuming and personnel-intensive. New Method We present here an automated sleep deprivation system via air puffs. Implanted EMG and EEG electrodes were used to assess sleep/waking states in six male Sprague-Dawley rats. Blood samples were collected from an implanted intravenous catheter every 4 hours during the 12-hour light cycle on baseline, 8 hours of sleep deprivation via air puffs, and 8 hours of sleep deprivation by gentle handling days. Results The automated system was capable of scoring sleep and waking states as accurately as our offline version (~90% for sleep) and with sufficient speed to trigger a feedback response within an acceptable amount of time (1.76 s). Manual state scoring confirmed normal sleep on the baseline day and sleep deprivation on the two manipulation days (68% decrease in non-REM, 63% decrease in REM, and 74% increase in waking). No significant differences in levels of ACTH and corticosterone (stress hormones indicative of HPA axis activity) were found at any time point between baseline sleep and sleep deprivation via air puffs. Comparison with Existing Method There were no significant differences in ACTH or corticosterone concentrations between sleep deprivation by air puffs and gentle handling over the 8-hour period. Conclusions Our system accurately detects sleep and delivers air puffs to acutely deprive rats of sleep with sufficient temporal resolution during the critical 4-5 h post learning sleep-dependent memory consolidation period. The system is stress-free and a viable alternative to existing sleep deprivation techniques. PMID:26014662

  8. Dopamine and light: dissecting effects on mood and motivational states in women with subsyndromal seasonal affective disorder

    PubMed Central

    Cawley, Elizabeth I.; Park, Sarah; Rot, Marije aan het; Sancton, Kimberley; Benkelfat, Chawki; Young, Simon N.; Boivin, Diane B.; Leyton, Marco

    2013-01-01

    Background Despite evidence that bright light can improve mood, the neurobiology remains poorly understood. Some evidence implicates the catecholamines. In the present study, we measured the effects of transiently decreasing dopamine (DA) synthesis on mood and motivational states in healthy women with mild seasonal mood changes who were tested in either bright or dim light. Methods On 2 test days, participants slept overnight in a light-controlled room. On the morning of each session, half of the participants awoke to gradual increases of bright light, up to 3000 lux, and half to dim light (10 lux). For all participants, DA was reduced on 1 of the test days using the acute phenylalanine/tyrosine depletion (APTD) method; on the other day, they ingested a nutritionally balanced control mixture (BAL). Beginning 4 hours postingestion, participants completed subjective mood questionnaires, psychological tests and a progressive ratio breakpoint task during which they worked for successive units of $5. Results Thirty-two women participated in our study. The APTD lowered mood, agreeableness, energy and the willingness to work for monetary reward. The effects on energy and motivation were independent of light, while the effects on mood and agreeableness were seen in the dim condition only, being prevented by bright light. Limitations Acute phenylalanine/tyrosine depletion might affect systems other than DA. The sample size was small. Conclusion These results suggest that increased DA function may be responsible for some of the beneficial effects of light, while adding to the evidence that the neurobiology of mood and motivational states can be dissociated. PMID:23735584

  9. Stress-free automatic sleep deprivation using air puffs.

    PubMed

    Gross, Brooks A; Vanderheyden, William M; Urpa, Lea M; Davis, Devon E; Fitzpatrick, Christopher J; Prabhu, Kaustubh; Poe, Gina R

    2015-08-15

    Sleep deprivation via gentle handling is time-consuming and personnel-intensive. We present here an automated sleep deprivation system via air puffs. Implanted EMG and EEG electrodes were used to assess sleep/waking states in six male Sprague-Dawley rats. Blood samples were collected from an implanted intravenous catheter every 4h during the 12-h light cycle on baseline, 8h of sleep deprivation via air puffs, and 8h of sleep deprivation by gentle handling days. The automated system was capable of scoring sleep and waking states as accurately as our offline version (∼90% for sleep) and with sufficient speed to trigger a feedback response within an acceptable amount of time (1.76s). Manual state scoring confirmed normal sleep on the baseline day and sleep deprivation on the two manipulation days (68% decrease in non-REM, 63% decrease in REM, and 74% increase in waking). No significant differences in levels of ACTH and corticosterone (stress hormones indicative of HPA axis activity) were found at any time point between baseline sleep and sleep deprivation via air puffs. There were no significant differences in ACTH or corticosterone concentrations between sleep deprivation by air puffs and gentle handling over the 8-h period. Our system accurately detects sleep and delivers air puffs to acutely deprive rats of sleep with sufficient temporal resolution during the critical 4-5h post learning sleep-dependent memory consolidation period. The system is stress-free and a viable alternative to existing sleep deprivation techniques. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Dopamine and light: dissecting effects on mood and motivational states in women with subsyndromal seasonal affective disorder.

    PubMed

    Cawley, Elizabeth I; Park, Sarah; aan het Rot, Marije; Sancton, Kimberley; Benkelfat, Chawki; Young, Simon N; Boivin, Diane B; Leyton, Marco

    2013-11-01

    Despite evidence that bright light can improve mood, the neurobiology remains poorly understood. Some evidence implicates the catecholamines. In the present study, we measured the effects of transiently decreasing dopamine (DA) synthesis on mood and motivational states in healthy women with mild seasonal mood changes who were tested in either bright or dim light. On 2 test days, participants slept overnight in a light-controlled room. On the morning of each session, half of the participants awoke to gradual increases of bright light, up to 3000 lux, and half to dim light (10 lux). For all participants, DA was reduced on 1 of the test days using the acute phenylalanine/tyrosine depletion (APTD) method; on the other day, they ingested a nutritionally balanced control mixture (BAL). Beginning 4 hours postingestion, participants completed subjective mood questionnaires, psychological tests and a progressive ratio breakpoint task during which they worked for successive units of $5. Thirty-two women participated in our study. The APTD lowered mood, agreeableness, energy and the willingness to work for monetary reward. The effects on energy and motivation were independent of light, while the effects on mood and agreeableness were seen in the dim condition only, being prevented by bright light. Acute phenylalanine/tyrosine depletion might affect systems other than DA. The sample size was small. These results suggest that increased DA function may be responsible for some of the beneficial effects of light, while adding to the evidence that the neurobiology of mood and motivational states can be dissociated.

  11. Sleep homeostasis in the female rat during the estrous cycle.

    PubMed

    Schwierin, B; Borbély, A A; Tobler, I

    1998-11-16

    To investigate whether sleep homeostasis in the female rat is modulated by the estrous cycle, the vigilance states, EEG power spectra and cortical temperature (TCRT) were assessed on the basis of 4-day continuous recordings. A regulatory response was elicited by 6-h sleep deprivation (SD) during the proestrous (PRO) and the estrous (EST) day and compared to the baseline recordings. The vigilance states varied across the estrous cycle. In the PRO dark period the amount of sleep was reduced. The decrease in rapid-eye-movement (REM) sleep was already evident towards the end of the preceding light period, and an increased fragmentation of sleep was present throughout PRO. Compared to the other days of the estrous cycle, slow-wave activity (SWA; EEG power density 0.75-4.75 Hz) in nonREM (NREM) sleep was lower in PRO at the end of the light period and in the beginning of the dark period. High-frequency activity (HFA; EEG power density 10.25-25.0 Hz) was increased in the dark period of PRO. The SD performed during the first 6 h of the light period of PRO and EST enhanced SWA in NREM sleep and reduced sleep fragmentation during the subsequent 6 h. The extent and time course of the response to SD did not differ between the two phases of the estrous cycle. It is concluded that despite the marked baseline variations of the vigilance states and the EEG, homeostatic regulation is little affected by the estrous cycle. Copyright 1998 Elsevier Science B.V.

  12. Might astrocytes play a role in maintaining the seizure-prone state?

    PubMed

    Vessal, Mani; Dugani, Chandrasagar B; Solomon, Dianand A; McIntyre Burnham, W; Ivy, Gwen O

    2005-05-24

    The amygdala-kindling model is used to study complex partial epilepsy with secondary generalization. The present study was designed to (A) quantify astrocytic changes in the piriform cortex of amygdala-kindled subjects over time and (B) investigate the role that astrocytes might play in maintaining the seizure-prone state. In Study A, once the experimental subjects reached five stage 5 seizures, stimulation was stopped, and both kindled and control rats were allowed to survive for the interval appropriate to their group (7, 18, 30, or 90 days). Following each interval, the kindled and control animals were given 10 intraperitoneal injections of bromodeoxyuridine (BrdU) and sacrificed 24 h following the last injection. Significantly higher numbers of dividing astrocytes (identified by co-labeling for BrdU and to one of the astrocytic intermediate filament proteins glial fibrillary acidic protein or vimentin) were found in the kindled brains. All kindled groups had significantly higher numbers of double-labeled cells on the side contralateral to the stimulation site, except for those in the 90 day survival group. In Study B, rats were implanted with chemotrodes, were kindled as in Study A, and were subsequently infused with either saline or with L alpha-AA (to lesion astrocytes) during a further 25 stimulations (1/day). L alpha-AA infused rats had significantly diminished levels of behavioral seizures, higher after discharge thresholds, lower after discharge durations, and decreased numbers of double-labeled astrocytes in piriform cortex than did saline infused rats. Together, the data indicate that astrocytes may play a role in maintaining the seizure-prone state.

  13. Study on spoilage capability and VBNC state formation and recovery of Lactobacillus plantarum.

    PubMed

    Liu, Junyan; Li, Lin; Li, Bing; Peters, Brian M; Deng, Yang; Xu, Zhenbo; Shirtliff, Mark E

    2017-09-01

    The present study aimed at investigating the capability of L. plantarum strain BM-LP14723 to enter into and recover from the viable but nonculturable (VBNC) state and to cause beer spoilage. VBNC state was induced by incubating in beer with subculturing or low temperature treatment. Culturable, total, and viable cells numbers were assessed by MRS agar plate counting, acridine orange direct counting, and Live/Dead BacLight bacterial viability kit, respectively. Organic acids concentrations were measured by reversed-phase high performance liquid chromatography. VBNC L. plantarum cells were detected after 189 ± 1.9 days low temperature treatment or 29 ± 0.7 subcultures in beer. The VBNC L. plantarum retained spoilage capability. Addition of catalase is an effective method for the recovery of the VBNC L. plantarum cells. L. plantarum strain BM-LP14723 is capable of entering into and recovery from the VBNC state and maintained spoilage capability. The current study presented that beer-spoilage L. plantarum can hide both in breweries and during transporting and marketing process and thus lead to beer-spoilage incidents. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Work happiness among teachers: a day reconstruction study on the role of self-concordance.

    PubMed

    Tadić, Maja; Bakker, Arnold B; Oerlemans, Wido G M

    2013-12-01

    Self-concordant work motivation arises from one's authentic choices, personal values, and interests. In the present study, we investigated whether self-concordant motivation may fluctuate from one work-related task to the next. On the basis of self-determination theory, we hypothesized that momentary self-concordance buffers the negative impact of momentary work demands on momentary happiness. We developed a modified version of the day reconstruction method to investigate self-concordance, work demands, and happiness during specific work-related tasks on a within-person and within-day level. In total, 132 teachers completed a daily diary on three consecutive work days as well as a background questionnaire. The daily diary resulted in 792 reported work activities and activity-related work demands, self-concordance, and happiness scores. Multilevel analysis showed that-for most work activities-state self-concordant motivation buffered the negative association of work demands with happiness. These findings add to the literature on motivation and well-being by showing that the levels of self-concordance and happiness experienced by employees vary significantly on a within-day level and show a predictable pattern. We discuss theoretical and practical implications of the findings to increase employees' well-being. © 2013.

  15. Recovery time for inflamed middle ear mucosa in chronic otitis media.

    PubMed

    Pakır, Onur; Dinç, Aykut Erdem; Damar, Murat; Akyıldız, İlker; Eliçora, Sultan Şevik; Erdem, Duygu

    2016-01-01

    The present study shows that 2-3 weeks after medical treatment the status of middle ear mucosa in draining ears is similar to that of dry ears for at least 3 months. To measure the time required for an inflamed middle ear mucosa to return into optimal state after appropriate medical treatment in chronic suppurative otitis media (CSOM). To assess optimal timing for elective surgical treatment of draining ears in uncomplicated CSOM. In this prospective study, the Eustachian tube (ET) mucociliary clearance time (MCT) was used as the method to demonstrate the status of middle ear mucosa. In group 1 (28 patients) ET-MCT was measured in ears that were free of drainage for at least 3 months. In Group 2 (21 patients), ET-MCT was measured in draining ears, who responded to 10-14 days medical treatment, at presentation, after 10 days and 1 month. The ET-MCT was 8.63 ± 1.32 min in group 1 and 28.96 ± 8.19 min in group 2 at presentation; and the difference was statistically significant (p < 0.001). The ET-MCT was 14.76 ± 5.11 min after 10 days and 9.31 ± 2.33 min after 1 month in group 2. The ET-MCT was indifferent between groups 1 and 2 after 1 month (p = 0.235).

  16. EXPLORING A 'FLOW' OF HIGHLY ECCENTRIC BINARIES WITH KEPLER

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dong Subo; Katz, Boaz; Socrates, Aristotle

    2013-01-20

    With 16-month of Kepler data, 15 long-period (40-265 days) eclipsing binaries on highly eccentric orbits (minimum e between 0.5 and 0.85) are identified from their closely separated primary and secondary eclipses ({Delta}t{sub I,II} = 3-10 days). These systems confirm the existence of a previously hinted binary population situated near a constant angular momentum track at P(1 - e {sup 2}){sup 3/2} {approx} 15 days, close to the tidal circularization period P{sub circ}. They may be presently migrating due to tidal dissipation and form a steady-state 'flow' ({approx}1% of stars) feeding the close-binary population (few % of stars). If so, futuremore » Kepler data releases will reveal a growing number (dozens) of systems at longer periods, following dN/dlgP {proportional_to} P {sup 1/3} with increasing eccentricities reaching e {yields} 0.98 for P {yields} 1000 days. Radial-velocity follow-up of long-period eclipsing binaries with no secondary eclipses could offer a significantly larger sample. Orders of magnitude more (hundreds) may reveal their presence from periodic 'eccentricity pulses', such as tidal ellipsoidal variations near pericenter passages. Several new few-day-long eccentricity-pulse candidates with long periods (P = 25-80 days) are reported.« less

  17. Biodegradation of tech-hexachlorocyclohexane in a upflow anaerobic sludge blanket (UASB) reactor.

    PubMed

    Bhat, Praveena; Kumar, M Suresh; Mudliar, Sandeep N; Chakrabarti, T

    2006-04-01

    Biodegradability of technical grade hexachlorocyclohexane (tech-HCH) was studied in an upflow anaerobic sludge blanket reactor (UASB) under continuous mode of operation in concentration range of 100-200 mg/l and constant HRT of 48 h. At steady state operation more than 85% removal of tech-HCH (upto 175 mg/l concentration) and complete disappearance of beta-HCH was observed. Kinetic constants in terms of maximum specific tech-HCH utilization rate (k) and half saturation velocity constant (K(L)) were found to be 11.88 mg/g/day and 8.11 mg/g/day, respectively. The tech-HCH degrading seed preparation, UASB reactor startup and degradation in continuous mode of operation of the reactor is presented in this paper.

  18. A numerical model simulation of the regional air pollution meteorology of the greater Chesapeake Bay area - Summer day case study

    NASA Technical Reports Server (NTRS)

    Segal, M.; Pielke, R. A.; Mcnider, R. T.; Mcdougal, D. S.

    1982-01-01

    The mesoscale numerical model of the University of Virginia (UVMM), has been applied to the greater Chesapeake Bay area in order to provide a detailed description of the air pollution meteorology during a typical summer day. This model provides state of the art simulations for land-sea thermally induced circulations. The model-predicted results agree favorably with available observed data. The effects of synoptic flow and sea breeze coupling on air pollution meteorological characteristics in this region, are demonstrated by a spatial and temporal presentation of various model predicted fields. A transport analysis based on predicted wind velocities indicated possible recirculation of pollutants back onto the Atlantic coast due to the sea breeze circulation.

  19. A survey of health care benefits in the apparel industry.

    PubMed

    Moore, W B

    1985-09-01

    Each day as Americans prepare to begin their days, many put on their clothing often without a thought as to how or where it was manufactured. The manufacture of clothing in the United States is a labor intensive industry pressed by competition in foreign countries where labor is abundant and less expensive; therefore, the manufacturers must look for every opportunity to reduce their costs. The survey presented here reviews the health benefit plans in the apparel industry and current initiatives for cost reduction. The results are interesting, for they give the hospital administrator vital information on the types of programs that might be in place in local manufacturers and the method of cost containment expected in this industry.

  20. Moxidectin steady state prior to inoculation protects cats from subsequent, repeated infection with Dirofilaria immitis.

    PubMed

    Little, Susan E; Hostetler, Joe A; Thomas, Jennifer E; Bailey, Keith L; Barrett, Anne W; Gruntmeir, Kaylynn; Gruntmeir, Jeff; Starkey, Lindsay A; Basel, Chris; Blagburn, Byron L

    2015-02-18

    Infection of cats with Dirofilaria immitis causes seroconversion on antibody tests and pulmonary pathology, often without subsequent development of adult heartworms. Consistent administration of topical 10% imidacloprid-1% moxidectin has been shown to result in sustained plasma levels of moxidectin in cats after three to five treatments, a pharmacokinetic behavior known as "steady state". To evaluate the ability of moxidectin at "steady state" to protect cats from subsequent infection with D. immitis, cats (n = 10) were treated with the labeled dose of topical 10% imidacloprid-1% moxidectin for four monthly treatments. Each cat was inoculated with 25 third-stage larvae of D. immitis 7, 14, 21, and 28 days after the last treatment; non-treated cats (n = 9) were inoculated on the same days, serving as infection controls. Blood samples were collected from each cat from 1 month prior to treatment until 7 months after the final inoculation and tested for antibody to, and antigen and microfilaria of, D. immitis. Measurement of serum levels of moxidectin confirmed steady state in treated cats. Cats treated with topical 10% imidacloprid-1% moxidectin prior to trickle inoculation of D. immitis L3 larvae throughout the 28 day post-treatment period remained negative on antibody and antigen tests throughout the study and did not develop gross or histologic lesions characteristic of heartworm infection. A majority of non-treated cats tested antibody positive by 3-4 months post infection (6/9) and, after heat treatment, tested antigen positive by 6-7 months post-infection (5/9). Histologic lesions characteristic of D. immitis infection, including intimal and medial thickening of the pulmonary artery, were present in every cat with D. immitis antibodies (6/6), although adult D. immitis were confirmed in only 5/6 antibody-positive cats at necropsy. Microfilariae were not detected at any time. Taken together, these data indicate that prior treatment with 10% imidacloprid-1% moxidectin protected cats from subsequent infection with D. immitis for 28 days, preventing both formation of a detectable antibody response and development of pulmonary lesions by either immature stages of D. immitis or young adult heartworms.

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