Sample records for present mathematical model

  1. Mathematical Modeling and Pure Mathematics

    ERIC Educational Resources Information Center

    Usiskin, Zalman

    2015-01-01

    Common situations, like planning air travel, can become grist for mathematical modeling and can promote the mathematical ideas of variables, formulas, algebraic expressions, functions, and statistics. The purpose of this article is to illustrate how the mathematical modeling that is present in everyday situations can be naturally embedded in…

  2. Leading Undergraduate Research Projects in Mathematical Modeling

    ERIC Educational Resources Information Center

    Seshaiyer, Padmanabhan

    2017-01-01

    In this article, we provide some useful perspectives and experiences in mentoring students in undergraduate research (UR) in mathematical modeling using differential equations. To engage students in this topic, we present a systematic approach to the creation of rich problems from real-world phenomena; present mathematical models that are derived…

  3. How Ordinary Meaning Underpins the Meaning of Mathematics.

    ERIC Educational Resources Information Center

    Ormell, Christopher

    1991-01-01

    Discusses the meaning of mathematics by looking at its uses in the real world. Offers mathematical modeling as a way to represent mathematical applications in real or potential situations. Presents levels of applicability, modus operandi, relationship to "pure mathematics," and consequences for education for mathematical modeling. (MDH)

  4. The Effect of Teacher Beliefs on Student Competence in Mathematical Modeling--An Intervention Study

    ERIC Educational Resources Information Center

    Mischo, Christoph; Maaß, Katja

    2013-01-01

    This paper presents an intervention study whose aim was to promote teacher beliefs about mathematics and learning mathematics and student competences in mathematical modeling. In the intervention, teachers received written curriculum materials about mathematical modeling. The concept underlying the materials was based on constructivist ideas and…

  5. ASTP ranging system mathematical model

    NASA Technical Reports Server (NTRS)

    Ellis, M. R.; Robinson, L. H.

    1973-01-01

    A mathematical model is presented of the VHF ranging system to analyze the performance of the Apollo-Soyuz test project (ASTP). The system was adapted for use in the ASTP. The ranging system mathematical model is presented in block diagram form, and a brief description of the overall model is also included. A procedure for implementing the math model is presented along with a discussion of the validation of the math model and the overall summary and conclusions of the study effort. Detailed appendices of the five study tasks are presented: early late gate model development, unlock probability development, system error model development, probability of acquisition and model development, and math model validation testing.

  6. Mathematical models of thermoregulation and heat transfer in mammals. A compendium of research

    NASA Technical Reports Server (NTRS)

    Shitzer, A.

    1972-01-01

    An annotated compendium on mathematical modeling of mammal thermoregulation systems is presented. Author abstracts, tables containing the more used mathematical models, solutions to these models, and each thermoregulation mechanism considered are included.

  7. Detecting Strengths and Weaknesses in Learning Mathematics through a Model Classifying Mathematical Skills

    ERIC Educational Resources Information Center

    Karagiannakis, Giannis N.; Baccaglini-Frank, Anna E.; Roussos, Petros

    2016-01-01

    Through a review of the literature on mathematical learning disabilities (MLD) and low achievement in mathematics (LA) we have proposed a model classifying mathematical skills involved in learning mathematics into four domains (Core number, Memory, Reasoning, and Visual-spatial). In this paper we present a new experimental computer-based battery…

  8. Teaching Mathematical Modeling in Mathematics Education

    ERIC Educational Resources Information Center

    Saxena, Ritu; Shrivastava, Keerty; Bhardwaj, Ramakant

    2016-01-01

    Mathematics is not only a subject but it is also a language consisting of many different symbols and relations. Taught as a compulsory subject up the 10th class, students are then able to choose whether or not to study mathematics as a main subject. The present paper discusses mathematical modeling in mathematics education. The article provides…

  9. Three dimensional thermal pollution models. Volume 1: Review of mathematical formulations. [waste heat discharge from power plants and effects on ecosystems

    NASA Technical Reports Server (NTRS)

    Lee, S. S.; Sengupta, S.

    1978-01-01

    A mathematical model package for thermal pollution analyses and prediction is presented. These models, intended as user's manuals, are three dimensional and time dependent using the primitive equation approach. Although they have sufficient generality for application at sites with diverse topographical features; they also present specific instructions regarding data preparation for program execution and sample problems. The mathematical formulation of these models is presented including assumptions, approximations, governing equations, boundary and initial conditions, numerical method of solution, and same results.

  10. Current problems in applied mathematics and mathematical modeling

    NASA Astrophysics Data System (ADS)

    Alekseev, A. S.

    Papers are presented on mathematical modeling noting applications to such fields as geophysics, chemistry, atmospheric optics, and immunology. Attention is also given to models of ocean current fluxes, atmospheric and marine interactions, and atmospheric pollution. The articles include studies of catalytic reactors, models of global climate phenomena, and computer-assisted atmospheric models.

  11. The Relationship between Big Data and Mathematical Modeling: A Discussion in a Mathematical Education Scenario

    ERIC Educational Resources Information Center

    Dalla Vecchia, Rodrigo

    2015-01-01

    This study discusses aspects of the association between Mathematical Modeling (MM) and Big Data in the scope of mathematical education. We present an example of an activity to discuss two ontological factors that involve MM. The first is linked to the modeling stages. The second involves the idea of pedagogical objectives. The main findings…

  12. Mathematical Modelling as a Tool to Understand Cell Self-renewal and Differentiation.

    PubMed

    Getto, Philipp; Marciniak-Czochra, Anna

    2015-01-01

    Mathematical modeling is a powerful technique to address key questions and paradigms in a variety of complex biological systems and can provide quantitative insights into cell kinetics, fate determination and development of cell populations. The chapter is devoted to a review of modeling of the dynamics of stem cell-initiated systems using mathematical methods of ordinary differential equations. Some basic concepts and tools for cell population dynamics are summarized and presented as a gentle introduction to non-mathematicians. The models take into account different plausible mechanisms regulating homeostasis. Two mathematical frameworks are proposed reflecting, respectively, a discrete (punctuated by division events) and a continuous character of transitions between differentiation stages. Advantages and constraints of the mathematical approaches are presented on examples of models of blood systems and compared to patients data on healthy hematopoiesis.

  13. Transmission Dinamics Model Of Dengue Fever

    NASA Astrophysics Data System (ADS)

    Debora; Rendy; Rahmi

    2018-01-01

    Dengue fever is an endemic disease that is transmitted through the Aedes aegypti mosquito vector. The disease is present in more than 100 countries in America, Africa, and Asia, especially tropical countries. Differential equations can be used to represent the spread of dengue virus occurring in time intervals and model in the form of mathematical models. The mathematical model in this study tries to represent the spread of dengue fever based on the data obtained and the assumptions used. The mathematical model used is a mathematical model consisting of Susceptible (S), Infected (I), Viruses (V) subpopulations. The SIV mathematical model is then analyzed to see the solution behaviour of the system.

  14. Scaffolding Mathematical Modelling with a Solution Plan

    ERIC Educational Resources Information Center

    Schukajlow, Stanislaw; Kolter, Jana; Blum, Werner

    2015-01-01

    In the study presented in this paper, we examined the possibility to scaffold mathematical modelling with strategies. The strategies were prompted using an instrument called "solution plan" as a scaffold. The effects of this step by step instrument on mathematical modelling competency and on self-reported strategies were tested using…

  15. Mathematical Modeling and Computational Thinking

    ERIC Educational Resources Information Center

    Sanford, John F.; Naidu, Jaideep T.

    2017-01-01

    The paper argues that mathematical modeling is the essence of computational thinking. Learning a computer language is a valuable assistance in learning logical thinking but of less assistance when learning problem-solving skills. The paper is third in a series and presents some examples of mathematical modeling using spreadsheets at an advanced…

  16. Computational modeling of the cell-autonomous mammalian circadian oscillator.

    PubMed

    Podkolodnaya, Olga A; Tverdokhleb, Natalya N; Podkolodnyy, Nikolay L

    2017-02-24

    This review summarizes various mathematical models of cell-autonomous mammalian circadian clock. We present the basics necessary for understanding of the cell-autonomous mammalian circadian oscillator, modern experimental data essential for its reconstruction and some special problems related to the validation of mathematical circadian oscillator models. This work compares existing mathematical models of circadian oscillator and the results of the computational studies of the oscillating systems. Finally, we discuss applications of the mathematical models of mammalian circadian oscillator for solving specific problems in circadian rhythm biology.

  17. Conceptualization of Approaches and Thought Processes Emerging in Validating of Model in Mathematical Modeling in Technology Aided Environment

    ERIC Educational Resources Information Center

    Hidiroglu, Çaglar Naci; Bukova Güzel, Esra

    2013-01-01

    The aim of the present study is to conceptualize the approaches displayed for validation of model and thought processes provided in mathematical modeling process performed in technology-aided learning environment. The participants of this grounded theory study were nineteen secondary school mathematics student teachers. The data gathered from the…

  18. Near Identifiability of Dynamical Systems

    NASA Technical Reports Server (NTRS)

    Hadaegh, F. Y.; Bekey, G. A.

    1987-01-01

    Concepts regarding approximate mathematical models treated rigorously. Paper presents new results in analysis of structural identifiability, equivalence, and near equivalence between mathematical models and physical processes they represent. Helps establish rigorous mathematical basis for concepts related to structural identifiability and equivalence revealing fundamental requirements, tacit assumptions, and sources of error. "Structural identifiability," as used by workers in this field, loosely translates as meaning ability to specify unique mathematical model and set of model parameters that accurately predict behavior of corresponding physical system.

  19. Bridging the Gulf between Formal Calculus and Physical Reasoning.

    ERIC Educational Resources Information Center

    Van Der Meer, A.

    1980-01-01

    Some ways to link calculus instruction with the mathematical models used in physics courses are presented. The activity of modelling is presented as a major tool in synchronizing physics and mathematics instruction in undergraduate engineering programs. (MP)

  20. Mathematical Modelling Research in Turkey: A Content Analysis Study

    ERIC Educational Resources Information Center

    Çelik, H. Coskun

    2017-01-01

    The aim of the present study was to examine the mathematical modelling studies done between 2004 and 2015 in Turkey and to reveal their tendencies. Forty-nine studies were selected using purposeful sampling based on the term, "mathematical modelling" with Higher Education Academic Search Engine. They were analyzed with content analysis.…

  1. Explorations in Elementary Mathematical Modeling

    ERIC Educational Resources Information Center

    Shahin, Mazen

    2010-01-01

    In this paper we will present the methodology and pedagogy of Elementary Mathematical Modeling as a one-semester course in the liberal arts core. We will focus on the elementary models in finance and business. The main mathematical tools in this course are the difference equations and matrix algebra. We also integrate computer technology and…

  2. How High Is the Tramping Track? Mathematising and Applying in a Calculus Model-Eliciting Activity

    ERIC Educational Resources Information Center

    Yoon, Caroline; Dreyfus, Tommy; Thomas, Michael O. J.

    2010-01-01

    Two complementary processes involved in mathematical modelling are mathematising a realistic situation and applying a mathematical technique to a given realistic situation. We present and analyse work from two undergraduate students and two secondary school teachers who engaged in both processes during a mathematical modelling task that required…

  3. Using TI-Nspire in a Modelling Teacher's Training Course

    ERIC Educational Resources Information Center

    Flores, Ángel Homero; Gómez, Adriana; Chávez, Xochitl

    2015-01-01

    Using Mathematical Modelling has become a useful tool in teaching-learning mathematics at all levels. This is so because mathematical objects are seen from their very applications, giving them meaning from the beginning. In this paper we present some details on the development of a teacher's training course called Modelling in the Teaching of…

  4. The (Mathematical) Modeling Process in Biosciences.

    PubMed

    Torres, Nestor V; Santos, Guido

    2015-01-01

    In this communication, we introduce a general framework and discussion on the role of models and the modeling process in the field of biosciences. The objective is to sum up the common procedures during the formalization and analysis of a biological problem from the perspective of Systems Biology, which approaches the study of biological systems as a whole. We begin by presenting the definitions of (biological) system and model. Particular attention is given to the meaning of mathematical model within the context of biology. Then, we present the process of modeling and analysis of biological systems. Three stages are described in detail: conceptualization of the biological system into a model, mathematical formalization of the previous conceptual model and optimization and system management derived from the analysis of the mathematical model. All along this work the main features and shortcomings of the process are analyzed and a set of rules that could help in the task of modeling any biological system are presented. Special regard is given to the formative requirements and the interdisciplinary nature of this approach. We conclude with some general considerations on the challenges that modeling is posing to current biology.

  5. Turbine Engine Mathematical Model Validation

    DTIC Science & Technology

    1976-12-01

    AEDC-TR-76-90 ~Ec i ? Z985 TURBINE ENGINE MATHEMATICAL MODEL VALIDATION ENGINE TEST FACILITY ARNOLD ENGINEERING DEVELOPMENT CENTER AIR FORCE...i f n e c e s e a ~ ~ d i den t i f y by b l ock number) YJI01-GE-100 engine turbine engines mathematical models computations mathematical...report presents and discusses the results of an investigation to develop a rationale and technique for the validation of turbine engine steady-state

  6. [Representation and mathematical analysis of human crystalline lens].

    PubMed

    Tălu, Stefan; Giovanzana, Stefano; Tălu, Mihai

    2011-01-01

    The surface of human crystalline lens can be described and analyzed using mathematical models based on parametric representations, used in biomechanical studies and 3D solid modeling of the lens. The mathematical models used in lens biomechanics allow the study and the behavior of crystalline lens on variables and complex dynamic loads. Also, the lens biomechanics has the potential to improve the results in the development of intraocular lenses and cataract surgery. The paper presents the most representative mathematical models currently used for the modeling of human crystalline lens, both optically and biomechanically.

  7. Mathematical Modeling and Analysis of a Wide Bandwidth Bipolar Power Supply for the Fast Correctors in the APS Upgrade

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Song, Byeong M.; Wang, Ju

    This paper presents the mathematical modeling and analysis of a wide bandwidth bipolar power supply for the fast correctors in the APS Upgrade. A wide bandwidth current regulator with a combined PI and phase-lead compensator has been newly proposed, analyzed, and simulated through both a mathematical model and a physical electronic circuit model using MATLAB and PLECS. The proposed regulator achieves a bandwidth with a -1.23dB attenuation and a 32.40° phase-delay at 10 kHz for a small signal less than 1% of the DC scale. The mathematical modeling and design, simulation results of a fast corrector power supply control systemmore » are presented in this paper.« less

  8. UAH mathematical model of the variable polarity plasma ARC welding system calculation

    NASA Technical Reports Server (NTRS)

    Hung, R. J.

    1994-01-01

    Significant advantages of Variable Polarity Plasma Arc (VPPA) welding process include faster welding, fewer repairs, less joint preparation, reduced weldment distortion, and absence of porosity. A mathematical model is presented to analyze the VPPA welding process. Results of the mathematical model were compared with the experimental observation accomplished by the GDI team.

  9. Students' Mathematical Modeling of Motion

    ERIC Educational Resources Information Center

    Marshall, Jill A.; Carrejo, David J.

    2008-01-01

    We present results of an investigation of university students' development of mathematical models of motion in a physical science course for preservice teachers and graduate students in science and mathematics education. Although some students were familiar with the standard concepts of position, velocity, and acceleration from physics classes,…

  10. Development of mathematical models of environmental physiology

    NASA Technical Reports Server (NTRS)

    Stolwijk, J. A. J.; Mitchell, J. W.; Nadel, E. R.

    1971-01-01

    Selected articles concerned with mathematical or simulation models of human thermoregulation are presented. The articles presented include: (1) development and use of simulation models in medicine, (2) model of cardio-vascular adjustments during exercise, (3) effective temperature scale based on simple model of human physiological regulatory response, (4) behavioral approach to thermoregulatory set point during exercise, and (5) importance of skin temperature in sweat regulation.

  11. Transient Mathematical Modeling for Liquid Rocket Engine Systems: Methods, Capabilities, and Experience

    NASA Technical Reports Server (NTRS)

    Seymour, David C.; Martin, Michael A.; Nguyen, Huy H.; Greene, William D.

    2005-01-01

    The subject of mathematical modeling of the transient operation of liquid rocket engines is presented in overview form from the perspective of engineers working at the NASA Marshall Space Flight Center. The necessity of creating and utilizing accurate mathematical models as part of liquid rocket engine development process has become well established and is likely to increase in importance in the future. The issues of design considerations for transient operation, development testing, and failure scenario simulation are discussed. An overview of the derivation of the basic governing equations is presented along with a discussion of computational and numerical issues associated with the implementation of these equations in computer codes. Also, work in the field of generating usable fluid property tables is presented along with an overview of efforts to be undertaken in the future to improve the tools use for the mathematical modeling process.

  12. Transient Mathematical Modeling for Liquid Rocket Engine Systems: Methods, Capabilities, and Experience

    NASA Technical Reports Server (NTRS)

    Martin, Michael A.; Nguyen, Huy H.; Greene, William D.; Seymout, David C.

    2003-01-01

    The subject of mathematical modeling of the transient operation of liquid rocket engines is presented in overview form from the perspective of engineers working at the NASA Marshall Space Flight Center. The necessity of creating and utilizing accurate mathematical models as part of liquid rocket engine development process has become well established and is likely to increase in importance in the future. The issues of design considerations for transient operation, development testing, and failure scenario simulation are discussed. An overview of the derivation of the basic governing equations is presented along with a discussion of computational and numerical issues associated with the implementation of these equations in computer codes. Also, work in the field of generating usable fluid property tables is presented along with an overview of efforts to be undertaken in the future to improve the tools use for the mathematical modeling process.

  13. The World According to Malthus and Volterra: The Mathematical Theory of the Struggle for Existence.

    ERIC Educational Resources Information Center

    Bogdanov, Constantine

    1992-01-01

    Discusses the mathematical model presented by Vito Volterra to describe the dynamics of population density. Discusses the predator prey relationship, presents an computer simulated model from marine life involving sharks and mackerels, and discusses ecological chaos. (MDH)

  14. Mathematics Models in Chemistry--An Innovation for Non-Mathematics and Non-Science Majors

    ERIC Educational Resources Information Center

    Rash, Agnes M.; Zurbach, E. Peter

    2004-01-01

    The intention of this article is to present a year-long interdisciplinary course, Mathematical Models in Chemistry. The course is comprised of eleven units, each of which has both a mathematical and a chemical component. A syllabus of the course is given and the format of the class is explained. The interaction of the professors and the content is…

  15. A School-Based Professional Development Programme for Teachers of Mathematical Modelling in Singapore

    ERIC Educational Resources Information Center

    Tan, Liang Soon; Ang, Keng Cheng

    2016-01-01

    A school-based professional development programme (SBPD) aimed at developing secondary school mathematics teachers' competencies to teach mathematical modelling in Singapore is presented and evaluated in this article. The SBPD is characterized by two key features--content elements to develop teachers' knowledge and skills, and transformative…

  16. Mathematical Modeling Approaches in Plant Metabolomics.

    PubMed

    Fürtauer, Lisa; Weiszmann, Jakob; Weckwerth, Wolfram; Nägele, Thomas

    2018-01-01

    The experimental analysis of a plant metabolome typically results in a comprehensive and multidimensional data set. To interpret metabolomics data in the context of biochemical regulation and environmental fluctuation, various approaches of mathematical modeling have been developed and have proven useful. In this chapter, a general introduction to mathematical modeling is presented and discussed in context of plant metabolism. A particular focus is laid on the suitability of mathematical approaches to functionally integrate plant metabolomics data in a metabolic network and combine it with other biochemical or physiological parameters.

  17. Mathematical models in simulation process in rehabilitation of persons with disabilities

    NASA Astrophysics Data System (ADS)

    Gorie, Nina; Dolga, Valer; Mondoc, Alina

    2012-11-01

    The problems of people with disability are varied. A disability may be physical, cognitive, mental, sensory, emotional, developmental or some combination of these. The major disabilities which can appear in people's lives are: the blindness, the deafness, the limb-girdle muscular dystrophy, the orthopedic impairment, the visual impairment. A disability is an umbrella term, covering impairments, activity limitations and participation restrictions. A disability may occur during a person's lifetime or may be present from birth. The authors conclude that some of these disabilities like physical, cognitive, mental, sensory, emotional, developmental can be rehabilitated. Starting from this state of affairs the authors present briefly the possibility of using certain mechatronic systems for rehabilitation of persons with different disabilities. The authors focus their presentation on alternative calling the Stewart platform in order to achieve the proposed goal. The authors present a mathematical model of systems theory approach under the parallel system and described its contents can. The authors analyze in a meaningful mathematical model describing the procedure of rehabilitation process. From the affected function biomechanics and taking into account medical recommendations the authors illustrate the mathematical models of rehabilitation work. The authors assemble a whole mathematical model of parallel structure and the rehabilitation process and making simulation and highlighting the results estimated. The authors present in the end work the results envisaged in the end analysis work, conclusions and steps for future work program..

  18. The (Mathematical) Modeling Process in Biosciences

    PubMed Central

    Torres, Nestor V.; Santos, Guido

    2015-01-01

    In this communication, we introduce a general framework and discussion on the role of models and the modeling process in the field of biosciences. The objective is to sum up the common procedures during the formalization and analysis of a biological problem from the perspective of Systems Biology, which approaches the study of biological systems as a whole. We begin by presenting the definitions of (biological) system and model. Particular attention is given to the meaning of mathematical model within the context of biology. Then, we present the process of modeling and analysis of biological systems. Three stages are described in detail: conceptualization of the biological system into a model, mathematical formalization of the previous conceptual model and optimization and system management derived from the analysis of the mathematical model. All along this work the main features and shortcomings of the process are analyzed and a set of rules that could help in the task of modeling any biological system are presented. Special regard is given to the formative requirements and the interdisciplinary nature of this approach. We conclude with some general considerations on the challenges that modeling is posing to current biology. PMID:26734063

  19. How to build a course in mathematical-biological modeling: content and processes for knowledge and skill.

    PubMed

    Hoskinson, Anne-Marie

    2010-01-01

    Biological problems in the twenty-first century are complex and require mathematical insight, often resulting in mathematical models of biological systems. Building mathematical-biological models requires cooperation among biologists and mathematicians, and mastery of building models. A new course in mathematical modeling presented the opportunity to build both content and process learning of mathematical models, the modeling process, and the cooperative process. There was little guidance from the literature on how to build such a course. Here, I describe the iterative process of developing such a course, beginning with objectives and choosing content and process competencies to fulfill the objectives. I include some inductive heuristics for instructors seeking guidance in planning and developing their own courses, and I illustrate with a description of one instructional model cycle. Students completing this class reported gains in learning of modeling content, the modeling process, and cooperative skills. Student content and process mastery increased, as assessed on several objective-driven metrics in many types of assessments.

  20. Elementary Teachers Integrate Music Activities into Regular Mathematics Lessons: Effects on Students' Mathematical Abilities

    ERIC Educational Resources Information Center

    An, Song; Capraro, Mary Margaret; Tillman, Daniel A.

    2013-01-01

    This article presents exploratory research investigating the way teachers integrate music into their regular mathematics lessons as well as the effects of music-mathematics interdisciplinary lessons on elementary school students' mathematical abilities of modeling, strategy and application. Two teachers and two classes of first grade and third…

  1. Explorations in the Modeling of the Learning of Mathematics.

    ERIC Educational Resources Information Center

    Fuson, Karen C., Ed.; And Others

    Eleven research reports in the area of models of learning mathematics are presented in this publication of the Mathematics Education Reports series. The papers represent a mixture of theories, viewpoints, and references to other areas. Content areas addressed range from preschool to college levels. All the papers are concerned with the learning of…

  2. Mathematical Models for Doppler Measurements

    NASA Technical Reports Server (NTRS)

    Lear, William M.

    1987-01-01

    Error analysis increases precision of navigation. Report presents improved mathematical models of analysis of Doppler measurements and measurement errors of spacecraft navigation. To take advantage of potential navigational accuracy of Doppler measurements, precise equations relate measured cycle count to position and velocity. Drifts and random variations in transmitter and receiver oscillator frequencies taken into account. Mathematical models also adapted to aircraft navigation, radar, sonar, lidar, and interferometry.

  3. The Mathematics of Medical Imaging in the Classroom.

    ERIC Educational Resources Information Center

    Funkhouser, Charles P.; Jafari, Farhad; Eubank, William B.

    2002-01-01

    Presents an integrated exposition of aspects of secondary school mathematics and a medical science specialty. Reviews clinical medical practice and theoretical and empirical literature in mathematics education and radiology to develop and pilot model integrative classroom topics and activities. Suggests mathematical applications in numeration and…

  4. A Snowflake Project: Calculating, Analyzing, and Optimizing with the Koch Snowflake.

    ERIC Educational Resources Information Center

    Bolte, Linda A.

    2002-01-01

    Presents a project that addresses several components of the Algebra and Communication Standards for Grades 9-12 presented in Principles and Standards for School Mathematics (NCTM, 2000). Describes doing mathematical modeling and using the language of mathematics to express a recursive relationship in the perimeter and area of the Koch snowflake.…

  5. Engaging Life-Sciences Students with Mathematical Models: Does Authenticity Help?

    ERIC Educational Resources Information Center

    Poladian, Leon

    2013-01-01

    Compulsory mathematics service units for the life sciences present unique challenges: even students who learn some specific skills maintain a negative attitude to mathematics and do not see the relevance of the unit towards their degree. The focus on authentic content and the presentation and teaching of global or qualitative methods before…

  6. A new adaptive estimation method of spacecraft thermal mathematical model with an ensemble Kalman filter

    NASA Astrophysics Data System (ADS)

    Akita, T.; Takaki, R.; Shima, E.

    2012-04-01

    An adaptive estimation method of spacecraft thermal mathematical model is presented. The method is based on the ensemble Kalman filter, which can effectively handle the nonlinearities contained in the thermal model. The state space equations of the thermal mathematical model is derived, where both temperature and uncertain thermal characteristic parameters are considered as the state variables. In the method, the thermal characteristic parameters are automatically estimated as the outputs of the filtered state variables, whereas, in the usual thermal model correlation, they are manually identified by experienced engineers using trial-and-error approach. A numerical experiment of a simple small satellite is provided to verify the effectiveness of the presented method.

  7. The art of fault-tolerant system reliability modeling

    NASA Technical Reports Server (NTRS)

    Butler, Ricky W.; Johnson, Sally C.

    1990-01-01

    A step-by-step tutorial of the methods and tools used for the reliability analysis of fault-tolerant systems is presented. Emphasis is on the representation of architectural features in mathematical models. Details of the mathematical solution of complex reliability models are not presented. Instead the use of several recently developed computer programs--SURE, ASSIST, STEM, PAWS--which automate the generation and solution of these models is described.

  8. Early Mathematics Fluency with CCSSM

    ERIC Educational Resources Information Center

    Matney, Gabriel T.

    2014-01-01

    To develop second-grade students' confidence and ease, this author presents examples of learning tasks (Number of the Day, Word Problem Solving, and Modeling New Mathematical Ideas) that align with Common Core State Standards for Mathematics and that build mathematical fluency to promote students' creative expression of mathematical…

  9. A Case Study on Pre-Service Secondary School Mathematics Teachers' Cognitive-Metacognitive Behaviours in Mathematical Modelling Process

    ERIC Educational Resources Information Center

    Sagirli, Meryem Özturan

    2016-01-01

    The aim of the present study is to investigate pre-service secondary mathematics teachers' cognitive-metacognitive behaviours during the mathematical problem-solving process considering class level. The study, in which the case study methodology was employed, was carried out with eight pre-service mathematics teachers, enrolled at a university in…

  10. Categorical Working Memory Representations are used in Delayed Estimation of Continuous Colors

    PubMed Central

    Hardman, Kyle O; Vergauwe, Evie; Ricker, Timothy J

    2016-01-01

    In the last decade, major strides have been made in understanding visual working memory through mathematical modeling of color production responses. In the delayed color estimation task (Wilken & Ma, 2004), participants are given a set of colored squares to remember and a few seconds later asked to reproduce those colors by clicking on a color wheel. The degree of error in these responses is characterized with mathematical models that estimate working memory precision and the proportion of items remembered by participants. A standard mathematical model of color memory assumes that items maintained in memory are remembered through memory for precise details about the particular studied shade of color. We contend that this model is incomplete in its present form because no mechanism is provided for remembering the coarse category of a studied color. In the present work we remedy this omission and present a model of visual working memory that includes both continuous and categorical memory representations. In two experiments we show that our new model outperforms this standard modeling approach, which demonstrates that categorical representations should be accounted for by mathematical models of visual working memory. PMID:27797548

  11. Categorical working memory representations are used in delayed estimation of continuous colors.

    PubMed

    Hardman, Kyle O; Vergauwe, Evie; Ricker, Timothy J

    2017-01-01

    In the last decade, major strides have been made in understanding visual working memory through mathematical modeling of color production responses. In the delayed color estimation task (Wilken & Ma, 2004), participants are given a set of colored squares to remember, and a few seconds later asked to reproduce those colors by clicking on a color wheel. The degree of error in these responses is characterized with mathematical models that estimate working memory precision and the proportion of items remembered by participants. A standard mathematical model of color memory assumes that items maintained in memory are remembered through memory for precise details about the particular studied shade of color. We contend that this model is incomplete in its present form because no mechanism is provided for remembering the coarse category of a studied color. In the present work, we remedy this omission and present a model of visual working memory that includes both continuous and categorical memory representations. In 2 experiments, we show that our new model outperforms this standard modeling approach, which demonstrates that categorical representations should be accounted for by mathematical models of visual working memory. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  12. Skimming and Skipping Stones

    ERIC Educational Resources Information Center

    Humble, Steve

    2007-01-01

    This article presents an example of skimming and skipping stone motion in mathematical terms available to students studying A-level mathematics. The theory developed in the article postulates a possible mathematical model that is verified by experimental results.

  13. Goddard trajectory determination subsystem: Mathematical specifications

    NASA Technical Reports Server (NTRS)

    Wagner, W. E. (Editor); Velez, C. E. (Editor)

    1972-01-01

    The mathematical specifications of the Goddard trajectory determination subsystem of the flight dynamics system are presented. These specifications include the mathematical description of the coordinate systems, dynamic and measurement model, numerical integration techniques, and statistical estimation concepts.

  14. A Methodology for Instructional Design in Mathematics--With the Generic and Epistemic Student at the Centre

    ERIC Educational Resources Information Center

    Strømskag, Heidi

    2017-01-01

    This theoretical paper presents a methodology for instructional design in mathematics. It is a theoretical analysis of a proposed model for instructional design, where tasks are embedded in situations that preserve meaning with respect to particular pieces of mathematical knowledge. The model is applicable when there is an intention of teaching…

  15. A Mathematical Model of a Simple Amplifier Using a Ferroelectric Transistor

    NASA Technical Reports Server (NTRS)

    Sayyah, Rana; Hunt, Mitchell; MacLeod, Todd C.; Ho, Fat D.

    2009-01-01

    This paper presents a mathematical model characterizing the behavior of a simple amplifier using a FeFET. The model is based on empirical data and incorporates several variables that affect the output, including frequency, load resistance, and gate-to-source voltage. Since the amplifier is the basis of many circuit configurations, a mathematical model that describes the behavior of a FeFET-based amplifier will help in the integration of FeFETs into many other circuits.

  16. Three-phase boundary length in solid-oxide fuel cells: A mathematical model

    NASA Astrophysics Data System (ADS)

    Janardhanan, Vinod M.; Heuveline, Vincent; Deutschmann, Olaf

    A mathematical model to calculate the volume specific three-phase boundary length in the porous composite electrodes of solid-oxide fuel cell is presented. The model is exclusively based on geometrical considerations accounting for porosity, particle diameter, particle size distribution, and solids phase distribution. Results are presented for uniform particle size distribution as well as for non-uniform particle size distribution.

  17. Mathematical Models for Immunology: Current State of the Art and Future Research Directions.

    PubMed

    Eftimie, Raluca; Gillard, Joseph J; Cantrell, Doreen A

    2016-10-01

    The advances in genetics and biochemistry that have taken place over the last 10 years led to significant advances in experimental and clinical immunology. In turn, this has led to the development of new mathematical models to investigate qualitatively and quantitatively various open questions in immunology. In this study we present a review of some research areas in mathematical immunology that evolved over the last 10 years. To this end, we take a step-by-step approach in discussing a range of models derived to study the dynamics of both the innate and immune responses at the molecular, cellular and tissue scales. To emphasise the use of mathematics in modelling in this area, we also review some of the mathematical tools used to investigate these models. Finally, we discuss some future trends in both experimental immunology and mathematical immunology for the upcoming years.

  18. Gender Differences in Mathematics: Does the Story Need to Be Rewritten?

    ERIC Educational Resources Information Center

    Brunner, Martin; Krauss, Stefan; Kunter, Mareike

    2008-01-01

    Empirical studies of high school mathematics typically report small gender differences in favor of boys. The present article challenges this established finding by comparing two competing structural conceptions of mathematical ability. The standard model assumes mathematical ability alone to account for the interindividual differences observed on…

  19. Inssues for Consideration by Mathematics Educators: Selected Papers.

    ERIC Educational Resources Information Center

    Denmark, Tom, Ed.

    This set of papers, selected from presentations at the Fourth and Fifth Annual Conferences of the Research Council for Diagnostic and Prescriptive Mathematics, are of primary interest to mathematics educators. In the first paper, Romberg describes a model for diagnosing mathematical learning difficulties which extends the diagnostic process beyond…

  20. Identifiability Of Systems With Modeling Errors

    NASA Technical Reports Server (NTRS)

    Hadaegh, Yadolah " fred" ; Bekey, George A.

    1988-01-01

    Advances in theory of modeling errors reported. Recent paper on errors in mathematical models of deterministic linear or weakly nonlinear systems. Extends theoretical work described in NPO-16661 and NPO-16785. Presents concrete way of accounting for difference in structure between mathematical model and physical process or system that it represents.

  1. AIDS Epidemiological models

    NASA Astrophysics Data System (ADS)

    Rahmani, Fouad Lazhar

    2010-11-01

    The aim of this paper is to present mathematical modelling of the spread of infection in the context of the transmission of the human immunodeficiency virus (HIV) and the acquired immune deficiency syndrome (AIDS). These models are based in part on the models suggested in the field of th AIDS mathematical modelling as reported by ISHAM [6].

  2. A Unified Mathematical Definition of Classical Information Retrieval.

    ERIC Educational Resources Information Center

    Dominich, Sandor

    2000-01-01

    Presents a unified mathematical definition for the classical models of information retrieval and identifies a mathematical structure behind relevance feedback. Highlights include vector information retrieval; probabilistic information retrieval; and similarity information retrieval. (Contains 118 references.) (Author/LRW)

  3. Achilles and the tortoise: Some caveats to mathematical modeling in biology.

    PubMed

    Gilbert, Scott F

    2018-01-31

    Mathematical modeling has recently become a much-lauded enterprise, and many funding agencies seek to prioritize this endeavor. However, there are certain dangers associated with mathematical modeling, and knowledge of these pitfalls should also be part of a biologist's training in this set of techniques. (1) Mathematical models are limited by known science; (2) Mathematical models can tell what can happen, but not what did happen; (3) A model does not have to conform to reality, even if it is logically consistent; (4) Models abstract from reality, and sometimes what they eliminate is critically important; (5) Mathematics can present a Platonic ideal to which biologically organized matter strives, rather than a trial-and-error bumbling through evolutionary processes. This "Unity of Science" approach, which sees biology as the lowest physical science and mathematics as the highest science, is part of a Western belief system, often called the Great Chain of Being (or Scala Natura), that sees knowledge emerge as one passes from biology to chemistry to physics to mathematics, in an ascending progression of reason being purification from matter. This is also an informal model for the emergence of new life. There are now other informal models for integrating development and evolution, but each has its limitations. Copyright © 2018 Elsevier Ltd. All rights reserved.

  4. Integrated STEM Assessment Model

    ERIC Educational Resources Information Center

    Bicer, Ali; Capraro, Robert M.; Capraro, Mary M.

    2017-01-01

    Previous research identified a strong correlation between mathematics and science performance albeit for small samples of students. Even though there was a high correlation between mathematics and science performance, researchers examining students' STEM achievement investigated mathematics and science achievement separately. The present study…

  5. Identification of mathematical model of human breathing in system “Artificial lungs – self-contained breathing apparatus”

    NASA Astrophysics Data System (ADS)

    Onevsky, P. M.; Onevsky, M. P.; Pogonin, V. A.

    2018-03-01

    The structure and mathematical models of the main subsystems of the control system of the “Artificial Lungs” are presented. This structure implements the process of imitation of human external respiration in the system “Artificial lungs - self-contained breathing apparatus”. A presented algorithm for parametric identification of the model is based on spectral operators, which allows using it in real time.

  6. A Unique Large-Scale Undergraduate Research Experience in Molecular Systems Biology for Non-Mathematics Majors

    ERIC Educational Resources Information Center

    Kappler, Ulrike; Rowland, Susan L.; Pedwell, Rhianna K.

    2017-01-01

    Systems biology is frequently taught with an emphasis on mathematical modeling approaches. This focus effectively excludes most biology, biochemistry, and molecular biology students, who are not mathematics majors. The mathematical focus can also present a misleading picture of systems biology, which is a multi-disciplinary pursuit requiring…

  7. Teachers' Temporary Support and Worked-Out Examples as Elements of Scaffolding in Mathematical Modeling

    ERIC Educational Resources Information Center

    Tropper, Natalie; Leiss, Dominik; Hänze, Martin

    2015-01-01

    Empirical findings show that students have manifold difficulties when dealing with mathematical modeling problems. Accordingly, approaches for supporting students in modeling-based learning environments have to be investigated. In the research presented here, we adopted a scaffolding perspective on teaching modeling with the aim of both providing…

  8. Mathematical modeling of fluxgate magnetic gradiometers

    NASA Astrophysics Data System (ADS)

    Milovzorov, D. G.; Yasoveev, V. Kh.

    2017-07-01

    Issues of designing fluxgate magnetic gradiometers are considered. The areas of application of fluxgate magnetic gradiometers are determined. The structure and layout of a two-component fluxgate magnetic gradiometer are presented. It is assumed that the fluxgates are strictly coaxial in the gradiometer body. Elements of the classical approach to the mathematical modeling of the spatial arrangement of solids are considered. The bases of the gradiometer body and their transformations during spatial displacement of the gradiometer are given. The problems of mathematical modeling of gradiometers are formulated, basic mathematical models of a two-component fluxgate gradiometer are developed, and the mathematical models are analyzed. A computer experiment was performed. Difference signals from the gradiometer fluxgates for the vertical and horizontal position of the gradiometer body are shown graphically as functions of the magnitude and direction of the geomagnetic field strength vector.

  9. An inverse problem for a mathematical model of aquaponic agriculture

    NASA Astrophysics Data System (ADS)

    Bobak, Carly; Kunze, Herb

    2017-01-01

    Aquaponic agriculture is a sustainable ecosystem that relies on a symbiotic relationship between fish and macrophytes. While the practice has been growing in popularity, relatively little mathematical models exist which aim to study the system processes. In this paper, we present a system of ODEs which aims to mathematically model the population and concetrations dynamics present in an aquaponic environment. Values of the parameters in the system are estimated from the literature so that simulated results can be presented to illustrate the nature of the solutions to the system. As well, a brief sensitivity analysis is performed in order to identify redundant parameters and highlight those which may need more reliable estimates. Specifically, an inverse problem with manufactured data for fish and plants is presented to demonstrate the ability of the collage theorem to recover parameter estimates.

  10. Decision science and cervical cancer.

    PubMed

    Cantor, Scott B; Fahs, Marianne C; Mandelblatt, Jeanne S; Myers, Evan R; Sanders, Gillian D

    2003-11-01

    Mathematical modeling is an effective tool for guiding cervical cancer screening, diagnosis, and treatment decisions for patients and policymakers. This article describes the use of mathematical modeling as outlined in five presentations from the Decision Science and Cervical Cancer session of the Second International Conference on Cervical Cancer held at The University of Texas M. D. Anderson Cancer Center, April 11-14, 2002. The authors provide an overview of mathematical modeling, especially decision analysis and cost-effectiveness analysis, and examples of how it can be used for clinical decision making regarding the prevention, diagnosis, and treatment of cervical cancer. Included are applications as well as theory regarding decision science and cervical cancer. Mathematical modeling can answer such questions as the optimal frequency for screening, the optimal age to stop screening, and the optimal way to diagnose cervical cancer. Results from one mathematical model demonstrated that a vaccine against high-risk strains of human papillomavirus was a cost-effective use of resources, and discussion of another model demonstrated the importance of collecting direct non-health care costs and time costs for cost-effectiveness analysis. Research presented indicated that care must be taken when applying the results of population-wide, cost-effectiveness analyses to reduce health disparities. Mathematical modeling can encompass a variety of theoretical and applied issues regarding decision science and cervical cancer. The ultimate objective of using decision-analytic and cost-effectiveness models is to identify ways to improve women's health at an economically reasonable cost. Copyright 2003 American Cancer Society.

  11. Mathematical model of polyethylene pipe bending stress state

    NASA Astrophysics Data System (ADS)

    Serebrennikov, Anatoly; Serebrennikov, Daniil

    2018-03-01

    Introduction of new machines and new technologies of polyethylene pipeline installation is usually based on the polyethylene pipe flexibility. It is necessary that existing bending stresses do not lead to an irreversible polyethylene pipe deformation and to violation of its strength characteristics. Derivation of the mathematical model which allows calculating analytically the bending stress level of polyethylene pipes with consideration of nonlinear characteristics is presented below. All analytical calculations made with the mathematical model are experimentally proved and confirmed.

  12. Mathematical modelling of an electromagnetics automobile suspension

    NASA Astrophysics Data System (ADS)

    Amin, Ahmad Zaki Mohamad; Ahmad, Shamsuddin; Hoe, Yeak Su

    2017-04-01

    The mathematical modelling of the electromagnetic automobile suspension (EAS) is presented. The solution of the model is found using Runge-Kutta Method via MAPLE. The graphs of the vertical displacement, different vertical displacement and road profiles and acceleration of car body against time are investigated and validated using certain criteria.

  13. Improvement of mathematical models for simulation of vehicle handling : volume 7 : technical manual for the general simulation

    DOT National Transportation Integrated Search

    1980-03-01

    This volume is the technical manual for the general simulation. Mathematical modelling of the vehicle and of the human driver is presented in detail, as are differences between the APL simulation and the current one. Information on model validation a...

  14. Mathematical formulation of the Applications Technology Satellite-F (ATS-F) orbital maneuver control program (CNTRLF)

    NASA Technical Reports Server (NTRS)

    Goorevich, C. E.

    1975-01-01

    The mathematical formulation is presented of CNTRLF, the maneuver control program for the Applications Technology Satellite-F (ATS-F). The purpose is to specify the mathematical models that are included in the design of CNTRLF.

  15. Maths Circus: Boomerangs

    ERIC Educational Resources Information Center

    Humble, Steve; Briarley, Derel; Mappouridou, Christina; Duncan, Gavin; Turner, David; Handley, Jodi

    2006-01-01

    This paper presents an example of boomerang motion in mathematical terms available to students studying A-level mathematics. The theory developed in the paper postulates possible mathematical models that are verified by experimental results. The paper centres on the three-wing boomerang invented by Professor Yutaka Nishiyama.

  16. An Examination of Multiple Intelligence Domains and Learning Styles of Pre-Service Mathematics Teachers: Their Reflections on Mathematics Education

    ERIC Educational Resources Information Center

    Ozgen, Kemal; Tataroglu, Berna; Alkan, Huseyin

    2011-01-01

    The present study aims to identify pre-service mathematics teachers' multiple intelligence domains and learning style profiles, and to establish relationships between them. Employing the survey model, the study was conducted with the participation of 243 pre-service mathematics teachers. The study used the "multiple intelligence domains…

  17. Mathematical models for optimization of the centrifugal stage of a refrigerating compressor

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nuzhdin, A.S.

    1987-09-01

    The authors describe a general approach to the creating of mathematical models of energy and head losses in the flow part of the centrifugal compressor. The mathematical model of the pressure head and efficiency of a two-section stage proposed in this paper is meant for determining its characteristics for the assigned geometric dimensions and for optimizing by variance calculations. Characteristic points on the plot of velocity distribution over the margin of the vanes of the impeller and the diffuser of the centrifugal stage with a combined diffuser are presented. To assess the reliability of the mathematical model the authors comparedmore » some calculated data with the experimental ones.« less

  18. Mathematical Modelling and the Learning Trajectory: Tools to Support the Teaching of Linear Algebra

    ERIC Educational Resources Information Center

    Cárcamo Bahamonde, Andrea Dorila; Fortuny Aymemí, Josep Maria; Gómez i Urgellés, Joan Vicenç

    2017-01-01

    In this article we present a didactic proposal for teaching linear algebra based on two compatible theoretical models: emergent models and mathematical modelling. This proposal begins with a problematic situation related to the creation and use of secure passwords, which leads students toward the construction of the concepts of spanning set and…

  19. Empirical Evaluation of a Mathematical Model of Ethnolinguistic Vitality: The Case of Voro

    ERIC Educational Resources Information Center

    Ehala, Martin; Niglas, Katrin

    2007-01-01

    The paper presents the results of an empirical evaluation of a mathematical model of ethnolinguistic vitality. The model adds several new factors to the set used in previous models of ethnolinguistic vitality and operationalises it in a manner that would make it easier to compare the vitality of different groups. According to the model, the…

  20. Modeling of processing technologies in food industry

    NASA Astrophysics Data System (ADS)

    Korotkov, V. G.; Sagitov, R. F.; Popov, V. P.; Bachirov, V. D.; Akhmadieva, Z. R.; TSirkaeva, E. A.

    2018-03-01

    Currently, the society is facing an urgent need to solve the problems of nutrition (products with increased nutrition value) and to develop energy-saving technologies for food products. A mathematical modeling of heat and mass transfer of polymer materials in the extruder is rather successful these days. Mathematical description of movement and heat exchange during extrusion of gluten-protein-starch-containing material similar to pasta dough in its structure, were taken as a framework for the mathematical model presented in this paper.

  1. Phase demodulation method from a single fringe pattern based on correlation with a polynomial form.

    PubMed

    Robin, Eric; Valle, Valéry; Brémand, Fabrice

    2005-12-01

    The method presented extracts the demodulated phase from only one fringe pattern. Locally, this method approaches the fringe pattern morphology with the help of a mathematical model. The degree of similarity between the mathematical model and the real fringe is estimated by minimizing a correlation function. To use an optimization process, we have chosen a polynomial form such as a mathematical model. However, the use of a polynomial form induces an identification procedure with the purpose of retrieving the demodulated phase. This method, polynomial modulated phase correlation, is tested on several examples. Its performance, in terms of speed and precision, is presented on very noised fringe patterns.

  2. Subject design and factors affecting achievement in mathematics for biomedical science

    NASA Astrophysics Data System (ADS)

    Carnie, Steven; Morphett, Anthony

    2017-01-01

    Reports such as Bio2010 emphasize the importance of integrating mathematical modelling skills into undergraduate biology and life science programmes, to ensure students have the skills and knowledge needed for biological research in the twenty-first century. One way to do this is by developing a dedicated mathematics subject to teach modelling and mathematical concepts in biological contexts. We describe such a subject at a research-intensive Australian university, and discuss the considerations informing its design. We also present an investigation into the effect of mathematical and biological background, prior mathematical achievement, and gender, on student achievement in the subject. The investigation shows that several factors known to predict performance in standard calculus subjects apply also to specialized discipline-specific mathematics subjects, and give some insight into the relative importance of mathematical versus biological background for a biology-focused mathematics subject.

  3. State of charge modeling of lithium-ion batteries using dual exponential functions

    NASA Astrophysics Data System (ADS)

    Kuo, Ting-Jung; Lee, Kung-Yen; Huang, Chien-Kang; Chen, Jau-Horng; Chiu, Wei-Li; Huang, Chih-Fang; Wu, Shuen-De

    2016-05-01

    A mathematical model is developed by fitting the discharging curve of LiFePO4 batteries and used to investigate the relationship between the state of charge and the closed-circuit voltage. The proposed mathematical model consists of dual exponential terms and a constant term which can fit the characteristics of dual equivalent RC circuits closely, representing a LiFePO4 battery. One exponential term presents the stable discharging behavior and the other one presents the unstable discharging behavior and the constant term presents the cut-off voltage.

  4. Mathematical Learning Models that Depend on Prior Knowledge and Instructional Strategies

    ERIC Educational Resources Information Center

    Pritchard, David E.; Lee, Young-Jin; Bao, Lei

    2008-01-01

    We present mathematical learning models--predictions of student's knowledge vs amount of instruction--that are based on assumptions motivated by various theories of learning: tabula rasa, constructivist, and tutoring. These models predict the improvement (on the post-test) as a function of the pretest score due to intervening instruction and also…

  5. MATHEMATICAL MODEL FOR AEROSOL DEPOSITION IN THE RESPIRATORY TRACT OF THE GUINEA PIG

    EPA Science Inventory

    Laboratory animals are used as surrogates in inhalation exposure studies for: 1) risk assessments of air pollutants; and, (2) evaluations of pharmacologic drugs. erein, a mathematical model is presented which identifies factors affecting the regional distribution of inhaled aeros...

  6. A theory of drug tolerance and dependence II: the mathematical model.

    PubMed

    Peper, Abraham

    2004-08-21

    The preceding paper presented a model of drug tolerance and dependence. The model assumes the development of tolerance to a repeatedly administered drug to be the result of a regulated adaptive process. The oral detection and analysis of exogenous substances is proposed to be the primary stimulus for the mechanism of drug tolerance. Anticipation and environmental cues are in the model considered secondary stimuli, becoming primary in dependence and addiction or when the drug administration bypasses the natural-oral-route, as is the case when drugs are administered intravenously. The model considers adaptation to the effect of a drug and adaptation to the interval between drug taking autonomous tolerance processes. Simulations with the mathematical model demonstrate the model's behaviour to be consistent with important characteristics of the development of tolerance to repeatedly administered drugs: the gradual decrease in drug effect when tolerance develops, the high sensitivity to small changes in drug dose, the rebound phenomenon and the large reactions following withdrawal in dependence. The present paper discusses the mathematical model in terms of its design. The model is a nonlinear, learning feedback system, fully satisfying control theoretical principles. It accepts any form of the stimulus-the drug intake-and describes how the physiological processes involved affect the distribution of the drug through the body and the stability of the regulation loop. The mathematical model verifies the proposed theory and provides a basis for the implementation of mathematical models of specific physiological processes.

  7. The Mathematics of Medical Imaging in the Classroom

    ERIC Educational Resources Information Center

    Funkhouser, Charles P.; Jafari, Farhad; Eubank, William B.

    2002-01-01

    The article presents an integrated exposition of aspects of secondary school mathematics and a medical science specialty together with related classroom activities. Clinical medical practice and theoretical and empirical literature in mathematics education and radiology were reviewed to develop and pilot model integrative classroom topics and…

  8. On MTE-Model of Mathematics Teaching: Studying the Problems Related to a Plane Division Using the MTE-Model

    ERIC Educational Resources Information Center

    Bodroza-Pantic, O.; Matic-Kekic, Snezana; Jakovljev, Bogdanka; Markovic, Doko

    2008-01-01

    In this paper the didactically-methodological procedure named the MTE-model of mathematics teaching (Motivation test-Teaching-Examination test) is suggested and recommended when the teacher has subsequent lessons. This model is presented in detail through the processing of a nonstandard theme--the theme of decomposition of planes. Its efficiency…

  9. A Novel Approach to Develop the Lower Order Model of Multi-Input Multi-Output System

    NASA Astrophysics Data System (ADS)

    Rajalakshmy, P.; Dharmalingam, S.; Jayakumar, J.

    2017-10-01

    A mathematical model is a virtual entity that uses mathematical language to describe the behavior of a system. Mathematical models are used particularly in the natural sciences and engineering disciplines like physics, biology, and electrical engineering as well as in the social sciences like economics, sociology and political science. Physicists, Engineers, Computer scientists, and Economists use mathematical models most extensively. With the advent of high performance processors and advanced mathematical computations, it is possible to develop high performing simulators for complicated Multi Input Multi Ouptut (MIMO) systems like Quadruple tank systems, Aircrafts, Boilers etc. This paper presents the development of the mathematical model of a 500 MW utility boiler which is a highly complex system. A synergistic combination of operational experience, system identification and lower order modeling philosophy has been effectively used to develop a simplified but accurate model of a circulation system of a utility boiler which is a MIMO system. The results obtained are found to be in good agreement with the physics of the process and with the results obtained through design procedure. The model obtained can be directly used for control system studies and to realize hardware simulators for boiler testing and operator training.

  10. Epidemics of panic during a bioterrorist attack--a mathematical model.

    PubMed

    Radosavljevic, Vladan; Radunovic, Desanka; Belojevic, Goran

    2009-09-01

    A bioterrorist attacks usually cause epidemics of panic in a targeted population. We have presented epidemiologic aspect of this phenomenon as a three-component model--host, information on an attack and social network. We have proposed a mathematical model of panic and counter-measures as the function of time in a population exposed to a bioterrorist attack. The model comprises ordinary differential equations and graphically presented combinations of the equations parameters. Clinically, we have presented a model through a sequence of psychic conditions and disorders initiated by an act of bioterrorism. This model might be helpful for an attacked community to timely and properly apply counter-measures and to minimize human mental suffering during a bioterrorist attack.

  11. Modeling in the quality by design environment: Regulatory requirements and recommendations for design space and control strategy appointment.

    PubMed

    Djuris, Jelena; Djuric, Zorica

    2017-11-30

    Mathematical models can be used as an integral part of the quality by design (QbD) concept throughout the product lifecycle for variety of purposes, including appointment of the design space and control strategy, continual improvement and risk assessment. Examples of different mathematical modeling techniques (mechanistic, empirical and hybrid) in the pharmaceutical development and process monitoring or control are provided in the presented review. In the QbD context, mathematical models are predominantly used to support design space and/or control strategies. Considering their impact to the final product quality, models can be divided into the following categories: high, medium and low impact models. Although there are regulatory guidelines on the topic of modeling applications, review of QbD-based submission containing modeling elements revealed concerns regarding the scale-dependency of design spaces and verification of models predictions at commercial scale of manufacturing, especially regarding real-time release (RTR) models. Authors provide critical overview on the good modeling practices and introduce concepts of multiple-unit, adaptive and dynamic design space, multivariate specifications and methods for process uncertainty analysis. RTR specification with mathematical model and different approaches to multivariate statistical process control supporting process analytical technologies are also presented. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. A Holistic Model to Infer Mathematics Performance: The Interrelated Impact of Student, Family and School Context Variables

    ERIC Educational Resources Information Center

    Zhao, Ningning; Valcke, Martin; Desoete, Annemie; Zhu, Chang; Sang, Guoyuan; Verhaeghe, JeanPierre

    2014-01-01

    The present study aims at exploring predictors influencing mathematics performance. In particular, the study focuses on internal students' characteristics (gender, age, metacognitive experience, mathematics self-efficacy) and external contextual factors (GDP of school location, parents' educational level, teachers' educational level, and teacher…

  13. Aspects of job scheduling

    NASA Technical Reports Server (NTRS)

    Phillips, K.

    1976-01-01

    A mathematical model for job scheduling in a specified context is presented. The model uses both linear programming and combinatorial methods. While designed with a view toward optimization of scheduling of facility and plant operations at the Deep Space Communications Complex, the context is sufficiently general to be widely applicable. The general scheduling problem including options for scheduling objectives is discussed and fundamental parameters identified. Mathematical algorithms for partitioning problems germane to scheduling are presented.

  14. Mathematical estimation of the level of microbial contamination on spacecraft surfaces by volumetric air sampling

    NASA Technical Reports Server (NTRS)

    Oxborrow, G. S.; Roark, A. L.; Fields, N. D.; Puleo, J. R.

    1974-01-01

    Microbiological sampling methods presently used for enumeration of microorganisms on spacecraft surfaces require contact with easily damaged components. Estimation of viable particles on surfaces using air sampling methods in conjunction with a mathematical model would be desirable. Parameters necessary for the mathematical model are the effect of angled surfaces on viable particle collection and the number of viable cells per viable particle. Deposition of viable particles on angled surfaces closely followed a cosine function, and the number of viable cells per viable particle was consistent with a Poisson distribution. Other parameters considered by the mathematical model included deposition rate and fractional removal per unit time. A close nonlinear correlation between volumetric air sampling and airborne fallout on surfaces was established with all fallout data points falling within the 95% confidence limits as determined by the mathematical model.

  15. School Mathematics Study Group, Unit Number Two. Chapter 3 - Informal Algorithms and Flow Charts. Chapter 4 - Applications and Mathematics Models.

    ERIC Educational Resources Information Center

    Stanford Univ., CA. School Mathematics Study Group.

    This is the second unit of a 15-unit School Mathematics Study Group (SMSG) mathematics text for high school students. Topics presented in the first chapter (Informal Algorithms and Flow Charts) include: changing a flat tire; algorithms, flow charts, and computers; assignment and variables; input and output; using a variable as a counter; decisions…

  16. Mathematical, Constitutive and Numerical Modelling of Catastrophic Landslides and Related Phenomena

    NASA Astrophysics Data System (ADS)

    Pastor, M.; Fernández Merodo, J. A.; Herreros, M. I.; Mira, P.; González, E.; Haddad, B.; Quecedo, M.; Tonni, L.; Drempetic, V.

    2008-02-01

    Mathematical and numerical models are a fundamental tool for predicting the behaviour of geostructures and their interaction with the environment. The term “mathematical model” refers to a mathematical description of the more relevant physical phenomena which take place in the problem being analyzed. It is indeed a wide area including models ranging from the very simple ones for which analytical solutions can be obtained to those more complicated requiring the use of numerical approximations such as the finite element method. During the last decades, mathematical, constitutive and numerical models have been very much improved and today their use is widespread both in industry and in research. One special case is that of fast catastrophic landslides, for which simplified methods are not able to provide accurate solutions in many occasions. Moreover, many finite element codes cannot be applied for propagation of the mobilized mass. The purpose of this work is to present an overview of the different alternative mathematical and numerical models which can be applied to both the initiation and propagation mechanisms of fast catastrophic landslides and other related problems such as waves caused by landslides.

  17. Analysis of shell-type structures subjected to time-dependent mechanical and thermal loading

    NASA Technical Reports Server (NTRS)

    Simitses, George J.

    1990-01-01

    The development of a general mathematical model and solution methodologies for analyzing structural response of thin, metallic shell-like structures under dynamic and/or static thermomechanical loads is examined. In the mathematical model, geometric as well as material-type of nonlinearities are considered. Traditional as well as novel approaches are reported and detailed applications are presented in the appendices. The emphasis for the mathematical model, the related solution schemes, and the applications, is on thermal viscoelastic and viscoplastic phenomena, which can predict creep and ratchetting.

  18. Analysis of shell-type structures subjected to time-dependent mechanical and thermal loading

    NASA Technical Reports Server (NTRS)

    Simitses, G. J.

    1991-01-01

    This report deals with the development of a general mathematical model and solution methodology for analyzing the structural response of thin, metallic shell-like structures under dynamic and/or static thermomechanical loads. In the mathematical model, geometric as well as the material-type of nonlinearities are considered. Traditional as well as novel approaches are reported and detailed applications are presented in the appendices. The emphasis for the mathematical model, the related solution schemes, and the applications, is on thermal viscoelastic and viscoplastic phenomena, which can predict creep and ratchetting.

  19. Modelling in Action. Examining How Students Approach Modelling Real Life Situations. Three Case Studies. Model of the Movement of an Elevator

    ERIC Educational Resources Information Center

    Rivas, Eugenia Marmolejo

    2015-01-01

    By means of three case studies, we will present two mathematical modelling activities that are suitable for students enrolled in senior high school and the first year of mathematics at university level. The activities have been designed to enrich the learning process and promote the formation of vital modelling skills. In case studies one and two,…

  20. Mathematical model and stability analysis of fluttering and autorotation of an articulated plate into a flow

    NASA Astrophysics Data System (ADS)

    Rostami, Ali Bakhshandeh; Fernandes, Antonio Carlos

    2018-03-01

    This paper is dedicated to develop a mathematical model that can simulate nonlinear phenomena of a hinged plate which places into the fluid flow (1 DOF). These phenomena are fluttering (oscillation motion), autorotation (continuous rotation) and chaotic motion (combination of fluttering and autorotation). Two mathematical models are developed for 1 DOF problem using two eminent mathematical models which had been proposed for falling plates (3 DOF). The procedures of developing these models are elaborated and then these results are compared to experimental data. The best model in the simulation of the phenomena is chosen for stability and bifurcation analysis. Based on these analyses, this model shows a transcritical bifurcation and as a result, the stability diagram and threshold are presented. Moreover, an analytical expression is given for finding the boundary of bifurcation from the fluttering to the autorotation.

  1. Predictors of Visualization: A Structural Equation Model.

    ERIC Educational Resources Information Center

    Robichaux, Rebecca R.; Guarino, A. J.

    This study tested a causal model of the development of spatial visualization based on a synthesis of past and present research. During the summer and fall of 1999, 117 third- and fourth-year undergraduates majoring in architecture, mathematics, mathematics education, and mechanical engineering completed a spatial visualization test and a…

  2. Forest Fires, Oil Spills, and Fractal Geometry: An Investigation in Two Parts. Part 2: Using Fractal Complexity to Analyze Mathematical Models.

    ERIC Educational Resources Information Center

    Biehl, L. Charles

    1999-01-01

    Presents an activity that utilizes the mathematical models of forest fires and oil spills that were generated (in the first part of this activity, published in the November 1998 issue) by students using probability and cellular automata. (ASK)

  3. Mathematical modeling of inhalation exposure

    NASA Technical Reports Server (NTRS)

    Fiserova-Bergerova, V.

    1976-01-01

    The paper presents a mathematical model of inhalation exposure in which uptake, distribution and excretion are described by exponential functions, while rate constants are determined by tissue volumes, blood perfusion and by the solubility of vapors (partition coefficients). In the model, tissues are grouped into four pharmokinetic compartments. The model is used to study continuous and interrupted chronic exposures and is applied to the inhalation of Forane and methylene chloride.

  4. Evaluation of Limb Load Asymmetry Using Two New Mathematical Models

    PubMed Central

    Kumar, Senthil NS; Omar, Baharudin; Joseph, Leonard H.; Htwe, Ohnmar; Jagannathan, K.; Hamdan, Nor M Y; Rajalakshmi, D.

    2015-01-01

    Quantitative measurement of limb loading is important in orthopedic and neurological rehabilitation. In current practice, mathematical models such as Symmetry index (SI), Symmetry ratio (SR), and Symmetry angle (SA) are used to quantify limb loading asymmetry. Literatures have identified certain limitations with the above mathematical models. Hence this study presents two new mathematical models Modified symmetry index (MSI) and Limb loading error (LLE) that would address these limitations. Furthermore, the current mathematical models were compared against the new model with the goal of achieving a better model. This study uses hypothetical data to simulate an algorithmic preliminary computational measure to perform with all numerical possibilities of even and uneven limb loading that can occur in human legs. Descriptive statistics are used to interpret the limb loading patterns: symmetry, asymmetry and maximum asymmetry. The five mathematical models were similar in analyzing symmetry between limbs. However, for asymmetry and maximum asymmetry data, the SA and SR values do not give any meaningful interpretation, and SI gives an inflated value. The MSI and LLE are direct, easy to interpret and identify the loading patterns with the side of asymmetry. The new models are notable as they quantify the amount and side of asymmetry under different loading patterns. PMID:25716372

  5. Mathematical modeling of the aerodynamics of high-angle-of-attack maneuvers

    NASA Technical Reports Server (NTRS)

    Schiff, L. B.; Tobak, M.; Malcolm, G. N.

    1980-01-01

    This paper is a review of the current state of aerodynamic mathematical modeling for aircraft motions at high angles of attack. The mathematical model serves to define a set of characteristic motions from whose known aerodynamic responses the aerodynamic response to an arbitrary high angle-of-attack flight maneuver can be predicted. Means are explored of obtaining stability parameter information in terms of the characteristic motions, whether by wind-tunnel experiments, computational methods, or by parameter-identification methods applied to flight-test data. A rationale is presented for selecting and verifying the aerodynamic mathematical model at the lowest necessary level of complexity. Experimental results describing the wing-rock phenomenon are shown to be accommodated within the most recent mathematical model by admitting the existence of aerodynamic hysteresis in the steady-state variation of the rolling moment with roll angle. Interpretation of the experimental results in terms of bifurcation theory reveals the general conditions under which aerodynamic hysteresis must exist.

  6. UH-60A Black Hawk engineering simulation program. Volume 1: Mathematical model

    NASA Technical Reports Server (NTRS)

    Howlett, J. J.

    1981-01-01

    A nonlinear mathematical model of the UR-60A Black Hawk helicopter was developed. This mathematical model, which was based on the Sikorsky General Helicopter (Gen Hel) Flight Dynamics Simulation, provides NASA with an engineering simulation for performance and handling qualities evaluations. This mathematical model is total systems definition of the Black Hawk helicopter represented at a uniform level of sophistication considered necessary for handling qualities evaluations. The model is a total force, large angle representation in six rigid body degrees of freedom. Rotor blade flapping, lagging, and hub rotational degrees of freedom are also represented. In addition to the basic helicopter modules, supportive modules were defined for the landing interface, power unit, ground effects, and gust penetration. Information defining the cockpit environment relevant to pilot in the loop simulation is presented.

  7. Development of Mathematical Literacy: Results of an Empirical Study

    ERIC Educational Resources Information Center

    Kaiser, Gabriele; Willander, Torben

    2005-01-01

    In the paper the results of an empirical study, which has evaluated the development of mathematical literacy in an innovative teaching programme, are presented. The theoretical approach of mathematical literacy relies strongly on applications and modelling and the study follows the approach of R. Bybee, who develops a theoretical concept of…

  8. Method and system to perform energy-extraction based active noise control

    NASA Technical Reports Server (NTRS)

    Kelkar, Atul (Inventor); Joshi, Suresh M. (Inventor)

    2009-01-01

    A method to provide active noise control to reduce noise and vibration in reverberant acoustic enclosures such as aircraft, vehicles, appliances, instruments, industrial equipment and the like is presented. A continuous-time multi-input multi-output (MIMO) state space mathematical model of the plant is obtained via analytical modeling and system identification. Compensation is designed to render the mathematical model passive in the sense of mathematical system theory. The compensated system is checked to ensure robustness of the passive property of the plant. The check ensures that the passivity is preserved if the mathematical model parameters are perturbed from nominal values. A passivity-based controller is designed and verified using numerical simulations and then tested. The controller is designed so that the resulting closed-loop response shows the desired noise reduction.

  9. How to Build a Course in Mathematical–Biological Modeling: Content and Processes for Knowledge and Skill

    PubMed Central

    2010-01-01

    Biological problems in the twenty-first century are complex and require mathematical insight, often resulting in mathematical models of biological systems. Building mathematical–biological models requires cooperation among biologists and mathematicians, and mastery of building models. A new course in mathematical modeling presented the opportunity to build both content and process learning of mathematical models, the modeling process, and the cooperative process. There was little guidance from the literature on how to build such a course. Here, I describe the iterative process of developing such a course, beginning with objectives and choosing content and process competencies to fulfill the objectives. I include some inductive heuristics for instructors seeking guidance in planning and developing their own courses, and I illustrate with a description of one instructional model cycle. Students completing this class reported gains in learning of modeling content, the modeling process, and cooperative skills. Student content and process mastery increased, as assessed on several objective-driven metrics in many types of assessments. PMID:20810966

  10. Graph Theory and the High School Student.

    ERIC Educational Resources Information Center

    Chartrand, Gary; Wall, Curtiss E.

    1980-01-01

    Graph theory is presented as a tool to instruct high school mathematics students. A variety of real world problems can be modeled which help students recognize the importance and difficulty of applying mathematics. (MP)

  11. Mathematical model for thermal and entropy analysis of thermal solar collectors by using Maxwell nanofluids with slip conditions, thermal radiation and variable thermal conductivity

    NASA Astrophysics Data System (ADS)

    Aziz, Asim; Jamshed, Wasim; Aziz, Taha

    2018-04-01

    In the present research a simplified mathematical model for the solar thermal collectors is considered in the form of non-uniform unsteady stretching surface. The non-Newtonian Maxwell nanofluid model is utilized for the working fluid along with slip and convective boundary conditions and comprehensive analysis of entropy generation in the system is also observed. The effect of thermal radiation and variable thermal conductivity are also included in the present model. The mathematical formulation is carried out through a boundary layer approach and the numerical computations are carried out for Cu-water and TiO2-water nanofluids. Results are presented for the velocity, temperature and entropy generation profiles, skin friction coefficient and Nusselt number. The discussion is concluded on the effect of various governing parameters on the motion, temperature variation, entropy generation, velocity gradient and the rate of heat transfer at the boundary.

  12. Asymmetrical booster ascent guidance and control system design study. Volume 2: SSFS math models - Ascent. [space shuttle development

    NASA Technical Reports Server (NTRS)

    Williams, F. E.; Lemon, R. S.

    1974-01-01

    The engineering equations and mathematical models developed for use in the space shuttle functional simulator (SSFS) are presented, and include extensive revisions and additions to earlier documentation. Definitions of coordinate systems used by the SSFS models and coordinate tranformations are given, along with documentation of the flexible body mathematical models. The models were incorporated in the SSFS and are in the checkout stage.

  13. Mathematical model for the dc-ac inverter for the Space Shuttle

    NASA Technical Reports Server (NTRS)

    Berry, Frederick C.

    1987-01-01

    The reader is informed of what was done for the mathematical modeling of the dc-ac inverter for the Space Shuttle. The mathematical modeling of the dc-ac inverter is an essential element in the modeling of the electrical power distribution system of the Space Shuttle. The electrical power distribution system which is present on the Space Shuttle is made up to 3 strings each having a fuel cell which provides dc to those systems which require dc, and the inverters which convert the dc to ac for those elements which require ac. The inverters are units which are 2 wire structures for the main dc inputs and 2 wire structures for the ac output. When 3 are connected together a 4 wire wye connection results on the ac side. The method of modeling is performed by using a Least Squares curve fitting method. A computer program is presented for implementation of the model along with graphs and tables to demonstrate the accuracy of the model.

  14. A Mathematical Model of the Great Solar Eclipse of 1991.

    ERIC Educational Resources Information Center

    Lamb, John Jr.

    1991-01-01

    An activity that shows how mathematics can be used to model events in the real world is described. A way to calculate the area of the sun covered by the moon during a partial eclipse is presented. A computer program that will determine the coverage percentage is also included. (KR)

  15. Designing Online Learning for Developing Pre-Service Teachers' Capabilities in Mathematical Modelling and Applications

    ERIC Educational Resources Information Center

    Geiger, Vince; Date-Huxtable, Liz; Ahlip, Rehez; Herberstein, Marie; Jones, D. Heath; May, E. Julian; Rylands, Leanne; Wright, Ian; Mulligan, Joanne

    2016-01-01

    The purpose of this paper is to describe the processes utilised to develop an online learning module within the Opening Real Science (ORS) project--"Modelling the present: Predicting the future." The module was realised through an interdisciplinary collaboration, among mathematicians, scientists and mathematics and science educators that…

  16. Mathematical Models in Educational Planning. Education and Development, Technical Reports.

    ERIC Educational Resources Information Center

    Organisation for Economic Cooperation and Development, Paris (France).

    This volume contains papers, presented at a 1966 OECD meeting, on the possibilities of applying a number of related techniques such as mathematical model building, simulation, and systematic control theory to the problems of educational planning. The authors and their papers are (1) Richard Stone, "A View of the Conference," (2) Hector…

  17. Longitudinal Evaluation of a Scale-Up Model for Teaching Mathematics with Trajectories and Technologies: Mechanisms of Persistence of Effects

    ERIC Educational Resources Information Center

    Clements, Douglas H.

    2011-01-01

    The author and her colleagues' TRIAD model (Sarama, Clements, Starkey, Klein, & Wakeley, 2008), including the "Building Blocks" curriculum, have significantly and substantially increased preschooler's mathematical competence, both in previous studies (Clements & Sarama, 2008, g = 1.07) and in their present, largest implementation…

  18. A Developmental Mapping Program Integrating Geography and Mathematics.

    ERIC Educational Resources Information Center

    Muir, Sharon Pray; Cheek, Helen Neely

    Presented and discussed is a model which can be used by educators who want to develop an interdisciplinary map skills program in geography and mathematics. The model assumes that most children in elementary schools perform cognitively at Piaget's concrete operational stage, that readiness for map skills can be assessed with Piagetian or…

  19. Computer modeling of heat pipe performance

    NASA Technical Reports Server (NTRS)

    Peterson, G. P.

    1983-01-01

    A parametric study of the defining equations which govern the steady state operational characteristics of the Grumman monogroove dual passage heat pipe is presented. These defining equations are combined to develop a mathematical model which describes and predicts the operational and performance capabilities of a specific heat pipe given the necessary physical characteristics and working fluid. Included is a brief review of the current literature, a discussion of the governing equations, and a description of both the mathematical and computer model. Final results of preliminary test runs of the model are presented and compared with experimental tests on actual prototypes.

  20. The ‘hit’ phenomenon: a mathematical model of human dynamics interactions as a stochastic process

    NASA Astrophysics Data System (ADS)

    Ishii, Akira; Arakaki, Hisashi; Matsuda, Naoya; Umemura, Sanae; Urushidani, Tamiko; Yamagata, Naoya; Yoshida, Narihiko

    2012-06-01

    A mathematical model for the ‘hit’ phenomenon in entertainment within a society is presented as a stochastic process of human dynamics interactions. The model uses only the advertisement budget time distribution as an input, and word-of-mouth (WOM), represented by posts on social network systems, is used as data to make a comparison with the calculated results. The unit of time is days. The WOM distribution in time is found to be very close to the revenue distribution in time. Calculations for the Japanese motion picture market based on the mathematical model agree well with the actual revenue distribution in time.

  1. Redundancy management of electrohydraulic servoactuators by mathematical model referencing

    NASA Technical Reports Server (NTRS)

    Campbell, R. A.

    1971-01-01

    A description of a mathematical model reference system is presented which provides redundancy management for an electrohydraulic servoactuator. The mathematical model includes a compensation network that calculates reference parameter perturbations induced by external disturbance forces. This is accomplished by using the measured pressure differential data taken from the physical system. This technique was experimentally verified by tests performed using the H-1 engine thrust vector control system for Saturn IB. The results of these tests are included in this report. It was concluded that this technique improves the tracking accuracy of the model reference system to the extent that redundancy management of electrohydraulic servosystems may be performed using this method.

  2. Mathematical Metaphors: Problem Reformulation and Analysis Strategies

    NASA Technical Reports Server (NTRS)

    Thompson, David E.

    2005-01-01

    This paper addresses the critical need for the development of intelligent or assisting software tools for the scientist who is working in the initial problem formulation and mathematical model representation stage of research. In particular, examples of that representation in fluid dynamics and instability theory are discussed. The creation of a mathematical model that is ready for application of certain solution strategies requires extensive symbolic manipulation of the original mathematical model. These manipulations can be as simple as term reordering or as complicated as discovery of various symmetry groups embodied in the equations, whereby Backlund-type transformations create new determining equations and integrability conditions or create differential Grobner bases that are then solved in place of the original nonlinear PDEs. Several examples are presented of the kinds of problem formulations and transforms that can be frequently encountered in model representation for fluids problems. The capability of intelligently automating these types of transforms, available prior to actual mathematical solution, is advocated. Physical meaning and assumption-understanding can then be propagated through the mathematical transformations, allowing for explicit strategy development.

  3. A theory of drug tolerance and dependence I: a conceptual analysis.

    PubMed

    Peper, Abraham

    2004-08-21

    A mathematical model of drug tolerance and its underlying theory is presented. The model extends a first approach, published previously. The model is essentially more complex than the generally used model of homeostasis, which is demonstrated to fail in describing tolerance development to repeated drug administrations. The model assumes the development of tolerance to a repeatedly administered drug to be the result of a regulated adaptive process. The oral detection and analysis of exogenous substances is proposed to be the primary stimulus for the mechanism of drug tolerance. Anticipation and environmental cues are in the model considered secondary stimuli, becoming primary only in dependence and addiction or when the drug administration bypasses the natural-oral-route, as is the case when drugs are administered intravenously. The model considers adaptation to the effect of a drug and adaptation to the interval between drug taking autonomous tolerance processes. Simulations with the mathematical model demonstrate the model's behavior to be consistent with important characteristics of the development of tolerance to repeatedly administered drugs: the gradual decrease in drug effect when tolerance develops, the high sensitivity to small changes in drug dose, the rebound phenomenon and the large reactions following withdrawal in dependence. The mathematical model verifies the proposed theory and provides a basis for the implementation of mathematical models of specific physiological processes. In addition, it establishes a relation between the drug dose at any moment, and the resulting drug effect and relates the magnitude of the reactions following withdrawal to the rate of tolerance and other parameters involved in the tolerance process. The present paper analyses the concept behind the model. The next paper discusses the mathematical model.

  4. A tool for multi-scale modelling of the renal nephron

    PubMed Central

    Nickerson, David P.; Terkildsen, Jonna R.; Hamilton, Kirk L.; Hunter, Peter J.

    2011-01-01

    We present the development of a tool, which provides users with the ability to visualize and interact with a comprehensive description of a multi-scale model of the renal nephron. A one-dimensional anatomical model of the nephron has been created and is used for visualization and modelling of tubule transport in various nephron anatomical segments. Mathematical models of nephron segments are embedded in the one-dimensional model. At the cellular level, these segment models use models encoded in CellML to describe cellular and subcellular transport kinetics. A web-based presentation environment has been developed that allows the user to visualize and navigate through the multi-scale nephron model, including simulation results, at the different spatial scales encompassed by the model description. The Zinc extension to Firefox is used to provide an interactive three-dimensional view of the tubule model and the native Firefox rendering of scalable vector graphics is used to present schematic diagrams for cellular and subcellular scale models. The model viewer is embedded in a web page that dynamically presents content based on user input. For example, when viewing the whole nephron model, the user might be presented with information on the various embedded segment models as they select them in the three-dimensional model view. Alternatively, the user chooses to focus the model viewer on a cellular model located in a particular nephron segment in order to view the various membrane transport proteins. Selecting a specific protein may then present the user with a description of the mathematical model governing the behaviour of that protein—including the mathematical model itself and various simulation experiments used to validate the model against the literature. PMID:22670210

  5. Molecular modeling: An open invitation for applied mathematics

    NASA Astrophysics Data System (ADS)

    Mezey, Paul G.

    2013-10-01

    Molecular modeling methods provide a very wide range of challenges for innovative mathematical and computational techniques, where often high dimensionality, large sets of data, and complicated interrelations imply a multitude of iterative approximations. The physical and chemical basis of these methodologies involves quantum mechanics with several non-intuitive aspects, where classical interpretation and classical analogies are often misleading or outright wrong. Hence, instead of the everyday, common sense approaches which work so well in engineering, in molecular modeling one often needs to rely on rather abstract mathematical constraints and conditions, again emphasizing the high level of reliance on applied mathematics. Yet, the interdisciplinary aspects of the field of molecular modeling also generates some inertia and perhaps too conservative reliance on tried and tested methodologies, that is at least partially caused by the less than up-to-date involvement in the newest developments in applied mathematics. It is expected that as more applied mathematicians take up the challenge of employing the latest advances of their field in molecular modeling, important breakthroughs may follow. In this presentation some of the current challenges of molecular modeling are discussed.

  6. Antioxidant Capacity: Experimental Determination by EPR Spectroscopy and Mathematical Modeling.

    PubMed

    Polak, Justyna; Bartoszek, Mariola; Chorążewski, Mirosław

    2015-07-22

    A new method of determining antioxidant capacity based on a mathematical model is presented in this paper. The model was fitted to 1000 data points of electron paramagnetic resonance (EPR) spectroscopy measurements of various food product samples such as tea, wine, juice, and herbs with Trolox equivalent antioxidant capacity (TEAC) values from 20 to 2000 μmol TE/100 mL. The proposed mathematical equation allows for a determination of TEAC of food products based on a single EPR spectroscopy measurement. The model was tested on the basis of 80 EPR spectroscopy measurements of herbs, tea, coffee, and juice samples. The proposed model works for both strong and weak antioxidants (TEAC values from 21 to 2347 μmol TE/100 mL). The determination coefficient between TEAC values obtained experimentally and TEAC values calculated with proposed mathematical equation was found to be R(2) = 0.98. Therefore, the proposed new method of TEAC determination based on a mathematical model is a good alternative to the standard EPR method due to its being fast, accurate, inexpensive, and simple to perform.

  7. An Application of Mathematical Groups to Structures of Human Groups. Applications of Finite Mathematics to Anthropology and Sociology. Modules and Monographs in Undergraduate Mathematics and Its Applications Project. UMAP Unit 476.

    ERIC Educational Resources Information Center

    Carlson, Roger

    This module is designed for students with a high school algebra background. The goal is to present the elements of the group idea, primarily by way of a geometric model, and to see its application to the study of kinship relations within certain human groups. The material opens with a presentation of clans in a hypothetical society in an early…

  8. Computer-Based Mathematics Instructions for Engineering Students

    NASA Technical Reports Server (NTRS)

    Khan, Mustaq A.; Wall, Curtiss E.

    1996-01-01

    Almost every engineering course involves mathematics in one form or another. The analytical process of developing mathematical models is very important for engineering students. However, the computational process involved in the solution of some mathematical problems may be very tedious and time consuming. There is a significant amount of mathematical software such as Mathematica, Mathcad, and Maple designed to aid in the solution of these instructional problems. The use of these packages in classroom teaching can greatly enhance understanding, and save time. Integration of computer technology in mathematics classes, without de-emphasizing the traditional analytical aspects of teaching, has proven very successful and is becoming almost essential. Sample computer laboratory modules are developed for presentation in the classroom setting. This is accomplished through the use of overhead projectors linked to graphing calculators and computers. Model problems are carefully selected from different areas.

  9. Comparison among mathematical models of the photovoltaic cell for computer simulation purposes

    NASA Astrophysics Data System (ADS)

    Tofoli, Fernando Lessa; Pereira, Denis de Castro; Josias De Paula, Wesley; Moreira Vicente, Eduardo; Vicente, Paula dos Santos; Braga, Henrique Antonio Carvalho

    2017-07-01

    This paper presents a comparison among mathematical models used in the simulation of solar photovoltaic modules that can be easily integrated with power electronic converters. In order to perform the analysis, three models available in literature and also the physical model of the module in software PSIM® are used. Some results regarding the respective I × V and P × V curves are presented, while some advantages and eventual limitations are discussed. Besides, a DC-DC buck converter performs maximum power point tracking by using perturb and observe method, while the performance of each one of the aforementioned models is investigated.

  10. A mathematical model for late term cancer chemotherapy

    NASA Astrophysics Data System (ADS)

    Izard, Zac; Hirschbeck, Sarah; Volk, Christian; Shojania Feizabadi, Mitra

    2006-03-01

    A mathematical model for cancer treated with the ``on-off'' type where the drug is either active or inactive and when the chemotherapeutic treatment only affects the cycling cells is presented. This model is considered for late term chemotherapy when the total population of cells doesn't show a significant change. The size of the cycling cells as a function of time has been investigated.

  11. Mathematical modeling and simulation of the space shuttle imaging radar antennas

    NASA Technical Reports Server (NTRS)

    Campbell, R. W.; Melick, K. E.; Coffey, E. L., III

    1978-01-01

    Simulations of space shuttle synthetic aperture radar antennas under the influence of space environmental conditions were carried out at L, C, and X-band. Mathematical difficulties in modeling large, non-planar array antennas are discussed, and an approximate modeling technique is presented. Results for several antenna error conditions are illustrated in far-field profile patterns, earth surface footprint contours, and summary graphs.

  12. Using Mathematical Software to Introduce Fourier Transforms in Physical Chemistry to Develop Improved Understanding of Their Applications in Analytical Chemistry

    ERIC Educational Resources Information Center

    Miller, Tierney C.; Richardson, John N.; Kegerreis, Jeb S.

    2016-01-01

    This manuscript presents an exercise that utilizes mathematical software to explore Fourier transforms in the context of model quantum mechanical systems, thus providing a deeper mathematical understanding of relevant information often introduced and treated as a "black-box" in analytical chemistry courses. The exercise is given to…

  13. Improving Mathematics: An Examination of the Effects of Specific Cognitive Abilities on College-Age Students' Mathematics Achievement

    ERIC Educational Resources Information Center

    Taub, Gordon E.; Benson, Nicholas; Szente, Judit

    2014-01-01

    This study investigated the effects of general intelligence and seven specific cognitive abilities on college-age students' mathematics achievement. The present investigation went beyond previous research by employing structural equation modeling. It also represents the first study to examine the direct and indirect effects of general and specific…

  14. Complexity analysis and mathematical tools towards the modelling of living systems.

    PubMed

    Bellomo, N; Bianca, C; Delitala, M

    2009-09-01

    This paper is a review and critical analysis of the mathematical kinetic theory of active particles applied to the modelling of large living systems made up of interacting entities. The first part of the paper is focused on a general presentation of the mathematical tools of the kinetic theory of active particles. The second part provides a review of a variety of mathematical models in life sciences, namely complex social systems, opinion formation, evolution of epidemics with virus mutations, and vehicular traffic, crowds and swarms. All the applications are technically related to the mathematical structures reviewed in the first part of the paper. The overall contents are based on the concept that living systems, unlike the inert matter, have the ability to develop behaviour geared towards their survival, or simply to improve the quality of their life. In some cases, the behaviour evolves in time and generates destructive and/or proliferative events.

  15. Mathematical models for determining the protected spaces of the vertical lightning rod

    NASA Technical Reports Server (NTRS)

    Mladenovic, I.; Vorgucic, A.

    1991-01-01

    Two mathematical models are presented for determining the protected spaces of the vertical lightning-rod. In the first model there was applied the circular approximation. Through the introduction of the modified striking distance in the second improved approximation there was obtained a new model for the protected space of the lightning-rod. The models are of general type, foreseen for the three-dimensional space and they are simply applied on solving the practical problems.

  16. Application of mathematical modeling in sustained release delivery systems.

    PubMed

    Grassi, Mario; Grassi, Gabriele

    2014-08-01

    This review, presenting as starting point the concept of the mathematical modeling, is aimed at the physical and mathematical description of the most important mechanisms regulating drug delivery from matrix systems. The precise knowledge of the delivery mechanisms allows us to set up powerful mathematical models which, in turn, are essential for the design and optimization of appropriate drug delivery systems. The fundamental mechanisms for drug delivery from matrices are represented by drug diffusion, matrix swelling, matrix erosion, drug dissolution with possible recrystallization (e.g., as in the case of amorphous and nanocrystalline drugs), initial drug distribution inside the matrix, matrix geometry, matrix size distribution (in the case of spherical matrices of different diameter) and osmotic pressure. Depending on matrix characteristics, the above-reported variables may play a different role in drug delivery; thus the mathematical model needs to be built solely on the most relevant mechanisms of the particular matrix considered. Despite the somewhat diffident behavior of the industrial world, in the light of the most recent findings, we believe that mathematical modeling may have a tremendous potential impact in the pharmaceutical field. We do believe that mathematical modeling will be more and more important in the future especially in the light of the rapid advent of personalized medicine, a novel therapeutic approach intended to treat each single patient instead of the 'average' patient.

  17. The Modulus of Rupture from a Mathematical Point of View

    NASA Astrophysics Data System (ADS)

    Quintela, P.; Sánchez, M. T.

    2007-04-01

    The goal of this work is to present a complete mathematical study about the three-point bending experiments and the modulus of rupture of brittle materials. We will present the mathematical model associated to three-point bending experiments and we will use the asymptotic expansion method to obtain a new formula to calculate the modulus of rupture. We will compare the modulus of rupture of porcelain obtained with the previous formula with that obtained by using the classic theoretical formula. Finally, we will also present one and three-dimensional numerical simulations to compute the modulus of rupture.

  18. Attitude Determination Error Analysis System (ADEAS) mathematical specifications document

    NASA Technical Reports Server (NTRS)

    Nicholson, Mark; Markley, F.; Seidewitz, E.

    1988-01-01

    The mathematical specifications of Release 4.0 of the Attitude Determination Error Analysis System (ADEAS), which provides a general-purpose linear error analysis capability for various spacecraft attitude geometries and determination processes, are presented. The analytical basis of the system is presented. The analytical basis of the system is presented, and detailed equations are provided for both three-axis-stabilized and spin-stabilized attitude sensor models.

  19. Focusing on Interactions between Content and Cognition: A New Perspective on Gender Differences in Mathematical Sub-Competencies

    ERIC Educational Resources Information Center

    George, Ann Cathrice; Robitzsch, Alexander

    2018-01-01

    This article presents a new perspective on measuring gender differences in the large-scale assessment study Trends in International Science Study (TIMSS). The suggested empirical model is directly based on the theoretical competence model of the domain mathematics and thus includes the interaction between content and cognitive sub-competencies.…

  20. Biological system interactions.

    PubMed Central

    Adomian, G; Adomian, G E; Bellman, R E

    1984-01-01

    Mathematical modeling of cellular population growth, interconnected subsystems of the body, blood flow, and numerous other complex biological systems problems involves nonlinearities and generally randomness as well. Such problems have been dealt with by mathematical methods often changing the actual model to make it tractable. The method presented in this paper (and referenced works) allows much more physically realistic solutions. PMID:6585837

  1. Students' Big Three Personality Traits, Perceptions of Teacher Interpersonal Behavior, and Mathematics Achievement: An Application of the Model of Reciprocal Causation

    ERIC Educational Resources Information Center

    Charalampous, Kyriakos; Kokkinos, Constantinos M.

    2014-01-01

    The purpose of the present study was to investigate the application of the Model of Reciprocal Causation (MRC) in examining the relationship between student personality (personal factors), student-perceived teacher interpersonal behavior (environment), and Mathematics achievement (behavior), with the simultaneous investigation of mediating effects…

  2. Homework Works If Homework Quality Is High: Using Multilevel Modeling to Predict the Development of Achievement in Mathematics

    ERIC Educational Resources Information Center

    Dettmers, Swantje; Trautwein, Ulrich; Ludtke, Oliver; Kunter, Mareike; Baumert, Jurgen

    2010-01-01

    The present study examined the associations of 2 indicators of homework quality (homework selection and homework challenge) with homework motivation, homework behavior, and mathematics achievement. Multilevel modeling was used to analyze longitudinal data from a representative national sample of 3,483 students in Grades 9 and 10; homework effects…

  3. A mathematical model for predicting fire spread in wildland fuels

    Treesearch

    Richard C. Rothermel

    1972-01-01

    A mathematical fire model for predicting rate of spread and intensity that is applicable to a wide range of wildland fuels and environment is presented. Methods of incorporating mixtures of fuel sizes are introduced by weighting input parameters by surface area. The input parameters do not require a prior knowledge of the burning characteristics of the fuel.

  4. Improving science and mathematics education with computational modelling in interactive engagement environments

    NASA Astrophysics Data System (ADS)

    Neves, Rui Gomes; Teodoro, Vítor Duarte

    2012-09-01

    A teaching approach aiming at an epistemologically balanced integration of computational modelling in science and mathematics education is presented. The approach is based on interactive engagement learning activities built around computational modelling experiments that span the range of different kinds of modelling from explorative to expressive modelling. The activities are designed to make a progressive introduction to scientific computation without requiring prior development of a working knowledge of programming, generate and foster the resolution of cognitive conflicts in the understanding of scientific and mathematical concepts and promote performative competency in the manipulation of different and complementary representations of mathematical models. The activities are supported by interactive PDF documents which explain the fundamental concepts, methods and reasoning processes using text, images and embedded movies, and include free space for multimedia enriched student modelling reports and teacher feedback. To illustrate, an example from physics implemented in the Modellus environment and tested in undergraduate university general physics and biophysics courses is discussed.

  5. Development Of Maneuvering Autopilot For Flight Tests

    NASA Technical Reports Server (NTRS)

    Menon, P. K. A.; Walker, R. A.

    1992-01-01

    Report describes recent efforts to develop automatic control system operating under supervision of pilot and making airplane follow prescribed trajectories during flight tests. Report represents additional progress on this project. Gives background information on technology of control of test-flight trajectories; presents mathematical models of airframe, engine and command-augmentation system; focuses on mathematical modeling of maneuvers; addresses design of autopilots for maneuvers; discusses numerical simulation and evaluation of results of simulation of eight maneuvers under control of simulated autopilot; and presents summary and discussion of future work.

  6. Neuronal periodicity detection as a basis for the perception of consonance: a mathematical model of tonal fusion.

    PubMed

    Ebeling, Martin

    2008-10-01

    A mathematical model is presented here to explain the sensation of consonance and dissonance on the basis of neuronal coding and the properties of a neuronal periodicity detection mechanism. This mathematical model makes use of physiological data from a neuronal model of periodicity analysis in the midbrain, whose operation can be described mathematically by autocorrelation functions with regard to time windows. Musical intervals produce regular firing patterns in the auditory nerve that depend on the vibration ratio of the two tones. The mathematical model makes it possible to define a measure for the degree of these regularities for each vibration ratio. It turns out that this measure value is in line with the degree of tonal fusion as described by Stumpf [Tonpsychologie (Psychology of Tones) (Knuf, Hilversum), reprinted 1965]. This finding makes it probable that tonal fusion is a consequence of certain properties of the neuronal periodicity detection mechanism. Together with strong roughness resulting from interval tones with fundamentals close together or close to the octave, this neuronal mechanism may be regarded as the basis of consonance and dissonance.

  7. Mathematical Model of Bone Regeneration in a Porous Implant

    NASA Astrophysics Data System (ADS)

    Maslov, L. B.

    2017-07-01

    A mathematical model of the reparative regeneration of bone tissue governed by the law of cell differentiation and action of an external periodic mechanical loading is presented. The model allows one to study the recovery processes of injured human locomotor system elements under a dynamic loading and to theoretically substantiate the choice of an optimum periodic impact on the defective tissues for their fastest and steady healing.

  8. Prospective Teachers' Perspectives on Mathematics Teaching and Learning: Lens for Interpreting Experiences in a Standards-Based Mathematics Course

    ERIC Educational Resources Information Center

    Chamberlin, Michelle T.

    2013-01-01

    In a mathematics course for prospective elementary teachers, we strove to model standards-based pedagogy. However, an end-of-class reflection revealed the prospective teachers were considering incorporating standards-based strategies in their future classrooms in ways different from our intent. Thus, we drew upon the framework presented by Simon,…

  9. Modeling human behavior in economics and social science.

    PubMed

    Dolfin, M; Leonida, L; Outada, N

    2017-12-01

    The complex interactions between human behaviors and social economic sciences is critically analyzed in this paper in view of possible applications of mathematical modeling as an attainable interdisciplinary approach to understand and simulate the aforementioned dynamics. The quest is developed along three steps: Firstly an overall analysis of social and economic sciences indicates the main requirements that a contribution of mathematical modeling should bring to these sciences; subsequently the focus moves to an overview of mathematical tools and to the selection of those which appear, according to the authors bias, appropriate to the modeling; finally, a survey of applications is presented looking ahead to research perspectives. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Analysis mathematical literacy skills in terms of the students’ metacognition on PISA-CPS model

    NASA Astrophysics Data System (ADS)

    Ovan; Waluya, S. B.; Nugroho, S. E.

    2018-03-01

    This research was aimed to know the effectiveness of PISA-CPS model and desceibe the mathematical literacy skills (KLM) in terms of the students’ metacognition. This study used Mixed Methods approaches with the concurrent embedded desaign. The technique of data analysis on quantitative research done analysis of lesson plan, prerequisite test, test hypotesis 1 and hypotesis test. While qualitative research done data reduction, data presentation, and drawing conclution and data verification. The subject of this study was the students of Grade Eight (VIII) of SMP Islam Sultan Agung 4 Semarang, Central Java. The writer analyzed the data with quantitative and qualitative approaches based on the metacognition of the students in low, medium and high groups. Subsequently, taken the mathematical literacy skills (KLM) from students’ metacognition in low, medium, and high . The results of the study showed that the PISA-CPS model was complete and the students’ mathematical literacy skills in terms of the students’ metacognition taught by the PISA-CPS model was higher than the expository learning. metacognitions’ students classified low hadmathematical literacy skills (KLM) less good, metacognitions’ students classified medium had mathematical literacy skills (KLM) good enough, metacognitions’ students classified high had mathematical literacy skills (KLM) very good. Based onresult analysis got conclusion that the PISA-CPS model was effective toward the students’ mathematical literacy skills (KLM). To increase the students’ mathematical literacy skills (KLM), the teachers need to provide reinforcements in the form of the exercises so that the student’s mathematical literacy was achieved at level 5 and level 6.

  11. Mathematical Models of the Common-Source and Common-Gate Amplifiers using a Metal-Ferroelectric-Semiconductor Field effect Transistor

    NASA Technical Reports Server (NTRS)

    Hunt, Mitchell; Sayyah, Rana; Mitchell, Cody; Laws, Crystal; MacLeod, Todd C.; Ho, Fat D.

    2013-01-01

    Mathematical models of the common-source and common-gate amplifiers using metal-ferroelectric- semiconductor field effect transistors (MOSFETs) are developed in this paper. The models are compared against data collected with MOSFETs of varying channel lengths and widths, and circuit parameters such as biasing conditions are varied as well. Considerations are made for the capacitance formed by the ferroelectric layer present between the gate and substrate of the transistors. Comparisons between the modeled and measured data are presented in depth as well as differences and advantages as compared to the performance of each circuit using a MOSFET.

  12. Stochastic and Deterministic Models for the Metastatic Emission Process: Formalisms and Crosslinks.

    PubMed

    Gomez, Christophe; Hartung, Niklas

    2018-01-01

    Although the detection of metastases radically changes prognosis of and treatment decisions for a cancer patient, clinically undetectable micrometastases hamper a consistent classification into localized or metastatic disease. This chapter discusses mathematical modeling efforts that could help to estimate the metastatic risk in such a situation. We focus on two approaches: (1) a stochastic framework describing metastatic emission events at random times, formalized via Poisson processes, and (2) a deterministic framework describing the micrometastatic state through a size-structured density function in a partial differential equation model. Three aspects are addressed in this chapter. First, a motivation for the Poisson process framework is presented and modeling hypotheses and mechanisms are introduced. Second, we extend the Poisson model to account for secondary metastatic emission. Third, we highlight an inherent crosslink between the stochastic and deterministic frameworks and discuss its implications. For increased accessibility the chapter is split into an informal presentation of the results using a minimum of mathematical formalism and a rigorous mathematical treatment for more theoretically interested readers.

  13. A lumped parameter mathematical model for simulation of subsonic wind tunnels

    NASA Technical Reports Server (NTRS)

    Krosel, S. M.; Cole, G. L.; Bruton, W. M.; Szuch, J. R.

    1986-01-01

    Equations for a lumped parameter mathematical model of a subsonic wind tunnel circuit are presented. The equation state variables are internal energy, density, and mass flow rate. The circuit model is structured to allow for integration and analysis of tunnel subsystem models which provide functions such as control of altitude pressure and temperature. Thus the model provides a useful tool for investigating the transient behavior of the tunnel and control requirements. The model was applied to the proposed NASA Lewis Altitude Wind Tunnel (AWT) circuit and included transfer function representations of the tunnel supply/exhaust air and refrigeration subsystems. Both steady state and frequency response data are presented for the circuit model indicating the type of results and accuracy that can be expected from the model. Transient data for closed loop control of the tunnel and its subsystems are also presented, demonstrating the model's use as a control analysis tool.

  14. Development of the Mathematical Model for Ingot Quality Forecasting with Consideration of Thermal and Physical Characteristics of Mould Powder

    NASA Astrophysics Data System (ADS)

    Anisimov, K. N.; Loginov, A. M.; Gusev, M. P.; Zarubin, S. V.; Nikonov, S. V.; Krasnov, A. V.

    2017-12-01

    This paper presents the results of physical modelling of the mould powder skull in the gap between an ingot and the mould. Based on the results obtained from this and previous works, the mathematical model of mould powder behaviour in the gap and its influence on formation of surface defects was developed. The results of modelling satisfactorily conform to the industrial data on ingot surface defects.

  15. Contrasting two models of academic self-efficacy--domain-specific versus cross-domain--in children receiving and not receiving special instruction in mathematics.

    PubMed

    Jungert, Tomas; Hesser, Hugo; Träff, Ulf

    2014-10-01

    In social cognitive theory, self-efficacy is domain-specific. An alternative model, the cross-domain influence model, would predict that self-efficacy beliefs in one domain might influence performance in other domains. Research has also found that children who receive special instruction are not good at estimating their performance. The aim was to test two models of how self-efficacy beliefs influence achievement, and to contrast children receiving special instruction in mathematics with normally-achieving children. The participants were 73 fifth-grade children who receive special instruction and 70 children who do not receive any special instruction. In year four and five, the children's skills in mathematics and reading were assessed by national curriculum tests, and in their fifth year, self-efficacy in mathematics and reading were measured. Structural equation modeling showed that in domains where children do not receive special instruction in mathematics, self-efficacy is a mediating variable between earlier and later achievement in the same domain. Achievement in mathematics was not mediated by self-efficacy in mathematics for children who receive special instruction. For normal achieving children, earlier achievement in the language domain had an influence on later self-efficacy in the mathematics domain, and self-efficacy beliefs in different domains were correlated. Self-efficacy is mostly domain specific, but may play a different role in academic performance depending on whether children receive special instruction. The results of the present study provided some support of the Cross-Domain Influence Model for normal achieving children. © 2014 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  16. Integrated Technology Rotor Methodology Assessment Workshop

    NASA Technical Reports Server (NTRS)

    Mcnulty, Michael J. (Editor); Bousman, William G. (Editor)

    1988-01-01

    The conference proceedings contains 14 formal papers and the results of two panel discussions. In addition, a transcript of discussion that followed the paper presentations and panels is included. The papers are of two kinds. The first seven papers were directed specifically to the correlation of industry and government mathematical models with data for rotorcraft stability from six experiments. The remaining 7 papers dealt with related topics in the prediction of rotor aeroelastic or aeromechanical stability. The first of the panels provided an evaluation of the correlation that was shown between the mathematical models and the experimental data. The second panel addressed the general problems of the validation of mathematical models.

  17. A simple mathematical model of society collapse applied to Easter Island

    NASA Astrophysics Data System (ADS)

    Bologna, M.; Flores, J. C.

    2008-02-01

    In this paper we consider a mathematical model for the evolution and collapse of the Easter Island society. Based on historical reports, the available primary resources consisted almost exclusively in the trees, then we describe the inhabitants and the resources as an isolated dynamical system. A mathematical, and numerical, analysis about the Easter Island community collapse is performed. In particular, we analyze the critical values of the fundamental parameters and a demographic curve is presented. The technological parameter, quantifying the exploitation of the resources, is calculated and applied to the case of another extinguished civilization (Copán Maya) confirming the consistency of the adopted model.

  18. Mathematical Model of Stress-Strain State of Curved Tube of Non-Circular Cross-Section with Account of Technological Wall Thickness Variation

    NASA Astrophysics Data System (ADS)

    Pirogov, S. P.; Ustinov, N. N.; Smolin, N. I.

    2018-05-01

    A mathematical model of the stress-strain state of a curved tube of a non-circular cross-section is presented, taking into account the technological wall thickness variation. On the basis of the semi-membrane shell theory, a system of linear differential equations describing the deformation of a tube under the effect of pressure is obtained. To solve the boundary value problem, the method of shooting is applied. The adequacy of the proposed mathematical model is verified by comparison with the experimental data and the results of the calculation of tubes by the energy method.

  19. Preface.

    PubMed

    Friedman, Avner; Lachowicz, Mirosław; Ledzewicz, Urszula; Piotrowska, Monika Joanna; Szymanska, Zuzanna

    2017-02-01

    This volume was inspired by the topics presented at the international conference "Micro and Macro Systems in Life Sciences" which was held on Jun 8-12, 2015 in Będlewo, Poland. System biology is an approach which tries to understand how micro systems, at the molecular and cellular levels, affect macro systems such as organs, tissue and populations. Thus it is not surprising that a major theme of this volume evolves around cancer and its treatment. Articles on this topic include models for tumor induced angiogenesis, without and with delays, metastatic niche of the bone marrow, drug resistance and metronomic chemotherapy, and virotherapy of glioma. Methods range from dynamical systems to optimal control. Another well represented topic of this volume is mathematical modeling in epidemiology. Mathematical approaches to modeling and control of more specific diseases like malaria, Ebola or human papillomavirus are discussed as well as a more general approaches to the SEIR, and even more general class of models in epidemiology, by using the tools of optimal control and optimization. The volume also brings up challenges in mathematical modeling of other diseases such as tuberculosis. Partial differential equations combined with numerical approaches are becoming important tools in modeling not only tumor growth and treatment, but also other diseases, such as fibrosis of the liver, and atherosclerosis and its associated blood flow dynamics, and our volume presents a state of the art approach on these topics. Understanding mathematics behind the cell motion, appearance of the special patterns in various cell populations, and age structured mutations are among topics addressed inour volume. A spatio-temporal models of synthetic genetic oscillators brings the analysis to the gene level which is the focus of much of current biological research. Mathematics can help biologists to explain the collective behavior of bacterial, a topic that is also presented here. Finally some more across the discipline topics are being addresses, which can appear as a challenge in studying problems in systems biology on all, macro, meso and micro levels. They include numerical approaches to stochastic wave equation arising in modeling Brownian motion, discrete velocity models, many particle approximations as well as very important aspect on the connection between discrete measurement and the construction of the models for various phenomena, particularly the one involving delays. With the variety of biological topics and their mathematical approaches we very much hope that the reader of the Mathematical Biosciences and Engineering will find this volume interesting and inspirational for their own research.

  20. The application of virtual prototyping methods to determine the dynamic parameters of mobile robot

    NASA Astrophysics Data System (ADS)

    Kurc, Krzysztof; Szybicki, Dariusz; Burghardt, Andrzej; Muszyńska, Magdalena

    2016-04-01

    The paper presents methods used to determine the parameters necessary to build a mathematical model of an underwater robot with a crawler drive. The parameters present in the dynamics equation will be determined by means of advanced mechatronic design tools, including: CAD/CAE software andMES modules. The virtual prototyping process is described as well as the various possible uses (design adaptability) depending on the optional accessories added to the vehicle. A mathematical model is presented to show the kinematics and dynamics of the underwater crawler robot, essential for the design stage.

  1. Mathematical modelling of clostridial acetone-butanol-ethanol fermentation.

    PubMed

    Millat, Thomas; Winzer, Klaus

    2017-03-01

    Clostridial acetone-butanol-ethanol (ABE) fermentation features a remarkable shift in the cellular metabolic activity from acid formation, acidogenesis, to the production of industrial-relevant solvents, solventogensis. In recent decades, mathematical models have been employed to elucidate the complex interlinked regulation and conditions that determine these two distinct metabolic states and govern the transition between them. In this review, we discuss these models with a focus on the mechanisms controlling intra- and extracellular changes between acidogenesis and solventogenesis. In particular, we critically evaluate underlying model assumptions and predictions in the light of current experimental knowledge. Towards this end, we briefly introduce key ideas and assumptions applied in the discussed modelling approaches, but waive a comprehensive mathematical presentation. We distinguish between structural and dynamical models, which will be discussed in their chronological order to illustrate how new biological information facilitates the 'evolution' of mathematical models. Mathematical models and their analysis have significantly contributed to our knowledge of ABE fermentation and the underlying regulatory network which spans all levels of biological organization. However, the ties between the different levels of cellular regulation are not well understood. Furthermore, contradictory experimental and theoretical results challenge our current notion of ABE metabolic network structure. Thus, clostridial ABE fermentation still poses theoretical as well as experimental challenges which are best approached in close collaboration between modellers and experimentalists.

  2. Predicting Student Academic Performance in an Engineering Dynamics Course: A Comparison of Four Types of Predictive Mathematical Models

    ERIC Educational Resources Information Center

    Huang, Shaobo; Fang, Ning

    2013-01-01

    Predicting student academic performance has long been an important research topic in many academic disciplines. The present study is the first study that develops and compares four types of mathematical models to predict student academic performance in engineering dynamics--a high-enrollment, high-impact, and core course that many engineering…

  3. A Bayesian Performance Prediction Model for Mathematics Education: A Prototypical Approach for Effective Group Composition

    ERIC Educational Resources Information Center

    Bekele, Rahel; McPherson, Maggie

    2011-01-01

    This research work presents a Bayesian Performance Prediction Model that was created in order to determine the strength of personality traits in predicting the level of mathematics performance of high school students in Addis Ababa. It is an automated tool that can be used to collect information from students for the purpose of effective group…

  4. Mathematical Practice in Textbooks Analysis: Praxeological Reference Models, the Case of Proportion

    ERIC Educational Resources Information Center

    Wijayanti, Dyana; Winsløw, Carl

    2017-01-01

    We present a new method in textbook analysis, based on so-called praxeological reference models focused on specific content at task level. This method implies that the mathematical contents of a textbook (or textbook part) is analyzed in terms of the tasks and techniques which are exposed to or demanded from readers; this can then be interpreted…

  5. A mathematical model for ethanol fermentation from oil palm trunk sap using Saccharomyces cerevisiae

    NASA Astrophysics Data System (ADS)

    Sultana, S.; Jamil, Norazaliza Mohd; Saleh, E. A. M.; Yousuf, A.; Faizal, Che Ku M.

    2017-09-01

    This paper presents a mathematical model and solution strategy of ethanol fermentation for oil palm trunk (OPT) sap by considering the effect of substrate limitation, substrate inhibition product inhibition and cell death. To investigate the effect of cell death rate on the fermentation process we extended and improved the current mathematical model. The kinetic parameters of the model were determined by nonlinear regression using maximum likelihood function. The temporal profiles of sugar, cell and ethanol concentrations were modelled by a set of ordinary differential equations, which were solved numerically by the 4th order Runge-Kutta method. The model was validated by the experimental data and the agreement between the model and experimental results demonstrates that the model is reasonable for prediction of the dynamic behaviour of the fermentation process.

  6. Current problems in applied mathematics and mathematical physics

    NASA Astrophysics Data System (ADS)

    Samarskii, A. A.

    Papers are presented on such topics as mathematical models in immunology, mathematical problems of medical computer tomography, classical orthogonal polynomials depending on a discrete variable, and boundary layer methods for singular perturbation problems in partial derivatives. Consideration is also given to the computer simulation of supernova explosion, nonstationary internal waves in a stratified fluid, the description of turbulent flows by unsteady solutions of the Navier-Stokes equations, and the reduced Galerkin method for external diffraction problems using the spline approximation of fields.

  7. Atmospheric Dispersal and Dispostion of Tephra From a Potential Volcanic Eruption at Yucca Mountain, Nevada

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    G. Keating; W.Statham

    2004-02-12

    The purpose of this model report is to provide documentation of the conceptual and mathematical model (ASHPLUME) for atmospheric dispersal and subsequent deposition of ash on the land surface from a potential volcanic eruption at Yucca Mountain, Nevada. This report also documents the ash (tephra) redistribution conceptual model. The ASHPLUME conceptual model accounts for incorporation and entrainment of waste fuel particles associated with a hypothetical volcanic eruption through the Yucca Mountain repository and downwind transport of contaminated tephra. The ASHPLUME mathematical model describes the conceptual model in mathematical terms to allow for prediction of radioactive waste/ash deposition on the groundmore » surface given that the hypothetical eruptive event occurs. This model report also describes the conceptual model for tephra redistribution from a basaltic cinder cone. Sensitivity analyses and model validation activities for the ash dispersal and redistribution models are also presented. Analyses documented in this model report will improve and clarify the previous documentation of the ASHPLUME mathematical model and its application to the Total System Performance Assessment (TSPA) for the License Application (TSPA-LA) igneous scenarios. This model report also documents the redistribution model product outputs based on analyses to support the conceptual model.« less

  8. The Effects of Using Drawings in Developing Young Children's Mathematical Word Problem Solving: A Design Experiment with Third-Grade Hungarian Students

    ERIC Educational Resources Information Center

    Csikos, Csaba; Szitanyi, Judit; Kelemen, Rita

    2012-01-01

    The present study aims to investigate the effects of a design experiment developed for third-grade students in the field of mathematics word problems. The main focus of the program was developing students' knowledge about word problem solving strategies with an emphasis on the role of visual representations in mathematical modeling. The experiment…

  9. Mathematics Low Achievement in Greece: A Multilevel Analysis of the Programme for International Student Assessment (PISA) 2012 Data

    ERIC Educational Resources Information Center

    Karakolidis, Anastasios; Pitsia, Vasiliki; Emvalotis, Anastassios

    2016-01-01

    The main aim of the present study was to carry out an in-depth examination of mathematics underperformance in Greece. By applying a binary multilevel model to the PISA 2012 data, this study investigated the factors which were linked to low achievement in mathematics. The multilevel analysis revealed that students' gender, immigration status,…

  10. A mathematical simulation model of a 1985-era tilt-rotor passenger aircraft

    NASA Technical Reports Server (NTRS)

    Mcveigh, M. A.; Widdison, C. A.

    1976-01-01

    A mathematical model for use in real-time piloted simulation of a 1985-era tilt rotor passenger aircraft is presented. The model comprises the basic six degrees-of-freedom equations of motion, and a large angle of attack representation of the airframe and rotor aerodynamics, together with equations and functions used to model turbine engine performance, aircraft control system and stability augmentation system. A complete derivation of the primary equations is given together with a description of the modeling techniques used. Data for the model is included in an appendix.

  11. Multiphysics Simulation of Welding-Arc and Nozzle-Arc System: Mathematical-Model, Solution-Methodology and Validation

    NASA Astrophysics Data System (ADS)

    Pawar, Sumedh; Sharma, Atul

    2018-01-01

    This work presents mathematical model and solution methodology for a multiphysics engineering problem on arc formation during welding and inside a nozzle. A general-purpose commercial CFD solver ANSYS FLUENT 13.0.0 is used in this work. Arc formation involves strongly coupled gas dynamics and electro-dynamics, simulated by solution of coupled Navier-Stoke equations, Maxwell's equations and radiation heat-transfer equation. Validation of the present numerical methodology is demonstrated with an excellent agreement with the published results. The developed mathematical model and the user defined functions (UDFs) are independent of the geometry and are applicable to any system that involves arc-formation, in 2D axisymmetric coordinates system. The high-pressure flow of SF6 gas in the nozzle-arc system resembles arc chamber of SF6 gas circuit breaker; thus, this methodology can be extended to simulate arcing phenomenon during current interruption.

  12. Nonconvex Model of Material Growth: Mathematical Theory

    NASA Astrophysics Data System (ADS)

    Ganghoffer, J. F.; Plotnikov, P. I.; Sokolowski, J.

    2018-06-01

    The model of volumetric material growth is introduced in the framework of finite elasticity. The new results obtained for the model are presented with complete proofs. The state variables include the deformations, temperature and the growth factor matrix function. The existence of global in time solutions for the quasistatic deformations boundary value problem coupled with the energy balance and the evolution of the growth factor is shown. The mathematical results can be applied to a wide class of growth models in mechanics and biology.

  13. A Mathematical Model of the Thermo-Anemometric Flowmeter

    PubMed Central

    Korobiichuk, Igor; Bezvesilna, Olena; Ilchenko, Andriі; Shadura, Valentina; Nowicki, Michał; Szewczyk, Roman

    2015-01-01

    A thermo-anemometric flowmeter design and the principles of its work are presented in the article. A mathematical model of the temperature field in a stream of biofuel is proposed. This model allows one to determine the fuel consumption with high accuracy. Numerical modeling of the heater heat balance in the fuel flow of a thermo-anemometric flowmeter is conducted and the results are analyzed. Methods for increasing the measurement speed and accuracy of a thermo-anemometric flowmeter are proposed. PMID:26378535

  14. A Mathematical Model of the Thermo-Anemometric Flowmeter.

    PubMed

    Korobiichuk, Igor; Bezvesilna, Olena; Ilchenko, Andriі; Shadura, Valentina; Nowicki, Michał; Szewczyk, Roman

    2015-09-11

    A thermo-anemometric flowmeter design and the principles of its work are presented in the article. A mathematical model of the temperature field in a stream of biofuel is proposed. This model allows one to determine the fuel consumption with high accuracy. Numerical modeling of the heater heat balance in the fuel flow of a thermo-anemometric flowmeter is conducted and the results are analyzed. Methods for increasing the measurement speed and accuracy of a thermo-anemometric flowmeter are proposed.

  15. Mathematical modelling of the growth of human fetus anatomical structures.

    PubMed

    Dudek, Krzysztof; Kędzia, Wojciech; Kędzia, Emilia; Kędzia, Alicja; Derkowski, Wojciech

    2017-09-01

    The goal of this study was to present a procedure that would enable mathematical analysis of the increase of linear sizes of human anatomical structures, estimate mathematical model parameters and evaluate their adequacy. Section material consisted of 67 foetuses-rectus abdominis muscle and 75 foetuses- biceps femoris muscle. The following methods were incorporated to the study: preparation and anthropologic methods, image digital acquisition, Image J computer system measurements and statistical analysis method. We used an anthropologic method based on age determination with the use of crown-rump length-CRL (V-TUB) by Scammon and Calkins. The choice of mathematical function should be based on a real course of the curve presenting growth of anatomical structure linear size Ύ in subsequent weeks t of pregnancy. Size changes can be described with a segmental-linear model or one-function model with accuracy adequate enough for clinical purposes. The interdependence of size-age is described with many functions. However, the following functions are most often considered: linear, polynomial, spline, logarithmic, power, exponential, power-exponential, log-logistic I and II, Gompertz's I and II and von Bertalanffy's function. With the use of the procedures described above, mathematical models parameters were assessed for V-PL (the total length of body) and CRL body length increases, rectus abdominis total length h, its segments hI, hII, hIII, hIV, as well as biceps femoris length and width of long head (LHL and LHW) and of short head (SHL and SHW). The best adjustments to measurement results were observed in the exponential and Gompertz's models.

  16. Fathead Minnow Steroidogenesis: In Silico Analyses Reveals Tradeoffs Between Nominal Target Efficacy and Robustness to Cross-talk

    EPA Science Inventory

    This paper presents the formulation and evaluation of a mechanistic mathematical model of fathead minnow ovarian steroidogenesis. The model presented in the present study was adpated from other models developed as part of an integrated, multi-disciplinary computational toxicolog...

  17. The structural identifiability and parameter estimation of a multispecies model for the transmission of mastitis in dairy cows with postmilking teat disinfection.

    PubMed

    White, L J; Evans, N D; Lam, T J G M; Schukken, Y H; Medley, G F; Godfrey, K R; Chappell, M J

    2002-01-01

    A mathematical model for the transmission of two interacting classes of mastitis causing bacterial pathogens in a herd of dairy cows is presented and applied to a specific data set. The data were derived from a field trial of a specific measure used in the control of these pathogens, where half the individuals were subjected to the control and in the others the treatment was discontinued. The resultant mathematical model (eight non-linear simultaneous ordinary differential equations) therefore incorporates heterogeneity in the host as well as the infectious agent and consequently the effects of control are intrinsic in the model structure. A structural identifiability analysis of the model is presented demonstrating that the scope of the novel method used allows application to high order non-linear systems. The results of a simultaneous estimation of six unknown system parameters are presented. Previous work has only estimated a subset of these either simultaneously or individually. Therefore not only are new estimates provided for the parameters relating to the transmission and control of the classes of pathogens under study, but also information about the relationships between them. We exploit the close link between mathematical modelling, structural identifiability analysis, and parameter estimation to obtain biological insights into the system modelled.

  18. Mathematics as a Conduit for Translational Research in Post-Traumatic Osteoarthritis

    PubMed Central

    Ayati, Bruce P.; Kapitanov, Georgi I.; Coleman, Mitchell C.; Anderson, Donald D.; Martin, James A.

    2016-01-01

    Biomathematical models offer a powerful method of clarifying complex temporal interactions and the relationships among multiple variables in a system. We present a coupled in silico biomathematical model of articular cartilage degeneration in response to impact and/or aberrant loading such as would be associated with injury to an articular joint. The model incorporates fundamental biological and mechanical information obtained from explant and small animal studies to predict post-traumatic osteoarthritis (PTOA) progression, with an eye toward eventual application in human patients. In this sense, we refer to the mathematics as a “conduit of translation”. The new in silico framework presented in this paper involves a biomathematical model for the cellular and biochemical response to strains computed using finite element analysis. The model predicts qualitative responses presently, utilizing system parameter values largely taken from the literature. To contribute to accurate predictions, models need to be accurately parameterized with values that are based on solid science. We discuss a parameter identification protocol that will enable us to make increasingly accurate predictions of PTOA progression using additional data from smaller scale explant and small animal assays as they become available. By distilling the data from the explant and animal assays into parameters for biomathematical models, mathematics can translate experimental data to clinically relevant knowledge. PMID:27653021

  19. Geometric model of pseudo-distance measurement in satellite location systems

    NASA Astrophysics Data System (ADS)

    Panchuk, K. L.; Lyashkov, A. A.; Lyubchinov, E. V.

    2018-04-01

    The existing mathematical model of pseudo-distance measurement in satellite location systems does not provide a precise solution of the problem, but rather an approximate one. The existence of such inaccuracy, as well as bias in measurement of distance from satellite to receiver, results in inaccuracy level of several meters. Thereupon, relevance of refinement of the current mathematical model becomes obvious. The solution of the system of quadratic equations used in the current mathematical model is based on linearization. The objective of the paper is refinement of current mathematical model and derivation of analytical solution of the system of equations on its basis. In order to attain the objective, geometric analysis is performed; geometric interpretation of the equations is given. As a result, an equivalent system of equations, which allows analytical solution, is derived. An example of analytical solution implementation is presented. Application of analytical solution algorithm to the problem of pseudo-distance measurement in satellite location systems allows to improve the accuracy such measurements.

  20. Software and mathematical support of Kazakhstani star tracker

    NASA Astrophysics Data System (ADS)

    Akhmedov, D.; Yelubayev, S.; Ten, V.; Bopeyev, T.; Alipbayev, K.; Sukhenko, A.

    2016-10-01

    Currently the specialists of Kazakhstan have been developing the star tracker that is further planned to use on Kazakhstani satellites of various purposes. At the first stage it has been developed the experimental model of star tracker that has following characteristics: field of view 20°, update frequency 2 Hz, exclusion angle 40°, accuracy of attitude determination of optical axis/around optical axis 15/50 arcsec. Software and mathematical support are the most high technology parts of star tracker. The results of software and mathematical support development of experimental model of Kazakhstani star tracker are represented in this article. In particular, there are described the main mathematical models and algorithms that have been used as a basis for program units of preliminary image processing of starry sky, stars identification and star tracker attitude determination. The results of software and mathematical support testing with the help of program simulation complex using various configurations of defects including image sensor noises, point spread function modeling, optical system distortion up to 2% are presented. Analysis of testing results has shown that accuracy of attitude determination of star tracker is within the permissible range

  1. Polynomial algebra of discrete models in systems biology.

    PubMed

    Veliz-Cuba, Alan; Jarrah, Abdul Salam; Laubenbacher, Reinhard

    2010-07-01

    An increasing number of discrete mathematical models are being published in Systems Biology, ranging from Boolean network models to logical models and Petri nets. They are used to model a variety of biochemical networks, such as metabolic networks, gene regulatory networks and signal transduction networks. There is increasing evidence that such models can capture key dynamic features of biological networks and can be used successfully for hypothesis generation. This article provides a unified framework that can aid the mathematical analysis of Boolean network models, logical models and Petri nets. They can be represented as polynomial dynamical systems, which allows the use of a variety of mathematical tools from computer algebra for their analysis. Algorithms are presented for the translation into polynomial dynamical systems. Examples are given of how polynomial algebra can be used for the model analysis. alanavc@vt.edu Supplementary data are available at Bioinformatics online.

  2. Price-Dynamics of Shares and Bohmian Mechanics: Deterministic or Stochastic Model?

    NASA Astrophysics Data System (ADS)

    Choustova, Olga

    2007-02-01

    We apply the mathematical formalism of Bohmian mechanics to describe dynamics of shares. The main distinguishing feature of the financial Bohmian model is the possibility to take into account market psychology by describing expectations of traders by the pilot wave. We also discuss some objections (coming from conventional financial mathematics of stochastic processes) against the deterministic Bohmian model. In particular, the objection that such a model contradicts to the efficient market hypothesis which is the cornerstone of the modern market ideology. Another objection is of pure mathematical nature: it is related to the quadratic variation of price trajectories. One possibility to reply to this critique is to consider the stochastic Bohm-Vigier model, instead of the deterministic one. We do this in the present note.

  3. A Mathematical Model for the Exhaust Gas Temperature Profile of a Diesel Engine

    NASA Astrophysics Data System (ADS)

    Brito, C. H. G.; Maia, C. B.; Sodré, J. R.

    2015-09-01

    This work presents a heat transfer model for the exhaust gas of a diesel power generator to determine the gas temperature profile in the exhaust pipe. The numerical methodology to solve the mathematical model was developed using a finite difference method approach for energy equation resolution and determination of temperature profiles considering turbulent fluid flow and variable fluid properties. The simulation was carried out for engine operation under loads from 0 kW to 40 kW. The model was compared with results obtained using the multidimensional Ansys CFX software, which was applied to solve the governor equations of turbulent fluid flow. The results for the temperature profiles in the exhaust pipe show a good proximity between the mathematical model developed and the multidimensional software.

  4. Mathematical modelling of risk reduction in reinsurance

    NASA Astrophysics Data System (ADS)

    Balashov, R. B.; Kryanev, A. V.; Sliva, D. E.

    2017-01-01

    The paper presents a mathematical model of efficient portfolio formation in the reinsurance markets. The presented approach provides the optimal ratio between the expected value of return and the risk of yield values below a certain level. The uncertainty in the return values is conditioned by use of expert evaluations and preliminary calculations, which result in expected return values and the corresponding risk levels. The proposed method allows for implementation of computationally simple schemes and algorithms for numerical calculation of the numerical structure of the efficient portfolios of reinsurance contracts of a given insurance company.

  5. Mathematical modeling of infectious disease dynamics

    PubMed Central

    Siettos, Constantinos I.; Russo, Lucia

    2013-01-01

    Over the last years, an intensive worldwide effort is speeding up the developments in the establishment of a global surveillance network for combating pandemics of emergent and re-emergent infectious diseases. Scientists from different fields extending from medicine and molecular biology to computer science and applied mathematics have teamed up for rapid assessment of potentially urgent situations. Toward this aim mathematical modeling plays an important role in efforts that focus on predicting, assessing, and controlling potential outbreaks. To better understand and model the contagious dynamics the impact of numerous variables ranging from the micro host–pathogen level to host-to-host interactions, as well as prevailing ecological, social, economic, and demographic factors across the globe have to be analyzed and thoroughly studied. Here, we present and discuss the main approaches that are used for the surveillance and modeling of infectious disease dynamics. We present the basic concepts underpinning their implementation and practice and for each category we give an annotated list of representative works. PMID:23552814

  6. A mathematical model of transport and regional uptake of radioactive gases in the human respiratory system

    NASA Astrophysics Data System (ADS)

    Baek, Inseok

    The purpose of this research is to describe the development of a mathematical model of diffusion, convection, and lateral transport into the airway wall and alveolar absorption for inhaled radioactive gases in the human conductive and respiratory airways based on a Single Path Trumpet-bell model (SPM). Mathematical simulation models have been used successfully to study transport, absorption into the blood through alveoli, and lung tissue uptake of soluble and nonreactive radioactive gases. Results from such simulations also show clearly that inhaled radioactive gases are absorbed into the lung tissues as well as into the blood through the alveoli. In contrast to previous reports in the literature, the present study found that blood uptake through alveoli is much greater than that calculated previously. Regional depositions in the lung from inhaled radioactive gases are presented as the result of this simulation. The committed effective dose to lung tissue due to submersion in radioactive clouds has been newly defined using the results of this simulation.

  7. Mathematical model for prediction of efficiency indicators of educational activity in high school

    NASA Astrophysics Data System (ADS)

    Tikhonova, O. M.; Kushnikov, V. A.; Fominykh, D. S.; Rezchikov, A. F.; Ivashchenko, V. A.; Bogomolov, A. S.; Filimonyuk, L. Yu; Dolinina, O. N.; Kushnikov, O. V.; Shulga, T. E.; Tverdokhlebov, V. A.

    2018-05-01

    The quality of high school is a current problem all over the world. The paper presents the system dedicated to predicting the accreditation indicators of technical universities based on J. Forrester mechanism of system dynamics. The mathematical model is developed for prediction of efficiency indicators of the educational activity and is based on the apparatus of nonlinear differential equations.

  8. Use of Interactive Whiteboard in the Mathematics Classroom: Students' Perceptions within the Framework of the Technology Acceptance Model

    ERIC Educational Resources Information Center

    Önal, Nezih

    2017-01-01

    The purpose of the present research was to reveal students' perceptions regarding the use of the interactive whiteboard in the mathematics classroom within the framework of the Technology Acceptance Model. Semi-structured interviews were performed with 58 secondary school students (5th, 6th, 7th, and 8th grades) to collect data. The data obtained…

  9. Long Term Persistence of Preschool Intervention on Children's Mathematical Development: Results from the German Model Project "Kindergarten of the Future in Bavaria"

    ERIC Educational Resources Information Center

    Lehrl, Simone; Kluczniok, Katharina; Rossbach, Hans-Guenther; Anders, Yvonne

    2017-01-01

    The present study examines how attending the German model project "Kindergarten of the Future in Bavaria" (KiDZ), which provided 138 children (aged 3 to 6) with traditional preschool stimulation combined with cognitive and domain-specific stimulation, is associated with children's competencies in mathematics over time to age 12 compared…

  10. Determination of Flow Direction with Pressure Probes.

    DTIC Science & Technology

    1979-07-01

    SECTION NUMBER I INTRODUCTION .......... .. ...................... 1 II A MATHEMATICAL MODEL OF PROBE AERODYNAMIC BEHAVIOR . . 4 2.1 Objectives...also postulated. 3 SECTION II A MATHEMATICAL MODEL OF PROBE AERODYNAMIC BEHAVIOR 2. 1 Objectives The objective of an aerodynamic probe - in the present...characLerizaLion of prode behavior , they are not capable of replacing individual probe caiibrarions. Tis is due to the limitations of the derivation itself, i.e

  11. Mechanics of train collision

    DOT National Transportation Integrated Search

    1976-04-30

    A simple and a more detailed mathematical model for the simulation of train collisions are presented. The study presents considerable insight as to the causes and consequences of train motions on impact. Comparison of model predictions with two full ...

  12. Brief Report: Preliminary Proposal of a Conceptual Model of a Digital Environment for Developing Mathematical Reasoning in Students with Autism Spectrum Disorders.

    PubMed

    Santos, Maria Isabel; Breda, Ana; Almeida, Ana Margarida

    2015-08-01

    There is clear evidence that in typically developing children reasoning and sense-making are essential in all mathematical learning and understanding processes. In children with autism spectrum disorders (ASD), however, these become much more significant, considering their importance to successful independent living. This paper presents a preliminary proposal of a digital environment, specifically targeted to promote the development of mathematical reasoning in students with ASD. Given the diversity of ASD, the prototyping of this environment requires the study of dynamic adaptation processes and the development of activities adjusted to each user's profile. We present the results obtained during the first phase of this ongoing research, describing a conceptual model of the proposed digital environment. Guidelines for future research are also discussed.

  13. Gamma Ray Observatory (GRO) dynamics simulator requirements and mathematical specifications, revision 1

    NASA Technical Reports Server (NTRS)

    Harman, R.; Blejer, D.

    1990-01-01

    The requirements and mathematical specifications for the Gamma Ray Observatory (GRO) Dynamics Simulator are presented. The complete simulator system, which consists of the profie subsystem, simulation control and input/output subsystem, truth model subsystem, onboard computer model subsystem, and postprocessor, is described. The simulator will be used to evaluate and test the attitude determination and control models to be used on board GRO under conditions that simulate the expected in-flight environment.

  14. Mathematical modeling of radiative-conductive heat transfer in semitransparent medium with phase change

    NASA Astrophysics Data System (ADS)

    Savvinova, Nadezhda A.; Sleptsov, Semen D.; Rubtsov, Nikolai A.

    2017-11-01

    A mathematical phase change model is a formulation of the Stefan problem. Various formulations of the Stefan problem modeling of radiative-conductive heat transfer during melting or solidification of a semitransparent material are presented. Analysis of numerical results show that the radiative heat transfer has a significant effect on temperature distributions during melting (solidification) of the semitransparent material. In this paper conditions for application of various statements of the Stefan problem are analyzed.

  15. Predicting electroporation of cells in an inhomogeneous electric field based on mathematical modeling and experimental CHO-cell permeabilization to propidium iodide determination.

    PubMed

    Dermol, Janja; Miklavčič, Damijan

    2014-12-01

    High voltage electric pulses cause electroporation of the cell membrane. Consequently, flow of the molecules across the membrane increases. In our study we investigated possibility to predict the percentage of the electroporated cells in an inhomogeneous electric field on the basis of the experimental results obtained when cells were exposed to a homogeneous electric field. We compared and evaluated different mathematical models previously suggested by other authors for interpolation of the results (symmetric sigmoid, asymmetric sigmoid, hyperbolic tangent and Gompertz curve). We investigated the density of the cells and observed that it has the most significant effect on the electroporation of the cells while all four of the mathematical models yielded similar results. We were able to predict electroporation of cells exposed to an inhomogeneous electric field based on mathematical modeling and using mathematical formulations of electroporation probability obtained experimentally using exposure to the homogeneous field of the same density of cells. Models describing cell electroporation probability can be useful for development and presentation of treatment planning for electrochemotherapy and non-thermal irreversible electroporation. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Mathematical modeling of tomographic scanning of cylindrically shaped test objects

    NASA Astrophysics Data System (ADS)

    Kapranov, B. I.; Vavilova, G. V.; Volchkova, A. V.; Kuznetsova, I. S.

    2018-05-01

    The paper formulates mathematical relationships that describe the length of the radiation absorption band in the test object for the first generation tomographic scan scheme. A cylindrically shaped test object containing an arbitrary number of standard circular irregularities is used to perform mathematical modeling. The obtained mathematical relationships are corrected with respect to chemical composition and density of the test object material. The equations are derived to calculate the resulting attenuation radiation from cobalt-60 isotope when passing through the test object. An algorithm to calculate the radiation flux intensity is provided. The presented graphs describe the dependence of the change in the γ-quantum flux intensity on the change in the radiation source position and the scanning angle of the test object.

  17. Mathematical model of the glucose-insulin regulatory system: From the bursting electrical activity in pancreatic β-cells to the glucose dynamics in the whole body

    NASA Astrophysics Data System (ADS)

    Han, Kyungreem; Kang, Hyuk; Choi, M. Y.; Kim, Jinwoong; Lee, Myung-Shik

    2012-10-01

    A theoretical approach to the glucose-insulin regulatory system is presented. By means of integrated mathematical modeling and extensive numerical simulations, we probe the cell-level dynamics of the membrane potential, intracellular Ca2+ concentration, and insulin secretion in pancreatic β-cells, together with the whole-body level glucose-insulin dynamics in the liver, brain, muscle, and adipose tissues. In particular, the three oscillatory modes of insulin secretion are reproduced successfully. Such comprehensive mathematical modeling may provide a theoretical basis for the simultaneous assessment of the β-cell function and insulin resistance in clinical examination.

  18. Global stability and periodic solution of the viral dynamics

    NASA Astrophysics Data System (ADS)

    Song, Xinyu; Neumann, Avidan U.

    2007-05-01

    It is well known that the mathematical models provide very important information for the research of human immunodeficiency virus-type 1 and hepatitis C virus (HCV). However, the infection rate of almost all mathematical models is linear. The linearity shows the simple interaction between the T cells and the viral particles. In this paper, we consider the classical mathematical model with saturation response of the infection rate. By stability analysis we obtain sufficient conditions on the parameters for the global stability of the infected steady state and the infection-free steady state. We also obtain the conditions for the existence of an orbitally asymptotically stable periodic solution. Numerical simulations are presented to illustrate the results.

  19. Techniques for modeling the reliability of fault-tolerant systems with the Markov state-space approach

    NASA Technical Reports Server (NTRS)

    Butler, Ricky W.; Johnson, Sally C.

    1995-01-01

    This paper presents a step-by-step tutorial of the methods and the tools that were used for the reliability analysis of fault-tolerant systems. The approach used in this paper is the Markov (or semi-Markov) state-space method. The paper is intended for design engineers with a basic understanding of computer architecture and fault tolerance, but little knowledge of reliability modeling. The representation of architectural features in mathematical models is emphasized. This paper does not present details of the mathematical solution of complex reliability models. Instead, it describes the use of several recently developed computer programs SURE, ASSIST, STEM, and PAWS that automate the generation and the solution of these models.

  20. Mathematical Modeling of Ni/H2 and Li-Ion Batteries

    NASA Technical Reports Server (NTRS)

    Weidner, John W.; White, Ralph E.; Dougal, Roger A.

    2001-01-01

    The modelling effort outlined in this viewgraph presentation encompasses the following topics: 1) Electrochemical Deposition of Nickel Hydroxide; 2) Deposition rates of thin films; 3) Impregnation of porous electrodes; 4) Experimental Characterization of Nickel Hydroxide; 5) Diffusion coefficients of protons; 6) Self-discharge rates (i.e., oxygen-evolution kinetics); 7) Hysteresis between charge and discharge; 8) Capacity loss on cycling; 9) Experimental Verification of the Ni/H2 Battery Model; 10) Mathematical Modeling Li-Ion Batteries; 11) Experimental Verification of the Li-Ion Battery Model; 11) Integrated Power System Models for Satellites; and 12) Experimental Verification of Integrated-Systems Model.

  1. A survey on hysteresis modeling, identification and control

    NASA Astrophysics Data System (ADS)

    Hassani, Vahid; Tjahjowidodo, Tegoeh; Do, Thanh Nho

    2014-12-01

    The various mathematical models for hysteresis such as Preisach, Krasnosel'skii-Pokrovskii (KP), Prandtl-Ishlinskii (PI), Maxwell-Slip, Bouc-Wen and Duhem are surveyed in terms of their applications in modeling, control and identification of dynamical systems. In the first step, the classical formalisms of the models are presented to the reader, and more broadly, the utilization of the classical models is considered for development of more comprehensive models and appropriate controllers for corresponding systems. In addition, the authors attempt to encourage the reader to follow the existing mathematical models of hysteresis to resolve the open problems.

  2. Mathematical modelling of intra-aortic balloon pump.

    PubMed

    Abdolrazaghi, Mona; Navidbakhsh, Mahdi; Hassani, Kamran

    2010-10-01

    Ischemic heart diseases now afflict thousands of Iranians and are the major cause of death in many industrialised countries. Mathematical modelling of an intra-aortic balloon pump (IABP) could provide a better understanding of its performance and help to represent blood flow and pressure in systemic arteries before and after inserting the pump. A mathematical modelling of the whole cardiovascular system was formulated using MATLAB software. The block diagram of the model consists of 43 compartments. All the anatomical data was extracted from the physiological references. In the next stage, myocardial infarction (MI) was induced in the model by decreasing the contractility of the left ventricle. The IABP was mathematically modelled and inserted in the model in the thoracic aorta I artery just before the descending aorta. The effects of IABP on MI were studied using the mathematical model. The normal operation of the cardiovascular system was studied firstly. The pressure-time graphs of the ventricles, atriums, aorta, pulmonary system, capillaries and arterioles were obtained. The volume-time curve of the left ventricle was also presented. The pressure-time curves of the left ventricle and thoracic aorta I were obtained for normal, MI, and inserted IABP conditions. Model verification was performed by comparing the simulation results with the clinical observations reported in the literature. IABP can be described by a theoretical model. Our model representing the cardiovascular system is capable of showing the effects of different pathologies such as MI and we have shown that MI effects can be reduced using IABP in accordance with the modelling results. The mathematical model should serve as a useful tool to simulate and better understand cardiovascular operation in normal and pathological conditions.

  3. A VARIABLE REACTIVITY MODEL FOR ION BINDING TO ENVIRONMENTAL SORBENTS

    EPA Science Inventory

    The conceptual and mathematical basis for a new general-composite modeling approach for ion binding to environmental sorbents is presented. The work extends the Simple Metal Sorption (SiMS) model previously presented for metal and proton binding to humic substances. A surface com...

  4. A user-friendly mathematical modelling web interface to assist local decision making in the fight against drug-resistant tuberculosis.

    PubMed

    Ragonnet, Romain; Trauer, James M; Denholm, Justin T; Marais, Ben J; McBryde, Emma S

    2017-05-30

    Multidrug-resistant and rifampicin-resistant tuberculosis (MDR/RR-TB) represent an important challenge for global tuberculosis (TB) control. The high rates of MDR/RR-TB observed among re-treatment cases can arise from diverse pathways: de novo amplification during initial treatment, inappropriate treatment of undiagnosed MDR/RR-TB, relapse despite appropriate treatment, or reinfection with MDR/RR-TB. Mathematical modelling allows quantification of the contribution made by these pathways in different settings. This information provides valuable insights for TB policy-makers, allowing better contextualised solutions. However, mathematical modelling outputs need to consider local data and be easily accessible to decision makers in order to improve their usefulness. We present a user-friendly web-based modelling interface, which can be used by people without technical knowledge. Users can input their own parameter values and produce estimates for their specific setting. This innovative tool provides easy access to mathematical modelling outputs that are highly relevant to national TB control programs. In future, the same approach could be applied to a variety of modelling applications, enhancing local decision making.

  5. Ancient Paradoxes Can Extend Mathematical Thinking

    ERIC Educational Resources Information Center

    Czocher, Jennifer A.; Moss, Diana L.

    2017-01-01

    This article presents the Snail problem, a relatively simple challenge about motion that offers engaging extensions involving the notion of infinity. It encourages students in grades 5-9 to connect mathematics learning to logic, history, and philosophy through analyzing the problem, making sense of quantitative relationships, and modeling with…

  6. Separating Cognitive and Content Domains in Mathematical Competence

    ERIC Educational Resources Information Center

    Harks, Birgit; Klieme, Eckhard; Hartig, Johannes; Leiss, Dominik

    2014-01-01

    The present study investigates the empirical separability of mathematical (a) content domains, (b) cognitive domains, and (c) content-specific cognitive domains. There were 122 items representing two content domains (linear equations vs. theorem of Pythagoras) combined with two cognitive domains (modeling competence vs. technical competence)…

  7. Practical Effects of Classwide Mathematics Intervention

    ERIC Educational Resources Information Center

    VanDerHeyden, Amanda M.; Codding, Robin S.

    2015-01-01

    The current article presents additional analyses of a classwide mathematics intervention, from a previously reported randomized controlled trial, to offer new information about the treatment and to demonstrate the utility of different types of effect sizes. Multilevel modeling was used to examine treatment effects by race, sex, socioeconomic…

  8. Key Concept Mathematics and Management Science Models

    ERIC Educational Resources Information Center

    Macbeth, Thomas G.; Dery, George C.

    1973-01-01

    The presentation of topics in calculus and matrix algebra to second semester freshmen along with a treatment of exponential and power functions would permit them to cope with a significant portion of the mathematical concepts that comprise the essence of several disciplines in a business school curriculum. (Author)

  9. Assessment of Student Memo Assignments in Management Science

    ERIC Educational Resources Information Center

    Williams, Julie Ann Stuart; Stanny, Claudia J.; Reid, Randall C.; Hill, Christopher J.; Rosa, Katie Martin

    2015-01-01

    Frequently in Management Science courses, instructors focus primarily on teaching students the mathematics of linear programming models. However, the ability to discuss mathematical expressions in business terms is an important professional skill. The authors present an analysis of student abilities to discuss management science concepts through…

  10. Mathematical modelling of radiotherapy strategies for early breast cancer.

    PubMed

    Enderling, Heiko; Anderson, Alexander R A; Chaplain, Mark A J; Munro, Alastair J; Vaidya, Jayant S

    2006-07-07

    Targeted intraoperative radiotherapy (Targit) is a new concept of partial breast irradiation where single fraction radiotherapy is delivered directly to the tumour bed. Apart from logistic advantages, this strategy minimizes the risk of missing the tumour bed and avoids delay between surgery and radiotherapy. It is presently being compared with the standard fractionated external beam radiotherapy (EBRT) in randomized trials. In this paper we present a mathematical model for the growth and invasion of a solid tumour into a domain of tissue (in this case breast tissue), and then a model for surgery and radiation treatment of this tumour. We use the established linear-quadratic (LQ) model to compute the survival probabilities for both tumour cells and irradiated breast tissue and then simulate the effects of conventional EBRT and Targit. True local recurrence of the tumour could arise either from stray tumour cells, or the tumour bed that harbours morphologically normal cells having a predisposition to genetic changes, such as a loss of heterozygosity (LOH) in genes that are crucial for tumourigenesis, e.g. tumour suppressor genes (TSGs). Our mathematical model predicts that the single high dose of radiotherapy delivered by Targit would result in eliminating all these sources of recurrence, whereas the fractionated EBRT would eliminate stray tumour cells, but allow (by virtue of its very schedule) the cells with LOH in TSGs or cell-cycle checkpoint genes to pass on low-dose radiation-induced DNA damage and consequently mutations that may favour the development of a new tumour. The mathematical model presented here is an initial attempt to model a biologically complex phenomenon that has until now received little attention in the literature and provides a 'proof of principle' that it is possible to produce clinically testable hypotheses on the effects of different approaches of radiotherapy for breast cancer.

  11. Mathematical modeling of a nickel-cadmium battery

    NASA Technical Reports Server (NTRS)

    Fan, Deyuan; White, Ralph E.

    1991-01-01

    Extensions are presented for a mathematical model of an Ni-CD cell (Fan and White, 1991). These extensions consist of intercalation thermodynamics for the nickel electrode and oxygen generation and reduction reactions during charge and overcharge. The simulated results indicate that intercalation may be important in the nickel electrode and that including the oxygen reactions provides a means of predicting the efficiency of the cell on charge and discharge.

  12. Mathematical analysis techniques for modeling the space network activities

    NASA Technical Reports Server (NTRS)

    Foster, Lisa M.

    1992-01-01

    The objective of the present work was to explore and identify mathematical analysis techniques, and in particular, the use of linear programming. This topic was then applied to the Tracking and Data Relay Satellite System (TDRSS) in order to understand the space network better. Finally, a small scale version of the system was modeled, variables were identified, data was gathered, and comparisons were made between actual and theoretical data.

  13. Research on an augmented Lagrangian penalty function algorithm for nonlinear programming

    NASA Technical Reports Server (NTRS)

    Frair, L.

    1978-01-01

    The augmented Lagrangian (ALAG) Penalty Function Algorithm for optimizing nonlinear mathematical models is discussed. The mathematical models of interest are deterministic in nature and finite dimensional optimization is assumed. A detailed review of penalty function techniques in general and the ALAG technique in particular is presented. Numerical experiments are conducted utilizing a number of nonlinear optimization problems to identify an efficient ALAG Penalty Function Technique for computer implementation.

  14. Mathematics and engineering in real life through mathematical competitions

    NASA Astrophysics Data System (ADS)

    More, M.

    2018-02-01

    We bring out an experience of organizing mathematical competitions that can be used as a medium to motivate the student and teacher minds in new directions of thinking. This can contribute to fostering research, innovation and provide a hands-on experience of mathematical concepts with the real world. Mathematical competitions can be used to build curiosity and give an understanding of mathematical applications in real life. Participation in the competition has been classified under four broad categories. Student can showcase their findings in various forms of expression like model, poster, soft presentation, animation, live performance, art and poetry. The basic focus of the competition is on using open source computation tools and modern technology, to emphasize the relationship of mathematical concepts with engineering applications in real life.

  15. Thermal Network Modelling Handbook

    NASA Technical Reports Server (NTRS)

    1972-01-01

    Thermal mathematical modelling is discussed in detail. A three-fold purpose was established: (1) to acquaint the new user with the terminology and concepts used in thermal mathematical modelling, (2) to present the more experienced and occasional user with quick formulas and methods for solving everyday problems, coupled with study cases which lend insight into the relationships that exist among the various solution techniques and parameters, and (3) to begin to catalog in an orderly fashion the common formulas which may be applied to automated conversational language techniques.

  16. Atmosphere Behavior in Gas-Closed Mouse-Algal Systems: An Experimental and Modelling Study

    NASA Technical Reports Server (NTRS)

    Averner, M. M.; Moore, B., III; Bartholomew, I.; Wharton, R.

    1985-01-01

    A dual approach of mathematical modelling and laboratory experimentation aimed at examining the gas exchange characteristics of artificial animal/plant systems closed to the ambient atmosphere was initiated. The development of control techniques and management strategies for maintaining the atmospheric levels of carbon dioxide and oxygen at physiological levels is examined. A mathematical model simulating the atmospheric behavior in these systems was developed and an experimental gas closed system was constructed. These systems are described and preliminary results are presented.

  17. Mathematical modeling of high and low temperature heat pipes

    NASA Technical Reports Server (NTRS)

    Chi, S. W.

    1971-01-01

    Mathematical models are developed for calculating heat-transfer limitations of high-temperature heat pipes and heat-transfer limitations and temperature gradient of low temperature heat pipes. Calculated results are compared with the available experimental data from various sources to increase confidence in the present math models. Complete listings of two computer programs for high- and low-temperature heat pipes respectively are appended. These programs enable the performance of heat pipes with wrapped-screen, rectangular-groove or screen-covered rectangular-groove wick to be predicted.

  18. Mathematical modeling of bent-axis hydraulic piston motors

    NASA Technical Reports Server (NTRS)

    Bartos, R. D.

    1992-01-01

    Each of the DSN 70-m antennas uses 16 bent-axis hydraulic piston motors as part of the antenna drive system. On each of the two antenna axes, four motors are used to drive the antenna and four motors provide counter torque to remove the backlash in the antenna drive train. This article presents a mathematical model for bent-axis hydraulic piston motors. The model was developed to understand the influence of the hydraulic motors on the performance of the DSN 70-m antennas' servo control system.

  19. Numerical simulation of injection process of warm carbon dioxide into layer saturated with methane and its hydrate

    NASA Astrophysics Data System (ADS)

    Khasanov, M. K.; Stolpovsky, M. V.; Gimaltdinov, I. K.

    2018-05-01

    In this article, in a flat-one-dimensional approximation, a mathematical model is presented for injecting warm carbon dioxide into a methane hydrate formation of finite length. It is established that the model of formation of hydrate of carbon dioxide in the absence of an area saturated with methane and water, under certain parameters, leads to thermodynamic contradiction. The mathematical model of carbon dioxide injection with formation of the region saturated with methane and water is constructed.

  20. Obtaining mathematical models for assessing efficiency of dust collectors using integrated system of analysis and data management STATISTICA Design of Experiments

    NASA Astrophysics Data System (ADS)

    Azarov, A. V.; Zhukova, N. S.; Kozlovtseva, E. Yu; Dobrinsky, D. R.

    2018-05-01

    The article considers obtaining mathematical models to assess the efficiency of the dust collectors using an integrated system of analysis and data management STATISTICA Design of Experiments. The procedure for obtaining mathematical models and data processing is considered by the example of laboratory studies on a mounted installation containing a dust collector in counter-swirling flows (CSF) using gypsum dust of various fractions. Planning of experimental studies has been carried out in order to reduce the number of experiments and reduce the cost of experimental research. A second-order non-position plan (Box-Bencken plan) was used, which reduced the number of trials from 81 to 27. The order of statistical data research of Box-Benken plan using standard tools of integrated system for analysis and data management STATISTICA Design of Experiments is considered. Results of statistical data processing with significance estimation of coefficients and adequacy of mathematical models are presented.

  1. Mathematical biology modules based on modern molecular biology and modern discrete mathematics.

    PubMed

    Robeva, Raina; Davies, Robin; Hodge, Terrell; Enyedi, Alexander

    2010-01-01

    We describe an ongoing collaborative curriculum materials development project between Sweet Briar College and Western Michigan University, with support from the National Science Foundation. We present a collection of modules under development that can be used in existing mathematics and biology courses, and we address a critical national need to introduce students to mathematical methods beyond the interface of biology with calculus. Based on ongoing research, and designed to use the project-based-learning approach, the modules highlight applications of modern discrete mathematics and algebraic statistics to pressing problems in molecular biology. For the majority of projects, calculus is not a required prerequisite and, due to the modest amount of mathematical background needed for some of the modules, the materials can be used for an early introduction to mathematical modeling. At the same time, most modules are connected with topics in linear and abstract algebra, algebraic geometry, and probability, and they can be used as meaningful applied introductions into the relevant advanced-level mathematics courses. Open-source software is used to facilitate the relevant computations. As a detailed example, we outline a module that focuses on Boolean models of the lac operon network.

  2. Mathematical Biology Modules Based on Modern Molecular Biology and Modern Discrete Mathematics

    PubMed Central

    Davies, Robin; Hodge, Terrell; Enyedi, Alexander

    2010-01-01

    We describe an ongoing collaborative curriculum materials development project between Sweet Briar College and Western Michigan University, with support from the National Science Foundation. We present a collection of modules under development that can be used in existing mathematics and biology courses, and we address a critical national need to introduce students to mathematical methods beyond the interface of biology with calculus. Based on ongoing research, and designed to use the project-based-learning approach, the modules highlight applications of modern discrete mathematics and algebraic statistics to pressing problems in molecular biology. For the majority of projects, calculus is not a required prerequisite and, due to the modest amount of mathematical background needed for some of the modules, the materials can be used for an early introduction to mathematical modeling. At the same time, most modules are connected with topics in linear and abstract algebra, algebraic geometry, and probability, and they can be used as meaningful applied introductions into the relevant advanced-level mathematics courses. Open-source software is used to facilitate the relevant computations. As a detailed example, we outline a module that focuses on Boolean models of the lac operon network. PMID:20810955

  3. Mathematical modelling of respiratory syncytial virus (RSV): vaccination strategies and budget applications.

    PubMed

    Acedo, L; Díez-Domingo, J; Moraño, J-A; Villanueva, R-J

    2010-06-01

    We propose an age-structured mathematical model for respiratory syncytial virus in which children aged <1 year are especially considered. Real data on hospitalized children in the Spanish region of Valencia were used in order to determine some seasonal parameters of the model. Weekly predictions of the number of children aged <1 year that will be hospitalized in the following years in Valencia are presented using this model. Results are applied to estimate the regional cost of paediatric hospitalizations and to perform a cost-effectiveness analysis of possible vaccination strategies.

  4. A mathematical model for predicting cyclic voltammograms of electronically conductive polypyrrole

    NASA Technical Reports Server (NTRS)

    Yeu, Taewhan; Nguyen, Trung V.; White, Ralph E.

    1988-01-01

    Polypyrrole is an attractive polymer for use as a high-energy-density secondary battery because of its potential as an inexpensive, lightweight, and noncorrosive electrode material. A mathematical model to simulate cyclic voltammograms for polypyrrole is presented. The model is for a conductive porous electrode film on a rotating disk electrode (RDE) and is used to predict the spatial and time dependence of concentration, overpotential, and stored charge profiles within a polypyrrole film. The model includes both faradic and capacitance charge components in the total current density expression.

  5. A mathematical model for predicting cyclic voltammograms of electronically conductive polypyrrole

    NASA Technical Reports Server (NTRS)

    Yeu, Taewhan; Nguyen, Trung V.; White, Ralph E.

    1987-01-01

    Polypyrrole is an attractive polymer for use as a high-energy-density secondary battery because of its potential as an inexpensive, lightweight, and noncorrosive electrode material. A mathematical model to simulate cyclic voltammograms for polypyrrole is presented. The model is for a conductive porous electrode film on a rotating disk electrode (RDE) and is used to predict the spatial and time dependence of concentration, overpotential, and stored charge profiles within a polypyrrole film. The model includes both faradic and capacitance charge components in the total current density expression.

  6. The Proposal of a Evolutionary Strategy Generating the Data Structures Based on a Horizontal Tree for the Tests

    NASA Astrophysics Data System (ADS)

    Żukowicz, Marek; Markiewicz, Michał

    2016-09-01

    The aim of the article is to present a mathematical definition of the object model, that is known in computer science as TreeList and to show application of this model for design evolutionary algorithm, that purpose is to generate structures based on this object. The first chapter introduces the reader to the problem of presenting data using the TreeList object. The second chapter describes the problem of testing data structures based on TreeList. The third one shows a mathematical model of the object TreeList and the parameters, used in determining the utility of structures created through this model and in evolutionary strategy, that generates these structures for testing purposes. The last chapter provides a brief summary and plans for future research related to the algorithm presented in the article.

  7. Proceedings of the Annual Meeting of the International Group for the Psychology of Mathematics Education (PME) (28th, Bergen, Norway, July 14-18, 2004). Volume 3

    ERIC Educational Resources Information Center

    Hoines, Marit Johnsen, Ed.; ; Fuglestad, Anne Berit, Ed.

    2004-01-01

    This document contains the third volume of the proceedings of the 28th Annual Conference of the International Group for the Psychology of Mathematics. Conference presentations are centered around the theme "Inclusion and Diversity". A total of 65 research reports are presented here: (1) A Teacher's Model of Students Algebraic Thinking…

  8. ILS Scattering Problem and Signal Detection Model

    DOT National Transportation Integrated Search

    1972-02-01

    The construction of a mathematical model of The Instrument Landing System (ILS) multipath problem was undertaken. This report presents the theoretical basis for any such model, a critique of previous models and newly achieve developments in ILS model...

  9. The limitations of mathematical modeling in high school physics education

    NASA Astrophysics Data System (ADS)

    Forjan, Matej

    The theme of the doctoral dissertation falls within the scope of didactics of physics. Theoretical analysis of the key constraints that occur in the transmission of mathematical modeling of dynamical systems into field of physics education in secondary schools is presented. In an effort to explore the extent to which current physics education promotes understanding of models and modeling, we analyze the curriculum and the three most commonly used textbooks for high school physics. We focus primarily on the representation of the various stages of modeling in the solved tasks in textbooks and on the presentation of certain simplifications and idealizations, which are in high school physics frequently used. We show that one of the textbooks in most cases fairly and reasonably presents the simplifications, while the other two half of the analyzed simplifications do not explain. It also turns out that the vast majority of solved tasks in all the textbooks do not explicitly represent model assumptions based on what we can conclude that in high school physics the students do not develop sufficiently a sense of simplification and idealizations, which is a key part of the conceptual phase of modeling. For the introduction of modeling of dynamical systems the knowledge of students is also important, therefore we performed an empirical study on the extent to which high school students are able to understand the time evolution of some dynamical systems in the field of physics. The research results show the students have a very weak understanding of the dynamics of systems in which the feedbacks are present. This is independent of the year or final grade in physics and mathematics. When modeling dynamical systems in high school physics we also encounter the limitations which result from the lack of mathematical knowledge of students, because they don't know how analytically solve the differential equations. We show that when dealing with one-dimensional dynamical systems geometrical approach to solving differential equations is appropriate, while in dynamical systems of higher dimensions mathematical constraints are avoided by using a graphical oriented programs for modeling. Because in dealing with dynamical systems with four or more dimensions we may encounter problems in numerical solving, we also show how to overcome them. In the case of electrostatic pendulum we show the process of modeling the real dynamical system and we put a particular emphasize on the different phases of modeling and on the way of overcoming constraints on which we encounter in the development of the model.

  10. Geometry and Education in the Internet Age.

    ERIC Educational Resources Information Center

    Kortenkamp, Ulrich H.; Richter-Gebert, Jurgen

    This paper discusses the requirements of Interactive Geometry Systems (IGSs) and how they can be fulfilled, explains how a geometry tool can benefit from the Internet, and presents Cinderella's Cafe. Cinderella's Cafe is a new IGS with a high mathematical background that uses the most general mathematical models whenever possible, is highly…

  11. Using Financial Calculators in a Business Mathematics Course.

    ERIC Educational Resources Information Center

    Heller, William H.; Taylor, Monty B.

    2000-01-01

    Discusses the authors' experiences with integrating financial calculators into a business mathematics course. Presents a brief overview of the operation of financial calculators, reviews some of the more common models, discusses how to use the equation solver utility on other calculators to emulate a financial calculator, and explores the…

  12. Cellular automata-based modelling and simulation of biofilm structure on multi-core computers.

    PubMed

    Skoneczny, Szymon

    2015-01-01

    The article presents a mathematical model of biofilm growth for aerobic biodegradation of a toxic carbonaceous substrate. Modelling of biofilm growth has fundamental significance in numerous processes of biotechnology and mathematical modelling of bioreactors. The process following double-substrate kinetics with substrate inhibition proceeding in a biofilm has not been modelled so far by means of cellular automata. Each process in the model proposed, i.e. diffusion of substrates, uptake of substrates, growth and decay of microorganisms and biofilm detachment, is simulated in a discrete manner. It was shown that for flat biofilm of constant thickness, the results of the presented model agree with those of a continuous model. The primary outcome of the study was to propose a mathematical model of biofilm growth; however a considerable amount of focus was also placed on the development of efficient algorithms for its solution. Two parallel algorithms were created, differing in the way computations are distributed. Computer programs were created using OpenMP Application Programming Interface for C++ programming language. Simulations of biofilm growth were performed on three high-performance computers. Speed-up coefficients of computer programs were compared. Both algorithms enabled a significant reduction of computation time. It is important, inter alia, in modelling and simulation of bioreactor dynamics.

  13. Stability analysis for a delay differential equations model of a hydraulic turbine speed governor

    NASA Astrophysics Data System (ADS)

    Halanay, Andrei; Safta, Carmen A.; Dragoi, Constantin; Piraianu, Vlad F.

    2017-01-01

    The paper aims to study the dynamic behavior of a speed governor for a hydraulic turbine using a mathematical model. The nonlinear mathematical model proposed consists in a system of delay differential equations (DDE) to be compared with already established mathematical models of ordinary differential equations (ODE). A new kind of nonlinearity is introduced as a time delay. The delays can characterize different running conditions of the speed governor. For example, it is considered that spool displacement of hydraulic amplifier might be blocked due to oil impurities in the oil supply system and so the hydraulic amplifier has a time delay in comparison to the time control. Numerical simulations are presented in a comparative manner. A stability analysis of the hydraulic control system is performed, too. Conclusions of the dynamic behavior using the DDE model of a hydraulic turbine speed governor are useful in modeling and controlling hydropower plants.

  14. Design and mathematical analysis of a three-mirror X-ray telescope based on ATM S-056 X-ray telescope hardware

    NASA Technical Reports Server (NTRS)

    Foreman, J. W., Jr.; Cardone, J. M.

    1973-01-01

    The mathematical design of the aspheric third mirror for the three-mirror X-ray telescope (TMXRT) is presented, along with the imaging characteristics of the telescope obtained by a ray trace analysis. The present design effort has been directed entirely toward obtaining an aspheric third mirror which will be compatible with existing S-056 paraboloidal-hyperboloidal mirrors. This compatability will facilitate the construction of a prototype model of the TMXRT, since it will only be necessary to fabricate one new mirror in order to obtain a working model.

  15. Application of the Refined Integral Method in the mathematical modeling of drug delivery from one-layer torus-shaped devices.

    PubMed

    Helbling, Ignacio M; Ibarra, Juan C D; Luna, Julio A

    2012-02-28

    A mathematical modeling of controlled release of drug from one-layer torus-shaped devices is presented. Analytical solutions based on Refined Integral Method (RIM) are derived. The validity and utility of the model are ascertained by comparison of the simulation results with matrix-type vaginal rings experimental release data reported in the literature. For the comparisons, the pair-wise procedure is used to measure quantitatively the fit of the theoretical predictions to the experimental data. A good agreement between the model prediction and the experimental data is observed. A comparison with a previously reported model is also presented. More accurate results are achieved for small A/C(s) ratios. Copyright © 2011 Elsevier B.V. All rights reserved.

  16. Mathematical Modelling of Bacterial Populations in Bio-remediation Processes

    NASA Astrophysics Data System (ADS)

    Vasiliadou, Ioanna A.; Vayenas, Dimitris V.; Chrysikopoulos, Constantinos V.

    2011-09-01

    An understanding of bacterial behaviour concerns many field applications, such as the enhancement of water, wastewater and subsurface bio-remediation, the prevention of environmental pollution and the protection of human health. Numerous microorganisms have been identified to be able to degrade chemical pollutants, thus, a variety of bacteria are known that can be used in bio-remediation processes. In this study the development of mathematical models capable of describing bacterial behaviour considered in bio-augmentation plans, such as bacterial growth, consumption of nutrients, removal of pollutants, bacterial transport and attachment in porous media, is presented. The mathematical models may be used as a guide in designing and assessing the conditions under which areas contaminated with pollutants can be better remediated.

  17. Thermodynamic investigation of the interaction between cyclodextrins and preservatives - Application and verification in a mathematical model to determine the needed preservative surplus in aqueous cyclodextrin formulations.

    PubMed

    Holm, René; Olesen, Niels Erik; Alexandersen, Signe Dalgaard; Dahlgaard, Birgitte N; Westh, Peter; Mu, Huiling

    2016-05-25

    Preservatives are inactivated when added to conserve aqueous cyclodextrin (CD) formulations due to complex formation between CDs and the preservative. To maintain the desired conservation effect the preservative needs to be added in apparent surplus to account for this inactivation. The purpose of the present work was to establish a mathematical model, which defines this surplus based upon knowledge of stability constants and the minimal concentration of preservation to inhibit bacterial growth. The stability constants of benzoic acid, methyl- and propyl-paraben with different frequently used βCDs were determined by isothermal titration calorimetry. Based upon this knowledge mathematical models were constructed to account for the equilibrium systems and to calculate the required concentration of the preservations, which was evaluated experimentally based upon the USP/Ph. Eur./JP monograph. The mathematical calculations were able to predict the needed concentration of preservation in the presence of CDs; it clearly demonstrated the usefulness of including all underlying chemical equilibria in a mathematical model, such that the formulation design can be based on quantitative arguments. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. Instrument Landing System scattering

    DOT National Transportation Integrated Search

    1972-12-01

    The construction of a mathematical model of the Instrument Landing System (ILS) multipath problem has been undertaken. This report presents the theoretical basis for such a model, and newly achieved developments in ILS model construction.

  19. Modeling of Pressure Drop During Refrigerant Condensation in Pipe Minichannels

    NASA Astrophysics Data System (ADS)

    Sikora, Małgorzata; Bohdal, Tadeusz

    2017-12-01

    Investigations of refrigerant condensation in pipe minichannels are very challenging and complicated issue. Due to the multitude of influences very important is mathematical and computer modeling. Its allows for performing calculations for many different refrigerants under different flow conditions. A large number of experimental results published in the literature allows for experimental verification of correctness of the models. In this work is presented a mathematical model for calculation of flow resistance during condensation of refrigerants in the pipe minichannel. The model was developed in environment based on conservation equations. The results of calculations were verified by authors own experimental investigations results.

  20. Mathematical modeling and computer simulation of isoelectric focusing with electrochemically defined ampholytes

    NASA Technical Reports Server (NTRS)

    Palusinski, O. A.; Allgyer, T. T.; Mosher, R. A.; Bier, M.; Saville, D. A.

    1981-01-01

    A mathematical model of isoelectric focusing at the steady state has been developed for an M-component system of electrochemically defined ampholytes. The model is formulated from fundamental principles describing the components' chemical equilibria, mass transfer resulting from diffusion and electromigration, and electroneutrality. The model consists of ordinary differential equations coupled with a system of algebraic equations. The model is implemented on a digital computer using FORTRAN-based simulation software. Computer simulation data are presented for several two-component systems showing the effects of varying the isoelectric points and dissociation constants of the constituents.

  1. System analysis of a piston steam engine employing the uniflow principle, a study in optimized performance

    NASA Technical Reports Server (NTRS)

    Peoples, J. A.

    1975-01-01

    Results are reported which were obtained from a mathematical model of a generalized piston steam engine configuration employing the uniflow principal. The model accounted for the effects of clearance volume, compression work, and release volume. A simple solution is presented which characterizes optimum performance of the steam engine, based on miles per gallon. Development of the mathematical model is presented. The relationship between efficiency and miles per gallon is developed. An approach to steam car analysis and design is presented which has purpose rather than lucky hopefulness. A practical engine design is proposed which correlates to the definition of the type engine used. This engine integrates several system components into the engine structure. All conclusions relate to the classical Rankine Cycle.

  2. Modelling Plane Geometry: the connection between Geometrical Visualization and Algebraic Demonstration

    NASA Astrophysics Data System (ADS)

    Pereira, L. R.; Jardim, D. F.; da Silva, J. M.

    2017-12-01

    The teaching and learning of Mathematics contents have been challenging along the history of the education, both for the teacher, in his dedicated task of teaching, as for the student, in his arduous and constant task of learning. One of the topics that are most discussed in these contents is the difference between the concepts of proof and demonstration. This work presents an interesting discussion about such concepts considering the use of the mathematical modeling approach for teaching, applied to some examples developed in the classroom with a group of students enrolled in the discipline of Geometry of the Mathematics curse of UFVJM.

  3. Development of the mathematical model for design and verification of acoustic modal analysis methods

    NASA Astrophysics Data System (ADS)

    Siner, Alexander; Startseva, Maria

    2016-10-01

    To reduce the turbofan noise it is necessary to develop methods for the analysis of the sound field generated by the blade machinery called modal analysis. Because modal analysis methods are very difficult and their testing on the full scale measurements are very expensive and tedious it is necessary to construct some mathematical models allowing to test modal analysis algorithms fast and cheap. At this work the model allowing to set single modes at the channel and to analyze generated sound field is presented. Modal analysis of the sound generated by the ring array of point sound sources is made. Comparison of experimental and numerical modal analysis results is presented at this work.

  4. A discrete in continuous mathematical model of cardiac progenitor cells formation and growth as spheroid clusters (Cardiospheres).

    PubMed

    Di Costanzo, Ezio; Giacomello, Alessandro; Messina, Elisa; Natalini, Roberto; Pontrelli, Giuseppe; Rossi, Fabrizio; Smits, Robert; Twarogowska, Monika

    2018-03-14

    We propose a discrete in continuous mathematical model describing the in vitro growth process of biophsy-derived mammalian cardiac progenitor cells growing as clusters in the form of spheres (Cardiospheres). The approach is hybrid: discrete at cellular scale and continuous at molecular level. In the present model, cells are subject to the self-organizing collective dynamics mechanism and, additionally, they can proliferate and differentiate, also depending on stochastic processes. The two latter processes are triggered and regulated by chemical signals present in the environment. Numerical simulations show the structure and the development of the clustered progenitors and are in a good agreement with the results obtained from in vitro experiments.

  5. Current advances in mathematical modeling of anti-cancer drug penetration into tumor tissues.

    PubMed

    Kim, Munju; Gillies, Robert J; Rejniak, Katarzyna A

    2013-11-18

    Delivery of anti-cancer drugs to tumor tissues, including their interstitial transport and cellular uptake, is a complex process involving various biochemical, mechanical, and biophysical factors. Mathematical modeling provides a means through which to understand this complexity better, as well as to examine interactions between contributing components in a systematic way via computational simulations and quantitative analyses. In this review, we present the current state of mathematical modeling approaches that address phenomena related to drug delivery. We describe how various types of models were used to predict spatio-temporal distributions of drugs within the tumor tissue, to simulate different ways to overcome barriers to drug transport, or to optimize treatment schedules. Finally, we discuss how integration of mathematical modeling with experimental or clinical data can provide better tools to understand the drug delivery process, in particular to examine the specific tissue- or compound-related factors that limit drug penetration through tumors. Such tools will be important in designing new chemotherapy targets and optimal treatment strategies, as well as in developing non-invasive diagnosis to monitor treatment response and detect tumor recurrence.

  6. Mathematical modeling and numerical simulation of the mitotic spindle orientation system.

    PubMed

    Ibrahim, Bashar

    2018-05-21

    The mitotic spindle orientation and position is crucial for the fidelity of chromosome segregation during asymmetric cell division to generate daughter cells with different sizes or fates. This mechanism is best understood in the budding yeast Saccharomyces cerevisiae, named the spindle position checkpoint (SPOC). The SPOC inhibits cells from exiting mitosis until the mitotic spindle is properly oriented along the mother-daughter polarity axis. Despite many experimental studies, the mechanisms underlying SPOC regulation remains elusive and unexplored theoretically. Here, a minimal mathematical is developed to describe SPOC activation and silencing having autocatalytic feedback-loop. Numerical simulations of the nonlinear ordinary differential equations (ODEs) model accurately reproduce the phenotype of SPOC mechanism. Bifurcation analysis of the nonlinear ODEs reveals the orientation dependency on spindle pole bodies, and how this dependence is altered by parameter values. These results provide for systems understanding on the molecular organization of spindle orientation system via mathematical modeling. The presented mathematical model is easy to understand and, within the above mentioned context, can be used as a base for further development of quantitative models in asymmetric cell-division. Copyright © 2018. Published by Elsevier Inc.

  7. Development of a mathematical model for the growth associated Polyhydroxybutyrate fermentation by Azohydromonas australica and its use for the design of fed-batch cultivation strategies.

    PubMed

    Gahlawat, Geeta; Srivastava, Ashok K

    2013-06-01

    In the present investigation, batch cultivation of Azohydromonas australica DSM 1124 was carried out in a bioreactor for growth associated PHB production. The observed batch PHB production kinetics data was then used for the development of a mathematical model which adequately described the substrate limitation and inhibition during the cultivation. The statistical validity test demonstrated that the proposed mathematical model predictions were significant at 99% confidence level. The model was thereafter extrapolated to fed-batch to identify various nutrients feeding regimes during the bioreactor cultivation to improve the PHB accumulation. The distinct capability of the mathematical model to predict highly dynamic fed-batch cultivation strategies was demonstrated by experimental implementation of two fed-batch cultivation strategies. A significantly high PHB concentration of 22.65 g/L & an overall PHB content of 76% was achieved during constant feed rate fed-batch cultivation which is the highest PHB content reported so far using A. australica. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Review Of Applied Mathematical Models For Describing The Behaviour Of Aqueous Humor In Eye Structures

    NASA Astrophysics Data System (ADS)

    Dzierka, M.; Jurczak, P.

    2015-12-01

    In the paper, currently used methods for modeling the flow of the aqueous humor through eye structures are presented. Then a computational model based on rheological models of Newtonian and non-Newtonian fluids is proposed. The proposed model may be used for modeling the flow of the aqueous humor through the trabecular meshwork. The trabecular meshwork is modeled as an array of rectilinear parallel capillary tubes. The flow of Newtonian and non-Newtonian fluids is considered. As a results of discussion mathematical equations of permeability of porous media and velocity of fluid flow through porous media have been received.

  9. PREDICTING ATTENUATION OF VIRUSES DURING PERCOLATION IN SOILS: 2. USER'S GUIDE TO THE VIRULO 1.0 COMPUTER MODEL

    EPA Science Inventory

    In the EPA document Predicting Attenuation of Viruses During Percolation in Soils 1. Probabilistic Model the conceptual, theoretical, and mathematical foundations for a predictive screening model were presented. In this current volume we present a User's Guide for the computer mo...

  10. Mathematical Model Taking into Account Nonlocal Effects of Plasmonic Structures on the Basis of the Discrete Source Method

    NASA Astrophysics Data System (ADS)

    Eremin, Yu. A.; Sveshnikov, A. G.

    2018-04-01

    The discrete source method is used to develop and implement a mathematical model for solving the problem of scattering electromagnetic waves by a three-dimensional plasmonic scatterer with nonlocal effects taken into account. Numerical results are presented whereby the features of the scattering properties of plasmonic particles with allowance for nonlocal effects are demonstrated depending on the direction and polarization of the incident wave.

  11. Mathematic models for a ray tracing method and its applications in wireless optical communications.

    PubMed

    Zhang, Minglun; Zhang, Yangan; Yuan, Xueguang; Zhang, Jinnan

    2010-08-16

    This paper presents a new ray tracing method, which contains a whole set of mathematic models, and its validity is verified by simulations. In addition, both theoretical analysis and simulation results show that the computational complexity of the method is much lower than that of previous ones. Therefore, the method can be used to rapidly calculate the impulse response of wireless optical channels for complicated systems.

  12. Mathematical Models of Blast-Induced TBI: Current Status, Challenges, and Prospects

    PubMed Central

    Gupta, Raj K.; Przekwas, Andrzej

    2013-01-01

    Blast-induced traumatic brain injury (TBI) has become a signature wound of recent military activities and is the leading cause of death and long-term disability among U.S. soldiers. The current limited understanding of brain injury mechanisms impedes the development of protection, diagnostic, and treatment strategies. We believe mathematical models of blast wave brain injury biomechanics and neurobiology, complemented with in vitro and in vivo experimental studies, will enable a better understanding of injury mechanisms and accelerate the development of both protective and treatment strategies. The goal of this paper is to review the current state of the art in mathematical and computational modeling of blast-induced TBI, identify research gaps, and recommend future developments. A brief overview of blast wave physics, injury biomechanics, and the neurobiology of brain injury is used as a foundation for a more detailed discussion of multiscale mathematical models of primary biomechanics and secondary injury and repair mechanisms. The paper also presents a discussion of model development strategies, experimental approaches to generate benchmark data for model validation, and potential applications of the model for prevention and protection against blast wave TBI. PMID:23755039

  13. DMPy: a Python package for automated mathematical model construction of large-scale metabolic systems.

    PubMed

    Smith, Robert W; van Rosmalen, Rik P; Martins Dos Santos, Vitor A P; Fleck, Christian

    2018-06-19

    Models of metabolism are often used in biotechnology and pharmaceutical research to identify drug targets or increase the direct production of valuable compounds. Due to the complexity of large metabolic systems, a number of conclusions have been drawn using mathematical methods with simplifying assumptions. For example, constraint-based models describe changes of internal concentrations that occur much quicker than alterations in cell physiology. Thus, metabolite concentrations and reaction fluxes are fixed to constant values. This greatly reduces the mathematical complexity, while providing a reasonably good description of the system in steady state. However, without a large number of constraints, many different flux sets can describe the optimal model and we obtain no information on how metabolite levels dynamically change. Thus, to accurately determine what is taking place within the cell, finer quality data and more detailed models need to be constructed. In this paper we present a computational framework, DMPy, that uses a network scheme as input to automatically search for kinetic rates and produce a mathematical model that describes temporal changes of metabolite fluxes. The parameter search utilises several online databases to find measured reaction parameters. From this, we take advantage of previous modelling efforts, such as Parameter Balancing, to produce an initial mathematical model of a metabolic pathway. We analyse the effect of parameter uncertainty on model dynamics and test how recent flux-based model reduction techniques alter system properties. To our knowledge this is the first time such analysis has been performed on large models of metabolism. Our results highlight that good estimates of at least 80% of the reaction rates are required to accurately model metabolic systems. Furthermore, reducing the size of the model by grouping reactions together based on fluxes alters the resulting system dynamics. The presented pipeline automates the modelling process for large metabolic networks. From this, users can simulate their pathway of interest and obtain a better understanding of how altering conditions influences cellular dynamics. By testing the effects of different parameterisations we are also able to provide suggestions to help construct more accurate models of complete metabolic systems in the future.

  14. Mathematical models of ABE fermentation: review and analysis.

    PubMed

    Mayank, Rahul; Ranjan, Amrita; Moholkar, Vijayanand S

    2013-12-01

    Among different liquid biofuels that have emerged in the recent past, biobutanol produced via fermentation processes is of special interest due to very similar properties to that of gasoline. For an effective design, scale-up, and optimization of the acetone-butanol-ethanol (ABE) fermentation process, it is necessary to have insight into the micro- and macro-mechanisms of the process. The mathematical models for ABE fermentation are efficient tools for this purpose, which have evolved from simple stoichiometric fermentation equations in the 1980s to the recent sophisticated and elaborate kinetic models based on metabolic pathways. In this article, we have reviewed the literature published in the area of mathematical modeling of the ABE fermentation. We have tried to present an analysis of these models in terms of their potency in describing the overall physiology of the process, design features, mode of operation along with comparison and validation with experimental results. In addition, we have also highlighted important facets of these models such as metabolic pathways, basic kinetics of different metabolites, biomass growth, inhibition modeling and other additional features such as cell retention and immobilized cultures. Our review also covers the mathematical modeling of the downstream processing of ABE fermentation, i.e. recovery and purification of solvents through flash distillation, liquid-liquid extraction, and pervaporation. We believe that this review will be a useful source of information and analysis on mathematical models for ABE fermentation for both the appropriate scientific and engineering communities.

  15. A mathematical model for the interactive behavior of sulfate-reducing bacteria and methanogens during anaerobic digestion.

    PubMed

    Ahammad, S Ziauddin; Gomes, James; Sreekrishnan, T R

    2011-09-01

    Anaerobic degradation of waste involves different classes of microorganisms, and there are different types of interactions among them for substrates, terminal electron acceptors, and so on. A mathematical model is developed based on the mass balance of different substrates, products, and microbes present in the system to study the interaction between methanogens and sulfate-reducing bacteria (SRB). The performance of major microbial consortia present in the system, such as propionate-utilizing acetogens, butyrate-utilizing acetogens, acetoclastic methanogens, hydrogen-utilizing methanogens, and SRB were considered and analyzed in the model. Different substrates consumed and products formed during the process also were considered in the model. The experimental observations and model predictions showed very good prediction capabilities of the model. Model prediction was validated statistically. It was observed that the model-predicted values matched the experimental data very closely, with an average error of 3.9%.

  16. Hispanic students' mathematics achievement in the context of their high school types as STEM and non-STEM schools

    NASA Astrophysics Data System (ADS)

    Bicer, Ali; Capraro, Robert M.; Capraro, Mary M.

    2018-07-01

    The purpose of this paper is to demonstrate Hispanic students' mathematics achievement growth rate in Inclusive science, technology, engineering, and mathematics (STEM) high schools compared to Hispanic students' mathematics achievement growth rate in traditional public schools. Twenty-eight schools, 14 of which were Texas STEM (T-STEM) academies and 14 of which were matched non-STEM schools, were included in this study. A hierarchical linear modelling method was conducted. The result of the present study revealed that there was no difference in Hispanic students' mathematics achievement growth rate in T-STEM academies compared to Hispanic students' mathematics achievement growth rate in comparison schools. However, in terms of gender, the results indicated that female Hispanic students in T-STEM academies outperformed female Hispanic students in comparison schools in their mathematics growth rate.

  17. Modeling Newspaper Advertising

    ERIC Educational Resources Information Center

    Harper, Joseph; And Others

    1978-01-01

    Presents a mathematical model for simulating a newspaper financial system. Includes the effects of advertising and circulation for predicting advertising linage as a function of population, income, and advertising rate. (RL)

  18. Evaluation of losses in transmission of machinery for development of mineral deposits in conditions of variable load

    NASA Astrophysics Data System (ADS)

    Zvonarev, I. E.; Ivanov, S. L.

    2017-10-01

    The influence of individual elements of machines transmissions on the operation of the whole system is shown. The approach of determining the resource of operation of systems elements based on the energy theory is presented. The formulas for determining the total energy resource of the reducer are given. The influence of individual elements of the system on each other is indicated. The principle of researching the system by the method of equivalent circuits is substantiated. The weakest places of transmission (gears, bearing supports and shafts) are determined. A mathematical model of a mechanical transmission was developed. To test the adequacy of the mathematical model, the stand for obtaining experimental data was designed. The description of the stand and the principle of its operation are given. Experimental data are presented. A comparative analysis of modeling and experimental data is carried out and the adequacy of the developed mathematical model is proved. The principle of determining the resource of the system as a whole for the element with the minimal resource of work is suggested.

  19. Two-dimensional coupled mathematical modeling of fluvial processes with intense sediment transport and rapid bed evolution

    NASA Astrophysics Data System (ADS)

    Yue, Zhiyuan; Cao, Zhixian; Li, Xin; Che, Tao

    2008-09-01

    Alluvial rivers may experience intense sediment transport and rapid bed evolution under a high flow regime, for which traditional decoupled mathematical river models based on simplified conservation equations are not applicable. A two-dimensional coupled mathematical model is presented, which is generally applicable to the fluvial processes with either intense or weak sediment transport. The governing equations of the model comprise the complete shallow water hydrodynamic equations closed with Manning roughness for boundary resistance and empirical relationships for sediment exchange with the erodible bed. The second-order Total-Variation-Diminishing version of the Weighted-Average-Flux method, along with the HLLC approximate Riemann Solver, is adapted to solve the governing equations, which can properly resolve shock waves and contact discontinuities. The model is applied to the pilot study of the flooding due to a sudden outburst of a real glacial-lake.

  20. Nonlinear-programming mathematical modeling of coal blending for power plant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tang Longhua; Zhou Junhu; Yao Qiang

    At present most of the blending works are guided by experience or linear-programming (LP) which can not reflect the coal complicated characteristics properly. Experimental and theoretical research work shows that most of the coal blend properties can not always be measured as a linear function of the properties of the individual coals in the blend. The authors introduced nonlinear functions or processes (including neural network and fuzzy mathematics), established on the experiments directed by the authors and other researchers, to quantitatively describe the complex coal blend parameters. Finally nonlinear-programming (NLP) mathematical modeling of coal blend is introduced and utilized inmore » the Hangzhou Coal Blending Center. Predictions based on the new method resulted in different results from the ones based on LP modeling. The authors concludes that it is very important to introduce NLP modeling, instead of NL modeling, into the work of coal blending.« less

  1. Simulating the evolution of non-point source pollutants in a shallow water environment.

    PubMed

    Yan, Min; Kahawita, Rene

    2007-03-01

    Non-point source pollution originating from surface applied chemicals in either liquid or solid form as part of agricultural activities, appears in the surface runoff caused by rainfall. The infiltration and transport of these pollutants has a significant impact on subsurface and riverine water quality. The present paper describes the development of a unified 2-D mathematical model incorporating individual models for infiltration, adsorption, solubility rate, advection and diffusion, which significantly improve the current practice on mathematical modeling of pollutant evolution in shallow water. The governing equations have been solved numerically using cubic spline integration. Experiments were conducted at the Hydrodynamics Laboratory of the Ecole Polytechnique de Montreal to validate the mathematical model. Good correspondence between the computed results and experimental data has been obtained. The model may be used to predict the ultimate fate of surface applied chemicals by evaluating the proportions that are dissolved, infiltrated into the subsurface or are washed off.

  2. Mathematical model for adaptive control system of ASEA robot at Kennedy Space Center

    NASA Technical Reports Server (NTRS)

    Zia, Omar

    1989-01-01

    The dynamic properties and the mathematical model for the adaptive control of the robotic system presently under investigation at Robotic Application and Development Laboratory at Kennedy Space Center are discussed. NASA is currently investigating the use of robotic manipulators for mating and demating of fuel lines to the Space Shuttle Vehicle prior to launch. The Robotic system used as a testbed for this purpose is an ASEA IRB-90 industrial robot with adaptive control capabilities. The system was tested and it's performance with respect to stability was improved by using an analogue force controller. The objective of this research project is to determine the mathematical model of the system operating under force feedback control with varying dynamic internal perturbation in order to provide continuous stable operation under variable load conditions. A series of lumped parameter models are developed. The models include some effects of robot structural dynamics, sensor compliance, and workpiece dynamics.

  3. Mathematical modeling and spectrum analysis of the physiological patello-femoral pulse train produced by slow knee movement.

    PubMed

    Zhang, Y T; Frank, C B; Rangayyan, R M; Bell, G D

    1992-09-01

    Analysis of vibration signals emitted by the knee joint has the potential for the development of a noninvasive procedure for the diagnosis and monitoring of knee pathology. In order to obtain as much information as possible from the power density spectrum of the knee vibration signal, it is necessary to identify the physiological factors (or physiologically relevant parameters) that shape the spectrum. This paper presents a mathematical model for knee vibration signals, in particular the physiological patello-femoral pulse (PFP) train produced by slow knee movement. It demonstrates through the mathematical model that the repetition rate of the physiological PFP train introduces repeated peaks in the power spectrum, and that it affects the spectrum mainly at low frequencies. The theoretical results also show that the spectral peaks at multiples of the PFP repetition rate become more evident when the variance of the interpulse interval (IPI) is small, and that these spectral peaks shift toward higher frequencies with increasing PFP repetition rates. To evaluate the mathematical model, a simulation algorithm was developed, which generates PFP signals with adjustable repetition rate and IPI variance. Signals generated by simulation were seen to possess representative spectral characteristics typically observed in physiological PFP signals. This simulation procedure allows an interactive examination of several factors which affect the PFP train spectrum. Finally, in vivo measurements of physiological PFP signals of normal volunteers are presented. Results of simulations and analysis of signals recorded from human subjects support the mathematical model's prediction that the IPI statistics play a very significant role in determining the low-end power spectrum of the physiological PFP signal.(ABSTRACT TRUNCATED AT 250 WORDS)

  4. Mathematical modelling and quantitative methods.

    PubMed

    Edler, L; Poirier, K; Dourson, M; Kleiner, J; Mileson, B; Nordmann, H; Renwick, A; Slob, W; Walton, K; Würtzen, G

    2002-01-01

    The present review reports on the mathematical methods and statistical techniques presently available for hazard characterisation. The state of the art of mathematical modelling and quantitative methods used currently for regulatory decision-making in Europe and additional potential methods for risk assessment of chemicals in food and diet are described. Existing practices of JECFA, FDA, EPA, etc., are examined for their similarities and differences. A framework is established for the development of new and improved quantitative methodologies. Areas for refinement, improvement and increase of efficiency of each method are identified in a gap analysis. Based on this critical evaluation, needs for future research are defined. It is concluded from our work that mathematical modelling of the dose-response relationship would improve the risk assessment process. An adequate characterisation of the dose-response relationship by mathematical modelling clearly requires the use of a sufficient number of dose groups to achieve a range of different response levels. This need not necessarily lead to an increase in the total number of animals in the study if an appropriate design is used. Chemical-specific data relating to the mode or mechanism of action and/or the toxicokinetics of the chemical should be used for dose-response characterisation whenever possible. It is concluded that a single method of hazard characterisation would not be suitable for all kinds of risk assessments, and that a range of different approaches is necessary so that the method used is the most appropriate for the data available and for the risk characterisation issue. Future refinements to dose-response characterisation should incorporate more clearly the extent of uncertainty and variability in the resulting output.

  5. Method of performing computational aeroelastic analyses

    NASA Technical Reports Server (NTRS)

    Silva, Walter A. (Inventor)

    2011-01-01

    Computational aeroelastic analyses typically use a mathematical model for the structural modes of a flexible structure and a nonlinear aerodynamic model that can generate a plurality of unsteady aerodynamic responses based on the structural modes for conditions defining an aerodynamic condition of the flexible structure. In the present invention, a linear state-space model is generated using a single execution of the nonlinear aerodynamic model for all of the structural modes where a family of orthogonal functions is used as the inputs. Then, static and dynamic aeroelastic solutions are generated using computational interaction between the mathematical model and the linear state-space model for a plurality of periodic points in time.

  6. Vamos a Jugar Counters! Learning Mathematics through Funds of Knowledge, Play, and the Third Space

    ERIC Educational Resources Information Center

    Razfar, Aria

    2012-01-01

    Drawing on Cultural Historical Activity Theory (CHAT), funds of knowledge, and third space, this article presents a model for practitioners and researchers to think about how Latina/o, bilingual children develop explicit mathematics strategies through multilingual and multigenerational interactions. Using data collected through fieldwork in an…

  7. Information Technology, Mathematics Achievement and Educational Equity in Developed Economies

    ERIC Educational Resources Information Center

    Tan, Cheng Yong; Hew, Khe Foon

    2017-01-01

    The present study examined how access to home and school IT resources impacted student mathematics achievement. Data comprised 144,395 secondary school students from 7,308 schools in 22 developed economies who participated in the Programme for International Student Assessment (PISA) 2012. Results of hierarchical linear modelling showed that after…

  8. Common Grounds for Modelling Mathematics in Educational Software

    ERIC Educational Resources Information Center

    Neuper, Walther

    2010-01-01

    Two kinds of software, CAS and DGS, are starting to work towards mutual integration. This paper envisages common grounds for such integration based on principles of computer theorem proving (CTP). Presently, the CTP community seems to lack awareness as to which of their products' features might serve mathematics education from high-school to…

  9. The Development from Effortful to Automatic Processing in Mathematical Cognition.

    ERIC Educational Resources Information Center

    Kaye, Daniel B.; And Others

    This investigation capitalizes upon the information processing models that depend upon measurement of latency of response to a mathematical problem and the decomposition of reaction time (RT). Simple two term addition problems were presented with possible solutions for true-false verification, and accuracy and RT to response were recorded. Total…

  10. A Constructivist Computational Platform to Support Mathematics Education in Elementary School

    ERIC Educational Resources Information Center

    Garcia, I.; Pacheco, C.

    2013-01-01

    Many courses for elementary school are based upon teacher presentation and explanation of basic topics, rather than allowing students to develop their own knowledge. This traditional model may turn elementary-level lessons into an extremely theoretical, boring and non-effective process. In this context, research in mathematics elementary education…

  11. On the Ability To Infer Deficiency in Mathematics From Performance in Physics Using Hierarchies

    ERIC Educational Resources Information Center

    Riban, David M.

    1971-01-01

    Presents the procedures, results, and conclusions of a study designed to see if mathematical deficiencies can be inferred from PSSC students' performance by using a hierarchical model of requisite skills. Assuming inferences were possible, remediation was given. No effect due to remediation was observed but analysis indicated incidental learning…

  12. Mathematical model of a DIC position sensing system within an optical trap

    NASA Astrophysics Data System (ADS)

    Wulff, Kurt D.; Cole, Daniel G.; Clark, Robert L.

    2005-08-01

    The quantitative study of displacements and forces of motor proteins and processes that occur at the microscopic level and below require a high level of sensitivity. For optical traps, two techniques for position sensing have been accepted and used quite extensively: quadrant photodiodes and an interferometric position sensing technique based on DIC imaging. While quadrant photodiodes have been studied in depth and mathematically characterized, a mathematical characterization of the interferometric position sensor has not been presented to the authors' knowledge. The interferometric position sensing method works off of the DIC imaging capabilities of a microscope. Circularly polarized light is sent into the microscope and the Wollaston prism used for DIC imaging splits the beam into its orthogonal components, displacing them by a set distance determined by the user. The distance between the axes of the beams is set so the beams overlap at the specimen plane and effectively share the trapped microsphere. A second prism then recombines the light beams and the exiting laser light's polarization is measured and related to position. In this paper we outline the mathematical characterization of a microsphere suspended in an optical trap using a DIC position sensing method. The sensitivity of this mathematical model is then compared to the QPD model. The mathematical model of a microsphere in an optical trap can serve as a calibration curve for an experimental setup.

  13. Mathematics for understanding disease.

    PubMed

    Bies, R R; Gastonguay, M R; Schwartz, S L

    2008-06-01

    The application of mathematical models to reflect the organization and activity of biological systems can be viewed as a continuum of purpose. The far left of the continuum is solely the prediction of biological parameter values, wherein an understanding of the underlying biological processes is irrelevant to the purpose. At the far right of the continuum are mathematical models, the purposes of which are a precise understanding of those biological processes. No models in present use fall at either end of the continuum. Without question, however, the emphasis in regards to purpose has been on prediction, e.g., clinical trial simulation and empirical disease progression modeling. Clearly the model that ultimately incorporates a universal understanding of biological organization will also precisely predict biological events, giving the continuum the logical form of a tautology. Currently that goal lies at an immeasurable distance. Nonetheless, the motive here is to urge movement in the direction of that goal. The distance traveled toward understanding naturally depends upon the nature of the scientific question posed with respect to comprehending and/or predicting a particular disease process. A move toward mathematical models implies a move away from static empirical modeling and toward models that focus on systems biology, wherein modeling entails the systematic study of the complex pattern of organization inherent in biological systems.

  14. Regulatory T cell effects in antitumor laser immunotherapy: a mathematical model and analysis

    NASA Astrophysics Data System (ADS)

    Dawkins, Bryan A.; Laverty, Sean M.

    2016-03-01

    Regulatory T cells (Tregs) have tremendous influence on treatment outcomes in patients receiving immunotherapy for cancerous tumors. We present a mathematical model incorporating the primary cellular and molecular components of antitumor laser immunotherapy. We explicitly model developmental classes of dendritic cells (DCs), cytotoxic T cells (CTLs), primary and metastatic tumor cells, and tumor antigen. Regulatory T cells have been shown to kill antigen presenting cells, to influence dendritic cell maturation and migration, to kill activated killer CTLs in the tumor microenvironment, and to influence CTL proliferation. Since Tregs affect explicitly modeled cells, but we do not explicitly model dynamics of Treg themselves, we use model parameters to analyze effects of Treg immunosuppressive activity. We will outline a systematic method for assigning clinical outcomes to model simulations and use this condition to associate simulated patient treatment outcome with Treg activity.

  15. Stochastic Modeling and Generation of Partially Polarized or Partially Coherent Electromagnetic Waves

    NASA Technical Reports Server (NTRS)

    Davis, Brynmor; Kim, Edward; Piepmeier, Jeffrey; Hildebrand, Peter H. (Technical Monitor)

    2001-01-01

    Many new Earth remote-sensing instruments are embracing both the advantages and added complexity that result from interferometric or fully polarimetric operation. To increase instrument understanding and functionality a model of the signals these instruments measure is presented. A stochastic model is used as it recognizes the non-deterministic nature of any real-world measurements while also providing a tractable mathematical framework. A stationary, Gaussian-distributed model structure is proposed. Temporal and spectral correlation measures provide a statistical description of the physical properties of coherence and polarization-state. From this relationship the model is mathematically defined. The model is shown to be unique for any set of physical parameters. A method of realizing the model (necessary for applications such as synthetic calibration-signal generation) is given and computer simulation results are presented. The signals are constructed using the output of a multi-input multi-output linear filter system, driven with white noise.

  16. Mathematical modeling of the heat transfer during pyrolysis process used for end-of-life tires treatment

    NASA Astrophysics Data System (ADS)

    Zheleva, I.; Georgiev, I.; Filipova, M.; Menseidov, D.

    2017-10-01

    Mathematical modeling of the heat transfer during the pyrolysis process used for the treatment of the End-of-Lifetires (EOLT) is presented in this paper. The pyrolysis process is 3D and non-stationary and because of this it is very complicated for modeling and studying. To simplify the modeling here a hierarchy of 2D models for the temperature which describe the non-stationary heat transfer in such a pyrolysis station is created. An algorithm for solving the model equations, based on MATLAB software is developed. The results for the temperature for some characteristic periods of operation of pyrolysis station are presented and commented in the paper. The results from this modeling can be used in the real pyrolysis station for more precise displacement of measurement devices and for designing of automated management of the process.

  17. Statistical Mechanics of Disordered Systems - Series: Cambridge Series in Statistical and Probabilistic Mathematics (No. 18)

    NASA Astrophysics Data System (ADS)

    Bovier, Anton

    2006-06-01

    Our mathematical understanding of the statistical mechanics of disordered systems is going through a period of stunning progress. This self-contained book is a graduate-level introduction for mathematicians and for physicists interested in the mathematical foundations of the field, and can be used as a textbook for a two-semester course on mathematical statistical mechanics. It assumes only basic knowledge of classical physics and, on the mathematics side, a good working knowledge of graduate-level probability theory. The book starts with a concise introduction to statistical mechanics, proceeds to disordered lattice spin systems, and concludes with a presentation of the latest developments in the mathematical understanding of mean-field spin glass models. In particular, recent progress towards a rigorous understanding of the replica symmetry-breaking solutions of the Sherrington-Kirkpatrick spin glass models, due to Guerra, Aizenman-Sims-Starr and Talagrand, is reviewed in some detail. Comprehensive introduction to an active and fascinating area of research Clear exposition that builds to the state of the art in the mathematics of spin glasses Written by a well-known and active researcher in the field

  18. The Quark's Model and Confinement

    ERIC Educational Resources Information Center

    Novozhilov, Yuri V.

    1977-01-01

    Quarks are elementary particles considered to be components of the proton, the neutron, and others. This article presents the quark model as a mathematical concept. Also discussed are gluons and bag models. A bibliography is included. (MA)

  19. Modeling and control of flexible space platforms with articulated payloads

    NASA Technical Reports Server (NTRS)

    Graves, Philip C.; Joshi, Suresh M.

    1989-01-01

    The first steps in developing a methodology for spacecraft control-structure interaction (CSI) optimization are identification and classification of anticipated missions, and the development of tractable mathematical models in each mission class. A mathematical model of a generic large flexible space platform (LFSP) with multiple independently pointed rigid payloads is considered. The objective is not to develop a general purpose numerical simulation, but rather to develop an analytically tractable mathematical model of such composite systems. The equations of motion for a single payload case are derived, and are linearized about zero steady-state. The resulting model is then extended to include multiple rigid payloads, yielding the desired analytical form. The mathematical models developed clearly show the internal inertial/elastic couplings, and are therefore suitable for analytical and numerical studies. A simple decentralized control law is proposed for fine pointing the payloads and LFSP attitude control, and simulation results are presented for an example problem. The decentralized controller is shown to be adequate for the example problem chosen, but does not, in general, guarantee stability. A centralized dissipative controller is then proposed, requiring a symmetric form of the composite system equations. Such a controller guarantees robust closed loop stability despite unmodeled elastic dynamics and parameter uncertainties.

  20. Optimization of Thermal Object Nonlinear Control Systems by Energy Efficiency Criterion.

    NASA Astrophysics Data System (ADS)

    Velichkin, Vladimir A.; Zavyalov, Vladimir A.

    2018-03-01

    This article presents the results of thermal object functioning control analysis (heat exchanger, dryer, heat treatment chamber, etc.). The results were used to determine a mathematical model of the generalized thermal control object. The appropriate optimality criterion was chosen to make the control more energy-efficient. The mathematical programming task was formulated based on the chosen optimality criterion, control object mathematical model and technological constraints. The “maximum energy efficiency” criterion helped avoid solving a system of nonlinear differential equations and solve the formulated problem of mathematical programming in an analytical way. It should be noted that in the case under review the search for optimal control and optimal trajectory reduces to solving an algebraic system of equations. In addition, it is shown that the optimal trajectory does not depend on the dynamic characteristics of the control object.

  1. Numerical simulation of dynamics of brushless dc motors for aerospace and other applications. Volume 1: Model development and applications, part A

    NASA Technical Reports Server (NTRS)

    Demerdash, N. A. O.; Nehl, T. W.

    1979-01-01

    The development, fabrication and evaluation of a prototype electromechanical actuator (EMA) is discussed. Application of the EMA as a motor for control surfaces in aerospace flight is examined. A mathematical model of the EMA is developed for design optimization. Nonlinearities which complicate the mathematical model are discussed. The dynamics of the EMA from the underlying physical principles are determined and a discussion of similating the control logic by means of equivalent boolean expressions is presented.

  2. Numerical modeling of heat transfer in the fuel oil storage tank at thermal power plant

    NASA Astrophysics Data System (ADS)

    Kuznetsova, Svetlana A.

    2015-01-01

    Presents results of mathematical modeling of convection of a viscous incompressible fluid in a rectangular cavity with conducting walls of finite thickness in the presence of a local source of heat in the bottom of the field in terms of convective heat exchange with the environment. A mathematical model is formulated in terms of dimensionless variables "stream function - vorticity vector speed - temperature" in the Cartesian coordinate system. As the results show the distributions of hydrodynamic parameters and temperatures using different boundary conditions on the local heat source.

  3. Mathematical model describing the thyroids-pituitary axis with distributed time delays in hormone transportation

    NASA Astrophysics Data System (ADS)

    Neamţu, Mihaela; Stoian, Dana; Navolan, Dan Bogdan

    2014-12-01

    In the present paper we provide a mathematical model that describe the hypothalamus-pituitary-thyroid axis in autoimmune (Hashimoto's) thyroiditis. Since there is a spatial separation between thyroid and pituitary gland in the body, time is needed for transportation of thyrotropin and thyroxine between the glands. Thus, the distributed time delays are considered as both weak and Dirac kernels. The delayed model is analyzed regarding the stability and bifurcation behavior. The last part contains some numerical simulations to illustrate the effectiveness of our results and conclusions.

  4. Chancroid transmission dynamics: a mathematical modeling approach.

    PubMed

    Bhunu, C P; Mushayabasa, S

    2011-12-01

    Mathematical models have long been used to better understand disease transmission dynamics and how to effectively control them. Here, a chancroid infection model is presented and analyzed. The disease-free equilibrium is shown to be globally asymptotically stable when the reproduction number is less than unity. High levels of treatment are shown to reduce the reproduction number suggesting that treatment has the potential to control chancroid infections in any given community. This result is also supported by numerical simulations which show a decline in chancroid cases whenever the reproduction number is less than unity.

  5. Self-similar seismogenic structure of the crust: A review of the problem and a mathematical model

    NASA Astrophysics Data System (ADS)

    Stakhovsky, I. R.

    2007-12-01

    The paper presents a brief review of studies of the structural organization of a seismogenic medium showing that the crust of seismically active regions possesses a fractal structure. A new mathematical model of the self-similar seismogenic structure (SSS) of the crust generalizing the reviewed publications is proposed on the basis of the scaling correspondence between the fault, seismic, and seismic energy multifractal fields of the crust. Multifractal fields of other physical origin can also be incorporated in the SSS model.

  6. Mathematical and computational modelling of skin biophysics: a review

    PubMed Central

    2017-01-01

    The objective of this paper is to provide a review on some aspects of the mathematical and computational modelling of skin biophysics, with special focus on constitutive theories based on nonlinear continuum mechanics from elasticity, through anelasticity, including growth, to thermoelasticity. Microstructural and phenomenological approaches combining imaging techniques are also discussed. Finally, recent research applications on skin wrinkles will be presented to highlight the potential of physics-based modelling of skin in tackling global challenges such as ageing of the population and the associated skin degradation, diseases and traumas. PMID:28804267

  7. Mathematical and computational modelling of skin biophysics: a review

    NASA Astrophysics Data System (ADS)

    Limbert, Georges

    2017-07-01

    The objective of this paper is to provide a review on some aspects of the mathematical and computational modelling of skin biophysics, with special focus on constitutive theories based on nonlinear continuum mechanics from elasticity, through anelasticity, including growth, to thermoelasticity. Microstructural and phenomenological approaches combining imaging techniques are also discussed. Finally, recent research applications on skin wrinkles will be presented to highlight the potential of physics-based modelling of skin in tackling global challenges such as ageing of the population and the associated skin degradation, diseases and traumas.

  8. The mathematical modeling of rapid solidification processing. Ph.D. Thesis. Final Report

    NASA Technical Reports Server (NTRS)

    Gutierrez-Miravete, E.

    1986-01-01

    The detailed formulation of and the results obtained from a continuum mechanics-based mathematical model of the planar flow melt spinning (PFMS) rapid solidification system are presented and discussed. The numerical algorithm proposed is capable of computing the cooling and freezing rates as well as the fluid flow and capillary phenomena which take place inside the molten puddle formed in the PFMS process. The FORTRAN listings of some of the most useful computer programs and a collection of appendices describing the basic equations used for the modeling are included.

  9. A study of the dynamics of rotating space stations with elastically connected counterweight and attached flexible appendages. Volume 1: Theory

    NASA Technical Reports Server (NTRS)

    Austin, F.; Markowitz, J.; Goldenberg, S.; Zetkov, G. A.

    1973-01-01

    The formulation of a mathematical model for predicting the dynamic behavior of rotating flexible space station configurations was conducted. The overall objectives of the study were: (1) to develop the theoretical techniques for determining the behavior of a realistically modeled rotating space station, (2) to provide a versatile computer program for the numerical analysis, and (3) to present practical concepts for experimental verification of the analytical results. The mathematical model and its associated computer program are described.

  10. Milestones of mathematical model for business process management related to cost estimate documentation in petroleum industry

    NASA Astrophysics Data System (ADS)

    Khamidullin, R. I.

    2018-05-01

    The paper is devoted to milestones of the optimal mathematical model for a business process related to cost estimate documentation compiled during construction and reconstruction of oil and gas facilities. It describes the study and analysis of fundamental issues in petroleum industry, which are caused by economic instability and deterioration of a business strategy. Business process management is presented as business process modeling aimed at the improvement of the studied business process, namely main criteria of optimization and recommendations for the improvement of the above-mentioned business model.

  11. Propulsion system mathematical model for a lift/cruise fan V/STOL aircraft

    NASA Technical Reports Server (NTRS)

    Cole, G. L.; Sellers, J. F.; Tinling, B. E.

    1980-01-01

    A propulsion system mathematical model is documented that allows calculation of internal engine parameters during transient operation. A non-realtime digital computer simulation of the model is presented. It is used to investigate thrust response and modulation requirements as well as the impact of duty cycle on engine life and design criteria. Comparison of simulation results with steady-state cycle deck calculations showed good agreement. The model was developed for a specific 3-fan subsonic V/STOL aircraft application, but it can be adapted for use with any similar lift/cruise V/STOL configuration.

  12. On the Modeling of Vacuum Arc Remelting Process in Titanium Alloys

    NASA Astrophysics Data System (ADS)

    Patel, Ashish; Fiore, Daniel

    2016-07-01

    Mathematical modeling is routinely used in the process development and production of advanced aerospace alloys to gain greater insight into the effect of process parameters on final properties. This article describes the application of a 2-D mathematical VAR model presented at previous LMPC meetings. The impact of process parameters on melt pool geometry, solidification behavior, fluid-flow and chemistry in a Ti-6Al-4V ingot is discussed. Model predictions are validated against published data from a industrial size ingot, and results of a parametric study on particle dissolution are also discussed.

  13. Mathematization Competencies of Pre-Service Elementary Mathematics Teachers in the Mathematical Modelling Process

    ERIC Educational Resources Information Center

    Yilmaz, Suha; Tekin-Dede, Ayse

    2016-01-01

    Mathematization competency is considered in the field as the focus of modelling process. Considering the various definitions, the components of the mathematization competency are determined as identifying assumptions, identifying variables based on the assumptions and constructing mathematical model/s based on the relations among identified…

  14. Modeling Simple Telescope Optics in Secondary Mathematics Classrooms

    NASA Astrophysics Data System (ADS)

    Siegel, Lauren; Dickinson, G.; Hooper, E. J.; Daniels, M.

    2007-12-01

    This presentation describes the results of collaboration between instructors in the UTeach teacher preparation program at the University of Texas at Austin, and an astronomer teaching at the university as part of a National Science Foundation Astronomy and Astrophysics Postdoctoral Fellowship. The astronomer provided training to give pre-service teachers an authentic understanding of the principles of telescope optics. This made it possible for the preservice teachers to include real design constraints and optical properties into lessons developed as part of a collaborative field experience to teach astronomical telescope design and construction to high school Algebra II students. One result is a sequence of investigations designed to explore how and why the physical and mathematical properties of parabolic mirrors both enable and constrain our ability to build and use telescopes to focus light from distant objects. Various approaches, including generating and exploring computer models, traditional proofs, even making paper models, are all woven together into a coherent set of eleven investigations for use in mathematics and science classrooms. The presentation will include a description of the suite of investigations, as well as a discussion of the collaborative process which generated the work and resulted in an article submission to a preeminent teaching journal. Teaching Algebra and Geometry Concepts by Modeling Telescope Optics, 2008, Mathematics Teacher is currently in press. Many thanks to the University of Texas UTeach Program for sponsorship of this submission.

  15. Mathematical modeling based on ordinary differential equations: A promising approach to vaccinology

    PubMed Central

    Bonin, Carla Rezende Barbosa; Fernandes, Guilherme Cortes; dos Santos, Rodrigo Weber; Lobosco, Marcelo

    2017-01-01

    ABSTRACT New contributions that aim to accelerate the development or to improve the efficacy and safety of vaccines arise from many different areas of research and technology. One of these areas is computational science, which traditionally participates in the initial steps, such as the pre-screening of active substances that have the potential to become a vaccine antigen. In this work, we present another promising way to use computational science in vaccinology: mathematical and computational models of important cell and protein dynamics of the immune system. A system of Ordinary Differential Equations represents different immune system populations, such as B cells and T cells, antigen presenting cells and antibodies. In this way, it is possible to simulate, in silico, the immune response to vaccines under development or under study. Distinct scenarios can be simulated by varying parameters of the mathematical model. As a proof of concept, we developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature. The model is generic enough to represent the action of other diseases or vaccines in the human immune system, such as dengue and Zika virus. PMID:28027002

  16. Mathematical modeling based on ordinary differential equations: A promising approach to vaccinology.

    PubMed

    Bonin, Carla Rezende Barbosa; Fernandes, Guilherme Cortes; Dos Santos, Rodrigo Weber; Lobosco, Marcelo

    2017-02-01

    New contributions that aim to accelerate the development or to improve the efficacy and safety of vaccines arise from many different areas of research and technology. One of these areas is computational science, which traditionally participates in the initial steps, such as the pre-screening of active substances that have the potential to become a vaccine antigen. In this work, we present another promising way to use computational science in vaccinology: mathematical and computational models of important cell and protein dynamics of the immune system. A system of Ordinary Differential Equations represents different immune system populations, such as B cells and T cells, antigen presenting cells and antibodies. In this way, it is possible to simulate, in silico, the immune response to vaccines under development or under study. Distinct scenarios can be simulated by varying parameters of the mathematical model. As a proof of concept, we developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature. The model is generic enough to represent the action of other diseases or vaccines in the human immune system, such as dengue and Zika virus.

  17. The modeling of reactive solute transport with sorption to mobile and immobile sorbents 1. Experimental evidence and model development

    NASA Astrophysics Data System (ADS)

    Knabner, P.; Totsche, K. U.; Kögel-Knabner, I.

    Modeling carrier-influenced transport needs to take into account the reactivity of the carrier itself. This paper presents a mathematical model of reactive solute transport with sorption to mobile and immobile sorbents. The mobile sorbent is also considered to be reactive. To justify the assumptions and generality of our modeling approach, experimental findings are reviewed and analyzed. A transformation of the model in terms of total concentrations of solute and mobile sorbents is presented which simplifies the mathematical formulations. Breakthrough data on dissolved organic carbon are presented to exemplify the need to take into account the reactivity of the mobile sorbent. Data on hexachlorobiphenyl and cadmium are presented to demonstrate carrier-introduced increased mobility, whereas data on anthracene and pyrene are presented to demonstrate carrier-introduced reduced mobility. The experimental conditions leading to the different findings are pointed out. The sorption processes considered in the model are both equilibrium and nonequilibrium processes, allowing for different sorption sites and nonlinear isotherms and rate functions. Effective isotherms, which describe the sorption to the immobile sorbent in the presence of a mobile sorbent and rate functions, are introduced and their properties are discussed.

  18. Tapered Screened Channel PMD for Cryogenic Liquids

    NASA Astrophysics Data System (ADS)

    Dodge, Franklin T.; Green, Steve T.; Walter, David B.

    2004-02-01

    If a conventional spacecraft propellant management device (PMD) of the screened channel type were employed with a cryogenic liquid, vapor bubbles generated within the channel by heat transfer could ``dry out'' the channel screens and thereby cause the channels to admit large amounts of vapor from the tank into the liquid outflow. This paper describes a new tapered channel design that passively `pumps' bubbles away from the outlet port and vents them into the tank. A predictive mathematical model of the operating principle is presented and discussed. Scale-model laboratory tests were conducted and the mathematical model agreed well with the measured rates of bubble transport velocity. Finally, an example of the use of the predictive model for a realistic spacecraft application is presented. The model predicts that bubble clearing rates are acceptable even in tanks up to 2 m in length.

  19. Mathematical modeling of systemic factors determining the risk of deterioration of drinking water supply and development of allergic diseases of population

    NASA Astrophysics Data System (ADS)

    Bespalov, Yurii G.; Nosov, Konstantin V.; Vysotska, Olena V.; Porvan, Andrii P.; Omiotek, Zbigniew; Burlibay, Aron; Assembay, Azat; Szatkowska, Małgorzata

    2017-08-01

    This study aims at mathematical modeling of systemic factors threatening the sanitary and hygienic state of sources of water supply. It is well-known, that this state affects health of population consuming water from different water sources (lakes, reservoirs, rivers). In particular, water quality problem may cause allergic reactions that are the important problem of health care. In the paper, the authors present the mathematical model, that enables on the basis of observations of a natural system to predict the system's behavior and determine the risks related to deterioration of drinking water resources. As a case study, we uses supply of drinking water from Lake Sevan, but the approach developed in the study can be applied to wide area of adjacent problems.

  20. Pest control through viral disease: mathematical modeling and analysis.

    PubMed

    Bhattacharyya, S; Bhattacharya, D K

    2006-01-07

    This paper deals with the mathematical modeling of pest management under viral infection (i.e. using viral pesticide) and analysis of its essential mathematical features. As the viral infection induces host lysis which releases more virus into the environment, on the average 'kappa' viruses per host, kappain(1,infinity), the 'virus replication parameter' is chosen as the main parameter on which the dynamics of the infection depends. We prove that there exists a threshold value kappa(0) beyond which the endemic equilibrium bifurcates from the free disease one. Still for increasing kappa values, the endemic equilibrium bifurcates towards a periodic solution. We further analyse the orbital stability of the periodic orbits arising from bifurcation by applying Poor's condition. A concluding discussion with numerical simulation of the model is then presented.

  1. [Mathematical modeling: an essential tool for the study of therapeutic targeting in solid tumors].

    PubMed

    Saidak, Zuzana; Giacobbi, Anne-Sophie; Morisse, Mony Chenda; Mammeri, Youcef; Galmiche, Antoine

    2017-12-01

    Recent progress in biology has made the study of the medical treatment of cancer more effective, but it has also revealed the large complexity of carcinogenesis and cell signaling. For many types of cancer, several therapeutic targets are known and in some cases drugs against these targets exist. Unfortunately, the target proteins often work in networks, resulting in functional adaptation and the development of resilience/resistance to medical treatment. The use of mathematical modeling makes it possible to carry out system-level analyses for improved study of therapeutic targeting in solid tumours. We present the main types of mathematical models used in cancer research and we provide examples illustrating the relevance of these approaches in molecular oncobiology. © 2017 médecine/sciences – Inserm.

  2. Mathematical analysis of frontal affinity chromatography in particle and membrane configurations.

    PubMed

    Tejeda-Mansir, A; Montesinos, R M; Guzmán, R

    2001-10-30

    The scaleup and optimization of large-scale affinity-chromatographic operations in the recovery, separation and purification of biochemical components is of major industrial importance. The development of mathematical models to describe affinity-chromatographic processes, and the use of these models in computer programs to predict column performance is an engineering approach that can help to attain these bioprocess engineering tasks successfully. Most affinity-chromatographic separations are operated in the frontal mode, using fixed-bed columns. Purely diffusive and perfusion particles and membrane-based affinity chromatography are among the main commercially available technologies for these separations. For a particular application, a basic understanding of the main similarities and differences between particle and membrane frontal affinity chromatography and how these characteristics are reflected in the transport models is of fundamental relevance. This review presents the basic theoretical considerations used in the development of particle and membrane affinity chromatography models that can be applied in the design and operation of large-scale affinity separations in fixed-bed columns. A transport model for column affinity chromatography that considers column dispersion, particle internal convection, external film resistance, finite kinetic rate, plus macropore and micropore resistances is analyzed as a framework for exploring further the mathematical analysis. Such models provide a general realistic description of almost all practical systems. Specific mathematical models that take into account geometric considerations and transport effects have been developed for both particle and membrane affinity chromatography systems. Some of the most common simplified models, based on linear driving-force (LDF) and equilibrium assumptions, are emphasized. Analytical solutions of the corresponding simplified dimensionless affinity models are presented. Particular methods for estimating the parameters that characterize the mass-transfer and adsorption mechanisms in affinity systems are described.

  3. Biophysically based mathematical modeling of interstitial cells of Cajal slow wave activity generated from a discrete unitary potential basis.

    PubMed

    Faville, R A; Pullan, A J; Sanders, K M; Koh, S D; Lloyd, C M; Smith, N P

    2009-06-17

    Spontaneously rhythmic pacemaker activity produced by interstitial cells of Cajal (ICC) is the result of the entrainment of unitary potential depolarizations generated at intracellular sites termed pacemaker units. In this study, we present a mathematical modeling framework that quantitatively represents the transmembrane ion flows and intracellular Ca2+ dynamics from a single ICC operating over the physiological membrane potential range. The mathematical model presented here extends our recently developed biophysically based pacemaker unit modeling framework by including mechanisms necessary for coordinating unitary potential events, such as a T-Type Ca2+ current, Vm-dependent K+ currents, and global Ca2+ diffusion. Model simulations produce spontaneously rhythmic slow wave depolarizations with an amplitude of 65 mV at a frequency of 17.4 cpm. Our model predicts that activity at the spatial scale of the pacemaker unit is fundamental for ICC slow wave generation, and Ca2+ influx from activation of the T-Type Ca2+ current is required for unitary potential entrainment. These results suggest that intracellular Ca2+ levels, particularly in the region local to the mitochondria and endoplasmic reticulum, significantly influence pacing frequency and synchronization of pacemaker unit discharge. Moreover, numerical investigations show that our ICC model is capable of qualitatively replicating a wide range of experimental observations.

  4. A magneto-rheological fluid mount featuring squeeze mode: analysis and testing

    NASA Astrophysics Data System (ADS)

    Chen, Peng; Bai, Xian-Xu; Qian, Li-Jun; Choi, Seung-Bok

    2016-05-01

    This paper presents a mathematical model for a new semi-active vehicle engine mount utilizing magneto-rheological (MR) fluids in squeeze mode (MR mount in short) and validates the model by comparing analysis results with experimental tests. The proposed MR mount is mainly comprised of a frame for installation, a main rubber, a squeeze plate and a bobbin for coil winding. When the magnetic fields on, MR effect occurs in the upper gap between the squeeze plate and the bobbin, and the dynamic stiffness can be controlled by tuning the applied currents. Employing Bingham model and flow properties between parallel plates of MR fluids, a mathematical model for the squeeze type of MR mount is formulated with consideration of the fluid inertia, MR effect and hysteresis property. The field-dependent dynamic stiffness of the MR mount is then analyzed using the established mathematical model. Subsequently, in order to validate the mathematical model, an appropriate size of MR mount is fabricated and tested. The field-dependent force and dynamic stiffness of the proposed MR mount are evaluated and compared between the model and experimental tests in both time and frequency domains to verify the model efficiency. In addition, it is shown that both the damping property and the stiffness property of the proposed MR mount can be simultaneously controlled.

  5. Defining Computational Thinking for Mathematics and Science Classrooms

    NASA Astrophysics Data System (ADS)

    Weintrop, David; Beheshti, Elham; Horn, Michael; Orton, Kai; Jona, Kemi; Trouille, Laura; Wilensky, Uri

    2016-02-01

    Science and mathematics are becoming computational endeavors. This fact is reflected in the recently released Next Generation Science Standards and the decision to include "computational thinking" as a core scientific practice. With this addition, and the increased presence of computation in mathematics and scientific contexts, a new urgency has come to the challenge of defining computational thinking and providing a theoretical grounding for what form it should take in school science and mathematics classrooms. This paper presents a response to this challenge by proposing a definition of computational thinking for mathematics and science in the form of a taxonomy consisting of four main categories: data practices, modeling and simulation practices, computational problem solving practices, and systems thinking practices. In formulating this taxonomy, we draw on the existing computational thinking literature, interviews with mathematicians and scientists, and exemplary computational thinking instructional materials. This work was undertaken as part of a larger effort to infuse computational thinking into high school science and mathematics curricular materials. In this paper, we argue for the approach of embedding computational thinking in mathematics and science contexts, present the taxonomy, and discuss how we envision the taxonomy being used to bring current educational efforts in line with the increasingly computational nature of modern science and mathematics.

  6. Energy-technological complex with reactor for torrefaction

    NASA Astrophysics Data System (ADS)

    Kuzmina, J. S.; Director, L. B.; Zaichenko, V. M.

    2016-11-01

    To eliminate shortcomings of raw plant materials pelletizing process with thermal treatment (low-temperature pyrolysis or torrefaction) can be applied. This paper presents a mathematical model of energy-technological complex (ETC) for combined production of heat, electricity and solid biofuels torrefied pellets. According to the structure the mathematical model consists of mathematical models of main units of ETC and the relationships between them and equations of energy and material balances. The equations describe exhaust gas straining action through a porous medium formed by pellets. Decomposition rate of biomass was calculated by using the gross-reaction diagram, which is responsible for the disintegration of raw material. A mathematical model has been tested according to bench experiments on one reactor module. From nomographs, designed for a particular configuration of ETC it is possible to determine the basic characteristics of torrefied pellets (rate of weight loss, heating value and heat content) specifying only two parameters (temperature and torrefaction time). It is shown that the addition of reactor for torrefaction to gas piston engine can improve the energy efficiency of power plant.

  7. Information modeling system for blast furnace control

    NASA Astrophysics Data System (ADS)

    Spirin, N. A.; Gileva, L. Y.; Lavrov, V. V.

    2016-09-01

    Modern Iron & Steel Works as a rule are equipped with powerful distributed control systems (DCS) and databases. Implementation of DSC system solves the problem of storage, control, protection, entry, editing and retrieving of information as well as generation of required reporting data. The most advanced and promising approach is to use decision support information technologies based on a complex of mathematical models. The model decision support system for control of blast furnace smelting is designed and operated. The basis of the model system is a complex of mathematical models created using the principle of natural mathematical modeling. This principle provides for construction of mathematical models of two levels. The first level model is a basic state model which makes it possible to assess the vector of system parameters using field data and blast furnace operation results. It is also used to calculate the adjustment (adaptation) coefficients of the predictive block of the system. The second-level model is a predictive model designed to assess the design parameters of the blast furnace process when there are changes in melting conditions relative to its current state. Tasks for which software is developed are described. Characteristics of the main subsystems of the blast furnace process as an object of modeling and control - thermal state of the furnace, blast, gas dynamic and slag conditions of blast furnace smelting - are presented.

  8. Mathematical Modeling in Mathematics Education: Basic Concepts and Approaches

    ERIC Educational Resources Information Center

    Erbas, Ayhan Kürsat; Kertil, Mahmut; Çetinkaya, Bülent; Çakiroglu, Erdinç; Alacaci, Cengiz; Bas, Sinem

    2014-01-01

    Mathematical modeling and its role in mathematics education have been receiving increasing attention in Turkey, as in many other countries. The growing body of literature on this topic reveals a variety of approaches to mathematical modeling and related concepts, along with differing perspectives on the use of mathematical modeling in teaching and…

  9. Elementary Preservice Teachers' and Elementary Inservice Teachers' Knowledge of Mathematical Modeling

    ERIC Educational Resources Information Center

    Schwerdtfeger, Sara

    2017-01-01

    This study examined the differences in knowledge of mathematical modeling between a group of elementary preservice teachers and a group of elementary inservice teachers. Mathematical modeling has recently come to the forefront of elementary mathematics classrooms because of the call to add mathematical modeling tasks in mathematics classes through…

  10. A Case Study of Teachers' Development of Well-Structured Mathematical Modelling Activities

    ERIC Educational Resources Information Center

    Stohlmann, Micah; Maiorca, Cathrine; Allen, Charlie

    2017-01-01

    This case study investigated how three teachers developed mathematical modelling activities integrated with content standards through participation in a course on mathematical modelling. The class activities involved experiencing a mathematical modelling activity, reading and rating example mathematical modelling activities, reading articles about…

  11. Understanding the dynamics of sustainable social-ecological systems: human behavior, institutions, and regulatory feedback networks.

    PubMed

    Anderies, John M

    2015-02-01

    I present a general mathematical modeling framework that can provide a foundation for the study of sustainability in social- ecological systems (SESs). Using basic principles from feedback control and a sequence of specific models from bioeconomics and economic growth, I outline several mathematical and empirical challenges associated with the study of sustainability of SESs. These challenges are categorized into three classes: (1) the social choice of performance measures, (2) uncertainty, and (3) collective action. Finally, I present some opportunities for combining stylized dynamical systems models with empirical data on human behavior and biophysical systems to address practical challenges for the design of effective governance regimes (policy feedbacks) for highly uncertain natural resource systems.

  12. Mathematics as a conduit for translational research in post-traumatic osteoarthritis.

    PubMed

    Ayati, Bruce P; Kapitanov, Georgi I; Coleman, Mitchell C; Anderson, Donald D; Martin, James A

    2017-03-01

    Biomathematical models offer a powerful method of clarifying complex temporal interactions and the relationships among multiple variables in a system. We present a coupled in silico biomathematical model of articular cartilage degeneration in response to impact and/or aberrant loading such as would be associated with injury to an articular joint. The model incorporates fundamental biological and mechanical information obtained from explant and small animal studies to predict post-traumatic osteoarthritis (PTOA) progression, with an eye toward eventual application in human patients. In this sense, we refer to the mathematics as a "conduit of translation." The new in silico framework presented in this paper involves a biomathematical model for the cellular and biochemical response to strains computed using finite element analysis. The model predicts qualitative responses presently, utilizing system parameter values largely taken from the literature. To contribute to accurate predictions, models need to be accurately parameterized with values that are based on solid science. We discuss a parameter identification protocol that will enable us to make increasingly accurate predictions of PTOA progression using additional data from smaller scale explant and small animal assays as they become available. By distilling the data from the explant and animal assays into parameters for biomathematical models, mathematics can translate experimental data to clinically relevant knowledge. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:566-572, 2017. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc.

  13. PENDISC: a simple method for constructing a mathematical model from time-series data of metabolite concentrations.

    PubMed

    Sriyudthsak, Kansuporn; Iwata, Michio; Hirai, Masami Yokota; Shiraishi, Fumihide

    2014-06-01

    The availability of large-scale datasets has led to more effort being made to understand characteristics of metabolic reaction networks. However, because the large-scale data are semi-quantitative, and may contain biological variations and/or analytical errors, it remains a challenge to construct a mathematical model with precise parameters using only these data. The present work proposes a simple method, referred to as PENDISC (Parameter Estimation in a N on- DImensionalized S-system with Constraints), to assist the complex process of parameter estimation in the construction of a mathematical model for a given metabolic reaction system. The PENDISC method was evaluated using two simple mathematical models: a linear metabolic pathway model with inhibition and a branched metabolic pathway model with inhibition and activation. The results indicate that a smaller number of data points and rate constant parameters enhances the agreement between calculated values and time-series data of metabolite concentrations, and leads to faster convergence when the same initial estimates are used for the fitting. This method is also shown to be applicable to noisy time-series data and to unmeasurable metabolite concentrations in a network, and to have a potential to handle metabolome data of a relatively large-scale metabolic reaction system. Furthermore, it was applied to aspartate-derived amino acid biosynthesis in Arabidopsis thaliana plant. The result provides confirmation that the mathematical model constructed satisfactorily agrees with the time-series datasets of seven metabolite concentrations.

  14. Mathematical Modelling Approach in Mathematics Education

    ERIC Educational Resources Information Center

    Arseven, Ayla

    2015-01-01

    The topic of models and modeling has come to be important for science and mathematics education in recent years. The topic of "Modeling" topic is especially important for examinations such as PISA which is conducted at an international level and measures a student's success in mathematics. Mathematical modeling can be defined as using…

  15. Mathematical Modelling in the Junior Secondary Years: An Approach Incorporating Mathematical Technology

    ERIC Educational Resources Information Center

    Lowe, James; Carter, Merilyn; Cooper, Tom

    2018-01-01

    Mathematical models are conceptual processes that use mathematics to describe, explain, and/or predict the behaviour of complex systems. This article is written for teachers of mathematics in the junior secondary years (including out-of-field teachers of mathematics) who may be unfamiliar with mathematical modelling, to explain the steps involved…

  16. Mathematics teachers' conceptions about modelling activities and its reflection on their beliefs about mathematics

    NASA Astrophysics Data System (ADS)

    Shahbari, Juhaina Awawdeh

    2018-07-01

    The current study examines whether the engagement of mathematics teachers in modelling activities and subsequent changes in their conceptions about these activities affect their beliefs about mathematics. The sample comprised 52 mathematics teachers working in small groups in four modelling activities. The data were collected from teachers' Reports about features of each activity, interviews and questionnaires on teachers' beliefs about mathematics. The findings indicated changes in teachers' conceptions about the modelling activities. Most teachers referred to the first activity as a mathematical problem but emphasized only the mathematical notions or the mathematical operations in the modelling process; changes in their conceptions were gradual. Most of the teachers referred to the fourth activity as a mathematical problem and emphasized features of the whole modelling process. The results of the interviews indicated that changes in the teachers' conceptions can be attributed to structure of the activities, group discussions, solution paths and elicited models. These changes about modelling activities were reflected in teachers' beliefs about mathematics. The quantitative findings indicated that the teachers developed more constructive beliefs about mathematics after engagement in the modelling activities and that the difference was significant, however there was no significant difference regarding changes in their traditional beliefs.

  17. A Practitioner's Instrument for Measuring Secondary Mathematics Teachers' Beliefs Surrounding Learner-Centered Classroom Practice.

    PubMed

    Lischka, Alyson E; Garner, Mary

    In this paper we present the development and validation of a Mathematics Teaching Pedagogical and Discourse Beliefs Instrument (MTPDBI), a 20 item partial-credit survey designed and analyzed using Rasch measurement theory. Items on the MTPDBI address beliefs about the nature of mathematics, teaching and learning mathematics, and classroom discourse practices. A Rasch partial credit model (Masters, 1982) was estimated from the pilot study data. Results show that item separation reliability is .96 and person separation reliability is .71. Other analyses indicate the instrument is a viable measure of secondary teachers' beliefs about reform-oriented mathematics teaching and learning. This instrument is proposed as a useful measure of teacher beliefs for those working with pre-service and in-service teacher development.

  18. Modeling and simulation in biomedicine.

    PubMed Central

    Aarts, J.; Möller, D.; van Wijk van Brievingh, R.

    1991-01-01

    A group of researchers and educators in The Netherlands, Germany and Czechoslovakia have developed and adapted mathematical computer models of phenomena in the field of physiology and biomedicine for use in higher education. The models are graphical and highly interactive, and are all written in TurboPascal or the mathematical simulation language PSI. An educational shell has been developed to launch the models. The shell allows students to interact with the models and teachers to edit the models, to add new models and to monitor the achievements of the students. The models and the shell have been implemented on a MS-DOS personal computer. This paper describes the features of the modeling package and presents the modeling and simulation of the heart muscle as an example. PMID:1807745

  19. A Teachable-Agent-Based Game Affording Collaboration and Competition: Evaluating Math Comprehension and Motivation

    ERIC Educational Resources Information Center

    Pareto, Lena; Haake, Magnus; Lindstrom, Paulina; Sjoden, Bjorn; Gulz, Agneta

    2012-01-01

    This paper presents an educational game in mathematics based on an apprenticeship model using a teachable agent, as well as an evaluative study of how the game affects (1) conceptual understanding and (2) attitudes towards mathematics. In addition, we discuss how collaborative and competitive affordances of the game may affect understanding and…

  20. Knowing and Teaching Fractions: A Cross-Cultural Study of American and Chinese Mathematics Teachers

    ERIC Educational Resources Information Center

    Zhou, Zheng; Peverly, Stephen T.; Xin, Tao

    2006-01-01

    Guided by Shulman, 1986 and Shulman, 1987 tripartate model of teacher expertise [subject matter knowledge (SMK), pedagogical content knowledge (PCK), and general pedagogical knowledge (GPK)], the present study examined 162 U.S. and Chinese 3rd grade mathematics teachers' expertise in teaching fractions. Results show that U.S. teachers lag…

  1. Alleviating Mathematics Anxiety of Elementary School Students: A Situated Perspective

    ERIC Educational Resources Information Center

    Sharma, Yogesh

    2016-01-01

    The present study investigates the effects of the situated learning and effortful control on mathematics anxiety of school students. Participants were 99 seventh graders who studied in two schools. Students in one of these were given instruction through the situated learning model, and the students of other school were treated as a control group.…

  2. Near-earth orbital guidance and remote sensing

    NASA Technical Reports Server (NTRS)

    Powers, W. F.

    1972-01-01

    The curriculum of a short course in remote sensing and parameter optimization is presented. The subjects discussed are: (1) basics of remote sensing and the user community, (2) multivariant spectral analysis, (3) advanced mathematics and physics of remote sensing, (4) the atmospheric environment, (5) imaging sensing, and (6)nonimaging sensing. Mathematical models of optimization techniques are developed.

  3. Developing teaching process for enhancing students' mathematical problem solving in the 21st century through STEM education

    NASA Astrophysics Data System (ADS)

    Prawvichien, Sutthaporn; Siripun, Kulpatsorn; Yuenyong, Chokchai

    2018-01-01

    The STEM education could provide the context for students' learning in the 21st century. The Mathematical problem solving requires a context which simulates real life in order to give students experience of the power of mathematics in the world around them. This study aimed to develop the teaching process for enhancing students' mathematical problem solving in the 21st century through STEM education. The paper will clarify the STEM learning activities about graph theories regarding on the 6 steps of engineering design process. These include identify a challenge, exploring ideas, designing and planning, doing and developing, test and evaluate, and present the solution. The learning activities will start from the Identify a challenge stage which provides the northern part of Thailand flooding situation in order to set the students' tasks of develop the solutions of providing the routes of fastest moving people away from the flooding areas. The explore ideas stage will provide activities for enhance students to learn some knowledge based for designing the possible solutions. This knowledge based could focus on measuring, geometry, graph theory, and mathematical process. The design and plan stage will ask students to model the city based on the map and then provide the possible routes. The doing and development stage will ask students to develop the routes based on their possible model. The test and evaluating will ask students to clarify how to test and evaluate the possible routes, and then test it. The present solution stage will ask students to present the whole process of designing routes. Then, the paper will discuss how these learning activities could enhance students' mathematical problem solving. The paper may have implication for STEM education in school setting.

  4. Numerical modeling and preliminary validation of drag-based vertical axis wind turbine

    NASA Astrophysics Data System (ADS)

    Krysiński, Tomasz; Buliński, Zbigniew; Nowak, Andrzej J.

    2015-03-01

    The main purpose of this article is to verify and validate the mathematical description of the airflow around a wind turbine with vertical axis of rotation, which could be considered as representative for this type of devices. Mathematical modeling of the airflow around wind turbines in particular those with the vertical axis is a problematic matter due to the complex nature of this highly swirled flow. Moreover, it is turbulent flow accompanied by a rotation of the rotor and the dynamic boundary layer separation. In such conditions, the key aspects of the mathematical model are accurate turbulence description, definition of circular motion as well as accompanying effects like centrifugal force or the Coriolis force and parameters of spatial and temporal discretization. The paper presents the impact of the different simulation parameters on the obtained results of the wind turbine simulation. Analysed models have been validated against experimental data published in the literature.

  5. Experimental and mathematical model of the interactions in the mixed culture of links in the “producer-consumer” cycle

    NASA Astrophysics Data System (ADS)

    Pisman, T. I.

    2009-07-01

    The paper presents a experimental and mathematical model of interactions between invertebrates (the ciliates Paramecium caudatum and the rotifers Brachionus plicatilis) in the "producer-consumer" aquatic biotic cycle with spatially separated components. The model describes the dynamics of the mixed culture of ciliates and rotifers in the "consumer" component, feeding on the mixed algal culture of the "producer" component. It has been found that metabolites of the algae Scenedesmus produce an adverse effect on the reproduction of the ciliates P. caudatum. Taking into account this effect, the results of investigation of the mathematical model were in qualitative agreement with the experimental results. In the "producer-consumer" biotic cycle it was shown that coexistence is impossible in the mixed culture of invertebrates of the "consumer" component. The ciliates P. caudatum are driven out by the rotifers B. plicatilis.

  6. Modeling of Semiconductor Optical Amplifier Gain Characteristics for Amplification and Switching

    NASA Astrophysics Data System (ADS)

    Mahad, Farah Diana; Sahmah, Abu; Supa'at, M.; Idrus, Sevia Mahdaliza; Forsyth, David

    2011-05-01

    The Semiconductor Optical Amplifier (SOA) is presently commonly used as a booster or pre-amplifier in some communication networks. However, SOAs are also a strong candidate for utilization as multi-functional elements in future all-optical switching, regeneration and also wavelength conversion schemes. With this in mind, the purpose of this paper is to simulate the performance of the SOA for improved amplification and switching functions. The SOA is modeled and simulated using OptSim software. In order to verify the simulated results, a MATLAB mathematical model is also used to aid the design of the SOA. Using the model, the gain difference between simulated and mathematical results in the unsaturated region is <1dB. The mathematical analysis is in good agreement with the simulation result, with only a small offset due to inherent software limitations in matching the gain dynamics of the SOA.

  7. Puerto Rico water resources planning model program description

    USGS Publications Warehouse

    Moody, D.W.; Maddock, Thomas; Karlinger, M.R.; Lloyd, J.J.

    1973-01-01

    Because the use of the Mathematical Programming System -Extended (MPSX) to solve large linear and mixed integer programs requires the preparation of many input data cards, a matrix generator program to produce the MPSX input data from a much more limited set of data may expedite the use of the mixed integer programming optimization technique. The Model Definition and Control Program (MODCQP) is intended to assist a planner in preparing MPSX input data for the Puerto Rico Water Resources Planning Model. The model utilizes a mixed-integer mathematical program to identify a minimum present cost set of water resources projects (diversions, reservoirs, ground-water fields, desalinization plants, water treatment plants, and inter-basin transfers of water) which will meet a set of future water demands and to determine their sequence of construction. While MODCOP was specifically written to generate MPSX input data for the planning model described in this report, the program can be easily modified to reflect changes in the model's mathematical structure.

  8. Assessing metacognition of grade 2 and grade 4 students using an adaptation of multi-method interview approach during mathematics problem-solving

    NASA Astrophysics Data System (ADS)

    Kuzle, A.

    2018-06-01

    The important role that metacognition plays as a predictor for student mathematical learning and for mathematical problem-solving, has been extensively documented. But only recently has attention turned to primary grades, and more research is needed at this level. The goals of this paper are threefold: (1) to present metacognitive framework during mathematics problem-solving, (2) to describe their multi-method interview approach developed to study student mathematical metacognition, and (3) to empirically evaluate the utility of their model and the adaptation of their approach in the context of grade 2 and grade 4 mathematics problem-solving. The results are discussed not only with regard to further development of the adapted multi-method interview approach, but also with regard to their theoretical and practical implications.

  9. PREdator: a python based GUI for data analysis, evaluation and fitting

    PubMed Central

    2014-01-01

    The analysis of a series of experimental data is an essential procedure in virtually every field of research. The information contained in the data is extracted by fitting the experimental data to a mathematical model. The type of the mathematical model (linear, exponential, logarithmic, etc.) reflects the physical laws that underlie the experimental data. Here, we aim to provide a readily accessible, user-friendly python script for data analysis, evaluation and fitting. PREdator is presented at the example of NMR paramagnetic relaxation enhancement analysis.

  10. A mathematical model for computer image tracking.

    PubMed

    Legters, G R; Young, T Y

    1982-06-01

    A mathematical model using an operator formulation for a moving object in a sequence of images is presented. Time-varying translation and rotation operators are derived to describe the motion. A variational estimation algorithm is developed to track the dynamic parameters of the operators. The occlusion problem is alleviated by using a predictive Kalman filter to keep the tracking on course during severe occlusion. The tracking algorithm (variational estimation in conjunction with Kalman filter) is implemented to track moving objects with occasional occlusion in computer-simulated binary images.

  11. Mathematical modeling in biological populations through branching processes. Application to salmonid populations.

    PubMed

    Molina, Manuel; Mota, Manuel; Ramos, Alfonso

    2015-01-01

    This work deals with mathematical modeling through branching processes. We consider sexually reproducing animal populations where, in each generation, the number of progenitor couples is determined in a non-predictable environment. By using a class of two-sex branching processes, we describe their demographic dynamics and provide several probabilistic and inferential contributions. They include results about the extinction of the population and the estimation of the offspring distribution and its main moments. We also present an application to salmonid populations.

  12. A mathematical model of a steady flow through the Kaplan turbine - The existence of a weak solution in the case of an arbitrarily large inflow

    NASA Astrophysics Data System (ADS)

    Neustupa, Tomáš

    2017-07-01

    The paper presents the mathematical model of a steady 2-dimensional viscous incompressible flow through a radial blade machine. The corresponding boundary value problem is studied in the rotating frame. We provide the classical and weak formulation of the problem. Using a special form of the so called "artificial" or "natural" boundary condition on the outflow, we prove the existence of a weak solution for an arbitrarily large inflow.

  13. Application of a mathematical model for ergonomics in lean manufacturing.

    PubMed

    Botti, Lucia; Mora, Cristina; Regattieri, Alberto

    2017-10-01

    The data presented in this article are related to the research article "Integrating ergonomics and lean manufacturing principles in a hybrid assembly line" (Botti et al., 2017) [1]. The results refer to the application of the mathematical model for the design of lean processes in hybrid assembly lines, meeting both the lean principles and the ergonomic requirements for safe assembly work. Data show that the success of a lean strategy is possible when ergonomics of workers is a parameter of the assembly process design.

  14. Mathematical modeling of shell configurations made of homogeneous and composite materials experiencing intensive short actions and large displacements

    NASA Astrophysics Data System (ADS)

    Khairnasov, K. Z.

    2018-04-01

    The paper presents a mathematical model for solving the problem of behavior of shell configurations under the action of static and dynamic impacts. The problem is solved in geometrically nonlinear statement with regard to the finite element method. The composite structures with different material layers are considered. The obtained equations are used to study the behavior of shell configurations under the action of dynamic loads. The results agree well with the experimental data.

  15. Application of Mathematical and Three-Dimensional Computer Modeling Tools in the Planning of Processes of Fuel and Energy Complexes

    NASA Astrophysics Data System (ADS)

    Aksenova, Olesya; Nikolaeva, Evgenia; Cehlár, Michal

    2017-11-01

    This work aims to investigate the effectiveness of mathematical and three-dimensional computer modeling tools in the planning of processes of fuel and energy complexes at the planning and design phase of a thermal power plant (TPP). A solution for purification of gas emissions at the design development phase of waste treatment systems is proposed employing mathematical and three-dimensional computer modeling - using the E-nets apparatus and the development of a 3D model of the future gas emission purification system. Which allows to visualize the designed result, to select and scientifically prove economically feasible technology, as well as to ensure the high environmental and social effect of the developed waste treatment system. The authors present results of a treatment of planned technological processes and the system for purifying gas emissions in terms of E-nets. using mathematical modeling in the Simulink application. What allowed to create a model of a device from the library of standard blocks and to perform calculations. A three-dimensional model of a system for purifying gas emissions has been constructed. It allows to visualize technological processes and compare them with the theoretical calculations at the design phase of a TPP and. if necessary, make adjustments.

  16. A Simple Mathematical Model for Standard Model of Elementary Particles and Extension Thereof

    NASA Astrophysics Data System (ADS)

    Sinha, Ashok

    2016-03-01

    An algebraically (and geometrically) simple model representing the masses of the elementary particles in terms of the interaction (strong, weak, electromagnetic) constants is developed, including the Higgs bosons. The predicted Higgs boson mass is identical to that discovered by LHC experimental programs; while possibility of additional Higgs bosons (and their masses) is indicated. The model can be analyzed to explain and resolve many puzzles of particle physics and cosmology including the neutrino masses and mixing; origin of the proton mass and the mass-difference between the proton and the neutron; the big bang and cosmological Inflation; the Hubble expansion; etc. A novel interpretation of the model in terms of quaternion and rotation in the six-dimensional space of the elementary particle interaction-space - or, equivalently, in six-dimensional spacetime - is presented. Interrelations among particle masses are derived theoretically. A new approach for defining the interaction parameters leading to an elegant and symmetrical diagram is delineated. Generalization of the model to include supersymmetry is illustrated without recourse to complex mathematical formulation and free from any ambiguity. This Abstract represents some results of the Author's Independent Theoretical Research in Particle Physics, with possible connection to the Superstring Theory. However, only very elementary mathematics and physics is used in my presentation.

  17. Catastrophic event modeling. [lithium thionyl chloride batteries

    NASA Technical Reports Server (NTRS)

    Frank, H. A.

    1981-01-01

    A mathematical model for the catastrophic failures (venting or explosion of the cell) in lithium thionyl chloride batteries is presented. The phenomenology of the various processes leading to cell failure is reviewed.

  18. Course Cost Modelling in Australian Tertiary Education.

    ERIC Educational Resources Information Center

    Sharma, Raj

    1986-01-01

    A mathematical model for costing college courses, designed for purposes of accountability, subprogram cost analysis, marketing to foreign students (in Australia), and course cost analysis across institutions, is presented and discussed. (MSE)

  19. The 24-Hour Mathematical Modeling Challenge

    ERIC Educational Resources Information Center

    Galluzzo, Benjamin J.; Wendt, Theodore J.

    2015-01-01

    Across the mathematics curriculum there is a renewed emphasis on applications of mathematics and on mathematical modeling. Providing students with modeling experiences beyond the ordinary classroom setting remains a challenge, however. In this article, we describe the 24-hour Mathematical Modeling Challenge, an extracurricular event that exposes…

  20. Granularity analysis for mathematical proofs.

    PubMed

    Schiller, Marvin R G

    2013-04-01

    Mathematical proofs generally allow for various levels of detail and conciseness, such that they can be adapted for a particular audience or purpose. Using automated reasoning approaches for teaching proof construction in mathematics presupposes that the step size of proofs in such a system is appropriate within the teaching context. This work proposes a framework that supports the granularity analysis of mathematical proofs, to be used in the automated assessment of students' proof attempts and for the presentation of hints and solutions at a suitable pace. Models for granularity are represented by classifiers, which can be generated by hand or inferred from a corpus of sample judgments via machine-learning techniques. This latter procedure is studied by modeling granularity judgments from four experts. The results provide support for the granularity of assertion-level proofs but also illustrate a degree of subjectivity in assessing step size. Copyright © 2013 Cognitive Science Society, Inc.

  1. Earth and ocean modeling

    NASA Technical Reports Server (NTRS)

    Knezovich, F. M.

    1976-01-01

    A modular structured system of computer programs is presented utilizing earth and ocean dynamical data keyed to finitely defined parameters. The model is an assemblage of mathematical algorithms with an inherent capability of maturation with progressive improvements in observational data frequencies, accuracies and scopes. The Eom in its present state is a first-order approach to a geophysical model of the earth's dynamics.

  2. Preliminary eddy current modelling for the large angle magnetic suspension test fixture

    NASA Technical Reports Server (NTRS)

    Britcher, Colin

    1994-01-01

    This report presents some recent developments in the mathematical modeling of the Large Angle Magnetic Suspension Test Fixture (LAMSTF) at NASA Langley Research Center. It is shown that these effects are significant, but may be amenable to analysis, modeling and measurement. A theoretical framework is presented, together with a comparison of computed and experimental data.

  3. The Relationship between Students' Performance on Conventional Standardized Mathematics Assessments and Complex Mathematical Modeling Problems

    ERIC Educational Resources Information Center

    Kartal, Ozgul; Dunya, Beyza Aksu; Diefes-Dux, Heidi A.; Zawojewski, Judith S.

    2016-01-01

    Critical to many science, technology, engineering, and mathematics (STEM) career paths is mathematical modeling--specifically, the creation and adaptation of mathematical models to solve problems in complex settings. Conventional standardized measures of mathematics achievement are not structured to directly assess this type of mathematical…

  4. Annual Perspectives in Mathematics Education 2016: Mathematical Modeling and Modeling Mathematics

    ERIC Educational Resources Information Center

    Hirsch, Christian R., Ed.; McDuffie, Amy Roth, Ed.

    2016-01-01

    Mathematical modeling plays an increasingly important role both in real-life applications--in engineering, business, the social sciences, climate study, advanced design, and more--and within mathematics education itself. This 2016 volume of "Annual Perspectives in Mathematics Education" ("APME") focuses on this key topic from a…

  5. A Gambler's Model of Natural Selection.

    ERIC Educational Resources Information Center

    Nolan, Michael J.; Ostrovsky, David S.

    1996-01-01

    Presents an activity that highlights the mechanism and power of natural selection. Allows students to think in terms of modeling a biological process and instills an appreciation for a mathematical approach to biological problems. (JRH)

  6. Variable thickness transient ground-water flow model. Volume 1. Formulation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reisenauer, A.E.

    1979-12-01

    Mathematical formulation for the variable thickness transient (VTT) model of an aquifer system is presented. The basic assumptions are described. Specific data requirements for the physical parameters are discussed. The boundary definitions and solution techniques of the numerical formulation of the system of equations are presented.

  7. Angular motion equations for a satellite with hinged flexible solar panel

    NASA Astrophysics Data System (ADS)

    Ovchinnikov, M. Yu.; Tkachev, S. S.; Roldugin, D. S.; Nuralieva, A. B.; Mashtakov, Y. V.

    2016-11-01

    Non-linear mathematical model for the satellite with hinged flexible solar panel is presented. Normal modes of flexible elements are used for motion description. Motion equations are derived using virtual work principle. A comparison of normal modes calculation between finite element method and developed model is presented.

  8. Uncertainty Quantification in Simulations of Epidemics Using Polynomial Chaos

    PubMed Central

    Santonja, F.; Chen-Charpentier, B.

    2012-01-01

    Mathematical models based on ordinary differential equations are a useful tool to study the processes involved in epidemiology. Many models consider that the parameters are deterministic variables. But in practice, the transmission parameters present large variability and it is not possible to determine them exactly, and it is necessary to introduce randomness. In this paper, we present an application of the polynomial chaos approach to epidemiological mathematical models based on ordinary differential equations with random coefficients. Taking into account the variability of the transmission parameters of the model, this approach allows us to obtain an auxiliary system of differential equations, which is then integrated numerically to obtain the first-and the second-order moments of the output stochastic processes. A sensitivity analysis based on the polynomial chaos approach is also performed to determine which parameters have the greatest influence on the results. As an example, we will apply the approach to an obesity epidemic model. PMID:22927889

  9. Mathematical modeling of the integrated process of mercury bioremediation in the industrial bioreactor.

    PubMed

    Głuszcz, Paweł; Petera, Jerzy; Ledakowicz, Stanisław

    2011-03-01

    The mathematical model of the integrated process of mercury contaminated wastewater bioremediation in a fixed-bed industrial bioreactor is presented. An activated carbon packing in the bioreactor plays the role of an adsorbent for ionic mercury and at the same time of a carrier material for immobilization of mercury-reducing bacteria. The model includes three basic stages of the bioremediation process: mass transfer in the liquid phase, adsorption of mercury onto activated carbon and ionic mercury bioreduction to Hg(0) by immobilized microorganisms. Model calculations were verified using experimental data obtained during the process of industrial wastewater bioremediation in the bioreactor of 1 m³ volume. It was found that the presented model reflects the properties of the real system quite well. Numerical simulation of the bioremediation process confirmed the experimentally observed positive effect of the integration of ionic mercury adsorption and bioreduction in one apparatus.

  10. An Approach for a Mathematical Description of Human Root Canals by Means of Elementary Parameters.

    PubMed

    Dannemann, Martin; Kucher, Michael; Kirsch, Jasmin; Binkowski, Alexander; Modler, Niels; Hannig, Christian; Weber, Marie-Theres

    2017-04-01

    Root canal geometry is an important factor for instrumentation and preparation of the canals. Curvature, length, shape, and ramifications need to be evaluated in advance to enhance the success of the treatment. Therefore, the present study aimed to design and realize a method for analyzing the geometric characteristics of human root canals. Two extracted human lower molars were radiographed in the occlusal direction using micro-computed tomographic imaging. The 3-dimensional geometry of the root canals, calculated by a self-implemented image evaluation algorithm, was described by 3 different mathematical models: the elliptical model, the 1-circle model, and the 3-circle model. The different applied mathematical models obtained similar geometric properties depending on the parametric model used. Considering more complex root canals, the differences of the results increase because of the different adaptability and the better approximation of the geometry. With the presented approach, it is possible to estimate and compare the geometry of natural root canals. Therefore, the deviation of the canal can be assessed, which is important for the choice of taper of root canal instruments. Root canals with a nearly elliptical cross section are reasonably approximated by the elliptical model, whereas the 3-circle model obtains a good agreement for curved shapes. Copyright © 2017 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  11. Flight test planning and parameter extraction for rotorcraft system identification

    NASA Technical Reports Server (NTRS)

    Wang, J. C.; Demiroz, M. Y.; Talbot, P. D.

    1986-01-01

    The present study is concerned with the mathematical modelling of aircraft dynamics on the basis of an investigation conducted with the aid of the Rotor System Research Aircraft (RSRA). The particular characteristics of RSRA make it possible to investigate aircraft properties which cannot be readily studied elsewhere, for example in the wind tunnel. The considered experiment had mainly the objective to develop an improved understanding of the physics of rotor flapping dynamics and rotor loads in maneuvers. The employed approach is based on a utilization of parameter identification methodology (PID) with application to helicopters. A better understanding of the contribution of the main rotor to the overall aircraft forces and moments is also to be obtained. Attention is given to the mathematical model of a rotorcraft system, an integrated identification method, flight data processing, and the identification of RSRA mathematical models.

  12. Evaluation of the Thermodynamic Consistency of Closure Approximations in Several Models Proposed for the Description of Liquid Crystalline Dynamics

    NASA Astrophysics Data System (ADS)

    Edwards, Brian J.

    2002-05-01

    Given the premise that a set of dynamical equations must possess a definite, underlying mathematical structure to ensure local and global thermodynamic stability, as has been well documented, several different models for describing liquid crystalline dynamics are examined with respect to said structure. These models, each derived during the past several years using a specific closure approximation for the fourth moment of the distribution function in Doi's rigid rod theory, are all shown to be inconsistent with this basic mathematical structure. The source of this inconsistency lies in Doi's expressions for the extra stress tensor and temporal evolution of the order parameter, which are rederived herein using a transformation that allows for internal compatibility with the underlying mathematical structure that is present on the distribution function level of description.

  13. Mathematical Modeling: A Bridge to STEM Education

    ERIC Educational Resources Information Center

    Kertil, Mahmut; Gurel, Cem

    2016-01-01

    The purpose of this study is making a theoretical discussion on the relationship between mathematical modeling and integrated STEM education. First of all, STEM education perspective and the construct of mathematical modeling in mathematics education is introduced. A review of literature is provided on how mathematical modeling literature may…

  14. Modeling of the Temperature Field Recovery in the Oil Pool

    NASA Astrophysics Data System (ADS)

    Khabibullin, I. L.; Davtetbaev, A. Ya.; Mar'in, D. F.; Khisamov, A. A.

    2018-05-01

    This paper considers the problem on mathematical modeling of the temperature field recovery in the oil pool upon termination of injection of water into the pool. The problem is broken down into two stages: injection of water and temperature and pressure recovery upon termination of injection. A review of the existing mathematical models is presented, analytical solutions for a number of cases have been constructed, and a comparison of the analytical solutions of different models has been made. In the general form, the expression has been obtained that permits determining the temperature change in the oil pool upon termination of injection of water (recovery of the temperature field).

  15. Mathematical Modeling the Geometric Regularity in Proteus Mirabilis Colonies

    NASA Astrophysics Data System (ADS)

    Zhang, Bin; Jiang, Yi; Minsu Kim Collaboration

    Proteus Mirabilis colony exhibits striking spatiotemporal regularity, with concentric ring patterns with alternative high and low bacteria density in space, and periodicity for repetition process of growth and swarm in time. We present a simple mathematical model to explain the spatiotemporal regularity of P. Mirabilis colonies. We study a one-dimensional system. Using a reaction-diffusion model with thresholds in cell density and nutrient concentration, we recreated periodic growth and spread patterns, suggesting that the nutrient constraint and cell density regulation might be sufficient to explain the spatiotemporal periodicity in P. Mirabilis colonies. We further verify this result using a cell based model.

  16. One-dimensional nonlinear elastodynamic models and their local conservation laws with applications to biological membranes.

    PubMed

    Cheviakov, A F; Ganghoffer, J-F

    2016-05-01

    The framework of incompressible nonlinear hyperelasticity and viscoelasticity is applied to the derivation of one-dimensional models of nonlinear wave propagation in fiber-reinforced elastic solids. Equivalence transformations are used to simplify the resulting wave equations and to reduce the number of parameters. Local conservation laws and global conserved quantities of the models are systematically computed and discussed, along with other related mathematical properties. Sample numerical solutions are presented. The models considered in the paper are appropriate for the mathematical description of certain aspects of the behavior of biological membranes and similar structures. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Development and validation of a blade-element mathematical model for the AH-64A Apache helicopter

    NASA Technical Reports Server (NTRS)

    Mansur, M. Hossein

    1995-01-01

    A high-fidelity blade-element mathematical model for the AH-64A Apache Advanced Attack Helicopter has been developed by the Aeroflightdynamics Directorate of the U.S. Army's Aviation and Troop Command (ATCOM) at Ames Research Center. The model is based on the McDonnell Douglas Helicopter Systems' (MDHS) Fly Real Time (FLYRT) model of the AH-64A (acquired under contract) which was modified in-house and augmented with a blade-element-type main-rotor module. This report describes, in detail, the development of the rotor module, and presents some results of an extensive validation effort.

  18. Atmosphere behavior in gas-closed mouse-algal systems - An experimental and modelling study

    NASA Technical Reports Server (NTRS)

    Averner, M. M.; Moore, B., III; Bartholomew, I.; Wharton, R.

    1984-01-01

    A NASA-sponsored research program initiated using mathematical modelling and laboratory experimentation aimed at examining the gas-exchange characteristics of artificial animal/plant systems closed to the ambient atmosphere is studied. The development of control techniques and management strategies for maintaining the atmospheric levels of carbon dioxide and oxygen at physiological levels is considered. A mathematical model simulating the behavior of a gas-closed mouse-algal system under varying environmental conditions is described. To verify and validate the model simulations, an analytical system with which algal growth and gas exchange characteristics can be manipulated and measured is designed, fabricated, and tested. The preliminary results are presented.

  19. An investigation of the use of temporal decomposition in space mission scheduling

    NASA Technical Reports Server (NTRS)

    Bullington, Stanley E.; Narayanan, Venkat

    1994-01-01

    This research involves an examination of techniques for solving scheduling problems in long-duration space missions. The mission timeline is broken up into several time segments, which are then scheduled incrementally. Three methods are presented for identifying the activities that are to be attempted within these segments. The first method is a mathematical model, which is presented primarily to illustrate the structure of the temporal decomposition problem. Since the mathematical model is bound to be computationally prohibitive for realistic problems, two heuristic assignment procedures are also presented. The first heuristic method is based on dispatching rules for activity selection, and the second heuristic assigns performances of a model evenly over timeline segments. These heuristics are tested using a sample Space Station mission and a Spacelab mission. The results are compared with those obtained by scheduling the missions without any problem decomposition. The applicability of this approach to large-scale mission scheduling problems is also discussed.

  20. The influence of mathematics learning using SAVI approach on junior high school students’ mathematical modelling ability

    NASA Astrophysics Data System (ADS)

    Khusna, H.; Heryaningsih, N. Y.

    2018-01-01

    The aim of this research was to examine mathematical modeling ability who learn mathematics by using SAVI approach. This research was a quasi-experimental research with non-equivalent control group designed by using purposive sampling technique. The population of this research was the state junior high school students in Lembang while the sample consisted of two class at 8th grade. The instrument used in this research was mathematical modeling ability. Data analysis of this research was conducted by using SPSS 20 by Windows. The result showed that students’ ability of mathematical modeling who learn mathematics by using SAVI approach was better than students’ ability of mathematical modeling who learn mathematics using conventional learning.

  1. A discrete mathematical model for the aggregation of β-Amyloid.

    PubMed

    Dayeh, Maher A; Livadiotis, George; Elaydi, Saber

    2018-01-01

    Dementia associated with the Alzheimer's disease is thought to be correlated with the conversion of the β - Amyloid (Aβ) peptides from soluble monomers to aggregated oligomers and insoluble fibrils. We present a discrete-time mathematical model for the aggregation of Aβ monomers into oligomers using concepts from chemical kinetics and population dynamics. Conditions for the stability and instability of the equilibria of the model are established. A formula for the number of monomers that is required for producing oligomers is also given. This may provide compound designers a mechanism to inhibit the Aβ aggregation.

  2. An Overview of NASA's Orbital Debris Engineering Model

    NASA Technical Reports Server (NTRS)

    Matney, Mark

    2010-01-01

    This slide presentation reviews the importance of Orbital debris engineering models. They are mathematical tools to assess orbital debris flux. It briefly reviews the history of the orbital debris engineering models, and reviews the new features in the current model (i.e., ORDEM2010).

  3. Hydrogen production by the hyperthermophilic bacterium Thermotoga maritima Part II: modeling and experimental approaches for hydrogen production.

    PubMed

    Auria, Richard; Boileau, Céline; Davidson, Sylvain; Casalot, Laurence; Christen, Pierre; Liebgott, Pierre Pol; Combet-Blanc, Yannick

    2016-01-01

    Thermotoga maritima is a hyperthermophilic bacterium known to produce hydrogen from a large variety of substrates. The aim of the present study is to propose a mathematical model incorporating kinetics of growth, consumption of substrates, product formations, and inhibition by hydrogen in order to predict hydrogen production depending on defined culture conditions. Our mathematical model, incorporating data concerning growth, substrates, and products, was developed to predict hydrogen production from batch fermentations of the hyperthermophilic bacterium, T. maritima . It includes the inhibition by hydrogen and the liquid-to-gas mass transfer of H 2 , CO 2 , and H 2 S. Most kinetic parameters of the model were obtained from batch experiments without any fitting. The mathematical model is adequate for glucose, yeast extract, and thiosulfate concentrations ranging from 2.5 to 20 mmol/L, 0.2-0.5 g/L, or 0.01-0.06 mmol/L, respectively, corresponding to one of these compounds being the growth-limiting factor of T. maritima . When glucose, yeast extract, and thiosulfate concentrations are all higher than these ranges, the model overestimates all the variables. In the window of the model validity, predictions of the model show that the combination of both variables (increase in limiting factor concentration and in inlet gas stream) leads up to a twofold increase of the maximum H 2 -specific productivity with the lowest inhibition. A mathematical model predicting H 2 production in T. maritima was successfully designed and confirmed in this study. However, it shows the limit of validity of such mathematical models. Their limit of applicability must take into account the range of validity in which the parameters were established.

  4. Beyond Motivation: Exploring Mathematical Modeling as a Context for Deepening Students' Understandings of Curricular Mathematics

    ERIC Educational Resources Information Center

    Zbiek, Rose Mary; Conner, Annamarie

    2006-01-01

    Views of mathematical modeling in empirical, expository, and curricular references typically capture a relationship between real-world phenomena and mathematical ideas from the perspective that competence in mathematical modeling is a clear goal of the mathematics curriculum. However, we work within a curricular context in which mathematical…

  5. An Investigation of Mathematical Modeling with Pre-Service Secondary Mathematics Teachers

    ERIC Educational Resources Information Center

    Thrasher, Emily Plunkett

    2016-01-01

    The goal of this thesis was to investigate and enhance our understanding of what occurs while pre-service mathematics teachers engage in a mathematical modeling unit that is broadly based upon mathematical modeling as defined by the Common Core State Standards for Mathematics (National Governors Association Center for Best Practices & Council…

  6. The Latent Structure of Spatial Skills and Mathematics: A Replication of the Two-Factor Model

    ERIC Educational Resources Information Center

    Mix, Kelly S.; Levine, Susan C.; Cheng, Yi-Lang; Young, Christopher J.; Hambrick, David Z.; Konstantopoulos, Spyros

    2017-01-01

    In a previous study, Mix et al. (2016) reported that spatial skill and mathematics were composed of 2 highly correlated, domain-specific factors, with a few cross-domain loadings. The overall structure was consistent across grade (kindergarten, 3rd grade, 6th grade), but the cross-domain loadings varied with age. The present study sought to…

  7. Non-Lipschitz Dynamics Approach to Discrete Event Systems

    NASA Technical Reports Server (NTRS)

    Zak, M.; Meyers, R.

    1995-01-01

    This paper presents and discusses a mathematical formalism for simulation of discrete event dynamics (DED) - a special type of 'man- made' system designed to aid specific areas of information processing. A main objective is to demonstrate that the mathematical formalism for DED can be based upon the terminal model of Newtonian dynamics which allows one to relax Lipschitz conditions at some discrete points.

  8. Gender Difference Added? Institutional Variations in the Gender Gap in First Class Degree Awards in Mathematical Sciences

    ERIC Educational Resources Information Center

    Simonite, Vanessa

    2005-01-01

    This article shows how multilevel modelling can be used to study institutional variations in the gender differences in achievement. The results presented are from analyses of the degree classifications of 22,433 individuals who graduated in mathematical sciences, from universities in the UK, between 1994/95 and 1999/2000. The analyses were…

  9. Epistemological Beliefs of Prospective Preschool Teachers and Their Relation to Knowledge, Perception, and Planning Abilities in the Field of Mathematics: A Process Model

    ERIC Educational Resources Information Center

    Dunekacke, Simone; Jenßen, Lars; Eilerts, Katja; Blömeke, Sigrid

    2016-01-01

    Teacher competence is a multi-dimensional construct that includes beliefs as well as knowledge. The present study investigated the structure of prospective preschool teachers' mathematics-related beliefs and their relation to content knowledge and pedagogical content knowledge. In addition, prospective preschool teachers' perception and planning…

  10. Brief Report: Preliminary Proposal of a Conceptual Model of a Digital Environment for Developing Mathematical Reasoning in Students with Autism Spectrum Disorders

    ERIC Educational Resources Information Center

    Santos, Maria Isabel; Breda, Ana; Almeida, Ana Margarida

    2015-01-01

    There is clear evidence that in typically developing children reasoning and sense-making are essential in all mathematical learning and understanding processes. In children with autism spectrum disorders (ASD), however, these become much more significant, considering their importance to successful independent living. This paper presents a…

  11. Efficacy and efficiency in formative assessment: an informed reflection on the value of partial marking

    NASA Astrophysics Data System (ADS)

    Seaton, Katherine A.

    2013-10-01

    This article presents an informed reflection on the evolution of teacher-to-learner feedback provided on written assignments in first-year university mathematics subjects. The feedback provided addresses not only mathematical accuracy and skills, but also the development of graduate attributes, such as discipline-appropriate written communication. Effective and efficient practices that have been collectively refined and enhanced, for more than a decade, are described and examined. This model for formative assessment in mathematics subjects is critiqued in the light of the scholarly literature on feedback and assessment.

  12. Mathematical modeling of heat treatment processes conserving biological activity of plant bioresources

    NASA Astrophysics Data System (ADS)

    Rodionova, N. S.; Popov, E. S.; Pozhidaeva, E. A.; Pynzar, S. S.; Ryaskina, L. O.

    2018-05-01

    The aim of this study is to develop a mathematical model of the heat exchange process of LT-processing to estimate the dynamics of temperature field changes and optimize the regime parameters, due to the non-stationarity process, the physicochemical and thermophysical properties of food systems. The application of LT-processing, based on the use of low-temperature modes in thermal culinary processing of raw materials with preliminary vacuum packaging in a polymer heat- resistant film is a promising trend in the development of technics and technology in the catering field. LT-processing application of food raw materials guarantees the preservation of biologically active substances in food environments, which are characterized by a certain thermolability, as well as extend the shelf life and high consumer characteristics of food systems that are capillary-porous bodies. When performing the mathematical modeling of the LT-processing process, the packet of symbolic mathematics “Maple” was used, as well as the mathematical packet flexPDE that uses the finite element method for modeling objects with distributed parameters. The processing of experimental results was evaluated with the help of the developed software in the programming language Python 3.4. To calculate and optimize the parameters of the LT processing process of polycomponent food systems, the differential equation of non-stationary thermal conductivity was used, the solution of which makes it possible to identify the temperature change at any point of the solid at different moments. The present study specifies data on the thermophysical characteristics of the polycomponent food system based on plant raw materials, with the help of which the physico-mathematical model of the LT- processing process has been developed. The obtained mathematical model allows defining of the dynamics of the temperature field in different sections of the LT-processed polycomponent food systems on the basis of calculating the evolution profiles of temperature fields, which enable one to analyze the efficiency of the regime parameters of heat treatment.

  13. Ordinary differential equations with applications in molecular biology.

    PubMed

    Ilea, M; Turnea, M; Rotariu, M

    2012-01-01

    Differential equations are of basic importance in molecular biology mathematics because many biological laws and relations appear mathematically in the form of a differential equation. In this article we presented some applications of mathematical models represented by ordinary differential equations in molecular biology. The vast majority of quantitative models in cell and molecular biology are formulated in terms of ordinary differential equations for the time evolution of concentrations of molecular species. Assuming that the diffusion in the cell is high enough to make the spatial distribution of molecules homogenous, these equations describe systems with many participating molecules of each kind. We propose an original mathematical model with small parameter for biological phospholipid pathway. All the equations system includes small parameter epsilon. The smallness of epsilon is relative to the size of the solution domain. If we reduce the size of the solution region the same small epsilon will result in a different condition number. It is clear that the solution for a smaller region is less difficult. We introduce the mathematical technique known as boundary function method for singular perturbation system. In this system, the small parameter is an asymptotic variable, different from the independent variable. In general, the solutions of such equations exhibit multiscale phenomena. Singularly perturbed problems form a special class of problems containing a small parameter which may tend to zero. Many molecular biology processes can be quantitatively characterized by ordinary differential equations. Mathematical cell biology is a very active and fast growing interdisciplinary area in which mathematical concepts, techniques, and models are applied to a variety of problems in developmental medicine and bioengineering. Among the different modeling approaches, ordinary differential equations (ODE) are particularly important and have led to significant advances. Ordinary differential equations are used to model biological processes on various levels ranging from DNA molecules or biosynthesis phospholipids on the cellular level.

  14. Use of open-ended problems as the basis for the mathematical creativity growth disclosure of student

    NASA Astrophysics Data System (ADS)

    Suyitno, A.; Suyitno, H.; Rochmad; Dwijanto

    2018-03-01

    Mathematical creativity is the essence of learning in mathematics. However, mathematical creativity had not yet grown among students. Means there was a gap between needs and reality. This gap must be bridged through by scientific studies, and there were novelty findings, namely the discovery of stages to cultivate of Mathematical Creativity. The problem formulation: How to use of open-ended problems as the basis for the mathematical creativity growth disclosure of student? The goal was to use of open issues as the basis for the mathematical creativity growth disclosure of student. Research method with a qualitative approach. After data was collected then activity in data analysis, include data reduction, data presentation, data interpretation, and conclusion/verification. The results of the research: After the learning by applying the modification of RTTW learning model, then the students were trained to do the open-ended problems and by looking at the UTS and UAS values then qualitatively the results: (1) There was a significant increase of the student's final score. (2) The category of the growth of mathematical creativity of students, the Very Good there were three students, the Good there were six students, There were 17 students, and there were six students. The validation of these results was reinforced by interviews and triangulation. (3) Stage to cultivate mathematical creativity: lecturers should need to provide inputs on student work; Apply an appropriate learning model, and train students to work on the continuing problems.

  15. Reflective Modeling in Teacher Education.

    ERIC Educational Resources Information Center

    Shealy, Barry E.

    This paper describes mathematical modeling activities from a secondary mathematics teacher education course taken by fourth-year university students. Experiences with mathematical modeling are viewed as important in helping teachers develop a more intuitive understanding of mathematics, generate and evaluate mathematical interpretations, and…

  16. Primary School Pre-Service Mathematics Teachers' Views on Mathematical Modeling

    ERIC Educational Resources Information Center

    Karali, Diren; Durmus, Soner

    2015-01-01

    The current study aimed to identify the views of pre-service teachers, who attended a primary school mathematics teaching department but did not take mathematical modeling courses. The mathematical modeling activity used by the pre-service teachers was developed with regards to the modeling activities utilized by Lesh and Doerr (2003) in their…

  17. Mathematical model of bone drilling for virtual surgery system

    NASA Astrophysics Data System (ADS)

    Alaytsev, Innokentiy K.; Danilova, Tatyana V.; Manturov, Alexey O.; Mareev, Gleb O.; Mareev, Oleg V.

    2018-04-01

    The bone drilling is an essential part of surgeries in ENT and Dentistry. A proper training of drilling machine handling skills is impossible without proper modelling of the drilling process. Utilization of high precision methods like FEM is limited due to the requirement of 1000 Hz update rate for haptic feedback. The study presents a mathematical model of the drilling process that accounts the properties of materials, the geometry and the rotation rate of a burr to compute the removed material volume. The simplicity of the model allows for integrating it in the high-frequency haptic thread. The precision of the model is enough for a virtual surgery system targeted on the training of the basic surgery skills.

  18. A mathematical model for the deformation of the eyeball by an elastic band.

    PubMed

    Keeling, Stephen L; Propst, Georg; Stadler, Georg; Wackernagel, Werner

    2009-06-01

    In a certain kind of eye surgery, the human eyeball is deformed sustainably by the application of an elastic band. This article presents a mathematical model for the mechanics of the combined eye/band structure along with an algorithm to compute the model solutions. These predict the immediate and the lasting indentation of the eyeball. The model is derived from basic physical principles by minimizing a potential energy subject to a volume constraint. Assuming spherical symmetry, this leads to a two-point boundary-value problem for a non-linear second-order ordinary differential equation that describes the minimizing static equilibrium. By comparison with laboratory data, a preliminary validation of the model is given.

  19. Closed-form dynamics of a hexarot parallel manipulator by means of the principle of virtual work

    NASA Astrophysics Data System (ADS)

    Pedrammehr, Siamak; Nahavandi, Saeid; Abdi, Hamid

    2018-04-01

    In this research, a systematic approach to solving the inverse dynamics of hexarot manipulators is addressed using the methodology of virtual work. For the first time, a closed form of the mathematical formulation of the standard dynamic model is presented for this class of mechanisms. An efficient algorithm for solving this closed-form dynamic model of the mechanism is developed and it is used to simulate the dynamics of the system for different trajectories. Validation of the proposed model is performed using SimMechanics and it is shown that the results of the proposed mathematical model match with the results obtained by the SimMechanics model.

  20. A model for closing the inviscid form of the average-passage equation system

    NASA Technical Reports Server (NTRS)

    Adamczyk, J. J.; Mulac, R. A.; Celestina, M. L.

    1985-01-01

    A mathematical model is proposed for closing or mathematically completing the system of equations which describes the time average flow field through the blade passages of multistage turbomachinery. These equations referred to as the average passage equation system govern a conceptual model which has proven useful in turbomachinery aerodynamic design and analysis. The closure model is developed so as to insure a consistency between these equations and the axisymmetric through flow equations. The closure model was incorporated into a computer code for use in simulating the flow field about a high speed counter rotating propeller and a high speed fan stage. Results from these simulations are presented.

  1. Modeling malware propagation using a carrier compartment

    NASA Astrophysics Data System (ADS)

    Hernández Guillén, J. D.; Martín del Rey, A.

    2018-03-01

    The great majority of mathematical models proposed to simulate malware spreading are based on systems of ordinary differential equations. These are compartmental models where the devices are classified according to some types: susceptible, exposed, infectious, recovered, etc. As far as we know, there is not any model considering the special class of carrier devices. This type is constituted by the devices whose operative systems is not targeted by the malware (for example, iOS devices for Android malware). In this work a novel mathematical model considering this new compartment is considered. Its qualitative study is presented and a detailed analysis of the efficient control measures is shown by studying the basic reproductive number.

  2. Skolem and pessimism about proof in mathematics.

    PubMed

    Cohen, Paul J

    2005-10-15

    Attitudes towards formalization and proof have gone through large swings during the last 150 years. We sketch the development from Frege's first formalization, to the debates over intuitionism and other schools, through Hilbert's program and the decisive blow of the Gödel Incompleteness Theorem. A critical role is played by the Skolem-Lowenheim Theorem, which showed that no first-order axiom system can characterize a unique infinite model. Skolem himself regarded this as a body blow to the belief that mathematics can be reliably founded only on formal axiomatic systems. In a remarkably prescient paper, he even sketches the possibility of interesting new models for set theory itself, something later realized by the method of forcing. This is in contrast to Hilbert's belief that mathematics could resolve all its questions. We discuss the role of new axioms for set theory, questions in set theory itself, and their relevance for number theory. We then look in detail at what the methods of the predicate calculus, i.e. mathematical reasoning, really entail. The conclusion is that there is no reasonable basis for Hilbert's assumption. The vast majority of questions even in elementary number theory, of reasonable complexity, are beyond the reach of any such reasoning. Of course this cannot be proved and we present only plausibility arguments. The great success of mathematics comes from considering 'natural problems', those which are related to previous work and offer a good chance of being solved. The great glories of human reasoning, beginning with the Greek discovery of geometry, are in no way diminished by this pessimistic view. We end by wishing good health to present-day mathematics and the mathematics of many centuries to come.

  3. Binary logistic regression-Instrument for assessing museum indoor air impact on exhibits.

    PubMed

    Bucur, Elena; Danet, Andrei Florin; Lehr, Carol Blaziu; Lehr, Elena; Nita-Lazar, Mihai

    2017-04-01

    This paper presents a new way to assess the environmental impact on historical artifacts using binary logistic regression. The prediction of the impact on the exhibits during certain pollution scenarios (environmental impact) was calculated by a mathematical model based on the binary logistic regression; it allows the identification of those environmental parameters from a multitude of possible parameters with a significant impact on exhibitions and ranks them according to their severity effect. Air quality (NO 2 , SO 2 , O 3 and PM 2.5 ) and microclimate parameters (temperature, humidity) monitoring data from a case study conducted within exhibition and storage spaces of the Romanian National Aviation Museum Bucharest have been used for developing and validating the binary logistic regression method and the mathematical model. The logistic regression analysis was used on 794 data combinations (715 to develop of the model and 79 to validate it) by a Statistical Package for Social Sciences (SPSS 20.0). The results from the binary logistic regression analysis demonstrated that from six parameters taken into consideration, four of them present a significant effect upon exhibits in the following order: O 3 >PM 2.5 >NO 2 >humidity followed at a significant distance by the effects of SO 2 and temperature. The mathematical model, developed in this study, correctly predicted 95.1 % of the cumulated effect of the environmental parameters upon the exhibits. Moreover, this model could also be used in the decisional process regarding the preventive preservation measures that should be implemented within the exhibition space. The paper presents a new way to assess the environmental impact on historical artifacts using binary logistic regression. The mathematical model developed on the environmental parameters analyzed by the binary logistic regression method could be useful in a decision-making process establishing the best measures for pollution reduction and preventive preservation of exhibits.

  4. Biophysically Based Mathematical Modeling of Interstitial Cells of Cajal Slow Wave Activity Generated from a Discrete Unitary Potential Basis

    PubMed Central

    Faville, R.A.; Pullan, A.J.; Sanders, K.M.; Koh, S.D.; Lloyd, C.M.; Smith, N.P.

    2009-01-01

    Abstract Spontaneously rhythmic pacemaker activity produced by interstitial cells of Cajal (ICC) is the result of the entrainment of unitary potential depolarizations generated at intracellular sites termed pacemaker units. In this study, we present a mathematical modeling framework that quantitatively represents the transmembrane ion flows and intracellular Ca2+ dynamics from a single ICC operating over the physiological membrane potential range. The mathematical model presented here extends our recently developed biophysically based pacemaker unit modeling framework by including mechanisms necessary for coordinating unitary potential events, such as a T-Type Ca2+ current, Vm-dependent K+ currents, and global Ca2+ diffusion. Model simulations produce spontaneously rhythmic slow wave depolarizations with an amplitude of 65 mV at a frequency of 17.4 cpm. Our model predicts that activity at the spatial scale of the pacemaker unit is fundamental for ICC slow wave generation, and Ca2+ influx from activation of the T-Type Ca2+ current is required for unitary potential entrainment. These results suggest that intracellular Ca2+ levels, particularly in the region local to the mitochondria and endoplasmic reticulum, significantly influence pacing frequency and synchronization of pacemaker unit discharge. Moreover, numerical investigations show that our ICC model is capable of qualitatively replicating a wide range of experimental observations. PMID:19527643

  5. Modeling of composite coupling technology for oil-gas pipeline section resource-saving repair

    NASA Astrophysics Data System (ADS)

    Donkova, Irina; Yakubovskiy, Yuriy; Kruglov, Mikhail

    2017-10-01

    The article presents a variant of modeling and calculation of a main pipeline repair section with a composite coupling installation. This section is presented in a shape of a composite cylindrical shell. The aim of this work is mathematical modeling and study of main pipeline reconstruction section stress-strain state (SSS). There has been given a description of a structure deformation mathematical model. Based on physical relations of elasticity, integral characteristics of rigidity for each layer of a two-layer pipe section have been obtained. With the help of the systems of forces and moments which affect the layers differential equations for the first and second layer (pipeline and coupling) have been obtained. The study of the SSS has been conducted using the statements and hypotheses of the composite structures deformation theory with consideration of interlayer joint stresses. The relations to describe the work of the joint have been stated. Boundary conditions for each layer have been formulated. To describe the deformation of the composite coupling with consideration of the composite cylindrical shells theory a mathematical model in the form of a system of differential equations in displacements and boundary conditions has been obtained. Calculation of a two-layer cylindrical shell under the action of an axisymmetric load has been accomplished.

  6. The implementation of multiple intelligences based teaching model to improve mathematical problem solving ability for student of junior high school

    NASA Astrophysics Data System (ADS)

    Fasni, Nurli; Fatimah, Siti; Yulanda, Syerli

    2017-05-01

    This research aims to achieve some purposes such as: to know whether mathematical problem solving ability of students who have learned mathematics using Multiple Intelligences based teaching model is higher than the student who have learned mathematics using cooperative learning; to know the improvement of the mathematical problem solving ability of the student who have learned mathematics using Multiple Intelligences based teaching model., to know the improvement of the mathematical problem solving ability of the student who have learned mathematics using cooperative learning; to know the attitude of the students to Multiple Intelligences based teaching model. The method employed here is quasi-experiment which is controlled by pre-test and post-test. The population of this research is all of VII grade in SMP Negeri 14 Bandung even-term 2013/2014, later on two classes of it were taken for the samples of this research. A class was taught using Multiple Intelligences based teaching model and the other one was taught using cooperative learning. The data of this research were gotten from the test in mathematical problem solving, scale questionnaire of the student attitudes, and observation. The results show the mathematical problem solving of the students who have learned mathematics using Multiple Intelligences based teaching model learning is higher than the student who have learned mathematics using cooperative learning, the mathematical problem solving ability of the student who have learned mathematics using cooperative learning and Multiple Intelligences based teaching model are in intermediate level, and the students showed the positive attitude in learning mathematics using Multiple Intelligences based teaching model. As for the recommendation for next author, Multiple Intelligences based teaching model can be tested on other subject and other ability.

  7. Using Mathematics, Mathematical Applications, Mathematical Modelling, and Mathematical Literacy: A Theoretical Study

    ERIC Educational Resources Information Center

    Mumcu, Hayal Yavuz

    2016-01-01

    The purpose of this theoretical study is to explore the relationships between the concepts of using mathematics in the daily life, mathematical applications, mathematical modelling, and mathematical literacy. As these concepts are generally taken as independent concepts in the related literature, they are confused with each other and it becomes…

  8. On dynamics of integrate-and-fire neural networks with conductance based synapses.

    PubMed

    Cessac, Bruno; Viéville, Thierry

    2008-01-01

    We present a mathematical analysis of networks with integrate-and-fire (IF) neurons with conductance based synapses. Taking into account the realistic fact that the spike time is only known within some finite precision, we propose a model where spikes are effective at times multiple of a characteristic time scale delta, where delta can be arbitrary small (in particular, well beyond the numerical precision). We make a complete mathematical characterization of the model-dynamics and obtain the following results. The asymptotic dynamics is composed by finitely many stable periodic orbits, whose number and period can be arbitrary large and can diverge in a region of the synaptic weights space, traditionally called the "edge of chaos", a notion mathematically well defined in the present paper. Furthermore, except at the edge of chaos, there is a one-to-one correspondence between the membrane potential trajectories and the raster plot. This shows that the neural code is entirely "in the spikes" in this case. As a key tool, we introduce an order parameter, easy to compute numerically, and closely related to a natural notion of entropy, providing a relevant characterization of the computational capabilities of the network. This allows us to compare the computational capabilities of leaky and IF models and conductance based models. The present study considers networks with constant input, and without time-dependent plasticity, but the framework has been designed for both extensions.

  9. Modeling Flow in Porous Media with Double Porosity/Permeability.

    NASA Astrophysics Data System (ADS)

    Seyed Joodat, S. H.; Nakshatrala, K. B.; Ballarini, R.

    2016-12-01

    Although several continuum models are available to study the flow of fluids in porous media with two pore-networks [1], they lack a firm theoretical basis. In this poster presentation, we will present a mathematical model with firm thermodynamic basis and a robust computational framework for studying flow in porous media that exhibit double porosity/permeability. The mathematical model will be derived by appealing to the maximization of rate of dissipation hypothesis, which ensures that the model is in accord with the second law of thermodynamics. We will also present important properties that the solutions under the model satisfy, along with an analytical solution procedure based on the Green's function method. On the computational front, a stabilized mixed finite element formulation will be derived based on the variational multi-scale formalism. The equal-order interpolation, which is computationally the most convenient, is stable under this formulation. The performance of this formulation will be demonstrated using patch tests, numerical convergence study, and representative problems. It will be shown that the pressure and velocity profiles under the double porosity/permeability model are qualitatively and quantitatively different from the corresponding ones under the classical Darcy equations. Finally, it will be illustrated that the surface pore-structure is not sufficient in characterizing the flow through a complex porous medium, which pitches a case for using advanced characterization tools like micro-CT. References [1] G. I. Barenblatt, I. P. Zheltov, and I. N. Kochina, "Basic concepts in the theory of seepage of homogeneous liquids in fissured rocks [strata]," Journal of Applied Mathematics and Mechanics, vol. 24, pp. 1286-1303, 1960.

  10. Pre-Service Teachers' Developing Conceptions about the Nature and Pedagogy of Mathematical Modeling in the Context of a Mathematical Modeling Course

    ERIC Educational Resources Information Center

    Cetinkaya, Bulent; Kertil, Mahmut; Erbas, Ayhan Kursat; Korkmaz, Himmet; Alacaci, Cengiz; Cakiroglu, Erdinc

    2016-01-01

    Adopting a multitiered design-based research perspective, this study examines pre-service secondary mathematics teachers' developing conceptions about (a) the nature of mathematical modeling in simulations of "real life" problem solving, and (b) pedagogical principles and strategies needed to teach mathematics through modeling. Unlike…

  11. Evolution of Mathematics Teachers' Pedagogical Knowledge When They Are Teaching through Modeling

    ERIC Educational Resources Information Center

    Aydogan Yenmez, Arzu; Erbas, Ayhan Kursat; Alacaci, Cengiz; Cakiroglu, Erdinc; Cetinkaya, Bulent

    2017-01-01

    Use of mathematical modeling in mathematics education has been receiving significant attention as a way to develop students' mathematical knowledge and skills. As effective use of modeling in classes depends on the competencies of teachers we need to know more about the nature of teachers' knowledge to use modeling in mathematics education and how…

  12. Mathematical Modeling in Science: Using Spreadsheets to Create Mathematical Models and Address Scientific Inquiry

    ERIC Educational Resources Information Center

    Horton, Robert M.; Leonard, William H.

    2005-01-01

    In science, inquiry is used as students explore important and interesting questions concerning the world around them. In mathematics, one contemporary inquiry approach is to create models that describe real phenomena. Creating mathematical models using spreadsheets can help students learn at deep levels in both science and mathematics, and give…

  13. PREFACE: 3rd International Conference on Mathematical Modeling in Physical Sciences (IC-MSQUARE 2014)

    NASA Astrophysics Data System (ADS)

    2015-01-01

    The third International Conference on Mathematical Modeling in Physical Sciences (IC-MSQUARE) took place at Madrid, Spain, from Thursday 28 to Sunday 31 August 2014. The Conference was attended by more than 200 participants and hosted about 350 oral, poster, and virtual presentations. More than 600 pre-registered authors were also counted. The third IC-MSQUARE consisted of different and diverging workshops and thus covered various research fields where Mathematical Modeling is used, such as Theoretical/Mathematical Physics, Neutrino Physics, Non-Integrable Systems, Dynamical Systems, Computational Nanoscience, Biological Physics, Computational Biomechanics, Complex Networks, Stochastic Modeling, Fractional Statistics, DNA Dynamics, Macroeconomics etc. The scientific program was rather heavy since after the Keynote and Invited Talks in the morning, three parallel oral sessions and one poster session were running every day. However, according to all attendees, the program was excellent with high level of talks and the scientific environment was fruitful, thus all attendees had a creative time. We would like to thank the Keynote Speaker and the Invited Speakers for their significant contribution to IC-MSQUARE. We also would like to thank the Members of the International Advisory and Scientific Committees as well as the Members of the Organizing Committee.

  14. PREFACE: 4th International Conference on Mathematical Modeling in Physical Sciences (IC-MSquare2015)

    NASA Astrophysics Data System (ADS)

    Vlachos, Dimitrios; Vagenas, Elias C.

    2015-09-01

    The 4th International Conference on Mathematical Modeling in Physical Sciences (IC-MSQUARE) took place in Mykonos, Greece, from Friday 5th June to Monday 8th June 2015. The Conference was attended by more than 150 participants and hosted about 200 oral, poster, and virtual presentations. There were more than 600 pre-registered authors. The 4th IC-MSQUARE consisted of different and diverging workshops and thus covered various research fields where Mathematical Modeling is used, such as Theoretical/Mathematical Physics, Neutrino Physics, Non-Integrable Systems, Dynamical Systems, Computational Nanoscience, Biological Physics, Computational Biomechanics, Complex Networks, Stochastic Modeling, Fractional Statistics, DNA Dynamics, Macroeconomics etc. The scientific program was rather intense as after the Keynote and Invited Talks in the morning, three parallel oral and one poster session were running every day. However, according to all attendees, the program was excellent with a high quality of talks creating an innovative and productive scientific environment for all attendees. We would like to thank the Keynote Speaker and the Invited Speakers for their significant contribution to IC-MSQUARE. We also would like to thank the Members of the International Advisory and Scientific Committees as well as the Members of the Organizing Committee.

  15. QR-STEM: Energy and Environment as a Context for Improving QR and STEM Understandings of 6-12 Grade Teachers II. The Quantitative Reasoning

    NASA Astrophysics Data System (ADS)

    Mayes, R.; Lyford, M. E.; Myers, J. D.

    2009-12-01

    The Quantitative Reasoning in STEM (QR STEM) project is a state level Mathematics and Science Partnership Project (MSP) with a focus on the mathematics and statistics that underlies the understanding of complex global scientific issues. This session is a companion session to the QR STEM: The Science presentation. The focus of this session is the quantitative reasoning aspects of the project. As students move from understandings that range from local to global in perspective on issues of energy and environment, there is a significant increase in the need for mathematical and statistical conceptual understanding. These understandings must be accessible to the students within the scientific context, requiring the special understandings that are endemic within quantitative reasoning. The QR STEM project brings together interdisciplinary teams of higher education faculty and middle/high school teachers to explore complex problems in energy and environment. The disciplines include life sciences, physics, chemistry, earth science, statistics, and mathematics. These interdisciplinary teams develop open ended performance tasks to implement in the classroom, based on scientific concepts that underpin energy and environment. Quantitative reasoning is broken down into three components: Quantitative Literacy, Quantitative Interpretation, and Quantitative Modeling. Quantitative Literacy is composed of arithmetic concepts such as proportional reasoning, numeracy, and descriptive statistics. Quantitative Interpretation includes algebraic and geometric concepts that underlie the ability to interpret a model of natural phenomena which is provided for the student. This model may be a table, graph, or equation from which the student is to make predictions or identify trends, or from which they would use statistics to explore correlations or patterns in data. Quantitative modeling is the ability to develop the model from data, including the ability to test hypothesis using statistical procedures. We use the term model very broadly, so it includes visual models such as box models, as well as best fit equation models and hypothesis testing. One of the powerful outcomes of the project is the conversation which takes place between science teachers and mathematics teachers. First they realize that though they are teaching concepts that cross their disciplines, the barrier of scientific language within their subjects restricts students from applying the concepts across subjects. Second the mathematics teachers discover the context of science as a means of providing real world situations that engage students in the utility of mathematics as a tool for solving problems. Third the science teachers discover the barrier to understanding science that is presented by poor quantitative reasoning ability. Finally the students are engaged in exploring energy and environment in a manner which exposes the importance of seeing a problem from multiple interdisciplinary perspectives. The outcome is a democratic citizen capable of making informed decisions, and perhaps a future scientist.

  16. Understanding immunology via engineering design: the role of mathematical prototyping.

    PubMed

    Klinke, David J; Wang, Qing

    2012-01-01

    A major challenge in immunology is how to translate data into knowledge given the inherent complexity and dynamics of human physiology. Both the physiology and engineering communities have rich histories in applying computational approaches to translate data obtained from complex systems into knowledge of system behavior. However, there are some differences in how disciplines approach problems. By referring to mathematical models as mathematical prototypes, we aim to highlight aspects related to the process (i.e., prototyping) rather than the product (i.e., the model). The objective of this paper is to review how two related engineering concepts, specifically prototyping and "fitness for use," can be applied to overcome the pressing challenge in translating data into improved knowledge of basic immunology that can be used to improve therapies for disease. These concepts are illustrated using two immunology-related examples. The prototypes presented focus on the beta cell mass at the onset of type 1 diabetes and the dynamics of dendritic cells in the lung. This paper is intended to illustrate some of the nuances associated with applying mathematical modeling to improve understanding of the dynamics of disease progression in humans.

  17. Conditions for duality between fluxes and concentrations in biochemical networks

    PubMed Central

    Fleming, Ronan M.T.; Vlassis, Nikos; Thiele, Ines; Saunders, Michael A.

    2016-01-01

    Mathematical and computational modelling of biochemical networks is often done in terms of either the concentrations of molecular species or the fluxes of biochemical reactions. When is mathematical modelling from either perspective equivalent to the other? Mathematical duality translates concepts, theorems or mathematical structures into other concepts, theorems or structures, in a one-to-one manner. We present a novel stoichiometric condition that is necessary and sufficient for duality between unidirectional fluxes and concentrations. Our numerical experiments, with computational models derived from a range of genome-scale biochemical networks, suggest that this flux-concentration duality is a pervasive property of biochemical networks. We also provide a combinatorial characterisation that is sufficient to ensure flux-concentration duality. The condition prescribes that, for every two disjoint sets of molecular species, there is at least one reaction complex that involves species from only one of the two sets. When unidirectional fluxes and molecular species concentrations are dual vectors, this implies that the behaviour of the corresponding biochemical network can be described entirely in terms of either concentrations or unidirectional fluxes. PMID:27345817

  18. Conditions for duality between fluxes and concentrations in biochemical networks

    DOE PAGES

    Fleming, Ronan M. T.; Vlassis, Nikos; Thiele, Ines; ...

    2016-06-23

    Mathematical and computational modelling of biochemical networks is often done in terms of either the concentrations of molecular species or the fluxes of biochemical reactions. When is mathematical modelling from either perspective equivalent to the other? Mathematical duality translates concepts, theorems or mathematical structures into other concepts, theorems or structures, in a one-to-one manner. We present a novel stoichiometric condition that is necessary and sufficient for duality between unidirectional fluxes and concentrations. Our numerical experiments, with computational models derived from a range of genome-scale biochemical networks, suggest that this flux-concentration duality is a pervasive property of biochemical networks. We alsomore » provide a combinatorial characterisation that is sufficient to ensure flux-concentration duality.The condition prescribes that, for every two disjoint sets of molecular species, there is at least one reaction complex that involves species from only one of the two sets. When unidirectional fluxes and molecular species concentrations are dual vectors, this implies that the behaviour of the corresponding biochemical network can be described entirely in terms of either concentrations or unidirectional fluxes« less

  19. Conditions for duality between fluxes and concentrations in biochemical networks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fleming, Ronan M. T.; Vlassis, Nikos; Thiele, Ines

    Mathematical and computational modelling of biochemical networks is often done in terms of either the concentrations of molecular species or the fluxes of biochemical reactions. When is mathematical modelling from either perspective equivalent to the other? Mathematical duality translates concepts, theorems or mathematical structures into other concepts, theorems or structures, in a one-to-one manner. We present a novel stoichiometric condition that is necessary and sufficient for duality between unidirectional fluxes and concentrations. Our numerical experiments, with computational models derived from a range of genome-scale biochemical networks, suggest that this flux-concentration duality is a pervasive property of biochemical networks. We alsomore » provide a combinatorial characterisation that is sufficient to ensure flux-concentration duality.The condition prescribes that, for every two disjoint sets of molecular species, there is at least one reaction complex that involves species from only one of the two sets. When unidirectional fluxes and molecular species concentrations are dual vectors, this implies that the behaviour of the corresponding biochemical network can be described entirely in terms of either concentrations or unidirectional fluxes« less

  20. Mathematical models of bipolar disorder

    NASA Astrophysics Data System (ADS)

    Daugherty, Darryl; Roque-Urrea, Tairi; Urrea-Roque, John; Troyer, Jessica; Wirkus, Stephen; Porter, Mason A.

    2009-07-01

    We use limit cycle oscillators to model bipolar II disorder, which is characterized by alternating hypomanic and depressive episodes and afflicts about 1% of the United States adult population. We consider two non-linear oscillator models of a single bipolar patient. In both frameworks, we begin with an untreated individual and examine the mathematical effects and resulting biological consequences of treatment. We also briefly consider the dynamics of interacting bipolar II individuals using weakly-coupled, weakly-damped harmonic oscillators. We discuss how the proposed models can be used as a framework for refined models that incorporate additional biological data. We conclude with a discussion of possible generalizations of our work, as there are several biologically-motivated extensions that can be readily incorporated into the series of models presented here.

  1. [Influence of sample surface roughness on mathematical model of NIR quantitative analysis of wood density].

    PubMed

    Huang, An-Min; Fei, Ben-Hua; Jiang, Ze-Hui; Hse, Chung-Yun

    2007-09-01

    Near infrared spectroscopy is widely used as a quantitative method, and the main multivariate techniques consist of regression methods used to build prediction models, however, the accuracy of analysis results will be affected by many factors. In the present paper, the influence of different sample roughness on the mathematical model of NIR quantitative analysis of wood density was studied. The result of experiments showed that if the roughness of predicted samples was consistent with that of calibrated samples, the result was good, otherwise the error would be much higher. The roughness-mixed model was more flexible and adaptable to different sample roughness. The prediction ability of the roughness-mixed model was much better than that of the single-roughness model.

  2. Understanding Prospective Teachers' Mathematical Modeling Processes in the Context of a Mathematical Modeling Course

    ERIC Educational Resources Information Center

    Zeytun, Aysel Sen; Cetinkaya, Bulent; Erbas, Ayhan Kursat

    2017-01-01

    This paper investigates how prospective teachers develop mathematical models while they engage in modeling tasks. The study was conducted in an undergraduate elective course aiming to improve prospective teachers' mathematical modeling abilities, while enhancing their pedagogical knowledge for the integrating of modeling tasks into their future…

  3. Design of a Model-Based Online Management Information System for Interlibrary Loan Networks.

    ERIC Educational Resources Information Center

    Rouse, Sandra H.; Rouse, William B.

    1979-01-01

    Discusses the design of a model-based management information system in terms of mathematical/statistical, information processing, and human factors issues and presents a prototype system for interlibrary loan networks. (Author/CWM)

  4. Risk Assessment for Toxic Air Pollutants: A Citizen's Guide

    MedlinePlus

    ... from the source(s). Engineers use either monitors or computer models to estimate the amount of pollutant released ... measure how much of the pollutant is present. Computer models use mathematical equations that represent the processes ...

  5. Building Your Own Regression Model

    ERIC Educational Resources Information Center

    Horton, Robert, M.; Phillips, Vicki; Kenelly, John

    2004-01-01

    Spreadsheets to explore regression with an algebra 2 class in a medium-sized rural high school are presented. The use of spreadsheets can help students develop sophisticated understanding of mathematical models and use them to describe real-world phenomena.

  6. Flow and transport due to natural convection in a galvanic cell. 1: Development of a mathematical model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Siu, S.; Evans, J.W.

    1997-08-01

    In many electrochemical cells, the flow of electrolyte has an influence on cell behavior and this investigation concerns a cell (a zinc-air cell) where that flow occurred through natural convection. The zinc was present in the form of a bed of particles, connected at its top and bottom with channels forming reservoirs of electrolyte. Dissolution of the zinc caused density differences between electrolyte in the bed interstices and that in the reservoir. In Part 1 of this two-part paper, a mathematical model for this cell is developed. The model employs the well-known Newman/Tobias description of a porous electrode and treatsmore » flow through the bed using the Blake-Kozeny equation. A fourth-order Lax-Wendroff algorithm, thought to be original, is used to solve the convective diffusion equation within the model. Sample computed results are presented.« less

  7. Designing a mathematical model for integrating dynamic cellular manufacturing into supply chain system

    NASA Astrophysics Data System (ADS)

    Aalaei, Amin; Davoudpour, Hamid

    2012-11-01

    This article presents designing a new mathematical model for integrating dynamic cellular manufacturing into supply chain system with an extensive coverage of important manufacturing features consideration of multiple plants location, multi-markets allocation, multi-period planning horizons with demand and part mix variation, machine capacity, and the main constraints are demand of markets satisfaction in each period, machine availability, machine time-capacity, worker assignment, available time of worker, production volume for each plant and the amounts allocated to each market. The aim of the proposed model is to minimize holding and outsourcing costs, inter-cell material handling cost, external transportation cost, procurement & maintenance and overhead cost of machines, setup cost, reconfiguration cost of machines installation and removal, hiring, firing and salary worker costs. Aimed to prove the potential benefits of such a design, presented an example is shown using a proposed model.

  8. Forecasting characteristics of flood effects

    NASA Astrophysics Data System (ADS)

    Khamutova, M. V.; Rezchikov, A. F.; Kushnikov, V. A.; Ivaschenko, V. A.; Bogomolov, A. S.; Filimonyuk, L. Yu; Dolinina, O. N.; Kushnikova, E. V.; Shulga, T. E.; Tverdokhlebov, V. A.; Fominykh, D. S.

    2018-05-01

    The article presents the development of a mathematical model of the system dynamics. Mathematical model allows forecasting the characteristics of flood effects. Model is based on a causal diagram and is presented by a system of nonlinear differential equations. Simulated characteristics are the nodes of the diagram, and edges define the functional relationships between them. The numerical solution of the system of equations using the Runge-Kutta method was obtained. Computer experiments to determine the characteristics on different time interval have been made and results of experiments have been compared with real data of real flood. The obtained results make it possible to assert that the developed model is valid. The results of study are useful in development of an information system for the operating and dispatching staff of the Ministry of the Russian Federation for Civil Defence, Emergencies and Elimination of Consequences of Natural Disasters (EMERCOM).

  9. Introducing Modeling Transition Diagrams as a Tool to Connect Mathematical Modeling to Mathematical Thinking

    ERIC Educational Resources Information Center

    Czocher, Jennifer A.

    2016-01-01

    This study contributes a methodological tool to reconstruct the cognitive processes and mathematical activities carried out by mathematical modelers. Represented as Modeling Transition Diagrams (MTDs), individual modeling routes were constructed for four engineering undergraduate students. Findings stress the importance and limitations of using…

  10. An Experimental Approach to Mathematical Modeling in Biology

    ERIC Educational Resources Information Center

    Ledder, Glenn

    2008-01-01

    The simplest age-structured population models update a population vector via multiplication by a matrix. These linear models offer an opportunity to introduce mathematical modeling to students of limited mathematical sophistication and background. We begin with a detailed discussion of mathematical modeling, particularly in a biological context.…

  11. Mathematical Modeling with Middle School Students: The Robot Art Model-Eliciting Activity

    ERIC Educational Resources Information Center

    Stohlmann, Micah S.

    2017-01-01

    Internationally mathematical modeling is garnering more attention for the benefits associated with it. Mathematical modeling can develop students' communication skills and the ability to demonstrate understanding through different representations. With the increased attention on mathematical modeling, there is a need for more curricula to be…

  12. Changing Pre-Service Mathematics Teachers' Beliefs about Using Computers for Teaching and Learning Mathematics: The Effect of Three Different Models

    ERIC Educational Resources Information Center

    Karatas, Ilhan

    2014-01-01

    This study examines the effect of three different computer integration models on pre-service mathematics teachers' beliefs about using computers in mathematics education. Participants included 104 pre-service mathematics teachers (36 second-year students in the Computer Oriented Model group, 35 fourth-year students in the Integrated Model (IM)…

  13. Incorporating individual health-protective decisions into disease transmission models: a mathematical framework.

    PubMed

    Durham, David P; Casman, Elizabeth A

    2012-03-07

    It is anticipated that the next generation of computational epidemic models will simulate both infectious disease transmission and dynamic human behaviour change. Individual agents within a simulation will not only infect one another, but will also have situational awareness and a decision algorithm that enables them to modify their behaviour. This paper develops such a model of behavioural response, presenting a mathematical interpretation of a well-known psychological model of individual decision making, the health belief model, suitable for incorporation within an agent-based disease-transmission model. We formalize the health belief model and demonstrate its application in modelling the prevalence of facemask use observed over the course of the 2003 Hong Kong SARS epidemic, a well-documented example of behaviour change in response to a disease outbreak.

  14. Incorporating individual health-protective decisions into disease transmission models: a mathematical framework

    PubMed Central

    Durham, David P.; Casman, Elizabeth A.

    2012-01-01

    It is anticipated that the next generation of computational epidemic models will simulate both infectious disease transmission and dynamic human behaviour change. Individual agents within a simulation will not only infect one another, but will also have situational awareness and a decision algorithm that enables them to modify their behaviour. This paper develops such a model of behavioural response, presenting a mathematical interpretation of a well-known psychological model of individual decision making, the health belief model, suitable for incorporation within an agent-based disease-transmission model. We formalize the health belief model and demonstrate its application in modelling the prevalence of facemask use observed over the course of the 2003 Hong Kong SARS epidemic, a well-documented example of behaviour change in response to a disease outbreak. PMID:21775324

  15. Mathematical modeling and simulation of a thermal system

    NASA Astrophysics Data System (ADS)

    Toropoc, Mirela; Gavrila, Camelia; Frunzulica, Rodica; Toma, Petrica D.

    2016-12-01

    The aim of the present paper is the conception of a mathematical model and simulation of a system formed by a heatexchanger for domestic hot water preparation, a storage tank for hot water and a radiator, starting from the mathematical equations describing this system and developed using Scilab-Xcos program. The model helps to determine the evolution in time for the hot water temperature, for the return temperature in the primary circuit of the heat exchanger, for the supply temperature in the secondary circuit, the thermal power for heating and for hot water preparation to the consumer respectively. In heating systems, heat-exchangers have an important role and their performances influence the energy efficiency of the systems. In the meantime, it is very important to follow the behavior of such systems in dynamic regimes. Scilab-Xcos program can be utilized to follow the important parameters of the systems in different functioning scenarios.

  16. Mathematic model of regional economy development by the final result of labor resources

    NASA Astrophysics Data System (ADS)

    Zaitseva, Irina; Malafeev, Oleg; Strekopytov, Sergei; Bondarenko, Galina; Lovyannikov, Denis

    2018-04-01

    This article presents the mathematic model of regional economy development based on the result of labor resources. The solution of a region development-planning problem is considered for the period of long-lasting planning taking into account the beginning and the end of the planned period. The challenge is to find the distribution of investments in the main and additional branches of the regional economy, which will provide simultaneous transaction of all major sectors of the regional economy from the given condition to the predetermined final state.

  17. Mathematical modeling of heat transfer problems in the permafrost

    NASA Astrophysics Data System (ADS)

    Gornov, V. F.; Stepanov, S. P.; Vasilyeva, M. V.; Vasilyev, V. I.

    2014-11-01

    In this work we present results of numerical simulation of three-dimensional temperature fields in soils for various applied problems: the railway line in the conditions of permafrost for different geometries, the horizontal tunnel underground storage and greenhouses of various designs in the Far North. Mathematical model of the process is described by a nonstationary heat equation with phase transitions of pore water. The numerical realization of the problem is based on the finite element method using a library of scientific computing FEniCS. For numerical calculations we use high-performance computing systems.

  18. Systems Biology Approach and Mathematical Modeling for Analyzing Phase-Space Switch During Epithelial-Mesenchymal Transition.

    PubMed

    Simeoni, Chiara; Dinicola, Simona; Cucina, Alessandra; Mascia, Corrado; Bizzarri, Mariano

    2018-01-01

    In this report, we aim at presenting a viable strategy for the study of Epithelial-Mesenchymal Transition (EMT) and its opposite Mesenchymal-Epithelial Transition (MET) by means of a Systems Biology approach combined with a suitable Mathematical Modeling analysis. Precisely, it is shown how the presence of a metastable state, that is identified at a mesoscopic level of description, is crucial for making possible the appearance of a phase transition mechanism in the framework of fast-slow dynamics for Ordinary Differential Equations (ODEs).

  19. Numerical simulation of the coaxial magneto-plasma accelerator and non-axisymmetric radio frequency discharge

    NASA Astrophysics Data System (ADS)

    Kuzenov, V. V.; Ryzhkov, S. V.; Frolko, P. A.

    2017-05-01

    The paper presents the results of mathematical modeling of physical processes in electronic devices such as helicon discharge and coaxial pulsed plasma thruster. A mathematical model of coaxial magneto-plasma accelerator (with a preionization helicon discharge), which allows estimating the transformation of one form of energy to another, as well as to evaluate the level of the contribution of different types of energy, the increase in mass of the accelerated plasmoid in the process of changing the speed. Main plasma parameters with experimental data were compared.

  20. International note: Prediction of mathematics work ethic and performance from behavioral, normative, and control beliefs among Qatari adolescents.

    PubMed

    Areepattamannil, Shaljan; Abdelfattah, Faisal; Mahasneh, Randa Ali; Khine, Myint Swe; Welch, Anita G; Melkonian, Michael; Al Nuaimi, Samira Ahmed

    2016-01-01

    Over half-a-million adolescents take part in each cycle of the Program for International Student Assessment (PISA). Yet often, researchers and policy makers across the globe tend to focus their attention primarily on the academic trajectories of adolescents hailing from highly successful education systems. Hence, a vast majority of the adolescent population who regionally and globally constitute the 'long tail of underachievement' often remain unnoticed and underrepresented in the growing literature on adolescents' academic trajectories. The present study, therefore, explored the relations of dispositions toward mathematics, subjective norms in mathematics, and perceived control of success in mathematics to mathematics work ethic as well as mathematics performance; and the mediational role of mathematics work ethic in the association between dispositional, normative, and control beliefs and mathematics performance among adolescents in one of the lowest performing education systems, Qatar. Structural equation modeling (SEM) analyses revealed that Qatari adolescents' dispositional, normative, and control beliefs about mathematics were significantly associated with their mathematics work ethic and mathematics performance, and mathematics work ethic significantly mediated the relationship between dispositional, normative, and control beliefs about mathematics and mathematics performance. However, multi-group SEM analyses indicated that these relationships were not invariant across the gender and the SES groups. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  1. Mathematical Modeling: A Structured Process

    ERIC Educational Resources Information Center

    Anhalt, Cynthia Oropesa; Cortez, Ricardo

    2015-01-01

    Mathematical modeling, in which students use mathematics to explain or interpret physical, social, or scientific phenomena, is an essential component of the high school curriculum. The Common Core State Standards for Mathematics (CCSSM) classify modeling as a K-12 standard for mathematical practice and as a conceptual category for high school…

  2. Mathematical Models of Elementary Mathematics Learning and Performance. Final Report.

    ERIC Educational Resources Information Center

    Suppes, Patrick

    This project was concerned with the development of mathematical models of elementary mathematics learning and performance. Probabilistic finite automata and register machines with a finite number of registers were developed as models and extensively tested with data arising from the elementary-mathematics strand curriculum developed by the…

  3. To Assess Students' Attitudes, Skills and Competencies in Mathematical Modeling

    ERIC Educational Resources Information Center

    Lingefjard, Thomas; Holmquist, Mikael

    2005-01-01

    Peer-to-peer assessment, take-home exams and a mathematical modeling survey were used to monitor and assess students' attitudes, skills and competencies in mathematical modeling. The students were all in a secondary mathematics, teacher education program with a comprehensive amount of mathematics studies behind them. Findings indicate that…

  4. Mathematical Modeling in the Undergraduate Curriculum

    ERIC Educational Resources Information Center

    Toews, Carl

    2012-01-01

    Mathematical modeling occupies an unusual space in the undergraduate mathematics curriculum: typically an "advanced" course, it nonetheless has little to do with formal proof, the usual hallmark of advanced mathematics. Mathematics departments are thus forced to decide what role they want the modeling course to play, both as a component of the…

  5. Teachers' Conceptions of Mathematical Modeling

    ERIC Educational Resources Information Center

    Gould, Heather

    2013-01-01

    The release of the "Common Core State Standards for Mathematics" in 2010 resulted in a new focus on mathematical modeling in United States curricula. Mathematical modeling represents a way of doing and understanding mathematics new to most teachers. The purpose of this study was to determine the conceptions and misconceptions held by…

  6. Experimentation of cooperative learning model Numbered Heads Together (NHT) type by concept maps and Teams Games Tournament (TGT) by concept maps in terms of students logical mathematics intellegences

    NASA Astrophysics Data System (ADS)

    Irawan, Adi; Mardiyana; Retno Sari Saputro, Dewi

    2017-06-01

    This research is aimed to find out the effect of learning model towards learning achievement in terms of students’ logical mathematics intelligences. The learning models that were compared were NHT by Concept Maps, TGT by Concept Maps, and Direct Learning model. This research was pseudo experimental by factorial design 3×3. The population of this research was all of the students of class XI Natural Sciences of Senior High School in all regency of Karanganyar in academic year 2016/2017. The conclusions of this research were: 1) the students’ achievements with NHT learning model by Concept Maps were better than students’ achievements with TGT model by Concept Maps and Direct Learning model. The students’ achievements with TGT model by Concept Maps were better than the students’ achievements with Direct Learning model. 2) The students’ achievements that exposed high logical mathematics intelligences were better than students’ medium and low logical mathematics intelligences. The students’ achievements that exposed medium logical mathematics intelligences were better than the students’ low logical mathematics intelligences. 3) Each of student logical mathematics intelligences with NHT learning model by Concept Maps has better achievement than students with TGT learning model by Concept Maps, students with NHT learning model by Concept Maps have better achievement than students with the direct learning model, and the students with TGT by Concept Maps learning model have better achievement than students with Direct Learning model. 4) Each of learning model, students who have logical mathematics intelligences have better achievement then students who have medium logical mathematics intelligences, and students who have medium logical mathematics intelligences have better achievement than students who have low logical mathematics intelligences.

  7. Modes of Modelling Assessment--A Literature Review

    ERIC Educational Resources Information Center

    Frejd, Peter

    2013-01-01

    This paper presents a critical review of literature investigating assessment of mathematical modelling. Written tests, projects, hands-on tests, portfolio and contests are modes of modelling assessment identified in this study. The written tests found in the reviewed papers draw on an atomistic view on modelling competencies, whereas projects are…

  8. The Rangeland Hydrology and Erosion Model: A dynamic approach for predicting soil loss on rangelands

    USDA-ARS?s Scientific Manuscript database

    In this study we present the improved Rangeland Hydrology and Erosion Model (RHEM V2.3), a process-based erosion prediction tool specific for rangeland application. The article provides the mathematical formulation of the model and parameter estimation equations. Model performance is assessed agains...

  9. Teaching Population Ecology Modeling by Means of the Hewlett-Packard 9100A.

    ERIC Educational Resources Information Center

    Tuinstra, Kenneth E.

    The incorporation of mathematical modeling experiences into an undergraduate biology course is described. Detailed expositions of three models used to teach concepts of population ecology are presented, including introductions to major concepts, user instructions, trial data and problem sets. The models described are: 1) an exponential/logistic…

  10. Terminal Dynamics Approach to Discrete Event Systems

    NASA Technical Reports Server (NTRS)

    Zak, Michail; Meyers, Ronald

    1995-01-01

    This paper presents and discusses a mathematical formalism for simulation of discrete event dynamic (DED)-a special type of 'man-made' systems to serve specific purposes of information processing. The main objective of this work is to demonstrate that the mathematical formalism for DED can be based upon a terminal model of Newtonian dynamics which allows one to relax Lipschitz conditions at some discrete points.!.

  11. Modeling Zombie Outbreaks: A Problem-Based Approach to Improving Mathematics One Brain at a Time

    ERIC Educational Resources Information Center

    Lewis, Matthew; Powell, James A.

    2016-01-01

    A great deal of educational literature has focused on problem-based learning (PBL) in mathematics at the primary and secondary level, but arguably there is an even greater need for PBL in college math courses. We present a project centered around the Humans versus Zombies moderated tag game played on the Utah State University campus. We discuss…

  12. The Equation, the Whole Equation, and Nothing but the Equation! One Approach to the Teaching of Linear Equations.

    ERIC Educational Resources Information Center

    Pirie, Susan E. B.; Martin, Lyndon

    1997-01-01

    Presents the results of a case study which looked at the mathematics classroom of one teacher trying to teach mathematics with meaning to pupils or lower ability at the secondary level. Contrasts methods of teaching linear equations to a variety of ability levels and uses the Pirie-Kieren model to account for the successful growth in understanding…

  13. Creativity and Technology in Mathematics: From Story Telling to Algorithmic with Op'Art

    ERIC Educational Resources Information Center

    Mercat, Christian; Filho, Pedro Lealdino; El-Demerdash, Mohamed

    2017-01-01

    This article describes some of the results of the European project mcSquared (http://mc2-project.eu/) regarding the use of Op'Art and optical illusion pieces as a tool to foster modeling and creative mathematical thinking in students. We present briefly the c-book technology and some results we got experimenting it. The Op'Art movement, with…

  14. Extended mathematical model for "in vivo" quantification of the interaction betweeen atazanavir and bilirubin.

    PubMed

    Lozano, Roberto; Domeque, Nieves; Apesteguia, Alberto-Fermín

    2014-02-01

    The objective of the present work was to conduct an "in vivo" analysis of the atazanavir-bilirubin interaction. We developed a new mathematical approach to PK/PDPK models for competitive interaction based on the Michaelis-Menten equation, which was applied to patients with polymorphisms in the gene for UDP-glucuronosyltransferase 1A1 (UGT1A1). Atazanavir is known to induce concentration-dependent increases in bilirubin plasma levels. Thus, we employed our mathematical model to analyse rises in steady state atazanavir and bilirubin concentrations, ultimately plotting a nomogram for detection of suboptimal atazanavir exposure. Application of our model revealed that an absolute value or a steady state increase in bilirubin falling below 3.8Φ µmol/L (where Φ is a correction factor, =1 for UGT1A1 wild type and ≠1 for UGT1A1 variants) could be used to predict suboptimal atazanavir exposure and treatment failure. Thus, we have successfully established a new mathematical approach for pharmacodynamic-pharmacokinetic modelling of the interaction between atazanavir and bilirubin, as it relates to genetic variants of UGT1A1. Taken together, our findings indicate that bilirubin plasma levels represent a valuable marker of atazanavir exposure. © 2013, The American College of Clinical Pharmacology.

  15. Understanding Rasch Measurement: Rasch Models Overview.

    ERIC Educational Resources Information Center

    Wright, Benjamin D.; Mok, Magdalena

    2000-01-01

    Presents an overview of Rasch measurement models that begins with a conceptualization of continuous experiences often captured as discrete observations. Discusses the mathematical properties of the Rasch family of models that allow the transformation of discrete deterministic counts into continuous probabilistic abstractions. Also discusses six of…

  16. Pre-Service Teachers' Modelling Processes through Engagement with Model Eliciting Activities with a Technological Tool

    ERIC Educational Resources Information Center

    Daher, Wajeeh M.; Shahbari, Juhaina Awawdeh

    2015-01-01

    Engaging mathematics students with modelling activities helps them learn mathematics meaningfully. This engagement, in the case of model eliciting activities, helps the students elicit mathematical models by interpreting real-world situation in mathematical ways. This is especially true when the students utilize technology to build the models.…

  17. A mathematical model for calculation of 90Sr absorbed dose in dental tissues: elaboration and comparison to EPR measurements.

    PubMed

    Shishkina, E A; Lyubashevskii, N M; Tolstykh, E I; Ignatiev, E A; Betenekova, T A; Nikiforov, S V

    2001-09-01

    A mathematical model for calculation of the 90Sr absorbed doses in dental tissues is presented. The results of the Monte-Carlo calculations are compared to the data obtained by EPR measurements of dental tissues. Radiometric measurements of the 90Sr concentrations. TLD and EPR dosimetry investigations were performed in animal (dog) study. The importance of the irregular 90Sr distribution in the dentine for absorbed dose formation has been shown. The dominant dose formation factors (main source-tissues) were identified for the crown dentine and enamel. The model has shown agreement with experimental data which allows to determine further directions of the human tooth model development.

  18. A mathematical model of the maximum power density attainable in an alkaline hydrogen/oxygen fuel cell

    NASA Technical Reports Server (NTRS)

    Kimble, Michael C.; White, Ralph E.

    1991-01-01

    A mathematical model of a hydrogen/oxygen alkaline fuel cell is presented that can be used to predict the polarization behavior under various power loads. The major limitations to achieving high power densities are indicated and methods to increase the maximum attainable power density are suggested. The alkaline fuel cell model describes the phenomena occurring in the solid, liquid, and gaseous phases of the anode, separator, and cathode regions based on porous electrode theory applied to three phases. Fundamental equations of chemical engineering that describe conservation of mass and charge, species transport, and kinetic phenomena are used to develop the model by treating all phases as a homogeneous continuum.

  19. Mathematical modeling of PDC bit drilling process based on a single-cutter mechanics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wojtanowicz, A.K.; Kuru, E.

    1993-12-01

    An analytical development of a new mechanistic drilling model for polycrystalline diamond compact (PDC) bits is presented. The derivation accounts for static balance of forces acting on a single PDC cutter and is based on assumed similarity between bit and cutter. The model is fully explicit with physical meanings given to all constants and functions. Three equations constitute the mathematical model: torque, drilling rate, and bit life. The equations comprise cutter`s geometry, rock properties drilling parameters, and four empirical constants. The constants are used to match the model to a PDC drilling process. Also presented are qualitative and predictive verificationsmore » of the model. Qualitative verification shows that the model`s response to drilling process variables is similar to the behavior of full-size PDC bits. However, accuracy of the model`s predictions of PDC bit performance is limited primarily by imprecision of bit-dull evaluation. The verification study is based upon the reported laboratory drilling and field drilling tests as well as field data collected by the authors.« less

  20. Mathematical and Statistical Techniques for Systems Medicine: The Wnt Signaling Pathway as a Case Study.

    PubMed

    MacLean, Adam L; Harrington, Heather A; Stumpf, Michael P H; Byrne, Helen M

    2016-01-01

    The last decade has seen an explosion in models that describe phenomena in systems medicine. Such models are especially useful for studying signaling pathways, such as the Wnt pathway. In this chapter we use the Wnt pathway to showcase current mathematical and statistical techniques that enable modelers to gain insight into (models of) gene regulation and generate testable predictions. We introduce a range of modeling frameworks, but focus on ordinary differential equation (ODE) models since they remain the most widely used approach in systems biology and medicine and continue to offer great potential. We present methods for the analysis of a single model, comprising applications of standard dynamical systems approaches such as nondimensionalization, steady state, asymptotic and sensitivity analysis, and more recent statistical and algebraic approaches to compare models with data. We present parameter estimation and model comparison techniques, focusing on Bayesian analysis and coplanarity via algebraic geometry. Our intention is that this (non-exhaustive) review may serve as a useful starting point for the analysis of models in systems medicine.

  1. A mathematical model for simulating noise suppression of lined ejectors

    NASA Technical Reports Server (NTRS)

    Watson, Willie R.

    1994-01-01

    A mathematical model containing the essential features embodied in the noise suppression of lined ejectors is presented. Although some simplification of the physics is necessary to render the model mathematically tractable, the current model is the most versatile and technologically advanced at the current time. A system of linearized equations and the boundary conditions governing the sound field are derived starting from the equations of fluid dynamics. A nonreflecting boundary condition is developed. In view of the complex nature of the equations, a parametric study requires the use of numerical techniques and modern computers. A finite element algorithm that solves the differential equations coupled with the boundary condition is then introduced. The numerical method results in a matrix equation with several hundred thousand degrees of freedom that is solved efficiently on a supercomputer. The model is validated by comparing results either with exact solutions or with approximate solutions from other works. In each case, excellent correlations are obtained. The usefulness of the model as an optimization tool and the importance of variable impedance liners as a mechanism for achieving broadband suppression within a lined ejector are demonstrated.

  2. Fish biomarkers for environmental monitoring: An integrated model supporting enzyme activity and histopathological lesions

    NASA Astrophysics Data System (ADS)

    Neta, Raimunda Nonata Fortes Carvalho; Torres Junior, Audalio Rebelo

    2014-10-01

    We present a mathematical model describing the association between glutathione-S-transferase activity and brachial lesions in the catfish, Sciades herzbergii (Ariidae) from a polluted port. The catfish were sampled from a port known to be contaminated with heavy metals and organic compounds and from a natural reserve in São Marcos Bay, Brazil. Two biomarkers, hepatic glutathione S-transferase (GST) activity and histopathological lesions, in gills tissue were measured. The values for GST activity were modeled with the occurrence of branchial lesions by fitting a third order polynomial. Results from the mathematical model indicate that GST activity has a strong polynomial relationship with the occurrence of branchial lesions in both the wet and the dry seasons, but only at the polluted port site. The model developed in this study indicates that branchial and hepatic lesions are initiated when GST activity reaches 2.15 μmol min-1 mg protein-1. Beyond this limit, GST activity decreased to very low levels and irreversible histopathological lesions occurred. This mathematical model provides a realistic approach to analyze predictive biomarkers of environmental health status.

  3. Mathematical modeling in realistic mathematics education

    NASA Astrophysics Data System (ADS)

    Riyanto, B.; Zulkardi; Putri, R. I. I.; Darmawijoyo

    2017-12-01

    The purpose of this paper is to produce Mathematical modelling in Realistics Mathematics Education of Junior High School. This study used development research consisting of 3 stages, namely analysis, design and evaluation. The success criteria of this study were obtained in the form of local instruction theory for school mathematical modelling learning which was valid and practical for students. The data were analyzed using descriptive analysis method as follows: (1) walk through, analysis based on the expert comments in the expert review to get Hypothetical Learning Trajectory for valid mathematical modelling learning; (2) analyzing the results of the review in one to one and small group to gain practicality. Based on the expert validation and students’ opinion and answers, the obtained mathematical modeling problem in Realistics Mathematics Education was valid and practical.

  4. Mathematical Problem Solving Ability of Junior High School Students through Ang’s Framework for Mathematical Modelling Instruction

    NASA Astrophysics Data System (ADS)

    Fasni, N.; Turmudi, T.; Kusnandi, K.

    2017-09-01

    This research background of this research is the importance of student problem solving abilities. The purpose of this study is to find out whether there are differences in the ability to solve mathematical problems between students who have learned mathematics using Ang’s Framework for Mathematical Modelling Instruction (AFFMMI) and students who have learned using scientific approach (SA). The method used in this research is a quasi-experimental method with pretest-postest control group design. Data analysis of mathematical problem solving ability using Indepent Sample Test. The results showed that there was a difference in the ability to solve mathematical problems between students who received learning with Ang’s Framework for Mathematical Modelling Instruction and students who received learning with a scientific approach. AFFMMI focuses on mathematical modeling. This modeling allows students to solve problems. The use of AFFMMI is able to improve the solving ability.

  5. Experimental and mathematical model of the interactions in the mixed culture of links in the "producer-consumer" cycle

    NASA Astrophysics Data System (ADS)

    Pisman, T. I.; Galayda, Ya. V.

    The paper presents experimental and mathematical model of interactions between invertebrates the ciliates Paramecium caudatum and the rotifers Brachionus plicatilis and algae Chlorella vulgaris and Scenedesmus quadricauda in the producer -- consumer aquatic biotic cycle with spatially separated components The model describes the dynamics of the mixed culture of ciliates and rotifers in the consumer component feeding on the mixed algal culture of the producer component It has been found that metabolites of the algae Scenedesmus produce an adverse effect on the reproduction of the ciliates P caudatum Taking into account this effect the results of investigation of the mathematical model were in qualitative agreement with the experimental results In the producer -- consumer biotic cycle it was shown that coexistence is impossible in the mixed algal culture of the producer component and in the mixed culture of invertebrates of the consumer component The ciliates P caudatum are driven out by the rotifers Brachionus plicatilis

  6. Mathematical Modeling of Microbial Community Dynamics: A Methodological Review

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Song, Hyun-Seob; Cannon, William R.; Beliaev, Alex S.

    Microorganisms in nature form diverse communities that dynamically change in structure and function in response to environmental variations. As a complex adaptive system, microbial communities show higher-order properties that are not present in individual microbes, but arise from their interactions. Predictive mathematical models not only help to understand the underlying principles of the dynamics and emergent properties of natural and synthetic microbial communities, but also provide key knowledge required for engineering them. In this article, we provide an overview of mathematical tools that include not only current mainstream approaches, but also less traditional approaches that, in our opinion, can bemore » potentially useful. We discuss a broad range of methods ranging from low-resolution supra-organismal to high-resolution individual-based modeling. Particularly, we highlight the integrative approaches that synergistically combine disparate methods. In conclusion, we provide our outlook for the key aspects that should be further developed to move microbial community modeling towards greater predictive power.« less

  7. A logic-based dynamic modeling approach to explicate the evolution of the central dogma of molecular biology.

    PubMed

    Jafari, Mohieddin; Ansari-Pour, Naser; Azimzadeh, Sadegh; Mirzaie, Mehdi

    It is nearly half a century past the age of the introduction of the Central Dogma (CD) of molecular biology. This biological axiom has been developed and currently appears to be all the more complex. In this study, we modified CD by adding further species to the CD information flow and mathematically expressed CD within a dynamic framework by using Boolean network based on its present-day and 1965 editions. We show that the enhancement of the Dogma not only now entails a higher level of complexity, but it also shows a higher level of robustness, thus far more consistent with the nature of biological systems. Using this mathematical modeling approach, we put forward a logic-based expression of our conceptual view of molecular biology. Finally, we show that such biological concepts can be converted into dynamic mathematical models using a logic-based approach and thus may be useful as a framework for improving static conceptual models in biology.

  8. A logic-based dynamic modeling approach to explicate the evolution of the central dogma of molecular biology

    PubMed Central

    Jafari, Mohieddin; Ansari-Pour, Naser; Azimzadeh, Sadegh; Mirzaie, Mehdi

    2017-01-01

    It is nearly half a century past the age of the introduction of the Central Dogma (CD) of molecular biology. This biological axiom has been developed and currently appears to be all the more complex. In this study, we modified CD by adding further species to the CD information flow and mathematically expressed CD within a dynamic framework by using Boolean network based on its present-day and 1965 editions. We show that the enhancement of the Dogma not only now entails a higher level of complexity, but it also shows a higher level of robustness, thus far more consistent with the nature of biological systems. Using this mathematical modeling approach, we put forward a logic-based expression of our conceptual view of molecular biology. Finally, we show that such biological concepts can be converted into dynamic mathematical models using a logic-based approach and thus may be useful as a framework for improving static conceptual models in biology. PMID:29267315

  9. Leaning on Mathematical Habits of Mind

    ERIC Educational Resources Information Center

    Sword, Sarah; Matsuura, Ryota; Cuoco, Al; Kang, Jane; Gates, Miriam

    2018-01-01

    Mathematical modeling has taken on increasing curricular importance in the past decade due in no small measure to the Common Core State Standards in Mathematics (CCSSM) identifying modeling as one of the Standards for Mathematical Practice (SMP 4, CCSSI 2010, p. 7). Although researchers have worked on mathematical modeling (Lesh and Doerr 2003;…

  10. Circular Samples as Objects for Magnetic Resonance Imaging - Mathematical Simulation, Experimental Results

    NASA Astrophysics Data System (ADS)

    Frollo, Ivan; Krafčík, Andrej; Andris, Peter; Přibil, Jiří; Dermek, Tomáš

    2015-12-01

    Circular samples are the frequent objects of "in-vitro" investigation using imaging method based on magnetic resonance principles. The goal of our investigation is imaging of thin planar layers without using the slide selection procedure, thus only 2D imaging or imaging of selected layers of samples in circular vessels, eppendorf tubes,.. compulsorily using procedure "slide selection". In spite of that the standard imaging methods was used, some specificity arise when mathematical modeling of these procedure is introduced. In the paper several mathematical models were presented that were compared with real experimental results. Circular magnetic samples were placed into the homogenous magnetic field of a low field imager based on nuclear magnetic resonance. For experimental verification an MRI 0.178 Tesla ESAOTE Opera imager was used.

  11. Dannie Heineman Prize for Mathematical Physics Prize Lecture: Correlation Functions in Integrable Models II: The Role of Quantum Affine Symmetry

    NASA Astrophysics Data System (ADS)

    Jimbo, Michio

    2013-03-01

    Since the beginning of 1980s, hidden infinite dimensional symmetries have emerged as the origin of integrability: first in soliton theory and then in conformal field theory. Quest for symmetries in quantum integrable models has led to the discovery of quantum groups. On one hand this opened up rapid mathematical developments in representation theory, combinatorics and other fields. On the other hand it has advanced understanding of correlation functions of lattice models, leading to multiple integral formulas in integrable spin chains. We shall review these developments which continue up to the present time.

  12. Physical-mathematical model of optical radiation interaction with biological tissues

    NASA Astrophysics Data System (ADS)

    Kozlovska, Tetyana I.; Kolisnik, Peter F.; Zlepko, Sergey M.; Titova, Natalia V.; Pavlov, Volodymyr S.; Wójcik, Waldemar; Omiotek, Zbigniew; Kozhambardiyeva, Miergul; Zhanpeisova, Aizhan

    2017-08-01

    Remote photoplethysmography (PPG) imaging is an optical technique to remotely assess the local coetaneous microcirculation. In this paper, we present a model and supporting experiments confirming the contribution of skin inhomogeneity to the morphology of PPG waveforms. The physical-mathematical model of distribution of optical radiation in biological tissues was developed. It allows determining the change of intensity of optical radiation depending on such parameters as installation angle of the sensor, biological tissue thickness and the wavelength. We obtained graphics which represent changes of the optical radiation intensity that is registered by photodetector depending on installation angle of the sensor, biological tissue thickness and the extinction coefficient.

  13. A systems analysis of the erythropoietic responses to weightlessness. Volume 1: Mathematical model simulations of the erythropoietic responses to weightlessness

    NASA Technical Reports Server (NTRS)

    Leonard, J. I.

    1985-01-01

    Theoretical responses to weightlessness are summarized. The studies include development and validation of a model of erythropoiesis regulation, analysis of the behavior of erythropoiesis under a variety of conditions, simulations of bed rest and space flight, and an evaluation of ground-based animal studies which were conducted as analogs of zero-g. A review of all relevant space flight findings and a set of testable hypotheses which attempt to explain how red cell mass decreases in space flight are presented. An additional document describes details of the mathematical model used in these studies.

  14. A domain-knowledge-inspired mathematical framework for the description and classification of H&E stained histopathology images.

    PubMed

    Massar, Melody L; Bhagavatula, Ramamurthy; Ozolek, John A; Castro, Carlos A; Fickus, Matthew; Kovačević, Jelena

    2011-10-19

    We present the current state of our work on a mathematical framework for identification and delineation of histopathology images-local histograms and occlusion models. Local histograms are histograms computed over defined spatial neighborhoods whose purpose is to characterize an image locally. This unit of description is augmented by our occlusion models that describe a methodology for image formation. In the context of this image formation model, the power of local histograms with respect to appropriate families of images will be shown through various proved statements about expected performance. We conclude by presenting a preliminary study to demonstrate the power of the framework in the context of histopathology image classification tasks that, while differing greatly in application, both originate from what is considered an appropriate class of images for this framework.

  15. V/STOL tilt rotor study. Volume 5: A mathematical model for real time flight simulation of the Bell model 301 tilt rotor research aircraft

    NASA Technical Reports Server (NTRS)

    Harendra, P. B.; Joglekar, M. J.; Gaffey, T. M.; Marr, R. L.

    1973-01-01

    A mathematical model for real-time flight simulation of a tilt rotor research aircraft was developed. The mathematical model was used to support the aircraft design, pilot training, and proof-of-concept aspects of the development program. The structure of the mathematical model is indicated by a block diagram. The mathematical model differs from that for a conventional fixed wing aircraft principally in the added requirement to represent the dynamics and aerodynamics of the rotors, the interaction of the rotor wake with the airframe, and the rotor control and drive systems. The constraints imposed on the mathematical model are defined.

  16. An implementation framework for wastewater treatment models requiring a minimum programming expertise.

    PubMed

    Rodríguez, J; Premier, G C; Dinsdale, R; Guwy, A J

    2009-01-01

    Mathematical modelling in environmental biotechnology has been a traditionally difficult resource to access for researchers and students without programming expertise. The great degree of flexibility required from model implementation platforms to be suitable for research applications restricts their use to programming expert users. More user friendly software packages however do not normally incorporate the necessary flexibility for most research applications. This work presents a methodology based on Excel and Matlab-Simulink for both flexible and accessible implementation of mathematical models by researchers with and without programming expertise. The models are almost fully defined in an Excel file in which the names and values of the state variables and parameters are easily created. This information is automatically processed in Matlab to create the model structure and almost immediate model simulation, after only a minimum Matlab code definition, is possible. The framework proposed also provides programming expert researchers with a highly flexible and modifiable platform on which to base more complex model implementations. The method takes advantage of structural generalities in most mathematical models of environmental bioprocesses while enabling the integration of advanced elements (e.g. heuristic functions, correlations). The methodology has already been successfully used in a number of research studies.

  17. Mathematization in introductory physics

    NASA Astrophysics Data System (ADS)

    Brahmia, Suzanne M.

    Mathematization is central to STEM disciplines as a cornerstone of the quantitative reasoning that characterizes these fields. Introductory physics is required for most STEM majors in part so that students develop expert-like mathematization. This dissertation describes coordinated research and curriculum development for strengthening mathematization in introductory physics; it blends scholarship in physics and mathematics education in the form of three papers. The first paper explores mathematization in the context of physics, and makes an original contribution to the measurement of physics students' struggle to mathematize. Instructors naturally assume students have a conceptual mastery of algebra before embarking on a college physics course because these students are enrolled in math courses beyond algebra. This paper provides evidence that refutes the validity of this assumption and categorizes some of the barriers students commonly encounter with quantification and representing ideas symbolically. The second paper develops a model of instruction that can help students progress from their starting points to their instructor's desired endpoints. Instructors recognize that the introductory physics course introduces new ideas at an astonishing rate. More than most physicists realize, however, the way that mathematics is used in the course is foreign to a large portion of class. This paper puts forth an instructional model that can move all students toward better quantitative and physical reasoning, despite the substantial variability of those students' initial states. The third paper describes the design and testing of curricular materials that foster mathematical creativity to prepare students to better understand physics reasoning. Few students enter introductory physics with experience generating equations in response to specific challenges involving unfamiliar quantities and units, yet this generative use of mathematics is typical of the thinking involved in doing physics. It contrasts with their more common experience with mathematics as the practice of specified procedures to improve efficiency. This paper describes new curricular materials based on invention instruction provide students with opportunities to generate mathematical relationships in physics, and the paper presents preliminary evidence of the effectiveness of this method with mathematically underprepared engineering students.

  18. Foxes and Rabbits - and a Spreadsheet.

    ERIC Educational Resources Information Center

    Carson, S. R.

    1996-01-01

    Presents a numerical simulation of a simple food chain together with a set of mathematical rules generalizing the model to a food web of any complexity. Discusses some of the model's interesting features and its use by students. (Author/JRH)

  19. Modeling and optimization of Quality of Service routing in Mobile Ad hoc Networks

    NASA Astrophysics Data System (ADS)

    Rafsanjani, Marjan Kuchaki; Fatemidokht, Hamideh; Balas, Valentina Emilia

    2016-01-01

    Mobile ad hoc networks (MANETs) are a group of mobile nodes that are connected without using a fixed infrastructure. In these networks, nodes communicate with each other by forming a single-hop or multi-hop network. To design effective mobile ad hoc networks, it is important to evaluate the performance of multi-hop paths. In this paper, we present a mathematical model for a routing protocol under energy consumption and packet delivery ratio of multi-hop paths. In this model, we use geometric random graphs rather than random graphs. Our proposed model finds effective paths that minimize the energy consumption and maximizes the packet delivery ratio of the network. Validation of the mathematical model is performed through simulation.

  20. Wind shear modeling for aircraft hazard definition

    NASA Technical Reports Server (NTRS)

    Frost, W.; Camp, D. W.; Wang, S. T.

    1978-01-01

    Mathematical models of wind profiles were developed for use in fast time and manned flight simulation studies aimed at defining and eliminating these wind shear hazards. A set of wind profiles and associated wind shear characteristics for stable and neutral boundary layers, thunderstorms, and frontal winds potentially encounterable by aircraft in the terminal area are given. Engineering models of wind shear for direct hazard analysis are presented in mathematical formulae, graphs, tables, and computer lookup routines. The wind profile data utilized to establish the models are described as to location, how obtained, time of observation and number of data points up to 500 m. Recommendations, engineering interpretations and guidelines for use of the data are given and the range of applicability of the wind shear models is described.

  1. Dimensionless Analysis and Numerical Modeling of Rebalancing Phenomena During Levitation

    NASA Astrophysics Data System (ADS)

    Gao, Lei; Shi, Zhe; Li, Donghui; McLean, Alexander; Chattopadhyay, Kinnor

    2016-06-01

    Electromagnetic levitation (EML) has proved to be a powerful tool for research activities in areas pertaining to materials physics and engineering. The customized EML setups in various fields, ranging from solidification to nanomaterial manufacturing, require the designing of stable levitation systems. Since the elevated droplet is opaque, the most effective way to research on EML is mathematical modeling. In the present study, a 3D model was built to investigate the rebalancing phenomenon causing instabilities during droplet melting. A mathematical model modified based on Hooke's law (spring) was proposed to describe the levitation system. This was combined with dimensionless analysis to investigate the generation of levitation forces as it will significantly affect the behavior of the spring model.

  2. Developing Students' Reflections on the Function and Status of Mathematical Modeling in Different Scientific Practices: History as a Provider of Cases

    ERIC Educational Resources Information Center

    Kjeldsen, Tinne Hoff; Blomhøj, Morten

    2013-01-01

    Mathematical models and mathematical modeling play different roles in the different areas and problems in which they are used. The function and status of mathematical modeling and models in the different areas depend on the scientific practice as well as the underlying philosophical and theoretical position held by the modeler(s) and the…

  3. Strong Inference in Mathematical Modeling: A Method for Robust Science in the Twenty-First Century.

    PubMed

    Ganusov, Vitaly V

    2016-01-01

    While there are many opinions on what mathematical modeling in biology is, in essence, modeling is a mathematical tool, like a microscope, which allows consequences to logically follow from a set of assumptions. Only when this tool is applied appropriately, as microscope is used to look at small items, it may allow to understand importance of specific mechanisms/assumptions in biological processes. Mathematical modeling can be less useful or even misleading if used inappropriately, for example, when a microscope is used to study stars. According to some philosophers (Oreskes et al., 1994), the best use of mathematical models is not when a model is used to confirm a hypothesis but rather when a model shows inconsistency of the model (defined by a specific set of assumptions) and data. Following the principle of strong inference for experimental sciences proposed by Platt (1964), I suggest "strong inference in mathematical modeling" as an effective and robust way of using mathematical modeling to understand mechanisms driving dynamics of biological systems. The major steps of strong inference in mathematical modeling are (1) to develop multiple alternative models for the phenomenon in question; (2) to compare the models with available experimental data and to determine which of the models are not consistent with the data; (3) to determine reasons why rejected models failed to explain the data, and (4) to suggest experiments which would allow to discriminate between remaining alternative models. The use of strong inference is likely to provide better robustness of predictions of mathematical models and it should be strongly encouraged in mathematical modeling-based publications in the Twenty-First century.

  4. Aids to determining fuel models for estimating fire behavior

    Treesearch

    Hal E. Anderson

    1982-01-01

    Presents photographs of wildland vegetation appropriate for the 13 fuel models used in mathematical models of fire behavior. Fuel model descriptions include fire behavior associated with each fuel and its physical characteristics. A similarity chart cross-references the 13 fire behavior fuel models to the 20 fuel models used in the National Fire Danger Rating System....

  5. METHODS FOR MODELING PARTICLE DEPOSITION AS A FUNCTION OF AGE. (R827352C004)

    EPA Science Inventory

    The purpose of this paper is to review the application of mathematical models of inhaled particle deposition to people of various ages. The basic considerations of aerosol physics, biological characteristics and model structure are presented along with limitations inherent in ...

  6. Stochastic Robust Mathematical Programming Model for Power System Optimization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Cong; Changhyeok, Lee; Haoyong, Chen

    2016-01-01

    This paper presents a stochastic robust framework for two-stage power system optimization problems with uncertainty. The model optimizes the probabilistic expectation of different worst-case scenarios with ifferent uncertainty sets. A case study of unit commitment shows the effectiveness of the proposed model and algorithms.

  7. Estimating wildfire behavior and effects

    Treesearch

    Frank A. Albini

    1976-01-01

    This paper presents a brief survey of the research literature on wildfire behavior and effects and assembles formulae and graphical computation aids based on selected theoretical and empirical models. The uses of mathematical fire behavior models are discussed, and the general capabilities and limitations of currently available models are outlined.

  8. A MATHEMATICAL MODEL FOR THE KINETICS OF THE MALE REPRODUCTIVE ENDOCRINE SYSTEM

    EPA Science Inventory

    In this presentation a model for the hormonal regulation of the reproductive endocrine system in the adult male rat will be discussed. The model includes a description of the kinetics of the androgenic hormones testosterone and dihydrotestosterone, as well as the receptor-mediate...

  9. Does perceived teacher affective support matter for middle school students in mathematics classrooms?

    PubMed

    Sakiz, Gonul; Pape, Stephen J; Hoy, Anita Woolfolk

    2012-04-01

    The purpose of the present study was to explore the importance of perceived teacher affective support in relation to sense of belonging, academic enjoyment, academic hopelessness, academic self-efficacy, and academic effort in middle school mathematics classrooms. A self-report survey was administered to 317 seventh- and eighth-grade students in 5 public middle schools. Structural equation modeling indicated significant associations between perceived teacher affective support and middle school students' motivational, emotional, and behavioral outcomes. The structural model explained a significant proportion of variance in students' sense of belonging (42%), academic enjoyment (43%), self-efficacy beliefs (43%), academic hopelessness (18%), and academic effort (32%) in mathematics classrooms. In addition to providing the basis for a concise new measure of perceived teacher affective support, these findings point to the importance of students' perceptions of the affective climate within learning environments for promoting academic enjoyment, academic self-efficacy, and academic effort in mathematics. Copyright © 2011 Society for the Study of School Psychology. Published by Elsevier Ltd. All rights reserved.

  10. Summer Camp of Mathematical Modeling in China

    ERIC Educational Resources Information Center

    Tian, Xiaoxi; Xie, Jinxing

    2013-01-01

    The Summer Camp of Mathematical Modeling in China is a recently created experience designed to further Chinese students' academic pursuits in mathematical modeling. Students are given more than three months to research on a mathematical modeling project. Researchers and teams with outstanding projects are invited to the Summer Camp to present…

  11. Equations to assess the impact resistance of fiber composites

    NASA Technical Reports Server (NTRS)

    Chamis, C. C.; Hanson, M. P.; Serafini, T. T.

    1972-01-01

    Numerical analysis of impact resistance of composite materials containing fibers is discussed. Mathematical model of longitudinal impact resistance is presented. Potential impact resistance of various fiber composites as obtained by numerical analysis is presented as plotted curve.

  12. Mathematical Modeling of Protein Misfolding Mechanisms in Neurological Diseases: A Historical Overview.

    PubMed

    Carbonell, Felix; Iturria-Medina, Yasser; Evans, Alan C

    2018-01-01

    Protein misfolding refers to a process where proteins become structurally abnormal and lose their specific 3-dimensional spatial configuration. The histopathological presence of misfolded protein (MP) aggregates has been associated as the primary evidence of multiple neurological diseases, including Prion diseases, Alzheimer's disease, Parkinson's disease, and Creutzfeldt-Jacob disease. However, the exact mechanisms of MP aggregation and propagation, as well as their impact in the long-term patient's clinical condition are still not well understood. With this aim, a variety of mathematical models has been proposed for a better insight into the kinetic rate laws that govern the microscopic processes of protein aggregation. Complementary, another class of large-scale models rely on modern molecular imaging techniques for describing the phenomenological effects of MP propagation over the whole brain. Unfortunately, those neuroimaging-based studies do not take full advantage of the tremendous capabilities offered by the chemical kinetics modeling approach. Actually, it has been barely acknowledged that the vast majority of large-scale models have foundations on previous mathematical approaches that describe the chemical kinetics of protein replication and propagation. The purpose of the current manuscript is to present a historical review about the development of mathematical models for describing both microscopic processes that occur during the MP aggregation and large-scale events that characterize the progression of neurodegenerative MP-mediated diseases.

  13. A new mathematical model of bacterial interactions in two-species oral biofilms

    PubMed Central

    Martin, Bénédicte; Tamanai-Shacoori, Zohreh; Bronsard, Julie; Ginguené, Franck; Meuric, Vincent

    2017-01-01

    Periodontitis are bacterial inflammatory diseases, where the bacterial biofilms present on the tooth-supporting tissues switch from a healthy state towards a pathogenic state. Among bacterial species involved in the disease, Porphyromonas gingivalis has been shown to induce dysbiosis, and to induce virulence of otherwise healthy bacteria like Streptococcus gordonii. During biofilm development, primary colonizers such as S. gordonii first attach to the surface and allow the subsequent adhesion of periodontal pathogens such as P. gingivalis. Interactions between those two bacteria have been extensively studied during the adhesion step of the biofilm. The aim of the study was to understand interactions of both species during the growing phase of the biofilm, for which little knowledge is available, using a mathematical model. This two-species biofilm model was based on a substrate-dependent growth, implemented with damage parameters, and validated thanks to data obtained on experimental biofilms. Three different hypothesis of interactions were proposed and assayed using this model: independence, competition between both bacteria species, or induction of toxicity by one species for the other species. Adequacy between experimental and simulated biofilms were found with the last hypothetic mathematical model. This new mathematical model of two species bacteria biofilms, dependent on different substrates for growing, can be applied to any bacteria species, environmental conditions, or steps of biofilm development. It will be of great interest for exploring bacterial interactions in biofilm conditions. PMID:28253369

  14. Sensitivity of the Arctic Ocean gas hydrate to climate changes in the period of 1948-2015

    NASA Astrophysics Data System (ADS)

    Malakhova, Valentina V.; Golubeva, Elena N.; Iakshina, Dina F.

    2017-11-01

    The objective of the present study is to analyze the interactions between a methane hydrates stability zone and the ocean temperature variations and to define the hydrate sensitivity to the contemporary warming in the Arctic Ocean. To obtain the spatial-temporary variability of the ocean bottom temperature we employ the ICMMG regional Arctic-North Atlantic ocean model that has been developed in the Institute of Computational Mathematics and Mathematical Geophysics. With the ice-ocean model the Arctic bottom water temperatures were analyzed. The resulting warming ocean bottom water is spatially inhomogeneous, with a strong impact by the Atlantic inflow on shallow regions of 200-500 m depth. Results of the mathematical modeling of the dynamics of methane hydrate stability zone in the Arctic Ocean sediment are reported. We find that the reduction of the methane hydrate stability zone occurs in the Arctic Ocean between 250 and 400 m water depths within the upper 100 m of sediment in the area influenced by the Atlantic inflow. We have identified the areas of the Arctic Ocean where an increase in methane release is probable to occur at the present time.

  15. Strong Inference in Mathematical Modeling: A Method for Robust Science in the Twenty-First Century

    PubMed Central

    Ganusov, Vitaly V.

    2016-01-01

    While there are many opinions on what mathematical modeling in biology is, in essence, modeling is a mathematical tool, like a microscope, which allows consequences to logically follow from a set of assumptions. Only when this tool is applied appropriately, as microscope is used to look at small items, it may allow to understand importance of specific mechanisms/assumptions in biological processes. Mathematical modeling can be less useful or even misleading if used inappropriately, for example, when a microscope is used to study stars. According to some philosophers (Oreskes et al., 1994), the best use of mathematical models is not when a model is used to confirm a hypothesis but rather when a model shows inconsistency of the model (defined by a specific set of assumptions) and data. Following the principle of strong inference for experimental sciences proposed by Platt (1964), I suggest “strong inference in mathematical modeling” as an effective and robust way of using mathematical modeling to understand mechanisms driving dynamics of biological systems. The major steps of strong inference in mathematical modeling are (1) to develop multiple alternative models for the phenomenon in question; (2) to compare the models with available experimental data and to determine which of the models are not consistent with the data; (3) to determine reasons why rejected models failed to explain the data, and (4) to suggest experiments which would allow to discriminate between remaining alternative models. The use of strong inference is likely to provide better robustness of predictions of mathematical models and it should be strongly encouraged in mathematical modeling-based publications in the Twenty-First century. PMID:27499750

  16. Numerical simulation of dynamics of brushless dc motors for aerospace and other applications. Volume 1: Model development and applications, part B

    NASA Technical Reports Server (NTRS)

    Demerdash, N. A. O.; Nehl, T. W.

    1979-01-01

    A mathematical model was developed and computerized simulations were obtained for a brushless dc motor. Experimentally obtained oscillograms of the machine phase currents are presented and the corresponding current and voltage waveforms for various modes of operation of the motor are presented and discussed.

  17. A multi-objective programming model for assessment the GHG emissions in MSW management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mavrotas, George, E-mail: mavrotas@chemeng.ntua.gr; Skoulaxinou, Sotiria; Gakis, Nikos

    2013-09-15

    Highlights: • The multi-objective multi-period optimization model. • The solution approach for the generation of the Pareto front with mathematical programming. • The very detailed description of the model (decision variables, parameters, equations). • The use of IPCC 2006 guidelines for landfill emissions (first order decay model) in the mathematical programming formulation. - Abstract: In this study a multi-objective mathematical programming model is developed for taking into account GHG emissions for Municipal Solid Waste (MSW) management. Mathematical programming models are often used for structure, design and operational optimization of various systems (energy, supply chain, processes, etc.). The last twenty yearsmore » they are used all the more often in Municipal Solid Waste (MSW) management in order to provide optimal solutions with the cost objective being the usual driver of the optimization. In our work we consider the GHG emissions as an additional criterion, aiming at a multi-objective approach. The Pareto front (Cost vs. GHG emissions) of the system is generated using an appropriate multi-objective method. This information is essential to the decision maker because he can explore the trade-offs in the Pareto curve and select his most preferred among the Pareto optimal solutions. In the present work a detailed multi-objective, multi-period mathematical programming model is developed in order to describe the waste management problem. Apart from the bi-objective approach, the major innovations of the model are (1) the detailed modeling considering 34 materials and 42 technologies, (2) the detailed calculation of the energy content of the various streams based on the detailed material balances, and (3) the incorporation of the IPCC guidelines for the CH{sub 4} generated in the landfills (first order decay model). The equations of the model are described in full detail. Finally, the whole approach is illustrated with a case study referring to the application of the model in a Greek region.« less

  18. Using Covariation Reasoning to Support Mathematical Modeling

    ERIC Educational Resources Information Center

    Jacobson, Erik

    2014-01-01

    For many students, making connections between mathematical ideas and the real world is one of the most intriguing and rewarding aspects of the study of mathematics. In the Common Core State Standards for Mathematics (CCSSI 2010), mathematical modeling is highlighted as a mathematical practice standard for all grades. To engage in mathematical…

  19. An Examination of Pre-Service Mathematics Teachers' Approaches to Construct and Solve Mathematical Modelling Problems

    ERIC Educational Resources Information Center

    Bukova-Guzel, Esra

    2011-01-01

    This study examines the approaches displayed by pre-service mathematics teachers in their experiences of constructing mathematical modelling problems and the extent to which they perform the modelling process when solving the problems they construct. This case study was carried out with 35 pre-service teachers taking the Mathematical Modelling…

  20. Mathematical modeling of damage in unidirectional composites

    NASA Technical Reports Server (NTRS)

    Goree, J. G.; Dharani, L. R.; Jones, W. F.

    1981-01-01

    A review of some approximate analytical models for damaged, fiber reinforced composite materials is presented. Using the classical shear lag stress displacement assumption, solutions are presented for a unidirectional laminate containing a notch, a rectangular cut-out, and a circular hole. The models account for longitudinal matrix yielding and splitting as well as transverse matrix yielding and fiber breakage. The constraining influence of a cover sheet on the unidirectional laminate is also modeled.

  1. Modelling water hammer in viscoelastic pipelines: short brief

    NASA Astrophysics Data System (ADS)

    Urbanowicz, K.; Firkowski, M.; Zarzycki, Z.

    2016-10-01

    The model of water hammer in viscoelastic pipelines is analyzed. An appropriate mathematical model of water hammer in polymer pipelines is presented. An additional term has been added to continuity equation to describe the retarded deformation of the pipe wall. The mechanical behavior of viscoelastic material is described by generalized Kelvin-Voigt model. The comparison of numerical simulation and experimental data from well known papers is presented. Short discussion about obtained results are given.

  2. The knowledge instinct, cognitive algorithms, modeling of language and cultural evolution

    NASA Astrophysics Data System (ADS)

    Perlovsky, Leonid I.

    2008-04-01

    The talk discusses mechanisms of the mind and their engineering applications. The past attempts at designing "intelligent systems" encountered mathematical difficulties related to algorithmic complexity. The culprit turned out to be logic, which in one way or another was used not only in logic rule systems, but also in statistical, neural, and fuzzy systems. Algorithmic complexity is related to Godel's theory, a most fundamental mathematical result. These difficulties were overcome by replacing logic with a dynamic process "from vague to crisp," dynamic logic. It leads to algorithms overcoming combinatorial complexity, and resulting in orders of magnitude improvement in classical problems of detection, tracking, fusion, and prediction in noise. I present engineering applications to pattern recognition, detection, tracking, fusion, financial predictions, and Internet search engines. Mathematical and engineering efficiency of dynamic logic can also be understood as cognitive algorithm, which describes fundamental property of the mind, the knowledge instinct responsible for all our higher cognitive functions: concepts, perception, cognition, instincts, imaginations, intuitions, emotions, including emotions of the beautiful. I present our latest results in modeling evolution of languages and cultures, their interactions in these processes, and role of music in cultural evolution. Experimental data is presented that support the theory. Future directions are outlined.

  3. Spatial-Operator Algebra For Robotic Manipulators

    NASA Technical Reports Server (NTRS)

    Rodriguez, Guillermo; Kreutz, Kenneth K.; Milman, Mark H.

    1991-01-01

    Report discusses spatial-operator algebra developed in recent studies of mathematical modeling, control, and design of trajectories of robotic manipulators. Provides succinct representation of mathematically complicated interactions among multiple joints and links of manipulator, thereby relieving analyst of most of tedium of detailed algebraic manipulations. Presents analytical formulation of spatial-operator algebra, describes some specific applications, summarizes current research, and discusses implementation of spatial-operator algebra in the Ada programming language.

  4. DaMoScope and its internet graphics for the visual control of adjusting mathematical models describing experimental data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Belousov, V. I.; Ezhela, V. V.; Kuyanov, Yu. V., E-mail: Yu.Kuyanov@gmail.com

    The experience of using the dynamic atlas of the experimental data and mathematical models of their description in the problems of adjusting parametric models of observable values depending on kinematic variables is presented. The functional possibilities of an image of a large number of experimental data and the models describing them are shown by examples of data and models of observable values determined by the amplitudes of elastic scattering of hadrons. The Internet implementation of an interactive tool DaMoScope and its interface with the experimental data and codes of adjusted parametric models with the parameters of the best description ofmore » data are schematically shown. The DaMoScope codes are freely available.« less

  5. Predicting introductory programming performance: A multi-institutional multivariate study

    NASA Astrophysics Data System (ADS)

    Bergin, Susan; Reilly, Ronan

    2006-12-01

    A model for predicting student performance on introductory programming modules is presented. The model uses attributes identified in a study carried out at four third-level institutions in the Republic of Ireland. Four instruments were used to collect the data and over 25 attributes were examined. A data reduction technique was applied and a logistic regression model using 10-fold stratified cross validation was developed. The model used three attributes: Leaving Certificate Mathematics result (final mathematics examination at second level), number of hours playing computer games while taking the module and programming self-esteem. Prediction success was significant with 80% of students correctly classified. The model also works well on a per-institution level. A discussion on the implications of the model is provided and future work is outlined.

  6. Application of a Model for Simulating the Vacuum Arc Remelting Process in Titanium Alloys

    NASA Astrophysics Data System (ADS)

    Patel, Ashish; Tripp, David W.; Fiore, Daniel

    Mathematical modeling is routinely used in the process development and production of advanced aerospace alloys to gain greater insight into system dynamics and to predict the effect of process modifications or upsets on final properties. This article describes the application of a 2-D mathematical VAR model presented in previous LMPC meetings. The impact of process parameters on melt pool geometry, solidification behavior, fluid-flow and chemistry in Ti-6Al-4V ingots will be discussed. Model predictions were first validated against the measured characteristics of industrially produced ingots, and process inputs and model formulation were adjusted to match macro-etched pool shapes. The results are compared to published data in the literature. Finally, the model is used to examine ingot chemistry during successive VAR melts.

  7. Mathematical Modeling of Rotary Blood Pumps in a Pulsatile In Vitro Flow Environment.

    PubMed

    Pirbodaghi, Tohid

    2017-08-01

    Nowadays, sacrificing animals to develop medical devices and receive regulatory approval has become more common, which increases ethical concerns. Although in vivo tests are necessary for development and evaluation of new devices, nonetheless, with appropriate in vitro setups and mathematical models, a part of the validation process can be performed using these models to reduce the number of sacrificed animals. The main aim of this study is to present a mathematical model simulating the hydrodynamic function of a rotary blood pump (RBP) in a pulsatile in vitro flow environment. This model relates the pressure head of the RBP to the flow rate, rotational speed, and time derivatives of flow rate and rotational speed. To identify the model parameters, an in vitro setup was constructed consisting of a piston pump, a compliance chamber, a throttle, a buffer reservoir, and the CentriMag RBP. A 40% glycerin-water mixture as a blood analog fluid and deionized water were used in the hydraulic circuit to investigate the effect of viscosity and density of the working fluid on the model parameters. First, model variables were physically measured and digitally acquired. Second, an identification algorithm based on regression analysis was used to derive the model parameters. Third, the completed model was validated with a totally different set of in vitro data. The model is usable for both mathematical simulations of the interaction between the pump and heart and indirect pressure measurement in a clinical context. © 2017 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  8. Mathematical programming formulations for satellite synthesis

    NASA Technical Reports Server (NTRS)

    Bhasin, Puneet; Reilly, Charles H.

    1987-01-01

    The problem of satellite synthesis can be described as optimally allotting locations and sometimes frequencies and polarizations, to communication satellites so that interference from unwanted satellite signals does not exceed a specified threshold. In this report, mathematical programming models and optimization methods are used to solve satellite synthesis problems. A nonlinear programming formulation which is solved using Zoutendijk's method and a gradient search method is described. Nine mixed integer programming models are considered. Results of computer runs with these nine models and five geographically compatible scenarios are presented and evaluated. A heuristic solution procedure is also used to solve two of the models studied. Heuristic solutions to three large synthesis problems are presented. The results of our analysis show that the heuristic performs very well, both in terms of solution quality and solution time, on the two models to which it was applied. It is concluded that the heuristic procedure is the best of the methods considered for solving satellite synthesis problems.

  9. A Toy Model of Electrodynamics in (1 + 1) Dimensions

    ERIC Educational Resources Information Center

    Boozer, A. D.

    2007-01-01

    A model is presented that describes a scalar field interacting with a point particle in (1+1) dimensions. The model exhibits many of the same phenomena that appear in classical electrodynamics, such as radiation and radiation damping, yet has a much simpler mathematical structure. By studying these phenomena in a highly simplified model, the…

  10. Performance modeling of automated manufacturing systems

    NASA Astrophysics Data System (ADS)

    Viswanadham, N.; Narahari, Y.

    A unified and systematic treatment is presented of modeling methodologies and analysis techniques for performance evaluation of automated manufacturing systems. The book is the first treatment of the mathematical modeling of manufacturing systems. Automated manufacturing systems are surveyed and three principal analytical modeling paradigms are discussed: Markov chains, queues and queueing networks, and Petri nets.

  11. Learning to teach mathematical modelling in secondary and tertiary education

    NASA Astrophysics Data System (ADS)

    Ferri, Rita Borromeo

    2017-07-01

    Since 2003 mathematical modelling in Germany is not only a topic for scientific disciplines in university mathematics courses, but also in school starting with primary school. This paper shows what mathematical modelling means in school and how it can be taught as a basis for complex modeling problems in tertiary education.

  12. The Routine Fitting of Kinetic Data to Models

    PubMed Central

    Berman, Mones; Shahn, Ezra; Weiss, Marjory F.

    1962-01-01

    A mathematical formalism is presented for use with digital computers to permit the routine fitting of data to physical and mathematical models. Given a set of data, the mathematical equations describing a model, initial conditions for an experiment, and initial estimates for the values of model parameters, the computer program automatically proceeds to obtain a least squares fit of the data by an iterative adjustment of the values of the parameters. When the experimental measures are linear combinations of functions, the linear coefficients for a least squares fit may also be calculated. The values of both the parameters of the model and the coefficients for the sum of functions may be unknown independent variables, unknown dependent variables, or known constants. In the case of dependence, only linear dependencies are provided for in routine use. The computer program includes a number of subroutines, each one of which performs a special task. This permits flexibility in choosing various types of solutions and procedures. One subroutine, for example, handles linear differential equations, another, special non-linear functions, etc. The use of analytic or numerical solutions of equations is possible. PMID:13867975

  13. Stabilized FE simulation of prototype thermal-hydraulics problems with integrated adjoint-based capabilities

    NASA Astrophysics Data System (ADS)

    Shadid, J. N.; Smith, T. M.; Cyr, E. C.; Wildey, T. M.; Pawlowski, R. P.

    2016-09-01

    A critical aspect of applying modern computational solution methods to complex multiphysics systems of relevance to nuclear reactor modeling, is the assessment of the predictive capability of specific proposed mathematical models. In this respect the understanding of numerical error, the sensitivity of the solution to parameters associated with input data, boundary condition uncertainty, and mathematical models is critical. Additionally, the ability to evaluate and or approximate the model efficiently, to allow development of a reasonable level of statistical diagnostics of the mathematical model and the physical system, is of central importance. In this study we report on initial efforts to apply integrated adjoint-based computational analysis and automatic differentiation tools to begin to address these issues. The study is carried out in the context of a Reynolds averaged Navier-Stokes approximation to turbulent fluid flow and heat transfer using a particular spatial discretization based on implicit fully-coupled stabilized FE methods. Initial results are presented that show the promise of these computational techniques in the context of nuclear reactor relevant prototype thermal-hydraulics problems.

  14. Stabilized FE simulation of prototype thermal-hydraulics problems with integrated adjoint-based capabilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shadid, J.N., E-mail: jnshadi@sandia.gov; Department of Mathematics and Statistics, University of New Mexico; Smith, T.M.

    A critical aspect of applying modern computational solution methods to complex multiphysics systems of relevance to nuclear reactor modeling, is the assessment of the predictive capability of specific proposed mathematical models. In this respect the understanding of numerical error, the sensitivity of the solution to parameters associated with input data, boundary condition uncertainty, and mathematical models is critical. Additionally, the ability to evaluate and or approximate the model efficiently, to allow development of a reasonable level of statistical diagnostics of the mathematical model and the physical system, is of central importance. In this study we report on initial efforts tomore » apply integrated adjoint-based computational analysis and automatic differentiation tools to begin to address these issues. The study is carried out in the context of a Reynolds averaged Navier–Stokes approximation to turbulent fluid flow and heat transfer using a particular spatial discretization based on implicit fully-coupled stabilized FE methods. Initial results are presented that show the promise of these computational techniques in the context of nuclear reactor relevant prototype thermal-hydraulics problems.« less

  15. Stabilized FE simulation of prototype thermal-hydraulics problems with integrated adjoint-based capabilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shadid, J. N.; Smith, T. M.; Cyr, E. C.

    A critical aspect of applying modern computational solution methods to complex multiphysics systems of relevance to nuclear reactor modeling, is the assessment of the predictive capability of specific proposed mathematical models. The understanding of numerical error, the sensitivity of the solution to parameters associated with input data, boundary condition uncertainty, and mathematical models is critical. Additionally, the ability to evaluate and or approximate the model efficiently, to allow development of a reasonable level of statistical diagnostics of the mathematical model and the physical system, is of central importance. In our study we report on initial efforts to apply integrated adjoint-basedmore » computational analysis and automatic differentiation tools to begin to address these issues. The study is carried out in the context of a Reynolds averaged Navier–Stokes approximation to turbulent fluid flow and heat transfer using a particular spatial discretization based on implicit fully-coupled stabilized FE methods. We present the initial results that show the promise of these computational techniques in the context of nuclear reactor relevant prototype thermal-hydraulics problems.« less

  16. Stabilized FE simulation of prototype thermal-hydraulics problems with integrated adjoint-based capabilities

    DOE PAGES

    Shadid, J. N.; Smith, T. M.; Cyr, E. C.; ...

    2016-05-20

    A critical aspect of applying modern computational solution methods to complex multiphysics systems of relevance to nuclear reactor modeling, is the assessment of the predictive capability of specific proposed mathematical models. The understanding of numerical error, the sensitivity of the solution to parameters associated with input data, boundary condition uncertainty, and mathematical models is critical. Additionally, the ability to evaluate and or approximate the model efficiently, to allow development of a reasonable level of statistical diagnostics of the mathematical model and the physical system, is of central importance. In our study we report on initial efforts to apply integrated adjoint-basedmore » computational analysis and automatic differentiation tools to begin to address these issues. The study is carried out in the context of a Reynolds averaged Navier–Stokes approximation to turbulent fluid flow and heat transfer using a particular spatial discretization based on implicit fully-coupled stabilized FE methods. We present the initial results that show the promise of these computational techniques in the context of nuclear reactor relevant prototype thermal-hydraulics problems.« less

  17. Orbital Debris Modeling

    NASA Technical Reports Server (NTRS)

    Liou, J. C.

    2012-01-01

    Presentation outlne: (1) The NASA Orbital Debris (OD) Engineering Model -- A mathematical model capable of predicting OD impact risks for the ISS and other critical space assets (2) The NASA OD Evolutionary Model -- A physical model capable of predicting future debris environment based on user-specified scenarios (3) The NASA Standard Satellite Breakup Model -- A model describing the outcome of a satellite breakup (explosion or collision)

  18. Development of a Multidisciplinary Middle School Mathematics Infusion Model

    ERIC Educational Resources Information Center

    Russo, Maria; Hecht, Deborah; Burghardt, M. David; Hacker, Michael; Saxman, Laura

    2011-01-01

    The National Science Foundation (NSF) funded project "Mathematics, Science, and Technology Partnership" (MSTP) developed a multidisciplinary instructional model for connecting mathematics to science, technology and engineering content areas at the middle school level. Specifically, the model infused mathematics into middle school curriculum…

  19. Mathematical model for thermal solar collectors by using magnetohydrodynamic Maxwell nanofluid with slip conditions, thermal radiation and variable thermal conductivity

    NASA Astrophysics Data System (ADS)

    Mahmood, Asif; Aziz, Asim; Jamshed, Wasim; Hussain, Sajid

    Solar energy is the cleanest, renewable and most abundant source of energy available on earth. The main use of solar energy is to heat and cool buildings, heat water and to generate electricity. There are two types of solar energy collection system, the photovoltaic systems and the solar thermal collectors. The efficiency of any solar thermal system depend on the thermophysical properties of the operating fluids and the geometry/length of the system in which fluid is flowing. In the present research a simplified mathematical model for the solar thermal collectors is considered in the form of non-uniform unsteady stretching surface. The flow is induced by a non-uniform stretching of the porous sheet and the uniform magnetic field is applied in the transverse direction to the flow. The non-Newtonian Maxwell fluid model is utilized for the working fluid along with slip boundary conditions. Moreover the high temperature effect of thermal radiation and temperature dependent thermal conductivity are also included in the present model. The mathematical formulation is carried out through a boundary layer approach and the numerical computations are carried out for cu-water and TiO2 -water nanofluids. Results are presented for the velocity and temperature profiles as well as the skin friction coefficient and Nusselt number and the discussion is concluded on the effect of various governing parameters on the motion, temperature variation, velocity gradient and the rate of heat transfer at the boundary.

  20. A model for calculating expected performance of the Apollo unified S-band (USB) communication system

    NASA Technical Reports Server (NTRS)

    Schroeder, N. W.

    1971-01-01

    A model for calculating the expected performance of the Apollo unified S-band (USB) communication system is presented. The general organization of the Apollo USB is described. The mathematical model is reviewed and the computer program for implementation of the calculations is included.

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