Sample records for present previously unpublished

  1. First Nuclear DNA Amounts in more than 300 Angiosperms

    PubMed Central

    ZONNEVELD, B. J. M.; LEITCH, I. J.; BENNETT, M. D.

    2005-01-01

    • Background and Aims Genome size (DNA C-value) data are key biodiversity characters of fundamental significance used in a wide variety of biological fields. Since 1976, Bennett and colleagues have made scattered published and unpublished genome size data more widely accessible by assembling them into user-friendly compilations. Initially these were published as hard copy lists, but since 1997 they have also been made available electronically (see the Plant DNA C-values database www.kew.org/cval/homepage.html). Nevertheless, at the Second Plant Genome Size Meeting in 2003, Bennett noted that as many as 1000 DNA C-value estimates were still unpublished and hence unavailable. Scientists were strongly encouraged to communicate such unpublished data. The present work combines the databasing experience of the Kew-based authors with the unpublished C-values produced by Zonneveld to make a large body of valuable genome size data available to the scientific community. • Methods C-values for angiosperm species, selected primarily for their horticultural interest, were estimated by flow cytometry using the fluorochrome propidium iodide. The data were compiled into a table whose form is similar to previously published lists of DNA amounts by Bennett and colleagues. • Key Results and Conclusions The present work contains C-values for 411 taxa including first values for 308 species not listed previously by Bennett and colleagues. Based on a recent estimate of the global published output of angiosperm DNA C-value data (i.e. 200 first C-value estimates per annum) the present work equals 1·5 years of average global published output; and constitutes over 12 % of the latest 5-year global target set by the Second Plant Genome Size Workshop (see www.kew.org/cval/workshopreport.html). Hopefully, the present example will encourage others to unveil further valuable data which otherwise may lie forever unpublished and unavailable for comparative analyses. PMID:15905300

  2. The Nature of Happiness.

    ERIC Educational Resources Information Center

    Maslow, Abraham H.

    1991-01-01

    Presents previously unpublished paper written by Abraham Maslow in November 1964. Maslow discusses the concept of happiness, suggesting that happiness is a lot more complicated than its standard, hedonistic definition as merely the absence of pain. (Author/ABL)

  3. Developing Friendship and Intimacy.

    ERIC Educational Resources Information Center

    Maslow, Abraham H.

    1991-01-01

    Presents previously unpublished paper written by Abraham Maslow in April 1968 in which Maslow speculates on the issue that society had become pathologically individualistic and needed to develop better means of facilitating close relationships among people. (Author/ABL)

  4. Experiential Exercises for Gratitude.

    ERIC Educational Resources Information Center

    Maslow, Abraham H.

    1991-01-01

    Presents previously unpublished paper written by Abraham Maslow in which Maslow discusses gratitude. Claims it is important to acquire the ability to "count one's blessings" and appreciate what is possessed without experiencing its loss. Offers suggestions on applying this principle. (ABL)

  5. How We Diminish Ourselves.

    ERIC Educational Resources Information Center

    Maslow, Abraham H.

    1991-01-01

    Presents previously unpublished paper written by Abraham Maslow, written in November 1966, in which Maslow confronts the issue why so few people are truly self-actualizing. Discusses the Jonah Complex, the willful evasion of personal capacity for growth and accomplishment in life. (Author/ABL)

  6. How to Experience the Unitive Life.

    ERIC Educational Resources Information Center

    Maslow, Abraham H.

    1991-01-01

    Presents previously unpublished paper written by Abraham Maslow during the mid-1960s in which he outlined dozens of methods for overcoming ennui and "burnout" thereby enriching peoples' lives. Discusses the realm of honesty, pride, and dignity and entering the being-realm. (Author/ABL)

  7. Phenotypic Variation and FMRP Levels in Fragile X

    ERIC Educational Resources Information Center

    Loesch, Danuta Z.; Huggins, Richard M.; Hagerman, Randi J.

    2004-01-01

    Data on the relationships between cognitive and physical phenotypes, and a deficit of fragile X mental retardation 1 (FMR1) gene-specific protein product, FMRP, are presented and discussed in context with earlier findings. The previously unpublished results obtained, using standard procedures of regression and correlations, showed highly…

  8. Proceedings - Management and productivity of western-montane forest soils

    Treesearch

    Alan E. Harvey; Leon F. Neuenschwander

    1991-01-01

    Includes 35 papers and six poster synopses presenting state-of-the-art knowledge on the nature and problems of integrating soils information and expertise into management of inland western forest resources. Papers emphasize regional information, but include data from world literature and previously unpublished material from regional experts.

  9. [I.P. Pavlov and L.A. Orbeli: new materials in stocks of the military medical museum].

    PubMed

    Budko, A A; Nazartsev, B I

    2013-01-01

    The article presents the previously unpublished letter of I.P. Pavlov to L.A. Orbeli being kept in stocks of the Military medical museum of military medical museum of the S.M. Kirov military medical academy. The needed commentaries are given.

  10. Investigating Evolutionary Biology in the Laboratory.

    ERIC Educational Resources Information Center

    McComas, William F., Ed.

    This document presents a collection of useful laboratory-based activities for teaching about evolution. Some of the activities in this monograph are previously unpublished exercises, some are new versions of well-known labs, a few make useful classroom demonstrations, and several require somewhat sophisticated equipment. As a group, the activities…

  11. Principal Facts for Gravity Data Collected in Wisconsin: A Web Site and CD-ROM for Distribution of Data

    USGS Publications Warehouse

    Snyder, Stephen L.; Geister, Daniel W.; Daniels, David L.; Ervin, C. Patrick

    2004-01-01

    Principal facts for 40,488 gravity stations covering the entire state of Wisconsin are presented here in digital form. This is a compilation of previously published data collected between 1948 and 1992 from numerous sources, along with over 10,000 new gravity stations collected by the USGS since 1999. Also included are 550 gravity stations from previously unpublished sources. Observed gravity and complete-Bouguer gravity anomaly data for this statewide compilation are included here. Altogether, 14 individual surveys are presented here.

  12. The Dermacentor (Acari, Ixodida, Ixodidae) of Mexico: hosts, geographical distribution and new records

    PubMed Central

    Guzmán-Cornejo, Carmen; Robbins, Richard G.; Guglielmone, Alberto A.; Montiel-Parra, Griselda; Rivas, Gerardo; Pérez, Tila María

    2016-01-01

    Abstract Distribution and host data from published literature and previously unpublished collection records are provided for all nine species of the Holarctic tick genus Dermacentor that are known to occur in Mexico, as well as two species that may occur there. Parasite-host and host-parasite lists are presented, together with a gazetteer of collection localities and their geographical coordinates. PMID:27110147

  13. In Search of Gender Free Paradigms for Computer Science Education. [Proceedings of a Preconference Research Workshop at the National Educational Computing Conference (Nashville, Tennessee, June 24, 1990).

    ERIC Educational Resources Information Center

    Martin, C. Dianne, Ed.; Murchie-Beyma, Eric, Ed.

    This monograph includes nine papers delivered at a National Educational Computing Conference (NECC) preconference workshop, and a previously unpublished paper on gender and attitudes. The papers, which are presented in four categories, are: (1) "Report on the Workshop: In Search of Gender Free Paradigms for Computer Science Education"…

  14. An e-mail survey identified unpublished studies for systematic reviews.

    PubMed

    Reveiz, Ludovic; Cardona, Andres Felipe; Ospina, Edgar Guillermo; de Agular, Sylvia

    2006-07-01

    A large number of trials remain difficult to locate or unpublished for systematic reviews. The objective of this article was to determine the usefulness of making e-mail contact with authors of clinical trials and literature reviews found in MEDLINE to identify unpublished or difficult to locate Randomized Controlled Trials (RCTs). A structured search for detecting RCTs in MEDLINE was made from January 1999 to June 2003; a questionnaire was sent to a random sample of 525 author's mails. Those RCTs obtained were sought in MEDLINE, EMBASE, the Cochrane Controlled Trials Register, LILACS, and ongoing registers. 40 (7.6%) replies were received; 10 previously undescribed and unpublished RCTs and 21 unregistered ongoing RCTs were found. The most frequently given reasons for not publishing were: lack of time for finalizing the statistical analysis and preparing the manuscript, contractual obligations with the pharmaceutical industry, methodologic errors in designing, and editorial rejection. Using the e-mails of authors detected by the search in electronic databases could contribute toward detecting potentially relevant ongoing or unpublished RCTs enabling rapid, straightforward, low-cost systematic review; in addition, the results of this study support the need of universal registration of all studies at their inception.

  15. Dividing the glory of the fathers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leskov, S.

    1993-05-01

    theere is an intense debate between the Russian secret service and nuclear scientists on the history of Soviet nuclear weapons. The author does not wish to take sides in this controversy, but has gathered materials on the role of the intelligence service in the creation of th Soviet atomic bomb from a variety of sources. He presents in this article previously unpublished information made available to him by Colonel Vladimir Barkovski of the Russian intelligence services.

  16. Preface to The Diary of Vaslav Nijinsky by Alfred Adler, MD.

    PubMed

    Ansbacher, H L

    1981-07-01

    This is a previously unpublished work by Alfred Adler that was written in 1936 as a preface to The Diary of Vaslav Nijinsky. A theory of schizophrenia is described in which characteristic prepsychotic features, especially lack of social interest and oversensitivity to real and imagined slights, lead to increasing irrationalism and preoccupation with grandiose ideas. The establishment of a cooperative therapeutic relationship and the instilling of hope are presented as central factors for successful treatment.

  17. How health technology assessment agencies address the issue of unpublished data.

    PubMed

    Kreis, Julia; Panteli, Dimitra; Busse, Reinhard

    2014-01-01

    Reporting bias potentially threatens the validity of results in health technology assessment (HTA) reports. Our study aimed to explore policies and practices of HTA agencies regarding strategies to include previously unpublished data in their assessments, focusing on requests to industry for unpublished data. We included international HTA agencies with publicly available methods papers as well as HTA reports. From the methods papers and recent reports we extracted information on requests to industry and on searches in trial registries, regulatory authority Web sites and for conference abstracts. Eighteen HTA agencies and seventy-three reports were included. Agencies' methods papers showed variability regarding requests to industry (requests are routinely carried out in seven cases, not mentioned in six, at the discretion of HTA authors in three, and based on manufacturer applications in two), which were reflected in the reports investigated. As reporting of requests was limited, it often remained unclear whether unpublished data had been received. Searches in trial registries, at regulatory authorities or for conference abstracts are described as a routine or optional part of the search strategy in the methods papers of 9, 11, and 8 included agencies, respectively. A total of 52 percent, 39 percent, and 16 percent of reports described searches in trial registries, at regulatory agencies, and hand searching of conference proceedings. International HTA agencies currently differ considerably in their efforts to address the issue of unpublished data. Requests to industry may constitute one strategy to access and include unpublished data, while agencies can learn from each other concerning successful practice.

  18. Further efforts in optimizing nonlinear optical molecules

    NASA Astrophysics Data System (ADS)

    Dirk, Carl W.; Caballero, Noel; Tan, Alarice; Kuzyk, Mark G.; Cheng, Lap-Tak A.; Katz, Howard E.; Shilling, Marcia; King, Lori A.

    1993-02-01

    We summarize some of our past work in the field on optimizing molecules for second order and third order nonlinear optical applications. We also present some previously unpublished results suggesting a particular optimization of the popular cyano- and nitrovinyl acceptor groups. In addition we provide some new quadratic electro-optic results which serve to further verify our choice of a restricted three-level model suitable for optimizing third order nonlinearities in molecules. Finally we present a new squarylium dye with a large third order optical nonlinearity (-9.5 X 10-34 cm7/esu2; EFISH (gamma) at 1906 nm).

  19. Book Review: John von Neumann and the foundations of quantum physics. (Vienna Circle Institute yearbook (2000), 8) Miklos Redei and Michael Stoltzner (Eds.); Kluwer Academic Publishers, Dordrecht, 2001, pp., US 125, ISBN 0792368126

    NASA Astrophysics Data System (ADS)

    Lupher, Tracy

    2003-12-01

    Some people may be surprised to learn that John von Neumann's work on the foundations of quantum physics went far beyond what is contained within the pages of his Mathematical Foundations of Quantum Mechanics (MFQM) (von Neumann, 1955). However, this narrow focus often ignores von Neumann's later work on quantum logic and what are now called in his honor, von Neumann algebras. This volume honoring von Neumann's contributions to physics is unique in that, while it contains 12 papers that examine various aspects of von Neumann's work, it also contains two of his previously unpublished papers and some of his previously unpublished correspondence.

  20. Hydrodynamics of strongly coupled non-conformal fluids from gauge/gravity duality

    NASA Astrophysics Data System (ADS)

    Springer, Todd

    2009-08-01

    The subject of relativistic hydrodynamics is explored using the tools of gauge/gravity duality. A brief literature review of AdS/CFT and gauge/gravity duality is presented first. This is followed by a pedagogical introduction to the use of these methods in determining hydrodynamic dispersion relations, w(q), of perturbations in a strongly coupled fluid. Shear and sound mode perturbations are examined in a special class of gravity duals: those where the matter supporting the metric is scalar in nature. Analytical solutions (to order q^4 and q^3 respectively) for the shear and sound mode dispersion relations are presented for a subset of these backgrounds. The work presented here is based on previous publications by the same author, though some previously unpublished results are also included. In particular, the subleading term in the shear mode dispersion relation is analyzed using the AdS/CFT correspondence without any reference to the black hole membrane paradigm.

  1. Women’s Sexuality: Behaviors, Responses, and Individual Differences

    PubMed Central

    Andersen, Barbara L.; Cyranowski, Jill M.

    2009-01-01

    Classic and contemporary approaches to the assessment of female sexuality are discussed. General approaches, assessment strategies, and models of female sexuality are organized within the conceptual domains of sexual behaviors, sexual responses (desire, excitement, orgasm, and resolution), and individual differences, including general and sex-specific personality models. Where applicable, important trends and relationships are highlighted in the literature with both existing reports and previously unpublished data. The present conceptual overview highlights areas in sexual assessment and model building that are in need of further research and theoretical clarification. PMID:8543712

  2. Miscellaneous lunar tables from Babylon

    NASA Astrophysics Data System (ADS)

    Steele, J. M.

    2006-03-01

    In the process of searching through unpublished astronomical material in the cuneiform collection of the British Museum I have identified a number of new tabular astronomical texts of the kind published by O. Neugebauer in Astronomical Cuneiform Texts [1955] (hereafter:ACT). Several lunar tables were published in Steele [2002]. Here I publish another group of lunar ephemerides and related texts identified over the past five years, together with two tablets (BM 36961 and BM 37021) identified and described by A. Aaboe but never published, and two previously unpublished joins to ACT tablets (ACT No. 3a and ACT No. 4a) made by A. Sachs and A. Aaboe.

  3. Trace-element analyses of core samples from the 1967-1988 drillings of Kilauea Iki lava lake, Hawaii

    USGS Publications Warehouse

    Helz, Rosalind Tuthill

    2012-01-01

    This report presents previously unpublished analyses of trace elements in drill core samples from Kilauea Iki lava lake and from the 1959 eruption that fed the lava lake. The two types of data presented were obtained by instrumental neutron-activation analysis (INAA) and energy-dispersive X-ray fluorescence analysis (EDXRF). The analyses were performed in U.S. Geological Survey (USGS) laboratories from 1989 to 1994. This report contains 93 INAA analyses on 84 samples and 68 EDXRF analyses on 68 samples. The purpose of the study was to document trace-element variation during chemical differentiation, especially during the closed-system differentiation of Kilauea Iki lava lake.

  4. Geologic Map of the Umiat Quadrangle, Alaska

    USGS Publications Warehouse

    Mull, Charles G.; Houseknecht, David W.; Pessel, G.H.; Garrity, Christopher P.

    2004-01-01

    This geologic map of the Umiat quadrangle is a compilation of previously published USGS geologic maps and unpublished mapping done for the Richfield Oil Corporation. Geologic mapping from these three primary sources was augmented with additional unpublished map data from British Petroleum Company. This report incorporates recent revisions in stratigraphic nomenclature. Stratigraphic and structural interpretations were revised with the aid of modern high-resolution color infrared aerial photographs. The revised geologic map was checked in the field during the summers of 2001 and 2002. The geologic unit descriptions on this map give detailed information on thicknesses, regional distributions, age determinations, and depositional environments. The paper version of this map is available for purchase from the USGS Store.

  5. [An unpublished contribution of Melanie Klein "On Reassurance"].

    PubMed

    Frank, Claudia; Klein, Melanie

    2005-01-01

    Melanie Klein's unpublished paper on reassurance is presented in German translation. The author shows that it was a contribution to Glover's investigation on psychoanalytic technique in the 1930s. The paper is discussed against the background of the technical discussions conducted in London at that time (e. g. M. Schmideberg, J. Strachey) and of Klein's relevant publications. Although Klein consistently considered "correct" interpretation to be the most effective means of reassurance, she occasionally also accepted a non-interpreting approach. In this respect the paper presented here goes further than any other of her writings.

  6. Comparative Education in the Nineteenth Century

    ERIC Educational Resources Information Center

    Brickman, William W.

    2010-01-01

    In this previously unpublished essay, William W. Brickman complicates the traditional conception of the historical foundations of comparative education--that is, the role of Marc-Antoine Julian as a "father figure." The article examines influences on Julian (by Cesar-Auguste Basset's influential publications, for example) and discusses…

  7. From the Palaeontological Collection of the Universalmuseum Joanneum - The Cenozoic Decapod Crustaceans (Crustacea: Malacostraca: Decapoda).

    PubMed

    Hyžný, Matúš; Gross, Martin

    2016-01-01

    Cenozoic decapod crustaceans housed in the collections of the Universalmuseum Joanneum (Graz, Austria) are reviewed. Previous descriptions, geographic and stratigraphic provenance and collection history are discussed. Altogether 72 specimens are figured, including five holotypes. Taxonomic affinity of previously unpublished material is addressed. Gebiacantha sp. from the middle Miocene of Wetzelsdorf is the first fossil record of the genus from the Paratethys.

  8. From the Palaeontological Collection of the Universalmuseum Joanneum – The Cenozoic Decapod Crustaceans (Crustacea: Malacostraca: Decapoda)

    PubMed Central

    Hyžný, Matúš; Gross, Martin

    2017-01-01

    Cenozoic decapod crustaceans housed in the collections of the Universalmuseum Joanneum (Graz, Austria) are reviewed. Previous descriptions, geographic and stratigraphic provenance and collection history are discussed. Altogether 72 specimens are figured, including five holotypes. Taxonomic affinity of previously unpublished material is addressed. Gebiacantha sp. from the middle Miocene of Wetzelsdorf is the first fossil record of the genus from the Paratethys. PMID:28239309

  9. Fuels and Engines | Transportation Research | NREL

    Science.gov Websites

    technologies can influence vehicle efficiency and use through changes in vehicle designs, driving habits, and -compound cetane number data through December 2016, including previously unpublished values that are results and agricultural waste, for use in transportation applications in California. Techno-economic analyses

  10. LiPISC: A Lightweight and Flexible Method for Privacy-Aware Intersection Set Computation

    PubMed Central

    Huang, Shiyong; Ren, Yi; Choo, Kim-Kwang Raymond

    2016-01-01

    Privacy-aware intersection set computation (PISC) can be modeled as secure multi-party computation. The basic idea is to compute the intersection of input sets without leaking privacy. Furthermore, PISC should be sufficiently flexible to recommend approximate intersection items. In this paper, we reveal two previously unpublished attacks against PISC, which can be used to reveal and link one input set to another input set, resulting in privacy leakage. We coin these as Set Linkage Attack and Set Reveal Attack. We then present a lightweight and flexible PISC scheme (LiPISC) and prove its security (including against Set Linkage Attack and Set Reveal Attack). PMID:27326763

  11. LiPISC: A Lightweight and Flexible Method for Privacy-Aware Intersection Set Computation.

    PubMed

    Ren, Wei; Huang, Shiyong; Ren, Yi; Choo, Kim-Kwang Raymond

    2016-01-01

    Privacy-aware intersection set computation (PISC) can be modeled as secure multi-party computation. The basic idea is to compute the intersection of input sets without leaking privacy. Furthermore, PISC should be sufficiently flexible to recommend approximate intersection items. In this paper, we reveal two previously unpublished attacks against PISC, which can be used to reveal and link one input set to another input set, resulting in privacy leakage. We coin these as Set Linkage Attack and Set Reveal Attack. We then present a lightweight and flexible PISC scheme (LiPISC) and prove its security (including against Set Linkage Attack and Set Reveal Attack).

  12. Teaching Science Out-of-School with Special Reference to Biology.

    ERIC Educational Resources Information Center

    Meyer, G. Rex, Ed.; Rao, A. N., Ed.

    This book contains a selection of previously unpublished papers from an international Asian symposium on out-of-school science activities. These papers include: "Educational and Social Values of Out-of-School Science" (Peter Kelly); "School Versus Out-of-School: An Artificial Dichotomy" (William Mayer); "Biology of…

  13. Chapter 10: Management recommendations

    Treesearch

    Deborah M. Finch; Janie Agyagos; Tracy McCarthey; Robert M. Marshall; Scott H. Stoleson; Mary J. Whitfield

    2000-01-01

    This chapter was developed over a series of meetings using a group-consensus process. Our recommendations are based on published results, on information compiled in the previous chapters, on expert opinion, and on unpublished data of conservation team members. This chapter is available as temporary guidance until the Recovery Plan for the southwestern willow flycatcher...

  14. Newly discovered Wolf-Rayet and weak emission-line central stars of planetary nebulae

    NASA Astrophysics Data System (ADS)

    DePew, K.; Parker, Q. A.; Miszalski, B.; De Marco, O.; Frew, D. J.; Acker, A.; Kovacevic, A. V.; Sharp, R. G.

    2011-07-01

    We present the spectra of 32 previously unpublished confirmed and candidate Wolf-Rayet ([WR]) and weak emission-line (WELS) central stars of planetary nebulae (CSPNe). 18 stars have been discovered in the Macquarie/AAO/Strasbourg Hα (MASH) PN survey sample, and we have also uncovered 14 confirmed and candidate [WR]s and WELS among the CSPNe of previously known PNe. Spectral classifications have been undertaken using both Acker & Neiner and Crowther, De Marco & Barlow schemes. 22 members in this sample are identified as probable [WR]s; the remaining 10 appear to be WELS. Observations undertaken as part of the MASH spectroscopic survey have now increased the number of known [WR]s by ˜30 per cent. This will permit a better analysis of [WR] subclass distribution, metallicity effects and evolutionary sequences in these uncommon objects.

  15. Malignant Mesothelioma in a Motor Vehicle Mechanic.

    PubMed

    Meisenkothen, Christopher

    2017-02-01

    Case reports remain an important source of data in the debate over the carcinogenic effect of asbestos-containing automotive friction products. This report documents a case of pleural mesothelioma accompanied by asbestos bodies in the lung tissue of a career auto mechanic with no other known sources of exposure. Previously unreported historical and contemporary exposure data are also discussed in the context of providing additional support for the proposition that work with asbestos-containing automotive products presents a risk of significant exposure. While there remains a body of negative epidemiology that fails to find an increased risk of disease among auto workers, those data must be approached with caution. Many of those studies have drawn technical criticisms, which are beyond the scope of this report, but they remain a key part of the legal defense mounted by defendant-companies who are involved in asbestos-related litigation. This ongoing debate provides the context for the continued relevance of case reports such as this one, as well as the presentation of new and previously unpublished exposure data.

  16. Do Premarital Education Programs Really Work? A Meta-Analytic Study

    ERIC Educational Resources Information Center

    Fawcett, Elizabeth B.; Hawkins, Alan J.; Blanchard, Victoria L.; Carroll, Jason S.

    2010-01-01

    Previous studies (J. S. Carroll & W. J. Doherty, 2003) have asserted that premarital education programs have a positive effect on program participants. Using meta-analytic methods of current best practices to look across the entire body of published and unpublished evaluation research on premarital education, we found a more complex pattern of…

  17. 37 CFR 202.22 - Acquisition and deposit of unpublished audio and audiovisual transmission programs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... unpublished audio and audiovisual transmission programs. 202.22 Section 202.22 Patents, Trademarks, and... REGISTRATION OF CLAIMS TO COPYRIGHT § 202.22 Acquisition and deposit of unpublished audio and audiovisual... and copies of unpublished audio and audiovisual transmission programs by the Library of Congress under...

  18. 37 CFR 202.22 - Acquisition and deposit of unpublished audio and audiovisual transmission programs.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... unpublished audio and audiovisual transmission programs. 202.22 Section 202.22 Patents, Trademarks, and... REGISTRATION OF CLAIMS TO COPYRIGHT § 202.22 Acquisition and deposit of unpublished audio and audiovisual... and copies of unpublished audio and audiovisual transmission programs by the Library of Congress under...

  19. 37 CFR 202.22 - Acquisition and deposit of unpublished audio and audiovisual transmission programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... unpublished audio and audiovisual transmission programs. 202.22 Section 202.22 Patents, Trademarks, and... REGISTRATION OF CLAIMS TO COPYRIGHT § 202.22 Acquisition and deposit of unpublished audio and audiovisual... and copies of unpublished audio and audiovisual transmission programs by the Library of Congress under...

  20. 37 CFR 202.22 - Acquisition and deposit of unpublished audio and audiovisual transmission programs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... unpublished audio and audiovisual transmission programs. 202.22 Section 202.22 Patents, Trademarks, and... REGISTRATION OF CLAIMS TO COPYRIGHT § 202.22 Acquisition and deposit of unpublished audio and audiovisual... and copies of unpublished audio and audiovisual transmission programs by the Library of Congress under...

  1. 12 CFR 911.7 - Availability of unpublished information by testimony.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Availability of unpublished information by testimony. 911.7 Section 911.7 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.7 Availability of unpublished...

  2. 12 CFR 911.8 - Availability of unpublished information by document.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Availability of unpublished information by document. 911.8 Section 911.8 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.8 Availability of unpublished...

  3. 12 CFR 911.7 - Availability of unpublished information by testimony.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Availability of unpublished information by testimony. 911.7 Section 911.7 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.7 Availability of unpublished...

  4. 12 CFR 911.8 - Availability of unpublished information by document.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Availability of unpublished information by document. 911.8 Section 911.8 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.8 Availability of unpublished...

  5. 12 CFR 911.8 - Availability of unpublished information by document.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Availability of unpublished information by document. 911.8 Section 911.8 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.8 Availability of unpublished...

  6. 12 CFR 911.8 - Availability of unpublished information by document.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Availability of unpublished information by document. 911.8 Section 911.8 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.8 Availability of unpublished...

  7. 12 CFR 911.7 - Availability of unpublished information by testimony.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Availability of unpublished information by testimony. 911.7 Section 911.7 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.7 Availability of unpublished...

  8. Efficacy, Safety and Mechanisms of Blood Flow Restricted Exercise

    NASA Technical Reports Server (NTRS)

    Ploutz-Snyder, Lori

    2009-01-01

    This 20 minute talk will review studies in the peer-reviewed literature related to the effectiveness of blood flow restricted exercise as an exercise training program. There is controversy regarding the talk with cover the effectiveness of various exercise protocols and these differences will be compared and contrasted. Unpublished data from my laboratory at Syracuse University will be presented (see other abstract), as well as some unpublished work from the labs of Manini, Clark and Rasmussen (none are NASA funded).

  9. Determining Hβ Color Indices for 23 δ Scuti Variable Stars

    NASA Astrophysics Data System (ADS)

    Bush, Tabitha C.; Hintz, E. G.; Shreeve, D. K.; Jorgenson, K.

    2010-01-01

    Color index is a fundamental characteristic in the study of δ Scuti variable stars. The then comprehensive catalog of δ Scutis compiled by Rodriguez et al. (Rodriguez, E. Lopez Gonzalez, M. J., & Lopez de Coca, P. 2000, A&AS, 144, 469) contains 636 δ Scuti stars and several characteristics of these stars, including Hβ color index. Of the 417 stars in this catalog brighter than 13th magnitude, about 20% of them are missing Hβ color index values. We present 23 of these previously unpublished values, calculated from a calibration relation using spectroscopic observations obtained at the Dominion Astrophysical Observatory of 167 δ Scuti stars north of -01 degrees declination and brighter than 13th magnitude.

  10. LIGA-based microsystem manufacturing:the electrochemistry of through-mold depostion and material properties.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kelly, James J.; Goods, Steven Howard

    2005-06-01

    The report presented below is to appear in ''Electrochemistry at the Nanoscale'', Patrik Schmuki, Ed. Springer-Verlag, (ca. 2005). The history of the LIGA process, used for fabricating dimensional precise structures for microsystem applications, is briefly reviewed, as are the basic elements of the technology. The principal focus however, is on the unique aspects of the electrochemistry of LIGA through-mask metal deposition and the generation of the fine and uniform microstructures necessary to ensure proper functionality of LIGA components. We draw from both previously published work by external researchers in the field as well as from published and unpublished studies frommore » within Sandia.« less

  11. Examples of Data Analysis with SPSS/PC+ Studentware.

    ERIC Educational Resources Information Center

    MacFarland, Thomas W.

    Intended for classroom use only, these unpublished notes contain computer lessons on descriptive statistics with files previously created in WordPerfect 4.2 and Lotus 1-2-3 Version 1.A for the IBM PC+. The statistical measures covered include Student's t-test with two independent samples; Student's t-test with a paired sample; Chi-square analysis;…

  12. Some Evidence on the Importance of Sticky Prices.

    ERIC Educational Resources Information Center

    Bils, Mark; Klenow, Peter J.

    2004-01-01

    We examine the frequency of price changes for 350 categories of goods and services covering about 70 percent of consumer spending, on the basis of unpublished data from the Bureau of Labor Statistics for 1995-97. In comparison with previous studies, we find much more frequent price changes, with haft of prices lasting less than 4.3 months. Even…

  13. Proceedings of the Conference on Application of Scanning Methodologies in Libraries (Beltsville, Maryland, November 17-18, 1988).

    ERIC Educational Resources Information Center

    Blamberg, Donald L., Ed.; And Others

    Planned and organized by the National Agricultural Library (NAL), the conference was designed to bring together people involved in scanning projects and to evaluate the feasibility of using hand-held scanning devices for transcribing bibliographic information during the cataloging and indexing processes. Ten previously unpublished papers and a…

  14. The Avant-Garde Film: A Reader of Theory and Criticism. Anthology Film Archives Series: 3.

    ERIC Educational Resources Information Center

    Sitney, P. Adams, Ed.

    This anthology is both a history of the avant-garde film genre and a compendium of theories of cinema articulated by major filmmakers. The 33 selections include several previously unpublished theoretical and critical articles and many articles that were especially translated into English for this collection. Other selections were drawn from…

  15. Maturity-onset diabetes of the young (MODY) in Brazil: Establishment of a national registry and appraisal of available genetic and clinical data.

    PubMed

    Giuffrida, Fernando M A; Moises, Regina S; Weinert, Leticia S; Calliari, Luis E; Manna, Thais Della; Dotto, Renata P; Franco, Luciana F; Caetano, Lilian A; Teles, Milena G; Lima, Renata Andrade; Alves, Crésio; Dib, Sergio A; Silveiro, Sandra P; Dias-da-Silva, Magnus R; Reis, Andre F

    2017-01-01

    Maturity-Onset Diabetes of the Young (MODY) comprises a heterogeneous group of monogenic forms of diabetes caused by mutations in at least 14 genes, but mostly by mutations in Glucokinase (GCK) and hepatocyte nuclear factor-1 homeobox A (HNF1A). This study aims to establish a national registry of MODY cases in Brazilian patients, assessing published and unpublished data. 311 patients with clinical characteristics of MODY were analyzed, with unpublished data on 298 individuals described in 12 previous publications and 13 newly described cases in this report. 72 individuals had GCK mutations, 9 described in Brazilian individuals for the first time. One previously unpublished novel GCK mutation, Gly178Ala, was found in one family. 31 individuals had HNF1A mutations, 2 described for the first time in Brazilian individuals. Comparisons of GCK probands vs HNF1A: age 16±11 vs 35±20years; age at diagnosis 11±8 vs 21±7years; BMI 19±6 vs 25±6kg/m 2 ; sulfonylurea users 5 vs 83%; insulin users 5 vs 17%; presence of arterial hypertension 0 vs. 33%, all p<0.05. No differences were observed in lipids and C-peptide. Most MODY cases in Brazil are due to GCK mutations. In agreement with other studied populations, novel mutations are common. Only 14% of patients with familial diabetes carry a HNF1A mutation. Diagnosis of other rare forms of MODY is still a challenge in Brazilian population, as well as adequate strategies to screen individuals for molecular diagnosis. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  16. Range extensions of three crayfishes (Faxonius yanahlindus, F. placidus, and F. erichsonianus) into Mississippi

    Treesearch

    Susan B. Adams; Robert L. Jones

    2018-01-01

    We report 3 new state crayfish records from the Tennessee River drainage in Tishomingo County, Mississippi: 1 is a re-identification of previously published material, and 2 are from unpublished collections. Faxonius yanahlindus (Spinywrist Crayfish), recently described from the middle Tennessee River drainage in northwest Alabama and southern...

  17. [Austrian Low Countries, Europe's animal health pioneer, 1769-1776].

    PubMed

    Vallat, F

    2006-12-01

    Two previously unpublished manuscripts reveal how innovative the Austrian Low Countries were when they introduced an animal health policy to control rinderpest in 1769. The policy was novel in that it replaced the slaughter of individual sick animals with herd slaughter. Unfortunately, a number of neighbouring countries failed to emulate this sure-fire method of controlling rinderpest, among them France.

  18. The Driver Behaviour Questionnaire as accident predictor; A methodological re-meta-analysis.

    PubMed

    Af Wåhlberg, A E; Barraclough, P; Freeman, J

    2015-12-01

    The Manchester Driver Behaviour Questionnaire (DBQ) is the most commonly used self-report tool in traffic safety research and applied settings. It has been claimed that the violation factor of this instrument predicts accident involvement, which was supported by a previous meta-analysis. However, that analysis did not test for methodological effects, or include unpublished results. The present study re-analysed studies on prediction of accident involvement from DBQ factors, including lapses, and many unpublished effects. Tests of various types of dissemination bias and common method variance were undertaken. Outlier analysis showed that some effects were probably not reliable data, but excluding them did not change the results. For correlations between violations and crashes, tendencies for published effects to be larger than unpublished ones and for effects to decrease over time were observed, but were not significant. Also, using the mean of accidents as proxy for effect indicated that studies where effects for violations are not reported have smaller effect sizes. These differences indicate dissemination bias. Studies using self-reported accidents as dependent variables had much larger effects than those using recorded accident data. Also, zero-order correlations were larger than partial correlations controlled for exposure. Similarly, violations/accidents effects were strong only when there was also a strong correlation between accidents and exposure. Overall, the true effect is probably very close to zero (r<.07) for violations versus traffic accident involvement, depending upon which tendencies are controlled for. Methodological factors and dissemination bias have inflated the published effect sizes of the DBQ. Strong evidence of various artefactual effects is apparent. A greater level of care should be taken if the DBQ continues to be used in traffic safety research. Also, validation of self-reports should be more comprehensive in the future, taking into account the possibility of common method variance. Copyright © 2015 Elsevier Ltd and National Safety Council. All rights reserved.

  19. Metaphor and Pedagogy in Early Buddhist Literature: An Edition and Study of Two Sutras from the Senior Collection of Gandhari Manuscripts

    ERIC Educational Resources Information Center

    Marino, Joseph

    2017-01-01

    This dissertation examines the role of metaphorical language in early Buddhist literature through the lens of two previously unpublished Gandhari sutras on a manuscript from the Robert Senior Collection. At the microscopic level, I offer an edition, translation, and textual analysis of a Buddhist manuscript containing two Sa?yuktagama-type sutras…

  20. 12 CFR 510.5 - Release of unpublished OTS information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... parties to lawsuits in which the OTS is not a party. (2) Unpublished OTS information includes records created or obtained in connection with the OTS's performance of its responsibilities, such as records... affiliates, and records compiled in connection with the OTS's enforcement responsibilities. Unpublished OTS...

  1. 12 CFR 510.5 - Release of unpublished OTS information.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... parties to lawsuits in which the OTS is not a party. (2) Unpublished OTS information includes records created or obtained in connection with the OTS's performance of its responsibilities, such as records... affiliates, and records compiled in connection with the OTS's enforcement responsibilities. Unpublished OTS...

  2. Four of Ogden Lindsley's Unpublished Presentation Summaries

    ERIC Educational Resources Information Center

    Starlin, Clay M.

    2010-01-01

    As one might expect from the founder of Precision Teaching, Ogden Lindsley was precise in creating the summaries of his presentations. Ogden took the opportunity to share his latest thinking on a topic in his presentations. However, because the presentation summaries have not been published, many people have missed the advantage of this knowledge.…

  3. The Predatory Bird Monitoring Scheme: identifying chemical risks to top predators in Britain.

    PubMed

    Walker, Lee A; Shore, Richard F; Turk, Anthony; Pereira, M Glória; Best, Jennifer

    2008-09-01

    The Predatory Bird Monitoring Scheme (PBMS) is a long term (>40 y), UK-wide, exposure monitoring scheme that determines the concentration of selected pesticides and pollutants in the livers and eggs of predatory birds. This paper describes how the PBMS works, and in particular highlights some of the key scientific and policy drivers for monitoring contaminants in predatory birds and describes the specific aims, scope, and methods of the PBMS. We also present previously unpublished data that illustrates how the PBMS has been used to demonstrate the success of mitigation measures in reversing chemical-mediated impacts; identify and evaluate chemical threats to species of high conservation value; and finally to inform and refine monitoring methodologies. In addition, we discuss how such schemes can also address wider conservation needs.

  4. Professional relationships in dangerous times: C. G. Jung and the Society for Psychotherapy.

    PubMed

    Lammers, Ann C

    2012-02-01

    Relying in part on previously unpublished documents of the 1930s, this paper(1) describes the origins and mission of the General Medical Society for Psychotherapy, both as it existed before Hitler's rise to power and as it was transformed afterward. Jung accepted the Society's presidency in 1933-34, on condition that it be restructured as an international, politically neutral organization, free from the laws of Gleichschaltung (Nazi conformity). The paper also contains a close study of Jung's collaboration with one interesting German colleague, Walter Cimbal. Cimbal, a neurologist, was briefly a member of the Nazi Party and, judging from his early letters to Jung, a Hitler enthusiast. Yet he also seems to have tried, together with Jung, to alleviate the difficulties of German Jewish colleagues whose lives were disrupted by the Hitler revolution. The paper includes translated passages from Cimbal's previously unpublished letters from 1933-36 and the post-war years. It also includes a first-person account by Wladimir Rosenbaum, the Zurich lawyer who assisted Jung in 1934, when Jung tried to mitigate the impact of anti-Jewish laws on his German Jewish colleagues. In the primary materials of this period one discovers more evidence of moral shadow-and also less-than is sometimes assumed. © 2012, The Society of Analytical Psychology.

  5. 12 CFR 911.3 - Prohibition on unauthorized use and disclosure of unpublished information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of unpublished information. 911.3 Section 911.3 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.3... information does not constitute a waiver by the Finance Board of any privilege or its right to control...

  6. 12 CFR 510.5 - Release of unpublished OTS information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 6 2012-01-01 2012-01-01 false Release of unpublished OTS information. 510.5 Section 510.5 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY MISCELLANEOUS ORGANIZATIONAL REGULATIONS § 510.5 Release of unpublished OTS information. (a) Scope. (1) This section applies to...

  7. 12 CFR 911.4 - Requests for unpublished information by document or testimony.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Requests for unpublished information by document or testimony. 911.4 Section 911.4 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.4 Requests for...

  8. 12 CFR 911.4 - Requests for unpublished information by document or testimony.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Requests for unpublished information by document or testimony. 911.4 Section 911.4 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.4 Requests for...

  9. 12 CFR 911.3 - Prohibition on unauthorized use and disclosure of unpublished information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Prohibition on unauthorized use and disclosure of unpublished information. 911.3 Section 911.3 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.3...

  10. 12 CFR 911.4 - Requests for unpublished information by document or testimony.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Requests for unpublished information by document or testimony. 911.4 Section 911.4 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.4 Requests for...

  11. 12 CFR 911.4 - Requests for unpublished information by document or testimony.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Requests for unpublished information by document or testimony. 911.4 Section 911.4 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.4 Requests for...

  12. 12 CFR 911.3 - Prohibition on unauthorized use and disclosure of unpublished information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Prohibition on unauthorized use and disclosure of unpublished information. 911.3 Section 911.3 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.3...

  13. Using ClinicalTrials.gov to supplement information in ophthalmology conference abstracts about trial outcomes: a comparison study.

    PubMed

    Scherer, Roberta W; Huynh, Lynn; Ervin, Ann-Margret; Dickersin, Kay

    2015-01-01

    Including results from unpublished randomized controlled trials (RCTs) in a systematic review may ameliorate the effect of publication bias in systematic review results. Unpublished RCTs are sometimes described in abstracts presented at conferences, included in trials registers, or both. Trial results may not be available in a trials register and abstracts describing RCT results often lack study design information. Complementary information from a trials register record may be sufficient to allow reliable inclusion of an unpublished RCT only available as an abstract in a systematic review. We identified 496 abstracts describing RCTs presented at the 2007 to 2009 Association for Research in Vision and Ophthalmology (ARVO) meetings; 154 RCTs were registered in ClinicalTrials.gov. Two persons extracted verbatim primary and non-primary outcomes reported in the abstract and ClinicalTrials.gov record. We compared each abstract outcome with all ClinicalTrials.gov outcomes and coded matches as complete, partial, or no match. We identified 800 outcomes in 152 abstracts (95 primary [51 abstracts] and 705 [141 abstracts] non-primary outcomes). No outcomes were reported in 2 abstracts. Of 95 primary outcomes, 17 (18%) agreed completely, 53 (56%) partially, and 25 (26%) had no match with a ClinicalTrials.gov primary or non-primary outcome. Among 705 non-primary outcomes, 56 (8%) agreed completely, 205 (29%) agreed partially, and 444 (63%) had no match with a ClinicalTrials.gov primary or non-primary outcome. Among the 258 outcomes partially agreeing, we found additional information on the time when the outcome was measured more often in ClinicalTrials.gov than in the abstract (141/258 (55%) versus 55/258 (21%)). We found no association between the presence of non-matching "new" outcomes and year of registration, time to registry update, industry sponsorship, or multi-center status. Conference abstracts may be a valuable source of information about results for outcomes of unpublished RCTs that have been registered in ClinicalTrials.gov. Complementary additional descriptive information may be present for outcomes reported in both sources. However, ARVO abstract authors also present outcomes not reported in ClinicalTrials.gov and these may represent analyses not originally planned.

  14. Reporting of Adverse Events in Published and Unpublished Studies of Health Care Interventions: A Systematic Review

    PubMed Central

    Golder, Su; Wright, Kath

    2016-01-01

    Background We performed a systematic review to assess whether we can quantify the underreporting of adverse events (AEs) in the published medical literature documenting the results of clinical trials as compared with other nonpublished sources, and whether we can measure the impact this underreporting has on systematic reviews of adverse events. Methods and Findings Studies were identified from 15 databases (including MEDLINE and Embase) and by handsearching, reference checking, internet searches, and contacting experts. The last database searches were conducted in July 2016. There were 28 methodological evaluations that met the inclusion criteria. Of these, 9 studies compared the proportion of trials reporting adverse events by publication status. The median percentage of published documents with adverse events information was 46% compared to 95% in the corresponding unpublished documents. There was a similar pattern with unmatched studies, for which 43% of published studies contained adverse events information compared to 83% of unpublished studies. A total of 11 studies compared the numbers of adverse events in matched published and unpublished documents. The percentage of adverse events that would have been missed had each analysis relied only on the published versions varied between 43% and 100%, with a median of 64%. Within these 11 studies, 24 comparisons of named adverse events such as death, suicide, or respiratory adverse events were undertaken. In 18 of the 24 comparisons, the number of named adverse events was higher in unpublished than published documents. Additionally, 2 other studies demonstrated that there are substantially more types of adverse events reported in matched unpublished than published documents. There were 20 meta-analyses that reported the odds ratios (ORs) and/or risk ratios (RRs) for adverse events with and without unpublished data. Inclusion of unpublished data increased the precision of the pooled estimates (narrower 95% confidence intervals) in 15 of the 20 pooled analyses, but did not markedly change the direction or statistical significance of the risk in most cases. The main limitations of this review are that the included case examples represent only a small number amongst thousands of meta-analyses of harms and that the included studies may suffer from publication bias, whereby substantial differences between published and unpublished data are more likely to be published. Conclusions There is strong evidence that much of the information on adverse events remains unpublished and that the number and range of adverse events is higher in unpublished than in published versions of the same study. The inclusion of unpublished data can also reduce the imprecision of pooled effect estimates during meta-analysis of adverse events. PMID:27649528

  15. Homocysteine and Coronary Heart Disease: Meta-analysis of MTHFR Case-Control Studies, Avoiding Publication Bias

    PubMed Central

    Verhoef, Petra; Dötsch-Klerk, Mariska; Lathrop, Mark; Xu, Peng; Nordestgaard, Børge G.; Holm, Hilma; Hopewell, Jemma C.; Saleheen, Danish; Tanaka, Toshihiro; Anand, Sonia S.; Chambers, John C.; Kleber, Marcus E.; Ouwehand, Willem H.; Yamada, Yoshiji; Elbers, Clara; Peters, Bas; Stewart, Alexandre F. R.; Reilly, Muredach M.; Thorand, Barbara; Yusuf, Salim; Engert, James C.; Assimes, Themistocles L.; Kooner, Jaspal; Danesh, John; Watkins, Hugh; Samani, Nilesh J.

    2012-01-01

    Background Moderately elevated blood levels of homocysteine are weakly correlated with coronary heart disease (CHD) risk, but causality remains uncertain. When folate levels are low, the TT genotype of the common C677T polymorphism (rs1801133) of the methylene tetrahydrofolate reductase gene (MTHFR) appreciably increases homocysteine levels, so “Mendelian randomization” studies using this variant as an instrumental variable could help test causality. Methods and Findings Nineteen unpublished datasets were obtained (total 48,175 CHD cases and 67,961 controls) in which multiple genetic variants had been measured, including MTHFR C677T. These datasets did not include measurements of blood homocysteine, but homocysteine levels would be expected to be about 20% higher with TT than with CC genotype in the populations studied. In meta-analyses of these unpublished datasets, the case-control CHD odds ratio (OR) and 95% CI comparing TT versus CC homozygotes was 1.02 (0.98–1.07; p = 0.28) overall, and 1.01 (0.95–1.07) in unsupplemented low-folate populations. By contrast, in a slightly updated meta-analysis of the 86 published studies (28,617 CHD cases and 41,857 controls), the OR was 1.15 (1.09–1.21), significantly discrepant (p = 0.001) with the OR in the unpublished datasets. Within the meta-analysis of published studies, the OR was 1.12 (1.04–1.21) in the 14 larger studies (those with variance of log OR<0.05; total 13,119 cases) and 1.18 (1.09–1.28) in the 72 smaller ones (total 15,498 cases). Conclusions The CI for the overall result from large unpublished datasets shows lifelong moderate homocysteine elevation has little or no effect on CHD. The discrepant overall result from previously published studies reflects publication bias or methodological problems. Please see later in the article for the Editors' Summary PMID:22363213

  16. Eye injuries from electrical weapon probes: Incidents, prevalence, and legal implications.

    PubMed

    Kroll, Mark W; Ritter, Mollie B; Kennedy, Eric A; Silverman, Nora K; Shinder, Roman; Brave, Michael A; Williams, Howard E

    2018-04-01

    While generally reducing morbidity and mortality, electrical weapons have risks associated with their usage, including burn injuries and trauma associated with uncontrolled fall impacts. However, the prevalence of significant eye injury has not been investigated. We searched for incidents of penetrating eye injury from TASER ® conducted electrical weapon (CEW) probes via open source media, litigation filings, and a survey of CEW law-enforcement master instructors. We report 20 previously-unpublished cases of penetrating eye injury from electrical weapon probes in law-enforcement field uses. Together with the 8 previously published cases, there are a total of 28 cases out of 3.44 million field uses, giving a demonstrated CEW field-use risk of penetrating eye injury of approximately 1:123 000. Confidence limits [85 000, 178 000] by Wilson score interval. There have been 18 cases of total unilateral blindness or enucleation. We also present legal decisions on this topic. The use of electrical weapons presents a rare but real risk of total or partial unilateral blindness from electrical weapon probes. Catastrophic eye injuries appear to be the dominant non-fatal complication of electronic control. Copyright © 2018 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  17. Expediting Combinatorial Data Set Analysis by Combining Human and Algorithmic Analysis.

    PubMed

    Stein, Helge Sören; Jiao, Sally; Ludwig, Alfred

    2017-01-09

    A challenge in combinatorial materials science remains the efficient analysis of X-ray diffraction (XRD) data and its correlation to functional properties. Rapid identification of phase-regions and proper assignment of corresponding crystal structures is necessary to keep pace with the improved methods for synthesizing and characterizing materials libraries. Therefore, a new modular software called htAx (high-throughput analysis of X-ray and functional properties data) is presented that couples human intelligence tasks used for "ground-truth" phase-region identification with subsequent unbiased verification by an algorithm to efficiently analyze which phases are present in a materials library. Identified phases and phase-regions may then be correlated to functional properties in an expedited manner. For the functionality of htAx to be proven, two previously published XRD benchmark data sets of the materials systems Al-Cr-Fe-O and Ni-Ti-Cu are analyzed by htAx. The analysis of ∼1000 XRD patterns takes less than 1 day with htAx. The proposed method reliably identifies phase-region boundaries and robustly identifies multiphase structures. The method also addresses the problem of identifying regions with previously unpublished crystal structures using a special daisy ternary plot.

  18. 12 CFR 911.6 - Persons and entities with access to unpublished information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 8 2013-01-01 2013-01-01 false Persons and entities with access to unpublished information. 911.6 Section 911.6 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.6 Persons and entities with access to...

  19. 12 CFR 911.6 - Persons and entities with access to unpublished information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 7 2011-01-01 2011-01-01 false Persons and entities with access to unpublished information. 911.6 Section 911.6 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.6 Persons and entities with access to...

  20. 12 CFR 911.6 - Persons and entities with access to unpublished information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Persons and entities with access to unpublished information. 911.6 Section 911.6 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.6 Persons and entities with access to...

  1. 12 CFR 911.6 - Persons and entities with access to unpublished information.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 8 2012-01-01 2012-01-01 false Persons and entities with access to unpublished information. 911.6 Section 911.6 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOUSING FINANCE BOARD ORGANIZATION AND OPERATIONS AVAILABILITY OF UNPUBLISHED INFORMATION § 911.6 Persons and entities with access to...

  2. Use of ICT and its Relationship with Performance in Examinations: A Comparison of the ImpaCT2 Project's Research Findings Using Pupil-Level, School-Level and Multilevel Modelling Data

    ERIC Educational Resources Information Center

    Harrison, Colin; Lunzer, Eric A.; Tymms, Peter; Fitz-Gibbon, Carol Taylor; Restorick, Jane

    2004-01-01

    This paper reports a previously unpublished comparative analysis of data from the ImpaCT2 study investigating the relationship between students' performance in England on national tests and their reported use of information technology (particularly networked technology) for school work, at three age levels (11, 14 and 16), in English, Maths and…

  3. Exercise and Bone Density: Meta-Analysis

    DTIC Science & Technology

    2003-10-01

    were estimat- included in our analysis. Thus, for example, if BMD ed using previously developed methods .ŕ T- was also assessed in women performing...from 12.6% unpublished work is inappropriate because it has in the placebo group to 9.0% in the alendronate not gone through the peer review process...Olkin I. Statistical Methods for Meta-Analy- taken that could enhance BMD, cigarette smoking, 0 sis. San Diego, CA: Academic Press; 1985. take tht

  4. Nevitt Sanford: Gentle Prophet, Jeffersonian Rebel.

    ERIC Educational Resources Information Center

    Canon, Harry J.

    1988-01-01

    Presents material from a three-hour interview with Nevitt Sanford and from as yet unpublished personal papers of Sanford's, in which he reminisces about his development as a social scientist, civil libertarian, and humanist. (Author/NB)

  5. Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma.

    PubMed

    Law, Matthew H; Bishop, D Timothy; Lee, Jeffrey E; Brossard, Myriam; Martin, Nicholas G; Moses, Eric K; Song, Fengju; Barrett, Jennifer H; Kumar, Rajiv; Easton, Douglas F; Pharoah, Paul D P; Swerdlow, Anthony J; Kypreou, Katerina P; Taylor, John C; Harland, Mark; Randerson-Moor, Juliette; Akslen, Lars A; Andresen, Per A; Avril, Marie-Françoise; Azizi, Esther; Scarrà, Giovanna Bianchi; Brown, Kevin M; Dębniak, Tadeusz; Duffy, David L; Elder, David E; Fang, Shenying; Friedman, Eitan; Galan, Pilar; Ghiorzo, Paola; Gillanders, Elizabeth M; Goldstein, Alisa M; Gruis, Nelleke A; Hansson, Johan; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Ingvar, Christian; Kanetsky, Peter A; Chen, Wei V; Landi, Maria Teresa; Lang, Julie; Lathrop, G Mark; Lubiński, Jan; Mackie, Rona M; Mann, Graham J; Molven, Anders; Montgomery, Grant W; Novaković, Srdjan; Olsson, Håkan; Puig, Susana; Puig-Butille, Joan Anton; Qureshi, Abrar A; Radford-Smith, Graham L; van der Stoep, Nienke; van Doorn, Remco; Whiteman, David C; Craig, Jamie E; Schadendorf, Dirk; Simms, Lisa A; Burdon, Kathryn P; Nyholt, Dale R; Pooley, Karen A; Orr, Nick; Stratigos, Alexander J; Cust, Anne E; Ward, Sarah V; Hayward, Nicholas K; Han, Jiali; Schulze, Hans-Joachim; Dunning, Alison M; Bishop, Julia A Newton; Demenais, Florence; Amos, Christopher I; MacGregor, Stuart; Iles, Mark M

    2015-09-01

    Thirteen common susceptibility loci have been reproducibly associated with cutaneous malignant melanoma (CMM). We report the results of an international 2-stage meta-analysis of CMM genome-wide association studies (GWAS). This meta-analysis combines 11 GWAS (5 previously unpublished) and a further three stage 2 data sets, totaling 15,990 CMM cases and 26,409 controls. Five loci not previously associated with CMM risk reached genome-wide significance (P < 5 × 10(-8)), as did 2 previously reported but unreplicated loci and all 13 established loci. Newly associated SNPs fall within putative melanocyte regulatory elements, and bioinformatic and expression quantitative trait locus (eQTL) data highlight candidate genes in the associated regions, including one involved in telomere biology.

  6. Genome-wide meta-analysis identifies five new susceptibility loci for cutaneous malignant melanoma

    PubMed Central

    Law, Matthew H.; Bishop, D. Timothy; Martin, Nicholas G.; Moses, Eric K.; Song, Fengju; Barrett, Jennifer H.; Kumar, Rajiv; Easton, Douglas F.; Pharoah, Paul D. P.; Swerdlow, Anthony J.; Kypreou, Katerina P.; Taylor, John C.; Harland, Mark; Randerson-Moor, Juliette; Akslen, Lars A.; Andresen, Per A.; Avril, Marie-Françoise; Azizi, Esther; Scarrà, Giovanna Bianchi; Brown, Kevin M.; Dębniak, Tadeusz; Duffy, David L.; Elder, David E.; Fang, Shenying; Friedman, Eitan; Galan, Pilar; Ghiorzo, Paola; Gillanders, Elizabeth M.; Goldstein, Alisa M.; Gruis, Nelleke A.; Hansson, Johan; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Ingvar, Christian; Kanetsky, Peter A.; Chen, Wei V.; Landi, Maria Teresa; Lang, Julie; Lathrop, G. Mark; Lubiński, Jan; Mackie, Rona M.; Mann, Graham J.; Molven, Anders; Montgomery, Grant W.; Novaković, Srdjan; Olsson, Håkan; Puig, Susana; Puig-Butille, Joan Anton; Qureshi, Abrar A.; Radford-Smith, Graham L.; van der Stoep, Nienke; van Doorn, Remco; Whiteman, David C.; Craig, Jamie E.; Schadendorf, Dirk; Simms, Lisa A.; Burdon, Kathryn P.; Nyholt, Dale R.; Pooley, Karen A.; Orr, Nick; Stratigos, Alexander J.; Cust, Anne E.; Ward, Sarah V.; Hayward, Nicholas K.; Han, Jiali; Schulze, Hans-Joachim; Dunning, Alison M.; Bishop, Julia A. Newton; MacGregor, Stuart; Iles, Mark M.

    2015-01-01

    Thirteen common susceptibility loci have been reproducibly associated with cutaneous malignant melanoma (CMM). We report the results of an international 2-stage meta-analysis of CMM genome-wide association studies (GWAS). This meta-analysis combines 11 GWAS (5 previously unpublished) and a further three stage 2 data sets, totaling 15,990 CMM cases and 26,409 controls. Five loci not previously associated with CMM risk reached genome-wide significance (P < 5×10–8), as did two previously-reported but un-replicated loci and all thirteen established loci. Novel SNPs fall within putative melanocyte regulatory elements, and bioinformatic and expression quantitative trait locus (eQTL) data highlight candidate genes including one involved in telomere biology. PMID:26237428

  7. Security Analysis and Improvement of an Anonymous Authentication Scheme for Roaming Services

    PubMed Central

    Lee, Youngsook; Paik, Juryon

    2014-01-01

    An anonymous authentication scheme for roaming services in global mobility networks allows a mobile user visiting a foreign network to achieve mutual authentication and session key establishment with the foreign-network operator in an anonymous manner. In this work, we revisit He et al.'s anonymous authentication scheme for roaming services and present previously unpublished security weaknesses in the scheme: (1) it fails to provide user anonymity against any third party as well as the foreign agent, (2) it cannot protect the passwords of mobile users due to its vulnerability to an offline dictionary attack, and (3) it does not achieve session-key security against a man-in-the-middle attack. We also show how the security weaknesses of He et al.'s scheme can be addressed without degrading the efficiency of the scheme. PMID:25302330

  8. Security analysis and improvement of an anonymous authentication scheme for roaming services.

    PubMed

    Lee, Youngsook; Paik, Juryon

    2014-01-01

    An anonymous authentication scheme for roaming services in global mobility networks allows a mobile user visiting a foreign network to achieve mutual authentication and session key establishment with the foreign-network operator in an anonymous manner. In this work, we revisit He et al.'s anonymous authentication scheme for roaming services and present previously unpublished security weaknesses in the scheme: (1) it fails to provide user anonymity against any third party as well as the foreign agent, (2) it cannot protect the passwords of mobile users due to its vulnerability to an offline dictionary attack, and (3) it does not achieve session-key security against a man-in-the-middle attack. We also show how the security weaknesses of He et al.'s scheme can be addressed without degrading the efficiency of the scheme.

  9. Fatal tiger shark, Galeocerdo cuvier attack in New Caledonia erroneously ascribed to great white shark, Carcharodon carcharias.

    PubMed

    Tirard, Philippe; Maillaud, Claude; Borsa, Philippe

    2015-07-01

    To understand the causes and patterns of shark attacks on humans, accurate identification of the shark species involved is necessary. Often, the only reliable evidence for this comes from the characteristics of the wounds exhibited by the victim. The present case report is intended as a reappraisal of the Luengoni, 2007 case (International Shark Attack File no. 4299) where a single shark bite provoked the death of a swimmer by haemorrhagic shock. Our examination of the wounds on the body of the victim, here documented by so-far unpublished photographic evidence, determined that the shark possessed large and homodontous jaws. This demonstrates that the attacker was a tiger shark, not a great white shark as previously published. Copyright © 2015 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

  10. Collected Papers on Wind Turbine Technology

    NASA Technical Reports Server (NTRS)

    Spera, David A. (Editor)

    1995-01-01

    R and D projects on electricity generating wind turbines were conducted at the NASA Lewis Research Center from 1973 to 1988. Most projects were sponsored by the U.S. Department of Energy (DOE), a major element of its Federal Wind Energy Program. Another large wind turbine project was by the Bureau of Reclamation of the U.S. Department of Interior (DOI). From 1988 to 1995, NASA wind energy activities have been directed toward the transfer of technology to commercial and academic organizations. As part of these technology transfer activities, previously unpublished manuscripts have been assembled and presented here to share the wind turbine research results with the wind energy community. A variety of wind turbine technology topics are discussed: Wind and wake models; Airfoil properties; Structural analysis and testing; Control systems; Variable speed generators; and acoustic noise. Experimental and theoretical results are discussed.

  11. MoFvAb: Modeling the Fv region of antibodies

    PubMed Central

    Bujotzek, Alexander; Fuchs, Angelika; Qu, Changtao; Benz, Jörg; Klostermann, Stefan; Antes, Iris; Georges, Guy

    2015-01-01

    Knowledge of the 3-dimensional structure of the antigen-binding region of antibodies enables numerous useful applications regarding the design and development of antibody-based drugs. We present a knowledge-based antibody structure prediction methodology that incorporates concepts that have arisen from an applied antibody engineering environment. The protocol exploits the rich and continuously growing supply of experimentally derived antibody structures available to predict CDR loop conformations and the packing of heavy and light chain quickly and without user intervention. The homology models are refined by a novel antibody-specific approach to adapt and rearrange sidechains based on their chemical environment. The method achieves very competitive all-atom root mean square deviation values in the order of 1.5 Å on different evaluation datasets consisting of both known and previously unpublished antibody crystal structures. PMID:26176812

  12. Goddard Laboratory for Atmospheric Sciences physical retrieval system for remote determination of weather and climate parameter from HIRS2 and MSU observations

    NASA Technical Reports Server (NTRS)

    Susskind, J.

    1984-01-01

    At the Goddard Laboratory for Atmospheric Sciences (GLAS) a physically based satellite temperature sounding retrieval system, involving the simultaneous analysis of HIRS2 and MSU sounding data, was developed for determining atmospheric and surface conditions which are consistent with the observed radiances. In addition to determining accurate atmospheric temperature profiles even in the presence of cloud contamination, the system provides global estimates of day and night sea or land surface temperatures, snow and ice cover, and parameters related to cloud cover. Details of the system are described elsewhere. A brief overview of the system is presented, as well as recent improvements and previously unpublished results, relating to the sea-surface intercomparison workshop, the diurnal variation of ground temperatures, and forecast impact tests.

  13. Summary of Round Table Session and Appendixes

    Treesearch

    1992-01-01

    The round table session was designed for interaction between the presenters and other round table participants. Twelve round tables, each capable of holding 10 participants were set up in one room. Presenters for the sessions were encouraged to lead discussions on one of many topics in these areas: a research idea that the presenter was just formulating; an unpublished...

  14. A compilation of K-Ar-ages for southern California

    USGS Publications Warehouse

    Miller, Fred K.; Morton, Douglas M.; Morton, Janet L.; Miller, David M.

    2014-01-01

    The purpose of this report is to make available a large body of conventional K-Ar ages for granitic, volcanic, and metamorphic rocks collected in southern California. Although one interpretive map is included, the report consists primarily of a systematic listing, without discussion or interpretation, of published and unpublished ages that may be of value in future regional and other geologic studies. From 1973 to 1979, 468 rock samples from southern California were collected for conventional K-Ar dating under a regional geologic mapping project of Southern California (predecessor of the Southern California Areal Mapping Project). Most samples were collected and dated between 1974 and 1977. For 61 samples (13 percent of those collected), either they were discarded for varying reasons, or the original collection data were lost. For the remaining samples, 518 conventional K-Ar ages are reported here; coexisting mineral pairs were dated from many samples. Of these K-Ar ages, 225 are previously unpublished, and identified as such in table 1. All K-Ar ages are by conventional K-Ar analysis; no 40Ar/39Ar dating was done. Subsequent to the rock samples collected in the 1970s and reported here, 33 samples were collected and 38 conventional K-Ar ages determined under projects directed at (1) characterization of the Mesozoic and Cenozoic igneous rocks in and on both sides of the Transverse Ranges and (2) clarifying the Mesozoic and Cenozoic tectonics of the eastern Mojave Desert. Although previously published (Beckerman et al., 1982), another eight samples and 11 conventional K-Ar ages are included here, because they augment those completed under the previous two projects.

  15. How to search for and use 'grey literature' in research.

    PubMed

    Coad, Jane; Hardicre, Jayne; Devitt, Patric

    An ever-growing amount of grey literature is available to nurses, including oral presentations, personal communication, leaflets, newspapers and magazines, unpublished research, internal reports and minutes of meetings. It can be an invaluable research resource.

  16. [Not Available].

    PubMed

    Gourevitch, Danielle

    2016-01-01

    After a paper by Jacques Chevallier (Histoire des sciences médicales, XLIX, 2015, 179-188), the author presents two unpublished letters from Engène Brieux, a popular write, and amateur of cruises, to Dr. Édouard Toulouse, a famous psychiatrist.

  17. More evidence of unpublished industry studies of lead smelter/refinery workers.

    PubMed

    Sullivan, Marianne

    2015-01-01

    Lead smelter/refinery workers in the US have had significant exposure to lead and are an important occupational group to study to understand the health effects of chronic lead exposure in adults. Recent research found evidence that studies of lead smelter/refinery workers have been conducted but not published. This paper presents further evidence for this contention. To present further evidence of industry conducted, unpublished epidemiologic studies of lead smelter/refinery workers and health outcomes. Historical research relying on primary sources such as internal industry documents and published studies. ASARCO smelter/refinery workers were studied in the early 1980s and found to have increased risk of lung cancer and stroke in one study, but not in another. Because occupational lead exposure is an on-going concern for US and overseas workers, all epidemiologic studies should be made available to evaluate and update occupational health and safety standards.

  18. More evidence of unpublished industry studies of lead smelter/refinery workers

    PubMed Central

    2015-01-01

    Background Lead smelter/refinery workers in the US have had significant exposure to lead and are an important occupational group to study to understand the health effects of chronic lead exposure in adults. Recent research found evidence that studies of lead smelter/refinery workers have been conducted but not published. This paper presents further evidence for this contention. Objectives To present further evidence of industry conducted, unpublished epidemiologic studies of lead smelter/refinery workers and health outcomes. Methods Historical research relying on primary sources such as internal industry documents and published studies. Results ASARCO smelter/refinery workers were studied in the early 1980s and found to have increased risk of lung cancer and stroke in one study, but not in another. Conclusions Because occupational lead exposure is an on-going concern for US and overseas workers, all epidemiologic studies should be made available to evaluate and update occupational health and safety standards. PMID:26070220

  19. Copyright and Related Issues Relevant to Digital Preservation and Dissemination of Unpublished Pre-1972 Sound Recordings by Libraries and Archives. CLIR Publication No. 144

    ERIC Educational Resources Information Center

    Besek, June M.

    2009-01-01

    This report addresses the question of what libraries and archives are legally empowered to do to preserve and make accessible for research their holdings of unpublished pre-1972 sound recordings. The report's author, June M. Besek, is executive director of the Kernochan Center for Law, Media and the Arts at Columbia Law School. Unpublished sound…

  20. Documentation for the machine-readable version of the Henry Draper Catalogue (edition 1985)

    NASA Technical Reports Server (NTRS)

    Roman, N. G.; Warren, W. H., Jr.

    1985-01-01

    An updated, corrected and extended machine-readable version of the catalog is described. Published and unpublished errors discovered in the previous version was corrected; letters indicating supplemental stars in the BD have been moved to a new byte to distinguish them from double-star components; and the machine readable portion of The Henry Draper Extension (HDE) (HA 100) was converted to the same format as the main catalog, with additional data added as necessary.

  1. The Role of Second Phase Intermetallic Particles on the Spall Failure of 5083 Aluminum

    DTIC Science & Technology

    2016-12-01

    of mechanically processed 5083 aluminum (i.e., cold and hot rolled, extruded , etc.) has been previously studied by several researchers [1–4]. Results...Velocity Interferometry System for Any Reflector (VISAR) [6]. In addition, four end-state (ex situ spall recovery) experiments were conducted to augment all... extruded AMX602 Mg alloy (unpublished) J. dynamic behavior mater. (2016) 2:476–483 483 123 9 1 DEFENSE TECHNICAL (PDF) INFORMATION CTR DTIC OCA

  2. Using a Cultural and RDoC Framework to Conceptualize Anxiety in Asian Americans

    PubMed Central

    Liu, Huiting; Lieberman, Lynne; Stevens, Elizabeth; Auerbach, Randy P.; Shankman, Stewart A.

    2016-01-01

    Asian Americans are one of the fastest growing minority group in the United States; however, mental health within this population segment, particularly anxiety disorders, remains significantly understudied. Both the heterogeneity within the Asian American population, along with the multidimensional nature of anxiety, contribute to difficulties in understanding anxiety in this population. The present paper will review two sources of heterogeneity within anxiety in Asian Americans: (1) cultural variables and (2) mechanisms or components of anxiety. Specifically, we will examine four cultural variables most commonly found in research related to anxiety in Asian Americans: acculturation, affect valuation, loss of face, and individualism-collectivism. We will also discuss ways to parse anxiety through a Research Domain Criteria (RDoC) framework, specifically focusing on sensitivity to acute and potential threat, constructs within the Negative Valence System. We also present previously unpublished preliminary data to illustrate one way of examining ethnic differences in anxiety using an RDoC framework. Finally, this paper offers recommendations for future work in this area. PMID:27659553

  3. The Classification and Prognosis of Periocular Complications Related to Blindness following Cosmetic Filler Injection.

    PubMed

    Myung, Yujin; Yim, Sangjun; Jeong, Jae Hoon; Kim, Baek-Kyu; Heo, Chan-Yeong; Baek, Rong-Min; Pak, Chang-Sik

    2017-07-01

    Common side effects during hyaluronic acid filler injections are typically mild and reversible, but several reports of blindness have received attention. The present study focused on orbital symptoms combined with blindness, aiming to classify affected patients and predict their disease course and prognosis. From September of 2012 to August of 2015, nine patients with vision loss after filler injection were retrospectively reviewed. Ptosis, ophthalmoplegia, and enophthalmos were recorded over a 6-month follow-up, and patients were classified into four types according to periocular symptom manifestation. Two patients were categorized as type I (blindness without ptosis or ophthalmoplegia), two patients as type II (blindness and ptosis without ophthalmoplegia), two patients as type III (blindness and ophthalmoplegia without ptosis), and three patients as type IV (blindness with ptosis and ophthalmoplegia). The present study includes previously unpublished information about orbital symptom manifestations and prognosis combined with blindness caused by retinal artery occlusion after cosmetic filler injection. Therapeutic, V.

  4. Using a cultural and RDoC framework to conceptualize anxiety in Asian Americans.

    PubMed

    Liu, Huiting; Lieberman, Lynne; Stevens, Elizabeth S; Auerbach, Randy P; Shankman, Stewart A

    2017-05-01

    Asian Americans are one of the fastest growing minority groups in the United States; however, mental health within this population segment, particularly anxiety disorders, remains significantly understudied. Both the heterogeneity within the Asian American population and the multidimensional nature of anxiety contribute to difficulties in understanding anxiety in this population. The present paper reviewed two sources of heterogeneity within anxiety in Asian Americans: (1) cultural variables and (2) mechanisms or components of anxiety. Specifically, we examined four cultural variables most commonly found in research related to anxiety in Asian Americans: acculturation, loss of face, affect valuation, and individualism-collectivism. We also discussed ways to parse anxiety through a Research Domain Criteria (RDoC) framework, specifically focusing on sensitivity to acute and potential threat, constructs within the Negative Valence System. Previously unpublished preliminary data were presented to illustrate one way of examining ethnic differences in anxiety using an RDoC framework. Finally, this paper offered recommendations for future work in this area. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Radiofrequency heating pathways for gold nanoparticles.

    PubMed

    Collins, C B; McCoy, R S; Ackerson, B J; Collins, G J; Ackerson, C J

    2014-08-07

    This feature article reviews the thermal dissipation of nanoscopic gold under radiofrequency (RF) irradiation. It also presents previously unpublished data addressing obscure aspects of this phenomenon. While applications in biology motivated initial investigation of RF heating of gold nanoparticles, recent controversy concerning whether thermal effects can be attributed to nanoscopic gold highlight the need to understand the involved mechanism or mechanisms of heating. Both the nature of the particle and the nature of the RF field influence heating. Aspects of nanoparticle chemistry which may affect thermal dissipation include the hydrodynamic diameter of the particle, the oxidation state and related magnetism of the core, and the chemical nature of the ligand shell. Aspects of RF which may affect thermal dissipation include power, frequency and antenna designs that emphasize relative strength of magnetic or electric fields. These nanoparticle and RF properties are analysed in the context of three heating mechanisms proposed to explain gold nanoparticle heating in an RF field. This article also makes a critical analysis of the existing literature in the context of the nanoparticle preparations, RF structure, and suggested mechanisms in previously reported experiments.

  6. Surficial geologic map of the Gates of the Arctic National Park and Preserve, Alaska

    USGS Publications Warehouse

    Hamilton, Thomas D.; Labay, Keith A.

    2011-01-01

    The surfical geologic map incorporates parts of ten surficial geologic maps previously published at 1:250,000 scale. In addition, a small part of the buffer zone mapped in the southwest corner of the map area was compiled from unpublished surficial geologic mapping of the Shungnak 1:250,000-scale quadrangle. Each of those individual maps was developed from (1) aerial and surface observations of morphology and composition of unconsolidated deposits, (2) tracing the distribution and interrelation of terraces, abandoned meltwater channels, moraines, abandoned lake beds, and other landforms, (3) stratigraphic study of exposures along lake shores and river bluffs, (4) examination of sediments and soil profiles in auger borings and test pits, and exposed in roadcuts and placer workings, and (5) analysis of previously published geologic maps and reports. The map units used for those maps and employed in the present compilation are defined on the basis of their physical character, genesis, and age. Relative and absolute ages of the map units were determined from their geographic locations and from their stratigraphic positions and radiocarbon ages.

  7. [Ethnic groups and towns: an analysis of migration toward the towns of the Ivory Coast].

    PubMed

    Marguerat, Y

    1981-01-01

    An analysis of urbanization and internal migration in the Ivory Coast is presented based on unpublished data from the 1975 census. Particular attention is paid to variations in migration by ethnic group.

  8. Towards Reduced Wall Effect Hall Plasma Accelerators

    DTIC Science & Technology

    2007-07-01

    Unpublished Conference Presentations E. Fernandez, N. Borelli , M. Cappelli, N. Gascon, "Investigation of Fluctuation-Induced Electron Transport in Hall...International Electric Propulsion Conference, Princeton University, October 31 November 4, 2005. 38. E. Fernandez, N. Borelli , M. Cappelli, N. Gascon

  9. Using ClinicalTrials.gov to Supplement Information in Ophthalmology Conference Abstracts about Trial Outcomes: A Comparison Study

    PubMed Central

    Scherer, Roberta W.; Huynh, Lynn; Ervin, Ann-Margret; Dickersin, Kay

    2015-01-01

    Background Including results from unpublished randomized controlled trials (RCTs) in a systematic review may ameliorate the effect of publication bias in systematic review results. Unpublished RCTs are sometimes described in abstracts presented at conferences, included in trials registers, or both. Trial results may not be available in a trials register and abstracts describing RCT results often lack study design information. Complementary information from a trials register record may be sufficient to allow reliable inclusion of an unpublished RCT only available as an abstract in a systematic review. Methods We identified 496 abstracts describing RCTs presented at the 2007 to 2009 Association for Research in Vision and Ophthalmology (ARVO) meetings; 154 RCTs were registered in ClinicalTrials.gov. Two persons extracted verbatim primary and non-primary outcomes reported in the abstract and ClinicalTrials.gov record. We compared each abstract outcome with all ClinicalTrials.gov outcomes and coded matches as complete, partial, or no match. Results We identified 800 outcomes in 152 abstracts (95 primary [51 abstracts] and 705 [141 abstracts] non-primary outcomes). No outcomes were reported in 2 abstracts. Of 95 primary outcomes, 17 (18%) agreed completely, 53 (56%) partially, and 25 (26%) had no match with a ClinicalTrials.gov primary or non-primary outcome. Among 705 non-primary outcomes, 56 (8%) agreed completely, 205 (29%) agreed partially, and 444 (63%) had no match with a ClinicalTrials.gov primary or non-primary outcome. Among the 258 outcomes partially agreeing, we found additional information on the time when the outcome was measured more often in ClinicalTrials.gov than in the abstract (141/258 (55%) versus 55/258 (21%)). We found no association between the presence of non-matching “new” outcomes and year of registration, time to registry update, industry sponsorship, or multi-center status. Conclusion Conference abstracts may be a valuable source of information about results for outcomes of unpublished RCTs that have been registered in ClinicalTrials.gov. Complementary additional descriptive information may be present for outcomes reported in both sources. However, ARVO abstract authors also present outcomes not reported in ClinicalTrials.gov and these may represent analyses not originally planned. PMID:26107924

  10. Current Close Air Support Doctrine: Out of Step With New Technology and Urban CAS Requirements

    DTIC Science & Technology

    2001-05-18

    friendly injury from CAS attacks in danger close situations discouraged the use and reduced the effectiveness of CAS. Subsequently, all participants...September 2000. Unpublished Thesis Bell, Steven E. “ Close Air Support for the Future.” Unpublished Research Paper, U.S. Army Command and General Staff...Naval War College, Newport, RI: 2000. Garret, Thomas W. “ Close Air Support: Why All the Fuss?” Unpublished Research Paper, U.S. Army War College

  11. Information Warfare: Issues Associated with the Defense of DOD Computers and Computer Networks

    DTIC Science & Technology

    2002-04-12

    professionals; any mistakes that remain are mine and mine alone. Finally, I wish to thank my family, my wife Cecilia , my daughters Leslie and Marguerite, and my...Accessed 15 January 2002. Malicious Activity Continues to Climb Virus Growth Per Month (Internet - “Wild List”) J a n May NovS e pJul 130 140 150 160...28 Original brief previously unpublished. Briefing is currently held in Operation Directorate ( J -3) of the Joint Task

  12. The amphibians and reptiles of Luzon Island, Philippines, VIII: the herpetofauna of Cagayan and Isabela Provinces, northern Sierra Madre Mountain Range

    PubMed Central

    Brown, Rafe M.; Siler, Cameron D.; Oliveros, Carl. H; Welton, Luke J.; Rock, Ashley; Swab, John; Weerd, Merlijn Van; van Beijnen, Jonah; Jose, Edgar; Rodriguez, Dominic; Jose, Edmund; Diesmos, Arvin C.

    2013-01-01

    Abstract We provide the first report on the herpetological biodiversity (amphibians and reptiles) of the northern Sierra Madre Mountain Range (Cagayan and Isabela provinces), northeast Luzon Island, Philippines. New data from extensive previously unpublished surveys in the Municipalities of Gonzaga, Gattaran, Lasam, Santa Ana, and Baggao (Cagayan Province), as well as fieldwork in the Municipalities of Cabagan, San Mariano, and Palanan (Isabela Province), combined with all available historical museum records, suggest this region is quite diverse. Our new data indicate that at least 101 species are present (29 amphibians, 30 lizards, 35 snakes, two freshwater turtles, three marine turtles, and two crocodilians) and now represented with well-documented records and/or voucher specimens, confirmed in institutional biodiversity repositories. A high percentage of Philippine endemic species constitute the local fauna (approximately 70%). The results of this and other recent studies signify that the herpetological diversity of the northern Philippines is far more diverse than previously imagined. Thirty-eight percent of our recorded species are associated with unresolved taxonomic issues (suspected new species or species complexes in need of taxonomic partitioning). This suggests that despite past and present efforts to comprehensively characterize the fauna, the herpetological biodiversity of the northern Philippines is still substantially underestimated and warranting of further study. PMID:23653519

  13. The amphibians and reptiles of Luzon Island, Philippines, VIII: the herpetofauna of Cagayan and Isabela Provinces, northern Sierra Madre Mountain Range.

    PubMed

    Brown, Rafe M; Siler, Cameron D; Oliveros, Carl H; Welton, Luke J; Rock, Ashley; Swab, John; Weerd, Merlijn Van; van Beijnen, Jonah; Jose, Edgar; Rodriguez, Dominic; Jose, Edmund; Diesmos, Arvin C

    2013-01-01

    We provide the first report on the herpetological biodiversity (amphibians and reptiles) of the northern Sierra Madre Mountain Range (Cagayan and Isabela provinces), northeast Luzon Island, Philippines. New data from extensive previously unpublished surveys in the Municipalities of Gonzaga, Gattaran, Lasam, Santa Ana, and Baggao (Cagayan Province), as well as fieldwork in the Municipalities of Cabagan, San Mariano, and Palanan (Isabela Province), combined with all available historical museum records, suggest this region is quite diverse. Our new data indicate that at least 101 species are present (29 amphibians, 30 lizards, 35 snakes, two freshwater turtles, three marine turtles, and two crocodilians) and now represented with well-documented records and/or voucher specimens, confirmed in institutional biodiversity repositories. A high percentage of Philippine endemic species constitute the local fauna (approximately 70%). The results of this and other recent studies signify that the herpetological diversity of the northern Philippines is far more diverse than previously imagined. Thirty-eight percent of our recorded species are associated with unresolved taxonomic issues (suspected new species or species complexes in need of taxonomic partitioning). This suggests that despite past and present efforts to comprehensively characterize the fauna, the herpetological biodiversity of the northern Philippines is still substantially underestimated and warranting of further study.

  14. New records of Amblyomma goeldii (Acari: Ixodidae) and description of the nymphal stage.

    PubMed

    Martins, Thiago F; Gianizella, Sérgio L; Nunes, Pablo H; Faria, Diogo C L O; Do Nascimento, Carlos A R; Abrahão, Carlos R; Miranda, Flávia R; Teixeira, Rodrigo H F; Ramirez, Diego G; Barros-Battesti, Darci M; Labruna, Marcelo B

    2015-04-29

    Since its original description from the Amazonian region, the tick species Amblyomma goeldii Neumann, 1899 has been misidentified with Amblyomma rotundatum Koch, 1844 in different countries of the Neotropical region. Because of this, some authors have considered that the only confirmed records of A. goeldii were from French Guyana. Herein, we reviewed all specimens of A. goeldii that have been deposited at two tick collections in Brazil. In addition, we describe the nymphal stage of A. goeldii for the first time. A total of 10 unpublished records of the adult stage of A. goeldii are recorded from the Amazonian region of Brazil, confirming the occurrence of A. goeldii in this country. Except for one record on the snake Boa constrictor Linnaeus, all records of A. goeldii reported in the present study were from anteaters (Pilosa: Myrmecophagidae). Our results, in conjunction with previous literature records, indicate that anteaters and large snakes are important hosts for the adult stage of A. goeldii. The nymph of A. goeldii is morphologically similar to the nymphs of Amblyomma romitii Tonelli-Rondelli, 1939, Amblyomma dissimile Koch, 1844, and A. rotundatum. We present a modification of a previously published taxonomic key of Amblyomma nymphs from Brazil, in order to perform taxonomic identification of the nymph of A. goeldii based on external morphology. The geographical distribution of A. goeldii appears to be restricted to the Amazonian region. There were no previous host records for the immature stages of A. goeldii, thus it is expected that the present nymphal description will facilitate further works on the ecology of this poorly studied tick species.

  15. Applying Superresolution Localization-Based Microscopy to Neurons

    PubMed Central

    ZHONG, HAINING

    2016-01-01

    Proper brain function requires the precise localization of proteins and signaling molecules on a nanometer scale. The examination of molecular organization at this scale has been difficult in part because it is beyond the reach of conventional, diffraction-limited light microscopy. The recently developed method of superresolution, localization-based fluorescent microscopy (LBM), such as photoactivated localization microscopy (PALM) and stochastic optical reconstruction microscopy (STORM), has demonstrated a resolving power at a 10 nm scale and is poised to become a vital tool in modern neuroscience research. Indeed, LBM has revealed previously unknown cellular architectures and organizational principles in neurons. Here, we discuss the principles of LBM, its current applications in neuroscience, and the challenges that must be met before its full potential is achieved. We also present the unpublished results of our own experiments to establish a sample preparation procedure for applying LBM to study brain tissue. PMID:25648102

  16. Adolf naef (1883-1949): on foundational concepts and principles of systematic morphology.

    PubMed

    Rieppel, Olivier; Williams, David M; Ebach, Malte C

    2013-01-01

    During the early twentieth century, the Swiss Zoologist Adolf Naef (1883-1949) established himself as a leader in German comparative anatomy and higher level systematics. He is generally labeled an 'idealistic morphologist', although he himself called his research program 'systematic morphology'. The idealistic morphology that flourished in German biology during the first half of the twentieth century was a rather heterogeneous movement, within which Adolf Naef worked out a special theoretical system of his own. Following a biographical sketch, we present an English translation of a previously unpublished typescript from Naef's estate, which Naef intended as the introduction to a textbook on Comparative Anatomy for which he was unable to find a publisher before his sudden death in 1949. The typescript contains Naef's mature thoughts with unprecedented conciseness, focus, and clarity. The density of Naef's text warrants a historical and contextual explication of its content.

  17. Taylor Impact Tests and Simulations on PBX 9501

    NASA Astrophysics Data System (ADS)

    Clements, Brad; Thompson, Darla G.; Luscher, D. J.; Deluca, Racci

    2011-06-01

    Taylor impact tests have been conducted previously on plastic bonded explosives (PBXs) to characterize the stress state of these materials as they impact smooth and flat steel anvil surfaces at speeds of ~100m/s (i.e. Christopher, et al, 11th Detonation Symposium). In 2003, C. Liu and R. Ellis (unpublished, Los Alamos National Laboratory) performed Taylor tests on PBX 9501 up to speeds of 115 m/s, capturing impact images. In the work presented here, we have extended these tests to velocities of 200 m/s using a composite-lined gun barrel and no specimen sabot. Specimen images are used to validate the thermo-mechanical constitutive model ViscoSCRAM. ViscoSCRAM has been parameterized for PBX 9501 in uniaxial stress configurations. Simulating Taylor impact experiments tests the model in situations undergoing extreme damage. In addition, experimental variations to specimen confinement and friction are introduced in an attempt to establish ignition thresholds in this velocity regime.

  18. Ted Hall and the science of biological microprobe X-ray analysis: a historical perspective of methodology and biological dividends.

    PubMed

    Gupta, B L

    1991-06-01

    This review surveys the emergence of electron probe X-ray microanalysis as a quantitative method for measuring the chemical elements in situ. The extension of the method to the biological sciences under the influence of Ted Hall is reviewed. Some classical experiments by Hall and his colleagues in Cambridge, UK, previously unpublished, are described; as are some of the earliest quantitative results from the cryo-sections obtained in Cambridge and elsewhere. The progress of the methodology is critically evaluated from the earliest starts to the present state of the art. Particular attention has been focused on the application of the method in providing fresh insights into the role of ions in cell and tissue physiology and pathology. A comprehensive list of references is included for a further pursuit of the topics by the interested reader.

  19. Percolation behaviour in the magnetic permeability and electrical conductivity in conducting magnetic - Insulating non magnetic binary composites

    NASA Astrophysics Data System (ADS)

    McLachlan, David S.; Doyle, Terence B.; Sauti, Godfrey

    2018-07-01

    Experimental results of the complex magnetic permeability (μ) and the electrical conductivity (σ) of a granular paramagnetic Gadolinium Gallium Garnet (GGG: 0.3-26 vol%) and Teflon (PTFE) system are presented and discussed in relation to previously published (conductivity) and unpublished (permeability) studies on granular Fe3O4 - talc and Ni - talc wax systems. In these systems plots of the real conductivity (σm‧) against the volume fraction (φ) lie on characteristic sigmoid curves that when fitted to the Two Exponent Phenomenological Percolation Equation (TEPPE) confirm the existence of "percolation microstructures" with critical volume fractions (φc). The plots of the real and imaginary permeability (μm‧) and (μm″) satisfactorily fit to the TEPPE using the φc obtained in each case from the "conductivity" measurements. In all three cases the conductivity results gave the exponent t > 2, and the permeability results gave t < 1.

  20. Strategies for obtaining unpublished drug trial data: a qualitative interview study

    PubMed Central

    2013-01-01

    Background Authors of systematic reviews have difficulty obtaining unpublished data for their reviews. This project aimed to provide an in-depth description of the experiences of authors in searching for and gaining access to unpublished data for their systematic reviews, and to give guidance on best practices for identifying, obtaining and using unpublished data. Methods This is a qualitative study analyzing in-depth interviews with authors of systematic reviews who have published Cochrane reviews or published systematic reviews outside of The Cochrane Library. We included participants who 1) were the first or senior author of a published systematic review of a drug intervention, 2) had expertise in conducting systematic reviews, searching for data, and assessing methodological biases, and 3) were able to participate in an interview in English. We used non-random sampling techniques to identify potential participants. Eighteen Cochrane authors were contacted and 16 agreed to be interviewed (89% response rate). Twenty-four non-Cochrane authors were contacted and 16 were interviewed (67% response rate). Results Respondents had different understandings of what was meant by unpublished data, including specific outcomes and methodological details. Contacting study authors was the most common method used to obtain unpublished data and the value of regulatory agencies as a data source was underappreciated. Using the data obtained was time consuming and labor intensive. Respondents described the collaboration with other colleagues and/or students required to organize, manage and use the data in their reviews, generally developing and using templates, spreadsheets and computer programs for data extraction and analysis. Respondents had a shared belief that data should be accessible but some had concerns about sharing their own data. Respondents believed that obtaining unpublished data for reviews has important public health implications. There was widespread support for government intervention to ensure open access to trial data. Conclusions Respondents uniformly agreed that the benefit of identifying unpublished data was worth the effort and was necessary to identify the true harms and benefits of drugs. Recent actions by government, such as increased availability of trial data from the European Medicines Agency, may make it easier to acquire critical drug trial data. PMID:23680054

  1. Silviculture of mixed conifer forests in eastern Oregon and Washington.

    Treesearch

    K.W. Seidel; P.H. Cochran

    1981-01-01

    The silviculture of mixed conifer forests in eastern Oregon and Washington is described. Topics discussed include ecological setting, damaging agents, silviculture, and management. The relevant literature is presented, along with unpublished research, experience, and observations. Research needs are also proposed.

  2. A Resume of Prescribed Burnings on the Piedmont National Wildlife Refuge

    Treesearch

    Eugene Czuhai; Charles T. Cushwa

    1968-01-01

    Information concerning the effects of prescribed burning on wildlife habitat in the Atlantic Piedmont is meager. Much information on this topic was in unpublished quarterly reports written by Piedmont Wildlife Refuge managers. This information has been summarized and presented chronologically.

  3. User Manual for the NASA Glenn Ice Accretion Code LEWICE: Version 2.0

    NASA Technical Reports Server (NTRS)

    Wright, William B.

    1999-01-01

    A research project is underway at NASA Glenn to produce a computer code which can accurately predict ice growth under a wide range of meteorological conditions for any aircraft surface. This report will present a description of the code inputs and outputs from version 2.0 of this code, which is called LEWICE. This version differs from previous releases due to its robustness and its ability to reproduce results accurately for different spacing and time step criteria across computing platform. It also differs in the extensive effort undertaken to compare the results against the database of ice shapes which have been generated in the NASA Glenn Icing Research Tunnel (IRT) 1. This report will only describe the features of the code related to the use of the program. The report will not describe the inner working of the code or the physical models used. This information is available in the form of several unpublished documents which will be collectively referred to as a Programmers Manual for LEWICE 2 in this report. These reports are intended as an update/replacement for all previous user manuals of LEWICE. In addition to describing the changes and improvements made for this version, information from previous manuals may be duplicated so that the user will not need to consult previous manuals to use this code.

  4. 12 CFR 510.5 - Release of unpublished OTS information.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... their official capacities. Examples of unpublished information include: (i) Information in the memory of... must be sent to the OTS at 1700 G Street NW., Washington, DC 20552, to the attention of the Corporate...

  5. Integrated Cost Accounting System.

    DTIC Science & Technology

    1992-07-27

    D., Srikant M. Datar, and Sunder Kekre . "Relevant Costs, Congestion, and Stochasticity in Production Environments." unpublished working paper...School, 1984. 113 Kekre , Sunder . "Strategic Consideration of Order Flexibility, Costs, and Delivery in Long-Term Contracts." Unpublished Working Paper

  6. Asteroid Lightcurve Analysis at the Palmer Divide Observatory: September-December 2007

    NASA Astrophysics Data System (ADS)

    Warner, Brian D.

    2008-06-01

    Lightcurves for 20 asteroids were obtained at the Palmer Divide Observatory from September-December 2007. 167 Urda; 793 Arizona; 1112 Polonia; 1325 Inanda; 1590 Tsiolkovskaja; 1741 Giclas; 2347 Vinata; 4464 Vulcano; 5720 Halweaver; 7086 Bopp; 7187 Isobe; (8309) 1996 NL1; (10496) 1986 RK; (11904) 1991 TR1; (17738) 1998 BS15; (20936) 4835 T-1; (25332) 1999 KK6; (31793) 1999 LB6; (44892) 1999 VJ8; (52314) 1991 XD. In addition, previously unpublished results from 2000 for (10936) 1998 FN11 are reported.

  7. Optical and Magnetic Resonance Investigations of 3d Ions in Single Crystal Hosts: Candidates for Tunable Solid-State Lasers

    DTIC Science & Technology

    1994-04-25

    Resonance Spectroscopy of Chromium-Doped Lanthanum Lutetium Gallium Garnet, M. H. Whitmore and D.J. Singel 8. 51V modulation of Mn5+ electron spin echoes in...Doped Lanthanum Lutetium Gallium Garnet Chapter 9 Characterization of Optical Centers in Mn.Ba3(VO4)2 178 by Spin-Echo EPR Spectroscopy I I ! I ii I i I I...previously unpublished EPR results on Cr:gehlenites (Chapter 6) and Cr:LLGG (lanthanum lutetium gallium garnet) (Chapter 8). The gehlenite spectra do

  8. 18S rRNA data indicate that Aschelminthes are polyphyletic in origin and consist of at least three distinct clades.

    PubMed

    Winnepenninckx, B; Backeljau, T; Mackey, L Y; Brooks, J M; De Wachter, R; Kumar, S; Garey, J R

    1995-11-01

    The Aschelminthes is a collection of at least eight animal phyla, historically grouped together because the absence of a true body cavity was perceived as a pseudocoelom. Analyses of 18S rRNA sequences from six Aschelminth phyla (including four previously unpublished sequences) support polyphyly for the Aschelminthes. At least three distinct groups of Aschelminthes were detected: the Priapulida among the protostomes, the Rotifera-Acanthocephala as a sister group to the protostomes, and the Nematoda as a basal group to the triploblastic Eumetazoa.

  9. Einstein: A Historical Perspective

    NASA Astrophysics Data System (ADS)

    Kormos-Buchwald, Diana

    2015-04-01

    In late 1915, Albert Einstein (1879-1955) completed as series of papers on a generalized theory of gravitation that were to constitute a major conceptual change in the history of modern physics and the crowning achievement of his scientific career. But this accomplishment came after a decade of intense intellectual struggle and was received with muted enthusiasm. Einstein's previously unpublished writings and massive correspondence, edited by the Einstein Papers Project, provide vivid insights into the historical, personal, and scientific context of the formulation, completion, and reception of GR during the first decades of the 20th century.

  10. Seizure-free outcome in randomized add-on trials of the new antiepileptic drugs.

    PubMed

    Gazzola, Deana M; Balcer, Laura J; French, Jacqueline A

    2007-07-01

    The goal of this study is to (1) provide clinically useful, previously unpublished comparative analyses of seizure-freedom rates for newer antiepileptic drugs (AEDs), and (2) recommend a standard for data presentation and analysis. Data were reviewed from placebo-controlled adjunctive trials in refractory patients of gabapentin (GPN), lamotrigine (LTG), topiramate (TOP), tiagabine (TGB), oxcarbazepine (OXC), levetiracetam (LEV), zonisamide (ZNS), and pregabalin (PGB). Seizure-freedom analyses in these publications, if included at all, consistently included both patients who completed the trial, and those who dropped out prior to completion (last observation carried forward, LOCF). This has the potential to increase reported seizure-free outcomes. Pharmaceutical companies were contacted for the provision of unpublished seizure-free data in the patients who completed the entire study. In most cases, LOCF analysis produced a higher rate of seizure freedom compared to complete analysis. A total of 0%-1.1% of the LOCF population was seizure-free in the GPN trials (complete data not available). For the remaining AEDs, seizure-freedom results in the LOCF versus complete populations were: 0.7% versus 0.8% (LTG trial); 12% versus 2.6% (OXC trial); 3.6%-6.4% versus 3.9%-7.1% (LEV trial); 3.7%-7.9% versus 1.3%-1.4% (PGB trial); and 6.0% versus 3.0% (ZNS trial, minus titration period). By employing LOCF, a clinically unrealistic picture of seizure-free rates may be reported. Access to complete data is informative, as it includes only those patients who were able to tolerate the drug at doses that produced seizure freedom. Ideally, data from both ITT and complete analyses should be made available.

  11. New Systematic Review Methodology for Visual Impairment and Blindness for the 2010 Global Burden of Disease Study

    PubMed Central

    Bourne, Rupert; Price, Holly; Taylor, Hugh; Leasher, Janet; Keeffe, Jill; Glanville, Julie; Sieving, Pamela C; Khairallah, Moncef; Wong, Tien Yin; Zheng, Yingfeng; Mathew, Anu; Katiyar, Suchitra; Mascarenhas, Maya; Stevens, Gretchen A; Resnikoff, Serge; Gichuhi, Stephen; Naidoo, Kovin; Wallace, Diane; Kymes, Steven; Peters, Colleen; Pesudovs, Konrad; Braithwaite, Tasanee; Limburg, Hans

    2014-01-01

    Purpose To describe a systematic review of population-based prevalence studies of visual impairment (VI) and blindness worldwide over the past 32 years that informs the Global Burden of Diseases, Injuries and Risk Factors Study. Methods A systematic review (Stage 1) of medical literature from 1 January 1980 to 31 January 2012 identified indexed articles containing data on incidence, prevalence and causes of blindness and VI. Only cross-sectional population-based representative studies were selected from which to extract data for a database of age- and sex-specific data of prevalence of 4 distance and one near visual loss categories (presenting and best-corrected). Unpublished data and data from studies using ‘rapid assessment’ methodology were later added (Stage 2). Results Stage 1 identified 14,908 references, of which 204 articles met the inclusion criteria. Stage 2 added unpublished data from 44 ‘rapid assessment studies’ and 4 other surveys. This resulted in a final dataset of 252 articles of 243 studies, of which 238 (98%) reported distance vision loss categories. Thirty-seven studies of the final dataset reported prevalence of mild VI and 4 reported near vision impairment. Conclusion We report a comprehensive systematic review of over 30 years of VI/blindness studies. While there has been an increase in population-based studies conducted in the 2000’s compared to previous decades; there is limited information from certain regions (eg. Central Africa and Central and Eastern Europe, and the Caribbean and Latin America), younger age groups and minimal data regarding prevalence of near vision and mild distance visual impairment. PMID:23350553

  12. Maximizing the Impact of Systematic Reviews in Health Care Decision Making: A Systematic Scoping Review of Knowledge-Translation Resources

    PubMed Central

    Chambers, Duncan; Wilson, Paul M; Thompson, Carl A; Hanbury, Andria; Farley, Katherine; Light, Kate

    2011-01-01

    Context: Barriers to the use of systematic reviews by policymakers may be overcome by resources that adapt and present the findings in formats more directly tailored to their needs. We performed a systematic scoping review to identify such knowledge-translation resources and evaluations of them. Methods: Resources were eligible for inclusion in this study if they were based exclusively or primarily on systematic reviews and were aimed at health care policymakers at the national or local level. Resources were identified by screening the websites of health technology assessment agencies and systematic review producers, supplemented by an email survey. Electronic databases and proceedings of the Cochrane Colloquium and HTA International were searched as well for published and unpublished evaluations of knowledge-translation resources. Resources were classified as summaries, overviews, or policy briefs using a previously published classification. Findings: Twenty knowledge-translation resources were identified, of which eleven were classified as summaries, six as overviews, and three as policy briefs. Resources added value to systematic reviews by, for example, evaluating their methodological quality or assessing the reliability of their conclusions or their generalizability to particular settings. The literature search found four published evaluation studies of knowledge-translation resources, and the screening of abstracts and contact with authors found three more unpublished studies. The majority of studies reported on the perceived usefulness of the service, although there were some examples of review-based resources being used to assist actual decision making. Conclusions: Systematic review producers provide a variety of resources to help policymakers, of which focused summaries are the most common. More evaluations of these resources are required to ensure users’ needs are being met, to demonstrate their impact, and to justify their funding. PMID:21418315

  13. A Rigorous Attempt to Verify Interstellar Glycine

    NASA Technical Reports Server (NTRS)

    Snyder, L. E.; Lovas, F. J.; Hollis, J. M.; Friedel, D. N.; Jewell, P. R.; Remijan, A.; Ilyushin, V. V.; Alekseev, E. A.; Dyubko, S. F.

    2004-01-01

    In 2003, Kuan, Charnley, and co-workers reported the detection of interstellar glycine (NH2CH2COOH) based on observations of 27 lines in 19 different spectral bands in one or more of the sources Sgr BP(N-LMH), Orion KL, and W51 e1/e2. They supported their detection report with rotational temperature diagrams for all three sources. In this paper, we present essential criteria which can be used in a straightforward analysis technique to confirm the identity of an interstellar asymmetric rotor such as glycine. We use new laboratory measurements of glycine as a basis for applying this analysis technique, both to our previously unpublished 12 m telescope data and to the previously published SEST data of Nummelin and colleagues. We conclude that key lines necessary for an interstellar glycine identification have not yet been found. We identify several common molecular candidates that should be examined further as more likely carriers of the lines reported as glycine. Finally, we illustrate that rotational temperature diagrams used without the support of correct spectroscopic assignments are not a reliable tool for the identification of interstellar molecules. Subject headings: ISM: abundances - ISM: clouds - ISM: individual (Sagittarius B2[N-

  14. Radiofrequency Heating Pathways for Gold Nanoparticles

    PubMed Central

    Collins, C. B.; McCoy, R. S.; Ackerson, B. J.; Collins, G. J.

    2015-01-01

    This feature article reviews the thermal dissipation of nanoscopic gold under radiofrequency (RF) irradiation. It also presents previously unpublished data addressing obscure aspects of this phenomenon. While applications in biology motivated initial investigation of RF heating of gold nanoparticles, recent controversy concerning whether thermal effects can be attributed to nanoscopic gold highlight the need to understand the involved mechanism or mechanisms of heating. Both the nature of the particle and the nature of the RF field influence heating. Aspects of nanoparticle chemistry and physics, including the hydrodynamic diameter of the particle, the oxidation state and related magnetism of the core, and the chemical nature of the ligand shell may all strongly influence to what extent a nanoparticle heats in an RF field. Aspects of RF include: power, frequency and antenna designs that emphasize relative strength of magnetic or electric fields, and also influence the extent to which a gold nanoparticle heats in RF. These nanoparticle and RF properties are analysed in the context of three heating mechanisms proposed to explain gold nanoparticle heating in an RF field. This article also makes a critical analysis of the existing literature in the context of the nanoparticle preparations, RF structure, and suggested mechanisms in previously reported experiments. PMID:24962620

  15. VizieR Online Data Catalog: NGC 3503 YSO candidates (Duronea+, 2014)

    NASA Astrophysics Data System (ADS)

    Duronea, N. U.; Vasquez, J.; Romero, G. A.; Cappa, C. E.; Barba, R.; Bronfman, L.

    2014-07-01

    The molecular observations presented in this paper were made during October 2011, with APEX at Llano de Chajnantor (Chilean Andes). In this work we use unpublished images of ATLASGAL at 870um (345GHz) (Schuller et al. 2009A&A...504..415S). (2 data files).

  16. A Review of Neurofeedback Treatment for Pediatric ADHD

    ERIC Educational Resources Information Center

    Lofthouse, Nicholas; Arnold, L. Eugene; Hersch, Sarah; Hurt, Elizabeth; DeBeus, Roger

    2012-01-01

    Objective: The aim of this paper was to review all randomized published trials and unpublished conference presentations on the neurofeedback (NF) treatment of pediatric ADHD, and their relevance, strengths, and limitations. Method: Via PsychInfo and Medline searches and contacts with NF researchers 14 studies were identified and reviewed. Results:…

  17. A Bibliography of Philippine Language Dictionaries and Vocabularies. Special Monograph Issue, Number 30.

    ERIC Educational Resources Information Center

    Hendrickson, Gail R., Comp.; Newell, Leonard E., Comp.

    This bibliography is a comprehensive listing of dictionaries and vocabularies, published and unpublished, of the Philippine languages. Introductory sections chronicle briefly the histories of Philippine lexicography and Philippine bibliographies, describe the scope of the present work, and outline the organization of the bibliography itself and…

  18. World Disarmament Kit.

    ERIC Educational Resources Information Center

    Woito, Robert, Ed.

    This kit presents a comprehensive introduction for students to arms control and disarmament issues. Included are copies of published and unpublished articles for each topic. Section I provides a self-survey to enable students to assess their own attitudes, values, and knowledge. The survey poses questions for which students select one of several…

  19. Tender love and transference: unpublished letters of C. G. Jung and Sabina Spielrein.

    PubMed

    Lothane, Z

    1999-12-01

    The author dissents from the widely accepted interpretation that the relationship between Sabina Spielrein and Carl Jung in the years 1904-1910 included sexual intercourse and constituted an ethical breach of the doctor-patient boundary in the course of a treatment. Spielrein declared that her treatment ended with her discharge from the Burghölzli hospital as Jung's patient in 1904-1905. Jung maintained he 'prolonged the relationship' in order to prevent a relapse and also referred to it as a friendship. Materials published in 1994 (letters, drafts, diaries, hospital chart) and unpublished letters recently found by the author in the Claparède archive in Geneva shed new light on previously published documents and interpretations by Carotenuto that have dominated the secondary literature since 1980. The new materials provide a more nuanced view of the Spielrein-Jung relationship and point to the function of non-erotic love in the therapeutic relationship. A new look at the Freud-Jung correspondence about the Spielrein-Jung relationship shows that Jung's perception that a sex scandal was initiated by Spielrein resulted from Jung's misreading of rumors concerning another woman; the episode had no ill effect on the relationship between Freud and Jung.

  20. Searching for unpublished data for Cochrane reviews: cross sectional study

    PubMed Central

    Bero, Lisa; Gøtzsche, Peter C

    2013-01-01

    Objective To describe the experiences of authors of Cochrane reviews in searching for, getting access to, and using unpublished data. Design Cross sectional study. Setting Cochrane reviews. Participants 2184 corresponding authors of Cochrane reviews as of May 2012. Main outcome measure Frequencies of responses to open ended and closed questions in an online survey. Results Of 5915 authors contacted by email, 2184 replied (36.9% response rate). Of those, 1656 (75.8%) had searched for unpublished data. In 913 cases (55.1% of 1656), new data were obtained and we received details about these data for 794 data sources. The most common data source was “trialists/investigators,” accounting for 73.9% (n=587) of the 794 data sources. Most of the data were used in the review (82.0%, 651/794) and in 53.4% (424/794) of cases data were provided in less than a month. Summary data were most common, provided by 50.8% (403/794) of the data sources, whereas 20.5% (163/794) provided individual patient data. In only 6.3% (50/794) of cases were data reported to have been obtained from the manufacturers, and this group waited longer and had to make more contacts to get the data. The data from manufacturers were less likely to be for individual patients and less likely to be used in the review. Data from regulatory agencies accounted for 3.0% (24/794) of the obtained data. Conclusions Most authors of Cochrane reviews who searched for unpublished data received useful information, primarily from trialists. Our response rate was low and the authors who did not respond were probably less likely to have searched for unpublished data. Manufacturers and regulatory agencies were uncommon sources of unpublished data. PMID:23613540

  1. Searching for unpublished data for Cochrane reviews: cross sectional study.

    PubMed

    Schroll, Jeppe Bennekou; Bero, Lisa; Gøtzsche, Peter C

    2013-04-23

    To describe the experiences of authors of Cochrane reviews in searching for, getting access to, and using unpublished data. Cross sectional study. Cochrane reviews. 2184 corresponding authors of Cochrane reviews as of May 2012. Frequencies of responses to open ended and closed questions in an online survey. Of 5915 authors contacted by email, 2184 replied (36.9% response rate). Of those, 1656 (75.8%) had searched for unpublished data. In 913 cases (55.1% of 1656), new data were obtained and we received details about these data for 794 data sources. The most common data source was "trialists/investigators," accounting for 73.9% (n=587) of the 794 data sources. Most of the data were used in the review (82.0%, 651/794) and in 53.4% (424/794) of cases data were provided in less than a month. Summary data were most common, provided by 50.8% (403/794) of the data sources, whereas 20.5% (163/794) provided individual patient data. In only 6.3% (50/794) of cases were data reported to have been obtained from the manufacturers, and this group waited longer and had to make more contacts to get the data. The data from manufacturers were less likely to be for individual patients and less likely to be used in the review. Data from regulatory agencies accounted for 3.0% (24/794) of the obtained data. Most authors of Cochrane reviews who searched for unpublished data received useful information, primarily from trialists. Our response rate was low and the authors who did not respond were probably less likely to have searched for unpublished data. Manufacturers and regulatory agencies were uncommon sources of unpublished data.

  2. Online Sources for Competitor Information.

    ERIC Educational Resources Information Center

    Weiss, Arthur

    Competitor information gathering is a key aspect of business planning. Information can be collected from either published or unpublished sources. Unpublished information will often be verified based on material from published sources. Published information is more likely to be factual and includes financial, stockmarket, press, market and…

  3. 1998 Gordon Research Conference on Gravitational Effects on Living Systems

    NASA Technical Reports Server (NTRS)

    Evans, Michael L.

    1998-01-01

    The Gordon Research Conference (GRC) on GRAVITATIONAL EFFECTS ON LIVING SYSTEMS was held at COLBY SAYWER 2 from 7/12/98 thru 7/17/98. The Conference was well-attended with 94 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students. In designing the formal speakers program, emphasis was placed on current unpublished research and discussion of the future target areas in this field. There was a conscious effort to stimulate lively discussion about the key issues in the field today. Time for formal presentations was limited in the interest of group discussions. In order that more scientists could communicate their most recent results, poster presentation time was scheduled. Attached is a copy of the formal schedule and speaker program and the poster program. In addition to these formal interactions, "free time" was scheduled to allow informal discussions. Such discussions are fostering new collaborations and joint efforts in the field. As you know, in the interest of promoting the presentation of unpublished and frontier-breaking research, Gordon Research Conferences does not permit publication of meeting proceedings.

  4. User Manual for the NASA Glenn Ice Accretion Code LEWICE. Version 2.2.2

    NASA Technical Reports Server (NTRS)

    Wright, William B.

    2002-01-01

    A research project is underway at NASA Glenn to produce a computer code which can accurately predict ice growth under a wide range of meteorological conditions for any aircraft surface. This report will present a description of the code inputs and outputs from version 2.2.2 of this code, which is called LEWICE. This version differs from release 2.0 due to the addition of advanced thermal analysis capabilities for de-icing and anti-icing applications using electrothermal heaters or bleed air applications. An extensive effort was also undertaken to compare the results against the database of electrothermal results which have been generated in the NASA Glenn Icing Research Tunnel (IRT) as was performed for the validation effort for version 2.0. This report will primarily describe the features of the software related to the use of the program. Appendix A of this report has been included to list some of the inner workings of the software or the physical models used. This information is also available in the form of several unpublished documents internal to NASA. This report is intended as a replacement for all previous user manuals of LEWICE. In addition to describing the changes and improvements made for this version, information from previous manuals may be duplicated so that the user will not need to consult previous manuals to use this code.

  5. 78 FR 6045 - Information Sharing Among Federal Home Loan Banks

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Banks-- specifically, the Atlanta, Chicago, Dallas, Des Moines, Indianapolis, New York, Pittsburgh, San... because part 911 of the Finance Board's regulations, which continues to govern the control of unpublished... replace part 911 with new regulations governing the control of unpublished information (which is referred...

  6. State-of-the-evidence reviews: advantages and challenges of including grey literature.

    PubMed

    Benzies, Karen M; Premji, Shahirose; Hayden, K Alix; Serrett, Karen

    2006-01-01

    Increasingly, health policy decision-makers and professionals are turning to research-based evidence to support decisions about policy and practice. Systematic reviews are useful for gathering, summarizing, and synthesizing published and unpublished research about clearly defined interventions. State-of-the-evidence reviews are broader than traditional systematic reviews and may include not only published and unpublished research, but also published and unpublished non-research literature. Decisions about whether to include this "grey literature" in a review are challenging and lead to many questions about whether the advantages outweigh the challenges. The primary purpose of this article is to describe what constitutes grey literature, and methods to locate it and assess its quality. The secondary purpose is to discuss the core issues to consider when making decisions to include grey literature in a state-of-the-evidence review. A recent state-of-the-evidence review is used as an exemplar to present advantages and challenges related to including grey literature in a review. Despite the challenges, in the exemplar, inclusion of grey literature was useful to validate the results of a research-based literature search. Decisions about whether to include grey literature in a state-of-the-evidence review are complex. A checklist to assist in decision-making was created as a tool to assist the researcher in determining whether it is advantageous to include grey literature in a review.

  7. Literatura Chicana. A Comprehensive Bibliography (1980-June, 1984). Working Bibliography Series No. 1.

    ERIC Educational Resources Information Center

    Trujillo, Roberto G.; And Others

    The 197-item bibliography on Chicano literature published from 1980 through June 1984 is presented in 10 sections: poetry (77 entries), novel (25 entries), short fiction (13 entries), theatre (7 entries), literary criticism (16 entries), anthology (24 entries), unpublished dissertations (13 entries), bibliographies and encyclopedia (6 entries),…

  8. The Current Situation in Latin American Education. Bulletin, 1963, No. 21. OE-14060

    ERIC Educational Resources Information Center

    Hauch, Charles C.

    1962-01-01

    The brief description of education in Latin American presented here is based on information available to the Office of Education, much of it in unpublished form, and provides an overview of the general situation of education in Latin America. Document contents include: (1) Introduction: Some Background Factors--historical,…

  9. Visualizing Changes in Pretest and Post-Test Student Responses with Consistency Plots

    ERIC Educational Resources Information Center

    Wittmann, Michael C.; Black, Katrina E.

    2014-01-01

    Tabular presentations of student data often hide information about the switches in responses by individual students over the course of a semester. We extend unpublished work by Kanim on "escalator diagrams," which show changes in student responses from correct to incorrect (and vice versa) while representing pre- and postinstruction…

  10. Use of the Chemical Literature as a Template to Probe Stereoselective Reactions by NMR

    ERIC Educational Resources Information Center

    Clausen, Thomas P.; Green, Thomas K.; Steiner, Benjamin

    2008-01-01

    In teaching organic chemistry laboratory at this university, we eliminated the use of "canned" experiments from textbooks. Instead, we present students with literature studies that form the basis of developing new unpublished experiments to answer specific questions. In this research approach, students are better exposed to the chemical…

  11. Exercise Following a Heart Attack: Some Special Considerations.

    ERIC Educational Resources Information Center

    Fardy, Paul S.

    This paper presents information on the effectiveness of exercise programs for heart attack victims. Some of the observations come from unpublished results of a two year experiment of the National Exercise and Heart Disease Project. The paper first establishes that a group exercise program with trained supervision is advantageous for people with…

  12. Integrating management strategies for the mountain pine beetle with multiple-resource management of lodgepole pine forests

    Treesearch

    Mark D. McGregor; Dennis M. Cole

    1985-01-01

    Provides guidelines for integrating practices for managing mountain pine beetle populations with silvicultural practices for enhancing multiple resource values of lodgepole pine forests. Summarizes published and unpublished technical information and recent research on the ecology of pest and host and presents visual and classification criteria for recognizing...

  13. Methods, Chapter 4

    Treesearch

    L.H. Pardo; E.A. Lilleskov; L.H. Geiser; M.J. Robin-Abbott

    2011-01-01

    We present an up-to-date review of current knowledge relating nitrogen (N) inputs to ecological effects, from published literature, reports, and some recent unpublished studies. Our goal is to summarize research on ecosystems across the United States. We include N gradient, long-term, and fertilizer studies; for fertilizer studies, we focus on those with low N...

  14. Two-thirds of methodological research remained unpublished after presentation at Cochrane Colloquia: an empirical analysis.

    PubMed

    Chapman, Sarah; Eisinga, Anne; Hopewell, Sally; Clarke, Mike

    2012-05-01

    To determine the extent to which abstracts of methodology research, initially presented at annual meetings of The Cochrane Collaboration, have been published as full reports and over what period of time. A secondary aim was to explore whether full publication varied in different methodological subject areas. The Cochrane Methodology Register (CMR) was searched for all abstracts reporting methodology research, presented at the 11 Cochrane Colloquia from 1997 to 2007. EMBASE, PubMed, and CMR were searched for full publications of the same research. We identified 908 eligible conference abstracts and found full publications for 312 (34.4%) of these, almost half of which (47.1%) had appeared by the end of the first year after the relevant Colloquium. The proportion of abstracts that had not been published by 3 years was 69.7%, falling to 66.2% at 5 years. Publication varied considerably between different methodological areas. Approximately two-thirds of methodological research studies presented at Cochrane Colloquia remain unpublished as full papers at least 5 years later. This highlights the importance of searching conference abstracts if one wishes to find as comprehensive and complete a sample of methodological research as possible. Crown Copyright © 2012. Published by Elsevier Inc. All rights reserved.

  15. New Light Curves and Analysis of the Overcontact Binaries PP Lac and DK Sge

    NASA Astrophysics Data System (ADS)

    Sanders, S. J.; Hargis, J. R.; Bradstreet, D. H.

    2004-12-01

    As a by-product of the ongoing work with the Catalog and AtLas of Eclipsing Binaries database (CALEB; Bradstreet et al. 2004), several hundred eclipsing binary systems have been identified that have either unpublished or poor quality light curves. We present new V & Rc light curves for the overcontact systems PP Lac and DK Sge, both chosen because their deep eclipses (peak-to-peak amplitudes of nearly 0.7 mag) help constrain the light curve modelling. Data were obtained using the 41-cm telescope at the Eastern University Observatory equipped with an SBIG ST-10XME CCD. PP Lac (P= 0.40116 d) is a W-type contact binary with only one previously published light curve (Dumont & Maraziti 1990), but the data are sparse and almost non-existent at primary eclipse. Modelling of these data gave varying results; the published mass ratios differ by nearly 0.3. Our data confirms the noted differing eclipse depths but we find the primary eclipse to be total. We present a new light curve solution using Binary Maker 3 (Bradstreet & Steelman 2002) and Wilson-Devinney, finding the mass ratio to be well-constrained by the duration of total eclipse. A period study will be presented using previously existing and newly derived times of minimum light. DK Sge (P=0.62182 d) appears to be an A-type contact binary with no published light curve. The eclipses are partial, with the primary eclipse being deeper by about 0.08 mag. The maxima show evidence of a slight asymmetry, although the light curve appears to be repeatable over the 1 month of observations. We present the first light curve solution using Binary Maker 3 and Wilson-Devinney, but have limited mass ratio constraints due to the absence of radial velocity data. A period study will be presented using previously existing and newly derived times of minimum light.

  16. Human myiasis in New Zealand: imported and indigenously-acquired cases: the species of concern and clinical aspects.

    PubMed

    Derraik, Jose G B; Heath, Allen C G; Rademaker, Marius

    2010-09-10

    Reports of myiasis in humans in New Zealand are somewhat rare, and little attention has been paid to this issue in the local medical literature. A number of Diptera (fly) families present in New Zealand have been associated with cases of human myiasis: Calliphoridae (7 species), Fanniidae (2 species), Muscidae (3 species), Oestridae (4 species), Phoridae (3 species), Psychodidae (1 species), Sarcophagidae (2 species), Stratiomyidae (1 species) and Syrphidae (1 species). Despite these numbers, there have only been 6 published records and we obtained further 16 unpublished reports of myiasis acquired in New Zealand. Records of imported myiasis in humans are also rare, with only 2 published and 6 unpublished cases obtained. As many medical practitioners are unaware of myiasis or encounter it rarely, we provide a brief discussion of the clinical features and treatment.

  17. 12 CFR 911.3 - Prohibition on unauthorized use and disclosure of unpublished information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... contract to provide services to the supervised entity or Bank member. (e) Government agencies. The Finance... control by any person, supervised entity, Bank member, government agency, or other entity of unpublished... as authorized in writing by the Finance Board, no person, supervised entity, Bank member, government...

  18. Silviculture of southwestern mixed conifers and aspen: the status of our knowledge

    Treesearch

    John R. Jones

    1974-01-01

    Describes the status of our knowledge about mixed conifer silviculture in the interior Southwest. Ecological background is reviewed first, followed by description of silvicultural methods. Relevant literature is discussed, along with observations, experience, and results of unpublished research. Contains unpublished input by subject-matter specialists and southwestern...

  19. 37 CFR 201.23 - Transfer of unpublished copyright deposits to the Library of Congress.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... copyright deposits to the Library of Congress. 201.23 Section 201.23 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES GENERAL PROVISIONS § 201.23 Transfer of unpublished copyright deposits to the Library of Congress. (a) General. This section prescribes...

  20. 37 CFR 201.23 - Transfer of unpublished copyright deposits to the Library of Congress.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... copyright deposits to the Library of Congress. 201.23 Section 201.23 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES GENERAL PROVISIONS § 201.23 Transfer of unpublished copyright deposits to the Library of Congress. (a) General. This section prescribes...

  1. 37 CFR 201.23 - Transfer of unpublished copyright deposits to the Library of Congress.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... copyright deposits to the Library of Congress. 201.23 Section 201.23 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES GENERAL PROVISIONS § 201.23 Transfer of unpublished copyright deposits to the Library of Congress. (a) General. This section prescribes...

  2. 37 CFR 201.23 - Transfer of unpublished copyright deposits to the Library of Congress.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... copyright deposits to the Library of Congress. 201.23 Section 201.23 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES GENERAL PROVISIONS § 201.23 Transfer of unpublished copyright deposits to the Library of Congress. (a) General. This section prescribes...

  3. Plasma Dynamics of the Arc-Driven Rail Gun

    DTIC Science & Technology

    1980-09-01

    Authors’ unpublished calculations. 11. A.B. Cambel , Plasma Physics and Magnetofluidmechanics (McGraw-Hill New York, 1963), Chap. 8. ’ 16 k T P = (1 +cO...Energy, and Forces (Wiley, New York, 1960), Chap. 9. 10. Authors’ unpublished calculations. 11. A.B. Cambel , Plasma Physics and Magnetofluidmechanics

  4. 77 FR 71561 - Health and Safety Data Reporting; Addition of Certain Chemicals

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-03

    ... be, incorporated into consumer products to report certain unpublished health and safety studies to... the submission of TSCA section 8(d) health and safety studies from processors and distributors of... be, incorporated into consumer products to report certain unpublished health and safety studies to...

  5. Morphology of the limbs in the semi-fossorial desert rodent species of Tympanoctomys (Octodontidae, Rodentia)

    PubMed Central

    Perez, M. Julieta; Barquez, Ruben M.; Diaz, M. Monica

    2017-01-01

    Abstract Here, a detailed description of the forelimbs and hindlimbs of all living species of the genus Tympanoctomys are presented. These rodents, highly adapted to desert environments, are semi-fossorial with capacity to move on the surface as well as to build burrows. The shape, structure, and size of the limbs are described. Contrary to what was expected for scratch digging semi-fossorial species, Tympanoctomys have slender humerus, radius and ulna; with narrow epicondyles of the humerus and short olecranon of the ulna with poorly developed processes. Following our descriptions, no intrageneric morphological variation regarding to the configuration of the limbs was detected, probably due to phylogenetic proximity, and not related to specific variations in response to different use of substrates or habits. The obtained results constitute a source of previously unpublished information as well as an important base for future analysis in different studies, such as morphometric, morpho-functional, or phylogenetic researches. PMID:29118644

  6. A Comparative Taphonomic Analysis of 24 Trophy Skulls from Modern Forensic Cases.

    PubMed

    Yucha, Josephine M; Pokines, James T; Bartelink, Eric J

    2017-09-01

    Cranial remains retained from fallen enemies are commonly referred to as "trophy skulls," and many such crania were acquired as souvenirs by U.S. servicemembers during WWII and the Vietnam conflict. These remains increasingly have become the subject of forensic anthropological analysis as their possessors, typically veterans or their relatives, try to discard or repatriate them. The present research uses a qualitative analytical approach to review 24 cases of reported trophy skulls (14 previously unpublished cases and 10 from the literature) to determine which perimortem and postmortem characteristics are most useful for generating a taphonomic profile. Overall, the taphonomic signature of trophy remains includes traits relating to acquisition and preparation, ornamental display, and subsequent curation. Contextual evidence and the biological profile also are considered when determining the possible origin of human cranial remains as a trophy skull. Thorough taphonomic analysis will aid in identifying these types of remains as trophy skulls. © 2017 American Academy of Forensic Sciences.

  7. Overcoming a nucleosomal barrier to replication

    PubMed Central

    Chang, Han-Wen; Pandey, Manjula; Kulaeva, Olga I.; Patel, Smita S.; Studitsky, Vasily M.

    2016-01-01

    Efficient overcoming and accurate maintenance of chromatin structure and associated histone marks during DNA replication are essential for normal functioning of the daughter cells. However, the molecular mechanisms of replication through chromatin are unknown. We have studied traversal of uniquely positioned mononucleosomes by T7 replisome in vitro. Nucleosomes present a strong, sequence-dependent barrier for replication, with particularly strong pausing of DNA polymerase at the +(31–40) and +(41–65) regions of the nucleosomal DNA. The exonuclease activity of T7 DNA polymerase increases the overall rate of progression of the replisome through a nucleosome, likely by resolving nonproductive complexes. The presence of nucleosome-free DNA upstream of the replication fork facilitates the progression of DNA polymerase through the nucleosome. After replication, at least 50% of the nucleosomes assume an alternative conformation, maintaining their original positions on the DNA. Our data suggest a previously unpublished mechanism for nucleosome maintenance during replication, likely involving transient formation of an intranucleosomal DNA loop. PMID:27847876

  8. The flood control controversy: Big dams, little dams, and land management

    USGS Publications Warehouse

    Leopold, Luna Bergere; Maddock, Thomas

    1954-01-01

    The purpose of this book is to investigate the facts regarding flood control, a subject that has given rise to extreme controversy in the United States in recent years. The question of flood control is obviously a vital one not only to the United States but to many other countries. It is hoped that this book may lead to a far clearer understanding of the facts involved and so may prove a truly important influence in reconciling existing differences of opinion.Most of the material presented here has not previously been available to the general reader nor has it been easily accessible to professional people. Much of it, in fact, has been gathered by the authors from unpublished reports of government agencies and from discussions with technicians in the field. Part of the material, on the other hand, such as the sections on flood plain formation and the hydrologic effect of small dams, stems from original research by the authors.

  9. Comparison of the NIST and PTB Air-Kerma Standards for Low-Energy X-Rays.

    PubMed

    O'Brien, Michelle; Bueermann, Ludwig

    2009-01-01

    A comparison has been made of the air-kerma standards for low-energy x rays at the National Institute of Standards and Technology (NIST) and the Physikalisch-Technische Bundesanstalt (PTB). The comparison involved a series of measurements at the PTB and the NIST using the air-kerma standards and two NIST reference-class transfer ionization chamber standards. Results are presented for the reference radiation beam qualities in the range from 25 kV to 50 kV for low energy x rays, including the techniques used for mammography dose traceability. The tungsten generated reference radiation qualities, between 25 kV and 50 kV used for this comparison, are new to NIST; therefore this comparison will serve as the preliminary comparison for NIST and a verification of the primary standard correction factors. The mammography comparison will repeat two previously unpublished comparisons between PTB and NIST. The results show the standards to be in reasonable agreement within the standard uncertainty of the comparison of about 0.4 %.

  10. Einstein's steady-state theory: an abandoned model of the cosmos

    NASA Astrophysics Data System (ADS)

    O'Raifeartaigh, Cormac; McCann, Brendan; Nahm, Werner; Mitton, Simon

    2014-09-01

    We present a translation and analysis of an unpublished manuscript by Albert Einstein in which he attempted to construct a `steady-state' model of the universe. The manuscript, which appears to have been written in early 1931, demonstrates that Einstein once explored a cosmic model in which the mean density of matter in an expanding universe is maintained constant by the continuous formation of matter from empty space. This model is very different to previously known Einsteinian models of the cosmos (both static and dynamic) but anticipates the later steady-state cosmology of Hoyle, Bondi and Gold in some ways. We find that Einstein's steady-state model contains a fundamental flaw and suggest that it was abandoned for this reason. We also suggest that he declined to explore a more sophisticated version because he found such theories rather contrived. The manuscript is of historical interest because it reveals that Einstein debated between steady-state and evolving models of the cosmos decades before a similar debate took place in the cosmological community.

  11. Geologic map of the Grand Canyon 30' x 60' quadrangle, Coconino and Mohave Counties, northwestern Arizona

    USGS Publications Warehouse

    Billingsley, G.H.

    2000-01-01

    This digital map database, compiled from previously published and unpublished data as well as new mapping by the author, represents the general distribution of bedrock and surficial deposits in the map area. Together with the accompanying pamphlet, it provides current information on the geologic structure and stratigraphy of the Grand Canyon area. The database delineates map units that are identified by general age and lithology following the stratigraphic nomenclature of the U.S. Geological Survey. The scale of the source maps limits the spatial resolution (scale) of the database to 1:100,000 or smaller.

  12. Bloody otorrhea after robotically assisted laparoscopic prostatectomy.

    PubMed

    Cohen, Andrew; Ledezma-Rojas, Rodrigo; Mhoon, Ernest; Zagaja, Gregory

    2015-06-01

    Bilateral bloody otorrhea is a rare complication of surgery and to our knowledge a previously unpublished event. We review the case of a 50-year-old male who underwent robotic-assisted laparoscopic radical prostatectomy (RALP) with bilateral lymphadenectomy for Gleason's Score 4 + 4 = 8 prostate cancer. Bloody discharge from bilateral auditory canals was noted upon removal of the surgical drapes. Otolaryngologic examination revealed bilateral anterior auditory canal hematomas without any loss of hearing. Steep Trendelenburg position in combination with perioperative anticoagulants may have contributed to this complication. Given the rarity of this event no specific risk factors are identified.

  13. Songlines and navigation in Wardaman and other Australian Aboriginal cultures

    NASA Astrophysics Data System (ADS)

    Norris, Ray P.; Harney, Bill Yidumdum

    2014-07-01

    We discuss the songlines and navigation of the Wardaman people, and place them in context by comparing them with corresponding practices in other Aboriginal Australian language groups, using previously-unpublished information and also information drawn from the literature. Songlines are effectively oral maps of the landscape, enabling the transmission of oral navigational skills in cultures that do not have a written language. In many cases, songlines on the Earth are mirrored by songlines in the sky, enabling the sky to be used as a navigational tool, both by using it as a compass and by using it as a mnemonic.

  14. Nuclear Data Sheets for A = 92

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baglin, Coral M.

    2012-10-15

    Nuclear structure and decay data pertaining to all nuclides with mass number A = 92 (As, Se, Br, Kr, Rb, Sr, Y, Zr, Nb, Mo, Tc, Ru, Rh, Pd) have been compiled and evaluated, and incorporated into the ENSDF data file. All literature available by 15 September 2012 has been considered. This evaluation supersedes the previous publication for this mass chain (Coral M. Baglin, Nuclear Data Sheets 91, 423 (2000) (November 2000 cutoff date)), and subsequent unpublished reevaluations by C.M. Baglin for {sup 92}Kr (January 2004 literature cut-off) and {sup 92}Sr (August 2003 literature cut-off).

  15. Smithsonian Astrophysical Observatory (SAO) star catalog (Sao staff 1966, edition ADC 1989): Documentation for the machine-readable version

    NASA Technical Reports Server (NTRS)

    Roman, Nancy G.; Warren, Wayne H., Jr.

    1989-01-01

    An updated, corrected, and extended machine readable version of the catalog is described. Published and unpublished errors discovered in the previous version were corrected, and multiple star and supplemental BD identifications were added to stars where more than one SAO entry has the same Durchmusterung number. Henry Draper Extension (HDE) numbers were added for stars found in both volumes of the extension. Data for duplicate SAO entries (those referring to the same star) were flagged. J2000 positions in usual units and in radians were added.

  16. 37 CFR 201.23 - Transfer of unpublished copyright deposits to the Library of Congress.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... copyright deposits to the Library of Congress. 201.23 Section 201.23 Patents, Trademarks, and Copyrights U.S. COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT OFFICE AND PROCEDURES GENERAL PROVISIONS § 201.23 Transfer of unpublished copyright deposits to the Library of Congress. (a) General. This section prescribes...

  17. Buoy Technology survey USCG Buoy Development Review

    DTIC Science & Technology

    1990-10-01

    by the United States Coadst Guard, IALA Conference, No. 3.1.5, Tokyo, 1980 . 3P.H. Glage, Design, Procurement and Testing of Plastic Fast Water Buoys on...may include published reports, unpublished reports, and USCG files. 23 PROJECT SUMMARY NO. 1 ARTICULATED BEACON DEVELOPMENT DATES: 1980 to Present...PROJECT DATE’%: 1980 to Present OBJECTIVE: The purpose of this project is to design a special buoy for use in exposed offshore locations where high

  18. Preferred Teaching Styles and Modes of Thinking among University Students in Mainland China

    ERIC Educational Resources Information Center

    Zhang, Li-fang

    2006-01-01

    The present study had three purposes. The first was to further explore the psychometric properties of the Preferred Thinking Styles in Teaching Inventory [Zhang, L. F. (2003). "The preferred thinking styles in teaching inventory." Unpublished test. The University of Hong Kong: Hong Kong]. The second was to test the hypothesis that the…

  19. Prevalence and serotypes of intimin (eae) positive Shiga toxin-producing E. coli colonizing cattle arriving at fed beef and cull cow plants in the US

    USDA-ARS?s Scientific Manuscript database

    Category: pre/post harvest pathogens Published: unpublished to date Objective: The objective of this study was to determine whether inherent differences in fed cattle and cull cattle sources affect the prevalence and serogroups present of intimin positive STEC, and identify unappreciated serogro...

  20. FORTY YEARS OF SCHOOL PLANT DISSERTATIONS. A REVIEW WITH SUGGESTIONS FOR FUTURE RESEARCH.

    ERIC Educational Resources Information Center

    CLASEN, ROBERT E.

    A BIBLIOGRAPHIC REVIEW OF PUBLISHED AND UNPUBLISHED DISSERTATIONS RELATED TO SCHOOL PLANTS IS COMPILED BY YEARS BEGINNING WITH STUDIES PRODUCED IN 1921 AND IS CROSS INDEXED BY TOPIC. IT REVIEWS THE SCHOOL PLANT PROBLEMS MOST INVESTIGATED BY STUDENTS. A BRIEF HISTORY OF SCHOOL BUILDING DEVELOPMENT IS PRESENTED IN LIGHT OF CORRESPONDING ECONOMIC AND…

  1. Ecology, pathology, and management of Port-Orford-Cedar (Chamaecyparis lawsoniana).

    Treesearch

    Donald B. Zobel; Lewis F. Roth; Glenn M. Hawk

    1982-01-01

    Information about the biology, diseases, and management of Port-Orford- cedar was collected from the literature, from unpublished research data of the authors and the USDA Forest Service, conversations with personnel involved in all facets of Port-Orford-cedar management, and visits to stands throughout the range of the species. Information is summarized and presented...

  2. RESEARCH IN READING FOR THE MIDDLE GRADES. AN ANNOTATED BIBLIOGRAPHY.

    ERIC Educational Resources Information Center

    CUTTS, WARREN G.

    THIS BULLETIN PRESENTS RESEARCH STUDIES IN READING ON THE UPPER ELEMENTARY GRADE LEVEL DURING THE PERIOD FROM 1955 THROUGH 1960. THIS COMPILATION WAS UNDERTAKEN BY THE OFFICE OF EDUCATION IN AN ATTEMPT TO BRING TOGETHER THE UNPUBLISHED AS WELL AS PUBLISHED STUDIES OF THAT 5-YEAR PERIOD. THE 238 STUDIES WHICH ARE OUTLINED, SUMMARIZED, AND ANNOTATED…

  3. [The dinner of interns of the Hospital of Paris, 1855].

    PubMed

    Gourevitch, Danielle

    2015-01-01

    Based on a hitherto unpublished notebook this paper describes and analyses the "banquet de l'internat" en 1855, the social dinner shared by the "internes" or residents, former and present, and their masters, in a famous Parisian restaurant. Some thirty year later another "banquet" will be organized for the first young women who just became internes.

  4. Center for the Polyurethanes Industry summary of unpublished industrial hygiene studies related to the evaluation of emissions of spray polyurethane foam insulation.

    PubMed

    Wood, Richard D

    2017-09-01

    Spray polyurethane foam (SPF) insulation is used as thermal insulation for residential and commercial buildings. It has many advantages over other forms insulation; however, concerns have been raised related to chemical emissions during and after application. The American Chemistry Council's (ACC's) Center for the Polyurethanes Industry (CPI) has gathered previously unpublished industrial hygiene air sampling studies submitted by member companies that were completed during an eight-year period from 2007-2014. These studies address emissions from medium density closed cell and low density open cell formulations. This article summarizes the results of personal and area air samples collected during application and post application of SPF to interior building surfaces in both laboratory and field environments. Chemicals of interest included: Volatile Organic Compounds (VOCs), methylene diphenyl diisocyanate (MDI), flame retardants, amine catalysts, blowing agents, and aldehydes. Overall, the results indicate that SPF applicators and workers in close proximity to the application are potentially exposed to MDI in excess of recommended and governmental occupational exposure limits and should use personal protective equipment (PPE) consisting of air supplied respirators and full-body protective clothing to reduce exposure. Catalyst emissions can be reduced by using reactive catalysts in SPF formulations, and mechanical ventilation is important in controlling emissions during and after application.

  5. Ozone and temperature trends

    NASA Technical Reports Server (NTRS)

    Stolarski, Richard S.; Fioletov, Vitali; Bishop, Lane; Godin, Sophie; Bojkov, Rumen D.; Kirchhoff, Volker; Chanin, Marie-Lise; Zawodny, Joseph M.; Zerefos, Christos S.; Chu, William

    1991-01-01

    An update of the extensive reviews of the state of knowledge of measured ozone trends published in the Report of the International Ozone Trends Panel is presented. The update contains a review of progress since these reports, including reviewing of the ozone records, in most cases through March 1991. Also included are some new, unpublished reanalyses of these records including a complete reevaluation of 29 stations located in the former Soviet Union. The major new advance in knowledge of the measured ozone trend is the existence of independently calibrated satellite data records from the Total Ozone Mapping Spectrometer (TOMS) and Stratospheric Aerosol and Gas Experiment (SAG) instruments. These confirm many of the findings, originally derived from the Dobson record, concerning northern mid-latitude changes in ozone. We now have results from several instruments, whereas the previously reported changes were dependent on the calibration of a single instrument. This update will compare the ozone records from many different instruments to determine whether or not they provide a consistent picture of the ozone change that has occurred in the atmosphere. The update also briefly considers the problem of stratospheric temperature change. As in previous reports, this problem received significantly less attention, and the report is not nearly as complete. This area needs more attention in the future.

  6. The Swift/BAT Hard X-ray Transient Monitor

    NASA Technical Reports Server (NTRS)

    Krimm, H. A.; Holland, S. T.; Corbet, R.H.D.; Pearlman, A. B.; Romano, P.; Kennea, J. A.; Bloom, J. S.; Barthelmy, S. D.; Baumgartner, W. H.; Cummings, J. R.; hide

    2013-01-01

    The Swift/Burst Alert Telescope (BAT) hard X-ray transient monitor provides near real-time coverage of the X-ray sky in the energy range 15-50 keV. The BAT observes 88% of the sky each day with a detection sensitivity of 5.3 mCrab for a full-day observation and a time resolution as ne as 64 seconds. The three main purposes of the monitor are (1) the discovery of new transient X-ray sources, (2) the detection of outbursts or other changes in the ux of known X-ray sources, and (3) the generation of light curves of more than 900 sources spanning over eight years. The primary interface for the BAT transient monitor is a public web page. Since 2005 February, 242 sources have been detected in the monitor, 149 of them persistent and 93 detected only in outburst. Among these sources, 16 were previously unknown and discovered in the transient monitor. In this paper, we discuss the methodology and the data processing and ltering for the BAT transient monitor and review its sensitivity and exposure. We provide a summary of the source detections and classify them according to the variability of their light curves. Finally, we review all new BAT monitor discoveries and present basic data analysis and interpretations for those sources with previously unpublished results.

  7. Direct Detection and Orbit Analysis of the Exoplanets HR 8799 bcd from Archival 2005 Keck/NIRC2 Data

    NASA Technical Reports Server (NTRS)

    Currie, Thayne; Fukagawa, Misato; Thalmann, Christian; Matsumura, Soko; Plavchan, Peter

    2012-01-01

    We present previously unpublished July 2005 H-band coronagraphic data of the young, planet-hosting star HR 8799 from the newly-released Keck/NIRC2 archive. Despite poor observing conditions, we detect three of the planets (HR 8799 bcd), two of them (HR 8799 bc) without advanced image processing. Comparing these data with previously published 1998-2011 astrometry and that from re-reduced October 2010 Keck data constrains the orbits of the planets. Analyzing the planets' astrometry separately, HR 8799 d's orbit is likely inclined at least 25 deg from face-on and the others may be on in inclined orbits. For semimajor axis ratios consistent with a 4:2:1 mean-motion resonance our analysis yields precise values for HR 8799 bcd's orbital parameters and strictly constrains the planets' eccentricities to be less than 0.18-0.3. However, we find no acceptable orbital solutions with this resonance that place the planets in face-on orbits; HR 8799 d shows the largest deviation from such orbits. Moreover, few orbits make HR 8799 d coplanar with b and c, whereas dynamical stability analyses used to constrain the planets' masses typically assume coplanar and/or fare.on orbits. This paper illustrates the significant science gain enabled with the release of the NIRC2 archive.

  8. The Nature and Effects of Transformational School Leadership: A Meta-Analytic Review of Unpublished Research

    ERIC Educational Resources Information Center

    Leithwood, Kenneth; Sun, Jingping

    2012-01-01

    Background: Using meta-analytic review techniques, this study synthesized the results of 79 unpublished studies about the nature of transformational school leadership (TSL) and its impact on the school organization, teachers, and students. This corpus of research associates TSL with 11 specific leadership practices. These practices, as a whole,…

  9. Short-term international migration trends in England and Wales from 2004 to 2009.

    PubMed

    Whitworth, Simon; Loukas, Konstantinos; McGregor, Ian

    2011-01-01

    Short-term migration estimates for England and Wales are the latest addition to the Office for National Statistics (ONS) migration statistics. This article discusses definitions of short-term migration and the methodology that is used to produce the estimates. Some of the estimates and the changes in the estimates over time are then discussed. The article includes previously unpublished short-term migration statistics and therefore helps to give a more complete picture of the size and characteristics of short-term international migration for England and Wales than has previously been possible. ONS have identified a clear user requirement for short-term migration estimates at local authority (LA) level. Consequently, attention is also paid to the progress that has been made and future work that is planned to distribute England and Wales short-term migration estimates to LA level.

  10. Agricultural, domestic and handicraft folk uses of plants in the Tyrrhenian sector of Basilicata (Italy)

    PubMed Central

    Salerno, Giovanni; Guarrera, Paolo Maria; Caneva, Giulia

    2005-01-01

    Background Research was carried out into agricultural and domestic-handicraft uses in folk traditions in the Tyrrhenian sector of the Basilicata region (southern Italy), as it is typically representative of ethnobotanical applications in the Mediterranean area. From the point of view of furnishing a botanical support for the study of local "material culture" data was collected through field interviews of 49 informants, most of whom were farmers. Results The taxa cited are 60, belonging to 32 botanical families, of which 18 are employed for agricultural uses and 51 for domestic-handicraft folk uses. Data show a diffuse use of plants for many purposes, both in agricultural (present uses 14%; past uses 1%) and for domestic-handicraft use (present uses 40%; past uses 45%); most of the latter are now in decline. Conclusion 60 data look uncommon or typical of the places studied. Some domestic-handicraft folk uses are typical of southern Italy (e.g. the use of Ampelodesmos mauritanicus for making ties, ropes, torches, baskets or that of Acer neapolitanum for several uses). Other uses (e.g. that of Inula viscosa and Calamintha nepeta for peculiar brooms, and of Origanum heracleoticum for dyeing wool red) are previously unpublished. PMID:16270919

  11. Third European Stroke Science Workshop.

    PubMed

    Dichgans, Martin; Planas, Anna M; Biessels, Geert Jan; van der Worp, Bart; Sudlow, Cathie; Norrving, Bo; Lees, Kennedy; Mattle, Heinrich P

    2016-07-01

    Lake Eibsee, Garmisch-Partenkirchen, November 19 to 21, 2015: The European Stroke Organization convened >120 stroke experts from 27 countries to discuss latest results and hot topics in clinical, translational, and basic stroke research. Since its inception in 2011, the European Stroke Science Workshop has become a cornerstone of European Stroke Organization's academic activities and major highlight for researchers in the field. Participants include stroke researchers at all career stages who convene for plenary lectures and discussions, thus facilitating crosstalk among researchers from different fields. As in previous years, the workshop was organized into 7 scientific sessions each focusing on a major research topic. All sessions started with a keynote lecture that provided an overview on current developments and set the scene for the following presentations. The latter were short focused talks on a timely topic and included the most recent findings, including unpublished data. A new element at this year's meeting was a hot topic session in which speakers had to present a provocative concept or update sharply within 5 minutes. In the following, we summarize the key contents of the meeting. The program is provided in the online-only Data Supplement. © 2016 American Heart Association, Inc.

  12. A revised annotated checklist of the Chironomidae (Insecta: Diptera) of the southeastern United States

    USGS Publications Warehouse

    Caldwell, Broughton A.; Hudson, Patrick L.; Lenat, David R.; Smith, David

    1997-01-01

    A revised annotated checklist for the chironomid midges (Diptera: Chironomidae) of the southeastern United States is presented that includes the states of Alabama, Florida, Georgia, North Carolina, South Carolina, and Tennessee. Much of the information concerns occurrence and habitat preference records based upon the authors' data, as well as published and unpublished data. Some information is also presented that includes aspects of biology, habitat preference, bibliographic sources, and nomenclatorial changes. Based upon the present work, the chironomid fauna of the southeastern states is comprised of 189 genera (172 described, 17 informally or unofficially described) and 754 species (505 described, 17 informally or unofficially described, 33 that are assumed for generic or subgeneric presence only, 197 estimated species, and 2 species groups). Several new species synonyms and generic placements are recognized. Thirty-eight genera known from the Nearctic region remain unknown from the southeastern states. Diversity of species was greatest in the subfamily Chironominae, considering named as well as unnamed and estimated species. There were no significant changes in overall regional distribution patterns of subfamilies or habitat preferences form that which has been previously reported. The greatest totals for regional records, habitat types, and state occurrences were the Coastal Plain (378), streams (271), and North Carolina (373), respectively.

  13. The Impact of Head Start on Children, Families and Communities. Final Report of the Head Start Evaluation, Synthesis and Utilization Project.

    ERIC Educational Resources Information Center

    McKey, Ruth Hubbell; And Others

    Including all Head Start research (both published and unpublished) and using, when possible, the statistical technique of meta-analysis, this final report of the Head Start Evaluation, Synthesis, and Utilization Project presents findings on the impact of Head Start on children's cognitive and socioemotional development, on child health and health…

  14. User's Manual for LEWICE Version 3.2

    NASA Technical Reports Server (NTRS)

    Wright, William

    2008-01-01

    A research project is underway at NASA Glenn to produce a computer code which can accurately predict ice growth under a wide range of meteorological conditions for any aircraft surface. This report will present a description of the code inputs and outputs from version 3.2 of this software, which is called LEWICE. This version differs from release 2.0 due to the addition of advanced thermal analysis capabilities for de-icing and anti-icing applications using electrothermal heaters or bleed air applications, the addition of automated Navier-Stokes analysis, an empirical model for supercooled large droplets (SLD) and a pneumatic boot option. An extensive effort was also undertaken to compare the results against the database of electrothermal results which have been generated in the NASA Glenn Icing Research Tunnel (IRT) as was performed for the validation effort for version 2.0. This report will primarily describe the features of the software related to the use of the program. Appendix A has been included to list some of the inner workings of the software or the physical models used. This information is also available in the form of several unpublished documents internal to NASA. This report is intended as a replacement for all previous user manuals of LEWICE. In addition to describing the changes and improvements made for this version, information from previous manuals may be duplicated so that the user will not need to consult previous manuals to use this software.

  15. Enzymatic cybernetics: an unpublished work by Jacques Monod.

    PubMed

    Gayon, Jean

    2015-06-01

    In 1959, Jacques Monod wrote a manuscript entitled Cybernétique enzymatique [Enzymatic cybernetics]. Never published, this unpublished manuscript presents a synthesis of how Monod interpreted enzymatic adaptation just before the publication of the famous papers of the 1960s on the operon. In addition, Monod offers an example of a philosophy of biology immersed in scientific investigation. Monod's philosophical thoughts are classified into two categories, methodological and ontological. On the methodological side, Monod explicitly hints at his preferences regarding the scientific method in general: hypothetical-deductive method, and use of theoretical models. He also makes heuristic proposals regarding molecular biology: the need to analyse the phenomena in question at the level of individual cells, and the dual aspect of all biological explanation, functional and evolutionary. Ontological issues deal with the notions of information and genetic determinism, "cellular memory", the irrelevance of the notion of "living matter", and the usefulness of a cybernetic comprehension of molecular biology. Copyright © 2015 Académie des sciences. Published by Elsevier SAS. All rights reserved.

  16. Geologic map and map database of the Palo Alto 30' x 60' quadrangle, California

    USGS Publications Warehouse

    Brabb, E.E.; Jones, D.L.; Graymer, R.W.

    2000-01-01

    This digital map database, compiled from previously published and unpublished data, and new mapping by the authors, represents the general distribution of bedrock and surficial deposits in the mapped area. Together with the accompanying text file (pamf.ps, pamf.pdf, pamf.txt), it provides current information on the geologic structure and stratigraphy of the area covered. The database delineates map units that are identified by general age and lithology following the stratigraphic nomenclature of the U.S. Geological Survey. The scale of the source maps limits the spatial resolution (scale) of the database to 1:62,500 or smaller.

  17. Geologic map and map database of western Sonoma, northernmost Marin, and southernmost Mendocino counties, California

    USGS Publications Warehouse

    Blake, M.C.; Graymer, R.W.; Stamski, R.E.

    2002-01-01

    This digital map database, compiled from previously published and unpublished data, and new mapping by the authors, represents the general distribution of bedrock and surficial deposits in the mapped area. Together with the accompanying text file (wsomf.ps, wsomf.pdf, wsomf.txt), it provides current information on the geologic structure and stratigraphy of the area covered. The database delineates map units that are identified by general age and lithology following the stratigraphic nomenclature of the U.S. Geological Survey. The scale of the source maps limits the spatial resolution (scale) of the database to 1:62,500 or smaller.

  18. The squirrel monkey as a candidate for space flight

    NASA Technical Reports Server (NTRS)

    Brizzee, K. R.; Ordy, J. M.; Kaack, B.

    1977-01-01

    Because of its size and other unique diurnal-primate characteristics, the squirrel monkey is used in: (1) actual bioflight missions, (2) in laboratory tests designed to clarify the risks to man during launch and recovery as well as in hazardous spaceflight environments; and (3) in the acquisition of data on unknown risks encountered in long duration space exploration. Pertinent data concerning samiri sciureus as described in published and unpublished reports are summarized. Topics include: taxonomy, ethology, life history, sensory-learning-motor capabilities in primate perspective, anatomy and physiology (including homeostatic adaptation to stress), susceptibility to environmental hazards, reproduction, care and clinical management, and previous use in aerospace biomedical research.

  19. The Size Distribution of Jupiter-Family Cometary Nuclei

    NASA Technical Reports Server (NTRS)

    Weissman, Paul R.; Lowry, Stephen C.

    2003-01-01

    Introduction: We are continuing our program to determine the size distribution of cometary nuclei. We have compiled a catalog of 105 measurements of 57 cometary nuclei, drawn from the general literature, from our own program of CCD photometry of distant cometary nuclei (Lowry and Weissman), and from unpublished observations by colleagues. We model the cumulative size distribution of the nuclei as a power law. Previous determinations of the size distribution slope do not agree. Fernandez et al. found a slope of alpha = 2.65+/-0.25 whereas Lowry et al. and Weissman and Lowry each found a slope of alpha = 1.60+/-0.10.

  20. Efficacy of rational emotive therapy (RET) with children: a critical re-appraisal.

    PubMed

    Gossette, R L; O'Brien, R M

    1993-03-01

    Proponents of rational-emotive therapy (RET) advocate its use within the school curriculum to forestall future maladjustment through the early detection and eradication of irrational beliefs. A review of 33 unpublished dissertations and four published reports found RET effective in about 25% of comparisons with wait-list, placebo, and other treatment conditions. The major effects of RET were changes in scores on self-report measures of irrational beliefs, less on emotional distress, and little or no change in behavior; essentially the same pattern of effects previously found in a similar analysis of RET in adult populations. Little justification was found for continued use of RET in schools.

  1. A National Survey of Opinions on Country Life in America: The Unpublished Data from the Roosevelt Commission on Country Life (1908).

    ERIC Educational Resources Information Center

    Jones, Thomas B.; Larson, Olaf F.

    Utilizing unpublished data derived from the Roosevelt Commission on Country Life (1908), national summary reports of a 12-item questionnaire were examined and compared with the commission's published report. For purposes of analysis, the 12 questions were grouped as: (1) economic concerns, (2) farm labor, (3) services, (4) quality of life, and (5)…

  2. A geo-coded inventory of anophelines in the Afrotropical Region south of the Sahara: 1898-2016.

    PubMed

    Kyalo, David; Amratia, Punam; Mundia, Clara W; Mbogo, Charles M; Coetzee, Maureen; Snow, Robert W

    2017-01-01

    Background : Understanding the distribution of anopheline vectors of malaria is an important prelude to the design of national malaria control and elimination programmes. A single, geo-coded continental inventory of anophelines using all available published and unpublished data has not been undertaken since the 1960s. Methods : We have searched African, European and World Health Organization archives to identify unpublished reports on anopheline surveys in 48 sub-Saharan Africa countries. This search was supplemented by identification of reports that formed part of post-graduate theses, conference abstracts, regional insecticide resistance databases and more traditional bibliographic searches of peer-reviewed literature. Finally, a check was made against two recent repositories of dominant malaria vector species locations ( circa 2,500). Each report was used to extract information on the survey dates, village locations (geo-coded to provide a longitude and latitude), sampling methods, species identification methods and all anopheline species found present during the survey. Survey records were collapsed to a single site over time.    Results : The search strategy took years and resulted in 13,331 unique, geo-coded survey locations of anopheline vector occurrence between 1898 and 2016. A total of 12,204 (92%) sites reported the presence of 10 dominant vector species/sibling species; 4,473 (37%) of these sites were sampled since 2005. 4,442 (33%) sites reported at least one of 13 possible secondary vector species; 1,107 (25%) of these sites were sampled since 2005. Distributions of dominant and secondary vectors conform to previous descriptions of the ecological ranges of these vectors. Conclusion : We have assembled the largest ever geo-coded database of anophelines in Africa, representing a legacy dataset for future updating and identification of knowledge gaps at national levels. The geo-coded database is available on Harvard Dataverse as a reference source for African national malaria control programmes planning their future control and elimination strategies.

  3. A geo-coded inventory of anophelines in the Afrotropical Region south of the Sahara: 1898-2016

    PubMed Central

    Kyalo, David; Amratia, Punam; Mundia, Clara W.; Mbogo, Charles M.; Coetzee, Maureen; Snow, Robert W.

    2017-01-01

    Background: Understanding the distribution of anopheline vectors of malaria is an important prelude to the design of national malaria control and elimination programmes. A single, geo-coded continental inventory of anophelines using all available published and unpublished data has not been undertaken since the 1960s. Methods: We have searched African, European and World Health Organization archives to identify unpublished reports on anopheline surveys in 48 sub-Saharan Africa countries. This search was supplemented by identification of reports that formed part of post-graduate theses, conference abstracts, regional insecticide resistance databases and more traditional bibliographic searches of peer-reviewed literature. Finally, a check was made against two recent repositories of dominant malaria vector species locations ( circa 2,500). Each report was used to extract information on the survey dates, village locations (geo-coded to provide a longitude and latitude), sampling methods, species identification methods and all anopheline species found present during the survey. Survey records were collapsed to a single site over time.    Results: The search strategy took years and resulted in 13,331 unique, geo-coded survey locations of anopheline vector occurrence between 1898 and 2016. A total of 12,204 (92%) sites reported the presence of 10 dominant vector species/sibling species; 4,473 (37%) of these sites were sampled since 2005. 4,442 (33%) sites reported at least one of 13 possible secondary vector species; 1,107 (25%) of these sites were sampled since 2005. Distributions of dominant and secondary vectors conform to previous descriptions of the ecological ranges of these vectors. Conclusion: We have assembled the largest ever geo-coded database of anophelines in Africa, representing a legacy dataset for future updating and identification of knowledge gaps at national levels. The geo-coded database is available on Harvard Dataverse as a reference source for African national malaria control programmes planning their future control and elimination strategies. PMID:28884158

  4. Systematic review on the recurrence of postoperative nausea and vomiting after a first episode in the recovery room – implications for the treatment of PONV and related clinical trials

    PubMed Central

    Eberhart, Leopold HJ; Frank, Silke; Lange, Henning; Morin, Astrid M; Scherag, André; Wulf, Hinnerk; Kranke, Peter

    2006-01-01

    Background Despite the presence of a plethora of publications on the prevention of postoperative nausea and vomiting (PONV) only little is known how to treat established symptoms. Besides the high effort of performing these efficacy trials (much more patients must give their consent than are actually included in a study) and ethical concerns, little is known about the rate of re-occurring PONV/vomiting after placebo. As a consequence investigators will have difficulties defining a clinically relevant effect for the new treatment which is crucial for any planning. A quantitative systematic review was performed in order to provide more reliable estimates of the incidence of re-occurring PONV/vomiting after placebo and to help investigators defining a clinically relevant treatment effect. Methods A systematic search of the literature was performed using an extended search strategy of a previous review. Data on the recurrence of PONV (any nausea or emetic symptom) and vomiting (retching or vomiting) was extracted from published reports treating PONV with placebo and unpublished results from two observational trials where no treatment was given. A nonlinear random effects model was used to calculate estimates of the recurrence of symptoms and their 95%-confidence intervals (95%-CI). Results A total of 29 trials (including the unpublished data) were eligible for the calculations. Depending on the length of observation after administering placebo or no treatment the recurrence rate of PONV was between 65% (95%-CI: 53%...75%) and 84% (95%-CI: 73%...91%) and that of vomiting was between 65% (95%-CI: 44%...81%) and 78% (95%-CI: 59%...90%). Conclusion Almost all trials showed a considerable and consistently high rate of recurrence of emetic symptoms after placebo highlighting the need for a consequent antiemetic treatment. Future (placebo) controlled efficacy trials may use the presented empirical estimates for defining clinically relevant effects and for statistical power considerations. PMID:17166262

  5. Field-Induced Texturing of Ceramic Materials for Unparalleled Properties

    DTIC Science & Technology

    2017-03-01

    research for materials-by- design and advanced processing. Invited talk; 17th International Conference on Experimental Mechanics; 2016 Jul; Rhodes...material that could potentially be textured despite its diamagnetic nature. Predictive DFT modeling and experimental testing methods were designed ...presented at the Mater Science Forum; 2007 (unpublished). 71. Sugiyama T, Tahashi M, Sassa K, Asai S. The control of crystal orientation in non -magnetic

  6. Past and present aquatic habitats and fish populations of the Yazoo-Mississippi Delta

    Treesearch

    M.D. Bryant

    2010-01-01

    The goal of this review and synthesis of the literature, published and unpublished, is to describe the major processes that shape and influence the aquatic habitats and fish communities in the Yazoo-Mississippi Delta (YMD) and to outline a program of research. The YMD is influenced by the large geographic and temporal scales of the Mississippi River watershed. It...

  7. The Shock and Vibration Digest, Volume 17, Number 12

    DTIC Science & Technology

    1985-12-01

    of the con- engineering guidelines is presented. Includ - tinuous analog signals represented digitally ed are details related to general test tailor...into current technology in more S. than 150 topic areas. Review articles include technical information from articles, reports, and unpublished...Turbulence was actually produce the noise. One is the once thought to be a random and chaotic traditional view that the turbulence is .. motion of

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mills, Evan; Jones, Richard B.

    Large yet infrequent disruptions of electrical power can impact tens of millions of people in a single event, triggering significant economic damages, portions of which are insured. Small and frequent events are also significant in the aggregate. This article explores the role that insurance claims data can play in better defining the broader economic impacts of grid disruptions in the U.S. context. We developed four case studies, using previously unpublished data for specific actual grid disruptions. The cases include the 1977 New York City blackout, the 2003 Northeast blackout, multi-year national annual lightning-related electrical damage and multi-year national line-disturbance events.more » Insured losses represent between 3 and 64 per cent of total loss costs across the case studies. Here, the household sector emerges as a larger locus of costs than indicated in previous studies, and short-lived events emerge as important sources of loss costs.« less

  9. An insurance perspective on U.S. electric grid disruption costs

    DOE PAGES

    Mills, Evan; Jones, Richard B.

    2016-10-12

    Large yet infrequent disruptions of electrical power can impact tens of millions of people in a single event, triggering significant economic damages, portions of which are insured. Small and frequent events are also significant in the aggregate. This article explores the role that insurance claims data can play in better defining the broader economic impacts of grid disruptions in the U.S. context. We developed four case studies, using previously unpublished data for specific actual grid disruptions. The cases include the 1977 New York City blackout, the 2003 Northeast blackout, multi-year national annual lightning-related electrical damage and multi-year national line-disturbance events.more » Insured losses represent between 3 and 64 per cent of total loss costs across the case studies. Here, the household sector emerges as a larger locus of costs than indicated in previous studies, and short-lived events emerge as important sources of loss costs.« less

  10. Source Materials and the Library: The Dispersion of the Beaumont Papers

    PubMed Central

    Pizer, Irwin H.

    1964-01-01

    The author discusses the confusion, attributable to misleading references, which long obscured the location of the main portion of the William Beaumont papers. The collection was previously thought to be in the National Library of Medicine, but it is actually housed in the Washington University School of Medicine Library. This has been clarified by the discovery of a series of previously unpublished letters of Sir William Osler, as well as by other newly found materials. The history of the Washington University School of Medicine Library is reviewed, and the facts relating to the disposition of the Beaumont collection in that library rather than the National Library of Medicine are told. Also considered are some of the problems which the dispersion of documentary source materials creates for the scholar. With the Beaumont papers as a case in point, various locations of such materials are cited, and their contents briefly noted. PMID:14119306

  11. Systematic Reviews Published in Emergency Medicine Journals Do Not Routinely Search Clinical Trials Registries: A Cross-Sectional Analysis.

    PubMed

    Keil, Lukas G; Platts-Mills, Timothy F; Jones, Christopher W

    2015-10-01

    Publication bias compromises the validity of systematic reviews. This problem can be addressed in part through searching clinical trials registries to identify unpublished studies. This study aims to determine how often systematic reviews published in emergency medicine journals include clinical trials registry searches. We identified all systematic reviews published in the 6 highest-impact emergency medicine journals between January 1 and December 31, 2013. Systematic reviews that assessed the effects of an intervention were further examined to determine whether the authors described searching a clinical trials registry and whether this search identified relevant unpublished studies. Of 191 articles identified through PubMed search, 80 were confirmed to be systematic reviews. Our sample consisted of 41 systematic reviews that assessed a specific intervention. Eight of these 41 (20%) searched a clinical trials registry. For 4 of these 8 reviews, the registry search identified at least 1 relevant unpublished study. Systematic reviews published in emergency medicine journals do not routinely include searches of clinical trials registries. By helping authors identify unpublished trial data, the addition of registry searches may improve the validity of systematic reviews. Copyright © 2014 American College of Emergency Physicians. Published by Elsevier Inc. All rights reserved.

  12. An inventory of published and unpublished fluvial-sediment data for California, 1956-70

    USGS Publications Warehouse

    Porterfield, George

    1972-01-01

    This inventory was prepared to provide a convenient reference to published and unpublished fluvial-sediment data for water years 1956-70, and updates substantially previous inventories. Sediment stations are listed in downstream order, and an alphabetical list of stations is also included. Figure 1 shows the approximate location of sediment stations in California. Most of the fluvial-sediment data in California were collected by the U.S. Geological Survey, under cooperative agreements with the following Federal, State, and local agencies: California Department of Water Resources, California Department of Navigation and Ocean Development, California Department of Fish and Game, Bolinas Harbor District, Monterey County Flood Control and Water Conservation District, Orange County Flood Control District, Riverside County Flood Control and Water Conservation District, San Diego County Department of Sanitation and Flood Control, San Luis Obispo County, San Mateo County, Santa Clara County Flood Control and Water District, Santa Cruz County Flood Control and Water Conservation District, Santa Cruz, city of, University of California, Ventura County Flood Control District, Forest Service, U.S. Department of Agriculture, Soil Conservation Service, U.S. Department of Agriculture, Corps of Engineers, U.S. Army, Bureau of Reclamation, U.S. Department of the Interior, National Park Service, U.S. Department of the Interior. This report was prepared by the Geological Survey under the general supervision of R. Stanley Lord, district chief in charge of water-resources investigations in California.

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Richard F. Shand

    The Gordon Research Conference (GRC) on 2003 Archaea: Ecology, Metabolism and Molecular Biology was held at Proctor Academy, Andover, NH from August 3-8, 2003. The Conference was well-attended with 150 participants (attendees list attached). The attendees represented the spectrum of endeavor in this field coming from academia, industry, and government laboratories, both U.S. and foreign scientists, senior researchers, young investigators, and students. In designing the formal speakers program, emphasis was placed on current unpublished research and discussion of the future target areas in this field. There was a conscious effort to stimulate lively discussion about the key issues in themore » field today. Time for formal presentations was limited in the interest of group discussions. In order that more scientists could communicate their most recent results, poster presentation time was scheduled. Attached is a copy of the formal schedule and speaker program and the poster program. In addition to these formal interactions, ''free time'' was scheduled to allow informal discussions. Such discussions are fostering new collaborations and joint efforts in the field. I want to personally thank you for your support of this Conference. As you know, in the interest of promoting the presentation of unpublished and frontier-breaking research, Gordon Research Conferences does not permit publication of meeting proceedings. If you wish any further details, please feel free to contact me. Thank you, Dr. Richard F. Shand, 2003 Conference Chair.« less

  14. An updated Holocene sea-level curve for the Delaware coast

    USGS Publications Warehouse

    Nikitina, D.L.; Pizzuto, J.E.; Schwimmer, R.A.; Ramsey, K.W.

    2000-01-01

    We present an updated Holocene sea-level curve for the Delaware coast based on new calibrations of 16 previously published radiocarbon dates (Kraft, 1976; Belknap and Kraft, 1977) and 22 new radiocarbon dates of basal peat deposits. A review of published and unpublished 137Cs and 210Pb analyses, and tide gauge data provide the basis for evaluating shorter-term (102 yr) sea-level trends. Paleosea-level elevations for the new basal peat samples were determined from the present vertical zonation of marsh plants relative to mean high water along the Delaware coast and the composition of plant fossils and foraminifera. Current trends in tidal range along the Delaware coast were used to reduce elevations from different locations to a common vertical datum of mean high water at Breakwater Harbor, Delaware. The updated curve is similar to Belknap and Kraft's [J. Sediment. Petrol., 47 (1977) 610-629] original sea-level curve from 12,000 to about 2000 yr BP. The updated curve documents a rate of sea-level rise of 0.9 mm/yr from 1250 yr BP to present (based on 11 dates), in good agreement with other recent sea-level curves from the northern and central U.S. Atlantic coast, while the previous curve documents rates of about 1.3 mm/yr (based on 4 dates). The precision of both estimates, however, is very low, so the significance of these differences is uncertain. A review of 210Pb and 137Cs analyses from salt marshes of Delaware indicates average marsh accretion rates of 3 mm/yr for the last 100 yr, in good agreement with shorter-term estimates of sea-level rise from tide gauge records. ?? 2000 Elsevier Science B.V.

  15. Orbit Determination Issues for Libration Point Orbits

    NASA Technical Reports Server (NTRS)

    Beckman, Mark; Bauer, Frank (Technical Monitor)

    2002-01-01

    Libration point mission designers require knowledge of orbital accuracy for a variety of analyses including station keeping control strategies, transfer trajectory design, and formation and constellation control. Past publications have detailed orbit determination (OD) results from individual libration point missions. This paper collects both published and unpublished results from four previous libration point missions (ISEE (International Sun-Earth Explorer) -3, SOHO (Solar and Heliospheric Observatory), ACE (Advanced Composition Explorer) and MAP (Microwave Anisotropy Probe)) supported by Goddard Space Flight Center's Guidance, Navigation & Control Center. The results of those missions are presented along with OD issues specific to each mission. All past missions have been limited to ground based tracking through NASA ground sites using standard range and Doppler measurement types. Advanced technology is enabling other OD options including onboard navigation using seaboard attitude sensors and the use of the Very Long Baseline Interferometry (VLBI) measurement Delta Differenced One-Way Range (DDOR). Both options potentially enable missions to reduce coherent dedicated tracking passes while maintaining orbital accuracy. With the increased projected loading of the DSN (Deep Space Network), missions must find alternatives to the standard OD scenario.

  16. Density-driven transport process following the seawater indundation of the freshwater lens of the island of Baltrum, Germany

    NASA Astrophysics Data System (ADS)

    Post, Vincent E. A.; Houben, Georg J.

    2017-04-01

    Due to the growing vulnerability of low-lying coastal zones to flooding by seawater, there is a need for more studies of the impact of inundations on fresh groundwater resources. We present previously unpublished data collected on the island of Baltrum following a devastating storm in 1962, which uniquely show the impact of seawater inundation on a freshwater lens in a siliciclastic aquifer. The field data show that elevated salinities persisted for at least 4 years at the measurement depths of 4 and 6 m, and at least for 6 years at greater depths. Numerical models confirm the importance of density-driven salt fingering. Models that did not consider density effects failed to simulate the observed breakthrough curves. Transient recharge, model dimension and lateral flow modify the details of the simulation results, but in all models density-driven flow dominates the overall system behaviour. The sequestration of intruded seawater into the deeper parts of the flow system, prolongs recovery and enhances the risk of upconing when pumping is resumed too early.

  17. Microplasmas for chemical analysis: analytical tools or research toys?

    NASA Astrophysics Data System (ADS)

    Karanassios, Vassili

    2004-07-01

    An overview of the activities of the research groups that have been involved in fabrication, development and characterization of microplasmas for chemical analysis over the last few years is presented. Microplasmas covered include: miniature inductively coupled plasmas (ICPs); capacitively coupled plasmas (CCPs); microwave-induced plasmas (MIPs); a dielectric barrier discharge (DBD); microhollow cathode discharge (MCHD) or microstructure electrode (MSE) discharges, other microglow discharges (such as those formed between "liquid" electrodes); microplasmas formed in micrometer-diameter capillary tubes for gas chromatography (GC) or high-performance liquid chromatography (HPLC) applications, and a stabilized capacitive plasma (SCP) for GC applications. Sample introduction into microplasmas, in particular, into a microplasma device (MPD), battery operation of a MPD and of a mini- in-torch vaporization (ITV) microsample introduction system for MPDs, and questions of microplasma portability for use on site (e.g., in the field) are also briefly addressed using examples of current research. To emphasize the significance of sample introduction into microplasmas, some previously unpublished results from the author's laboratory have also been included. And an overall assessment of the state-of-the-art of analytical microplasma research is provided.

  18. Ecological Genomics of Marine Picocyanobacteria†

    PubMed Central

    Scanlan, D. J.; Ostrowski, M.; Mazard, S.; Dufresne, A.; Garczarek, L.; Hess, W. R.; Post, A. F.; Hagemann, M.; Paulsen, I.; Partensky, F.

    2009-01-01

    Summary: Marine picocyanobacteria of the genera Prochlorococcus and Synechococcus numerically dominate the picophytoplankton of the world ocean, making a key contribution to global primary production. Prochlorococcus was isolated around 20 years ago and is probably the most abundant photosynthetic organism on Earth. The genus comprises specific ecotypes which are phylogenetically distinct and differ markedly in their photophysiology, allowing growth over a broad range of light and nutrient conditions within the 45°N to 40°S latitudinal belt that they occupy. Synechococcus and Prochlorococcus are closely related, together forming a discrete picophytoplankton clade, but are distinguishable by their possession of dissimilar light-harvesting apparatuses and differences in cell size and elemental composition. Synechococcus strains have a ubiquitous oceanic distribution compared to that of Prochlorococcus strains and are characterized by phylogenetically discrete lineages with a wide range of pigmentation. In this review, we put our current knowledge of marine picocyanobacterial genomics into an environmental context and present previously unpublished genomic information arising from extensive genomic comparisons in order to provide insights into the adaptations of these marine microbes to their environment and how they are reflected at the genomic level. PMID:19487728

  19. ["The grandest hero who has ever lived": an unpublished letter written by Florence Nightingale about Garibaldi].

    PubMed

    Festini, Filippo; Giusti, Francesca

    2012-01-01

    In the year of the 150th anniversary of the Unity of Italy, Italian nurses cannot forget that Florence Nightingale herself, founder of modern Nursing , was a fervid support of the Risorgimento and of Italian unity. An unpublished letter, signed by her and conserved in the State archives of Pistoia, illustrates her feelings about the process of unity under way in the country where she was born.

  20. The Swift-BAT Hard X-Ray Transient Monitor

    NASA Technical Reports Server (NTRS)

    Krimm, H. A.; Holland, S. T.; Corbet, R. H. D.; Pearlman, A. B.; Romano, P.; Kennea, J. A.; Bloom, J. S.; Barthelmy, S. D.; Baumgartner, W. H.; Cummings, J. R.; hide

    2013-01-01

    The Swift/Burst Alert Telescope (BAT) hard X-ray transient monitor provides near real-time coverage of the X-ray sky in the energy range 15-50 keV. The BAT observes 88% of the sky each day with a detection sensitivity of 5.3 mCrab for a full-day observation and a time resolution as fine as 64 s. The three main purposes of the monitor are (1) the discovery of new transient X-ray sources, (2) the detection of outbursts or other changes in the flux of known X-ray sources, and (3) the generation of light curves of more than 900 sources spanning over eight years. The primary interface for the BAT transient monitor is a public Web site. Between 2005 February 12 and 2013 April 30, 245 sources have been detected in the monitor, 146 of them persistent and 99 detected only in outburst. Among these sources, 17 were previously unknown and were discovered in the transient monitor. In this paper, we discuss the methodology and the data processing and filtering for the BAT transient monitor and review its sensitivity and exposure.We provide a summary of the source detections and classify them according to the variability of their light curves. Finally, we review all new BAT monitor discoveries. For the new sources that are previously unpublished, we present basic data analysis and interpretations.

  1. Mapping Topological Magnetization and Magnetic Skyrmions

    NASA Astrophysics Data System (ADS)

    Chess, Jordan J.

    A 2014 study by the US Department of Energy conducted at Lawrence Berkeley National Laboratory estimated that U.S. data centers consumed 70 billion kWh of electricity. This represents about 1.8% of the total U.S. electricity consumption. Putting this in perspective 70 billion kWh of electricity is the equivalent of roughly 8 big nuclear reactors, or around double the nation's solar panel output. Developing new memory technologies capable of reducing this power consumption would be greatly beneficial as our demand for connectivity increases in the future. One newly emerging candidate for an information carrier in low power memory devices is the magnetic skyrmion. This magnetic texture is characterized by its specific non-trivial topology, giving it particle-like characteristics. Recent experimental work has shown that these skyrmions can be stabilized at room temperature and moved with extremely low electrical current densities. This rapidly developing field requires new measurement techniques capable of determining the topology of these textures at greater speed than previous approaches. In this dissertation, I give a brief introduction to the magnetic structures found in Fe/Gd multilayered systems. I then present newly developed techniques that streamline the analysis of Lorentz Transmission Electron Microscopy (LTEM) data. These techniques are then applied to further the understanding of the magnetic properties of these Fe/Gd based multilayered systems. This dissertation includes previously published and unpublished co-authored material.

  2. THE SWIFT/BAT HARD X-RAY TRANSIENT MONITOR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krimm, H. A.; Holland, S. T.; Corbet, R. H. D.

    2013-11-01

    The Swift/Burst Alert Telescope (BAT) hard X-ray transient monitor provides near real-time coverage of the X-ray sky in the energy range 15-50 keV. The BAT observes 88% of the sky each day with a detection sensitivity of 5.3 mCrab for a full-day observation and a time resolution as fine as 64 s. The three main purposes of the monitor are (1) the discovery of new transient X-ray sources, (2) the detection of outbursts or other changes in the flux of known X-ray sources, and (3) the generation of light curves of more than 900 sources spanning over eight years. Themore » primary interface for the BAT transient monitor is a public Web site. Between 2005 February 12 and 2013 April 30, 245 sources have been detected in the monitor, 146 of them persistent and 99 detected only in outburst. Among these sources, 17 were previously unknown and were discovered in the transient monitor. In this paper, we discuss the methodology and the data processing and filtering for the BAT transient monitor and review its sensitivity and exposure. We provide a summary of the source detections and classify them according to the variability of their light curves. Finally, we review all new BAT monitor discoveries. For the new sources that are previously unpublished, we present basic data analysis and interpretations.« less

  3. Health and Extended Worklife. An Information Paper Prepared for Use by the Special Committee on Aging. United States Senate, Ninety-Ninth Congress, First Session.

    ERIC Educational Resources Information Center

    Newquist, Deborah D.

    This report presents information about the health status of older workers as it relates to extended work lives. The report contains unpublished data on the health status of civilian, noninstitutionalized middle-aged and older adults; the data are disaggregated so that narrow age differences within the older population can be observed and are…

  4. Environmental Inventory Upper Cumberland River, Harlan, Kentucky.

    DTIC Science & Technology

    1981-12-01

    presents a vicini- ty map for the area. The nearest major city is Knoxville, Tennessee, approxi- mately 140 miles southwest of the study area. Corbin...Harlan study area lies within the Cumberland Mountains section of the Ap- palachian Plateau Physiographic Province. This section has a topography typi...or unpublished mapping was available, instead a specific soils survey of the study area was implemented by the Soil Conser- vation Service (SCS) office

  5. Woody detritus density and density reduction factors for tree species in the United States: a synthesis

    Treesearch

    Mark E. Harmon; Christopher W. Woodall; Becky Fasth; Jay Sexton

    2008-01-01

    This report presents a synthesis of published and unpublished data on woody detritus density as a step toward improving estimates of coarse woody detritus (CWD) and fine woody detritus (FWD) biomass across the forests of the United States. In the case of CWD, 88 species were found to have data on densities for five decay classes that had been published and/or collected...

  6. 'White matter connectivity and Internet gaming disorder' and broader considerations in the field.

    PubMed

    Tam, Philip G E

    2017-01-01

    This invited commentary on the paper 'White Matter Connectivity and Internet gaming disorder' by Jeong et al. (unpublished) looks at the implications and importance of the MRI findings in the present study-one of the largest to date-and also considers the broader developments of neuroimaging within the complex, emerging field of 'Internet psychology' and problematic Internet usage. © 2015 Society for the Study of Addiction.

  7. Efficacy of killed whole-parasite vaccines in the prevention of leishmaniasis: a meta-analysis.

    PubMed

    Noazin, Sassan; Khamesipour, Ali; Moulton, Lawrence H; Tanner, Marcel; Nasseri, Kiumarss; Modabber, Farrokh; Sharifi, Iraj; Khalil, E A G; Bernal, Ivan Dario Velez; Antunes, Carlos M F; Smith, Peter G

    2009-07-30

    Despite decades of investigation in countries on three continents, an efficacious vaccine against Leishmania infections has not been developed. Although some indication of protection was observed in some of the controlled trials conducted with "first-generation" whole, inactivated Leishmania parasite vaccines, convincing evidence of protection was lacking. After reviewing all previously published or unpublished randomized, controlled field efficacy clinical trials of prophylactic candidate vaccines, a meta-analysis of qualified trials was conducted to evaluate whether there was some evidence of protection revealed by considering the results of all trials together. The findings indicate that the whole-parasite vaccine candidates tested do not confer significant protection against human leishmaniasis.

  8. Map and digital database of sedimentary basins and indications of petroleum in the Central Alaska Province

    USGS Publications Warehouse

    Troutman, Sandra M.; Stanley, Richard G.

    2003-01-01

    This database and accompanying text depict historical and modern reported occurrences of petroleum both in wells and at the surface within the boundaries of the Central Alaska Province. These data were compiled from previously published and unpublished sources and were prepared for use in the 2002 U.S. Geological Survey petroleum assessment of Central Alaska, Yukon Flats region. Indications of petroleum are described as oil or gas shows in wells, oil or gas seeps, or outcrops of oil shale or oil-bearing rock and include confirmed and unconfirmed reports. The scale of the source map limits the spatial resolution (scale) of the database to 1:2,500,000 or smaller.

  9. An investigation into exoplanet transits and uncertainties

    NASA Astrophysics Data System (ADS)

    Ji, Y.; Banks, T.; Budding, E.; Rhodes, M. D.

    2017-06-01

    A simple transit model is described along with tests of this model against published results for 4 exoplanet systems (Kepler-1, 2, 8, and 77). Data from the Kepler mission are used. The Markov Chain Monte Carlo (MCMC) method is applied to obtain realistic error estimates. Optimisation of limb darkening coefficients is subject to data quality. It is more likely for MCMC to derive an empirical limb darkening coefficient for light curves with S/N (signal to noise) above 15. Finally, the model is applied to Kepler data for 4 Kepler candidate systems (KOI 760.01, 767.01, 802.01, and 824.01) with previously unpublished results. Error estimates for these systems are obtained via the MCMC method.

  10. Documentation for the machine-readable version of the Smithsonian Astrophysical Observatory Star catalogue (SAO) version 1984

    NASA Technical Reports Server (NTRS)

    Roman, N. G.; Warren, W. H., Jr.

    1984-01-01

    An updated, corrected and extended machine readable version of the Smithsonian Astrophysical Observatory star catalog (SAO) is described. Published and unpublished errors discovered in the previous version have been corrected, and multiple star and supplemental BD identifications added to stars where more than one SAO entry has the same Durchmusterung number. Henry Draper Extension (HDE) numbers have been added for stars found in both volumes of the extension. Data for duplicate SAO entries (those referring to the same star) have been blanked out, but the records themselves have been retained and flagged so that sequencing and record count are identical to the published catalog.

  11. Heightened sensitivity of the esophagus to radiation in a patient with AIDS.

    PubMed

    Costleigh, B J; Miyamoto, C T; Micaily, B; Brady, L W

    1995-05-01

    Esophageal stricture is an uncommon complication in HIV-negative patients treated with radiation to the chest for lung cancer. There have been a number of recent reports on the association of cancer and HIV-positive patients, as well as a greater sensitivity to radiation therapy of the mucous membranes in HIV/AIDS patients. This article reflects a review of the literature on the risk of major complications and morbidity of the esophagus in HIV+/AIDS patients whose chests are treated with radiation for lung cancer. Included is a report of a previously unpublished case of an early and severe esophageal reaction to radiation therapy in an AIDS patient.

  12. Catastrophic antiphospholipid syndrome during pregnancy and puerperium: maternal and fetal characteristics of 15 cases

    PubMed Central

    Gómez‐Puerta, José A; Cervera, Ricard; Espinosa, Gerard; Asherson, Ronald A; García‐Carrasco, Mario; da Costa, Izaias P; Andrade, Danieli C O; Borba, Eduardo F; Makatsaria, Alexander; Bucciarelli, Silvia; Ramos‐Casals, Manuel; Font, Josep

    2007-01-01

    Background The catastrophic variant of the antiphospholipid syndrome (APS) is a life‐threatening form of presentation of this syndrome that can be triggered by several factors. Aim To describe the characteristics of patients who developed catastrophic APS triggered during pregnancy and puerperium. Methods A review of the first 255 cases collected in the website‐based “CAPS Registry” was undertaken. Three new and unpublished cases of catastrophic APS developed during pregnancy and puerperium were added. Results Fifteen cases were identified. The mean (range) age was 27 (17–38) years. Most patients had a previous unsuccessful obstetric history. In 7 of 14 (50%) cases with available medical history, the catastrophic APS appeared during pregnancy, in 6 (43%) during the puerperium and in 1 (7%) after curettage for a fetal death. The main clinical and serological characteristics were similar to those patients with catastrophic APS triggered by other factors, except for a history of a higher prevalence of previous abortions (p<0.01). Several specific features were found, including the HELLP (haemolysis, elevated liver enzymes, low platelets) syndrome in 8 (53%) patients, placental infarctions in 4 (27%) patients, and pelvic vein thrombosis and myometrium thrombotic microangiopathy in 1 (7%) patient each. Mortality rate was high for the mothers (46%), and for the babies (54%). Conclusions It is important to consider the possibility of the development of catastrophic APS in those patients with signs of HELLP syndrome and multiorgan failure during pregnancy or puerperium, especially in those patients with previous history of abortions and/or thrombosis. PMID:17223653

  13. Grey literature in systematic reviews: a cross-sectional study of the contribution of non-English reports, unpublished studies and dissertations to the results of meta-analyses in child-relevant reviews.

    PubMed

    Hartling, Lisa; Featherstone, Robin; Nuspl, Megan; Shave, Kassi; Dryden, Donna M; Vandermeer, Ben

    2017-04-19

    Systematic reviews (SRs) are an important source of information about healthcare interventions. A key component of a well-conducted SR is a comprehensive literature search. There is limited evidence on the contribution of non-English reports, unpublished studies, and dissertations and their impact on results of meta-analyses. Our sample included SRs from three Cochrane Review Groups: Acute Respiratory Infections (ARI), Infectious Diseases (ID), Developmental Psychosocial and Learning Problems (DPLP) (n = 129). Outcomes included: 1) proportion of reviews that searched for and included each study type; 2) proportion of relevant studies represented by each study type; and 3) impact on results and conclusions of the primary meta-analysis for each study type. Most SRs searched for non-English studies; however, these were included in only 12% of reviews and represented less than 5% of included studies. There was a change in results in only four reviews (total sample = 129); in two cases the change did not have an impact on the statistical or clinical significance of results. Most SRs searched for unpublished studies but the majority did not include these (only 6%) and they represented 2% of included studies. In most cases the impact of including unpublished studies was small; a substantial impact was observed in one case that relied solely on unpublished data. Few reviews in ARI (9%) and ID (3%) searched for dissertations compared to 65% in DPLP. Overall, dissertations were included in only nine SRs and represented less than 2% of included studies. In the majority of cases the change in results was negligible or small; in the case where a large change was noted, the estimate was more conservative without dissertations. The majority of SRs searched for non-English and unpublished studies; however, these represented a small proportion of included studies and rarely impacted the results and conclusions of the review. Inclusion of these study types may have an impact in situations where there are few relevant studies, or where there are questionable vested interests in the published literature. We found substantial variation in whether SRs searched for dissertations; in most reviews that included dissertations, these had little impact on results.

  14. Parsing glucose entry into the brain: novel findings obtained with enzyme-based glucose biosensors.

    PubMed

    Kiyatkin, Eugene A; Wakabayashi, Ken T

    2015-01-21

    Extracellular levels of glucose in brain tissue reflect dynamic balance between its gradient-dependent entry from arterial blood and its use for cellular metabolism. In this work, we present several sets of previously published and unpublished data obtained by using enzyme-based glucose biosensors coupled with constant-potential high-speed amperometry in freely moving rats. First, we consider basic methodological issues related to the reliability of electrochemical measurements of extracellular glucose levels in rats under physiologically relevant conditions. Second, we present data on glucose responses induced in the nucleus accumbens (NAc) by salient environmental stimuli and discuss the relationships between local neuronal activation and rapid glucose entry into brain tissue. Third, by presenting data on changes in NAc glucose induced by intravenous and intragastric glucose delivery, we discuss other mechanisms of glucose entry into the extracellular domain following changes in glucose blood concentrations. Lastly, by showing the pattern of NAc glucose fluctuations during glucose-drinking behavior, we discuss the relationships between "active" and "passive" glucose entry to the brain, its connection to behavior-related metabolic activation, and the possible functional significance of these changes in behavioral regulation. These data provide solid experimental support for the "neuronal" hypothesis of neurovascular coupling, which postulates the critical role of neuronal activity in rapid regulation of vascular tone, local blood flow, and entry of glucose and oxygen to brain tissue to maintain active cellular metabolism.

  15. VizieR Online Data Catalog: VRIJHK photometry of 3C 279 (Sandrinelli+, 2016)

    NASA Astrophysics Data System (ADS)

    Sandrinelli, A.; Covino, S.; Dotti, M.; Treves, A.

    2016-07-01

    The starting point of the present investigation is the VRIJHK photometric observations obtained with the robotic Rapid Eye Mounting telescope (REM) at La Silla, which are described in detail in Sandrinelli et al. 2014 (cat. J/A+A/562/A79). We add to the data available in the above mentioned paper the REM photometry of 3C 279 (see Table2), which is unpublished thus far. (2 data files).

  16. Geology of the Cape Mendocino, Eureka, Garberville, and Southwestern Part of the Hayfork 30 x 60 Minute Quadrangles and Adjacent Offshore Area, Northern California

    USGS Publications Warehouse

    McLaughlin, Robert J.; Ellen, S.D.; Blake, M.C.; Jayko, Angela S.; Irwin, W.P.; Aalto, K.R.; Carver, G.A.; Clarke, S.H.; Barnes, J.B.; Cecil, J.D.; Cyr, K.A.

    2000-01-01

    Introduction These geologic maps and accompanying structure sections depict the geology and structure of much of northwestern California and the adjacent continental margin. The map area includes the Mendocino triple junction, which is the juncture of the North American continental plate with two plates of the Pacific ocean basin. The map area also encompasses major geographic and geologic provinces of northwestern California. The maps incorporate much previously unpublished geologic mapping done between 1980 and 1995, as well as published mapping done between about 1950 and 1978. To construct structure sections to mid-crustal depths, we integrate the surface geology with interpretations of crustal structure based on seismicity, gravity and aeromagnetic data, offshore structure, and seismic reflection and refraction data. In addition to describing major geologic and structural features of northwestern California, the geologic maps have the potential to address a number of societally relevant issues, including hazards from earthquakes, landslides, and floods and problems related to timber harvest, wildlife habitat, and changing land use. All of these topics will continue to be of interest in the region, as changing land uses and population density interact with natural conditions. In these interactions, it is critical that the policies and practices affecting man and the environment integrate an adequate understanding of the geology. This digital map database, compiled from previously published and unpublished data, and new mapping by the authors, represents the general distribution of bedrock and surficial deposits in the mapped area. Together with the accompanying text file (ceghmf.ps, ceghmf.pdf, ceghmf.txt), it provides current information on the geologic structure and stratigraphy of the area covered. The database delineates map units that are identified by general age and lithology following the stratigraphic nomenclature of the U.S. Geological Survey. The scale of the source maps limits the spatial resolution (scale) of the database to 1:100,000 or smaller.

  17. Organizing for Effective Joint Warfare: A Deductive Analysis of U.S. Armed Forces Joint Doctrine

    DTIC Science & Technology

    1993-06-18

    8217, Unpublished SAMS Monogram , (U.S. Army Command and General Staff College, Fort Leavenworth, KS: i988) p. 25. 3. Frank 0. Hough, et al, History of...SAMS Monogram , (U.S. Army Command and General Staff College, Fort Leavenworth, KS: 1988) , p, 16 and p. 29; and William 0. Pierce, ’Span of Control and...The Operational Commandetr: Is it More Than Just a Nun:ber?", Unpublished SAMS Monogram , (U.S. Army Command and Ueneral Staff College, Fort Leavenworth

  18. Effects of management practices on grassland birds: Greater Prairie-Chicken

    USGS Publications Warehouse

    Svedarsky, W. Daniel; Toepfer, J.E.; Westemeier, R.L.; Robel, R.J.

    2003-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the breeding distribution of Greater Prairie-Chicken in the United States and southern Canada. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species’ response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species’ breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management is posted at the Web site mentioned below.

  19. Leibniz's Observations on Hydrology: An Unpublished Letter on the Great Lombardy Flood of 1705.

    PubMed

    Strickland, Lloyd; Church, Michael

    2015-01-01

    Although the historical reputation of Gottfried Wilhelm Leibniz (1646-1716) largely rests on his philosophical and mathematical work, it is widely known that he made important contributions to many of the emerging but still inchoate branches of natural science of his day. Among the many scientific papers Leibniz published during his lifetime are ones on the nascent science we now know as hydrology. While Leibniz's other scientific work has become of increasing interest to scholars in recent years, his thinking about hydrology has been neglected, despite being relatively broad in extent, including as it does papers on the 'raising of vapours' and the formation of ice, as well as the separation of salt and fresh water. That list can now be extended still further following the discovery of a previously unpublished letter of Leibniz's on the causes of the devastating Lombardy flood of October and November 1705. This letter, which will be the focus of our paper, reveals the depth of Leibniz's understanding of key hydrological processes. In it, he considers various mechanisms for the flood, such as heavy rains on high ground, underwater earthquakes, and a mountain collapse. Over the course of the paper we examine each of these mechanisms in depth, and show that Leibniz was in the vanguard of hydrological thinking. We also show that the letter contains one of the first scholarly attempts to apply aspects of the still-forming notion of the hydrological cycle to account for a flood event.

  20. The risk for cross-reactions after a cutaneous delayed-type hypersensitivity reaction to heparin preparations is independent of their molecular weight: a systematic review.

    PubMed

    Weberschock, Tobias; Meister, Anna Christina; Bohrt, Kevin; Schmitt, Jochen; Boehncke, Wolf-Henning; Ludwig, Ralf J

    2011-10-01

    Heparins are a widely used class of drugs known to cause delayed-type hypersensitivity (DTH) reactions. Recent publications indicate that the incidence of these may be higher than previously thought. To date, patient-related but no drug-related risk factors for the development of DTH reactions to heparins have been identified, although molecular weight is discussed as a potentially relevant parameter. To address this, a systematic review was conducted on the frequency of cross-reactions after DTH reactions to heparin preparations. We electronically searched MEDLINE and EMBASE, hand-searched selected journals and references, and contacted experts for unpublished data. Sixty-six publications and unpublished data of 14 patients resulted in 198 patients with 1084 tests for cross-reactivity. The primary causative agents were mostly unfractionated heparin (50%) and low molecular weight heparins (49.5%). Cross-reactions were more likely after an initial DTH reaction to unfractionated heparin than after an initial DTH reaction to low molecular weight heparin. Our findings also indicate that molecular weight does not correlate with the risk for cross-reactivity, which is in line with recent observations, indicating that different heparins have to be individually considered. The available data demonstrated the lowest overall risk for cross-reactions for pentosan polysulfate (36.4%) and fondaparinux (10.4%). In the clinical context, fondaparinux is recommended as the current best alternative when a DTH reaction occurs. © 2011 John Wiley & Sons A/S.

  1. Disorganized attachment and defense: exploring John Bowlby’s unpublished reflections

    PubMed Central

    Reisz, Samantha; Duschinsky, Robbie; Siegel, Daniel J

    2018-01-01

    ABSTRACT Main and Solomon were the first to create a formal infant Strange Situation classification of attachment disorganization. Bowlby’s reflections on the underlying psychological processes of such behaviors, however, began early in his career, including the term “disorganization.” Most of these remained unpublished but are available through the John Bowlby Archive. Bowlby saw affective experiences as the source of the attachment behavioral system’s organization and regulation, and he introduced the term “effector equipment” to describe the emergent organization of attention, expectation, affect, and behavior to orchestrate responses to the environment. In his thinking, disorganization results from threat conflict, safe haven ambiguity, and/or activation without assuagement, which interfere with coordination and integration across a behavioral system. Bowlby’s unpublished writings also amplify his published work on segregated systems and defensive exclusion. Bowlby’s insights are relevant today and can provide greater background and clarity to current work, as researchers and clinicians consider the origins, manifestations, and meaning of disorganization. PMID:28952412

  2. Geologic map and map database of northeastern San Francisco Bay region, California, [including] most of Solano County and parts of Napa, Marin, Contra Costa, San Joaquin, Sacramento, Yolo, and Sonoma Counties

    USGS Publications Warehouse

    Graymer, Russell Walter; Jones, David Lawrence; Brabb, Earl E.

    2002-01-01

    This digital map database, compiled from previously published and unpublished data, and new mapping by the authors, represents the general distribution of bedrock and surficial deposits in the mapped area. Together with the accompanying text file (nesfmf.ps, nesfmf.pdf, nesfmf.txt), it provides current information on the geologic structure and stratigraphy of the area covered. The database delineates map units that are identified by general age and lithology following the stratigraphic nomenclature of the U.S. Geological Survey. The scale of the source maps limits the spatial resolution (scale) of the database to 1:62,500 or smaller.

  3. George Herbert Mead and the Allen controversy at the University of Wisconsin.

    PubMed

    Cook, Gary A

    2007-01-01

    This essay uses previously unpublished correspondence of George Herbert Mead to tell the story of his involvement in the aftermath of a political dispute that took place at the University of Wisconsin during the years 1914-1915. It seeks thereby to clarify the historical significance of an article he published on this controversy in late 1915. Taken together with relevant information about the educational activities of William H. Allen of the New York Bureau of Municipal Research, Mead's correspondence and article throw helpful light upon his understanding of how an educational survey of a university should proceed; they also show how he went about the task of evaluating a failed attempt at such a survey. (c) 2007 Wiley Periodicals, Inc.

  4. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Spotz, William F.

    PyTrilinos is a set of Python interfaces to compiled Trilinos packages. This collection supports serial and parallel dense linear algebra, serial and parallel sparse linear algebra, direct and iterative linear solution techniques, algebraic and multilevel preconditioners, nonlinear solvers and continuation algorithms, eigensolvers and partitioning algorithms. Also included are a variety of related utility functions and classes, including distributed I/O, coloring algorithms and matrix generation. PyTrilinos vector objects are compatible with the popular NumPy Python package. As a Python front end to compiled libraries, PyTrilinos takes advantage of the flexibility and ease of use of Python, and the efficiency of themore » underlying C++, C and Fortran numerical kernels. This paper covers recent, previously unpublished advances in the PyTrilinos package.« less

  5. Clinical Management of Patients with ASXL1 Mutations and Bohring-Opitz Syndrome, Emphasizing the Need for Wilms Tumor Surveillance

    PubMed Central

    Russell, Bianca; Johnston, Jennifer J; Biesecker, Leslie G.; Kramer, Nancy; Pickart, Angela; Rhead, William; Tan, Wen-Hann; Brownstein, Catherine A; Clarkson, L Kate; Dobson, Amy; Rosenberg, Avi Z; Schrier Vergano, Samantha A.; Helm, Benjamin M.; Harrison, Rachel E; Graham, John M

    2016-01-01

    Bohring-Opitz syndrome is a rare genetic condition characterized by distinctive facial features, variable microcephaly, hypertrichosis, nevus flammeus, severe myopia, unusual posture (flexion at the elbows with ulnar deviation, and flexion of the wrists and metacarpophalangeal joints), severe intellectual disability, and feeding issues. Nine patients with Bohring-Opitz syndrome have been identified as having a mutation in ASXL1. We report on eight previously unpublished patients with Bohring-Opitz syndrome caused by an apparent or confirmed de novo mutation in ASXL1. Of note, two patients developed bilateral Wilms tumors. Somatic mutations in ASXL1 are associated with myeloid malignancies, and these reports emphasize the need for Wilms tumor screening in patients with ASXL1 mutations. We discuss clinical management with a focus on their feeding issues, cyclic vomiting, respiratory infections, insomnia, and tumor predisposition. Many patients are noted to have distinctive personalities (interactive, happy, and curious) and rapid hair growth; features not previously reported. PMID:25921057

  6. Geology of the Palo Alto 30 x 60 minute quadrangle, California: A digital database

    USGS Publications Warehouse

    Brabb, Earl E.; Graymer, R.W.; Jones, David Lawrence

    1998-01-01

    This map database represents the integration of previously published and unpublished maps by several workers (see Sources of Data index map on Sheet 2 and the corresponding table below) and new geologic mapping and field checking by the authors with the previously published geologic map of San Mateo County (Brabb and Pampeyan, 1983) and Santa Cruz County (Brabb, 1989, Brabb and others, 1997), and various sources in a small part of Santa Clara County. These new data are released in digital form to provide an opportunity for regional planners, local, state, and federal agencies, teachers, consultants, and others interested in geologic data to have the new data long before a traditional paper map is published. The new data include a new depiction of Quaternary units in the San Francisco Bay plain emphasizing depositional environment, important new observations between the San Andreas and Pilarcitos faults, and a new interpretation of structural and stratigraphic relationships of rock packages (Assemblages).

  7. Seasonal Distribution and Historic Trends in Abundance of White Sharks, Carcharodon carcharias, in the Western North Atlantic Ocean

    PubMed Central

    Curtis, Tobey H.; McCandless, Camilla T.; Carlson, John K.; Skomal, Gregory B.; Kohler, Nancy E.; Natanson, Lisa J.; Burgess, George H.; Hoey, John J.; Pratt, Harold L.

    2014-01-01

    Despite recent advances in field research on white sharks (Carcharodon carcharias) in several regions around the world, opportunistic capture and sighting records remain the primary source of information on this species in the northwest Atlantic Ocean (NWA). Previous studies using limited datasets have suggested a precipitous decline in the abundance of white sharks from this region, but considerable uncertainty in these studies warrants additional investigation. This study builds upon previously published data combined with recent unpublished records and presents a synthesis of 649 confirmed white shark records from the NWA compiled over a 210-year period (1800-2010), resulting in the largest white shark dataset yet compiled from this region. These comprehensive records were used to update our understanding of their seasonal distribution, relative abundance trends, habitat use, and fisheries interactions. All life stages were present in continental shelf waters year-round, but median latitude of white shark occurrence varied seasonally. White sharks primarily occurred between Massachusetts and New Jersey during summer and off Florida during winter, with broad distribution along the coast during spring and fall. The majority of fishing gear interactions occurred with rod and reel, longline, and gillnet gears. Historic abundance trends from multiple sources support a significant decline in white shark abundance in the 1970s and 1980s, but there have been apparent increases in abundance since the 1990s when a variety of conservation measures were implemented. Though the white shark's inherent vulnerability to exploitation warrants continued protections, our results suggest a more optimistic outlook for the recovery of this iconic predator in the Atlantic. PMID:24918579

  8. Relations of Dispositions toward Ridicule and Histrionic Self-Presentation with Quantitative and Qualitative Humor Creation Abilities.

    PubMed

    Renner, Karl-Heinz; Manthey, Leonie

    2018-01-01

    Previous research has shown that humor and self-presentation are linked in several ways. With regard to individual differences, it turned out that gelotophilia (the joy of being laughed at) and katagelasticism (the joy of laughing at others) are substantially associated with the histrionic self-presentation style that is characterized by performing explicit As-If-behaviors (e.g., irony, parodying others) in everyday interactions. By contrast, gelotophobia (the fear of being laughed at) shows a negative correlation with histrionic self-presentation. In order to further contribute to the nomological network, we have explored whether the three dispositions toward ridicule and laughter as well as histrionic self-presentation are related to humor creation abilities. In doing so, we have assessed the four constructs in a study with 337 participants that also completed the Cartoon Punch line Production Test (CPPT, Köhler and Ruch, 1993, unpublished). In the CPPT, subjects were asked to generate as many funny punch lines as possible for six caption-removed cartoons. The created punch lines were then analyzed with regard to quantitative (e.g., number of punch lines) and qualitative (e.g., wittiness of the punch lines and overall wittiness of the person as evaluated by three independent raters) humor creation abilities. Results show that both gelotophilia and histrionic self-presentation were positively correlated with quantitative and qualitative humor creation abilities. By contrast, gelotophobia showed slightly negative and katagelasticism no associations with the assessed humor creation abilities. These findings especially apply to the subgroup of participants that created punch lines for each of the six cartoons and partly replicate and extend the results of a previous study by Ruch et al. (2009). Altogether, the results of our study show that individual differences in humor-related traits are associated with the quantity and quality of humorous punch lines. It is argued that behavior-related or performative humor creation tasks should be considered in addition to the CPPT in order to open up new avenues that can cross-fertilize research on individual differences in humor and self-presentation.

  9. Relations of Dispositions toward Ridicule and Histrionic Self-Presentation with Quantitative and Qualitative Humor Creation Abilities

    PubMed Central

    Renner, Karl-Heinz; Manthey, Leonie

    2018-01-01

    Previous research has shown that humor and self-presentation are linked in several ways. With regard to individual differences, it turned out that gelotophilia (the joy of being laughed at) and katagelasticism (the joy of laughing at others) are substantially associated with the histrionic self-presentation style that is characterized by performing explicit As-If-behaviors (e.g., irony, parodying others) in everyday interactions. By contrast, gelotophobia (the fear of being laughed at) shows a negative correlation with histrionic self-presentation. In order to further contribute to the nomological network, we have explored whether the three dispositions toward ridicule and laughter as well as histrionic self-presentation are related to humor creation abilities. In doing so, we have assessed the four constructs in a study with 337 participants that also completed the Cartoon Punch line Production Test (CPPT, Köhler and Ruch, 1993, unpublished). In the CPPT, subjects were asked to generate as many funny punch lines as possible for six caption-removed cartoons. The created punch lines were then analyzed with regard to quantitative (e.g., number of punch lines) and qualitative (e.g., wittiness of the punch lines and overall wittiness of the person as evaluated by three independent raters) humor creation abilities. Results show that both gelotophilia and histrionic self-presentation were positively correlated with quantitative and qualitative humor creation abilities. By contrast, gelotophobia showed slightly negative and katagelasticism no associations with the assessed humor creation abilities. These findings especially apply to the subgroup of participants that created punch lines for each of the six cartoons and partly replicate and extend the results of a previous study by Ruch et al. (2009). Altogether, the results of our study show that individual differences in humor-related traits are associated with the quantity and quality of humorous punch lines. It is argued that behavior-related or performative humor creation tasks should be considered in addition to the CPPT in order to open up new avenues that can cross-fertilize research on individual differences in humor and self-presentation. PMID:29487549

  10. Acquiring and disseminating unpublished economic and social development materials in Africa: The case of the National Institute of Development Research and Documentation University of Botswana

    NASA Technical Reports Server (NTRS)

    Kwafo-Akoto, Kate

    1994-01-01

    Generally in Africa, the identification and acquisition of both published and unpublished documents can be an extremely difficult task due, among other factors, to the unsatisfactory state of the publishing industry and the poor state of bibliographic control. This paper analyzes the various problems involved in the acquisition of documents in Africa and illustrates them with the author's personal experience as an acquisitions librarian working on an information project which necessitated travel to about 15 African countries.

  11. Palaeoclimate determination from cave calcite deposits

    NASA Astrophysics Data System (ADS)

    Gascoyne, M.

    Calcite deposits formed in limestone caves have been found to be an excellent repository of palaeoclimatic data for terrestrial environments. The very presence of a relict deposit indicates non-glacial conditions at the time of formation, and both 14C and uranium-series methods can be used to date the deposit and, hence, the age of these climatic conditions. Variations in 13C and 18O content of the calcite, in 2H and 18O content of fluid inclusions, in trace element concentrations and, more recently, in pollen assemblages trapped in the calcite, are all potentially available as synchronous palaeoclimatic indicators. Previous work has tended to concentrate mainly on abundance of deposits as a palaeoclimatic indicator for the last 300,000 years. This literature is briefly reviewed here, together with the theory and methods of analysis of the U-series and stable isotopic techniques. The combined use of U-series ages and 13C and 18O variations in cave calcites illustrates the potential for palaeoclimate determination. Previously unpublished results of stable isotopic variations in dated calcites from caves in northern England indicate the level of detail of stable isotopic variations and time resolution that can be obtained, and the complexity of interpretation that may arise. Tentative palaeoclimatic signals for the periods 90-125 ka and 170-300 ka are presented. More comprehensive studies are needed in future work, especially in view of the difficulty in obtaining suitable deposits and the ethics of cave deposits conservation.

  12. A Thousand Fly Genomes: An Expanded Drosophila Genome Nexus.

    PubMed

    Lack, Justin B; Lange, Jeremy D; Tang, Alison D; Corbett-Detig, Russell B; Pool, John E

    2016-12-01

    The Drosophila Genome Nexus is a population genomic resource that provides D. melanogaster genomes from multiple sources. To facilitate comparisons across data sets, genomes are aligned using a common reference alignment pipeline which involves two rounds of mapping. Regions of residual heterozygosity, identity-by-descent, and recent population admixture are annotated to enable data filtering based on the user's needs. Here, we present a significant expansion of the Drosophila Genome Nexus, which brings the current data object to a total of 1,121 wild-derived genomes. New additions include 305 previously unpublished genomes from inbred lines representing six population samples in Egypt, Ethiopia, France, and South Africa, along with another 193 genomes added from recently-published data sets. We also provide an aligned D. simulans genome to facilitate divergence comparisons. This improved resource will broaden the range of population genomic questions that can addressed from multi-population allele frequencies and haplotypes in this model species. The larger set of genomes will also enhance the discovery of functionally relevant natural variation that exists within and between populations. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  13. Structural characterization of arginine-vasopressin and lysine-vasopressin by Fourier- transform ion cyclotron resonance mass spectrometry and infrared multiphoton dissociation.

    PubMed

    Bianco, Giuliana; Battista, Fabio; Buchicchio, Alessandro; Amarena, Concetta G; Schmitt-Kopplin, Philippe; Guerrieri, Antonio

    2015-01-01

    Arginine-vasopressin (AVP) and lysine-vasopressin (LVP) were analyzed by reversed-phase liquid chromatography/mass spectrometry (LC-MS) using Fourier-transform ion cyclotron resonance (FT-ICR) mass spectrometry (MS) electrospray ionization (ESI) in the positive ion mode. LVP and AVP exhibited the protonated adduct [M+H](+) as the predominant ion at m/z 1056.43965 and at m/z 1084.44561, respectively. Infrared multiphoton dissociation (IRMPD), using a CO(2) laser source at a wavelength of 10.6 μm, was applied to protonated vasopressin molecules. The IRMPD mass spectra presented abundant mass fragments essential for a complete structural information. Several fragment ions, shared between two target molecules, are discussed in detail. Some previously unpublished fragments were identified unambiguously utilizing the high resolution and accurate mass information provided by the FT-ICR mass spectrometer. The opening of the disulfide loop and the cleavage of the peptide bonds within the ring were observed even under low-energy fragmentation conditions. Coupling the high-performance FT-ICR mass spectrometer with IRMPD as a contemporary fragmentation technique proved to be very promising for the structural characterization of vasopressin.

  14. A literature review of blood concentrations of new psychoactive substances classified as phenethylamines, aminoindanes, arylalkylamines, arylcyclohexylamines, and indolalkylamines.

    PubMed

    Karinen, Ritva; Høiseth, Gudrun

    2017-07-01

    Interpretation of blood concentrations of new psychoactive substances (NPS) requires comparison of the results to previously published case reports; as only a few experimental studies for these substances exist. A large number of articles representing single or multiple cases have been published for a great number of substances, making a unified overview difficult. In this review we have collected all published blood concentrations from the NPS groups classified as phenethylamines, aminoindanes, arylalkylamines, arylcyclohexylamines, and indolalkylamines, and also included unpublished results for MPA, MXE, 4-FMA, 4-FA and 4-MA analyzed in our laboratory. In total, 71 publications on 35 different drugs were summarized. For most of the drugs, the total number of reported cases was very low (≤5). For some of the synthetic drugs, however, a higher number of blood concentrations are now available; especially for 5-IT (32 reported cases in total), MPA (31 reported cases in total) and MXE (36 reported cases in total), thus the published results are more substantial. The present compilation could be a helpful tool for forensic toxicologists when blood concentrations of NPS are assessed. Copyright © 2017. Published by Elsevier B.V.

  15. The Surtsey Magma Series.

    PubMed

    Schipper, C Ian; Jakobsson, Sveinn P; White, James D L; Michael Palin, J; Bush-Marcinowski, Tim

    2015-06-26

    The volcanic island of Surtsey (Vestmannaeyjar, Iceland) is the product of a 3.5-year-long eruption that began in November 1963. Observations of magma-water interaction during pyroclastic episodes made Surtsey the type example of shallow-to-emergent phreatomagmatic eruptions. Here, in part to mark the 50(th) anniversary of this canonical eruption, we present previously unpublished major-element whole-rock compositions, and new major and trace-element compositions of sideromelane glasses in tephra collected by observers and retrieved from the 1979 drill core. Compositions became progressively more primitive as the eruption progressed, with abrupt changes corresponding to shifts between the eruption's four edifices. Trace-element ratios indicate that the chemical variation is best explained by mixing of different proportions of depleted ridge-like basalt, with ponded, enriched alkalic basalt similar to that of Iceland's Eastern Volcanic Zone; however, the systematic offset of Surtsey compositions to lower Nb/Zr than other Vestmannaeyjar lavas indicates that these mixing end members are as-yet poorly contained by compositions in the literature. As the southwestern-most volcano in the Vestmannaeyjar, the geochemistry of the Surtsey Magma Series exemplifies processes occurring within ephemeral magma bodies on the extreme leading edge of a propagating off-axis rift in the vicinity of the Iceland plume.

  16. A high-precision chronological model for the decorated Upper Paleolithic cave of Chauvet-Pont d'Arc, Ardèche, France.

    PubMed

    Quiles, Anita; Valladas, Hélène; Bocherens, Hervé; Delqué-Količ, Emmanuelle; Kaltnecker, Evelyne; van der Plicht, Johannes; Delannoy, Jean-Jacques; Feruglio, Valérie; Fritz, Carole; Monney, Julien; Philippe, Michel; Tosello, Gilles; Clottes, Jean; Geneste, Jean-Michel

    2016-04-26

    Radiocarbon dates for the ancient drawings in the Chauvet-Pont d'Arc Cave revealed ages much older than expected. These early ages and nature of this Paleolithic art make this United Nations Educational, Scientific and Cultural Organization (UNESCO) site indisputably unique. A large, multidisciplinary dating program has recently mapped the anthropological evolution associated with the cave. More than 350 dates (by (14)C, U-Th, TL and (36)Cl) were obtained over the last 15 y. They include 259 radiocarbon dates, mainly related to the rock art and human activity in the cave. We present here more than 80 previously unpublished dates. All of the dates were integrated into a high-precision Bayesian model based on archaeological evidence to securely reconstruct the complete history of the Chauvet-Pont d'Arc Cave on an absolute timescale. It shows that there were two distinct periods of human activity in the cave, one from 37 to 33,500 y ago, and the other from 31 to 28,000 y ago. Cave bears also took refuge in the cave until 33,000 y ago.

  17. A high-precision chronological model for the decorated Upper Paleolithic cave of Chauvet-Pont d’Arc, Ardèche, France

    PubMed Central

    Quiles, Anita; Valladas, Hélène; Bocherens, Hervé; Delqué-Količ, Emmanuelle; Kaltnecker, Evelyne; van der Plicht, Johannes; Delannoy, Jean-Jacques; Feruglio, Valérie; Fritz, Carole; Monney, Julien; Philippe, Michel; Tosello, Gilles; Clottes, Jean; Geneste, Jean-Michel

    2016-01-01

    Radiocarbon dates for the ancient drawings in the Chauvet-Pont d’Arc Cave revealed ages much older than expected. These early ages and nature of this Paleolithic art make this United Nations Educational, Scientific and Cultural Organization (UNESCO) site indisputably unique. A large, multidisciplinary dating program has recently mapped the anthropological evolution associated with the cave. More than 350 dates (by 14C, U-Th, TL and 36Cl) were obtained over the last 15 y. They include 259 radiocarbon dates, mainly related to the rock art and human activity in the cave. We present here more than 80 previously unpublished dates. All of the dates were integrated into a high-precision Bayesian model based on archaeological evidence to securely reconstruct the complete history of the Chauvet-Pont d’Arc Cave on an absolute timescale. It shows that there were two distinct periods of human activity in the cave, one from 37 to 33,500 y ago, and the other from 31 to 28,000 y ago. Cave bears also took refuge in the cave until 33,000 y ago. PMID:27071106

  18. Milgram's Obedience to Authority experiments: origins and early evolution.

    PubMed

    Russell, Nestar John Charles

    2011-03-01

    Stanley Milgram's Obedience to Authority experiments remain one of the most inspired contributions in the field of social psychology. Although Milgram undertook more than 20 experimental variations, his most (in)famous result was the first official trial run - the remote condition and its 65% completion rate. Drawing on many unpublished documents from Milgram's personal archive at Yale University, this article traces the historical origins and early evolution of the obedience experiments. Part 1 presents the previous experiences that led to Milgram's conception of his rudimentary research idea and then details the role of his intuition in its refinement. Part 2 traces the conversion of Milgram's evolving idea into a reality, paying particular attention to his application of the exploratory method of discovery during several pilot studies. Both parts illuminate Milgram's ad hoc introduction of various manipulative techniques and subtle tension-resolving refinements. The procedural adjustments continued until Milgram was confident that the first official experiment would produce a high completion rate, a result contrary to expectations of people's behaviour. Showing how Milgram conceived of, then arrived at, this first official result is important because the insights gained may help others to determine theoretically why so many participants completed this experiment. ©2010 The British Psychological Society.

  19. Auditory evoked potentials in patients with major depressive disorder measured by Emotiv system.

    PubMed

    Wang, Dongcui; Mo, Fongming; Zhang, Yangde; Yang, Chao; Liu, Jun; Chen, Zhencheng; Zhao, Jinfeng

    2015-01-01

    In a previous study (unpublished), Emotiv headset was validated for capturing event-related potentials (ERPs) from normal subjects. In the present follow-up study, the signal quality of Emotiv headset was tested by the accuracy rate of discriminating Major Depressive Disorder (MDD) patients from the normal subjects. ERPs of 22 MDD patients and 15 normal subjects were induced by an auditory oddball task and the amplitude of N1, N2 and P3 of ERP components were specifically analyzed. The features of ERPs were statistically investigated. It is found that Emotiv headset is capable of discriminating the abnormal N1, N2 and P3 components in MDD patients. Relief-F algorithm was applied to all features for feature selection. The selected features were then input to a linear discriminant analysis (LDA) classifier with leave-one-out cross-validation to characterize the ERP features of MDD. 127 possible combinations out of the selected 7 ERP features were classified using LDA. The best classification accuracy was achieved to be 89.66%. These results suggest that MDD patients are identifiable from normal subjects by ERPs measured by Emotiv headset.

  20. Publication Bias in Antipsychotic Trials: An Analysis of Efficacy Comparing the Published Literature to the US Food and Drug Administration Database

    PubMed Central

    Turner, Erick H.; Knoepflmacher, Daniel; Shapley, Lee

    2012-01-01

    Background Publication bias compromises the validity of evidence-based medicine, yet a growing body of research shows that this problem is widespread. Efficacy data from drug regulatory agencies, e.g., the US Food and Drug Administration (FDA), can serve as a benchmark or control against which data in journal articles can be checked. Thus one may determine whether publication bias is present and quantify the extent to which it inflates apparent drug efficacy. Methods and Findings FDA Drug Approval Packages for eight second-generation antipsychotics—aripiprazole, iloperidone, olanzapine, paliperidone, quetiapine, risperidone, risperidone long-acting injection (risperidone LAI), and ziprasidone—were used to identify a cohort of 24 FDA-registered premarketing trials. The results of these trials according to the FDA were compared with the results conveyed in corresponding journal articles. The relationship between study outcome and publication status was examined, and effect sizes derived from the two data sources were compared. Among the 24 FDA-registered trials, four (17%) were unpublished. Of these, three failed to show that the study drug had a statistical advantage over placebo, and one showed the study drug was statistically inferior to the active comparator. Among the 20 published trials, the five that were not positive, according to the FDA, showed some evidence of outcome reporting bias. However, the association between trial outcome and publication status did not reach statistical significance. Further, the apparent increase in the effect size point estimate due to publication bias was modest (8%) and not statistically significant. On the other hand, the effect size for unpublished trials (0.23, 95% confidence interval 0.07 to 0.39) was less than half that for the published trials (0.47, 95% confidence interval 0.40 to 0.54), a difference that was significant. Conclusions The magnitude of publication bias found for antipsychotics was less than that found previously for antidepressants, possibly because antipsychotics demonstrate superiority to placebo more consistently. Without increased access to regulatory agency data, publication bias will continue to blur distinctions between effective and ineffective drugs. Please see later in the article for the Editors' Summary PMID:22448149

  1. Reconstructing the history of holography

    NASA Astrophysics Data System (ADS)

    Johnston, Sean F.

    2003-05-01

    This paper discusses large-scale but gradual changes in the subject of holography that have only recently become readily observable. Presenting an analysis of publications in holography over the past half century, the paper illustrates and discusses the evolving shape of the subject. Over 40,000 international information sources have been recorded, including some 20,000 papers, 10,000 books, nearly as many of these and at least 500 exhibitions. This statistical and sociological approach is combined with the identification of specific factors - notably the role of individuals, conferences, proof-of-concept demonstrations and exhibitions - to suggest that the development of holography has been unusually contingent on a variety of intellectual and social influences. The paper situates these observations about holography and holographers in the context of a wider discussion about the styles, purposes and difficulties of historical writing on technological subjects. It further suggests that this ongoing process of both recording and reconstructing technological history can be aided by identification of sources sometimes overlooked or undervalued by practitioners: unpublished archival materials such as private file collections; business records; or undervalued by practitioners: unpublished archival material such as private file collections; business records; accounts of unsuccessful activities; and, by no means least, anecdotal accounts inter-linked between participants.

  2. Parsing Glucose Entry into the Brain: Novel Findings Obtained with Enzyme-Based Glucose Biosensors

    PubMed Central

    2015-01-01

    Extracellular levels of glucose in brain tissue reflect dynamic balance between its gradient-dependent entry from arterial blood and its use for cellular metabolism. In this work, we present several sets of previously published and unpublished data obtained by using enzyme-based glucose biosensors coupled with constant-potential high-speed amperometry in freely moving rats. First, we consider basic methodological issues related to the reliability of electrochemical measurements of extracellular glucose levels in rats under physiologically relevant conditions. Second, we present data on glucose responses induced in the nucleus accumbens (NAc) by salient environmental stimuli and discuss the relationships between local neuronal activation and rapid glucose entry into brain tissue. Third, by presenting data on changes in NAc glucose induced by intravenous and intragastric glucose delivery, we discuss other mechanisms of glucose entry into the extracellular domain following changes in glucose blood concentrations. Lastly, by showing the pattern of NAc glucose fluctuations during glucose-drinking behavior, we discuss the relationships between “active” and “passive” glucose entry to the brain, its connection to behavior-related metabolic activation, and the possible functional significance of these changes in behavioral regulation. These data provide solid experimental support for the “neuronal” hypothesis of neurovascular coupling, which postulates the critical role of neuronal activity in rapid regulation of vascular tone, local blood flow, and entry of glucose and oxygen to brain tissue to maintain active cellular metabolism. PMID:25490002

  3. The GMOD Drupal bioinformatic server framework.

    PubMed

    Papanicolaou, Alexie; Heckel, David G

    2010-12-15

    Next-generation sequencing technologies have led to the widespread use of -omic applications. As a result, there is now a pronounced bioinformatic bottleneck. The general model organism database (GMOD) tool kit (http://gmod.org) has produced a number of resources aimed at addressing this issue. It lacks, however, a robust online solution that can deploy heterogeneous data and software within a Web content management system (CMS). We present a bioinformatic framework for the Drupal CMS. It consists of three modules. First, GMOD-DBSF is an application programming interface module for the Drupal CMS that simplifies the programming of bioinformatic Drupal modules. Second, the Drupal Bioinformatic Software Bench (biosoftware_bench) allows for a rapid and secure deployment of bioinformatic software. An innovative graphical user interface (GUI) guides both use and administration of the software, including the secure provision of pre-publication datasets. Third, we present genes4all_experiment, which exemplifies how our work supports the wider research community. Given the infrastructure presented here, the Drupal CMS may become a powerful new tool set for bioinformaticians. The GMOD-DBSF base module is an expandable community resource that decreases development time of Drupal modules for bioinformatics. The biosoftware_bench module can already enhance biologists' ability to mine their own data. The genes4all_experiment module has already been responsible for archiving of more than 150 studies of RNAi from Lepidoptera, which were previously unpublished. Implemented in PHP and Perl. Freely available under the GNU Public License 2 or later from http://gmod-dbsf.googlecode.com.

  4. Assessment of Accumulation Processes at the Middle Pleistocene Site of Ambrona (Soria, Spain). Density and Orientation Patterns in Spatial Datasets Derived from Excavations Conducted from the 1960s to the Present

    PubMed Central

    Sánchez-Romero, Laura; Benito-Calvo, Alfonso; Pérez-González, Alfredo; Santonja, Manuel

    2016-01-01

    The Middle Pleistocene site of Ambrona (Soria, Spain) is a major reference for European Acheulean studies. The origin of the lithic and fauna accumulations at this site was first thought to be anthropogenic, but later studies showed that it was mainly natural. The first person to conduct excavations at the Ambrona site was the Marquis of Cerralbo, in 1914; other research groups followed in more recent times (the Howell & Freeman team and the Santonja & Pérez-González team). The digs yielded a great amount of information, but until now it had never been unified. In this paper, we compile all the available published and unpublished excavation documentation from the 1960s to the present. We use these maps and sections to present our spatial study of the LSM (Lower Stratigraphic Member) at the Ambrona site, combining stratigraphic criteria with GIS density and orientation analysis. This study enabled us to define the main concentrations of the LSM, providing an initial contribution to an assessment of their accumulation processes. Most of the concentrations preserved in the ancient shore area of the site display marked orientation patterns which coincide with the direction of the main water flows into the Ambrona wetland. However, random orientation patterns were observed in the central part of the site (Alpha concentration); they may be mostly preserved without undergoing transport processes, as previous taphonomic studies also confirm. PMID:28002424

  5. Long working hours and alcohol use: systematic review and meta-analysis of published studies and unpublished individual participant data

    PubMed Central

    Jokela, Markus; Nyberg, Solja T; Madsen, Ida E H; Lallukka, Tea; Ahola, Kirsi; Alfredsson, Lars; Batty, G David; Bjorner, Jakob B; Borritz, Marianne; Burr, Hermann; Casini, Annalisa; Clays, Els; De Bacquer, Dirk; Dragano, Nico; Erbel, Raimund; Ferrie, Jane E; Fransson, Eleonor I; Hamer, Mark; Heikkilä, Katriina; Jöckel, Karl-Heinz; Kittel, France; Knutsson, Anders; Koskenvuo, Markku; Ladwig, Karl-Heinz; Lunau, Thorsten; Nielsen, Martin L; Nordin, Maria; Oksanen, Tuula; Pejtersen, Jan H; Pentti, Jaana; Rugulies, Reiner; Salo, Paula; Schupp, Jürgen; Siegrist, Johannes; Singh-Manoux, Archana; Steptoe, Andrew; Suominen, Sakari B; Theorell, Töres; Vahtera, Jussi; Wagner, Gert G; Westerholm, Peter J M; Westerlund, Hugo; Kivimäki, Mika

    2015-01-01

    Objective To quantify the association between long working hours and alcohol use. Design Systematic review and meta-analysis of published studies and unpublished individual participant data. Data sources A systematic search of PubMed and Embase databases in April 2014 for published studies, supplemented with manual searches. Unpublished individual participant data were obtained from 27 additional studies. Review methods The search strategy was designed to retrieve cross sectional and prospective studies of the association between long working hours and alcohol use. Summary estimates were obtained with random effects meta-analysis. Sources of heterogeneity were examined with meta-regression. Results Cross sectional analysis was based on 61 studies representing 333 693 participants from 14 countries. Prospective analysis was based on 20 studies representing 100 602 participants from nine countries. The pooled maximum adjusted odds ratio for the association between long working hours and alcohol use was 1.11 (95% confidence interval 1.05 to 1.18) in the cross sectional analysis of published and unpublished data. Odds ratio of new onset risky alcohol use was 1.12 (1.04 to 1.20) in the analysis of prospective published and unpublished data. In the 18 studies with individual participant data it was possible to assess the European Union Working Time Directive, which recommends an upper limit of 48 hours a week. Odds ratios of new onset risky alcohol use for those working 49-54 hours and ≥55 hours a week were 1.13 (1.02 to 1.26; adjusted difference in incidence 0.8 percentage points) and 1.12 (1.01 to 1.25; adjusted difference in incidence 0.7 percentage points), respectively, compared with working standard 35-40 hours (incidence of new onset risky alcohol use 6.2%). There was no difference in these associations between men and women or by age or socioeconomic groups, geographical regions, sample type (population based v occupational cohort), prevalence of risky alcohol use in the cohort, or sample attrition rate. Conclusions Individuals whose working hours exceed standard recommendations are more likely to increase their alcohol use to levels that pose a health risk. PMID:25587065

  6. Long working hours and alcohol use: systematic review and meta-analysis of published studies and unpublished individual participant data.

    PubMed

    Virtanen, Marianna; Jokela, Markus; Nyberg, Solja T; Madsen, Ida E H; Lallukka, Tea; Ahola, Kirsi; Alfredsson, Lars; Batty, G David; Bjorner, Jakob B; Borritz, Marianne; Burr, Hermann; Casini, Annalisa; Clays, Els; De Bacquer, Dirk; Dragano, Nico; Erbel, Raimund; Ferrie, Jane E; Fransson, Eleonor I; Hamer, Mark; Heikkilä, Katriina; Jöckel, Karl-Heinz; Kittel, France; Knutsson, Anders; Koskenvuo, Markku; Ladwig, Karl-Heinz; Lunau, Thorsten; Nielsen, Martin L; Nordin, Maria; Oksanen, Tuula; Pejtersen, Jan H; Pentti, Jaana; Rugulies, Reiner; Salo, Paula; Schupp, Jürgen; Siegrist, Johannes; Singh-Manoux, Archana; Steptoe, Andrew; Suominen, Sakari B; Theorell, Töres; Vahtera, Jussi; Wagner, Gert G; Westerholm, Peter J M; Westerlund, Hugo; Kivimäki, Mika

    2015-01-13

    To quantify the association between long working hours and alcohol use. Systematic review and meta-analysis of published studies and unpublished individual participant data. A systematic search of PubMed and Embase databases in April 2014 for published studies, supplemented with manual searches. Unpublished individual participant data were obtained from 27 additional studies. The search strategy was designed to retrieve cross sectional and prospective studies of the association between long working hours and alcohol use. Summary estimates were obtained with random effects meta-analysis. Sources of heterogeneity were examined with meta-regression. Cross sectional analysis was based on 61 studies representing 333,693 participants from 14 countries. Prospective analysis was based on 20 studies representing 100,602 participants from nine countries. The pooled maximum adjusted odds ratio for the association between long working hours and alcohol use was 1.11 (95% confidence interval 1.05 to 1.18) in the cross sectional analysis of published and unpublished data. Odds ratio of new onset risky alcohol use was 1.12 (1.04 to 1.20) in the analysis of prospective published and unpublished data. In the 18 studies with individual participant data it was possible to assess the European Union Working Time Directive, which recommends an upper limit of 48 hours a week. Odds ratios of new onset risky alcohol use for those working 49-54 hours and ≥ 55 hours a week were 1.13 (1.02 to 1.26; adjusted difference in incidence 0.8 percentage points) and 1.12 (1.01 to 1.25; adjusted difference in incidence 0.7 percentage points), respectively, compared with working standard 35-40 hours (incidence of new onset risky alcohol use 6.2%). There was no difference in these associations between men and women or by age or socioeconomic groups, geographical regions, sample type (population based v occupational cohort), prevalence of risky alcohol use in the cohort, or sample attrition rate. Individuals whose working hours exceed standard recommendations are more likely to increase their alcohol use to levels that pose a health risk. © Virtanen et al 2015.

  7. Original footage of the Chilean miners with manganism published in Neurology in 1967.

    PubMed

    Miranda, Marcelo; Bustamante, M Leonor; Mena, Francisco; Lees, Andrew

    2015-12-15

    Manganism has captured the imagination of neurologists for more than a century because of its similarities to Parkinson disease and its indirect but seminal role in the "l-dopa miracle." We present unpublished footage of the original case series reported in Neurology® in 1967 by Mena and Cotzias depicting the typical neurologic signs of manganism in 4 Chilean miners and their response to high doses of l-dopa. © 2015 American Academy of Neurology.

  8. Wind-Tunnel Investigation of the Low-Speed Static Stability and Control Characteristics of a Model of the Bell MX-776 (RASCAL) in Combined Angle of Attack and Sideslip

    NASA Technical Reports Server (NTRS)

    Letko, William

    1949-01-01

    An investigation has been made in the Langley stability tunnel to determine the low-speed static stability and control characteristics of a model of the Bell MX-776. The results show the model to be longitudinally unstable in the angle-of-attack range around zero angle of attack and to become stable at moderate angles of attack. The results of the present investigation agree reasonably well with results obtained in other facilities at low speed. The present pitching-moment results at low Mach numbers also agree reasonably well with unpublished results of tests of the model at supersonic Mach numbers (up to Mach number 1.86). Unpublished results at moderate and high subsonic speeds, however, indicate considerably greater instability at low angles of attack than is indicated by low-speed results. The results of the present tests also showed that the pitching-moment coefficients for angles of attack up to 12deg remained fairly constant with sideslip angle up to 12deg. The elevators tested produced relatively large pitching moments at zero angle of attack but, as the angle of attack was increased, the elevator effectiveness decreased. The rate of decrease of elevator effectiveness with angle of attack was less for 8deg than for 20deg elevator deflection. Therefore although 8deg deflection caused an appreciable change in longitudinal trim angle and trim lift coefficient a deflection of 20deg caused only a small additional increase in trim angle and trim lift coefficient.

  9. Long working hours and depressive symptoms: systematic review and meta-analysis of published studies and unpublished individual participant data.

    PubMed

    Virtanen, Marianna; Jokela, Markus; Madsen, Ida Eh; Magnusson Hanson, Linda L; Lallukka, Tea; Nyberg, Solja T; Alfredsson, Lars; Batty, G David; Bjorner, Jakob B; Borritz, Marianne; Burr, Hermann; Dragano, Nico; Erbel, Raimund; Ferrie, Jane E; Heikkilä, Katriina; Knutsson, Anders; Koskenvuo, Markku; Lahelma, Eero; Nielsen, Martin L; Oksanen, Tuula; Pejtersen, Jan H; Pentti, Jaana; Rahkonen, Ossi; Rugulies, Reiner; Salo, Paula; Schupp, Jürgen; Shipley, Martin J; Siegrist, Johannes; Singh-Manoux, Archana; Suominen, Sakari B; Theorell, Töres; Vahtera, Jussi; Wagner, Gert G; Wang, Jian Li; Yiengprugsawan, Vasoontara; Westerlund, Hugo; Kivimäki, Mika

    2018-05-01

    Objectives This systematic review and meta-analysis combined published study-level data and unpublished individual-participant data with the aim of quantifying the relation between long working hours and the onset of depressive symptoms. Methods We searched PubMed and Embase for published prospective cohort studies and included available cohorts with unpublished individual-participant data. We used a random-effects meta-analysis to calculate summary estimates across studies. Results We identified ten published cohort studies and included unpublished individual-participant data from 18 studies. In the majority of cohorts, long working hours was defined as working ≥55 hours per week. In multivariable-adjusted meta-analyses of 189 729 participants from 35 countries [96 275 men, 93 454 women, follow-up ranging from 1-5 years, 21 747 new-onset cases), there was an overall association of 1.14 (95% confidence interval (CI) 1.03-1.25] between long working hours and the onset of depressive symptoms, with significant evidence of heterogeneity (I 2 =45.1%, P=0.004). A moderate association between working hours and depressive symptoms was found in Asian countries (1.50, 95% CI 1.13-2.01), a weaker association in Europe (1.11, 95% CI 1.00-1.22), and no association in North America (0.97, 95% CI 0.70-1.34) or Australia (0.95, 95% CI 0.70-1.29). Differences by other characteristics were small. Conclusions This observational evidence suggests a moderate association between long working hours and onset of depressive symptoms in Asia and a small association in Europe.

  10. Preserving, Enhancing, and Continuing the Scientific Legacy of the Apollo Sample Suite

    NASA Astrophysics Data System (ADS)

    Zeigler, R. A.; Evans, C. A.; Lehnert, K.; Cai, Y.; Todd, N. S.

    2016-12-01

    From 1969 to 1972, Apollo astronauts collected 382 kg of rocks, soils, and core samples from six geologically diverse locations on the Moon. In the nearly 50 years since the samples were collected, over 3000 different studies have been conducted using the nearly 2200 different Apollo samples. Despite the maturity of the sample collection, many new studies of lunar samples are undertaken each year, with an average of >55 requests and >600 distinct subsamples allocated annually over the past five years. The Apollo samples are a finite resource, however. Although new studies are encouraged, it is important that new studies do not duplicate previous studies, and where possible, leverage previous results to inform and enhance the current studies. This helps to preserve the samples and scientific funding, both of which are precious resources. We have initiated several new efforts to rescue some of the early analyses from these samples, including unpublished analytical data. We are actively scanning NASA documentation in paper form that is related to the Apollo missions and sample processing, and we are collaborating with IEDA to establish a geochemical data base called MoonDB. To populate this database, we are actively working with about a dozen prominent lunar PIs to organize and transcribe years of both published and unpublished data, making it available to all researchers. This effort will also take advantage of new online analytical tools like PetDB. There have already been tangible results from the MoonDB data rescue effort. A pilot project involving the rescue of geochemical data of John Delano on Apollo pyroclastic glasses has already been referenced in multiple Apollo sample requests, and in fact, the compiled data was used as part of one of the new studies. Similarly, scanned sample handling reports have been utilized to find previously analyzed samples that were appropriate to fulfill new sample requests. We have also begun to image the Apollo samples using (1) micro-CT scanning to document the interior structure of samples, and (2) comprehensive high resolution photography of samples, enabling high resolution 3D reconstructions of the samples. Both efforts will provide comprehensive access to these samples and allow for more targeted requests, and thus better curation of the samples for decades to come.

  11. Preserving, Enhancing, and Continuing the Scientific Legacy of the Apollo Sample Suite

    NASA Technical Reports Server (NTRS)

    Zeigler, Ryan; Evans, Cindy; Cai, Yue; Lehnert, Kerstin; Todd, Nancy; Blumenfeld, Erika

    2016-01-01

    From 1969 to 1972, Apollo astronauts collected 382 kg of rocks, soils, and core samples from six geologically diverse locations on the Moon. In the nearly 50 years since the samples were collected, over 3000 different studies have been conducted using the nearly 2200 different Apollo samples. Despite the maturity of the sample collection, many new studies of lunar samples are undertaken each year, with an average of more than 55 requests and more than 600 distinct subsamples allocated annually over the past five years. The Apollo samples are a finite resource, however. Although new studies are encouraged, it is important that new studies do not duplicate previous studies, and where possible, leverage previous results to inform and enhance the current studies. This helps to preserve the samples and scientific funding, both of which are precious resources. We have initiated several new efforts to rescue some of the early analyses from these samples, including unpublished analytical data. We are actively scanning NASA documentation in paper form that is related to the Apollo missions and sample processing, and we are collaborating with IEDA to establish a geochemical data base called MoonDB. To populate this database, we are actively working with about a dozen prominent lunar PIs to organize and transcribe years of both published and unpublished data, making it available to all researchers. This effort will also take advantage of new online analytical tools like PetDB. There have already been tangible results from the MoonDB data rescue effort. A pilot project involving the rescue of geochemical data of John Delano on Apollo pyroclastic glasses has already been referenced in multiple Apollo sample requests, and in fact, the compiled data was used as part of one of the new studies. Similarly, scanned sample handling reports have been utilized to find previously analyzed samples that were appropriate to fulfill new sample requests. We have also begun to image the Apollo samples using (1) micro-CT scanning to document the interior structure of samples, and (2) comprehensive high resolution photography of samples, enabling high resolution 3D reconstructions of the samples. Both efforts will provide comprehensive access to these samples and allow for more targeted requests, and thus better curation of the samples for decades to come.

  12. Radiometric age determinations on Pliocene/Pleistocene formations in the lower Omo basin, Ethiopia

    USGS Publications Warehouse

    Brown, F.H.; Lajoie, K.R.

    1971-01-01

    THE potassium-argon ages presented here were obtained during 1966 to 1969 in order to provide an absolute time scale for the stratigraphic work by the international Omo Research Expedition in the Pliocene/Pleistocene formations (unpublished work of F. H. B., J. de Heinzelin and F. C. Howell) in south-west Ethiopia. Although some of these dates are not new1-3, most of the analytical procedures and data have not been presented. We also present a list of fossil localities recorded by the University of Chicago contingent of the expedition within the Shungura Formation. Preliminary descriptions of the Hominidae have been published already3,4. ?? 1971 Nature Publishing Group.

  13. 8-Way Randomized Controlled Trial of Doxylamine, Pyridoxine and Dicyclomine for Nausea and Vomiting during Pregnancy: Restoration of Unpublished Information.

    PubMed

    Zhang, Rujun; Persaud, Navindra

    2017-01-01

    We report information about an unpublished 1970s study ("8-way" Bendectin Study) that aimed to evaluate the relative therapeutic efficacy of doxylamine, pyridoxine, and dicyclomine in the management of nausea and vomiting during pregnancy. We are publishing the trial's findings according to the restoring invisible and abandoned trials (RIAT) initiative because the trial was never published. Double blinded, multi-centred, randomized placebo-controlled study. 14 clinics in the United States. 2308 patients in the first 12 weeks of pregnancy with complaints of nausea or vomiting were enrolled. Each patient was randomized to one of eight arms: placebo, doxylamine/pyridoxine/dicylcomine, doxylamine/pyridoxine, dicylomine/pyridoxine, doxylamine, dicyclomine/pyridoxine, pyridoxine and dicyclomine. Each patient was instructed to take 2 tablets at bedtime and 1 additional tablet in the afternoon or morning if needed, for 7 nights. Reported outcomes included the number of hours of nausea reported by patients, the frequency of vomiting reported by patients and the overall efficacy of medication as judged by physicians. Data from 1599 (69% of those randomized) participants were analyzed. Based on the available summary data of physician evaluation of symptoms and ignoring missing data and data integrity issues, the proportion of participants who were "evaluated moderate or excellent" was greater in each of the seven active treatment groups when compared with placebo (57%): doxylamine/pyridoxine/dicylcomine (14% absolute difference versus placebo; 95% CI: 4 to 24), doxylamine/pyridoxine (21; 95% CI 11 to 30), dicylomine/pyridoxine (21; 95% CI 11 to 30), doxylamine (20; 95% CI 10 to 29), dicyclomine/pyridoxine (4; 95% CI -6 to 14), pyridoxine (9; 95% CI -1 to 19) and dicyclomine (4; 95% CI -6 to 14). Based on incomplete information, the most common adverse events were apparently drowsiness and fatigue. There is a high risk of bias in these previously unpublished results given the high attrition rate in a 7 day trial, the lack of prespecified outcomes or analyses, and the exclusion of some data because of questionable data integrity. The available information about this "8-way Bendectin" trial indicates it should not be used to support the efficacy of doxylamine, pyridoxine or dicyclomine for the treatment of nausea and vomiting during pregnancy because of a high risk of bias. Not registered.

  14. Analysis of full-text publication and publishing predictors of abstracts presented at an Italian public health meeting (2005-2007).

    PubMed

    Castaldi, S; Giacometti, M; Toigo, W; Bert, F; Siliquini, R

    2015-09-29

    In Public Health, a thorough review of abstract quality evaluations and the publication history of studies presented at scientific meetings has never been conducted. To analyse the long-term outcome of quality abstracts submitted to conferences of Italian Society of Hygiene and Public Health (SItI) from 2005 to 2007, we conducted a second analysis of previously published material aiming to estimate full-text publication rate of high quality abstract presented at Italian public health meetings, and to identify predictors of full-text publication. The search was undertaken through scientific databases and search engines and through the web sites of the major Italian journals of Public Health. For each publication confirmed as a full text paper, the journal name, impact factor, year of publication, gender of the first author, type of study design, characteristics of the results and sample size were collected. The overall publication rate of the abstracts presented is 23.5%; most of the papers were published in Public Health journals (average impact factor: 3.007). Non universitary affiliation had resulted in a lower probability of publication, while some of the Conference topics had predisposed the studies to an increased likelihood of publication as well as poster form presentation. The method presented in this study provides a good framework for the evaluation of the scientific evidence. The findings achieved should be taken into consideration by the Scientific Societies during the contributions selection phase, with the aim of achieving a continuous improvement of work quality. In the future, it would be interesting to survey the abstract authors to identify reasons for unpublished data.

  15. Evaluation of the photochemical reflectance index in AVIRIS imagery

    NASA Technical Reports Server (NTRS)

    Gamon, John A.; Roberts, Dar A.; Green, Robert O.

    1995-01-01

    In this paper, we evaluate the potential for extracting the 'photochemical reflectance index' (PRI; previously called the 'physiological reflectance index') from AVIRIS data. This index, which is derived from narrow-band reflectance at 531 and 570 nm, has proven to be a useful indicator of photosynthetic function at the leaf and canopy scales. At the leaf level, PRI varies with photosynthetic capacity, radiation-use efficiency, and vegetation type (unpublished data). This finding is consistent with the hypothesis that vegetation types exhibiting chronically reduced photosynthesis during periods of stress (e.g. drought-tolerant evergreens) invest proportionally more in photoprotective processes than vegetation with high photosynthetic capacity (e.g. crops or deciduous perennials). Vertical transects in tropical and boreal forest canopies have indicated declines in PRI associated with downregulation of photosynthesis at the canopy tops under sunny, dry midday conditions (unpublished data). This reduced PRI in upper canopy levels provides a further basis for examining this signal with the 'view from above' afforded by aircraft overflights. Although many factors could confound interpretation of a subtle physiological signal at the landscape scale, we conducted a preliminary examination of PRI extracted from existing, AVIRIS imagery of Stanford University's Jasper Ridge Biological Preserve obtained on the June 2nd, 1992, overflight. The goal was to use the hyperspectral capabilities of AVIRIS to evaluate the potential of this index for obtaining useful physiological data at the landscape scale. The expectation based on leaf- and canopy-level studies was that regions containing vegetation of reduced photosynthetic capacity (e.g. chaparral or evergreen woodland) would exhibit lower PRI values than regions of high capacity (e.g. deciduous woodland).

  16. Women and Chemistry in Regency England: New Light on the Marcet Circle.

    PubMed

    Leigh, G Jeffery; Rocke, Alan J

    2016-02-01

    Jane Marcet's Conversations on Chemistry (first edition, 1806) was possibly the best-selling English-language chemistry book of the first half of the nineteenth century. Recent scholarship has explored the degree to which her husband assisted in the writing of the book, without diminishing the high merits of the author. Previously unpublished correspondence, some of which appears here for the first time, casts new light on the social and professional circle of Jane and Alexander Marcet, including its influence on Jane's book. One of the members of that circle was a hitherto unrecognised but highly capable young female chemist, Frederica Sebright. The story told here underlines the tensions in elite circles in early nineteenth-century England between broad-minded acceptance and patronising limitations for women in science.

  17. How to Manage Rejected Scientific Papers? UNAIS as Final Solution.

    PubMed

    Diana, Alessandro

    2012-01-01

    Before publication, biomedical papers might undergo a very complex process, from journal selection, authors' motivations for submissions, modifications, and final publication or refusal. UNAIS (Unpublished Articles In Science) is an online repository in which authors can publish previously rejected scientific articles or articles that have never been submitted for publication. At UNAIS, authors can also publish the reasons behind the refusals to publication. UNAIS is more than an e-journal: it is a scientific drop box in which scientists can find indicative and negative results, as well as ideas that can inspire others. UNAIS's goal is also to help students and scientists who want to learn how to write scientific articles. UNAIS' aim is to exchange and promote knowledge. Have a look on www.unais.net.

  18. Ancient Maritime Fish-Traps of Brittany (France): A Reappraisal of the Relationship Between Human and Coastal Environment During the Holocene

    NASA Astrophysics Data System (ADS)

    Langouët, Loïc; Daire, Marie-Yvane

    2009-12-01

    The present-day maritime landscape of Western France forms the geographical framework for a recent research project dedicated to the archaeological study of ancient fish-traps, combining regional-scale and site-scale investigations. Based on the compilation and exploitation of a large unpublished dataset including more than 550 sites, a preliminary synthetic study allows us to present some examples of synchronic and thematic approaches, and propose a morphological classification of the weirs. These encouraging first results open up new perspectives on fish-trap chronology closely linked to wider studies on Holocene sea-level changes.

  19. Comparison of published and unpublished phase I clinical cancer trials: an analysis of the CliniclTrials.gov database.

    PubMed

    Shepshelovich, D; Goldvaser, H; Wang, L; Abdul Razak, A R

    2017-12-13

    Introduction The role of phase I cancer trials is constantly evolving and they are increasingly being used in 'go/no' decisions in drug development. As a result, there is a growing need to ensure trials are published when completed. There are limited data on the publication rate and the factors associated with publication in phase I trials. Methods The ClinicalTrials.gov database was searched for completed adult phase I cancer trials with reported results. PubMed was searched for matching publications published prior to April 1, 2017. Logistic regression was used to identify factors associated with unpublished trials. Linear regression was used to explore factors associated with time lag from study database lock to publication for published trials. Results The study cohort included 319 trials. 95 (30%) trials had no matching publication. Thirty (9%) trials were not published in abstract form as well. On multivariable analysis, the most significant factor associated with unpublished trials was industry funding (odds ratio 3.3, 95% confidence interval 1.7-6.6, p=0.019). For published trials, time lag between database lock and publication was longer by 10.9 months (standard error 3.6, p<0.001) for industry funded trials compared with medical center funded trials. Conclusions Timely publishing of early cancer clinical trials results remains unsatisfactory. Industry funded phase I cancer trials were more likely to remain unpublished, and were associated with a longer time lag from database lock to publication. Policies that promote transparency and data sharing in clinical trial research might improve accountability among industry and investigators and improve timely results publication.

  20. Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis.

    PubMed

    Kerkhof, H J M; Doherty, M; Arden, N K; Abramson, S B; Attur, M; Bos, S D; Cooper, C; Dennison, E M; Doherty, S A; Evangelou, E; Hart, D J; Hofman, A; Javaid, K; Kerna, I; Kisand, K; Kloppenburg, M; Krasnokutsky, S; Maciewicz, R A; Meulenbelt, I; Muir, K R; Rivadeneira, F; Samuels, J; Sezgin, M; Slagboom, E; Smith, A J P; Spector, T D; Tamm, A; Tamm, A; Uitterlinden, A G; Wheeler, M; Zhai, G; Zhang, W; van Meurs, J B J; Valdes, A M

    2011-03-01

    To clarify the role of common genetic variation in the Interleukin-1β (IL1B) and Interleukin-1R antagonist (IL1RN) genes on risk of knee and hip osteoarthritis (OA) and severity of knee OA by means of large-scale meta-analyses. We searched PubMed for articles assessing the role of IL1B and IL1RN polymorphisms/haplotypes on the risk of hip and/or knee OA. Novel data were included from eight unpublished studies. Meta-analyses were performed using fixed- and random-effects models with a total of 3595 hip OA and 5013 knee OA cases, and 6559 and 9132 controls respectively. The role of ILRN haplotypes on radiographic severity of knee OA was tested in 1918 cases with Kellgren-Lawrence (K/L) 1 or 2 compared to 199 cases with K/L 3 or 4. The meta-analysis of six published studies retrieved from the literature search and eight unpublished studies showed no evidence of association between common genetic variation in the IL1B or IL1RN genes and risk of hip OA or knee OA (P>0.05 for rs16944, rs1143634, rs419598 and haplotype C-G-C (rs1143634, rs16944 and rs419598) previously implicated in risk of hip OA). The C-T-A haplotype formed by rs419598, rs315952 and rs9005, previously implicated in radiographic severity of knee OA, was associated with reduced severity of knee OA (odds ratio (OR)=0.71 95%CI 0.56-0.91; P=0.006, I(2)=74%), and achieved borderline statistical significance in a random-effects model (OR=0.61 95%CI 0.35-1.06 P=0.08). Common genetic variation in the Interleukin-1 region is not associated with prevalence of hip or knee OA but our data suggest that IL1RN might have a role in severity of knee OA. Copyright © 2010 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

  1. Analysis of time dependent phenomena observed with the LPSP OSO-8 instrument

    NASA Technical Reports Server (NTRS)

    Leibacher, J. W.

    1979-01-01

    The dynamics of the solar photosphere and chromosphere are studied. Observations obtained by the Laboratorie de Physique Stellaire et Planetaire's (LPSP) ultraviolet spectrometer onboard the OSO-8 spacecraft are analyzed, and dynamic models of the chromosphere and the emitted resonance line spectrum are calculated. Some of the unpublished data analysis and theoretical modeling which are being prepared for publication are discussed. A discussion of the state of the theory of velocity fields in the solar atmosphere is also presented. An invited review presented at the OSO-8 Workshop on the topic of oscillatory motions in the quiet sun is included. The results of the OSO-8 data analysis prepared in close collaboration with LPSP scientists are presented. Material for two articles is also presented.

  2. Fair Use and Unpublished Works. Joint Hearing on S. 2370 and H.R. 4263, Bills To Amend Section 107 of Title 17, United States Code...before the Subcommittee on Patents, Copyrights, and Trademarks of the Senate Committee on the Judiciary and the Subcommittee on Courts, Intellectual Property, and the Administration of Justice of the House Committee on the Judiciary.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Committee on the Judiciary.

    This hearing was called to consider two bills that would amend the section of the United States Code relating to fair use, to clarify that such section applies to both published and unpublished copyrighted works. Recent judicial developments are reviewed which suggest that the fair use doctrine does not apply to the subsequent uses of unpublished…

  3. Validation of the regional climate model MAR over the CORDEX Africa domain and comparison with other regional models using unpublished data set

    NASA Astrophysics Data System (ADS)

    Prignon, Maxime; Agosta, Cécile; Kittel, Christoph; Fettweis, Xavier; Michel, Erpicum

    2016-04-01

    In the framework of the CORDEX project, we have applied the regional model MAR over the Africa domain at a resolution of 50 km. ERA-Interim and NCEP-NCAR reanalysis have been used as 6 hourly forcing at the MAR boundaries over 1950-2015. While MAR was already been validated over the West Africa, it is the first time that MAR simulations are carried out at the scale of the whole continent. Unpublished daily measurements, covering the Sahel and more areas up South, with a large set of variables, are used as validation of MAR, other CORDEX-Africa RCMs and both reanalyses. Comparisons with the CRU and the ECA&D databases are also performed. The unpublished daily data set covers the period 1884-2006 and comes from 1460 stations. The measured variables are wind, evapotranspiration, relative humidity, insolation, rain, surface pressure, temperature, vapour pressure and visibility. It covers 23 countries: Algeria, Benin, Burkina, Canary Islands, Cap Verde, Central Africa, Chad, Congo, Ivory Coast, Gabon, Gambia, Ghana, Guinea, Guinea-Bissau, Mali, Mauritania, Morocco, Niger, Nigeria, Senegal, Sudan and Togo.

  4. Why Quark Rhymes with Pork

    NASA Astrophysics Data System (ADS)

    Mermin, N. David

    2016-03-01

    Part I. Reference Frame Columns, Physics Today, 1988-2009: 1. What's wrong with this Lagrangean? April 1988; 2. What's wrong with this library? August 1988; 3. What's wrong with these prizes? January 1989; 4. What's wrong with this pillow? April 1989; 5. What's wrong with this prose? May 1989; 6. What's wrong with these equations? October 1989; 7. What's wrong with these elements of reality? June 1990; 8. What's wrong with these reviews? August 1990; 9. What's wrong with those epochs? November 1990; 10. Publishing in computopia, May 1991; 11. What's wrong with those grants, June 1991; 12. What's wrong in computopia, April 1992; 13. What's wrong with those talks? November 1992; 14. Two lectures on the wave-particle duality, January 1993; 15. A quarrel we can settle, December 1993; 16. What's wrong with this temptation, June 1994; 17. What's wrong with this sustaining myth, March 1996; 18. The golemization of relativity, April 1996; 19. Diary of a Nobel guest, March 1997; 20. What's wrong with this reading, October 1997; 21. How not to create tigers, August 1999; 22. What's wrong with this elegance? March 2000; 23. The contemplation of quantum computation, July 2000; 24. What's wrong with these questions? February 2001; 25. What's wrong with this quantum world? February 2004; 26. Could Feynman have said this? May 2004; 27. My life with Einstein, December 2005; 28. What has quantum mechanics to do with factoring? April 2007; 29. Some curious facts about quantum factoring, October 2007; 30. What's bad about this habit, May 2009; Part II. Shedding Bad Habits: 31. Fixing the shifty split, Physics Today, July 2012; 32. What I think about Now, Physics Today, March 2014; 33. Why QBism is not the Copenhagen interpretation, lecture, Vienna, June 2014; Part III. More from Professor Mozart: 34. What's wrong with this book? Unpublished, 1992; 35. What's wrong with these stanzas? Physics Today, July 2007; Part IV. More to be said: 36. The complete diary of a Nobel guest, unpublished, 1996; 37. Elegance in physics, unpublished lecture, Minneapolis, 1999; 38. Questions for 2105, unpublished lecture, Zurich, 2005; Part V. Some People I've Known: 39. My life with Fisher, lecture, Rutgers University, 2001; 40. My life with Kohn, 2003, updated 2013; 41. My life with Wilson, lecture, Cornell University, 2014; 42. My life with Peierls, unpublished lecture, Santa Barbara, 1997; Part VI. Summing It Up: 43. Writing physics, lecture, Cornell University, 1999.

  5. Systematic review finds that study data not published in full text articles have unclear impact on meta-analyses results in medical research.

    PubMed

    Schmucker, Christine M; Blümle, Anette; Schell, Lisa K; Schwarzer, Guido; Oeller, Patrick; Cabrera, Laura; von Elm, Erik; Briel, Matthias; Meerpohl, Joerg J

    2017-01-01

    A meta-analysis as part of a systematic review aims to provide a thorough, comprehensive and unbiased statistical summary of data from the literature. However, relevant study results could be missing from a meta-analysis because of selective publication and inadequate dissemination. If missing outcome data differ systematically from published ones, a meta-analysis will be biased with an inaccurate assessment of the intervention effect. As part of the EU-funded OPEN project (www.open-project.eu) we conducted a systematic review that assessed whether the inclusion of data that were not published at all and/or published only in the grey literature influences pooled effect estimates in meta-analyses and leads to different interpretation. Systematic review of published literature (methodological research projects). Four bibliographic databases were searched up to February 2016 without restriction of publication year or language. Methodological research projects were considered eligible for inclusion if they reviewed a cohort of meta-analyses which (i) compared pooled effect estimates of meta-analyses of health care interventions according to publication status of data or (ii) examined whether the inclusion of unpublished or grey literature data impacts the result of a meta-analysis. Seven methodological research projects including 187 meta-analyses comparing pooled treatment effect estimates according to different publication status were identified. Two research projects showed that published data showed larger pooled treatment effects in favour of the intervention than unpublished or grey literature data (Ratio of ORs 1.15, 95% CI 1.04-1.28 and 1.34, 95% CI 1.09-1.66). In the remaining research projects pooled effect estimates and/or overall findings were not significantly changed by the inclusion of unpublished and/or grey literature data. The precision of the pooled estimate was increased with narrower 95% confidence interval. Although we may anticipate that systematic reviews and meta-analyses not including unpublished or grey literature study results are likely to overestimate the treatment effects, current empirical research shows that this is only the case in a minority of reviews. Therefore, currently, a meta-analyst should particularly consider time, effort and costs when adding such data to their analysis. Future research is needed to identify which reviews may benefit most from including unpublished or grey data.

  6. Systematic review finds that study data not published in full text articles have unclear impact on meta-analyses results in medical research

    PubMed Central

    Blümle, Anette; Schell, Lisa K.; Schwarzer, Guido; Oeller, Patrick; Cabrera, Laura; von Elm, Erik; Briel, Matthias; Meerpohl, Joerg J.

    2017-01-01

    Background A meta-analysis as part of a systematic review aims to provide a thorough, comprehensive and unbiased statistical summary of data from the literature. However, relevant study results could be missing from a meta-analysis because of selective publication and inadequate dissemination. If missing outcome data differ systematically from published ones, a meta-analysis will be biased with an inaccurate assessment of the intervention effect. As part of the EU-funded OPEN project (www.open-project.eu) we conducted a systematic review that assessed whether the inclusion of data that were not published at all and/or published only in the grey literature influences pooled effect estimates in meta-analyses and leads to different interpretation. Methods and findings Systematic review of published literature (methodological research projects). Four bibliographic databases were searched up to February 2016 without restriction of publication year or language. Methodological research projects were considered eligible for inclusion if they reviewed a cohort of meta-analyses which (i) compared pooled effect estimates of meta-analyses of health care interventions according to publication status of data or (ii) examined whether the inclusion of unpublished or grey literature data impacts the result of a meta-analysis. Seven methodological research projects including 187 meta-analyses comparing pooled treatment effect estimates according to different publication status were identified. Two research projects showed that published data showed larger pooled treatment effects in favour of the intervention than unpublished or grey literature data (Ratio of ORs 1.15, 95% CI 1.04–1.28 and 1.34, 95% CI 1.09–1.66). In the remaining research projects pooled effect estimates and/or overall findings were not significantly changed by the inclusion of unpublished and/or grey literature data. The precision of the pooled estimate was increased with narrower 95% confidence interval. Conclusions Although we may anticipate that systematic reviews and meta-analyses not including unpublished or grey literature study results are likely to overestimate the treatment effects, current empirical research shows that this is only the case in a minority of reviews. Therefore, currently, a meta-analyst should particularly consider time, effort and costs when adding such data to their analysis. Future research is needed to identify which reviews may benefit most from including unpublished or grey data. PMID:28441452

  7. Out-migration and depopulation of the Russian North during the 1990s.

    PubMed

    Heleniak, T

    1999-01-01

    The large-scale out-migration from Russia's northern regions that has taken place over the course of the 1990s is analyzed. "The study is based on unpublished oblast-level migration data compiled by the Russian Government, field work by the author, as well as two extensive 1998 surveys of recent and potential migrants, respectively. Age, gender, and educational level of migrants are analyzed to determine the extent of change in Northern population structure attributable to migration. A concluding section presents Russian Government projections of the North's population to 2010." excerpt

  8. [Freud's abstract of "A contribution to the option of neurosis" (1913). Publication and commentary].

    PubMed

    May, Ulrike

    2011-01-01

    The text, which is published here for the first time, summarizes the paper Freud presented to the IPA congress in Munich. A short commentary highlights the circumstances under which the paper was written and the reasons why the abstract remained unpublished. It also sketches the historical significance of the paper in terms of the problem of the option of neurosis, in particular obsessional neurosis, of the development of Freud's sexual theory and of the relation of his views to those of Ernest Jones.

  9. Injuries among railroad trespassers--Georgia, 1990-1996.

    PubMed

    1999-07-02

    Railroad trespassers are persons on railroad property whose presence is prohibited or unlawful. Most trespassers are walking along or across railroad tracks. In 1997, fatalities to railroad trespassers became the leading cause of railroad-related deaths in the United States. In 1998, 513 persons were injured and 536 persons were killed while trespassing (Federal Railroad Administration, unpublished data, 1999). This report presents three incidents in which trespassers were injured or killed and summarizes a study of fatal and nonfatal injuries to railroad trespassers in Georgia from 1990 through 1996.

  10. The Einstein Dossiers: Science and Politics - Einstein's Berlin Period with an Appendix on Einstein's FBI File

    NASA Astrophysics Data System (ADS)

    Grundmann, Siegfried

    In 1919 the Prussian Ministry of Science, Arts and Culture opened a dossier on "Einstein's Theory of Relativity." It was rediscovered by the author in 1961 and is used in conjunction with numerous other subsequently identified 'Einstein' files as the basis of this fascinating book. In particular, the author carefully scrutinizes Einstein's FBI file from 1950-55 against mostly unpublished material from European including Soviet sources and presents hitherto unknown documentation on Einstein's alleged contacts with the German Communist Party and the Comintern.

  11. Generalized thickness of the confining bed overlying the Floridan Aquifer, Southwest Florida Water Management District

    USGS Publications Warehouse

    Buono, Anthony; Spechler, R.M.; Barr, G.L.; Wolansky, R.M.

    1979-01-01

    This map presents the thickness of the confining bed overlying the Floridan aquifer in the Southwest Florida Water Management District and adjacent areas. The bed separates the surficial aquifer from the underlying Floridan aquifer. Lithologic logs and information from quarries were used in conjunction with an unpublished map to compile this map at 1:250,000 scale. Units included in the confining bed are: clay, sandy clay and marl, undifferentiated with respect to age, the Hawthorn Formation, and the unconsolidated sections of the Tampa Limestone. (Kosco-USGS)

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    King, W. D.

    In order to appropriately model and predict the chemical integrity and performance of cementitious materials used for waste immobilization at the Savannah River Site (SRS), it is critical to understand the I-129 solubility and distribution within the tank farm. Iodine in radioactive waste and in environmental media is typically highly mobile and long lived. Iodine is ubiquitous in SRS tank waste and waste forms. The iodine is assumed to be soluble and present at low levels in Performance Assessments (PAs) for SRS Tank Farms, and is one of the dose drivers in the PAs for both the SRS Salt Disposalmore » Facility (SDF) and the H-Area Tank Farm (HTF). Analysis of tank waste samples is critical to understanding the Tank Farm iodine inventory and reducing disposal uncertainty. Higher than expected iodine levels have recently been observed in residual solids isolated from some SRS tanks prior to closure, indicating uncertainty regarding the chemical species involved. If the iodine inventory uncertainty is larger than anticipated, future work may be necessary to reduce the uncertainty. This memorandum satisfies a portion of the work scope identified in Task Plan SRNL-RP-2016-00651. A separate memorandum issued previously, reported historical unpublished I-129 data, a significant portion of which was below detectable analytical limits. This memorandum includes iodine and general chemical analysis results for six archived SRNL samples which were previously reported to have I-129 concentrations below detectable limits. Lower sample dilution factors were used for the current analyses in order to obtain concentrations above detection. The samples analyzed included surface and depth samples from SRS tanks 30, 32, and 39.« less

  13. The GMOD Drupal Bioinformatic Server Framework

    PubMed Central

    Papanicolaou, Alexie; Heckel, David G.

    2010-01-01

    Motivation: Next-generation sequencing technologies have led to the widespread use of -omic applications. As a result, there is now a pronounced bioinformatic bottleneck. The general model organism database (GMOD) tool kit (http://gmod.org) has produced a number of resources aimed at addressing this issue. It lacks, however, a robust online solution that can deploy heterogeneous data and software within a Web content management system (CMS). Results: We present a bioinformatic framework for the Drupal CMS. It consists of three modules. First, GMOD-DBSF is an application programming interface module for the Drupal CMS that simplifies the programming of bioinformatic Drupal modules. Second, the Drupal Bioinformatic Software Bench (biosoftware_bench) allows for a rapid and secure deployment of bioinformatic software. An innovative graphical user interface (GUI) guides both use and administration of the software, including the secure provision of pre-publication datasets. Third, we present genes4all_experiment, which exemplifies how our work supports the wider research community. Conclusion: Given the infrastructure presented here, the Drupal CMS may become a powerful new tool set for bioinformaticians. The GMOD-DBSF base module is an expandable community resource that decreases development time of Drupal modules for bioinformatics. The biosoftware_bench module can already enhance biologists' ability to mine their own data. The genes4all_experiment module has already been responsible for archiving of more than 150 studies of RNAi from Lepidoptera, which were previously unpublished. Availability and implementation: Implemented in PHP and Perl. Freely available under the GNU Public License 2 or later from http://gmod-dbsf.googlecode.com Contact: alexie@butterflybase.org PMID:20971988

  14. Current opinion: What is a nanoplastic?

    PubMed

    Gigault, Julien; Halle, Alexandra Ter; Baudrimont, Magalie; Pascal, Pierre-Yves; Gauffre, Fabienne; Phi, Thuy-Linh; El Hadri, Hind; Grassl, Bruno; Reynaud, Stéphanie

    2018-04-01

    With the large amount of attention being given to microplastics in the environment, several researchers have begun to consider the fragmentation of plastics down to lower scales (i.e., the sub-micrometer scale). The term "nanoplastics" is still under debate, and different studies have set the upper size limit at either 1000 nm or 100 nm. The aim of the present work is to propose a definition of nanoplastics, based on our recently published and unpublished research definition of nanoplastics. We define nanoplastics as particles unintentionally produced (i.e. from the degradation and the manufacturing of the plastic objects) and presenting a colloidal behavior, within the size range from 1 to 1000 nm. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. Low frequency baleen whale calls detected on ocean-bottom seismometers in the Lau basin, southwest Pacific Ocean.

    PubMed

    Brodie, Dana C; Dunn, Robert A

    2015-01-01

    Ten months of broadband seismic data, recorded on six ocean-bottom seismographs located in the Lau Basin, were examined to identify baleen whale species. As the first systematic survey of baleen whales in this part of the southwest Pacific Ocean, this study reveals the variety of species present and their temporal occurrence in and near the basin. Baleen whales produce species-specific low frequency calls that can be identified by distinct patterns in data spectrograms. By matching spectrograms with published accounts, fin, Bryde's, Antarctic blue, and New Zealand blue whale calls were identified. Probable whale sounds that could not be matched to published spectrograms, as well as non-biologic sounds that are likely of volcanogenic origin, were also recorded. Detections of fin whale calls (mid-June to mid-October) and blue whale calls (June through September) suggest that these species migrate through the region seasonally. Detections of Bryde's whale calls (primarily February to June, but also other times of the year) suggest this species resides around the basin nearly year round. The discovery of previously unpublished call types emphasizes the limited knowledge of the full call repertoires of baleen whales and the utility of using seismic survey data to enhance understanding in understudied regions.

  16. The Surtsey Magma Series

    PubMed Central

    Ian Schipper, C.; Jakobsson, Sveinn P.; White, James D.L.; Michael Palin, J.; Bush-Marcinowski, Tim

    2015-01-01

    The volcanic island of Surtsey (Vestmannaeyjar, Iceland) is the product of a 3.5-year-long eruption that began in November 1963. Observations of magma-water interaction during pyroclastic episodes made Surtsey the type example of shallow-to-emergent phreatomagmatic eruptions. Here, in part to mark the 50th anniversary of this canonical eruption, we present previously unpublished major-element whole-rock compositions, and new major and trace-element compositions of sideromelane glasses in tephra collected by observers and retrieved from the 1979 drill core. Compositions became progressively more primitive as the eruption progressed, with abrupt changes corresponding to shifts between the eruption’s four edifices. Trace-element ratios indicate that the chemical variation is best explained by mixing of different proportions of depleted ridge-like basalt, with ponded, enriched alkalic basalt similar to that of Iceland’s Eastern Volcanic Zone; however, the systematic offset of Surtsey compositions to lower Nb/Zr than other Vestmannaeyjar lavas indicates that these mixing end members are as-yet poorly contained by compositions in the literature. As the southwestern-most volcano in the Vestmannaeyjar, the geochemistry of the Surtsey Magma Series exemplifies processes occurring within ephemeral magma bodies on the extreme leading edge of a propagating off-axis rift in the vicinity of the Iceland plume. PMID:26112644

  17. miRanalyzer: an update on the detection and analysis of microRNAs in high-throughput sequencing experiments

    PubMed Central

    Hackenberg, Michael; Rodríguez-Ezpeleta, Naiara; Aransay, Ana M.

    2011-01-01

    We present a new version of miRanalyzer, a web server and stand-alone tool for the detection of known and prediction of new microRNAs in high-throughput sequencing experiments. The new version has been notably improved regarding speed, scope and available features. Alignments are now based on the ultrafast short-read aligner Bowtie (granting also colour space support, allowing mismatches and improving speed) and 31 genomes, including 6 plant genomes, can now be analysed (previous version contained only 7). Differences between plant and animal microRNAs have been taken into account for the prediction models and differential expression of both, known and predicted microRNAs, between two conditions can be calculated. Additionally, consensus sequences of predicted mature and precursor microRNAs can be obtained from multiple samples, which increases the reliability of the predicted microRNAs. Finally, a stand-alone version of the miRanalyzer that is based on a local and easily customized database is also available; this allows the user to have more control on certain parameters as well as to use specific data such as unpublished assemblies or other libraries that are not available in the web server. miRanalyzer is available at http://bioinfo2.ugr.es/miRanalyzer/miRanalyzer.php. PMID:21515631

  18. Infant mortality in the Marshall Islands.

    PubMed

    Levy, S J; Booth, H

    1988-12-01

    Levy and Booth present previously unpublished infant mortality rates for the Marshall Islands. They use an indirect method to estimate infant mortality from the 1973 and 1980 censuses, then apply indirect and direct methods of estimation to data from the Marshall Islands Women's Health Survey of 1985. Comparing the results with estimates of infant mortality obtained from vital registration data enables them to estimate the extent of underregistration of infant deaths. The authors conclude that 1973 census appears to be the most valid information source. Direct estimates from the Women's Health Survey data suggest that infant mortality has increased since 1970-1974, whereas the indirect estimates indicate a decreasing trend in infant mortality rates, converging with the direct estimates in more recent years. In view of increased efforts to improve maternal and child health in the mid-1970s, the decreasing trend is plausible. It is impossible to estimate accurately infant mortality in the Marshall Islands during 1980-1984 from the available data. Estimates based on registration data for 1975-1979 are at least 40% too low. The authors speculate that the estimate of 33 deaths per 1000 live births obtained from registration data for 1984 is 40-50% too low. In round figures, a value of 60 deaths per 1000 may be taken as the final estimate for 1980-1984.

  19. Larger foraminifera of the Devil's Den and Blue Hole sinkholes, Florida

    NASA Astrophysics Data System (ADS)

    Cotton, Laura J.; Eder, Wolfgang; Floyd, James

    2018-03-01

    Shallow-water carbonate deposits are well-known from the Eocene of the US Gulf Coast and Caribbean. These deposits frequently contain abundant larger benthic foraminifera (LBF). However, whilst integrated stratigraphic studies have helped to refine the timing of LBF overturning events within the Tethys and Indo-Pacific regions with respect to global bio- and chemo-stratigraphic records, little recent work has been carried out in the Americas. The American LBF assemblages are distinctly different from those of Europe and the Indo-Pacific. It is therefore essential that the American bio-province is included in studies of LBF evolution, biodiversity and climate events to understand these processes on a global scale.Here we present the LBF ranges from two previously unpublished sections spanning 35 and 29 m of the upper Eocene Ocala limestone, as the early stages of a larger project addressing the taxonomy and biostratigraphy of the LBF of Florida. The study indicates that the lower member of the Ocala limestone may be Bartonian rather than Priabonian in age, with implications for the biostratigraphy of the region. In addition, the study highlights the need for multiple sites to assess the LBF assemblages and fully constrain ranges across Florida and the US Gulf and suggests potential LBF events for future integrated stratigraphic study.

  20. Isotopic studies of the diet of the people of the coast of British Columbia.

    PubMed

    Schwarcz, Henry P; Chisholm, Brian S; Burchell, Meghan

    2014-11-01

    In 1982, Chisholm et al. used δ(13) C data for human burials from shell midden sites widely distributed on the coast of British Columbia (BC) to show the extreme dependence of these individuals on high trophic level marine consumers, principally salmon and marine mammals. Here, we present previously unpublished analyses of δ(15) N for some of the same individuals as well as δ(13) C data for additional individuals. Nitrogen isotope data show that the diet was dominated by high trophic level marine fauna including carnivorous fish and marine mammals. Although most burials were found in shell middens, marine mollusks made up of only a minor component of diet. The data for δ(13) C demonstrate that terrestrial faunal foods are undetectable in the diet of the majority of individuals, and seldom constitute more than 10% of the dietary protein of individuals living on the coast although terrestrial fauna were widely available as a potential source of protein. This dietary pattern of exclusion of land-based animals from their diet persisted for almost 6,000 years along a wide expanse of coastline. In contrast, people from the BC interior (100 km or more from the coast) consumed a mixed diet of terrestrial and marine foods including spawning salmon. © 2014 Wiley Periodicals, Inc.

  1. Advanced body composition assessment: from body mass index to body composition profiling.

    PubMed

    Borga, Magnus; West, Janne; Bell, Jimmy D; Harvey, Nicholas C; Romu, Thobias; Heymsfield, Steven B; Dahlqvist Leinhard, Olof

    2018-06-01

    This paper gives a brief overview of common non-invasive techniques for body composition analysis and a more in-depth review of a body composition assessment method based on fat-referenced quantitative MRI. Earlier published studies of this method are summarized, and a previously unpublished validation study, based on 4753 subjects from the UK Biobank imaging cohort, comparing the quantitative MRI method with dual-energy X-ray absorptiometry (DXA) is presented. For whole-body measurements of adipose tissue (AT) or fat and lean tissue (LT), DXA and quantitative MRIs show excellent agreement with linear correlation of 0.99 and 0.97, and coefficient of variation (CV) of 4.5 and 4.6 per cent for fat (computed from AT) and LT, respectively, but the agreement was found significantly lower for visceral adipose tissue, with a CV of >20 per cent. The additional ability of MRI to also measure muscle volumes, muscle AT infiltration and ectopic fat, in combination with rapid scanning protocols and efficient image analysis tools, makes quantitative MRI a powerful tool for advanced body composition assessment. © American Federation for Medical Research (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  2. Associated aneurysmal bone cyst and cemento-osseous dysplasia: a case report and review of the literature.

    PubMed

    Jacomacci, Willian Pecin; Veloso Perdigão, João Paulo; Veltrini, Vanessa Cristina; Farah, Gustavo Jacobucci; Tolentino, Elen Souza; Vessoni Iwaki, Lilian Cristina; Iwaki Filho, Liogi

    2017-01-01

    The purpose of this case report is to describe a previously unpublished association between focal cemento-osseous dysplasia (FCOD) and an aneurysmal bone cyst (ABC) and review the literature with regard to associated benign fibro-osseous lesions and cysts. A 41-year-old woman without a history of trauma presented with asymptomatic swelling in the right side of the mandible. Radiographs of the region revealed a unilocular radiolucent area with radiopaque foci. After aspiration of the lesion was positive for serosanguineous fluid, complete excision of the lesion was performed. Microscopic examination revealed a hybrid ABC and FCOD. The 12-month follow-up showed significant bone repair and no signs of recurrence. A review of the English-language literature from 1980 to 2012 revealed 1 retrospective study, 4 case series, and 18 single-case reports on the topic of cemento-osseous dysplasias, fibro-osseous lesions, and aneurysmal bone cysts. Of 59 cases, none reported an association between an ABC and FCOD. Although fibro-osseous lesions do not require intervention, surgical excision is recommended when they are associated with cysts. This case, in which an ABC and FCOD were associated, reinforces the need for a careful diagnostic process in radiographically mixed lesions that respond positively to aspiration biopsy.

  3. Energy map of southwestern Wyoming, Part A - Coal and wind

    USGS Publications Warehouse

    Biewick, Laura; Jones, Nicholas R.

    2012-01-01

    To further advance the objectives of the Wyoming Landscape Conservation Initiative (WLCI) the U.S. Geological Survey (USGS) and the Wyoming State Geological Survey (WSGS) have compiled Part A of the Energy Map of Southwestern Wyoming. Focusing primarily on electrical power sources, Part A of the energy map is a compilation of both published and previously unpublished coal (including coalbed gas) and wind energy resources data, presented in a Geographic Information System (GIS) data package. Energy maps, data, documentation and spatial data processing capabilities are available in a geodatabase, published map file (pmf), ArcMap document (mxd), Adobe Acrobat PDF map (plate 1) and other digital formats that can be downloaded at the USGS website. Accompanying the map (plate 1) and the geospatial data are four additional plates that describe the geology, energy resources, and related infrastructure. These tabular plates include coal mine (plate 2), coal field (plate 3), coalbed gas assessment unit (plate 4), and wind farm (plate 5) information with hyperlinks to source publications and data on the internet. The plates can be printed and examined in hardcopy, or accessed digitally. The data represent decades of research by the USGS, WSGS, BLM and others, and can facilitate landscape-level science assessments, and resource management decisionmaking.

  4. Kinetic analysis of reactions of Si-based epoxy resins by near-infrared spectroscopy, 13C NMR and soft-hard modelling.

    PubMed

    Garrido, Mariano; Larrechi, Maria Soledad; Rius, F Xavier; Mercado, Luis Adolfo; Galià, Marina

    2007-02-05

    Soft- and hard-modelling strategy was applied to near-infrared spectroscopy data obtained from monitoring the reaction between glycidyloxydimethylphenyl silane, a silicon-based epoxy monomer, and aniline. On the basis of the pure soft-modelling approach and previous chemical knowledge, a kinetic model for the reaction was proposed. Then, multivariate curve resolution-alternating least squares optimization was carried out under a hard constraint, that compels the concentration profiles to fulfil the proposed kinetic model at each iteration of the optimization process. In this way, the concentration profiles of each species and the corresponding kinetic rate constants of the reaction, unpublished until now, were obtained. The results obtained were contrasted with 13C NMR. The joint interval test of slope and intercept for detecting bias was not significant (alpha=5%).

  5. From a philanthropic idea to building of civic hospital in Split in light of new archival evidence.

    PubMed

    Brisky, Livia; Fatović-Ferencić, Stella

    2006-02-01

    We investigated the circumstances of building of the Civic Hospital in Split in the light of new archival evidence. The study necessitated a thorough review of the older historiography and previously unpublished archival sources kept in the State Archives in Venice and Zadar. The findings showed that construction of the hospital building finished in 1797, ie, five years later than officially cited. The topographical plan and the original project of the Split Civic Hospital were found, as well as the name of the project's author and the building supervisor. The data on the earliest efforts of Ergovac brothers to acquire land and building permission were corrected. The study revealed a recognizable pattern in the attitude of the authorities toward the establishment of a hospital at the end of 18th century.

  6. On the security of a simple three-party key exchange protocol without server's public keys.

    PubMed

    Nam, Junghyun; Choo, Kim-Kwang Raymond; Park, Minkyu; Paik, Juryon; Won, Dongho

    2014-01-01

    Authenticated key exchange protocols are of fundamental importance in securing communications and are now extensively deployed for use in various real-world network applications. In this work, we reveal major previously unpublished security vulnerabilities in the password-based authenticated three-party key exchange protocol according to Lee and Hwang (2010): (1) the Lee-Hwang protocol is susceptible to a man-in-the-middle attack and thus fails to achieve implicit key authentication; (2) the protocol cannot protect clients' passwords against an offline dictionary attack; and (3) the indistinguishability-based security of the protocol can be easily broken even in the presence of a passive adversary. We also propose an improved password-based authenticated three-party key exchange protocol that addresses the security vulnerabilities identified in the Lee-Hwang protocol.

  7. On the Security of a Simple Three-Party Key Exchange Protocol without Server's Public Keys

    PubMed Central

    Nam, Junghyun; Choo, Kim-Kwang Raymond; Park, Minkyu; Paik, Juryon; Won, Dongho

    2014-01-01

    Authenticated key exchange protocols are of fundamental importance in securing communications and are now extensively deployed for use in various real-world network applications. In this work, we reveal major previously unpublished security vulnerabilities in the password-based authenticated three-party key exchange protocol according to Lee and Hwang (2010): (1) the Lee-Hwang protocol is susceptible to a man-in-the-middle attack and thus fails to achieve implicit key authentication; (2) the protocol cannot protect clients' passwords against an offline dictionary attack; and (3) the indistinguishability-based security of the protocol can be easily broken even in the presence of a passive adversary. We also propose an improved password-based authenticated three-party key exchange protocol that addresses the security vulnerabilities identified in the Lee-Hwang protocol. PMID:25258723

  8. A Systematic Review and Quantitative Meta-Analysis of Oxytocin's Effects on Feeding.

    PubMed

    Leslie, Monica; Silva, Paulo; Paloyelis, Yannis; Blevins, James; Treasure, Janet

    2018-02-26

    Oxytocin's anorexigenic effects have been widely documented and accepted; however, no paper has yet used the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines to compile previous findings in a single systematic review and quantitative meta-analysis. The current paper aimed to identify published and unpublished studies examining the effects of oxytocin on energy intake in animals and humans, and the factors that moderate this effect. Web of Science, Pub Med, and Ovid were searched for published and unpublished studies reporting the effects of oxytocin on energy intake in wild-type animals and in humans, when administered in the absence of other active drugs or surgery. 2049 articles were identified through the original systematic literature search, from which 54 articles were identified as relevant for inclusion in this review. An additional 3 relevant articles were identified in a later update of the literature search. Overall, a single-dose of oxytocin was found to reduce feeding in animals. Despite several individual studies which found that this effect persists to the end of the third week of chronic administration in rodent models, overall, this anorexigenic effect did not hold in the meta-analyses testing the effects of chronic administration. There was no overall effect of oxytocin on energy intake in humans, although a trend was identified for oxytocin to reduce consumption of solid foods. Oxytocin reduces energy intake when administered as a single dose. Oxytocin can inhibit feeding over two- to three-week periods in rodent models. These effects typically do not persist beyond the third week of treatment. The anorexigenic effect of oxytocin is moderated by pregnant status, dose, method of administration, and diet composition. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  9. Sodium channel blockers for cystic fibrosis.

    PubMed

    Burrows, E; Southern, K W; Noone, P

    2006-07-19

    People with cystic fibrosis (CF) have increased transport of the salt, sodium across their airway lining. Over-absorption of sodium results in the dehydration of the liquid that lines the airway surface and is a primary defect in people with CF. To determine whether the topical administration of drugs that block sodium transport improves the respiratory condition of people with CF. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Trials Register comprising references identified from comprehensive electronic database searches, handsearching relevant journals and abstract books of conference proceedings. We contacted principal investigators known to work in the field, previous authors and pharmaceutical companies who manufacture ion transport agents for unpublished or follow-up data. Most recent search of the Group's register: March 2006 Published or unpublished randomised controlled trials (RCTs) or quasi-randomised controlled trials of sodium channel blockers compared to placebo or another sodium channel blocker or the same sodium channel blocker at a different dosing regimen. Two authors independently extracted data. Meta-analysis was limited due to differing study designs. Four RCTs, with a total of 205 participants, examining the topical administration of the short-acting sodium channel blocker, amiloride, compared to placebo were identified as eligible for inclusion in the review. For three studies, interventions for six months were completed and it was possible to calculate relative change in respiratory function (FVC). There was a significant difference found in relative change in FVC in favour of placebo (GIV analysis of weighted mean difference for FVC; 1.51% (95% confidence interval -2.77 to -0.25). There were no significant differences identified in other clinically relevant outcomes. We found no evidence that the topical administration of a short-acting sodium channel blocker improves respiratory condition in people with cystic fibrosis and some limited evidence of deterioration in lung function.

  10. 8-Way Randomized Controlled Trial of Doxylamine, Pyridoxine and Dicyclomine for Nausea and Vomiting during Pregnancy: Restoration of Unpublished Information

    PubMed Central

    Zhang, Rujun; Persaud, Navindra

    2017-01-01

    Objectives We report information about an unpublished 1970s study (“8-way” Bendectin Study) that aimed to evaluate the relative therapeutic efficacy of doxylamine, pyridoxine, and dicyclomine in the management of nausea and vomiting during pregnancy. We are publishing the trial's findings according to the restoring invisible and abandoned trials (RIAT) initiative because the trial was never published. Design Double blinded, multi-centred, randomized placebo-controlled study. Setting 14 clinics in the United States. Participants 2308 patients in the first 12 weeks of pregnancy with complaints of nausea or vomiting were enrolled. Interventions Each patient was randomized to one of eight arms: placebo, doxylamine/pyridoxine/dicylcomine, doxylamine/pyridoxine, dicylomine/pyridoxine, doxylamine, dicyclomine/pyridoxine, pyridoxine and dicyclomine. Each patient was instructed to take 2 tablets at bedtime and 1 additional tablet in the afternoon or morning if needed, for 7 nights. Outcomes Reported outcomes included the number of hours of nausea reported by patients, the frequency of vomiting reported by patients and the overall efficacy of medication as judged by physicians. Results Data from 1599 (69% of those randomized) participants were analyzed. Based on the available summary data of physician evaluation of symptoms and ignoring missing data and data integrity issues, the proportion of participants who were “evaluated moderate or excellent” was greater in each of the seven active treatment groups when compared with placebo (57%): doxylamine/pyridoxine/dicylcomine (14% absolute difference versus placebo; 95% CI: 4 to 24), doxylamine/pyridoxine (21; 95% CI 11 to 30), dicylomine/pyridoxine (21; 95% CI 11 to 30), doxylamine (20; 95% CI 10 to 29), dicyclomine/pyridoxine (4; 95% CI -6 to 14), pyridoxine (9; 95% CI -1 to 19) and dicyclomine (4; 95% CI -6 to 14). Based on incomplete information, the most common adverse events were apparently drowsiness and fatigue. There is a high risk of bias in these previously unpublished results given the high attrition rate in a 7 day trial, the lack of prespecified outcomes or analyses, and the exclusion of some data because of questionable data integrity. Conclusion The available information about this “8-way Bendectin” trial indicates it should not be used to support the efficacy of doxylamine, pyridoxine or dicyclomine for the treatment of nausea and vomiting during pregnancy because of a high risk of bias. Trial registration Not registered. PMID:28052111

  11. Effects of management practices on wetland birds: Yellow Rail

    USGS Publications Warehouse

    Goldade, Christopher M.; Dechant, Jill A.; Johnson, Douglas H.; Zimmerman, Amy L.; Jamison, Brent E.; Church, James O.; Euliss, Betty R.

    2002-01-01

    Information on the habitat requirements and effects of habitat management on wetland birds were summarized from information in more than 500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although the BBS may not capture the presence of elusive waterbird species, the BBS is a standardized survey and the range maps, in many cases, represent the most consistent information available on species’ distributions. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The section on brood parasitism summarizes information on intra- and interspecific parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species’ nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species’ response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes recommendations for habitat management provided in the literature. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of wetland birds and their responses to habitat management is posted at the Web site mentioned below.

  12. Effects of management practices on wetland birds: Virginia rail

    USGS Publications Warehouse

    Zimmerman, Amy L.; Dechant, Jill A.; Jamison, Brent E.; Johnson, Douglas H.; Goldade, Christopher M.; Church, James O.; Euliss, Betty R.

    2002-01-01

    Information on the habitat requirements and effects of habitat management on wetland birds were summarized from information in more than 500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although the BBS may not capture the presence of elusive waterbird species, the BBS is a standardized survey and the range maps, in many cases, represent the most consistent information available on species’ distributions. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The section on brood parasitism summarizes information on intra- and interspecific parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species’ nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species’ response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes recommendations for habitat management provided in the literature. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of wetland birds and their responses to habitat management is posted at the Web site mentioned below.

  13. Effects of management practices on grassland birds: Lesser Prairie-Chicken

    USGS Publications Warehouse

    Jamison, Brent E.; Dechant, Jill A.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Euliss, Betty R.

    2002-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 4,000 published and unpublished papers. A range map is provided to indicate the breeding distribution of Lesser Prairie-Chicken in the United States and southern Canada. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species’ nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species’ response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species’ breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management is posted at the Web site mentioned below.

  14. Effects of management practices on wetland birds: Black tern

    USGS Publications Warehouse

    Zimmerman, Amy L.; Dechant, Jill A.; Johnson, Douglas A.; Goldade, Christopher M.; Jamison, Brent E.; Euliss, Betty R.

    2002-01-01

    Information on the habitat requirements and effects of habitat management on wetland birds were summarized from information in more than 500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although the BBS may not capture the presence of elusive waterbird species, the BBS is a standardized survey and the range maps, in many cases, represent the most consistent information available on species’ distributions. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The section on brood parasitism summarizes information on intra- and interspecific parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species’ nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species’ response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes recommendations for habitat management provided in the literature. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management is posted at the Web site mentioned below.

  15. Effects of management practices on grassland birds: Brewer's sparrow

    USGS Publications Warehouse

    Walker, Brett L.

    2004-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species’ nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species’ response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species’ breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management is posted at the Web site mentioned below.

  16. Effects of management practices on wetland birds: American Avocet

    USGS Publications Warehouse

    Dechant, Jill A.; Zimmerman, Amy L.; Johnson, Douglas H.; Goldade, Christopher M.; Jamison, Brent E.; Euliss, Betty R.

    2002-01-01

    Information on the habitat requirements and effects of habitat management on wetland birds were summarized from information in more than 500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although the BBS may not capture the presence of elusive waterbird species, the BBS is a standardized survey and the range maps, in many cases, represent the most consistent information available on species’ distributions. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The section on brood parasitism summarizes information on intra- and interspecific parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species’ nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species’ response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes recommendations for habitat management provided in the literature. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of wetland birds and their responses to habitat management is posted at the Web site mentioned below.

  17. Effects of management practices on grassland birds: Greater Sage-Grouse

    USGS Publications Warehouse

    Rowland, Mary M.

    2004-01-01

    Information on the habitat requirements and effects of habitat management on Greater Sage-Grouse was summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the current range of Greater Sage-Grouse (adapted from Schroeder et al. 2004). Although birds may be observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species’ nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species’ response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species’ breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of shrub-steppe birds and their responses to habitat management is posted at the Web site mentioned below.

  18. Effects of management practices on grassland birds: Merlin

    USGS Publications Warehouse

    Konrad, Paul M.

    2004-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the breeding, year-round, and nonbreeding ranges in the United States and southern Canada. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species’ nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species’ response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species’ breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management is posted at the Web site mentioned below.

  19. Effects of management practices on grassland birds: Golden eagle

    USGS Publications Warehouse

    DeLong, John P.

    2004-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 4,000 published and unpublished papers. A range map is provided to the breeding, year-round, and nonbreeding ranges in the United States and southern Canada. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species’ nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species’ response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species’ breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management is posted at the Web site mentioned below.

  20. VizieR Online Data Catalog: Orbits based on speckle interferometry at SOAR (Tokovinin, 2016)

    NASA Astrophysics Data System (ADS)

    Tokovinin, A.

    2017-03-01

    This paper presents new or updated orbits for 55 binary systems or subsystems. It is based on speckle interferometric measurements made at the 4.1m Southern Astrophyisical Research (SOAR) telescope combined with archival data collected in the Washington Double Star Catalog (WDS; Mason et al. 2001-2014, Cat. B/wds). Table1 lists the orbital elements and their errors in common notation. Individual observations and residuals are listed in Table2. It contains still unpublished measures made at SOAR in 2016, while some published SOAR measures were reprocessed. Table3 provides additional information. (4 data files).

  1. Interactive design of generic chemical patterns.

    PubMed

    Schomburg, Karen T; Wetzer, Lars; Rarey, Matthias

    2013-07-01

    Every medicinal chemist has to create chemical patterns occasionally for querying databases, applying filters or describing functional groups. However, the representations of chemical patterns have been so far limited to languages with highly complex syntax, handicapping the application of patterns. Graphic pattern editors similar to chemical editors can facilitate the work with patterns. In this article, we review the interfaces of frequently used web search engines for chemical patterns. We take a look at pattern editing concepts of standalone chemical editors and finally present a completely new, unpublished graphical approach to pattern design, the SMARTSeditor. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Models of the Neuronal Mechanisms of Target Localization of the Barn Owl

    DTIC Science & Technology

    1990-12-01

    1991 Air Force ANO9 91 Office of Scientific Research B I___ ,V’.’.’ 2 • p ,,i lil l II II I I I II Il I I I I I I I I0 REPORT DOCUMENTATION PAGE F...much more significance at this time. Task 1 will be performed as time and interest dictate. B . Task 2 Neurons in nucleus laminaris receive input from...is included in Appendix B . Other recent unpublished experimental findings support the mod- els. In fact, the poster to be presented by Dr. Pearson at

  3. Evaluation of the Initiation/Promotion Potential of CTFE Trimer Acid

    DTIC Science & Technology

    1990-11-01

    0 1 0 0 0 0 0 0 0 Atrophic hepatic cords 3 Cc Cc Cc Cc Cc Cc Cc 3 0e Ce Ce 0e Ge 0e Ce Steatosis 3 2 4 4 4 4 4 3 2 1 0 2 2 1 2 1 Kuppfercell pigment...with the formation of hepatic tumors. Therefore, the present study was designed to evaluate CTFE trimer acid for both tumor initiation and promoting...oxidation of palmitoyl coenzyme A (CoA) MOelRaso, unpublished findings). Many compounds cause an increase in the number of hepatic peroxisomes and are

  4. Santiago Ramón y Cajal and three-dimensional cinema.

    PubMed

    Santarén, Juan Fernández

    2015-01-01

    In this article, I present and comment on two unpublished letters written by the Spanish engineer Carlos Mendizábal Brunet to Santiago Ramón y Cajal informing him of the development of a new device for three-dimensional cinema and asking for his approval. Fortunately, the answers given by Cajal to these two letters have also been preserved, and they reveal his interest in three-dimensional cinema; in the letters, he reported that he himself had designed a prototype capable of creating on a screen a feeling of 3-D relief, a subject about which he was always passionate.

  5. [The Grand Prince G.A. Romanov and the diagnostic capabilities of XIX century medicine].

    PubMed

    Kovalev, A V; Molin, Yu A

    This article is devoted to the medical aspects of the biography of the Grand Prince Georgiy Romanov, the younger brother of Nikolas II, the Russian Emperor. It reports the results of the analysis of the formerly unpublished documents stored in the funds of the Russian State Historical Archive (RGIA). The authors present the data characterizing the level of medical care provided to the patients in Russia of that time. In addition, they describe the specific morphological patterns of pulmonary tuberculosis which affected the Crown Prince and became the cause of his death.

  6. Extrasystoles: side effect of kangaroo care?

    PubMed

    Kluthe, Christof; Wauer, Roland R; Rüdiger, Mario

    2004-09-01

    To present an unpublished reason for an arrhythmic electrocardiogram (ECG) recording during kangaroo care in a preterm infant. Case report. Preterm infant. A preterm infant exhibited cardiac arrhythmia on the ECG monitor during kangaroo care, leading to interruption of kangarooing. Arrhythmia disappeared after placing the baby back into the incubator. The most likely reasons for arrhythmia were excluded. However, arrhythmia reappeared upon continuation of kangaroo care. ECG monitoring revealed the reason for the monitoring error. ECG monitoring during kangaroo care should cause error because of superimposed electric activity from the parent. Oxygen saturation represents a more reliable method of monitoring during kangaroo care.

  7. Freshwater fishes of Acadia National Park, Mount Desert Island, Maine

    USGS Publications Warehouse

    Stone, J.; Le, B.C.; Moring, J.R.

    2001-01-01

    A list of freshwater fishes is presented for Acadia National Park, Mount Desert Island, Maine, based on past survey records, published and unpublished reports, and recent comprehensive surveys within or bordering Park boundaries conducted in 1998 and 1999. Overall, 31 species of fishes have been recorded in freshwaters of the Park or those bordering Park boundaries; 28 of these are still present. Of those, 15 species are likely native to Mount Desert Island, and the indigenous status of one fish species is unknown. The most widely distributed species in lakes and ponds is the golden shiner, Notemigonus crysoleucas Mitchill (83% of ponds), while the most widely-distributed species in brooks is the brook trout, Salvelinus fontinalis Mitchill (56%).

  8. A Preliminary evaluation of hydrology and water quality near the Tacoma Landfill, Pierce County, Washington

    USGS Publications Warehouse

    Lum, W.E.; Turney, G.L.

    1985-01-01

    The Tacoma landfill, located in western Pierce County, Washington, has been used for the disposal of waste since about 1960. Disposal operations are planned to continue at this site until at least 1990. Data were compiled and interpreted to help understand the possible effects of the landfill on water quality in the surrounding area. Data were collected from published and unpublished reports of the U.S. Geological Survey, and from predominantly unpublished data in the files of other government agencies. The Tacoma landfill is underlain by unconsolidated, glacially derived deposits that consist of a wide variety of mixtures of clay to boulder-sized materials. Ground water is mostly the result of rainfall on the land surface, and moves through artesian aquifers (under the landfill) that are tapped for both domestic and municipal use. Hazardous liquid and dissolved wastes are probably present in the landfill, and potential flow paths for waste migration exist. An undetermined number of single-family domestic wells and 18 public-supply wells are within 3 miles of the landfill, three as close as 0.2 miles. There is only limited evidence indicating ground- and surface-water contamination. Further investigations of the geology, hydrology and water quality are needed to characterize the impact the landfill has on ground- and surface-water of the surrounding area. (USGS)

  9. VizieR Online Data Catalog: NGC 5548 43 year-long monitoring in Hβ (Bon+, 2016)

    NASA Astrophysics Data System (ADS)

    Bon, E.; Zucker, S.; Netzer, H.; Marziani, P.; Bon, N.; Jovanovic, P.; Shapovalova, A. I.; Komossa, S.; Gaskell, C. M.; Popovic, L. C.; Britzen, S.; Chavushyan, V. H.; Burenkov, A. N.; Sergeev, S.; La Mura, G.; Valdes, J. R.; Stalevski, M.

    2016-10-01

    We analyzed 1600 spectra of NGC 5548 in the Hβ spectral interval, covering 43 years. We used: (a) archival spectra obtained by K.K. Chuvaev from 1972-1988 (Sergeev+ 2007ApJ...668..708S) prior to the International AGN Watch (IAW) campaigns. These early spectra were recorded on photographic plates acquired with an image tube at the 2.6m Shajn Telescope of the Crimean Astrophysical Observatory. (b) The 13 year study (from 1988 to 2002) of the IAW program (Peterson+ 2002ApJ...581..197P), which provided 1530 optical continuum measurements and 1248 Hβ measurements. (c) A spectral monitoring program with the 6 and 1m telescopes of the Special Astrophysical Observatory (SAO) in Russia from 1996 to 2002, and the 2.1m telescope of Guillermo Haro Observatory (GHO) in Cananea, Mexico, from 1996 to 2003 (S04; Shapovalova+ 2004, J/A+A/422/925). (d) More recent, unpublished observations of the same program covering 2003-2013 observed at SAO (see Table 1), and a continuation of the monitoring campaign presented in S04. (e) Spectra from the new IAW campaign obtained at Asiago observatory in 2012, 2013, and 2015. (f) New unpublished observations from 2013 from the Asiago observatory (also given in Table 1). See section 2 for further details. (2 data files).

  10. Peter J Derrick and the Grand Scale 'Magnificent Mass Machine' mass spectrometer at Warwick.

    PubMed

    Colburn, A W; Derrick, Peter J; Bowen, Richard D

    2017-12-01

    The value of the Grand Scale 'Magnificent Mass Machine' mass spectrometer in investigating the reactivity of ions in the gas phase is illustrated by a brief analysis of previously unpublished work on metastable ionised n-pentyl methyl ether, which loses predominantly methanol and an ethyl radical, with very minor contributions for elimination of ethane and water. Expulsion of an ethyl radical is interpreted in terms of isomerisation to ionised 3-pentyl methyl ether, via distonic ions and, possibly, an ion-neutral complex comprising ionised ethylcyclopropane and methanol. This explanation is consistent with the closely similar behaviour of the labelled analogues, C 3 H 7 CH 2 CD 2 OCH 3 +. and C 3 H 7 CD 2 CH 2 OCH 3 +. , and is supported by the greater kinetic energy release associated with loss of ethane from ionised n-propyl methyl ether compared to that starting from directly generated ionised 3-pentyl methyl ether.

  11. Circumvertical reduction mastoplasty: new considerations.

    PubMed

    Mottura, A Aldo

    2003-01-01

    The circumvertical technique is a mixture of the periareolar and the vertical techniques in which the skin resection is performed around the areola and is continued in an inverted cone that starts at the infraareolar area and ends 2-4 cm above the submammary crease. Some advantages of this technique are: The glands are removed from the inferior glandular quadrant and from the inferior borders of the lateral and medial quadrants. The areola is moved upward and attached to the gland, preserving the nursing function. There is a harmonious distribution of the pleats around the areola and at the vertical wound. The vertical suture never crosses the submammary crease. The postoperative result is acceptable. Local anesthesia with vasoconstrictor is used minimizing bleeding. Bupivacaine is also included, prolonging the anesthetic effect hours after surgery. This paper describes this simple and rapid surgery and discusses some new, previously unpublished considerations and tricks.

  12. [1400 hours of analysis with Freud: Viktor von Dirsztay. A biographical sketch].

    PubMed

    May, Ulrike

    2010-01-01

    On the basis of mostly unpublished sources, the author reconstructs the life of the Hungarian writer Viktor von Dirsztay (1884?-1935) who was personally acquainted with many expressionist artists and writers, e. g. with Karl Kraus, Oskar Kokoschka, Herwarth Walden, Walter Hasenclever, Hermann Broch and Arthur Schnitzler. This association puts Freud into closer proximity with the cultural avantgarde of his times than previously realized. Between 1910 and 1920 Dirsztay underwent several phases of analysis with Freud; then he was treated by Theodor Reik. The overall length of his analysis with Freud is almost unparalleled. The article discusses whether and in which way Dirsztay's writings might have been influenced by his analyses and how Freud and Reik might have drawn upon their experiences with this patient. It is argued that likely references can be discovered in both authors' theories of masochism. There is an intriguing late remark of Dirsztay's that he was "ruined by analysis".

  13. Group sessions with Paro in a nursing home: Structure, observations and interviews.

    PubMed

    Robinson, Hayley; Broadbent, Elizabeth; MacDonald, Bruce

    2016-06-01

    We recently reported that a companion robot reduced residents' loneliness in a randomised controlled trial at an aged-care facility. This report aims to provide additional, previously unpublished data about how the sessions were run, residents' interactions with the robot and staff perspectives. Observations were conducted focusing on engagement, how residents treated the robot and if the robot acted as a social catalyst. In addition, 16 residents and 21 staff were asked open-ended questions at the end of the study about the sessions and the robot. Observations indicated that some residents engaged on an emotional level with Paro, and Paro was treated as both an agent and an artificial object. Interviews revealed that residents enjoyed sharing, interacting with and talking about Paro. This study supports other research showing Paro has psychosocial benefits and provides a guide for those wishing to use Paro in a group setting in aged care. © 2015 AJA Inc.

  14. Microbial biodiversity of the atmosphere

    NASA Astrophysics Data System (ADS)

    Klein, Ann Maureen

    Microorganisms are critical to the functioning of terrestrial and aquatic ecosystems and may also play a role in the functioning of the atmosphere. However, little is known about the diversity and function of microorganisms in the atmosphere. To investigate the forces driving the assembly of bacterial microbial communities in the atmosphere, I measured temporal variation in bacterial diversity and composition over diurnal and inter-day time scales. Results suggest that bacterial communities in the atmosphere markedly vary over diurnal time scales and are likely structured by inputs from both local terrestrial and long-distance sources. To assess the potential functions of bacteria and fungi in the atmosphere, I characterized total and potentially active communities using both RNA- and DNA-based data. Results suggest there are metabolically active microorganisms in the atmosphere that may affect atmospheric functions including precipitation development and carbon cycling. This dissertation includes previously published and unpublished co-authored material.

  15. Population density controls on microbial pollution across the Ganga catchment.

    PubMed

    Milledge, D G; Gurjar, S K; Bunce, J T; Tare, V; Sinha, R; Carbonneau, P E

    2018-01-01

    For millions of people worldwide, sewage-polluted surface waters threaten water security, food security and human health. Yet the extent of the problem and its causes are poorly understood. Given rapid widespread global urbanisation, the impact of urban versus rural populations is particularly important but unknown. Exploiting previously unpublished archival data for the Ganga (Ganges) catchment, we find a strong non-linear relationship between upstream population density and microbial pollution, and predict that these river systems would fail faecal coliform standards for irrigation waters available to 79% of the catchment's 500 million inhabitants. Overall, this work shows that microbial pollution is conditioned by the continental-scale network structure of rivers, compounded by the location of cities whose growing populations contribute c. 100 times more microbial pollutants per capita than their rural counterparts. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  16. European Archaeomagnetism: Progress and Problems

    NASA Astrophysics Data System (ADS)

    Evans, M. E.; Hoye, G.

    2009-05-01

    Much progress has been made since the seminal work of Giuseppe Folgheraiter (1856-1913) in the late 19th century. So much so that recent advances now make it possible to draw up complete isogonic and isoclinic maps for Europe and adjacent areas spanning the last three millennia (Pavon-Carrasco et al., 2009). Results based on multiple independent studies, with high precision and good age control are crucial and should be recognized as "anchor points" (e.g. Pompeii). On the other hand, the nagging problem of outliers persists. Among the possible causes are magnetic refraction, physical distortion, and inadequate chronological control. Some examples, drawn from our own investigations over the last 30 years, will be discussed in detail. These include previously unpublished data from a detailed study (more than 100 samples) of a kiln in southern Italy, and an apparently good (but aberrant) archaeodirection from a kiln in southern Spain.

  17. Evidence for recombination in scorpion mitochondrial DNA (Scorpiones: Buthidae).

    PubMed

    Gantenbein, Benjamin; Fet, Victor; Gantenbein-Ritter, Iris A; Balloux, François

    2005-04-07

    There has been very little undisputed evidence for recombination in animal mitochondrial DNA (mtDNA) provided so far. Previous unpublished results suggestive of mtDNA recombination in the scorpion family Buthidae, together with cytological evidence for a unique mechanism of mitochondrial fusion in that family, prompted us to investigate this group in more details. First, we sequenced the complete mtDNA genome of Mesobuthus gibbosus, and chose two genes opposing each other (16S and coxI). We then sequenced 150 individuals from the natural populations of four species of Buthidae (Old World genera Buthus and Mesobuthus). We observed strong evidence for widespread recombination through highly significant negative correlations between linkage disequilibrium and physical distance in three out of four species. The evidence is further confirmed when using five other tests for recombination and by the presence of a high amount of homoplasy in phylogenetic trees.

  18. Preliminary Geologic Map of the Buxton 7.5' Quadrangle, Washington County, Oregon

    USGS Publications Warehouse

    Dinterman, Philip A.; Duvall, Alison R.

    2009-01-01

    This map, compiled from previously published and unpublished data, and new mapping by the authors, represents the general distribution of bedrock and surficial deposits of the Buxton 7.5-minute quadrangle. The database delineates map units that are identified by general age and lithology following the stratigraphic nomenclature of the U.S. Geological Survey. The scale of the source maps limits the spatial resolution (scale) of the database to 1:24,000 or smaller. This plot file and accompanying database depict the distribution of geologic materials and structures at a regional (1:24,000) scale. The report is intended to provide geologic information for the regional study of materials properties, earthquake shaking, landslide potential, mineral hazards, seismic velocity, and earthquake faults. In addition, the report contains new information and interpretations about the regional geologic history and framework. However, the regional scale of this report does not provide sufficient detail for site development purposes.

  19. Programmable immersive peripheral environmental system (PIPES): a prototype control system for environmental feedback devices

    NASA Astrophysics Data System (ADS)

    Frend, Chauncey; Boyles, Michael

    2015-03-01

    This paper describes an environmental feedback device (EFD) control system aimed at simplifying the VR development cycle. Programmable Immersive Peripheral Environmental System (PIPES) affords VR developers a custom approach to programming and controlling EFD behaviors while relaxing the required knowledge and expertise of electronic systems. PIPES has been implemented for the Unity engine and features EFD control using the Arduino integrated development environment. PIPES was installed and tested on two VR systems, a large format CAVE system and an Oculus Rift HMD system. A photocell based end-to-end latency experiment was conducted to measure latency within the system. This work extends previously unpublished prototypes of a similar design. Development and experiments described in this paper are part of the VR community goal to understand and apply environment effects to VEs that ultimately add to users' perceived presence.

  20. Acute tryptophan depletion in humans: a review of theoretical, practical and ethical aspects

    PubMed Central

    Young, Simon N.

    2013-01-01

    The acute tryptophan depletion (ATD) technique has been used extensively to study the effect of low serotonin in the human brain. This review assesses the validity of a number of published criticisms of the technique and a number of previously unpublished potential criticisms. The conclusion is that ATD can provide useful information when results are assessed in conjunction with results obtained using other techniques. The best-established conclusion is that low serotonin function after tryptophan depletion lowers mood in some people. However, this does not mean that other variables, altered after tryptophan depletion, are necessarily related to low serotonin. Each aspect of brain function has to be assessed separately. Furthermore, a negative tryptophan depletion study does not mean that low serotonin cannot influence the variable studied. This review suggests gaps in knowledge that need to be filled and guidelines for carrying out ATD studies. PMID:23428157

  1. The Immortal Fire Within: the life and work of Edward Emerson Barnard

    NASA Astrophysics Data System (ADS)

    Sheehan, William

    1995-06-01

    This first full-length biography of Edward Emerson Barnard tells the remarkable tale of endurance and achievement of one of the leading astronomers of the late nineteenth and early twentieth century. As "a man who was never known to sleep", Barnard scoured the heavens endlessly, leaving an astonishing legacy of observations that make him one of the greatest observers of all time. This book traces Barnard's life from impoverished origins to status as an internationally recognized astronomer. His success as a professional astronomer unfolds in 1842 as he discovers the fifth satellite of Jupiter (the first since Galileo) and pioneers wide-angle photography of the Milky Way, which leads to the recognition of dark nebulae--clouds of dust on the galactic plane. Beautifully illustrated throughout, this book provides a complete history of Barnard's fascinating life and work, based largely on previously unpublished archival material, that will be of interest to astronomers and historians of science.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kaufman, B.I.

    A power with inordinate wealth and influence, the oil industry has been seen as a sovereign entity, capable of dictating the terms and conditions under which oil is produced and sold throughout the world. The book examines the American government's attempt to curtail this international power in an antitrust suit which the Department of Justice brought in 1953 against the United States' five major oil corporations: Esso, Gulf, Mobil, Socal, and Texaco. While focusing on the cartel case, Burton Kaufman also tries to place it in the broader framework of foreign antitrust development in the Cold War era. His thesis:more » American concepts of national interest and national security, for the most part, destroyed the value of the cartel case as a curb on Mideastern oil monopolies. In support of his argument, Kaufman includes lengthy appendixes containing major documents relating to the cartel case, among them previously unpublished Justice Department records.« less

  3. Centers for Disease Control and Prevention Expert Panel Meetings on Prevention and Treatment of Anthrax in Adults

    PubMed Central

    Hendricks, Katherine A.; Wright, Mary E.; Shadomy, Sean V.; Bradley, John S.; Morrow, Meredith G.; Pavia, Andy T.; Rubinstein, Ethan; Holty, Jon-Erik C.; Messonnier, Nancy E.; Smith, Theresa L.; Pesik, Nicki; Treadwell, Tracee A.

    2014-01-01

    The Centers for Disease Control and Prevention convened panels of anthrax experts to review and update guidelines for anthrax postexposure prophylaxis and treatment. The panels included civilian and military anthrax experts and clinicians with experience treating anthrax patients. Specialties represented included internal medicine, pediatrics, obstetrics, infectious disease, emergency medicine, critical care, pulmonology, hematology, and nephrology. Panelists discussed recent patients with systemic anthrax; reviews of published, unpublished, and proprietary data regarding antimicrobial drugs and anthrax antitoxins; and critical care measures of potential benefit to patients with anthrax. This article updates antimicrobial postexposure prophylaxis and antimicrobial and antitoxin treatment options and describes potentially beneficial critical care measures for persons with anthrax, including clinical procedures for infected nonpregnant adults. Changes from previous guidelines include an expanded discussion of critical care and clinical procedures and additional antimicrobial choices, including preferred antimicrobial drug treatment for possible anthrax meningitis. PMID:24447897

  4. Centers for disease control and prevention expert panel meetings on prevention and treatment of anthrax in adults.

    PubMed

    Hendricks, Katherine A; Wright, Mary E; Shadomy, Sean V; Bradley, John S; Morrow, Meredith G; Pavia, Andy T; Rubinstein, Ethan; Holty, Jon-Erik C; Messonnier, Nancy E; Smith, Theresa L; Pesik, Nicki; Treadwell, Tracee A; Bower, William A

    2014-02-01

    The Centers for Disease Control and Prevention convened panels of anthrax experts to review and update guidelines for anthrax postexposure prophylaxis and treatment. The panels included civilian and military anthrax experts and clinicians with experience treating anthrax patients. Specialties represented included internal medicine, pediatrics, obstetrics, infectious disease, emergency medicine, critical care, pulmonology, hematology, and nephrology. Panelists discussed recent patients with systemic anthrax; reviews of published, unpublished, and proprietary data regarding antimicrobial drugs and anthrax antitoxins; and critical care measures of potential benefit to patients with anthrax. This article updates antimicrobial postexposure prophylaxis and antimicrobial and antitoxin treatment options and describes potentially beneficial critical care measures for persons with anthrax, including clinical procedures for infected nonpregnant adults. Changes from previous guidelines include an expanded discussion of critical care and clinical procedures and additional antimicrobial choices, including preferred antimicrobial drug treatment for possible anthrax meningitis.

  5. Toward an architecture of attachment disorganization: John Bowlby's published and unpublished reflections.

    PubMed

    Solomon, Judith; Duschinsky, Robbie; Bakkum, Lianne; Schuengel, Carlo

    2017-10-01

    This article examines the construct of disorganized attachment originally proposed by Main and Solomon, developing some new conjectures based on inspiration from a largely unknown source: John Bowlby's unpublished texts, housed at the Wellcome Trust Library Archive in London (with permission from the Bowlby family). We explore Bowlby's discussions of disorganized attachment, which he understood from the perspective of ethological theories of conflict behavior. Bowlby's reflections regarding differences among the behaviors used to code disorganized attachment will be used to explore distinctions that may underlie the structure of the current coding system. The article closes with an emphasis on the importance Bowlby placed on Popper's distinction between the context of discovery and the context of justification in developmental science.

  6. Miscellaneous High-Resolution Seismic Imaging Investigations in Salt Lake and Utah Valleys for Earthquake Hazards

    USGS Publications Warehouse

    Stephenson, W.J.; Williams, R.A.; Odum, J.K.; Worley, D.M.

    2007-01-01

    Introduction In support of earthquake hazards and ground motion studies by researchers at the Utah Geological Survey, University of Utah, Utah State University, Brigham Young University, and San Diego State University, the U.S. Geological Survey Geologic Hazards Team Intermountain West Project conducted three high-resolution seismic imaging investigations along the Wasatch Front between September 2003 and September 2005. These three investigations include: (1) a proof-of-concept P-wave minivib reflection imaging profile in south-central Salt Lake Valley, (2) a series of seven deep (as deep as 400 m) S-wave reflection/refraction soundings using an S-wave minivib in both Salt Lake and Utah Valleys, and (3) an S-wave (and P-wave) investigation to 30 m at four sites in Utah Valley and at two previously investigated S-wave (Vs) minivib sites. In addition, we present results from a previously unpublished downhole S-wave investigation conducted at four sites in Utah Valley. The locations for each of these investigations are shown in figure 1. Coordinates for the investigation sites are listed in Table 1. With the exception of the P-wave common mid-point (CMP) reflection profile, whose end points are listed, these coordinates are for the midpoint of each velocity sounding. Vs30 and Vs100, also shown in Table 1, are defined as the average shear-wave velocities to depths of 30 and 100 m, respectively, and details of their calculation can be found in Stephenson and others (2005). The information from these studies will be incorporated into components of the urban hazards maps along the Wasatch Front being developed by the U.S. Geological Survey, Utah Geological Survey, and numerous collaborating research institutions.

  7. Compendium of Experimental Cetane Numbers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yanowitz, Janet; Ratcliff, Matthew A.; McCormick, Robert L.

    This report is an updated version of the 2014 Compendium of Experimental Cetane Number Data and presents a compilation of measured cetane numbers for pure chemical compounds. It includes all available single-compound cetane number data found in the scientific literature up until December 2016 as well as a number of previously unpublished values, most measured over the past decade at the National Renewable Energy Laboratory. This version of the compendium contains cetane values for 496 pure compounds, including 204 hydrocarbons and 292 oxygenates. 176 individual measurements are new to this version of the compendium, all of them collected using ASTMmore » Method D6890, which utilizes an Ignition Quality Tester (IQT) a type of constant-volume combustion chamber. For many compounds, numerous measurements are included, often collected by different researchers using different methods. The text of this document is unchanged from the 2014 version, except for the numbers of compounds in Section 3.1, the Appendices, Table 1. Primary Cetane Number Data Sources and Table 2. Number of Measurements Included in Compendium. Cetane number is a relative ranking of a fuel's autoignition characteristics for use in compression ignition engines. It is based on the amount of time between fuel injection and ignition, also known as ignition delay. The cetane number is typically measured either in a single-cylinder engine or a constant-volume combustion chamber. Values in the previous compendium derived from octane numbers have been removed and replaced with a brief analysis of the correlation between cetane numbers and octane numbers. The discussion on the accuracy and precision of the most commonly used methods for measuring cetane number has been expanded, and the data have been annotated extensively to provide additional information that will help the reader judge the relative reliability of individual results.« less

  8. Structured settlement annuities, part 2: mortality experience 1967--95 and the estimation of life expectancy in the presence of excess mortality.

    PubMed

    Singer, R B; Schmidt, C J

    2000-01-01

    the mortality experience for structured settlement (SS) annuitants issued both standard (Std) and substandard (SStd) has been reported twice previously by the Society of Actuaries (SOA), but the 1995 mortality described here has not previously been published. We describe in detail the 1995 SS mortality, and we also discuss the methodology of calculating life expectancy (e), contrasting three different life-table models. With SOA permission, we present in four tables the unpublished results of its 1995 SS mortality experience by Std and SStd issue, sex, and a combination of 8 age and 6 duration groups. Overall results on mortality expected from the 1983a Individual Annuity Table showed a mortality ratio (MR) of about 140% for Std cases and about 650% for all SStd cases. Life expectancy in a group with excess mortality may be computed by either adding the decimal excess death rate (EDR) to q' for each year of attained age to age 109 or multiplying q' by the decimal MR for each year to age 109. An example is given for men age 60 with localized prostate cancer; annual EDRs from a large published cancer study are used at duration 0-24 years, and the last EDR is assumed constant to age 109. This value of e is compared with e from constant initial values of EDR or MR after the first year. Interrelations of age, sex, e, and EDR and MR are discussed and illustrated with tabular data. It is shown that a constant MR for life-table calculation of e consistently overestimates projected annual mortality at older attained ages and underestimates e. The EDR method, approved for reserve calculations, is also recommended for use in underwriting conversion tables.

  9. A novel peptide from the ACEI/BPP-CNP precursor in the venom of Crotalus durissus collilineatus.

    PubMed

    Higuchi, Shigesada; Murayama, Nobuhiro; Saguchi, Ken-ichi; Ohi, Hiroaki; Fujita, Yoshiaki; da Silva, Nelson Jorge; de Siqueira, Rodrigo José Bezerra; Lahlou, Saad; Aird, Steven D

    2006-10-01

    In crotaline venoms, angiotensin-converting enzyme inhibitors [ACEIs, also known as bradykinin potentiating peptides (BPPs)], are products of a gene coding for an ACEI/BPP-C-type natriuretic peptide (CNP) precursor. In the genes from Bothrops jararaca and Gloydius blomhoffii, ACEI/BPP sequences are repeated. Sequencing of a cDNA clone from venom glands of Crotalus durissus collilineatus showed that two ACEIs/BPPs are located together at the N-terminus, but without repeats. An additional sequence for CNP was unexpectedly found at the C-terminus. Homologous genes for the ACEI/BPP-CNP precursor suggest that most crotaline venoms contain both ACEIs/BPPs and CNP. The sequence of ACEIs/BPPs is separated from the CNP sequence by a long spacer sequence. Previously, there was no evidence that this spacer actually coded any expressed peptides. Aird and Kaiser (1986, unpublished) previously isolated and sequenced a peptide of 11 residues (TPPAGPDVGPR) from Crotalus viridis viridis venom. In the present study, analysis of the cDNA clone from C. d. collilineatus revealed a nearly identical sequence in the ACEI/BPP-CNP spacer. Fractionation of the crude venom by reverse phase HPLC (C(18)), and analysis of the fractions by mass spectrometry (MS) indicated a component of 1020.5 Da. Amino acid sequencing by MS/MS confirmed that C. d. collilineatus venom contains the peptide TPPAGPDGGPR. Its high proline content and paired proline residues are typical of venom hypotensive peptides, although it lacks the usual N-terminal pyroglutamate. It has no demonstrable hypotensive activity when injected intravenously in rats; however, its occurrence in the venoms of dissimilar species suggests that its presence is not accidental. Evidence suggests that these novel toxins probably activate anaphylatoxin C3a receptors.

  10. Human resource management and performance in healthcare organisations.

    PubMed

    Harris, Claire; Cortvriend, Penny; Hyde, Paula

    2007-01-01

    The purpose of this paper is to compare the evidence from a range of reviews concerned with the links between human resource management (HRM) and performance. The aim of the paper is to review this diverse literature, and to derive human resource (HR) implications for healthcare researchers, policy makers and managers. Recent reviews of the human resource management and performance literature are examined, in addition to the inclusion of a previously unpublished review. Their methods, HRM focus, findings and recommendations are contrasted in order to produce this review. The paper finds that relationships have been found between a range of HRM practices, policies systems and performance. Despite being an important concern for HR professionals, there is little research exploring the link between HRM and performance in the health sector. The paper sees that recent studies have found HRM practices to be associated with patient outcomes such as mortality, yet they yield little information regarding the processes through which HRM affects individual performance and its consequent impact on patient care. The use of approaches that seek to gain an understanding of workers' interpretations of their experience, i.e. the psychological process through which HRM can affect individual performance, may shed some light on how these processes work in practice. The paper shows that increasing autonomy for healthcare organisations in the UK, i.e. Foundation Trusts, may offer increased opportunity for locally tailored HR systems and practices. The paper presents findings drawn from a review of previous research on a subject of increasing relevance to HR researchers and practitioners in healthcare organisations. The paper indicates alternative approaches to research and practice in light of extant research.

  11. Exploratory factor analysis of the Clinical Learning Environment, Supervision and Nurse Teacher Scale (CLES+T).

    PubMed

    Watson, Paul Barry; Seaton, Philippa; Sims, Deborah; Jamieson, Isabel; Mountier, Jane; Whittle, Rose; Saarikoski, Mikko

    2014-01-01

    The Clinical Learning Environment, Supervision and Nurse Teacher (CLES+T) scale measures student nurses' perceptions of clinical learning environments. This study evaluates the construct validity and internal reliability of the CLES+T in hospital settings in New Zealand. Comparisons are made between New Zealand and Finnish data. The CLES+T scale was completed by 416 Bachelor of Nursing students following hospital clinical placements between October 2008 and December 2009. Construct validity and internal reliability were assessed using exploratory factor analysis and Cronbach's alpha. Exploratory factor analysis supports 4 factors. Cronbach's alpha ranged from .82 to .93. All items except 1 loaded on the same factors found in unpublished Finnish data. The first factor combined 2 previous components from the published Finnish component analysis and was renamed: connecting with, and learning in, communities of clinical practice. The remaining 3 factors (Nurse teacher, Supervisory relationship, and Leadership style of the manager) corresponded to previous components and their conceptualizations. The CLES+T has good internal reliability and a consistent factor structure across samples. The consistency across international samples supports faculties and hospitals using the CLES+T to benchmark the quality of clinical learning environments provided to students.

  12. Clinical Trial Updates and Hotline Sessions presented at the European Society of Cardiology Congress 2007: (FINESSE, CARESS, OASIS 5, PRAGUE-8, OPTIMIST, GRACE, STEEPLE, SCAAR, STRATEGY, DANAMI-2, ExTRACT-TIMI-25, ISAR-REACT 2, ACUITY, ALOFT, 3CPO, PROSPECT, EVEREST, COACH, BENEFiT, MERLIN-TIMI 36, SEARCH-MI, ADVANCE, WENBIT, EUROASPIRE I-III, ARISE, getABI, RIO).

    PubMed

    Kindermann, Michael; Adam, Oliver; Werner, Nikos; Böhm, Michael

    2007-11-01

    This article provides information and commentaries on trials which were presented at the Hotline and Clinical Trial Update Sessions at the European Society of Cardiology Congress 2007 in Vienna. The key presentations were performed by leading experts in the field with relevant positions in the trials or registries. It is important to note that unpublished reports should be considered as preliminary data, as the analysis may change in the final publications. The comprehensive summaries have been generated from the oral presentation and the webcasts of the European Society of Cardiology and should provide the readers with the most comprehensive information of relevant publications.

  13. The second European interdisciplinary Ewing sarcoma research summit – A joint effort to deconstructing the multiple layers of a complex disease

    PubMed Central

    2016-01-01

    Despite multimodal treatment, long term outcome for patients with Ewing sarcoma is still poor. The second “European interdisciplinary Ewing sarcoma research summit” assembled a large group of scientific experts in the field to discuss their latest unpublished findings on the way to the identification of novel therapeutic targets and strategies. Ewing sarcoma is characterized by a quiet genome with presence of an EWSR1-ETS gene rearrangement as the only and defining genetic aberration. RNA-sequencing of recently described Ewing-like sarcomas with variant translocations identified them as biologically distinct diseases. Various presentations adressed mechanisms of EWS-ETS fusion protein activities with a focus on EWS-FLI1. Data were presented shedding light on the molecular underpinnings of genetic permissiveness to this disease uncovering interaction of EWS-FLI1 with recently discovered susceptibility loci. Epigenetic context as a consequence of the interaction between the oncoprotein, cell type, developmental stage, and tissue microenvironment emerged as dominant theme in the discussion of the molecular pathogenesis and inter- and intra-tumor heterogeneity of Ewing sarcoma, and the difficulty to generate animal models faithfully recapitulating the human disease. The problem of preclinical development of biologically targeted therapeutics was discussed and promising perspectives were offered from the study of novel in vitro models. Finally, it was concluded that in order to facilitate rapid pre-clinical and clinical development of novel therapies in Ewing sarcoma, the community needs a platform to maintain knowledge of unpublished results, systems and models used in drug testing and to continue the open dialogue initiated at the first two Ewing sarcoma summits. PMID:26802024

  14. The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex disease.

    PubMed

    Kovar, Heinrich; Amatruda, James; Brunet, Erika; Burdach, Stefan; Cidre-Aranaz, Florencia; de Alava, Enrique; Dirksen, Uta; van der Ent, Wietske; Grohar, Patrick; Grünewald, Thomas G P; Helman, Lee; Houghton, Peter; Iljin, Kristiina; Korsching, Eberhard; Ladanyi, Marc; Lawlor, Elizabeth; Lessnick, Stephen; Ludwig, Joseph; Meltzer, Paul; Metzler, Markus; Mora, Jaume; Moriggl, Richard; Nakamura, Takuro; Papamarkou, Theodore; Radic Sarikas, Branka; Rédini, Francoise; Richter, Guenther H S; Rossig, Claudia; Schadler, Keri; Schäfer, Beat W; Scotlandi, Katia; Sheffield, Nathan C; Shelat, Anang; Snaar-Jagalska, Ewa; Sorensen, Poul; Stegmaier, Kimberly; Stewart, Elizabeth; Sweet-Cordero, Alejandro; Szuhai, Karoly; Tirado, Oscar M; Tirode, Franck; Toretsky, Jeffrey; Tsafou, Kalliopi; Üren, Aykut; Zinovyev, Andrei; Delattre, Olivier

    2016-02-23

    Despite multimodal treatment, long term outcome for patients with Ewing sarcoma is still poor. The second "European interdisciplinary Ewing sarcoma research summit" assembled a large group of scientific experts in the field to discuss their latest unpublished findings on the way to the identification of novel therapeutic targets and strategies. Ewing sarcoma is characterized by a quiet genome with presence of an EWSR1-ETS gene rearrangement as the only and defining genetic aberration. RNA-sequencing of recently described Ewing-like sarcomas with variant translocations identified them as biologically distinct diseases. Various presentations adressed mechanisms of EWS-ETS fusion protein activities with a focus on EWS-FLI1. Data were presented shedding light on the molecular underpinnings of genetic permissiveness to this disease uncovering interaction of EWS-FLI1 with recently discovered susceptibility loci. Epigenetic context as a consequence of the interaction between the oncoprotein, cell type, developmental stage, and tissue microenvironment emerged as dominant theme in the discussion of the molecular pathogenesis and inter- and intra-tumor heterogeneity of Ewing sarcoma, and the difficulty to generate animal models faithfully recapitulating the human disease. The problem of preclinical development of biologically targeted therapeutics was discussed and promising perspectives were offered from the study of novel in vitro models. Finally, it was concluded that in order to facilitate rapid pre-clinical and clinical development of novel therapies in Ewing sarcoma, the community needs a platform to maintain knowledge of unpublished results, systems and models used in drug testing and to continue the open dialogue initiated at the first two Ewing sarcoma summits.

  15. A 320-year long series of Danube floods in Central Hungary (Budapest and Pest County): a frequency-magnitude-seasonality overview

    NASA Astrophysics Data System (ADS)

    Kiss, Andrea; Salinas, Jose; Bloeschl, Guenter

    2015-04-01

    The present paper is based on a recently developed database including contemporary original, administrative, legal and private source materials (published and archival) as well as media reports related to the floods occurred in the town of Budapest (historical towns of Pest, Buda) and Central Hungary (historical Pest-Pilis-Solt County). As for the archival evidence, main bases of investigation are the administrative sources such as town council protocols and county meeting protocols of Budapest and historical Pest-Pilis-Solt County: in these (legal-)administrative documents damaging events (natural/environmental hazards) were systematically recorded. Moreover, other source types such as taxation-related damage accounts as well as private and official reports, letters and correspondence (published, unpublished) were also included. Concerning published evidence, a most important source is flood reports in contemporary newspapers; however, other published sources (e.g. narratives, fund raising circulars etc.; both published and unpublished) also contained useful flood-related information. Beyond providing information on the strength and weaknesses of different sources types and the temporal and spatial distribution of evidence, a general background on the contemporary environmental and hydrological/hydromorphological conditions of the study area (and its changes during and after river regulations) are also provided. However, in the presentation the main focus is on the analysis of flood rich flood poor periods of the last more than 300 years; furthermore, the seasonality distribution as well as the magnitude of Danube flood events - and their spatial differences are discussed. In case of Budapest and Central Hungary, with respect to the greatest flood events, ice jam floods played a rather significant role before river regulation works. Due to this fact the main types of flood events (including their main causes), with special emphasis on ice jam floods, are discussed separate.

  16. Studies of educational interventions and outcomes in diabetic adults: a meta-analysis revisited.

    PubMed

    Brown, S A

    1990-12-01

    This paper reports a follow-up of previous meta-analysis research conducted by the author on the effects of diabetes patient education on patient outcomes. An expanded sample of studies and psychological outcome variables were added to the previously studied variables of patient knowledge, self-care behaviors (compliance and skill performance) and metabolic control. The purpose was to determine: (1) the effects of patient education on specific outcome variables; and (2) the relationships between effects of education and characteristics of the studies and/or subjects. Following an extensive literature search, a total of 82 studies were found which met the inclusion criteria for this analysis; 68% were published and 32% were unpublished. Homogeneity analyses of specific patient outcome variables yielded the following results: knowledge effects ranged from 0.49 to 1.05; self-care behavior effects from 0.17 to 0.57, with insulin injection and weight loss associated with the smallest effect sizes; metabolic control from 0.16 to 0.41; and psychological outcomes 0.27. Mean age of the subjects was negatively correlated with knowledge and cholesterol, indicating that the older the mean age of the subjects, the lower the effects of patient education on these variables. Findings of this meta-analysis on the expanded data set were consistent with the previous meta-analysis and lend support to the effectiveness of diabetes patient education in improving patient outcomes.

  17. Animal models of human immunodeficiency virus infection. Public Health Service Animal Models Committee.

    PubMed

    Spertzel, R O

    1989-12-01

    The search for a model of HIV infection continues. While much of the initial work focussed on animal models of AIDS, more recent efforts have sought animal models of HIV infection in which one or more signs of AIDS may be reproduced. Most initial small animal modelling efforts were negative and many such efforts remain unpublished. In 1988, the Public Health Service (PHS) AIDS Animal Model Committee conducted a survey among PHS agencies to identify published and unpublished data on animal models of HIV. To date, the chimpanzee is the only animal to be reliably infected with HIV albeit without development of signs and symptoms normally associated with human AIDS. One recent study has shown the gibbon to be similarly susceptible to infection with HIV. Mice carrying a chimera of elements of the human immune system have been shown to support the growth of HIV and F1 progeny of transgenic mice containing intact copies of HIV proviral DNA, have developed a disease that resembles some aspects of human AIDS. Rabbits, baboons and rhesus monkeys have also been shown to be infected under certain conditions and/or with selected strains of HIV but again without the development of AIDS symptomatology. This report briefly summarizes published and available unpublished data on these efforts to develop an animal model of HIV infection.

  18. Using semantics for representing experimental protocols.

    PubMed

    Giraldo, Olga; García, Alexander; López, Federico; Corcho, Oscar

    2017-11-13

    An experimental protocol is a sequence of tasks and operations executed to perform experimental research in biological and biomedical areas, e.g. biology, genetics, immunology, neurosciences, virology. Protocols often include references to equipment, reagents, descriptions of critical steps, troubleshooting and tips, as well as any other information that researchers deem important for facilitating the reusability of the protocol. Although experimental protocols are central to reproducibility, the descriptions are often cursory. There is the need for a unified framework with respect to the syntactic structure and the semantics for representing experimental protocols. In this paper we present "SMART Protocols ontology", an ontology for representing experimental protocols. Our ontology represents the protocol as a workflow with domain specific knowledge embedded within a document. We also present the S ample I nstrument R eagent O bjective (SIRO) model, which represents the minimal common information shared across experimental protocols. SIRO was conceived in the same realm as the Patient Intervention Comparison Outcome (PICO) model that supports search, retrieval and classification purposes in evidence based medicine. We evaluate our approach against a set of competency questions modeled as SPARQL queries and processed against a set of published and unpublished protocols modeled with the SP Ontology and the SIRO model. Our approach makes it possible to answer queries such as Which protocols use tumor tissue as a sample. Improving reporting structures for experimental protocols requires collective efforts from authors, peer reviewers, editors and funding bodies. The SP Ontology is a contribution towards this goal. We build upon previous experiences and bringing together the view of researchers managing protocols in their laboratory work. Website: https://smartprotocols.github.io/ .

  19. Toward an architecture of attachment disorganization: John Bowlby’s published and unpublished reflections

    PubMed Central

    Solomon, Judith; Duschinsky, Robbie; Bakkum, Lianne; Schuengel, Carlo

    2017-01-01

    This article examines the construct of disorganized attachment originally proposed by Main and Solomon, developing some new conjectures based on inspiration from a largely unknown source: John Bowlby’s unpublished texts, housed at the Wellcome Trust Library Archive in London (with permission from the Bowlby family). We explore Bowlby’s discussions of disorganized attachment, which he understood from the perspective of ethological theories of conflict behavior. Bowlby’s reflections regarding differences among the behaviors used to code disorganized attachment will be used to explore distinctions that may underlie the structure of the current coding system. The article closes with an emphasis on the importance Bowlby placed on Popper’s distinction between the context of discovery and the context of justification in developmental science. PMID:28791871

  20. Quantum gravity: yesterday and today

    NASA Astrophysics Data System (ADS)

    Dewitt, Bryce

    2009-02-01

    Bryce DeWitt was one of the great pioneers of quantum gravity. This unpublished lecture gives his recent views on the topic, which we believe will be of great interest not only to researchers involved in modern attempts to quantize Einstein’s theory, but also to a much wider audience. It is the first installment of a book “The Pursuit of Quantum Gravity 1946-2004; Memoirs of Bryce DeWitt” that Cecile DeWitt is preparing. We would like to thank her for the permission to publish this lecture separately in General Relativity and Gravitation. Readers who have unpublished material such as letters from Bryce, and would be willing to send copies to Cecile, are hereby invited to do so. She would be very grateful. G.F.R. Ellis, H. Nicolai (Editors-in-chief).

  1. Beta decay of 187Re and cosmochronology

    NASA Astrophysics Data System (ADS)

    Ashktorab, K.; Jänecke, J. W.; Becchetti, F. D.

    1993-06-01

    Uncertainties which limit the use of the 187-187Os isobaric pair as a cosmochronometer for the age of the galaxy and the universe include those of the partial half-lives of the continuum and bound-state decays of 187Re. While the total half-life of the decay is well established, the partial half-life for the continuum decay is uncertain, and several previous measurements are not compatible with each other. A high-temperature quartz proportional counter has been used in this work to remeasure the continuum decay of 187Re by introducing a metallo-organic rhenium compound into the counting gas. The measured beta end-point energy for the continuum decay of neutral 187Re to singly ionized 187Os of 2.70+/-0.09 keV agrees with earlier results. However, the present half-life measurement of (45+/-3) Gyr agrees within the quoted uncertainties only with the earlier measurement of Payne [Ph.D. thesis, University of Glasgow, 1965 (unpublished)] and Drever (private communication). The new half-life for the continuum decay and the total half-life of (43.5+/-1.3) Gyr, as reported by Linder et al. [Nature (London) 320, 246 (1986)] yield a branching ratio for the bound-state decay into discrete atomic states of (3+/-6)%. This is in agreement with the most recent calculated theoretical branching ratio of approximately 1%.

  2. Rare events in earth history include the LB1 human skeleton from Flores, Indonesia, as a developmental singularity, not a unique taxon

    NASA Astrophysics Data System (ADS)

    Eckhardt, Robert B.; Henneberg, Maciej; Weller, Alex S.; Hsü, Kenneth J.

    2014-08-01

    The original centrally defining features of "Homo floresiensis" are based on bones represented only in the single specimen LB1. Initial published values of 380-mL endocranial volume and 1.06-m stature are markedly lower than later attempts to confirm them, and facial asymmetry originally unreported, then denied, has been established by our group and later confirmed independently. Of nearly 200 syndromes in which microcephaly is one sign, more than half include asymmetry as another sign and more than one-fourth also explicitly include short stature. The original diagnosis of the putative new species noted and dismissed just three developmental abnormalities. Subsequent independent attempts at diagnosis (Laron Syndrome, Majewski osteodysplastic primordial dwarfism type II, cretinism) have been hampered a priori by selectively restricted access to specimens, and disparaged a posteriori using data previously unpublished, without acknowledging that all of the independent diagnoses corroborate the patent abnormal singularity of LB1. In this report we establish in detail that even in the absence of a particular syndromic diagnosis, the originally defining features of LB1 do not establish either the uniqueness or normality necessary to meet the formal criteria for a type specimen of a new species. In a companion paper we present a new syndromic diagnosis for LB1.

  3. Treacher Collins syndrome: clinical implications for the paediatrician--a new mutation in a severely affected newborn and comparison with three further patients with the same mutation, and review of the literature.

    PubMed

    Schlump, Jan-Ulrich; Stein, Anja; Hehr, Ute; Karen, Tanja; Möller-Hartmann, Claudia; Elcioglu, Nursel H; Bogdanova, Nadja; Woike, Hartmut Fritz; Lohmann, Dietmar R; Felderhoff-Mueser, Ursula; Linz, Annette; Wieczorek, Dagmar

    2012-11-01

    Treacher Collins syndrome (TCS) is the most common and well-known mandibulofacial dysostosis caused by mutations in at least three genes involved in pre-rRNA transcription, the TCOF1, POLR1D and POLR1C genes. We present a severely affected male individual with TCS with a heterozygous de novo frameshift mutation within the TCOF1 gene (c.790_791delAG,p.Ser264GlnfsX7) and compare the clinical findings with three previously unpublished, milder affected individuals from two families with the same mutation. We elucidate typical clinical features of TCS and its clinical implications for the paediatrician and mandibulofacial surgeon, especially in severely affected individuals and give a short review of the literature. The clinical data of these three families illustrate that the phenotype associated with this specific mutation has a wide intra- and interfamilial variability, which confirms that variable expressivity in carriers of TCOF1 mutations is not a simple consequence of the mutation but might be modified by the combination of genetic, environmental and stochastic factors. Being such a highly complex disease treatment of individuals with TCS should be tailored to the specific needs of each individual, preferably by a multidisciplinary team consisting of paediatricians, craniofacial surgeons and geneticists.

  4. Connectivity of precuneus to the default mode and dorsal attention networks: A possible invariant marker of long-term tinnitus.

    PubMed

    Schmidt, Sara A; Carpenter-Thompson, Jake; Husain, Fatima T

    2017-01-01

    Resting state functional connectivity studies of tinnitus have provided inconsistent evidence concerning its neural bases. This may be due to differences in the methodology used, but it is also likely related to the heterogeneity of the tinnitus population. In this study, our goal was to identify resting state functional connectivity alterations that consistently appear across tinnitus subgroups. We examined two sources of variability in the subgroups: tinnitus severity and the length of time a person has had chronic tinnitus (referred to as tinnitus duration). Data for the current large-scale analysis of variance originated partly from our earlier investigations (Schmidt et al., 2013; Carpenter-Thompson et al., 2015) and partly from previously unpublished studies. Decreased correlations between seed regions in the default mode network and the precuneus were consistent across individuals with long-term tinnitus (who have had tinnitus for greater than one year), with more bothersome tinnitus demonstrating stronger decreases. In the dorsal attention network, patients with moderately severe tinnitus showed increased correlations between seeds in the network and the precuneus, with this effect also present in only some patients with mild tinnitus. The same effects were not seen in patients with mild tinnitus and tinnitus duration between 6 and 12 months. Our results are promising initial steps towards identifying invariant neural correlates of tinnitus and indexing differences between subgroups.

  5. Compendium of Experimental Cetane Numbers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yanowitz, J.; Ratcliff, M. A.; McCormick, R. L.

    This report is an updated version of the 2004 Compendium of Experimental Cetane Number Data and presents a compilation of measured cetane numbers for pure chemical compounds. It includes all available single compound cetane number data found in the scientific literature up until March 2014 as well as a number of unpublished values, most measured over the past decade at the National Renewable Energy Laboratory. This Compendium contains cetane values for 389 pure compounds, including 189 hydrocarbons and 201 oxygenates. More than 250 individual measurements are new to this version of the Compendium. For many compounds, numerous measurements are included,more » often collected by different researchers using different methods. Cetane number is a relative ranking of a fuel's autoignition characteristics for use in compression ignition engines; it is based on the amount of time between fuel injection and ignition, also known as ignition delay. The cetane number is typically measured either in a single-cylinder engine or a constant volume combustion chamber. Values in the previous Compendium derived from octane numbers have been removed, and replaced with a brief analysis of the correlation between cetane numbers and octane numbers. The discussion on the accuracy and precision of the most commonly used methods for measuring cetane has been expanded and the data has been annotated extensively to provide additional information that will help the reader judge the relative reliability of individual results.« less

  6. A systematic review of etiological and risk factors associated with bruxism.

    PubMed

    Feu, Daniela; Catharino, Fernanda; Quintão, Catia Cardoso Abdo; Almeida, Marco Antonio de Oliveira

    2013-06-01

    The aim of the present work was to systematically review the literature and identify all peer-reviewed papers dealing with etiological and risk factors associated with bruxism. Data extraction was carried out according to the standard Cochrane systematic review methodology. The following databases were searched for randomized clinical trials (RCT), controlled clinical trials (CCT) or cohort studies: Cochrane Library, Medline, and Embase from 1980 to 2011. Unpublished literature was searched electronically using ClinicalTrials.gov. The primary outcome was bruxism etiology. Studies should have a standardized method to assess bruxism. Screening of eligible studies, assessment of the methodological quality and data extraction were conducted independently and in duplicate. Two reviewers inspected the references using the same search strategy and then applied the same inclusion criteria to the selected studies. They used criteria for methodological quality that was previously described in the Cochrane Handbook. Among the 1247 related articles that were critically assessed, one randomized clinical trial, one controlled clinical trial and seven longitudinal studies were included in the critical appraisal. Of these studies, five were selected, but reported different outcomes. There is convincing evidence that (sleep-related) bruxism can be induced by esophageal acidification and also that it has an important relationship with smoking in a dose-dependent manner. Disturbances in the central dopaminergic system are also implicated in the etiology of bruxism.

  7. New Zealand women living with HIV/AIDS: a feminist perspective.

    PubMed

    Bennett, Jill

    2007-07-01

    This paper draws on current and earlier literature, together with observational and anecdotal data to reveal the situation of HIV positive women in New Zealand. The present picture is examined in relation to data from a previously unpublished qualitative study undertaken by the author in 2001 using a feminist perspective. It would seem that dominant concerns of the women today are much the same as those surfacing in the earlier study. These include stigma and the associated problem of whether to conceal or reveal. Additionally these women are concerned that health professionals do not always take their problems seriously. Their distress is aggravated by fact of them being women suffering from what is generally seen as a male disease. The feminist perspective highlights the relative powerlessness of many women in the context of sexual relations whereby much of the prophylactic advice--such as insistence on condom use--becomes irrelevant. New women oriented education programmes are needed. It is argued that nurses are well placed to make a positive contribution in this area of care, and in fact are obligated to do so if their practice is to be consistent with the profession's declared aims with respect to cultural safety. However it is noted that there is still a degree of prejudice and ignorance to be overcome before the desired results will be achieved.

  8. Improving geomagnetic observatory data in the South Atlantic Anomaly

    NASA Astrophysics Data System (ADS)

    Matzka, Jürgen; Morschhauser, Achim; Brando Soares, Gabriel; Pinheiro, Katia

    2016-04-01

    The Swarm mission clearly proofs the benefit of coordinated geomagnetic measurements from a well-tailored constellation in order to recover as good as possible the contributions of the various geomagnetic field sources. A similar truth applies to geomagnetic observatories. Their scientific value can be maximised by properly arranging the position of individual observatories with respect to the geometry of the external current systems in the ionosphere and magnetosphere, with respect to regions of particular interest for secular variation, and with respect to regions of anomalous electric conductivity in the ground. Here, we report on our plans and recent efforts to upgrade geomagnetic observatories and to recover unpublished data from geomagnetic observatories at low latitudes in the South Atlantic Anomaly. In particular, we target the magnetic equator with the equatorial electrojet and low latitudes to characterise the Sq- and ring current. The observatory network that we present allows also to study the longitudinal structure of these external current systems. The South Atlantic Anomaly region is very interesting due to its secular variation. We will show newly recovered data and comparisons with existing data sets. On the technical side, we introduce low-power data loggers. In addition, we use mobile phone data transfer, which is rapidly evolving in the region and allows timely data access and quality control at remote sites that previously were not connected to the internet.

  9. The early relationship between Sigmund Freud and Isidor Sadger: a dream (1897) and a letter (1902).

    PubMed

    May, Ulrike

    2003-01-01

    Proceeding from Wittels' comment that Isidor Sadger's essay "The miracle of the thinking protein" (1897a) was the day residue for Freud's dream of the norekdal style, I suggest that the dream was dreamt between February/April 1897 and autumn 1897. I go on to consider which of Sadger's publications on Ibsen could have been the second day residue for Freud's dream. Against the background of Freud and Sadger's relationship in the 1890s, I examine what it was about Sadger's essay that could have precipitated the dream. Flechsig's basic conception of the connection between brain and mind and Sadger's pre-analytical view of psychic phenomena are outlined. Furthermore, a previously unpublished letter from Freud to Sadger in 1902 is presented and its possible context discussed. I show that Sadger probably already began carrying out analyses in 1898 and that, of Freud's immediate circle in Vienna, he was either the first or the second doctor to begin analytical work. In addition Sadger already made references to Freud in his publications in 1897. In summary, Isidor Sadger was probably the only one of Freud's disciples for whom the following combination was true: he became interested in Freud's approach before 1900, carried out analyses before 1900, publicly spoke out for Freud before 1900, became a member of the Wednesday group and stayed in Freud's vicinity for a long time (until 1933).

  10. Attenuation of sinking particulate organic carbon flux through the mesopelagic ocean

    PubMed Central

    Marsay, Chris M.; Sanders, Richard J.; Henson, Stephanie A.; Pabortsava, Katsiaryna; Achterberg, Eric P.; Lampitt, Richard S.

    2015-01-01

    The biological carbon pump, which transports particulate organic carbon (POC) from the surface to the deep ocean, plays an important role in regulating atmospheric carbon dioxide (CO2) concentrations. We know very little about geographical variability in the remineralization depth of this sinking material and less about what controls such variability. Here we present previously unpublished profiles of mesopelagic POC flux derived from neutrally buoyant sediment traps deployed in the North Atlantic, from which we calculate the remineralization length scale for each site. Combining these results with corresponding data from the North Pacific, we show that the observed variability in attenuation of vertical POC flux can largely be explained by temperature, with shallower remineralization occurring in warmer waters. This is seemingly inconsistent with conclusions drawn from earlier analyses of deep-sea sediment trap and export flux data, which suggest lowest transfer efficiency at high latitudes. However, the two patterns can be reconciled by considering relatively intense remineralization of a labile fraction of material in warm waters, followed by efficient downward transfer of the remaining refractory fraction, while in cold environments, a larger labile fraction undergoes slower remineralization that continues over a longer length scale. Based on the observed relationship, future increases in ocean temperature will likely lead to shallower remineralization of POC and hence reduced storage of CO2 by the ocean. PMID:25561526

  11. High spectral resolution observations of HNC3 and HCCNC in the L1544 pre-stellar core

    NASA Astrophysics Data System (ADS)

    Vastel, C.; Kawaguchi, K.; Quénard, D.; Ohishi, M.; Lefloch, B.; Bachiller, R.; Müller, H. S. P.

    2018-02-01

    HCCNC and HNC3 are less commonly found isomers of cyanoacetylene, HC3N, a molecule that is widely found in diverse astronomical sources. We want to know if HNC3 is present in sources other than the dark cloud TMC-1 and how its abundance is relative to that of related molecules. We used the Astrochemical Studies At IRAM unbiased spectral survey at IRAM 30 m towards the prototypical pre-stellar core L1544 to search for HNC3 and HCCNC which are by-product of the HC3NH+ recombination, previously detected in this source. We performed a combined analysis of published HNC3 microwave rest frequencies with thus far unpublished millimetre data because of issues with available rest frequency predictions. We determined new spectroscopic parameters for HNC3, produced new predictions and detected it towards L1544. We used a gas-grain chemical modelling to predict the abundances of N-species and compare with the observations. The modelled abundances are consistent with the observations, considering a late stage of the evolution of the pre-stellar core. However, the calculated abundance of HNC3 was found 5-10 times higher than the observed one. The HC3N, HNC3, and HCCNC versus HC3NH+ ratios are compared in the TMC-1 dark cloud and the L1544 pre-stellar core.

  12. [The "conclusions of Pharmacy" in Nancy, at the end of the 18th century: between "synthèses" and "thèses"].

    PubMed

    Julien, P; Martin, J

    1995-01-01

    A special requirement of the law for apothecaries in Nancy in 1764 imposed on the candidates for a master's degree was the written response to four questions following their practical examinations. Two documents heretofore unpublished show the results of this obligation: the Conclusions de Pharmacie by Joseph Pierson (1765) and the Conclusions de Pharmacie et de Chimie by François Mandel (1771). The authors of the present article comment on these documents and make an attempt to place them in the confused history of "synthèses" and "thèses".

  13. Dataset on records of Hericium erinaceus in Slovakia.

    PubMed

    Kunca, Vladimír; Čiliak, Marek

    2017-06-01

    The data presented in this article are related to the research article entitled "Habitat preferences of Hericium erinaceus in Slovakia" (Kunca and Čiliak, 2016) [FUNECO607] [2]. The dataset include all available and unpublished data from Slovakia, besides the records from the same tree or stem. We compiled a database of records of collections by processing data from herbaria, personal records and communication with mycological activists. Data on altitude, tree species, host tree vital status, host tree position and intensity of management of forest stands were evaluated in this study. All surveys were based on basidioma occurrence and some result from targeted searches.

  14. Factors limiting the recovery of boreal toads (Bufo b. boreas)

    USGS Publications Warehouse

    Carey, C.; Corn, P.S.; Jones, M.S.; Livo, L.J.; Muths, E.; Loeffler, C.W.; Lannoo, M.

    2005-01-01

    Boreal toads (Bufo b. boreas) are widely distributed over much of the mountainous western United States. Populations in the Southern Rocky Mountains suffered extensive declines in the late 1970s through early 1980s (Carey, 1993). At the time, these mass mortalities were thought to be associated with a bacterial infection (Carey, 1993). Although the few populations that survived the mass die-offs were not systematically monitored until at least 1993, no mass mortalities had been observed until 1996 when die-offs were observed. A mycotic skin infection associated with a chytrid fungus is now causing mortality of toads in at least two of the populations (M.S. Jones and D.E. Green, unpublished data; Muths et al., 2003). Boreal toads are now absent throughout large areas of their former distribution in Colorado and southern Wyoming and may be extinct in New Mexico (Corn et al., 1989; Carey, 1993; Stuart and Painter, 1994). These toads are classified as “endangered” by Colorado and New Mexico and are designated as a protected non-game species in Wyoming. The U.S. Fish and Wildlife Service has categorized the Southern Rocky Mountain populations for federal listing and is currently reviewing their designation as a “warranted but precluded” species for possible listing in the next few years. For the management of boreal toads and their habitats, a Boreal Toad Recovery Team was formed by the Colorado Division of Wildlife in 1995 as part of a collaborative effort with federal agencies within the United States’ departments of the Interior and Agriculture and with agencies in two adjoining states. To date, conservation agreements have been signed by eight state and federal agencies and by the Colorado Natural Heritage Program. Although boreal toads were considered common throughout their range in Colorado, no comprehensive surveys of the numbers and sizes of their populations were conducted prior to mass die-offs in the 1970s. Surveys completed in the late 1980s to early 1990s, however, indicated that the toads were still present in only one of 377 historical sites in parts of western Colorado (Hammerson, 1992) and in about 17% of previously known sites in the Colorado Front Range (Corn et al., 1989). Once common in Rocky Mountain National Park, boreal toads are now found at only seven localities, with just two or three of these populations likely to be reproducing successfully each year (Corn et al., 1997). Intensive surveys by the Boreal Toad Recovery Team since 1995 have found about 50 breeding sites comprising 25 distinct populations within Colorado (Loeffler, unpublished data). Of these populations, most are small (fewer than five egg clutches laid per year) and may not survive over the long term. Efforts to restore population sizes and expand the geographical distribution of boreal toads in the southern Rocky Mountains have involved considerable person-hours and financial commitments. Special care has been taken to protect habitats and, when feasible, to improve sites where breeding populations currently exist. However, initial attempts to repatriate these toads in historic habitats in which boreal toads were present before 1975 have generally proven unsuccessful (Carey, unpublished data; Muths et al., 2003). It is too early to determine if recent repatriations will establish breeding populations (Scherff-Norris, 1999), but these efforts will likely continue. Despite the best human intentions and efforts, the recovery of former population sizes and the historical distribution of boreal toads will greatly depend on its own life history characteristics. However, as we will review in this paper, environmental factors affect many life history attributes in a manner that poses serious obstacles for recovery.

  15. The Klumpke family--memories by Doctor Déjerine, born Augusta Klumpke.

    PubMed

    Bogousslavsky, Julien

    2005-01-01

    In this paper, we present a translation of an unpublished autobiographical document by Augusta Déjerine-Klumpke, reporting her early years before she came to Paris to study medicine, when she was able to become one of the first women in France to hold a hospital position, as an extern and an intern. This American-born girl later married Jules Déjerine, who was to become the second successor to Charcot at La Salpétrière 23 years later. The present document gives a vivid account on the preceding years, and emphasizes the extraordinary dynamism and enthusiasm of a young woman, whose efforts and contributions influenced neurology at the turn of the 20th century, and dramatically changed the role of women in medical careers.

  16. Effects of management practices on grassland birds: Clay-colored Sparrow

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Nenneman, Melvin P.; Euliss, Betty R.

    1998-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  17. Effects of management practices on grassland birds: Western Meadowlark

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Zimmerman, Amy L.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  18. Effects of management practices on grassland birds: Chestnut-collared Longspur

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Nenneman, Melvin P.; Euliss, Betty R.

    1998-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  19. Effects of management practices on grassland birds: Baird's Sparrow

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Nenneman, Melvin P.; Euliss, Betty R.

    1998-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  20. Effects of management practices on grassland birds: Nelson's Sharp-tailed Sparrow

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Rabie, Paul A.; Euliss, Betty R.

    2002-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  1. Effects of management practices on grassland birds: McCown's Longspur

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Rabie, Paul A.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  2. Effects of management practices on grassland birds: Burrowing Owl

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Rabie, Paul A.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  3. Effects of management practices on grassland birds: Long-billed Curlew

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Rabie, Paul A.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  4. Effects of management practices on grassland birds: Upland Sandpiper

    USGS Publications Warehouse

    Dechant, Jill A.; Dinkins, Meghan F.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Parkin, Barry D.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  5. Effects of management practices on grassland birds: Lark Sparrow

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Parkin, Barry D.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  6. Effects of management practices on grassland birds: Horned Lark

    USGS Publications Warehouse

    Dinkins, Meghan F.; Zimmerman, Amy L.; Dechant, Jill A.; Parkin, Barry D.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Euliss, Betty R.

    2000-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  7. Effects of management practices on grassland birds: Willet

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Parkin, Barry D.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  8. Effects of management practices on grassland birds: Sedge Wren

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Parkin, Barry D.; Euliss, Betty R.

    1998-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  9. Effects of management practices on grassland birds: Field Sparrow

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Parkin, Barry D.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  10. Effects of management practices on grassland birds: Bobolink

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Zimmerman, Amy L.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  11. Effects of management practices on grassland birds: Lark Bunting

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Zimmerman, Amy L.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  12. Effects of management practices on grassland birds: Vesper Sparrow

    USGS Publications Warehouse

    Dechant, Jill A.; Dinkins, Meghan F.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Euliss, Betty R.

    2000-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  13. Effects of management practices on grassland birds: Dickcissel

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Zimmerman, Amy L.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  14. Effects of management practices on grassland birds: Ferruginous Hawk

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Zimmerman, Amy L.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  15. Effects of management practices on grassland birds: American Bittern

    USGS Publications Warehouse

    Dechant, Jill A.; Sondreal, Marriah L.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Zimmerman, Amy L.; Euliss, Betty R.

    1999-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  16. Effects of management practices on grassland birds: Swainson's Hawk

    USGS Publications Warehouse

    Dechant, Jill A.; Dinkins, Meghan F.; Johnson, Douglas H.; Igl, Lawrence D.; Goldade, Christopher M.; Euliss, Betty R.

    2000-01-01

    Information on the habitat requirements and effects of habitat management on grassland birds were summarized from information in more than 5,500 published and unpublished papers. A range map is provided to indicate the relative densities of the species in North America, based on Breeding Bird Survey (BBS) data. Although birds frequently are observed outside the breeding range indicated, the maps are intended to show areas where managers might concentrate their attention. It may be ineffectual to manage habitat at a site for a species that rarely occurs in an area. The species account begins with a brief capsule statement, which provides the fundamental components or keys to management for the species. A section on breeding range outlines the current breeding distribution of the species in North America, including areas that could not be mapped using BBS data. The suitable habitat section describes the breeding habitat and occasionally microhabitat characteristics of the species, especially those habitats that occur in the Great Plains. Details on habitat and microhabitat requirements often provide clues to how a species will respond to a particular management practice. A table near the end of the account complements the section on suitable habitat, and lists the specific habitat characteristics for the species by individual studies. A special section on prey habitat is included for those predatory species that have more specific prey requirements. The area requirements section provides details on territory and home range sizes, minimum area requirements, and the effects of patch size, edges, and other landscape and habitat features on abundance and productivity. It may be futile to manage a small block of suitable habitat for a species that has minimum area requirements that are larger than the area being managed. The Brown-headed Cowbird (Molothrus ater) is an obligate brood parasite of many grassland birds. The section on cowbird brood parasitism summarizes rates of cowbird parasitism, host responses to parasitism, and factors that influence parasitism, such as nest concealment and host density. The impact of management depends, in part, upon a species' nesting phenology and biology. The section on breeding-season phenology and site fidelity includes details on spring arrival and fall departure for migratory populations in the Great Plains, peak breeding periods, the tendency to renest after nest failure or success, and the propensity to return to a previous breeding site. The duration and timing of breeding varies among regions and years. Species' response to management summarizes the current knowledge and major findings in the literature on the effects of different management practices on the species. The section on management recommendations complements the previous section and summarizes specific recommendations for habitat management provided in the literature. If management recommendations differ in different portions of the species' breeding range, recommendations are given separately by region. The literature cited contains references to published and unpublished literature on the management effects and habitat requirements of the species. This section is not meant to be a complete bibliography; for a searchable, annotated bibliography of published and unpublished papers dealing with habitat needs of grassland birds and their responses to habitat management, use the Grassland and Wetland Birds Bibliography on the home page of this resource.

  17. Preserving the Science Legacy from the Apollo Missions to the Moon

    NASA Technical Reports Server (NTRS)

    Evans, Cindy; Zeigler, Ryan; Lehnert, Kerstin; Todd, Nancy; Blumenfeld, Erika

    2015-01-01

    Six Apollo missions landed on the Moon from 1969-72, returning to Earth 382 kg of lunar rock, soil, and core samples-among the best documented and preserved samples on Earth that have supported a robust research program for 45 years. From mission planning through sample collection, preliminary examination, and subsequent research, strict protocols and procedures are followed for handling and allocating Apollo subsamples. Even today, 100s of samples are allocated for research each year, building on the science foundation laid down by the early Apollo sample studies and combining new data from today's instrumentation, lunar remote sensing missions and lunar meteorites. Today's research includes advances in our understanding of lunar volatiles, lunar formation and evolution, and the origin of evolved lunar lithologies. Much sample information is available to researchers at curator.jsc.nasa.gov. Decades of analyses on lunar samples are published in LPSC proceedings volumes and other peer-reviewed journals, and tabulated in lunar sample compendia entries. However, for much of the 1969-1995 period, the processing documentation, individual and consortia analyses, and unpublished results exist only in analog forms or primitive digital formats that are either inaccessible or at risk of being lost forever because critical data from early investigators remain unpublished. We have initiated several new efforts to rescue some of the early Apollo data, including unpublished analytical data. We are scanning NASA documentation that is related to the Apollo missions and sample processing, and we are collaborating with IEDA to establish a geochemical database called Moon DB. To populate this database, we are working with prominent lunar PIs to organize and transcribe years of both published and unpublished data. Other initiatives include micro-CT scanning of complex lunar samples to document their interior structure (e.g. clasts, vesicles); linking high-resolution scans of Apollo film products to samples; and new procedures for systematic high resolution photography of samples before additional processing, enabling detailed 3D reconstructions of the samples. All of these efforts will provide comprehensive access to Apollo samples and support better curation of the samples for decades to come.

  18. Preserving the Science Legacy from the Apollo Missions to the Moon

    NASA Astrophysics Data System (ADS)

    Todd, N. S.; Evans, C. A.; Zeigler, R. A.; Lehnert, K. A.

    2015-12-01

    Six Apollo missions landed on the Moon from 1969-72, returning to Earth 382 kg of lunar rock, soil, and core samples—among the best documented and preserved samples on Earth that have supported a robust research program for 45 years. From mission planning through sample collection, preliminary examination, and subsequent research, strict protocols and procedures are followed for handling and allocating Apollo subsamples. Even today, 100s of samples are allocated for research each year, building on the science foundation laid down by the early Apollo sample studies and combining new data from today's instrumentation, lunar remote sensing missions and lunar meteorites. Today's research includes advances in our understanding of lunar volatiles, lunar formation and evolution, and the origin of evolved lunar lithologies. Much sample information is available to researchers at curator.jsc.nasa.gov. Decades of analyses on lunar samples are published in LPSC proceedings volumes and other peer-reviewed journals, and tabulated in lunar sample compendia entries. However, for much of the 1969-1995 period, the processing documentation, individual and consortia analyses, and unpublished results exist only in analog forms or primitive digital formats that are either inaccessible or at risk of being lost forever because critical data from early investigators remain unpublished. We have initiated several new efforts to rescue some of the early Apollo data, including unpublished analytical data. We are scanning NASA documentation that is related to the Apollo missions and sample processing, and we are collaborating with IEDA to establish a geochemical database called Moon DB. To populate this database, we are working with prominent lunar PIs to organize and transcribe years of both published and unpublished data. Other initiatives include micro-CT scanning of complex lunar samples to document their interior structure (e.g. clasts, vesicles); linking high-resolution scans of Apollo film products to samples; and new procedures for systematic high resolution photography of samples before additional processing, enabling detailed 3D reconstructions of the samples. All of these efforts will provide comprehensive access to Apollo samples and support better curation of the samples for decades to come.

  19. Cost Analysis of Turbine Engine Warranties.

    DTIC Science & Technology

    1982-09-01

    AFIT/SLGR, Wright- Patterson AFB OH, June 1976. AD A030291. Feltus , Dr. Erasmus E., and John P. Turek. "Warranty Modeling." Unpublished research report, unnumbered, Westinghouse Electric Corporation, undated. 177 I

  20. Interagency Testing Committee

    EPA Pesticide Factsheets

    The ITC's web site is a dynamic interactive vehicle that enables industry to electronically submit unpublished data and for the public (including industry) to retrieve these data and other information created or reviewed by the ITC.

  1. Eyewitness accuracy rates in sequential and simultaneous lineup presentations: a meta-analytic comparison.

    PubMed

    Steblay, N; Dysart, J; Fulero, S; Lindsay, R C

    2001-10-01

    Most police lineups use a simultaneous presentation technique in which eyewitnesses view all lineup members at the same time. Lindsay and Wells (R. C. L. Lindsay & G. L. Wells, 1985) devised an alternative procedure, the sequential lineup, in which witnesses view one lineup member at a time and decide whether or not that person is the perpetrator prior to viewing the next lineup member. The present work uses the technique of meta-analysis to compare the accuracy rates of these presentation styles. Twenty-three papers were located (9 published and 14 unpublished), providing 30 tests of the hypothesis and including 4,145 participants. Results showed that identification of perpetrators from target-present lineups occurs at a higher rate from simultaneous than from sequential lineups. However, this difference largely disappears when moderator variables approximating real world conditions are considered. Also, correct rejection rates were significantly higher for sequential than simultaneous lineups and this difference is maintained or increased by greater approximation to real world conditions. Implications of these findings are discussed.

  2. Preliminary Geologic Map of the Lake Mead 30' X 60' Quadrangle, Clark County, Nevada, and Mohave County, Arizona

    USGS Publications Warehouse

    Beard, L.S.; Anderson, R.E.; Block, D.L.; Bohannon, R.G.; Brady, R.J.; Castor, S.B.; Duebendorfer, E.M.; Faulds, J.E.; Felger, T.J.; Howard, K.A.; Kuntz, M.A.; Williams, V.S.

    2007-01-01

    Introduction The geologic map of the Lake Mead 30' x 60' quadrangle was completed for the U.S. Geological Survey's Las Vegas Urban Corridor Project and the National Parks Project, National Cooperative Geologic Mapping Program. Lake Mead, which occupies the northern part of the Lake Mead National Recreation Area (LAME), mostly lies within the Lake Mead quadrangle and provides recreation for about nine million visitors annually. The lake was formed by damming of the Colorado River by Hoover Dam in 1939. The recreation area and surrounding Bureau of Land Management lands face increasing public pressure from rapid urban growth in the Las Vegas area to the west. This report provides baseline earth science information that can be used in future studies of hazards, groundwater resources, mineral and aggregate resources, and of soils and vegetation distribution. The preliminary report presents a geologic map and GIS database of the Lake Mead quadrangle and a description and correlation of map units. The final report will include cross-sections and interpretive text. The geology was compiled from many sources, both published and unpublished, including significant new mapping that was conducted specifically for this compilation. Geochronologic data from published sources, as well as preliminary unpublished 40Ar/39Ar ages that were obtained for this report, have been used to refine the ages of formal Tertiary stratigraphic units and define new informal Tertiary sedimentary and volcanic units.

  3. 21 CFR 814.84 - Reports.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... be reported to FDA under § 814.39(b). (2) Contain a summary and bibliography of the following... bibliography, FDA concludes that the agency needs a copy of the unpublished or published reports, FDA will...

  4. Guide to listing references.

    DOT National Transportation Integrated Search

    2005-01-01

    The introduction of listing references. It introduces the reference of printed sources, CD-ROMs, websites, unpublished papers and program manuals, tapes, or other documentation for models. Meanwhile, it describes some examples to use Chicago Manual o...

  5. 12 CFR 510.5 - Release of unpublished OTS information.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... testimony or informal interview, that was acquired in the course of performing official duties or because of... wish to question the witness beyond the authorized scope should request expanded authorization pursuant...

  6. EAP viewpoint on unpublished data from paediatric clinical trials.

    PubMed

    Schrier, L; Illy, K; Valiulis, A; Wyder, C; Stiris, T

    2018-02-01

    European children and paediatricians rely heavily on the fair, complete and timely publication of data obtained from paediatric randomised controlled trials (RCTs). Selective publication and reporting of paediatric RCTs is common practice. Industry-sponsored trials are more likely to remain unpublished, and take longer to get published compared with trials sponsored by others. However, also academic sponsors contribute to inefficiencies in publishing clinical data. Publication bias violates the ethical obligation that investigators have towards study participants, leads to considerable inefficiencies in research and a waste of financial and human resources, and has the potential to distort evidence for treatment approaches. The European Academy of Paediatrics (EAP) therefore actively supports initiatives that increase the public dissemination of paediatric clinical trial data. The EAP will raise awareness about the guidelines for Good Publication Practice among European paediatricians and subspecialty societies.

  7. Concentrations of the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in sidestream cigarette smoke increase after release into indoor air: results from unpublished tobacco industry research.

    PubMed

    Schick, Suzaynn F; Glantz, Stanton

    2007-08-01

    Research has shown that the toxicity of sidestream cigarette smoke, the primary constituent of secondhand smoke, increases over time. To find potential mechanisms that would explain the increase in sidestream smoke toxicity over time, we analyzed unpublished research reports from Philip Morris Co. using the internal tobacco industry documents now available at the University of California San Francisco Legacy Tobacco Documents Library and other Web sites. Unpublished research from Philip Morris Tobacco Company shows that 4-(methylnitrosamino)-I-(3-pyridyl)-1-butanone (NNK), a highly carcinogenic tobacco-specific nitrosamine, can form in sidestream cigarette smoke after it has been released into ambient air. In experiments done between 1983 and 1997, Philip Morris scientists measured the concentration of NNK in sidestream smoke in a sealed stainless steel test chamber at initial particle concentrations of 24 mg/m(3) over the course of 6 to 18 h. They repeatedly showed that airborne NNK concentrations in sidestream cigarette smoke can increase by 50% to 200% per hour during the first 6 h after cigarettes are extinguished. Two experiments done in a real office showed that NNK concentrations increase for the first 2 h after cigarettes are extinguished. If NNK formation also occurs in the lower smoke concentrations observed in real smoking environments, these results suggest that nitrosation of nicotine and/or nicotine breakdown products in aging secondhand smoke is a significant contributor to nitrosamine exposure in humans.

  8. Mycetoma (Madura Foot) in Israel: Recent Cases and a Systematic Review of the Literature.

    PubMed

    Bitan, Ohad; Wiener-Well, Yonit; Segal, Rina; Schwartz, Eli

    2017-06-01

    AbstractMycetoma is a chronic soft tissue infection caused by fungal or bacterial pathogens, and is endemic in tropical and subtropical regions. Cases in developed countries outside the mycetoma belt are rare and usually imported by immigrants. Sporadic cases have been reported in Israel. Unpublished cases in the participating medical centers are reported. In addition, a systematic review of the literature was performed. All published mycetoma cases diagnosed in Israel were included with relevant variables collected. Twenty-one cases of mycetoma were diagnosed in Israel between 1942 and 2015, including four unpublished cases and 17 published cases. The mean age at diagnosis was 42 years (range 23-73), and 16 of the patients were male. The foot was the primary involved organ. Fifteen patients were immigrants from Yemen, Ethiopia, and Sudan. Five cases were autochthonous. One case was travel related. Among patients who developed symptoms after immigration, the mean time from exposure to symptom onset was 5.6 years (range 1-10 years). The mean time from symptom onset to diagnosis was 6.6 years (range 0.2-35 years). The autochthonous cases demonstrate that Israel is endemic of mycetoma. The immigrant population represents two distinct waves of immigration to Israel in the past century. Two unpublished cases of Ethiopian immigrants are the first reported cases of mycetoma acquired in Ethiopia. The diagnostic and therapeutic challenges along with the epidemiological data emphasize the need of raising the awareness of physicians to this devastating condition even in developed countries.

  9. Niacin therapy and the risk of new-onset diabetes: a meta-analysis of randomised controlled trials.

    PubMed

    Goldie, Christina; Taylor, Allen J; Nguyen, Peter; McCoy, Cody; Zhao, Xue-Qiao; Preiss, David

    2016-02-01

    Previous studies have suggested that niacin treatment raises glucose levels in patients with diabetes and may increase the risk of developing diabetes. We undertook a meta-analysis of published and unpublished data from randomised trials to confirm whether an association exists between niacin and new-onset diabetes. We searched Medline, EMBASE and the Cochrane Central Register of Controlled Trials, from 1975 to 2014, for randomised controlled trials of niacin primarily designed to assess its effects on cardiovascular endpoints and cardiovascular surrogate markers. We included trials with ≥50 non-diabetic participants and average follow-up of ≥24 weeks. Published data were tabulated and unpublished data sought from investigators. We calculated risk ratios (RR) for new-onset diabetes with random-effects meta-analysis. Heterogeneity between trials was assessed using the I(2) statistic. In 11 trials with 26 340 non-diabetic participants, 1371 (725/13 121 assigned niacin; 646/13 219 assigned control) were diagnosed with diabetes during a weighted mean follow-up of 3.6 years. Niacin therapy was associated with a RR of 1.34 (95% CIs 1.21 to 1.49) for new-onset diabetes, with limited heterogeneity between trials (I(2)=0.0%, p=0.87). This equates to one additional case of diabetes per 43 (95% CI 30 to 70) initially non-diabetic individuals who are treated with niacin for 5 years. Results were consistent regardless of whether participants received background statin therapy (p for interaction=0.88) or combined therapy with laropiprant (p for interaction=0.52). Niacin therapy is associated with a moderately increased risk of developing diabetes regardless of background statin or combination laropiprant therapy. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  10. Raton-Clayton Volcanic Field magmatism in the context of the Jemez Lineament

    NASA Astrophysics Data System (ADS)

    Schrader, C. M.; Pontbriand, A.

    2013-12-01

    The Raton-Clayton Volcanic Field (RCVF) was active from 9 Ma to approximately 50 Ka and stretches from Raton, New Mexico in the west to Clayton, New Mexico in the east. The field occurs in the Great Plains at the northeastern end of the Jemez Lineament, a major crustal feature and focus of volcanism that extends southwest to the Colorado Plateau in Arizona and encompasses five other major volcanic fields. Jemez Lineament magmatism is temporally related to Rio Grande Rift magmatism, though it extends NE and SW from the rift itself, and it has been suggested that it represents an ancient crustal suture that serves as a conduit for magmatism occurring beneath the larger region of north and central New Mexico (Magnani et al., 2004, GEOL SOC AM BULL, 116:7/8, pp. 1-6). This study extends our work into the RCVF from prior and ongoing work in the Mount Taylor Volcanic Field, where we identified different mantle sources with varying degrees of subduction alteration and we determined some of the crustal processes that contribute to the diversity of magma chemistry and eruptive styles there (e.g., AGU Fall Meeting, abst. #V43D-2884 and #V43D-2883). In the RCVF, we are analyzing multiple phases by electron microprobe and plagioclase phenocrysts and glomerocrysts by LA-ICPMS for Sr isotopes and trace elements. We are undertaking this investigation with the following goals: (1) to evaluate previous magma mixing and crustal assimilation models for Sierra Grande andesites (Zhu, 1995, unpublished Ph.D. dissertation, Rice University; Hesse, 1999, unpublished M.S. thesis, Northern Arizona University); (2) to evaluate subduction-modified mantle as the source for RCVF basanites (specifically those at Little Grande); and (3) to assess the possible role of deep crustal cumulates in buffering transitional basalts. In the larger context, these data will be used to evaluate the varying degree of subduction-modification and the effect of crustal thickness on magmatism along the Jemez Lineament.

  11. Promoting influenza vaccination: insights from a qualitative meta-analysis of 14 years of influenza-related communications research by U.S. Centers for Disease Control and Prevention (CDC).

    PubMed

    Nowak, Glen J; Sheedy, Kristine; Bursey, Kelli; Smith, Teresa M; Basket, Michelle

    2015-06-04

    A primary mission of the U.S. Centers for Disease Control and Prevention's (CDC) is promoting immunization against seasonal influenza. As with most education efforts, CDC's influenza-related communications are often informed by formative research. A qualitative meta-analysis of 29 unpublished, primarily qualitative CDC-sponsored studies related to flu and flu vaccination knowledge, attitudes and beliefs (KABs). The studies, undertaken between 2000 and 2013, involved focus groups, in-depth interviews, message testing and surveys. Some involved health care professionals, while others involved members of the public, including sub-populations at risk for severe illness. The themes that emerged suggested progress in terms of KABs related to influenza and influenza vaccination, but also the persistence of many barriers to vaccine acceptance. With respect to the public, recurring themes included limited understanding of influenza and immunization recommendations, indications of greater sub-group recognition of the value of flu vaccination, continued resistance to vaccination among many, and overestimation of the effectiveness of non-vaccine measures. Seven cognitive facilitators of vaccination were identified in the studies along with six cognitive barriers. For health care providers, the analysis suggests greater knowledge and more favorable beliefs, but many misperceptions persist and are similar to those held by the public. KABs often differed by type or category of health care provider. The themes identified in this qualitative analysis illustrate the difficulty in changing KABs related to influenza and influenza vaccine, particularly on the scope and scale needed to greatly improve uptake. Even with an influenza pandemic and more vaccine options available, public and some health care provider perceptions and beliefs are difficult and slow to change. This meta-analysis does, however, provide important insights from previously unpublished information that can help those who are promoting influenza vaccination to health care providers, the general public and specific populations within the general population. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Promoting influenza vaccination: Insights from a qualitative meta-analysis of 14 years of influenza-related communications research by U.S. Centers for Disease Control and Prevention (CDC)

    PubMed Central

    Nowak, Glen J.; Sheedy, Kristine; Bursey, Kelli; Smith, Teresa M.; Basket, Michelle

    2018-01-01

    Introduction A primary mission of the U.S. Centers for Disease Control and Prevention's (CDC) is promoting immunization against seasonal influenza. As with most education efforts, CDCs influenza-related communications are often informed by formative research. Methods A qualitative meta-analysis of 29 unpublished, primarily qualitative CDC-sponsored studies related to flu and flu vaccination knowledge, attitudes and beliefs (KABs). The studies, undertaken between 2000 and 2013, involved focus groups, in-depth interviews, message testing and surveys. Some involved health care professionals, while others involved members of the public, including sub-populations at risk for severe illness. Findings The themes that emerged suggested progress in terms of KABs related to influenza and influenza vaccination, but also the persistence of many barriers to vaccine acceptance. With respect to the public, recurring themes included limited understanding of influenza and immunization recommendations, indications of greater sub-group recognition of the value of flu vaccination, continued resistance to vaccination among many, and overestimation of the effectiveness of non-vaccine measures. Seven cognitive facilitators of vaccination were identified in the studies along with six cognitive barriers. For health care providers, the analysis suggests greater knowledge and more favorable beliefs, but many misperceptions persist and are similar to those held by the public. KABs often differed by type or category of health care provider. Conclusions The themes identified in this qualitative analysis illustrate the difficulty in changing KABs related to influenza and influenza vaccine, particularly on the scope and scale needed to greatly improve uptake. Even with an influenza pandemic and more vaccine options available, public and some health care provider perceptions and beliefs are difficult and slow to change. This meta-analysis does, however, provide important insights from previously unpublished information that can help those who are promoting influenza vaccination to health care providers, the general public and specific populations within the general population. PMID:25936726

  13. Sodium channel blockers for cystic fibrosis.

    PubMed

    Burrows, Elinor F; Southern, Kevin W; Noone, Peadar G

    2014-04-09

    People with cystic fibrosis (CF) have increased transport of the salt, sodium across their airway lining. Over-absorption of sodium results in the dehydration of the liquid that lines the airway surface and (along with defective chloride secretion) is a primary defect in people with CF. To determine whether the topical administration of drugs that block sodium transport improves the respiratory condition of people with CF. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Trials Register comprising references identified from comprehensive electronic database searches, handsearching relevant journals and abstract books of conference proceedings. We contacted principal investigators known to work in the field, previous authors and pharmaceutical companies who manufacture ion transport agents for unpublished or follow-up data.Most recent search of the Group's register: 19 December 2013. Published or unpublished randomised controlled trials (RCTs) or quasi-randomised controlled trials of sodium channel blockers compared to placebo or another sodium channel blocker or the same sodium channel blocker at a different dosing regimen. Two authors independently extracted data. Meta-analysis was limited due to differing study designs. Five RCTs, with a total of 226 participants, examining the topical administration of the short-acting sodium channel blocker, amiloride, compared to placebo were identified as eligible for inclusion in the review. In three studies over six months, there was a significant difference found in the difference in relative change in FVC in favour of placebo (weighted mean difference 1.51% (95% confidence interval -2.77 to -0.25), although heterogeneity was evident. A two-week study demonstrated that hypertonic saline with amiloride pre-treatment did not result in a significant improvement in respiratory function or mucus clearance, in contrast to pre-treatment with placebo. There were no significant differences identified in other clinically relevant outcomes. We found no evidence that the topical administration of a short-acting sodium channel blocker improves respiratory condition in people with cystic fibrosis and some limited evidence of deterioration in lung function.

  14. Sodium channel blockers for cystic fibrosis.

    PubMed

    Burrows, Elinor F; Southern, Kevin W; Noone, Peadar G

    2012-03-14

    People with cystic fibrosis (CF) have increased transport of the salt, sodium across their airway lining. Over-absorption of sodium results in the dehydration of the liquid that lines the airway surface and is a primary defect in people with CF. To determine whether the topical administration of drugs that block sodium transport improves the respiratory condition of people with CF. We searched the Cochrane Cystic Fibrosis and Genetic Disorders Group Trials Register comprising references identified from comprehensive electronic database searches, handsearching relevant journals and abstract books of conference proceedings. We contacted principal investigators known to work in the field, previous authors and pharmaceutical companies who manufacture ion transport agents for unpublished or follow-up data.Most recent search of the Group's register: 22nd August 2011. Published or unpublished randomised controlled trials (RCTs) or quasi-randomised controlled trials of sodium channel blockers compared to placebo or another sodium channel blocker or the same sodium channel blocker at a different dosing regimen. Two authors independently extracted data. Meta-analysis was limited due to differing study designs. Five RCTs, with a total of 226 participants, examining the topical administration of the short-acting sodium channel blocker, amiloride, compared to placebo were identified as eligible for inclusion in the review. In three studies over six months, there was a significant difference found in the difference in relative change in FVC in favour of placebo (weighted mean difference 1.51% (95% confidence interval -2.77 to -0.25), although heterogeneity was evident. A two-week study demonstrated that hypertonic saline with amiloride pre-treatment did not result in a significant improvement in respiratory function or mucus clearance, in contrast to pre-treatment with placebo. There were no significant differences identified in other clinically relevant outcomes. We found no evidence that the topical administration of a short-acting sodium channel blocker improves respiratory condition in people with cystic fibrosis and some limited evidence of deterioration in lung function.

  15. Identifying additional studies for a systematic review of retention strategies in randomised controlled trials: making contact with trials units and trial methodologists.

    PubMed

    Brueton, Valerie; Tierney, Jayne F; Stenning, Sally; Rait, Greta

    2017-08-22

    Search strategies for systematic reviews aim to identify all evidence relevant to the research question posed. Reports of methodological research can be difficult to find leading to biased results in systematic reviews of research methodology. Evidence suggests that contact with investigators can help to identify unpublished research. To identify additional eligible randomised controlled trials (RCTs) for a Cochrane systematic review of strategies to improve retention in RCTs, we conducted a survey of UK clinical trials units (CTUs) and made contact with RCT methodologists. Key contacts for all UK CTUs were sent a personalised email with a short questionnaire and summary protocol of the Cochrane methodology review. The questionnaire asked whether a RCT evaluating strategies to improve retention embedded in a RCT had ever been conducted by the CTU. Questions about the stage of completion and publication of such RCTs were included. The summary protocol outlined the aims, eligibility criteria, examples of types of retention strategies, and the primary outcome for the systematic review. Personal communication with RCT methodologists and presentations of preliminary results of the review at conferences were also used to identify additional eligible RCTs. We checked the results of our standard searches to see if eligible studies identified through these additional methods were also found using our standard searches. We identified 14 of the 38 RCTs included in the Cochrane methodology review by contacting trials units and methodologists. Eleven of the 14 RCTs identified by these methods were either published in grey literature, in press or unpublished. Three remaining RCTs were fully published at the time. Six of the RCTs identified were not found through any other searches. The RCTs identified represented data for 6 of 14 RCTs of incentive strategies (52% of randomised participants included in the review), and 6 of 14 RCTs of communication strategies (52% of randomised participants included in the Cochrane review). Data were unavailable for two of the RCTs identified. Methodological evaluations embedded in RCTs may be unpublished, published in the grey literature or where published, poorly indexed in bibliographic databases. To identify such studies and minimise selection bias in systematic reviews of methodological evaluations, reviewers should consider contacting CTUs and trial methodologists.

  16. Combination of psychotherapy and benzodiazepines versus either therapy alone for panic disorder: a systematic review

    PubMed Central

    Watanabe, Norio; Churchill, Rachel; Furukawa, Toshi A

    2007-01-01

    Background: The efficacy of combined psychotherapy and benzodiazepine treatment for panic disorder is still unclear despite its widespread use. The present systematic review aims to examine its efficacy compared with either monotherapy alone. Methods: All randomised trials comparing combined psychotherapy and benzodiazepine for panic disorder with either therapy alone were identified by comprehensive electronic search on the Cochrane Registers, by checking references of relevant studies and of other reviews, and by contacting experts in the field. Two reviewers independently checked eligibility of trials, assessed quality of trials and extracted data from eligible trials using a standardized data extraction form. Our primary outcome was "response" defined by global judgement. Authors of the original trials were contacted for further unpublished data. Meta-analyses were undertaken synthesizing data from all relevant trials. Results: Only two studies, which compared the combination with behaviour (exposure) therapy, met our eligibility criteria. Both studies had a 16-week intervention. Unpublished data were retrieved for one study. The relative risk for response for the combination was 1.25 (95%CI: 0.78 to 2.03) during acute phase treatment, 0.78 (0.45 to 1.35) at the end of treatment, and 0.62 (0.36 to 1.07) at 6–12 months follow-up. Some secondary outcomes hinted at superiority of the combination during acute phase treatment. One study was identified comparing the combination to benzodiazepine. The relative risk for response was 1.57 (0.83 to 2.98), 3.39 (1.03 to 11.21, statistically significant) and 2.31 (0.79 to 6.74) respectively. The superiority of the combination was observed on secondary outcomes at all the time points. No sub-group analyses were conducted due to the limited number of included trials. Conclusion: Unlike some narrative reviews in the literature, our systematic search established the paucity of high quality evidence for or against the combined psychotherapy plus benzodiazepine therapy for panic disorder. Based on limited available published and unpublished data, however, the combined therapy is probably to be recommended over benzodiazepine alone for panic disorder with agoraphobia. The combination might be superior to behaviour therapy alone during the acute phase, but afterwards this trend may be reversed. We know little from these trials about their adverse effects. PMID:17501985

  17. Map showing outcrop of the coal-bearing units and land use in the Gulf Coast region

    USGS Publications Warehouse

    Warwick, Peter D.; SanFilipo, John R.; Crowley, Sharon S.; Thomas, Roger E.; Freid, John; Tully, John K.

    1997-01-01

    This map is a preliminary compilation of the outcrop geology of the known coal-bearing units in the Gulf Coast Coal region. The map has been compiled for use in the National Coal Resource Assessment Project currently being conducted by the U.S. Geological Survey, and will be updated as the assessment progresses. The purpose of the map is to show the distribution of coal-bearing rocks in the Gulf Coastal Plain Region and to show stratigraphic correlations, transportation network, fossil-fuel burning power plants, and federally managed lands in the region. It is hoped that this map may aid coal exploration and development in the region. Geologic contacts were digitized from paper copies of the maps listed in the reference section below. The primary source of information was the 1:500,000-scale state geology map series, but larger scale maps were use to better define certain areas, notably the Jackson-Claiborne contact in western Kentucky and Tennessee for example (Olive, 1980). Contacts along state boundaries were modified to best-fit information available from the border areas. Note that coal distribution in the mapped units is not uniform. For example, the Jackson Group contains coal in Texas, but in Mississippi is not presently known to contain significant coal deposits. The unit is widespread and in part non-marine and thus of potential future interest. In contrast, the Jackson Group is not shown in Georgia where it is mostly marine and residuum (weathered material) at the surface. Tertiary age coal has also been noted in the Vicksburg Group (Oligocene) of Louisiana and Mississippi, but is not shown on this map. Contacts with mapped surficial units are not always shown. The locations of coal mine permit boundaries are based on information available at the time of publication and were obtained from the Division of Surface Mining and Reclamation, Railroad Commission of Texas, Austin, and the Injection and Mining Division, Department of Natural Resources, Baton Rouge, Louisiana. The correlation of map units and formation names generally follow Galloway and others (1991). We have placed the Paleocene-Eocene boundary in the middle of the Calvert Bluff Formation in Texas based on unpublished pollen biostratigraphy reports (N.O. Fredericksen, unpublished data, 1993; D.J. Nichols, unpublished data, 1996).

  18. Publication bias in animal research presented at the 2008 Society of Critical Care Medicine Conference.

    PubMed

    Conradi, Una; Joffe, Ari R

    2017-07-07

    To determine a direct measure of publication bias by determining subsequent full-paper publication (P) of studies reported in animal research abstracts presented at an international conference (A). We selected 100 random (using a random-number generator) A from the 2008 Society of Critical Care Medicine Conference. Using a data collection form and study manual, we recorded methodology and result variables from A. We searched PubMed and EMBASE to June 2015, and DOAJ and Google Scholar to May 2017 to screen for subsequent P. Methodology and result variables were recorded from P to determine changes in reporting from A. Predictors of P were examined using Fisher's Exact Test. 62% (95% CI 52-71%) of studies described in A were subsequently P after a median 19 [IQR 9-33.3] months from conference presentation. Reporting of studies in A was of low quality: randomized 27% (the method of randomization and allocation concealment not described), blinded 0%, sample-size calculation stated 0%, specifying the primary outcome 26%, numbers given with denominators 6%, and stating number of animals used 47%. Only being an orally presented (vs. poster presented) A (14/16 vs. 48/84, p = 0.025) predicted P. Reporting of studies in P was of poor quality: randomized 39% (the method of randomization and allocation concealment not described), likely blinded 6%, primary outcome specified 5%, sample size calculation stated 0%, numbers given with denominators 34%, and number of animals used stated 56%. Changes in reporting from A to P occurred: from non-randomized to randomized 19%, from non-blinded to blinded 6%, from negative to positive outcomes 8%, from having to not having a stated primary outcome 16%, and from non-statistically to statistically significant findings 37%. Post-hoc, using publication data, P was predicted by having positive outcomes (published 62/62, unpublished 33/38; p = 0.003), or statistically significant results (published 58/62, unpublished 20/38; p < 0.001). Only 62% (95% CI 52-71%) of animal research A are subsequently P; this was predicted by oral presentation of the A, finally having positive outcomes, and finally having statistically significant results. Publication bias is prevalent in critical care animal research.

  19. Interagency Testing Committee (ITC) Reports

    EPA Pesticide Factsheets

    The ITC's web site is a interactive vehicle that provides procedures for industry to electronically submit unpublished data and for the public (including industry) to retrieve these data and other information created or reviewed by the ITC.

  20. 75 FR 16142 - FY 2010 Special Diabetes Program for Indians Community-Directed Grant Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ... older had diagnosed diabetes (unpublished IHS Diabetes Program Statistics, 2006) compared to 7.8% for... the delinquency is attributable to the failure of the grantee organization or the individual...

  1. Interpreters Talk a Lot, Among Other Things

    ERIC Educational Resources Information Center

    Barik, Henri C.

    1972-01-01

    Exploratory study designed to provide a general overview of the simultaneous interpretation process. Based on an unpublished doctoral dissertation supported by a Public Health Service Research Grant from the National Institute of Mental Health. (VM)

  2. Micro-Editions of Unpublished Works

    ERIC Educational Resources Information Center

    Debregeas-Laurenie, Genevieve

    1977-01-01

    This article describes the micropublication program of Institut d'Ethnologie (Paris). The collection deals with ethnology, pre-history, and archeology. Material produced on microfiche includes notes from researchers' archives, rough field notes, and unique manuscripts. (Author/JAB)

  3. THE INCLINATION OF THE SOFT X-RAY TRANSIENT A0620-00 AND THE MASS OF ITS BLACK HOLE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cantrell, Andrew G.; Bailyn, Charles D.; Orosz, Jerome A.

    2010-02-20

    We analyze photometry of the soft X-ray transient A0620 - 00 spanning nearly 30 years, including previously published and previously unpublished data. Previous attempts to determine the inclination of A0620 using subsets of these data have yielded a wide range of measured values of i. Differences in the measured value of i have been due to changes in the shape of the light curve and uncertainty regarding the contamination from the disk. We give a new technique for estimating the disk fraction and find that disk light is significant in all light curves, even in the infrared. We also findmore » that all changes in the shape and normalization of the light curve originate in a variable disk component. After accounting for this disk component, we find that all the data, including light curves of significantly different shapes, point to a consistent value of i. Combining results from many separate data sets, we find i = 51.{sup 0}0 +- 0.{sup 0}9, implying M = 6.6 +- 0.25 M{sub sun}. Using our dynamical model and zero-disk stellar VIH magnitudes, we find d = 1.06 +- 0.12 kpc. Understanding the disk origin of nonellipsoidal variability may assist with making reliable determinations of i in other systems, and the fluctuations in disk light may provide a new observational tool for understanding the three-dimensional structure of the accretion disk.« less

  4. The Inclination of the Soft X-Ray Transient A0620-00 and the Mass of its Black Hole

    NASA Astrophysics Data System (ADS)

    Cantrell, Andrew G.; Bailyn, Charles D.; Orosz, Jerome A.; McClintock, Jeffrey E.; Remillard, Ronald A.; Froning, Cynthia S.; Neilsen, Joseph; Gelino, Dawn M.; Gou, Lijun

    2010-02-01

    We analyze photometry of the soft X-ray transient A0620 - 00 spanning nearly 30 years, including previously published and previously unpublished data. Previous attempts to determine the inclination of A0620 using subsets of these data have yielded a wide range of measured values of i. Differences in the measured value of i have been due to changes in the shape of the light curve and uncertainty regarding the contamination from the disk. We give a new technique for estimating the disk fraction and find that disk light is significant in all light curves, even in the infrared. We also find that all changes in the shape and normalization of the light curve originate in a variable disk component. After accounting for this disk component, we find that all the data, including light curves of significantly different shapes, point to a consistent value of i. Combining results from many separate data sets, we find i = 51fdg0 ± 0fdg9, implying M = 6.6 ± 0.25 M sun. Using our dynamical model and zero-disk stellar VIH magnitudes, we find d = 1.06 ± 0.12 kpc. Understanding the disk origin of nonellipsoidal variability may assist with making reliable determinations of i in other systems, and the fluctuations in disk light may provide a new observational tool for understanding the three-dimensional structure of the accretion disk.

  5. Searching for Rapid Orbital Decay of WASP-18b

    NASA Astrophysics Data System (ADS)

    Wilkins, Ashlee N.; Delrez, Laetitia; Barker, Adrian J.; Deming, Drake; Hamilton, Douglas; Gillon, Michael; Jehin, Emmanuel

    2017-02-01

    The WASP-18 system, with its massive and extremely close-in planet, WASP-18b (M p = 10.3M J , a = 0.02 au, P = 22.6 hr), is one of the best-known exoplanet laboratories to directly measure Q‧, the modified tidal quality factor and proxy for efficiency of tidal dissipation, of the host star. Previous analysis predicted a rapid orbital decay of the planet toward its host star that should be measurable on the timescale of a few years, if the star is as dissipative as is inferred from the circularization of close-in solar-type binary stars. We have compiled published transit and secondary eclipse timing (as observed by WASP, TRAPPIST, and Spitzer) with more recent unpublished light curves (as observed by TRAPPIST and Hubble Space Telescope) with coverage spanning nine years. We find no signature of a rapid decay. We conclude that the absence of rapid orbital decay most likely derives from Q‧ being larger than was inferred from solar-type stars and find that Q‧ ≥ 1 × 106, at 95% confidence; this supports previous work suggesting that F stars, with their convective cores and thin convective envelopes, are significantly less tidally dissipative than solar-type stars, with radiative cores and large convective envelopes.

  6. Searching for Rapid Orbital Decay of WASP-18b

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wilkins, Ashlee N.; Deming, Drake; Hamilton, Douglas

    2017-02-20

    The WASP-18 system, with its massive and extremely close-in planet, WASP-18b ( M{sub p} = 10.3 M{sub J}, a = 0.02 au, P = 22.6 hr), is one of the best-known exoplanet laboratories to directly measure Q ′, the modified tidal quality factor and proxy for efficiency of tidal dissipation, of the host star. Previous analysis predicted a rapid orbital decay of the planet toward its host star that should be measurable on the timescale of a few years, if the star is as dissipative as is inferred from the circularization of close-in solar-type binary stars. We have compiled publishedmore » transit and secondary eclipse timing (as observed by WASP, TRAPPIST, and Spitzer ) with more recent unpublished light curves (as observed by TRAPPIST and Hubble Space Telescope ) with coverage spanning nine years. We find no signature of a rapid decay. We conclude that the absence of rapid orbital decay most likely derives from Q ′ being larger than was inferred from solar-type stars and find that Q ′ ≥ 1 × 10{sup 6}, at 95% confidence; this supports previous work suggesting that F stars, with their convective cores and thin convective envelopes, are significantly less tidally dissipative than solar-type stars, with radiative cores and large convective envelopes.« less

  7. Genesis of Karl Popper's EPR-like experiment and its resonance amongst the physics community in the 1980s

    NASA Astrophysics Data System (ADS)

    Del Santo, Flavio

    2018-05-01

    I present the reconstruction of the involvement of Karl Popper in the community of physicists concerned with foundations of quantum mechanics, in the 1980s. At that time Popper gave active contribution to the research in physics, of which the most significant is a new version of the EPR thought experiment, alleged to test different interpretations of quantum mechanics. The genesis of such an experiment is reconstructed in detail, and an unpublished letter by Popper is reproduced in the present paper to show that he formulated his thought experiment already two years before its first publication in 1982. The debate stimulated by the proposed experiment as well as Popper's role in the physics community throughout 1980s is here analysed in detail by means of personal correspondence and publications.

  8. Introduction to the "Evaluating the Impact of Structural Policies on Health Inequalities and Their Social Determinants and Fostering Change" (SOPHIE) Project.

    PubMed

    Borrell, Carme; Malmusi, Davide; Muntaner, Carles

    2017-01-01

    The SOPHIE Project (acronym for Structural Policies for Health Inequalities Evaluation) has focused on evaluating the impact of structural policies on health equity, considering as such all those policies that exert a powerful influence on the structural determinants of health (e.g., patterns of social stratification, living and working conditions) and thus on health-related exposures through intermediary determinants. In these sections of the International Journal of Health Services, we present some of the main findings of the SOPHIE Project. We include both articles that summarize all the evidence already published in the project on a thematic area (such as labor market, gender, or housing) and articles that present new, unpublished evidence on a specific health inequality or policy. © The Author(s) 2016.

  9. Retraction: Nucleophagy in Human Disease: Beyond the Physiological Role. [Tohoku J. Exp. Med., 2018, 244 (1), 75-81. doi: 10.1620/tjem.244.75. Review.].

    PubMed

    2018-02-01

    Retracted Review article: Nucleophagy in Human Disease: Beyond the Physiological Role. [Tohoku J. Exp. Med., 2018, 244 (1), 75-81. doi: 10.1620/tjem.244.75.] The above Review article was published online on January 27, 2018. Soon after its publication (on February 1, 2018), Dr. Nian Fu and Prof. Linxi Chen informed the Editor-in-Chief, The Tohoku Journal of Experimental Medicine (TJEM), about serious violation of publication ethics. Indeed, Dr. Nian Fu and Prof. Linxi Chen were astonished to find their names as coauthors of this Review article, because they were not involved in the submission process of this Review article and they do not know any of other coauthors. In addition, the Review article is similar to their unpublished manuscript. After a thorough investigation in accordance with the recommendations of the Committee on Publication Ethics (COPE), the Editor-in-Chief of TJEM decided to retract this Review article. The reasons for Retraction are summarized below: forged authors and an unexpected case of plagiarism. Forged authors: Dr. Nian Fu and Prof. Linxi Chen were added as co-authors of the Review article without their knowledge. In fact, the signature provided by Prof. Linxi Chen is apparently different from the signature of a coauthor, named Linxi Chen, on the AUTHORS’ RESPONSIBILITY FORM, provided by the corresponding author of the Review article. More critically, the signature provided by Dr. Nian Fu is completely different from the signature of Nian Fu, because the Chinese characters are different between the two signatures. In addition, the replies from three authors (Ming Zhou, Hongwen Ji and Yong Xia) clearly indicate that they misunderstand the identity of Dr. Nina Fu. We also attempted to contact two authors, named Nian Fu and Linxi Chen, via e-mail. As expected, the forged authors did not respond to our inquiries, despite that their e-mail addresses appear to be active. An unexpected case of plagiarism: This Review article is similar to the unpublished manuscript prepared by Dr. Nian Fu and Prof. Linxi Chen. Moreover, two figures used in the Review article are identical to the preliminary figures of their unpublished manuscript. According to Dr. Nian Fu, a local agency for language editing had transferred their unpublished manuscript to a third party. Unfortunately, the check system of TJEM is not effective for plagiarism of unpublished materials. We believe that the corresponding author of the Review article included the names of the original two authors to avoid the criticism of plagiarism. Eventually, the corresponding author agreed to retract the Review article. We apologize for any inconvenience caused by this retraction to readers. We also hope that the publication of the plagiarized Review article will not trouble Dr. Nian Fu and Prof. Linxi Chen too much.

  10. Pilot Study EURAMET.AUV.V-P1: Bilateral comparison on magnitude of the complex charge sensitivity of accelerometers from 10 Hz to 10 kHz

    NASA Astrophysics Data System (ADS)

    Bartoli, Claire; Hermawanto, Denny

    2017-01-01

    The results of a Pilot Study EURAMET.AUV.V-P1 between LNE (France) and RCM-LIPI (Indonesia) are reported. This bilateral comparison of sinusoidal vibration was organized after the implementation of various improvements at RCM-LIPI following a previous (unpublished) comparison that had revealed discrepancies in their results at frequencies above 5 kHz. The results of this Pilot Study, using the same accelerometers as the earlier comparison, demonstrate that the discrepancies at high frequencies have been resolved. For both the back-to-back and the single-ended accelerometers tested, the sensitivities of the RCM-LIPI and the LNE over the frequency range from 10 Hz to 10 kHz now agree within their declared uncertainties. Main text To reach the main text of this paper, click on Final Report. The final report has been peer-reviewed and approved for publication by the CCAUV.

  11. Determination of formetanate hydrochloride in fruit samples using liquid chromatography-mass selective detection or -tandem mass spectrometry.

    PubMed

    Podhorniak, Lynda V; Kamel, Alaa; Rains, Diane M

    2010-05-26

    A rapid multiresidue method that captures residues of the insecticide formetanate hydrochloride (FHCl) in selected fruits is described. The method was used to provide residue data for dietary exposure determinations of FHCl. Using an acetonitrile extraction with a dispersive cleanup based on AOAC International method 2007.01, also known as QuEChERS, which was further modified and streamlined, thousands of samples were successfully analyzed for FHCl residues. FHCl levels were determined both by liquid chromatography-single-stage mass spectrometry (LC-MS) and ultraperformance liquid chromatography (UPLC)-tandem mass spectrometry (LC-MS/MS). The target limit of detection (LOD) and the limit of quantitation (LOQ) achieved for FHCl were 3.33 and 10 ng/g, respectively, with LC-MS and 0.1 and 0.3 ng/g, respectively, with LC-MS/MS. Recoveries at these previously unpublished levels ranged from 95 to 109%. A set of 20-40 samples can be prepared in one working day by two chemists.

  12. [On the astrology and computation in the 12th century: new unpublished manuscripts ].

    PubMed

    Caiazzo, Irene

    2012-01-01

    This article examines three so far unknown lemmatic commentaries on computus and on astrolabe topics, which are to be found in MS Stuttgart, Württembergische Landesbibliothek, Cod. math. 4 degrees 33 (second half of the twelfth-century). The commentaries are on the 'Compotus' by Gerlandus, on the 'De mensura astrolabii' by Hermann of Reichenau, and on the 'De utilitatibus astrolabii', which is sometimes attributed to Gerbert of Aurillac. No commentaries on the respective treatises have previously been identified as such. The commentaries of the Stuttgart manuscript are of special interest in that they allow us to understand how a twelfth-century scholar read works on computus and the astrolabe, namely works that date back to the eleventh century. Their author remains anonymous, but in all probability he wrote his commentary on the 'Compotus' by Gerlandus either in 1143 or in 1150. An appendix to the article includes transcriptions of the introductory texts on the computus and on the astrolabe as well as the beginnings of the commentaries.

  13. The Bluebirds: World War I Soldiers' Experiences of Occupational Therapy.

    PubMed

    Pettigrew, Judith; Robinson, Katie; Moloney, Stephanie

    More is known about the experience of occupational therapists than the experience of patients during the profession's early years. We examined soldiers' experiences of occupational therapy in American Base Hospital 9 in France during World War I through analysis of a 53-line poem by Corporal Frank Wren contained in the unpublished memoir of occupational therapy reconstruction aide Lena Hitchcock. Historical documentary research methods and thematic analysis were used to analyze the poem, the memoir, and the hospital's published history. The poem describes the activities engaged in during occupational therapy, equipment used, and the context of therapy. It articulates positive dimensions of the experience of engaging in activities, including emotional benefits, diversion, and orthopedic benefits. Previous historical research has identified core philosophical premises about the use of occupational therapy; in this article, the enactment of these principles is established through the analysis of a soldier's account of receiving occupational therapy. Copyright © 2017 by the American Occupational Therapy Association, Inc.

  14. Space Mechanisms Lessons Learned Study. Volume 2: Literature Review

    NASA Technical Reports Server (NTRS)

    Shapiro, Wilbur; Murray, Frank; Howarth, Roy; Fusaro, Robert

    1995-01-01

    Hundreds of satellites have been launched to date. Some have operated extremely well and others have not. In order to learn from past operating experiences, a study was conducted to determine the conditions under which space mechanisms (mechanically moving components) have previously worked or failed. The study consisted of an extensive literature review that included both government contractor reports and technical journals, communication and visits (when necessary) to the various NASA and DOD centers and their designated contractors (this included contact with project managers of current and prior NASA satellite programs as well as their industry counterparts), requests for unpublished information to NASA and industry, and a mail survey designed to acquire specific mechanism experience. The information obtained has been organized into two volumes. Volume 1 provides a summary of the lesson learned, the results of a needs analysis, responses to the mail survey, a listing of experts, a description of some available facilities, and a compilation of references. Volume 2 contains a compilation of the literature review synopsis.

  15. Two New Species of Bibloplectus Reitter (Coleoptera: Staphylinidae: Pselaphinae) from the Orlando Park Collection, Field Museum of Natural History.

    PubMed

    Owens, Brittany E; Carlton, Christopher E

    2018-04-10

    Two new species of Bibloplectus Reitter, 1881 are described from the Orlando Park Collection of Pselaphinae at the FMNH (Field Museum of Natural History, Chicago, IL, USA): Bibloplectus silvestris Owens and Carlton, new species (type locality, Urbana, IL, USA) and Bibloplectus wingi Owens and Carlton, new species (type locality, Shades State Park, IN, USA). Types of these new species were part of a series of specimens bearing unpublished Park manuscript names in both the pinned and slide collection at the FMNH. They bring the total number of species in the genus in eastern North America to twenty-three. Resolving these manuscript names adds to previous efforts to uncover elements of the hidden diversity of North American Bibloplectus from museum collections (Owens and Carlton 2016, Owens and Carlton 2017) and highlights the importance of close examination of the Orlando Park pselaphine collection as a valuable historic and taxonomic resource.

  16. Space Mechanisms Lessons Learned Study. Volume 1: Summary

    NASA Technical Reports Server (NTRS)

    Shapiro, Wilbur; Murray, Frank; Howarth, Roy; Fusaro, Robert

    1995-01-01

    Hundreds of satellites have been launched to date. Some have operated extremely well and others have not. In order to learn from past operating experiences, a study was conducted to determine the conditions under which space mechanisms (mechanically moving components) have previously worked or failed. The study consisted of: (1) an extensive literature review that included both government contractor reports and technical journals; (2) communication and visits (when necessary) to the various NASA and DOD centers and their designated contractors (this included contact with project managers of current and prior NASA satellite programs as well as their industry counterparts); (3) requests for unpublished information to NASA and industry; and (4) a mail survey designed to acquire specific mechanism experience. The information obtained has been organized into two volumes. Volume 1 provides a summary of the lessons learned, the results of a needs analysis, responses to the mail survey, a listing of experts, a description of some available facilities and a compilation of references. Volume 2 contains a compilation of the literature review synopsis.

  17. Age of the Scan Basin (Scotia Sea)

    NASA Astrophysics Data System (ADS)

    Schreider, Al. A.; Schreider, A. A.; Galindo-Zaldivar, J.; Maldonado, A.; Sazhneva, A. E.; Evsenko, E. I.

    2017-03-01

    Integrated geological and geophysical analysis of the anomalous magnetic field along with the previously unpublished profiles of Spanish expeditions onboard the R/V Hesperides and international databases of geomagnetic data processed in the context of the global tectonics concepts made it possible to identify paleomagnetic anomalies C11-C15 and compile the first map of the bottom geochronology of the Scan Basin. Unlike in earlier known publications, the paleoaxis of spreading does extend northeast, but approximately at an angle of 345°. According to calculations, spreading began 35.294‒35.706 Ma ago during chron C15r, and the spreading paleoaxis was abandoned 29.527‒29.970 Ma ago during chron C11n.2n. Thus, the destruction of the American-Antarctic bridge in the region joining the Bruce and Discovery banks with formation of oceanic crust in the Scan Basin started about 36 Ma ago. Regular spreading of the bottom has been continuing for about 6 Ma at a average rate close to 1.8 cm/year.

  18. Molecular Testing of 163 Patients with Morquio A (Mucopolysaccharidosis IVA) Identifies 39 Novel GALNS Mutations

    PubMed Central

    Morrone, A; Tylee, K.L.; Al-Sayed, M; Brusius-Facchin, A.C.; Caciotti, A.; Church, H.J.; Coll, M.J.; Davidson, K.; Fietz, M.J.; Gort, L.; Hegde, M.; Kubaski, F.; Lacerda, L.; Laranjeira, F.; Leistner-Segal, S.; Mooney, S.; Pajares, S.; Pollard, L.; Riberio, I.; Wang, R.Y.; Miller, N.

    2014-01-01

    Morquio A (Mucopolysaccharidosis IVA; MPS IVA) is an autosomal recessive lysosomal storage disorder caused by partial or total deficiency of the enzyme galactosamine-6-sulfate sulfatase (GALNS; also known as N-acetylgalactosamine-6-sulfate sulfatase) encoded by the GALNS gene. Patients who inherit two mutated GALNS gene alleles produce protein with decreased ability to degrade the glycosaminoglycans (GAGs) keratan sulfate and chondroitin 6-sulfate, thereby causing GAG accumulation within lysosomes and consequently pleiotropic disease. GALNS mutations occur throughout the gene and many mutations are identified only in single patients or families, causing difficulties both in mutation detection and interpretation. In this study, molecular analysis of 163 patients with Morquio A identified 99 unique mutations in the GALNS gene believed to negatively impact GALNS protein function, of which 39 are previously unpublished, together with 26 single-nucleotide polymorphisms. Recommendations for the molecular testing of patients, clear reporting of sequence findings, and interpretation of sequencing data are provided. PMID:24726177

  19. On the correlation of plume centerline velocity decay of turbulent acoustically excited jets

    NASA Technical Reports Server (NTRS)

    Vonglahn, Uwe H.

    1987-01-01

    Acoustic excitation was shown to alter the velocity decay and spreading characteristics of jet plumes by modifying the large-scale structures in the plume shear layer. The present work consists of reviewing and analyzing available published and unpublished experimental data in order to determine the importance and magnitude of the several variables that contribute to plume modification by acoustic excitation. Included in the study were consideration of the effects of internal and external acoustic excitation, excitation Strouhal number, acoustic excitation level, nozzle size, and flow conditions. The last include jet Mach number and jet temperature. The effects of these factors on the plume centerline velocity decay are then summarized in an overall empirical correlation.

  20. Is there still an unknown Freud? A note on the publications of Freud's texts and on unpublished documents.

    PubMed

    Falzeder, Ernst

    2007-01-01

    This article presents an overview of the existing editions of what Freud wrote (works, letters, manuscripts and drafts, diaries and calendar notes, dedications and margin notes in books, case notes, and patient calendars) and what he is recorded as having said (minutes of meetings, interviews, memoirs of and interviews with patients, family members, and followers, and other quotes). There follows a short overview of biographies of Freud and other documentation on his life. It is concluded that a wealth of material is now available to Freud scholars, although more often than not this information is used in a biased and partisan way.

  1. ["Is it an animal inside? "Melanie Klein's unpublished Don Juan Paper (1939)].

    PubMed

    Frank, Claudia

    2008-01-01

    Klein had been asked to contribute an article to the birthday number of the International Journal for Jones. The author outlines how she hurriedly wrote a text about Don Juan which, however, was rejected by the editor. Essential parts of it are presented in German translation. The manuscript is discussed in the context of Klein's published work as well as of the relevant contemporary literature. In Klein's view, Don Juan's genitality is determined by oral impulses and fears. By his manic acting out he attempts to ward off a depressive break-down. The paper ends with some reflections about why Klein--ontrary to her intention--failed to revise her manuscript for later publication.

  2. Robert Waelder and the application of psychoanalytic principles to social and political phenomena.

    PubMed

    Guttman, S A

    1986-01-01

    This presentation reveals a little-known area of Robert Waelder's work. As his literary executor, I have been privileged with access to his unpublished material, notes, and correspondence. And, of course, I am familiar with his mode of thinking. I wish to pass on some of this knowledge. What cannot be passed on, however, in some abstract intellectual way, are psychoanalytic principles themselves. Therefore, while this paper sheds light on a very particular aspect of Robert Waelder's work, it is also in some ways a cautionary tale, a plea that the reader understand what is behind the psychoanalytic point of view and its basic concepts--namely, clinical experience.

  3. Design guide for high pressure oxygen systems

    NASA Technical Reports Server (NTRS)

    Bond, A. C.; Pohl, H. O.; Chaffee, N. H.; Guy, W. W.; Allton, C. S.; Johnston, R. L.; Castner, W. L.; Stradling, J. S.

    1983-01-01

    A repository for critical and important detailed design data and information, hitherto unpublished, along with significant data on oxygen reactivity phenomena with metallic and nonmetallic materials in moderate to very high pressure environments is documented. This data and information provide a ready and easy to use reference for the guidance of designers of propulsion, power, and life support systems for use in space flight. The document is also applicable to designs for industrial and civilian uses of high pressure oxygen systems. The information presented herein are derived from data and design practices involving oxygen usage at pressures ranging from about 20 psia to 8000 psia equal with thermal conditions ranging from room temperatures up to 500 F.

  4. International migration to and from the United Kingdom, 1975-1999: consistency, change and implications for the labour market.

    PubMed

    Dobson, J; McLaughlan, G

    2001-01-01

    This article presents some findings of a recent study carried out for the Home Office by the Migration Research Unit (MRU) in the Department of Geography at UCL. The study was concerned with patterns and trends in international migration to and from the United Kingdom since 1975, with a particular focus on those in employment, and drew on many sources. The statistics analysed here derive from the International Passenger Survey, including hitherto unpublished tables provided by the Office for National Statistics on migration of the employed by citizenship. They indicate remarkable consistency in some aspects of migration flows and major change in others.

  5. Proceedings of Colloquium 110 of the International Astronomical Union on Library and Information Services in Astronomy

    NASA Astrophysics Data System (ADS)

    Wilkins, George A.; Stevens-Rayburn, Sarah

    This report provides an overview of the presentations and summaries of discussions at IAU Colloquium 110, which was held in Washington, D.C., on 26-30 July 1988 and at the Goddard Space Flight Center on 1 August 1988. The topics included: the publication and acquisition of books and journals; searching for astronomical information; the handling and use of special-format materials; conservation; archiving of unpublished documents; uses of computers in libraries; astronomical databases and various aspects of the administration of astronomy libraries and services. Particular attention was paid to new developments, but the problems of astronomers and institutions in developing countries were also considered.

  6. [Lipiodol therapeutic indications from 1901 to 1930].

    PubMed

    Bonnemain, B

    2000-01-01

    Iodine and iodide used to be very successful drugs, sometimes at massive doses. Highly iodinated oil such as lipiodol from Lafay discovered in 1901 were part of expanding the therapeutic use of iodine for various pathologies such as syphilis, cardiovascular and respiratory diseases, leprosy, goiter... The present publication reviews unpublished documents and publications from 1901 to 1930 on lipiodol to give an overview of therapeutic indications for this agent and the rationale behind it. In some areas such as asthma, iodide was still in use until the eighties. Prevention and treatment of endemic goiter is the only remaining domain for the therapeutic usage of lipiodol. It is the only reason why this product is on the WHO essential drugs list.

  7. Transplantation of the heart: An overview of 40 years' clinical and research experience at Groote Schuur Hospital and the University of Cape Town: Part II. Laboratory research experience.

    PubMed

    Hassoulas, J

    2012-03-29

    Extensive experimental research on various aspects of heart transplantation was undertaken during the first 2 decades. An overview of this work is presented, and some still unpublished work has been included. Experimental laboratory investigation was an integral activity of the cardiac transplantation programme at the University of Cape Town over these years, and has remained so ever since. These studies provided invaluable fundamental information upon which future clinical work was based. It is therefore necessary to briefly mention and discuss this information, most of which has been published in detail by the various investigators concerned.

  8. 75 FR 1389 - FY 2010 Special Diabetes Program for Indians Community-Directed Grant Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-11

    ... or older had diagnosed diabetes (unpublished IHS Diabetes Program Statistics, 2006) compared to 7.8... applies whether the delinquency is attributable to the failure of the grantee organization or the...

  9. Alteration Map Showing Major Faults and Veins and Associated Water-Quality Signatures of the Animas River Watershed Headwaters Near Silverton, Southwest Colorado

    USGS Publications Warehouse

    Bove, Dana J.; Yager, Douglas B.; Mast, M. Alisa; Dalton, J. Brad

    2007-01-01

    This map was produced to provide hard-copy and digital data for alteration assemblages in the historical mining area centered on the Tertiary San Juan and Silverton calderas. The data have direct application to geoenvironmental and mineral exploration objectives. This dataset represents alteration mapping for the upper Animas River watershed near Silverton, Colorado. The map is based on detailed 1:12,000-scale field mapping, X-ray diffraction (XRD) analysis, mineral mapping by remote sensing (AVIRIS) data, and 1:24,000-scale aerial photographic interpretation. Geologic structures were compiled and generalized from multiple published and unpublished sources (Burbank and Luedke, 1964; Steven and others, 1974; Luedke and Burbank 1975a, b; Lipman, 1976; Luedke and Burbank, 1987; Luedke, 1996) (see Index Map). Unpublished mapping of the Ironton quadrangle by D.J. Bove and J.P. Kurtz in 1997-1999 was included.

  10. Systematic documentation and analysis of human genetic variation in hemoglobinopathies using the microattribution approach.

    PubMed

    Giardine, Belinda; Borg, Joseph; Higgs, Douglas R; Peterson, Kenneth R; Philipsen, Sjaak; Maglott, Donna; Singleton, Belinda K; Anstee, David J; Basak, A Nazli; Clark, Barnaby; Costa, Flavia C; Faustino, Paula; Fedosyuk, Halyna; Felice, Alex E; Francina, Alain; Galanello, Renzo; Gallivan, Monica V E; Georgitsi, Marianthi; Gibbons, Richard J; Giordano, Piero C; Harteveld, Cornelis L; Hoyer, James D; Jarvis, Martin; Joly, Philippe; Kanavakis, Emmanuel; Kollia, Panagoula; Menzel, Stephan; Miller, Webb; Moradkhani, Kamran; Old, John; Papachatzopoulou, Adamantia; Papadakis, Manoussos N; Papadopoulos, Petros; Pavlovic, Sonja; Perseu, Lucia; Radmilovic, Milena; Riemer, Cathy; Satta, Stefania; Schrijver, Iris; Stojiljkovic, Maja; Thein, Swee Lay; Traeger-Synodinos, Jan; Tully, Ray; Wada, Takahito; Waye, John S; Wiemann, Claudia; Zukic, Branka; Chui, David H K; Wajcman, Henri; Hardison, Ross C; Patrinos, George P

    2011-03-20

    We developed a series of interrelated locus-specific databases to store all published and unpublished genetic variation related to hemoglobinopathies and thalassemia and implemented microattribution to encourage submission of unpublished observations of genetic variation to these public repositories. A total of 1,941 unique genetic variants in 37 genes, encoding globins and other erythroid proteins, are currently documented in these databases, with reciprocal attribution of microcitations to data contributors. Our project provides the first example of implementing microattribution to incentivise submission of all known genetic variation in a defined system. It has demonstrably increased the reporting of human variants, leading to a comprehensive online resource for systematically describing human genetic variation in the globin genes and other genes contributing to hemoglobinopathies and thalassemias. The principles established here will serve as a model for other systems and for the analysis of other common and/or complex human genetic diseases.

  11. Corporate influence on threshold limit values.

    PubMed

    Castleman, B I; Ziem, G E

    1988-01-01

    Investigations into the historical development of specific Threshold Limit Values (TLVs) for many substances have revealed serious shortcomings in the process followed by the American Conference of Governmental Industrial Hygienists. Unpublished corporate communications were important in developing TLVs for 104 substances; for 15 of these, the TLV documentation was based solely on such information. Efforts to obtain written copies of this unpublished material were mostly unsuccessful. Case studies on the TLV Committee's handling of lead and seven carcinogens illustrate various aspects of corporate influence and interaction with the committee. Corporate representatives listed officially as "consultants" since 1970 were given primary responsibility for developing TLVs on proprietary chemicals of the companies that employed them (Dow, DuPont). It is concluded that an ongoing international effort is needed to develop scientifically based guidelines to replace the TLVs in a climate of openness and without manipulation by vested interests.

  12. Sea-ice thickness from field measurements in the northwestern Barents Sea

    NASA Astrophysics Data System (ADS)

    King, Jennifer; Spreen, Gunnar; Gerland, Sebastian; Haas, Christian; Hendricks, Stefan; Kaleschke, Lars; Wang, Caixin

    2017-02-01

    The Barents Sea is one of the fastest changing regions of the Arctic, and has experienced the strongest decline in winter-time sea-ice area in the Arctic, at -23±4% decade-1. Sea-ice thickness in the Barents Sea is not well studied. We present two previously unpublished helicopter-borne electromagnetic (HEM) ice thickness measurements from the northwestern Barents Sea acquired in March 2003 and 2014. The HEM data are compared to ice thickness calculated from ice draft measured by ULS deployed between 1994 and 1996. These data show that ice thickness varies greatly from year to year; influenced by the thermodynamic and dynamic processes that govern local formation vs long-range advection. In a year with a large inflow of sea-ice from the Arctic Basin, the Barents Sea ice cover is dominated by thick multiyear ice; as was the case in 2003 and 1995. In a year with an ice cover that was mainly grown in situ, the ice will be thin and mechanically unstable; as was the case in 2014. The HEM data allow us to explore the spatial and temporal variability in ice thickness. In 2003 the dominant ice class was more than 2 years old; and modal sea-ice thickness varied regionally from 0.6 to 1.4 m, with the thinner ice being either first-year ice, or multiyear ice which had come into contact with warm Atlantic water. In 2014 the ice cover was predominantly locally grown ice less than 1 month old (regional modes of 0.5-0.8 m). These two situations represent two extremes of a range of possible ice thickness distributions that can present very different conditions for shipping traffic; or have a different impact on heat transport from ocean to atmosphere.

  13. "Treatises on Earthquakes" in late Renaissance (16th-17th cent), at the roots of historical seismology

    NASA Astrophysics Data System (ADS)

    Albini, P.

    2009-04-01

    It was soon after the damaging November 1570 earthquake at Ferrara, Northern Italy, that the academic Stefano Breventano from Pavia, a small town in Northern Italy as well, started to compose his "Treatise on the earthquake". Completed by September 1576, this 250-page manuscript was to remain unpublished for centuries. The critical edition recently appeared (Albini, 2007) was a due tribute to the remarkable amount of information put together by Breventano, an otherwise "obscure" literate who, before getting involved with earthquakes, had published a history of the antiquities and remarkable events at his hometown Pavia (1570). Indeed, he was not the first Renaissance author to pursue the goal of checking into the historical sources of the previous centuries in search of earthquakes and other natural phenomena. What is outstanding in his "Treatise" is that he suceeded in retrieving information on more than two hundred earthquakes, along two thousand years, between 504 B.C. and 1575 A.D., covering the whole Euro-Mediterranean region, and the West Indies in early 16th century. Breventano's essay is here presented, together with a comparison between his style and amount of information with those included in the work by the contemporary British author Stephen Batman, "The Doome warning all men to the Judgement" (1581). A later treatise is presented also, the work by Marcello Bonito (1690) "Terra Tremante [Trembling Earth]", which could easily be defined as a worldwide list of earthquakes. In structure and content, Bonito's work goes along the same lines of Breventano, and could be considered a precursor of today descriptive catalogues, because of his outstandingly modern approach that paved the way to modern historical seismology.

  14. Variants in ACTG2 underlie a substantial number of Australasian patients with primary chronic intestinal pseudo-obstruction.

    PubMed

    Ravenscroft, G; Pannell, S; O'Grady, G; Ong, R; Ee, H C; Faiz, F; Marns, L; Goel, H; Kumarasinghe, P; Sollis, E; Sivadorai, P; Wilson, M; Magoffin, A; Nightingale, S; Freckmann, M-L; Kirk, E P; Sachdev, R; Lemberg, D A; Delatycki, M B; Kamm, M A; Basnayake, C; Lamont, P J; Amor, D J; Jones, K; Schilperoort, J; Davis, M R; Laing, N G

    2018-05-21

    Primary chronic intestinal pseudo-obstruction (CIPO) is a rare, potentially life-threatening disorder characterized by severely impaired gastrointestinal motility. The objective of this study was to examine the contribution of ACTG2, LMOD1, MYH11, and MYLK mutations in an Australasian cohort of patients with a diagnosis of primary CIPO associated with visceral myopathy. Pediatric and adult patients with primary CIPO and suspected visceral myopathy were recruited from across Australia and New Zealand. Sanger sequencing of the genes encoding enteric gamma-actin (ACTG2) and smooth muscle leiomodin (LMOD1) was performed on DNA from patients, and their relatives, where available. MYH11 and MYLK were screened by next-generation sequencing. We identified heterozygous missense variants in ACTG2 in 7 of 17 families (~41%) diagnosed with CIPO and its associated conditions. We also identified a previously unpublished missense mutation (c.443C>T, p.Arg148Leu) in one family. One case presented with megacystis-microcolon-intestinal hypoperistalsis syndrome in utero with subsequent termination of pregnancy at 28 weeks' gestation. All of the substitutions identified occurred at arginine residues. No likely pathogenic variants in LMOD1, MYH11, or MYLK were identified within our cohort. ACTG2 mutations represent a significant underlying cause of primary CIPO with visceral myopathy and associated phenotypes in Australasian patients. Thus, ACTG2 sequencing should be considered in cases presenting with hypoperistalsis phenotypes with suspected visceral myopathy. It is likely that variants in other genes encoding enteric smooth muscle contractile proteins will contribute further to the genetic heterogeneity of hypoperistalsis phenotypes. © 2018 John Wiley & Sons Ltd.

  15. Chemotactic droplet swimmers in complex geometries

    NASA Astrophysics Data System (ADS)

    Jin, Chenyu; Hokmabad, Babak V.; Baldwin, Kyle A.; Maass, Corinna C.

    2018-02-01

    Chemotaxis1 and auto-chemotaxis are key mechanisms in the dynamics of micro-organisms, e.g. in the acquisition of nutrients and in the communication between individuals, influencing the collective behaviour. However, chemical signalling and the natural environment of biological swimmers are generally complex, making them hard to access analytically. We present a well-controlled, tunable artificial model to study chemotaxis and autochemotaxis in complex geometries, using microfluidic assays of self-propelling oil droplets in an aqueous surfactant solution (Herminghaus et al 2014 Soft Matter 10 7008-22 Krüger et al 2016 Phys. Rev. Lett. 117). Droplets propel via interfacial Marangoni stresses powered by micellar solubilisation. Moreover, filled micelles act as a chemical repellent by diffusive phoretic gradient forces. We have studied these chemotactic effects in a series of microfluidic geometries, as published in Jin et al (2017 Proc. Natl Acad. Sci. 114 5089-94): first, droplets are guided along the shortest path through a maze by surfactant diffusing into the maze from the exit. Second, we let auto-chemotactic droplet swimmers pass through bifurcating microfluidic channels and record anticorrelations between the branch choices of consecutive droplets. We present an analytical Langevin model matching the experimental data. In a previously unpublished experiment, pillar arrays of variable sizes and shapes provide a convex wall interacting with the swimmer and, in the case of attachment, bending its trajectory and forcing it to revert to its own trail. We observe different behaviours based on the interplay of wall curvature and negative autochemotaxis, i.e. no attachment for highly curved interfaces, stable trapping at large pillars, and a narrow transition region where negative autochemotaxis makes the swimmers detach after a single orbit.

  16. Seed wasp invasions promoted by unregulated seed trade affect vegetal and animal biodiversity.

    PubMed

    Auger-Rozenberg, Marie-Anne; Roques, Alain

    2012-09-01

    Cone and seed insects are considered the most important predators of tree seeds during the pre-dispersal phase of development. Among them, exotic seed chalcids in the genus Megastigmus invaded Europe as a result of the rapidly-increasing and mostly unregulated seed trade for afforestation and ornamental plantations. Unlike their economic impact in seed orchards, until recently, little attention was paid to the ecological impact of these insects. In the present study, selected case studies of alien Megastigmus spp. were considered to assess their specific impact on the potential of natural regeneration of native woody plants and on the native entomofauna competing for seed resource. We re-analyzed data from former studies that did not focus on these ecological interactions and, here, present previously unpublished results. Seeds of Douglas-fir, true cedars, true firs and wild roses were sampled all over Europe, and the relative importance of the native and invasive chalcid species was assessed as well as their specific impact on seed yield. In most cases, the recent arrival of alien chalcids resulted in a significant decrease in the regeneration potential of the host trees. In the absence of competitors, alien chalcids occupied the entire seed niche in Douglas-fir, but their impact tended to decrease after the arrival of invasive seed bugs. In firs, alien chalcids tended to displace the native chalcids, but not in wild roses and cedars, where their damage was increasing. Different biological traits that might explain invasive success of alien chalcids are discussed. However, no general invasive patterns seem to exist. © 2012 Wiley Publishing Asia Pty Ltd, ISZS and IOZ/CAS.

  17. The effect of cigarette smoking, alcohol consumption and fruit and vegetable consumption on IVF outcomes: a review and presentation of original data.

    PubMed

    Firns, Sarah; Cruzat, Vinicius Fernandes; Keane, Kevin Noel; Joesbury, Karen A; Lee, Andy H; Newsholme, Philip; Yovich, John L

    2015-12-16

    Lifestyle factors including cigarette smoking, alcohol consumption and nutritional habits impact on health, wellness, and the risk of chronic diseases. In the areas of in-vitro fertilization (IVF) and pregnancy, lifestyle factors influence oocyte production, fertilization rates, pregnancy and pregnancy loss, while chronic, low-grade oxidative stress may underlie poor outcomes for some IVF cases. Here, we review the current literature and present some original, previously unpublished data, obtained from couples attending the PIVET Medical Centre in Western Australia. During the study, 80 % of females and 70 % of male partners completed a 1-week diary documenting their smoking, alcohol and fruit and vegetable intake. The subsequent clinical outcomes of their IVF treatment such as quantity of oocytes collected, fertilization rates, pregnancy and pregnancy loss were submitted to multiple regression analysis, in order to investigate the relationship between patients, treatment and the recorded lifestyle factors. Of significance, it was found that male smoking caused an increased risk of pregnancy loss (p = 0.029), while female smoking caused an adverse effect on ovarian reserve. Both alcohol consumption (β = 0.074, p < 0.001) and fruit and vegetable consumption (β = 0.034, p < 0.001) had positive effects on fertilization. Based on our results and the current literature, there is an important impact of lifestyle factors on IVF clinical outcomes. Currently, there are conflicting results regarding other lifestyle factors such as nutritional habits and alcohol consumption, but it is apparent that chronic oxidative stress induced by lifestyle factors and poor nutritional habits associate with a lower rate of IVF success.

  18. The Oncolytic Virotherapy Era in Cancer Management: Prospects of Applying H-1 Parvovirus to Treat Blood and Solid Cancers

    PubMed Central

    Angelova, Assia L.; Witzens-Harig, Mathias; Galabov, Angel S.; Rommelaere, Jean

    2017-01-01

    Non-Hodgkin lymphoma (NHL) and leukemia are among the most common cancers worldwide. While the treatment of NHL/leukemia of B-cell origin has much progressed with the introduction of targeted therapies, few treatment standards have been established for T-NHL/leukemia. As presentation in both B- and T-NHL/leukemia patients is often aggressive and as prognosis for relapsed disease is especially dismal, this cancer entity poses major challenges and requires innovative therapeutic approaches. In clinical trials, oncolytic viruses (OVs) have been used against refractory multiple myeloma (MM). In preclinical settings, a number of OVs have demonstrated a remarkable ability to suppress various types of hematological cancers. Most studies dealing with this approach have used MM or B- or myeloid-cell-derived malignancies as models. Only a few describe susceptibility of T-cell lymphoma/leukemia to OV infection and killing. The rat H-1 parvovirus (H-1PV) is an OV with considerable promise as a novel therapeutic agent against both solid tumors (pancreatic cancer and glioblastoma) and hematological malignancies. The present perspective article builds on previous reports of H-1PV-driven regression of Burkitt’s lymphoma xenografts and on unpublished observations demonstrating effective killing by H-1PV of cells from CHOP-resistant diffuse large B-cell lymphoma, cutaneous T-cell lymphoma, and T-cell acute lymphoblastic leukemia. On the basis of these studies, H-1PV is proposed for use as an adjuvant to (chemo)therapeutic regimens. Furthermore, in the light of a recently completed first parvovirus clinical trial in glioblastoma patients, the advantages of H-1PV for systemic application are discussed. PMID:28553616

  19. Preliminary seismic characterization of parts of the island of Gotland in preparation for a potential CO2 storage test site

    NASA Astrophysics Data System (ADS)

    Lydersen, Ida; Sopher, Daniel; Juhlin, Christopher

    2015-04-01

    Geological storage of CO2 is one of the available options to reduce CO2-emissions from large point sources. Previous work in the Baltic Sea Basin has inferred a large storage potential in several stratigraphic units. The most promising of these is the Faludden sandstone, exhibiting favorable reservoir properties and forming a regional stratigraphic trap. A potential location for a pilot CO2 injection site, to explore the suitability of the Faludden reservoir is onshore Gotland, Sweden. In this study onshore and offshore data have been digitized and interpreted, along with well data, to provide a detailed characterization of the Faludden reservoir below parts of Gotland. Maps and regional seismic profiles describing the extent and top structure of the Faludden sandstone are presented. The study area covers large parts of the island of Gotland, and extends about 50-70km offshore. The seismic data presented is part of a larger dataset acquired by Oljeprospektering AB (OPAB) between 1970 and 1990. The dataset is to this date largely unpublished, therefore re-processing and interpretation of these data provide improved insight into the subsurface of the study area. Two longer seismic profiles crossing Gotland ENE-WSW have been interpreted to give a large scale, regional control of the Faludden sandstone. A relatively tight grid of land seismic following the extent of the Faludden sandstone along the eastern coast to the southernmost point has been interpreted to better understand the actual distribution and geometry of the Faludden sandstone beneath Gotland. The maps from this study help to identify the most suitable area for a potential test injection site for CO2-storage, and to further the geological understanding of the area in general.

  20. Hydrologic Investigations Concerning Lead Mining Issues in Southeastern Missouri

    USGS Publications Warehouse

    Kleeschulte, Michael J.

    2008-01-01

    Good stewardship of our Nation's natural resources demands that the extraction of exploitable, minable ore deposits be conducted in harmony with the protection of the environment, a dilemma faced by many land and water management agencies in the Nation's mining areas. As ore is mined, milled, and sent to the smelter, it leaves footprints where it has been in the form of residual trace metals. Often these footprints become remnants that can be detrimental to other natural resources. This emphasizes the importance of understanding the earth's complex physical and biological processes and their interactions at increasingly smaller scales because subtle changes in one component can substantially affect others. Understanding these changes and resulting effects requires an integrated, multidisciplinary scientific approach. As ore reserves are depleted in one area, additional exploitable deposits are required to replace them, and at times these new deposits are discovered in previously unmined areas. Informed decisions concerning resource management in these new, proposed mining areas require an understanding of the potential consequences of the planned mining actions. This understanding is usually based on knowledge that has been accumulated from studying previously mined areas with similar geohydrologic and biologic conditions. If the two areas experience similar mining practices, the information should be transferable. Lead and zinc mining along the Viburnum Trend Subdistrict of southeastern Missouri has occurred for more than 40 years. Additional potentially exploitable deposits have been discovered 30 miles to the south, within the Mark Twain National Forest. It is anticipated that the observation of current (2008) geohydrologic conditions in the Viburnum Trend can provide insight to land managers that will help reasonably anticipate the potential mining effects should additional mining occur in the exploration area. The purpose of this report is to present a compilation of previously unpublished information that was collected as part of a larger multidisciplinary study of lead mining issues in southeastern Missouri. The report resulted from the application of a multidisciplinary approach to investigate current hydrologic and biologic conditions in streams of the Viburnum Trend and the exploration area in the Mark Twain National Forest.

  1. Mycetoma (Madura Foot) in Israel: Recent Cases and a Systematic Review of the Literature

    PubMed Central

    Bitan, Ohad; Wiener-Well, Yonit; Segal, Rina; Schwartz, Eli

    2017-01-01

    Mycetoma is a chronic soft tissue infection caused by fungal or bacterial pathogens, and is endemic in tropical and subtropical regions. Cases in developed countries outside the mycetoma belt are rare and usually imported by immigrants. Sporadic cases have been reported in Israel. Unpublished cases in the participating medical centers are reported. In addition, a systematic review of the literature was performed. All published mycetoma cases diagnosed in Israel were included with relevant variables collected. Twenty-one cases of mycetoma were diagnosed in Israel between 1942 and 2015, including four unpublished cases and 17 published cases. The mean age at diagnosis was 42 years (range 23–73), and 16 of the patients were male. The foot was the primary involved organ. Fifteen patients were immigrants from Yemen, Ethiopia, and Sudan. Five cases were autochthonous. One case was travel related. Among patients who developed symptoms after immigration, the mean time from exposure to symptom onset was 5.6 years (range 1–10 years). The mean time from symptom onset to diagnosis was 6.6 years (range 0.2–35 years). The autochthonous cases demonstrate that Israel is endemic of mycetoma. The immigrant population represents two distinct waves of immigration to Israel in the past century. Two unpublished cases of Ethiopian immigrants are the first reported cases of mycetoma acquired in Ethiopia. The diagnostic and therapeutic challenges along with the epidemiological data emphasize the need of raising the awareness of physicians to this devastating condition even in developed countries. PMID:28719270

  2. Giuliano Vanghetti and the innovation of “cineplastic operations”

    PubMed Central

    Mazzoni, Alberto; Micera, Silvestro; Corbo, Massimo

    2017-01-01

    Objective: Developing functional artificial limbs for amputees has been a centuries-old challenge in medicine. We review the mechanical and neurologic principles of “cineplastic operations” and “plastic motors” used to restore movements in prostheses, with special attention to the work of Giuliano Vanghetti. Methods: We evaluated original publications describing cineplastic operations, biographic information, writings, drawings, and unpublished letters from the Vanghetti library, preserved in Empoli, Italy, and performed a bibliographic search and comparison for similar procedures in the literature. Results: Vanghetti's method for cineplastic operations differs from similar previous methods, being the first aimed at exploiting natural movements of the remnant muscles to activate the mechanical prosthesis, and the first to do so by directly connecting the prosthesis to the residual muscles and tendons. This represented a frame-changing innovation for that time and paved the way for current neuroprosthetic approaches. The first description of the method was published in 1898 and human studies started in 1900. The results of these studies were presented in 1905 and published in 1906 in Plastic and Kinematic Prosthesis. A German surgeon, Ferdinand Sauerbruch, often acknowledged as the inventor of the method, published his first results in 1915. Conclusions: Vanghetti was the first to accurately perform and describe cineplastic operations for patients following an upper arm amputation. He considered the neurologic implications of the problem and, perhaps in an effort to provide more appropriate proprioceptive feedback, he intuitively applied the prostheses so that they were functionally activated by the muscles of the proximal stump. PMID:28993523

  3. Snoring-Induced Vibratory Angioedema.

    PubMed

    Kalathoor, Ipe

    2015-10-01

    Vibratory angioedema (VA) is a rare physical urticaria, with symptoms of itching and swelling of the skin or mucosa when it is exposed to vibration. Avoidance of vibration is the best way to manage this condition. This case report will assist physicians to diagnose this rare condition. Here, a previously unpublished potential successful treatment modality is being presented, with good symptom control, along with some photographs taken during an acute attack. A literature review points towards potential undiagnosed cases. A 70-year-old woman had multiple emergency department visits for tongue and throat swelling over 3 years. The episodes always happened at night. Detailed history elicited some episodes of itching and swelling of hands when driving as well as significant snoring while sleeping. Physical examination was unremarkable except for morbid obesity. Complement factor 4 and C1esterase inhibitor level were within normal limits. A tentative diagnosis of angioedema induced by oropharyngeal vibration from snoring was made. A sleep study confirmed sleep apnea with severe snoring. After CPAP (continuous positive airway pressure) treatment, she had successful symptom control. Snoring-induced VA is very likely an under-diagnosed condition in the community. The typical history is the key to the diagnosis. This condition could be confirmed by vibration test or by the resolution of symptoms with elimination of vibration. Effective symptom control is possible by avoidance of oropharyngeal vibration from snoring with the administration of CPAP therapy, making it a potential novel indication for this condition.

  4. The Maritime Continent and Coral Triangle: How to make informed measurements in the year of the MC to improve coral protection?

    NASA Astrophysics Data System (ADS)

    Goodkin, N.; Tanzil, J.; Murty, S. A.; Ramos, R.; Pullen, J. D.

    2016-12-01

    The Maritime Continent (MC) is a region of highly complex oceanography, encompassing a majority of the Coral Triangle, the most important region for coral biodiversity and cover. Intricate coastal processes including water body mixing, resulting from reversing monsoon winds and internal waves, expose corals to a wide variety of physical conditions. However, the pressures of climate change, overfishing, ocean acidification, and coastal development, to name a few, are significant in this region and threaten to challenge reefs over the next several decades. In order to predict and study how to facilitate reef recovery in the MC region, it is crucial to understand the environmental parameters for coral success. In this presentation, we will provide an overview of oceanographic processes on the maritime continent that drive seasonal variability in the waters of the MC, including changes to sea surface temperature, salinity, pH, turbidity, productivity and nutrients. Each of these parameters is known to have impacts on calcification rates and thus coral reef formation. Environmental conditions and currents can combine to facilitate larval dispersion or to exacerbate coral disease and predation, including crown of thorns outbreaks. Internal waves may protect against coral bleaching by lowering temperatures with the delivery of deeper water. Drawing on previously published and unpublished results, we will evaluate the parameters that may be impacting reef growth rates, biodiversity and resilience in a changing world in an effort to help plan for key measurements in the year of the MC.

  5. Global magnitude of visual impairment caused by uncorrected refractive errors in 2004

    PubMed Central

    Pascolini, Donatella; Mariotti, Silvio P; Pokharel, Gopal P

    2008-01-01

    Abstract Estimates of the prevalence of visual impairment caused by uncorrected refractive errors in 2004 have been determined at regional and global levels for people aged 5 years and over from recent published and unpublished surveys. The estimates were based on the prevalence of visual acuity of less than 6/18 in the better eye with the currently available refractive correction that could be improved to equal to or better than 6/18 by refraction or pinhole. A total of 153 million people (range of uncertainty: 123 million to 184 million) are estimated to be visually impaired from uncorrected refractive errors, of whom eight million are blind. This cause of visual impairment has been overlooked in previous estimates that were based on best-corrected vision. Combined with the 161 million people visually impaired estimated in 2002 according to best-corrected vision, 314 million people are visually impaired from all causes: uncorrected refractive errors become the main cause of low vision and the second cause of blindness. Uncorrected refractive errors can hamper performance at school, reduce employability and productivity, and generally impair quality of life. Yet the correction of refractive errors with appropriate spectacles is among the most cost-effective interventions in eye health care. The results presented in this paper help to unearth a formerly hidden problem of public health dimensions and promote policy development and implementation, programmatic decision-making and corrective interventions, as well as stimulate research. PMID:18235892

  6. A high-resolution mid-Pleistocene temperature record from Arctic Lake El'gygytgyn: a 50 kyr super interglacial from MIS 33 to MIS 31?

    NASA Astrophysics Data System (ADS)

    de Wet, Gregory A.; Castañeda, Isla S.; DeConto, Robert M.; Brigham-Grette, Julie

    2016-02-01

    Previous periods of extreme warmth in Earth's history are of great interest in light of current and predicted anthropogenic warming. Numerous so called "super interglacial" intervals, with summer temperatures significantly warmer than today, have been identified in the 3.6 million year (Ma) sediment record from Lake El'gygytgyn, northeast Russia. To date, however, a high-resolution paleotemperature reconstruction from any of these super interglacials is lacking. Here we present a paleotemperature reconstruction based on branched glycerol dialkyl glycerol tetraethers (brGDGTs) from Marine Isotope Stages (MIS) 35 to MIS 29, including super interglacial MIS 31. To investigate this period in detail, samples were analyzed with an unprecedented average sample resolution of 500 yrs from MIS 33 to MIS 30. Our results suggest the entire period currently defined as MIS 33-31 (∼1114-1062 kyr BP) was characterized by generally warm and highly variable conditions at the lake, at times out of phase with Northern Hemisphere summer insolation, and that cold "glacial" conditions during MIS 32 lasted only a few thousand years. Close similarities are seen with coeval records from high southern latitudes, supporting the suggestion that the interval from MIS 33 to MIS 31 was an exceptionally long interglacial (Teitler et al., 2015). Based on brGDGT temperatures from Lake El'gygytgyn (this study and unpublished results), warming in the western Arctic during MIS 31 was matched only by MIS 11 during the Pleistocene.

  7. Sea surface microlayers: A unified physicochemical and biological perspective of the air-ocean interface

    NASA Astrophysics Data System (ADS)

    Cunliffe, Michael; Engel, Anja; Frka, Sanja; Gašparović, Blaženka; Guitart, Carlos; Murrell, J. Colin; Salter, Matthew; Stolle, Christian; Upstill-Goddard, Robert; Wurl, Oliver

    2013-02-01

    The sea surface microlayer (SML) covers more than 70% of the Earth's surface and is the boundary layer interface between the ocean and the atmosphere. This important biogeochemical and ecological system is critical to a diverse range of Earth system processes, including the synthesis, transformation and cycling of organic material, and the air-sea exchange of gases, particles and aerosols. In this review we discuss the SML paradigm, taking into account physicochemical and biological characteristics that define SML structure and function. These include enrichments in biogenic molecules such as carbohydrates, lipids and proteinaceous material that contribute to organic carbon cycling, distinct microbial assemblages that participate in air-sea gas exchange, the generation of climate-active aerosols and the accumulation of anthropogenic pollutants with potentially serious implications for the health of the ocean. Characteristically large physical, chemical and biological gradients thus separate the SML from the underlying water and the available evidence implies that the SML retains its integrity over wide ranging environmental conditions. In support of this we present previously unpublished time series data on bacterioneuston composition and SML surfactant activity immediately following physical SML disruption; these imply timescales of the order of minutes for the reestablishment of the SML following disruption. A progressive approach to understanding the SML and hence its role in global biogeochemistry can only be achieved by considering as an integrated whole, all the key components of this complex environment.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Karpetis, Adionos N.; Chen, J. Y.; Barlow, Robert S.

    Previously unpublished results from multiscalar point measurements in the series of piloted CH{sub 4}/air jet flames [R.S. Barlow, J.H. Frank, Proc. Combust. Inst. 27 (1998) 1087-1095] are presented and analyzed. The emphasis is on features of the data that reveal the relative importance of molecular diffusion and turbulent transport in these flames. The complete series A-F is considered. This includes laminar, transitional, and turbulent flames spanning a range in Reynolds number from 1100 to 44,800. Results on conditional means of species mass fractions, the differential diffusion parameter, and the state of the water-gas shift reaction all show that there ismore » an evolution in these flames from a scalar structure dominated by molecular diffusion to one dominated by turbulent transport. Long records of 6000 single-point samples at each of several selected locations in flame D are used to quantify the cross-stream (radial) dependence of conditional statistics of measured scalars. The cross-stream dependence of the conditional scalar dissipation is determined from 6000-shot, line-imaging measurements at selected locations. The cross-stream dependence of reactive scalars, which is most significant in the near field of the jet flame, is attributed to radial differences in both convective and local time scales of the flow. Results illustrate some potential limitations of common modeling assumptions when applied to laboratory-scale flames and, thus, provide a more complete context for interpretation of comparisons between experiments and model calculations.« less

  9. Identification and Categorization of Accidents and Injuries in Cabs of Locomotives

    DOT National Transportation Integrated Search

    1972-09-01

    A review and categorization is made of available published locomotive cab accident reports and statistics, as well as of unpublished accident reports from a number of individual railroads. Major hazards related to locomotive control compartment accid...

  10. Initial test results with single cylinder rhombic drive Stirling engine

    NASA Technical Reports Server (NTRS)

    Cairelli, J. E.

    1978-01-01

    A brief description is given of the GPU 3-2 hardware, the test methods used, and the result of these tests. Comparison is made to unpublished data from similar hydrogen tests performed by the U.S. Army.

  11. Communication & Aging.

    ERIC Educational Resources Information Center

    Arnold, William E.

    This extensive bibliography contains more than 1,800 entries about communication and aging. The citations include journal articles, unpublished papers, speeches, dissertations, research studies, and books that relate aging and the aged to a variety of topics, including the following: physiological deterioration, socialization, political…

  12. Some facts and opinions about specifications for asphalt cement.

    DOT National Transportation Integrated Search

    1980-01-01

    This is a synthesis of information drawn from published reports as well as unpublished memoranda and committee reports available to the author because of his earlier involvement in the development of specifications for asphalt in the American Associa...

  13. MoonDB — A Data System for Analytical Data of Lunar Samples

    NASA Astrophysics Data System (ADS)

    Lehnert, K.; Ji, P.; Cai, M.; Evans, C.; Zeigler, R.

    2018-04-01

    MoonDB is a data system that makes analytical data from the Apollo lunar sample collection and lunar meteorites accessible by synthesizing published and unpublished datasets in a relational database with an online search interface.

  14. Systematic review with meta-analysis: the effects of rifaximin in hepatic encephalopathy.

    PubMed

    Kimer, N; Krag, A; Møller, S; Bendtsen, F; Gluud, L L

    2014-07-01

    Rifaximin is recommended for prevention of hepatic encephalopathy (HE). The effects of rifaximin on overt and minimal HE are debated. To perform a systematic review and meta-analysis of randomised controlled trials (RCTs) on rifaximin for HE. We performed electronic and manual searches, gathered information from the U.S. Food and Drug Administration Home Page, and obtained unpublished information on trial design and outcome measures from authors and pharmaceutical companies. Meta-analyses were performed and results presented as risk ratios (RR) with 95% confidence intervals (CI) and the number needed to treat. Subgroup, sensitivity, regression and sequential analyses were performed to evaluate the risk of bias and sources of heterogeneity. We included 19 RCTs with 1370 patients. Outcomes were recalculated based on unpublished information of 11 trials. Overall, rifaximin had a beneficial effect on secondary prevention of HE (RR: 1.32; 95% CI 1.06-1.65), but not in a sensitivity analysis on rifaximin after TIPSS (RR: 1.27; 95% CI 1.00-1.53). Rifaximin increased the proportion of patients who recovered from HE (RR: 0.59; 95% CI: 0.46-0.76) and reduced mortality (RR: 0.68, 95% CI 0.48-0.97). The results were robust to adjustments for bias control. No small study effects were identified. The sequential analyses only confirmed the results of the analysis on HE recovery. Rifaximin has a beneficial effect on hepatic encephalopathy and may reduce mortality. The combined evidence suggests that rifaximin may be considered in the evidence-based management of hepatic encephalopathy. © 2014 John Wiley & Sons Ltd.

  15. The mammalian faunas endemic to the Cerrado and the Caatinga.

    PubMed

    Gutiérrez, Eliécer E; Marinho-Filho, Jader

    2017-01-01

    We undertook a comprehensive, critical review of literature concerning the distribution, conservation status, and taxonomy of species of mammals endemic to the Cerrado and the Caatinga, the two largest biomes of the South American Dry-Diagonal. We present species accounts and lists of species, which we built with criteria that, in our opinion, yielded results with increased scientific rigor relative to previously published lists - e.g., excluding nominal taxa whose statuses as species have been claimed only on the basis of unpublished data, incomplete taxonomic work, or weak evidence. For various taxa, we provided arguments regarding species distributions, conservation and taxonomic statuses previously lacking in the literature. Two major findings are worth highlighting. First, we unveil the existence of a group of species endemic to both the Cerrado and the Caatinga (i.e., present in both biomes and absent in all other biomes). From the biogeographic point of view, this group, herein referred to as Caatinga-Cerrado endemics, deserves attention as a unit - just as in case of the Caatinga-only and the Cerrado-only endemics. We present preliminary hypotheses on the origin of these three endemic faunas (Cerrado-only, Caatinga-only, and Caatinga-Cerrado endemics). Secondly, we discovered that a substantial portion of the endemic mammalian faunas of the Caatinga and the Cerrado faces risks of extinction that are unrecognized in the highly influential Red List of Threatened Species published by the International Union for Conservation of Nature (IUCN). "Data deficient" is a category that misrepresents the real risks of extinction of these species considering that (a) some of these species are known only from a handful of specimens collected in a single or a few localities long ago; (b) the Cerrado and the Caatinga have been sufficiently sampled to guarantee collection of additional specimens of these species if they were abundant; (c) natural habitats of the Cerrado and the Caatinga have been substantially altered or lost in recent decades. Failures either in the design of the IUCN criteria or in their application to assign categories of extinction risks represent an additional important threat to these endemic faunas because their real risks of extinctions become hidden. It is imperative to correct this situation, particularly considering that these species are associated to habitats that are experiencing fast transformation into areas for agriculture, at an unbearable cost for biodiversity.

  16. The mammalian faunas endemic to the Cerrado and the Caatinga

    PubMed Central

    Gutiérrez, Eliécer E.; Marinho-Filho, Jader

    2017-01-01

    Abstract We undertook a comprehensive, critical review of literature concerning the distribution, conservation status, and taxonomy of species of mammals endemic to the Cerrado and the Caatinga, the two largest biomes of the South American Dry-Diagonal. We present species accounts and lists of species, which we built with criteria that, in our opinion, yielded results with increased scientific rigor relative to previously published lists – e.g., excluding nominal taxa whose statuses as species have been claimed only on the basis of unpublished data, incomplete taxonomic work, or weak evidence. For various taxa, we provided arguments regarding species distributions, conservation and taxonomic statuses previously lacking in the literature. Two major findings are worth highlighting. First, we unveil the existence of a group of species endemic to both the Cerrado and the Caatinga (i.e., present in both biomes and absent in all other biomes). From the biogeographic point of view, this group, herein referred to as Caatinga-Cerrado endemics, deserves attention as a unit – just as in case of the Caatinga-only and the Cerrado-only endemics. We present preliminary hypotheses on the origin of these three endemic faunas (Cerrado-only, Caatinga-only, and Caatinga-Cerrado endemics). Secondly, we discovered that a substantial portion of the endemic mammalian faunas of the Caatinga and the Cerrado faces risks of extinction that are unrecognized in the highly influential Red List of Threatened Species published by the International Union for Conservation of Nature (IUCN). “Data deficient” is a category that misrepresents the real risks of extinction of these species considering that (a) some of these species are known only from a handful of specimens collected in a single or a few localities long ago; (b) the Cerrado and the Caatinga have been sufficiently sampled to guarantee collection of additional specimens of these species if they were abundant; (c) natural habitats of the Cerrado and the Caatinga have been substantially altered or lost in recent decades. Failures either in the design of the IUCN criteria or in their application to assign categories of extinction risks represent an additional important threat to these endemic faunas because their real risks of extinctions become hidden. It is imperative to correct this situation, particularly considering that these species are associated to habitats that are experiencing fast transformation into areas for agriculture, at an unbearable cost for biodiversity. PMID:28144187

  17. Personal sound zone reproduction with room reflections

    NASA Astrophysics Data System (ADS)

    Olik, Marek

    Loudspeaker-based sound systems, capable of a convincing reproduction of different audio streams to listeners in the same acoustic enclosure, are a convenient alternative to headphones. Such systems aim to generate "sound zones" in which target sound programmes are to be reproduced with minimum interference from any alternative programmes. This can be achieved with appropriate filtering of the source (loudspeaker) signals, so that the target sound's energy is directed to the chosen zone while being attenuated elsewhere. The existing methods are unable to produce the required sound energy ratio (acoustic contrast) between the zones with a small number of sources when strong room reflections are present. Optimization of parameters is therefore required for systems with practical limitations to improve their performance in reflective acoustic environments. One important parameter is positioning of sources with respect to the zones and room boundaries. The first contribution of this thesis is a comparison of the key sound zoning methods implemented on compact and distributed geometrical source arrangements. The study presents previously unpublished detailed evaluation and ranking of such arrangements for systems with a limited number of sources in a reflective acoustic environment similar to a domestic room. Motivated by the requirement to investigate the relationship between source positioning and performance in detail, the central contribution of this thesis is a study on optimizing source arrangements when strong individual room reflections occur. Small sound zone systems are studied analytically and numerically to reveal relationships between the geometry of source arrays and performance in terms of acoustic contrast and array effort (related to system efficiency). Three novel source position optimization techniques are proposed to increase the contrast, and geometrical means of reducing the effort are determined. Contrary to previously published case studies, this work presents a systematic examination of the key problem of first order reflections and proposes general optimization techniques, thus forming an important contribution. The remaining contribution considers evaluation and comparison of the proposed techniques with two alternative approaches to sound zone generation under reflective conditions: acoustic contrast control (ACC) combined with anechoic source optimization and sound power minimization (SPM). The study provides a ranking of the examined approaches which could serve as a guideline for method selection for rooms with strong individual reflections.

  18. C-5M Fuel Efficiency Through MFOQA Data Analysis

    DTIC Science & Technology

    2015-03-26

    deterioration of commercial high-bypass ratio turbofan engines. ( No. 801118).SAE Technical Paper. Mirtich, J. M. (2011). Cost index flying. (Unpublished...D. L. (2010). Constrained kalman filtering via density function truncation for turbofan engine health estimation. International Journal of Systems

  19. 48 CFR 41.204 - GSA areawide contracts.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... authorization form for ordering service, connection, disconnection, or change in service. Upon execution of an... services, without further negotiation, at the current, applicable published or unpublished rates, unless...) 26, Award/Contract, along with any modifications such as connection charges, special facilities, or...

  20. Unitarity in the Brout-Englert-Higgs Mechanism for Gravity

    NASA Astrophysics Data System (ADS)

    't Hooft, G.

    2010-12-01

    DISCUSSION by CHAIRMAN: G. 't HOOFT, Scientific Secretaries: O. Lychkovskiy, P. Putrov Note from Publisher: The Contents of the Lecture: "Unitarity in the Brout-Englert-Higgs Mechanism for Gravity" can be found at arXiv:0708.3184 (hep-th). Unpublished.

  1. BIBLIOGRAPHY ON CURRICULUM DEVELOPMENT.

    ERIC Educational Resources Information Center

    Harvard Univ., Cambridge, MA. Graduate School of Education.

    THIS BIBLIOGRAPHY LISTS MATERIALS ON VARIOUS ASPECTS OF CURRICULUM DEVELOPMENT. FORTY UNANNOTATED REFERENCES ARE PROVIDED FOR DOCUMENTS DATING FROM 1960 TO 1966. BOOKS, JOURNALS, REPORT MATERIALS, AND SOME UNPUBLISHED MANUSCRIPTS ARE LISTED IN SUCH AREAS AS COGNITIVE STUDIES, VOCATIONAL REHABILITATION, INSTRUCTIONAL MATERIALS, SCIENCE STUDIES, AND…

  2. FPGAs and HPC

    DTIC Science & Technology

    2007-01-01

    Ridge Technology, internal unpublished document. 10. Byoungro, S.; Diniz , P. C.; Hall, M. W. Using Estimates From Behavioral Synthesis Tools in...WIERSCHKE OLAC PL/RKFE 10 E SATURN BLVD EDWARDS AFB CA 93524-7680 1 NVL RSRCH LAB D PAPCONSTANTOPOULOS WASHINGTON DC 20375-5000 1

  3. Analysis of Neural Systems Involved in Modulation of Memory Storage

    DTIC Science & Technology

    1993-02-01

    doses of the muscarinic cholinergic agonist oxotremorine (Castellano and McGaugh, 1991). In experiments (unpublished) using intra- amygdala injections...and McGaugh, J.L. Oxotremorine attenuates retrograde amnesia induced by posttraining administration of the, GABAergic agonists muscimol and baclofen

  4. In vivo reflectance confocal microscopy imaging of melanocytic skin lesions: consensus terminology glossary and illustrative images.

    PubMed

    Scope, Alon; Benvenuto-Andrade, Cristiane; Agero, Anna-Liza C; Malvehy, Josep; Puig, Susana; Rajadhyaksha, Milind; Busam, Klaus J; Marra, Diego E; Torres, Abel; Propperova, Iva; Langley, Richard G; Marghoob, Ashfaq A; Pellacani, Giovanni; Seidenari, Stefania; Halpern, Allan C; Gonzalez, Salvador

    2007-10-01

    Reflectance confocal microscopy (RCM) has been used for over 10 years for in vivo skin imaging. However, to date no standard RCM terminology has been published. To establish a glossary of terms for RCM evaluation of melanocytic lesions. Prominent RCM researchers were presented with RCM images of melanocytic lesions. Reviewers evaluated RCM images for image quality, lesion architecture, and cellular details. Reviewers could utilize published descriptors or contribute unpublished terminology to describe lesion attributes. An online meeting was conducted to reach consensus that integrates and defines existing and new RCM descriptive terms. We present a glossary with descriptors of image quality, normal skin morphology, lesion architecture, and cellular details for RCM evaluation of melanocytic lesions. Usefulness of the glossary in RCM diagnosis of melanocytic lesions needs to be assessed. Standardization of terminology is important toward implementation of RCM in the clinical setting.

  5. Maximum Marginal Likelihood Estimation of a Monotonic Polynomial Generalized Partial Credit Model with Applications to Multiple Group Analysis.

    PubMed

    Falk, Carl F; Cai, Li

    2016-06-01

    We present a semi-parametric approach to estimating item response functions (IRF) useful when the true IRF does not strictly follow commonly used functions. Our approach replaces the linear predictor of the generalized partial credit model with a monotonic polynomial. The model includes the regular generalized partial credit model at the lowest order polynomial. Our approach extends Liang's (A semi-parametric approach to estimate IRFs, Unpublished doctoral dissertation, 2007) method for dichotomous item responses to the case of polytomous data. Furthermore, item parameter estimation is implemented with maximum marginal likelihood using the Bock-Aitkin EM algorithm, thereby facilitating multiple group analyses useful in operational settings. Our approach is demonstrated on both educational and psychological data. We present simulation results comparing our approach to more standard IRF estimation approaches and other non-parametric and semi-parametric alternatives.

  6. Quantifying uncertainty in carbon and nutrient pools of coarse woody debris

    NASA Astrophysics Data System (ADS)

    See, C. R.; Campbell, J. L.; Fraver, S.; Domke, G. M.; Harmon, M. E.; Knoepp, J. D.; Woodall, C. W.

    2016-12-01

    Woody detritus constitutes a major pool of both carbon and nutrients in forested ecosystems. Estimating coarse wood stocks relies on many assumptions, even when full surveys are conducted. Researchers rarely report error in coarse wood pool estimates, despite the importance to ecosystem budgets and modelling efforts. To date, no study has attempted a comprehensive assessment of error rates and uncertainty inherent in the estimation of this pool. Here, we use Monte Carlo analysis to propagate the error associated with the major sources of uncertainty present in the calculation of coarse wood carbon and nutrient (i.e., N, P, K, Ca, Mg, Na) pools. We also evaluate individual sources of error to identify the importance of each source of uncertainty in our estimates. We quantify sampling error by comparing the three most common field methods used to survey coarse wood (two transect methods and a whole-plot survey). We quantify the measurement error associated with length and diameter measurement, and technician error in species identification and decay class using plots surveyed by multiple technicians. We use previously published values of model error for the four most common methods of volume estimation: Smalian's, conical frustum, conic paraboloid, and average-of-ends. We also use previously published values for error in the collapse ratio (cross-sectional height/width) of decayed logs that serves as a surrogate for the volume remaining. We consider sampling error in chemical concentration and density for all decay classes, using distributions from both published and unpublished studies. Analytical uncertainty is calculated using standard reference plant material from the National Institute of Standards. Our results suggest that technician error in decay classification can have a large effect on uncertainty, since many of the error distributions included in the calculation (e.g. density, chemical concentration, volume-model selection, collapse ratio) are decay-class specific.

  7. Improving publication rates in a collaborative clinical trials research network.

    PubMed

    Archer, Stephanie Wilson; Carlo, Waldemar A; Truog, William E; Stevenson, David K; Van Meurs, Krisa P; Sánchez, Pablo J; Das, Abhik; Devaskar, Uday; Nelin, Leif D; Petrie Huitema, Carolyn M; Crawford, Margaret M; Higgins, Rosemary D

    2016-10-01

    Unpublished results can bias biomedical literature, favoring positive over negative findings, primary over secondary analyses, and can lead to duplicate studies that unnecessarily endanger subjects and waste resources. The Neonatal Research Network's (NRN) publication policies for approving, reviewing, and tracking abstracts and papers work to combat these problems. In 2003, the NRN restricted investigators with unfinished manuscripts from proposing new ones and in 2010, urged authors to complete long-outstanding manuscripts. Data from 1991 to 2015 were analyzed to determine effectiveness of these policy changes. The NRN has achieved an overall publication rate of 78% for abstracts. For 1990-2002, of 137 abstracts presented, 43 (31%) were published within 2 years; for 2003-2009, after the manuscript completion policy was instituted, of 140 abstracts presented, 68 (49%) were published within 2 years. Following the effort in 2010, the rate increased to 64%. The NRN surpassed reported rates by developing a comprehensive process, holding investigators accountable and tracking abstracts from presentation to publication. Copyright © 2016. Published by Elsevier Inc.

  8. Improving publication rates in a collaborative clinical trials research network

    PubMed Central

    Archer, Stephanie Wilson; Carlo, Waldemar A.; Truog, William E.; Stevenson, David K.; Van Meurs, Krisa P.; Sánchez, Pablo J.; Das, Abhik; Devaskar, Uday; Nelin, Leif D.; Petrie Huitema, Carolyn M.; Crawford, Margaret M.; Higgins, Rosemary D.

    2016-01-01

    Unpublished results can bias biomedical literature, favoring positive over negative findings, primary over secondary analyses, and can lead to duplicate studies that unnecessarily endanger subjects and waste resources. The Neonatal Research Network’s (NRN) publication policies for approving, reviewing, and tracking abstracts and papers work to combat these problems. In 2003, the NRN restricted investigators with unfinished manuscripts from proposing new ones and in 2010, urged authors to complete long-outstanding manuscripts. Data from 1991 to 2015 were analyzed to determine effectiveness of these policy changes. The NRN has achieved an overall publication rate of 78% for abstracts. For 1990–2002, of 137 abstracts presented, 43 (31%) were published within 2 years; for 2003–2009, after the manuscript completion policy was instituted, of 140 abstracts presented, 68 (49%) were published within 2 years. Following the effort in 2010, the rate increased to 64%. The NRN surpassed reported rates by developing a comprehensive process, holding investigators accountable and tracking abstracts from presentation to publication. PMID:27423510

  9. Wetlands and Paleolakes in the Hyperarid Atacama Desert During the Late Quaternary and Their Implications for Early Human Occupation of South America

    NASA Astrophysics Data System (ADS)

    Pfeiffer, M.; Latorre Hidalgo, C.; Santoro, C.; Gayo, E.; McRostie, V.; Finstad, K. M.; Amundson, R.

    2016-12-01

    The hyperarid Atacama Desert has long been considered a natural barrier to human dispersal. However, several archaeological sites dating from the late Pleistocene have been recently reported on, and other as yet unpublished evidence is rapidly accumulating. It has been established that these occupations were facilitated by increased fluvial activity and biologically productive riparian ecosystems along the western slope of the Andes, and that the presence of humans disappeared with declines in this water flow. The considerable evidence for regional stream flow suggests that basins and lowlands should have contained lakes or wetlands contemporaneous with the ages of the fluvial activity, but there has been no published data on late Quaternary lakes in the region. Here, we report on our observations that possibly many present day salars (salt covered basins) were fresh water lakes and marshlands during the Central Andean Pluvial Event (CAPE) that occurred during the late Pleistocene and early Holocene. We performed radiocarbon analysis of described stratigraphic profiles on paleo-shorelines or in paleo-lake basins that lie within the Pampa del Tamarugal (PDT) basin. We additionally described gastropods, plant remnants, phytoliths and diatomea, which provide a reliable source for paleoenvironmental facies interpretation. These data indicate that a paleolake existed at the location of the present-day Salar de Bellavista, and that wetlands (and possibly lakes) were present at the Salar de Llamara and Pintados. These past aquatic systems are coeval with the activation of the riparian systems of the PDT reported by previous studies. Furthermore, they would have contributed to a starkly different set of resource constraints for early inhabitants than the inhospitable conditions existing today. Additionally, the presence of these water sources provides guidance in the search for additional evidence of human occupation in the region, and for understanding the geographical connections that existed among these earliest inhabitants of the Western Hemisphere.

  10. The Literature of City Magazines.

    ERIC Educational Resources Information Center

    Wiley, Rob

    The research literature on city magazines can be divided into five primary sources: books on magazines, popular magazines/journals and newspapers, business magazines, scholarly journals, and unpublished theses. "The New Yorker," founded in 1925 specifically for a sophisticated, metropolitan audience, is considered a precursor of the…

  11. Neuronal Adaptive Mechanisms Underlying Intelligent Information Processing

    DTIC Science & Technology

    1981-05-01

    Physiol. 134: 451-470, 1956. J. Freud , S, Unpublished, untitled paper (1895) subsequently published in Freud , Sigmund - Standard Edition...of the Complete Psychological Works of Freud , edited by J. Strachey. New York, Macmillan 1: 281-287, 1964. Gallagher, J.P. and Shinnick-Gallagher

  12. 77 FR 11121 - Scientific Information Request on Treatment of Atrial Fibrillation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ... fibrillation medical devices. Scientific information is being solicited to inform our Comparative Effectiveness... unpublished pertinent scientific information on this device will improve the quality of this comparative effectiveness review. AHRQ is requesting this scientific information and conducting this comparative...

  13. BIBLIOGRAPHY ON MENTAL ABILITY.

    ERIC Educational Resources Information Center

    Harvard Univ., Cambridge, MA. Graduate School of Education.

    THIS BIBLIOGRAPHY LISTS MATERIAL ON VARIOUS ASPECTS OF HUMAN INTELLECT. APPROXIMATELY 50 UNANNOTATED REFERENCES ARE PROVIDED TO DOCUMENTS DATING FROM 1955 TO 1966. BOOKS, REPORTS, JOURNAL MATERIALS, AND SOME UNPUBLISHED TITLES ARE LISTED. SUBJECT AREAS INCLUDED ARE (1) INTELLECTUAL DEVELOPMENT, (2) ABILITY DIFFERENCES BETWEEN INDIVIDUALS, RACES,…

  14. BIBLIOGRAPHY ON TEACHING. SUPPLEMENT.

    ERIC Educational Resources Information Center

    Harvard Univ., Cambridge, MA. Graduate School of Education.

    THIS BIBLIOGRAPHY LISTS MATERIAL ON VARIOUS ASPECTS OF TEACHING. APPROXIMATELY 100 UNANNOTATED REFERENCES ARE PROVIDED FOR DOCUMENTS DATING FROM 1960 TO 1966. BOOKS, JOURNALS, REPORT MATERIALS, AND SOME UNPUBLISHED MANUSCRIPTS ARE LISTED IN SUCH AREAS OF EDUCATION AS HEURISTIC GAMES, TEACHER EVALUATION, CURRICULUMS, TEACHING TECHNIQUES, AND…

  15. 21 CFR 99.201 - Manufacturer's submission to the agency.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... dissemination, and unpublished manuscripts, abstracts, and data analyses from completed or ongoing..., completion of data collection, completion of data analysis, and submission of the supplemental application...., the databases or sources and criteria (i.e., subject headings/keywords) used to generate the...

  16. Censorship and Intellectual Freedom: A Bibliography, 1970-1981.

    ERIC Educational Resources Information Center

    Busha, Charles H.

    1982-01-01

    This bibliography contains citations for 94 books and unpublished library science doctoral dissertations, the majority of which pertain to problems in the United States dealing with censorship, intellectual freedom, legal aspects of freedom of expression, and problems associated with obscenity and pornography. (EJS)

  17. Realistic Library Research Methods: Bibliographic Sources Annotated.

    ERIC Educational Resources Information Center

    Kushon, Susan G.; Wells, Bernice

    This guide gives an overview of basic library research methods with emphasis upon developing an understanding of library organization and professional services. Commonly used bibliographic techniques are described for various published and unpublished, print and nonprint materials. Standard reference sources (bibliographies, encyclopedias, annual…

  18. On the correlation of plume centerline velocity decay of turbulent acoustically excited jets

    NASA Technical Reports Server (NTRS)

    Von Glahn, Uwe H.

    1987-01-01

    Acoustic excitation has been shown to alter the velocity decay and spreading characteristics of jet plumes by modifying the large-scale structures in the plume shear layer. The present work consists of reviewing and analyzing available published and unpublished experimental data in order to determine the importance and magnitude of the several variables that contribute to plume modification by acoustic excitation. Included in the study were consideration of the effects of internal or external acoustic excitation, excitation Strouhal number, acoustic excitation level, nozzle size and flow conditions. The last include jet Mach number and jet temperature. The effects of these factors on the plume centerline velocity decay are then summarized in an overall empirical correlation.

  19. VizieR Online Data Catalog: Metal-poor stars towards the Galactic bulge (Koch+, 2016)

    NASA Astrophysics Data System (ADS)

    Koch, A.; McWilliam, A.; Preston, G. W.; Thompson, I. B.

    2015-11-01

    The stars studied here were identified in a search for EMP stars in the Galactic bulge (Preston et al. unpublished), near b=-10°, employing the 2.5-m du Pont and 1-m Swope telescopes at Las Campanas Observatory. Observations of seven EMP candidates presented here were taken spread over six nights in July 2007 with a median seeing of 0.95", while individual exposures reached as high as 2" and notably better conditions (~0.6") during several nights. Our chosen set-up included a 0.5" slit, 2x1 binning in spectral and spatial dimensions and resulted in a resolving power of R~45000. An observing log is given in Table 1. (3 data files).

  20. Placento-Cranial Adhesions in Amniotic Band Syndrome and the Role of Surgery in Their Management: An Unusual Case Presentation and Systematic Literature Review.

    PubMed

    Menekse, Guner; Mert, Mustafa Kurthan; Olmaz, Burak; Celik, Tamer; Celik, Umit Sizmaz; Okten, Ali Ihsan

    2015-01-01

    Amniotic band syndrome is a group of sporadic congenital anomalies that involve the limbs, craniofacial regions and trunk, ranging from simple digital band constriction to complex craniofacial and central nervous system abnormalities. Placento-cranial adhesions in amniotic band syndrome are extremely rare, and severe conditions are associated with high morbidity and mortality rates. In this study, we pooled placento-cranial adhesion case reports that were published in the medical literature and added an unpublished case from our institution. The purpose of this article was to review and discuss the clinical features and outcomes of placento-cranial adhesions in amniotic band syndrome. © 2015 S. Karger AG, Basel.

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