Potential Information and Decision Support System Applications for a Civil Engineering RED HORSE Squadron.

DTIC Science & Technology

1987-09-01

APPLICATIONS FOR A CIVIL ENGINEERILaG RED HORSE SQUADRON THESIS Arvil E. White III Captain, USAF AFIT/GE:4/LSM/87S-27 .... DEPARTMENT OF THE AIR FORCE...DT1TO-SJAN 0 419880 POTENTIAL INFORMATION AND DECISION SUPPORT SYSTEM APPLICATIONS FOR A CIVIL ENGINEERILiG RED HORSE SQUADRON IAooession For THESIS NI R...INFORMATION AND DECISION SUPPORT SYSTrEM APPLICATIONS FOR A CIVIL ENGINEERINGX :.. 4. RED HORSE SQUADRON - THESIS -4 Presented to the Faculty of the

Present-day potentialities of endoscopic diagnostics and treatment of early cancer in respiratory and digestive tracts

NASA Astrophysics Data System (ADS)

Sokolov, Victor V.; Zharkova, Natalia N.; Filonenko, E. V.; Telegina, L. V.; Karpova, E. S.

1999-12-01

The paper presents the latest potentialities of the endoscopic fluorescent diagnostics as well as endoscopic electric-, laser surgery and photodynamic therapy (PDT) of the early cancer in the respiratory and digestive tracts. We present in detail indication and factors determining the application of the endoscopic resection of the tumor. The advantages of the combination application of PDT, electro-, Nd:YAG laser surgery and brachitherapy are stressed. The near and remote results of endoscopic treatment of the early cancer in larynx (37), lung (109), esophagus (39) and stomach (58) are shown.

Ecological Land Classification: Applications to Identify the Productive Potential of Southern Forests

Treesearch

Dennis L. Mengel; D. Thompson Tew; [Editors

1991-01-01

Eighteen papers representing four categories-Regional Overviews; Classification System Development; Classification System Interpretation; Mapping/GIS Applications in Classification Systems-present the state of the art in forest-land classification and evaluation in the South. In addition, nine poster papers are presented.

UNCERTAINTY IN LEACHING POTENTIAL OF NONPOINT SOURCE POLLUTANTS WITH APPLICATION TO GIS

EPA Science Inventory

This paper presents a stochastic framework for the assessment of groundwater pollution potential of nonpoint source pesticides. A conceptual relationship is presented that relates seasonally averaged groundwater recharge to soil properties and depths to the water table. The analy...

GIS applications to wilderness management: potential uses and limitations

Treesearch

Peter Landres; David R. Spildie; Lloyd P. Queen

2001-01-01

Geographic Information Systems (GIS) are increasingly being used in all areas of natural resource management. This paper first presents a brief primer on GIS, and then discusses potential applications of GIS to wilderness management in the areas of inventorying, monitoring, analysis, planning, and communication. Outlined are the limitations and pitfalls that could...

The Potential of NovaNET Communications for Education and Instruction.

ERIC Educational Resources Information Center

Steinberg, Esther R.

Intended to suggest ways of implementing the potential of NovaNet beyond its current applications, this report begins with an overview of current educational applications of telecommunications systems. It is noted that NovaNET is not only a successful computer system for presenting instructional courseware, but that it also supports…

Computational Nanotechnology of Molecular Materials, Electronics and Machines

NASA Technical Reports Server (NTRS)

Srivastava, D.; Biegel, Bryan A. (Technical Monitor)

2002-01-01

This viewgraph presentation covers carbon nanotubes, their characteristics, and their potential future applications. The presentation include predictions on the development of nanostructures and their applications, the thermal characteristics of carbon nanotubes, mechano-chemical effects upon carbon nanotubes, molecular electronics, and models for possible future nanostructure devices. The presentation also proposes a neural model for signal processing.

Fiber Bragg grating applications in biomechanics

NASA Astrophysics Data System (ADS)

Kalinowski, Hypolito José

2008-04-01

Fibre Bragg gratings are promising sensors for medical and bioengineering applications, mainly because of their small dimensions and chemical inertness. Although few examples of such applications are published up to date, we present results that show the expected potential for FBG sensor applications in biomechanical engineering.

Graphene-MoS2 Heterojunctions for High-Speed Opto-electronics

NASA Astrophysics Data System (ADS)

Horng, Jason; Wang, Alex; Wang, Danqing; Li, Alexander Shengzhi; Wang, Feng

Heterostructures consisting of two-dimensional materials has drawn significant attention in different research fields owning to their novel electronic states and potential applications. Transmitting information with transition metal dichalcogenides(TMDC) electro-optical modulator switch interconnect is of great interest for technological applications. However, their high-speed applications have been slowed by their intrinsically high resistivity as well as the difficulties in making optimized metal contacts. Here, we present a new strategy by using graphene as a tunable contact to two-dimensional semiconductors to explore possible applications in high-speed opto-electronics. We will present an optical study to provide better understanding of band alignment in graphene/MoS2 heterostructures and a demonstration of high-speed opto-electronics based on these heterostructures. The result shows the new scheme could have potential in both opto-modulators and optical sensing applications.

UNCERTAINTY IN LEACHING POTENTIAL OF NONPOINT SOURCE POLLUTANTS WITH APPLICATION TO A GIS

EPA Science Inventory

This paper presents a stochastic framework for the assessment of groundwater pollution potential of nonpoint source pesticides. A conceptual relationship is presented that relates seasonally averaged groundwater recharge to soil properties and depths to the water table. The analy...

Novel Three-Dimensional Vertical Interconnect Technology for Microwave and RF Applications

NASA Technical Reports Server (NTRS)

Goverdhanam, Kavita; Simons, Rainee N.; Katehi, Linda P. B.

1999-01-01

In this paper, novel 3D interconnects suitable for applications in microwave and RF integrated circuit technology have been presented. The interconnect fabrication process and design details are presented. In addition, measured and numerically modeled results of the performance of the interconnects have been shown. The results indicate that the proposed technology has tremendous potential applications in integrated circuit technology. C,

Photovoltaic highway applications: Assessment of the near-term market

NASA Technical Reports Server (NTRS)

Rosenblum, L.; Scudder, L. R.; Bifano, W. J.; Poley, W. A.

1977-01-01

A preliminary assessment of the near-term market for photovoltaic highway applications is presented. Among the potential users, two market sectors are considered: government and commercial. Within these sectors, two possible application areas, signs and motorist aids, are discussed. Based on judgemental information, obtained by a brief survey of representatives of the two user sectors, the government sector appears more amenable to the introduction of photovoltaic power sources for highway applications in the near-term. However, considerable interest and potential opportunities were also found to exist in the commercial sector. Further studies to quantify the market for highway applications appear warranted.

Orbiting Sample Capture and Orientation Technologies for Potential Mars Sample Return

NASA Astrophysics Data System (ADS)

Younse, P.; Adajian, R.; Dolci, M.; Ohta, P.; Olds, E.; Lalla, K.; Strahle, J. W.

2018-04-01

Technologies applicable to a potential Mars Sample Return Orbiter for orbiting sample container capture and orientation are presented, as well as an integrated MArs CApture and ReOrientation for a potential NExt Mars Orbiter (MACARONE) concept.

Process heat in California: Applications and potential for solar energy in the industrial, agricultural and commercial sectors

NASA Technical Reports Server (NTRS)

Barbieri, R. H.; Bartera, R. E.; Davis, E. S.; Hlavka, G. E.; Pivirotto, D. S.; Yanow, G.

1978-01-01

A summary of the results of a survey of potential applications of solar energy for supplying process heat requirements in the industrial, agricultural, and commercial sectors of California is presented. Technical, economic, and institutional characteristics of the three sectors are examined. Specific applications for solar energy are then discussed. Finally, implications for California energy policy are discussed along with recommendations for possible actions by the State of California.

Rocket engine numerical simulator

NASA Technical Reports Server (NTRS)

Davidian, Ken

1993-01-01

The topics are presented in viewgraph form and include the following: a rocket engine numerical simulator (RENS) definition; objectives; justification; approach; potential applications; potential users; RENS work flowchart; RENS prototype; and conclusion.

Exploiting Dark Information Resources to Create New Value Added Services to Study Earth Science Phenomena

NASA Technical Reports Server (NTRS)

Ramachandran, Rahul; Maskey, Manil; Li, Xiang; Bugbee, Kaylin

2017-01-01

This paper presents two research applications exploiting unused metadata resources in novel ways to aid data discovery and exploration capabilities. The results based on the experiments are encouraging and each application has the potential to serve as a useful standalone component or service in a data system. There were also some interesting lessons learned while designing the two applications and these are presented next.

A Future with Hybrid Electric Propulsion Systems: A NASA Perspective

NASA Technical Reports Server (NTRS)

DelRosario, Ruben

2014-01-01

The presentation highlights a NASA perspective on Hybrid Electric Propulsion Systems for aeronautical applications. Discussed are results from NASA Advance Concepts Study for Aircraft Entering service in 2030 and beyond and the potential use of hybrid electric propulsion systems as a potential solution to the requirements for energy efficiency and environmental compatibility. Current progress and notional potential NASA research plans are presented.

Application of volume rendering technique (VRT) for musculoskeletal imaging.

PubMed

Darecki, Rafał

2002-10-30

A review of the applications of volume rendering technique in musculoskeletal three-dimensional imaging from CT data. General features, potential and indications for applying the method are presented.

Application of advanced technologies to future military transports

NASA Technical Reports Server (NTRS)

Clark, Rodney L.; Lange, Roy H.; Wagner, Richard D.

1990-01-01

Long range military transport technologies are addressed with emphasis of defining the potential benefits of the hybrid laminar flow control (HLFC) concept currently being flight tested. Results of a 1990's global range transport study are presented showing the expected payoff from application of advanced technologies. Technology forecast for military transports is also presented.

Selection and Classification Using a Forecast Applicant Pool.

ERIC Educational Resources Information Center

Hendrix, William H.

The document presents a forecast model of the future Air Force applicant pool. By forecasting applicants' quality (means and standard deviations of aptitude scores) and quantity (total number of applicants), a potential enlistee could be compared to the forecasted pool. The data used to develop the model consisted of means, standard deviation, and…

Potential Nano-Enabled Environmental Applications for Radionuclides

EPA Pesticide Factsheets

This document provides information about nanotechnology materials and processes that may be applicable when cleaning up radioactively contaminated sites or materials, and presents a snapshot of lessons learned in nano-science and engineering.

Workshop on Fielded Applications of Machine Learning

DTIC Science & Technology

1994-05-11

This report summaries the talks presented at the Workshop on Fielded Applications of Machine Learning , and draws some initial conclusions about the state of machine learning and its potential for solving real-world problems.

Rocket engine numerical simulation

NASA Astrophysics Data System (ADS)

Davidian, Ken

1993-12-01

The topics are presented in view graph form and include the following: a definition of the rocket engine numerical simulator (RENS); objectives; justification; approach; potential applications; potential users; RENS work flowchart; RENS prototype; and conclusions.

Rocket engine numerical simulation

NASA Technical Reports Server (NTRS)

Davidian, Ken

1993-01-01

The topics are presented in view graph form and include the following: a definition of the rocket engine numerical simulator (RENS); objectives; justification; approach; potential applications; potential users; RENS work flowchart; RENS prototype; and conclusions.

Commercial Off-The-Shelf (COTS) Electronics Reliability for Space Applications

NASA Technical Reports Server (NTRS)

Pellish, Jonathan

2018-01-01

This presentation describes the accelerating use of Commercial off the Shelf (COTS) parts in space applications. Component reliability and threats in the context of the mission, environment, application, and lifetime. Provides overview of traditional approaches applied to COTS parts in flight applications, and shows challenges and potential paths forward for COTS systems in flight applications it's all about data!

Study terrestrial applications of solar cell powered systems

NASA Technical Reports Server (NTRS)

Ravin, J. W.

1973-01-01

Terrestrial applications of solar cells and design systems are considered for those applications that show the most promise for becoming practical and accepted by users within the next five years. The study includes the definition, categorization, evaluation and screening of the most attractive potential terrestrial applications for solar cells. Potential markets are initially grouped and categorized in a general sense and are weighted in priority by their business volume, present and future. From a categorized list including marine, transportation, security, communication, meteorological and others, 66 potential solar cell applications have been cataloged. A methodology was formulated to include the criteria for evaluation and screening. The evaluation process covers all parts and components of the complete system required for each application and gives consideration to all factors, such as engineering, economic, production, marketing and other factors that may have an influence on the acceptance of the system.

Advice and guidance on the admissions process to UK dental schools.

PubMed

McAndrew, Robert; Salem-Rahemi, Morva

2013-03-01

Students looking to read dentistry can be overwhelmed by the information and requirements presented to them by dental schools, career advisors and the printed literature. In the UK, there are currently 16 dental schools which provide a dentistry degree. While there are variations in the specific aspects of the dental courses at each school, there are common principles and generic application requirements that apply. This paper provides a guide to facilitate applications and inform potential students, career advisors and dentists. The information presented has been gathered from UK dental school websites and university prospectuses and corroborated through contact with university admissions offices. This paper is relevant to dental practitioners who are often asked to provide advice on applications to dental schools by potential students.

Potential benefits of superconductivity to transportation in the United States

NASA Astrophysics Data System (ADS)

Rote, Donald M.; Johnson, Larry R.

Research in U.S. transportation applications of superconductors is strongly motivated by a number of potential national benefits. These include the reduction of dependence on petroleum-based fuels, energy savings, substantially reduced air and noise pollution, increased customer convenience, and reduced maintenance costs. Current transportation technology offers little flexibility to switch to alternative fuels, and efforts to achieve the other benefits are confounded by growing congestion at airports and on urban roadways. A program has been undertaken to identify possible applications of the emerging superconducting applications to transportation and to evaluate potential national benefits. The current phase of the program will select the most promising applications for a more detailed subsequent study. Transportation modes being examined include highway and industrial vehicles, as well as rail, sea, air transport and pipelines. Three strategies are being considered: (1) replacing present components with those employing superconductors, (2) substituting new combinations of components or systems for present systems, and (3) developing completely new technologies. Distinctions are made between low-, medium-, and near-room-temperature superconductors. The most promising applications include magnetically levitated passenger and freight vehicles; replacement of drive systems in locomotives, self-propelled rail cars, and ships; and electric vehicles inductively coupled to electrified roadways.

Digital video applications in radiologic education: theory, technique, and applications.

PubMed

Hennessey, J G; Fishman, E K; Ney, D R

1994-05-01

Computer-assisted instruction (CAI) has great potential in medical education. The recent explosion of multimedia platforms provides an environment for the seemless integration of text, images, and sound into a single program. This article discusses the role of digital video in the current educational environment as well as its future potential. An indepth review of the technical decisions of this new technology is also presented.

MIPs as Tools in Environmental Biotechnology.

PubMed

Mattiasson, Bo

2015-01-01

Molecular imprints are potentially fantastic constructions. They are selective, robust, and nonbiodegradable if produced from stable polymers. A range of different applications has been presented, everything from separation of enantiomers, via adsorbents for sample preparation before analysis to applications in wastewater treatment. This chapter deals with molecularly imprinted polymers (MIPs) as tools in environmental biotechnology, a field that has the potential to become very important in the future.

Investigation of short cavity CRDS noise terms by optical correlation

NASA Astrophysics Data System (ADS)

Griffin, Steven T.; Fathi, Jason

2013-05-01

Cavity Ring Down Spectroscopy (CRDS) has been identified as having significant potential for Department of Defense security and sensing applications. Significant factors in the development of new sensor architectures are portability, robustness and economy. A significant factor in new CRDS sensor architectures is cavity length. Prior publication has examined the role of cavity length in sensing modality both from the standpoint of the system's design and the identification of potential difficulties presented by novel approaches. Two of interest here are new noise terms that have been designated turbulence-like and speckle-like in prior publication. In the prior publication the theoretical and some empirical data was presented. This presentation addresses the automation of the experimental apparatus, new data analysis, and implications regarding the significance of the two noise terms. This is accomplished through an Analog-to- Digital Conversion (ADC) from the output of a custom designed optical correlator. Details of the unique application of the developed instrument and implications for short cavity (portable) CRDS applications are presented.

Applications Of Graphite Fluoride Fibers In Outer Space

NASA Technical Reports Server (NTRS)

Hung, Ching-Cheng; Long, Martin; Dever, Therese

1993-01-01

Report characterizes graphite fluoride fibers made from commercially available graphitized carbon fibers and discusses some potential applications of graphite fluoride fibers in outer space. Applications include heat-sinking printed-circuit boards, solar concentrators, and absorption of radar waves. Other applications based on exploitation of increased resistance to degradation by atomic oxygen, present in low orbits around Earth.

Microgravity science and applications projects and payloads

NASA Technical Reports Server (NTRS)

Crouch, R. K.

1987-01-01

An overview of work conducted by the Microgravity Science and Applications Division of NASA is presented. The goals of the program are the development and implementation of a reduced-gravity research, science and applications program, exploitation of space for human benefits, and the application of reduced gravity research for the development of advanced technologies. Space research of fluid dynamics and mass transport phenomena is discussed and the facilities available for reduced gravity experiments are presented. A program for improving communication with the science and applications communities and the potential use of the Space Station for microgravity research are also examined.

Potential applications of expert systems and operations research to space station logistics functions

NASA Technical Reports Server (NTRS)

Lippiatt, Thomas F.; Waterman, Donald

1985-01-01

The applicability of operations research, artificial intelligence, and expert systems to logistics problems for the space station were assessed. Promising application areas were identified for space station logistics. A needs assessment is presented and a specific course of action in each area is suggested.

Using Solution-Focused Applications for Transitional Coping of Workplace Survivors

ERIC Educational Resources Information Center

Germain, Marie-Line; Palamara, Sherry A.

2007-01-01

Solution-focused applications are proposed to assist survivor employees to return to workplace homeostasis after co-workers voluntarily or involuntarily leave the organization. A model for transitional coping is presented as well as a potential case study illustrating the application of the model. Implications for the theory, practice, and…

MELODI: Mining Enriched Literature Objects to Derive Intermediates

PubMed Central

Elsworth, Benjamin; Dawe, Karen; Vincent, Emma E; Langdon, Ryan; Lynch, Brigid M; Martin, Richard M; Relton, Caroline; Higgins, Julian P T; Gaunt, Tom R

2018-01-01

Abstract Background The scientific literature contains a wealth of information from different fields on potential disease mechanisms. However, identifying and prioritizing mechanisms for further analytical evaluation presents enormous challenges in terms of the quantity and diversity of published research. The application of data mining approaches to the literature offers the potential to identify and prioritize mechanisms for more focused and detailed analysis. Methods Here we present MELODI, a literature mining platform that can identify mechanistic pathways between any two biomedical concepts. Results Two case studies demonstrate the potential uses of MELODI and how it can generate hypotheses for further investigation. First, an analysis of ETS-related gene ERG and prostate cancer derives the intermediate transcription factor SP1, recently confirmed to be physically interacting with ERG. Second, examining the relationship between a new potential risk factor for pancreatic cancer identifies possible mechanistic insights which can be studied in vitro. Conclusions We have demonstrated the possible applications of MELODI, including two case studies. MELODI has been implemented as a Python/Django web application, and is freely available to use at [www.melodi.biocompute.org.uk]. PMID:29342271

Fly ashes from coal and petroleum coke combustion: current and innovative potential applications.

PubMed

González, Aixa; Navia, Rodrigo; Moreno, Natalia

2009-12-01

Coal fly ashes (CFA) are generated in large amounts worldwide. Current combustion technologies allow the burning of fuels with high sulfur content such as petroleum coke, generating non-CFA, such as petroleum coke fly ash (PCFA), mainly from fluidized bed combustion processes. The disposal of CFA and PCFA fly ashes can have severe impacts in the environment such as a potential groundwater contamination by the leaching of heavy metals and/or particulate matter emissions; making it necessary to treat or reuse them. At present CFA are utilized in several applications fields such as cement and concrete production, agriculture and soil stabilization. However, their reuse is restricted by the quality parameters of the end-product or requirements defined by the production process. Therefore, secondary material markets can use a limited amount of CFA, which implies the necessity of new markets for the unused CFA. Some potential future utilization options reviewed herein are zeolite synthesis and valuable metals extraction. In comparison to CFA, PCFA are characterized by a high Ca content, suggesting a possible use as neutralizers of acid wastewaters from mining operations, opening a new potential application area for PCFA that could solve contamination problems in emergent and mining countries such as Chile. However, this potential application may be limited by PCFA heavy metals leaching, mainly V and Ni, which are present in PCFA in high concentrations.

APPLICATIONS OF ELECTROCHEMICAL IMMUNOSENSORS TO ENVIRONMENTAL MONITORING

EPA Science Inventory

This paper discusses basic electrochemical immunoassay technology. Factors limiting the practical application of antibodies to anlaytical problems are also presented. It addresses the potential use of immunoassay methods based on electrochemical detection for the analysis of env...

Applicability of ISO 16697 Data to Spacecraft Fire Fighting Strategies

NASA Technical Reports Server (NTRS)

Hirsch, David B.; Beeson, Harold D.

2012-01-01

Presentation Agenda: (1) Selected variables affecting oxygen consumption during spacecraft fires, (2) General overview of ISO 16697, (3) Estimated amounts of material consumed during combustion in typical ISS enclosures, (4) Discussion on potential applications.

Robotic instrumentation: Evolution and microsurgical applications

PubMed Central

Parekattil, Sijo J.; Moran, Michael E.

2010-01-01

This article presents a review of the history and evolution of robotic instrumentation and its applications in urology. A timeline for the evolution of robotic instrumentation is presented to better facilitate an understanding of our current-day applications. Some new directions including robotic microsurgical applications (robotic assisted denervation of the spermatic cord for chronic orchialgia and robotic assisted vasectomy reversal) are presented. There is a paucity of prospective comparative effectiveness studies for a number of robotic applications. However, right or wrong, human nature has always led to our infatuation with the concept of using tools to meet our needs. This chapter is a brief tribute to where we have come from and where we may be potentially heading in the field of robotic assisted urologic surgery. PMID:21116362

Artificial Intelligence and Expert Systems: Will They Change the Library? Papers Presented at the Annual Clinic on Library Applications of Data Processing (27th, Urbana, Illinois, March 25-27, 1990). Illinois, March 25-27, 1990).

ERIC Educational Resources Information Center

Lancaster, F. W., Ed.; Smith, Linda C., Ed.

Some of the 12 conference papers presented in this proceedings focus on the present and potential capabilities of artificial intelligence and expert systems as they relate to a wide range of library applications, including descriptive cataloging, technical services, collection development, subject indexing, reference services, database searching,…

Potential Applications of Nanocellulose-Containing Materials in the Biomedical Field

PubMed Central

Halib, Nadia; Perrone, Francesca; Dapas, Barbara; Farra, Rossella; Abrami, Michela; Chiarappa, Gianluca; Forte, Giancarlo; Zanconati, Fabrizio; Pozzato, Gabriele; Murena, Luigi; Fiotti, Nicola; Lapasin, Romano; Cansolino, Laura; Grassi, Gabriele

2017-01-01

Because of its high biocompatibility, bio-degradability, low-cost and easy availability, cellulose finds application in disparate areas of research. Here we focus our attention on the most recent and attractive potential applications of cellulose in the biomedical field. We first describe the chemical/structural composition of cellulose fibers, the cellulose sources/features and cellulose chemical modifications employed to improve its properties. We then move to the description of cellulose potential applications in biomedicine. In this field, cellulose is most considered in recent research in the form of nano-sized particle, i.e., nanofiber cellulose (NFC) or cellulose nanocrystal (CNC). NFC is obtained from cellulose via chemical and mechanical methods. CNC can be obtained from macroscopic or microscopic forms of cellulose following strong acid hydrolysis. NFC and CNC are used for several reasons including the mechanical properties, the extended surface area and the low toxicity. Here we present some potential applications of nano-sized cellulose in the fields of wound healing, bone-cartilage regeneration, dental application and different human diseases including cancer. To witness the close proximity of nano-sized cellulose to the practical biomedical use, examples of recent clinical trials are also reported. Altogether, the described examples strongly support the enormous application potential of nano-sized cellulose in the biomedical field. PMID:28825682

Potential perils of peri-Pokémon perambulation: the dark reality of augmented reality?

PubMed Central

Joseph, Bellal; Armstrong, David G.

2016-01-01

Recently, the layering of augmented reality information on top of smartphone applications has created unprecedented user engagement and popularity. One augmented reality-based entertainment application, Pokémon Go (Pokémon Company, Tokyo, Japan) has become the most rapidly downloaded in history. This technology holds tremendous promise to promote ambulatory activity. However, there exists the obvious potential for distraction-related morbidity. We report two cases, presenting simultaneously to our trauma center, with injuries sustained secondary to gameplay with this augmented reality-based application. PMID:27713831

Potential perils of peri-Pokémon perambulation: the dark reality of augmented reality?

PubMed

Joseph, Bellal; Armstrong, David G

2016-10-01

Recently, the layering of augmented reality information on top of smartphone applications has created unprecedented user engagement and popularity. One augmented reality-based entertainment application, Pokémon Go (Pokémon Company, Tokyo, Japan) has become the most rapidly downloaded in history. This technology holds tremendous promise to promote ambulatory activity. However, there exists the obvious potential for distraction-related morbidity. We report two cases, presenting simultaneously to our trauma center, with injuries sustained secondary to gameplay with this augmented reality-based application.

Augmented reality application for industrial non-destructive inspection training

NASA Astrophysics Data System (ADS)

Amza, Catalin Gheorghe; Zapciu, Aurelian; Teodorescu, Octav

2018-02-01

Such a technology - Augmented Reality (AR) has great potential of use, especially for training purposes of new operators on using expensive equipment. In this context, the paper presents an augmented reality training system developed for phased-array ultrasonic non-destructive testing (NDT) equipment. The application has been developed using Unity 5.6.0 game-engine platform integrated with Vuforia sdk toolkit for devices with Android operating system. The test results performed by several NDT operators showed good results, thus proving the potential of using the application in the industrial field.

Software for Intelligent System Health Management

NASA Technical Reports Server (NTRS)

Trevino, Luis C.

2004-01-01

This viewgraph presentation describes the characteristics and advantages of autonomy and artificial intelligence in systems health monitoring. The presentation lists technologies relevant to Intelligent System Health Management (ISHM), and some potential applications.

New developments in ophthalmic applications of ultrafast lasers

NASA Astrophysics Data System (ADS)

Spooner, Greg J. R.; Juhasz, Tibor; Ratkay-Traub, Imola; Djotyan, Gagik P.; Horvath, Christopher; Sacks, Zachary S.; Marre, Gabrielle; Miller, Doug L.; Williams, A. R.; Kurtz, Ron M.

2000-05-01

The eye is potentially an ideal target for high precision surgical procedures utilizing ultrafast lasers. We present progress on corneal applications now being tested in humans and proof of concept ex vivo demonstrations of new applications in the sclera and lens. Two corneal refractive procedures were tested in partially sighted human eyes: creation of corneal flaps prior to excimer ablation (Femto- LASIK) and creation of corneal channels and entry cuts for placement of intracorneal ring segments (Femto-ICRS). For both procedures, results were comparable to standard treatments, with the potential for improved safety, accuracy and reproducibility. For scleral applications, we evaluated the potential of femtosecond laser glaucoma surgery by demonstrating resections in ex vivo human sclera using dehydrating agents to induce tissue transparency. For lens applications, we demonstrate in an ex vivo model the use of photodisruptively-nucleated ultrasonic cavitation for local and non-invasive tissue interaction.

RECENT ENHANCEMENTS TO THE DIETARY EXPOSURE POTENTIAL MODEL

EPA Science Inventory

Presentation describes recent enhancements & new applications of the Dietary Exposure Potential Model (DEPM), a model developed to assist in design & interpretation of dietary exposure measurements. Model is an interactive system that provides dietary exposure estimates using dat...

Using the World Wide Web: Applications for Marketing Educators.

ERIC Educational Resources Information Center

Stull, William A.; And Others

1996-01-01

This article introduces potential uses of the World Wide Web for marketing education, presents tips for navigating the web, and provides a sample of useful applications. Also provides suggestions for monitoring student use of the web. (JOW)

Reactive Power Compensating System.

DOEpatents

Williams, Timothy J.; El-Sharkawi, Mohamed A.; Venkata, Subrahmanyam S.

1985-01-04

The circuit was designed for the specific application of wind-driven induction generators. It has great potential for application in any situation where a varying reactive power load is present, such as with induction motors or generators, or for transmission network compensation.

Out-of-equilibrium body potential measurements in pseudo-MOSFET for sensing applications

NASA Astrophysics Data System (ADS)

Benea, Licinius; Bawedin, Maryline; Delacour, Cécile; Ionica, Irina

2018-05-01

The aim of this paper is to present the out-of-equilibrium body potential behaviour in the Ψ-MOSFET configuration. Consistent measurements in this experimental setup succeeded in providing a substantial understanding of its characteristics in the depletion region. The final objective of this work is to envision this new measurement technique for biochemical sensor applications. Among its advantages, the most important are its simplicity, the good sensitivity, the measurement of a potential instead of a current and the low bias needed for detection compared to the conventional drain current measurements.

Market projections of cellulose nanomaterial-enabled products- Part 1: Applications

Treesearch

Jo Anne Shatkin; Theodore H. Wegner; E.M. (Ted) Bilek; John Cowie

2014-01-01

Nanocellulose provides a new materials platform for the sustainable production of high-performance nano-enabled products in an array of applications. In this paper, potential applications for cellulose nanomaterials are identified as the first step toward estimating market volume. The overall study, presented in two parts, estimates market volume on the basis of...

Dual ion beam processed diamondlike films for industrial applications

NASA Technical Reports Server (NTRS)

Mirtich, M. J.; Kussmaul, M. T.; Banks, B. A.; Sovey, J. S.

1991-01-01

Single and dual beam ion source systems are used to generate amorphous diamondlike carbon (DLC) films, which were evaluated for a variety of applications including protective coatings on transmitting materials, power electronics as insulated gates and corrosion resistant barriers. A list of the desirable properties of DLC films along with potential applications are presented.

Applications of KPFM-Based Approaches for Surface Potential and Electrochemical Measurements in Liquid

DOE Office of Scientific and Technical Information (OSTI.GOV)

Collins, Liam F.; Weber, Stefan A. L.; Rodriguez, Brian

Kelvin probe force microscopy (KPFM) has been widely used to map nanoscale surface potentials of materials in ambient and ultra-high vacuum environments. However, to study and ultimately understand charge-related processes, e.g., in biological systems or to further improve energy storage devices such as electrochemical batteries, nanoscale surface potential measurements in liquid environments are required. Here, we describe the various implementations of KPFM-based approaches for measuring surface potentials in liquid environments. We provide practical guidelines for surface potential measurements and describe what other information can be obtained. Finally, we discuss potential applications and limitations of existing approaches and present possible solutionsmore » for the successful implementation of liquid KPFM.« less

Nanotechnology for Site Remediation: Fact Sheet

EPA Pesticide Factsheets

This fact sheet presents a snapshot of nanotechnology and its current uses in remediation. It presents information to help site project managers understand the potential applications of this group of technologies at their sites.

Potential Uses and Inherent Challenges of Using Genome-Scale Sequencing to Augment Current Newborn Screening.

PubMed

Berg, Jonathan S; Powell, Cynthia M

2015-10-05

Since newborn screening (NBS) began in the 1960s, technological advances have enabled its expansion to include an increasing number of disorders. Recent developments now make it possible to sequence an infant's genome relatively quickly and economically. Clinical application of whole-exome and whole-genome sequencing is expanding at a rapid pace but presents many challenges. Its utility in NBS has yet to be demonstrated and its application in the pediatric population requires examination, not only for potential clinical benefits, but also for the unique ethical challenges it presents. Copyright © 2015 Cold Spring Harbor Laboratory Press; all rights reserved.

BASINs and WEPP Climate Assessment Tools (CAT): Case ...

EPA Pesticide Factsheets

EPA announced the release of the final report, BASINs and WEPP Climate Assessment Tools (CAT): Case Study Guide to Potential Applications. This report supports application of two recently developed water modeling tools, the Better Assessment Science Integrating point & Non-point Sources (BASINS) and the Water Erosion Prediction Project Climate Assessment Tool (WEPPCAT). The report presents a series of short case studies designed to illustrate the capabilities of these tools for conducting scenario based assessments of the potential effects of climate change on streamflow and water quality. This report presents a series of short, illustrative case studies using the BASINS and WEPP climate assessment tools.

Bio-analytical applications of microbial fuel cell-based biosensors for onsite water quality monitoring.

PubMed

ElMekawy, A; Hegab, H M; Pant, D; Saint, C P

2018-01-01

Globally, sustainable provision of high-quality safe water is a major challenge of the 21st century. Various chemical and biological monitoring analytics are presently utilized to guarantee the availability of high-quality water. However, these techniques still face some challenges including high costs, complex design and onsite and online limitations. The recent technology of using microbial fuel cell (MFC)-based biosensors holds outstanding potential for the rapid and real-time monitoring of water source quality. MFCs have the advantages of simplicity in design and efficiency for onsite sensing. Even though some sensing applications of MFCs were previously studied, e.g. biochemical oxygen demand sensor, recently numerous research groups around the world have presented new practical applications of this technique, which combine multidisciplinary scientific knowledge in materials science, microbiology and electrochemistry fields. This review presents the most updated research on the utilization of MFCs as potential biosensors for monitoring water quality and considers the range of potentially toxic analytes that have so far been detected using this methodology. The advantages of MFCs over established technology are also considered as well as future work required to establish their routine use. © 2017 The Society for Applied Microbiology.

High-Performance Liquid Chromatography-Mass Spectrometry.

ERIC Educational Resources Information Center

Vestal, Marvin L.

1984-01-01

Reviews techniques for online coupling of high-performance liquid chromatography with mass spectrometry, emphasizing those suitable for application to nonvolatile samples. Also summarizes the present status, strengths, and weaknesses of various techniques and discusses potential applications of recently developed techniques for combined liquid…

Handbook of data on selected engine components for solar thermal applications

NASA Technical Reports Server (NTRS)

1979-01-01

A data base on developed and commercially available power conversion system components for Rankine and Brayton cycle engines, which have potential application to solar thermal power-generating systems is presented. The status of the Stirling engine is discussed.

Intelligent Computational Systems. Opening Remarks: CFD Application Process Workshop

NASA Technical Reports Server (NTRS)

VanDalsem, William R.

1994-01-01

This discussion will include a short review of the challenges that must be overcome if computational physics technology is to have a larger impact on the design cycles of U.S. aerospace companies. Some of the potential solutions to these challenges may come from the information sciences fields. A few examples of potential computational physics/information sciences synergy will be presented, as motivation and inspiration for the Improving The CFD Applications Process Workshop.

Beyond Bitcoin: Potential Applications of Blockchain Technology in Dermatology.

PubMed

Tung, J K; Nambudiri, V E

2018-06-26

Since its initial popularization in 2008 as the underpinnings of the digital currency Bitcoin, blockchain has seen its implications spread beyond the financial industry. 1 The field of dermatology presents promising potential applications for this burgeoning technology. Blockchain facilitates communication on a peer-to-peer platform with users sharing data directly with each other (Figure). This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Boundary elements; Proceedings of the Fifth International Conference, Hiroshima, Japan, November 8-11, 1983

NASA Astrophysics Data System (ADS)

Brebbia, C. A.; Futagami, T.; Tanaka, M.

The boundary-element method (BEM) in computational fluid and solid mechanics is examined in reviews and reports of theoretical studies and practical applications. Topics presented include the fundamental mathematical principles of BEMs, potential problems, EM-field problems, heat transfer, potential-wave problems, fluid flow, elasticity problems, fracture mechanics, plates and shells, inelastic problems, geomechanics, dynamics, industrial applications of BEMs, optimization methods based on the BEM, numerical techniques, and coupling.

Image processing applications: From particle physics to society

NASA Astrophysics Data System (ADS)

Sotiropoulou, C.-L.; Luciano, P.; Gkaitatzis, S.; Citraro, S.; Giannetti, P.; Dell'Orso, M.

2017-01-01

We present an embedded system for extremely efficient real-time pattern recognition execution, enabling technological advancements with both scientific and social impact. It is a compact, fast, low consumption processing unit (PU) based on a combination of Field Programmable Gate Arrays (FPGAs) and the full custom associative memory chip. The PU has been developed for real time tracking in particle physics experiments, but delivers flexible features for potential application in a wide range of fields. It has been proposed to be used in accelerated pattern matching execution for Magnetic Resonance Fingerprinting (biomedical applications), in real time detection of space debris trails in astronomical images (space applications) and in brain emulation for image processing (cognitive image processing). We illustrate the potentiality of the PU for the new applications.

The development of a host potential index and its postharvest application to the spotted wing drosophila, Drosophila suzukii (Diptera: Drosophilidae)

USDA-ARS?s Scientific Manuscript database

Novel methodology is presented for indexing the relative potential of hosts to function as resources. Results from studies examining host selection, utilization, and physiological development of the organism resourcing the host were combined and quantitatively related via a Host Potential Index (HPI...

Multidimensional Approach to Detecting Creative Potential in Managers

ERIC Educational Resources Information Center

Caroff, Xavier; Lubart, Todd

2012-01-01

Creativity is increasingly recognized as a key component to success in the workplace. This article explores the detection of creative potential in managers. In a first part, creative potential is defined and a multivariate approach concerning the psychological resources for creativity is presented. Then, in a second part, an application of this…

Carbon nanotube: A review on its mechanical properties and application in aerospace industry

NASA Astrophysics Data System (ADS)

Raunika, A.; Aravind Raj, S.; Jayakrishna, K.; Sultan, M. T. H.

2017-12-01

Carbon nanotube (CNT) is a prominent material that has good potential to be used in numerous aerospace applications. This paper presents a review about CNT on its various aspects such as fabrication methods, mechanical properties and applications in aerospace. The evolution of CNT is discussed to its recent applications. The aim of this review article is to highlight the recent advancements in CNT and its possible applications in aerospace.

3D Surface Reconstruction and Automatic Camera Calibration

NASA Technical Reports Server (NTRS)

Jalobeanu, Andre

2004-01-01

Illustrations in this view-graph presentation are presented on a Bayesian approach to 3D surface reconstruction and camera calibration.Existing methods, surface analysis and modeling,preliminary surface reconstruction results, and potential applications are addressed.

Teaching with Secondary Data.

ERIC Educational Resources Information Center

Sobol, Jeff

1981-01-01

Presents a general overview of the use of secondary data in teaching sociology on the college level. Topics discussed include potential for additional applications, sources which constitute secondary data, reasons for using secondary data in the classroom, information about computing, and potential problems. (Author/DB)

Aerospace management techniques: Commercial and governmental applications

NASA Technical Reports Server (NTRS)

Milliken, J. G.; Morrison, E. J.

1971-01-01

A guidebook for managers and administrators is presented as a source of useful information on new management methods in business, industry, and government. The major topics discussed include: actual and potential applications of aerospace management techniques to commercial and governmental organizations; aerospace management techniques and their use within the aerospace sector; and the aerospace sector's application of innovative management techniques.

Syntheses of the current model applications for managing water and needs for experimental data and model improvements to enhance these applications

USDA-ARS?s Scientific Manuscript database

This volume of the Advances in Agricultural Systems Modeling series presents 14 different case studies of model applications to help make the best use of limited water in agriculture. These examples show that models have tremendous potential and value in enhancing site-specific water management for ...

Future of synthetic aperture radar

NASA Technical Reports Server (NTRS)

Barath, F. T.

1978-01-01

The present status of the applications of Synthetic Aperture Radars (SARs) is reviewed, and the technology state-of-the art as represented by the Seasat-A and SIR-A SARs examined. The potential of SAR applications, and the near- and longer-term technology trends are assessed.

Recent applications of the transonic wing analysis computer code, TWING

NASA Technical Reports Server (NTRS)

Subramanian, N. R.; Holst, T. L.; Thomas, S. D.

1982-01-01

An evaluation of the transonic-wing-analysis computer code TWING is given. TWING utilizes a fully implicit approximate factorization iteration scheme to solve the full potential equation in conservative form. A numerical elliptic-solver grid-generation scheme is used to generate the required finite-difference mesh. Several wing configurations were analyzed, and the limits of applicability of this code was evaluated. Comparisons of computed results were made with available experimental data. Results indicate that the code is robust, accurate (when significant viscous effects are not present), and efficient. TWING generally produces solutions an order of magnitude faster than other conservative full potential codes using successive-line overrelaxation. The present method is applicable to a wide range of isolated wing configurations including high-aspect-ratio transport wings and low-aspect-ratio, high-sweep, fighter configurations.

A Short Introduction to Arterial Spin Labeling and its Application to Flow Territory Mapping.

PubMed

Lindner, T; Helle, M; Jansen, O

2015-10-01

Arterial spin labeling (ASL) is an emerging method for the assessment of perfusion in various diseases of the brain. In ASL, the magnetization of arterial blood water spins is manipulated in a complete non-invasive way before flowing into the tissue of interest. This allows absolute quantification of cerebral blood flow, thereby, presenting an alternative to contrast-enhanced methods based on computed tomography or magnetic resonance imaging. Furthermore, its potential application for flow territory mapping can provide additional information of the individual configuration of intracerebral blood flow. This article gives a brief overview of the basic ASL methodology and its approaches to image individual perfusion territories. Additionally, the utilization of ASL in a variety of cerebrovascular diseases is presented to provide examples of potential applications of (territorial) ASL in clinical routine.

MELODI: Mining Enriched Literature Objects to Derive Intermediates.

PubMed

Elsworth, Benjamin; Dawe, Karen; Vincent, Emma E; Langdon, Ryan; Lynch, Brigid M; Martin, Richard M; Relton, Caroline; Higgins, Julian P T; Gaunt, Tom R

2018-01-12

The scientific literature contains a wealth of information from different fields on potential disease mechanisms. However, identifying and prioritizing mechanisms for further analytical evaluation presents enormous challenges in terms of the quantity and diversity of published research. The application of data mining approaches to the literature offers the potential to identify and prioritize mechanisms for more focused and detailed analysis. Here we present MELODI, a literature mining platform that can identify mechanistic pathways between any two biomedical concepts. Two case studies demonstrate the potential uses of MELODI and how it can generate hypotheses for further investigation. First, an analysis of ETS-related gene ERG and prostate cancer derives the intermediate transcription factor SP1, recently confirmed to be physically interacting with ERG. Second, examining the relationship between a new potential risk factor for pancreatic cancer identifies possible mechanistic insights which can be studied in vitro. We have demonstrated the possible applications of MELODI, including two case studies. MELODI has been implemented as a Python/Django web application, and is freely available to use at [www.melodi.biocompute.org.uk]. © The Author(s) 2018. Published by Oxford University Press on behalf of the International Epidemiological Association

In vivo pH monitoring using boron doped diamond microelectrode and silver needles: Application to stomach disorder diagnosis

NASA Astrophysics Data System (ADS)

Fierro, Stéphane; Seishima, Ryo; Nagano, Osamu; Saya, Hideyuki; Einaga, Yasuaki

2013-11-01

This study presents the in vivo electrochemical monitoring of pH using boron doped diamond (BDD) microelectrode and silver needles for potential application in medical diagnosis. Accurate calibration curve for pH determination were obtained through in vitro electrochemical measurements. The increase induced in stomach pH by treatment with pantoprazole was used to demonstrate that it is possible to monitor the pH in vivo using the simple and noninvasive system proposed herein. Using the results of the in vivo and in vitro experiments, a quantitative analysis of the increase in stomach pH is also presented. It is proposed that the catheter-free pH monitoring system presented in this study could be potentially employed in any biological environment.

In vivo pH monitoring using boron doped diamond microelectrode and silver needles: application to stomach disorder diagnosis.

PubMed

Fierro, Stéphane; Seishima, Ryo; Nagano, Osamu; Saya, Hideyuki; Einaga, Yasuaki

2013-11-19

This study presents the in vivo electrochemical monitoring of pH using boron doped diamond (BDD) microelectrode and silver needles for potential application in medical diagnosis. Accurate calibration curve for pH determination were obtained through in vitro electrochemical measurements. The increase induced in stomach pH by treatment with pantoprazole was used to demonstrate that it is possible to monitor the pH in vivo using the simple and noninvasive system proposed herein. Using the results of the in vivo and in vitro experiments, a quantitative analysis of the increase in stomach pH is also presented. It is proposed that the catheter-free pH monitoring system presented in this study could be potentially employed in any biological environment.

An alternative approach to the Boltzmann distribution through the chemical potential

NASA Astrophysics Data System (ADS)

D'Anna, Michele; Job, Georg

2016-05-01

The Boltzmann distribution is one of the most significant results of classical physics. Despite its importance and its wide range of application, at high school level it is mostly presented without any derivation or link to some basic ideas. In this contribution we present an approach based on the chemical potential that allows to derive it directly from the basic idea of thermodynamical equilibrium.

An experimental study of potential residential and commercial applications of small-scale hybrid power systems

NASA Astrophysics Data System (ADS)

Acosta, Michael Anthony

The research presented in this thesis provides an understanding of small-scale hybrid power systems. Experiments were conducted to identify potential applications of renewable energy in residential and commercial applications in the Rio Grande Valley of Texas. Solar and wind energy converted into electric energy was stored in batteries and inverted to power common household and commercial appliances. Several small to medium size hybrid power systems were setup and utilized to conduct numerous tests to study renewable energy prospects and feasibility for various applications. The experimental results obtained indicate that carefully constructed solar power systems can provide people living in isolated communities with sufficient energy to consistently meet their basic power needs.

Multilevel Modeling and Policy Development: Guidelines and Applications to Medical Travel.

PubMed

Garcia-Garzon, Eduardo; Zhukovsky, Peter; Haller, Elisa; Plakolm, Sara; Fink, David; Petrova, Dafina; Mahalingam, Vaishali; Menezes, Igor G; Ruggeri, Kai

2016-01-01

Medical travel has expanded rapidly in recent years, resulting in new markets and increased access to medical care. Whereas several studies investigated the motives of individuals seeking healthcare abroad, the conventional analytical approach is limited by substantial caveats. Classical techniques as found in the literature cannot provide sufficient insight due to the nested nature of data generated. The application of adequate analytical techniques, specifically multilevel modeling, is scarce to non-existent in the context of medical travel. This study introduces the guidelines for application of multilevel techniques in public health research by presenting an application of multilevel modeling in analyzing the decision-making patterns of potential medical travelers. Benefits and potential limitations are discussed.

Silver metal nanoparticles study for biomedical and green house applications

NASA Astrophysics Data System (ADS)

Rauwel, E.; Simón-Gracia, L.; Guha, M.; Rauwel, P.; Kuunal, S.; Wragg, D.

2017-02-01

Metallic nanoparticles (MNP) with diameters ranging from 2 to 100nm have received extensive attention during the past decades due to their many potential applications. This paper presents a structural and cytotoxicity study of silver metal nanoparticles targeted towards biomedical applications. Spherical Ag MNPs of diameter from 20 to 50 nm have been synthesized. The encapsulation of Ag MNPs inside pH-sensitive polymersomes has been also studied for the development of biomedical applications. A cytotoxicity study of the Ag MNPs against primary prostatic cancer cell line (PPC-1) has demonstrated a high mortality rate for concentrations ranging from 100 to 200mg/L. The paper will discuss the potential for therapeutic treatments of these Ag MNPs.

Multilevel Modeling and Policy Development: Guidelines and Applications to Medical Travel

PubMed Central

Garcia-Garzon, Eduardo; Zhukovsky, Peter; Haller, Elisa; Plakolm, Sara; Fink, David; Petrova, Dafina; Mahalingam, Vaishali; Menezes, Igor G.; Ruggeri, Kai

2016-01-01

Medical travel has expanded rapidly in recent years, resulting in new markets and increased access to medical care. Whereas several studies investigated the motives of individuals seeking healthcare abroad, the conventional analytical approach is limited by substantial caveats. Classical techniques as found in the literature cannot provide sufficient insight due to the nested nature of data generated. The application of adequate analytical techniques, specifically multilevel modeling, is scarce to non-existent in the context of medical travel. This study introduces the guidelines for application of multilevel techniques in public health research by presenting an application of multilevel modeling in analyzing the decision-making patterns of potential medical travelers. Benefits and potential limitations are discussed. PMID:27252672

Industrial applications of metal-organic frameworks.

PubMed

Czaja, Alexander U; Trukhan, Natalia; Müller, Ulrich

2009-05-01

New materials are prerequisite for major breakthrough applications influencing our daily life, and therefore are pivotal for the chemical industry. Metal-organic frameworks (MOFs) constitute an emerging class of materials useful in gas storage, gas purification and separation applications as well as heterogeneous catalysis. They not only offer higher surface areas and the potential for enhanced activity than currently used materials like base metal oxides, but also provide shape/size selectivity which is important both for separations and catalysis. In this critical review an overview of the potential applications of MOFs in the chemical industry is presented. Furthermore, the synthesis and characterization of the materials are briefly discussed from the industrial perspective (88 references).

Recent Progress of Microfluidics in Translational Applications

PubMed Central

Liu, Zongbin; Han, Xin

2016-01-01

Microfluidics, featuring microfabricated structures, is a technology for manipulating fluids at the micrometer scale. The small dimension and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design is presented. The potential future developments in the translational microfluidics field are also discussed. PMID:27091777

Medical applications of ultra-short pulse lasers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kim, B M; Marion, J E

1999-06-08

The medical applications for ultra short pulse lasers (USPLs) and their associated commercial potential are reviewed. Short pulse lasers offer the surgeon the possibility of precision cutting or disruption of tissue with virtually no thermal or mechanical damage to the surrounding areas. Therefore the USPL offers potential improvement to numerous existing medical procedures. Secondly, when USPLs are combined with advanced tissue diagnostics, there are possibilities for tissue-selective precision ablation that may allow for new surgeries that cannot at present be performed. Here we briefly review the advantages of short pulse lasers, examine the potential markets both from an investment communitymore » perspective, and from the view. of the technology provider. Finally nominal performance and cost requirements for the lasers, delivery systems and diagnostics and the present state of development will be addressed.« less

Applications of aerospace technology in biology and medicine

NASA Technical Reports Server (NTRS)

1973-01-01

The results are reported of the medically related activities of the NASA Application Team Program at the Research Triangle Institute. Fourteen medical organizations are presently participating in the RTI Application Team Program: The accomplishments of the Research Triangle Institute Application Team during the reporting period were as follows: The team identified 21 new problems for investigation, accomplished 4 technology applications and 3 potential technology applications, closed 21 old problems, and on February 28, 1973, had a total of 57 problems under active investigation.

Frontiers in propulsion research: Laser, matter-antimatter, excited helium, energy exchange thermonuclear fusion

NASA Technical Reports Server (NTRS)

Papailiou, D. D. (Editor)

1975-01-01

Concepts are described that presently appear to have the potential for propulsion applications in the post-1990 era of space technology. The studies are still in progress, and only the current status of investigation is presented. The topics for possible propulsion application are lasers, nuclear fusion, matter-antimatter annihilation, electronically excited helium, energy exchange through the interaction of various fields, laser propagation, and thermonuclear fusion technology.

Presentations: Adverse Outcome Pathways for Abnormal Phenotypes

EPA Science Inventory

Birth defects affect many infants and the etiology for most are unknown. Although environmental factors are known to influence pregnancy outcome, thousands of chemicals, present in the environment, are untested for developmental toxicity potential. Application of computational p...

Micro-Coplanar Striplines: New Transmission Media for Microwave Applications

NASA Technical Reports Server (NTRS)

Goverdhanam, Kavita; Simons, Rainee N.; Katehi, Linda P. B.

1998-01-01

In this paper a new transmission line for microwave applications, referred to here as the Micro-Coplanar Stripline (MCPS), is introduced. The propagation characteristics, such as, characteristic impedance (Z(sub 0) and effective dielectric constant (epsilon eff) for a range of MCPS geometries have been modeled using the Finite Difference Time Domain (FDTD) Technique and presented here. Also, preliminary experimental results on the performance of an MCP-Microstrip transition and an MCPS-fed patch antenna are presented. The results indicate several potential applications of the MCPS line in microwave integrated circuit technology.

Stochastic Formalism for Thermally Driven Distribution Frontier: A Nonempirical Approach to the Potential Escape Problem

NASA Astrophysics Data System (ADS)

Akashi, Ryosuke; Nagornov, Yuri S.

2018-06-01

We develop a non-empirical scheme to search for the minimum-energy escape paths from the minima of the potential surface to unknown saddle points nearby. A stochastic algorithm is constructed to move the walkers up the surface through the potential valleys. This method employs only the local gradient and diagonal part of the Hessian matrix of the potential. An application to a two-dimensional model potential is presented to demonstrate the successful finding of the paths to the saddle points. The present scheme could serve as a starting point toward first-principles simulation of rare events across the potential basins free from empirical collective variables.

Applications of aerospace technology in biology and medicine

NASA Technical Reports Server (NTRS)

Wooten, F. T.

1972-01-01

The results are presented of the medically related activities of the NASA Application Team Program at the Research Triangle Institute. The accomplishments of the Research Triangle Institute Application Team during the reporting period are as follows: The team has identified 44 new problems for investigation, has accomplished 8 technology applications and 8 potential technology applications, has closed 88 old problems, and reactivated 3 old problems, and on August 31, 1972, has a total of 57 problems under active investigation.

Three-dimensional solutions of the magnetohydrostatic equations for rigidly rotating magnetospheres in cylindrical coordinates

NASA Astrophysics Data System (ADS)

Wilson, F.; Neukirch, T.

2018-01-01

We present new analytical three-dimensional solutions of the magnetohydrostatic equations, which are applicable to the co-rotating frame of reference outside a rigidly rotating cylindrical body, and have potential applications to planetary magnetospheres and stellar coronae. We consider the case with centrifugal force only, and use a transformation method in which the governing equation for the "pseudo-potential" (from which the magnetic field can be calculated) becomes the Laplace partial differential equation. The new solutions extend the set of previously found solutions to those of a "fractional multipole" nature, and offer wider possibilities for modelling than before. We consider some special cases, and present example solutions.

Conference on Charge-Coupled Device Technology and Applications

NASA Technical Reports Server (NTRS)

1976-01-01

Papers were presented from the conference on charge coupled device technology and applications. The following topics were investigated: data processing; infrared; devices and testing; electron-in, x-ray, radiation; and applications. The emphasis was on the advances of mutual relevance and potential significance both to industry and NASA's current and future requirements in all fields of imaging, signal processing and memory.

EEG Recording and Online Signal Processing on Android: A Multiapp Framework for Brain-Computer Interfaces on Smartphone

PubMed Central

Debener, Stefan; Emkes, Reiner; Volkening, Nils; Fudickar, Sebastian; Bleichner, Martin G.

2017-01-01

Objective Our aim was the development and validation of a modular signal processing and classification application enabling online electroencephalography (EEG) signal processing on off-the-shelf mobile Android devices. The software application SCALA (Signal ProCessing and CLassification on Android) supports a standardized communication interface to exchange information with external software and hardware. Approach In order to implement a closed-loop brain-computer interface (BCI) on the smartphone, we used a multiapp framework, which integrates applications for stimulus presentation, data acquisition, data processing, classification, and delivery of feedback to the user. Main Results We have implemented the open source signal processing application SCALA. We present timing test results supporting sufficient temporal precision of audio events. We also validate SCALA with a well-established auditory selective attention paradigm and report above chance level classification results for all participants. Regarding the 24-channel EEG signal quality, evaluation results confirm typical sound onset auditory evoked potentials as well as cognitive event-related potentials that differentiate between correct and incorrect task performance feedback. Significance We present a fully smartphone-operated, modular closed-loop BCI system that can be combined with different EEG amplifiers and can easily implement other paradigms. PMID:29349070

EEG Recording and Online Signal Processing on Android: A Multiapp Framework for Brain-Computer Interfaces on Smartphone.

PubMed

Blum, Sarah; Debener, Stefan; Emkes, Reiner; Volkening, Nils; Fudickar, Sebastian; Bleichner, Martin G

2017-01-01

Our aim was the development and validation of a modular signal processing and classification application enabling online electroencephalography (EEG) signal processing on off-the-shelf mobile Android devices. The software application SCALA (Signal ProCessing and CLassification on Android) supports a standardized communication interface to exchange information with external software and hardware. In order to implement a closed-loop brain-computer interface (BCI) on the smartphone, we used a multiapp framework, which integrates applications for stimulus presentation, data acquisition, data processing, classification, and delivery of feedback to the user. We have implemented the open source signal processing application SCALA. We present timing test results supporting sufficient temporal precision of audio events. We also validate SCALA with a well-established auditory selective attention paradigm and report above chance level classification results for all participants. Regarding the 24-channel EEG signal quality, evaluation results confirm typical sound onset auditory evoked potentials as well as cognitive event-related potentials that differentiate between correct and incorrect task performance feedback. We present a fully smartphone-operated, modular closed-loop BCI system that can be combined with different EEG amplifiers and can easily implement other paradigms.

Active Brownian motion models and applications to ratchets

NASA Astrophysics Data System (ADS)

Fiasconaro, A.; Ebeling, W.; Gudowska-Nowak, E.

2008-10-01

We give an overview over recent studies on the model of Active Brownian Motion (ABM) coupled to reservoirs providing free energy which may be converted into kinetic energy of motion. First, we present an introduction to a general concept of active Brownian particles which are capable to take up energy from the source and transform part of it in order to perform various activities. In the second part of our presentation we consider applications of ABM to ratchet systems with different forms of differentiable potentials. Both analytical and numerical evaluations are discussed for three cases of sinusoidal, staircaselike and Mateos ratchet potentials, also with the additional loads modelled by tilted potential structure. In addition, stochastic character of the kinetics is investigated by considering perturbation by Gaussian white noise which is shown to be responsible for driving the directionality of the asymptotic flux in the ratchet. This stochastically driven directionality effect is visualized as a strong nonmonotonic dependence of the statistics of the right versus left trajectories of motion leading to a net current of particles. Possible applications of the ratchet systems to molecular motors are also briefly discussed.

Mobile applications in children with cerebral palsy.

PubMed

Rodríguez Mariblanca, M; Cano de la Cuerda, R

2017-12-21

Cerebral palsy (CP) is one of the most common developmental disorders. Technological development has enabled a transformation of the healthcare sector, which can offer more individualised, participatory, and preventive services. Within this context of new technology applied to the healthcare sector, mobile applications, or apps, constitute a very promising tool for the management of children with CP. The purpose of this article is to perform a systematic review of the information published about various mobile applications either directly related to CP or with potential to be useful in the context of the disease, and to describe, analyse, and classify these applications. A literature search was carried out to gather articles published in English or Spanish between 2011 and 2017 which presented, analysed, or validated applications either specifically designed or potentially useful for CP. Furthermore, a search for mobile applications was conducted in the main mobile application markets. A total of 63 applications were found in biomedical databases and mobile application markets, of which 40 were potentially useful for CP and 23 were specifically designed for the condition (11 for information, 3 for evaluation, and 9 for treatment). There are numerous mobile applications either specifically designed for or with potential to be useful in the field of CP. However, despite the existing scientific evidence, the low methodological quality of scientific articles makes it impossible to generalise the use of these tools. Copyright © 2017 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.

A Selected Bibliography of On-Line Visual Displays and Their Applications.

ERIC Educational Resources Information Center

Braidwood, J.

Contained in this bibliography are 312 references as they related to general principles and problems of information display, man-computer interaction, present and possible future display equipment, ergonomic aspects of display design, and current and potential applications, especially to information processing. (Author/MM)

DEVELOPMENT OF CFD SIMULATION APPLICATIONS FOR LOCAL-SCALE AREAS AND POTENTIAL INTERFACE WITH MESOSCALE MODELS

EPA Science Inventory

The presentation summarizes developments of ongoing applications of fine-scale (geometry specific) CFD simulations to urban areas within atmospheric boundary layers. Enabling technology today and challenges for the future are discussed. There is a challenging need to develop a ...

How Ordinary Meaning Underpins the Meaning of Mathematics.

ERIC Educational Resources Information Center

Ormell, Christopher

1991-01-01

Discusses the meaning of mathematics by looking at its uses in the real world. Offers mathematical modeling as a way to represent mathematical applications in real or potential situations. Presents levels of applicability, modus operandi, relationship to "pure mathematics," and consequences for education for mathematical modeling. (MDH)

Impact of cool storage air-conditioning in commercial sector on power system operation in Thailand

DOE Office of Scientific and Technical Information (OSTI.GOV)

Surapong, C.; Bundit, L.

The results are presented from an investigation into the potential application for cool storage air-conditioning, and the resultant beneficial impact on power system operation in Thailand is discussed. Field assessment through interviews with decision makers in the identified customer groups produces results that show good potential for cool storage application. Results from a computer program used to calculate power production cost and other characteristics show that substantial benefits would also accrue to the generating utility.

Recent Progress of Microfluidics in Translational Applications.

PubMed

Liu, Zongbin; Han, Xin; Qin, Lidong

2016-04-20

Microfluidics, featuring microfabricated structures, is a technology for manipulating fluids at the micrometer scale. The small dimension and flexibility of microfluidic systems are ideal for mimicking molecular and cellular microenvironment, and show great potential in translational research and development. Here, the recent progress of microfluidics in biological and biomedical applications, including molecular analysis, cellular analysis, and chip-based material delivery and biomimetic design is presented. The potential future developments in the translational microfluidics field are also discussed. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Compact Polarimetry Potentials

NASA Technical Reports Server (NTRS)

Truong-Loi, My-Linh; Dubois-Fernandez, Pascale; Pottier, Eric

2011-01-01

The goal of this study is to show the potential of a compact-pol SAR system for vegetation applications. Compact-pol concept has been suggested to minimize the system design while maximize the information and is declined as the ?/4, ?/2 and hybrid modes. In this paper, the applications such as biomass and vegetation height estimates are first presented, then, the equivalence between compact-pol data simulated from full-pol data and compact-pol data processed from raw data as such is shown. Finally, a calibration procedure using external targets is proposed.

Remote detection of explosives using Raman spectroscopy

NASA Astrophysics Data System (ADS)

Fulton, Jack

2011-05-01

Stand-off detection of potentially hazardous small molecules at distances that allow the user to be safe has many applications, including explosives and chemical threats. The Naval Surface Warfare Center, Crane Division, with EYZtek, Inc. of Ohio, developed a prototype stand-off, eye-safe Raman spectrometer. With a stand-off distance greater than twenty meters and scanning optics, this system has the potential of addressing particularly difficult challenges in small molecule detection. An overview of the system design and desired application space is presented.

Revealing the optoelectronic and thermoelectric properties of the Zintl quaternary arsenides ACdGeAs{sub 2} (A = K, Rb)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Azam, Sikander; Khan, Saleem Ayaz; Goumri-Said, Souraya, E-mail: Souraya.Goumri-Said@chemistry.gatech.edu

Highlights: • Zintl tetragonal phase ACdGeAs{sub 2} (A = K, Rb) are chalcopyrite and semiconductors. • Their direct band gap is suitable for PV, optolectronic and thermoelectric applications. • Combination of DFT and Boltzmann transport theory is employed. • The present arsenides are found to be covalent materials. - Abstract: Chalcopyrite semiconductors have attracted much attention due to their potential implications in photovoltaic and thermoelectric applications. First principle calculations were performed to investigate the electronic, optical and thermoelectric properties of the Zintl tetragonal phase ACdGeAs{sub 2} (A = K, Rb) using the full potential linear augmented plane wave method andmore » the Engle–Vosko GGA (EV–GGA) approximation. The present compounds are found semiconductors with direct band gap and covalent bonding character. The optical transitions are investigated via the dielectric function (real and imaginary parts) along with other related optical constants including refractive index, reflectivity and energy-loss spectrum. Combining results from DFT and Boltzmann transport theory, we reported the thermoelectric properties such as the Seebeck’s coefficient, electrical and thermal conductivity, figure of merit and power factor as function of temperatures. The present chalcopyrite Zintl quaternary arsenides deserve to be explored for their potential applications as thermoelectric materials and for photovoltaic devices.« less

Catalytically-active inclusion bodies-Carrier-free protein immobilizates for application in biotechnology and biomedicine.

PubMed

Krauss, Ulrich; Jäger, Vera D; Diener, Martin; Pohl, Martina; Jaeger, Karl-Erich

2017-09-20

Bacterial inclusion bodies (IBs) consist of unfolded protein aggregates and represent inactive waste products often accumulating during heterologous overexpression of recombinant genes in Escherichia coli. This general misconception has been challenged in recent years by the discovery that IBs, apart from misfolded polypeptides, can also contain substantial amounts of active and thus correctly or native-like folded protein. The corresponding catalytically-active inclusion bodies (CatIBs) can be regarded as a biologically-active sub-micrometer sized biomaterial or naturally-produced carrier-free protein immobilizate. Fusion of polypeptide (protein) tags can induce CatIB formation paving the way towards the wider application of CatIBs in synthetic chemistry, biocatalysis and biomedicine. In the present review we summarize the history of CatIBs, present the molecular-biological tools that are available to induce CatIB formation, and highlight potential lines of application. In the second part findings regarding the formation, architecture, and structure of (Cat)IBs are summarized. Finally, an overview is presented about the available bioinformatic tools that potentially allow for the prediction of aggregation and thus (Cat)IB formation. This review aims at demonstrating the potential of CatIBs for biotechnology and hopefully contributes to a wider acceptance of this promising, yet not widely utilized, protein preparation. Copyright © 2017 Elsevier B.V. All rights reserved.

Human health risk assessment of nitrosamines and nitramines for potential application in CO2 capture.

PubMed

Ravnum, S; Rundén-Pran, E; Fjellsbø, L M; Dusinska, M

2014-07-01

Emission and accumulation of carbon dioxide (CO2) in the atmosphere exert an environmental and climate change challenge. An attempt to deal with this challenge is made at Mongstad by application of amines for CO2 capture and storage (CO2 capture Mongstad (CCM) project). As part of the CO2 capture process, nitrosamines and nitramines may be emitted. Toxicological testing of nitrosamines and nitramines indicate a genotoxic potential of these substances. Here we present a risk characterization and assessment for five nitrosamines (N-Nitrosodi-methylamine (NDMA) N-Nitrosodi-ethylamine (NDEA), N-Nitroso-morpholine (NNM), N-Nitroso-piperidine (NPIP), and Dinitroso-piperazine (DNP)) and two nitramines (N-Methyl-nitramine (NTMA), Dimethyl-nitramine (NDTMA)), which are potentially emitted from the CO2 capture plant (CCP). Human health risk assessment of genotoxic non-threshold substances is a heavily debated topic, and no consensus methodology exists internationally. Extrapolation modeling from high-dose animal exposures to low-dose human exposures can be crucial for the final risk calculation. In the work presented here, different extrapolation models are discussed, and suggestions on applications are given. Then, preferred methods for calculating derived minimal effect level (DMEL) are presented with the selected nitrosamines and nitramines. Copyright © 2014 Elsevier Inc. All rights reserved.

PPP effectiveness study. [automatic procedures recording and crew performance monitoring system

NASA Technical Reports Server (NTRS)

Arbet, J. D.; Benbow, R. L.

1976-01-01

This design note presents a study of the Procedures and Performance Program (PPP) effectiveness. The intent of the study is to determine manpower time savings and the improvements in job performance gained through PPP automated techniques. The discussion presents a synopsis of PPP capabilities and identifies potential users and associated applications, PPP effectiveness, and PPP applications to other simulation/training facilities. Appendix A provides a detailed description of each PPP capability.

Transparent wood for functional and structural applications

NASA Astrophysics Data System (ADS)

Li, Yuanyuan; Fu, Qiliang; Yang, Xuan; Berglund, Lars

2017-12-01

Optically transparent wood combines mechanical performance with optical functionalities is an emerging candidate for applications in smart buildings and structural optics and photonics. The present review summarizes transparent wood preparation methods, optical and mechanical performance, and functionalization routes, and discusses potential applications. The various challenges are discussed for the purpose of improved performance, scaled-up production and realization of advanced applications. This article is part of a discussion meeting issue `New horizons for cellulose nanotechnology'.

Investigation on application of genetic algorithms to optimal reactive power dispatch of power systems

NASA Astrophysics Data System (ADS)

Wu, Q. H.; Ma, J. T.

1993-09-01

A primary investigation into application of genetic algorithms in optimal reactive power dispatch and voltage control is presented. The application was achieved, based on (the United Kingdom) National Grid 48 bus network model, using a novel genetic search approach. Simulation results, compared with that obtained using nonlinear programming methods, are included to show the potential of applications of the genetic search methodology in power system economical and secure operations.

Review on thin-film transistor technology, its applications, and possible new applications to biological cells

NASA Astrophysics Data System (ADS)

Tixier-Mita, Agnès; Ihida, Satoshi; Ségard, Bertrand-David; Cathcart, Grant A.; Takahashi, Takuya; Fujita, Hiroyuki; Toshiyoshi, Hiroshi

2016-04-01

This paper presents a review on state-of-the-art of thin-film transistor (TFT) technology and its wide range of applications, not only in liquid crystal displays (TFT-LCDs), but also in sensing devices. The history of the evolution of the technology is first given. Then the standard applications of TFT-LCDs, and X-ray detectors, followed by state-of-the-art applications in the field of chemical and biochemical sensing are presented. TFT technology allows the fabrication of dense arrays of independent and transparent microelectrodes on large glass substrates. The potential of these devices as electrical substrates for biological cell applications is then described. The possibility of using TFT array substrates as new tools for electrical experiments on biological cells has been investigated for the first time by our group. Dielectrophoresis experiments and impedance measurements on yeast cells are presented here. Their promising results open the door towards new applications of TFT technology.

Lunar rated fasteners

NASA Technical Reports Server (NTRS)

Gupton, Lindsey; Hyde, Steve; Mckillip, Dan; Player, Bryan; Smith, Greg

1988-01-01

A catalog of fasteners is presented for a variety of applications to be used in a lunar environment. The fastening applications targeted include: covers, panels, hatches, bearings, wheels, gears, pulleys, anchors for the lunar surface and structural fasteners (general duty preloadable). The robotic installation and removal of each fastener is presented along with a discussion of failure modes. Structural performance data is tabulated for various configurations. Potential materials for the space environment are presented along with recommendations of appropriate solid film lubricants. Three original fastener designs were found suitable for the lunar environment. A structural analysis is presented for each original design.

Applications of QCL mid-IR imaging to the advancement of pathology

NASA Astrophysics Data System (ADS)

Sreedhar, Hari; Varma, Vishal K.; Bird, Benjamin; Guzman, Grace; Walsh, Michael J.

2017-03-01

Quantum Cascade Laser (QCL) spectroscopic imaging is a novel technique with many potential applications to histopathology. Like traditional Fourier Transform Infrared (FT-IR) imaging, QCL spectroscopic imaging derives biochemical data coupled to the spatial information of a tissue sample, and can be used to improve the diagnostic and prognostic value of assessment of a tissue biopsy. This technique also offers advantages over traditional FT-IR imaging, specifically the capacity for discrete frequency and real-time imaging. In this work we present applications of QCL spectroscopic imaging to tissue samples, including discrete frequency imaging, to compare with FT-IR and its potential value to pathology.

Steady and Oscillatory, Subsonic and Supersonic, Aerodynamic Pressure and Generalized Forces for Complex Aircraft Configurations and Applications to Flutter. M.S. Thesis

NASA Technical Reports Server (NTRS)

Chen, L. T.

1975-01-01

A general method for analyzing aerodynamic flows around complex configurations is presented. By applying the Green function method, a linear integral equation relating the unknown, small perturbation potential on the surface of the body, to the known downwash is obtained. The surfaces of the aircraft, wake and diaphragm (if necessary) are divided into small quadrilateral elements which are approximated with hyperboloidal surfaces. The potential and its normal derivative are assumed to be constant within each element. This yields a set of linear algebraic equations and the coefficients are evaluated analytically. By using Gaussian elimination method, equations are solved for the potentials at the centroids of elements. The pressure coefficient is evaluated by the finite different method; the lift and moment coefficients are evaluated by numerical integration. Numerical results are presented, and applications to flutter are also included.

An integrated power/attitude control system /IPACS/ for space vehicle application

NASA Technical Reports Server (NTRS)

Anderson, W. W.; Keckler, C. R.

1973-01-01

An integrated power and attitude control system (IPACS) concept with potential application to a broad class of space missions is discussed. The concept involves the storage and supply on demand of electrical energy in rotating flywheels while simultaneously providing control torques by controlled precession of the flywheels. The system is thus an alternative to the storage batteries used on present spacecraft while providing similar capability for attitude control as that represented by a control moment gyroscope (CMG) system. Potential IPACS configurations discussed include single- and double-rotor double-gimbal IPACS units. Typical sets of control laws which would manage the momentum and energy exchange between the IPACS and a typical space vehicle are discussed. Discussion of a simulation of a typical potential IPACS configuration and candidate mission concerned with pointing capability, power supply and demand flow, and discussion of the interactions between stabilization and control requirements and power flow requirements are presented.

Potential impact of high temperature superconductors on MAGLEV transportation

NASA Astrophysics Data System (ADS)

Hull, J. R.

1992-02-01

This report describes the potential impact that high-temperature superconductors (HTS's) may have on transportation by magnetically levitated vehicles. It is not intended as a planning document, but rather as an overview of potential HTS applications to magnetic-levitation (maglev) transportation. The present maglev program in the United States is summarized, and the present status of development of HTS's is described. Areas identified for possible impact on maglev technology are: (1) liquid-nitrogen-cooled levitation magnets; (2) magnetic-field shielding of the passenger compartment; (3) superconducting magnetic energy storage for wayside power; (4) superconducting bearings for flywheel energy storage for wayside power; (5) downleads to continuously powered liquid-helium-cooled levitation magnets; and (6) liquid-hydrogen-cooled levitation magnets and linear motor propulsion windings. Major technical issues that remain to be resolved for the use of HTS's in maglev applications include thermal magnetic stability, mechanical properties, and critical current density at liquid-nitrogen temperatures.

Development of Risk Assessment Methodology for Land Application and Distribution and Marketing of Municipal Sludge

EPA Science Inventory

This is one of a series of reports that present methodologies for assessing the potential risks to humans or other organisms from the disposal or reuse of municipal sludge. The sludge management practices addressed by this series include land application practices, distribution a...

Evidence That International Undergraduates Can Succeed Academically Despite Struggling with English

ERIC Educational Resources Information Center

Fass-Holmes, Barry; Vaughn, Allison A.

2015-01-01

Many American universities require international applicants whose native language is not English to submit English proficiency exam scores presumably because of proficiency's potential to predict future academic success. The present study provides evidence, however, that such applicants can succeed academically despite struggling with English.…

U.S. EPA National Stormwater Calculator Mobile Web Application

EPA Science Inventory

This presentation gives a brief overview of the new mobile web application version of EPA's National Stormwater Calculator. It is meant to give an overview of the development of the mobile web app and to demonstrate potential uses of the new version of the National Stormwater Cal...

BASINS and WEPP Climate Assessment Tools (CAT): Case Study Guide to Potential Applications (External Review Draft)

EPA Science Inventory

This draft report supports application of two recently developed water modeling tools, the BASINS and WEPP climate assessment tools. The report presents a series of short case studies designed to illustrate the capabilities of these tools for conducting scenario based assessments...

24 CFR 886.101 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-04-01

... potentially serious financial problems which, on the basis of financial and/or management analysis, appear to... potentially serious financial difficulties. A first priority should be given to projects with presently serious financial problems, which are likely to result in a claim on the insurance fund in the near future...

24 CFR 886.101 - Applicability.

Code of Federal Regulations, 2011 CFR

2011-04-01

... potentially serious financial problems which, on the basis of financial and/or management analysis, appear to... potentially serious financial difficulties. A first priority should be given to projects with presently serious financial problems, which are likely to result in a claim on the insurance fund in the near future...

Alternative therapy applications for postoperative nausea and vomiting.

PubMed

Chiravalle, Paulette; McCaffrey, Ruth

2005-01-01

The potential for postoperative nausea and vomiting is present in any patient who undergoes surgery and both are unpleasant and potentially dangerous consequences of surgery. Three types of complementary and alternative therapies that may help patients with postoperative nausea and vomiting include acupressure, acupuncture, and aromatherapy.

Injectable Hydrogels for Cardiac Tissue Repair after Myocardial Infarction

PubMed Central

Khattab, Ahmad; Islam, Mohammad Ariful; Hweij, Khaled Abou; Zeitouny, Joya; Waters, Renae; Sayegh, Malek; Hossain, Md Monowar; Paul, Arghya

2015-01-01

Cardiac tissue damage due to myocardial infarction (MI) is one of the leading causes of mortality worldwide. The available treatments of MI include pharmaceutical therapy, medical device implants, and organ transplants, all of which have severe limitations including high invasiveness, scarcity of donor organs, thrombosis or stenosis of devices, immune rejection, and prolonged hospitalization time. Injectable hydrogels have emerged as a promising solution for in situ cardiac tissue repair in infarcted hearts after MI. In this review, an overview of various natural and synthetic hydrogels for potential application as injectable hydrogels in cardiac tissue repair and regeneration is presented. The review starts with brief discussions about the pathology of MI, its current clinical treatments and their limitations, and the emergence of injectable hydrogels as a potential solution for post MI cardiac regeneration. It then summarizes various hydrogels, their compositions, structures and properties for potential application in post MI cardiac repair, and recent advancements in the application of injectable hydrogels in treatment of MI. Finally, the current challenges associated with the clinical application of injectable hydrogels to MI and their potential solutions are discussed to help guide the future research on injectable hydrogels for translational therapeutic applications in regeneration of cardiac tissue after MI. PMID:27668147

Military applications of reusable launch vehicles (RLVs)

NASA Astrophysics Data System (ADS)

Sponable, Jess M.

1996-03-01

With the development and operational fielding of fully reusable launch vehicles (RLVs) becoming imminent, coupled with the ``end of the Cold War'' and fractionalization of the former ``bi-polar'' world into a ``multi-polar'' one, the need and potential for military versions of RLVs are being recognized by the military strategic planner. Recognizing the instability of the world order, especially with the potential for terrorism from all quarters, planning for the development of systems capable of defending our critical space based assests is becoming more essential. This paper presents some of the potential military applications of RLVs to support the Nation's defense and security interests world-wide.

Molecular-based design and emerging applications of nanoporous carbon spheres

NASA Astrophysics Data System (ADS)

Liu, Jian; Wickramaratne, Nilantha P.; Qiao, Shi Zhang; Jaroniec, Mietek

2015-08-01

Over the past decade, considerable progress has been made in the synthesis and applications of nanoporous carbon spheres ranging in size from nanometres to micrometres. This Review presents the primary techniques for preparing nanoporous carbon spheres and the seminal research that has inspired their development, presented potential applications and uncovered future challenges. First we provide an overview of the synthesis techniques, including the Stöber method and those based on templating, self-assembly, emulsion and hydrothermal carbonization, with special emphasis on the design and functionalization of nanoporous carbon spheres at the molecular level. Next, we cover the key applications of these spheres, including adsorption, catalysis, separation, energy storage and biomedicine -- all of which might benefit from the regular geometry, good liquidity, tunable porosity and controllable particle-size distribution offered by nanoporous carbon spheres. Finally, we present the current challenges and opportunities in the development and commercial applications of nanoporous carbon spheres.

Molecular-based design and emerging applications of nanoporous carbon spheres.

PubMed

Liu, Jian; Wickramaratne, Nilantha P; Qiao, Shi Zhang; Jaroniec, Mietek

2015-08-01

Over the past decade, considerable progress has been made in the synthesis and applications of nanoporous carbon spheres ranging in size from nanometres to micrometres. This Review presents the primary techniques for preparing nanoporous carbon spheres and the seminal research that has inspired their development, presented potential applications and uncovered future challenges. First we provide an overview of the synthesis techniques, including the Stöber method and those based on templating, self-assembly, emulsion and hydrothermal carbonization, with special emphasis on the design and functionalization of nanoporous carbon spheres at the molecular level. Next, we cover the key applications of these spheres, including adsorption, catalysis, separation, energy storage and biomedicine — all of which might benefit from the regular geometry, good liquidity, tunable porosity and controllable particle-size distribution offered by nanoporous carbon spheres. Finally, we present the current challenges and opportunities in the development and commercial applications of nanoporous carbon spheres.

A Review on Graphene-Based Nanomaterials in Biomedical Applications and Risks in Environment and Health

NASA Astrophysics Data System (ADS)

Dasari Shareena, Thabitha P.; McShan, Danielle; Dasmahapatra, Asok K.; Tchounwou, Paul B.

2018-07-01

Graphene-based nanomaterials (GBNs) have attracted increasing interests of the scientific community due to their unique physicochemical properties and their applications in biotechnology, biomedicine, bioengineering, disease diagnosis and therapy. Although a large amount of researches have been conducted on these novel nanomaterials, limited comprehensive reviews are published on their biomedical applications and potential environmental and human health effects. The present research aimed at addressing this knowledge gap by examining and discussing: (1) the history, synthesis, structural properties and recent developments of GBNs for biomedical applications; (2) GBNs uses as therapeutics, drug/gene delivery and antibacterial materials; (3) GBNs applications in tissue engineering and in research as biosensors and bioimaging materials; and (4) GBNs potential environmental effects and human health risks. It also discussed the perspectives and challenges associated with the biomedical applications of GBNs.[Figure not available: see fulltext.

A better understanding of organic electrochemical transistors for biosensing applications (Presentation Recording)

NASA Astrophysics Data System (ADS)

Friedlein, Jacob T.; Malliaras, George G.; Shaheen, Sean E.; McLeod, Robert R.

2015-10-01

Due to their biocompatibility, high transconductance, and low operating voltages, organic electrochemical transistors (OECTs) are promising platforms for biosensing applications. They have been used for measuring enzymes such as glucose and lactate, detecting disruptions of epithelial cell integrity, and amplifying epileptic voltage signals in rat brains. Accelerating the development of OECTs in this diverse range of potential applications, and those unforeseen, requires continued investigation of the device physics and material properties. In this presentation, we will describe our work to better understand OECT behavior, and we will discuss how this understanding can be used to develop more effective biosensors.

Cherenkov and Scintillation Properties of Cubic Zirconium

NASA Technical Reports Server (NTRS)

Christl, M.J.; Adams, J.H.; Parnell, T.A.; Kuznetsov, E.N.

2008-01-01

Cubic zirconium (CZ) is a high index of refraction (n =2.17) material that we have investigated for Cherenkov counter applications. Laboratory and proton accelerator tests of an 18cc sample of CZ show that the expected fast Cherenkov response is accompanied by a longer scintillation component that can be separated by pulse shaping. This presents the possibility of novel particle spectrometers which exploits both properties of CZ. Other high index materials being examined for Cherenkov applications will be discussed. Results from laboratory tests and an accelerator exposure will be presented and a potential application in solar energetic particle instruments will be discussed

REVIEWS OF TOPICAL PROBLEMS: Application of cybernetic methods in physics

NASA Astrophysics Data System (ADS)

Fradkov, Aleksandr L.

2005-02-01

Basic aspects of the subject and methodology for a new and rapidly developing area of research that has emerged at the intersection of physics and control theory (cybernetics) and emphasizes the application of cybernetic methods to the study of physical systems are reviewed. Speed-gradient and Hamiltonian solutions for energy control problems in conservative and dissipative systems are presented. Application examples such as the Kapitza pendulum, controlled overcoming of a potential barrier, and controlling coupled oscillators and molecular systems are presented. A speed-gradient approach to modeling the dynamics of physical systems is discussed.

Digital signal processing of the phonocardiogram: review of the most recent advancements.

PubMed

Durand, L G; Pibarot, P

1995-01-01

The objective of the present paper is to provide a detailed review of the most recent developments in instrumentation and signal processing of digital phonocardiography and heart auscultation. After a short introduction, the paper presents a brief history of heart auscultation and phonocardiography, which is followed by a summary of the basic theories and controversies regarding the genesis of the heart sounds. The application of spectral analysis and the potential of new time-frequency representations and cardiac acoustic mapping to resolve the controversies and better understand the genesis and transmission of heart sounds and murmurs within the heart-thorax acoustic system are reviewed. The most recent developments in the application of linear predictive coding, spectral analysis, time-frequency representation techniques, and pattern recognition for the detection and follow-up of native and prosthetic valve degeneration and dysfunction are also presented in detail. New areas of research and clinical applications and areas of potential future developments are then highlighted. The final section is a discussion about a multidegree of freedom theory on the origin of the heart sounds and murmurs, which is completed by the authors' conclusion.

Towards Evolving Electronic Circuits for Autonomous Space Applications

NASA Technical Reports Server (NTRS)

Lohn, Jason D.; Haith, Gary L.; Colombano, Silvano P.; Stassinopoulos, Dimitris

2000-01-01

The relatively new field of Evolvable Hardware studies how simulated evolution can reconfigure, adapt, and design hardware structures in an automated manner. Space applications, especially those requiring autonomy, are potential beneficiaries of evolvable hardware. For example, robotic drilling from a mobile platform requires high-bandwidth controller circuits that are difficult to design. In this paper, we present automated design techniques based on evolutionary search that could potentially be used in such applications. First, we present a method of automatically generating analog circuit designs using evolutionary search and a circuit construction language. Our system allows circuit size (number of devices), circuit topology, and device values to be evolved. Using a parallel genetic algorithm, we present experimental results for five design tasks. Second, we investigate the use of coevolution in automated circuit design. We examine fitness evaluation by comparing the effectiveness of four fitness schedules. The results indicate that solution quality is highest with static and co-evolving fitness schedules as compared to the other two dynamic schedules. We discuss these results and offer two possible explanations for the observed behavior: retention of useful information, and alignment of problem difficulty with circuit proficiency.

Ewald method for polytropic potentials in arbitrary dimensionality

NASA Astrophysics Data System (ADS)

Osychenko, O. N.; Astrakharchik, G. E.; Boronat, J.

2012-02-01

The Ewald summation technique is generalized to power-law 1/| r | k potentials in three-, two- and one-dimensional geometries with explicit formulae for all the components of the sums. The cases of short-range, long-range and 'marginal' interactions are treated separately. The jellium model, as a particular case of a charge-neutral system, is discussed and the explicit forms of the Ewald sums for such a system are presented. A generalized form of the Ewald sums for a non-cubic (non-square) simulation cell for three- (two-) dimensional geometry is obtained and its possible field of application is discussed. A procedure for the optimization of the involved parameters in actual simulations is developed and an example of its application is presented.

POTENTIAL IMPACTS OF GENOMICS ON EPA REGULATORY AND RISK ASSESSMENT APPLICATIONS

EPA Science Inventory

Gallagher, Kathryn and William Benson. In press. Potential Impacts of Genomics on EPA Regulatory and Risk Assessment (Abstract). To be presented at the EPA Science Forum: Healthy Communities and Ecosystems, 1-3 June 2004, Washington, DC. 1 p. (ERL,GB R991).

Advances in ge...

The role of superconductivity in the Space Program: An assessment of present capabilities and future potential

NASA Technical Reports Server (NTRS)

Sullivan, D. B. (Editor)

1978-01-01

Technical subject areas discussed include: (1) high field magnets; (2) magnetometers; (3) digital electronics; (4) high frequency detectors; (5) instruments related to gravitational studies; and (6) ultra high Q cavities. Applications of superconductivity which are of potential interest to NASA were identified.

Telehealth innovations in health education and training.

PubMed

Conde, José G; De, Suvranu; Hall, Richard W; Johansen, Edward; Meglan, Dwight; Peng, Grace C Y

2010-01-01

Telehealth applications are increasingly important in many areas of health education and training. In addition, they will play a vital role in biomedical research and research training by facilitating remote collaborations and providing access to expensive/remote instrumentation. In order to fulfill their true potential to leverage education, training, and research activities, innovations in telehealth applications should be fostered across a range of technology fronts, including online, on-demand computational models for simulation; simplified interfaces for software and hardware; software frameworks for simulations; portable telepresence systems; artificial intelligence applications to be applied when simulated human patients are not options; and the development of more simulator applications. This article presents the results of discussion on potential areas of future development, barries to overcome, and suggestions to translate the promise of telehealth applications into a transformed environment of training, education, and research in the health sciences.

Chitosan: An Update on Potential Biomedical and Pharmaceutical Applications

PubMed Central

Cheung, Randy Chi Fai; Ng, Tzi Bun; Wong, Jack Ho; Chan, Wai Yee

2015-01-01

Chitosan is a natural polycationic linear polysaccharide derived from chitin. The low solubility of chitosan in neutral and alkaline solution limits its application. Nevertheless, chemical modification into composites or hydrogels brings to it new functional properties for different applications. Chitosans are recognized as versatile biomaterials because of their non-toxicity, low allergenicity, biocompatibility and biodegradability. This review presents the recent research, trends and prospects in chitosan. Some special pharmaceutical and biomedical applications are also highlighted. PMID:26287217

A Historical Review of Brayton and Stirling Power Conversion Technologies for Space Applications

NASA Technical Reports Server (NTRS)

Mason, Lee S.; Schreiber, Jeffrey G.

2007-01-01

Dynamic power conversion technologies, such as closed Brayton and free-piston Stirling, offer many advantages for space power applications including high efficiency, long life, and attractive scaling characteristics. This paper presents a historical review of Brayton and Stirling power conversion technology for space and discusses on-going development activities in order to illustrate current technology readiness. The paper also presents a forecast of potential future space uses of these power technologies.

Space Shuttle Debris Transport

NASA Technical Reports Server (NTRS)

Gomez, Reynaldo J., III

2010-01-01

This slide presentation reviews the assessment of debris damage to the Space Shuttle, and the use of computation to assist in the space shuttle applications. The presentation reviews the sources of debris, a mechanism for determining the probability of damaging debris impacting the shuttle, tools used, eliminating potential damaging debris sources, the use of computation to assess while inflight damage, and a chart showing the applications that have been used on increasingly powerful computers simulate the shuttle and the debris transport.

10 CFR 473.10 - Required information from applicant.

Code of Federal Regulations, 2010 CFR

2010-01-01

... production potential by presenting information showing a significant intervening technological advance, promising conceptual innovation, or other special consideration; (d) Provide— (1) An assurance that the...

10 CFR 473.10 - Required information from applicant.

Code of Federal Regulations, 2011 CFR

2011-01-01

... production potential by presenting information showing a significant intervening technological advance, promising conceptual innovation, or other special consideration; (d) Provide— (1) An assurance that the...

The Development of Titanium Alloys for Application in the Space Shuttle Main Engine

NASA Technical Reports Server (NTRS)

Halchak, John A.; Jerman, Gregory A.; Zimmerman, Frank R.

2010-01-01

The high-strength-to-weight ratio of titanium alloys, particularly at cryogenic temperatures, make them attractive for application in rocket engines - offering the potential of superior performance while minimizing component weight. This was particularly attractive for rotating components, such as pump impellers, where titanium alloys presented the potential to achieve a major advance in rotational tip speed, with a reduction in stages and resultant saving in pump weight and complexity. The investigation into titanium alloys for application in cryogenic turbopumps began in the early 1960's. However, it was found that the reactivity of titanium limited applications and produced unique processing challenges. Specialized chemical compositions and processing techniques had to be developed. A substantial amount of material properties testing and trials in experimental turbopumps occurred, ultimately leading to application in the Space Shuttle Main Engine. One particular alloy stood out for use at liquid hydrogen temperatures, Ti-5Al-2.5Sn ELI. This alloy was employed for several critical components. This presentation deals with the development effort, the challenges that were encountered and operational experiences with Ti-5Al-2.5Sn ELI in the SSME.

Advanced Technologies as Educational Tools in Science: Concepts, Applications, and Issues. Monograph Series Number 8.

ERIC Educational Resources Information Center

Kumar, David D.; And Others

Systems incorporating two advanced technologies, hypermedia systems and intelligent tutors, are examined with respect to their potential impact on science education. The conceptual framework underlying these systems is discussed first. Applications of systems are then presented with examples of each in operation within the context of science…

U-ALS: A Ubiquitous Learning Environment

ERIC Educational Resources Information Center

Piovesan, Sandra Dutra; Passerino, Liliana Maria; Medina, Roseclea Duarte

2012-01-01

The diffusion of the use of the learning virtual environments presents a great potential for the development of an application which meet the necessities in the education area. In view of the importance of a more dynamic application and that can adapt itself continuously to the students' necessities, the "U-ALS" (Ubiquitous Adapted Learning…

Carbon fiber study

NASA Technical Reports Server (NTRS)

1977-01-01

A coordinated Federal Government action plan for dealing with the potential problems arising from the increasing use of graphite fiber reinforced composite materials in both military and civilian applications is presented. The required dissemination of declassified information and an outline of government actions to minimize the social and economic consequences of proliferated composite materials applications were included.

Videogame-Like Applications to Enhance Autonomous Learning

ERIC Educational Resources Information Center

Berns, Anke; Valero-Franco, Concepción

2013-01-01

This paper presents the results of an ongoing study which has been carried out with a group of German Foreign Language students at the University of Cadiz since 2012. The purpose of the study was to analyze the impact of videogame-like applications on foreign language learning and their motivational potential to increase learning beyond the…

Guided wave opto-acoustic device

DOEpatents

Jarecki, Jr., Robert L.; Rakich, Peter Thomas; Camacho, Ryan; Shin, Heedeuk; Cox, Jonathan Albert; Qiu, Wenjun; Wang, Zheng

2016-02-23

The various technologies presented herein relate to various hybrid phononic-photonic waveguide structures that can exhibit nonlinear behavior associated with traveling-wave forward stimulated Brillouin scattering (forward-SBS). The various structures can simultaneously guide photons and phonons in a suspended membrane. By utilizing a suspended membrane, a substrate pathway can be eliminated for loss of phonons that suppresses SBS in conventional silicon-on-insulator (SOI) waveguides. Consequently, forward-SBS nonlinear susceptibilities are achievable at about 3000 times greater than achievable with a conventional waveguide system. Owing to the strong phonon-photon coupling achievable with the various embodiments, potential application for the various embodiments presented herein cover a range of radiofrequency (RF) and photonic signal processing applications. Further, the various embodiments presented herein are applicable to applications operating over a wide bandwidth, e.g. 100 MHz to 50 GHz or more.

Control of Aedes albopictus with attractive toxic sugar baits (ATSB) and potential impact on non-target organisms in St. Augustine, Florida

PubMed Central

Revay, Edita E.; Müller, Gunter C.; Qualls, Whitney A.; Kline, Daniel; Naranjo, Diana P.; Arheart, Kristopher L.; Kravchenko, Vasiliy D.; Yfremova, Zoya; Hausmann, Axel; Beier, John C.; Schlein, Yosef; Xue, Rui-De

2013-01-01

The purpose of this study was to test the efficacy of bait stations and foliar applications containing attractive toxic sugar baits (ATSB) and eugenol to control Aedes albopictus. At the same time the potential impact of these control methods was evaluated on non-target organisms. The study was conducted at five tire sites in St. Augustine, Florida. Aedes albopictus populations were significantly reduced with ATSB-eugenol applications applied directly to non-flowering vegetation and as bait stations compared with non-attractive sugar baits and control. The application of ATSB made to non-flowering vegetation resulted in more significant reductions of mosquito populations compared to the application of ATSB presented in a bait station. Over 5.5% of the non-targets were stained in the flowering vegetation application site. However, when the attractive sugar bait application was made to non-flowering vegetation or presented in bait stations the impact on non-target insects was very low for all non-target orders as only 0.6% of the individual insects were stained with the dye from the sugar solutions, respectively. There were no significant differences between the staining of mosquitoes collected in flowering vegetation (206/1000) or non-flowering vegetation (242/1000) sites during the non-target evaluation. Our field studies support the use of eugenol as an active ingredient for controlling the dengue vector Ae. albopictus when used as an ATSB toxin and demonstrates potential use in sub-tropical and tropical environments for dengue control. PMID:24122115

OpenGL in Multi-User Web-Based Applications

NASA Astrophysics Data System (ADS)

Szostek, K.; Piórkowski, A.

In this article construction and potential of OpenGL multi-user web-based application are presented. The most common technologies like: .NET ASP, Java and Mono were used with specific OpenGL libraries to visualize tree-dimensional medical data. The most important conclusion of this work is that server side applications can easily take advantage of fast GPU and produce efficient results of advanced computation just like the visualization.

Health Effects Associated with Wastewater Treatment and Disposal.

ERIC Educational Resources Information Center

Kowal, N. E.; Pahren, H. R.

1978-01-01

Presents a literature review of the potential health effects associated with: (1) wastewater treatment plants; (2) land application of municipal wastewater; and (3) use of renovated water. This review covers the publications of 1976-77. A list of 96 references is also presented. (HM)

Nano-Electronics and Bio-Electronics

NASA Technical Reports Server (NTRS)

Srivastava, Deepak; Kwak, Dochan (Technical Monitor)

2001-01-01

Viewgraph presentation on Nano-Electronics and Bio-Electronics is discussed. Topics discussed include: NASA Ames nanotechnology program, Potential Carbon Nanotube (CNT) application, CNT synthesis,Computational Nanotechnology, and protein nanotubes.

Extended resolvent and inverse scattering with an application to KPI

NASA Astrophysics Data System (ADS)

Boiti, M.; Pempinelli, F.; Pogrebkov, A. K.; Prinari, B.

2003-08-01

We present in detail an extended resolvent approach for investigating linear problems associated to 2+1 dimensional integrable equations. Our presentation is based as an example on the nonstationary Schrödinger equation with potential being a perturbation of the one-soliton potential by means of a decaying two-dimensional function. Modification of the inverse scattering theory as well as properties of the Jost solutions and spectral data as follows from the resolvent approach are given.

Application of a Chimera Full Potential Algorithm for Solving Aerodynamic Problems

NASA Technical Reports Server (NTRS)

Holst, Terry L.; Kwak, Dochan (Technical Monitor)

1997-01-01

A numerical scheme utilizing a chimera zonal grid approach for solving the three dimensional full potential equation is described. Special emphasis is placed on describing the spatial differencing algorithm around the chimera interface. Results from two spatial discretization variations are presented; one using a hybrid first-order/second-order-accurate scheme and the second using a fully second-order-accurate scheme. The presentation is highlighted with a number of transonic wing flow field computations.

The comparative study of bulk magneto-phonon and magnetic polaritons of lateral antiferromagnetic superlattices for potential THz applications

NASA Astrophysics Data System (ADS)

Ta, Jin-Xing; Han, Yu; Lan, Cheng

2016-02-01

Bulk magneto-phonon and magnetic polaritons of lateral antiferromagnetic superlattices for potential THz applications have been investigated in the framework of the effective medium theory. The dispersion relations applied for the system are displayed. In contrast with lateral FeF2/SiO2 superlattice, some fascinating polariton modes with negative group velocity signifying photonic band gap scenarios and attractive optical properties are observed from the numerical results presented with the example, lateral FeF2/TlBr superlattice.

Carbon Fiber Reinforced Ceramic Composites for Propulsion Applications

NASA Technical Reports Server (NTRS)

Shivakumar, Kunigal; Argade, Shyam

2003-01-01

This report presents a critical review of the processing techniques for fabricating continuous fiber-reinforced CMCs for possible applications at elevated temperatures. Some of the issues affecting durability of the composite materials such as fiber coatings and cracking of the matrix because of shrinkage in PIP-process are also examined. An assessment of the potential inexpensive processes is also provided. Finally three potential routes of manufacturing C/SiC composites using a technology that NC A&T developed for carbon/carbon composites are outlined. Challenges that will be encountered are also listed.

Applications of nutrient profiling: potential role in diet-related chronic disease prevention and the feasibility of a core nutrient-profiling system.

PubMed

Sacks, G; Rayner, M; Stockley, L; Scarborough, P; Snowdon, W; Swinburn, B

2011-03-01

A number of different nutrient-profiling models have been proposed and several applications of nutrient profiling have been identified. This paper outlines the potential role of nutrient-profiling applications in the prevention of diet-related chronic disease (DRCD), and considers the feasibility of a core nutrient-profiling system, which could be modified for purpose, to underpin the multiple potential applications in a particular country. The 'Four 'P's of Marketing' (Product, Promotion, Place and Price) are used as a framework for identifying and for classifying potential applications of nutrient profiling. A logic pathway is then presented that can be used to gauge the potential impact of nutrient-profiling interventions on changes in behaviour, changes in diet and, ultimately, changes in DRCD outcomes. The feasibility of a core nutrient-profiling system is assessed by examining the implications of different model design decisions and their suitability to different purposes. There is substantial scope to use nutrient profiling as part of the policies for the prevention of DRCD. A core nutrient-profiling system underpinning the various applications is likely to reduce discrepancies and minimise the confusion for regulators, manufacturers and consumers. It seems feasible that common elements, such as a standard scoring method, a core set of nutrients and food components, and defined food categories, could be incorporated as part of a core system, with additional application-specific criteria applying. However, in developing and in implementing such a system, several country-specific contextual and technical factors would need to be balanced.

Combinatorial nanodiamond in pharmaceutical and biomedical applications.

PubMed

Lim, Dae Gon; Prim, Racelly Ena; Kim, Ki Hyun; Kang, Eunah; Park, Kinam; Jeong, Seong Hoon

2016-11-30

One of the newly emerging carbon materials, nanodiamond (ND), has been exploited for use in traditional electric materials and this has extended into biomedical and pharmaceutical applications. Recently, NDs have attained significant interests as a multifunctional and combinational drug delivery system. ND studies have provided insights into granting new potentials with their wide ranging surface chemistry, complex formation with biopolymers, and combination with biomolecules. The studies that have proved ND inertness, biocompatibility, and low toxicity have made NDs much more feasible for use in real in vivo applications. This review gives an understanding of NDs in biomedical engineering and pharmaceuticals, focusing on the classified introduction of ND/drug complexes. In addition, the diverse potential applications that can be obtained with chemical modification are presented. Copyright © 2016 Elsevier B.V. All rights reserved.

A see through future: augmented reality and health information systems.

PubMed

Monkman, Helen; Kushniruk, Andre W

2015-01-01

Augmented Reality (AR) is a method whereby virtual objects are superimposed on the real world. AR technology is becoming increasingly accessible and affordable and it has many potential health applications. This paper discusses current research on AR health applications such as medical education and medical practice. Some of the potential future uses for this technology (e.g., health information systems, consumer health applications) will also be presented. Additionally, there will be a discussion outlining some of usability and human factors challenges associated with AR in healthcare. It is expected that AR will become increasingly prevalent in healthcare; however, further investigation is required to demonstrate that they provide benefits over traditional methods. Moreover, AR applications must be thoroughly tested to ensure they do not introduce new errors into practice and have patient safety implications.

Interpretation and use of natriuretic peptides in non-congestive heart failure settings.

PubMed

Tsai, Shih-Hung; Lin, Yen-Yue; Chu, Shi-Jye; Hsu, Ching-Wang; Cheng, Shu-Meng

2010-03-01

Natriuretic peptides (NPs) have been found to be useful markers in differentiating acute dyspneic patients presenting to the emergency department (ED) and emerged as potent prognostic markers for patients with congestive heart failure (CHF). The best-established and widely used clinical application of BNP and NT-proBNP testing is for the emergent diagnosis of CHF in patients presenting with acute dyspnea. Nevertheless, elevated NPs levels can be found in many circumstances involving left ventricular (LV) dysfunction or hypertrophy; right ventricular (RV) dysfunction secondary to pulmonary diseases; cardiac inflammatory or infectious diseases; endocrinology diseases and high output status without decreased LV ejection fraction. Even in the absence of significant clinical evidence of volume overload or LV dysfunction, markedly elevated NP levels can be found in patients with multiple comorbidities with a certain degree of prognostic value. Potential clinical applications of NPs are expanded accompanied by emerging reports regarding screening the presence of secondary cardiac dysfunction; monitoring the therapeutic responses, risk stratifications and providing prognostic values in many settings. Clinicians need to have expanded knowledge regarding the interpretation of elevated NPs levels and potential clinical applications of NPs. Clinicians should recognize that currently the only reasonable application for routine practice is limited to differentiation of acute dyspnea, rule-out-diagnostic-tests, monitoring of therapeutic responses and prognosis of acute or decompensated CHF. The rationales as well the potential applications of NPs in these settings are discussed in this review article.

Interpretation and Use of Natriuretic Peptides in Non-Congestive Heart Failure Settings

PubMed Central

Lin, Yen-Yue; Chu, Shi-Jye; Hsu, Ching-Wang; Cheng, Shu-Meng

2010-01-01

Natriuretic peptides (NPs) have been found to be useful markers in differentiating acute dyspneic patients presenting to the emergency department (ED) and emerged as potent prognostic markers for patients with congestive heart failure (CHF). The best-established and widely used clinical application of BNP and NT-proBNP testing is for the emergent diagnosis of CHF in patients presenting with acute dyspnea. Nevertheless, elevated NPs levels can be found in many circumstances involving left ventricular (LV) dysfunction or hypertrophy; right ventricular (RV) dysfunction secondary to pulmonary diseases; cardiac inflammatory or infectious diseases; endocrinology diseases and high output status without decreased LV ejection fraction. Even in the absence of significant clinical evidence of volume overload or LV dysfunction, markedly elevated NP levels can be found in patients with multiple comorbidities with a certain degree of prognostic value. Potential clinical applications of NPs are expanded accompanied by emerging reports regarding screening the presence of secondary cardiac dysfunction; monitoring the therapeutic responses, risk stratifications and providing prognostic values in many settings. Clinicians need to have expanded knowledge regarding the interpretation of elevated NPs levels and potential clinical applications of NPs. Clinicians should recognize that currently the only reasonable application for routine practice is limited to differentiation of acute dyspnea, rule-out-diagnostic-tests, monitoring of therapeutic responses and prognosis of acute or decompensated CHF. The rationales as well the potential applications of NPs in these settings are discussed in this review article. PMID:20191004

Using SAR satellite data time series for regional glacier mapping

NASA Astrophysics Data System (ADS)

Winsvold, Solveig H.; Kääb, Andreas; Nuth, Christopher; Andreassen, Liss M.; van Pelt, Ward J. J.; Schellenberger, Thomas

2018-03-01

With dense SAR satellite data time series it is possible to map surface and subsurface glacier properties that vary in time. On Sentinel-1A and RADARSAT-2 backscatter time series images over mainland Norway and Svalbard, we outline how to map glaciers using descriptive methods. We present five application scenarios. The first shows potential for tracking transient snow lines with SAR backscatter time series and correlates with both optical satellite images (Sentinel-2A and Landsat 8) and equilibrium line altitudes derived from in situ surface mass balance data. In the second application scenario, time series representation of glacier facies corresponding to SAR glacier zones shows potential for a more accurate delineation of the zones and how they change in time. The third application scenario investigates the firn evolution using dense SAR backscatter time series together with a coupled energy balance and multilayer firn model. We find strong correlation between backscatter signals with both the modeled firn air content and modeled wetness in the firn. In the fourth application scenario, we highlight how winter rain events can be detected in SAR time series, revealing important information about the area extent of internal accumulation. In the last application scenario, averaged summer SAR images were found to have potential in assisting the process of mapping glaciers outlines, especially in the presence of seasonal snow. Altogether we present examples of how to map glaciers and to further understand glaciological processes using the existing and future massive amount of multi-sensor time series data.

Synthesis, characterization, bioactivity and potential application of phenolic acid grafted chitosan: A review.

PubMed

Liu, Jun; Pu, Huimin; Liu, Shuang; Kan, Juan; Jin, Changhai

2017-10-15

In recent years, increasing attention has been paid to the grafting of phenolic acid onto chitosan in order to enhance the bioactivity and widen the application of chitosan. Here, we present a comprehensive overview on the recent advances of phenolic acid grafted chitosan (phenolic acid-g-chitosan) in many aspects, including the synthetic method, structural characterization, biological activity, physicochemical property and potential application. In general, four kinds of techniques including carbodiimide based coupling, enzyme catalyzed grafting, free radical mediated grafting and electrochemical methods are frequently used for the synthesis of phenolic acid-g-chitosan. The structural characterization of phenolic acid-g-chitosan can be determined by several instrumental methods. The physicochemical properties of chitosan are greatly altered after grafting. As compared with chitosan, phenolic acid-g-chitosan exhibits enhanced antioxidant, antimicrobial, antitumor, anti-allergic, anti-inflammatory, anti-diabetic and acetylcholinesterase inhibitory activities. Notably, phenolic acid-g-chitosan shows potential applications in many fields as coating agent, packing material, encapsulation agent and bioadsorbent. Copyright © 2017 Elsevier Ltd. All rights reserved.

A review of the economic implications of the National Academy of Engineering 1974 study of the potential application of space systems

NASA Technical Reports Server (NTRS)

1975-01-01

User benefits resulting from the application of space systems to previously described application areas were identified, and methods to assign priorities to application areas and to quantify the benefits were described. The following areas were selected for in-depth review: communications, materials processing in space, weather and climate, and institutional arrangements for space applications. Recommendations concerning studies that should be undertaken to develop a more precise understanding of the source and magnitude of the realizable economic benefits were also presented.

Aerospace Applications of Magnetic Suspension Technology, part 2

NASA Technical Reports Server (NTRS)

Groom, Nelson J. (Editor); Britcher, Colin P. (Editor)

1991-01-01

In order to examine the state of technology of all areas of magnetic suspension with potential aerospace applications, and to review related recent developments in sensors and control approaches, superconducting technology, and design/implementation practices, a workshop was held at NASA-Langley. Areas of concern are pointing and isolation systems, microgravity and vibration isolation, bearing applications, wind tunnel model suspension systems, large gap magnetic suspension systems, controls, rotating machinery, science and applications of superconductivity, and sensors. Papers presented are included.

Applications of aerospace technology in biology and medicine

NASA Technical Reports Server (NTRS)

Brown, J. N.

1974-01-01

The results of the medically related activities of the NASA Application Team Program at the Research Triangle Institute are presented. The RTI team, a multidisciplinary team of scientists and engineers, acted as an information and technology interface between NASA and individuals, institutions, and agencies involved in biomedical research and clinical medicine. The Team has identified 40 new problems for investigation, has accomplished 7 technology applications, 6 potential technology application, 4 impacts, has closed 54 old problems, and has a total of 47 problems under active investigation.

Space Station Freedom automation and robotics: An assessment of the potential for increased productivity

NASA Technical Reports Server (NTRS)

Weeks, David J.; Zimmerman, Wayne F.; Swietek, Gregory E.; Reid, David H.; Hoffman, Ronald B.; Stammerjohn, Lambert W., Jr.; Stoney, William; Ghovanlou, Ali H.

1990-01-01

This report presents the results of a study performed in support of the Space Station Freedom Advanced Development Program, under the sponsorship of the Space Station Engineering (Code MT), Office of Space Flight. The study consisted of the collection, compilation, and analysis of lessons learned, crew time requirements, and other factors influencing the application of advanced automation and robotics, with emphasis on potential improvements in productivity. The lessons learned data collected were based primarily on Skylab, Spacelab, and other Space Shuttle experiences, consisting principally of interviews with current and former crew members and other NASA personnel with relevant experience. The objectives of this report are to present a summary of this data and its analysis, and to present conclusions regarding promising areas for the application of advanced automation and robotics technology to the Space Station Freedom and the potential benefits in terms of increased productivity. In this study, primary emphasis was placed on advanced automation technology because of its fairly extensive utilization within private industry including the aerospace sector. In contrast, other than the Remote Manipulator System (RMS), there has been relatively limited experience with advanced robotics technology applicable to the Space Station. This report should be used as a guide and is not intended to be used as a substitute for official Astronaut Office crew positions on specific issues.

Introducing ZORA to Children with Severe Physical Disabilities.

PubMed

van den Heuvel, Renée; Lexis, Monique; de Witte, Luc

2017-01-01

The aim of the present study was to explore the potential of a ZORA-robot based intervention in rehabilitation and special education for children with (severe) physical disabilities from the professionals perspective. The qualitative results of this study will be presented. Professionals indicated meaningful application possibilities for ZORA. Overall, ZORA was able to improve motivation, concentration, taking initiative and attention span. Three domains could be identified to be most promising for application of ZORA: (re)learning of movement skills, cognitive skills and communication/social interaction skills.

Literature concerning control and display technology applicable to the Orbital Maneuvering Vehicle (OMV)

NASA Technical Reports Server (NTRS)

1990-01-01

A review is presented of the literature concerning control and display technology that is applicable to the Orbital Maneuvering Vehicle (OMV), a system being developed by NASA that will enable the user to remotely pilot it during a mission in space. In addition to the general review, special consideration is given to virtual image displays and their potential for use in the system, and a preliminary partial task analysis of the user's functions is also presented.

Cyber Technology for Materials and Structures in Aeronautics and Aerospace

NASA Technical Reports Server (NTRS)

Pipes, R. Byron

2002-01-01

The evolution of composites applications in aeronautics from 1970 to the present is discussed. The barriers and challenges to economic application and to certification are presented and recommendations for accelerated development are outlined. The potential benefits of emerging technologies to aeronautics and their foundation in composite materials are described and the resulting benefits in vehicle take off gross weight are quantified. Finally, a 21st century vision for aeronautics in which human mobility is increased by an order of magnitude is articulated.

Cannabis, Cannabinoids, and Cerebral Metabolism: Potential Applications in Stroke and Disorders of the Central Nervous System.

PubMed

Latorre, Julius Gene S; Schmidt, Elena B

2015-09-01

No compound has generated more attention in both the scientific and recently in the political arena as much as cannabinoids. These diverse groups of compounds referred collectively as cannabinoids have both been vilified due to its dramatic and potentially harmful psychotropic effects and glorified due to its equally dramatic and potential application in a number of acute and chronic neurological conditions. Previously illegal to possess, cannabis, the plant where natural form of cannabinoids are derived, is now accepted in a growing number of states for medicinal purpose, and some even for recreational use, increasing opportunities for more scientific experimentation. The purpose of this review is to summarize the growing body of literature on cannabinoids and to present an overview of our current state of knowledge of the human endocannabinoid system in the hope of defining the future of cannabinoids and its potential applications in disorders of the central nervous system, focusing on stroke.

BIOPEP database and other programs for processing bioactive peptide sequences.

PubMed

Minkiewicz, Piotr; Dziuba, Jerzy; Iwaniak, Anna; Dziuba, Marta; Darewicz, Małgorzata

2008-01-01

This review presents the potential for application of computational tools in peptide science based on a sample BIOPEP database and program as well as other programs and databases available via the World Wide Web. The BIOPEP application contains a database of biologically active peptide sequences and a program enabling construction of profiles of the potential biological activity of protein fragments, calculation of quantitative descriptors as measures of the value of proteins as potential precursors of bioactive peptides, and prediction of bonds susceptible to hydrolysis by endopeptidases in a protein chain. Other bioactive and allergenic peptide sequence databases are also presented. Programs enabling the construction of binary and multiple alignments between peptide sequences, the construction of sequence motifs attributed to a given type of bioactivity, searching for potential precursors of bioactive peptides, and the prediction of sites susceptible to proteolytic cleavage in protein chains are available via the Internet as are other approaches concerning secondary structure prediction and calculation of physicochemical features based on amino acid sequence. Programs for prediction of allergenic and toxic properties have also been developed. This review explores the possibilities of cooperation between various programs.

In-Space Assembly Capability Assessment for Potential Human Exploration and Science Applications

NASA Technical Reports Server (NTRS)

Jefferies, Sharon A.; Jones, Christopher A.; Arney, Dale C.; Stillwagen, Frederic H.; Chai, Patrick R.; Hutchinson, Craig D.; Stafford, Matthew A.; Moses, Robert W.; Dempsey, James A.; Rodgers, Erica M.;

Telehealth Innovations in Health Education and Training

PubMed Central

De, Suvranu; Hall, Richard W.; Johansen, Edward; Meglan, Dwight; Peng, Grace C.Y.

2010-01-01

Abstract Telehealth applications are increasingly important in many areas of health education and training. In addition, they will play a vital role in biomedical research and research training by facilitating remote collaborations and providing access to expensive/remote instrumentation. In order to fulfill their true potential to leverage education, training, and research activities, innovations in telehealth applications should be fostered across a range of technology fronts, including online, on-demand computational models for simulation; simplified interfaces for software and hardware; software frameworks for simulations; portable telepresence systems; artificial intelligence applications to be applied when simulated human patients are not options; and the development of more simulator applications. This article presents the results of discussion on potential areas of future development, barries to overcome, and suggestions to translate the promise of telehealth applications into a transformed environment of training, education, and research in the health sciences. PMID:20155874

Undergraduate Experiment with Fractal Diffraction Gratings

ERIC Educational Resources Information Center

Monsoriu, Juan A.; Furlan, Walter D.; Pons, Amparo; Barreiro, Juan C.; Gimenez, Marcos H.

2011-01-01

We present a simple diffraction experiment with fractal gratings based on the triadic Cantor set. Diffraction by fractals is proposed as a motivating strategy for students of optics in the potential applications of optical processing. Fraunhofer diffraction patterns are obtained using standard equipment present in most undergraduate physics…

Bacteriocinogenic Lactococcus lactis subsp. lactis DF04Mi isolated from goat milk: evaluation of the probiotic potential.

PubMed

Furtado, Danielle N; Todorov, Svetoslav D; Landgraf, Mariza; Destro, Maria T; Franco, Bernadette D G M

2014-01-01

Lactic acid bacteria capable of producing bacteriocins and presenting probiotic potential open innovative technological applications in the dairy industry. In this study, a bacteriocinogenic strain (Lactococcus lactis subsp. lactis DF4Mi) was isolated from goat milk, and studied for its probiotic potential. Lc. lactis DF4Mi was resistant to acidic pH and oxbile, presented co-aggregation with Listeria monocytogenes, and was not affected by several drugs from different generic groups, being sensitive to most tested antibiotics. These properties indicate that this Lc. lactis strain can be used for enhancement of dairy foods safety and quality, in combination with potential probiotic properties.

Supersonic full-potential methods for missile body analysis

NASA Technical Reports Server (NTRS)

Pittman, James L.

1992-01-01

Accounts are presented of representative applications to missile bodies of arbitrary shape of methods based on the steady form of the full potential equation. The NCOREL and SIMP full-potential codes are compared, and their results are evaluated for the cases of an arrow wing and a wing-body configuration. Attention is given to the effect of cross-sectional and longitudinal geometries. Comparisons of surface pressure and longitudinal force and moment data for circular and elliptic bodies have shown that the full-potential methods yielded excellent results in attached-flow conditions. Results are presented for a conical star body, waveriders, the Shuttle Orbiter, and a highly swept wing-body cruising at Mach 4.

Fiberoptic sensors for rocket engine applications

NASA Technical Reports Server (NTRS)

Ballard, R. O.

1992-01-01

A research effort was completed to summarize and evaluate the current level of technology in fiberoptic sensors for possible applications in integrated control and health monitoring (ICHM) systems in liquid propellant engines. The environment within a rocket engine is particuarly severe with very high temperatures and pressures present combined with extremely rapid fluid and gas flows, and high-velocity and high-intensity acoustc waves. Application of fiberoptic technology to rocket engine health monitoring is a logical evolutionary step in ICHM development and presents a significant challenge. In this extremely harsh environment, the additional flexibility of fiberoptic techniques to augment conventional sensor technologies offer abundant future potential.

Production of a bioemulsifier with potential application in the food industry.

PubMed

Campos, Jenyffer M; Stamford, Tânia L M; Sarubbo, Leonie A

2014-03-01

Biosurfactants are of considerable interest due to their biodegradability, low degree of toxicity, and diverse applications. However, the high production costs involved in the acquisition of biosurfactants underscore the need for optimization of the production process to enable viable application on an industrial scale. The aims of the present study were to select a species of Candida that produces a biosurfactant with the greatest emulsifying potential and to investigate the influence of components of the production medium and cultivation conditions. Candida utilis achieved the lowest surface tension (35.53 mN/m), best emulsification index (73%), and highest yield (12.52 g/l) in a medium containing waste canola frying oil as the carbon source and ammonium nitrate as the nitrogen source. The best combination of medium components and cultivation conditions was 6% (w/v) glucose, 6% (w/v) waste canola frying oil, 0.2% (w/v) ammonium nitrate, 0.3% (w/v) yeast extract, 150 rpm, 1% inoculum (w/v), and 88 h of fermentation. The greatest biosurfactant production and the lowest surface tension were achieved in the first 24 h of production, and the maximum biomass production was recorded at 72 h. The biosurfactant produced from C. utilis under the conditions investigated in the present study has a potential to be a bioemulsifier for application in the food industry.

Snakin: Structure, Roles and Applications of a Plant Antimicrobial Peptide.

PubMed

Oliveira-Lima, Marx; Benko-Iseppon, Ana Maria; Neto, Jose Ribamar Costa Ferreira; Rodriguez-Decuadro, Susana; Kido, Ederson Akio; Crovella, Sergio; Pandolfi, Valesca

2017-01-01

Snakins are plant antimicrobial peptides (AMPs) of the Snakin/GASA family, formed by three distinct regions: an N-terminal signal peptide; a variable site; and the GASA domain in the Cterminal region composed by twelve conserved cysteine residues that contribute to the biochemical stability of the molecule. These peptides are known to play different roles in response to a variety of biotic (i.e., induced by bacteria, fungi and nematode pathogens) and abiotic (salinity, drought and ROS) stressors, as well as in crosstalk promoted by plant hormones, with emphasis on abscisic and salicylic acid (ABA and SA, respectively). Such properties make snakin/GASA members promising biotechnological sources for potential therapeutic and agricultural applications. However, information regarding their tertiary structure, mode of action and function are not yet completely elucidated. The present review presents aspects of snakin structure, expression, functional studies and perspectives about the potential applications for agricultural and medical purposes. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Finite difference methods for the solution of unsteady potential flows

NASA Technical Reports Server (NTRS)

Caradonna, F. X.

1985-01-01

A brief review is presented of various problems which are confronted in the development of an unsteady finite difference potential code. This review is conducted mainly in the context of what is done for a typical small disturbance and full potential methods. The issues discussed include choice of equation, linearization and conservation, differencing schemes, and algorithm development. A number of applications including unsteady three-dimensional rotor calculation, are demonstrated.

BioMEMS –Advancing the Frontiers of Medicine

PubMed Central

James, Teena; Mannoor, Manu Sebastian; Ivanov, Dentcho V.

2008-01-01

Biological and medical application of micro-electro-mechanical-systems (MEMS) is currently seen as an area of high potential impact. Integration of biology and microtechnology has resulted in the development of a number of platforms for improving biomedical and pharmaceutical technologies. This review provides a general overview of the applications and the opportunities presented by MEMS in medicine by classifying these platforms according to their applications in the medical field. PMID:27873858

Mission applications of electric propulsion

NASA Technical Reports Server (NTRS)

Atkins, K. L.

1974-01-01

This paper reviews the mission applications of electric propulsion. The energy requirements of candidate high-energy missions gaining in NASA priority are used to highlight the potential of electric propulsion. Mission-propulsion interfaces are examined to point out differences between chemical and electric applications. Brief comparisons between ballistic requirements and capabilities and those of electric propulsion show that electric propulsion is presently the most practical and perhaps the only technology which can accomplish missions with these energy requirements.

The versatile biopolymer chitosan: potential sources, evaluation of extraction methods and applications.

PubMed

Kaur, Surinder; Dhillon, Gurpreet Singh

2014-05-01

Among the biopolymers, chitin and its derivative chitosan (CTS) have been receiving increasing attention. Both are composed of randomly distributed β-(1-4)-linked d-glucosamine and N-acetyl glucosamine units. On commercial scale, CTS is mainly obtained from the crustacean shells. The chemical methods employed for extraction of CTS from crustacean shells are laden with many disadvantages. Waste fungal biomass represents a potential biological source of CTS, in fact with superior physico-chemical properties, such as high degree of deacetylation, low molecular weight, devoid of protein contamination and high bioactivity. Researchers around the globe are attempting to commercialize CTS production and extraction from fungal sources. Fungi are promising and environmentally benign source of CTS and they have the potential to completely replace crustacean-derived CTS. Waste fungal biomass resulting from various pharmaceutical and biotechnological industries is grown on inexpensive agro-industrial wastes and its by-products are a rich and inexpensive source of CTS. CTS is emerging as an important natural polymer having broad range of applications in different fields. In this context, the present review discusses the potential sources of CTS and their advantages and disadvantages. This review also deals with potential applications of CTS in different fields. Finally, the various attributes of CTS sought in different applications are discussed.

Microbial biosurfactants as additives for food industries.

PubMed

Campos, Jenyffer Medeiros; Stamford, Tânia Lúcia Montenegro; Sarubbo, Leonie Asfora; de Luna, Juliana Moura; Rufino, Raquel Diniz; Banat, Ibrahim M

2013-01-01

Microbial biosurfactants with high ability to reduce surface and interfacial surface tension and conferring important properties such as emulsification, detergency, solubilization, lubrication and phase dispersion have a wide range of potential applications in many industries. Significant interest in these compounds has been demonstrated by environmental, bioremediation, oil, petroleum, food, beverage, cosmetic and pharmaceutical industries attracted by their low toxicity, biodegradability and sustainable production technologies. Despite having significant potentials associated with emulsion formation, stabilization, antiadhesive and antimicrobial activities, significantly less output and applications have been reported in food industry. This has been exacerbated by uneconomical or uncompetitive costing issues for their production when compared to plant or chemical counterparts. In this review, biosurfactants properties, present uses and potential future applications as food additives acting as thickening, emulsifying, dispersing or stabilising agents in addition to the use of sustainable economic processes utilising agro-industrial wastes as alternative substrates for their production are discussed. © 2013 American Institute of Chemical Engineers.

The role of fuel cells in NASA's space power systems

NASA Technical Reports Server (NTRS)

Been, J. F.

1979-01-01

A history of the fuel cell technology is presented and compared with NASA's increasing space power requirements. The role of fuel cells is discussed in perspective with other energy storage systems applicable for space using such criteria as type of mission, weight, reliability, costs, etc. Potential applications of space fuel cells with projected technology advances were examined.

Magnetized jet creation using a ring laser and applications

NASA Astrophysics Data System (ADS)

Liang, Edison; Gao, Ian; Lu, Yingchao; Ji, Hantao; Follett, Russ; Froula, Dustin; Tzeferacos, Petros; Lamb, Donald; Bickel, Andrew; Sio, Hong; Li, Chi Kiang; Petrasso, Richard; Wei, Mingsheng; Fu, Wen; Han, Lily

2017-10-01

We have recently demonstrated a new robust platform of magnetized jet creation using 20 OMEGA beams to form a hollow ring. We will present the latest experimental results and their theoretical interpretation, and explore potential applications to laboratory astrophysics, fundamental plasma physics and other areas. We will also discuss the scaling of this platform to future NIF experiments.

Perspective on intelligent avionics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, H.L.

1987-01-01

Technical issues which could potentially limit the capability and acceptibility of expert systems decision-making for avionics applications are addressed. These issues are: real-time AI, mission-critical software, conventional algorithms, pilot interface, knowledge acquisition, and distributed expert systems. Examples from on-going expert system development programs are presented to illustrate likely architectures and applications of future intelligent avionic systems. 13 references.

Perceptions of Polycom Programming for Delivery of Continuing Education to Florida's Licensed Pesticide Applicators

ERIC Educational Resources Information Center

Fishel, Fred; Ferrell, Jason; Vallad, Gary; Price, Jim; Cherry, Ron; Mizell, Russ; Duncan, Larry

2010-01-01

Polycom technology has potential for efficient use of program delivery by Extension educators. A survey of licensed pesticide applicators attending a 1-day event at one of 20 host polycom sites revealed that polycom distance learning is effective for presenting information and learning. Responses also indicated that most of this audience is…

Distributed expert systems for ground and space applications

NASA Technical Reports Server (NTRS)

Buckley, Brian; Wheatcraft, Louis

1992-01-01

Presented here is the Spacecraft Command Language (SCL) concept of the unification of ground and space operations using a distributed approach. SCL is a hybrid software environment borrowing from expert system technology, fifth generation language development, and multitasking operating system environments. Examples of potential uses for the system and current distributed applications of SCL are given.

Evaluation of the Tribological Behavior of Krytox 143AB with Nano-onions

NASA Technical Reports Server (NTRS)

Street, Kenneth W.; Marchetti, Mario; VanderWal, Randy L.; Tomasek, Aaron J.

2003-01-01

Nanoparticles have been widely developed over the past ten years and have found several applications. This work presents the use of carbon nano-onions, i.e. nanoparticles, as a potential additive in an oil for aerospace application. It was shown that these particles can provide adequate lubrication very similar to graphitic material.

A Field Programmable Gate Array Based Software Defined Radio Design for the Space Environment

DTIC Science & Technology

2009-12-01

CHANGING PARAMETERS ......................................................................97 APPENDIX B. ADDITIONAL APPLICATIONS ...Professor Frank Kragh was inspirational and always provided keen insight into the mathematics of signal analysis. Special thanks to Professor...and risk involved with launching a new satellite. [2] An FPGA design with potential for space applications was presented in [3]. This initial SDR

An improved fast multipole method for electrostatic potential calculations in a class of coarse-grained molecular simulations

NASA Astrophysics Data System (ADS)

Poursina, Mohammad; Anderson, Kurt S.

2014-08-01

This paper presents a novel algorithm to approximate the long-range electrostatic potential field in the Cartesian coordinates applicable to 3D coarse-grained simulations of biopolymers. In such models, coarse-grained clusters are formed via treating groups of atoms as rigid and/or flexible bodies connected together via kinematic joints. Therefore, multibody dynamic techniques are used to form and solve the equations of motion of such coarse-grained systems. In this article, the approximations for the potential fields due to the interaction between a highly negatively/positively charged pseudo-atom and charged particles, as well as the interaction between clusters of charged particles, are presented. These approximations are expressed in terms of physical and geometrical properties of the bodies such as the entire charge, the location of the center of charge, and the pseudo-inertia tensor about the center of charge of the clusters. Further, a novel substructuring scheme is introduced to implement the presented far-field potential evaluations in a binary tree framework as opposed to the existing quadtree and octree strategies of implementing fast multipole method. Using the presented Lagrangian grids, the electrostatic potential is recursively calculated via sweeping two passes: assembly and disassembly. In the assembly pass, adjacent charged bodies are combined together to form new clusters. Then, the potential field of each cluster due to its interaction with faraway resulting clusters is recursively calculated in the disassembly pass. The method is highly compatible with multibody dynamic schemes to model coarse-grained biopolymers. Since the proposed method takes advantage of constant physical and geometrical properties of rigid clusters, improvement in the overall computational cost is observed comparing to the tradition application of fast multipole method.

Meteorological satellites: Past, present, and future

NASA Technical Reports Server (NTRS)

1982-01-01

Past developments, accomplishments and future potential of meteorological satellites are discussed. Meteorological satellite design is described in detail. Space platforms and their meteorological applications are discussed. User needs are also discussed.

Voice reaction times with recognition for Commodore computers

NASA Technical Reports Server (NTRS)

Washburn, David A.; Putney, R. Thompson

1990-01-01

Hardware and software modifications are presented that allow for collection and recognition by a Commodore computer of spoken responses. Responses are timed with millisecond accuracy and automatically analyzed and scored. Accuracy data for this device from several experiments are presented. Potential applications and suggestions for improving recognition accuracy are also discussed.

Estimating Solar PV Output Using Modern Space/Time Geostatistics (Presentation)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, S. J.; George, R.; Bush, B.

2009-04-29

This presentation describes a project that uses mapping techniques to predict solar output at subhourly resolution at any spatial point, develop a methodology that is applicable to natural resources in general, and demonstrate capability of geostatistical techniques to predict the output of a potential solar plant.

Managing hazardous waste in the clinical laboratory.

PubMed

Hoeltge, G A

1989-09-01

Clinical laboratories generate wastes that present chemical and biologic hazards. Ignitable, corrosive, reactive, toxic, and infectious potentials must be contained and minimized. A summary of these problems and an overview of the applicable regulations are presented. A checklist of activities to facilitate the annual review of the hazardous waste program is provided.

Flywheel Energy Storage Technology Workshop

NASA Astrophysics Data System (ADS)

Okain, D.; Howell, D.

Advances in recent years of high strength/lightweight materials, high performance magnetic bearings, and power electronics technology has spurred a renewed interest by the transportation, utility, and manufacturing industries in flywheel energy storage (FES) technologies. FES offers several advantages over conventional electrochemical energy storage, such as high specific energy and specific power, fast charging time, long service life, high turnaround efficiency (energy out/energy in), and no hazardous/toxic materials or chemicals are involved. Potential applications of FES units include power supplies for hybrid and electric vehicles, electric vehicle charging stations, space systems, and pulsed power devices. Also, FES units can be used for utility load leveling, uninterruptable power supplies to protect electronic equipment and electrical machinery, and for intermittent wind or photovoltaic energy sources. The purpose of this workshop is to provide a forum to highlight technologies that offer a high potential to increase the performance of FES systems and to discuss potential solutions to overcome present FES application barriers. This document consists of viewgraphs from 27 presentations.

Potential for beneficial application of sulfate reducing bacteria in sulfate containing domestic wastewater treatment.

PubMed

van den Brand, T P H; Roest, K; Chen, G H; Brdjanovic, D; van Loosdrecht, M C M

2015-11-01

The activity of sulfate reducing bacteria (SRB) in domestic wastewater treatment plants (WWTP) is often considered as a problem due to H2S formation and potential related odour and corrosion of materials. However, when controlled well, these bacteria can be effectively used in a positive manner for the treatment of wastewater. The main advantages of using SRB in wastewater treatment are: (1) minimal sludge production, (2) reduction of potential pathogens presence, (3) removal of heavy metals and (4) as pre-treatment of anaerobic digestion. These advantages are accessory to efficient and stable COD removal by SRB. Though only a few studies have been conducted on SRB treatment of domestic wastewater, the many studies performed on industrial wastewater provide information on the potential of SRB in domestic wastewater treatment. A key-parameter analyses literature study comprising pH, organic substrates, sulfate, salt, temperature and oxygen revealed that the conditions are well suited for the application of SRB in domestic wastewater treatment. Since the application of SRB in WWTP has environmental benefits its application is worth considering for wastewater treatment, when sulfate is present in the influent.

A Brain-Computer Interface (BCI) system to use arbitrary Windows applications by directly controlling mouse and keyboard.

PubMed

Spuler, Martin

2015-08-01

A Brain-Computer Interface (BCI) allows to control a computer by brain activity only, without the need for muscle control. In this paper, we present an EEG-based BCI system based on code-modulated visual evoked potentials (c-VEPs) that enables the user to work with arbitrary Windows applications. Other BCI systems, like the P300 speller or BCI-based browsers, allow control of one dedicated application designed for use with a BCI. In contrast, the system presented in this paper does not consist of one dedicated application, but enables the user to control mouse cursor and keyboard input on the level of the operating system, thereby making it possible to use arbitrary applications. As the c-VEP BCI method was shown to enable very fast communication speeds (writing more than 20 error-free characters per minute), the presented system is the next step in replacing the traditional mouse and keyboard and enabling complete brain-based control of a computer.

Acoustic Sensors for Air and Surface Navigation Applications

PubMed Central

Kapoor, Rohan; Ramasamy, Subramanian; Schyndel, Ron Van

2018-01-01

This paper presents the state-of-the-art and reviews the state-of-research of acoustic sensors used for a variety of navigation and guidance applications on air and surface vehicles. In particular, this paper focuses on echolocation, which is widely utilized in nature by certain mammals (e.g., cetaceans and bats). Although acoustic sensors have been extensively adopted in various engineering applications, their use in navigation and guidance systems is yet to be fully exploited. This technology has clear potential for applications in air and surface navigation/guidance for intelligent transport systems (ITS), especially considering air and surface operations indoors and in other environments where satellite positioning is not available. Propagation of sound in the atmosphere is discussed in detail, with all potential attenuation sources taken into account. The errors introduced in echolocation measurements due to Doppler, multipath and atmospheric effects are discussed, and an uncertainty analysis method is presented for ranging error budget prediction in acoustic navigation applications. Considering the design challenges associated with monostatic and multi-static sensor implementations and looking at the performance predictions for different possible configurations, acoustic sensors show clear promises in navigation, proximity sensing, as well as obstacle detection and tracking. The integration of acoustic sensors in multi-sensor navigation systems is also considered towards the end of the paper and a low Size, Weight and Power, and Cost (SWaP-C) sensor integration architecture is presented for possible introduction in air and surface navigation systems. PMID:29414894

Electric Potential and Electric Field Imaging with Dynamic Applications & Extensions

NASA Technical Reports Server (NTRS)

Generazio, Ed

2017-01-01

The technology and methods for remote quantitative imaging of electrostatic potentials and electrostatic fields in and around objects and in free space is presented. Electric field imaging (EFI) technology may be applied to characterize intrinsic or existing electric potentials and electric fields, or an externally generated electrostatic field made be used for volumes to be inspected with EFI. The baseline sensor technology (e-Sensor) and its construction, optional electric field generation (quasi-static generator), and current e- Sensor enhancements (ephemeral e-Sensor) are discussed. Critical design elements of current linear and real-time two-dimensional (2D) measurement systems are highlighted, and the development of a three dimensional (3D) EFI system is presented. Demonstrations for structural, electronic, human, and memory applications are shown. Recent work demonstrates that phonons may be used to create and annihilate electric dipoles within structures. Phonon induced dipoles are ephemeral and their polarization, strength, and location may be quantitatively characterized by EFI providing a new subsurface Phonon-EFI imaging technology. Results from real-time imaging of combustion and ion flow, and their measurement complications, will be discussed. Extensions to environment, Space and subterranean applications will be presented, and initial results for quantitative characterizing material properties are shown. A wearable EFI system has been developed by using fundamental EFI concepts. These new EFI capabilities are demonstrated to characterize electric charge distribution creating a new field of study embracing areas of interest including electrostatic discharge (ESD) mitigation, manufacturing quality control, crime scene forensics, design and materials selection for advanced sensors, combustion science, on-orbit space potential, container inspection, remote characterization of electronic circuits and level of activation, dielectric morphology of structures, tether integrity, organic molecular memory, atmospheric science, weather prediction, earth quake prediction, and medical diagnostic and treatment efficacy applications such as cardiac polarization wave propagation and electromyography imaging.

Using PHP/MySQL to Manage Potential Mass Impacts

NASA Technical Reports Server (NTRS)

Hager, Benjamin I.

2010-01-01

This paper presents a new application using commercially available software to manage mass properties for spaceflight vehicles. PHP/MySQL(PHP: Hypertext Preprocessor and My Structured Query Language) are a web scripting language and a database language commonly used in concert with each other. They open up new opportunities to develop cutting edge mass properties tools, and in particular, tools for the management of potential mass impacts (threats and opportunities). The paper begins by providing an overview of the functions and capabilities of PHP/MySQL. The focus of this paper is on how PHP/MySQL are being used to develop an advanced "web accessible" database system for identifying and managing mass impacts on NASA's Ares I Upper Stage program, managed by the Marshall Space Flight Center. To fully describe this application, examples of the data, search functions, and views are provided to promote, not only the function, but the security, ease of use, simplicity, and eye-appeal of this new application. This paper concludes with an overview of the other potential mass properties applications and tools that could be developed using PHP/MySQL. The premise behind this paper is that PHP/MySQL are software tools that are easy to use and readily available for the development of cutting edge mass properties applications. These tools are capable of providing "real-time" searching and status of an active database, automated report generation, and other capabilities to streamline and enhance mass properties management application. By using PHP/MySQL, proven existing methods for managing mass properties can be adapted to present-day information technology to accelerate mass properties data gathering, analysis, and reporting, allowing mass property management to keep pace with today's fast-pace design and development processes.

Project JOVE. [microgravity experiments and applications

NASA Technical Reports Server (NTRS)

Lyell, M. J.

1994-01-01

The goal of this project is to investigate new areas of research pertaining to free surface-interface fluids mechanics and/or microgravity which have potential commercial applications. This paper presents an introduction to ferrohydrodynamics (FHD), and discusses some applications. Also, computational methods for solving free surface flow problems are presented in detail. Both have diverse applications in industry and in microgravity fluids applications. Three different modeling schemes for FHD flows are addressed and the governing equations, including Maxwell's equations, are introduced. In the area of computational modeling of free surface flows, both Eulerian and Lagrangian schemes are discussed. The state of the art in computational methods applied to free surface flows is elucidated. In particular, adaptive grids and re-zoning methods are discussed. Additional research results are addressed and copies of the publications produced under the JOVE Project are included.

A categorical, improper probability method for combining NDVI and LiDAR elevation information for potential cotton precision agricultural applications

USDA-ARS?s Scientific Manuscript database

An algorithm is presented to fuse the Normalized Difference Vegetation Index (NDVI) with Light Detection and Ranging (LiDAR) elevation data to produce a map potentially useful for the site-specific scouting and pest management of several insect pests. In cotton, these pests include the Tarnished Pl...

Preparation and Application of Electrodes in Capacitive Deionization (CDI): a State-of-Art Review.

PubMed

Jia, Baoping; Zhang, Wei

2016-12-01

As a promising desalination technology, capacitive deionization (CDI) have shown practicality and cost-effectiveness in brackish water treatment. Developing more efficient electrode materials is the key to improving salt removal performance. This work reviewed current progress on electrode fabrication in application of CDI. Fundamental principal (e.g. EDL theory and adsorption isotherms) and process factors (e.g. pore distribution, potential, salt type and concentration) of CDI performance were presented first. It was then followed by in-depth discussion and comparison on properties and fabrication technique of different electrodes, including carbon aerogel, activated carbon, carbon nanotubes, graphene and ordered mesoporous carbon. Finally, polyaniline as conductive polymer and its potential application as CDI electrode-enhancing materials were also discussed.

Potential Applications of Polyamines in Agriculture and Plant Biotechnology.

PubMed

Tiburcio, Antonio F; Alcázar, Rubén

2018-01-01

The polyamines putrescine, spermidine and spermine have been implicated in a myriad of biological functions in many organisms. Research done during the last decades has accumulated a large body of evidence demonstrating that polyamines are key modulators of plant growth and development. Different experimental approaches have been employed including the measurement of endogenous polyamine levels and the activities of polyamine metabolic enzymes, the study of the effects resulting from exogenous polyamine applications and chemical or genetic manipulation of endogenous polyamine titers. This chapter reviews the role of PAs in seed germination, root development, plant architecture, in vitro plant regeneration, flowering and plant senescence. Evidence presented here indicates that polyamines should be regarded as plant growth regulators with potential applications in agriculture and plant biotechnology.

The present and future of nanotechnology in human health care.

PubMed

Sahoo, S K; Parveen, S; Panda, J J

2007-03-01

Nanotechnology is a multidisciplinary field that covers a vast and diverse array of devices derived from engineering, physics, chemistry, and biology. The burgeoning new field of nanotechnology, opened up by rapid advances in science and technology, creates myriad new opportunities for advancing medical science and disease treatment in human health care. Applications of nanotechnology to medicine and physiology imply materials and devices designed to interact with the body at subcellular (i.e., molecular) scales with a high degree of specificity. This can be potentially translated into targeted cellular and tissue-specific clinical applications designed to achieve maximal therapeutic efficacy with minimal side effects. In this review the chief scientific and technical aspects of nanotechnology are introduced, and some of its potential clinical applications are discussed.

Proposed application of lower body negative pressure to cardiology

NASA Technical Reports Server (NTRS)

Schmidt, E. V.; Debusk, R. F.; Popp, R. L.

1975-01-01

Potential medical applications are presented of lower body negative pressure to the evaluation and treatment of cardiac patients. The essential features of an LBNP unit and the basic cardiovascular physiology of lower body negative pressure (LBNP) testing are described. Some of the results of previous spaceflight experiences and bedrest studies are summarized. The deconditioning effects of weightlessness experienced by orbiting astronauts are compared with the effects of bedrest restrictions prescribed for convalescing cardiac patients. The potential of LBNP for evaluating both pharmacological and physical activity regimens was examined, particularly in relation to post-myocardial infarction and coronary artery bypass patients. Applications of LBNP to the cardiac catheterization laboratory and the out-patient follow-up of cardiac patients are proposed.

Human osteopontin splicing isoforms: known roles, potential clinical applications and activated signaling pathways.

PubMed

Gimba, E R; Tilli, T M

2013-04-30

Human osteopontin is subject to alternative splicing, which generates three isoforms, termed OPNa, OPNb and OPNc. These variants show specific expression and roles in different cell contexts. We present an overview of current knowledge of the expression profile of human OPN splicing isoforms (OPN-SIs), their tissue-specific roles, and the pathways mediating their functional properties in different pathophysiological conditions. We also describe their putative application as biomarkers, and their potential use as therapeutic targets by using antibodies, oligonucleotides or siRNA molecules. This synthesis provides new clues for a better understanding of human OPN splice variants, their roles in normal and pathological conditions, and their possible clinical applications. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Linear Augmentation for Stabilizing Stationary Solutions: Potential Pitfalls and Their Application

PubMed Central

Karnatak, Rajat

2015-01-01

Linear augmentation has recently been shown to be effective in targeting desired stationary solutions, suppressing bistablity, in regulating the dynamics of drive response systems and in controlling the dynamics of hidden attractors. The simplicity of the procedure is the main highlight of this scheme but questions related to its general applicability still need to be addressed. Focusing on the issue of targeting stationary solutions, this work demonstrates instances where the scheme fails to stabilize the required solutions and leads to other complicated dynamical scenarios. Examples from conservative as well as dissipative systems are presented in this regard and important applications in dissipative predator—prey systems are discussed, which include preventative measures to avoid potentially catastrophic dynamical transitions in these systems. PMID:26544879

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hendon, Christopher H.; Rieth, Adam J.; Korzyński, Maciej D.

Metal–organic frameworks (MOFs) allow compositional and structural diversity beyond conventional solid-state materials. Continued interest in the field is justified by potential applications of exceptional breadth, ranging from gas storage and separation, which takes advantage of the inherent pores and their volume, to electronic applications, which requires precise control of electronic structure. In this Outlook we present some of the pertinent challenges that MOFs face in their conventional implementations, as well as opportunities in less traditional areas. Here the aim is to discuss select design concepts and future research goals that emphasize nuances relevant to this class of materials as amore » whole. Particular emphasis is placed on synthetic aspects, as they influence the potential for MOFs in gas separation, electrical conductivity, and catalytic applications.« less

GEM detectors for WEST and potential application for heavy impurity transport studies

NASA Astrophysics Data System (ADS)

Mazon, D.; Jardin, A.; Coston, C.; Faisse, F.; Chernyshova, M.; Czarski, T.; Kasprowicz, G.; Wojenski, A.

2016-08-01

In tokamaks equipped with metallic walls and in particular tungsten, the interplay between particle transport and MagnetoHydroDynamic (MHD) activity might lead to impurities accumulation and finally to sudden plasma termination called disruption. Studying such transport phenomena is thus essential if stationary discharges are to be achieved. On WEST a new SXR diagnostic is developed in collaboration with IPPLM (Poland) and the Warsaw University of Technology, based on a triple Gas Electron Multiplier (GEM) detector. Potential application of the WEST GEM detectors for tomographic reconstruction and subsequent transport analysis is presented.

[Ecological memory and its potential applications in ecology: a review].

PubMed

Sun, Zhong-yu; Ren, Hai

2011-03-01

Ecological memory (EM) is defined as the capability of the past states or experiences of a community to influence the present or future ecological responses of the community. As a relatively new concept, EM has received considerable attention in the study of ecosystem structure and function, such as community succession, ecological restoration, biological invasion, and natural resource management. This review summarized the definition, components, and categories of EM, and discussed the possible mechanisms and affecting factors of EM. Also, the potential applications of EM were proposed, in order to further understand the mechanisms of community succession and to guide ecological restoration.

BEM for wave equation with boundary in arbitrary motion and applications to compressible potential aerodynamics of airplanes and helicopters

NASA Technical Reports Server (NTRS)

Morino, Luigi; Bharadvaj, Bala K.; Freedman, Marvin I.; Tseng, Kadin

1988-01-01

The wave equation for an object in arbitrary motion is investigated analytically using a BEM approach, and practical applications to potential flows of compressible fluids around aircraft wings and helicopter rotors are considered. The treatment accounts for arbitrary combined rotational and translational motion of the reference frame and for the wake motion. The numerical implementation as a computer algorithm is demonstrated on problems with prescribed and free wakes, the former in compressible flows and the latter for incompressible flows; results are presented graphically and briefly characterized.

Evaluation of heat engine for hybrid vehicle application

NASA Technical Reports Server (NTRS)

Schneider, H. W.

1984-01-01

The status of ongoing heat-engine developments, including spark-ignition, compression-ignition, internal-combustion, and external-combustion engines is presented. The potential of engine concepts under consideration for hybrid vehicle use is evaluated, using self-imposed criteria for selection. The deficiencies of the engines currently being evaluated in hybrid vehicles are discussed. Focus is on recent research with two-stroke, rotary, and free-piston engines. It is concluded that these engine concepts have the most promising potential for future application in hybrid vehicles. Recommendations are made for analysis and experimentation to evaluate stop-start and transient emission behavior of recommended engine concepts.

Shape memory alloys: Properties and biomedical applications

NASA Astrophysics Data System (ADS)

Mantovani, Diego

2000-10-01

Shape memory alloys provide new insights for the design of biomaterials in bioengineering for the design of artificial organs and advanced surgical instruments, since they have specific characteristics and unusual properties. This article will examine (a) the four properties of shape memory alloys, (b) medical applications with high potential for improving the present and future quality of life, and (c) concerns regarding the biocom-patibility properties of nickel-titanium alloys. In particular, the long-term challenges of using shape memory alloys will be discussed, regarding corrosion and potential leakage of elements and ions that could be toxic to cells, tissues and organs.

Bacterial Magnetosome: A Novel Biogenetic Magnetic Targeted Drug Carrier with Potential Multifunctions

PubMed Central

Sun, Jianbo; Li, Ying; Liang, Xing-Jie; Wang, Paul C.

2012-01-01

Bacterial magnetosomes (BMs) synthesized by magnetotactic bacteria have recently drawn great interest due to their unique features. BMs are used experimentally as carriers for antibodies, enzymes, ligands, nucleic acids, and chemotherapeutic drugs. In addition to the common attractive properties of magnetic carriers, BMs also show superiority as targeting nanoscale drug carriers, which is hardly matched by artificial magnetic particles. We are presenting the potential applications of BMs as drug carriers by introducing the drug-loading methods and strategies and the recent research progress of BMs which has contributed to the application of BMs as drug carriers. PMID:22448162

Application of advanced coating techniques to rocket engine components

NASA Technical Reports Server (NTRS)

Verma, S. K.

1988-01-01

The materials problem in the space shuttle main engine (SSME) is reviewed. Potential coatings and the method of their application for improved life of SSME components are discussed. A number of advanced coatings for turbine blade components and disks are being developed and tested in a multispecimen thermal fatigue fluidized bed facility at IIT Research Institute. This facility is capable of producing severe strains of the degree present in blades and disk components of the SSME. The potential coating systems and current efforts at IITRI being taken for life extension of the SSME components are summarized.

Effects of herbicide applications in wheat fields

PubMed Central

Varshney, Sugandha; Hayat, Shamshul; Alyemeni, Mohammed Nasser; Ahmad, Aqil

2012-01-01

The present review encompasses the physiological and yield constraints of herbicide applications with special reference to wheat productivity. Post-independence lagging of Indian agriculture to feed its population led to haphazard use of chemical pesticides and weedicides which deteriorated the productivity pay-off particularly of wheat and rice. Past some decades witnessed the potential use of certain phytohormones in augmenting abiotic stress to get rid of yield gap and productivity constraints. We summed up with reviewing the potential role of these natural regulators in overcoming above mentioned drawbacks to substitute or to integrate these chemicals with the use of plant hormones. PMID:22516826

Data base management study

NASA Technical Reports Server (NTRS)

1976-01-01

Data base management techniques and applicable equipment are described. Recommendations which will assist potential NASA data users in selecting and using appropriate data base management tools and techniques are presented. Classes of currently available data processing equipment ranging from basic terminals to large minicomputer systems were surveyed as they apply to the needs of potential SEASAT data users. Cost and capabilities projections for this equipment through 1985 were presented. A test of a typical data base management system was described, as well as the results of this test and recommendations to assist potential users in determining when such a system is appropriate for their needs. The representative system tested was UNIVAC's DMS 1100.

Present and future medical applications of microbial exopolysaccharides

PubMed Central

Moscovici, Misu

2015-01-01

Microbial exopolysaccharides (EPS) have found outstanding medical applications since the mid-20th century, with the first clinical trials on dextran solutions as plasma expanders. Other EPS entered medicine firstly as conventional pharmaceutical excipients (e.g., xanthan – as suspension stabilizer, or pullulan – in capsules and oral care products). Polysaccharides, initially obtained from plant or animal sources, became easily available for a wide range of applications, especially when they were commercially produced by microbial fermentation. Alginates are used as anti-reflux, dental impressions, or as matrix for tablets. Hyaluronic acid and derivatives are used in surgery, arthritis treatment, or wound healing. Bacterial cellulose is applied in wound dressings or scaffolds for tissue engineering. The development of drug controlled-release systems and of micro- and nanoparticulated ones, has opened a new era of medical applications for biopolymers. EPS and their derivatives are well-suited potentially non-toxic, biodegradable drug carriers. Such systems concern rating and targeting of controlled release. Their large area of applications is explained by the available manifold series of derivatives, whose useful properties can be thereby controlled. From matrix inclusion to conjugates, different systems have been designed to solubilize, and to assure stable transport in the body, target accumulation and variable rate-release of a drug substance. From controlled drug delivery, EPS potential applications expanded to vaccine adjuvants and diagnostic imaging systems. Other potential applications are related to the bioactive (immunomodulator, antitumor, antiviral) characteristics of EPS. The numerous potential applications still wait to be developed into commercial pharmaceuticals and medical devices. Based on previous and recent results in important medical-pharmaceutical domains, one can undoubtedly state that EPS medical applications have a broad future ahead. PMID:26483763

Market assessment of photovoltaic power systems for agricultural applications in Nigeria

NASA Technical Reports Server (NTRS)

Staples, D.; Steingass, H.; Nolfi, J.

1981-01-01

The market potential for stand-alone photovoltaic systems in agriculture was studied. Information is presented on technical and economically feasible applications, and assessments of the business, government and financial climate for photovoltaic sales. It is concluded that the market for stand-alone systems will be large because of the availability of captial and the high premium placed on high reliability, low maintenance power systems. Various specific applications are described, mostly related to agriculture.

Electronic neuroprocessors

NASA Technical Reports Server (NTRS)

Thakoor, Anil

1991-01-01

The JPL Center for Space Microelectronics Technology (CSMT) is actively pursuing research in the neural network theory, algorithms, and electronics as well as optoelectronic neural net hardware implementations, to explore the strengths and application potential for a variety of NASA, DoD, as well as commercial application problems, where conventional computing techniques are extremely time-consuming, cumbersome, or simply non-existent. An overview of the JPL electronic neural network hardware development activities and some of the striking applications of the JPL electronic neuroprocessors are presented.

Market assessment of photovoltaic power systems for agricultural applications in Nigeria

NASA Astrophysics Data System (ADS)

Staples, D.; Steingass, H.; Nolfi, J.

1981-10-01

The market potential for stand-alone photovoltaic systems in agriculture was studied. Information is presented on technical and economically feasible applications, and assessments of the business, government and financial climate for photovoltaic sales. It is concluded that the market for stand-alone systems will be large because of the availability of captial and the high premium placed on high reliability, low maintenance power systems. Various specific applications are described, mostly related to agriculture.

[The present study situation and application prospect of nail analysis for abused drugs].

PubMed

Chen, Hang; Xiang, Ping; Shen, Min

2010-10-01

In forensic toxicology analysis, various types of biological samples have their own special characteristics and scope of applications. In this article, the physiological structure of nails, methods for collecting and pre-processing samples, and for analyzing some poisons and drugs in the nails are reviewed with details. This paper introduces the influence factors of drug abuse of the nails. The prospects of its further applications are concluded based on the research results. Nails, as an unconventional bio-sample without general application, show great potential and advantages in forensic toxicology.

Boron Nitride Nanotubes: Recent Advances in Their Synthesis, Functionalization, and Applications.

PubMed

Lee, Chee Huei; Bhandari, Shiva; Tiwari, Bishnu; Yapici, Nazmiye; Zhang, Dongyan; Yap, Yoke Khin

2016-07-15

A comprehensive overview of current research progress on boron nitride nanotubes (BNNTs) is presented in this article. Particularly, recent advancements in controlled synthesis and large-scale production of BNNTs will first be summarized. While recent success in mass production of BNNTs has opened up new opportunities to implement the appealing properties in various applications, concerns about product purity and quality still remain. Secondly, we will summarize the progress in functionalization of BNNTs, which is the necessary step for their applications. Additionally, selected potential applications in structural composites and biomedicine will be highlighted.

Applications and requirements for real-time simulators in ground-test facilities

NASA Technical Reports Server (NTRS)

Arpasi, Dale J.; Blech, Richard A.

1986-01-01

This report relates simulator functions and capabilities to the operation of ground test facilities, in general. The potential benefits of having a simulator are described to aid in the selection of desired applications for a specific facility. Configuration options for integrating a simulator into the facility control system are discussed, and a logical approach to configuration selection based on desired applications is presented. The functional and data path requirements to support selected applications and configurations are defined. Finally, practical considerations for implementation (i.e., available hardware and costs) are discussed.

Biological Activities and Potential Oral Applications of N-Acetylcysteine: Progress and Prospects

PubMed Central

Pei, Yanping; Liu, Huan; Yang, Yi; Yang, Yanwei

2018-01-01

N-Acetylcysteine (NAC), a cysteine prodrug and glutathione (GSH) precursor, has been used for several decades in clinical therapeutic practices as a mucolytic agent and for the treatment of disorders associated with GSH deficiency. Other therapeutic activities of NAC include inhibition of inflammation/NF-κB signaling and expression of proinflammatory cytokines. N-Acetylcysteine is also a nonantibiotic compound possessing antimicrobial property and exerts anticarcinogenic and antimutagenic effects against certain types of cancer. Recently, studies describing potentially important biological and pharmacological activities of NAC have stimulated interests in using NAC-based therapeutics for oral health care. The present review focused on the biological activities of NAC and its potential oral applications. The potential side effects of NAC and formulations for drug delivery were also discussed, with the intent of advancing NAC-associated treatment modalities in oral medicine. PMID:29849877

Knowledge mapping as a technique to support knowledge translation.

PubMed Central

Ebener, S.; Khan, A.; Shademani, R.; Compernolle, L.; Beltran, M.; Lansang, Ma; Lippman, M.

2006-01-01

This paper explores the possibility of integrating knowledge mapping into a conceptual framework that could serve as a tool for understanding the many complex processes, resources and people involved in a health system, and for identifying potential gaps within knowledge translation processes in order to address them. After defining knowledge mapping, this paper presents various examples of the application of this process in health, before looking at the steps that need to be taken to identify potential gaps, to determine to what extent these gaps affect the knowledge translation process and to establish their cause. This is followed by proposals for interventions aimed at strengthening the overall process. Finally, potential limitations on the application of this framework at the country level are addressed. PMID:16917651

Mineral resource of the month: graphite

USGS Publications Warehouse

,

2008-01-01

The article presents facts about graphite ideal for industrial applications. Among the characteristics of graphite are its metallic luster, softness, perfect basal cleavage and electrical conductivity. Batteries, brake linings and powdered metals are some of the products that make use of graphite. It attributes the potential applications for graphite in high-technology fields to innovations in thermal technology and acid-leaching techniques.

Field-structured material media and methods for synthesis thereof

DOEpatents

Martin, James E.; Hughes, Robert C.; Anderson, Robert A.

2001-09-18

The present application is directed to a new class of composite materials, called field-structured composite (FSC) materials, which comprise a oriented aggregate structure made of magnetic particles suspended in a nonmagnetic medium, and to a new class of processes for their manufacture. FSC materials have much potential for application, including use in chemical, optical, environmental, and mechanical sensors.

Melnikov method approach to control of homoclinic/heteroclinic chaos by weak harmonic excitations.

PubMed

Chacón, Ricardo

2006-09-15

A review on the application of Melnikov's method to control homoclinic and heteroclinic chaos in low-dimensional, non-autonomous and dissipative oscillator systems by weak harmonic excitations is presented, including diverse applications, such as chaotic escape from a potential well, chaotic solitons in Frenkel-Kontorova chains and chaotic-charged particles in the field of an electrostatic wave packet.

MP3 Players: Applications and Implications for the Use of Popular Technology in Secondary Schools

ERIC Educational Resources Information Center

Stiler, Gary M.

2007-01-01

This article explores potential uses for MP3 players in secondary classrooms. It presents an overview of current applications and describes an exploratory study of classroom uses. Seven high school teachers and one teacher educator participated in a three-month project to examine MP3 technology as applied to high school instruction. Their ideas…

Application of an Integrated Methodology for Propulsion and Airframe Control Design to a STOVL Aircraft

NASA Technical Reports Server (NTRS)

Garg, Sanjay; Mattern, Duane

1994-01-01

An advanced methodology for integrated flight propulsion control (IFPC) design for future aircraft, which will use propulsion system generated forces and moments for enhanced maneuver capabilities, is briefly described. This methodology has the potential to address in a systematic manner the coupling between the airframe and the propulsion subsystems typical of such enhanced maneuverability aircraft. Application of the methodology to a short take-off vertical landing (STOVL) aircraft in the landing approach to hover transition flight phase is presented with brief description of the various steps in the IFPC design methodology. The details of the individual steps have been described in previous publications and the objective of this paper is to focus on how the components of the control system designed at each step integrate into the overall IFPC system. The full nonlinear IFPC system was evaluated extensively in nonreal-time simulations as well as piloted simulations. Results from the nonreal-time evaluations are presented in this paper. Lessons learned from this application study are summarized in terms of areas of potential improvements in the STOVL IFPC design as well as identification of technology development areas to enhance the applicability of the proposed design methodology.

Practical applications of space systems. [environmental quality and resources management

NASA Technical Reports Server (NTRS)

1975-01-01

The study was conducted to provide an opportunity for knowledgeable users to express their needs for information or services which might or might not be met by space systems, and to relate the present and potential capabilities of space systems to their needs. The needs, accomplishments to date, and future possibilities in the applications of space systems for providing food and energy, while at the same time improving and safeguarding the physical environment and the quality of life, are presented. Organizing the usage of these space systems capabilities is also discussed.

NASA GSFC Strategic Nanotechnology Interests: Symposium on High-Rate Nanoscale Printing for Devices and Structures

NASA Technical Reports Server (NTRS)

Ericsson, Aprille J.

2014-01-01

The seminars invitees include representatives from industry, nonprofit research facility and universities. The presentation provides an overview of the NASAGSFC locations, technical capabilities and applied nanotechnology interests. Initially presented are advances by the broader technological communities on current miniaturized multiscale advanced manufacturing and 3D printing products on the micro and macro scale. Briefly assessed is the potential of moving toward the nanoscale for possible space flight applications and challenges. Lastly, highlighted are GSFCs current successes in nano-technology developments and targeted future applications.

Ab initio simulations of scanning-tunneling-microscope images with embedding techniques and application to C58-dimers on Au(111).

PubMed

Wilhelm, Jan; Walz, Michael; Stendel, Melanie; Bagrets, Alexei; Evers, Ferdinand

2013-05-14

We present a modification of the standard electron transport methodology based on the (non-equilibrium) Green's function formalism to efficiently simulate STM-images. The novel feature of this method is that it employs an effective embedding technique that allows us to extrapolate properties of metal substrates with adsorbed molecules from quantum-chemical cluster calculations. To illustrate the potential of this approach, we present an application to STM-images of C58-dimers immobilized on Au(111)-surfaces that is motivated by recent experiments.

The interaction of MnH(X 7Σ+) with He: Ab initio potential energy surface and bound states

NASA Astrophysics Data System (ADS)

Turpin, Florence; Halvick, Philippe; Stoecklin, Thierry

2010-06-01

The potential energy surface of the ground state of the He-MnH(X Σ7+) van der Waals complex is presented. Within the supermolecular approach of intermolecular energy calculations, a grid of ab initio points was computed at the multireference configuration interaction level using the aug-cc-pVQZ basis set for helium and hydrogen and the relativistic aug-cc-pVQZ-DK basis set for manganese. The potential energy surface was then fitted to a global analytical form which main features are discussed. As a first application of this potential energy surface, we present accurate calculations of bound energy levels of the H3e-MnH and H4e-MnH complexes.

The interaction of MnH(X 7Sigma+) with He: ab initio potential energy surface and bound states.

PubMed

Turpin, Florence; Halvick, Philippe; Stoecklin, Thierry

2010-06-07

The potential energy surface of the ground state of the He-MnH(X (7)Sigma(+)) van der Waals complex is presented. Within the supermolecular approach of intermolecular energy calculations, a grid of ab initio points was computed at the multireference configuration interaction level using the aug-cc-pVQZ basis set for helium and hydrogen and the relativistic aug-cc-pVQZ-DK basis set for manganese. The potential energy surface was then fitted to a global analytical form which main features are discussed. As a first application of this potential energy surface, we present accurate calculations of bound energy levels of the (3)He-MnH and (4)He-MnH complexes.

Wireless Sensor Applications in Extreme Aeronautical Environments

NASA Technical Reports Server (NTRS)

Wilson, William C.; Atkinson, Gary M.

2013-01-01

NASA aeronautical programs require rigorous ground and flight testing. Many of the testing environments can be extremely harsh. These environments include cryogenic temperatures and high temperatures (greater than 1500 C). Temperature, pressure, vibration, ionizing radiation, and chemical exposure may all be part of the harsh environment found in testing. This paper presents a survey of research opportunities for universities and industry to develop new wireless sensors that address anticipated structural health monitoring (SHM) and testing needs for aeronautical vehicles. Potential applications of passive wireless sensors for ground testing and high altitude aircraft operations are presented. Some of the challenges and issues of the technology are also presented.

Life-cycle costing: Practical considerations

NASA Technical Reports Server (NTRS)

Eisenberger, I.; Lorden, G.

1977-01-01

The history and methodology of life-cycle costing are presented and analyzed, contrasting the potential benefits of the technique with the difficulties of its application. Examples and a short survey of the literature are given.

Superchilling of muscle foods: Potential alternative for chilling and freezing.

PubMed

Banerjee, Rituparna; Maheswarappa, Naveena Basappa

2017-12-05

Superchilling is an attractive technique for preservation of muscle foods which freezes part of the water and insulate the food products from temperature fluctuations thereby enhancing the shelf-life during storage, transportation and retailing. Superchilling process synergistically improves the product shelf-life when used in combination with vacuum or modified atmospheric packaging. The shelf-life of muscle foods was reported to be increased by 1.5 to 4.0 times relative to traditional chilling technique. Advantages of superchilling and its ability to maintain the freshness of muscle foods over freezing has been discussed and its potential for Industrial application is highlighted. Present review also unravel the mechanistic bases for ice-crystal formation during superchilling and measures to ameliorate the drip loss. The future challenges especially automation in superchilling process for large scale Industrial application is presented.

Microhydraulic transducer technology for actuation and power generation

NASA Astrophysics Data System (ADS)

Hagood, Nesbitt W.; Roberts, David C.; Saggere, Laxminarayana; Breuer, Kenneth S.; Chen, Kuo-Shen; Carretero, Jorge A.; Li, Hanqing; Mlcak, Richard; Pulitzer, Seward W.; Schmidt, Martin A.; Spearing, S. Mark; Su, Yu-Hsuan

2000-06-01

The paper introduces a novel transducer technology, called the solid-state micro-hydraulic transducer, currently under development at MIT. The new technology is enabled through integration of micromachining technology, piezoelectrics, and microhydraulic concepts. These micro-hydraulic transducers are capable of bi-directional electromechanical energy conversion, i.e., they can operate as both an actuator that supplies high mechanical force in response to electrical input and an energy generator that transduces electrical energy from mechanical energy in the environment. These transducers are capable of transducing energy at very high specific power output in the order of 1 kW/kg, and thus, they have the potential to enable many novel applications. The concept, the design, and the potential applications of the transducers are presented. Present efforts towards the development of these transducers, and the challenges involved therein, are also discussed.

Study of orifice fabrication technologies for the liquid droplet radiator

NASA Technical Reports Server (NTRS)

Wallace, David B.; Hayes, Donald J.; Bush, J. Michael

1991-01-01

Eleven orifice fabrication technologies potentially applicable for a liquid droplet radiator are discussed. The evaluation is focused on technologies capable of yielding 25-150 microns diameter orifices with trajectory accuracies below 5 milliradians, ultimately in arrays of up to 4000 orifices. An initial analytical screening considering factors such as trajectory accuracy, manufacturability, and hydrodynamics of orifice flow is presented. Based on this screening, four technologies were selected for experimental evaluation. A jet straightness system used to test 50-orifice arrays made by electro-discharge machining (EDM), Fotoceram, and mechanical drilling is discussed. Measurements on orifice diameter control and jet trajectory accuracy are presented and discussed. Trajectory standard deviations are in the 4.6-10.0 milliradian range. Electroforming and EDM appear to have the greatest potential for Liquid Droplet Radiator applications. The direction of a future development effort is discussed.

Fuel Cell Activities at the NASA Glenn Research Center

NASA Technical Reports Server (NTRS)

Kohout, Lisa L.; Lyons, Valerie (Technical Monitor)

2002-01-01

Fuel cells have a long history in space applications and may have potential application in aeronautics as well. A fuel cell is an electrochemical energy conversion device that directly transforms the chemical energy of a fuel and oxidant into electrical energy. Alkaline fuel cells have been the mainstay of the U.S. space program, providing power for the Apollo missions and the Space Shuttle. However, Proton Exchange Membrane (PEM) fuel cells offer potential benefits over alkaline systems and are currently under development for the next generation Reusable Launch Vehicle (RLV). Furthermore, primary and regenerative systems utilizing PEM technology are also being considered for future space applications such as surface power and planetary aircraft. In addition to these applications, the NASA Glenn Research Center is currently studying the feasibility of the use of both PEM and solid oxide fuel cells for low- or zero-emission electric aircraft propulsion. These types of systems have potential applications for high altitude environmental aircraft, general aviation and commercial aircraft, and high attitude airships. NASA Glenn has a unique set of capabilities and expertise essential to the successful development of advanced fuel cell power systems for space and aeronautics applications. NASA Glenn's role in past fuel cell development programs as well as current activities to meet these new challenges will be presented

Legume Lectins: Proteins with Diverse Applications

PubMed Central

Lagarda-Diaz, Irlanda; Guzman-Partida, Ana Maria; Vazquez-Moreno, Luz

2017-01-01

Lectins are a diverse class of proteins distributed extensively in nature. Among these proteins; legume lectins display a variety of interesting features including antimicrobial; insecticidal and antitumor activities. Because lectins recognize and bind to specific glycoconjugates present on the surface of cells and intracellular structures; they can serve as potential target molecules for developing practical applications in the fields of food; agriculture; health and pharmaceutical research. This review presents the current knowledge of the main structural characteristics of legume lectins and the relationship of structure to the exhibited specificities; provides an overview of their particular antimicrobial; insecticidal and antitumor biological activities and describes possible applications based on the pattern of recognized glyco-targets. PMID:28604616

NASA contributions to fluidic systems: A survey

NASA Technical Reports Server (NTRS)

Weathers, T. M.

1972-01-01

A state-of-the art review of fluidic technology is presented. It is oriented towards systems applications rather than theory or design. It draws heavily upon work performed or sponsored by NASA in support of the space program and aeronautical research and development (R&D). Applications are emphasized in this survey because it is hoped that the examples described and the criteria presented for evaluating the suitability of fluidics to new applications will be of value to potential users of fluidic systems. This survey of the fluidics industry suggests some of the means whereby a company may use a fluidic system effectively either to manufacture a product or as part of the end product.

Applications of diatoms as potential microalgae in nanobiotechnology.

PubMed

Jamali, Ali Akbar; Akbari, Fariba; Ghorakhlu, Mohamad Moradi; de la Guardia, Miguel; Yari Khosroushahi, Ahmad

2012-01-01

Diatoms are single cell eukaryotic microalgae, which present in nearly every water habitat make them ideal tools for a wide range of applications such as oil explora-tion, forensic examination, environmental indication, biosilica pattern generation, toxicity testing and eutrophication of aqueous ecosystems. Essential information on diatoms were reviewed and discussed towards impacts of diatoms on biosynthesis and bioremediation. In this review, we present the recent progress in this century on the application of diatoms in waste degradation, synthesis of biomaterial, biomineraliza-tion, toxicity and toxic effects of mineral elements evaluations. Diatoms can be considered as metal toxicity bioindicators and they can be applied for biomineralization, synthesis of biomaterials, and degradation of wastes.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farrell, John T; Kelly, Kenneth J; Duran, Adam W

Range-extended electric vehicle (EV) technology can be a viable option for reducing fuel consumption from medium-duty (MD) and heavy-duty (HD) engines by approximately 50 percent or more. Such engines have wide variations in use and duty cycles, however, and identifying the vocations/duty cycles most suitable for range-extended applications is vital for maximizing the potential benefits. This presentation provides information about NREL's research on range-extended EV technologies, with a focus on NREL's real-world data collection and analysis approach to identifying the vocations/duty cycles best suited for range-extender applications and to help guide related powertrain optimization and design requirements. The presentation alsomore » details NREL's drive cycle development process as it pertains to package delivery applications.« less

Application of fiber tapers in astronomy

NASA Astrophysics Data System (ADS)

Marcel, Jaclyn; Haynes, Roger; Bland-Hawthorn, Joss

2006-06-01

Fiber tapers have the potential to significantly advance instrument technology into the realm of fully integrated optical systems. Our initial investigation was directed at the use of fiber tapers as f-ratio transformation devices. Using a technique developed for testing focal ratio degradation (FRD), a collimated light source was injected at different angles into various fiber taper samples and the far-field profile of the fiber output was observed. We compare the FRD present in the optical fiber tapers with conventional fibers and determine how effectively fiber tapers perform as image converters. We demonstrate that while silica fiber tapers may have slightly more intrinsic FRD than conventional fibers they still show promise as adiabatic mode transformers and are worth investigating further for their potential use in astronomical instruments. In this paper we present a brief review of the current status of fiber tapers with particular focus on the astronomical applications. We demonstrate the conservation of etendue in the taper transformation process and present the experimental results for a number of different taper profiles and manufacturers.

Clinical Applications of Hallucinogens: A Review

PubMed Central

Garcia-Romeu, Albert; Kersgaard, Brennan; Addy, Peter H.

2016-01-01

Hallucinogens fall into several different classes, as broadly defined by pharmacological mechanism of action, and chemical structure. These include psychedelics, entactogens, dissociatives, and other atypical hallucinogens. Although these classes do not share a common primary mechanism of action, they do exhibit important similarities in their ability to occasion temporary but profound alterations of consciousness, involving acute changes in somatic, perceptual, cognitive, and affective processes. Such effects likely contribute to their recreational use. However, a growing body of evidence indicates that these drugs may have therapeutic applications beyond their potential for abuse. This review will present data on several classes of hallucinogens with a particular focus on psychedelics, entactogens, and dissociatives, for which clinical utility has been most extensively documented. Information on each class is presented in turn, tracing relevant historical insights, highlighting similarities and differences between the classes from the molecular to the behavioral level, and presenting the most up-to-date information on clinically oriented research with these substances, with important ramifications for their potential therapeutic value. PMID:27454674

Clinical grade adult stem cell banking

PubMed Central

Thirumala, Sreedhar; Goebel, W Scott

2009-01-01

There has been a great deal of scientific interest recently generated by the potential therapeutic applications of adult stem cells in human care but there are several challenges regarding quality and safety in clinical applications and a number of these challenges relate to the processing and banking of these cells ex-vivo. As the number of clinical trials and the variety of adult cells used in regenerative therapy increases, safety remains a primary concern. This has inspired many nations to formulate guidelines and standards for the quality of stem cell collection, processing, testing, banking, packaging and distribution. Clinically applicable cryopreservation and banking of adult stem cells offers unique opportunities to advance the potential uses and widespread implementation of these cells in clinical applications. Most current cryopreservation protocols include animal serum proteins and potentially toxic cryoprotectant additives (CPAs) that prevent direct use of these cells in human therapeutic applications. Long term cryopreservation of adult stem cells under good manufacturing conditions using animal product free solutions is critical to the widespread clinical implementation of ex-vivo adult stem cell therapies. Furthermore, to avoid any potential cryoprotectant related complications, reduced CPA concentrations and efficient post-thaw washing to remove CPA are also desirable. The present review focuses on the current strategies and important aspects of adult stem cell banking for clinical applications. These include current good manufacturing practices (cGMPs), animal protein free freezing solutions, cryoprotectants, freezing & thawing protocols, viability assays, packaging and distribution. The importance and benefits of banking clinical grade adult stem cells are also discussed. PMID:20046678

Surface and subsurface geologic risk factors to ground water affecting brownfield redevelopment potential.

PubMed

Kaufman, Martin M; Murray, Kent S; Rogers, Daniel T

2003-01-01

A model is created for assessing the redevelopment potential of brownfields. The model is derived from a space and time conceptual framework that identifies and measures the surface and subsurface risk factors present at brownfield sites. The model then combines these factors with a contamination extent multiplier at each site to create an index of redevelopment potential. Results from the application of the model within an urbanized watershed demonstrate clear differences between the redevelopment potential present within five different near-surface geologic units, with those units containing clay being less vulnerable to subsurface contamination. With and without the extent multiplier, the total risk present at the brownfield sites within all the geologic units is also strongly correlated to the actual costs of remediation. Thus, computing the total surface and subsurface risk within a watershed can help guide the remediation efforts at broad geographic scales, and prioritize the locations for redevelopment.

Inhibitory effects of multiwall carbon nanotubes with high iron impurity on viability and neuronal differentiation in cultured PC12 cells.

PubMed

Meng, Li; Jiang, Aihua; Chen, Rui; Li, Chen-zhong; Wang, Liming; Qu, Ying; Wang, Peng; Zhao, Yuliang; Chen, Chunying

2013-11-08

The increasing use of carbon nanotubes (CNTs) in biomedical applications has garnered a great concern on their potential negative effects to human health. CNTs have been reported to potentially disrupt normal neuronal function and they were speculated to accumulate and cause brain damage, although a lot of distinct and exceptional properties and potential wide applications have been associated with this material in neurobiology. Fe impurities strapped inside the CNTs may be partially responsible for neurotoxicity generation. In the present study, we selected rat pheochromocytoma (PC12) cells to investigate and compare the effects of two kinds of multiwall carbon nanotubes (MWCNTs) with different concentrations of Fe impurities which usually come from the massive production of CNTs by chemical vapor deposition. Exposure to Fe-high MWCNTs can reduce cell viability and increase cytoskeletal disruption of undifferentiated PC12 cells, diminish the ability to form mature neurites, and then adversely influence the neuronal dopaminergic phenotype in NGF-treated PC-12 cells. The present results highlight the critical role of iron residue in the adverse response to MWCNTs exposure in neural cells. These findings provide useful information for understanding the toxicity and safe application of carbon nanotubes. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Responses of Withdrawal Interneurons to Serotonin Applications in Naïve and Learned Snails Are Different

PubMed Central

Bogodvid, Tatiana K.; Andrianov, Vyatcheslav V.; Deryabina, Irina B.; Muranova, Lyudmila N.; Silantyeva, Dinara I.; Vinarskaya, Aliya; Balaban, Pavel M.; Gainutdinov, Khalil L.

2017-01-01

Long-term changes in membrane potential after associative training were described previously in identified premotor interneurons for withdrawal of the terrestrial snail Helix. Serotonin was shown to be a major transmitter involved in triggering the long-term changes in mollusks. In the present study we compared the changes in electrophysiological characteristics of identifiable premotor interneurons for withdrawal in response to bath applications of serotonin (5-HT) or serotonin precursor 5-hydroxytryptophan (5-HTP) in preparations from naïve, neurotoxin-injected or associatively trained snails. It was found that 5-HT or 5-HTP applications caused a significant decrease of membrane potential in premotor interneurons of naïve snails, associatively trained snails and snails with impaired serotonergic system by injection of a selective neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) 1 week before the experiments. Applications of 5-HT or 5-HTP did not cause significant changes in the action potential (AP) threshold potential of these neurons in naïve snails. Conversely, applications of 5-HT or 5-HTP to the premotor interneurons of previously trained or 5,7-DHT-injected snails caused a significant increase in the firing threshold potential in spite of a depolarizing shift of the resting membrane potential. Results demonstrate that responsiveness of premotor interneurons to extracellularly applied 5-HT or 5-HTP changes for days after the associative training or serotonin depletion. Similarity of the effects in trained and 5,7-DHT-injected animals may be due to massive release of serotonin elicited by 5,7-DHT injection. Our results suggest that serotonin release due to aversive conditionining or elicited by the neurotoxin administration triggers similar changes in resting membrane potential and AP threshold in response to bath applications of 5-HT or its precursor 5-HTP. PMID:29311833

Plasma Physics Applied (New Book)

NASA Astrophysics Data System (ADS)

Grabbe, Crockett

2007-03-01

0.5cm Plasma physics applications are one of the most rapidly growing fields in engineering & applied science today. The last decade alone has seen the rapid emergence of new applications such as dusty plasmas in the semiconductor and microchip industries, and plasma TVs. In addition, this last decade saw the achievement of the 50-year Lawson breakeven condition for fusion. With new discoveries in space plasma physics and applications to spacecraft for worldwide communication and space weather, as well as new applications being discovered, this diversity is always expanding. The new book Plasma Physics Applied reviews developments in several of these areas. Chapter 1 reviews the content and its authors, and is followed by a more comprehensive review of plasma physics applications in general in Chapter 2. Plasma applications in combustion and environmental uses are presented in Chapter 3. Lightning effects in planetary magnetospheres and potential application are described in Chapter 4. The area of dusty plasmas in both industrial and space plasmas and their applications are reviewed in Chapter 5. The particular area of Coulomb clusters in dusty plasmas is presented in Chapter 6. The variety of approaches to plasma confinement in magnetic devices for fusion are laid out in Chapter 7. Finally, an overview of plasma accelerator developments and their applications are presented in Chapter 8.

Potential exposures and risks from beryllium-containing products.

PubMed

Willis, Henry H; Florig, H Keith

2002-10-01

Beryllium is the strongest of the lightweight metals. Used primarily in military applications prior to the end of the Cold War, beryllium is finding new applications in many commercial products, including computers, telecommunication equipment, and consumer and automotive electronics. The use of beryllium in nondefense consumer applications is of concern because beryllium is toxic. Inhalation of beryllium dust or vapor causes a chronic lung disease in some individuals at concentrations as low as 0.01 microg/m3 in air. As beryllium enters wider commerce, it is prudent to ask what risks this might present to the general public and to workers downstream of the beryllium materials industry. We address this question by evaluating the potential for beryllium exposure from the manufacturing, use, recycle, and disposal of beryllium-containing products. Combining a market study with a qualitative exposure analysis, we determine which beryllium applications and life cycle phases have the largest exposure potential. Our analysis suggests that use and maintenance of the most common types of beryllium-containing products do not result in any obvious exposures of concern, and that maintenance activities result in greater exposures than product use. Product disposal has potential to present significant individual risks, but uncertainties concerning current and future routes of product disposal make it difficult to be definitive. Overall, additional exposure and dose-response data are needed to evaluate both the health significance of many exposure scenarios, and the adequacy of existing regulations to protect workers and the public. Although public exposures to beryllium and public awareness and concern regarding beryllium risks are currently low, beryllium risks have psychometric qualities that may lead to rapidly heightened public concern.

Parametric studies on droplet generation reproducibility for applications with biological relevant fluids

PubMed Central

Eichler, Marko; Römer, Robert; Grodrian, Andreas; Lemke, Karen; Nagel, Krees; Klages, Claus‐Peter; Gastrock, Gunter

2017-01-01

Abstract Although the great potential of droplet based microfluidic technologies for routine applications in industry and academia has been successfully demonstrated over the past years, its inherent potential is not fully exploited till now. Especially regarding to the droplet generation reproducibility and stability, two pivotally important parameters for successful applications, there is still a need for improvement. This is even more considerable when droplets are created to investigate tissue fragments or cell cultures (e.g. suspended cells or 3D cell cultures) over days or even weeks. In this study we present microfluidic chips composed of a plasma coated polymer, which allow surfactants‐free, highly reproducible and stable droplet generation from fluids like cell culture media. We demonstrate how different microfluidic designs and different flow rates (and flow rate ratios) affect the reproducibility of the droplet generation process and display the applicability for a wide variety of bio(techno)logically relevant media. PMID:29399017

Solar energy in California industry - Applications, characteristics and potential

NASA Technical Reports Server (NTRS)

Barbieri, R. H.; Pivirotto, D. S.

1978-01-01

Results of a survey to determine the potential applicability of solar thermal energy to industrial processes in California are presented. It is found that if the heat for all industrial processes at temperatures below 212 F were supplied by solar energy, total state energy consumption could be reduced by 100 trillion Btus (2%), while the use of solar energy in processes between 212 and 350 F could displace 500 trillion Btus. The issues and problems with which solar energy must contend are illustrated by a description of fluid milk processing operations. Solar energy application is found to be technically feasible for processes with thermal energy requirements below 212 F, with design, and degree of technical, economic and management feasibility being site specific. It is recommended that the state provide support for federal and industrial research, development and demonstration programs in order to stimulate acceptance of solar process heat application by industry.

Particle Swarm Optimization

NASA Technical Reports Server (NTRS)

Venter, Gerhard; Sobieszczanski-Sobieski Jaroslaw

2002-01-01

The purpose of this paper is to show how the search algorithm known as particle swarm optimization performs. Here, particle swarm optimization is applied to structural design problems, but the method has a much wider range of possible applications. The paper's new contributions are improvements to the particle swarm optimization algorithm and conclusions and recommendations as to the utility of the algorithm, Results of numerical experiments for both continuous and discrete applications are presented in the paper. The results indicate that the particle swarm optimization algorithm does locate the constrained minimum design in continuous applications with very good precision, albeit at a much higher computational cost than that of a typical gradient based optimizer. However, the true potential of particle swarm optimization is primarily in applications with discrete and/or discontinuous functions and variables. Additionally, particle swarm optimization has the potential of efficient computation with very large numbers of concurrently operating processors.

Electrical percolation in graphene–polymer composites

NASA Astrophysics Data System (ADS)

Marsden, A. J.; Papageorgiou, D. G.; Vallés, C.; Liscio, A.; Palermo, V.; Bissett, M. A.; Young, R. J.; Kinloch, I. A.

2018-07-01

Electrically conductive composites comprising polymers and graphene are extremely versatile and have a wide range of potential applications. The conductivity of these composites depends on the choice of polymer matrix, the type of graphene filler, the processing methodology, and any post-production treatments. In this review, we discuss the progress in graphene–polymer composites for electrical applications. Graphene filler types are reviewed, the progress in modelling these composites is outlined, the current optimal composites are presented, and the example of strain sensors is used to demonstrate their application.

Additive Manufacturing Technologies Used for Processing Polymers: Current Status and Potential Application in Prosthetic Dentistry.

PubMed

Revilla-León, Marta; Özcan, Mutlu

2018-04-22

There are 7 categories of additive manufacturing (AM) technologies, and a wide variety of materials can be used to build a CAD 3D object. The present article reviews the main AM processes for polymers for dental applications: stereolithography (SLA), digital light processing (DLP), material jetting (MJ), and material extrusion (ME). The manufacturing process, accuracy, and precision of these methods will be reviewed, as well as their prosthodontic applications. © 2018 by the American College of Prosthodontists.

NASA spinoffs to bioengineering and medicine

NASA Technical Reports Server (NTRS)

Rouse, Doris J.; Winfield, Daniel L.; Canada, S. Catherine

1989-01-01

The societal and economic benefits derived from the application of aerospace technology to improved health care are examined, and examples of the space-technology spinoffs are presented. Special attention is given to the applications of aerospace technology from digital image processing, space medicine and biology, microelectronics, optics and electrooptics, and ultrasonic imaging. The role of the NASA Technology Application Team in helping the potential technology users to identify and evaluate the technology transfer opportunities and to apply space technology in the field of medicine is discussed.

Molecular dynamics simulations for mechanical properties of borophene: parameterization of valence force field model and Stillinger-Weber potential

PubMed Central

Zhou, Yu-Ping; Jiang, Jin-Wu

2017-01-01

While most existing theoretical studies on the borophene are based on first-principles calculations, the present work presents molecular dynamics simulations for the lattice dynamical and mechanical properties in borophene. The obtained mechanical quantities are in good agreement with previous first-principles calculations. The key ingredients for these molecular dynamics simulations are the two efficient empirical potentials developed in the present work for the interaction of borophene with low-energy triangular structure. The first one is the valence force field model, which is developed with the assistance of the phonon dispersion of borophene. The valence force field model is a linear potential, so it is rather efficient for the calculation of linear quantities in borophene. The second one is the Stillinger-Weber potential, whose parameters are derived based on the valence force field model. The Stillinger-Weber potential is applicable in molecular dynamics simulations of nonlinear physical or mechanical quantities in borophene. PMID:28349983

Use of Desired Student Outcomes in Devising Agronomic Curricula.

ERIC Educational Resources Information Center

Grabau, L. J.

1990-01-01

Four models which illustrate potential orientations for baccalaureate programs in agronomy are presented. Included are Technical Training; Information Transfer; Principles Application; and Systems Agronomy. Strengths and weaknesses of each program are discussed. (CW)

Potential drawbacks in cell-assisted lipotransfer: A systematic review of existing reports (Review)

PubMed Central

HUANG, SHENG; ZHAO, WEILIANG; WANG, ZIHUA; TAO, KAI; LIU, XIAOYAN; CHANG, PENG

2016-01-01

Cell-assisted lipotransfer (CAL) has been widely used in various clinical applications, including breast augmentation following mammectomy, soft-tissue reconstruction and wound healing. However, the clinical application of CAL has been restricted due to the transplanted fat tissues being readily liquefied and absorbed. The present review examines 57 previously published studies involving CAL, including fat grafting or fat transfer with human adipose-stem cells in all known databases. Of these 57 articles, seven reported the clinical application of CAL. In the 57 studies, the majority of the fat tissues were obtained from the abdomen via liposuction of the seven clinical studies, four were performed in patients requiring breast augmentation, one in a patient requiring facial augmentation, one in a patient requiring soft tissue augmentation/reconstruction and one in a patient requiring fat in their upper arms. Despite the potential risks, there has been an increased demand for CAL in in cosmetic or aesthetic applications. Thus, criteria and guidelines are necessary for the clinical application of CAL technology. PMID:26677061

A technical analysis for cogeneration systems with potential applications in twelve California industrial plants. [energy saving heat-electricity utility systems

NASA Technical Reports Server (NTRS)

Moretti, V. C.; Davis, H. S.; Slonski, M. L.

1978-01-01

In a study sponsored by the State of California Energy Resources Conservation and Development Commission, 12 industrial plants in five utility districts were surveyed to assess the potential applications of the cogeneration of heat and electricity in California industry. Thermodynamic calculations were made for each plant in determining the energy required to meet the existing electrical and steam demands. The present systems were then compared to conceptual cogeneration systems specified for each plant. Overall energy savings were determined for the cogeneration applications. Steam and gas turbine topping cycle systems were considered as well as bottoming cycle systems. Types of industries studied were: pulp and paper, timber, cement, petroleum refining, enhanced oil recovery, foods processing, steel and glass

Grand Challenges and Future Opportunities for Metal–Organic Frameworks

PubMed Central

2017-01-01

Metal–organic frameworks (MOFs) allow compositional and structural diversity beyond conventional solid-state materials. Continued interest in the field is justified by potential applications of exceptional breadth, ranging from gas storage and separation, which takes advantage of the inherent pores and their volume, to electronic applications, which requires precise control of electronic structure. In this Outlook we present some of the pertinent challenges that MOFs face in their conventional implementations, as well as opportunities in less traditional areas. Here the aim is to discuss select design concepts and future research goals that emphasize nuances relevant to this class of materials as a whole. Particular emphasis is placed on synthetic aspects, as they influence the potential for MOFs in gas separation, electrical conductivity, and catalytic applications. PMID:28691066

The worldwide market for photovoltaics in the rural sector

NASA Technical Reports Server (NTRS)

Brainard, W. A.

1982-01-01

The worldwide market for stand-alone photovoltaic power systems in three specific segments of the rural sector were determined. The worldwide market for photovoltaic power systems for village power, cottage industry, and agricultural applications were addressed. The objectives of these studies were to: The market potential for small stand-alone photovoltaic power system in specific application areas was assessed. Technical, social and institutional barriers to PV utilization were identified. Funding sources available to potential users was also identified and marketing strategies appropriate for each sector were recommended to PV product manufacturers. The studies were prepared on the basis of data gathered from domestic sources and from field trips to representative countries. Both country-specific and sector-specific results are discussed, and broadly applicable barriers pertinent to international marketing of PV products are presented.

Grand Challenges and Future Opportunities for Metal–Organic Frameworks

DOE PAGES

Hendon, Christopher H.; Rieth, Adam J.; Korzyński, Maciej D.; ...

2017-06-06

Metal–organic frameworks (MOFs) allow compositional and structural diversity beyond conventional solid-state materials. Continued interest in the field is justified by potential applications of exceptional breadth, ranging from gas storage and separation, which takes advantage of the inherent pores and their volume, to electronic applications, which requires precise control of electronic structure. In this Outlook we present some of the pertinent challenges that MOFs face in their conventional implementations, as well as opportunities in less traditional areas. Here the aim is to discuss select design concepts and future research goals that emphasize nuances relevant to this class of materials as amore » whole. Particular emphasis is placed on synthetic aspects, as they influence the potential for MOFs in gas separation, electrical conductivity, and catalytic applications.« less

Assessment of Impact of Monoenergetic Photon Sources on Prioritized Nonproliferation Applications: Simulation Study Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Geddes, Cameron; Ludewigt, Bernhard; Valentine, John

Near-monoenergetic photon sources (MPSs) have the potential to improve sensitivity at greatly reduced dose in existing applications and enable new capabilities in other applications. MPS advantages include the ability to select energy, energy spread, flux, and pulse structures to deliver only the photons needed for the application, while suppressing extraneous dose and background. Some MPSs also offer narrow divergence photon beams which can target dose and/or mitigate scattering contributions to image contrast degradation. Current broad-band, bremsstrahlung photon sources (e.g., linacs and betatrons) deliver unnecessary dose that in some cases also interferes with the signature to be detected and/or restricts operations,more » and must be collimated (reducing flux) to generate narrow divergence beams. While MPSs can in principle resolve these issues, they are technically challenging to produce. Candidate MPS technologies for nonproliferation applications are now being developed, each of which have different properties (e.g. broad divergence vs. narrow). Within each technology, source parameters trade off against one another (e.g. flux vs. energy spread), representing a large operation space. To guide development, requirements for each application of interest must be defined and simulations conducted to define MPS parameters that deliver benefit relative to current systems. The present project conducted a broad assessment of potential nonproliferation applications where MPSs may provide new capabilities or significant performance enhancement (reported separately), which led to prioritization of several applications for detailed analysis. The applications prioritized were: cargo screening and interdiction of Special Nuclear Materials (SNM), detection of hidden SNM, treaty/dismantlement verification, and spent fuel dry storage cask content verification. High resolution imaging for stockpile stewardship was considered as a sub-area of the treaty topic, as it is also of interest for future treaty use. This report presents higher-fidelity calculations and modeling results to quantitatively evaluate the prioritized applications, and to derive the key MPS properties that drive application benefit. Simulations focused on the conventional signatures of radiography, photofission, and NRF to enable comparison to present methods and evaluation of benefit.« less

Reconstructing free-energy landscapes for nonequilibrium periodic potentials

NASA Astrophysics Data System (ADS)

López-Alamilla, N. J.; Jack, Michael W.; Challis, K. J.

2018-03-01

We present a method for reconstructing the free-energy landscape of overdamped Brownian motion on a tilted periodic potential. Our approach exploits the periodicity of the system by using the k -space form of the Smoluchowski equation and we employ an iterative approach to determine the nonequilibrium tilt. We reconstruct landscapes for a number of example potentials to show the applicability of the method to both deep and shallow wells and near-to- and far-from-equilibrium regimes. The method converges logarithmically with the number of Fourier terms in the potential.

Compact, Automated, Frequency-Agile Microspectrofluorimeter

NASA Technical Reports Server (NTRS)

Fernandez, Salvador M.; Guignon, Ernest F.

1995-01-01

Compact, reliable, rugged, automated cell-culture and frequency-agile microspectrofluorimetric apparatus developed to perform experiments involving photometric imaging observations of single live cells. In original application, apparatus operates mostly unattended aboard spacecraft; potential terrestrial applications include automated or semiautomated diagnosis of pathological tissues in clinical laboratories, biomedical instrumentation, monitoring of biological process streams, and portable instrumentation for testing biological conditions in various environments. Offers obvious advantages over present laboratory instrumentation.

Lunar NTR vehicle design and operations study

NASA Technical Reports Server (NTRS)

Hodge, John

1993-01-01

The results of a lunar nuclear thermal rocket (NTR) vehicle design and operations study are presented in text and graphic form. The objectives of the study were to evaluate the potential applications of a specific NTR design to past and current (First Lunar Outpost) mission profiles for piloted and cargo lunar missions, and to assess the applicability of utilizing lunar vehicle design concepts for Mars missions.

New method for qualitative simulations of water resources systems. 2. Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Antunes, M.P.; Seixas, M.J.; Camara, A.S.

1987-11-01

SLIN (Simulacao Linguistica) is a new method for qualitative dynamic simulation. As was presented previously, SLIN relies upon a categorical representation of variables which are manipulated by logical rules. Two applications to water resources systems are included to illustrate SLIN's potential usefulness: the environmental impact evaluation of a hydropower plant and the assessment of oil dispersion in the sea after a tanker wreck.

The role of pancreatic cancer-derived exosomes in cancer progress and their potential application as biomarkers.

PubMed

Jin, H; Wu, Y; Tan, X

2017-08-01

Pancreatic cancer is one of the most deadly cancers, with dismal prognosis due to its poor early detection rate and high metastatic rate. Thus, elucidation of the molecular mechanisms accounting for its metastasis and discovery of competent biomarkers is required. Exosomes are multivesicular body-derived small extracellular vesicles released by various cell types that serve as important message carriers during intercellular communication. They are also known to play critical roles during cancer-genesis, cancer-related immune reactions, and metastasis. They also possess promising potential as novel biomarkers for cancer early detection. Therefore, extensive studies on pancreatic cancer-derived exosomes are currently being performed because they hold the promising potential of elevating the overall survival rate of patients with pancreatic cancer. In the present review, we focus on the role of exosomes in pancreatic cancer-related immune reactions, metastasis, and complications, and on their potential application as pancreatic cancer biomarkers.

Marine microorganisms as potential biofactories for synthesis of metallic nanoparticles.

PubMed

Manivasagan, Panchanathan; Nam, Seung Yun; Oh, Junghwan

2016-11-01

The use of marine microorganisms as potential biofactories for green synthesis of metallic nanoparticles is a relatively new field of research with considerable prospects. This method is eco-friendly, time saving, and inexpensive and can be easily scaled up for large-scale synthesis. The increasing need to develop simple, nontoxic, clean, and environmentally safe production methods for nanoparticles and to decrease environmental impact, minimize waste, and increase energy productivity has become important in this field. Marine microorganisms are tiny organisms that live in marine ecosystems and account for >98% of biomass of the world's ocean. Marine microorganisms synthesize metallic nanoparticles either intracellularly or extracellularly. Marine microbially-produced metallic nanoparticles have received considerable attention in recent years because of their expected impact on various applications such as medicine, energy, electronic, and space industries. The present review discusses marine microorganisms as potential biofactories for the green synthesis of metallic nanoparticles and their potential applications.

Review on investigations of antisense oligonucleotides with the use of mass spectrometry.

PubMed

Studzińska, Sylwia

2018-01-01

Antisense oligonucleotides have been investigated as potential drugs for years. They inhibit target gene or protein expression. The present review summarizes their modifications, modes of action, and applications of liquid chromatography coupled with mass spectrometry for qualitative and quantitative analysis of these compounds. The most recent reports on a given topic were given prominence, while some early studies were reviewed in order to provide a theoretical background. The present review covers the issues of using ion-exchange chromatography, ion-pair reversed-phase high performance liquid chromatography and hydrophilic interaction chromatography for the separation of antisense oligonucleotides. The application of mass spectrometry was described with regard to the ionization type used for the determination of these potential therapeutics. Moreover, the current approaches and applications of mass spectrometry for quantitative analysis of antisense oligonucleotides and their metabolites as well as their impurities during in vitro and in vivo studies were discussed. Finally, certain conclusions and perspectives on the determination of therapeutic oligonucleotides in various samples were briefly described. Copyright © 2017 Elsevier B.V. All rights reserved.

Functionalized Gold Nanoparticles and Their Biomedical Applications

PubMed Central

Tiwari, Pooja M.; Vig, Komal; Dennis, Vida A.; Singh, Shree R.

2011-01-01

Metal nanoparticles are being extensively used in various biomedical applications due to their small size to volume ratio and extensive thermal stability. Gold nanoparticles (GNPs) are an obvious choice due to their amenability of synthesis and functionalization, less toxicity and ease of detection. The present review focuses on various methods of functionalization of GNPs and their applications in biomedical research. Functionalization facilitates targeted delivery of these nanoparticles to various cell types, bioimaging, gene delivery, drug delivery and other therapeutic and diagnostic applications. This review is an amalgamation of recent advances in the field of functionalization of gold nanoparticles and their potential applications in the field of medicine and biology. PMID:28348279

Electric Potential and Electric Field Imaging with Applications

NASA Technical Reports Server (NTRS)

Generazio, Ed

2016-01-01

The technology and techniques for remote quantitative imaging of electrostatic potentials and electrostatic fields in and around objects and in free space is presented. Electric field imaging (EFI) technology may be applied to characterize intrinsic or existing electric potentials and electric fields, or an externally generated electrostatic field may be used for (illuminating) volumes to be inspected with EFI. The baseline sensor technology, electric field sensor (e-sensor), and its construction, optional electric field generation (quasistatic generator), and current e-sensor enhancements (ephemeral e-sensor) are discussed. Demonstrations for structural, electronic, human, and memory applications are shown. This new EFI capability is demonstrated to reveal characterization of electric charge distribution, creating a new field of study that embraces areas of interest including electrostatic discharge mitigation, crime scene forensics, design and materials selection for advanced sensors, dielectric morphology of structures, inspection of containers, inspection for hidden objects, tether integrity, organic molecular memory, and medical diagnostic and treatment efficacy applications such as cardiac polarization wave propagation and electromyography imaging.

Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications

PubMed Central

Perchoux, Julien; Quotb, Adam; Atashkhooei, Reza; Azcona, Francisco J.; Ramírez-Miquet, Evelio E.; Bernal, Olivier; Jha, Ajit; Luna-Arriaga, Antonio; Yanez, Carlos; Caum, Jesus; Bosch, Thierry; Royo, Santiago

2016-01-01

Optical feedback interferometry (OFI) sensors are experiencing a consistent increase in their applications to biosensing due to their contactless nature, low cost and compactness, features that fit very well with current biophotonics research and market trends. The present paper is a review of the work in progress at UPC-CD6 and LAAS-CNRS related to the application of OFI to different aspects of biosensing, both in vivo and ex vivo. This work is intended to present the variety of opportunities and potential applications related to OFI that are available in the field. The activities presented are divided into two main sensing strategies: The measurement of optical path changes and the monitoring of flows, which correspond to sensing strategies linked to the reconstruction of changes of amplitude from the interferometric signal, and to classical Doppler frequency measurements, respectively. For optical path change measurements, measurements of transient pulses, usual in biosensing, together with the measurement of large displacements applied to designing palliative care instrumentation for Parkinson disease are discussed. Regarding the Doppler-based approach, progress in flow-related signal processing and applications in real-time monitoring of non-steady flows, human blood flow monitoring and OFI pressure myograph sensing will be presented. In all cases, experimental setups are discussed and results presented, showing the versatility of the technique. The described applications show the wide capabilities in biosensing of the OFI sensor, showing it as an enabler of low-cost, all-optical, high accuracy biomedical applications. PMID:27187406

Current Developments on Optical Feedback Interferometry as an All-Optical Sensor for Biomedical Applications.

PubMed

Perchoux, Julien; Quotb, Adam; Atashkhooei, Reza; Azcona, Francisco J; Ramírez-Miquet, Evelio E; Bernal, Olivier; Jha, Ajit; Luna-Arriaga, Antonio; Yanez, Carlos; Caum, Jesus; Bosch, Thierry; Royo, Santiago

2016-05-13

Optical feedback interferometry (OFI) sensors are experiencing a consistent increase in their applications to biosensing due to their contactless nature, low cost and compactness, features that fit very well with current biophotonics research and market trends. The present paper is a review of the work in progress at UPC-CD6 and LAAS-CNRS related to the application of OFI to different aspects of biosensing, both in vivo and ex vivo. This work is intended to present the variety of opportunities and potential applications related to OFI that are available in the field. The activities presented are divided into two main sensing strategies: The measurement of optical path changes and the monitoring of flows, which correspond to sensing strategies linked to the reconstruction of changes of amplitude from the interferometric signal, and to classical Doppler frequency measurements, respectively. For optical path change measurements, measurements of transient pulses, usual in biosensing, together with the measurement of large displacements applied to designing palliative care instrumentation for Parkinson disease are discussed. Regarding the Doppler-based approach, progress in flow-related signal processing and applications in real-time monitoring of non-steady flows, human blood flow monitoring and OFI pressure myograph sensing will be presented. In all cases, experimental setups are discussed and results presented, showing the versatility of the technique. The described applications show the wide capabilities in biosensing of the OFI sensor, showing it as an enabler of low-cost, all-optical, high accuracy biomedical applications.

Mapping Snow Depth with Automated Terrestrial Laser Scanning - Investigating Potential Applications

NASA Astrophysics Data System (ADS)

Adams, M. S.; Gigele, T.; Fromm, R.

2017-11-01

This contribution presents an automated terrestrial laser scanning (ATLS) setup, which was used during the winter 2016/17 to monitor the snow depth distribution on a NW-facing slope at a high-alpine study site. We collected data at high temporal [(sub-)daily] and spatial resolution (decimetre-range) over 0.8 km² with a Riegl LPM-321, set in a weather-proof glass fibre enclosure. Two potential ATLS-applications are investigated here: monitoring medium-sized snow avalanche events, and tracking snow depth change caused by snow drift. The results show the ATLS data's high explanatory power and versatility for different snow research questions.

Photovoltaic remote instrument applications: Assessment of the near-term market

NASA Technical Reports Server (NTRS)

Rosenblum, L.; Scudder, L. R.; Poley, W. A.; Bifano, W. J.

1977-01-01

A preliminary assessment of the near term market for photovoltaic remote instrument applications is presented. Among the potential users, two market sectors are considered: government and private. However, the majority of the remote systems studied are operated by or for the federal, state, or local governments. Environmental monitoring and surveillance remote instrument systems are discussed. Based on information obtained in this preliminary market survey, a domestic, civilian market of at least 1.3 MW sub pk is forecast for remote instrument systems. This estimate is exclusive of several potentially large scale markets for remote instruments which are identified but for which no hard data is available.

QCD at finite isospin chemical potential

NASA Astrophysics Data System (ADS)

Brandt, Bastian B.; Endrődi, Gergely; Schmalzbauer, Sebastian

2018-03-01

We investigate the properties of QCD at finite isospin chemical potential at zero and non-zero temperatures. This theory is not affected by the sign problem and can be simulated using Monte-Carlo techniques. With increasing isospin chemical potential and temperatures below the deconfinement transition the system changes into a phase where charged pions condense, accompanied by an accumulation of low modes of the Dirac operator. The simulations are enabled by the introduction of a pionic source into the action, acting as an infrared regulator for the theory, and physical results are obtained by removing the regulator via an extrapolation. We present an update of our study concerning the associated phase diagram using 2+1 flavours of staggered fermions with physical quark masses and the comparison to Taylor expansion. We also present first results for our determination of the equation of state at finite isospin chemical potential and give an example for a cosmological application. The results can also be used to gain information about QCD at small baryon chemical potentials using reweighting with respect to the pionic source parameter and the chemical potential and we present first steps in this direction.

Parenting stress and anger expression as predictors of child abuse potential.

PubMed

Rodriguez, C M; Green, A J

1997-04-01

To explore one potential pathway to physical child abuse, the present investigation used hierarchical regression analysis using measures of parenting stress and anger expression to jointly predict child abuse potential. The Parenting Stress Index, State-Trait Anger Expression Inventory, and the Child Abuse Potential Inventory were administered to two different samples of New Zealand parents. As expected, both studies revealed parenting stress and anger expression and were individually positively correlated with child abuse potential: the major finding involved the strong point contribution of parenting stress and anger expression in predicting Child Abuse Potential Inventory scores. Application of findings for intervention and prevention are discussed.

Status and applicability of solid polymer electrolyte technology to electrolytic hydrogen and oxygen production

NASA Technical Reports Server (NTRS)

Titterington, W. A.

1973-01-01

The solid polymer electrolyte (SPE) water electrolysis technology is presented as a potential energy conversion method for wind driven generator systems. Electrolysis life and performance data are presented from laboratory sized single cells (7.2 sq in active area) with high cell current density selected (1000 ASF) for normal operation.

76 FR 71341 - BASINS and WEPP Climate Assessment Tools: Case Study Guide to Potential Applications

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-17

... report presents a series of short case studies designed to illustrate the capabilities of these tools for... change impacts on water. This report presents a series of short case studies using the BASINS and WEPP climate assessment tools. The case studies are designed to illustrate the capabilities of these tools for...

Evaluation of Braided Stiffener Concepts for Transport Aircraft Wing Structure Applications

NASA Technical Reports Server (NTRS)

Deaton, Jerry W.; Dexter, H. Benson (Editor); Markus, Alan; Rohwer, Kim

1995-01-01

Braided composite materials have potential for application in aircraft structures. Stiffeners, wing spars, floor beams, and fuselage frames are examples where braided composites could find application if cost effective processing and damage requirements are met. Braiding is an automated process for obtaining near-net shape preforms for fabrication of components for structural applications. Previous test results on braided composite materials obtained at NASA Langley indicate that damage tolerance requirements can be met for some applications. In addition, the braiding industry is taking steps to increase the material through-put to be more competitive with other preform fabrication processes. Data are presented on the compressive behavior of three braided stiffener preform fabric constructions as determined from individual stiffener crippling test and three stiffener wide panel tests. Stiffener and panel fabrication are described and compression data presented for specimens tested with and without impact damage. In addition, data are also presented on the compressive behavior of the stitched stiffener preform construction currently being used by McDonnell Douglas Aerospace in the NASA ACT wing development program.

Safety of High Speed Guided Ground Transportation Systems: Work Breakdown Structure

DOT National Transportation Integrated Search

1994-11-30

This report provides a systems approach to the assessment, evaluation and application of high-speed guided ground transportation (HSGGT) safety criteria and : presents one potential methodology by combining a work breakdown structure (WBS) : approach...

Accessibility Measures: Formulation Considerations and Current Applications

DOT National Transportation Integrated Search

2000-09-01

This report examines micro-scale and macro-scale factors for inclusion in an ideal accessibility measure. Their potential influence on the evaluation of mode choice and destination choice is discussed. Availability in Texas' major cities is presented...

Magnetic polyoxometalates: from molecular magnetism to molecular spintronics and quantum computing.

PubMed

Clemente-Juan, Juan M; Coronado, Eugenio; Gaita-Ariño, Alejandro

2012-11-21

In this review we discuss the relevance of polyoxometalate (POM) chemistry to provide model objects in molecular magnetism. We present several potential applications in nanomagnetism, in particular, in molecular spintronics and quantum computing.

Potential of Diesel Engine, Emission Technology

DOT National Transportation Integrated Search

1980-03-01

This report surveys diesel engine emission technologies applicable to passenger cars and light trucks. The general design and operating features are presented and discussed. Current and state-of-the-art concepts are reviewed with the focus on control...

Integrating Residential Photovoltaics With Power Lines

NASA Technical Reports Server (NTRS)

Borden, C. S.

1985-01-01

Report finds rooftop solar-cell arrays feed excess power to electric-utility grid for fee are potentially attractive large-scale application of photovoltaic technology. Presents assessment of breakeven costs of these arrays under variety of technological and economic assumptions.

Advanced Sensors and Controls for Building Applications: Market Assessment and Potential R&D Pathways

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brambley, M. R.; Haves, P.; McDonald, S. C.

2005-04-01

This document provides a market assessment of existing building sensors and controls and presents a range of technology pathways (R&D options) for pursuing advanced sensors and building control strategies.

Computer programs: Electronic circuit design criteria: A compilation

NASA Technical Reports Server (NTRS)

1973-01-01

A Technology Utilization Program for the dissemination of information on technological developments which have potential utility outside the aerospace community is presented. The 21 items reported herein describe programs that are applicable to electronic circuit design procedures.

Biomimetics - using nature as an inspiring model for innovation

NASA Technical Reports Server (NTRS)

Bar-Cohen, Yoseph

2006-01-01

In this presentation, various aspects of the field of biomimetics will be reviewed, examples of inspiring biological models and practical applications will be described, and challenges and potential direction of the field will be discussed.

Judgement heuristics and bias in evidence interpretation: The effects of computer generated exhibits.

PubMed

Norris, Gareth

2015-01-01

The increasing use of multi-media applications, trial presentation software and computer generated exhibits (CGE) has raised questions as to the potential impact of the use of presentation technology on juror decision making. A significant amount of the commentary on the manner in which CGE exerts legal influence is largely anecdotal; empirical examinations too are often devoid of established theoretical rationalisations. This paper will examine a range of established judgement heuristics (for example, the attribution error, representativeness, simulation), in order to establish their appropriate application for comprehending legal decisions. Analysis of both past cases and empirical studies will highlight the potential for heuristics and biases to be restricted or confounded by the use of CGE. The paper will conclude with some wider discussion on admissibility, access to justice, and emerging issues in the use of multi-media in court. Copyright © 2015 Elsevier Ltd. All rights reserved.

Modeling Images of Natural 3D Surfaces: Overview and Potential Applications

NASA Technical Reports Server (NTRS)

Jalobeanu, Andre; Kuehnel, Frank; Stutz, John

2004-01-01

Generative models of natural images have long been used in computer vision. However, since they only describe the of 2D scenes, they fail to capture all the properties of the underlying 3D world. Even though such models are sufficient for many vision tasks a 3D scene model is when it comes to inferring a 3D object or its characteristics. In this paper, we present such a generative model, incorporating both a multiscale surface prior model for surface geometry and reflectance, and an image formation process model based on realistic rendering, the computation of the posterior model parameter densities, and on the critical aspects of the rendering. We also how to efficiently invert the model within a Bayesian framework. We present a few potential applications, such as asteroid modeling and Planetary topography recovery, illustrated by promising results on real images.

Piezo‐Phototronic Effect Enhanced Flexible Solar Cells Based on n‐ZnO/p‐SnS Core–Shell Nanowire Array

PubMed Central

Zhu, Laipan; Wang, Longfei; Xue, Fei; Chen, Libo; Fu, Jianqiang; Feng, Xiaolong; Li, Tianfeng

2016-01-01

The piezo‐phototronic effect is about the enhanced separation, transport, and recombination of the photogenerated carriers using the piezoelectric polarization charges present in piezoelectric‐semiconductor materials. Here, it is presented that the piezo‐phototronic effect can be effectively applied to improve the relative conversion efficiency of a flexible solar cell based on n‐ZnO/p‐SnS core–shell nanowire array for 37.3% under a moderate vertical pressure. The performance of the solar cell can be effectively enhanced by a gentle bending of the device, showing its potential for application in curly geometries. This study not only adds further understanding about the concept of increasing solar energy conversion efficiency via piezo‐phototronic effect, but also demonstrates the great potential of piezo‐phototronic effect in the application of large‐scale, flexible, and lightweight nanowire array solar cells. PMID:28105394

Piezo-Phototronic Effect Enhanced Flexible Solar Cells Based on n-ZnO/p-SnS Core-Shell Nanowire Array.

PubMed

Zhu, Laipan; Wang, Longfei; Xue, Fei; Chen, Libo; Fu, Jianqiang; Feng, Xiaolong; Li, Tianfeng; Wang, Zhong Lin

2017-01-01

The piezo-phototronic effect is about the enhanced separation, transport, and recombination of the photogenerated carriers using the piezoelectric polarization charges present in piezoelectric-semiconductor materials. Here, it is presented that the piezo-phototronic effect can be effectively applied to improve the relative conversion efficiency of a flexible solar cell based on n-ZnO/p-SnS core-shell nanowire array for 37.3% under a moderate vertical pressure. The performance of the solar cell can be effectively enhanced by a gentle bending of the device, showing its potential for application in curly geometries. This study not only adds further understanding about the concept of increasing solar energy conversion efficiency via piezo-phototronic effect, but also demonstrates the great potential of piezo-phototronic effect in the application of large-scale, flexible, and lightweight nanowire array solar cells.

Wireless power using magnetic resonance coupling for neural sensing applications

NASA Astrophysics Data System (ADS)

Yoon, Hargsoon; Kim, Hyunjung; Choi, Sang H.; Sanford, Larry D.; Geddis, Demetris; Lee, Kunik; Kim, Jaehwan; Song, Kyo D.

2012-04-01

Various wireless power transfer systems based on electromagnetic coupling have been investigated and applied in many biomedical applications including functional electrical stimulation systems and physiological sensing in humans and animals. By integrating wireless power transfer modules with wireless communication devices, electronic systems can deliver data and control system operation in untethered freely-moving conditions without requiring access through the skin, a potential source of infection. In this presentation, we will discuss a wireless power transfer module using magnetic resonance coupling that is specifically designed for neural sensing systems and in-vivo animal models. This research presents simple experimental set-ups and circuit models of magnetic resonance coupling modules and discusses advantages and concerns involved in positioning and sizing of source and receiver coils compared to conventional inductive coupling devices. Furthermore, the potential concern of tissue heating in the brain during operation of the wireless power transfer systems will also be addressed.

Potential applications of a high altitude powered platform in the ocean/coastal zone community

NASA Technical Reports Server (NTRS)

Escoe, D.; Rigterink, P.; Oberholtzer, J. D.

1979-01-01

The results of a survey of the ocean/coastal zone community conducted for the NASA Wallops Flight Center to identify potential applications of a high altitude powered platform (HAPP) are presented. Such a platform would stationkeep at 70,000 feet for up to a year over a given location and make frequent high resolution observations, or serve as a regional communications link. The survey results indicate user interest among scientific researchers, operational agencies and private industry. It is felt that such a platform would combine the desirable characteristics of both geostationary satellites (wide area, frequent observation) and aircraft (high resolution). As a result a concept for an operational HAPP system in the form of a 'mesoscale geostationary satellite' system evolved. Such a system could employ many of the same technologies used in current NASA and NOAA geostationary satellite programs. A set of generalized instrument requirements for HAPP borne sensors is also presented.

A multiplex protein-free lateral flow assay for detection of microRNAs based on unmodified molecular beacons.

PubMed

Javani, Atefeh; Javadi-Zarnaghi, Fatemeh; Rasaee, Mohammad Javad

2017-11-15

Lateral flow assays (LFAs) have promising potentials for point-of-care applications. Recently, many LFAs have been reported that are based on hybridization of oligonucleotide strands. Mostly, biotinylated capture DNAs are immobilized on the surface of a nitrocellulose membrane via streptavidin interactions. During the assay, stable colorful complexes get formed that are visible by naked eyes. Here, we present an inexpensive and unique design of LFA that applies unmodified oligonucleotides at capture lines. The presented LFA do not utilize streptavidin or any other affinity protein. We employ structural switch of molecular beacons (MB) in combination with base stacking hybridization (BSH) phenomenon. The unique design of the reported LFA provided high selectivity for target oligonucleotides. We validated potential applications of the system for detection of DNA mimics of two microRNAs in multiplex assays. Copyright © 2017 Elsevier Inc. All rights reserved.

Polymer-Ceramic Composite Materials for Pyroelectric Infrared Detectors: An Overview

NASA Technical Reports Server (NTRS)

Aggarwal, M. D; Currie, J. R.; Penn, B. G.; Batra, A. K.; Lal, R. B.

2007-01-01

Ferroelectrics:Polymer composites can be considered an established substitute for conventional electroceramics and ferroelectric polymers. The composites have a unique blend of polymeric properties such as mechanical flexibility, high strength, formability, and low cost, with the high electro-active properties of ceramic materials. They have attracted considerable interest because of their potential use in pyroelectric infrared detecting devices and piezoelectric transducers. These flexible sensors and transducers may eventually be useful for their health monitoring applications for NASA crew launch vehicles and crew exploration vehicles being developed. In the light of many technologically important applications in this field, it is worthwhile to present an overview of the pyroelectric infrared detector theory, models to predict dielectric behavior and pyroelectric coefficient, and the concept of connectivity and fabrication techniques of biphasic composites. An elaborate review of Pyroelectric-Polymer composite materials investigated to date for their potential use in pyroelectric infrared detectors is presented.

ls1 mardyn: The Massively Parallel Molecular Dynamics Code for Large Systems.

PubMed

Niethammer, Christoph; Becker, Stefan; Bernreuther, Martin; Buchholz, Martin; Eckhardt, Wolfgang; Heinecke, Alexander; Werth, Stephan; Bungartz, Hans-Joachim; Glass, Colin W; Hasse, Hans; Vrabec, Jadran; Horsch, Martin

2014-10-14

The molecular dynamics simulation code ls1 mardyn is presented. It is a highly scalable code, optimized for massively parallel execution on supercomputing architectures and currently holds the world record for the largest molecular simulation with over four trillion particles. It enables the application of pair potentials to length and time scales that were previously out of scope for molecular dynamics simulation. With an efficient dynamic load balancing scheme, it delivers high scalability even for challenging heterogeneous configurations. Presently, multicenter rigid potential models based on Lennard-Jones sites, point charges, and higher-order polarities are supported. Due to its modular design, ls1 mardyn can be extended to new physical models, methods, and algorithms, allowing future users to tailor it to suit their respective needs. Possible applications include scenarios with complex geometries, such as fluids at interfaces, as well as nonequilibrium molecular dynamics simulation of heat and mass transfer.

MEMS FPI-based smartphone hyperspectral imager

NASA Astrophysics Data System (ADS)

Rissanen, Anna; Saari, Heikki; Rainio, Kari; Stuns, Ingmar; Viherkanto, Kai; Holmlund, Christer; Näkki, Ismo; Ojanen, Harri

2016-05-01

This paper demonstrates a mobile phone- compatible hyperspectral imager based on a tunable MEMS Fabry-Perot interferometer. The realized iPhone 5s hyperspectral imager (HSI) demonstrator utilizes MEMS FPI tunable filter for visible-range, which consist of atomic layer deposited (ALD) Al2O3/TiO2-thin film Bragg reflectors. Characterization results for the mobile phone hyperspectral imager utilizing MEMS FPI chip optimized for 500 nm is presented; the operation range is λ = 450 - 550 nm with FWHM between 8 - 15 nm. Also a configuration of two cascaded FPIs (λ = 500 nm and λ = 650 nm) combined with an RGB colour camera is presented. With this tandem configuration, the overall wavelength tuning range of MEMS hyperspectral imagers can be extended to cover a larger range than with a single FPI chip. The potential applications of mobile hyperspectral imagers in the vis-NIR range include authentication, counterfeit detection and potential health/wellness and food sensing applications.

Synthesis of magnetic thermosensitive microcontainers for enzyme immobilization

NASA Astrophysics Data System (ADS)

Wang, Jianzhi; Zhao, Guanghui; Wang, Xinyu; Peng, Xiaomen; Li, Yanfeng

2015-05-01

We present a new approach for the fabrication of magnetic thermoresponsive polymer microcapsules with mobile magnetic spherical cores. The microcontainers form fried-egg-like structures with a polymer shell layer of 50 nm due to the existence of hollow cavities. The microcontainers undergo a temperature-induced volume phase transition upon changing the temperature and present an impressive magnetic response. The magnetic saturation of these smart microcontainers (42 emu/g) is high enough to meet most requirements of bioapplications. To further investigate the potential application of these smart microcontainers in biotechnology, Candida rugosa lipase was selected for the enzyme immobilization process. The immobilized lipase exhibited excellent thermal stability and reusability in comparison with the free enzyme. The adsorption/release of the lipase from the microcontainers can be controlled by the environmental temperature and magnetic force, thus, offering new potential applications such as in controlled drug delivery, bioseparation, and catalysis.

Evaluation of homogeneous electrocatalysts by cyclic voltammetry.

PubMed

Rountree, Eric S; McCarthy, Brian D; Eisenhart, Thomas T; Dempsey, Jillian L

2014-10-06

The pursuit of solar fuels has motivated extensive research on molecular electrocatalysts capable of evolving hydrogen from protic solutions, reducing CO2, and oxidizing water. Determining accurate figures of merit for these catalysts requires the careful and appropriate application of electroanalytical techniques. This Viewpoint first briefly presents the fundamentals of cyclic voltammetry and highlights practical experimental considerations before focusing on the application of cyclic voltammetry for the characterization of electrocatalysts. Key metrics for comparing catalysts, including the overpotential (η), potential for catalysis (E(cat)), observed rate constant (k(obs)), and potential-dependent turnover frequency, are discussed. The cyclic voltammetric responses for a general electrocatalytic one-electron reduction of a substrate are presented along with methods to extract figures of merit from these data. The extension of this analysis to more complex electrocatalytic schemes, such as those responsible for H2 evolution and CO2 reduction, is then discussed.

Microfabricated Chemical Gas Sensors and Sensor Arrays for Aerospace Applications

NASA Technical Reports Server (NTRS)

Hunter, Gary W.

2005-01-01

Aerospace applications require the development of chemical sensors with capabilities beyond those of commercially available sensors. In particular, factors such as minimal sensor size, weight, and power consumption are particularly important. Development areas which have potential aerospace applications include launch vehicle leak detection, engine health monitoring, and fire detection. Sensor development for these applications is based on progress in three types of technology: 1) Micromachining and microfabrication (Microsystem) technology to fabricate miniaturized sensors; 2) The use of nanocrystalline materials to develop sensors with improved stability combined with higher sensitivity; 3) The development of high temperature semiconductors, especially silicon carbide. This presentation discusses the needs of space applications as well as the point-contact sensor technology and sensor arrays being developed to address these needs. Sensors to measure hydrogen, hydrocarbons, nitrogen oxides (NO,), carbon monoxide, oxygen, and carbon dioxide are being developed as well as arrays for leak, fire, and emissions detection. Demonstrations of the technology will also be discussed. It is concluded that microfabricated sensor technology has significant potential for use in a range of aerospace applications.

Cryocoolers: the state of the art and recent developments.

PubMed

Radebaugh, Ray

2009-04-22

Cryocooler performance and reliability are continually improving. Consequently, they are more and more frequently implemented by physicists in their laboratory experiments or for commercial and space applications. The five kinds of cryocoolers most commonly used to provide cryogenic temperatures for various applications are the Joule-Thomson, Brayton, Stirling, Gifford-McMahon, and pulse tube cryocoolers. Many advances in all types have occurred in the past 20 years that have allowed all of them to be used for a wide variety of applications. The present state of the art and on-going developments of these cryocoolers are reviewed in this paper. In the past five years new research on these cryocoolers has offered the potential to significantly improve them and make them suitable for even more applications. The general trend of this new cryocooler research is also presented.

Emerging Applications of Ceramic and Metal Matrix Composites

NASA Astrophysics Data System (ADS)

Krishnamoorthy, Divya; Ramolina, Dheeyana; Sandou, Sherleena

2012-07-01

Almost 500 papers were presented during the 43 sessions of the 27th Annual Cocoa Beach Conference & Exposition on Advanced Ceramics & Composites, which was organized by the Engineering Ceramics Division of the American Ceramic Society and sponsored by several federal agencies: NASA Glenn Research Center, the Army Research Office, the Department of Energy, and the Air Force Office of Scientific Research. Many of these papers focused on composites, both ceramic and metal matrix, and discussed mechanical behavior, design, fibers/interfaces, processing, and applications. Potential applications under development include components for armor, nuclear energy, and automobiles. A few of these applications have reached commercialization.

Survey of multi-function display and control technology

NASA Technical Reports Server (NTRS)

Spiger, R. J.; Farrell, R. J.; Tonkin, M. H.

1982-01-01

The NASA orbiter spacecraft incorporates a complex array of systems, displays and controls. The incorporation of discrete dedicated controls into a multi-function display and control system (MFDCS) offers the potential for savings in weight, power, panel space and crew training time. The technology applicable to the development of a MFDCS for orbiter application is surveyed. Technology thought to be applicable presently or in the next five years is highlighted. Areas discussed include display media, data handling and processing, controls and operator interactions and the human factors considerations which are involved in a MFDCS design. Several examples of applicable MFDCS technology are described.

Overview of detector technologies for EO/IR sensing applications

NASA Astrophysics Data System (ADS)

Sood, Ashok K.; Zeller, John W.; Welser, Roger E.; Puri, Yash R.; Lewis, Jay S.; Dhar, Nibir K.; Wijewarnasuriya, Priyalal

2016-05-01

Optical sensing technology is critical for optical communication, defense and security applications. Advances in optoelectronics materials in the UV, Visible and Infrared, using nanostructures, and use of novel materials such as CNT and Graphene have opened doors for new approaches to apply device design methodology that are expected to offer enhanced performance and low cost optical sensors in a wide range of applications. This paper is intended to review recent advancements and present different device architectures and analysis. The chapter will briefly introduce the basics of UV and Infrared detection physics and various wave bands of interest and their characteristics [1, 2] We will cover the UV band (200-400 nm) and address some of the recent advances in nanostructures growth and characterization using ZnO/MgZnO based technologies and their applications. Recent advancements in design and development of CNT and Graphene based detection technologies have shown promise for optical sensor applications. We will present theoretical and experimental results on these device and their potential applications in various bands of interest.

Potential Applications of Smart Multifunctional Wearable Materials to Gerontology.

PubMed

Armstrong, David G; Najafi, Bijan; Shahinpoor, Mohsen

2017-01-01

Smart multifunctional materials can play a constructive role in addressing some very important aging-related issues. Aging affects the ability of older adults to continue to live safely and economically in their own residences for as long as possible. Thus, there will be a greater need for preventive, acute, rehabilitative, and long-term health care services for older adults as well as a need for tools to enable them to function independently during daily activities. The objective of this paper is, thus, to present a comprehensive review of some potential smart materials and their areas of applications to gerontology. Thus, brief descriptions of various currently available multifunctional smart materials and their possible applications to aging-related problems are presented. It is concluded that some of the most important applications to geriatrics may be in various sensing scenarios to collect health-related feedback or information and provide personalized care. Further described are the applications of wearable technologies to aging-related needs, including devices for home rehabilitation, remote monitoring, social well-being, frailty monitoring, monitoring of diabetes and wound healing and fall detection or prediction. It is also concluded that wearable technologies, when combined with an appropriate application and with appropriate feedback, may help improve activities and functions of older patients with chronic diseases. Finally, it is noted that methods developed to measure what one collectively manages in this population may provide a foundation to establish new definitions of quality of life. © 2017 S. Karger AG, Basel.

Hydropower Resource Assessment of Brazilian Streams

DOE Office of Scientific and Technical Information (OSTI.GOV)

Douglas G. Hall

The Idaho National Laboratory (INL) in collaboration with the U.S. Geological Survey (USGS) with the assistance of the Empresa de Pesquisa Energetica (EPE) and the Agencia Nacional de Energia Electrica (ANEEL) has performed a comprehensive assessment of the hydropower potential of all Brazilian natural streams. The methodology by which the assessment was performed is described. The results of the assessment are presented including an estimate of the hydropower potential for all of Brazil, and the spatial distribution of hydropower potential thus providing results on a state by state basis. The assessment results have been incorporated into a geographic information systemmore » (GIS) application for the Internet called the Virtual Hydropower Prospector do Brasil. VHP do Brasil displays potential hydropower sites on a map of Brazil in the context of topography and hydrography, existing power and transportation infrastructure, populated places and political boundaries, and land use. The features of the application, which includes tools for finding and selecting potential hydropower sites and other features and displaying their attributes, is fully described.« less

An Investigation of Applications for Thermodynamic Work Potential Methods: Working Tables and Charts for Estimation of Thermodynamic Work Potential in Equilibrium Mixtures of Jet-A and Air

NASA Technical Reports Server (NTRS)

Mavris, Dimitri; Roth, Bryce; McDonald, Rob

2002-01-01

The objective of this report is to provide a tool to facilitate the application of thermodynamic work potential methods to aircraft and engine analysis. This starts with a discussion of the theoretical background underlying these methods, which is then used to derive various equations useful for thermodynamic analysis of aircraft engines. The work potential analysis method is implemented in the form of a set of working charts and tables that can be used to graphically evaluate work potential stored in high-enthalpy gas. The range of validity for these tables is 300 to 36,000 R, pressures between between 0.01 atm and 100 atm, and fuel-air ratios from zero to stoichiometric. The derivations and charts assume mixtures of Jet-A and air as the working fluid. The thermodynamic properties presented in these charts were calculated based upon standard thermodynamic curve fits.

The Application of Surface Potential Test on Hand-making Insulation for Generator Stator End-winding

NASA Astrophysics Data System (ADS)

Lu, Zhu-mao; Liu, Qing; Wang, Tian-zheng; Bai, Lu; Li, Yan-peng

2017-05-01

This paper presents the advantage of surface potential test on hand-making insulation for generator stator end-winding insulation detection, compared with DC or AC withstand voltage test, also details the test principle, connection method and test notes. And through the case, surface potential test on hand-making insulation proved effective for insulation quality detection after generator stator end-winding maintenance, and the experimental data is useful and reliable for the electrical equipment operation and maintenance in the power plant.

Fast Model Generalized Pseudopotential Theory Interatomic Potential Routine

DOE Office of Scientific and Technical Information (OSTI.GOV)

2015-03-18

MGPT is an unclassified source code for the fast evaluation and application of quantum-based MGPT interatomic potentials for mrtals. The present version of MGPT has been developed entirely at LLNL, but is specifically designed for implementation in the open-source molecular0dynamics code LAMMPS maintained by Sandia National Laboratories. Using MGPT in LAMMPS, with separate input potential data, one can perform large-scale atomistic simulations of the structural, thermodynamic, defeat and mechanical properties of transition metals with quantum-mechanical realism.

A review of spectral methods

NASA Technical Reports Server (NTRS)

Lustman, L.

1984-01-01

An outline for spectral methods for partial differential equations is presented. The basic spectral algorithm is defined, collocation are emphasized and the main advantage of the method, the infinite order of accuracy in problems with smooth solutions are discussed. Examples of theoretical numerical analysis of spectral calculations are presented. An application of spectral methods to transonic flow is presented. The full potential transonic equation is among the best understood among nonlinear equations.

Development of high frequency pulse tube cryocoolers for space applications

NASA Astrophysics Data System (ADS)

Dang, Haizheng

2012-06-01

This paper reviews recent advances in high frequency pulse tube cryocoolers developed in SITP/CAS to provide high reliability, low-noise and long life cooling for potential space applications. The advances in understanding the cooler mechanism and minimizing irreversible losses in various components are described, which have made a great contribution to the improved efficiencies. At present, the operating temperatures cover from 30 K to 200 K and the cooling capacities vary from hundreds of milliwatts to over 20 W to meet a variety of requirements. Some typical cryocooler development programs are introduced and a brief overview of the updated data package is presented. The proposed applications, design approaches, research advances, the major problems and the efforts to overcome them are described.

PET/MRI for neurologic applications.

PubMed

Catana, Ciprian; Drzezga, Alexander; Heiss, Wolf-Dieter; Rosen, Bruce R

2012-12-01

PET and MRI provide complementary information in the study of the human brain. Simultaneous PET/MRI data acquisition allows the spatial and temporal correlation of the measured signals, creating opportunities impossible to realize using stand-alone instruments. This paper reviews the methodologic improvements and potential neurologic and psychiatric applications of this novel technology. We first present methods for improving the performance and information content of each modality by using the information provided by the other technique. On the PET side, we discuss methods that use the simultaneously acquired MRI data to improve the PET data quantification. On the MRI side, we present how improved PET quantification can be used to validate several MRI techniques. Finally, we describe promising research, translational, and clinical applications that can benefit from these advanced tools.

Towards Laser Cooling Trapped Ions with Telecom Light

NASA Astrophysics Data System (ADS)

Dungan, Kristina; Becker, Patrick; Donoghue, Liz; Liu, Jackie; Olmschenk, Steven

2015-05-01

Quantum information has many potential applications in communication, atomic clocks, and the precision measurement of fundamental constants. Trapped ions are excellent candidates for applications in quantum information because of their isolation from external perturbations, and the precise control afforded by laser cooling and manipulation of the quantum state. For many applications in quantum communication, it would be advantageous to interface ions with telecom light. We present progress towards laser cooling and trapping of doubly-ionized lanthanum, which should require only infrared, telecom-compatible light. Additionally, we present progress on optimization of a second-harmonic generation cavity for laser cooling and trapping barium ions, for future sympathetic cooling experiments. This research is supported by the Army Research Office, Research Corporation for Science Advancement, and Denison University.

Automation of experimental research of waveguide paths induction soldering

NASA Astrophysics Data System (ADS)

Tynchenko, V. S.; Petrenko, V. E.; Kukartsev, V. V.; Tynchenko, V. V.; Antamoshkin, O. A.

2018-05-01

The article presents an automated system of experimental studies of the waveguide paths induction soldering process. The system is a part of additional software for a complex of automated control of the technological process of induction soldering of thin-walled waveguide paths from aluminum alloys, expanding its capabilities. The structure of the software product, the general appearance of the controls and the potential application possibilities are presented. The utility of the developed application by approbation in a series of field experiments was considered and justified. The application of the experimental research system makes it possible to improve the process under consideration, providing the possibility of fine-tuning the control regulators, as well as keeping the statistics of the soldering process in a convenient form for analysis.

Electric field stimulation setup for photoemission electron microscopes.

PubMed

Buzzi, M; Vaz, C A F; Raabe, J; Nolting, F

2015-08-01

Manipulating magnetisation by the application of an electric field in magnetoelectric multiferroics represents a timely issue due to the potential applications in low power electronics and the novel physics involved. Thanks to its element sensitivity and high spatial resolution, X-ray photoemission electron microscopy is a uniquely suited technique for the investigation of magnetoelectric coupling in multiferroic materials. In this work, we present a setup that allows for the application of in situ electric and magnetic fields while the sample is analysed in the microscope. As an example of the performances of the setup, we present measurements on Ni/Pb(Mg(0.66)Nb(0.33))O3-PbTiO3 and La(0.7)Sr(0.3)MnO3/PMN-PT artificial multiferroic nanostructures.

Spacecraft Health Automated Reasoning Prototype (SHARP): The fiscal year 1989 SHARP portability evaluations task for NASA Solar System Exploration Division's Voyager project

NASA Technical Reports Server (NTRS)

Atkinson, David J.; Doyle, Richard J.; James, Mark L.; Kaufman, Tim; Martin, R. Gaius

1990-01-01

A Spacecraft Health Automated Reasoning Prototype (SHARP) portability study is presented. Some specific progress is described on the portability studies, plans for technology transfer, and potential applications of SHARP and related artificial intelligence technology to telescience operations. The application of SHARP to Voyager telecommunications was a proof-of-capability demonstration of artificial intelligence as applied to the problem of real time monitoring functions in planetary mission operations. An overview of the design and functional description of the SHARP system is also presented as it was applied to Voyager.

Environmental monitoring techniques and wave energy potential assessment: an integrated approach for planning marine energy conversion schemes in the northern Tyrrhenian sea, Italy

NASA Astrophysics Data System (ADS)

Scanu, Sergio; Peviani, Maximo; Carli, Filippo Maria; Paladini de Mendoza, Francesco; Piermattei, Viviana; Bonamano, Simone; Marcelli, Marco

2015-04-01

This work proposes a multidisciplinary approach in which wave power potential maps are used as baseline for the application of environmental monitoring techniques identified through the use of a Database for Environmental Monitoring Techniques and Equipment (DEMTE), derived in the frame of the project "Marine Renewables Infrastructure Network for Emerging Energy Technologies" (Marinet - FP7). This approach aims to standardize the monitoring of the marine environment in the event of installation, operation and decommissioning of Marine Energy Conversion Systems. The database has been obtained through the collection of techniques and instrumentation available among the partners of the consortium, in relation with all environmental marine compounds potentially affected by any impacts. Furthermore in order to plan marine energy conversion schemes, the wave potential was assessed at regional and local scales using the numerical modelling downscaling methodology. The regional scale lead to the elaboration of the Italian Wave Power Atlas, while the local scale lead to the definition of nearshore hot spots useful for the planning of devices installation along the Latium coast. The present work focus in the application of environmental monitoring techniques identified in the DEMTE, in correspondence of the hotspot derived from the wave potential maps with particular reference to the biological interaction of the devices and the management of the marine space. The obtained results are the bases for the development of standardized procedures which aims to an effective application of marine environmental monitoring techniques during the installation, operation and decommissioning of Marine Energy Conversion Systems. The present work gives a consistent contribution to overcome non-technological barriers in the concession procedures, as far as the protection of the marine environment is of concern.

Numerical solutions of incompressible Navier-Stokes equations using modified Bernoulli's law

NASA Astrophysics Data System (ADS)

Shatalov, A.; Hafez, M.

2003-11-01

Simulations of incompressible flows are important for many practical applications in aeronautics and beyond, particularly in the high Reynolds number regime. The present formulation is based on Helmholtz velocity decomposition where the velocity is presented as the gradient of a potential plus a rotational component. Substituting in the continuity equation yields a Poisson equation for the potential which is solved with a zero normal derivative at solid surfaces. The momentum equation is used to update the rotational component with no slip/no penetration surface boundary conditions. The pressure is related to the potential function through a special relation which is a generalization of Bernoulli's law, with a viscous term included. Results of calculations for two- and three-dimensional problems prove that the present formulation is a valid approach, with some possible benefits compared to existing methods.

Advances in visual representation of molecular potentials.

PubMed

Du, Qi-Shi; Huang, Ri-Bo; Chou, Kuo-Chen

2010-06-01

The recent advances in visual representations of molecular properties in 3D space are summarized, and their applications in molecular modeling study and rational drug design are introduced. The visual representation methods provide us with detailed insights into protein-ligand interactions, and hence can play a major role in elucidating the structure or reactivity of a biomolecular system. Three newly developed computation and visualization methods for studying the physical and chemical properties of molecules are introduced, including their electrostatic potential, lipophilicity potential and excess chemical potential. The newest application examples of visual representations in structure-based rational drug are presented. The 3D electrostatic potentials, calculated using the empirical method (EM-ESP), in which the classical Coulomb equation and traditional atomic partial changes are discarded, are highly consistent with the results by the higher level quantum chemical method. The 3D lipophilicity potentials, computed by the heuristic molecular lipophilicity potential method based on the principles of quantum mechanics and statistical mechanics, are more accurate and reliable than those by using the traditional empirical methods. The 3D excess chemical potentials, derived by the reference interaction site model-hypernetted chain theory, provide a new tool for computational chemistry and molecular modeling. For structure-based drug design, the visual representations of molecular properties will play a significant role in practical applications. It is anticipated that the new advances in computational chemistry will stimulate the development of molecular modeling methods, further enriching the visual representation techniques for rational drug design, as well as other relevant fields in life science.

Liquid-fueled SOFC power sources for transportation

NASA Astrophysics Data System (ADS)

Myles, K. M.; Doshi, R.; Kumar, R.; Krumpelt, M.

Traditionally, fuel cells have been developed for space or stationary terrestrial applications. As the first commercial 200-kW systems were being introduced by ONSI and Fuji Electric, the potentially much larger, but also more challenging, application in transportation was beginning to be addressed. As a result, fuel cell-powered buses have been designed and built, and R&D programs for fuel cell-powered passenger cars have been initiated. The engineering challenge of eventually replacing the internal combustion engine in buses, trucks, and passenger cars with fuel cell systems is to achieve much higher power densities and much lower costs than obtainable in systems designed for stationary applications. At present, the leading fuel cell candidate for transportation applications is, without question, the polymer electrolyte fuel cell (PEFC). Offering ambient temperature start-up and the potential for a relatively high power density, the polymer technology has attracted the interest of automotive manufacturers worldwide. But the difficulties of fuel handling for the PEFC have led to a growing interest in exploring the prospects for solid oxide fuel cells (SOFCs) operating on liquid fuels for transportation applications. Solid oxide fuel cells are much more compatible with liquid fuels (methanol or other hydrocarbons) and are potentially capable of power densities high enough for vehicular use. Two SOFC options for such use are discussed in this report.

Applications of mid-infrared spectroscopy in the clinical laboratory setting.

PubMed

De Bruyne, Sander; Speeckaert, Marijn M; Delanghe, Joris R

2018-01-01

Fourier transform mid-infrared (MIR-FTIR) spectroscopy is a nondestructive, label-free, highly sensitive and specific technique that provides complete information on the chemical composition of biological samples. The technique both can offer fundamental structural information and serve as a quantitative analysis tool. Therefore, it has many potential applications in different fields of clinical laboratory science. Although considerable technological progress has been made to promote biomedical applications of this powerful analytical technique, most clinical laboratory analyses are based on spectroscopic measurements in the visible or ultraviolet (UV) spectrum and the potential role of FTIR spectroscopy still remains unexplored. In this review, we present some general principles of FTIR spectroscopy as a useful method to study molecules in specimens by MIR radiation together with a short overview of methods to interpret spectral data. We aim at illustrating the wide range of potential applications of the proposed technique in the clinical laboratory setting with a focus on its advantages and limitations and discussing the future directions. The reviewed applications of MIR spectroscopy include (1) quantification of clinical parameters in body fluids, (2) diagnosis and monitoring of cancer and other diseases by analysis of body fluids, cells, and tissues, (3) classification of clinically relevant microorganisms, and (4) analysis of kidney stones, nails, and faecal fat.

Use and application of gelatin as potential biodegradable packaging materials for food products.

PubMed

Nur Hanani, Z A; Roos, Y H; Kerry, J P

2014-11-01

The manufacture and potential application of biodegradable films for food application has gained increased interest as alternatives to conventional food packaging polymers due to the sustainable nature associated with their availability, broad and abundant source range, compostability, environmentally-friendly image, compatibility with foodstuffs and food application, etc. Gelatin is one such material and is a unique and popularly used hydrocolloid by the food industry today due to its inherent characteristics, thereby potentially offering a wide range of further and unique industrial applications. Gelatin from different sources have different physical and chemical properties as they contain different amino acid contents which are responsible for the varying characteristics observed upon utilization in food systems and when being utilized more specifically, in the manufacture of films. Packaging films can be successfully produced from all gelatin sources and the behaviour and characteristics of gelatin-based films can be altered through the incorporation of other food ingredients to produce composite films possessing enhanced physical and mechanical properties. This review will present the current situation with respect to gelatin usage as a packaging source material and the challenges that remain in order to move the manufacture of gelatin-based films nearer to commercial reality. Copyright © 2014 Elsevier B.V. All rights reserved.

JPL - Small Power Systems Applications Project. [for solar thermal power plant development and commercialization

NASA Technical Reports Server (NTRS)

Ferber, R. R.; Marriott, A. T.; Truscello, V.

1978-01-01

The Small Power Systems Applications (SPSA) Project has been established to develop and commercialize small solar thermal power plants. The technologies of interest include all distributed and central receiver technologies which are potentially economically viable in power plant sizes of one to 10 MWe. The paper presents an overview of the SPSA Project and briefly discusses electric utility involvement in the Project.

SCADA Application for ACTS Technology

NASA Technical Reports Server (NTRS)

Fairbanks, Barry

1992-01-01

The results of a system level study done by Hughes Network Systems for NASA are presented. For the supervisory control and data acquisition (SCADA) application, use of Ka-band spot beam satellite technology associated with NASA's Advanced Communication Technology Satellite (ACTS) offers a reduction in Earth station antenna size and transmitter power that may translate into lower system costs. The approaches taken to determine commercial potential of the system are described.

Study 2.5 final report. DORCA computer program. Volume 4: Executive summary report

NASA Technical Reports Server (NTRS)

1972-01-01

The functions and capabilities of the Dynamic Operational Requirements and Cost Analysis Program are explained. The existence and purpose of the program are presented to provide an evaluation of program applicability to areas of responsibility for potential users. The implementation of the program on the Univac 1108 computer is discussed. The application of the program for mission planning and project management is described.

Medical Applications of Laser Induced Breakdown Spectroscopy

NASA Astrophysics Data System (ADS)

Pathak, A. K.; Rai, N. K.; Singh, Ankita; Rai, A. K.; Rai, Pradeep K.; Rai, Pramod K.

2014-11-01

Sedentary lifestyle of human beings has resulted in various diseases and in turn we require a potential tool that can be used to address various issues related to human health. Laser Induced Breakdown Spectroscopy (LIBS) is one such potential optical analytical tool that has become quite popular because of its distinctive features that include applicability to any type/phase of samples with almost no sample preparation. Several reports are available that discusses the capabilities of LIBS, suitable for various applications in different branches of science which cannot be addressed by traditional analytical methods but only few reports are available for the medical applications of LIBS. In the present work, LIBS has been implemented to understand the role of various elements in the formation of gallstones (formed under the empyema and mucocele state of gallbladder) samples along with patient history that were collected from Purvancal region of Uttar Pradesh, India. The occurrence statistics of gallstones under the present study reveal higher occurrence of gallstones in female patients. The gallstone occurrence was found more prevalent for those male patients who were having the habit of either tobacco chewing, smoking or drinking alcohols. This work further reports in-situ LIBS study of deciduous tooth and in-vivo LIBS study of human nail.

Nanotoxicology: the present and the future

EPA Science Inventory

Engineered nanomaterials, due to their unique properties, can enable novel applications, but at the same time raise concern about potential toxicity. The knowledge of nanotoxicology developed quickly in recent years on not only the biological effects of nanomaterials, but also on...

Crash data analyses for vehicle-to-infrastructure communications for safety applications.

DOT National Transportation Integrated Search

2012-11-01

This report presents the potential safety benefits of wireless communication between the roadway infrastructure and vehicles, : (i.e., vehicle-to-infrastructure (V2I) safety). Specifically, it identifies the magnitude, characteristics, and cost of cr...

Sample flow switching techniques on microfluidic chips.

PubMed

Pan, Yu-Jen; Lin, Jin-Jie; Luo, Win-Jet; Yang, Ruey-Jen

2006-02-15

This paper presents an experimental investigation into electrokinetically focused flow injection for bio-analytical applications. A novel microfluidic device for microfluidic sample handling is presented. The microfluidic chip is fabricated on glass substrates using conventional photolithographic and chemical etching processes and is bonded using a high-temperature fusion method. The proposed valve-less device is capable not only of directing a single sample flow to a specified output port, but also of driving multiple samples to separate outlet channels or even to a single outlet to facilitate sample mixing. The experimental results confirm that the sample flow can be electrokinetically pre-focused into a narrow stream and guided to the desired outlet port by means of a simple control voltage model. The microchip presented within this paper has considerable potential for use in a variety of applications, including high-throughput chemical analysis, cell fusion, fraction collection, sample mixing, and many other applications within the micro-total-analysis systems field.

Strategies towards an optimized use of the shallow geothermal potential

NASA Astrophysics Data System (ADS)

Schelenz, S.; Firmbach, L.; Kalbacher, T.; Goerke, U.; Kolditz, O.; Dietrich, P.; Vienken, T.

2013-12-01

Thermal use of the shallow subsurface for heat generation, cooling and thermal energy storage is increasingly gaining importance in reconsideration of future energy supplies, e.g. in the course of German energy transition, with application shifting from isolated to intensive use. The planning and dimensioning of (geo-)thermal applications is strongly influenced by the availability of exploration data. Hence, reliable site-specific dimensioning of systems for the thermal use of the shallow subsurface will contribute to an increase in resource efficiency, cost reduction during installation and operation, as well as reduction of environmental impacts and prevention of resource over-exploitation. Despite large cumulative investments that are being made for the utilization of the shallow thermal potential, thermal energy is in many cases exploited without prior on-site exploration and investigation of the local geothermal potential, due to the lack of adequate and cost-efficient exploration techniques. We will present new strategies for an optimized utilization of urban thermal potential, showcased at a currently developed residential neighborhood with high demand for shallow geothermal applications, based on a) enhanced site characterization and b) simulation of different site specific application scenarios. For enhanced site characterization, surface geophysics and vertical high resolution direct push-profiling were combined for reliable determination of aquifer structure and aquifer parameterization. Based on the site characterization, different site specific geothermal application scenarios, including different system types and system configurations, were simulated using OpenGeoSys to guarantee an environmental and economic sustainable thermal use of the shallow subsurface.

Advances in Electronic-Nose Technologies Developed for Biomedical Applications

PubMed Central

Wilson, Alphus D.; Baietto, Manuela

2011-01-01

The research and development of new electronic-nose applications in the biomedical field has accelerated at a phenomenal rate over the past 25 years. Many innovative e-nose technologies have provided solutions and applications to a wide variety of complex biomedical and healthcare problems. The purposes of this review are to present a comprehensive analysis of past and recent biomedical research findings and developments of electronic-nose sensor technologies, and to identify current and future potential e-nose applications that will continue to advance the effectiveness and efficiency of biomedical treatments and healthcare services for many years. An abundance of electronic-nose applications has been developed for a variety of healthcare sectors including diagnostics, immunology, pathology, patient recovery, pharmacology, physical therapy, physiology, preventative medicine, remote healthcare, and wound and graft healing. Specific biomedical e-nose applications range from uses in biochemical testing, blood-compatibility evaluations, disease diagnoses, and drug delivery to monitoring of metabolic levels, organ dysfunctions, and patient conditions through telemedicine. This paper summarizes the major electronic-nose technologies developed for healthcare and biomedical applications since the late 1980s when electronic aroma detection technologies were first recognized to be potentially useful in providing effective solutions to problems in the healthcare industry. PMID:22346620

The READY program: Building a global potential energy surface and reactive dynamic simulations for the hydrogen combustion.

PubMed

Mogo, César; Brandão, João

2014-06-30

READY (REActive DYnamics) is a program for studying reactive dynamic systems using a global potential energy surface (PES) built from previously existing PESs corresponding to each of the most important elementary reactions present in the system. We present an application to the combustion dynamics of a mixture of hydrogen and oxygen using accurate PESs for all the systems involving up to four oxygen and hydrogen atoms. Results at the temperature of 4000 K and pressure of 2 atm are presented and compared with model based on rate constants. Drawbacks and advantages of this approach are discussed and future directions of research are pointed out. Copyright © 2014 Wiley Periodicals, Inc.

Structural properties of liquid lanthanides using charge hard sphere reference system

NASA Astrophysics Data System (ADS)

Thakora, P. B.; Sonvane, Y. A.; Patel, H. P.; Gajjar, P. N.; Jani, A. R.

2012-06-01

In the present paper Charge Hard Sphere (CHS) system is employed to investigate the structural properties like long wavelength limit S(0), isothermal compressibility (χT) and coordination number n for some liquid lanthanides viz.: La, Ce, Pr, Nd, Eu, Gd, Tb, Dy, Ho, Er, Yb and Lu. Our well established parameter free model potential is used to describe the electron-ion interaction alongwith sarkar et al. dielectric function. From the present results, it is seen that good agreement between present results and available experimental data have been achieved. At last, we establish the applicability of our parameter free model potential and CHS method to account such structural properties.

What drives high flow events in the Swiss Alps? Recent developments in wavelet spectral analysis and their application to hydrology

NASA Astrophysics Data System (ADS)

Schaefli, B.; Maraun, D.; Holschneider, M.

2007-12-01

Extreme hydrological events are often triggered by exceptional co-variations of the relevant hydrometeorological processes and in particular by exceptional co-oscillations at various temporal scales. Wavelet and cross wavelet spectral analysis offers promising time-scale resolved analysis methods to detect and analyze such exceptional co-oscillations. This paper presents the state-of-the-art methods of wavelet spectral analysis, discusses related subtleties, potential pitfalls and recently developed solutions to overcome them and shows how wavelet spectral analysis, if combined to a rigorous significance test, can lead to reliable new insights into hydrometeorological processes for real-world applications. The presented methods are applied to detect potentially flood triggering situations in a high Alpine catchment for which a recent re-estimation of design floods encountered significant problems simulating the observed high flows. For this case study, wavelet spectral analysis of precipitation, temperature and discharge offers a powerful tool to help detecting potentially flood producing meteorological situations and to distinguish between different types of floods with respect to the prevailing critical hydrometeorological conditions. This opens very new perspectives for the analysis of model performances focusing on the occurrence and non-occurrence of different types of high flow events. Based on the obtained results, the paper summarizes important recommendations for future applications of wavelet spectral analysis in hydrology.

A kinesthetic-tactual display concept for helicopter-pilot workload reduction

NASA Technical Reports Server (NTRS)

Gilson, R. D.; Dunn, R. S.; Sun, P.

1977-01-01

A kinesthetic-tactual (K-T) display concept is now under research and development (R & D) at the Ohio State University. It appears to offer considerable promise for useful application in helicopters by conveying control information via the sense of touch. This is a review of the overall R & D program including the original K-T display design, initial studies in automobile and fixed-wing vehicles, and feasibility experiments in a helicopter simulator. In addition to investigations of control and potential workload reduction, present efforts are directed toward establishing optimal design requirements for K-T helicopter displays. Potential applications, modes of usage, and the kinds of information that may be displayed in helicopter applications are discussed along with a brief forecast of future R & D. A brief description of the latest multi-axis laboratory prototype K-T display is also provided.

The role of aviation technology in the Caribbean Basin

NASA Technical Reports Server (NTRS)

Smith, Robert W.

1988-01-01

Aviation technology can play a significant role in the development of the countries of the Caribbean Basin. A variety of applications of rotorcraft in the region, the benefits, both economic and political which can result from utilization of rotorcraft in both a public service and commercial role are presented. A computer simulation of rotorcraft used as emergency medical vehicles is applied to compare and evaluate the advantages of using rotorcraft technology such as civil derivatives of the new tiltrotor. It is concluded that by using a civil derivative of the tiltrotor, significant improvements can be obtained in the level of health service in the region. The potential for cargo and passenger transport applications are currently being investigated and a second computer simulation is being developed to be used to evaluate the potential benefits to be derived from such applications.

Analysis on the emission and potential application of Cherenkov radiation in boron neutron capture therapy: A Monte Carlo simulation study.

PubMed

Shu, Di-Yun; Geng, Chang-Ran; Tang, Xiao-Bin; Gong, Chun-Hui; Shao, Wen-Cheng; Ai, Yao

2018-07-01

This paper was aimed to explore the physics of Cherenkov radiation and its potential application in boron neutron capture therapy (BNCT). The Monte Carlo toolkit Geant4 was used to simulate the interaction between the epithermal neutron beam and the phantom containing boron-10. Results showed that Cherenkov photons can only be generated from secondary charged particles of gamma rays in BNCT, in which the 2.223 MeV prompt gamma rays are the main contributor. The number of Cherenkov photons per unit mass generated in the measurement region decreases linearly with the increase of boron concentration in both water and tissue phantom. The work presented the fundamental basis for applications of Cherenkov radiation in BNCT. Copyright © 2018 Elsevier Ltd. All rights reserved.

High- and Mid-temperature Superconducting Sensors for Far IR/Sub-mm Applications in Space

NASA Technical Reports Server (NTRS)

Lakew, Brook; Brasunas, J. C.

2004-01-01

In this review paper an overview of the potential applications of high Tc (approx. 90 K) superconductors (HTS) and mid-Tc (approx. 39 K) superconductors (MTS) thin films in far IR/Sub-mm thermal detectors is presented. HTSs (YBCO, GdBCO etc.) were discovered in the late 80s while superconductivity in MgB2, an MTS, was discovered in 2001. The sharp transition in transport properties of HTS has allowed the fabrication of composite infrared thermal detectors (bolometers) with better figures of merit than thermopile detectors - thermopiles are currently on board the CIRS instrument on the Cassini mission to Saturn. The potential for developing even more sensitive sensors for IR/Sub-mm applications using MgB2 thin films is assessed. Current MgB2 thin film deposition techniques and film quality are reviewed.

Applying a soft-robotic glove as assistive device and training tool with games to support hand function after stroke: Preliminary results on feasibility and potential clinical impact.

PubMed

Prange-Lasonder, Gerdienke B; Radder, Bob; Kottink, Anke I R; Melendez-Calderon, Alejandro; Buurke, Jaap H; Rietman, Johan S

2017-07-01

Recent technological developments regarding wearable soft-robotic devices extend beyond the current application of rehabilitation robotics and enable unobtrusive support of the arms and hands during daily activities. In this light, the HandinMind (HiM) system was developed, comprising a soft-robotic, grip supporting glove with an added computer gaming environment. The present study aims to gain first insight into the feasibility of clinical application of the HiM system and its potential impact. In order to do so, both the direct influence of the HiM system on hand function as assistive device and its therapeutic potential, of either assistive or therapeutic use, were explored. A pilot randomized clinical trial was combined with a cross-sectional measurement (comparing performance with and without glove) at baseline in 5 chronic stroke patients, to investigate both the direct assistive and potential therapeutic effects of the HiM system. Extended use of the soft-robotic glove as assistive device at home or with dedicated gaming exercises in a clinical setting was applicable and feasible. A positive assistive effect of the soft-robotic glove was proposed for pinch strength and functional task performance 'lifting full cans' in most of the five participants. A potential therapeutic impact was suggested with predominantly improved hand strength in both participants with assistive use, and faster functional task performance in both participants with therapeutic application.

Worldwide wind/diesel hybrid power system study: Potential applications and technical issues

NASA Astrophysics Data System (ADS)

King, W. R.; Johnson, B. L., III

1991-04-01

The world market potential for wind/diesel hybrid technology is a function of the need for electric power, the availability of sufficient wind resource to support wind/diesel power, and the existence of buyers with the financial means to invest in the technology. This study includes data related to each of these three factors. This study does not address market penetration, which would require analysis of application specific wind/diesel economics. Buyer purchase criteria, which are vital to assessing market penetration, are discussed only generally. Countries were screened for a country-specific market analysis based on indicators of need and wind resource. Both developed countries and less developed countries (LDCs) were screened for wind/diesel market potential. Based on the results of the screening, ten countries showing high market potential were selected for more extensive market analyses. These analyses provide country-specific market data to guide wind/diesel technology developers in making design decisions that will lead to a competitive product. Section 4 presents the country-specific data developed for these analyses, including more extensive wind resource characterization, application-specific market opportunities, business conditions, and energy market characterizations. An attempt was made to identify the potential buyers with ability to pay for wind/diesel technology required to meet the application-specific market opportunities identified for each country. Additionally, the country-specific data are extended to corollary opportunities in countries not covered by the study. Section 2 gives recommendations for wind/diesel research based on the findings of the study.

Potential for Imaging Engineered Tissues with X-Ray Phase Contrast

PubMed Central

Appel, Alyssa; Anastasio, Mark A.

2011-01-01

As the field of tissue engineering advances, it is crucial to develop imaging methods capable of providing detailed three-dimensional information on tissue structure. X-ray imaging techniques based on phase-contrast (PC) have great potential for a number of biomedical applications due to their ability to provide information about soft tissue structure without exogenous contrast agents. X-ray PC techniques retain the excellent spatial resolution, tissue penetration, and calcified tissue contrast of conventional X-ray techniques while providing drastically improved imaging of soft tissue and biomaterials. This suggests that X-ray PC techniques are very promising for evaluation of engineered tissues. In this review, four different implementations of X-ray PC imaging are described and applications to tissues of relevance to tissue engineering reviewed. In addition, recent applications of X-ray PC to the evaluation of biomaterial scaffolds and engineered tissues are presented and areas for further development and application of these techniques are discussed. Imaging techniques based on X-ray PC have significant potential for improving our ability to image and characterize engineered tissues, and their continued development and optimization could have significant impact on the field of tissue engineering. PMID:21682604

The potential of the fresh-water fern Azolla in aquatic farming systems

NASA Astrophysics Data System (ADS)

Bijl, Peter K.; Werf, vd, Adrie; Schluepmann, Henriette; Reichart, Gert-Jan; Brouwer, Paul; Nierop, Klaas G. J.; Hellgardt, Klaus; Brinkhuis, Henk

2014-05-01

With aquatic farming systems a new avenue in agriculture is explored, in which the competition with conventional arable land is avoided. The aquatic, ubiquitous, floating fern Azolla is not yet widely explored as potential crop in such farming systems, despite its high potential because it grows in many natural systems under low-light intensities, has an enormous annual yield, and has special biomass qualities for applications in food, feed and specialty chemical industries. But, what makes Azolla particularly interesting as cost-effective crop is its capability to take up atmospheric nitrogen through symbiosis with nitrogen-fixing bacteria Anabaena azollae. This makes Azolla independent of nitrogen fertilization. In order to explore the potential of Azolla as a crop for a suite of applications, we have assembled a team of expertise: AZOFAST, consisting of agricultural engineers, plant physiologists, chemical engineers and organic chemists. Our growth experiments reveal high annual production yields with constant harvest. We are developing a germination and spore collecting/preservation protocol as a first step to domestication. Finally we have explored the biomass quality of different species of extant Azolla. We performed organic chemical analyses on lipid and tannin extracts, and quantified yields of specific compounds within these fractions. In our presentation we will present some of our results to show the potential of Azolla as a new, sustainable aquatic crop serving all kinds of industrial streams from protein feed to platform chemicals.

The potential of expert systems for remote sensing application

NASA Technical Reports Server (NTRS)

Mooneyhan, D. W.

1983-01-01

An overview of the status and potential of artificial intelligence-driven expert systems in the role of image data analysis is presented. An expert system is defined and its structure is summarized. Three such systems designed for image interpretation are outlined. The use of an expert system to detect changes on the earth's surface is discussed, and the components of a knowledge-based image interpretation system and their make-up are outlined. An example of how such a system should work for an area in the tropics where deforestation has occurred is presented as a sequence of situation/action decisions.

Gas Chromatic Mass Spectrometer

NASA Technical Reports Server (NTRS)

Wey, Chowen

1995-01-01

Gas chromatograph/mass spectrometer (GC/MS) used to measure and identify combustion species present in trace concentration. Advanced extractive diagnostic method measures to parts per billion (PPB), as well as differentiates between different types of hydrocarbons. Applicable for petrochemical, waste incinerator, diesel transporation, and electric utility companies in accurately monitoring types of hydrocarbon emissions generated by fuel combustion, in order to meet stricter environmental requirements. Other potential applications include manufacturing processes requiring precise detection of toxic gaseous chemicals, biomedical applications requiring precise identification of accumulative gaseous species, and gas utility operations requiring high-sensitivity leak detection.

Potential uses of a wireless network in physical security systems.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Witzke, Edward L.

2010-07-01

Many possible applications requiring or benefiting from a wireless network are available for bolstering physical security and awareness at high security installations or facilities. These enhancements are not always straightforward and may require careful analysis, selection, tuning, and implementation of wireless technologies. In this paper, an introduction to wireless networks and the task of enhancing physical security is first given. Next, numerous applications of a wireless network are brought forth. The technical issues that arise when using a wireless network to support these applications are then discussed. Finally, a summary is presented.

Nimbus earth resources observations

NASA Technical Reports Server (NTRS)

Sabatini, R. R.; Rabchevsky, G. A.; Sissala, J. E.

1971-01-01

The potential for utilizing data gathered by Nimbus satellites to study the earth surface and its physical properties is illustrated. The Nimbus data applicable to investigations of the earth and its resources, and to the problems of resolution and cloud cover are described. Geological, hydrological, and oceanographic applications are discussed. Applications of the data to other fields, such as cartography, agriculture, forestry, and urban analysis are presented. Relevant information is also given on the Nimbus orbit and experiments; surface and atmospheric effects on HRIR and THIR radiation measurements; and noise problems in the AVCS, IDCS, HRIR, and THIR data.

TMS-EEG: From basic research to clinical applications

NASA Astrophysics Data System (ADS)

Hernandez-Pavon, Julio C.; Sarvas, Jukka; Ilmoniemi, Risto J.

2014-11-01

Transcranial magnetic stimulation (TMS) combined with electroencephalography (EEG) is a powerful technique for non-invasively studying cortical excitability and connectivity. The combination of TMS and EEG has widely been used to perform basic research and recently has gained importance in different clinical applications. In this paper, we will describe the physical and biological principles of TMS-EEG and different applications in basic research and clinical applications. We will present methods based on independent component analysis (ICA) for studying the TMS-evoked EEG responses. These methods have the capability to remove and suppress large artifacts, making it feasible, for instance, to study language areas with TMS-EEG. We will discuss the different applications and limitations of TMS and TMS-EEG in clinical applications. Potential applications of TMS are presented, for instance in neurosurgical planning, depression and other neurological disorders. Advantages and disadvantages of TMS-EEG and its variants such as repetitive TMS (rTMS) are discussed in comparison to other brain stimulation and neuroimaging techniques. Finally, challenges that researchers face when using this technique will be summarized.

Graph Theory and Brain Connectivity in Alzheimer's Disease.

PubMed

delEtoile, Jon; Adeli, Hojjat

2017-04-01

This article presents a review of recent advances in neuroscience research in the specific area of brain connectivity as a potential biomarker of Alzheimer's disease with a focus on the application of graph theory. The review will begin with a brief overview of connectivity and graph theory. Then resent advances in connectivity as a biomarker for Alzheimer's disease will be presented and analyzed.

Bayesian aggregation versus majority vote in the characterization of non-specific arm pain based on quantitative needle electromyography

PubMed Central

2010-01-01

Background Methods for the calculation and application of quantitative electromyographic (EMG) statistics for the characterization of EMG data detected from forearm muscles of individuals with and without pain associated with repetitive strain injury are presented. Methods A classification procedure using a multi-stage application of Bayesian inference is presented that characterizes a set of motor unit potentials acquired using needle electromyography. The utility of this technique in characterizing EMG data obtained from both normal individuals and those presenting with symptoms of "non-specific arm pain" is explored and validated. The efficacy of the Bayesian technique is compared with simple voting methods. Results The aggregate Bayesian classifier presented is found to perform with accuracy equivalent to that of majority voting on the test data, with an overall accuracy greater than 0.85. Theoretical foundations of the technique are discussed, and are related to the observations found. Conclusions Aggregation of motor unit potential conditional probability distributions estimated using quantitative electromyographic analysis, may be successfully used to perform electrodiagnostic characterization of "non-specific arm pain." It is expected that these techniques will also be able to be applied to other types of electrodiagnostic data. PMID:20156353

GOM-Face: GKP, EOG, and EMG-based multimodal interface with application to humanoid robot control.

PubMed

Nam, Yunjun; Koo, Bonkon; Cichocki, Andrzej; Choi, Seungjin

2014-02-01

We present a novel human-machine interface, called GOM-Face , and its application to humanoid robot control. The GOM-Face bases its interfacing on three electric potentials measured on the face: 1) glossokinetic potential (GKP), which involves the tongue movement; 2) electrooculogram (EOG), which involves the eye movement; 3) electromyogram, which involves the teeth clenching. Each potential has been individually used for assistive interfacing to provide persons with limb motor disabilities or even complete quadriplegia an alternative communication channel. However, to the best of our knowledge, GOM-Face is the first interface that exploits all these potentials together. We resolved the interference between GKP and EOG by extracting discriminative features from two covariance matrices: a tongue-movement-only data matrix and eye-movement-only data matrix. With the feature extraction method, GOM-Face can detect four kinds of horizontal tongue or eye movements with an accuracy of 86.7% within 2.77 s. We demonstrated the applicability of the GOM-Face to humanoid robot control: users were able to communicate with the robot by selecting from a predefined menu using the eye and tongue movements.

Electric Potential and Electric Field Imaging with Dynamic Applications: 2017 Research Award Innovation

NASA Technical Reports Server (NTRS)

Generazio, Ed

2017-01-01

The technology and methods for remote quantitative imaging of electrostatic potentials and electrostatic fields in and around objects and in free space is presented. Electric field imaging (EFI) technology may be applied to characterize intrinsic or existing electric potentials and electric fields, or an externally generated electrostatic field may be used for illuminating volumes to be inspected with EFI. The baseline sensor technology (e-Sensor) and its construction, optional electric field generation (quasi-static generator), and current e- Sensor enhancements (ephemeral e-Sensor) are discussed. Critical design elements of current linear and real-time two-dimensional (2D) measurement systems are highlighted, and the development of a three dimensional (3D) EFI system is presented. Demonstrations for structural, electronic, human, and memory applications are shown. Recent work demonstrates that phonons may be used to create and annihilate electric dipoles within structures. Phonon induced dipoles are ephemeral and their polarization, strength, and location may be quantitatively characterized by EFI providing a new subsurface Phonon-EFI imaging technology. Initial results from real-time imaging of combustion and ion flow, and their measurement complications, will be discussed. These new EFI capabilities are demonstrated to characterize electric charge distribution creating a new field of study embracing areas of interest including electrostatic discharge (ESD) mitigation, crime scene forensics, design and materials selection for advanced sensors, combustion science, on-orbit space potential, container inspection, remote characterization of electronic circuits and level of activation, dielectric morphology of structures, tether integrity, organic molecular memory, atmospheric science, and medical diagnostic and treatment efficacy applications such as cardiac polarization wave propagation and electromyography imaging.

Clinical applications of hallucinogens: A review.

PubMed

Garcia-Romeu, Albert; Kersgaard, Brennan; Addy, Peter H

2016-08-01

Hallucinogens fall into several different classes, as broadly defined by pharmacological mechanism of action, and chemical structure. These include psychedelics, entactogens, dissociatives, and other atypical hallucinogens. Although these classes do not share a common primary mechanism of action, they do exhibit important similarities in their ability to occasion temporary but profound alterations of consciousness, involving acute changes in somatic, perceptual, cognitive, and affective processes. Such effects likely contribute to their recreational use. However, a growing body of evidence indicates that these drugs may have therapeutic applications beyond their potential for abuse. This review will present data on several classes of hallucinogens with a particular focus on psychedelics, entactogens, and dissociatives, for which clinical utility has been most extensively documented. Information on each class is presented in turn, tracing relevant historical insights, highlighting similarities and differences between the classes from the molecular to the behavioral level, and presenting the most up-to-date information on clinically oriented research with these substances, with important ramifications for their potential therapeutic value. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Thermionic/AMTEC cascade converter concept for high-efficiency space power

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hagan, T.H. van; Smith, J.N. Jr.; Schuller, M.

1996-12-31

This paper presents trade studies that address the use of the thermionic/AMTEC cell--a cascaded, high-efficiency, static power conversion concept that appears well-suited to space power applications. Both the thermionic and AMTEC power conversion approaches have been shown to be promising candidates for space power. Thermionics offers system compactness via modest efficiency at high heat rejection temperatures, and AMTEC offers high efficiency at modest heat rejection temperature. From a thermal viewpoint the two are ideally suited for cascaded power conversion: thermionic heat rejection and AMTEC heat source temperatures are essentially the same. In addition to realizing conversion efficiencies potentially as highmore » as 35--40%, such a cascade offers the following perceived benefits: survivability; simplicity; technology readiness; and technology growth. Mechanical approaches and thermal/electric matching criteria for integrating thermionics and AMTEC into a single conversion device are described. Focusing primarily on solar thermal space power applications, parametric trends are presented to show the performance and cost potential that should be achievable with present-day technology in cascaded thermionic/AMTEC systems.« less

OhioView: Distribution of Remote Sensing Data Across Geographically Distributed Environments

NASA Technical Reports Server (NTRS)

Ramos, Calvin T.

1998-01-01

Various issues associated with the distribution of remote sensing data across geographically distributed environments are presented in viewgraph form. Specific topics include: 1) NASA education program background; 2) High level architectures, technologies and applications; 3) LeRC internal architecture and role; 4) Potential GIBN interconnect; 5) Potential areas of network investigation and research; 6) Draft of OhioView data model; and 7) the LeRC strategy and roadmap.

Selenium biomineralization for biotechnological applications.

PubMed

Nancharaiah, Yarlagadda V; Lens, Piet N L

2015-06-01

Selenium (Se) is not only a strategic element in high-tech electronics and an essential trace element in living organisms, but also a potential toxin with low threshold concentrations. Environmental biotechnological applications using bacterial biomineralization have the potential not only to remove selenium from contaminated waters, but also to sequester it in a reusable form. Selenium biomineralization has been observed in phylogenetically diverse microorganisms isolated from pristine and contaminated environments, yet it is one of the most poorly understood biogeochemical processes. Microbial respiration of selenium is unique because the microbial cells are presented with both soluble (SeO(4)(2-) and SeO(3)(2-)) and insoluble (Se(0)) forms of selenium as terminal electron acceptor. Here, we highlight selenium biomineralization and the potential biotechnological uses for it in bioremediation and wastewater treatment. Copyright © 2015 Elsevier Ltd. All rights reserved.

Graphene electrochemistry: an overview of potential applications.

PubMed

Brownson, Dale A C; Banks, Craig E

2010-11-01

Graphene, a 2D nanomaterial that possesses spectacular physical, chemical and thermal properties, has caused immense excitement amongst scientists since its freestanding form was isolated in 2004. With research into graphene rife, it promises enhancements and vast applicability within many industrial aspects. Furthermore, graphene possesses a vast array of unique and highly desirable electrochemical properties, and it is this application that offers the most enthralling and spectacular journey. We present a review of the current literature concerning the electrochemical applications and advancements of graphene, starting with its use as a sensor substrate through to applications in energy production and storage, depicting the truly remarkable journey of a material that has just come of age.

Application of the string method to the study of critical nuclei in capillary condensation.

PubMed

Qiu, Chunyin; Qian, Tiezheng; Ren, Weiqing

2008-10-21

We adopt a continuum description for liquid-vapor phase transition in the framework of mean-field theory and use the string method to numerically investigate the critical nuclei for capillary condensation in a slit pore. This numerical approach allows us to determine the critical nuclei corresponding to saddle points of the grand potential function in which the chemical potential is given in the beginning. The string method locates the minimal energy path (MEP), which is the most probable transition pathway connecting two metastable/stable states in configuration space. From the MEP, the saddle point is determined and the corresponding energy barrier also obtained (for grand potential). Moreover, the MEP shows how the new phase (liquid) grows out of the old phase (vapor) along the most probable transition pathway, from the birth of a critical nucleus to its consequent expansion. Our calculations run from partial wetting to complete wetting with a variable strength of attractive wall potential. In the latter case, the string method presents a unified way for computing the critical nuclei, from film formation at solid surface to bulk condensation via liquid bridge. The present application of the string method to the numerical study of capillary condensation shows the great power of this method in evaluating the critical nuclei in various liquid-vapor phase transitions.

Phytotechnologies – Preventing Exposures, Improving Public Health

PubMed Central

Henry, Heather F.; Burken, Joel G.; Maier, Raina M.; Newman, Lee A.; Rock, Steven; Schnoor, Jerald L.; Suk, William A.

2014-01-01

Phytotechnologies have the potential to reduce the amount and/or toxicity of deleterious chemicals/agents, and thereby, prevent human exposures to hazardous substances. As such, phytotechnologies are a tool for primary prevention within the context of public health. Research advances demonstrate that phytotechnologies can be uniquely tailored for effective exposure prevention for a variety of applications. In addition to exposure prevention, phytotechnologists have advanced the use of plants as sensors to delineate environmental contaminants and potential exposures. The applications presented in this paper are at various stages of development and are presented in a framework to reflect how phytotechnologies can help meet basic public health needs for access to clean water, air, and food resources. As plant-based technologies can often be integrated into communities at minimal cost and with low infrastructure needs, their use in improving environmental quality can be applied broadly to minimize potential contaminant exposure. These natural treatment systems concurrently provide ecosystem services of notable value to communities and society. In the future, integration and coordination of phytotechnology activities with public health research will allow technology development that focuses on prevention of environmental exposures. Such an approach will lead to an important role of phytotechnologies in providing sustainable solutions to environmental exposure challenges that improve public health and potentially reduce the burden of disease. PMID:23819283

Nuclear Forensics and Radiochemistry: Radiation Detection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rundberg, Robert S.

Radiation detection is necessary for isotope identification and assay in nuclear forensic applications. The principles of operation of gas proportional counters, scintillation counters, germanium and silicon semiconductor counters will be presented. Methods for calibration and potential pitfalls in isotope quantification will be described.

Complete genome sequence of the haloalkaliphilic, hydrogen-producing bacterium Halanaerobium hydrogeniformans.

PubMed

Brown, Steven D; Begemann, Matthew B; Mormile, Melanie R; Wall, Judy D; Han, Cliff S; Goodwin, Lynne A; Pitluck, Samuel; Land, Miriam L; Hauser, Loren J; Elias, Dwayne A

2011-07-01

Halanaerobium hydrogenoformans is an alkaliphilic bacterium capable of biohydrogen production at pH 11 and 7% (wt/vol) salt. We present the 2.6-Mb genome sequence to provide insights into its physiology and potential for bioenergy applications.

Handbook of sensor technical characteristics

NASA Astrophysics Data System (ADS)

Tanner, S.

1982-07-01

Space and terrestrial applications remote sensor systems are described. Each sensor is presented separately. Information is included on its objectives, description, technical characteristics, data products obtained, data archives location, period of operation, and measurement and potential derived parameters. Each sensor is cross indexed.

Elucidating Water Contamination by Fracturing Fluids and Formation Waters from Gas Wells: Integrating Isotopic and Geochemical Tracers

EPA Pesticide Factsheets

The objective of this presentation is to evaluate the potential and applicability of different geochemical and isotopic tracers for tracing the impacts of fracturing fluids and co-produced waters on water resources.

The dynamic properties of sandwich structures based on metal-ceramic foams.

DOT National Transportation Integrated Search

2014-01-01

The present research program has studied the fracture properties of closed pore metal-ceramic foams for their potential applications as core systems in sandwich structures. The composite foams were created at Fireline, Inc. (Youngstown, OH) using the...

Handbook of sensor technical characteristics

NASA Technical Reports Server (NTRS)

Tanner, S.

1982-01-01

Space and terrestrial applications remote sensor systems are described. Each sensor is presented separately. Information is included on its objectives, description, technical characteristics, data products obtained, data archives location, period of operation, and measurement and potential derived parameters. Each sensor is cross indexed.

Bacteriophages for detection and control of bacterial pathogens in food and food-processing environment.

PubMed

Brovko, Lubov Y; Anany, Hany; Griffiths, Mansel W

2012-01-01

This chapter presents recent advances in bacteriophage research and their application in the area of food safety. Section 1 describes general facts on phage biology that are relevant to their application for control and detection of bacterial pathogens in food and environmental samples. Section 2 summarizes the recently acquired data on application of bacteriophages to control growth of bacterial pathogens and spoilage organisms in food and food-processing environment. Section 3 deals with application of bacteriophages for detection and identification of bacterial pathogens. Advantages of bacteriophage-based methods are presented and their shortcomings are discussed. The chapter is intended for food scientist and food product developers, and people in food inspection and health agencies with the ultimate goal to attract their attention to the new developing technology that has a tremendous potential in providing means for producing wholesome and safe food. Copyright © 2012 Elsevier Inc. All rights reserved.

Limiting factors for carbon based chemical double layer capacitors

NASA Technical Reports Server (NTRS)

Rose, M. Frank; Johnson, C.; Owens, T.; Stevens, B.

1993-01-01

The Chemical Double Layer (CDL) capacitor improves energy storage density dramatically when compared with conventional electrolytic capacitors. When compared to batteries, the CDL Capacitor is much less energy dense; however, the power density is orders of magnitude better. As a result, CDL-battery combinations present an interesting pulse power system with many potential applications. Due to the nature of the CDL it is inherently a low voltage device. The applications of the CDL can be tailored to auxiliary energy and burst mode storages which require fast charge/discharge cycles. Typical of the applications envisioned are power system backup, directed energy weapons concepts, electric automobiles, and electric actuators. In this paper, we will discuss some of the general characteristics of carbon-based CDL technology describing the structure, performance parameters, and methods of construction. Further, analytical and experimental results which define the state of the art are presented and described in terms of impact on applications.

A high-efficiency thermoelectric converter for space applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Metzger, J.D.; El-Genk, M.S.

1990-01-01

This paper presents a concept for using high-temperature superconducting materials in thermoelectric generators (SCTE) to produce electricity at conversion efficiencies approaching 50% of the Carrot efficiency. The SCTE generator is applicable to systems operating in temperature ranges of high-temperature superconducting materials and thus would be a low-grade converter. Operating in cryogenic temperature ranges provides the advantage of inherently increasing the limits of the Carrot efficiency. Potential applications are for systems operating in space where the ambient temperatures are in the cryogenic temperature range. The advantage of using high-temperature superconducting material in a thermoelectric converter is that it would significantly reducemore » or eliminate the Joule heating losses in a thermoelectric element. This paper investigates the system aspects and the material requirements of the SCTE converter concept, and presents a conceptual design and an application for a space power system.« less

A high-efficiency thermoelectric converter for space applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Metzger, J.D.; El-Genk, M.S.

1990-12-31

This paper presents a concept for using high-temperature superconducting materials in thermoelectric generators (SCTE) to produce electricity at conversion efficiencies approaching 50% of the Carrot efficiency. The SCTE generator is applicable to systems operating in temperature ranges of high-temperature superconducting materials and thus would be a low-grade converter. Operating in cryogenic temperature ranges provides the advantage of inherently increasing the limits of the Carrot efficiency. Potential applications are for systems operating in space where the ambient temperatures are in the cryogenic temperature range. The advantage of using high-temperature superconducting material in a thermoelectric converter is that it would significantly reducemore » or eliminate the Joule heating losses in a thermoelectric element. This paper investigates the system aspects and the material requirements of the SCTE converter concept, and presents a conceptual design and an application for a space power system.« less

Possible applications for municipal solid waste fly ash.

PubMed

Ferreira, C; Ribeiro, A; Ottosen, L

2003-01-31

The present study focuses on existing practices related to the reuse of Municipal Solid Waste (MSW) fly ash and identifies new potential uses. Nine possible applications were identified and grouped into four main categories: construction materials (cement, concrete, ceramics, glass and glass-ceramics); geotechnical applications (road pavement, embankments); "agriculture" (soil amendment); and, miscellaneous (sorbent, sludge conditioning). Each application is analysed in detail, including final-product technical characteristics, with a special emphasis on environmental impacts. A comparative analysis of the different options is performed, stressing the advantages but also the weaknesses of each option. This information is systemized in order to provide a framework for the selection of best technology and final products. The results presented here show new possibilities for this waste reuse in a short-term, in a wide range of fields, resulting in great advantages in waste minimization as well as resources conservation.

Direct application of Padé approximant for solving nonlinear differential equations.

PubMed

Vazquez-Leal, Hector; Benhammouda, Brahim; Filobello-Nino, Uriel; Sarmiento-Reyes, Arturo; Jimenez-Fernandez, Victor Manuel; Garcia-Gervacio, Jose Luis; Huerta-Chua, Jesus; Morales-Mendoza, Luis Javier; Gonzalez-Lee, Mario

2014-01-01

This work presents a direct procedure to apply Padé method to find approximate solutions for nonlinear differential equations. Moreover, we present some cases study showing the strength of the method to generate highly accurate rational approximate solutions compared to other semi-analytical methods. The type of tested nonlinear equations are: a highly nonlinear boundary value problem, a differential-algebraic oscillator problem, and an asymptotic problem. The high accurate handy approximations obtained by the direct application of Padé method shows the high potential if the proposed scheme to approximate a wide variety of problems. What is more, the direct application of the Padé approximant aids to avoid the previous application of an approximative method like Taylor series method, homotopy perturbation method, Adomian Decomposition method, homotopy analysis method, variational iteration method, among others, as tools to obtain a power series solutions to post-treat with the Padé approximant. 34L30.

Invertibility of retarded response functions for Laplace transformable potentials: Application to one-body reduced density matrix functional theory.

PubMed

Giesbertz, K J H

2015-08-07

A theorem for the invertibility of arbitrary response functions is presented under the following conditions: the time dependence of the potentials should be Laplace transformable and the initial state should be a ground state, though it might be degenerate. This theorem provides a rigorous foundation for all density-functional-like theories in the time-dependent linear response regime. Especially for time-dependent one-body reduced density matrix (1RDM) functional theory, this is an important step forward, since a solid foundation has currently been lacking. The theorem is equally valid for static response functions in the non-degenerate case, so can be used to characterize the uniqueness of the potential in the ground state version of the corresponding density-functional-like theory. Such a classification of the uniqueness of the non-local potential in ground state 1RDM functional theory has been lacking for decades. With the aid of presented invertibility theorem presented here, a complete classification of the non-uniqueness of the non-local potential in 1RDM functional theory can be given for the first time.

Dynamic torsional response analysis of mechanoluminescent paint and its application to non-contacting automotive torque transducers

NASA Astrophysics Data System (ADS)

Kim, Gi-Woo; Kim, Ji-Sik

2014-01-01

This paper presents the result of a preliminary experimental study on the dynamic torsional response analysis of mechanoluminescent (ML) paint for potential development as a new type of non-contacting torque transducer. The torsional torque applied to a transmission shaft is measured by sensing the ML intensity emitting from an ML paint coating a transmission shaft. This study provides the fundamental knowledge for the development of new non-contacting torque sensing technology based on the ML intensity detection. The proposed measurement principle appears to offer potential applications in automotive torque measurement systems, even though the loading rate-dependent characteristics of the ML intensity needs to be examined further.

An intelligent interactive visual database management system for Space Shuttle closeout image management

NASA Technical Reports Server (NTRS)

Ragusa, James M.; Orwig, Gary; Gilliam, Michael; Blacklock, David; Shaykhian, Ali

1994-01-01

Status is given of an applications investigation on the potential for using an expert system shell for classification and retrieval of high resolution, digital, color space shuttle closeout photography. This NASA funded activity has focused on the use of integrated information technologies to intelligently classify and retrieve still imagery from a large, electronically stored collection. A space shuttle processing problem is identified, a working prototype system is described, and commercial applications are identified. A conclusion reached is that the developed system has distinct advantages over the present manual system and cost efficiencies will result as the system is implemented. Further, commercial potential exists for this integrated technology.

Many-body formulation of carriers capture time in quantum dots applicable in device simulation codes

NASA Astrophysics Data System (ADS)

Vallone, Marco

2010-03-01

We present an application of Green's functions formalism to calculate in a simplified but rigorous way electrons and holes capture time in quantum dots in closed form as function of carrier density, levels confinement potential, and temperature. Carrier-carrier (Auger) scattering and single LO-phonon emission are both addressed accounting for dynamic effects of the potential screening in the single plasmon pole approximation of the dielectric function. Regarding the LO-phonons interaction, the formulation evidences the role of the dynamic screening from wetting-layer carriers in comparison with its static limit, describes the interplay between screening and Fermi band filling, and offers simple expressions for capture time, suitable for modeling implementation.

Use of indocyanine green angiography in microsurgical subinguinal varicocelectomy - lessons learned from our initial experience.

PubMed

Cho, Chak-Lam; Ho, Kwan-Lun; Chan, Wayne Kwun-Wai; Chu, Ringo Wing-Hong; Law, In-Chak

2017-01-01

Microsurgical subinguinal varicocelectomy (MSV) is generally considered the gold standard nowadays in view of the lower risk of complications and recurrence. To achieve complete ligation of veins while preserving testicular artery (TA) during the procedure remains challenging despite the application of high power optical magnification and micro-Doppler ultrasonography. The use of intraoperative indocyanine green angiography (ICGA) with infrared fluorescence operative micro-scope in MSV potentially lowers the incidence of TA injury and shortens the learning curve of nov-ice surgeons. We present our initial experience in the application of the technique in nine patients and explore the potential of the new adjunct. Copyright® by the International Brazilian Journal of Urology.

Nanomaterial-Based Plasmon-Enhanced Infrared Spectroscopy.

PubMed

Yang, Xiaoxia; Sun, Zhipei; Low, Tony; Hu, Hai; Guo, Xiangdong; García de Abajo, F Javier; Avouris, Phaedon; Dai, Qing

2018-05-01

Surface-enhanced infrared absorption (SEIRA) has attracted increasing attention due to the potential of infrared spectroscopy in applications such as molecular trace sensing of solids, polymers, and proteins, specifically fueled by recent substantial developments in infrared plasmonic materials and engineered nanostructures. Here, the significant progress achieved in the past decades is reviewed, along with the current state of the art of SEIRA. In particular, the plasmonic properties of a variety of nanomaterials are discussed (e.g., metals, semiconductors, and graphene) along with their use in the design of efficient SEIRA configurations. To conclude, perspectives on potential applications, including single-molecule detection and in vivo bioassays, are presented. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A synchronization method for wireless acquisition systems, application to brain computer interfaces.

PubMed

Foerster, M; Bonnet, S; van Langhenhove, A; Porcherot, J; Charvet, G

2013-01-01

A synchronization method for wireless acquisition systems has been developed and implemented on a wireless ECoG recording implant and on a wireless EEG recording helmet. The presented algorithm and hardware implementation allow the precise synchronization of several data streams from several sensor nodes for applications where timing is critical like in event-related potential (ERP) studies. The proposed method has been successfully applied to obtain visual evoked potentials and compared with a reference biosignal amplifier. The control over the exact sampling frequency allows reducing synchronization errors that will otherwise accumulate during a recording. The method is scalable to several sensor nodes communicating with a shared base station.

Fabrication of Ni-Ti-O nanotube arrays by anodization of NiTi alloy and their potential applications

PubMed Central

Hang, Ruiqiang; Liu, Yanlian; Zhao, Lingzhou; Gao, Ang; Bai, Long; Huang, Xiaobo; Zhang, Xiangyu; Tang, Bin; Chu, Paul K.

2014-01-01

Nickel-titanium-oxide (Ni-Ti-O) nanotube arrays (NTAs) prepared on nearly equiatomic NiTi alloy shall have broad application potential such as for energy storage and biomedicine, but their precise structure control is a great challenge because of the high content of alloying element of Ni, a non-valve metal that cannot form a compact electronic insulating passive layer when anodized. In the present work, we systemically investigated the influence of various anodization parameters on the formation and structure of Ni-Ti-O NTAs and their potential applications. Our results show that well controlled NTAs can be fabricated during relatively wide ranges of the anodization voltage (5–90 V), electrolyte temperature (10–50°C) and electrolyte NH4F content (0.025–0.8 wt%) but within a narrow window of the electrolyte H2O content (0.0–1.0 vol%). Through modulating these parameters, the Ni-Ti-O NTAs with different diameter (15–70 nm) and length (45–1320 nm) can be produced in a controlled manner. Regarding potential applications, the Ni-Ti-O NTAs may be used as electrodes for electrochemical energy storage and non-enzymic glucose detection, and may constitute nanoscaled biofunctional coating to improve the biological performance of NiTi based biomedical implants. PMID:25520180

Single-Walled Carbon Nanotubes Probed with Insulator-Based Dielectrophoresis

PubMed Central

2017-01-01

Single-walled carbon nanotubes (SWNTs) offer unique electrical and optical properties. Common synthesis processes yield SWNTs with large length polydispersity (several tens of nanometers up to centimeters) and heterogeneous electrical and optical properties. Applications often require suitable selection and purification. Dielectrophoresis is one manipulation method for separating SWNTs based on dielectric properties and geometry. Here, we present a study of surfactant and single-stranded DNA-wrapped SWNTs suspended in aqueous solutions manipulated by insulator-based dielectrophoresis (iDEP). This method allows us to manipulate SWNTs with the help of arrays of insulating posts in a microfluidic device around which electric field gradients are created by the application of an electric potential to the extremities of the device. Semiconducting SWNTs were imaged during dielectrophoretic manipulation with fluorescence microscopy making use of their fluorescence emission in the near IR. We demonstrate SWNT trapping at low-frequency alternating current (AC) electric fields with applied potentials not exceeding 1000 V. Interestingly, suspended SWNTs showed both positive and negative dielectrophoresis, which we attribute to their ζ potential and the suspension properties. Such behavior agrees with common theoretical models for nanoparticle dielectrophoresis. We further show that the measured ζ potentials and suspension properties are in excellent agreement with a numerical model predicting the trapping locations in the iDEP device. This study is fundamental for the future application of low-frequency AC iDEP for technological applications of SWNTs. PMID:29131586

Mobilizing Older Adults: Harnessing the Potential of Smart Home Technologies. Contribution of the IMIA Working Group on Smart Homes and Ambient Assisted Living.

PubMed

Demiris, G; Thompson, H J

2012-01-01

This paper highlights the potential of smart home applications to not only assess mobility determinants for older adults in the home environment but also provide the opportunity for tailored interventions. We present a theoretical framework for assessing mobility parameters and utilizing this information to enable behavior change based on the Health Belief Model. We discuss examples that showcase the potential of smart home systems to not only measure but also improve mobility for community dwelling older adults. Mobility is a complex construct that cannot be addressed with a single monitoring approach or a single intervention. Instead, tailored interventions that address specific needs and behaviors of individuals and take into consideration preferences of older adults and potentially their social network are needed to effectively enforce positive behavior change. Smart home systems have the ability to capture details of one's daily living that could otherwise not be easily obtained; however, such data repositories alone are not sufficient to improve clinical outcomes if appropriate mechanisms for data mining and analysis, as well as tailored response systems are not in place. Unleashing the potential of smart home applications to measure and improve mobility has the potential of transforming elder care and providing potentially cost-effective tools to support independence for older adults. A technologically driven smart home application can maximize its clinical relevance by pursuing interactive features that can lead to behavior change.

Impact of Saw Dust Application on the Distribution of Potentially Toxic Metals in Contaminated Soil.

PubMed

Awokunmi, Emmmanuel E

2017-12-01

The need to develop an approach for the reclamation of contaminated site using locally available agricultural waste has been considered. The present study investigated the application of sawdust as an effective amendment in the immobilization of potentially toxic metals (PTMs) by conducting a greenhouse experiment on soil collected from an automobile dumpsite. The amended and non-amended soil samples were analyzed for their physicochemical parameters and sequential extraction of PTMs. The results revealed that application of amendment had positive impact on the physicochemical parameters as organic matter content and cation exchange capacity increased from 12.1% to 12.8% and 16.4 to 16.8 meq/100 g respectively. However, the mobility and bioavalability of these metals was reduced as they were found to be distributed mostly in the non-exchangeable phase of soil. Therefore, application of sawdust successfully immobilized PTMs and could be applied for future studies in agricultural soil reclamation.

Quinoa starch: Structure, properties, and applications.

PubMed

Li, Guantian; Zhu, Fan

2018-02-01

Quinoa (Chenopodium quinoa Willd.) has gained popularity worldwide largely due to the attractive nutritional profile. It also has much potential for food security due to the great genetic diversity. Starch is the main component of quinoa grain and makes up to 70% of the dry matter. The starch plays a crucial role in functional properties of quinoa and related food products. The starch granules are rather small (∼1-3μm) with relatively low amylose contents as compared with most of the other starches. Quinoa amylopectin has significant amounts of short chains and super-long chains. These unique features have generated research interest in using the starch for food and other applications such as creating Pickering emulsions. This review summarizes the present knowledge of the isolation, composition, granular and molecular structures, physicochemical properties, modifications, and applications of quinoa starch. It becomes obvious that this starch has great potential for food and nonfood applications. Copyright © 2017 Elsevier Ltd. All rights reserved.

Porphyrin-Based Nanostructures for Photocatalytic Applications

PubMed Central

Chen, Yingzhi; Li, Aoxiang; Huang, Zheng-Hong; Wang, Lu-Ning; Kang, Feiyu

2016-01-01

Well-defined organic nanostructures with controllable size and morphology are increasingly exploited in optoelectronic devices. As promising building blocks, porphyrins have demonstrated great potentials in visible-light photocatalytic applications, because of their electrical, optical and catalytic properties. From this perspective, we have summarized the recent significant advances on the design and photocatalytic applications of porphyrin-based nanostructures. The rational strategies, such as texture or crystal modification and interfacial heterostructuring, are described. The applications of the porphyrin-based nanostructures in photocatalytic pollutant degradation and hydrogen evolution are presented. Finally, the ongoing challenges and opportunities for the future development of porphyrin nanostructures in high-quality nanodevices are also proposed. PMID:28344308

Magnetic hydrogel nanocomposites and composite nanoparticles--a review of recent patented works.

PubMed

Daniel-da-Silva, Ana L; Carvalho, Rui S; Trindade, Tito

2013-06-01

Magnetic hydrogel nanocomposites and composite nanoparticles form a class of soft materials with remote controllable properties that have attracted great attention due to their potential use in diverse applications. These include medical applications such as controlled drug delivery, clinical imaging and cancer hyperthermia and ecological applications as well, such as wastewater treatment. The present review provides an overview of the patents disclosed and research work developed in the last decade on magnetic hydrogel nanocomposites and magnetic hydrogel composite nanoparticles envisaging the above mentioned applications. In this context, recent patented advances on chemical methods for the preparation of bulk hydrogel nanocomposites and composite nanoparticles will be reviewed.

Bistable Mechanisms for Space Applications

PubMed Central

Zirbel, Shannon A.; Tolman, Kyler A.; Trease, Brian P.

2016-01-01

Compliant bistable mechanisms are monolithic devices with two stable equilibrium positions separated by an unstable equilibrium position. They show promise in space applications as nonexplosive release mechanisms in deployment systems, thereby eliminating friction and improving the reliability and precision of those mechanical devices. This paper presents both analytical and numerical models that are used to predict bistable behavior and can be used to create bistable mechanisms in materials not previously feasible for compliant mechanisms. Materials compatible with space applications are evaluated for use as bistable mechanisms and prototypes are fabricated in three different materials. Pin-puller and cutter release mechanisms are proposed as potential space applications. PMID:28030588

Application of predictive modelling techniques in industry: from food design up to risk assessment.

PubMed

Membré, Jeanne-Marie; Lambert, Ronald J W

2008-11-30

In this communication, examples of applications of predictive microbiology in industrial contexts (i.e. Nestlé and Unilever) are presented which cover a range of applications in food safety from formulation and process design to consumer safety risk assessment. A tailor-made, private expert system, developed to support safe product/process design assessment is introduced as an example of how predictive models can be deployed for use by non-experts. Its use in conjunction with other tools and software available in the public domain is discussed. Specific applications of predictive microbiology techniques are presented relating to investigations of either growth or limits to growth with respect to product formulation or process conditions. An example of a probabilistic exposure assessment model for chilled food application is provided and its potential added value as a food safety management tool in an industrial context is weighed against its disadvantages. The role of predictive microbiology in the suite of tools available to food industry and some of its advantages and constraints are discussed.

Development and Application of the Collaborative Optimization Architecture in a Multidisciplinary Design Environment

NASA Technical Reports Server (NTRS)

Braun, R. D.; Kroo, I. M.

1995-01-01

Collaborative optimization is a design architecture applicable in any multidisciplinary analysis environment but specifically intended for large-scale distributed analysis applications. In this approach, a complex problem is hierarchically de- composed along disciplinary boundaries into a number of subproblems which are brought into multidisciplinary agreement by a system-level coordination process. When applied to problems in a multidisciplinary design environment, this scheme has several advantages over traditional solution strategies. These advantageous features include reducing the amount of information transferred between disciplines, the removal of large iteration-loops, allowing the use of different subspace optimizers among the various analysis groups, an analysis framework which is easily parallelized and can operate on heterogenous equipment, and a structural framework that is well-suited for conventional disciplinary organizations. In this article, the collaborative architecture is developed and its mathematical foundation is presented. An example application is also presented which highlights the potential of this method for use in large-scale design applications.

MSFC Skylab Apollo Telescope Mount. [a technical history and management critique

NASA Technical Reports Server (NTRS)

Morse, A. R.

1974-01-01

A technical history and management critique of the Skylab Apollo Telescope Mount (ATM) from initial conception through the design, manufacturing, testing and prelaunch phases is presented. A mission performance summary provides a general overview of the ATM's achievements in relationship to its design goals. Recommendations and conclusions applicable to hardware design, test program philosophy and performance, and program management techniques for the ATM with potential application to future programs are also discussed.

Pseudopotential Method for Higher Partial Wave Scattering

DOE Office of Scientific and Technical Information (OSTI.GOV)

Idziaszek, Zbigniew; Centrum Fizyki Teoretycznej, Polska Akademia Nauk, 02-668 Warsaw; Calarco, Tommaso

2006-01-13

We present a zero-range pseudopotential applicable for all partial wave interactions between neutral atoms. For p and d waves, we derive effective pseudopotentials, which are useful for problems involving anisotropic external potentials. Finally, we consider two nontrivial applications of the p-wave pseudopotential: we solve analytically the problem of two interacting spin-polarized fermions confined in a harmonic trap, and we analyze the scattering of p-wave interacting particles in a quasi-two-dimensional system.

Steganography: Past, Present, Future

DOE Office of Scientific and Technical Information (OSTI.GOV)

Judge, J C

Steganography (a rough Greek translation of the term Steganography is secret writing) has been used in various forms for 2500 years. It has found use in variously in military, diplomatic, personal and intellectual property applications. Briefly stated, steganography is the term applied to any number of processes that will hide a message within an object, where the hidden message will not be apparent to an observer. This paper will explore steganography from its earliest instances through potential future application.

Alternative working fluids for unitary equipment: A research perspective

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baxter, V.D.

This paper deals with present and planned ORNL activities to characterize alternatives to R-22 for unitary heat pump and air-conditioning applications. Results of small-scale bread-board tests of potential alternatives R-32, R-134a, R-152a and R-143a are discussed. Portions of the AFEAS/DOE global warming impact study dealing with the unitary application are summarized. Methods for leak detection with the new refrigerants are discussed.

A new method for qualitative simulation of water resources systems: 2. Applications

NASA Astrophysics Data System (ADS)

Antunes, M. P.; Seixas, M. J.; Camara, A. S.; Pinheiro, M.

1987-11-01

SLIN (Simulação Linguistica) is a new method for qualitative dynamic simulation. As was presented previously (Camara et al., this issue), SLIN relies upon a categorical representation of variables which are manipulated by logical rules. Two applications to water resources systems are included to illustrate SLIN's potential usefulness: the environmental impact evaluation of a hydropower plant and the assessment of oil dispersion in the sea after a tanker wreck.

A breakthrough for experiencing and understanding simulated physics

NASA Technical Reports Server (NTRS)

Watson, Val

1988-01-01

The use of computer simulation in physics research is discussed, focusing on improvements to graphic workstations. Simulation capabilities and applications of enhanced visualization tools are outlined. The elements of an ideal computer simulation are presented and the potential for improving various simulation elements is examined. The interface between the human and the computer and simulation models are considered. Recommendations are made for changes in computer simulation practices and applications of simulation technology in education.

Application of Raman Spectroscopy for Nondestructive Evaluation of Composite Materials

NASA Technical Reports Server (NTRS)

Washer, Glenn A.; Brooks, Thomas M. B.; Saulsberry, Regor

2007-01-01

This paper will present an overview of efforts to investigate the application of Raman spectroscopy for the characterization of Kevlar materials. Raman spectroscopy is a laser technique that is sensitive to molecular interactions in materials such as Kevlar, graphite and carbon used in composite materials. The overall goal of this research reported here is to evaluate Raman spectroscopy as a potential nondestructive evaluation (NDE) tool for the detection of stress rupture in Kevlar composite over-wrapped pressure vessels (COPVs). Characterization of the Raman spectra of Kevlar yarn and strands will be presented and compared with analytical models provided in the literature. Results of testing to investigate the effects of creep and high-temperature aging on the Raman spectra will be presented.

Sulfated Seaweed Polysaccharides as Multifunctional Materials in Drug Delivery Applications

PubMed Central

Cunha, Ludmylla; Grenha, Ana

2016-01-01

In the last decades, the discovery of metabolites from marine resources showing biological activity has increased significantly. Among marine resources, seaweed is a valuable source of structurally diverse bioactive compounds. The cell walls of marine algae are rich in sulfated polysaccharides, including carrageenan in red algae, ulvan in green algae and fucoidan in brown algae. Sulfated polysaccharides have been increasingly studied over the years in the pharmaceutical field, given their potential usefulness in applications such as the design of drug delivery systems. The purpose of this review is to discuss potential applications of these polymers in drug delivery systems, with a focus on carrageenan, ulvan and fucoidan. General information regarding structure, extraction process and physicochemical properties is presented, along with a brief reference to reported biological activities. For each material, specific applications under the scope of drug delivery are described, addressing in privileged manner particulate carriers, as well as hydrogels and beads. A final section approaches the application of sulfated polysaccharides in targeted drug delivery, focusing with particular interest the capacity for macrophage targeting. PMID:26927134

Biomedical Applications of Carbon Nanotubes: A Critical Review.

PubMed

Sharma, Priyanka; Mehra, Neelesh Kumar; Jain, Keerti; Jain, N K

2016-08-01

The convergence of nano and biotechnology is enabling scientific and technical knowledge for improving human well being. Carbon nanotubes have become most fascinating material to be studied and unveil new avenues in the field of nanobiotechnology. The nanometer size and high aspect ratio of the CNTs are the two distinct features, which have contributed to diverse biomedical applications. They have captured the attention as nanoscale materials due to their nanometric structure and remarkable list of superlative and extravagant properties that encouraged their exploitation for promising applications. Significant progress has been made in order to overcome some of the major hurdles towards biomedical application of nanomaterials, especially on issues regarding the aqueous solubility/dispersion and safety of CNTs. Functionalized CNTs have been used in drug targeting, imaging, and in the efficient delivery of gene and nucleic acids. CNTs have also demonstrated great potential in diverse biomedical uses like drug targeting, imaging, cancer treatment, tissue regeneration, diagnostics, biosensing, genetic engineering and so forth. The present review highlights the possible potential of CNTs in diagnostics, imaging and targeted delivery of bioactives and also outlines the future opportunities for biomedical applications.

MO-E-12A-01: Quantitative Imaging: Techniques, Applications, and Challenges

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackson, E; Jeraj, R; McNitt-Gray, M

The first symposium in the Quantitative Imaging Track focused on the introduction of quantitative imaging (QI) by illustrating the potential of QI in diagnostic and therapeutic applications in research and patient care, highlighting key challenges in implementation of such QI applications, and reviewing QI efforts of selected national and international agencies and organizations, including the FDA, NCI, NIST, and RSNA. This second QI symposium will focus more specifically on the techniques, applications, and challenges of QI. The first talk of the session will focus on modalityagnostic challenges of QI, beginning with challenges of the development and implementation of QI applicationsmore » in single-center, single-vendor settings and progressing to the challenges encountered in the most general setting of multi-center, multi-vendor settings. The subsequent three talks will focus on specific QI challenges and opportunities in the modalityspecific settings of CT, PET/CT, and MR. Each talk will provide information on modality-specific QI techniques, applications, and challenges, including current efforts focused on solutions to such challenges. Learning Objectives: Understand key general challenges of QI application development and implementation, regardless of modality. Understand selected QI techniques and applications in CT, PET/CT, and MR. Understand challenges, and potential solutions for such challenges, for the applications presented for each modality.« less

PET/MRI for Neurological Applications

PubMed Central

Catana, Ciprian; Drzezga, Alexander; Heiss, Wolf-Dieter; Rosen, Bruce R.

2013-01-01

PET and MRI provide complementary information in the study of the human brain. Simultaneous PET/MR data acquisition allows the spatial and temporal correlation of the measured signals, opening up opportunities impossible to realize using stand-alone instruments. This paper reviews the methodological improvements and potential neurological and psychiatric applications of this novel technology. We first present methods for improving the performance and information content of each modality by using the information provided by the other technique. On the PET side, we discuss methods that use the simultaneously acquired MR data to improve the PET data quantification. On the MR side, we present how improved PET quantification could be used to validate a number of MR techniques. Finally, we describe promising research, translational and clinical applications that could benefit from these advanced tools. PMID:23143086

DOE Office of Scientific and Technical Information (OSTI.GOV)

Buzzi, M.; Vaz, C. A. F.; Raabe, J.

Manipulating magnetisation by the application of an electric field in magnetoelectric multiferroics represents a timely issue due to the potential applications in low power electronics and the novel physics involved. Thanks to its element sensitivity and high spatial resolution, X-ray photoemission electron microscopy is a uniquely suited technique for the investigation of magnetoelectric coupling in multiferroic materials. In this work, we present a setup that allows for the application of in situ electric and magnetic fields while the sample is analysed in the microscope. As an example of the performances of the setup, we present measurements on Ni/Pb(Mg{sub 0.66}Nb{sub 0.33})O{submore » 3}-PbTiO{sub 3} and La{sub 0.7}Sr{sub 0.3}MnO{sub 3}/PMN-PT artificial multiferroic nanostructures.« less

[Application of photodynamic therapy in dentistry – literature review].

PubMed

Oruba, Zuzanna; Chomyszyn-Gajewska, Maria

Photodynamic therapy (PDT) is based on the principle that the target cells are destroyed by means of toxic reactive oxygen species generated upon the interaction of a photosensitizer, light and oxygen. This method is nowadays widely applied in various branches of medicine, mainly in oncology and dermatology. It is also applied in dentistry in the treatment of oral potentially malignant disorders (like lichen planus or leukoplakia) and infectious conditions (periodontitis, herpetic cheilitis, root canal disinfection). The application of the photodynamic therapy in the abovementioned indications is worth attention, as the method is noninvasive, painless, and the results of the published studies seem promising. The present article aims at presenting the principle of the photodynamic therapy and, based on the literature, the possibilities and results of its application in dentistry.

Transonic CFD applications at Boeing

NASA Technical Reports Server (NTRS)

Tinoco, E. N.

1989-01-01

The use of computational methods for three dimensional transonic flow design and analysis at the Boeing Company is presented. A range of computational tools consisting of production tools for every day use by project engineers, expert user tools for special applications by computational researchers, and an emerging tool which may see considerable use in the near future are described. These methods include full potential and Euler solvers, some coupled to three dimensional boundary layer analysis methods, for transonic flow analysis about nacelle, wing-body, wing-body-strut-nacelle, and complete aircraft configurations. As the examples presented show, such a toolbox of codes is necessary for the variety of applications typical of an industrial environment. Such a toolbox of codes makes possible aerodynamic advances not previously achievable in a timely manner, if at all.

Application of Satellite Based Augmentation Systems to Altitude Separation

NASA Astrophysics Data System (ADS)

Magny, Jean Pierre

This paper presents the application of GNSS1, or more precisely of Satellite Based Augmentation Systems (SBAS), to vertical separation for en-route, approach and landing operations. Potential improvements in terms of operational benefit and of safety are described for two main applications. First, vertical separation between en-route aircraft, which requires a system available across wide areas. SBAS (EGNOS, WAAS, and MSAS) are very well suited for this purpose before GNSS2 becomes available. And secondly, vertical separation from the ground during approach and landing, for which preliminary design principles of instrument approach procedures and safety issues are presented. Approach and landing phases are the subject of discussions within ICAO GNSS-P. En-route phases have been listed as GNSS-P future work and by RTCA for development of new equipments.

The extended Lennard-Jones potential energy function: A simpler model for direct-potential-fit analysis

NASA Astrophysics Data System (ADS)

Hajigeorgiou, Photos G.

2016-12-01

An analytical model for the diatomic potential energy function that was recently tested as a universal function (Hajigeorgiou, 2010) has been further modified and tested as a suitable model for direct-potential-fit analysis. Applications are presented for the ground electronic states of three diatomic molecules: oxygen, carbon monoxide, and hydrogen fluoride. The adjustable parameters of the extended Lennard-Jones potential model are determined through nonlinear regression by fits to calculated rovibrational energy term values or experimental spectroscopic line positions. The model is shown to lead to reliable, compact and simple representations for the potential energy functions of these systems and could therefore be classified as a suitable and attractive model for direct-potential-fit analysis.

Geographical Information System Model for Potential Mines Data Management Presentation in Kabupaten Gorontalo

NASA Astrophysics Data System (ADS)

Roviana, D.; Tajuddin, A.; Edi, S.

2017-03-01

Mining potential in Indonesian is very abundant, ranging from Sabang to Marauke. Kabupaten Gorontalo is one of many places in Indonesia that have different types of minerals and natural resources that can be found in every district. The abundant of mining potential must be balanced with good management and ease of getting information by investors. The current issue is, (1) ways of presenting data/information about potential mines area is still manually (the maps that already capture from satellite image, then printed and attached to information board in the office) it caused the difficulties of getting information; (2) the high cost of maps printing; (3) the difficulties of regency leader (bupati) to obtain information for strategic decision making about mining potential. The goal of this research is to build a model of Geographical Information System that could provide data management of potential mines, so that the investors could easily get information according to their needs. To achieve that goal Research and Development method is used. The result of this research, is a model of Geographical Information System that implemented in an application to presenting data management of mines.

Volunteer Services.

ERIC Educational Resources Information Center

Little (Arthur D.), Inc., Washington, DC.

This report presents important issues involved in the use of volunteers in the juvenile justice system. Chapter I discusses volunteer program designs, organizational structure, potential program applications, and public relations. Chapter II reviews the volunteer: who he is, his motives for volunteering, and suggestions for recruiting, screening,…

Automatic bio-sample bacteria detection system

NASA Technical Reports Server (NTRS)

Chappelle, E. W.; Colburn, M.; Kelbaugh, B. N.; Picciolo, G. L.

1971-01-01

Electromechanical device analyzes urine specimens in 15 minutes and processes one sample per minute. Instrument utilizes bioluminescent reaction between luciferase-luciferin mixture and adenosine triphosphate (ATP) to determine number of bacteria present in the sample. Device has potential application to analysis of other body fluids.

PESTICIDE TRANSFER EFFICIENCY FROM HOUSEHOLD SURFACES TO FOODS

EPA Science Inventory

Application of pesticides around homes presents a potential for exposure to young children. Contaminated surfaces can be contacted by children's hands or foods which could allow transfer of pesticides. The exposures caused by these contacts are uncertain because the amount of pes...

Forgotten Digital Tourniquet: Salvage of an Ischaemic Finger by Application of Medicinal Leeches

PubMed Central

Durrant, C; Townley, WA; Ramkumar, S; Khoo, CTK

2006-01-01

Individual finger tourniquets are appropriate to the management of a wide range of conditions presenting to an accident and emergency department. They are simpler and more comfortable to use than upper arm pneumatic tourniquets and commercially available digital tourniquets are not readily available in the accident and emergency unit. However, if a finger tourniquet is overlooked, ischaemia of the digit results, and gangrene may follow if the problem is not defused early enough, leading to potential disaster.1–3 We present one case where a digit was salvaged after 4 days of tourniquet application, using medicinal leeches. PMID:17002851

Monitoring photodynamic therapy with photoacoustic microscopy

NASA Astrophysics Data System (ADS)

Shao, Peng; Chapman, David W.; Moore, Ronald B.; Zemp, Roger J.

2015-10-01

We present our work on examining the feasibility of monitoring photodynamic therapy (PDT)-induced vasculature change with acoustic-resolution photoacoustic microscopy (PAM). Verteporfin, an FDA-approved photosensitizer for clinical PDT, was utilized. With a 60-μm-resolution PAM system, we demonstrated the capability of PAM to monitor PDT-induced vasculature variations in a chick chorioallantoic membrane model with topical application and in a rat ear with intravenous injection of the photosensitizer. We also showed oxygen saturation change in target blood vessels due to PDT. Success of the present approach may potentially lead to the application of PAM imaging in evaluating PDT efficacy, guiding treatment, and predicting responders from nonresponders.

High-power klystrons

NASA Astrophysics Data System (ADS)

Siambis, John G.; True, Richard B.; Symons, R. S.

1994-05-01

Novel emerging applications in advanced linear collider accelerators, ionospheric and atmospheric sensing and modification and a wide spectrum of industrial processing applications, have resulted in microwave tube requirements that call for further development of high power klystrons in the range from S-band to X-band. In the present paper we review recent progress in high power klystron development and discuss some of the issues and scaling laws for successful design. We also discuss recent progress in electron guns with potential grading electrodes for high voltage with short and long pulse operation via computer simulations obtained from the code DEMEOS, as well as preliminary experimental results. We present designs for high power beam collectors.

Precise 3D Track Reconstruction Algorithm for the ICARUS T600 Liquid Argon Time Projection Chamber Detector

DOE PAGES

Antonello, M.; Baibussinov, B.; Benetti, P.; ...

2013-01-15

Liquid Argon Time Projection Chamber (LAr TPC) detectors offer charged particle imaging capability with remarkable spatial resolution. Precise event reconstruction procedures are critical in order to fully exploit the potential of this technology. In this paper we present a new, general approach to 3D reconstruction for the LAr TPC with a practical application to the track reconstruction. The efficiency of the method is evaluated on a sample of simulated tracks. We present also the application of the method to the analysis of stopping particle tracks collected during the ICARUS T600 detector operation with the CNGS neutrino beam.

Application of RF-MEMS-Based Split Ring Resonators (SRRs) to the Implementation of Reconfigurable Stopband Filters: A Review

PubMed Central

Martín, Ferran; Bonache, Jordi

2014-01-01

In this review paper, several strategies for the implementation of reconfigurable split ring resonators (SRRs) based on RF-MEMS switches are presented. Essentially three types of RF-MEMS combined with split rings are considered: (i) bridge-type RF-MEMS on top of complementary split ring resonators CSRRs; (ii) cantilever-type RF-MEMS on top of SRRs; and (iii) cantilever-type RF-MEMS integrated with SRRs (or RF-MEMS SRRs). Advantages and limitations of these different configurations from the point of view of their potential applications for reconfigurable stopband filter design are discussed, and several prototype devices are presented. PMID:25474378

Computational fluid dynamics applications at McDonnel Douglas

NASA Technical Reports Server (NTRS)

Hakkinen, R. J.

1987-01-01

Representative examples are presented of applications and development of advanced Computational Fluid Dynamics (CFD) codes for aerodynamic design at the McDonnell Douglas Corporation (MDC). Transonic potential and Euler codes, interactively coupled with boundary layer computation, and solutions of slender-layer Navier-Stokes approximation are applied to aircraft wing/body calculations. An optimization procedure using evolution theory is described in the context of transonic wing design. Euler methods are presented for analysis of hypersonic configurations, and helicopter rotors in hover and forward flight. Several of these projects were accepted for access to the Numerical Aerodynamic Simulation (NAS) facility at the NASA-Ames Research Center.

Commercial applications and scientific research requirements for thermal-infrared observations of terrestrial surfaces

NASA Technical Reports Server (NTRS)

Goward, Samuel N.; Taranik, James V.; Laporte, Daniel; Putnam, Evelyn S. (Editor)

1986-01-01

In the spring of 1986 the EOSAT Company and NASA Headquarters organized a workshop to consider: (1) the potential value of space-acquired multiband thermal remote sensing in terrestrial research and commercial applications, and (2) the scientific and technological requirements for conducting such observations from the LANDSAT platform. The workshop defined the instrument characteristics of three types of sensors that would be needed to expand the use of thermal information for Earth observation and new commercial opportunities. The panels from two disciplines, geology and evapotranspiration/botany, along with the instrument panel, presented their recommendations to the workshop. The findings of these meetings are presented.

Removal of toxic metals and nonmetals from contaminated water.

PubMed

Bartzatt, R; Cano, M; Johnson, L; Nagel, D

1992-04-01

The effects of the application of potassium ferrate to remove possible toxic compounds are presented. Potassium ferrate (K2FeO4) is shown in this work to be an effective means to remove toxic metals and nonmetals from aqueous solution. The toxic material present in water is precipitated from aqueous solution and readily removed. Potassium ferrate removes itself from solution. Discolored contaminated water may be made clear by utilizing potassium ferrate. In addition, turbidities of solutions induced by dissolved substances are eliminated by the action of potassium ferrate. The efficacy of potassium ferrate in cleaning contaminated water shows great potential in application to municipal and industrial waste water.

Continuous monitoring of evapotranspiration (ET) overview of LSA-SAF evapotranspiration products

NASA Astrophysics Data System (ADS)

Arboleda, A.; Ghilain, N.; Gellens-Meulenberghs, F.

2017-10-01

Evapotranspiration (ET) is the flux of water between the surface (vegetation, soil and water bodies) and the atmosphere. Monitoring this water loss may be of crucial importance for applications in hydrology, agriculture, water use efficiency studies and drought monitoring. We introduce one of the few satellite-based operational evapotranspiration products, generated continuously and in near real-time over Europe, Africa and part of South America. The ET products (30 minutes and daily) are generated at the EUMETSAT's Satellite Application Facility on Land Surface Analysis (LSA-SAF) operations centre (http://landsaf.ipma.pt). Following our commitments to our user's community, we are continuously looking for new ways to improve the product. To accomplish this, the feedback from users and potential users of the products is of great interest. In this contribution we present the ET products characteristics and recent improvements gained thanks to the inclusion in our ET algorithm of new variables derived from Earth observation by MSG SEVIRI. We show examples of the ET products and we highlight their potential in droughts detection and monitoring. Some examples of possible applications are presented to invite users and researchers to explore the possibilities offered by LSA-SAF evapotranspiration products.

Imidazo[2,1-b]thiazoles and their use as pharmaceuticals: Sanofi-Aventis EP 1 923 062 A1 (equivalent to WO2008058641).

PubMed

Karimian, K

2009-03-01

Imidazothiazoles are well-known compounds and many derivatives of this fused ring system have been evaluated for potential biological activity. The present application is focused on imidazo[2,1-b]thiazoles with pharmacological ability to stimulate the expression (transcription) of the enzyme endothelial nitric oxide (NO) synthase. This invention contains two types of claims. First, several imidazo[2,1-b]thiazoles (and compositions thereof) that were not previously reported in chemical literature are claimed (claims 6 - 15). Second, the use of the claimed compounds in the treatment of several different diseases is claimed (claims 1 - 5 and 16). The claimed imidazo[2,1-b]thiazoles are synthesized by the condensation of 2-aminothiazole with an alpha-halo ketone. Evaluation of pharmacological activity of the claimed compounds is based on previously reported methodologies. Results are at their best reported in descriptive terms. The descriptive presentation of results in this application does not allow a critical evaluation of the claims. However, this does not diminish the potential commercial importance of this application. Because of the importance of nitric oxide regulation in physiological systems, more research in this area of medicinal chemistry can be anticipated.

First principles investigations of vinazene molecule and molecular crystal: a prospective candidate for organic photovoltaic applications.

PubMed

Mohamad, Mazmira; Ahmed, Rashid; Shaari, Amirudin; Goumri-Said, Souraya

2015-02-01

Escalating demand for sustainable energy resources, because of the rapid exhaustion of conventional energy resources as well as to maintain the environmental level of carbon dioxide (CO2) to avoid its adverse effect on the climate, has led to the exploitation of photovoltaic technology manifold more than ever. In this regard organic materials have attracted great attention on account of demonstrating their potential to harvest solar energy at an affordable rate for photovoltaic technology. 2-vinyl-4,5-dicyanoimidazole (vinazene) is considered as a suitable material over the fullerenes for photovoltaic applications because of its particular chemical and physical nature. In the present study, DFT approaches are employed to provide an exposition of optoelectronic properties of vinazene molecule and molecular crystal. To gain insight into its properties, different forms of exchange correlation energy functional/potential such as LDA, GGA, BLYP, and BL3YP are used. Calculated electronic structure of vinazene molecule has been displayed via HOMO-LUMO isosurfaces, whereas electronic structure of the vinazene molecular crystal, via electronic band structure, is presented. The calculated electronic and optical properties were analyzed and compared as well. Our results endorse vinazene as a suitable material for organic photovoltaic applications.

Model-based fault detection and isolation for intermittently active faults with application to motion-based thruster fault detection and isolation for spacecraft

NASA Technical Reports Server (NTRS)

Wilson, Edward (Inventor)

2008-01-01

The present invention is a method for detecting and isolating fault modes in a system having a model describing its behavior and regularly sampled measurements. The models are used to calculate past and present deviations from measurements that would result with no faults present, as well as with one or more potential fault modes present. Algorithms that calculate and store these deviations, along with memory of when said faults, if present, would have an effect on the said actual measurements, are used to detect when a fault is present. Related algorithms are used to exonerate false fault modes and finally to isolate the true fault mode. This invention is presented with application to detection and isolation of thruster faults for a thruster-controlled spacecraft. As a supporting aspect of the invention, a novel, effective, and efficient filtering method for estimating the derivative of a noisy signal is presented.

Capillary electrophoresis interfaced with a mass spectrometer (CE-MS): technical considerations and applicability for biomarker studies in animals.

PubMed

Albalat, Amaya; Husi, Holger; Siwy, Justyna; Nally, Jarlath E; McLauglin, Mark; Eckersall, Peter D; Mullen, William

2014-02-01

Proteomics is a growing field that has the potential to be applied to many biology-related disciplines. However, the study of the proteome has proven to be very challenging due to its high level of complexity when compared to genome and transcriptome data. In order to analyse this level of complexity, high resolution separation of peptides/proteins are needed together with high resolution analysers. Currently, liquid chromatography and capillary electrophoresis (CE) are the two most widely used separation techniques that can be coupled on-line with a mass spectrometer (MS). In CE, proteins/ peptides are separated according to their size, charge and shape leading to high resolving power. Although further progress in the area of sensitivity, throughput and proteome coverage are expected, MS-based proteomics have developed to a level at which they are habitually applied to study a wide range of biological questions. The aim of this review is to present CE-MS as a proteomic analytical platform for biomarker research that could be used in farm animal and veterinary studies. This is a MS-analytical platform that has been widely used for biomarker research in the biomedical field but its application in animal proteomic studies is relatively novel. The review will focus on introducing the CE-MS platform and the primary considerations for its application to biomarker research. Furthermore, current applications but more importantly potential application in the field of farm animals and veterinary science will be presented and discussed.

Teleradiology applications with DICOM-e-mail.

PubMed

Weisser, G; Engelmann, U; Ruggiero, S; Runa, A; Schröter, A; Baur, S; Walz, M

2007-05-01

For the connection of several partners to a Dicom-e-mail based teleradiology network concepts were developed to allow the integration of different teleradiology applications. The organisational and technical needs for such an integration were analysed. More than 60 institutions including 23 hospitals in the Rhein-Neckar-Region, Germany were connected. The needed functionality was grouped in six teleradiology applications (emergency consultation, tele-guided examinations, expert consultations, cooperative work, scientific cooperations and homework with on call services) and their technical and organisational needs according to availability, speed of transfer, workflow definitions and data security needs was analysed. For the local integration of teleradiology services the setup and workflow is presented for a standalone teleradiology workstation and a server based teleradiology gateway. The line type needed for different groups of applications and users is defined. The security concept and fallback strategies are laid out, potential security problems and sources of errors are discussed. The specialties for the emergency teleradiology application are presented. The DICOM-e-mail protocol is a flexible and powerful protocol that can be used for a variety of teleradiology applications. It can meet the conditions for emergency applications but is limited if synchronous applications like teleconferences are needed.

Complex Hollow Nanostructures: Synthesis and Energy-Related Applications.

PubMed

Yu, Le; Hu, Han; Wu, Hao Bin; Lou, Xiong Wen David

2017-04-01

Hollow nanostructures offer promising potential for advanced energy storage and conversion applications. In the past decade, considerable research efforts have been devoted to the design and synthesis of hollow nanostructures with high complexity by manipulating their geometric morphology, chemical composition, and building block and interior architecture to boost their electrochemical performance, fulfilling the increasing global demand for renewable and sustainable energy sources. In this Review, we present a comprehensive overview of the synthesis and energy-related applications of complex hollow nanostructures. After a brief classification, the design and synthesis of complex hollow nanostructures are described in detail, which include hierarchical hollow spheres, hierarchical tubular structures, hollow polyhedra, and multi-shelled hollow structures, as well as their hybrids with nanocarbon materials. Thereafter, we discuss their niche applications as electrode materials for lithium-ion batteries and hybrid supercapacitors, sulfur hosts for lithium-sulfur batteries, and electrocatalysts for oxygen- and hydrogen-involving energy conversion reactions. The potential superiorities of complex hollow nanostructures for these applications are particularly highlighted. Finally, we conclude this Review with urgent challenges and further research directions of complex hollow nanostructures for energy-related applications. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Biosurfactants: Promising Molecules for Petroleum Biotechnology Advances.

PubMed

De Almeida, Darne G; Soares Da Silva, Rita de Cássia F; Luna, Juliana M; Rufino, Raquel D; Santos, Valdemir A; Banat, Ibrahim M; Sarubbo, Leonie A

2016-01-01

The growing global demand for sustainable technologies that improves the efficiency of petrochemical processes in the oil industry has driven advances in petroleum biotechnology in recent years. Petroleum industry uses substantial amounts of petrochemical-based synthetic surfactants in its activities as mobilizing agents to increase the availability or recovery of hydrocarbons as well as many other applications related to extraction, treatment, cleaning, and transportation. However, biosurfactants have several potential applications for use across the oil processing chain and in the formulations of petrochemical products such as emulsifying/demulsifying agents, anticorrosive, biocides for sulfate-reducing bacteria, fuel formulation, extraction of bitumen from tar sands, and many other innovative applications. Due to their versatility and proven efficiency, biosurfactants are often presented as valuable versatile tools that can transform and modernize petroleum biotechnology in an attempt to provide a true picture of state of the art and directions or use in the oil industry. We believe that biosurfactants are going to have a significant role in many future applications in the oil industries and in this review therefore, we highlight recent important relevant applications, patents disclosures and potential future applications for biosurfactants in petroleum and related industries.

A review on nanomechanical resonators and their applications in sensors and molecular transportation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Arash, Behrouz; Rabczuk, Timon, E-mail: timon.rabczuk@uni-weimar.de; Jiang, Jin-Wu

2015-06-15

Nanotechnology has opened a new area in science and engineering, leading to the development of novel nano-electromechanical systems such as nanoresonators with ultra-high resonant frequencies. The ultra-high-frequency resonators facilitate wide-ranging applications such as ultra-high sensitive sensing, molecular transportation, molecular separation, high-frequency signal processing, and biological imaging. This paper reviews recent studies on dynamic characteristics of nanoresonators. A variety of theoretical approaches, i.e., continuum modeling, molecular simulations, and multiscale methods, in modeling of nanoresonators are reviewed. The potential application of nanoresonators in design of sensor devices and molecular transportation systems is introduced. The essence of nanoresonator sensors for detection of atomsmore » and molecules with vibration and wave propagation analyses is outlined. The sensitivity of the resonator sensors and their feasibility in detecting different atoms and molecules are particularly discussed. Furthermore, the applicability of molecular transportation using the propagation of mechanical waves in nanoresonators is presented. An extended application of the transportation methods for building nanofiltering systems with ultra-high selectivity is surveyed. The article aims to provide an up-to-date review on the mechanical properties and applications of nanoresonators, and inspire additional potential of the resonators.« less

Biosurfactants: Promising Molecules for Petroleum Biotechnology Advances

PubMed Central

De Almeida, Darne G.; Soares Da Silva, Rita de Cássia F.; Luna, Juliana M.; Rufino, Raquel D.; Santos, Valdemir A.; Banat, Ibrahim M.; Sarubbo, Leonie A.

2016-01-01

The growing global demand for sustainable technologies that improves the efficiency of petrochemical processes in the oil industry has driven advances in petroleum biotechnology in recent years. Petroleum industry uses substantial amounts of petrochemical-based synthetic surfactants in its activities as mobilizing agents to increase the availability or recovery of hydrocarbons as well as many other applications related to extraction, treatment, cleaning, and transportation. However, biosurfactants have several potential applications for use across the oil processing chain and in the formulations of petrochemical products such as emulsifying/demulsifying agents, anticorrosive, biocides for sulfate-reducing bacteria, fuel formulation, extraction of bitumen from tar sands, and many other innovative applications. Due to their versatility and proven efficiency, biosurfactants are often presented as valuable versatile tools that can transform and modernize petroleum biotechnology in an attempt to provide a true picture of state of the art and directions or use in the oil industry. We believe that biosurfactants are going to have a significant role in many future applications in the oil industries and in this review therefore, we highlight recent important relevant applications, patents disclosures and potential future applications for biosurfactants in petroleum and related industries. PMID:27843439

Monocrystalline CVD-diamond optics for high-power laser applications

NASA Astrophysics Data System (ADS)

Holly, C.; Traub, M.; Hoffmann, D.; Widmann, C.; Brink, D.; Nebel, C.; Gotthardt, T.; Sözbir, M. C.; Wenzel, C.

2016-03-01

The potential of diamond as an optical material for high-power laser applications in the wavelength regime from the visible spectrum (VIS) to the near infrared (NIR) is investigated. Single-crystal diamonds with lateral dimensions up to 7×7mm2 are grown with microwave plasma assisted chemical vapor deposition (MPACVD) in parallel with up to 60 substrates and are further processed to spherical optics for beam guidance and shaping. The synthetic diamonds offer superior thermal, mechanical and optical properties, including low birefringence, scattering and absorption, also around 1 μm wavelength. We present dielectric (AR and HR) coated single-crystal diamond optics which are tested under high laser power in the multi-kW regime. The thermally induced focal shift of the diamond substrates is compared to the focal shift of a standard collimating and focusing unit for laser cutting made of fused silica optics. Due to the high thermal conductivity and low absorption of the diamond substrates compared to the fused silica optics no additional focal shift caused by a thermally induced refractive index change in the diamond is observed in our experiments. We present experimental results regarding the performance of the diamond substrates with and without dielectric coatings under high power and the influences of growth induced birefringence on the optical quality. Finally, we discuss the potential of the presented diamond lenses for high-power applications in the field of laser materials processing.

Some experiences with the viscous-inviscid interaction approach

NASA Technical Reports Server (NTRS)

Vandalsem, W. R.; Steger, J. L.; Rao, K. V.

1987-01-01

Methods for simulating compressible viscous flow using the viscid-inviscid interaction approach are described. The formulations presented range from the more familiar full-potential/boundary-layer interaction schemes to a method for coupling Euler/Navier-Stokes and boundary-layer algorithms. An effort is made to describe the advantages and disadvantages of each formulation. Sample results are presented which illustrate the applicability of the methods.

Radiation transport codes for potential applications related to radiobiology and radiotherapy using protons, neutrons, and negatively charged pions

NASA Technical Reports Server (NTRS)

Armstrong, T. W.

1972-01-01

Several Monte Carlo radiation transport computer codes are used to predict quantities of interest in the fields of radiotherapy and radiobiology. The calculational methods are described and comparisions of calculated and experimental results are presented for dose distributions produced by protons, neutrons, and negatively charged pions. Comparisons of calculated and experimental cell survival probabilities are also presented.

Keeping Goliath on His Toes: A Case-Discussion Method for Increasing Engagement and Individual Accountability in Large Classes

ERIC Educational Resources Information Center

Harding, Lora Mitchell

2018-01-01

Application-based assignments are often forgone in large marketing classes because of the daunting implementation and assessment challenges they present. One solution is to divide large classes into groups, but groups present their own challenges--of note, the potential for students to free-ride on the efforts of others. The 4Ps method of case…

Civil tiltrotor missions and applications

NASA Technical Reports Server (NTRS)

Clay, Bill; Baumgaertner, Paul; Thompson, Pete; Meyer, Sam; Reber, Ron; Berry, Dennis (Editor)

1987-01-01

In 1983, an FAA-sponsored National Rotorcraft Program sought to identify improvements to the national interurban transportation networks and determined that conventional helicopters did not have the potential to satisfy requirements because of a lack of capacity, high operational costs, and high noise levels. Tiltrotors, it was felt offered a better potential to improve interurban air transport service. In 1985, the FAA proposed a joint civil tiltrotor study with NASA and DOD that would capitalize on development of the military V-22 tiltrotor and document the potential of the commercial tiltrotor transport market. The results of a study on the mission and application of a civil tiltrotor is presented. This study addresses national issues and includes a market summary. A technical summary provides information on six design configurations and potential risk areas are identified. The development of a National Plan for a tiltrotor transportation system is recommended including civil tiltrotor technology development, infrastructure planning and development, a flight technology demonstration plan, and near term actions.

Cloud Detection with the Earth Polychromatic Imaging Camera (EPIC)

NASA Technical Reports Server (NTRS)

Meyer, Kerry; Marshak, Alexander; Lyapustin, Alexei; Torres, Omar; Wang, Yugie

2011-01-01

The Earth Polychromatic Imaging Camera (EPIC) on board the Deep Space Climate Observatory (DSCOVR) would provide a unique opportunity for Earth and atmospheric research due not only to its Lagrange point sun-synchronous orbit, but also to the potential for synergistic use of spectral channels in both the UV and visible spectrum. As a prerequisite for most applications, the ability to detect the presence of clouds in a given field of view, known as cloud masking, is of utmost importance. It serves to determine both the potential for cloud contamination in clear-sky applications (e.g., land surface products and aerosol retrievals) and clear-sky contamination in cloud applications (e.g., cloud height and property retrievals). To this end, a preliminary cloud mask algorithm has been developed for EPIC that applies thresholds to reflected UV and visible radiances, as well as to reflected radiance ratios. This algorithm has been tested with simulated EPIC radiances over both land and ocean scenes, with satisfactory results. These test results, as well as algorithm sensitivity to potential instrument uncertainties, will be presented.

Planning guidelines for computerized transaxial tomography (CT)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1976-11-23

Guidelines to assist local communities in review and decisionmaking related to computerized tomography (CT) 'head' and 'whole body' scanner needs and placement are presented. Although medical benefits for head scanning are well established, the proper role of whole body scanning in relation to other diagnostic procedures has not been determined. It is recommended that a 20 percent weighted consideration could be given to a potential CT scanner applicant's present capabilities in diagnostic 'body' work. The following guidelines for CT are recommended for use in assessing work qualifications of potential CT scanner applicants: (1) The facility must have an active neurosurgicalmore » service, with a geographically full-time board - certified neurosurgeon and at least 50 intracranial procedures performed annually. (2) The facility must have an active neurological service, with a geographically full-time board - certified neurologist. (3) The facility must have on staff a qualified neuroradiologist. It is recommended that the CT scanner utilization level be a minimum of 3,000 examinations per year per unit of new equipment. The applicant must submit financial data and must be committed to providing care to all patients, independent of ability to pay. The applicant must submit letters from area hospitals agreeing to utilize the scanner services. Additional criteria are given for body scanning work and for the number of scanners in a specific area. Detailed information is presented about scanner development and use in southeastern Pennsylvania and neighboring planning areas, and the cost of scanner operations is compared with revenues. The CT scanner committee membership is included.« less

Application of adaptive antenna techniques to future commercial satellite communication

NASA Technical Reports Server (NTRS)

Ersoy, L.; Lee, E. A.; Matthews, E. W.

1987-01-01

The purpose of this contract was to identify the application of adaptive antenna technique in future operational commercial satellite communication systems and to quantify potential benefits. The contract consisted of two major subtasks. Task 1, Assessment of Future Commercial Satellite System Requirements, was generally referred to as the Adaptive section. Task 2 dealt with Pointing Error Compensation Study for a Multiple Scanning/Fixed Spot Beam Reflector Antenna System and was referred to as the reconfigurable system. Each of these tasks was further sub-divided into smaller subtasks. It should also be noted that the reconfigurable system is usually defined as an open-loop system while the adaptive system is a closed-loop system. The differences between the open- and closed-loop systems were defined. Both the adaptive and reconfigurable systems were explained and the potential applications of such systems were presented in the context of commercial communication satellite systems.

Application of adaptive antenna techniques to future commercial satellite communications. Executive summary

NASA Technical Reports Server (NTRS)

Ersoy, L.; Lee, E. A.; Matthews, E. W.

1987-01-01

The purpose of this contract was to identify the application of adaptive antenna technique in future operational commercial satellite communication systems and to quantify potential benefits. The contract consisted of two major subtasks. Task 1, Assessment of Future Commercial Satellite System Requirements, was generally referred to as the Adaptive section. Task 2 dealt with Pointing Error Compensation Study for a Multiple Scanning/Fixed Spot Beam Reflector Antenna System and was referred to as the reconfigurable system. Each of these tasks was further subdivided into smaller subtasks. It should also be noted that the reconfigurable system is usually defined as an open-loop system while the adaptive system is a closed-loop system. The differences between the open- and closed-loop systems were defined. Both the adaptive and reconfigurable systems were explained and the potential applications of such systems were presented in the context of commercial communication satellite systems.

Bioactive Compounds from Macroalgae in the New Millennium: Implications for Neurodegenerative Diseases

PubMed Central

Barbosa, Mariana; Valentão, Patrícia; Andrade, Paula B.

2014-01-01

Marine environment has proven to be a rich source of structurally diverse and complex compounds exhibiting numerous interesting biological effects. Macroalgae are currently being explored as novel and sustainable sources of bioactive compounds for both pharmaceutical and nutraceutical applications. Given the increasing prevalence of different forms of dementia, researchers have been focusing their attention on the discovery and development of new compounds from macroalgae for potential application in neuroprotection. Neuroprotection involves multiple and complex mechanisms, which are deeply related. Therefore, compounds exerting neuroprotective effects through different pathways could present viable approaches in the management of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s. In fact, several studies had already provided promising insights into the neuroprotective effects of a series of compounds isolated from different macroalgae species. This review will focus on compounds from macroalgae that exhibit neuroprotective effects and their potential application to treat and/or prevent neurodegenerative diseases. PMID:25257784

Bioactive compounds from macroalgae in the new millennium: implications for neurodegenerative diseases.

PubMed

Barbosa, Mariana; Valentão, Patrícia; Andrade, Paula B

2014-09-25

Marine environment has proven to be a rich source of structurally diverse and complex compounds exhibiting numerous interesting biological effects. Macroalgae are currently being explored as novel and sustainable sources of bioactive compounds for both pharmaceutical and nutraceutical applications. Given the increasing prevalence of different forms of dementia, researchers have been focusing their attention on the discovery and development of new compounds from macroalgae for potential application in neuroprotection. Neuroprotection involves multiple and complex mechanisms, which are deeply related. Therefore, compounds exerting neuroprotective effects through different pathways could present viable approaches in the management of neurodegenerative diseases, such as Alzheimer's and Parkinson's. In fact, several studies had already provided promising insights into the neuroprotective effects of a series of compounds isolated from different macroalgae species. This review will focus on compounds from macroalgae that exhibit neuroprotective effects and their potential application to treat and/or prevent neurodegenerative diseases.

Graphene oxide liquid crystals: synthesis, phase transition, rheological property, and applications in optoelectronics and display.

PubMed

Lin, Feng; Tong, Xin; Wang, Yanan; Bao, Jiming; Wang, Zhiming M

2015-12-01

Graphene oxide (GO) liquid crystals (LCs) are macroscopically ordered GO flakes dispersed in water or polar organic solvents. Since the first report in 2011, GO LCs have attracted considerable attention for their basic properties and potential device applications. In this review, we summarize recent developments and present a comprehensive understanding of GO LCs via many aspects ranging from the exfoliation of GO flakes from graphite, to phases and phase transitions under various conditions, the orientational responses of GO under external magnetic and electric fields, and finally Kerr effect and display applications. The emphasis is placed on the unique and basic properties of GO and their ordered assembly. We will also discuss challenges and issues that need to be overcome in order to gain a more fundamental understanding and exploit full device potentials of GO LCs.

Recycling carbon fibre reinforced polymers for structural applications: technology review and market outlook.

PubMed

Pimenta, Soraia; Pinho, Silvestre T

2011-02-01

Both environmental and economic factors have driven the development of recycling routes for the increasing amount of carbon fibre reinforced polymer (CFRP) waste generated. This paper presents a review of the current status and outlook of CFRP recycling operations, focusing on state-of-the-art fibre reclamation and re-manufacturing processes, and on the commercialisation and potential applications of recycled products. It is shown that several recycling and re-manufacturing processes are reaching a mature stage, with implementations at commercial scales in operation, production of recycled CFRPs having competitive structural performances, and demonstrator components having been manufactured. The major challenges for the sound establishment of a CFRP recycling industry and the development of markets for the recyclates are summarised; the potential for introducing recycled CFRPs in structural components is discussed, and likely promising applications are investigated. Copyright © 2010 Elsevier Ltd. All rights reserved.

Development of the infrared instrument for gas detection

NASA Astrophysics Data System (ADS)

Chen, Ching-Wei; Chen, Chia-Ray

2017-08-01

MWIR (Mid-Wave Infrared) spectroscopy shows a large potential in the current IR devices market, due to its multiple applications, such as gas detection, chemical analysis, industrial monitoring, combustion and flame characterization. It opens this technique to the fields of application, such as industrial monitoring and control, agriculture and environmental monitoring. However, a major barrier, which is the lack of affordable specific key elements such a MWIR light sources and low cost uncooled detectors, have held it back from its widespread use. In this paper an uncooled MWIR detector combined with image enhancement technique is reported. This investigation shows good results in gas leakage detection test. It also verify the functions of self-developed MWIR lens and optics. A good agreement in theoretical design and experiment give us the lessons learned for the potential application in infrared satellite technology. A brief discussions will also be presented in this paper.

Sports Ultrasound: Applications Beyond the Musculoskeletal System.

PubMed

Finnoff, Jonathan T; Ray, Jeremiah; Corrado, Gianmichael; Kerkhof, Deanna; Hill, John

2016-09-01

Traditionally, ultrasound has been used to evaluate musculoskeletal injuries in athletes; however, ultrasound applications extend well beyond musculoskeletal conditions, many of which are pertinent to athletes. Articles were identified in PubMed using the search terms ultrasound, echocardiogram, preparticipation physical examination, glycogen, focused assessment with sonography of trauma, optic nerve, and vocal cord dysfunction. No date restrictions were placed on the literature search. Clinical review. Level 4. Several potential applications of nonmusculoskeletal ultrasound in sports medicine are presented, including extended Focused Assessment with Sonography for Trauma (eFAST), limited echocardiographic screening during preparticipation physical examinations, assessment of muscle glycogen stores, optic nerve sheath diameter measurements in athletes with increased intracranial pressure, and assessment of vocal cord dysfunction in athletes. Ultrasound can potentially be used to assist athletes with monitoring their muscle glycogen stores and the diagnosis of multiple nonmusculoskeletal conditions within sports medicine. © 2016 The Author(s).

Application of laminar flow control to high-bypass-ratio turbofan engine nacelles

NASA Technical Reports Server (NTRS)

Wie, Y. S.; Collier, F. S., Jr.; Wagner, R. D.

1991-01-01

Recently, the concept of the application of hybrid laminar flow to modern commercial transport aircraft was successfully flight tested on a Boeing 757 aircraft. In this limited demonstration, in which only part of the upper surface of the swept wing was designed for the attainment of laminar flow, significant local drag reduction was measured. This paper addresses the potential application of this technology to laminarize the external surface of large, modern turbofan engine nacelles which may comprise as much as 5-10 percent of the total wetted area of future commercial transports. A hybrid-laminar-flow-control (HLFC) pressure distribution is specified and the corresponding nacelle geometry is computed utilizing a predictor/corrector design method. Linear stability calculations are conducted to provide predictions of the extent of the laminar boundary layer. Performance studies are presented to determine potential benefits in terms of reduced fuel consumption.

An Evaluation Tool for Agricultural Health and Safety Mobile Applications.

PubMed

Reyes, Iris; Ellis, Tammy; Yoder, Aaron; Keifer, Matthew C

2016-01-01

As the use of mobile devices and their software applications, or apps, becomes ubiquitous, use amongst agricultural working populations is expanding as well. The smart device paired with a well-designed app has potential for improving workplace health and safety in the hands of those who can act upon the information provided. Many apps designed to assess workplace hazards and implementation of worker protections already exist. However, the abundance and diversity of such applications also presents challenges regarding evaluation practices and assignation of value. This is particularly true in the agricultural workspace, as there is currently little information on the value of these apps for agricultural safety and health. This project proposes a framework for developing and evaluating apps that have potential usefulness in agricultural health and safety. The evaluation framework is easily transferable, with little modification for evaluation of apps in several agriculture-specific areas.

Status and applications of diamond and diamond-like materials: An emerging technology

NASA Technical Reports Server (NTRS)

1990-01-01

Recent discoveries that make possible the growth of crystalline diamond by chemical vapor deposition offer the potential for a wide variety of new applications. This report takes a broad look at the state of the technology following from these discoveries in relation to other allied materials, such as high-pressure diamond and cubic boron nitride. Most of the potential defense, space, and commercial applications are related to diamond's hardness, but some utilize other aspects such as optical or electronic properties. The growth processes are reviewed, and techniques for characterizing the resulting materials' properties are discussed. Crystalline diamond is emphasized, but other diamond-like materials (silicon carbide, amorphous carbon containing hydrogen) are also examined. Scientific, technical, and economic problem areas that could impede the rapid exploitation of these materials are identified. Recommendations are presented covering broad areas of research and development.

The future is 'ambient'

NASA Astrophysics Data System (ADS)

Lugmayr, Artur

2006-02-01

The research field of ambient media starts to spread rapidly and first applications for consumer homes are on the way. Ambient media is the logical continuation of research around media. Media has been evolving from old media (e.g. print media), to integrated presentation in one form (multimedia - or new media), to generating a synthetic world (virtual reality), to the natural environment is the user-interface (ambient media), and will be evolving towards real/synthetic undistinguishable media (bio-media or bio-multimedia). After the IT bubble was bursting, multimedia was lacking a vision of potential future scenarios and applications. Within this research paper the potentials, applications, and market available solutions of mobile ambient multimedia are studied. The different features of ambient mobile multimedia are manifold and include wearable computers, adaptive software, context awareness, ubiquitous computers, middleware, and wireless networks. The paper especially focuses on algorithms and methods that can be utilized to realize modern mobile ambient systems.

Insecticidal activity of plant lectins and potential application in crop protection.

PubMed

Macedo, Maria Lígia R; Oliveira, Caio F R; Oliveira, Carolina T

2015-01-27

Lectins constitute a complex group of proteins found in different organisms. These proteins constitute an important field for research, as their structural diversity and affinity for several carbohydrates makes them suitable for numerous biological applications. This review addresses the classification and insecticidal activities of plant lectins, providing an overview of the applicability of these proteins in crop protection. The likely target sites in insect tissues, the mode of action of these proteins, as well as the use of lectins as biotechnological tools for pest control are also described. The use of initial bioassays employing artificial diets has led to the most recent advances in this field, such as plant breeding and the construction of fusion proteins, using lectins for targeting the delivery of toxins and to potentiate expected insecticide effects. Based on the data presented, we emphasize the contribution that plant lectins may make as tools for the development of integrated insect pest control strategies.

Application of laser-induced breakdown spectroscopy to the analysis of algal biomass for industrial biotechnology

NASA Astrophysics Data System (ADS)

Pořízka, P.; Prochazka, D.; Pilát, Z.; Krajcarová, L.; Kaiser, J.; Malina, R.; Novotný, J.; Zemánek, P.; Ježek, J.; Šerý, M.; Bernatová, S.; Krzyžánek, V.; Dobranská, K.; Novotný, K.; Trtílek, M.; Samek, O.

2012-08-01

We report on the application of laser-induced breakdown spectroscopy (LIBS) to the determination of elements distinctive in terms of their biological significance (such as potassium, magnesium, calcium, and sodium) and to the monitoring of accumulation of potentially toxic heavy metal ions in living microorganisms (algae), in order to trace e.g. the influence of environmental exposure and other cultivation and biological factors having an impact on them. Algae cells were suspended in liquid media or presented in a form of adherent cell mass on a surface (biofilm) and, consequently, characterized using their spectra. In our feasibility study we used three different experimental arrangements employing double-pulse LIBS technique in order to improve on analytical selectivity and sensitivity for potential industrial biotechnology applications, e.g. for monitoring of mass production of commercial biofuels, utilization in the food industry and control of the removal of heavy metal ions from industrial waste waters.

Magnetic induction tomography of objects for security applications

NASA Astrophysics Data System (ADS)

Ward, Rob; Joseph, Max; Langley, Abbi; Taylor, Stuart; Watson, Joe C.

2017-10-01

A coil array imaging system has been further developed from previous investigations, focusing on designing its application for fast screening of small bags or parcels, with a view to the production of a compact instrument for security applications. In addition to reducing image acquisition times, work was directed toward exploring potential cost effective manufacturing routes. Based on magnetic induction tomography and eddy-current principles, the instrument captured images of conductive targets using a lock-in amplifier, individually multiplexing signals between a primary driver coil and a 20 by 21 imaging array of secondary passive coils constructed using a reproducible multiple tile design. The design was based on additive manufacturing techniques and provided 2 orthogonal imaging planes with an ability to reconstruct images in less than 10 seconds. An assessment of one of the imaging planes is presented. This technique potentially provides a cost effective threat evaluation technique that may compliment conventional radiographic approaches.

Bedside functional brain imaging in critically-ill children using high-density EEG source modeling and multi-modal sensory stimulation.

PubMed

Eytan, Danny; Pang, Elizabeth W; Doesburg, Sam M; Nenadovic, Vera; Gavrilovic, Bojan; Laussen, Peter; Guerguerian, Anne-Marie

2016-01-01

Acute brain injury is a common cause of death and critical illness in children and young adults. Fundamental management focuses on early characterization of the extent of injury and optimizing recovery by preventing secondary damage during the days following the primary injury. Currently, bedside technology for measuring neurological function is mainly limited to using electroencephalography (EEG) for detection of seizures and encephalopathic features, and evoked potentials. We present a proof of concept study in patients with acute brain injury in the intensive care setting, featuring a bedside functional imaging set-up designed to map cortical brain activation patterns by combining high density EEG recordings, multi-modal sensory stimulation (auditory, visual, and somatosensory), and EEG source modeling. Use of source-modeling allows for examination of spatiotemporal activation patterns at the cortical region level as opposed to the traditional scalp potential maps. The application of this system in both healthy and brain-injured participants is demonstrated with modality-specific source-reconstructed cortical activation patterns. By combining stimulation obtained with different modalities, most of the cortical surface can be monitored for changes in functional activation without having to physically transport the subject to an imaging suite. The results in patients in an intensive care setting with anatomically well-defined brain lesions suggest a topographic association between their injuries and activation patterns. Moreover, we report the reproducible application of a protocol examining a higher-level cortical processing with an auditory oddball paradigm involving presentation of the patient's own name. This study reports the first successful application of a bedside functional brain mapping tool in the intensive care setting. This application has the potential to provide clinicians with an additional dimension of information to manage critically-ill children and adults, and potentially patients not suited for magnetic resonance imaging technologies.

Development and Application of Eddy Current Sensor Arrays for Process Integrated Inspection of Carbon Fibre Preforms.

PubMed

Berger, Dietrich; Lanza, Gisela

2017-12-21

This publication presents the realisation of a sensor concept, which is based on eddy current testing, to detect textile defects during preforming of semi-finished carbon fibre parts. The presented system has the potential for 100% control of manufactured carbon fibre based components, allowing the immediate exclusion of defective parts from further process steps. The core innovation of this system is given by the high degree of process integration, which has not been implemented in the state of the art. The publication presents the functional principle of the sensor that is based on half-transmission probes as well as the signals that can be gained by its application. Furthermore, a method to determine the optimum sensor resolution is presented as well as the sensor housing and its integration in the preforming process.

Young bamboo culm: Potential food as source of fiber and starch.

PubMed

Felisberto, Mária Herminia Ferrari; Miyake, Patricia Satie Endo; Beraldo, Antonio Ludovico; Clerici, Maria Teresa Pedrosa Silva

2017-11-01

With the objective of widening the use of bamboo in the food industry, the present work aimed to produce and characterize the young bamboo culm flours from varieties Dendrocalamus asper, Bambusa tuldoides and Bambusa vulgaris as potential sources of fiber and starch. The young culms were collected, cut in three sections (bottom, middle, top), processed into flour, and they were physically, chemically and technologically analyzed. The data were obtained in triplicate and evaluated by means of average differences, using analysis of variance (ANOVA) and Scott-Knott test (p<0.05). The young bamboo culms flours presented low values for moisture content (<10g/100g), protein, lipids and ash contents (<3g/100g). Regarding the carbohydrates profile, the flours were significantly different in their sugar, starch and total fiber contents. All flour samples presented a potential for fiber extraction (>60g/100g), and the varieties B. vulgaris and D. asper, presented an additional potential for starch extraction (16 and 10g/100g, respectively). Regarding technological characteristics, all flours presented bright yellow color, lightly acidic pH (>5.0), water solubility index (WSI) lower to 2.5%, excepting D. asper, which presented a WSI superior to 7.5%. In this way, the evaluated young bamboo culms present potential application in the food industry as flours and as source of fibers; in addition, the varieties D. asper and B. vulgaris can also be used for starch extraction. Copyright © 2017 Elsevier Ltd. All rights reserved.

Analyzing the threat of unmanned aerial vehicles (UAV) to nuclear facilities

DOE PAGES

Solodov, Alexander; Williams, Adam; Al Hanaei, Sara; ...

2017-04-18

Unmanned aerial vehicles (UAV) are among the major growing technologies that have many beneficial applications, yet they can also pose a significant threat. Recently, several incidents occurred with UAVs violating privacy of the public and security of sensitive facilities, including several nuclear power plants in France. The threat of UAVs to the security of nuclear facilities is of great importance and is the focus of this work. This paper presents an overview of UAV technology and classification, as well as its applications and potential threats. We show several examples of recent security incidents involving UAVs in France, USA, and Unitedmore » Arab Emirates. Further, the potential threats to nuclear facilities and measures to prevent them are evaluated. The importance of measures for detection, delay, and response (neutralization) of UAVs at nuclear facilities are discussed. An overview of existing technologies along with their strength and weaknesses are shown. Finally, the results of a gap analysis in existing approaches and technologies is presented in the form of potential technological and procedural areas for research and development. Furthermore based on this analysis, directions for future work in the field can be devised and prioritized.« less

Application of electron paramagnetic resonance imaging to the characterization of the Ultem(R) exposed to 1 MeV electrons. Correlation of radical density data to tiger code calculations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suleman, N.K.

1994-12-01

A major long-term goal of the Materials Division at the NASA Langley Research Center is the characterization of new high-performance materials that have potential applications in the aircraft industry, and in space. The materials used for space applications are often subjected to a harsh and potentially damaging radiation environment. The present study constitutes the application of a novel technique to obtain reliable data for ascertaining the molecular basis for the resilience and durability of materials that have been exposed to simulated space radiations. The radiations of greatest concern are energetic electrons and protons, as well as galactic cosmic rays. Presently,more » the effects of such radiation on matter are not understood in their entirety. It is clear however, that electron radiation causes ionization and homolytic bond rupture, resulting in the formation of paramagnetic spin centers in the polymer matrices of the structural materials. Since the detection and structure elucidation of paramagnetic species are most readily accomplished using Electron Paramagnetic Resonance (EPR) Spectroscopy, the NASA LaRC EPR system was brought back on-line during the 1991 ASEE term. The subsequent 1992 ASEE term was devoted to the adaptation of the EPR core system to meet the requirements for EPR Imaging (EPRI), which provides detailed information on the spatial distribution of paramagnetic species in bulk media. The present (1994) ASEE term was devoted to the calibration of this EPR Imaging system, as well as to the application of this technology to study the effects of electron irradiation on Ultem(exp R), a high performance polymer which is a candidate for applications in aerospace. The Ultem was exposed to a dose of 2.4 x 10(exp 9) Rads (1-MeV energy/electron) at the LaRC electron accelerator facility. Subsequently, the exposed specimens were stored in liquid nitrogen, until immediately prior to analyses by EPRI.« less

Controlled, Site-Specific Functionalization of Carbon Nanotubes with Diazonium Salts

NASA Technical Reports Server (NTRS)

Tour, James M.

2013-01-01

This work uses existing technologies to prepare a crossbar architecture of nano tubes, wherein one nanotube is fixed to a substrate, and a second nanotube is suspended a finite distance above. Both nano tubes can be individually addressed electrically. Application of opposite potentials to the two tubes causes the top tube to deform and to essentially come into contact with the lower tube. Contact here refers not to actual, physical contact, but rather within an infinitesimally small distance referred to as van der Walls contact, in which the entities may influence each other on a molecular and electronic scale. First, the top tube is physically deformed, leading to a potentially higher chemical reactivity at the point of deformation, based on current understanding of the effects of curvature strain on reactivity. This feature would allow selective functionalization at the junction via reaction with diazonium salts. Secondly, higher potential is achieved at the point of "cross" between the tubes. In a pending patent application, a method is claimed for directed self-assembly of molecular components onto the surface of metal or conductive materials by application of potential to the metal or conductive surface. In another pending patent application, a method is claimed for attaching molecules to the surface of nanotubes via the use of reactive diazonium salts. In the present invention, the directed functionalization of the crossed-nanotube junctions by applying a potential to the ends of the nanotubes in the presence of reactive diazonium slats, or other reactive molecular species is claimed. The diazonium salts are directed by the potential existing at the junction to react with the surface of the nanotube, thus placing functional molecular components at the junctions. The crossed nano tubes therefore provide a method of directly addressing the functionalized molecules, which have been shown to function as molecular switches, molecular wires, and in other capacities and uses. Site-specific functionalization may enable the use of nanotubes in molecular electronic applications because device functionality is critical at the cross points.

Electric potential and electric field imaging

NASA Astrophysics Data System (ADS)

Generazio, E. R.

2017-02-01

The technology and methods for remote quantitative imaging of electrostatic potentials and electrostatic fields in and around objects and in free space is presented. Electric field imaging (EFI) technology may be applied to characterize intrinsic or existing electric potentials and electric fields, or an externally generated electrostatic field made be used for "illuminating" volumes to be inspected with EFI. The baseline sensor technology (e-Sensor) and its construction, optional electric field generation (quasi-static generator), and current e-Sensor enhancements (ephemeral e-Sensor) are discussed. Demonstrations for structural, electronic, human, and memory applications are shown. This new EFI capability is demonstrated to reveal characterization of electric charge distribution creating a new field of study embracing areas of interest including electrostatic discharge (ESD) mitigation, crime scene forensics, design and materials selection for advanced sensors, dielectric morphology of structures, tether integrity, organic molecular memory, and medical diagnostic and treatment efficacy applications such as cardiac polarization wave propagation and electromyography imaging.

Investigation of immiscible systems and potential applications

NASA Technical Reports Server (NTRS)

Markworth, A. J.; Oldfield, W.; Duga, J.; Gelles, S. H.

1975-01-01

The droplet coalescence kinetics at 0 g and 1 g were considered for two systems which contained liquid droplets in a host liquid. One of these (Al-In) typified a system containing a liquid phase miscibility gap and the order (oil-water) a mixture of two essentially insoluble liquids. A number of coalescence mechanisms potentially prominent at low g in this system were analyzed and explanations are presented for the observed unusual stability of the emulsion. Ground base experiments were conducted on the coalescence of In droplets in and Al-In alloy during cooling through the miscibility gap at different cooling rates. These were in qualitative agreement with the computer simulation. Potential applications for systems with liquid phase miscibility gaps were explored. Possibilities included superconductors, electrical contact materials, superplastic materials, catalysts, magnetic materials, and others. The role of space processing in their production was also analyzed.

Aspects of food processing and its effect on allergen structure.

PubMed

Paschke, Angelika

2009-08-01

The article summarizes current physical and chemical methods in food processing as storage, preparation, separation, isolation or purification and thermal application on the one hand as well as enzymatic treatment on the other and their impact on the properties of food proteins. Novel methods of food processing like high pressure, electric field application or irradiation and their impact on food allergens are presented. The EU project REDALL (Reduced Allergenicity of Processed Foods, Containing Animal Allergens: QLK1-CT-2002-02687) showed that by a combination of enzyme and heat treatment the allergic potential of hen's egg decreased about 100 fold. Clinical reactions do not appear anymore. An AiF-FV 12024 N project worked with fruits like mango, lychee and apple. Processed mango and lychee had no change in allergenic potential during heating while e. g. canning. Apple almost lost its allergenic potential after pasteurization in juice production.

Using the Periscope Live Video-Streaming Application for Global Pathology Education: A Brief Introduction.

PubMed

Fuller, Maren Y; Mukhopadhyay, Sanjay; Gardner, Jerad M

2016-07-21

Periscope is a live video-streaming smartphone application (app) that allows any individual with a smartphone to broadcast live video simultaneously to multiple smartphone users around the world. The aim of this review is to describe the potential of this emerging technology for global pathology education. To our knowledge, since the launch of the Periscope app (2015), only a handful of educational presentations by pathologists have been streamed as live video via Periscope. This review includes links to these initial attempts, a step-by-step guide for those interested in using the app for pathology education, and a summary of the pros and cons, including ethical/legal issues. We hope that pathologists will appreciate the potential of Periscope for sharing their knowledge, expertise, and research with a live (and potentially large) audience without the barriers associated with traditional video equipment and standard classroom/conference settings.

Cyanobacterial Toxins as Allelochemicals with Potential Applications as Algaecides, Herbicides and Insecticides

PubMed Central

Berry, John P.; Gantar, Miroslav; Perez, Mario H.; Berry, Gerald; Noriega, Fernando G.

2008-01-01

Cyanobacteria (“blue-green algae”) from marine and freshwater habitats are known to produce a diverse array of toxic or otherwise bioactive metabolites. However, the functional role of the vast majority of these compounds, particularly in terms of the physiology and ecology of the cyanobacteria that produce them, remains largely unknown. A limited number of studies have suggested that some of the compounds may have ecological roles as allelochemicals, specifically including compounds that may inhibit competing sympatric macrophytes, algae and microbes. These allelochemicals may also play a role in defense against potential predators and grazers, particularly aquatic invertebrates and their larvae. This review will discuss the existing evidence for the allelochemical roles of cyanobacterial toxins, as well as the potential for development and application of these compounds as algaecides, herbicides and insecticides, and specifically present relevant results from investigations into toxins of cyanobacteria from the Florida Everglades and associated waterways. PMID:18728763

Development and Application of Microfabricated Chemical Gas Sensors For Aerospace Applications

NASA Technical Reports Server (NTRS)

Hunter, G. W.; Neudeck, P. G.; Fralick, G.; Thomas, V.; Liu, C. C.; Wu, Q. H.; Sawayda, M. S.; Jin, A.; Hammond, J.; Makel, D.;

Genetic Technology and Agricultural Development

ERIC Educational Resources Information Center

Staub, William J.; Blase, Melvin G.

1971-01-01

Examines the nature, application, limits and potential of applied genetics in plant breeding as a factor in South Asian agricultural development. Concludes other factors were also present in recent agricultural growth, and indicates some economic implications of continued growth, including problems of employment of displaced rural workers. (AL)

Where the Cloud Meets the Commons

ERIC Educational Resources Information Center

Ipri, Tom

2011-01-01

Changes presented by cloud computing--shared computing services, applications, and storage available to end users via the Internet--have the potential to seriously alter how libraries provide services, not only remotely, but also within the physical library, specifically concerning challenges facing the typical desktop computing experience.…

INITIAL SCREENING OF THERMAL DESORPTION FOR SOIL REMEDIATION

EPA Science Inventory

The purpose of the paper is to present procedures for collecting and evaluating key data that affect the potential application of thermal desorption for a specific site. These data are defined as 'criticalsuccess factors'. The screening prodcedure can be used to peerform an ini...

Artificial Intelligence and CALL.

ERIC Educational Resources Information Center

Underwood, John H.

The potential application of artificial intelligence (AI) to computer-assisted language learning (CALL) is explored. Two areas of AI that hold particular interest to those who deal with language meaning--knowledge representation and expert systems, and natural-language processing--are described and examples of each are presented. AI contribution…

Demodulator 1971.

ERIC Educational Resources Information Center

GTE Lenkurt, San Carlos, CA.

Twelve articles dealing with telecommunications systems are presented. The articles are for the most part considerations of some of the potential uses and of the technical problems of communication networks used for commercial and educational purposes. Among the topics are the application of communication technology to control pollution, the CATV…

Efficacy of Web-Based Instruction to Provide Training on Federal Motor Carrier Safety Regulations

DOT National Transportation Integrated Search

2011-05-01

This report presents an evaluation of the current state-of-the-art Web-based instruction (WBI), reviews the current computer platforms of potential users of WBI, reviews the current status of WBI applications for Federal Motor Carrier Safety Administ...

Effectively Communicating Science to Extension Audiences

ERIC Educational Resources Information Center

Robinson, Patrick

2013-01-01

This article discusses the concept of "framing" within the context of relevant communication and psychological research and considers its potential applicability to Extension science communication. Examples of research-based support for the framing of scientific issues are presented, along with a literature-based discussion of the…

Statistical Interpretation of the Local Field Inside Dielectrics.

ERIC Educational Resources Information Center

Berrera, Ruben G.; Mello, P. A.

1982-01-01

Compares several derivations of the Clausius-Mossotti relation to analyze consistently the nature of approximations used and their range of applicability. Also presents a statistical-mechanical calculation of the local field for classical system of harmonic oscillators interacting via the Coulomb potential. (Author/SK)

Performance-Based Measurement: Action for Organizations and HPT Accountability

ERIC Educational Resources Information Center

Larbi-Apau, Josephine A.; Moseley, James L.

2010-01-01

Basic measurements and applications of six selected general but critical operational performance-based indicators--effectiveness, efficiency, productivity, profitability, return on investment, and benefit-cost ratio--are presented. With each measurement, goals and potential impact are explored. Errors, risks, limitations to measurements, and a…

DEVELOPMENT OF RISK ASSESSMENT METHODOLOGY FOR MUNICIPAL SLUDGE INCINERATION

EPA Science Inventory

This is one of a series of reports that present methodologies for assessing the potential risks to humans or other organisms from the disposal or reuse of municipal sludge. he sludge management practices addressed by this series include land application practices, distribution an...