Ikeda, Koki; Koga, Tomoaki; Sasaki, Fumiyuki; Ueno, Ayumi; Saeki, Kazuko; Okuno, Toshiaki; Yokomizo, Takehiko
2017-05-13
DYKDDDDK peptide (FLAG) is a useful tool for investigating the function and localization of proteins whose antibodies (Abs) are not available. We recently established a high-affinity monoclonal antibody (mAb) for FLAG (clone 2H8). The 2H8 Ab is highly sensitive for detecting FLAG-tagged proteins by flowcytometry and immunoprecipitation, but it can yield nonspecific signals in immunohistochemistry of mouse tissues because it is of mouse origin. In this study, we reduced nonspecific signals by generating a chimeric 2H8 Ab with Fc fragments derived from human immunoglobulin. We fused a 5' terminal cDNA fragments for the Fab region of 2H8 mAb with 3' terminal cDNA fragments for Fc region of human IgG1. We transfected both chimeric plasmids and purified the resulting human-mouse chimeric 2H8. The chimeric 2H8 Ab successfully detected FLAG-tagged proteins in flowcytometry with anti-human IgG secondary Ab with comparable sensitivity to 2H8 mAb. Importantly, chimeric 2H8 detected specific FLAG peptide signals without nonspecific signals in immunohistochemical analysis with mouse tissues. This human-mouse chimeric high-affinity anti-FLAG Ab will prove useful for future immunohistochemical analysis of mouse tissues. Copyright © 2017 Elsevier Inc. All rights reserved.
CD109 is a component of exosome secreted from cultured cells
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sakakura, Hiroki; Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Nagoya; Mii, Shinji
Exosomes are 50–100-nm-diameter membrane vesicles released from various types of cells. Exosomes retain proteins, mRNAs and miRNAs, which can be transported to surrounding cells. CD109 is a glycosylphosphatidylinositol-anchored glycoprotein, and is released from the cell surface to the culture medium in vitro. Recently, it was reported that secreted CD109 from the cell surface downregulates transforming growth factor-β signaling in human keratinocytes. In this study, we revealed that CD109 is a component of the exosome in conditioned medium. FLAG-tagged human CD109 (FLAG-CD109) in conditioned medium secreted from HEK293 cells expressing FLAG-CD109 (293/FLAG-CD109) was immunoprecipitated with anti-FLAG affinity gel, and the co-precipitated proteins weremore » analyzed by mass spectrometry and western blotting. Exosomal proteins were associated with CD109. We revealed the presence of CD109 in exosome fractions from conditioned medium of 293/FLAG-CD109. Moreover, the localization of CD109 in the exosome was demonstrated using immuno-electron microscopy. When we used HEK293 cells expressing FLAG-tagged truncated CD109, which does not contain the C-terminal region, the association of truncated CD109 with exosomes was not detected in conditioned medium. These findings indicate that CD109 is an exosomal protein and that the C-terminal region of CD109 is required for its presence in the exosome. - Highlights: • CD109 is an exosomal protein. • The C-terminal region of CD109 is required for its presence in the exosome. • Part of the secreted CD109 is present in the exosome-free fraction in the conditioned medium.« less
General Assembly Governance H Human Development Human Rights I Indigenous Peoples Integral Development Scholarships School of Governance Science and Technology Social Development Summits of the Americas Sustainable (Commonwealth of) Dominica (Commonwealth of) Flag Dominican Republic Dominican Republic Flag Ecuador Ecuador
FlagHouse Forum: You Say "Tomato"... and I Use a Communicator
ERIC Educational Resources Information Center
Exceptional Parent, 2011
2011-01-01
This month's "FlagHouse Forum" focuses on how to choose the communicator best-suited to a child's special need. FlagHouse--a premier global supplier of resources for special needs, education, physical activity and recreation--is pleased to partner with "Exceptional Parent" to bring its readers this informational forum. Humans communicate with each…
Notch as a Diagnostic Marker and Therapeutic Target in Human Breast Cancer
2008-05-01
JAG1. The soluble JAG1-ECD-FLAG was expressed in Chinese Hamster ovary K1 (CHO-K1) cells and then CHO clones were screened for their ability to... medium was collected from CHO-K1- hJAG1-ECD-Flag (clone14) grown in culture. The purification strategy to obtain hJAG1-ECD-Flag is as follows: 1) pre...expressed in Chinese hampster ovary K1 (CHO-K1) cells and then CHO clones were screened for their ability to express high levels of secreted JAG1-Flag
Zhu, Cansheng; Xiong, Zhaojun; Chen, Xiaohong; Lu, Zhengqi; Zhou, Guoyu; Wang, Dunjing; Bao, Jian; Hu, Xueqiang
2011-08-01
We aimed to investigate the regulation and contribution of vascular endothelial growth factor (VEGF) and sFlt-1(1-3) to human monocytic THP-1 migration. Ad-sFlt-1/FLAG, a recombinant adenovirus carrying the human sFlt-1(1-3) (the first three extracellular domains of FLT-1, the hVEGF receptor-1) gene, was constructed. L929 cells were infected with Ad-sFlt-1/FLAG and the expression of sFlt-1 was detected by immunofluorescent assay and ELISA. Corning(®) Transwell(®) Filter Inserts containing polyethylene terephthalate (PET) membranes with pore sizes of 3 μm were used as an experimental model to simulate THP-1 migration. Five VEGF concentrations (0, 0.1, 1, 10 and 100 ng/ml), four concentrations of sFlt-1(1-3)/FLAG expression supernatants (0.1, 1, 10 and 100 ng/ml), and monocyte chemoattractant protein-1 (MCP-1, 10 ng/ml) were used to test the ability of THP-1 cells to migrate through PET membranes. The sFlt-1(1-3) gene was successfully recombined into Ad-sFlt-1/FLAG. sFlt-1(1-3) was expressed in L929 cells transfected with Ad-sFlt-1/FLAG. THP-1 cell migration increased with increasing concentrations of VEGF, while cell migration decreased with increasing concentrations of sFlt1(1-3)/FLAG. sFlt1(1-3)/FLAG had no effect on MCP-1-induced cell migration. This study demonstrated that VEGF is able to elicit a migratory response in THP-1 cells, and that sFlt-1(1-3) is an effective inhibitor of THP-1 migration towards VEGF.
Optimization of mNeonGreen for Homo sapiens increases its fluorescent intensity in mammalian cells.
Tanida-Miyake, Emiko; Koike, Masato; Uchiyama, Yasuo; Tanida, Isei
2018-01-01
Green fluorescent protein (GFP) is tremendously useful for investigating many cellular and intracellular events. The monomeric GFP mNeonGreen is about 3- to 5-times brighter than GFP and monomeric enhanced GFP and shows high photostability. The maturation half-time of mNeonGreen is about 3-fold faster than that of monomeric enhanced GFP. However, the cDNA sequence encoding mNeonGreen contains some codons that are rarely used in Homo sapiens. For better expression of mNeonGreen in human cells, we synthesized a human-optimized cDNA encoding mNeonGreen and generated an expression plasmid for humanized mNeonGreen under the control of the cytomegalovirus promoter. The resultant plasmid was introduced into HEK293 cells. The fluorescent intensity of humanized mNeonGreen was about 1.4-fold higher than that of the original mNeonGreen. The humanized mNeonGreen with a mitochondria-targeting signal showed mitochondrial distribution of mNeonGreen. We further generated an expression vector of humanized mNeonGreen with 3xFLAG tags at its carboxyl terminus as these tags are useful for immunological analyses. The 3xFLAG-tagged mNeonGreen was recognized well with an anti-FLAG-M2 antibody. These plasmids for the expression of humanized mNeonGreen and mNeonGreen-3xFLAG are useful tools for biological studies in mammalian cells using mNeonGreen.
Fraction Flags: Learning from Children to Help Children Learn.
ERIC Educational Resources Information Center
Kieren, Tom; And Others
1996-01-01
Describes "fraction flags", an activity through which fraction concepts can be explored. The activity was invented by 2 12-year-old students and this article is presented with emphasis on the students' viewpoint. It begins with an overview of the fractions unit and presents vignettes of students exploring the fraction flags. (AIM)
Méndez-Hernández, Lucía E; Robledo-Rivera, Angelica Y; Macías-Silva, Marina; Calera, Mónica R; Sánchez-Olea, Roberto
2017-11-01
Gpn1 associates with Gpn3, and both are required for RNA polymerase II nuclear targeting. Global studies have identified by mass spectrometry that human Gpn3 is ubiquitinated on lysines 189 and 216. Our goals here were to determine the type, physiological importance, and regulation of Gpn3 ubiquitination. After inhibiting the proteasome with MG132, Gpn3-Flag was polyubiquitinated on K216, but not K189, in HEK293T cells. Gpn3-Flag exhibited nucleo-cytoplasmic shuttling, but polyubiquitination and proteasomal degradation of Gpn3-Flag occurred only in the cell nucleus. Polyubiquitination-deficient Gpn3-Flag K216R displayed a longer half-life than Gpn3-Flag in two cell lines. Interestingly, Gpn1-EYFP inhibited Gpn3-Flag polyubiquitination in a dose-dependent manner. In conclusion, Gpn1-inhibitable, nuclear polyubiquitination on lysine 216 regulates the half-life of Gpn3 by tagging it for proteasomal degradation. © 2017 Federation of European Biochemical Societies.
3 CFR 8689 - Proclamation 8689 of June 10, 2011. Flag Day and National Flag Week, 2011
Code of Federal Regulations, 2012 CFR
2012-01-01
... America A Proclamation On June 14, 1777, the Second Constitutional Congress adopted a flag with thirteen... were set upon a blue field, in the words of the Congress’s resolution, “representing a new... American flag has been ever present. It has flown on our ships and military bases around the world as we...
Phloem Transport Of Arsenic Species From Flag Leaf To Grain During Grain Filling
Strategies to reduce arsenic (As) in rice grain, below concentrations that represent a serious human health concern, require that the mechanisms of As accumulation within grain be established. Therefore, retranslocation of As species from flag leaves into filling rice grain was ...
Tsze, Daniel S; Ochs, Julie B; Gonzalez, Ariana E; Dayan, Peter S
2018-01-01
Background Clinicians appear to obtain emergent neuroimaging for children with headaches based on the presence of red flag findings. However, little data exists regarding the prevalence of these findings in emergency department populations, and whether the identification of red flag findings is associated with potentially unnecessary emergency department neuroimaging. Objectives We aimed to determine the prevalence of red flag findings and their association with neuroimaging in otherwise healthy children presenting with headaches to the emergency department. Our secondary aim was to determine the prevalence of emergent intracranial abnormalities in this population. Methods A prospective cohort study of otherwise healthy children 2-17 years of age presenting to an urban pediatric emergency department with non-traumatic headaches was undertaken. Emergency department physicians completed a standardized form to document headache descriptors and characteristics, associated symptoms, and physical and neurological exam findings. Children who did not receive emergency department neuroimaging received 4-month telephone follow-up. Outcomes included emergency department neuroimaging and the presence of emergent intracranial abnormalities. Results We enrolled 224 patients; 197 (87.9%) had at least one red flag finding on history. Several red flag findings were reported by more than a third of children, including: Headache waking from sleep (34.8%); headache present with or soon after waking (39.7%); or headaches increasing in frequency, duration and severity (40%, 33.1%, and 46.3%). Thirty-three percent of children received emergency department neuroimaging. The prevalence of emergent intracranial abnormalities was 1% (95% CI 0.1, 3.6). Abnormal neurological exam, extreme pain intensity of presenting headache, vomiting, and positional symptoms were independently associated with emergency department neuroimaging. Conclusions Red flag findings are common in children presenting with headaches to the emergency department. The presence of red flag findings is associated with emergency department neuroimaging, although the risk of emergent intracranial abnormalities is low. Many children with headaches may be receiving unnecessary neuroimaging due to the high prevalence of non-specific red flag findings.
Predictive value of the present-on-admission indicator for hospital-acquired venous thromboembolism.
Khanna, Raman R; Kim, Sharon B; Jenkins, Ian; El-Kareh, Robert; Afsarmanesh, Nasim; Amin, Alpesh; Sand, Heather; Auerbach, Andrew; Chia, Catherine Y; Maynard, Gregory; Romano, Patrick S; White, Richard H
2015-04-01
Hospital-acquired venous thromboembolic (HA-VTE) events are an important, preventable cause of morbidity and death, but accurately identifying HA-VTE events requires labor-intensive chart review. Administrative diagnosis codes and their associated "present-on-admission" (POA) indicator might allow automated identification of HA-VTE events, but only if VTE codes are accurately flagged "not present-on-admission" (POA=N). New codes were introduced in 2009 to improve accuracy. We identified all medical patients with at least 1 VTE "other" discharge diagnosis code from 5 academic medical centers over a 24-month period. We then sampled, within each center, patients with VTE codes flagged POA=N or POA=U (insufficient documentation) and POA=Y or POA=W (timing clinically uncertain) and abstracted each chart to clarify VTE timing. All events that were not clearly POA were classified as HA-VTE. We then calculated predictive values of the POA=N/U flags for HA-VTE and the POA=Y/W flags for non-HA-VTE. Among 2070 cases with at least 1 "other" VTE code, we found 339 codes flagged POA=N/U and 1941 flagged POA=Y/W. Among 275 POA=N/U abstracted codes, 75.6% (95% CI, 70.1%-80.6%) were HA-VTE; among 291 POA=Y/W abstracted events, 73.5% (95% CI, 68.0%-78.5%) were non-HA-VTE. Extrapolating from this sample, we estimated that 59% of actual HA-VTE codes were incorrectly flagged POA=Y/W. POA indicator predictive values did not improve after new codes were introduced in 2009. The predictive value of VTE events flagged POA=N/U for HA-VTE was 75%. However, sole reliance on this flag may substantially underestimate the incidence of HA-VTE.
Grainger, Jonathan; Declerck, Mathieu; Marzouki, Yousri
2017-07-01
French-English bilinguals performed a generalized lexical decision experiment with mixed lists of French and English words and pseudo-words. In Experiment 1, each word/pseudo-word was superimposed on the picture of the French or UK flag, and flag-word congruency was manipulated. The flag was not informative with respect to either the lexical decision response or the language of the word. Nevertheless, lexical decisions to word stimuli were faster following the congruent flag compared with the incongruent flag, but only for French (L1) words. Experiment 2 replicated this flag-language congruency effect in a priming paradigm, where the word and pseudo-word targets followed the brief presentation of the flag prime, and this time effects were seen in both languages. We take these findings as evidence for a mechanism that automatically processes linguistic and non-linguistic information concerning the presence or not of a given language. Language membership information can then modulate lexical processing, in line with the architecture of the BIA model, but not the BIA+ model. Copyright © 2017 Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rockel, Beate; Schmaler, Tilo; Huang, Xiaohua
2014-07-25
Highlights: • Deneddylation rates of human erythrocyte and mouse fibroblast CSN are very similar. • 3D models of native human and mouse CSN reveal common architectures. • The cryo-structure of native mammalian CSN shows a horseshoe subunit arrangement. - Abstract: The COP9 signalosome (CSN) is a regulator of the ubiquitin (Ub) proteasome system (UPS). In the UPS, proteins are Ub-labeled for degradation by Ub ligases conferring substrate specificity. The CSN controls a large family of Ub ligases called cullin-RING ligases (CRLs), which ubiquitinate cell cycle regulators, transcription factors and DNA damage response proteins. The CSN possesses structural similarities with themore » 26S proteasome Lid complex and the translation initiation complex 3 (eIF3) indicating similar ancestry and function. Initial structures were obtained 14 years ago by 2D electron microscopy (EM). Recently, first 3D molecular models of the CSN were created on the basis of negative-stain EM and single-particle analysis, mostly with recombinant complexes. Here, we compare deneddylating activity and structural features of CSN complexes purified in an elaborate procedure from human erythrocytes and efficiently pulled down from mouse Flag-CSN2 B8 fibroblasts. In an in vitro deneddylation assay both the human and the mouse CSN complexes deneddylated Nedd8-Cul1 with comparable rates. 3D structural models of the erythrocyte CSN as well as of the mouse Flag-CSN were generated by negative stain EM and by cryo-EM. Both complexes show a central U-shaped segment from which several arms emanate. This structure, called the horseshoe, is formed by the PCI domain subunits. CSN5 and CSN6 point away from the horseshoe. Compared to 3D models of negatively stained CSN complexes, densities assigned to CSN2 and CSN4 are better defined in the cryo-map. Because biochemical and structural results obtained with CSN complexes isolated from human erythrocytes and purified by Flag-CSN pulldown from mouse B8 fibroblasts are very similar, Flag-CSN pulldowns are a proper alternative to CSN preparation from erythrocytes.« less
Flagging versus dragging as sampling methods for nymphal Ixodes scapularis (Acari: Ixodidae)
Rulison, Eric L.; Kuczaj, Isis; Pang, Genevieve; Hickling, Graham J.; Tsao, Jean I.; Ginsberg, Howard S.
2013-01-01
The nymphal stage of the blacklegged tick, Ixodes scapularis (Acari: Ixodidae), is responsible for most transmission of Borrelia burgdorferi, the etiologic agent of Lyme disease, to humans in North America. From 2010 to fall of 2012, we compared two commonly used techniques, flagging and dragging, as sampling methods for nymphal I. scapularis at three sites, each with multiple sampling arrays (grids), in the eastern and central United States. Flagging and dragging collected comparable numbers of nymphs, with no consistent differences between methods. Dragging collected more nymphs than flagging in some samples, but these differences were not consistent among sites or sampling years. The ratio of nymphs collected by flagging vs dragging was not significantly related to shrub density, so habitat type did not have a strong effect on the relative efficacy of these methods. Therefore, although dragging collected more ticks in a few cases, the numbers collected by each method were so variable that neither technique had a clear advantage for sampling nymphal I. scapularis.
NASA Astrophysics Data System (ADS)
Sturtevant, C.; Hackley, S.; Lee, R.; Holling, G.; Bonarrigo, S.
2017-12-01
Quality assurance and control (QA/QC) is one of the most important yet challenging aspects of producing research-quality data. Data quality issues are multi-faceted, including sensor malfunctions, unmet theoretical assumptions, and measurement interference from humans or the natural environment. Tower networks such as Ameriflux, ICOS, and NEON continue to grow in size and sophistication, yet tools for robust, efficient, scalable QA/QC have lagged. Quality control remains a largely manual process heavily relying on visual inspection of data. In addition, notes of measurement interference are often recorded on paper without an explicit pathway to data flagging. As such, an increase in network size requires a near-proportional increase in personnel devoted to QA/QC, quickly stressing the human resources available. We present a scalable QA/QC framework in development for NEON that combines the efficiency and standardization of automated checks with the power and flexibility of human review. This framework includes fast-response monitoring of sensor health, a mobile application for electronically recording maintenance activities, traditional point-based automated quality flagging, and continuous monitoring of quality outcomes and longer-term holistic evaluations. This framework maintains the traceability of quality information along the entirety of the data generation pipeline, and explicitly links field reports of measurement interference to quality flagging. Preliminary results show that data quality can be effectively monitored and managed for a multitude of sites with a small group of QA/QC staff. Several components of this framework are open-source, including a R-Shiny application for efficiently monitoring, synthesizing, and investigating data quality issues.
76 FR 35087 - Flag Day and National Flag Week, 2011
Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-15
... United States of America A Proclamation On June 14, 1777, the Second Constitutional Congress adopted a... founding colonies. The stars were set upon a blue field, in the words of the Congress's resolution... faced, the American flag has been ever present. It has flown on our ships and military bases around the...
RFI flagging implications for short-duration transients
NASA Astrophysics Data System (ADS)
Cendes, Y.; Prasad, P.; Rowlinson, A.; Wijers, R. A. M. J.; Swinbank, J. D.; Law, C. J.; van der Horst, A. J.; Carbone, D.; Broderick, J. W.; Staley, T. D.; Stewart, A. J.; Huizinga, F.; Molenaar, G.; Alexov, A.; Bell, M. E.; Coenen, T.; Corbel, S.; Eislöffel, J.; Fender, R.; Grießmeier, J.-M.; Jonker, P.; Kramer, M.; Kuniyoshi, M.; Pietka, M.; Stappers, B.; Wise, M.; Zarka, P.
2018-04-01
With their wide fields of view and often relatively long coverage of any position in the sky in imaging survey mode, modern radio telescopes provide a data stream that is naturally suited to searching for rare transients. However, Radio Frequency Interference (RFI) can show up in the data stream in similar ways to such transients, and thus the normal pre-treatment of filtering RFI (flagging) may also remove astrophysical transients from the data stream before imaging. In this paper we investigate how standard flagging affects the detectability of such transients by examining the case of transient detection in an observing mode used for Low Frequency Array (LOFAR; van Haarlem et al., 2013) surveys. We quantify the fluence range of transients that would be detected, and the reduction of their SNR due to partial flagging. We find that transients with a duration close to the integration sampling time, as well as bright transients with durations on the order of tens of seconds, are completely flagged. For longer transients on the order of several tens of seconds to minutes, the flagging effects are not as severe, although part of the signal is lost. For these transients, we present a modified flagging strategy which mitigates the effect of flagging on transient signals. We also present a script which uses the differences between the two strategies, and known differences between transient RFI and astrophysical transients, to notify the observer when a potential transient is in the data stream.
Defense.gov - Special Report: Travels with Panetta
Flag of Japan Japan Flag of China China Flag of New Zealand New Zealand Top Stories Secretary Honors Past, Present New Zealand Troops Defense Secretary Leon E. Panetta placed a wreath in memory of New Memorial Museum. Story Panetta Eases Restrictions on New Zealand Ship Visits Defense Secretary Leon E
Premkumar, Ajay; Godfrey, William; Gottschalk, Michael B; Boden, Scott D
2018-03-07
Low back pain has a high prevalence and morbidity, and is a source of substantial health-care spending. Numerous published guidelines support the use of so-called red flag questions to screen for serious pathology in patients with low back pain. This paper examines the effectiveness of red flag questions as a screening tool for patients presenting with low back pain to a multidisciplinary academic spine center. We conducted a retrospective review of the cases of 9,940 patients with a chief complaint of low back pain. The patients completed a questionnaire that included several red flag questions during their first physician visit. Diagnostic data for the same clinical episode were collected from medical records and were corroborated with imaging reports. Patients who were diagnosed as having a vertebral fracture, malignancy, infection, or cauda equina syndrome were classified as having a red flag diagnosis. Specific individual red flags and combinations of red flags were associated with an increased probability of underlying serious spinal pathology, e.g., recent trauma and an age of >50 years were associated with vertebral fracture. The presence or absence of other red flags, such as night pain, was unrelated to any particular diagnosis. For instance, for patients with no recent history of infection and no fever, chills, or sweating, the presence of night pain was a false-positive finding for infection >96% of the time. In general, the absence of red flag responses did not meaningfully decrease the likelihood of a red flag diagnosis; 64% of patients with spinal malignancy had no associated red flags. While a positive response to a red flag question may indicate the presence of serious disease, a negative response to 1 or 2 red flag questions does not meaningfully decrease the likelihood of a red flag diagnosis. Clinicians should use caution when utilizing red flag questions as screening tools.
Parravano, Antonio; Noguera, José A.; Hermida, Paula; Tena-Sánchez, Jordi
2015-01-01
Models of social influence have explored the dynamics of social contagion, imitation, and diffusion of different types of traits, opinions, and conducts. However, few behavioral data indicating social influence dynamics have been obtained from direct observation in “natural” social contexts. The present research provides that kind of evidence in the case of the public expression of political preferences in the city of Barcelona, where thousands of citizens supporting the secession of Catalonia from Spain have placed a Catalan flag in their balconies and windows. Here we present two different studies. 1) During July 2013 we registered the number of flags in 26% of the electoral districts in the city of Barcelona. We find that there is a large dispersion in the density of flags in districts with similar density of pro-independence voters. However, by comparing the moving average to the global mean we find that the density of flags tends to be fostered in electoral districts where there is a clear majority of pro-independence vote, while it is inhibited in the opposite cases. We also show that the distribution of flags in the observed districts deviates significantly from that of an equivalent random distribution. 2) During 17 days around Catalonia’s 2013 national holiday we observed the position at balcony resolution of the flags displayed in the facades of a sub-sample of 82 blocks. We compare the ‘clustering index’ of flags on the facades observed each day to thousands of equivalent random distributions. Again we provide evidence that successive hangings of flags are not independent events but that a local influence mechanism is favoring their clustering. We also find that except for the national holiday day the density of flags tends to be fostered in facades located in electoral districts where there is a clear majority of pro-independence vote. PMID:25961562
No Global Citizenship? Re-Envisioning Global Citizenship Education in Times of Growing Nationalism
ERIC Educational Resources Information Center
Barrow, Elizabeth
2017-01-01
This article presents a discussion of the author's concern over a statement President Trump made in his first Thank You Tour speech, given Dec 1, 2016, in Cincinnati Ohio. "There is no global anthem. No global currency. No certificate of global citizenship. We pledge allegiance to one flag and that flag is the American flag." Here…
Flag-based detection of weak gas signatures in long-wave infrared hyperspectral image sequences
NASA Astrophysics Data System (ADS)
Marrinan, Timothy; Beveridge, J. Ross; Draper, Bruce; Kirby, Michael; Peterson, Chris
2016-05-01
We present a flag manifold based method for detecting chemical plumes in long-wave infrared hyperspectral movies. The method encodes temporal and spatial information related to a hyperspectral pixel into a flag, or nested sequence of linear subspaces. The technique used to create the flags pushes information about the background clutter, ambient conditions, and potential chemical agents into the leading elements of the flags. Exploiting this temporal information allows for a detection algorithm that is sensitive to the presence of weak signals. This method is compared to existing techniques qualitatively on real data and quantitatively on synthetic data to show that the flag-based algorithm consistently performs better on data when the SINRdB is low, and beats the ACE and MF algorithms in probability of detection for low probabilities of false alarm even when the SINRdB is high.
The Savannah River Site`s Groundwater Monitoring Program. Second quarter, 1991
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1992-01-10
The Environmental Protection Department/Environmental Monitoring Section (EPD/EMS) administers the Savannah River Site`s (SRS) Groundwater Monitoring Program. During second quarter 1991 EPD/EMS conducted extensive sampling of monitoring wells. EPD/EMS established two sets of flagging criteria in 1986 to assist in the management of sample results. The flagging criteria do not define contamination levels; instead, they aid personnel in sample scheduling, interpretation of data, and trend identification. Beginning in 1991, the flagging criteria are based on EPA drinking water standards and method detection limits. A detailed explanation of the current flagging criteria is presented in the Flagging Criteria section of this document.more » Analytical results from second quarter 1991 are listed in this report.« less
The Savannah River Site's Groundwater Monitoring Program
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1992-01-10
The Environmental Protection Department/Environmental Monitoring Section (EPD/EMS) administers the Savannah River Site's (SRS) Groundwater Monitoring Program. During second quarter 1991 EPD/EMS conducted extensive sampling of monitoring wells. EPD/EMS established two sets of flagging criteria in 1986 to assist in the management of sample results. The flagging criteria do not define contamination levels; instead, they aid personnel in sample scheduling, interpretation of data, and trend identification. Beginning in 1991, the flagging criteria are based on EPA drinking water standards and method detection limits. A detailed explanation of the current flagging criteria is presented in the Flagging Criteria section of this document.more » Analytical results from second quarter 1991 are listed in this report.« less
Human Subjects Research and the Physics Classroom
NASA Astrophysics Data System (ADS)
Kubitskey, Beth W.; Thomsen, Marshall
2012-09-01
Physics Education Research is a form of social science research in that it uses human subjects. As physicists we need to be aware of the ethical and legal ramifications of performing this research, taking into account the fundamental differences between working with substances and working with people. For several decades, the federal government has regulated research involving human subjects. With current procedures, a proposal soliciting federal funds for a research project involving human subjects will be flagged by the applicants institution and checked for compliance with appropriate regulations. However, there is a large body of Physics Education Research that is not federally funded and thus may not be flagged. Nevertheless, there are ethical standards that apply to this research. This paper outlines the preliminary considerations for conducting such research.
Griffin, Michael J
2015-01-01
At work or in leisure activities, many people are exposed to vibration or mechanical shocks associated with risks of injury or disease. This paper identifies information that can be used to decide whether there may be a risk from exposure to hand-transmitted vibration or whole-body vibration and shock, and suggests actions that can control the risks. The complex and time-varying nature of human exposures to vibration and shock, the complexity of the different disorders and uncertainty as to the mechanisms of injury and the factors influencing injury have prevented the definition of dose-response relationships well proven by scientific study. It is necessary to wave a flag indicating when there is a need to control risks from exposure to vibration and shock while scientific enquiry provides understanding needed to weave a better flag. It is concluded that quantifying exposure severity is often neither necessary nor sufficient to either identify risks or implement measures that control the risks. The identification of risks associated with exposure to vibration and mechanical shock cannot, and need not, rely solely on the quantification of exposure severity. Qualitative methods can provide a sufficient indication of the need for control measures, which should not be restricted to reducing standardised measures of exposure severity.
Endometase in Androgen-Repressed Human Prostate Cancer
2005-03-01
immunosorbent assay (ELISA) and immunoblot using enhanced chemiluminescence (ECL). There are four specific endometase antibodies (Abs) available at the...lysates were An~t-FLAG-MJ2 analyzed by Western blotting using anti- FLAG-M2 antibody . Parental WT-MMP-26 EA-MMP-26 Parental (+YHJ-132) 100 125 54 51...invasion by MMP-26 antibodies is not due to the effects of the antibodies on cell attachment to extracellular matrix, cell proliferation, cytotoxicity
Utilising flags to reduce drag around a short finite circular cylinder
NASA Astrophysics Data System (ADS)
Javadi, Kh.; Kiani, F.; Tahaye Abadi, M.
2018-03-01
This paper utilises flags to decrease the drag around a short finite circular cylinder. Wall-adapted large eddy simulation and two-way fluid-structure interaction methods were applied to resolve unsteady turbulent flow structure. The far-field Reynolds number of the current configuration based on the cylinder diameter was chosen to be 20,000. In addition, the length-to-diameter ratio of the cylinder was assumed to be L/D = 2 whereas the flexible flag had a width-to-diameter ratio of W/D = 1.5. The results were compared with the regular short finite circular cylinder and the rigid flagged cylinder in our previous work. The results indicate that utilising flags inside the near-wake region of the cylinder reduces the pressure drag. The physical mechanism of this drag reduction is presented.
Department of Defense: Electronic Biometric Transmission Specification. Version 2.0
2009-03-27
Abstractions = ABSTRACT Insignias & Symbols = SYMBOL Other Images = OTHER Information Item Number: 3 Tattoo Subclass Description: This information item...Tattoo Subclasses: American Flag = USA State Flag = STATE Nazi Flag = NAZI Confederate Flag = CONFED British Flag = BRIT Miscellaneous Flags = MFLAG...Vegetables = MPLANT Flag Tattoo Subclasses: American Flag = USA State Flag = STATE Nazi Flag = NAZI Confederate Flag = CONFED British Flag = BRIT
Deciphering the Molecular Mechanisms of Breast Cancer
2005-03-01
2007). Nicolas E., Lee M.G., Hakimi M.A., Cam H.P., Grewal S.I., Shiekhattar R. Fussion yeast homologs of human H3 lysinee 4 demethylase regulate a...Baillat D., Hakimi M.A., Naar A., Shilatifard A., Cooch N., Shiekhattar R. Integrator, a multiprotein mediator of small nuclear RNA processing...fractionof FLAG-BARD1 using anti-FLAG antibodies from H1299 of BRCA1 and BARD1 elute at a smaller molecular masscells. Nuclear extract from native H1299
Dobson, Andrew D M; Taylor, Jennifer L; Randolph, Sarah E
2011-06-01
The seasonal risk to humans of picking up Ixodes ricinus ticks in different habitats at 3 recreational sites in the UK was assessed. A comprehensive range of vegetation types was sampled at 3-weekly intervals for 2 years, using standard blanket-dragging complemented by woollen leggings and square 'heel flags'. Ticks were found in all vegetation types sampled, including short grass close to car parks, but highest densities were consistently found in plots with trees present. Blankets picked up the greatest number of ticks, but heel flags provided important complementary counts of the immature stages in bracken plots; they showed clearly that the decline in tick numbers on blankets in early summer was due to the seasonal growth of vegetation that lifted the blanket clear of the typical questing height, but in reality ticks remained abundant through the summer. Leggings picked up only 11% of the total nymphs and 22% of total adults counted, but this still represented a significant hazard to humans. These results should prompt a greater awareness of the fine-scale distribution of this species in relation to human activities that determines the most likely zones of contact between humans and ticks. Risk communication may then be designed accordingly. Copyright © 2011 Elsevier GmbH. All rights reserved.
The Savannah River Site`s Groundwater Monitoring Program, first quarter 1989
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
The Environmental Monitoring Section of the Environmental and Health Protection (EHP) Department administers the Savannah River Site`s Groundwater Monitoring Program. During first quarter 1989 (January--March), EHP conducted routine sampling of monitoring wells and drinking water locations. EHP collected the drinking water samples from Savannah River Site (SRS) drinking water systems supplied by wells. EHP established two sets of flagging criteria in 1986 to assist in the management of sample results. The flagging criteria aid personnel in sample scheduling, interpretation of data, and trend identification. The flagging criteria are based on detection limits, background levels in SRS groundwater, and drinking watermore » standards. An explanation of flagging criteria for the first quarter is presented in the Flagging Criteria section of this document. All analytical results from first quarter 1989 are listed in this report, which is distributed to all waste-site custodians.« less
The Savannah River Site`s Groundwater Monitoring Program, third quarter 1989
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
The Environmental Monitoring Section of the Environmental and Health Protection (EHP) Department administers the Savannah River Site`s Groundwater Monitoring Program. During third quarter 1989 (July--September), EHP conducted routine sampling of monitoring wells and drinking water locations. EHP collected the drinking water samples from Savannah River Site (SRS) drinking water systems supplied by wells. EHP established two sets of flagging criteria in 1986 to assist in the management of sample results. The flagging criteria do not define contamination levels; instead they aid personnel in sample scheduling, interpretation of data, and trend identification. The flagging criteria are based on detection limits, backgroundmore » levels in SRS groundwater, and drinking water standards. An explanation of flagging criteria for the third quarter is presented in the Flagging Criteria section of this document. All analytical results from third quarter 1989 are listed in this report, which is distributed to all waste-site custodians.« less
The Savannah River Site's Groundwater Monitoring Program, third quarter 1989
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
The Environmental Monitoring Section of the Environmental and Health Protection (EHP) Department administers the Savannah River Site's Groundwater Monitoring Program. During third quarter 1989 (July--September), EHP conducted routine sampling of monitoring wells and drinking water locations. EHP collected the drinking water samples from Savannah River Site (SRS) drinking water systems supplied by wells. EHP established two sets of flagging criteria in 1986 to assist in the management of sample results. The flagging criteria do not define contamination levels; instead they aid personnel in sample scheduling, interpretation of data, and trend identification. The flagging criteria are based on detection limits, backgroundmore » levels in SRS groundwater, and drinking water standards. An explanation of flagging criteria for the third quarter is presented in the Flagging Criteria section of this document. All analytical results from third quarter 1989 are listed in this report, which is distributed to all waste-site custodians.« less
The Savannah River Site's Groundwater Monitoring Program, first quarter 1989
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
The Environmental Monitoring Section of the Environmental and Health Protection (EHP) Department administers the Savannah River Site's Groundwater Monitoring Program. During first quarter 1989 (January--March), EHP conducted routine sampling of monitoring wells and drinking water locations. EHP collected the drinking water samples from Savannah River Site (SRS) drinking water systems supplied by wells. EHP established two sets of flagging criteria in 1986 to assist in the management of sample results. The flagging criteria aid personnel in sample scheduling, interpretation of data, and trend identification. The flagging criteria are based on detection limits, background levels in SRS groundwater, and drinking watermore » standards. An explanation of flagging criteria for the first quarter is presented in the Flagging Criteria section of this document. All analytical results from first quarter 1989 are listed in this report, which is distributed to all waste-site custodians.« less
The Savannah River Site's Groundwater Monitoring Program: Second quarter 1992
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rogers, C.D.
1992-10-07
The Environmental Protection Department/Environmental Monitoring Section (EPD/EMS) administers the Savannah River Site's (SRS) Groundwater Monitoring Program. During second quarter 1992, EPD/EMS conducted extensive sampling of monitoring wells. EPD/EMS established two sets of criteria to assist in the management of sample results. The flagging criteria do not define contamination levels; instead, they aid personnel in sample scheduling, interpretation of data, and trend identification. Since 1991, the flagging criteria have been based on the federal Environmental Protection Agency (EPA) drinking water standards and on method detection limits. A detailed explanation of the current flagging criteria is presented in the Flagging Criteria sectionmore » of this document. Analytical results from second quarter 1992 are listed in this report.« less
Kaspers, Gertjan J L; Zimmermann, Martin; Reinhardt, Dirk; Gibson, Brenda E S; Tamminga, Rienk Y J; Aleinikova, Olga; Armendariz, Hortensia; Dworzak, Michael; Ha, Shau-Yin; Hasle, Henrik; Hovi, Liisa; Maschan, Alexei; Bertrand, Yves; Leverger, Guy G; Razzouk, Bassem I; Rizzari, Carmelo; Smisek, Petr; Smith, Owen; Stark, Batia; Creutzig, Ursula
2013-02-10
In pediatric relapsed acute myeloid leukemia (AML), optimal reinduction therapy is unknown. Studies suggest that liposomal daunorubicin (DNX; DaunoXome; Galen, Craigavon, United Kingdom) is effective and less cardiotoxic, which is important in this setting. These considerations led to a randomized phase III study by the International Berlin-Frankfurt-Münster Study Group. Patients with relapsed or primary refractory non-French-American-British type M3 AML who were younger than 21 years of age were eligible. Patients were randomly assigned to fludarabine, cytarabine, and granulocyte colony-stimulating factor (FLAG) or to FLAG plus DNX in the first reinduction course. The primary end point was status of the bone marrow (BM) sampled shortly before the second course of chemotherapy (the day 28 BM). Data are presented according to intention-to-treat for all 394 randomly assigned patients (median follow-up, 4.0 years). The complete remission (CR) rate was 64%, and the 4-year probability of survival (pOS) was 38% (SE, 3%). The day 28 BM status (available in 359 patients) was good (≤ 20% leukemic blasts) in 80% of patients randomly assigned to FLAG/DNX and 70% for patients randomly assigned to FLAG (P = .04). Concerning secondary end points, the CR rate was 69% with FLAG/DNX and 59% with FLAG (P = .07), but overall survival was similar. However, core-binding factor (CBF) AML treated with FLAG/DNX resulted in pOS of 82% versus 58% with FLAG (P = .04). Grade 3 to 4 toxicity was essentially similar in both groups. DNX added to FLAG improves early treatment response in pediatric relapsed AML. Overall long-term survival was similar, but CBF-AML showed an improved survival with FLAG/DNX. International collaboration proved feasible and resulted in the best outcome for pediatric relapsed AML reported thus far.
Barunawati, Nunun; Giehl, Ricardo F Hettwer; Bauer, Bernhard; von Wirén, Nicolaus
2013-01-01
The fortification of cereal grains with metal micronutrients is a major target to combat human malnutrition of Fe and Zn. Based on recent studies showing that N fertilization can promote Fe and Zn accumulation in cereal grains, we investigated here the influence of nitrate- or ammonium-based N fertilization on the accumulation of Fe, Zn, and Cu as well as metal chelator pools in flag leaves and grains of winter wheat. Fertilization with either N form increased the concentrations of N and of the metal chelator nicotianamine (NA) in green leaves, while 2'-deoxymugineic acid (DMA) remained unaffected. Despite the differential response to N fertilization of NA and DMA levels in flag leaves, N fertilization remained without any significant effect on the net export of these metals during flag leaf senescence, which accounted for approximately one third of the total Fe, Zn, or Cu content in leaves. The significant increase in the accumulation of Fe, Zn, and Cu found in the grains of primarily ammonium-fertilized plants was unrelated to the extent of metal retranslocation from flag leaves. These results indicate that an increased N nutritional status of flag leaves promotes the accumulation of Fe, Zn, and Cu in flag leaves, which is accompanied by an increased pool of NA but not of DMA. With regard to the far higher concentrations of DMA relative to NA in leaves and leaf exudates, DMA may be more relevant for the mobilization and retranslocation of these metals in high-yielding wheat production.
(U) A Gruneisen Equation of State for TPX. Application in FLAG
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fredenburg, David A.; Aslam, Tariq Dennis; Bennett, Langdon Stanford
2015-11-02
A Gruneisen equation of state (EOS) is developed for the polymer TPX (poly 4-methyl-1-pentene) within the LANL hydrocode FLAG. Experimental shock Hugoniot data for TPX is fit to a form of the Gruneisen EOS, and the necessary parameters for implementing the TPX EOS in FLAG are presented. The TPX EOS is further validated through one-dimensional simulations of recent double-shock experiments, and a comparison is made between the new Gruneisen EOS for TPX and the EOS representation for TPX used in the LANL Common Model.
Bender, Brian J; Coen, Donald M; Strang, Blair L
2014-10-01
Protein-protein and protein-nucleic acid interactions within subcellular compartments are required for viral genome replication. To understand the localization of the human cytomegalovirus viral replication factor UL84 relative to other proteins involved in viral DNA synthesis and to replicating viral DNA in infected cells, we created a recombinant virus expressing a FLAG-tagged version of UL84 (UL84FLAG) and used this virus in immunofluorescence assays. UL84FLAG localization differed at early and late times of infection, transitioning from diffuse distribution throughout the nucleus to exclusion from the interior of replication compartments, with some concentration at the periphery of replication compartments with newly labeled DNA and the viral DNA polymerase subunit UL44. Early in infection, UL84FLAG colocalized with the viral single-stranded DNA binding protein UL57, but colocalization became less prominent as infection progressed. A portion of UL84FLAG also colocalized with the host nucleolar protein nucleolin at the peripheries of both replication compartments and nucleoli. Small interfering RNA (siRNA)-mediated knockdown of nucleolin resulted in a dramatic elimination of UL84FLAG from replication compartments and other parts of the nucleus and its accumulation in the cytoplasm. Reciprocal coimmunoprecipitation of viral proteins from infected cell lysates revealed association of UL84, UL44, and nucleolin. These results indicate that UL84 localization during infection is dynamic, which is likely relevant to its functions, and suggest that its nuclear and subnuclear localization is highly dependent on direct or indirect interactions with nucleolin. Importance: The protein-protein interactions among viral and cellular proteins required for replication of the human cytomegalovirus (HCMV) DNA genome are poorly understood. We sought to understand how an enigmatic HCMV protein critical for virus replication, UL84, localizes relative to other viral and cellular proteins required for HCMV genome replication and replicating viral DNA. We found that UL84 localizes with viral proteins, viral DNA, and the cellular nucleolar protein nucleolin in the subnuclear replication compartments in which viral DNA replication occurs. Unexpectedly, we also found localization of UL84 with nucleolin in nucleoli and showed that the presence of nucleolin is involved in localization of UL84 to the nucleus. These results add to previous work showing the importance of nucleolin in replication compartment architecture and viral DNA synthesis and are relevant to understanding UL84 function. Copyright © 2014, American Society for Microbiology. All Rights Reserved.
The Savannah River Site's Groundwater Monitoring Program
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1989-01-01
The Environmental Monitoring Section of the Environmental and Health Protection (EHP) Department administers the Savannah River Site's Groundwater Monitoring Program. During fourth quarter 1989 (October--December), EHP conducted routine sampling of monitoring wells and drinking water locations. EHP collected the drinking water samples from Savannah River Site (SRS) drinking water systems supplied by wells. EHP established two sets of flagging criteria in 1986 to assist in the management of sample results. The flagging criteria aid personnel in sample scheduling, interpretation of data, and trend identification. An explanation of flagging criteria for the fourth quarter is presented in the Flagging Criteria sectionmore » of this document. All analytical results from fourth quarter 1989 are listed in this report, which is distributed to all waste-site custodians.« less
The Savannah River Site`s Groundwater Monitoring Program. Fourth quarter, 1989
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1989-12-31
The Environmental Monitoring Section of the Environmental and Health Protection (EHP) Department administers the Savannah River Site`s Groundwater Monitoring Program. During fourth quarter 1989 (October--December), EHP conducted routine sampling of monitoring wells and drinking water locations. EHP collected the drinking water samples from Savannah River Site (SRS) drinking water systems supplied by wells. EHP established two sets of flagging criteria in 1986 to assist in the management of sample results. The flagging criteria aid personnel in sample scheduling, interpretation of data, and trend identification. An explanation of flagging criteria for the fourth quarter is presented in the Flagging Criteria sectionmore » of this document. All analytical results from fourth quarter 1989 are listed in this report, which is distributed to all waste-site custodians.« less
A Preliminary Assessment of the SURF Reactive Burn Model Implementation in FLAG
DOE Office of Scientific and Technical Information (OSTI.GOV)
Johnson, Carl Edward; McCombe, Ryan Patrick; Carver, Kyle
Properly validated and calibrated reactive burn models (RBM) can be useful engineering tools for assessing high explosive performance and safety. Experiments with high explosives are expensive. Inexpensive RBM calculations are increasingly relied on for predictive analysis for performance and safety. This report discusses the validation of Menikoff and Shaw’s SURF reactive burn model, which has recently been implemented in the FLAG code. The LANL Gapstick experiment is discussed as is its’ utility in reactive burn model validation. Data obtained from pRad for the LT-63 series is also presented along with FLAG simulations using SURF for both PBX 9501 and PBXmore » 9502. Calibration parameters for both explosives are presented.« less
15 CFR 971.701 - Criteria for safety of life and property at sea.
Code of Federal Regulations, 2010 CFR
2010-01-01
... REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR COMMERCIAL RECOVERY PERMITS... by present laws and regulations. The primary inspection statutes pertaining to United States flag... Motor Vessels, and Freight Vessels). United States flag vessels will be required to meet all applicable...
Tobinaga, Shuichi; Matsumoto, Keitaro; Nagayasu, Takeshi; Furukawa, Katsuro; Abo, Takafumi; Yamasaki, Naoya; Tsuchiya, Tomoshi; Miyazaki, Takuro; Koji, Takehiko
2015-06-29
Pulmonary emphysema is a progressive disease with airspace destruction and an effective therapy is needed. Keratinocyte growth factor (KGF) promotes pulmonary epithelial proliferation and has the potential to induce lung regeneration. The aim of this study was to determine the possibility of using KGF gene therapy for treatment of a mouse emphysema model induced by porcine pancreatic elastase (PPE). Eight-week-old BALB/c male mice treated with intra-tracheal PPE administration were transfected with 80 μg of a recombinant human KGF (rhKGF)-expressing FLAG-CMV14 plasmid (pKGF-FLAG gene), or with the pFLAG gene expressing plasmid as a control, into the quadriceps muscle by electroporation. In the lung, the expression of proliferating cell nuclear antigen (PCNA) was augmented, and surfactant protein A (SP-A) and KGF receptor (KGFR) were co-expressed in PCNA-positive cells. Moreover, endogenous KGF and KGFR gene expression increased significantly by pKGF-FLAG gene transfection. Arterial blood gas analysis revealed that the PaO2 level was not significantly reduced on day 14 after PPE instillation with pKGF-FLAG gene transfection compared to that of normal mice. These results indicated that KGF gene therapy with electroporation stimulated lung epithelial proliferation and protected depression of pulmonary function in a mouse emphysema model, suggesting a possible method of treating pulmonary emphysema.
Tobinaga, Shuichi; Matsumoto, Keitaro; Nagayasu, Takeshi; Furukawa, Katsuro; Abo, Takafumi; Yamasaki, Naoya; Tsuchiya, Tomoshi; Miyazaki, Takuro; Koji, Takehiko
2015-01-01
Pulmonary emphysema is a progressive disease with airspace destruction and an effective therapy is needed. Keratinocyte growth factor (KGF) promotes pulmonary epithelial proliferation and has the potential to induce lung regeneration. The aim of this study was to determine the possibility of using KGF gene therapy for treatment of a mouse emphysema model induced by porcine pancreatic elastase (PPE). Eight-week-old BALB/c male mice treated with intra-tracheal PPE administration were transfected with 80 μg of a recombinant human KGF (rhKGF)-expressing FLAG-CMV14 plasmid (pKGF-FLAG gene), or with the pFLAG gene expressing plasmid as a control, into the quadriceps muscle by electroporation. In the lung, the expression of proliferating cell nuclear antigen (PCNA) was augmented, and surfactant protein A (SP-A) and KGF receptor (KGFR) were co-expressed in PCNA-positive cells. Moreover, endogenous KGF and KGFR gene expression increased significantly by pKGF-FLAG gene transfection. Arterial blood gas analysis revealed that the PaO2 level was not significantly reduced on day 14 after PPE instillation with pKGF-FLAG gene transfection compared to that of normal mice. These results indicated that KGF gene therapy with electroporation stimulated lung epithelial proliferation and protected depression of pulmonary function in a mouse emphysema model, suggesting a possible method of treating pulmonary emphysema. PMID:26160987
Linder, Cecilia Halling; Narisawa, Sonoko; Millán, José Luis; Magnusson, Per
2009-01-01
Three circulating human bone alkaline phosphatase (BALP) isoforms (B1, B2, and B/I) can be distinguished in healthy individuals and a fourth isoform (B1x) has been discovered in patients with chronic kidney disease and in bone tissue. The present study was designed to correlate differing glycosylation patterns of each BALP isoform with their catalytic activity towards presumptive physiological substrates and to compare those properties with two recombinant isoforms of the tissue-nonspecific ALP (TNALP) isozyme, i.e., TNALP-flag, used extensively for mutation analysis of hypophosphatasia mutations and sALP-FcD10, a chimeric enzyme recently used as therapeutic drug in a mouse model of infantile hypophosphatasia. The BALP isoforms were prepared from human osteosarcoma (SaOS-2) cells and the kinetic properties were evaluated using the synthetic substrate p-nitrophenylphosphate (pNPP) at pH 7.4 and 9.8, and the three suggested endogenous physiological substrates, i.e., inorganic pyrophosphate (PPi), pyridoxal 5′-phosphate (PLP), and phosphoethanolamine (PEA) at pH 7.4. Qualitative glycosylation differences were also assessed by lectin binding and precipitation. The kcat/KM was higher for B2 for all the investigated substrates. The catalytic activity towards PEA was essentially undetectable. The kinetic activity for TNALP-flag and sALP-FcD10 was similar to the activity of the human BALP isoforms. The BALP isoforms differed in their lectin-binding properties and dose-dependent lectin precipitation, which also demonstrated differences between native and denatured BALP isoforms. The observed differences in lectin specificity were attributed to N-linked carbohydrates. In conclusion, we demonstrate significantly different catalytic properties among the BALP isoforms due to structural differences in posttranslational glycosylation. Our data also suggests that PEA is not an endogenous substrate for the BALP isoforms or for the recombinant TNALP isoforms. The TNALP-flag and the sALP-FcD10 isoforms faithfully mimic the biological properties of the human BALP isoforms in vivo validating the use of these recombinant enzymes in studies aimed at dissecting the pathophysiology and treating hypophosphatasia. PMID:19631305
Halling Linder, Cecilia; Narisawa, Sonoko; Millán, José Luis; Magnusson, Per
2009-11-01
Three circulating human bone alkaline phosphatase (BALP) isoforms (B1, B2, and B/I) can be distinguished in healthy individuals and a fourth isoform (B1x) has been discovered in patients with chronic kidney disease and in bone tissue. The present study was designed to correlate differing glycosylation patterns of each BALP isoform with their catalytic activity towards presumptive physiological substrates and to compare those properties with two recombinant isoforms of the tissue-nonspecific ALP (TNALP) isozyme, i.e., TNALP-flag, used extensively for mutation analysis of hypophosphatasia mutations and sALP-FcD(10), a chimeric enzyme recently used as therapeutic drug in a mouse model of infantile hypophosphatasia. The BALP isoforms were prepared from human osteosarcoma (SaOS-2) cells and the kinetic properties were evaluated using the synthetic substrate p-nitrophenylphosphate (pNPP) at pH 7.4 and 9.8, and the three suggested endogenous physiological substrates, i.e., inorganic pyrophosphate (PP(i)), pyridoxal 5'-phosphate (PLP), and phosphoethanolamine (PEA) at pH 7.4. Qualitative glycosylation differences were also assessed by lectin binding and precipitation. The k(cat)/K(M) was higher for B2 for all the investigated substrates. The catalytic activity towards PEA was essentially undetectable. The kinetic activity for TNALP-flag and sALP-FcD(10) was similar to the activity of the human BALP isoforms. The BALP isoforms differed in their lectin binding properties and dose-dependent lectin precipitation, which also demonstrated differences between native and denatured BALP isoforms. The observed differences in lectin specificity were attributed to N-linked carbohydrates. In conclusion, we demonstrate significantly different catalytic properties among the BALP isoforms due to structural differences in posttranslational glycosylation. Our data also suggests that PEA is not an endogenous substrate for the BALP isoforms or for the recombinant TNALP isoforms. The TNALP-flag and the sALP-FcD(10) isoforms faithfully mimic the biological properties of the human BALP isoforms in vivo validating the use of these recombinant enzymes in studies aimed at dissecting the pathophysiology and treating hypophosphatasia.
No Experience Necessary: A Guide to Employment for the Female Liberal Arts Graduate.
ERIC Educational Resources Information Center
Friedman, Sande; Schwartz, Lois C.
A guide for beginning employment for female liberal arts graduates (referred to as FLAGs), this book describes 14 fields found to be presently most accessible to FLAGs without advanced degrees: advertising, the art world, banking and finance, book publishing, computer programing, fashion (and beauty), films, Government, magazine and newspaper…
NASA Astrophysics Data System (ADS)
Pingel, Nickolas; Pisano, D. J.
2018-01-01
Phased Array Feeds (PAFs) represent the next revolution in radio astronomy instrumentation. I will present results from the latest commissioning run from the Focal L-Band Array for the Green Bank telescope (FLAG), which holds the current world record for PAF sensitivity. Since we are able to operate at system temperatures comparable with the traditional GBT single pixel L-Band feed, the increase in the field-of-view provided by the beamforming capabilities of PAFs results in a dramatic (a factor of 5) increase in survey speeds. In particular, FLAG can probe similar neutral hydrogen column density regimes over a 4 sq. deg region in 24.6 minutes as opposed to 4.1 hours in an equivalent single pixel map (excluding observing overhead). In addition to comparisons between data taken with FLAG and the single-pixel L-Band feed, I will also discuss the technical aspects of the observing procedure, data reduction, and the transition path for FLAG from an instrument that is principle-investigator run to one that is general use. These FLAG results provide a very encouraging outlook on how the GBT will continue to compete with current and planned radio telescope facilities.
"Disappearance" and Feminist Research in the South African Academy of Humanities
ERIC Educational Resources Information Center
Bennett, Jane
2016-01-01
Following a global trend in humanities since the mid-1970s, South African humanities faculties began to include formal programmes in gender and sexualities studies from the mid-1990s on. While the immediate post-flag democratic era encouraged intellectual concentration on diverse questions of power and knowledge, the new century saw a decline in…
An Examination of Two Procedures for Identifying Consequential Item Parameter Drift
ERIC Educational Resources Information Center
Wells, Craig S.; Hambleton, Ronald K.; Kirkpatrick, Robert; Meng, Yu
2014-01-01
The purpose of the present study was to develop and evaluate two procedures flagging consequential item parameter drift (IPD) in an operational testing program. The first procedure was based on flagging items that exhibit a meaningful magnitude of IPD using a critical value that was defined to represent barely tolerable IPD. The second procedure…
Constructing and Validating the Foreign Language Attitudes and Goals Survey (FLAGS)
ERIC Educational Resources Information Center
Cid, Eva; Granena, Gisela; Tragant, Elsa
2009-01-01
The present study describes the process that was followed in the construction and validation of the foreign language attitudes and goals survey (FLAGS), a new questionnaire based on qualitative data from Tragant and Munoz [Tragant, Munoz, C., 2000. "La motivacion y su relacion con la edad en un contexto escolar de aprendizaje de una lengua…
10 CFR 1002.21 - Description of distinguishing flag.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false Description of distinguishing flag. 1002.21 Section 1002.21 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG Distinguishing Flag § 1002.21 Description of distinguishing flag. (a) The base or field of the flag shall be...
10 CFR 1002.22 - Use of distinguishing flag.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false Use of distinguishing flag. 1002.22 Section 1002.22 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG Distinguishing Flag § 1002.22 Use of distinguishing flag. (a) DOE distinguishing flags may be used only: (1) In the offices of the...
Barbour, Matthew A; Clark, Rulon W
2012-09-22
Many species approach, inspect and signal towards their predators. These behaviours are often interpreted as predator-deterrent signals--honest signals that indicate to a predator that continued hunting is likely to be futile. However, many of these putative predator-deterrent signals are given when no predator is present, and it remains unclear if and why such signals deter predators. We examined the effects of one such signal, the tail-flag display of California ground squirrels, which is frequently given both during and outside direct encounters with northern Pacific rattlesnakes. We video-recorded and quantified the ambush foraging responses of rattlesnakes to tail-flagging displays from ground squirrels. We found that tail-flagging deterred snakes from striking squirrels, most likely by advertising squirrel vigilance (i.e. readiness to dodge a snake strike). We also found that tail-flagging by adult squirrels increased the likelihood that snakes would leave their ambush site, apparently by elevating the vigilance of nearby squirrels which reduces the profitability of the ambush site. Our results provide some of the first empirical evidence of the mechanisms by which a prey display, although frequently given in the absence of a predator, may still deter predators during encounters.
Cloud based, Open Source Software Application for Mitigating Herbicide Drift
NASA Astrophysics Data System (ADS)
Saraswat, D.; Scott, B.
2014-12-01
The spread of herbicide resistant weeds has resulted in the need for clearly marked fields. In response to this need, the University of Arkansas Cooperative Extension Service launched a program named Flag the Technology in 2011. This program uses color-coded flags as a visual alert of the herbicide trait technology within a farm field. The flag based program also serves to help avoid herbicide misapplication and prevent herbicide drift damage between fields with differing crop technologies. This program has been endorsed by Southern Weed Science Society of America and is attracting interest from across the USA, Canada, and Australia. However, flags have risk of misplacement or disappearance due to mischief or severe windstorms/thunderstorms, respectively. This presentation will discuss the design and development of a cloud-based, free application utilizing open-source technologies, called Flag the Technology Cloud (FTTCloud), for allowing agricultural stakeholders to color code their farm fields for indicating herbicide resistant technologies. The developed software utilizes modern web development practices, widely used design technologies, and basic geographic information system (GIS) based interactive interfaces for representing, color-coding, searching, and visualizing fields. This program has also been made compatible for a wider usability on different size devices- smartphones, tablets, desktops and laptops.
Immunofluorescence Analysis of Endogenous and Exogenous Centromere-kinetochore Proteins
Niikura, Yohei; Kitagawa, Katsumi
2016-01-01
"Centromeres" and "kinetochores" refer to the site where chromosomes associate with the spindle during cell division. Direct visualization of centromere-kinetochore proteins during the cell cycle remains a fundamental tool in investigating the mechanism(s) of these proteins. Advanced imaging methods in fluorescence microscopy provide remarkable resolution of centromere-kinetochore components and allow direct observation of specific molecular components of the centromeres and kinetochores. In addition, methods of indirect immunofluorescent (IIF) staining using specific antibodies are crucial to these observations. However, despite numerous reports about IIF protocols, few discussed in detail problems of specific centromere-kinetochore proteins.1-4 Here we report optimized protocols to stain endogenous centromere-kinetochore proteins in human cells by using paraformaldehyde fixation and IIF staining. Furthermore, we report protocols to detect Flag-tagged exogenous CENP-A proteins in human cells subjected to acetone or methanol fixation. These methods are useful in detecting and quantifying endogenous centromere-kinetochore proteins and Flag-tagged CENP-A proteins, including those in human cells. PMID:26967065
Algorithms on Flag Manifolds for Knowledge Discovery in N-way Arrays
2015-11-20
that three of 18 subjects will become symptomatic after only 8 hours. Host pathway analysis of a human endotoxin gene expression data set revealed a 14...pathway analysis of a human endotoxin gene expression data set revealed a 14 pathway signature that identified symptomatic subjects within 2-3 hours post
China Report, Red Flag, Number 8, 16 April 1986.
1986-06-02
principles of Marxism and to the destiny of our socialist litera- ture and art. Over the past few years, Comrade Liu Zaifu has published a series of theses...teristics of this figure are the ideological embryo of the modern theory of human nature and humanism, and the contradiction between his democratic
Red eyes and red-flags: improving ophthalmic assessment and referral in primary care.
Kilduff, Caroline; Lois, Charis
2016-01-01
Up to five percent of primary care consultations are eye-related, yet 96% of General Practitioners (GPs) do not undergo postgraduate ophthalmology training. Most do not feel assured performing eye assessments. Some red eye conditions can become sight threatening, and often exhibit red-flag features. These features include moderate pain, photophobia, reduced visual acuity (VA), eye-trauma, or unilateral marked redness. The aim of this project was to improve primary care assessment and referral of patients presenting with red-flag features based on the NICE 'Red Eye' Clinical Knowledge Summary recommendations. Data was collected retrospectively from 139 red eye consultations. A practice meeting highlighted poor awareness of red-flag features, low confidence levels in eye assessments, and time-constraints during appointments. Interventions were based on feedback from staff. These included a primary care teaching session on red-flag features, a VA measurement tutorial, and provision of a red eye toolkit, including VA equipment, to each consultation room. At baseline, each patient had on average 0.9 red-flag features assessed. Only 36.0% (9/25) of patients with red-flag features were appropriately referred to same-day ophthalmology services. Following two improvement cycles, a significant improvement was seen in almost every parameter. On average, each patient had 2.7 red-flag features assessed (vs 0.9, p<0.001). VA was assessed in 55.6% of consultations (vs 7.9%, p<0.001), pain was quantified in 81.5% (vs 20.9%, p=0.005), eye-trauma or foreign-body (51.8% vs 8.6%, p<0.001), extent of redness was documented in 66.7% (vs 14.4%, p<0.001). Only photophobia remained poorly assessed (18.5% vs 14.4%, p=0.75). Following this, 75.0% (6/8) of patients were appropriately referred. This project reflected the literature regarding low confidence and inexperience amongst GPs when faced with ophthalmic conditions. Improvements in education are required to ensure accurate assessments can be undertaken in a time-constrained environment.
2008-06-17
CAPE CANAVERAL, Fla. – On Launch Pad 39A at NASA's Kennedy Space Center, Daytona International Speedway President Robin Braig (left) and 2008 Daytona 500 winner Ryan Newman pose for photographers with the Daytona International Speedway show car. Newman is visiting Kennedy in honor of NASA's 50th anniversary and the 50th running of NASCAR's Daytona 500 in February. NASA presented Newman two green racing flags that were flown last February aboard space shuttle Atlantis' STS-122 mission to the International Space Station. One flag was given to Newman, the second was presented to Daytona 500 Experience General Manager Kim Isemann. A third flag that was flown will be kept by NASA for public display. The connection between NASA and Daytona's International Speedway extends beyond their close proximity to one another. During recent years, technology developed for the space program has found many uses on Earth, including helping NASCAR drivers stay safe and increase performance. Photo credit: NASA/Kim Shiflett
Mandating responsible flagging practices as a strategy for reducing the risk of coastal oil spills.
Miller, Dana D; Hotte, Ngaio; Sumaila, U Rashid
2014-04-15
As human civilization is becoming more aware of the negative impact our actions can inflict upon the natural world, the intensification of fossil fuel extraction and industrial development is being met with increasing opposition. In Western Canada, proposals that would increase the volume of petroleum transported by pipelines and by tankers through the coastal waters of British Columbia have engaged the province in debate. To ease public concern on the risk of a coastal oil spill, there are additional commitments that involved parties could make. There is evidence to show that the practice of registering vessels under foreign flags of states that have exhibited failure in compliance with international obligations is more common amongst petroleum tankers that have been involved in large-scale oil spills. To prove that they are committed to reducing the risk of oil spills, businesses need to stop registering their vessels under flags of foreign, non-compliant states. Copyright © 2014 Elsevier Ltd. All rights reserved.
Rolling Band Artifact Flagging in the Kepler Data Pipeline
NASA Astrophysics Data System (ADS)
Clarke, Bruce; Kolodziejczak, Jeffery J; Caldwell, Douglas A.
2014-06-01
Instrument-induced artifacts in the raw Kepler pixel data include time-varying crosstalk from the fine guidance sensor (FGS) clock signals, manifestations of drifting moiré pattern as locally correlated nonstationary noise and rolling bands in the images. These systematics find their way into the calibrated pixel time series and ultimately into the target flux time series. The Kepler pipeline module Dynablack models the FGS crosstalk artifacts using a combination of raw science pixel data, full frame images, reverse-clocked pixel data and ancillary temperature data. The calibration module (CAL) uses the fitted Dynablack models to remove FGS crosstalk artifacts in the calibrated pixels by adjusting the black level correction per cadence. Dynablack also detects and flags spatial regions and time intervals of strong time-varying black-level. These rolling band artifact (RBA) flags are produced on a per row per cadence basis by searching for transit signatures in the Dynablack fit residuals. The Photometric Analysis module (PA) generates per target per cadence data quality flags based on the Dynablack RBA flags. Proposed future work includes using the target data quality flags as a basis for de-weighting in the Presearch Data Conditioning (PDC), Transiting Planet Search (TPS) and Data Validation (DV) pipeline modules. We discuss the effectiveness of RBA flagging for downstream users and illustrate with some affected light curves. We also discuss the implementation of Dynablack in the Kepler data pipeline and present results regarding the improvement in calibrated pixels and the expected improvement in cotrending performance as a result of including FGS corrections in the calibration. Funding for the Kepler Mission has been provided by the NASA Science Mission Directorate.
Consumer preferences for front-of-pack calories labelling.
van Kleef, Ellen; van Trijp, Hans; Paeps, Frederic; Fernández-Celemín, Laura
2008-02-01
In light of the emerging obesity pandemic, front-of-pack calories labels may be an important tool to assist consumers in making informed healthier food choices. However, there is little prior research to guide key decisions on whether caloric content should be expressed in absolute terms or relative to recommended daily intake, whether it should be expressed in per serving or per 100 g and whether the information should be further brought alive for consumers in terms of what the extra calorie intake implies in relation to activity levels. The present study aimed at providing more insight into consumers' appreciation of front-of-pack labelling of caloric content of food products and their specific preferences for alternative execution formats for such information in Europe. For this purpose, eight executions of front-of-pack calorie flags were designed and their appeal and information value were extensively discussed with consumers through qualitative research in four different countries (Germany, The Netherlands, France and the UK). The results show that calories are well-understood and that participants were generally positive about front-of-pack flags, particularly when flags are uniform across products. The most liked flags are the simpler flags depicting only the number of calories per serving or per 100 g, while more complex flags including references to daily needs or exercise and the flag including a phrase referring to balanced lifestyle were least preferred. Some relevant differences between countries were observed. Although participants seem to be familiar with the notion of calories, they do not seem to fully understand how to apply them. From the results, managerial implications for the design and implementation of front-of-pack calorie labelling as well as important directions for future research are discussed.
Consumer preferences for front-of-pack calories labelling
van Kleef, Ellen; van Trijp, Hans; Paeps, Frederic; Fernández-Celemín, Laura
2008-01-01
Objective In light of the emerging obesity pandemic, front-of-pack calories labels may be an important tool to assist consumers in making informed healthier food choices. However, there is little prior research to guide key decisions on whether caloric content should be expressed in absolute terms or relative to recommended daily intake, whether it should be expressed in per serving or per 100 g and whether the information should be further brought alive for consumers in terms of what the extra calorie intake implies in relation to activity levels. The present study aimed at providing more insight into consumers’ appreciation of front-of-pack labelling of caloric content of food products and their specific preferences for alternative execution formats for such information in Europe. Design For this purpose, eight executions of front-of-pack calorie flags were designed and their appeal and information value were extensively discussed with consumers through qualitative research in four different countries (Germany, The Netherlands, France and the UK). Results The results show that calories are well-understood and that participants were generally positive about front-of-pack flags, particularly when flags are uniform across products. The most liked flags are the simpler flags depicting only the number of calories per serving or per 100 g, while more complex flags including references to daily needs or exercise and the flag including a phrase referring to balanced lifestyle were least preferred. Some relevant differences between countries were observed. Although participants seem to be familiar with the notion of calories, they do not seem to fully understand how to apply them. Conclusion From the results, managerial implications for the design and implementation of front-of-pack calorie labelling as well as important directions for future research are discussed. PMID:17601362
Kock, Alison; Waries, Sarah; O’Riain, M. Justin
2017-01-01
White sharks (Carcharodon carcharias) are apex predators that play an important role in the structure and stability of marine ecosystems. Despite their ecological importance and protected status, white sharks are still subject to lethal control to reduce the risk of shark bites for recreational water users. The Shark Spotters program, pioneered in Cape Town, South Africa, provides a non-lethal alternative for reducing the risk of human-shark conflict. In this study we assessed the efficacy of the Shark Spotters program in reducing overlap between water users and white sharks at two popular beaches in False Bay, South Africa. We investigated seasonal and diel patterns in water use and shark presence at each beach, and thereafter quantified the impact of different shark warnings from shark spotters on water user abundance. We also assessed the impact of a fatal shark incident on patterns of water use. Our results revealed striking diel and seasonal overlap between white sharks and water users at both beaches. Despite this, there was a low rate of shark-human incidents (0.5/annum) which we attribute partly to the success of the Shark Spotters program. Shark spotters use visual (coloured flags) and auditory (siren) cues to inform water users of risk associated with white shark presence in the surf zone. Our results showed that the highest risk category (denoted by a white flag and accompanying siren) caused a significant reduction in water user abundance; however the secondary risk category (denoted by a red flag with no siren) had no significant effect on water users. A fatal shark incident was shown to negatively impact the number of water users present for at least three months following the incident. Our results indicate that the Shark Spotters program effectively reduces spatial overlap between white sharks and water users when the risk of conflict is highest. PMID:28945806
Engelbrecht, Tamlyn; Kock, Alison; Waries, Sarah; O'Riain, M Justin
2017-01-01
White sharks (Carcharodon carcharias) are apex predators that play an important role in the structure and stability of marine ecosystems. Despite their ecological importance and protected status, white sharks are still subject to lethal control to reduce the risk of shark bites for recreational water users. The Shark Spotters program, pioneered in Cape Town, South Africa, provides a non-lethal alternative for reducing the risk of human-shark conflict. In this study we assessed the efficacy of the Shark Spotters program in reducing overlap between water users and white sharks at two popular beaches in False Bay, South Africa. We investigated seasonal and diel patterns in water use and shark presence at each beach, and thereafter quantified the impact of different shark warnings from shark spotters on water user abundance. We also assessed the impact of a fatal shark incident on patterns of water use. Our results revealed striking diel and seasonal overlap between white sharks and water users at both beaches. Despite this, there was a low rate of shark-human incidents (0.5/annum) which we attribute partly to the success of the Shark Spotters program. Shark spotters use visual (coloured flags) and auditory (siren) cues to inform water users of risk associated with white shark presence in the surf zone. Our results showed that the highest risk category (denoted by a white flag and accompanying siren) caused a significant reduction in water user abundance; however the secondary risk category (denoted by a red flag with no siren) had no significant effect on water users. A fatal shark incident was shown to negatively impact the number of water users present for at least three months following the incident. Our results indicate that the Shark Spotters program effectively reduces spatial overlap between white sharks and water users when the risk of conflict is highest.
10 CFR 1002.31 - Unauthorized uses of the seal and flag.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false Unauthorized uses of the seal and flag. 1002.31 Section 1002.31 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG Unauthorized Uses § 1002.31 Unauthorized uses of the seal and flag. The official seal and distinguishing flag...
10 CFR 1002.31 - Unauthorized uses of the seal and flag.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 4 2011-01-01 2011-01-01 false Unauthorized uses of the seal and flag. 1002.31 Section 1002.31 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG Unauthorized Uses § 1002.31 Unauthorized uses of the seal and flag. The official seal and distinguishing flag...
49 CFR 393.87 - Warning flags on projecting loads.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 5 2012-10-01 2012-10-01 false Warning flags on projecting loads. 393.87 Section... ACCESSORIES NECESSARY FOR SAFE OPERATION Miscellaneous Parts and Accessories § 393.87 Warning flags on... load marked with red or orange fluorescent warning flags. Each warning flag must be at least 457 mm (18...
49 CFR 393.87 - Warning flags on projecting loads.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 5 2011-10-01 2011-10-01 false Warning flags on projecting loads. 393.87 Section... ACCESSORIES NECESSARY FOR SAFE OPERATION Miscellaneous Parts and Accessories § 393.87 Warning flags on... load marked with red or orange fluorescent warning flags. Each warning flag must be at least 457 mm (18...
49 CFR 393.87 - Warning flags on projecting loads.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 49 Transportation 5 2013-10-01 2013-10-01 false Warning flags on projecting loads. 393.87 Section... ACCESSORIES NECESSARY FOR SAFE OPERATION Miscellaneous Parts and Accessories § 393.87 Warning flags on... load marked with red or orange fluorescent warning flags. Each warning flag must be at least 457 mm (18...
49 CFR 393.87 - Warning flags on projecting loads.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 5 2010-10-01 2010-10-01 false Warning flags on projecting loads. 393.87 Section... ACCESSORIES NECESSARY FOR SAFE OPERATION Miscellaneous Parts and Accessories § 393.87 Warning flags on... load marked with red or orange fluorescent warning flags. Each warning flag must be at least 457 mm (18...
49 CFR 393.87 - Warning flags on projecting loads.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 49 Transportation 5 2014-10-01 2014-10-01 false Warning flags on projecting loads. 393.87 Section... ACCESSORIES NECESSARY FOR SAFE OPERATION Miscellaneous Parts and Accessories § 393.87 Warning flags on... load marked with red or orange fluorescent warning flags. Each warning flag must be at least 457 mm (18...
46 CFR 282.11 - Ranking of flags.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 8 2010-10-01 2010-10-01 false Ranking of flags. 282.11 Section 282.11 Shipping... COMMERCE OF THE UNITED STATES Foreign-Flag Competition § 282.11 Ranking of flags. The operators under each... priority of costs which are representative of the flag. For liner cargo vessels, the ranking of operators...
Fouled Anchors: The CONSTELLATION Question Answered
1991-09-01
brought to Baltimore in 1955 and tuned over to the Constellation Commuttee of the Flag House Associat on for public display. In response to Howard...Josephus Daniels spoke before the House of Representatives Committee on Naval Affairs in 1914, supporting a bill to fund restoration, he presented a...where she was publicly exhibited as having been built in Baltimore in 1797. In 1928, the Star-Spangled Banner Flag House Association, incorporated in 1927
QTL mapping of flag leaf-related traits in wheat (Triticum aestivum L.).
Liu, Kaiye; Xu, Hao; Liu, Gang; Guan, Panfeng; Zhou, Xueyao; Peng, Huiru; Yao, Yingyin; Ni, Zhongfu; Sun, Qixin; Du, Jinkun
2018-04-01
QTL controlling flag leaf length, flag leaf width, flag leaf area and flag leaf angle were mapped in wheat. This study aimed to advance our understanding of the genetic mechanisms underlying morphological traits of the flag leaves of wheat (Triticum aestivum L.). A recombinant inbred line (RIL) population derived from ND3331 and the Tibetan semi-wild wheat Zang1817 was used to identify quantitative trait loci (QTLs) controlling flag leaf length (FLL), flag leaf width (FLW), flag leaf area (FLA), and flag leaf angle (FLANG). Using an available simple sequence repeat genetic linkage map, 23 putative QTLs for FLL, FLW, FLA, and FLANG were detected on chromosomes 1B, 2B, 3A, 3D, 4B, 5A, 6B, 7B, and 7D. Individual QTL explained 4.3-68.52% of the phenotypic variance in different environments. Four QTLs for FLL, two for FLW, four for FLA, and five for FLANG were detected in at least two environments. Positive alleles of 17 QTLs for flag leaf-related traits originated from ND3331 and 6 originated from Zang1817. QTLs with pleiotropic effects or multiple linked QTL were also identified on chromosomes 1B, 4B, and 5A; these are potential target regions for fine-mapping and marker-assisted selection in wheat breeding programs.
Barbour, Matthew A.; Clark, Rulon W.
2012-01-01
Many species approach, inspect and signal towards their predators. These behaviours are often interpreted as predator-deterrent signals—honest signals that indicate to a predator that continued hunting is likely to be futile. However, many of these putative predator-deterrent signals are given when no predator is present, and it remains unclear if and why such signals deter predators. We examined the effects of one such signal, the tail-flag display of California ground squirrels, which is frequently given both during and outside direct encounters with northern Pacific rattlesnakes. We video-recorded and quantified the ambush foraging responses of rattlesnakes to tail-flagging displays from ground squirrels. We found that tail-flagging deterred snakes from striking squirrels, most likely by advertising squirrel vigilance (i.e. readiness to dodge a snake strike). We also found that tail-flagging by adult squirrels increased the likelihood that snakes would leave their ambush site, apparently by elevating the vigilance of nearby squirrels which reduces the profitability of the ambush site. Our results provide some of the first empirical evidence of the mechanisms by which a prey display, although frequently given in the absence of a predator, may still deter predators during encounters. PMID:22787023
Fuehrer, Hans-Peter; Igel, Petra; Treiber, Moritz; Baumann, Timo A; Riedl, Julia; Swoboda, Paul; Joachim, Anja; Noedl, Harald
2012-10-01
A large variety of ectoparasites parasitizing on livestock, dogs, and rodents are documented throughout the world, of which several are proven vectors for major (including zoonotic) diseases affecting humans and/or livestock. However, there remains a significant lack of knowledge in regard to the ectoparasite fauna in remote regions of the developing world, such as southeastern Bangladesh, and an urgent need to investigate this fauna to improve diagnostic options. In the course of the present study, more than 5,300 ectoparasites were collected by flag dragging and handpicking of livestock, dogs, and rodents in the District of Bandarban (Chittagong Hill Tracts) in southeastern Bangladesh. Three tick species were identified: Haemaphysalis bispinosa (flagging, cattle, goats, and dogs), Rhipicephalus microplus (cattle, goats), and Rhipicephalus sanguineus (dogs, goats, and flagging). H. bispinosa was the dominant tick species on mammalian hosts as well as on vegetation. Furthermore, Ctenocephalides canis (dogs, goats) and Linognatus sp. (goat) were found. Overall, 73 rodents of eight different species (e.g., Mus musculus, Rattus sikkimensis, Bandicota bengalensis, and Niviventer sp.) hosted a variety of ectoparasites such as mites (Laelaps nuttali, Laelaps echidninus, Lyponissoides sp. and Ornithonyssus bacoti), fleas (Xenopsylla cheopis), and one myiasis-causing dipteran species. Monitoring the ectoparasite burden of livestock and other mammals is urgently needed in order to control ectoparasites associated with social and economic burden (e.g., reduced milk production, weight loss). Several zoonotic diseases can be transmitted by ectoparasites in this area, where the majority of the population live in basic housing conditions and in direct contact with livestock, dogs, and rodents.
Rome III survey of irritable bowel syndrome among ethnic Malays
Lee, Yeong Yeh; Waid, Anuar; Tan, Huck Joo; Chua, Andrew Seng Boon; Whitehead, William E
2012-01-01
AIM: To survey irritable bowel syndrome (IBS) using Rome III criteria among Malays from the north-eastern region of Peninsular Malaysia. METHODS: A previously validated Malay language Rome III IBS diagnostic questionnaire was used in the current study. A prospective sample of 232 Malay subjects (80% power) was initially screened. Using a stratified random sampling strategy, a total of 221 Malay subjects (112 subjects in a “full time job” and 109 subjects in “no full time job”) were recruited. Subjects were visitors (friends and relatives) within the hospital compound and were representative of the local community. Red flags and psychosocial alarm symptoms were also assessed in the current study using previously translated and validated questionnaires. Subjects with IBS were sub-typed into constipation-predominant, diarrhea-predominant, mixed type and un-subtyped. Univariable and multivariable analyses were used to test for association between socioeconomic factors and presence of red flags and psychosocial alarm features among the Malays with IBS. RESULTS: IBS was present in 10.9% (24/221), red flags in 22.2% (49/221) and psychosocial alarm features in 9.0% (20/221). Red flags were more commonly reported in subjects with IBS (83.3%) than psychosocial alarm features (20.8%, P < 0.001). Subjects with IBS were older (mean age 41.4 years vs 36.9 years, P = 0.08), but no difference in gender was noted (P = 0.4). Using univariable analysis, IBS was significantly associated with a tertiary education, high individual income above RM1000, married status, ex-smoker and the presence of red flags (all P < 0.05). In multiple logistic regression analysis, only the presence of red flags was significantly associated with IBS (odds ratio: 0.02, 95%CI: 0.004-0.1, P < 0.001). The commonest IBS sub-type was mixed type (58.3%), followed by constipation-predominant (20.8%), diarrhea-predominant (16.7%) and un-subtyped (4.2%). Four of 13 Malay females (30.8%) with IBS also had menstrual pain. Most subjects with IBS had at least one red flag (70.8%), 12.5% had two red flags and 16.7% with no red flags. The commonest red flag was a bowel habit change in subjects > 50 years old and this was reported by 16.7% of subjects with IBS. CONCLUSION: Using the Rome III criteria, IBS was common among ethnic Malays from the north-eastern region of Peninsular Malaysia. PMID:23197894
Cystatin C–Adiponectin Complex in Plasma Associates with Coronary Plaque Instability
Matsuoka, Tetsuro; Kayama, Kento; Onishi, Sumire; Matsuo, Natsumi
2017-01-01
Aim: Adiponectin (APN) is an adipocyte-derived bioactive molecule with antiatherogenic properties. We previously reported that cystatin C (CysC) abolished the anti-atherogenic effects of APN. We aimed to elucidate the clinical significance of CysC–APN complex in patients with coronary artery disease (CAD). Methods: We enrolled 43 stable CAD male patients to examine the relationship between CysC–APN complex and coronary plaque characteristics. Serum was immunoprecipitated by the anti-APN antibody and immunoblotted by the anti-CysC antibody to demonstrate the presence of CysC–APN complexes in vivo. To confirm their binding in vitro, HEK293T cell lysates overexpressing myc-APN and FLAG-CysC were immunoprecipitated with an anti-myc or anti-FLAG antibody, followed by immunoblotting with an anti-APN or anti-CysC antibody. Results: CysC was identified as a specific co-immunoprecipitant with APN by the anti-APN antibody in human serum. In vitro, FLAG-CysC was co-immunoprecipitated with myc-APN by the antimyc antibody and myc-APN was co-immunoprecipitated with FLAG-CysC by the anti-FLAG antibody. Among CAD patients, serum CysC–APN complex levels negatively correlated with fibrotic components of coronary plaques and positively correlated with either necrotic or lipidic plus necrotic components. Plaque burden negatively correlated with serum APN levels but not serum CysC–APN complex levels. Serum CysC levels had no association with plaque characteristics. In multivariate analysis, CysC–APN complex levels were identified as the strongest negative factor for fibrotic components and the strongest positive factor for both necrotic and lipidic plus necrotic components. Conclusion: Measuring serum CysC–APN complex levels is helpful for evaluating coronary plaque instability in CAD patients. PMID:28321013
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-14
... the relevant flags, as described below, for orders that add liquidity to the EDGA book. Specifically... the following flags: Flag B for orders that add liquidity to the EDGA book in Tape B securities; Flag V for orders that add liquidity to the EDGA book in Tape A securities; Flag Y for orders that add...
FLIP for FLAG model visualization
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wooten, Hasani Omar
A graphical user interface has been developed for FLAG users. FLIP (FLAG Input deck Parser) provides users with an organized view of FLAG models and a means for efficiently and easily navigating and editing nodes, parameters, and variables.
Where no flag has gone before: Political and technical aspects of placing a flag on the Moon
NASA Technical Reports Server (NTRS)
Platoff, Anne M.
1993-01-01
The flag on the Moon represents an important event in vexillological history. The political and technical aspects of placing a flag on the Moon, focusing on the first Moon landing, is examined. During their historic extravehicular activity, the Apollo 11 crew planted the flag of the United States on the lunar surface. This flag-raising was strictly a symbolic activity, as the United Nations Treaty on Outer Space precluded any territorial claim. Nevertheless, there were domestic and international debates over the appropriateness of the event. Congress amended the agency's appropriations bill to prevent the National Aeronautics and Space Administration (NASA) from placing flags of other nations, or those of international associations, on the Moon during missions funded solely by the United States. Like any activity in space exploration, the Apollo flag-raising also provided NASA engineers with an interesting technical challenge. They designed a flagpole with a horizontal bar allowing the flag to 'fly' without the benefit of wind to overcome the effects of the Moon's lack of an atmosphere. Other factors considered in the design were weight, heat resistance, and ease of assembly by astronauts whose space suits restricted their range of movement and ability to grasp items. As NASA plans a return to the Moon and an expedition to Mars, we will likely see flags continue to go 'where no flag has gone before'.
Experimental investigation of flow field around the elastic flag flapping in periodic state
NASA Astrophysics Data System (ADS)
Jia, Yongxia; Jia, Lichao; Su, Zhuang; Yuan, Huijing
2018-05-01
The flapping of a flag in the wind is a classical fluid-structure problem that concerns the interaction of elastic bodies with ambient fluid. We focus on the desirable experimental results of the flow around the flapping flag. By immersing the elastic yet self-supporting heavy flag into water flow, we use particle image velocimetry (PIV) techniques to obtain the whole flow field around the midspan of the flag interacting with a fluid in periodic state. A unique PIV image processing method is used to measure near-wall flow velocities around a moving elastic flag. There exists a thin flow circulation region on the suction side of the flag in periodic state. This observation suggests that viscous flow models may be needed to improve the theoretical predictions of the flapping flag in periodic state, especially in a large amplitude.
Red eyes and red-flags: improving ophthalmic assessment and referral in primary care
Kilduff, Caroline; Lois, Charis
2016-01-01
Up to five percent of primary care consultations are eye-related, yet 96% of General Practitioners (GPs) do not undergo postgraduate ophthalmology training. Most do not feel assured performing eye assessments. Some red eye conditions can become sight threatening, and often exhibit red-flag features. These features include moderate pain, photophobia, reduced visual acuity (VA), eye-trauma, or unilateral marked redness. The aim of this project was to improve primary care assessment and referral of patients presenting with red-flag features based on the NICE ‘Red Eye’ Clinical Knowledge Summary recommendations. Data was collected retrospectively from 139 red eye consultations. A practice meeting highlighted poor awareness of red-flag features, low confidence levels in eye assessments, and time-constraints during appointments. Interventions were based on feedback from staff. These included a primary care teaching session on red-flag features, a VA measurement tutorial, and provision of a red eye toolkit, including VA equipment, to each consultation room. At baseline, each patient had on average 0.9 red-flag features assessed. Only 36.0% (9/25) of patients with red-flag features were appropriately referred to same-day ophthalmology services. Following two improvement cycles, a significant improvement was seen in almost every parameter. On average, each patient had 2.7 red-flag features assessed (vs 0.9, p<0.001). VA was assessed in 55.6% of consultations (vs 7.9%, p<0.001), pain was quantified in 81.5% (vs 20.9%, p=0.005), eye-trauma or foreign-body (51.8% vs 8.6%, p<0.001), extent of redness was documented in 66.7% (vs 14.4%, p<0.001). Only photophobia remained poorly assessed (18.5% vs 14.4%, p=0.75). Following this, 75.0% (6/8) of patients were appropriately referred. This project reflected the literature regarding low confidence and inexperience amongst GPs when faced with ophthalmic conditions. Improvements in education are required to ensure accurate assessments can be undertaken in a time-constrained environment. PMID:27493748
Code of Federal Regulations, 2012 CFR
2012-01-01
... × 4 feet; (2) The Administrator's Flag has four stars; (3) The Deputy Administrator's Flag has three stars; and (4) The Associate Deputy Administrator's Flag has two stars. (b) Flags representing these...
Code of Federal Regulations, 2014 CFR
2014-01-01
... × 4 feet; (2) The Administrator's Flag has four stars; (3) The Deputy Administrator's Flag has three stars; and (4) The Associate Deputy Administrator's Flag has two stars. (b) Flags representing these...
Code of Federal Regulations, 2010 CFR
2010-01-01
... × 4 feet; (2) The Administrator's Flag has four stars; (3) The Deputy Administrator's Flag has three stars; and (4) The Associate Deputy Administrator's Flag has two stars. (b) Flags representing these...
Code of Federal Regulations, 2013 CFR
2013-01-01
... × 4 feet; (2) The Administrator's Flag has four stars; (3) The Deputy Administrator's Flag has three stars; and (4) The Associate Deputy Administrator's Flag has two stars. (b) Flags representing these...
Code of Federal Regulations, 2011 CFR
2011-01-01
... × 4 feet; (2) The Administrator's Flag has four stars; (3) The Deputy Administrator's Flag has three stars; and (4) The Associate Deputy Administrator's Flag has two stars. (b) Flags representing these...
Navigating a ship with a broken compass: evaluating standard algorithms to measure patient safety.
Hefner, Jennifer L; Huerta, Timothy R; McAlearney, Ann Scheck; Barash, Barbara; Latimer, Tina; Moffatt-Bruce, Susan D
2017-03-01
Agency for Healthcare Research and Quality (AHRQ) software applies standardized algorithms to hospital administrative data to identify patient safety indicators (PSIs). The objective of this study was to assess the validity of PSI flags and report reasons for invalid flagging. At a 6-hospital academic medical center, a retrospective analysis was conducted of all PSIs flagged in fiscal year 2014. A multidisciplinary PSI Quality Team reviewed each flagged PSI based on quarterly reports. The positive predictive value (PPV, the percent of clinically validated cases) was calculated for 12 PSI categories. The documentation for each reversed case was reviewed to determine the reasons for PSI reversal. Of 657 PSI flags, 185 were reversed. Seven PSI categories had a PPV below 75%. Four broad categories of reasons for reversal were AHRQ algorithm limitations (38%), coding misinterpretations (45%), present upon admission (10%), and documentation insufficiency (7%). AHRQ algorithm limitations included 2 subcategories: an "incident" was inherent to the procedure, or highly likely (eg, vascular tumor bleed), or an "incident" was nonsignificant, easily controlled, and/or no intervention was needed. These findings support previous research highlighting administrative data problems. Additionally, AHRQ algorithm limitations was an emergent category not considered in previous research. Herein we present potential solutions to address these issues. If, despite poor validity, US policy continues to rely on PSIs for incentive and penalty programs, improvements are needed in the quality of administrative data and the standardized PSI algorithms. These solutions require national motivation, research attention, and dissemination support. © The Author 2016. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com
President Nixon and Apollo 13 crewmen at Hickam AFB
1970-04-18
S70-15526 (18 April 1970) --- President Richard M. Nixon and the Apollo 13 crew members pay honor to the United States flag during the post-mission ceremonies at Hickam Air Force Base, Hawaii. Astronauts James A. Lovell Jr., (United States Navy Captain, salutes the flag) commander; John L. Swigert Jr., command module pilot (right); and Fred W. Haise Jr., lunar module pilot (left), were presented the Presidential Medal of Freedom by the Chief Executive. The Apollo 13 splashdown occurred at 12:07:44 p.m. (CST), April 17, 1970, about a day and a half prior to the award presentation.
Current markers of the Athlete Blood Passport do not flag microdose EPO doping.
Ashenden, Michael; Gough, Clare E; Garnham, Andrew; Gore, Christopher J; Sharpe, Ken
2011-09-01
The Athlete Blood Passport is the most recent tool adopted by anti-doping authorities to detect athletes using performance-enhancing drugs such as recombinant human erythropoietin (rhEPO). This strategy relies on detecting abnormal variations in haematological variables caused by doping, against a background of biological and analytical variability. Ten subjects were given twice weekly intravenous injections of rhEPO for up to 12 weeks. Full blood counts were measured using a Sysmex XE-2100 automated haematology analyser, and total haemoglobin mass via a carbon monoxide rebreathing test. The sensitivity of the passport to flag abnormal deviations in blood values was evaluated using dedicated Athlete Blood Passport software. Our treatment regimen elicited a 10% increase in total haemoglobin mass equivalent to approximately two bags of reinfused blood. The passport software did not flag any subjects as being suspicious of doping whilst they were receiving rhEPO. We conclude that it is possible for athletes to use rhEPO without eliciting abnormal changes in the blood variables currently monitored by the Athlete Blood Passport.
1969-07-20
The first manned lunar landing mission, Apollo 11, launched from the Kennedy Space Flight Center (KSC) in Florida via the Marshall Space Flight Center (MSFC) developed Saturn V launch vehicle on July 16, 1969 and safely returned to Earth on July 24, 1969. Astronauts onboard included Neil A. Armstrong, commander; Michael Collins, Command Module (CM) pilot; and Edwin E. Aldrin, Jr., Lunar Module (LM) pilot. The CM, “Columbia”, piloted by Collins, remained in a parking orbit around the Moon while the LM, “Eagle'', carrying astronauts Armstrong and Aldrin, landed on the Moon in the Sea of Tranquility. On July 20, 1969, Armstrong was the first human to ever stand on the lunar surface, followed by Aldrin. During 2½ hours of surface exploration, the crew set up experiments, collected 47 pounds of lunar surface material for analysis back on Earth, planted the U.S Flag, and left a message for all mankind. In this photograph, Armstrong is removing scientific equipment from a storage bay of the LM. The brilliant sunlight emphasizes the U. S. Flag to the left. The object near the flag is the Solar Wind Composition Experiment deployed by Aldrin earlier.
Code of Federal Regulations, 2010 CFR
2010-10-01
... devices for daytime flagging include “ STOP/SLOW” paddles or red flags. For nighttime flagging, a... Administration's Manual on Uniform Traffic Control Devices addresses standards and guides for flaggers and... follow them to the greatest extent possible. Copies of the latest MUTCD provisions regarding flagging...
Sunglint Detection for Unmanned and Automated Platforms
Garaba, Shungudzemwoyo Pascal; Schulz, Jan; Wernand, Marcel Robert; Zielinski, Oliver
2012-01-01
We present an empirical quality control protocol for above-water radiometric sampling focussing on identifying sunglint situations. Using hyperspectral radiometers, measurements were taken on an automated and unmanned seaborne platform in northwest European shelf seas. In parallel, a camera system was used to capture sea surface and sky images of the investigated points. The quality control consists of meteorological flags, to mask dusk, dawn, precipitation and low light conditions, utilizing incoming solar irradiance (ES) spectra. Using 629 from a total of 3,121 spectral measurements that passed the test conditions of the meteorological flagging, a new sunglint flag was developed. To predict sunglint conspicuous in the simultaneously available sea surface images a sunglint image detection algorithm was developed and implemented. Applying this algorithm, two sets of data, one with (having too much or detectable white pixels or sunglint) and one without sunglint (having least visible/detectable white pixel or sunglint), were derived. To identify the most effective sunglint flagging criteria we evaluated the spectral characteristics of these two data sets using water leaving radiance (LW) and remote sensing reflectance (RRS). Spectral conditions satisfying ‘mean LW (700–950 nm) < 2 mW·m−2·nm−1·Sr−1’ or alternatively ‘minimum RRS (700–950 nm) < 0.010 Sr−1’, mask most measurements affected by sunglint, providing an efficient empirical flagging of sunglint in automated quality control.
Dynamic Black-Level Correction and Artifact Flagging in the Kepler Data Pipeline
NASA Technical Reports Server (NTRS)
Clarke, B. D.; Kolodziejczak, J. J.; Caldwell, D. A.
2013-01-01
Instrument-induced artifacts in the raw Kepler pixel data include time-varying crosstalk from the fine guidance sensor (FGS) clock signals, manifestations of drifting moiré pattern as locally correlated nonstationary noise and rolling bands in the images which find their way into the calibrated pixel time series and ultimately into the calibrated target flux time series. Using a combination of raw science pixel data, full frame images, reverse-clocked pixel data and ancillary temperature data the Keplerpipeline models and removes the FGS crosstalk artifacts by dynamically adjusting the black level correction. By examining the residuals to the model fits, the pipeline detects and flags spatial regions and time intervals of strong time-varying blacklevel (rolling bands ) on a per row per cadence basis. These flags are made available to downstream users of the data since the uncorrected rolling band artifacts could complicate processing or lead to misinterpretation of instrument behavior as stellar. This model fitting and artifact flagging is performed within the new stand-alone pipeline model called Dynablack. We discuss the implementation of Dynablack in the Kepler data pipeline and present results regarding the improvement in calibrated pixels and the expected improvement in cotrending performances as a result of including FGS corrections in the calibration. We also discuss the effectiveness of the rolling band flagging for downstream users and illustrate with some affected light curves.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-25
...] Information Collection; Open Government Citizen Engagement Ratings, Rankings, and Flagging AGENCY: Office of... regarding open government citizen engagement ratings, rankings, and flagging. DATES: Comments must be...- 0288, Open Government Citizen Engagement Ratings, Rankings, and Flagging, by any of the following...
The WRKY transcription factor family and senescence in switchgrass.
Rinerson, Charles I; Scully, Erin D; Palmer, Nathan A; Donze-Reiner, Teresa; Rabara, Roel C; Tripathi, Prateek; Shen, Qingxi J; Sattler, Scott E; Rohila, Jai S; Sarath, Gautam; Rushton, Paul J
2015-11-09
Early aerial senescence in switchgrass (Panicum virgatum) can significantly limit biomass yields. WRKY transcription factors that can regulate senescence could be used to reprogram senescence and enhance biomass yields. All potential WRKY genes present in the version 1.0 of the switchgrass genome were identified and curated using manual and bioinformatic methods. Expression profiles of WRKY genes in switchgrass flag leaf RNA-Seq datasets were analyzed using clustering and network analyses tools to identify both WRKY and WRKY-associated gene co-expression networks during leaf development and senescence onset. We identified 240 switchgrass WRKY genes including members of the RW5 and RW6 families of resistance proteins. Weighted gene co-expression network analysis of the flag leaf transcriptomes across development readily separated clusters of co-expressed genes into thirteen modules. A visualization highlighted separation of modules associated with the early and senescence-onset phases of flag leaf growth. The senescence-associated module contained 3000 genes including 23 WRKYs. Putative promoter regions of senescence-associated WRKY genes contained several cis-element-like sequences suggestive of responsiveness to both senescence and stress signaling pathways. A phylogenetic comparison of senescence-associated WRKY genes from switchgrass flag leaf with senescence-associated WRKY genes from other plants revealed notable hotspots in Group I, IIb, and IIe of the phylogenetic tree. We have identified and named 240 WRKY genes in the switchgrass genome. Twenty three of these genes show elevated mRNA levels during the onset of flag leaf senescence. Eleven of the WRKY genes were found in hotspots of related senescence-associated genes from multiple species and thus represent promising targets for future switchgrass genetic improvement. Overall, individual WRKY gene expression profiles could be readily linked to developmental stages of flag leaves.
SERPent: Automated reduction and RFI-mitigation software for e-MERLIN
NASA Astrophysics Data System (ADS)
Peck, Luke W.; Fenech, Danielle M.
2013-08-01
The Scripted E-merlin Rfi-mitigation PipelinE for iNTerferometry (SERPent) is an automated reduction and RFI-mitigation procedure utilising the SumThreshold methodology (Offringa et al., 2010a), originally developed for the LOFAR pipeline. SERPent is written in the Parseltongue language enabling interaction with the Astronomical Image Processing Software (AIPS) program. Moreover, SERPent is a simple 'out of the box' Python script, which is easy to set up and is free of compilers. In addition to the flagging of RFI affected visibilities, the script also flags antenna zero-amplitude dropouts and Lovell telescope phase calibrator stationary scans inherent to the e-MERLIN system. Both the flagging and computational performances of SERPent are presented here, for e-MERLIN commissioning datasets for both L-band (1.3-1.8 GHz) and C-band (4-8 GHz) observations. RFI typically amounts to <20%-25% for the more problematic L-band observations and <5% for the generally RFI quieter C-band. The level of RFI detection and flagging is more accurate and delicate than visual manual flagging, with the output immediately ready for AIPS calibration. SERPent is fully parallelised and has been tested on a range of computing systems. The current flagging rate is at 110 GB day-1 on a 'high-end' computer (16 CPUs, 100 GB memory) which amounts to ˜6.9 GB CPU-1 day-1, with an expected increase in performance when e-MERLIN has completed its commissioning. The refining of automated reduction and calibration procedures is essential for the e-MERLIN legacy projects and future interferometers such as the SKA and the associated pathfinders (MeerKAT and ASKAP), where the vast data sizes (>TB) make traditional astronomer interactions unfeasible.
Burnham, Bruce R; Copley, G Bruce; Shim, Matthew J; Kemp, Philip A; Jones, Bruce H
2010-01-01
Flag (touch or intramural) football is a popular sport among the U.S. Air Force (USAF) active duty population and causes a substantial number of lost-workday injuries. The purpose of this study is to describe the mechanisms of flag-football injuries to better identify effective countermeasures. The data were derived from safety reports obtained from the USAF Ground Safety Automated System. Flag-football injuries for the years 1993-2002 that resulted in at least one lost workday were included in the study conducted in 2003. Narrative data were systematically reviewed for 32,812 USAF mishap reports; these were then coded in order to categorize and summarize mechanisms associated with flag football and other sports and occupational injuries. Nine hundred and forty-four mishap reports involving active duty USAF members playing flag football met the criteria for inclusion into this study. Eight mechanisms of injury were identified. The eight mechanisms accounted for 90% of all flag-football injuries. One scenario (contact with another player) accounted for 42% of all flag-football injuries. The most common mechanisms of injury caused by playing flag football can be identified using the detailed information found in safety reports. These scenarios are essential to developing evidence-based countermeasures. Results for flag football suggest that interventions that prevent player contact injuries deserve further research and evaluation. The broader implications of this study are that military safety data can be used to identify potentially modifiable mechanisms of injury for specific activities such as flag football. Published by Elsevier Inc.
76 FR 39885 - Risk-Based Targeting of Foreign Flagged Mobile Offshore Drilling Units (MODUs)
Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-07
... Foreign Flagged Mobile Offshore Drilling Units (MODUs) AGENCY: Coast Guard, DHS. ACTION: Notice of... 11-06, Risk-Based Targeting of Foreign Flagged Mobile Offshore Drilling Units (MODUs). This policy... applicable regulations, every foreign-flagged mobile offshore drilling unit (MODU) must undergo a Coast Guard...
78 FR 36311 - Flag Recognition Benefit for Fallen Federal Civilian Employees
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-17
... Recognition Benefit for Fallen Federal Civilian Employees; Submission for Review: Application for U.S. Flag... PERSONNEL MANAGEMENT 5 CFR Part 550 RIN 3206-AM58 Flag Recognition Benefit for Fallen Federal Civilian... United States flag recognition benefit for fallen Federal civilian employees, and describe the...
ERIC Educational Resources Information Center
Sumida, Anna
2000-01-01
Describes how a visit to the principal's office to see his family heirloom (a quilted Hawaiian flag), and reading the book "Badger's Parting Gifts," created powerful and ongoing lessons for the author's second graders, imparting an eternal way of thinking about gifts, family, friends, and human values. (SR)
Adversarial Geospatial Abduction Problems
2011-01-01
which is new , shows that #GCD is #P-complete and, moreover, that there is no fully-polynomial random approximation scheme for #GCD unless NP equals the...use L∗ to form a new set of constraints to find a δ-core optimal explanation. We now present these δ-core constraints. Notice that the cardinality...EXBrf (∅, efd), flag1 = true, i = 2 (4) While flag1 (a) new val = cur val + inci (b) If new val > (1 + |L|2 ) · cur val then i. If EXBrf (B ∪ {pi
Multiple-Frequency Ultrasonic Pulse-Echo Display System.
1982-09-28
will sweep across some time interval. Adjust the ramp rate potentiometer to set this interval to exactly 10 ps. Ramp Delay None Set time base to 1.0 lis...the function keys. The table is a printout which results F.irectly from exercising Program KEE, listed in Appendix C-I. Note that "(ESC)B" refers to...flag +21 ŕ" = one-time flag (nessage is presented prior to full plot once per session) +22 time- base duration code +23 (High order digit) +24 * +25
10 CFR 1002.3 - Custody of official seal and distinguishing flags.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 10 Energy 4 2011-01-01 2011-01-01 false Custody of official seal and distinguishing flags. 1002.3 Section 1002.3 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG General § 1002.3 Custody of official seal and distinguishing flags. The Secretary or his designee shall...
10 CFR 1002.3 - Custody of official seal and distinguishing flags.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false Custody of official seal and distinguishing flags. 1002.3 Section 1002.3 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG General § 1002.3 Custody of official seal and distinguishing flags. The Secretary or his designee shall...
Gransee, Heather M.; Zhan, Wen-Zhi; Sieck, Gary C.; Mantilla, Carlos B.
2013-01-01
Progressive recovery of rhythmic phrenic activity occurs over time after a spinal cord hemisection involving unilateral transection of anterolateral funiculi at C2 (SH). Brain-derived neurotrophic factor (BDNF) acting through its full-length tropomyosin related kinase receptor subtype B (TrkB.FL) contributes to neuroplasticity after spinal cord injury, but the specific cellular substrates remain unclear. We hypothesized that selectively targeting increased TrkB.FL expression to phrenic motoneurons would be sufficient to enhance recovery of rhythmic phrenic activity after SH. Several adeno-associated virus (AAV) serotypes expressing GFP were screened to determine specificity for phrenic motoneuron transduction via intrapleural injection in adult rats. GFP expression was present in the cervical spinal cord 3 weeks after treatment with AAV serotypes 7, 8, and 9, but not with AAV2, 6, or rhesus-10. Overall, AAV7 produced the most consistent GFP expression in phrenic motoneurons. SH was performed 3 weeks after intrapleural injection of AAV7 expressing human TrkB.FL-FLAG or saline. Delivery of TrkB.FL-FLAG to phrenic motoneurons was confirmed by FLAG protein expression in the phrenic motor nucleus and human TrkB.FL mRNA expression in microdissected phrenic motoneurons. In all SH rats, absence of ipsilateral diaphragm EMG activity was confirmed at 3 days post-SH, verifying complete interruption of ipsilateral descending drive to phrenic motoneurons. At 14 days post-SH, all AAV7-TrkB.FL treated rats (n = 11) displayed recovery of ipsilateral diaphragm EMG activity compared to 3 out of 8 untreated SH rats (p<0.01). During eupnea, AAV7-TrkB.FL treated rats exhibited 73±7% of pre-SH root mean squared EMG vs. only 31±11% in untreated SH rats displaying recovery (p<0.01). This study provides direct evidence that increased TrkB.FL expression in phrenic motoneurons is sufficient to enhance recovery of ipsilateral rhythmic phrenic activity after SH, indicating that selectively targeting gene expression in spared motoneurons below the level of spinal cord injury may promote functional recovery. PMID:23724091
2012-06-01
and the improper use of a flag of truce or of military insignia .50 The principle of humaneness has provided the foundation for international...Belsen refers to the Nazi concentration camp Bergen- Belsen. 135 more about war than we know about peace, more about killing than we know about
75 FR 34309 - Flag Day and National Flag Week, 2010
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-16
... Nation to confront tyranny and oppression still flies today as an unequivocal emblem of freedom and... gatherings to private memorials, we gathered to salute our flag, and in doing so, renewed the eternal promise... recognize the American flag as a symbol of hope and inspiration to people at home and around the world--as a...
2008-06-17
CAPE CANAVERAL, Fla. – 2008 Daytona 500 winner Ryan Newman leaves the Operations and Checkout Building at NASA's Kennedy Space Center, emulating the exit of shuttle crews before a launch. At left is Janet Petro, Kennedy's deputy center director. Behind them are Daytona International Speedway President Robin Braig (left) and Daytona 500 Experience General Manager Kim Isemann. Newman is visiting Kennedy in honor of NASA's 50th anniversary and the 50th running of NASCAR's Daytona 500 in February. NASA presented Newman two green racing flags that were flown last February aboard space shuttle Atlantis' STS-122 mission to the International Space Station. One flag was given to Newman, the second was presented to Daytona 500 Experience General Manager Kim Isemann. A third flag that was flown will be kept by NASA for public display. The connection between NASA and Daytona's International Speedway extends beyond their close proximity to one another. During recent years, technology developed for the space program has found many uses on Earth, including helping NASCAR drivers stay safe and increase performance. Photo credit: NASA/Kim Shiflett
2008-06-17
CAPE CANAVERAL, Fla. – 2008 Daytona 500 winner Ryan Newman (left) and Daytona International Speedway President Robin Braig talk to the media gathered on the crawlerway on Launch Pad 39A at NASA's Kennedy Space Center. The Daytona International Speedway show car, shown here, is in sharp contrast to the crawler-transporter that usually travels the special road to the pad. Newman is visiting Kennedy in honor of NASA's 50th anniversary and the 50th running of NASCAR's Daytona 500 in February. NASA presented Newman two green racing flags that were flown last February aboard space shuttle Atlantis' STS-122 mission to the International Space Station. One flag was given to Newman, the second was presented to Daytona 500 Experience General Manager Kim Isemann. A third flag that was flown will be kept by NASA for public display. The connection between NASA and Daytona's International Speedway extends beyond their close proximity to one another. During recent years, technology developed for the space program has found many uses on Earth, including helping NASCAR drivers stay safe and increase performance. Photo credit: NASA/Kim Shiflett
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-12
...) Increase the fee for orders yielding Flag K, which routes to NASDAQ OMX PSX (``PSX'') using ROUC or ROUE... for orders yielding Flag K, which routes to PSX using ROUC or ROUE routing strategies; and (ii) decrease the fee for orders yielding Flag RW, which routes to CBSX and adds liquidity. Flag K In securities...
3 CFR 8391 - Proclamation 8391 of June 11, 2009. Flag Day and National Flag Week, 2009
Code of Federal Regulations, 2010 CFR
2010-01-01
... America A Proclamation In the midst of a war for our Nation's independence, on June 14, 1777, the Second... America's promise and guides us toward a brighter tomorrow. To commemorate the adoption of our flag, the... toward equality and justice for all. Our flag's journey has been long. It has seen our Nation through war...
Red flag screening for low back pain: nothing to see here, move along: a narrative review.
Cook, Chad E; George, Steven Z; Reiman, Michael P
2018-04-01
Screening for red flags in individuals with low back pain (LBP) has been a historical hallmark of musculoskeletal management. Red flag screening is endorsed by most LBP clinical practice guidelines, despite a lack of support for their diagnostic capacity. We share four major reasons why red flag screening is not consistent with best practice in LBP management: (1) clinicians do not actually screen for red flags, they manage the findings; (2) red flag symptomology negates the utility of clinical findings; (3) the tests lack the negative likelihood ratio to serve as a screen; and (4) clinical practice guidelines do not include specific processes that aid decision-making. Based on these findings, we propose that clinicians consider: (1) the importance of watchful waiting; (2) the value-based care does not support clinical examination driven by red flag symptoms; and (3) the recognition that red flag symptoms may have a stronger relationship with prognosis than diagnosis. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Zhao, Zhenfu; Pu, Xiong; Du, Chunhua; Li, Linxuan; Jiang, Chunyan; Hu, Weiguo; Wang, Zhong Lin
2016-02-23
Wind energy at a high altitude is far more stable and stronger than that near the ground, but it is out of reach of the wind turbine. Herein, we develop an innovative freestanding woven triboelectric nanogenerator flag (WTENG-flag) that can harvest high-altitude wind energy from arbitrary directions. The wind-driven fluttering of the woven unit leads to the current generation by a coupled effect of contact electrification and electrostatic induction. Systematic study is conducted to optimize the structure/material parameters of the WTENG-flag to improve the power output. This 2D WTENG-flag can also be stacked in parallel connections in many layers for a linearly increased output. Finally, a self-powered high-altitude platform with temperature/humidity sensing/telecommunicating capability is demonstrated with the WTENG-flag as a power source. Due to the light weight, low cost, and easy scale-up, this WTENG-flag has great potential for applications in weather/environmental sensing/monitoring systems.
Grimes, Carolyn N; Fry, Michael M
2014-12-01
This study sought to develop customized morphology flagging thresholds for canine erythrocyte volume and hemoglobin concentration [Hgb] on the ADVIA 120 hematology analyzer; compare automated morphology flagging with results of microscopic blood smear evaluation; and examine effects of customized thresholds on morphology flagging results. Customized thresholds were determined using data from 52 clinically healthy dogs. Blood smear evaluation and automated morphology flagging results were correlated with mean cell volume (MCV) and cellular hemoglobin concentration mean (CHCM) in 26 dogs. Customized thresholds were applied retroactively to complete blood (cell) count (CBC) data from 5 groups of dogs, including a reference sample group, clinical cases, and animals with experimentally induced iron deficiency anemia. Automated morphology flagging correlated more highly with MCV or CHCM than did blood smear evaluation; correlation with MCV was highest using customized thresholds. Customized morphology flagging thresholds resulted in more sensitive detection of microcytosis, macrocytosis, and hypochromasia than default thresholds.
Method for compression of binary data
Berlin, Gary J.
1996-01-01
The disclosed method for compression of a series of data bytes, based on LZSS-based compression methods, provides faster decompression of the stored data. The method involves the creation of a flag bit buffer in a random access memory device for temporary storage of flag bits generated during normal LZSS-based compression. The flag bit buffer stores the flag bits separately from their corresponding pointers and uncompressed data bytes until all input data has been read. Then, the flag bits are appended to the compressed output stream of data. Decompression can be performed much faster because bit manipulation is only required when reading the flag bits and not when reading uncompressed data bytes and pointers. Uncompressed data is read using byte length instructions and pointers are read using word instructions, thus reducing the time required for decompression.
NASA Astrophysics Data System (ADS)
Zeilik, M.; Mathieu, R. D.; National InstituteScience Education; College Level-One Team
2000-12-01
Even the most dedicated college faculty often discover that their students fail to learn what was taught in their courses and that much of what students do learn is quickly forgotten after the final exam. To help college faculty improve student learning in college Science, Mathematics, Engineering and Technology (SMET), the College Level - One Team of the National Institute for Science Education has created the "FLAG" a Field-tested Learning Assessment Guide for SMET faculty. Developed with funding from the National Science Foundation, the FLAG presents in guidebook format a diverse and robust collection of field-tested classroom assessment techniques (CATs), with supporting information on how to apply them in the classroom. Faculty can download the tools and techniques from the website, which also provides a goals clarifier, an assessment primer, a searchable database, and links to additional resources. The CATs and tools have been reviewed by an expert editorial board and the NISE team. These assessment strategies can help faculty improve the learning environments in their SMET courses especially the crucial introductory courses that most strongly shape students' college learning experiences. In addition, the FLAG includes the web-based Student Assessment of Learning Gains. The SALG offers a convenient way to evaluate the impact of your courses on students. It is based on findings that students' estimates of what they gained are more reliable and informative than their observations of what they liked about the course or teacher. It offers accurate feedback on how well the different aspects of teaching helped the students to learn. Students complete the SALG online after a generic template has been modified to fit the learning objectives and activities of your course. The results are presented to the teacher as summary statistics automatically. The FLAG can be found at the NISE "Innovations in SMET Education" website at www.wcer.wisc.edu/nise/cl1
Commercial Sealift and U.S. National Security
2010-03-01
and maintaining a U.S. flag merchant marine fleet in today’s globalized shipping environment, where lower cost foreign flag registries of convenience ...in today’s globalized shipping environment, where lower cost foreign flag registries of convenience dominate the industry and which policy tools are...shipping environment, where lower cost foreign flag registries of convenience dominate the industry and which policy tools are best suited to meet our
American Colleges Raise the Flag in Vietnam
ERIC Educational Resources Information Center
Overland, Martha Ann
2009-01-01
More than 30 years after the U.S. ambassador was airlifted from the embassy rooftop in Saigon with the flag tucked under his arm, a new American flag is going up in the city. This one won't be flying over the embassy. The Stars and Stripes, as well as the Texas state flag, are going up at the Saigon Institute of Technology, the only Vietnamese…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-14
... PI, where Flag PI removes liquidity from the EDGX book against the Midpoint Match. This charge would signal a rate change for Flag PI if the conditions for achieving the Mega Tier \\4\\ are not satisfied. The Exchange also proposes to amend the text of Footnote 1 to add Flags BB and PI to the list of removal flags...
NASA Technical Reports Server (NTRS)
1991-01-01
Designed by the participating crewmembers, the STS-44 patch shows the Space Shuttle Atlantis ascending to Earth orbit to expand mankind's knowledge. The patch illustrated by the symbolic red, white and blue of the American flag represents the American contribution and strength derived from this mission. The black background of space, indicative of the mysteries of the universe, is illuminated by six large stars, which depict the American crew of six and the hopes that travel with them. The smaller stars represent Americans who work in support of this mission. Within the Shuttle's payload bay is a Defense Support Program Satellite which will help insure peace. In the words of a crew spokesman, the stars of the flag symbolize our leadership in an exciting quest of space and the boundless dreams for humanity's future.
Method for compression of binary data
Berlin, G.J.
1996-03-26
The disclosed method for compression of a series of data bytes, based on LZSS-based compression methods, provides faster decompression of the stored data. The method involves the creation of a flag bit buffer in a random access memory device for temporary storage of flag bits generated during normal LZSS-based compression. The flag bit buffer stores the flag bits separately from their corresponding pointers and uncompressed data bytes until all input data has been read. Then, the flag bits are appended to the compressed output stream of data. Decompression can be performed much faster because bit manipulation is only required when reading the flag bits and not when reading uncompressed data bytes and pointers. Uncompressed data is read using byte length instructions and pointers are read using word instructions, thus reducing the time required for decompression. 5 figs.
Rift Valley Fever Risk Map Model and Seroprevalence in Selected Wild Ungulates and Camels from Kenya
Ruder, Mark G.; Linthicum, Kenneth J.; Anyamba, Assaf; Small, Jennifer L.; Tucker, Compton J.; Ateya, Leonard O.; Oriko, Abuu A.; Gacheru, Stephen; Wilson, William C.
2013-01-01
Since the first isolation of Rift Valley fever virus (RVFV) in the 1930s, there have been multiple epizootics and epidemics in animals and humans in sub-Saharan Africa. Prospective climate-based models have recently been developed that flag areas at risk of RVFV transmission in endemic regions based on key environmental indicators that precede Rift Valley fever (RVF) epizootics and epidemics. Although the timing and locations of human case data from the 2006–2007 RVF outbreak in Kenya have been compared to risk zones flagged by the model, seroprevalence of RVF antibodies in wildlife has not yet been analyzed in light of temporal and spatial predictions of RVF activity. Primarily wild ungulate serum samples from periods before, during, and after the 2006–2007 RVF epizootic were analyzed for the presence of RVFV IgM and/or IgG antibody. Results show an increase in RVF seropositivity from samples collected in 2007 (31.8%), compared to antibody prevalence observed from 2000–2006 (3.3%). After the epizootic, average RVF seropositivity diminished to 5% in samples collected from 2008–2009. Overlaying maps of modeled RVF risk assessments with sampling locations indicated positive RVF serology in several species of wild ungulate in or near areas flagged as being at risk for RVF. Our results establish the need to continue and expand sero-surveillance of wildlife species Kenya and elsewhere in the Horn of Africa to further calibrate and improve the RVF risk model, and better understand the dynamics of RVFV transmission. PMID:23840512
Rift Valley Fever Risk Map Model and Seroprevalence in Selected Wild Ungulates and Camels from Kenya
NASA Technical Reports Server (NTRS)
Britch, Seth C.; Binepal, Yatinder S.; Ruder, Mark G.; Kariithi, Henry M.; Linthicum, Kenneth J.; Anyamba, Assaf; Small, Jennifer L.; Tucker, Compton J.; Ateya, Leonard O.; Oriko, Abuu A.;
2013-01-01
Since the first isolation of Rift Valley fever virus (RVFV) in the 1930s, there have been multiple epizootics and epidemics in animals and humans in sub-Saharan Africa. Prospective climate-based models have recently been developed that flag areas at risk of RVFV transmission in endemic regions based on key environmental indicators that precede Rift Valley fever (RVF) epizootics and epidemics. Although the timing and locations of human case data from the 2006-2007 RVF outbreak in Kenya have been compared to risk zones flagged by the model, seroprevalence of RVF antibodies in wildlife has not yet been analyzed in light of temporal and spatial predictions of RVF activity. Primarily wild ungulate serum samples from periods before, during, and after the 2006-2007 RVF epizootic were analyzed for the presence of RVFV IgM and/or IgG antibody. Results show an increase in RVF seropositivity from samples collected in 2007 (31.8%), compared to antibody prevalence observed from 2000-2006 (3.3%). After the epizootic, average RVF seropositivity diminished to 5% in samples collected from 2008-2009. Overlaying maps of modeled RVF risk assessments with sampling locations indicated positive RVF serology in several species of wild ungulate in or near areas flagged as being at risk for RVF. Our results establish the need to continue and expand sero-surveillance of wildlife species Kenya and elsewhere in the Horn of Africa to further calibrate and improve the RVF risk model, and better understand the dynamics of RVFV transmission.
Vertical Feature Mask Feature Classification Flag Extraction
Atmospheric Science Data Center
2013-03-28
Vertical Feature Mask Feature Classification Flag Extraction This routine demonstrates extraction of the ... in a CALIPSO Lidar Level 2 Vertical Feature Mask feature classification flag value. It is written in Interactive Data Language (IDL) ...
Thode, Aaron M; Kim, Katherine H; Blackwell, Susanna B; Greene, Charles R; Nations, Christopher S; McDonald, Trent L; Macrander, A Michael
2012-05-01
An automated procedure has been developed for detecting and localizing frequency-modulated bowhead whale sounds in the presence of seismic airgun surveys. The procedure was applied to four years of data, collected from over 30 directional autonomous recording packages deployed over a 280 km span of continental shelf in the Alaskan Beaufort Sea. The procedure has six sequential stages that begin by extracting 25-element feature vectors from spectrograms of potential call candidates. Two cascaded neural networks then classify some feature vectors as bowhead calls, and the procedure then matches calls between recorders to triangulate locations. To train the networks, manual analysts flagged 219 471 bowhead call examples from 2008 and 2009. Manual analyses were also used to identify 1.17 million transient signals that were not whale calls. The network output thresholds were adjusted to reject 20% of whale calls in the training data. Validation runs using 2007 and 2010 data found that the procedure missed 30%-40% of manually detected calls. Furthermore, 20%-40% of the sounds flagged as calls are not present in the manual analyses; however, these extra detections incorporate legitimate whale calls overlooked by human analysts. Both manual and automated methods produce similar spatial and temporal call distributions.
NASA Astrophysics Data System (ADS)
Poeppl, Ronald E.; Keesstra, Saskia D.; Maroulis, Jerry
2017-01-01
Human-induced landscape change is difficult to predict due to the complexity inherent in both geomorphic and social systems as well as due to the coupling relationships between them. To better understand system complexity and system response to changing inputs, "connectivity thinking" has become an important recent paradigm within various disciplines including ecology, hydrology and geomorphology. With the presented conceptual connectivity framework on geomorphic change in human-impacted fluvial systems a cautionary note is flagged regarding the need (i) to include and to systematically conceptualise the role of different types of human agency in altering connectivity relationships in geomorphic systems and (ii) to integrate notions of human-environment interactions to connectivity concepts in geomorphology to better explain causes and trajectories of landscape change. Geomorphic response of fluvial systems to human disturbance is shown to be determined by system-specific boundary conditions (incl. system history, related legacy effects and lag times), vegetation dynamics and human-induced functional relationships (i.e. feedback mechanisms) between the different spatial dimensions of connectivity. It is further demonstrated how changes in social systems can trigger a process-response feedback loop between social and geomorphic systems that further governs the trajectory of landscape change in coupled human-geomorphic systems.
Heritage or Hate? A Pedagogical Guide to the Confederate Flag in Post-Race America
ERIC Educational Resources Information Center
Lippard, Cameron D.
2017-01-01
The Confederate flag has been a hotly debated symbol of heritage or hate in the United States. In 2015, 54 per cent of Americans polled saw the flag as a symbol of 'Southern pride' whereas 34 per cent saw it as racist. However, 27 per cent of Whites compared to 69 per cent of Blacks saw the flag as racist. In this article, I suggest how…
Interaction of in-phase and out-of-phase flexible filament in fish schooling
NASA Astrophysics Data System (ADS)
Ud Din, Emad; Sung, Hyung
2011-11-01
Fish schooling is not merely a social behavior; schooling improves the efficiency of movement within the fluid environment. Inspired by the schooling from a hydrodynamic perspective, a group of aquatic animals is modeled as a collection of individuals arranged in a combination of tandem and side-by-side (diamond) formation. The downstream bodies are strongly influenced by the vortices shed by the upstream body shown by vortex-vortex and vortex-body interactions. Trailing fish takes advantage of this flow pattern for energy economy. To investigate the interactions between flexible bodies and vortices, in the present study three flexible flags in viscous flow are solved by numerical simulation using an improved version of the immersed boundary method for in-phase and out-of-phase filaments. The drag coefficient of the downstream filaments drops even below the value of a single flag. Such drag variations are influenced by the interactions between vortices shed by the upstream flexible body and vortices surrounding the downstream filaments. Interaction of the flexible flags is investigated as a function of the gap distance between flags and different bending coefficients, for in-phase and out-of-phase cases at intermediate Reynolds numbers. This study was supported by the Creative Research Initiatives of NRF/MEST (No. 2011-0000423) of Korea.
Jiang, Lide; Wang, Menghua
2013-09-20
A new flag/masking scheme has been developed for identifying stray light and cloud shadow pixels that significantly impact the quality of satellite-derived ocean color products. Various case studies have been carried out to evaluate the performance of the new cloud contamination flag/masking scheme on ocean color products derived from the Visible Infrared Imaging Radiometer Suite (VIIRS) onboard the Suomi National Polar-orbiting Partnership (SNPP). These include direct visual assessments, detailed quantitative case studies, objective statistic analyses, and global image examinations and comparisons. The National Oceanic and Atmospheric Administration (NOAA) Multisensor Level-1 to Level-2 (NOAA-MSL12) ocean color data processing system has been used in the study. The new stray light and cloud shadow identification method has been shown to outperform the current stray light flag in both valid data coverage and data quality of satellite-derived ocean color products. In addition, some cloud-related flags from the official VIIRS-SNPP data processing software, i.e., the Interface Data Processing System (IDPS), have been assessed. Although the data quality with the IDPS flags is comparable to that of the new flag implemented in the NOAA-MSL12 ocean color data processing system, the valid data coverage from the IDPS is significantly less than that from the NOAA-MSL12 using the new stray light and cloud shadow flag method. Thus, the IDPS flag/masking algorithms need to be refined and modified to reduce the pixel loss, e.g., the proposed new cloud contamination flag/masking can be implemented in IDPS VIIRS ocean color data processing.
Defense.gov Special Report: Travels with Hagel
Afghanistan Flag of Pakistan Flag of Saudi Arabia Flag of Qatar December 2013 News Stories Hagel Concludes Six -day Troop, Partner Nation Visits Defense Secretary Chuck Hagel wrapped up a six-day trip to the Middle
2008-06-17
CAPE CANAVERAL, Fla. – Members of the media stretch across the crawlerway on Launch Pad 39A at NASA's Kennedy Space Center to interview 2008 Daytona 500 winner Ryan Newman (center right). At left is Daytona International Speedway President Robin Braig. The Daytona International Speedway show car, shown here, is in sharp contrast to the crawler-transporter that usually travels the special road to the pad at a maximum speed of 2 mph. Newman is visiting Kennedy in honor of NASA's 50th anniversary and the 50th running of NASCAR's Daytona 500 in February. NASA presented Newman two green racing flags that were flown last February aboard space shuttle Atlantis' STS-122 mission to the International Space Station. One flag was given to Newman, the second was presented to Daytona 500 Experience General Manager Kim Isemann. A third flag that was flown will be kept by NASA for public display. The connection between NASA and Daytona's International Speedway extends beyond their close proximity to one another. During recent years, technology developed for the space program has found many uses on Earth, including helping NASCAR drivers stay safe and increase performance. Photo credit: NASA/Kim Shiflett
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. -- Former astronaut Winston Scott (left) presents a NASA flag flown at the KSC Space Life Sciences Lab to NASA Administrator Sean OKeefe. The flag was flown during construction through the dedication of the Lab. The presentation was during a tour of the Lab following the launching ceremony at the KSC Visitor Complex for the new Florida quarter issued by the U.S. Mint. The ceremony was emceed by Center Director Jim Kennedy and included remarks by OKeefe, Florida Gov. Jeb Bush, U.S. Mint Director Henrietta Holsman Fore and Deputy Secretary of the Treasury Samuel W. Bodman. The new lab is a state-of-the-art facility built for ISS biotechnology research. It was developed as a partnership between NASA-KSC and the State of Florida.
2004-04-07
KENNEDY SPACE CENTER, FLA. -- Center Director Jim Kennedy presents a Florida flag to Florida Gov. Jeb Bush. The flag was flown during construction of the Space Life Sciences Lab through dedication of the Lab. The presentation was during a tour of the Lab following the launching ceremony at the KSC Visitor Complex for the new Florida quarter issued by the U.S. Mint. The ceremony was emceed by Center Director Jim Kennedy and included remarks by NASA Administrator Sean O’Keefe, Bush, U.S. Mint Director Henrietta Holsman Fore and Deputy Secretary of the Treasury Samuel W. Bodman. The new lab is a state-of-the-art facility built for ISS biotechnology research. It was developed as a partnership between NASA-KSC and the State of Florida.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. -- Former astronaut Winston Scott (left) presents a NASA flag flown at the KSC Space Life Sciences Lab to NASA Administrator Sean OKeefe. The flag was flown during construction through the dedication of the Lab. The presentation was during a tour of the Lab following the launching ceremony at the KSC Visitor Complex for the new Florida quarter issued by the U.S. Mint. The ceremony was emceed by Center Director Jim Kennedy and included remarks by OKeefe, Florida Gov. Jeb Bush, U.S. Mint Director Henrietta Holsman Fore and Deputy Secretary of the Treasury Samuel W. Bodman. The new lab is a state-of-the-art facility built for ISS biotechnology research. It was developed as a partnership between NASA-KSC and the State of Florida.
NASA Technical Reports Server (NTRS)
2004-01-01
KENNEDY SPACE CENTER, FLA. -- Center Director Jim Kennedy presents a Florida flag to Florida Gov. Jeb Bush. The flag was flown during construction of the Space Life Sciences Lab through dedication of the Lab. The presentation was during a tour of the Lab following the launching ceremony at the KSC Visitor Complex for the new Florida quarter issued by the U.S. Mint. The ceremony was emceed by Center Director Jim Kennedy and included remarks by NASA Administrator Sean OKeefe, Bush, U.S. Mint Director Henrietta Holsman Fore and Deputy Secretary of the Treasury Samuel W. Bodman. The new lab is a state-of-the-art facility built for ISS biotechnology research. It was developed as a partnership between NASA-KSC and the State of Florida.
Code of Federal Regulations, 2010 CFR
2010-10-01
... bulk cargo shall display a red flag by day or a red light by night, which signal shall be so placed... display a red flag by day, placed so that it will be visible on all sides. This flag may be metallic. ...
Guidelines for the specification of blue safety flags in railroad operations
DOT National Transportation Integrated Search
2010-12-01
Blue flag protection in the railroad industry provides safety to workers from the inadvertent movement of equipment on which they : are working. Current Federal regulations provide minimum specifications for the devices that can be used as blue flags...
10 CFR 1.55 - Establishment of official NRC flag.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 1 2010-01-01 2010-01-01 false Establishment of official NRC flag. 1.55 Section 1.55 Energy NUCLEAR REGULATORY COMMISSION STATEMENT OF ORGANIZATION AND GENERAL INFORMATION NRC Seal and Flag... dark blue field with a gold fringe. ...
3 CFR 8993 - Proclamation 8993 of June 7, 2013. Flag Day and National Flag Week, 2013
Code of Federal Regulations, 2014 CFR
2014-01-01
... States to display the flag during that week. NOW, THEREFORE, I, BARACK OBAMA, President of the United... of the Independence of the United States of America the two hundred and thirty-seventh.BARACK OBAMA ...
Analyzing the Greek Marine Manpower in the Passenger and Cruise Markets Using System Dynamics
NASA Astrophysics Data System (ADS)
Alexopoulos, A. B.; Konstantopoulos, Nikolaos
2007-12-01
This The authors have applied the methodology of system dynamics modeling and simulation in the study of the depletion of the Greek maritime workforce with respect to parameters such as the flagging out rate from the Greek flag, the national maritime policy on the proportion of Greek and foreign seamen onboard Greek ships and the investment in seamen's life-long training, as well as in improving the safety and quality of Greek ships. This work is in progress and this paper presents an initial approach to the problem, as well as some first insights gained.
International Space Station (ISS)
2001-02-01
The International Space Station (ISS) Payload Operations Center (POC) at NASA's Marshall Space Flight Center (MSFC) in Huntsville, Alabama, is the world's primary science command post for the International Space Station (ISS), the most ambitious space research facility in human history. The Payload Operations team is responsible for managing all science research experiments aboard the Station. The center is also home for coordination of the mission-plarning work of variety of international sources, all science payload deliveries and retrieval, and payload training and safety programs for the Station crew and all ground personnel. Within the POC, critical payload information from the ISS is displayed on a dedicated workstation, reading both S-band (low data rate) and Ku-band (high data rate) signals from a variety of experiments and procedures operated by the ISS crew and their colleagues on Earth. The POC is the focal point for incorporating research and experiment requirements from all international partners into an integrated ISS payload mission plan. This photograph is an overall view of the MSFC Payload Operations Center displaying the flags of the countries participating the ISS. The flags at the left portray The United States, Canada, France, Switzerland, Netherlands, Japan, Brazil, and Sweden. The flags at the right portray The Russian Federation, Italy, Germany, Belgium, Spain, United Kingdom, Denmark, and Norway.
International Space Station (ISS)
2000-02-01
The International Space Station (ISS) Payload Operations Center (POC) at NASA's Marshall Space Flight Center (MSFC) in Huntsville, Alabama, is the world's primary science command post for the (ISS), the most ambitious space research facility in human history. The Payload Operations team is responsible for managing all science research experiments aboard the Station. The center is also home for coordination of the mission-plarning work of variety of international sources, all science payload deliveries and retrieval, and payload training and safety programs for the Station crew and all ground personnel. Within the POC, critical payload information from the ISS is displayed on a dedicated workstation, reading both S-band (low data rate) and Ku-band (high data rate) signals from a variety of experiments and procedures operated by the ISS crew and their colleagues on Earth. The POC is the focal point for incorporating research and experiment requirements from all international partners into an integrated ISS payload mission plan. This photograph is an overall view of the MSFC Payload Operations Center displaying the flags of the countries participating in the ISS. The flags at the left portray The United States, Canada, France, Switzerland, Netherlands, Japan, Brazil, and Sweden. The flags at the right portray The Russian Federation, Italy, Germany, Belgium, Spain, United Kingdom, Denmark, and Norway.
2011-02-18
CAPE CANAVERAL, Fla. -- "The National 9/11 Flag" is folded in the Rocket Garden at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
2011-02-18
CAPE CANAVERAL, Fla. -- "The National 9/11 Flag" is on display in the Debus Conference Facility at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
2011-02-18
CAPE CANAVERAL, Fla. -- "The National 9/11 Flag" is raised in the Rocket Garden at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
NASA Technical Reports Server (NTRS)
Riha, Andrew P.
2005-01-01
As humans and robotic technologies are deployed in future constellation systems, differing traffic services will arise, e.g., realtime and non-realtime. In order to provide a quality of service framework that would allow humans and robotic technologies to interoperate over a wide and dynamic range of interactions, a method of classifying data as realtime or non-realtime is needed. In our paper, we present an approach that leverages the Consultative Committee for Space Data Systems (CCSDS) Advanced Orbiting Systems (AOS) data link protocol. Specifically, we redefine the AOS Transfer Frame Replay Flag in order to provide an automated store-and-forward approach on a per-service basis for use in the next-generation Interplanetary Network. In addition to addressing the problem of intermittent connectivity and associated services, we propose a follow-on methodology for prioritizing data through further modification of the AOS Transfer Frame.
77 FR 20098 - Inventory of U.S.-Flag Launch Barges
Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-03
... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2012 0034] Inventory of U.S.-Flag Launch Barges AGENCY: Maritime Administration, Department of Transportation. ACTION: Inventory of U.S.-Flag Launch Barges. SUMMARY: The Maritime Administration is updating its inventory of U.S...
75 FR 13645 - Inventory of U.S.-Flag Launch Barges
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-22
... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2010 0023] Inventory of U.S.-Flag Launch Barges AGENCY: Maritime Administration, Department of Transportation. ACTION: Inventory of U.S.-Flag Launch Barges. SUMMARY: The Maritime Administration is updating its inventory of U.S...
Visual reproduction subtest of the Wechsler Memory Scale-Revised: analysis of construct validity.
Williams, M A; Rich, M A; Reed, L K; Jackson, W T; LaMarche, J A; Boll, T J
1998-11-01
This study assessed the construct validity of Visual Reproduction (VR) Cards A (Flags) and B (Boxes) from the original Wechsler Memory Scale (WMS) compared to Flags and Boxes from the revised edition of the WMS (WMS-R). Independent raters scored Flags and Boxes using both the original and revised scoring criteria and correlations were obtained with age, education, IQ, and four separate criterion memory measures. Results show that for Flags, there is a tendency for the revised scoring criteria to produce improved construct validity. For Boxes, however, there was a trend in the opposite direction, with the revised scoring criteria demonstrating worse construct validity. Factor analysis suggests that Flags are a more distinct measure of visual memory, whereas Boxes are more complex and significantly associated with conceptual reasoning abilities. Using the revised scoring criteria, Boxes were found to be more strongly related to IQ than Flags. This difference was not found using the original scoring criteria.
FLAG - APOLLO XI - ASTRONAUTS - MOON
1969-07-14
S69-39333 (July 1969) --- This is a photographic illustration of how the flag of the United States will be implanted on the moon by the Apollo 11 astronauts. The flag is three by five feet, and is made of nylon. It will be erected on an eight-foot aluminum staff, and tubing along its top edge will unfurl it in the airless environment of the moon. The implanting of the flag is symbolic of the first time man has landed on another celestial body, and does not constitute a territorial claim by the United States. The photograph on the right shows the flag in a furled condition. Apollo 11 astronauts Neil A. Armstrong, commander; and Edwin E. Aldrin Jr., lunar module pilot, will implant the flag after their Lunar Module (LM) sets down on the moon. Astronaut Michael Collins, command module pilot, will remain with the Command and Service Modules (CSM) in lunar orbit while Armstrong and Aldrin explore the lunar surface.
2016-05-03
Charlie Lundquist, NASA Orion deputy program manager, right, presents an American flag flown aboard the Orion capsule during the Exploration Flight Test-1 mission to Armstrong Deputy Director Patrick Stoliker.
Implementation of Human Trafficking Education and Treatment Algorithm in the Emergency Department.
Egyud, Amber; Stephens, Kimberly; Swanson-Bierman, Brenda; DiCuccio, Marge; Whiteman, Kimberly
2017-11-01
Health care professionals have not been successful in recognizing or rescuing victims of human trafficking. The purpose of this project was to implement a screening system and treatment algorithm in the emergency department to improve the identification and rescue of victims of human trafficking. The lack of recognition by health care professionals is related to inadequate education and training tools and confusion with other forms of violence such as trauma and sexual assault. A multidisciplinary team was formed to assess the evidence related to human trafficking and make recommendations for practice. After receiving education, staff completed a survey about knowledge gained from the training. An algorithm for identification and treatment of sex trafficking victims was implemented and included a 2-pronged identification approach: (1) medical red flags created by a risk-assessment tool embedded in the electronic health record and (2) a silent notification process. Outcome measures were the number of victims who were identified either by the medical red flags or by silent notification and were offered and accepted intervention. Survey results indicated that 75% of participants reported that the education improved their competence level. The results demonstrated that an education and treatment algorithm may be an effective strategy to improve recognition. One patient was identified as an actual victim of human trafficking; the remaining patients reported other forms of abuse. Education and a treatment algorithm were effective strategies to improve recognition and rescue of human trafficking victims and increase identification of other forms of abuse. Copyright © 2017 Emergency Nurses Association. Published by Elsevier Inc. All rights reserved.
Cyber Vigilance: The Human Factor
2016-10-21
88ABW-2014-5661; American Intelligence Journal 14. Cyber-defenders face lengthy, repetitive work assignments with few critical signals and little...research is inadvisable. To understand this unique domain, we asked participants to perform a simulated cybersecurity task, searching for attack...detection. To avoid this, IDS detection algorithms are purposely liberal, broadly flagging any activity that resembles a known American Intelligence
Rift Valley fever risk map model and seroprevalence in selected wild ungulates and camels from Kenya
USDA-ARS?s Scientific Manuscript database
Since the first isolation of Rift Valley fever virus (RVFV) in the 1930s, there have been multiple epizootics and epidemics in animals and humans in sub-Saharan Africa. Prospective climate-based models have recently been developed that flag areas at risk of RVFV transmission in endemic regions based...
46 CFR 154.22 - Foreign flag vessel: Certificate of Compliance endorsement application.
Code of Federal Regulations, 2010 CFR
2010-10-01
... requesting an endorsement for the carriage of ethylene oxide, a classification society certification that the... Commanding Officer, Marine Safety Center the plans, calculations, and information under § 154.15(b). [CGD 77... foreign flag vessel, whose flag administration issues IMO Certificates, must submit to the Commanding...
Code of Federal Regulations, 2010 CFR
2010-01-01
... and rest requirements: Domestic, flag, and supplemental operations. 121.467 Section 121.467..., Flag, and Supplemental Operations § 121.467 Flight attendant duty period limitations and rest... attendant's home station, is not considered part of a rest period. (13) Each certificate holder conducting...
36 CFR 504.9 - Placards, signs, banners and flags.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Placards, signs, banners and flags. 504.9 Section 504.9 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND REGULATIONS GOVERNING SMITHSONIAN INSTITUTION BUILDINGS AND GROUNDS § 504.9 Placards, signs, banners and flags...
48 CFR 47.403-3 - Disallowance of expenditures.
Code of Federal Regulations, 2010 CFR
2010-10-01
... CONTRACT MANAGEMENT TRANSPORTATION Air Transportation by U.S.-Flag Carriers 47.403-3 Disallowance of... air transportation on foreign-flag air carriers unless there is attached to the appropriate voucher a memorandum adequately explaining why service by U.S.-flag air carriers was not available, or why it was...
49 CFR 218.37 - Flag protection.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 49 Transportation 4 2010-10-01 2010-10-01 false Flag protection. 218.37 Section 218.37..., DEPARTMENT OF TRANSPORTATION RAILROAD OPERATING PRACTICES Protection of Trains and Locomotives § 218.37 Flag protection. (a) After August 1, 1977, each railroad must have in effect an operating rule which complies with...
36 CFR 520.10 - Placards, signs, banners, and flags.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Placards, signs, banners, and flags. 520.10 Section 520.10 Parks, Forests, and Public Property SMITHSONIAN INSTITUTION RULES AND... § 520.10 Placards, signs, banners, and flags. The displaying or carrying of placards, signs, banners, or...
2002-01-01
On platforms suspended from the top of the 525-foot-high VAB, workers use rollers and brushes to repaint the U.S. flag on the southwest side of the Vehicle Assembly Building. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo is also being painted. Known as the "meatball," the logo measures 110 feet by 132 feet, or about 12,300 square feet. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary.
2011-02-18
CAPE CANAVERAL, Fla. -- "The National 9/11 Flag" is transported from the Debus Conference Facility to the Rocket Garden at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
2011-02-18
CAPE CANAVERAL, Fla. -- "The National 9/11 Flag" is transported from the Debus Conference Facility to the Rocket Garden at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
2011-02-18
CAPE CANAVERAL, Fla. -- More than a dozen 9/11 first responders take part in "The National 9/11 Flag" stitching ceremony at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
NASA Technical Reports Server (NTRS)
Abbott, Mark R.
1997-01-01
We are responsible for the delivery of two at-launch products for AM-1: Fluorescence line height (FLH) and chlorophyll fluorescence efficiency (CFE). In our last report we had planned to combine the two separate algorithms into a single piece of code. However, after discussions with Bob Evans, it was decided that it was best to leave the two algorithms separate. They have been integrated into the MOCEAN processing system, and given their low computational requirements, it easier to keep them separate. In addition, there remain questions concerning the specific chlorophyll product that will be used for the CFE calculation. Presently, the CFE algorithm relies on the chlorophyll product produced by Ken Carder. This product is based on a reflectance model, and is theoretically different than the chlorophyll product being provided by Dennis Clark (NOAA). These two products will be compared systematically in the coming months. If we decide to switch to the Clark product, then it will be simpler to modify the CFE algorithm if it remains separate from the FLH algorithm. Our focus for the next six months is to refine the quality flags that were delivered as part of the algorithm last summer. A description of these flags was provided to Evans for the MOCEAN processing system. A summary was included in the revised ATBD. Some of the flags depend on flags produced by the input products so coordination will be required.
Ethical tissue: a not-for-profit model for human tissue supply.
Adams, Kevin; Martin, Sandie
2011-02-01
Following legislative changes in 2004 and the establishment of the Human Tissue Authority, access to human tissues for biomedical research became a more onerous and tightly regulated process. Ethical Tissue was established to meet the growing demand for human tissues, using a process that provided ease of access by researchers whilst maintaining the highest ethical and regulatory standards. The establishment of a licensed research tissue bank entailed several key criteria covering ethical, legal, financial and logistical issues being met. A wide range of stakeholders, including the HTA, University of Bradford, flagged LREC, hospital trusts and clinical groups were also integral to the process.
Genetic dissection and validation of candidate genes for flag leaf size in rice (Oryza sativa L.).
Tang, Xinxin; Gong, Rong; Sun, Wenqiang; Zhang, Chaopu; Yu, Sibin
2018-04-01
Two major loci with functional candidate genes were identified and validated affecting flag leaf size, which offer desirable genes to improve leaf architecture and photosynthetic capacity in rice. Leaf size is a major determinant of plant architecture and yield potential in crops. However, the genetic and molecular mechanisms regulating leaf size remain largely elusive. In this study, quantitative trait loci (QTLs) for flag leaf length and flag leaf width in rice were detected with high-density single nucleotide polymorphism genotyping of a chromosomal segment substitution line (CSSL) population, in which each line carries one or a few chromosomal segments from the japonica cultivar Nipponbare in a common background of the indica variety Zhenshan 97. In total, 14 QTLs for flag leaf length and nine QTLs for flag leaf width were identified in the CSSL population. Among them, qFW4-2 for flag leaf width was mapped to a 37-kb interval, with the most likely candidate gene being the previously characterized NAL1. Another major QTL for both flag leaf width and length was delimited by substitution mapping to a small region of 13.5 kb that contains a single gene, Ghd7.1. Mutants of Ghd7.1 generated using CRISPR/CAS9 approach showed reduced leaf size. Allelic variation analyses also validated Ghd7.1 as a functional candidate gene for leaf size, photosynthetic capacity and other yield-related traits. These results provide useful genetic information for the improvement of leaf size and yield in rice breeding programs.
14 CFR 121.601 - Aircraft dispatcher information to pilot in command: Domestic and flag operations.
Code of Federal Regulations, 2011 CFR
2011-01-01
... command: Domestic and flag operations. 121.601 Section 121.601 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.601 Aircraft dispatcher information to pilot in command: Domestic and flag operations. (a) The aircraft dispatcher shall provide the pilot in command all available current reports or...
14 CFR 121.601 - Aircraft dispatcher information to pilot in command: Domestic and flag operations.
Code of Federal Regulations, 2013 CFR
2013-01-01
... command: Domestic and flag operations. 121.601 Section 121.601 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.601 Aircraft dispatcher information to pilot in command: Domestic and flag operations. (a) The aircraft dispatcher shall provide the pilot in command all available current reports or...
14 CFR 121.601 - Aircraft dispatcher information to pilot in command: Domestic and flag operations.
Code of Federal Regulations, 2012 CFR
2012-01-01
... command: Domestic and flag operations. 121.601 Section 121.601 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.601 Aircraft dispatcher information to pilot in command: Domestic and flag operations. (a) The aircraft dispatcher shall provide the pilot in command all available current reports or...
14 CFR 121.601 - Aircraft dispatcher information to pilot in command: Domestic and flag operations.
Code of Federal Regulations, 2014 CFR
2014-01-01
... command: Domestic and flag operations. 121.601 Section 121.601 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.601 Aircraft dispatcher information to pilot in command: Domestic and flag operations. (a) The aircraft dispatcher shall provide the pilot in command all available current reports or...
14 CFR 121.601 - Aircraft dispatcher information to pilot in command: Domestic and flag operations.
Code of Federal Regulations, 2010 CFR
2010-01-01
... command: Domestic and flag operations. 121.601 Section 121.601 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.601 Aircraft dispatcher information to pilot in command: Domestic and flag operations. (a) The aircraft dispatcher shall provide the pilot in command all available current reports or...
14 CFR 121.641 - Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations.
Code of Federal Regulations, 2014 CFR
2014-01-01
...-powered airplanes: Flag operations. 121.641 Section 121.641 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.641 Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations. (a) No person may dispatch or take off a nonturbine or turbo-propeller-powered airplane unless...
14 CFR 121.641 - Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations.
Code of Federal Regulations, 2012 CFR
2012-01-01
...-powered airplanes: Flag operations. 121.641 Section 121.641 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.641 Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations. (a) No person may dispatch or take off a nonturbine or turbo-propeller-powered airplane unless...
14 CFR 121.641 - Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations.
Code of Federal Regulations, 2013 CFR
2013-01-01
...-powered airplanes: Flag operations. 121.641 Section 121.641 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.641 Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations. (a) No person may dispatch or take off a nonturbine or turbo-propeller-powered airplane unless...
14 CFR 121.641 - Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations. 121.641 Section 121.641 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.641 Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag...
14 CFR 121.641 - Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag operations. 121.641 Section 121.641 Aeronautics and Space FEDERAL AVIATION... Flight Release Rules § 121.641 Fuel supply: Nonturbine and turbo-propeller-powered airplanes: Flag...
77 FR 35807 - Flag Day and National Flag Week, 2012
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-15
.... Generations of service members have raised our country's colors over military bases and at sea, and... Day and National Flag Week, 2012 By the President of the United States of America A Proclamation... Woodrow Wilson asked us to ``stand with united hearts for an America which no man can corrupt, no...
14 CFR 121.621 - Alternate airport for destination: Flag operations.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Alternate airport for destination: Flag... § 121.621 Alternate airport for destination: Flag operations. (a) No person may dispatch an airplane under IFR or over-the-top unless he lists at least one alternate airport for each destination airport in...
14 CFR 121.621 - Alternate airport for destination: Flag operations.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Alternate airport for destination: Flag... § 121.621 Alternate airport for destination: Flag operations. (a) No person may dispatch an airplane under IFR or over-the-top unless he lists at least one alternate airport for each destination airport in...
14 CFR 121.621 - Alternate airport for destination: Flag operations.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Alternate airport for destination: Flag... § 121.621 Alternate airport for destination: Flag operations. (a) No person may dispatch an airplane under IFR or over-the-top unless he lists at least one alternate airport for each destination airport in...
14 CFR 121.621 - Alternate airport for destination: Flag operations.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Alternate airport for destination: Flag... § 121.621 Alternate airport for destination: Flag operations. (a) No person may dispatch an airplane under IFR or over-the-top unless he lists at least one alternate airport for each destination airport in...
14 CFR 121.621 - Alternate airport for destination: Flag operations.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Alternate airport for destination: Flag... § 121.621 Alternate airport for destination: Flag operations. (a) No person may dispatch an airplane under IFR or over-the-top unless he lists at least one alternate airport for each destination airport in...
2011-02-18
CAPE CANAVERAL, Fla. -- Members of the Brevard Police and Fire Pipes and Drums kick off the "The National 9/11 Flag" stitching ceremony in the Debus Conference Facility at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
2011-02-18
CAPE CANAVERAL, Fla. -- Chief of Fire Training George Hoggard with NASA Kennedy Space Center Protective Services contributes stitches to the "National 9/11 Flag" during a ceremony in the Debus Conference Facility at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
2011-02-18
CAPE CANAVERAL, Fla. -- Kelvin Manning, associate director for Business Operations at NASA's Kennedy Space Center, contributes stitches to the "National 9/11 Flag" during a ceremony in the Debus Conference Facility at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
2011-02-18
CAPE CANAVERAL, Fla. -- Joe Dowdy, special operations manager at NASA's Kennedy Space Center, contributes stitches to the "National 9/11 Flag" during a ceremony in the Debus Conference Facility at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
2011-02-18
CAPE CANAVERAL, Fla. -- Members of the Brevard Police and Fire Pipes and Drums kick off the "The National 9/11 Flag" stitching ceremony in the Debus Conference Facility at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
NASA Astrophysics Data System (ADS)
Pöppl, Ronald; Keesstra, Saskia; Maroulis, Jerry
2017-04-01
Human-induced landscape change is difficult to predict due to the complexity inherent in both geomorphic and social systems as well as due to emerging coupling relationships between them. To better understand system complexity and system response to change, connectivity has become an important research paradigm within various disciplines including geomorphology, hydrology and ecology. With the proposed conceptual connectivity framework on geomorphic change in human-impacted fluvial systems a cautionary note is flagged regarding the need (i) to include and to systematically conceptualise the role of different types of human agency in altering connectivity relationships in geomorphic systems and (ii) to integrate notions of human-environment interactions to connectivity concepts in geomorphology to better explain causes and trajectories of landscape change. Underpinned by case study examples, the presented conceptual framework is able to explain how geomorphic response of fluvial systems to human disturbance is determined by system-specific boundary conditions (incl. system history, related legacy effects and lag times), vegetation dynamics and human-induced functional relationships (i.e. feedback mechanisms) between the different spatial dimensions of connectivity. It is further demonstrated how changes in social systems can trigger a process-response feedback loop between social and geomorphic systems that further governs the trajectory of landscape change in coupled human-geomorphic systems.
Proteins that interact with calgranulin B in the human colon cancer cell line HCT-116.
Myung, Jae Kyung; Yeo, Seung-Gu; Kim, Kyung Hee; Baek, Kwang-Soo; Shin, Daye; Kim, Jong Heon; Cho, Jae Youl; Yoo, Byong Chul
2017-01-24
Calgranulin B is released from immune cells and can be internalized into colon cancer cells to prevent proliferation. The present study aimed to identify proteins that interact with calgranulin B to suppress the proliferation of colon cancer cells, and to obtain information on the underlying anti-tumor mechanism(s) of calgranulin B. Calgranulin B expression was induced in colon cancer cell line HCT-116 by infection with calgranulin B-FLAG expressing lentivirus, and it led to a significant suppression of cell proliferation. Proteins that interacted with calgranulin B were obtained by immunoprecipitation using whole homogenate of lentivirus-infected HCT-116 cells which expressing calgranulin B-FLAG, and identified using liquid chromatography-mass spectrometry/mass spectrometry analysis. A total of 454 proteins were identified that potentially interact with calgranulin B, and most identified proteins were associated with RNA processing, post-transcriptional modifications and the EIF2 signaling pathway. Direct interaction of calgranulin B with flotillin-1, dynein intermediate chain 1, and CD59 glycoprotein has been confirmed, and the molecules N-myc proto-oncogene protein, rapamycin-insensitive companion of mTOR, and myc proto-oncogene protein were shown to regulate calgranulin B-interacting proteins. Our results provide new insight and useful information to explain the possible mechanism(s) underlying the role of calgranulin B as an anti-tumor effector in colon cancer cells.
Hirai, Kumiko; Kuroyanagi, Hidehito; Tatebayashi, Yoshitaka; Hayashi, Yoshitaka; Hirabayashi-Takahashi, Kanako; Saito, Kuniaki; Haga, Seiich; Uemura, Tomihiko; Izumi, Susumu
2010-12-01
l-kynurenine 3-monooxygenase (KMO) is an NAD(P)H-dependent flavin monooxygenase that catalyses the hydroxylation of l-kynurenine to 3-hydroxykynurenine, and is localized as an oligomer in the mitochondrial outer membrane. In the human brain, KMO may play an important role in the formation of two neurotoxins, 3-hydroxykynurenine and quinolinic acid, both of which provoke severe neurodegenerative diseases. In mosquitos, it plays a role in the formation both of eye pigment and of an exflagellation-inducing factor (xanthurenic acid). Here, we present evidence that the C-terminal region of pig liver KMO plays a dual role. First, it is required for the enzymatic activity. Second, it functions as a mitochondrial targeting signal as seen in monoamine oxidase B (MAO B) or outer membrane cytochrome b(5). The first role was shown by the comparison of the enzymatic activity of two mutants (C-terminally FLAG-tagged KMO and carboxyl-terminal truncation form, KMOΔC50) with that of the wild-type enzyme expressed in COS-7 cells. The second role was demonstrated with fluorescence microscopy by the comparison of the intracellular localization of the wild-type, three carboxyl-terminal truncated forms (ΔC20, ΔC30 and ΔC50), C-terminally FLAG-tagged wild-type and a mutant KMO, where two arginine residues, Arg461-Arg462, were replaced with Ser residues.
Shendell, Derek G; Rawling, Mary-Michal; Foster, Christine; Bohlke, Alicia; Edwards, Bobbie; Rico, Susie A; Felix, Justina; Eaton, Sandra; Moen, Stephanie; Roberts, Eric M; Love, Mary Beth
2007-10-01
This paper describes a novel school-based, visual environmental public health educational intervention intended to help reduce the exposure of children-and adults-to outdoor air pollution, including known environmental asthma triggers like ozone and particles. The overarching goal was to enhance the learning, recreational, and work environments of students and staff. The specific purpose of the Asthma-Friendly Outdoor (Ambient) Air Quality Flag Program was to establish an education and communication tool for Central California communities that would accomplish two things: (1) Establish permanent local policy change to existing operating procedures in school districts and schools to help reduce the exposure of students, teachers, staff, and nearby communities to outdoor environmental asthma triggers and (2) provide education on air quality and potential health effects of exposure to air pollutants. Data on the program from its initial years are presented. To date, the following important lessons have been learned: (1) Science-based, simple, visual, low-cost school-based educational interventions to help reduce human exposure to outdoor environmental asthma triggers (i.e., ozone, particles, and pollens) can work in socioeconomically and ethnically diverse urban and rural or agricultural communities, and (2) local health and environmental justice groups such as asthma coalitions can successfully lead school-based environmental interventions to help improve children's quality of life.
2002-01-01
On platforms suspended from the top of the 525-foot-high VAB, workers use rollers and brushes to repaint the NASA logo on the southeast side of the Vehicle Assembly Building. Known as the "meatball," the logo measures 110 feet by 132 feet, or about 12,300 square feet. The U.S. flag is also being repainted. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary.
Identification of actin binding protein, ABP-280, as a binding partner of human Lnk adaptor protein.
He, X; Li, Y; Schembri-King, J; Jakes, S; Hayashi, J
2000-08-01
Human Lnk (hLnk) is an adaptor protein with multiple functional domains that regulates T cell activation signaling. In order to identify cellular Lnk binding partners, a yeast two-hybrid screening of human spleen cDNA library was carried out using human hLnk as bait. A polypeptide sequence identical to the C-terminal segment of the actin binding protein (ABP-280) was identified as a hLnk binding protein. The expressed hLnk and the FLAG tagged C-terminal 673 amino acid residues of ABP-280 or the endogenous ABP-280 in COS-7 cells could be co-immunoprecipitated using antibodies either to hLnk, FLAG or ABP-280, respectively. Furthermore, immunofluorescence confocal microscope showed that hLnk and ABP-280 co-localized at the plasma membrane and at juxtanuclear region of COS-7 cells. In Jurkat cells, the endogenous hLnk also associates with the endogenous ABP-280 indicating that the association of these two proteins is physiological. The interacting domains of both proteins were mapped using yeast two-hybrid assays. Our results indicate that hLnk binds to the residues 2006-2454 (repeats 19-23C) of ABP-280. The domain in hLnk that associates with ABP-280 was mapped to an interdomain region of 56 amino acids between pleckstrin homology and Src homology 2 domains. These results suggest that hLnk may exert its regulatory role through its association with ABP-280.
Release of Archives Helps Fill Gap in Files on Wartime Atrocities
ERIC Educational Resources Information Center
Byrne, Richard
2007-01-01
Whether it is the hunt for the last surviving perpetrators of the Holocaust, the restitution of looted artworks, or new evidence of the complicity of governments in that immense crime against humanity by Germany and its allies, U.S. public interest in European war crimes has not flagged since the end of World War II. But the war crimes committed…
In vivo over-expression of KGF mimic human middle ear cholesteatoma.
Yamamoto-Fukuda, Tomomi; Akiyama, Naotaro; Shibata, Yasuaki; Takahashi, Haruo; Ikeda, Tohru; Koji, Takehiko
2015-10-01
We reported previously that keratinocyte growth factor (KGF), a mesenchymal cell-derived paracrine growth factor, plays an important role in middle ear cholesteatoma formation, which is characterized by marked proliferation of epithelial cells. Here, we investigated whether KGF, the main factor that induces cholesteatoma, overexpression in vivo results in the formation of cholesteatoma. Flag-hKGF cDNA driven by CMV14 promoter was transfected through electroporation into the external auditory canal (EAC) of rats once (short-term model) or five times on every fourth day (long-term model). Ears transfected with empty vector were used as controls. Successful transfection of plasmids into epithelial and stromal cells was confirmed by Flag immunohistochemistry. In the short-term model, the intensity of KGF protein was the strongest in hKGF transfected ear at day 4. KGF expression induced epithelial cell proliferation, reaching a peak level at day 4 and then decreased later, while in the long-term model, KGF expression in the EAC led to middle ear cholesteatoma formation. In conclusion, we described here a new experimental model of human middle ear cholesteatoma, and demonstrated that KGF and KGF receptor paracrine action play an essential role in middle ear cholesteatoma formation in an in vivo model.
New quantitative trait loci in wheat for flag leaf resistance to Stagonospora nodorum blotch.
Francki, M G; Shankar, M; Walker, E; Loughman, R; Golzar, H; Ohm, H
2011-11-01
Stagonospora nodorum blotch (SNB) is a significant disease in some wheat-growing regions of the world. Resistance in wheat to Stagonospora nodorum is complex, whereby genes for seedling, flag leaf, and glume resistance are independent. The aims of this study were to identify alternative genes for flag leaf resistance, to compare and contrast with known quantitative trait loci (QTL) for SNB resistance, and to determine the potential role of host-specific toxins for SNB QTL. Novel QTL for flag leaf resistance were identified on chromosome 2AS inherited from winter wheat parent 'P92201D5' and chromosome 1BS from spring wheat parent 'EGA Blanco'. The chromosomal map position of markers associated with QTL on 1BS and 2AS indicated that they were unlikely to be associated with known host-toxin insensitivity loci. A QTL on chromosome 5BL inherited from EGA Blanco had highly significant association with markers fcp001 and fcp620 based on disease evaluation in 2007 and, therefore, is likely to be associated with Tsn1-ToxA insensitivity for flag leaf resistance. However, fcp001 and fcp620 were not associated with a QTL detected based on disease evaluation in 2008, indicating two linked QTL for flag leaf resistance with multiple genes residing on 5BL. This study identified novel QTL and their effects in controlling flag leaf SNB resistance.
3 CFR 8535 - Proclamation 8535 of June 11, 2010. Flag Day and National Flag Week, 2010
Code of Federal Regulations, 2011 CFR
2011-01-01
..., the thirteen stripes alternating red and white, and thirteen white stars in a blue field, represented... luminosity, and the enduring American story that it represents. Although the configuration of stars and... first embraced by our Founders, the Stars and Stripes remain the symbol of our Nation’s pride. On Flag...
22 CFR 201.15 - U.S. flag vessel shipping requirements.
Code of Federal Regulations, 2011 CFR
2011-04-01
... and tankers shall be achieved for each quantitative unit of cargo. A quantitative unit of cargo is the... determined that at least 50% of the quantitative unit will move on U.S. flag vessels, to the extent that such... used for achieving compliance for the quantitative unit. (c) Nonavailability of U.S. flag vessels. Upon...
22 CFR 201.15 - U.S. flag vessel shipping requirements.
Code of Federal Regulations, 2014 CFR
2014-04-01
... and tankers shall be achieved for each quantitative unit of cargo. A quantitative unit of cargo is the... determined that at least 50% of the quantitative unit will move on U.S. flag vessels, to the extent that such... used for achieving compliance for the quantitative unit. (c) Nonavailability of U.S. flag vessels. Upon...
22 CFR 201.15 - U.S. flag vessel shipping requirements.
Code of Federal Regulations, 2010 CFR
2010-04-01
... and tankers shall be achieved for each quantitative unit of cargo. A quantitative unit of cargo is the... determined that at least 50% of the quantitative unit will move on U.S. flag vessels, to the extent that such... used for achieving compliance for the quantitative unit. (c) Nonavailability of U.S. flag vessels. Upon...
22 CFR 201.15 - U.S. flag vessel shipping requirements.
Code of Federal Regulations, 2012 CFR
2012-04-01
... and tankers shall be achieved for each quantitative unit of cargo. A quantitative unit of cargo is the... determined that at least 50% of the quantitative unit will move on U.S. flag vessels, to the extent that such... used for achieving compliance for the quantitative unit. (c) Nonavailability of U.S. flag vessels. Upon...
22 CFR 201.15 - U.S. flag vessel shipping requirements.
Code of Federal Regulations, 2013 CFR
2013-04-01
... and tankers shall be achieved for each quantitative unit of cargo. A quantitative unit of cargo is the... determined that at least 50% of the quantitative unit will move on U.S. flag vessels, to the extent that such... used for achieving compliance for the quantitative unit. (c) Nonavailability of U.S. flag vessels. Upon...
Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-12
... yield Flag K would increase intermarket competition because it offers customers an alternative means to...) Increase the fee for orders yielding Flag K, which routes to NASDAQ OMX PSX (``PSX'') using ROUC or ROUE... for orders yielding Flag K, which routes to PSX using ROUC or ROUE routing strategies; and (ii...
FIRE! A Red Flag Tap in Reclaiming Intervention
ERIC Educational Resources Information Center
Bodnar, Brian
2007-01-01
"Red Flag Interventions" address problems which are imported from elsewhere and acted out towards persons who are in effect innocent bystanders. This is commonly seen as students "carry in" problems from the home or street to school, or they "carry over" conflicts from one class to the next. A third variation of Red Flag intervention is when a…
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-19
... Exchange introduced new Flags ZA (Retail Order, adds liquidity) and ZR (Retail Order, removes liquidity... will enable Members, and in turn, their retail customers, to benefit from the enhanced rebate (Flag ZA... able to benefit from the rebate (Flag ZA) for utilizing Retail Orders without regards to whether the...
Red flags: a case series of clinician-family communication challenges in the context of CHD.
Sekar, Priya; Marcus, Katie L; Williams, Erin P; Boss, Renee D
2017-07-01
We describe three cases of newborns with complex CHD characterised by communication challenges. These communication challenges were categorised as patient, family, or system-related red flags. Strategies for addressing these red flags were proposed, for the goal of optimising care and improving quality of life in this vulnerable population.
75 FR 61836 - Additional Designation of Individuals and Entities Pursuant to Executive Order 13382
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-06
.... ABTIN 1 Container Ship 13,760DWT 9,957GRT IRAN flag (IRISL); Vessel Registration Identification IMO... IMO 9405954 (Malta) (vessel) [NPWMD]. 8. EIGHTH OCEAN General Cargo 22,882DWT 15,670GRT GERMANY flag... Container Ship 85,896DWT 74,175GRT MALTA flag (IRISL); Vessel Registration Identification IMO 9349576 (Malta...
3 CFR 8837 - Proclamation 8837 of June 11, 2012. Flag Day and National Flag Week, 2012
Code of Federal Regulations, 2013 CFR
2013-01-01
... homes and storefronts. Generations of service members have raised our country's colors over military... America A Proclamation Ninety-six years ago, our Nation first came together to celebrate Flag Day—an occasion when President Woodrow Wilson asked us to “stand with united hearts for an America which no man...
VLA Hosts "Flag Across America"
NASA Astrophysics Data System (ADS)
2001-11-01
The National Radio Astronomy Observatory (NRAO) hosted the runners and support personnel of the "Americans United Flag Across America" run as the transcontinental memorial and fundraising effort came through New Mexico. The flag run arrived at NRAO's Very Large Array (VLA) radio telescope west of Socorro, NM, early in the post-Midnight morning of Monday, November 5, and departed after sunrise that morning en route to the Arizona border. Drivers, runners and support personnel stayed overnight at the VLA. During the night, a "VLA Night Owl Run" kept the flag moving around the VLA area until the westward trek resumed after dawn. The run began Oct. 11, one month after the terrorist attacks on New York and Washington. Organized by employees of American and United Airlines to honor the flight crews lost in those attacks, to show support for U.S. troops and to raise funds to help the victims' families, the run will take an American flag from Boston Logan Airport to Los Angeles International Airport. The Boston-to-Los Angeles trip represents the intended journey of American Flight 11 and United Flight 175, both of which were crashed by terrorists into the World Trade Center. "Our observatory was proud to host this group and honored that they brought this flag through our facility," said Miller Goss, NRAO's director of VLA operations. The runners carried a flag that flew in a U.S. F-16 over Iraq in support of Operation Southern Watch on Oct. 2, and has visited Ground Zero in Manhattan. The flag is scheduled to arrive in Los Angeles on Veterans Day, Nov. 11. The National Radio Astronomy Observatory is a facility of the National Science Foundation, operated under cooperative agreement by Associated Universities, Inc.
Association between community socioeconomic characteristics and access to youth flag football.
Kroshus, Emily; Sonnen, Aly J; Chrisman, Sara Pd; Rivara, Frederick P
2018-01-12
The American Academy of Pediatrics has recommended that opportunities for non-tackling American football (e.g., flag football) be expanded, given concerns about the risks of brain trauma from tackle football. This study tested the hypothesis that flag football would be more accessible in communities characterised by higher socioeconomic status residents. In July 2017, the locations of community-based organisations offering youth flag and tackle football for youth between the ages of 6 and 13 in two US states (Georgia and Washington) were aggregated (n=440). Organisations were coded in terms of the availability of tackle and/or flag football teams for youth at each year of age between 6 and 13. Multivariate logistic regression analyses were used to assess the odds of a community-based football organisation offering flag football, by community socioeconomic and demographic characteristics. In both states, communities with more educated residents were more likely to offer flag football for youth aged 6-12. For example, among 6 year-olds every 10% increase in the number of adult residents with a college education was associated with 1.51 times the odds of flag football availability (95% CI 1.22 to 1.86, P<0.001). These results suggest that youth living in communities characterised by low educational attainment are less likely than other youth to have the option of a lower contact alternative to tackle football. Relying on voluntary community-level adoption of lower contact alternatives to tackle football may result in inequitable access to such sport options. This may contribute to an inequitable burden of brain trauma from youth sport. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
The American flag on the VAB is being repainted
NASA Technical Reports Server (NTRS)
1998-01-01
Painters are suspended on platforms from the top of the 525-foot- high Vehicle Assembly Building (VAB) at KSC during repainting of the American flag. The flag spans an area 209 feet by 110 feet and will require 510 gallons of red, white and blue paint. Each stripe of the flag is 9 feet wide and each star is 6 feet in diameter. The platforms are operated by two electric motors and travel 35 feet per minute. Work is being done with rollers, with brushes being used for details. The paint was donated by ICI Devoe of Louisville, Ky. In addition to the flag, the Bicentennial Emblem on the other side of the VAB doors is being replaced by the NASA logo, honoring NASA's 40th anniversary (in October). The logo covers an area 110 feet by 132 feet. Work is expected to be completed in mid-September.
2011-02-18
CAPE CANAVERAL, Fla. -- Members of the United States Air Force 45th Space Wing Honor Guard and more than a dozen 9/11 first responders take part in "The National 9/11 Flag" stitching ceremony in the Debus Conference Facility at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
2011-02-18
CAPE CANAVERAL, Fla. – Deputy Fire Chief Rick Anderson, left, Chief of Fire Training George Hoggard, and Assistant Chief of Fire Training David Seymour with NASA Kennedy Space Center Protective Services participated in the "National 9/11 Flag" stitching ceremony in the Debus Conference Facility at the Kennedy Space Center Visitor Complex in Florida. The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
2011-02-18
CAPE CANAVERAL, Fla. -- In the Debus Conference Facility at the Kennedy Space Center Visitor Complex in Florida, Jeff Parness, the director, founder and chairman of the "New York Says Thank You Foundation" talks about the work and devotion that has gone into restoring "The National 9/11 Flag." The contributions of NASA, Kennedy Space Center and the state of Florida were stitched into the fabric of the American Flag, which was recovered near ground zero following the World Trade Center attacks on Sept. 11, 2001. The "New York Says Thank You Foundation" is taking the flag on a cross-country journey to be restored to its original 13-stripe design using pieces of fabric from American flags destined for retirement in all 50 states. Once the flag is restored, it will become a permanent collection of the National September 11 Memorial Museum being built at the World Trade Center site. Photo credit: NASA/Kim Shiflett
STS-44 Atlantis, Orbiter Vehicle (OV) 104, crew insignia
1999-09-15
STS044-S-001 (July 1991) --- Designed by the participating crew members, the STS-44 patch shows the space shuttle Atlantis shortly after liftoff as it rolls to ascend into orbit. The orbital path illustrated by the red, white and blue of the stylized American flag represents the American contribution and strength derived from this mission. The black background of space, indicative of the mysteries of the universe, is illuminated by six large stars, which depict the American crew of six and the hopes that travel with them. The smaller stars represent the myriad of unheralded Americans who work in support of this mission. Within the shuttle's payload bay is a Defense Support Program (DSP) Satellite which will help insure peace. The stars of the flag symbolize our leadership in an exciting quest of space and the boundless dreams for mankind's future. In the words of a crew spokesman, "the stars of the flag symbolize our leadership in an exciting quest of space and the boundless dreams for humanity's future." The NASA insignia design for space shuttle flights is reserved for use by the astronauts and for other official use as the NASA Administrator may authorize. Public availability has been approved only in the forms of illustrations by the various news media. When and if there is any change in this policy, which is not anticipated, the change will be publicly announced. Photo credit: NASA
Maritime labor-management affiliation guide 2000
DOT National Transportation Integrated Search
2000-01-01
This guide presents brief descriptions of major maritime management and trade organizations, seafaring labor organizations and their affiliations. Also included are U.S.-flag ship owner/operator companies, and their union affiliations. A directory of...
Telecommunications end-to-end systems monitoring on TOPEX/Poseidon: Tools and techniques
NASA Technical Reports Server (NTRS)
Calanche, Bruno J.
1994-01-01
The TOPEX/Poseidon Project Satellite Performance Analysis Team's (SPAT) roles and responsibilities have grown to include functions that are typically performed by other teams on JPL Flight Projects. In particular, SPAT Telecommunication's role has expanded beyond the nominal function of monitoring, assessing, characterizing, and trending the spacecraft (S/C) RF/Telecom subsystem to one of End-to-End Information Systems (EEIS) monitoring. This has been accomplished by taking advantage of the spacecraft and ground data system structures and protocols. By processing both the received spacecraft telemetry minor frame ground generated CRC flags and NASCOM block poly error flags, bit error rates (BER) for each link segment can be determined. This provides the capability to characterize the separate link segments, determine science data recovery, and perform fault/anomaly detection and isolation. By monitoring and managing the links, TOPEX has successfully recovered approximately 99.9 percent of the science data with an integrity (BER) of better than 1 x 10(exp 8). This paper presents the algorithms used to process the above flags and the techniques used for EEIS monitoring.
Children's Interpretation of Focus Expressions in English and Mandarin
ERIC Educational Resources Information Center
Notley, Anna; Zhou, Peng; Crain, Stephen; Thornton, Rosalind
2009-01-01
Children often produce nonadult responses to sentences with the focus operator only, such as "Only the cat is holding a flag." For example, children often accept this sentence as a description of a situation in which a cat holds a flag and a duck holds both a flag and a balloon. One proposed analysis, by Paterson, Liversedge, Rowland & Filik…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-17
... ``added liquidity'' to ``removed liquidity'' ratio of at least 70% where added flags are defined as B, HA..., Flag N is yielded when an order removes liquidity from the EDGX book in Tapes B or C securities. In... Members, the Exchange proposes to amend Flag N so that it only applies to orders that remove liquidity...
Know Your America: Suggested Study Course in Americanism. Revised Edition.
ERIC Educational Resources Information Center
American Legion, Indianapolis, IN. Americanism and Children's Youth Div.
The purpose of this booklet is to increase understanding of fundamental U.S. documents, the U.S. flag, patriotic institutions, and of San Francisco (California), March 14-16, 1986 of U.S. residents. Unit 2 describes and interprets the code of displaying the U.S. flag and provides a suggested flag education unit of study. Units 3 and 4 offer…
A Retrospective Estimate of Ear Disease Detection Using the "Red Flags" in a Clinical Sample.
Klyn, Niall A M; Kleindienst Robler, Samantha; Alfakir, Razan; Nielsen, Donald W; Griffith, James W; Carlson, Deborah L; Lundy, Larry; Dhar, Sumitrajit; Zapala, David A
2018-03-01
The purpose of this study was to evaluate the specificity and sensitivity of two red flag protocols in detecting ear diseases associated with changes in hearing. The presence of red-flag symptoms was determined in a chart review of 307 adult patients from the Mayo Clinic Florida Departments of Otorhinolaryngology and Audiology. Participants formed a convenience sample recruited for a separate study. Neurotologist diagnosis was the criterion for comparisons. Of the 251 patient files retained for analysis, 191 had one or more targeted diseases and 60 had age- or noise-related hearing loss. Food and Drug Administration red flags sensitivity was 91% (confidence interval [CI], 86 to 95%) and specificity was 72% (CI, 59 to 83%). American Academy of Otolaryngology-Head and Neck Surgery red flags sensitivity was 98% (CI, 95 to 99%) and specificity was 20% (CI, 11 to 32%). Stakeholders must determine which diseases are meaningful contraindications for hearing aid use and whether these red-flag protocols have acceptable levels of sensitivity and specificity. As direct-to-consumer models of hearing devices increase, a disease detection method that does not require provider intercession would be useful.
Red flags in children with chronic abdominal pain and Crohn's disease-a single center experience.
El-Chammas, Khalil; Majeskie, Angela; Simpson, Pippa; Sood, Manu; Miranda, Adrian
2013-04-01
To compare history and symptoms at initial presentation of patients with chronic abdominal pain (CAP) and Crohn's disease (CD). Red flags are used to help determine which patients with CAP are likely to have an underlying disease such as CD. However, red flags have not been validated and pediatric studies are lacking. Patients seen in the outpatient Pediatric Gastroenterology Clinic at Children's Hospital of Wisconsin between 2005 and 2008 prospectively completed a demographic, history, and symptom questionnaire. Patients with abdominal pain for at least 1 month and no evidence of organic disease were compared with patients diagnosed with CD confirmed by mucosal biopsies. Data were collected on 606 patients (128 with CD and 478 with functional gastrointestinal disorders). Patients with functional gastrointestinal disorders had more stressors (P < .001), were more likely to have a positive family history of irritable bowel syndrome, reflux, or constipation (P < .05), were more likely to have vomiting but less likely to have hematochezia, weight loss, and problems gaining weight (P < .05); wake from sleep and joint pain were no different between groups. Anemia, hematochezia, and weight loss were most predictive of CD (cumulative sensitivity of 94%). The presence of anemia, hematochezia, and weight loss help identify patients with CAP who require further work-up and referral to a pediatric gastroenterologist. Furthermore, waking from sleep or joint pain occurred similarly between groups and should not be considered as "red flags." Copyright © 2013. Published by Mosby, Inc.
Human Mammary Epithelial Cell Transformation by Rho GTPase Through a Novel Mechanism
2009-08-01
cells were transfected with myc-tagged Prks -ROCK1 or Prks -ROCK2, flag-tagged Prc-PKN-AL, or mDia1 using calcium phosphate method. The transfectants...plasmids, Prks -ROCK1, Prks -ROCK2, Prc-PKN-AL, and pFL-mDia1, were transfected into 293T cells, and cell lysates were incubated with GTP-g-S–loaded GST
2009-12-01
other services for early UNIX systems at Bell labs. In many UNIX based systems, the field added to ‘etc/ passwd ’ file to carry GCOS ID information was...charset, and external. struct options_main { /* Option flags */ opt_flags flags; /* Password files */ struct list_main * passwd ; /* Password file...object PASSWD . It is part of several other data structures. struct PASSWD { int id; char *login; char *passwd_hash; int UID
View of special 'gift bag' of exchange items to be carried during ASTP
NASA Technical Reports Server (NTRS)
1975-01-01
A close-up view of the special 'gift bag' in which several exchange/gift items will be carried aboard the Apollo Command Module during the joint U.S.-U.S.S.R. Apollo Soyuz Test Project (ASTP) mission. Some of these items are seen here alongside the bag. They are the sectionized ASTP Commemorative Plaque, ten 8X12 inch American flags, 8.07X16.14 inch (205mm x 410mm) Soviet Union flag, a special box of white spruce tree seeds, and the ASTP Certification to authorize the ASTP docking. The gifts will be presented and the exchange made while the Apollo and Soyuz spacecraft are docked in Earth orbit.
2007-04-19
KENNEDY SPACE CENTER, FLA. -- The finishing touches are painted on the American flag that embellishes the southwest side of the Vehicle Assembly Building at NASA's Kennedy Space Center. The flag and the NASA logo, which is on the southeast side, have both been refreshed with new paint. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, which is known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. The building stands 525-feet tall. Photo credit: NASA/George Shelton
An Auto-flag Method of Radio Visibility Data Based on Support Vector Machine
NASA Astrophysics Data System (ADS)
Dai, Hui-mei; Mei, Ying; Wang, Wei; Deng, Hui; Wang, Feng
2017-01-01
The Mingantu Ultrawide Spectral Radioheliograph (MUSER) has entered a test observation stage. After the construction of the data acquisition and storage system, it is urgent to automatically flag and eliminate the abnormal visibility data so as to improve the imaging quality. In this paper, according to the observational records, we create a credible visibility set, and further obtain the corresponding flag model of visibility data by using the support vector machine (SVM) technique. The results show that the SVM is a robust approach to flag the MUSER visibility data, and can attain an accuracy of about 86%. Meanwhile, this method will not be affected by solar activities, such as flare eruptions.
Federal Register 2010, 2011, 2012, 2013, 2014
2013-01-07
... the HP-API order entry protocol (HP-API) in order to qualify for the rates on Flags ZA and ZR. The... via FIX in order to qualify for the rates on Flags ZA (rebate of $0.0032 per share) and ZR (fee of $0... qualify for the rates on Flags ZA and ZR. The attestation requirement, as described above and in SR-EDGX...
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-11
..., MM, RP, 3, or 4 and removal flags are defined as Flags BB, MT, N, W, PI, PR, or 6. Where a Member..., BB and PI where they satisfy the volume tier requirements for the Mega Tier in Footnote 1. Currently... removing liquidity and the rate for Flags N, W, 6, BB, and PI subject to the volume thresholds in Footnotes...
Zhang, Guang Lan; Keskin, Derin B.; Lin, Hsin-Nan; Lin, Hong Huang; DeLuca, David S.; Leppanen, Scott; Milford, Edgar L.; Reinherz, Ellis L.; Brusic, Vladimir
2014-01-01
Human leukocyte antigens (HLA) are important biomarkers because multiple diseases, drug toxicity, and vaccine responses reveal strong HLA associations. Current clinical HLA typing is an elimination process requiring serial testing. We present an alternative in situ synthesized DNA-based microarray method that contains hundreds of thousands of probes representing a complete overlapping set covering 1,610 clinically relevant HLA class I alleles accompanied by computational tools for assigning HLA type to 4-digit resolution. Our proof-of-concept experiment included 21 blood samples, 18 cell lines, and multiple controls. The method is accurate, robust, and amenable to automation. Typing errors were restricted to homozygous samples or those with very closely related alleles from the same locus, but readily resolved by targeted DNA sequencing validation of flagged samples. High-throughput HLA typing technologies that are effective, yet inexpensive, can be used to analyze the world’s populations, benefiting both global public health and personalized health care. PMID:25505899
Sangawa, Takeshi; Tabata, Sanae; Suzuki, Kei; Saheki, Yasushi; Tanaka, Keiji; Takagi, Junichi
2013-01-01
Expression and purification of aggregation-prone and disulfide-containing proteins in Escherichia coli remains as a major hurdle for structural and functional analyses of high-value target proteins. Here, we present a novel gene-fusion strategy that greatly simplifies purification and refolding procedure at very low cost using a unique hyperacidic module derived from the human amyloid precursor protein. Fusion with this polypeptide (dubbed FATT for Flag-Acidic-Target Tag) results in near-complete soluble expression of variety of extracellular proteins, which can be directly refolded in the crude bacterial lysate and purified in one-step by anion exchange chromatography. Application of this system enabled preparation of functionally active extracellular enzymes and antibody fragments without the need for condition optimization. PMID:23526492
Robotic Mining Competition - Opening Ceremony
2018-05-15
A flag presentation and singing of the National Anthem are part of the opening ceremony of NASA's 9th Robotic Mining Competition, May 15, in the RobotPits in the Educator Resource Center at Kennedy Space Center Visitor Complex in Florida. More than 40 student teams from colleges and universities around the U.S. will use their uniquely designed mining robots to dig in a supersized sandbox filled with BP-1, or simulated Martian soil, gravel and rocks, and participate in other competition requirements. The Robotic Mining Competition is a NASA Human Exploration and Operations Mission Directorate project designed to encourage students in science, technology, engineering and math, or STEM fields. The project provides a competitive environment to foster innovative ideas and solutions that could be used on NASA's deep space missions.
Deeb, Asma; Elfatih, Abubaker
2018-03-01
Hypophosphatasia (HPP) is an inborn error of metabolism with significant morbidity and mortality. Its presentation is nonspecific leading to delayed or missed diagnosis. Low alkaline phosphatase (ALP) is a diagnostic test. Unlike high ALP, low level is commonly not flagged by laboratories as abnormal. A new treatment was shown to be effective in HPP. In this study we aimed to establish the frequency of low ALP levels requiring notification to physicians by the laboratory and also to describe the clinical manifestations of patients presenting with low ALP for a possible diagnosis of HPP. Patients under age 18 years with low ALP levels were identified from biochemistry records over a period of 6 months. Reference ranges were used as per the Associated Regional and University Pathologists Reference Laboratory (Utah, USA). Electronic results for patients with low levels were checked for flagging as abnormal/low ALP results. Charts of identified patients were reviewed. Presenting features were categorized under groups of disorders. ALP levels were tested in 2890 patients. 702 had values less than 160 U/L. Of these patients, 226 (32%) had age/gender specific low ALP. None of the low ALP results was flagged as low. Twenty-one had more than one low reading and their charts were reviewed. Four patients in the neuromuscular and four in the miscellaneous group presented with features consistent with HPP despite these patients having no specific diagnoses. Laboratories do not alert physicians in cases with low ALP levels. A persistently low level in patients with unspecified diagnoses could be a key to diagnose HPP. Implementing lab-specific ranges and alerting for low levels could prompt physicians to investigate for undiagnosed HPP.
VizieR Online Data Catalog: COSMOS Multi-Wavelength Photometry Catalog (Capak+, 2007)
NASA Astrophysics Data System (ADS)
Capak, P.; Aussel, H.; Ajiki, M.; McCracken, H. J.; Mobasher, B.; Scoville, N.; Shopbell, P.; Taniguchi, Y.; Thompson, D.; Tribiano, S.; Sasaki, S.; Blain, A. W.; Brusa, M.; Carilli, C.; Comastri, A.; Carollo, C. M.; Cassata, P.; Colbert, J.; Ellis, R. S.; Elvis, M.; Giavalisco, M.; Green, W.; Guzzo, L.; Hasinger, G.; Ilbert, O.; Impey, C.; Jahnke, K.; Kartaltepe, J.; Kneib, J.-P.; Koda, J.; Koekemoer, A.; Komiyama, Y.; Leauthaud, A.; Lefevre, O.; Lilly, S.; Liu, C.; Massey, R.; Miyazaki, S.; Murayama, T.; Nagao, T.; Peacock, J. A.; Pickles, A.; Porciani, C.; Renzini, A.; Rhodes, J.; Rich, M.; Salvato, M.; Sanders, D. B.; Scarlata, C.; Schiminovich, D.; Schinnerer, E.; Scodeggio, M.; Sheth, K.; Shioya, Y.; Tasca, L. A. M.; Taylor, J. E.; Yan, L.; Zamorani, G.
2008-03-01
The present COSMOS data were collected on a variety of telescopes and instruments, as well as from the Sloan Digital Sky Survey (SDSS) second data release (DR2) archive (u, g, r, i, z) and Hubble Space Telescope (HST, F814W). This paper covers the processing of the data obtained with Suprime-Cam on the Subaru 8.3m telescope (Bj, Vj, g+, r+, i+, z+, NB816), Megaprime on the 3.6m Canada-France-Hawaii Telescope (CFHT, u*, i*), FLAMINGOS on the Kitt Peak National Observatory (KPNO, Ks) 4m telescope, and the Infrared Side Port Imager on the Cerro Tololo Inter-American Observatory (CTIO, Ks) 4m telescope during the 2004-2005 observing season. The COSMOS I band catalog is an I band selected multi-color catalog for 2 square degrees centered on the COSMOS field at 10:00:28.6, +02:12:21. The total magnitude (SExtractor mag_auto) for a source must have an AB magnitude of less than i+<25 to appear in the archival catalog. All photometry is in the AB magnitude system and measured in a 3 arc second aperture on PSF-matched images unless otherwise noted. A magnitude of -99 indicates a photometric measurement was not possible due to lack of data, a large number of bad pixels, or saturation. A magnitude of 99.0 indicates no detection. In the case of no detection the error given for the object is the 1 sigma limiting magnitude at the position of the souce. The photometry is as measured on the images with no corrections applied. We recommend applying the magnitude offsets in the paper to obtain the best possible photometry. More details on the photometry are available in the paper. The Photometric Redshifts included in this catalog are described in Mobasher et al. (2007ApJS..172..117M) and have an accuracy of dz/(1+z)<0.031 at z<1.2 and I<24. It is important to pay attention to the flag columns at the end of the catalog. The cleanest catalog will have all flags set to 0. The photometry flags indicate the area of the photometry aperture, in square arc seconds, which is in a masked region. A flag of 1 indicates 14 percent of the aperture is masked, so any flagged object should be carefully checked. Objects with a de-blending flag set to 1 are potentially spurious and should not be used for statistical studies. However, the photometry for real sources with a de-blending flag set to 1 is good if they fall outside of masked region. (1 data file).
VizieR Online Data Catalog: COSMOS Multi-Wavelength Photometry Catalog (Capak+, 2007)
NASA Astrophysics Data System (ADS)
Capak, P.; Aussel, H.; Ajiki, M.; McCracken, H. J.; Mobasher, B.; Scoville, N.; Shopbell, P.; Taniguchi, Y.; Thompson, D.; Tribiano, S.; Sasaki, S.; Blain, A. W.; Brusa, M.; Carilli, C.; Comastri, A.; Carollo, C. M.; Cassata, P.; Colbert, J.; Ellis, R. S.; Elvis, M.; Giavalisco, M.; Green, W.; Guzzo, L.; Hasinger, G.; Ilbert, O.; Impey, C.; Jahnke, K.; Kartaltepe, J.; Kneib, J.-P.; Koda, J.; Koekemoer, A.; Komiyama, Y.; Leauthaud, A.; Lefevre, O.; Lilly, S.; Liu, C.; Massey, R.; Miyazaki, S.; Murayama, T.; Nagao, T.; Peacock, J. A.; Pickles, A.; Porciani, C.; Renzini, A.; Rhodes, J.; Rich, M.; Salvato, M.; Sanders, D. B.; Scarlata, C.; Schiminovich, D.; Schinnerer, E.; Scodeggio, M.; Sheth, K.; Shioya, Y.; Tasca, L. A. M.; Taylor, J. E.; Yan, L.; Zamorani, G.
2008-03-01
The present COSMOS data were collected on a variety of telescopes and instruments, as well as from the Sloan Digital Sky Survey (SDSS) second data release (DR2) archive (u, g, r, i, z) and Hubble Space Telescope (HST, F814W). This paper covers the processing of the data obtained with Suprime-Cam on the Subaru 8.3m telescope (Bj, Vj, g+, r+, i+, z+, NB816), Megaprime on the 3.6m Canada-France-Hawaii Telescope (CFHT, u*, i*), FLAMINGOS on the Kitt Peak National Observatory (KPNO, Ks) 4m telescope, and the Infrared Side Port Imager on the Cerro Tololo Inter-American Observatory (CTIO, Ks) 4m telescope during the 2004-2005 observing season. The COSMOS I band catalog is an I band selected multi-color catalog for 2 square degrees centered on the COSMOS field at 10:00:28.6, +02:12:21. The total magnitude (SExtractor mag_auto) for a source must have an AB magnitude of less than i+<25 to appear in the archival catalog. All photometry is in the AB magnitude system and measured in a 3" aperture on PSF-matched images unless otherwise noted. A magnitude of -99 indicates a photometric measurement was not possible due to lack of data, a large number of bad pixels, or saturation. A magnitude of 99.0 indicates no detection. In the case of no detection the error given for the object is the 1 sigma limiting magnitude at the position of the source. The photometry is as measured on the images with no corrections applied. We recommend applying the magnitude offsets in the paper to obtain the best possible photometry. More details on the photometry are available in the paper. The Photometric Redshifts included in this catalog are described in Mobasher et al. (2007ApJS..172..117M) and have an accuracy of dz/(1+z)<0.031 at z<1.2 and I<24. It is important to pay attention to the flag columns at the end of the catalog. The cleanest catalog will have all flags set to 0. The photometry flags indicate the area of the photometry aperture, in square arc seconds, which is in a masked region. A flag of 1 indicates 14 percent of the aperture is masked, so any flagged object should be carefully checked. Objects with a de-blending flag set to 1 are potentially spurious and should not be used for statistical studies. However, the photometry for real sources with a de-blending flag set to 1 is good if they fall outside of masked region. (1 data file).
Degue, Sarah; Dilillo, David
2009-06-01
Cross-reporting legislation, which permits child and animal welfare investigators to refer families with substantiated child maltreatment or animal cruelty for investigation by parallel agencies, has recently been adopted in several U.S. jurisdictions. The current study sheds light on the underlying assumption of these policies-that animal cruelty and family violence commonly co-occur. Exposure to family violence and animal cruelty is retrospectively assessed using a sample of 860 college students. Results suggest that animal abuse may be a red flag indicative of family violence in the home. Specifically, about 60% of participants who have witnessed or perpetrated animal cruelty as a child also report experiences with child maltreatment or domestic violence. Differential patterns of association were revealed between childhood victimization experiences and the type of animal cruelty exposure reported. This study extends current knowledge of the links between animal- and human-directed violence and provides initial support for the premise of cross-reporting legislation.
Construction of a functional silk-based biomaterial complex with immortalized chondrocytes in vivo.
Ni, Yusu; Jiang, Yi; Wen, Jianchuan; Shao, Zhenzhong; Chen, Xin; Sun, Shan; Yu, Huiqian; Li, Wen
2014-04-01
To explore the feasibility of constructing a functional biomaterial complex with regenerated silk fibroin membrane and immortalized chondrocytes in vivo. Rat auricular chondrocytes (RACs) were transfected with the lentivirus vector pGC-FU-hTERT-3FLAG or pGC-FU-GFP-3FLAG, encoding the human telomerase reverse transcriptase (hTERT) or GFP gene. The effects of regenerated silk fibroin film on the adhesion, growth of immortalized chondrocytes and expression of collagen II in vitro were analyzed with immunofluorescent histochemistry. Immortalized RACs were transformed. Induction by nutrient medium promoted higher expression levels of collagen II in transformed chondrocytes. The regenerated silk fibroin film was not cytotoxic to immortalized chondrocytes and had no adverse influence on their adhesion. Collagen II expression was good in the immortalized chondrocytes in vivo. The construction of a silk-based biomaterial complex with immortalized chondrocytes may provide a feasible kind of functional biomaterial for the repair of cartilage defects in clinical applications. Copyright © 2013 Wiley Periodicals, Inc.
Borgoiakov, V Iu; Fomenko, N V; Panov, V V; Chikova, E D
2010-01-01
In our study, Borrelia were revealed in the taiga ticks Ixodes persulcatus collected on vegetation by flagging, as well as in the ticks removed from the people who asked for help in the vaccination center located in the Novosibirsk Scientific Center of the Siberian Branch of Russian Academy of Science (NS SB RAS). By the isolation of Borrelia on BSK-H medum, the occurrence of B. garinii, B. afzelii, and B. miyamotoi was established in the territory of NSC. B. miyamotoi isolates were unstable and lost their ability to growth in later passages. DNA of the same three species of Borrelia was detected by PCR in the samples of ticks, both collected on vegetation by flagging and removed from humans. DNA of B. garinii was recorded most often; DNA of B. afzelii was less frequent; and the least number of positive samples was shown for B. miyamotoi. In the ticks collected on vegetation by flagging, DNA of B. garinii was found in 38.6%, B. afzelii in 9.9%, and B. miyamoboi in 3.9% of samples. In the ticks removed from people, number of positive samples was lesser; so, DNA of B. garinii was detected in 24.2%, B. afzelii in 6.9%, and B. miyamotoi in 5.6% of samples. Mixed infection with two Borrelia species was recorded, and DNA of B. mivamnotoi more often detected simultaneously with DNA of B. garinii.
Two Procedures to Flag Radio Frequency Interference in the UV Plane
NASA Astrophysics Data System (ADS)
Sekhar, Srikrishna; Athreya, Ramana
2018-07-01
We present two algorithms to identify and flag radio frequency interference (RFI) in radio interferometric imaging data. The first algorithm utilizes the redundancy of visibilities inside a UV cell in the visibility plane to identify corrupted data, while varying the detection threshold in accordance with the observed reduction in noise with radial UV distance. In the second algorithm, we propose a scheme to detect faint RFI in the visibility time-channel (TC) plane of baselines. The efficacy of identifying RFI in the residual visibilities is reduced by the presence of ripples due to inaccurate subtraction of the strongest sources. This can be due to several reasons including primary beam asymmetries and other direction-dependent calibration errors. We eliminated these ripples by clipping the corresponding peaks in the associated Fourier plane. RFI was detected in the ripple-free TC plane but was flagged in the original visibilities. Application of these two algorithms to five different 150 MHz data sets from the GMRT resulted in a reduction in image noise of 20%–50% throughout the field along with a reduction in systematics and a corresponding increase in the number of detected sources. However, in comparing the mean flux densities before and after flagging RFI, we find a differential change with the fainter sources (25σ < S < 100 mJy) showing a change of ‑6% to +1% relative to the stronger sources (S > 100 mJy). We are unable to explain this effect, but it could be related to the CLEAN bias known for interferometers.
Effect of flagellates on free-living bacterial abundance in an organically contaminated aquifer
Kinner, N.E.; Harvey, R.W.; Kazmierkiewicz-Tabaka, M.
1997-01-01
Little is known about the role of protists in the saturated subsurface. Porous media microcosms containing bacteria and protists, were used to determine whether flagellates from an organically contaminated aquifer could substantively affect the number of free- living bacteria (FLB). When flagellates were present, the 3-40% maximum breakthrough of fluorescent y labelled FLB injected into the microcosms was much lower than the 60-130% observed for killed controls Grazing and clearance rates (3-27 FLB flag-1 h-1 and 12-23 nI flag-1 h-1, respectively) calculated from the data were in the range reported for flagellates in other aqueous environments. The data provide evidence that flagellate bacterivory is an important control on groundwater FLB populations.
Cox, Carol J.; Sharma, Meenakshi; Leckman, James F.; Zuccolo, Jonathan; Zuccolo, Amir; Kovoor, Abraham; Swedo, Susan E.; Cunningham, Madeleine W.
2013-01-01
How autoantibodies target the brain and lead to disease in disorders such as Sydenham chorea (SC) is not known. SC is characterized by autoantibodies against the brain and is the main neurologic manifestation of streptococcal-induced rheumatic fever. Previously, our novel SC-derived mAb 24.3.1 was found to recognize streptococcal and brain antigens. To investigate in vivo targets of human mAb 24.3.1, VH/VL genes were expressed in B cells of transgenic (Tg) mice as functional chimeric human VH 24.3.1 - mouse constant region IgG1a autoantibody. Chimeric human-mouse IgG1a autoantibody co-localized with tyrosine hydroxylase in the basal ganglia within dopaminergic neurons in vivo in VH 24.3.1 Tg mice. Both human mAb 24.3.1 and IgG1a in Tg sera were found to react with human dopamine D2 receptor (D2R). Reactivity of chorea-derived mAb 24.3.1 or SC IgG with D2R was confirmed by 1) dose dependent inhibitory signaling of D2R as a potential consequence of targeting dopaminergic neurons, 2) reaction with surface-exposed FLAG epitope-tagged D2R, and 3) blocking of Ab reactivity by an extracellular D2R peptide. IgG from SC and a related subset of streptococcal associated behavioral disorders called pediatric autoimmune neuropsychiatric disorder associated with streptococci (PANDAS) with small choreiform movements reacted in ELISA with D2R. Reaction with FLAG-tagged D2R distinguished SC from PANDAS while sera from both SC and PANDAS induced inhibitory signaling of D2R on transfected cells comparable to dopamine. Here we define a mechanism by which the brain may be altered by antibody in movement and behavioral disorders. PMID:24184556
Brejchova, Jana; Vosahlikova, Miroslava; Roubalova, Lenka; Parenti, Marco; Mauri, Mario; Chernyavskiy, Oleksandr; Svoboda, Petr
2016-08-01
Decrease of cholesterol level in plasma membrane of living HEK293 cells transiently expressing FLAG-δ-OR by β-cyclodextrin (β-CDX) resulted in a slight internalization of δ-OR. Massive internalization of δ-OR induced by specific agonist DADLE was diminished in cholesterol-depleted cells. These results suggest that agonist-induced internalization of δ-OR, which has been traditionally attributed exclusively to clathrin-mediated pathway, proceeds at least partially via membrane domains. Identification of internalized pools of FLAG-δ-OR by colocalization studies with proteins of Rab family indicated the decreased presence of receptors in early endosomes (Rab5), late endosomes and lysosomes (Rab7) and fast recycling vesicles (Rab4). Slow type of recycling (Rab11) was unchanged by cholesterol depletion. As expected, agonist-induced internalization of oxytocin receptors was totally suppressed in β-CDX-treated cells. Determination of average fluorescence lifetime of TMA-DPH, the polar derivative of hydrophobic membrane probe diphenylhexatriene, in live cells by FLIM indicated a significant alteration of the overall PM structure which may be interpreted as an increased "water-accessible space" within PM area. Data obtained by studies of HEK293 cells transiently expressing FLAG-δ-OR by "antibody feeding" method were extended by analysis of the effect of cholesterol depletion on distribution of FLAG-δ-OR in sucrose density gradients prepared from HEK293 cells stably expressing FLAG-δ-OR. Major part of FLAG-δ-OR was co-localized with plasma membrane marker Na,K-ATPase and β-CDX treatment resulted in shift of PM fragments containing both FLAG-δ-OR and Na,K-ATPase to higher density. Thus, the decrease in content of the major lipid constituent of PM resulted in increased density of resulting PM fragments.
Challenges to Public Order and the Seas
2014-03-01
these excessive claims will ever be rolled back. Worse, they could be strengthened in a game of one- upmanship. A laissez faire approach to flag...to the rule of law and a basis for the conduct of af- fairs among nations. What is necessary for an effective system of ocean governance? This...gain an increased market share as reputable national flags decline. Depending on which FOC is involved, there is a fair probability that the flag state
2017-09-01
Toronto) which immunoprecipitates EpoR but works poorly in immunoblots and not at in immunohistochemistry (Hu et al., Kidney Int. 2013 Sep;84(3):468-81...DAPI EpoR/GFP/DAPIGFP/DAPI C.. Ba/F32EpoR2Flag2GFP.cells 9 Figure 4. Screening the new MAbs to human RopE. Human embryonic kidney -293 (HEK-293) cells...ontogeny of EpoR and RopE expression Figure 7. Concordant RopE and EpoR expression was observed in the lung (left) and the kidney (right) that increase
Divergent receiver responses to components of multimodal signals in two foot-flagging frog species.
Preininger, Doris; Boeckle, Markus; Sztatecsny, Marc; Hödl, Walter
2013-01-01
Multimodal communication of acoustic and visual signals serves a vital role in the mating system of anuran amphibians. To understand signal evolution and function in multimodal signal design it is critical to test receiver responses to unimodal signal components versus multimodal composite signals. We investigated two anuran species displaying a conspicuous foot-flagging behavior in addition to or in combination with advertisement calls while announcing their signaling sites to conspecifics. To investigate the conspicuousness of the foot-flagging signals, we measured and compared spectral reflectance of foot webbings of Micrixalus saxicola and Staurois parvus using a spectrophotometer. We performed behavioral field experiments using a model frog including an extendable leg combined with acoustic playbacks to test receiver responses to acoustic, visual and combined audio-visual stimuli. Our results indicated that the foot webbings of S. parvus achieved a 13 times higher contrast against their visual background than feet of M. saxicola. The main response to all experimental stimuli in S. parvus was foot flagging, whereas M. saxicola responded primarily with calls but never foot flagged. Together these across-species differences suggest that in S. parvus foot-flagging behavior is applied as a salient and frequently used communicative signal during agonistic behavior, whereas we propose it constitutes an evolutionary nascent state in ritualization of the current fighting behavior in M. saxicola.
NASA Astrophysics Data System (ADS)
Yu, Yuelong; Liu, Yingzheng; Chen, Yujia
2018-04-01
The influence of an inverted flag's length-to-channel-width ratio (C* = L/W) on its oscillating behavior in a channel flow and the resultant vortex dynamics and heat transfer are determined experimentally. Three systems with C* values of 0.125, 0.250, and 0.375 were chosen for comparison. The interaction of highly unsteady flow with the inverted flag is measured with time-resolved particle image velocimetry. Variations in the underlying flow physics are discussed in terms of the statistical flow quantities, flag displacement, phase-averaged flow field, and vortex dynamics. The results show that the increase in C* shifts the occurrence of the flapping regime at high dimensionless bending stiffness. With the flag in the flapping region, three distinct vortex dynamics—the von Kármán vortex street, the G mode, and the singular mode—are identified at C* values of 0.375, 0.250, and 0.125, respectively. Finally, the heat transfer enhancement from the self-oscillating inverted flag is measured to serve as complementary information to quantify the cause-and-effect relationship between vortex dynamics and wall heat transfer. The increase in C* strongly promotes wall heat removal because disruption of the boundary layer by the energetic vortices is substantially intensified. Among all systems, wall heat transfer removal is most efficient at the intermediate C* value of 0.250.
NASA Astrophysics Data System (ADS)
Shoele, Kourosh; Mittal, Rajat
2015-11-01
Piezoelectric flexible flags can be used to continuously generate energy for small-scale sensor used in a wide variety of applications ranging from measurement/monitoring of environmental conditions (outdoors or indoors) to in-situ tracking of wild animals. Here, we study the energy harvesting performance as well as the flow-structure interaction of an inverted piezoelectric flag. We use a coupled fluid-structure-electric solver to examine the dynamic response of the inverted flag as well as the associated vortical characteristics with different inertia and bending stiffness. Simulations indicate that large amplitude vibrations can be achieved over a large range of parameters over which lock-on between the flag flutter and the intrinsic wake shedding occurs. The effects of initial inclination of the flag to the prevailing flow as well as Reynolds number of the flow are explored, and the effect of piezoelectric material parameters on the energy harvesting performance of this flutter state is examined in detail. The maximum energy efficiency occurs when there is a match between the intrinsic timescales of flutter and the piezoelectric circuit. The simulations are used to formulate a scaling law that could be used to predict the energy harvesting performance of such devices. The support for this study comes from AFSOR, NSF, EPRI and Johns Hopkins E2SHI Seed Grant.
Zilio, Nicola; Boddy, Michael N
2017-03-01
The tandem affinity purification (TAP) method uses an epitope that contains two different affinity purification tags separated by a site-specific protease site to isolate a protein rapidly and easily. Proteins purified via the TAP tag are eluted under mild conditions, allowing them to be used for structural and biochemical analyses. The original TAP tag contains a calmodulin-binding peptide and the IgG-binding domain from protein A separated by a tobacco etch virus (TEV) protease cleavage site. After capturing the Protein A epitope on an IgG resin, bound proteins are released by incubation with the TEV protease and then isolated on a calmodulin matrix in the presence of calcium; elution from this resin is achieved by chelating calcium with EGTA. However, because the robustness of the calmodulin-binding step in this procedure is highly variable, we replaced the calmodulin-binding peptide with three copies of the FLAG epitope, (3× FLAG)-TEV-Protein A, which can be isolated using an anti-FLAG resin. Elution from this matrix is achieved in the presence of an excess of a 3× FLAG peptide. In addition to allowing proteins to be released under mild conditions, elution by the 3× FLAG peptide adds an extra layer of specificity to the TAP procedure, because it liberates only FLAG-tagged proteins. © 2017 Cold Spring Harbor Laboratory Press.
Code of Federal Regulations, 2011 CFR
2011-10-01
... a vest, shirt, or jacket of a color appropriate for daytime flagging such as orange, yellow, strong.... For nighttime flagging, similar outside garments shall be retro reflective. Acceptable hand signal...
Flagging threshold optimization for manual blood smear review in primary care laboratory.
Bihl, Pierre-Adrien
2018-04-01
Manual blood smear review is required when an anomaly detected by the automated hematologic analyzer triggers a flag. Our will through this study is to optimize these flagging thresholds for manual slide review in order to limit workload, while insuring clinical care through no extra false-negative. Flagging causes of 4,373 samples were investigated by manual slide review, after having been run on ADVIA 2120i. A set of 6 user-adjustments is proposed. By implementing all recommendations that we made, false-positive rate falls from 81.8% to 58.6%, while PPV increases from 18.2% to 23.7%. Hence, use of such optimized thresholds enables us to maximize efficiency without altering clinical care, but each laboratory should establish its own criteria to take into consideration local distinctive features.
Targeting Androgen Receptor by Lysosomal Degradation in Prostate Cancer
2015-11-01
transport of TFEB, Autophagy 8 (2012) 903-914. [7] J. Brugarolas, K. Lei , R.L. Hurley, B.D. Manning, J.H. Reiling, E. Hafen, L.A. Witters, L.W. Ellisen...chromatography ~ anti-FLAG immunoprecipitation B D EWS pos~t~on mass pept~ de 416-429 1449 .66 GDATVSYEDPPTAK 571-594 2289.08 GGPGGMRGGRGGLMDRGGPGGMFR...vector 1 2 3 -- FLAG-His EWS-Fii-1 4 5 6 - FLAG tubulin c RNA helicase A pos~t~on mass pept~ de 121-141 2161 .97 AENNSEVGASGYGVPGPTWDR 200-209
Analytic Simulation of the Performance of Mobile Maintenance Contact Teams
1985-05-01
RECTANGULAR THE CUSTOMERS, REQUIRING MAINT SERVICE, ARE ASSUMED DISTRIBUTED WITHIN A RECTANGLE WITH DIMENSIONS ARANGE ’BY BRANGE . THE POPULATION OF...AND SERVE A CUSTOMER. ’INPUTS: ’FLAG.DIST ’FLAG.FIFO I PR I NT ARANGE ’ BRANGE SPEED 4 POP ’NSERVE MTBF MTTR AN INTEGER FLAG TO INDICATE...TEAMlS). 81 READ ARANGE 32 PRINT ’I LINE THUS INPUT THE DEPTH CCROSS-FRONTAL; DIMENSION (KM; OF THE AREA OF THE TEAMiS;. 84 READ BRANGE
2010-07-04
ISS024-E-007376 (3 July 2010) --- NASA astronauts Shannon Walker and Doug Wheelock, both Expedition 24 flight engineers, pose for a photo with an American flag while aboard the International Space Station.
Rainbows: Stories and Customs from Around the World. Grades 3-6.
ERIC Educational Resources Information Center
Ahmed, Naseem
This book, appropriate for use in grades 3-6, presents information about nine regions of the world: Malaysia; Costa Rica; Taiwan; New Mexico, United States; Japan; India; Nigeria; Thailand; and China. Each region is presented in a three part format: (1) Background information provides a look at the geographical location, the flag, and the social…
APOLLO 17 - FLAG DEDICATION - JSC
1974-01-15
S74-15520 --- Left to right Gene Kranz, Gene Cernan, Karla Garnuch, Harrison Schmitt, George Abbey, and Sigurd A. Sjoberg watching the dedication of the Apollo 17 flag to the Mission Control Center. Photo credit: NASA
Interior detail of platform in main hall, with desk, flag, ...
Interior detail of platform in main hall, with desk, flag, and banners, facing south - International Longshoremen's & Warehousemen's Union Hall, Naval Civil Engineering Laboratory, Port Hueneme Road, Port Hueneme, Ventura County, CA
NASA Technical Reports Server (NTRS)
Katsaros, Kristina B.; Bhatti, Iftekhar; Mcmurdie, Lynn A.; Patty, Grant W.
1989-01-01
This paper describes some basic research techniques and algorithms developed to diagnose fronts in cyclonic storms over the ocean with data from satellite-borne microwave radiometers. Methods are developed for flagging strong gradients in integrated atmospheric water vapor and the presence of rain by using data from the SSMR on board the polar orbiting Seasat and Nimbus-7 satellites. Examination of 65 frontal systems showed that the water vapor gradient flag correctly identified 86 percent of the fronts, while the precipitation flagged 91 percent. The two types of flags emphasize different portions of the cyclone and are therefore complementary. Ultimately, these techniques are intended for operational use with data from the Special Sensor Microwave Imager which was launched in June 1987 on a satellite in the Defense Meteorological Satellite Program (DMSP).
Pavelko, Michael T.
2010-01-01
The water-level database for the Death Valley regional groundwater flow system in Nevada and California was updated. The database includes more than 54,000 water levels collected from 1907 to 2007, from more than 1,800 wells. Water levels were assigned a primary flag and multiple secondary flags that describe hydrologic conditions and trends at the time of the measurement and identify pertinent information about the well or water-level measurement. The flags provide a subjective measure of the relative accuracy of the measurements and are used to identify which water levels are appropriate for calculating head observations in a regional transient groundwater flow model. Included in the report appendix are all water-level data and their flags, selected well data, and an interactive spreadsheet for viewing hydrographs and well locations.
1980-09-01
WFLOR(2,3,4) IWAIT FOR FLAG CALL READEF(3,IUU) ICHECK 010 FLAG IF(IUU.NE.2) GO TO 587 IF(.NOT.LCONT) GO TO 999 K-K-54 IMAKE 7,8,9 LOOK LIKE 1,2,3 IF...K.EQ.-6) GO TO 999 IF(K.EQ.3) GO TO 223 IF(K.LT.1) GO TO 223 GO TO 588 587 CALL READEF(4,ITT) ICHECK 5 SEC FLAG IF(ITT.NE.2) GO TO 546 ISKIP IF NOT SET...ISEC,NESC,NYNESC,NESC 1092 FORMAT(’ ’,2A,"-Q’,’TIME 1,12o’s’,I2,2A,’l1, *-86- 1 A, 111A,AW GO TO 222 546 CALL READEF(2,ITS) ICHECK STOP FLAG IF
Li, Hua; Zhang, Feng-Lan; Shi, Wen-Jie; Bai, Xue-Jia; Jia, Shu-Qin; Zhang, Chen-Guang; Ding, Wei
2015-01-01
The technology of virus-based genetic modification in tissue engineering has provided the opportunity to produce more flexible and versatile biomaterials for transplantation. Localizing the transgene expression with increased efficiency is critical for tissue engineering as well as a challenge for virus-based gene delivery. In this study, we tagged the VP2 protein of type 2 adeno-associated virus (AAV) with a 3×FLAG plasmid at the N-terminus and packaged a FLAG-tagged recombinant AAV2 chimeric mutant. The mutant AAVs were immobilized onto the tissue engineering scaffolds with crosslinked anti-FLAG antibodies by N-succinimidyl-3-(2-pyridyldithiol) propionate (SPDP). Cultured cells were seeded to scaffolds to form 3D transplants, and then tested for viral transduction both in vitro and in vivo. The results showed that our FLAG-tagged AAV2 exerted similar transduction efficiency compared with the wild type AAV2 when infected cultured cells. Following immobilization onto the scaffolds of PLGA or gelatin sponge with anti-FLAG antibodies, the viral mediated transgene expression was significantly improved and more localized. Our data demonstrated that the mutation of AAV capsid targeted for antibody-based immobilization could be a practical approach for more efficient and precise transgene delivery. It was also suggested that the immobilization of AAV might have attractive potentials in applications of tissue engineering involving the targeted gene manipulation in 3D tissue cultures.
Karbowiak, Grzegorz; Vichová, Bronislavá; Slivinska, Kateryna; Werszko, Joanna; Didyk, Julia; Peťko, Branislav; Stanko, Michal; Akimov, Igor
2014-08-29
Tick occurrence was studied in the Chernobyl exclusion zone (CEZ) during the August-October 2009-2012. Dermacentor reticulatus ticks were collected using the flagging method and then screened for infection with Anaplasma phagocytophilum and Babesia canis by a PCR method incorporating specific primers and sequence analysis. The prevalence of infection with B. canis canis and A. phagocytophilum was found to be 3.41% and 25.36%, respectively. The results present the first evidence of B. canis canis and A. phagocytophilum in questing D. reticulatus ticks from the Chernobyl exclusion zone. They also reveal the presence of tick-borne disease foci in areas with no human activity, and confirm that they can be maintained in areas after a nuclear disaster with radioactive contamination. Copyright © 2014 Elsevier B.V. All rights reserved.
The French contribution to the voluntary observing ships network of sea surface salinity
NASA Astrophysics Data System (ADS)
Alory, G.; Delcroix, T.; Téchiné, P.; Diverrès, D.; Varillon, D.; Cravatte, S.; Gouriou, Y.; Grelet, J.; Jacquin, S.; Kestenare, E.; Maes, C.; Morrow, R.; Perrier, J.; Reverdin, G.; Roubaud, F.
2015-11-01
Sea Surface Salinity (SSS) is an essential climate variable that requires long term in situ observation. The French SSS Observation Service (SSS-OS) manages a network of Voluntary Observing Ships equipped with thermosalinographs (TSG). The network is global though more concentrated in the tropical Pacific and North Atlantic oceanic basins. The acquisition system is autonomous with real time transmission and is regularly serviced at harbor calls. There are distinct real time and delayed time processing chains. Real time processing includes automatic alerts to detect potential instrument problems, in case raw data are outside of climatic limits, and graphical monitoring tools. Delayed time processing relies on a dedicated software for attribution of data quality flags by visual inspection, and correction of TSG time series by comparison with daily water samples and collocated Argo data. A method for optimizing the automatic attribution of quality flags in real time, based on testing different thresholds for data deviation from climatology and retroactively comparing the resulting flags to delayed time flags, is presented. The SSS-OS real time data feed the Coriolis operational oceanography database, while the research-quality delayed time data can be extracted for selected time and geographical ranges through a graphical web interface. Delayed time data have been also combined with other SSS data sources to produce gridded files for the Pacific and Atlantic oceans. A short review of the research activities conducted with such data is given. It includes observation-based process-oriented and climate studies from regional to global scale as well as studies where in situ SSS is used for calibration/validation of models, coral proxies or satellite data.
The French Contribution to the Voluntary Observing Ships Network of Sea Surface Salinity
NASA Astrophysics Data System (ADS)
Delcroix, T. C.; Alory, G.; Téchiné, P.; Diverrès, D.; Varillon, D.; Cravatte, S. E.; Gouriou, Y.; Grelet, J.; Jacquin, S.; Kestenare, E.; Maes, C.; Morrow, R.; Perrier, J.; Reverdin, G. P.; Roubaud, F.
2016-02-01
Sea Surface Salinity (SSS) is an essential climate variable that requires long term in situ observation. The French SSS Observation Service (SSS-OS) manages a network of Voluntary Observing Ships equipped with thermosalinographs (TSG). The network is global though more concentrated in the tropical Pacific and North Atlantic oceanic basins. The acquisition system is autonomous with real time transmission and is regularly serviced at harbor calls. There are distinct real time and delayed time processing chains. Real time processing includes automatic alerts to detect potential instrument problems, in case raw data are outside of climatic limits, and graphical monitoring tools. Delayed time processing relies on a dedicated software for attribution of data quality flags by visual inspection, and correction of TSG time series by comparison with daily water samples and collocated Argo data. A method for optimizing the automatic attribution of quality flags in real time, based on testing different thresholds for data deviation from climatology and retroactively comparing the resulting flags to delayed time flags, is presented. The SSS-OS real time data feed the Coriolis operational oceanography database, while the research-quality delayed time data can be extracted for selected time and geographical ranges through a graphical web interface. Delayed time data have been also combined with other SSS data sources to produce gridded files for the Pacific and Atlantic oceans. A short review of the research activities conducted with such data is given. It includes observation-based process-oriented and climate studies from regional to global scale as well as studies where in situ SSS is used for calibration/validation of models, coral proxies or satellite data.
Taguchi-Shiobara, Fumio; Ota, Tatsuya; Ebana, Kaworu; Ookawa, Taiichiro; Yamasaki, Masanori; Tanabata, Takanari; Yamanouchi, Utako; Wu, Jianzhong; Ono, Nozomi; Nonoue, Yasunori; Nagata, Kazufumi; Fukuoka, Shuichi; Hirabayashi, Hideyuki; Yamamoto, Toshio; Yano, Masahiro
2015-10-01
We investigated the natural variations in the flag leaf morphology of rice. We conducted a principal component analysis based on nine flag leaf morphology traits using 103 accessions from the National Institute of Agrobiological Sciences Core Collection. The first component explained 39% of total variance, and the variable with highest loading was the width of the flag leaf (WFL). A genome-wide association analysis of 102 diverse Japanese accessions revealed that marker RM6992 on chromosome 4 was highly associated with WFL. In analyses of progenies derived from a cross between Takanari and Akenohoshi, the most significant quantitative trait locus (QTL) for WFL was in a 10.3-kb region containing the NARROW LEAF 1 (NAL1) gene, located 0.4 Mb downstream of RM6992. Analyses of chromosomal segment substitution lines indicated that a mutation (G1509A single-nucleotide mutation, causing an R233H amino acid substitution in NAL1) was present at the QTL. This explained 13 and 20% of total variability in WFL and the distance between small vascular bundles, respectively. The mutation apparently occurred during rice domestication and spread into japonica, tropical japonica, and indica subgroups. Notably, one accession, Phulba, had a NAL1 allele encoding only the N-terminal, or one-fourth, of the wild-type peptide. Given that the Phulba allele and the histidine-type allele showed essentially the same phenotype, the histidine-type allele was regarded as malfunctional. The phenotypes of transgenic plants varied depending on the ratio of histidine-type alleles to arginine-type alleles, raising the possibility that H(233)-type products function differently from and compete with R(233)-type products. Copyright © 2015 by the Genetics Society of America.
NASA Technical Reports Server (NTRS)
Enison, R. L.
1971-01-01
A computer program called Character String Scanner (CSS), is presented. It is designed to search a data set for any specified group of characters and then to flag this group. The output of the CSS program is a listing of the data set being searched with the specified group of characters being flagged by asterisks. Therefore, one may readily identify specific keywords, groups of keywords or specified lines of code internal to a computer program, in a program output, or in any other specific data set. Possible applications of this program include the automatic scan of an output data set for pertinent keyword data, the editing of a program to change the appearance of a certain word or group of words, and the conversion of a set of code to a different set of code.
Exposure to the American flag polarizes democratic-republican ideologies.
Chan, Eugene Y
2017-12-01
Some prior research has suggested that exposure to the American flag tilts Americans towards Republicanism, while others have proffered that it brings outs a common 'together' perspective instead. We explore a third possibility - that it may actually polarize Americans' political ideology. It is generally accepted that exposure to an environmental cue can shift attitudes and behaviours, at least partly or temporarily, in a manner that is consistent with that cue. Yet, the same cue can mean different things to different people. In the same vein, given how national identity and political ideology are intertwined in the United States, we hypothesize that the American flag should heighten different political beliefs depending on individuals' political ideology. To Democrats, being American is to support Democratic values, but to Republicans, being American is to support Republican values. The American flag thus should heighten Democrats of their Democratic identity, and it should heighten Republicans of their Republican one. The results of an experiment with 752 American respondents who were representative of the US population supported this polarizing effect of the American flag. The theoretical and policy implications of the findings are offered. © 2017 The British Psychological Society.
Friman, Patrick C
2010-01-01
At last, the field of applied behavior analysis has a beautifully crafted, true textbook that can proudly stand cover to cover and spine to spine beside any of the expensive, imposing, and ornately designed textbooks used by college instructors who teach courses in conventional areas of education or psychology. In this review, I fully laud this development, credit Cooper, Heron, and Heward for making it happen, argue that it signifies a checkered flag for students and professors, and recommend the book for classes in applied behavior analysis everywhere. Subsequently, I review its chapters, each of which could easily stand alone as publications in their own right. Finally, I supply a cautionary note, a yellow flag to accompany the well-earned checkered flag, by pointing out that, as is true with all general textbooks on applied behavior analysis, a major portion of the references involves research on persons who occupy only a tail of the normal distribution. To attain the mainstream role Skinner envisioned and most (if not all) behavior analysts desire, the field will have to increase its focus on persons who reside under the dome of that distribution.
1985-01-01
S85-28989 (March 1985) --- The dominant features of the STS-51D emblem are an orbit formed by a Colonial American flag and a space shuttle. The flag in orbit signifies the U.S. flag to indicate that it comes from this country and the American people. The original 13-star flag is used to symbolize a continuity of technical achievement and progress since colonial times. The name Discovery preceding the flag represents the spirit of Discovery and exploration of new frontiers which have been a hallmark of American people even before they were formed together as a nation. The crew members are Karol J. Bobko, Donald E. Williams, Rhea Seddon, S. David Griggs and Jeffrey A. Hoffman of NASA; and Charles D. Walker, representing McDonnell Douglas Corporation; and U. S. Senator Jake Garn. The NASA insignia design for space shuttle flights is reserved for use by the astronauts and for other official use as the NASA Administrator may authorize. Public availability has been approved only in the forms of illustrations by the various news media. When and if there is any change in this policy, which is not anticipated, the change will be publicly announced. Photo credit: NASA
Purification of FLAG-tagged Secreted Proteins from Mammalian Cells
Itakura, Eisuke; Chen, Changchun; de Bono, Mario
2017-01-01
This protocol describes a method for purifying glycosylated FLAG-tagged secreted proteins with disulfide bonds from mammalian cells. The purified products can be used for various applications, such as ligand binding assays. PMID:29075655
38. FLAG/ADMIRAL BRIDGE PORT LOOKING TO STARBOARD SHOWING RADAR ...
38. FLAG/ADMIRAL BRIDGE - PORT LOOKING TO STARBOARD SHOWING RADAR SCOPE, ADMIRAL'S CHAIR, GYRO REPEATER AND VARIOUS COMMUNICATION SYSTEMS. - U.S.S. HORNET, Puget Sound Naval Shipyard, Sinclair Inlet, Bremerton, Kitsap County, WA
6. ADMINISTRATION BUILDING WITH FLAG POLE, LOOKING SOUTH. NIKE ...
6. ADMINISTRATION BUILDING WITH FLAG POLE, LOOKING SOUTH. - NIKE Missile Base SL-40, Administration Building, East central portion of base, southeast of Mess Hall, northeast of HIPAR Equipment Building, Hecker, Monroe County, IL
Assessment of advanced warning signs for flagging operations.
DOT National Transportation Integrated Search
1999-05-01
The Virginia Department of Transportation (VDOT) and several other state departments : of transportation have expressed interest in modifying the advanced warning sign for work zone : flagging operations. The advanced warning sign is intended to aler...
Novel Function of NIBP in Breast Cancer
2012-05-01
reduced in NIBP knockdown cells (Fig. 8). 7 pRK -Flag-NIBP Isoforms(aa) 960 944 1200 1246 1148 S E A P A c ti v it y ( F o ld...Fig.9. MDA-MB-231 cells were co-transfected by TurboFectin8.0 with empty pRK -Flag vector or various isoforms of NIBP with NF-B-SEAP reporter and...Ser536) pRK -Flag 12060301550 NIBP-mutA 12060301550TNFα (min) Fig.11. MDA-MB-231 cells at 60% confluence in 6-well plates were transfected with empty
2007-04-02
KENNEDY SPACE CENTER, FLA. -- The American flag and the NASA logo shine in the morning sun on the side of the Vehicle Assembly Building after completion of their repainting. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The NASA logo, which is known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. Photo credit: NASA/Jim Grossmann
1979-12-01
BE2 CD66 ALl SGG/110(14) 5/AS2 SGG/79(14) AMI 110(13) 5/AU2 78(16) NI KRIRF/lll(2) ANl PRIRF/lll(l) ARI IPC/lll(ll) 7/BPl IPC/144(4) ASI KRF/106(9...KRS 6034 Read a character from the keyboard/reader buffer. The keyboard/reader flag is set when the operation is completed. KIE 6035 Enable the...keyboard/ reader flag is a 1. KCC 6032 Clear the AC and the keyboard/reader flag. KRS 6034 Read a character from the keyboard/reader buffer. The keyboard
ERIC Educational Resources Information Center
Taylor, Kelley R.
2010-01-01
This article presents a sample legal battle that illustrates school officials' "reasonable forecasts" of substantial disruption in the school environment. In 2006, two students from a Texas high school came to school carrying purses decorated with images of the Confederate flag. The school district has a zero-tolerance policy for…
ERIC Educational Resources Information Center
Classroom Computer Learning, 1984
1984-01-01
Presents six computer-oriented classroom activities. They include: surveying a house for products using microprocessors, writing a program to display a flag, experimenting with LOGO's graphics capabilities, writing stories on the computer, using FOR/NEXT commands to create a blinking object, and teaching the Milton Bradley Big Trak to play…
The flagellar protein FLAG1/SMP1 is a candidate for Leishmania-sand fly interaction.
Di-Blasi, Tatiana; Lobo, Amanda R; Nascimento, Luanda M; Córdova-Rojas, Jose L; Pestana, Karen; Marín-Villa, Marcel; Tempone, Antonio J; Telleria, Erich L; Ramalho-Ortigão, Marcelo; McMahon-Pratt, Diane; Traub-Csekö, Yara M
2015-03-01
Leishmaniasis is a serious problem that affects mostly poor countries. Various species of Leishmania are the agents of the disease, which take different clinical manifestations. The parasite is transmitted by sandflies, predominantly from the Phlebotomus genus in the Old World and Lutzomyia in the New World. During development in the gut, Leishmania must survive various challenges, which include avoiding being expelled with blood remnants after digestion. It is believed that attachment to the gut epithelium is a necessary step for vector infection, and molecules from parasites and sand flies have been implicated in this attachment. In previous work, monoclonal antibodies were produced against Leishmania. Among these an antibody was obtained against Leishmania braziliensis flagella, which blocked the attachment of Leishmania panamensis flagella to Phlebotomus papatasi guts. The protein recognized by this antibody was identified and named FLAG1, and the complete FLAG1 gene sequence was obtained. This protein was later independently identified as a small, myristoylated protein and called SMP1, so from now on it will be denominated FLAG1/SMP1. The FLAG1/SMP1 gene is expressed in all developmental stages of the parasite, but has higher expression in promastigotes. The anti-FLAG1/SMP1 antibody recognized the flagellum of all Leishmania species tested and generated the expected band by western blots. This antibody was used in attachment and infection blocking experiments. Using the New World vector Lutzomyia longipalpis and Leishmania infantum chagasi, no inhibition of attachment ex vivo or infection in vivo was seen. On the other hand, when the Old World vectors P. papatasi and Leishmania major were used, a significant decrease of both attachment and infection were seen in the presence of the antibody. We propose that FLAG1/SMP1 is involved in the attachment/infection of Leishmania in the strict vector P. papatasi and not the permissive vector L. longipalpis.
Influence of deer abundance on the abundance of questing adult Ixodes scapularis (Acari: Ixodidae)
Ginsberg, H.S.; Zhioua, E.
1999-01-01
Nymphal and adult Ixodes scapularis Say were sampled by flagging at 2 sites on a barrier island, Fire Island, NY, and at 2 sites on the nearby mainland. Nymphal densities did not differ consistently between island and mainland sites, but adult densities were consistently lower on the island. We tested whether lower adult densities on the island resulted from greater nymphal mortality on the island than the mainland, or whether adult ticks on the island were poorly sampled by flagging because they had attached abundantly to deer, which were common on Fire Island. Differential nymphal mortality on islands vs. mainland did not explain this difference in adult densities because survival of flat and engorged nymphs in enclosures was the same at island and mainland sites. Ticks were infected by parasitic wasps on the island and not the mainland, but the infection rate (4.3%) was too low to explain the difference in adult tick densities. In contrast, exclusion of deer by game fencing on Fire Island resulted in markedly increased numbers of adult ticks in flagging samples inside compared to samples taken outside the exclosures. Therefore, the scarcity of adult ticks in flagging samples on Fire Island resulted, at least in part, from the ticks being unavailable to flagging samples because they were on deer hosts. Differences in the densities of flagged ticks inside and outside the exclosures were used to estimate the percentage of questing adults on Fire Island that found deer hosts, excluding those that attached to other host species. Approximately 56% of these questing adult ticks found deer hosts in 1995 and 50% found deer hosts in 1996. Therefore, in areas where vertebrate hosts are highly abundant, large proportions of the questing tick population can find hosts. Moreover, comparisons of tick densities at different sites by flagging can potentially be biased by differences in host densities among sites.
Gurieva, Tanya; Bootsma, Martin C J; Bonten, Marc J M
2013-01-01
Nosocomial infection rates due to antibiotic-resistant bacteriae, e.g., methicillin-resistant Staphylococcus aureus (MRSA) remain high in most countries. Screening for MRSA carriage followed by barrier precautions for documented carriers (so-called screen and isolate (S&I)) has been successful in some, but not all settings. Moreover, different strategies have been proposed, but comparative studies determining their relative effects and costs are not available. We, therefore, used a mathematical model to evaluate the effect and costs of different S&I strategies and to identify the critical parameters for this outcome. The dynamic stochastic simulation model consists of 3 hospitals with general wards and intensive care units (ICUs) and incorporates readmission of carriers of MRSA. Patient flow between ICUs and wards was based on real observations. Baseline prevalence of MRSA was set at 20% in ICUs and hospital-wide at 5%; ranges of costs and infection rates were based on published data. Four S&I strategies were compared to a do-nothing scenario: S&I of previously documented carriers ("flagged" patients); S&I of flagged patients and ICU admissions; S&I of flagged and group of "frequent" patients; S&I of all hospital admissions (universal screening). Evaluated levels of efficacy of S&I were 10%, 25%, 50% and 100%. Our model predicts that S&I of flagged and S&I of flagged and ICU patients are the most cost-saving strategies with fastest return of investment. For low isolation efficacy universal screening and S&I of flagged and "frequent" patients may never become cost-saving. Universal screening is predicted to prevent hardly more infections than S&I of flagged and "frequent" patients, albeit at higher costs. Whether an intervention becomes cost-saving within 10 years critically depends on costs per infection in ICU, costs of screening and isolation efficacy.
Primer in Genetics and Genomics, Article 4-Inheritance Patterns.
Aiello, Lisa B; Chiatti, Beth Desaretz
2017-07-01
Since the completion of the Human Genome Project, much has been uncovered about inheritance of various illnesses and disorders. There are two main types of inheritance: Mendelian and non-Mendelian. Mendelian inheritance includes autosomal dominant, autosomal recessive, X-linked, and Y-linked inheritance. Non-Mendelian inheritance includes mitochondrial and multifactorial inheritance. Nurses must understand the types of inheritance in order to identify red flags that may indicate the possibility of a hereditary disorder in a patient or family.
Pseudo-Kähler Quantization on Flag Manifolds
NASA Astrophysics Data System (ADS)
Karabegov, Alexander V.
A unified approach to geometric, symbol and deformation quantizations on a generalized flag manifold endowed with an invariant pseudo-Kähler structure is proposed. In particular cases we arrive at Berezin's quantization via covariant and contravariant symbols.
Bernard J. Cigrand, DDS: Father of Flag Day and renaissance man.
Spiegel, Allen D; Kavaler, Florence
2007-06-01
Dr. Bernard J. Cigrand is acknowledged as the "Father of Flag Day." He relentlessly continued his activities for more than sixty years to have June 14 designated for the national observance of the birth of the American flag. That finally occurred in 1948, seventeen years after his death, when President Harry S. Truman signed a Congressional Act into law. However, the law designated a voluntary observance but did not create a legal national holiday. In addition to his fervent passion for Flag Day, Cigrand undertook a variety of other initiatives He was a practicing dentist, the dean of a dental school, an investigative journalist, an expert on heraldry and seals, a lecturer and an author of books. Despite all his achievements, Cigrand is more widely known in the European country from where his parents emigrated to the United States in 1852 - Luxembourg, than in the United States.
Synthesis and materialization of a reaction-diffusion French flag pattern
NASA Astrophysics Data System (ADS)
Zadorin, Anton S.; Rondelez, Yannick; Gines, Guillaume; Dilhas, Vadim; Urtel, Georg; Zambrano, Adrian; Galas, Jean-Christophe; Estevez-Torres, André
2017-10-01
During embryo development, patterns of protein concentration appear in response to morphogen gradients. These patterns provide spatial and chemical information that directs the fate of the underlying cells. Here, we emulate this process within non-living matter and demonstrate the autonomous structuration of a synthetic material. First, we use DNA-based reaction networks to synthesize a French flag, an archetypal pattern composed of three chemically distinct zones with sharp borders whose synthetic analogue has remained elusive. A bistable network within a shallow concentration gradient creates an immobile, sharp and long-lasting concentration front through a reaction-diffusion mechanism. The combination of two bistable circuits generates a French flag pattern whose 'phenotype' can be reprogrammed by network mutation. Second, these concentration patterns control the macroscopic organization of DNA-decorated particles, inducing a French flag pattern of colloidal aggregation. This experimental framework could be used to test reaction-diffusion models and fabricate soft materials following an autonomous developmental programme.
1998-08-11
Painters are suspended on platforms from the top of the 525-foot-high Vehicle Assembly Building (VAB) at KSC during repainting of the American flag. The flag spans an area 209 feet by 110 feet and will require 510 gallons of red, white and blue paint. Each stripe of the flag is 9 feet wide and each star is 6 feet in diameter. The platforms are operated by two electric motors and travel 35 feet per minute. Work is being done with rollers, with brushes being used for details. The paint was donated by ICI Devoe of Louisville, Ky. In addition to the flag, the Bicentennial Emblem on the other side of the VAB doors is being replaced by the NASA logo, honoring NASA’s 40th anniversary (in October). The logo covers an area 110 feet by 132 feet. Work is expected to be completed in mid-September
The American flag on the VAB is being repainted
NASA Technical Reports Server (NTRS)
1998-01-01
Painters are suspended on platforms from the top of the 525-foot- high Vehicle Assembly Building (VAB) at KSC during repainting of the American flag and NASA logo. The flag spans an area 209 feet by 110 feet and will require 510 gallons of red, white and blue paint. Each stripe of the flag is 9 feet wide and each star is 6 feet in diameter. The previous Bicentennial Emblem on the other side of the VAB doors is being replaced by the NASA logo, honoring NASA's 40th anniversary (in October). The logo covers an area 110 feet by 132 feet. The painting platforms are operated by two electric motors and travel 35 feet per minute. Work is being done with rollers, with brushes being used for details. The paint was donated by ICI Devoe of Louisville, Ky. Work is expected to be completed in mid-September.
Continued Development of the Solar System Concept Inventory
NASA Astrophysics Data System (ADS)
Hornstein, Seth D.; Prather, E. E.; English, T. R.; Desch, S. M.; Keller, J. M.; CATS
2010-01-01
The Solar System Concept Inventory (SSCI) was developed in order to provide a pre-/post-instruction assessment instrument suitable for use in an introductory solar system course. The topics included on the SSCI focus on formation mechanisms, planetary interiors, atmospheric and surface effects, and small solar system bodies. These topics were selected by having faculty identify the key concepts they address when teaching about the solar system. Student interviews were then conducted to identify common naive ideas and reasoning difficulties relating to these key topics. As of December 2009, the SSCI has been through four semesters of both pre- and post-instruction classroom testing, involving over 2000 students and 11 institutions (ranging from two-year colleges to doctoral/research universities). After each semester of testing, item analysis statistics such as point biserial, percentage correct on pre- or post-testing, and frequently-chosen distracters (incorrect answers) were used to flag ineffective questions. Flagged questions were revised or eliminated. We present an overall outline of the SSCI development as well as our question-flagging criteria and question analyses from the latest round of field-testing. We would like to thank the NSF for funding under Grant No. 0715517, a CCLI Phase III Grant for the Collaboration of Astronomy Teaching Scholars (CATS) Program.
Hernández-Moreno, David; Soffers, Ans E M F; Wiratno; Falke, Hein E; Rietjens, Ivonne M C M; Murk, Albertinka J
2013-06-01
This study presents a consumer and farmer safety evaluation on the use of four botanical pesticides in pepper berry crop protection. The pesticides evaluated include preparations from clove, tuba root, sweet flag and pyrethrum. Their safety evaluation was based on their active ingredients being eugenol, rotenone, β-asarone and pyrethrins, respectively. Botanical pesticides from Acorus calamus are of possible concern because of the genotoxic and carcinogenic ingredient β-asarone although estimated margins of exposure (MOE) for consumers indicate a low priority for risk management. For the other three botanical pesticides the margin of safety (MOS) between established acute reference doses and/or acceptable daily intake values and intake estimates for the consumer, resulting from their use as a botanical pesticide are not of safety concern, with the exception for levels of rotenone upon use of tuba root extracts on stored berries. Used levels of clove and pyrethrum as botanical pesticides in pepper berry crop production is not of safety concern for consumers or farmers, whereas for use of tuba root and sweet flag some risk factors were defined requiring further evaluation and/or risk management. It seems prudent to look for alternatives for use of sweet flag extracts containing β-asarone. Copyright © 2013 Elsevier Ltd. All rights reserved.
The impact of testing accommodations on MCAT scores: descriptive results.
Julian, Ellen R; Ingersoll, Deborah J; Etienne, Patricia M; Hilger, Anthony E
2004-04-01
Medical College Admission Test (MCAT) examinees with disabilities who receive accommodations receive flagged scores indicating nonstandard administration. This report compares MCAT examinees who received accommodations and their performances with standard examinees. Aggregate history records of all 1994-2000 MCAT examinees were identified as flagged (2,401) or standard (297,880), then further sorted by race/ethnicity (broadly identified as underrepresented minority and non-URM, at the time of testing) and gender. Those with flagged scores were also classified by disability (LD = learning disability, ADHD = attention deficit hyperactivity disorder, LD/ADHD = learning disability and attention deficit hyperactivity disorder, and Other = other disability) and type of accommodation. Mean MCAT scores were calculated for all groups. A group of 866 examinees took the MCAT first as a standard administration and subsequently with accommodations. In a separate analysis, their two sets of scores were compared. Less than 1% of examinees (2,401) had accommodations; of these, 55% were LD, 17% ADHD, 5% LD/ADHD, and 23% Other. Extended time was the most frequently provided accommodation. Mean flagged scores slightly exceeded mean standard scores on all MCAT sections. Examinees who retook the MCAT with accommodations after a standard administration increased their scores by six points, quadrupling the average gain Standard-Standard retest cohort from another study. The small but statistically significant different higher flagged scores may reflect either appropriate compensation or overly generous accommodations. Extended time had a positive impact on the scores of those who retested with this accommodation. The validity the flagged MCAT in predicting success in medical school is not known, and further investigation is underway.
Gene transfer to the cerebellum.
Louboutin, Jean-Pierre; Reyes, Beverly A S; Van Bockstaele, Elisabeth J; Strayer, David S
2010-12-01
There are several diseases for which gene transfer therapy to the cerebellum might be practicable. In these studies, we used recombinant Tag-deleted SV40-derived vectors (rSV40s) to study gene delivery targeting the cerebellum. These vectors transduce neurons and microglia very effectively in vitro and in vivo, and so we tested them to evaluate gene transfer to the cerebellum in vivo. Using a rSV40 vector carrying human immunodeficiency virus (HIV)-Nef with a C-terminal FLAG epitope, we characterized the distribution, duration, and cell types transduced. Rats received test and control vectors by stereotaxic injection into the cerebellum. Transgene expression was assessed 1, 2, and 4 weeks later by immunostaining of serial brain sections. FLAG epitope-expressing cells were seen, at all times after vector administration, principally detected in the Purkinje cells of the cerebellum, identified as immunopositive for calbindin. Occasional microglial cells were tranduced; transgene expression was not detected in astrocytes or oligodendrocytes. No inflammatory or other reaction was detected at any time. Thus, SV40-derived vectors can deliver effective, safe, and durable transgene expression to the cerebellum.
USDA Forest Service
1981-01-01
Flagging (dead branch tips) on jack pine and red pine may be caused by insects, diseases, or mechanical damage. In the Lake States, flagging is often the result of mechanical damage, sometimes girdling, caused when the cones are torn off by red squirrels.
78 FR 35101 - Flag Day and National Flag Week, 2013
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-12
... Glory has followed, reminding us of the rights and responsibilities we share as citizens. This week, we celebrate that legacy, and we honor the brave men and women who have secured it through centuries of service...
46 CFR 154.17 - U.S. flag vessel: Certificate of Inspection endorsement.
Code of Federal Regulations, 2013 CFR
2013-10-01
... DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.17.... flag vessel allowed to carry a liquefied gas listed in Table 4 has the following endorsement for each...
46 CFR 154.17 - U.S. flag vessel: Certificate of Inspection endorsement.
Code of Federal Regulations, 2014 CFR
2014-10-01
... DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.17.... flag vessel allowed to carry a liquefied gas listed in Table 4 has the following endorsement for each...
46 CFR 154.17 - U.S. flag vessel: Certificate of Inspection endorsement.
Code of Federal Regulations, 2012 CFR
2012-10-01
... DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.17.... flag vessel allowed to carry a liquefied gas listed in Table 4 has the following endorsement for each...
Multifunctional nanoparticles as simulants for a gravimetric immunoassay.
Miller, Scott A; Hiatt, Leslie A; Keil, Robert G; Wright, David W; Cliffel, David E
2011-01-01
Immunoassays are important tools for the rapid detection and identification of pathogens, both clinically and in the research laboratory. An immunoassay with the potential for the detection of influenza was developed and tested using hemagglutinin (HA), a commonly studied glycoprotein found on the surface of influenza virions. Gold nanoparticles were synthesized, which present multiple peptide epitopes, including the HA epitope, in order to increase the gravimetric response achieved with the use of a QCM immunosensor for influenza. Specifically, epitopes associated with HA and FLAG peptides were affixed to gold nanoparticles by a six-mer PEG spacer between the epitope and the terminal cysteine. The PEG spacer was shown to enhance the probability for interaction with antibodies by increasing the distance the epitope extends from the gold surface. These nanoparticles were characterized using thermogravimetric analysis, transmission electron microscopy, matrix-assisted laser desorption/ionization-time of flight, and (1)H nuclear magnetic resonance analysis. Anti-FLAG and anti-HA antibodies were adhered to the surface of a QCM, and the response of each antibody upon exposure to HA, FLAG, and dual functionalized nanoparticles was compared with binding of Au-tiopronin nanoparticles and H5 HA proteins from influenza virus (H5N1). Results demonstrate that the immunoassay was capable of differentiating between nanoparticles presenting orthogonal epitopes in real-time with minimal nonspecific binding. The detection of H5 HA protein demonstrates the logical extension of using these nanoparticle mimics as a safe positive control in the detection of influenza, making this a vital step in improving influenza detection methodology.
Astronaut Harrison Schmitt next to deployed U.S. flag on lunar surface
1972-12-13
AS17-134-20384 (7-19 Dec. 1972) --- Scientist-astronaut Harrison H. Schmitt, lunar module pilot, is photographed next to the deployed United States flag during lunar surface extravehicular activity (EVA) at the Taurus-Littrow landing site. The highest part of the flag appears to point toward our planet Earth in the distant background. This picture was taken by astronaut Eugene A. Cernan, Apollo 17 commander. While astronauts Cernan and Schmitt descended in the Lunar Module (LM) to explore the moon, astronaut Ronald E. Evans, command module pilot, remained with the Command and Service Modules (CSM) in lunar orbit.
2002-11-10
KENNEDY SPACE CENTER, FLA. -- Seminole Native American Veterans serve as color guard during a pre-launch Native American ceremony at the Rocket Garden in the KSC Visitor Complex. David Nunez, U.S. Navy, carries the State of Florida Flag; David Stephen Bowers, U.S. Army, carries the Flag of the United States of America; Charles Billie Hiers, U.S. Marine Corps., carries the Seminole Tribe of Florida Flag. The ceremony was part of several days' activities commemorating John B. Herrington as the first tribally enrolled Native American astronaut to fly on a Shuttle mission. Herrington is a Mission Specialist on STS-113.
Rankin, Anne
2015-01-01
Physiotherapists use red flags to screen for serious pathology. Paediatric osteosarcoma is a rare disease, occurring predominantly in the area of the knee and shoulder, and it is not always included by physiotherapists on a differential diagnosis list. Traditional red flags do not always correspond to the initial signs and symptoms of osteosarcoma. Physiotherapists should routinely palpate along the length of the bone to detect a potential mass. The detection of a mass or symptoms that do not follow the expected course indicates the need for reassessment and possibly referral for further investigation.
2007-04-02
KENNEDY SPACE CENTER, FLA. -- The NASA logo shines in the morning sun on the side of the Vehicle Assembly Building after completion of its repainting. The logo, which is known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. The American flag was also painted on the side of the VAB. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. Photo credit: NASA/Jim Grossmann
NASA Astrophysics Data System (ADS)
Zeilik, M.; Garvin-Doxas, K.
2003-12-01
FLAG, the Field-tested Learning Assessment Guide (http://www.flaguide.org/) is a NSF funded website that offers broadly-applicable, self-contained modular classroom assessment techniques (CATs) and discipline-specific tools for STEM instructors creating new approaches to evaluate student learning, attitudes and performance. In particular, the FLAG contains proven techniques for alterative assessments---those needed for reformed, innovative STEM courses. Each tool has been developed, tested and refined in real classrooms at colleges and universities. The FLAG also contains an assessment primer, a section to help you select the most appropriate assessment technique(s) for your course goals, and other resources. In addition to references on instrument development and field-tested instruments on attitudes towards science, the FLAG also includes discipline-specific tools in Physics, Astronomy, Biology, and Mathematics. Building of the Geoscience collection is currently under way with the development of an instrument for detecting misconceptions of incoming freshmen on Space Science, which is being developed with the help of the Committee on Space Science and Astronomy of the American Association of Physics Teachers. Additional field-tested resources from the Geosciences are solicited from the community. Contributions should be sent to Michael Zeilik, zeilik@la.unm.edu. This work has been supported in part by NSF grant DUE 99-81155.
Navigating recurrent abdominal pain through clinical clues, red flags, and initial testing.
Noe, Joshua D; Li, B U K
2009-05-01
Recurrent abdominal pain is a common chronic complaint that presents to your office. The constant challenge is one of detecting those with organic disease from the majority who have a functional pain disorder including functional dyspepsia, irritable bowel syndrome, functional abdominal pain, and abdominal migraine. Beginning with a detailed history and physical exam, you can: 1) apply the symptom-based Rome III criteria to positively identify a functional disorder, and 2) filter these findings through the diagnostic clues and red flags that point toward specific organic disease and/or further testing. Once a functional diagnosis has been made or an organic disease is suspected, you can initiate a self-limited empiric therapeutic trial. With this diagnostic approach, you should feel confident navigating through the initial evaluation, management, and consultation referral for a child or adolescent with recurrent abdominal pain.
Serendipitous observations of asteroids in Herschel PACS and SPIRE maps
NASA Astrophysics Data System (ADS)
Szakáts, R.; Kiss, Cs.; Marton, G.; Varga-Verebélyi, E.; Müller, T.; Pál, A.
2017-09-01
We present our methods and results in finding serendipitous solar system objects on Herschel PACS and SPIRE maps. We can use this data to supplement the Herschel PACS and SPIRE point source catalogs with flags of possible contamination and to obtain thermal infrared fluxes for these asteroids.
Snoezelen[R]: Empirical Review of Product Representation
ERIC Educational Resources Information Center
Botts, Betsy H.; Hershfeldt, Patti A.; Christensen-Sandfort, Robyn J.
2008-01-01
The purpose of this study was to critically review the empirical evidence surrounding three assertions presented by FlagHouse concerning Snoezelen[R] environments in day school public education settings. Given the absence of empirical literature examining the use of Snoezelen[R] in day school settings, the authors analyzed five studies that were…
China Report RED FLAG NO. 4, 16 FEBRUARY 1986.
1986-04-14
put forward the idea of genetic determinism is to prove their theory of " selfish human nature." Dawkins in his book "The Selfish Gene " said: "An...while genes are everlasting. Genes are selfish and have a ten- dency to expand themselves without limit. Genes control the organism and genes ...control behavior, and all social behavior can be explained in terms of the theory of selfish genes . From this, they put forward the ideas of the
Molecular Studies on MIC1/PDF in Human Prostate Cancer
2005-09-01
expression of secreted MIC-1 protein (Aim 2). Moreover, the functions of MIC-1 have been studied in vitro by using specific antibody directed against MIC-1... antibody M2 (Sigma). The FLAG tag was inserted at the 3’-translated region of the MIC-l/PDF cDNA. A double stranded, synthetic oligonucleotide was designed...B) Lower panel showed the coomassie blue of specific antibody directed against stained gel as a loading control. MIC-1 protein. More specifically
China Report, Red Flag, No. 8, 16 April 1983
1983-07-01
teachers in our country rank very low in both their pay and social position. So, no one is willing to be a pri- mary school teacher. Unqualified ...man’s knowledge of natural laws brings with it increases in man’s means to exert an effect on the natural world." ("Collected Works of Marx and Engels...the wealth of human knowledge and the new knowledge and fruits of contemporary science and culture. Freedom cannot be 11 attained until the law of
2014-05-21
CAPE CANAVERAL, Fla. – Members of the West Virginia University color guard stand at attention during presentation of the U.S. Flag at the opening ceremony of NASA’s 2014 Robotics Mining Competition at the Kennedy Space Center Visitor Complex in Florida. More than 35 teams from around the U.S. have designed and built remote-controlled robots for the mining competition. The competition is a NASA Human Exploration and Operations Mission Directorate project designed to engage and retain students in science, technology, engineering and mathematics, or STEM, fields by expanding opportunities for student research and design. Teams use their remote-controlled robotics to maneuver and dig in a supersized sandbox filled with a crushed material that has characteristics similar to Martian soil. The objective of the challenge is to see which team’s robot can collect and move the most regolith within a specified amount of time. For more information, visit www.nasa.gov/nasarmc. Photo credit: NASA/Frankie Martin
Bergua, Juan M; Montesinos, Pau; Martinez-Cuadrón, David; Fernández-Abellán, Pascual; Serrano, Josefina; Sayas, María J; Prieto-Fernandez, Julio; García, Raimundo; García-Huerta, Ana J; Barrios, Manuel; Benavente, Celina; Pérez-Encinas, Manuel; Simiele, Adriana; Rodríguez-Macias, Gabriela; Herrera-Puente, Pilar; Rodríguez-Veiga, Rebeca; Martínez-Sánchez, María P; Amador-Barciela, María L; Riaza-Grau, Rosalía; Sanz, Miguel A
2016-09-01
The combination of fludarabine, cytarabine, idarubicin, and granulocyte colony-stimulating factor (FLAG-Ida) is widely used in relapsed/refractory acute myeloid leukaemia (AML). We retrospectively analysed the results of 259 adult AML patients treated as first salvage with FLAG-Ida or FLAG-Ida plus Gentuzumab-Ozogamicin (FLAGO-Ida) of the Programa Español de Tratamientos en Hematología (PETHEMA) database, developing a prognostic score system of survival in this setting (SALFLAGE score). Overall, 221 patients received FLAG-Ida and 38 FLAGO-Ida; 92 were older than 60 years. The complete remission (CR)/CR with incomplete blood count recovery (CRi) rate was 51%, with 9% of induction deaths. Three covariates were associated with lower CR/CRi: high-risk cytogenetics and t(8;21) at diagnosis, no previous allogeneic stem cell transplantation (allo-SCT) and relapse-free interval <1 year. Allo-SCT was performed in second CR in 60 patients (23%). The median overall survival (OS) of the entire cohort was 0·7 years, with 22% OS at 5-years. Four independent variables were used to construct the score: cytogenetics, FLT3-internal tandem duplication, length of relapse-free interval and previous allo-SCT. Using this stratification system, three groups were defined: favourable (26% of patients), intermediate (29%) and poor-risk (45%), with an expected 5-year OS of 52%, 26% and 7%, respectively. The SALFLAGE score discriminated a subset of patients with an acceptable long-term outcome using FLAG-Ida/FLAGO-Ida regimen. The results of this retrospective analysis should be validated in independent external cohorts. © 2016 John Wiley & Sons Ltd.
Official portrait of Astronaut Anna L. Fisher
NASA Technical Reports Server (NTRS)
1985-01-01
Official portrait of Astronaut Anna L. Fisher. Fisher is posing with her helmet on the table in front of her and the American flag appears over the opposite shoulder (34357); Posing with an empty table in front of her and the American flag behind her (34358).
14 CFR 121.535 - Responsibility for operational control: Flag operations.
Code of Federal Regulations, 2013 CFR
2013-01-01
... dispatcher are jointly responsible for the preflight planning, delay, and dispatch release of a flight in... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Flight Operations...— (1) Monitoring the progress of each flight; (2) Issuing necessary instructions and information for...
14 CFR 121.535 - Responsibility for operational control: Flag operations.
Code of Federal Regulations, 2011 CFR
2011-01-01
... dispatcher are jointly responsible for the preflight planning, delay, and dispatch release of a flight in... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Flight Operations...— (1) Monitoring the progress of each flight; (2) Issuing necessary instructions and information for...
14 CFR 121.535 - Responsibility for operational control: Flag operations.
Code of Federal Regulations, 2010 CFR
2010-01-01
... dispatcher are jointly responsible for the preflight planning, delay, and dispatch release of a flight in... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Flight Operations...— (1) Monitoring the progress of each flight; (2) Issuing necessary instructions and information for...
14 CFR 121.535 - Responsibility for operational control: Flag operations.
Code of Federal Regulations, 2012 CFR
2012-01-01
... dispatcher are jointly responsible for the preflight planning, delay, and dispatch release of a flight in... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Flight Operations...— (1) Monitoring the progress of each flight; (2) Issuing necessary instructions and information for...
14 CFR 121.535 - Responsibility for operational control: Flag operations.
Code of Federal Regulations, 2014 CFR
2014-01-01
... dispatcher are jointly responsible for the preflight planning, delay, and dispatch release of a flight in... AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Flight Operations...— (1) Monitoring the progress of each flight; (2) Issuing necessary instructions and information for...
The Savannah River Site`s groundwater monitoring program. Third quarter 1990
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1991-05-06
The Environmental Protection Department/Environmental Monitoring Section (EPD/EMS) administers the Savannah River Site`s (SRS) Groundwater Monitoring Program. During third quarter 1990 (July through September) EPD/EMS conducted routine sampling of monitoring wells and drinking water locations. EPD/EMS established two sets of flagging criteria in 1986 to assist in the management of sample results. The flagging criteria do not define contamination levels; instead they aid personnel in sample scheduling, interpretation of data, and trend identification. The flagging criteria are based on detection limits, background levels in SRS groundwater, and drinking water standards. All analytical results from third quarter 1990 are listed in thismore » report, which is distributed to all site custodians. One or more analytes exceeded Flag 2 in 87 monitoring well series. Analytes exceeded Flat 2 for the first since 1984 in 14 monitoring well series. In addition to groundwater monitoring, EPD/EMS collected drinking water samples from SRS drinking water systems supplied by wells. The drinking water samples were analyzed for radioactive constituents.« less
The Savannah River Site's groundwater monitoring program
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1991-05-06
The Environmental Protection Department/Environmental Monitoring Section (EPD/EMS) administers the Savannah River Site's (SRS) Groundwater Monitoring Program. During third quarter 1990 (July through September) EPD/EMS conducted routine sampling of monitoring wells and drinking water locations. EPD/EMS established two sets of flagging criteria in 1986 to assist in the management of sample results. The flagging criteria do not define contamination levels; instead they aid personnel in sample scheduling, interpretation of data, and trend identification. The flagging criteria are based on detection limits, background levels in SRS groundwater, and drinking water standards. All analytical results from third quarter 1990 are listed in thismore » report, which is distributed to all site custodians. One or more analytes exceeded Flag 2 in 87 monitoring well series. Analytes exceeded Flat 2 for the first since 1984 in 14 monitoring well series. In addition to groundwater monitoring, EPD/EMS collected drinking water samples from SRS drinking water systems supplied by wells. The drinking water samples were analyzed for radioactive constituents.« less
[Efficient genome editing in human pluripotent stem cells through CRISPR/Cas9].
Liu, Gai-gai; Li, Shuang; Wei, Yu-da; Zhang, Yong-xian; Ding, Qiu-rong
2015-11-01
The RNA-guided CRISPR (clustered regularly interspaced short palindromic repeat)-associated Cas9 nuclease has offered a new platform for genome editing with high efficiency. Here, we report the use of CRISPR/Cas9 technology to target a specific genomic region in human pluripotent stem cells. We show that CRISPR/Cas9 can be used to disrupt a gene by introducing frameshift mutations to gene coding region; to knock in specific sequences (e.g. FLAG tag DNA sequence) to targeted genomic locus via homology directed repair; to induce large genomic deletion through dual-guide multiplex. Our results demonstrate the versatile application of CRISPR/Cas9 in stem cell genome editing, which can be widely utilized for functional studies of genes or genome loci in human pluripotent stem cells.
Activities commemorating John B. Herrington as first Native American astronaut
NASA Technical Reports Server (NTRS)
2002-01-01
KENNEDY SPACE CENTER, FLA. -- Seminole Native American Veterans serve as color guard during a pre-launch Native American ceremony at the Rocket Garden in the KSC Visitor Complex. David Nunez, U.S. Navy, carries the State of Florida Flag; David Stephen Bowers, U.S. Army, carries the Flag of the United States of America; Charles Billie Hiers, U.S. Marine Corps., carries the Seminole Tribe of Florida Flag. The ceremony was part of several days' activities commemorating John B. Herrington as the first tribally enrolled Native American astronaut to fly on a Shuttle mission. Herrington is a Mission Specialist on STS-113.
2015-01-01
ABSTRACT Physiotherapists use red flags to screen for serious pathology. Paediatric osteosarcoma is a rare disease, occurring predominantly in the area of the knee and shoulder, and it is not always included by physiotherapists on a differential diagnosis list. Traditional red flags do not always correspond to the initial signs and symptoms of osteosarcoma. Physiotherapists should routinely palpate along the length of the bone to detect a potential mass. The detection of a mass or symptoms that do not follow the expected course indicates the need for reassessment and possibly referral for further investigation. PMID:27504036
2007-01-17
KENNEDY SPACE CENTER, FLA. -- On platforms suspended from the top of the 525-foot-high VAB, workers use rollers and brushes to repaint the U.S. flag on the southwest side of the Vehicle Assembly Building. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo is also being painted. Known as the "meatball," the logo measures 110 feet by 132 feet, or about 12,300 square feet. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. Photo credit: NASA/George Shelton
2007-01-17
KENNEDY SPACE CENTER, FLA. -- On platforms suspended from the top of the 525-foot-high VAB, workers use rollers and brushes to repaint the U.S. flag on the southwest side of the Vehicle Assembly Building. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo is also being painted. Known as the "meatball," the logo measures 110 feet by 132 feet, or about 12,300 square feet. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. Photo credit: NASA/George Shelton
2011-01-13
CAPE CANAVERAL, Fla. -- In accordance with a Presidential Proclamation, the American Flag in the Launch Complex 39 area of NASA's Kennedy Space Center in Florida flies at half-staff to honor U.S. Rep. Gabrielle Giffords and others who were wounded or killed during a shooting spree in Tucson, Arizona. This flag and all American Flags at U.S. military and government installations across the country and abroad will remain at half-staff until sunset on Jan. 14. Giffords is the wife of NASA astronaut Mark Kelly, who is scheduled to command space shuttle Endeavour's last mission, STS-134, to the International Space Station later this year. Photo credit: NASA/Frankie Martin
2011-01-13
CAPE CANAVERAL, Fla. -- In accordance with a Presidential Proclamation, the American Flag in the Launch Complex 39 area of NASA's Kennedy Space Center in Florida flies at half-staff to honor U.S. Rep. Gabrielle Giffords and others who were wounded or killed during a shooting spree in Tucson, Arizona. This flag and all American Flags at U.S. military and government installations across the country and abroad will remain at half-staff until sunset on Jan. 14. Giffords is the wife of NASA astronaut Mark Kelly, who is scheduled to command space shuttle Endeavour's last mission, STS-134, to the International Space Station later this year. Photo credit: NASA/Frankie Martin
2011-01-13
CAPE CANAVERAL, Fla. -- In accordance with a Presidential Proclamation, the American Flag in the Launch Complex 39 area of NASA's Kennedy Space Center in Florida flies at half-staff to honor U.S. Rep. Gabrielle Giffords and others who were wounded or killed during a shooting spree in Tucson, Arizona. This flag and all American Flags at U.S. military and government installations across the country and abroad will remain at half-staff until sunset on Jan. 14. Giffords is the wife of NASA astronaut Mark Kelly, who is scheduled to command space shuttle Endeavour's last mission, STS-134, to the International Space Station later this year. Photo credit: NASA/Frankie Martin
2007-01-17
KENNEDY SPACE CENTER, FLA. -- On platforms suspended from the top of the 525-foot-high VAB, workers use rollers and brushes to repaint the U.S. flag on the southwest side of the Vehicle Assembly Building. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo is also being painted. Known as the "meatball," the logo measures 110 feet by 132 feet, or about 12,300 square feet. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. Photo credit: NASA/George Shelton
2007-01-09
KENNEDY SPACE CENTER, FLA. -- Painters' platforms are seen hanging on the side of Kennedy Space Center's 525-foot-high Vehicle Assembly Building to facilitate the repainting of the American flag and the NASA logo. Workers use rollers and brushes to do the painting. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23,437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. Photo credit: NASA/Kim Shiflett
2007-01-09
KENNEDY SPACE CENTER, FLA. -- Painters' platforms are seen hanging on the side of Kennedy Space Center's 525-foot-high Vehicle Assembly Building to facilitate the repainting of the American flag. The NASA logo is also being repainted. Workers use rollers and brushes to do the painting. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23,437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. Photo credit: NASA/Kim Shiflett
2007-01-17
KENNEDY SPACE CENTER, FLA. -- On platforms suspended from the top of the 525-foot-high VAB, workers use rollers and brushes to repaint the NASA logo on the southeast side of the Vehicle Assembly Building. Known as the "meatball," the logo measures 110 feet by 132 feet, or about 12,300 square feet. The U.S. flag is also being repainted. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. Photo credit: NASA/George Shelton
Case report: an electrocardiogram of spontaneous pneumothorax mimicking arm lead reversal.
Wieters, J Scott; Carlin, Joseph P; Morris, Andrew
2014-05-01
There are several previously documented findings for electrocardiograms (ECGs) of spontaneous pneumothorax. These findings include axis deviation, T-wave inversion, and right bundle branch block. When an ECG has the arm leads incorrectly placed, the ECG will display right axis deviation and inversion of the P waves in lead I. There have been no previously published ECGs of spontaneous pneumothorax that have shown the same findings as reversal of the limb leads of an ECG. A possible finding of spontaneous pneumothorax is an identical finding to that of an ECG that has been flagged for limb lead reversal. A patient presented in the emergency setting with acute chest pain and shortness of breath caused by a tension pneumothorax. An ECG was administered; findings indicated reversal of the arm leads (right axis deviation and inverted P waves in lead I), but there was no actual limb lead reversal present. ECG findings resolved upon resolution of the pneumothorax. If a patient presents with chest pain and shortness of breath, and the patient's ECG is flagged for limb lead reversal despite being set up correctly, the physician should raise clinical suspicion for a possible spontaneous pneumothorax. Copyright © 2014 Elsevier Inc. All rights reserved.
What causes flag smut of wheat?
USDA-ARS?s Scientific Manuscript database
The causal agent of flag smut of wheat is currently subject to strict quarantine regulations in many countries and is believed to have a wide host range on wild and cultivated grasses. This fungus has been classified as both Urocystis agropyri and Urocystis tritici. Urocystis agropyri was first desc...
78 FR 63233 - National Offshore Safety Advisory Committee; Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-23
... Equipment in Hazardous Areas on Foreign Flag Mobile Offshore Drilling Units. (4) Safety Impact of Liftboat... Equipment in Hazardous Areas on Foreign Flag Mobile Offshore Drilling Units (MODUs); (d) Safety Impact of... DEPARTMENT OF HOMELAND SECURITY Coast Guard [Docket No. USCG-2013-0886] National Offshore Safety...
Fermilab Today Tuesday, March 5, 2013 spacer Subscribe | Contact Us | Archive | Classifieds | Guidelines | Help Search GO spacer Calendar Have a safe day! Tuesday, March 5 3:30 p.m. DIRECTOR'S COFFEE Current Flag Status Flags at full staff Wilson Hall Cafe Tuesday, March 5 - Breakfast: All-American
China Report RED FLAG No 10, 16 MAY 1986
1986-07-03
4U Create a New Situation in Building the Legal System for Science and Technology in Our Country (pp 26-29) (Wu Mingyu ) The New Technological...Beijing RED FLAG in Chinese No 10, 16 May 86 pp 26-29 [Article by Wu Mingyu [0702 2494 3842
ERIC Educational Resources Information Center
Angel, Kenny; Sutton, Nancy
This paper describes six Ultimate Flag Games which offer a change from traditional games and sports that are usually geared toward athletically inclined students. These new games, aimed at middle school through college students, allow for success from the least-skilled through the most athletically talented students. Players are ability grouped…
75 FR 52722 - Taking and Importing of Marine Mammals
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-27
... International Dolphin Conservation Program (IDCP) by Spanish flag purse seine vessels or purse seine vessels operating under Spanish jurisdiction to be imported into the United States. The affirmative finding was... ETP by Spanish- flag purse seine vessels or purse seine vessels operating under Spanish jurisdiction...
33 CFR 334.850 - Lake Erie, west end, north of Erie Ordnance Depot, Lacarne, Ohio.
Code of Federal Regulations, 2010 CFR
2010-07-01
... firing into Area I, red flags will be flown from the safety tower at Camp Perry, and from flag poles in... fish will be discharged into the waters of the areas. (i) The regulations in this section shall be...
Race Discourse and the US Confederate Flag
ERIC Educational Resources Information Center
Holyfield, Lori; Moltz, Matthew Ryan; Bradley, Mindy S.
2009-01-01
Research reveals that racial hierarchies and "color-blind" racism is maintained through discourse. The current study utilizes exploratory data from focus groups in a predominantly white southern university in the United States to examine race talk, the Confederate Flag, and the construction of southern white identity. Drawing from…
14 CFR 121.687 - Dispatch release: Flag and domestic operations.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Dispatch release: Flag and domestic operations. 121.687 Section 121.687 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...) The dispatch release must contain, or have attached to it, weather reports, available weather...
14 CFR 121.687 - Dispatch release: Flag and domestic operations.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Dispatch release: Flag and domestic operations. 121.687 Section 121.687 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...) The dispatch release must contain, or have attached to it, weather reports, available weather...
14 CFR 121.687 - Dispatch release: Flag and domestic operations.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Dispatch release: Flag and domestic operations. 121.687 Section 121.687 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...) The dispatch release must contain, or have attached to it, weather reports, available weather...
14 CFR 121.687 - Dispatch release: Flag and domestic operations.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Dispatch release: Flag and domestic operations. 121.687 Section 121.687 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...) The dispatch release must contain, or have attached to it, weather reports, available weather...
14 CFR 121.687 - Dispatch release: Flag and domestic operations.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Dispatch release: Flag and domestic operations. 121.687 Section 121.687 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF...) The dispatch release must contain, or have attached to it, weather reports, available weather...
46 CFR 154.24 - Foreign flag vessel: IMO Certificate.
Code of Federal Regulations, 2011 CFR
2011-10-01
....24 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.24 Foreign flag... Construction and Equipment of Ships Carrying Liquefied Gases in Bulk, 1975” is usually sufficient evidence of...
46 CFR 154.24 - Foreign flag vessel: IMO Certificate.
Code of Federal Regulations, 2013 CFR
2013-10-01
....24 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.24 Foreign flag... Construction and Equipment of Ships Carrying Liquefied Gases in Bulk, 1975” is usually sufficient evidence of...
46 CFR 154.24 - Foreign flag vessel: IMO Certificate.
Code of Federal Regulations, 2012 CFR
2012-10-01
....24 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.24 Foreign flag... Construction and Equipment of Ships Carrying Liquefied Gases in Bulk, 1975” is usually sufficient evidence of...
46 CFR 154.24 - Foreign flag vessel: IMO Certificate.
Code of Federal Regulations, 2014 CFR
2014-10-01
....24 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.24 Foreign flag... Construction and Equipment of Ships Carrying Liquefied Gases in Bulk, 1975” is usually sufficient evidence of...
46 CFR 154.24 - Foreign flag vessel: IMO Certificate.
Code of Federal Regulations, 2010 CFR
2010-10-01
....24 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.24 Foreign flag... Construction and Equipment of Ships Carrying Liquefied Gases in Bulk, 1975” is usually sufficient evidence of...
The Full Kostant-Toda Hierarchy on the Positive Flag Variety
NASA Astrophysics Data System (ADS)
Kodama, Yuji; Williams, Lauren
2015-04-01
We study some geometric and combinatorial aspects of the solution to the full Kostant-Toda (f-KT) hierarchy, when the initial data is given by an arbitrary point on the totally non-negative (tnn) flag variety of . The f-KT flows on the tnn flag variety are complete, and we show that their asymptotics are completely determined by the cell decomposition of the tnn flag variety given by Rietsch (Total positivity and real flag varieties. Ph.D. Thesis, Massachusetts Institute of Technology, Cambridge, 1998). Our results represent the first results on the asymptotics of the f-KT hierarchy (and even the f-KT lattice); moreover, our results are not confined to the generic flow, but cover non-generic flows as well. We define the f-KT flow on the weight space via the moment map, and show that the closure of each f-KT flow forms an interesting convex polytope which we call a Bruhat interval polytope. In particular, the Bruhat interval polytope for the generic flow is the permutohedron of the symmetric group . We also prove analogous results for the full symmetric Toda hierarchy, by mapping our f-KT solutions to those of the full symmetric Toda hierarchy. In the appendix we show that Bruhat interval polytopes are generalized permutohedra, in the sense of Postnikov (Int. Math. Res. Not. IMRN (6):1026-1106, 2009).
Prescription Opioid Abuse and Dependence: Assessment Strategies for Counselors
ERIC Educational Resources Information Center
Weigel, Daniel J.; Donovan, Kimberly A.; Krug, Kevin S.; Dixon, Wayne A.
2007-01-01
The authors review the article "Prescription Drug Use and Abuse: Risk Factors, Red Flags, and Prevention Strategies" (J. H. Isaacson, J. A. Hopper, D. P. Alford, & T. Parran, 2005), which provides an overview of the recent increase in prescription opioid abuse and dependence from the physician's perspective. In the present article, the authors…
East Europe Report, Political, Sociological and Military Affairs.
1983-11-10
34Dialektyka i historia " [Dialectics and History], Lenin was the only one of Marx’s successors to undertake an open dialectic with "Das Kapital" and to...Milan Veres, Yugoslav ambassador in Budapest , and presented him the Order of Flag of the Hungarian People’s Republic. [Text] [AU231531 Belgrade
An unusual case of seed dispersal in an invasive aquatic; yellow flag iris (Iris pseudacorus)
USDA-ARS?s Scientific Manuscript database
Understanding reproductive mode of invasive plants can help managers plan more efficacious control. Invasive aquatics typically reproduce primarily through vegetative means. Yellow flag iris is an invasive plant species often growing as an emergent aquatic. There have been contradictory reports of i...
78 FR 16475 - Procurement List; Proposed Additions and Deletion
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-15
... Activity: Military Resale-Defense Commissary Agency (DeCA), Fort Lee, VA Coverage: C-List for the requirements of military commissaries and exchanges as aggregated by the Defense Commissary Agency. NSN: 7510-01-389-2262--Self Stick Rectangular Flag, ``Sign Here'', 1.0'' X 1.75'', Yellow Flags NPA...
La Estrella Perdida (The Missing Star).
ERIC Educational Resources Information Center
Cohen, Allen Stephen
This story in Spanish and English is written for elementary school children in grades 1-5. The main character of the story is a star that is part of the Puerto Rican flag. The star leaves the flag and goes on a journey that is illustrated with pen-and-ink drawings. (Author/NCR)
Modifying Flag Football for Gender Equitable Engagement in Secondary Schools
ERIC Educational Resources Information Center
Kahan, David
2008-01-01
Flag or touch football is a popular activity unit in American secondary physical education curricula. However, unlike other sports its stigmatization as a masculine-typed activity and frequent inequitable distribution of game play opportunities at the skill positions (e.g., receiver, quarterback) results in the marginalization of female…
FMRI of visual working memory in high school football players.
Shenk, Trey E; Robinson, Meghan E; Svaldi, Diana O; Abbas, Kausar; Breedlove, Katherine M; Leverenz, Larry J; Nauman, Eric A; Talavage, Thomas M
2015-01-01
Visual working memory deficits have been observed in at-risk athletes. This study uses a visual N-back working memory functional magnetic resonance imaging task to longitudinally assess asymptomatic football athletes for abnormal activity. Athletes were increasingly "flagged" as the season progressed. Flagging may provide early detection of injury.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 10 Energy 4 2010-01-01 2010-01-01 false Purpose. 1002.1 Section 1002.1 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) OFFICIAL SEAL AND DISTINGUISHING FLAG General § 1002.1 Purpose. The purpose of this part is to describe the official seal and distinguishing flag of the Department of Energy, and to...
14 CFR 1221.106 - Establishment of the NASA Flag.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Establishment of the NASA Flag. 1221.106 Section 1221.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA...
14 CFR 1221.106 - Establishment of the NASA Flag.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Establishment of the NASA Flag. 1221.106 Section 1221.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA...
14 CFR 1221.106 - Establishment of the NASA Flag.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Establishment of the NASA Flag. 1221.106 Section 1221.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA...
14 CFR 1221.106 - Establishment of the NASA Flag.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Establishment of the NASA Flag. 1221.106 Section 1221.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA...
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Flight attendant duty period limitations and rest requirements: Domestic, flag, and supplemental operations. 121.467 Section 121.467 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS...
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Flight attendant duty period limitations and rest requirements: Domestic, flag, and supplemental operations. 121.467 Section 121.467 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS...
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Flight attendant duty period limitations and rest requirements: Domestic, flag, and supplemental operations. 121.467 Section 121.467 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS...
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Flight attendant duty period limitations and rest requirements: Domestic, flag, and supplemental operations. 121.467 Section 121.467 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS...
Federal Register 2010, 2011, 2012, 2013, 2014
2011-01-11
... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2010-0111] Stakeholder Meetings Regarding the U.S.-Flag Great Lakes Fleet Revitalization Study; Correction AGENCY: Maritime Administration, Department of Transportation. ACTION: Correction Notice. SUMMARY: On December 29, 2010, at 75 FR...
76 FR 20080 - Inventory of U.S.-Flag Launch Barges
Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-11
... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD 2011 0030] Inventory of...: Inventory of U.S.-Flag Launch Barges. SUMMARY: The Maritime Administration is updating its inventory of U.S..._program/Launch_Barge_Program.htm . DATES: Any comments on this inventory should be submitted in writing to...
77 FR 50086 - Taking and Importing of Marine Mammals
Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-20
... International Dolphin Conservation Program (IDCP) by Spanish-flag purse seine vessels or purse seine vessels operating under Spanish jurisdiction to be imported into the United States. The affirmative finding was... derived from yellowfin tuna harvested in the ETP by Spanish-flag purse seine vessels or purse seine...
76 FR 52319 - Taking and Importing of Marine Mammals
Federal Register 2010, 2011, 2012, 2013, 2014
2011-08-22
... International Dolphin Conservation Program (IDCP) by Spanish-flag purse seine vessels or purse seine vessels operating under Spanish jurisdiction to be imported into the United States. The affirmative finding was... States of yellowfin tuna and products derived from yellowfin tuna harvested in the ETP by Spanish-flag...
Code of Federal Regulations, 2013 CFR
2013-10-01
... to, the use of flagging, bright eyes, tacks, and paint), cutting, and/or removal of trees or.... We prohibit hunters field dressing deer within 100 feet (30 m) of a road or trail. 22. We prohibit... to, the use of flagging, bright eyes, tacks, and paint), cutting, and/or removal of trees or...
Code of Federal Regulations, 2014 CFR
2014-10-01
... to, the use of flagging, bright eyes, tacks, and paint), cutting, and/or removal of trees or.... We prohibit hunters field dressing deer within 100 feet (30 m) of a road or trail. 22. We prohibit... to, the use of flagging, bright eyes, tacks, and paint), cutting, and/or removal of trees or...
Code of Federal Regulations, 2012 CFR
2012-10-01
... to, the use of flagging, bright eyes, tacks, and paint), cutting, and/or removal of trees or.... We prohibit hunters field dressing deer within 100 feet (30 m) of a road or trail. 22. We prohibit... to, the use of flagging, bright eyes, tacks, and paint), cutting, and/or removal of trees or...
48 CFR 47.405 - Contract clause.
Code of Federal Regulations, 2010 CFR
2010-10-01
... TRANSPORTATION Air Transportation by U.S.-Flag Carriers 47.405 Contract clause. The contracting officer shall insert the clause at 52.247-63, “Preference for U.S.-Flag Air Carriers, in solicitations and contracts whenever it is possible that U.S. Government-financed international air transportation of personnel (and...
Code of Federal Regulations, 2011 CFR
2011-10-01
... of bulk liquid cargoes such as liquid petroleum products, vegetable oils, and molasses. U.S.-flag... cargoes of dry bulk items or, when carried in deep tanks, bulk liquids such as petroleum and vegetable oils. Foreign-flag vessel means any vessel of foreign registry including vessels owned by U.S. citizens...
Code of Federal Regulations, 2010 CFR
2010-10-01
... of bulk liquid cargoes such as liquid petroleum products, vegetable oils, and molasses. U.S.-flag... cargoes of dry bulk items or, when carried in deep tanks, bulk liquids such as petroleum and vegetable oils. Foreign-flag vessel means any vessel of foreign registry including vessels owned by U.S. citizens...
The Impact of Flagging on the Admission Process.
ERIC Educational Resources Information Center
Cahalan-Laitusis, Cara; Mandinach, Ellen B.; Camara, Wayne J.
2003-01-01
Study explored issues surrounding flagging test scores taken under non-standard conditions and how the admission process could better serve students with disabilities. Respondents to survey felt current system was not adequately serving subgroups of students, believing some non-disabled students were manipulating the system to gain an advantage on…
75 FR 66125 - Federal Land Managers' Air Quality Related Values Work Group (FLAG)
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-27
... DEPARTMENT OF THE INTERIOR National Park Service Federal Land Managers' Air Quality Related Values... Public Comments document. The Federal Land Managers' Air Quality Related Values Work Group (FLAG) was... (the Agencies), to evaluate air pollution effects on their air quality related values (AQRVs); and (2...
46 CFR 154.15 - U.S. flag vessel: Endorsement application.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 5 2014-10-01 2014-10-01 false U.S. flag vessel: Endorsement application. 154.15 Section 154.15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.15 U.S...
46 CFR 153.16 - Requirements for foreign flag vessel permits.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 5 2012-10-01 2012-10-01 false Requirements for foreign flag vessel permits. 153.16 Section 153.16 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS General § 153.16...
46 CFR 154.15 - U.S. flag vessel: Endorsement application.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 5 2010-10-01 2010-10-01 false U.S. flag vessel: Endorsement application. 154.15 Section 154.15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.15 U.S...
46 CFR 154.15 - U.S. flag vessel: Endorsement application.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 5 2011-10-01 2011-10-01 false U.S. flag vessel: Endorsement application. 154.15 Section 154.15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.15 U.S...
46 CFR 153.16 - Requirements for foreign flag vessel permits.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 5 2011-10-01 2011-10-01 false Requirements for foreign flag vessel permits. 153.16 Section 153.16 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS General § 153.16...
46 CFR 154.15 - U.S. flag vessel: Endorsement application.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 46 Shipping 5 2012-10-01 2012-10-01 false U.S. flag vessel: Endorsement application. 154.15 Section 154.15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.15 U.S...
46 CFR 154.15 - U.S. flag vessel: Endorsement application.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 5 2013-10-01 2013-10-01 false U.S. flag vessel: Endorsement application. 154.15 Section 154.15 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.15 U.S...
46 CFR 153.16 - Requirements for foreign flag vessel permits.
Code of Federal Regulations, 2013 CFR
2013-10-01
... 46 Shipping 5 2013-10-01 2013-10-01 false Requirements for foreign flag vessel permits. 153.16 Section 153.16 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS General § 153.16...
46 CFR 153.16 - Requirements for foreign flag vessel permits.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 5 2010-10-01 2010-10-01 false Requirements for foreign flag vessel permits. 153.16 Section 153.16 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS General § 153.16...
46 CFR 153.16 - Requirements for foreign flag vessel permits.
Code of Federal Regulations, 2014 CFR
2014-10-01
... 46 Shipping 5 2014-10-01 2014-10-01 false Requirements for foreign flag vessel permits. 153.16 Section 153.16 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING BULK LIQUID, LIQUEFIED GAS, OR COMPRESSED GAS HAZARDOUS MATERIALS General § 153.16...
NASA Astrophysics Data System (ADS)
Noku, Shadrach K.; Espi, Joseph O.; Matsueda, Hiroharu
2015-01-01
We present the first sulfur (S) isotope data of sulfides, sulfates, pyrite in host mudstone, and bulk sulfur of gabbroic rocks from the Laloki and Federal Flag massive Cu-Zn-Au-Ag deposits in the Astrolabe mineral district, Papua New Guinea. Early-stage pyrite-marcasite, chalcopyrite, and sphalerite from Laloki display wide range of δ34S values from -4.5 to +7.0 ‰ ( n = 16). Late-stage pyrite, chalcopyrite, and sphalerite have restricted δ34S values of -1.9 to +4.7 ‰ ( n = 16). The mineralizing stage these correspond to had moderately saline (5.9-8.4 NaCl eq. wt%) mineralizing fluids of possible magmatic origin. A single analysis of late-stage barite has a value of δ34S +17.9 ‰, which is likely similar to coexisting seawater sulfate. Pyrite from the foot-wall mudstone at Laloki has very light δ34S values of -36.1 to -33.8 ‰ ( n = 2), which suggest an organic source for S. Pyrite-marcasite and chalcopyrite from Federal Flag show δ34S values of -2.4 to -1.9 ‰ ( n = 2), consistent with a magmatic origin, either leached from intrusive magmatic rocks or derived from magmatic-hydrothermal fluids. The very narrow range and near-zero δ34S values (-1.0 to +0.6 ‰) of bulk gabbroic samples is consistent with mantle-derived magmatic S. Sulfur isotope characteristics of sulfides and sulfates are, however, very similar to base metal sulfide accumulations associated with modern volcanic arcs and sedimented mid-ocean ridges. The most reasonable interpretation is that the range of the sulfide and sulfate δ34S values from both Laloki and Federal Flag massive sulfide deposits is indicative of the complex interaction of magmatic fluids, seawater, gabbroic rocks, and mudstone.
Algorithm Updates for the Fourth SeaWiFS Data Reprocessing
NASA Technical Reports Server (NTRS)
Hooker, Stanford, B. (Editor); Firestone, Elaine R. (Editor); Patt, Frederick S.; Barnes, Robert A.; Eplee, Robert E., Jr.; Franz, Bryan A.; Robinson, Wayne D.; Feldman, Gene Carl; Bailey, Sean W.
2003-01-01
The efforts to improve the data quality for the Sea-viewing Wide Field-of-view Sensor (SeaWiFS) data products have continued, following the third reprocessing of the global data set in May 2000. Analyses have been ongoing to address all aspects of the processing algorithms, particularly the calibration methodologies, atmospheric correction, and data flagging and masking. All proposed changes were subjected to rigorous testing, evaluation and validation. The results of these activities culminated in the fourth reprocessing, which was completed in July 2002. The algorithm changes, which were implemented for this reprocessing, are described in the chapters of this volume. Chapter 1 presents an overview of the activities leading up to the fourth reprocessing, and summarizes the effects of the changes. Chapter 2 describes the modifications to the on-orbit calibration, specifically the focal plane temperature correction and the temporal dependence. Chapter 3 describes the changes to the vicarious calibration, including the stray light correction to the Marine Optical Buoy (MOBY) data and improved data screening procedures. Chapter 4 describes improvements to the near-infrared (NIR) band correction algorithm. Chapter 5 describes changes to the atmospheric correction and the oceanic property retrieval algorithms, including out-of-band corrections, NIR noise reduction, and handling of unusual conditions. Chapter 6 describes various changes to the flags and masks, to increase the number of valid retrievals, improve the detection of the flag conditions, and add new flags. Chapter 7 describes modifications to the level-la and level-3 algorithms, to improve the navigation accuracy, correct certain types of spacecraft time anomalies, and correct a binning logic error. Chapter 8 describes the algorithm used to generate the SeaWiFS photosynthetically available radiation (PAR) product. Chapter 9 describes a coupled ocean-atmosphere model, which is used in one of the changes described in Chapter 4. Finally, Chapter 10 describes a comparison of results from the third and fourth reprocessings along the US. Northeast coast.
CNNs flag recognition preprocessing scheme based on gray scale stretching and local binary pattern
NASA Astrophysics Data System (ADS)
Gong, Qian; Qu, Zhiyi; Hao, Kun
2017-07-01
Flag is a rather special recognition target in image recognition because of its non-rigid features with the location, scale and rotation characteristics. The location change can be handled well by the depth learning algorithm Convolutional Neural Networks (CNNs), but the scale and rotation changes are quite a challenge for CNNs. Since it has good rotation and gray scale invariance, the local binary pattern (LBP) is combined with grayscale stretching and CNNs to make LBP and grayscale stretching as CNNs pretreatment, which can not only significantly improve the efficiency of flag recognition, but can also evaluate the recognition effect through ROC, accuracy, MSE and quality factor.
2007-01-04
KENNEDY SPACE CENTER, FLA. -- Elevated platforms are seen hanging on the side of Kennedy Space Center's Vehicle Assembly Building to facilitate the repainting of the American flag and NASA logo. Workers, suspended on the platforms from the top of the 525-foot-high VAB, use rollers and brushes to do the painting. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. Photo credit: NASA/George Shelton
2007-01-09
KENNEDY SPACE CENTER, FLA. -- Painters' scaffolding is seen hanging on the side of Kennedy Space Center's Vehicle Assembly Building to facilitate the repainting of the American flag. The NASA logo is also being repainted. Workers, suspended on platforms from the top of the 525-foot-high VAB, use rollers and brushes to do the painting. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23,437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. Photo credit: NASA/Kim Shiflett
2007-01-09
KENNEDY SPACE CENTER, FLA. -- Painters' scaffolding is seen hanging on the side of Kennedy Space Center's Vehicle Assembly Building to facilitate the repainting of the American flag and the NASA logo. Workers, suspended on platforms from the top of the 525-foot-high VAB, use rollers and brushes to do the painting. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23,437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. Photo credit: NASA/Kim Shiflett
2007-01-09
KENNEDY SPACE CENTER, FLA. -- Painters' scaffolding is seen hanging on the side of Kennedy Space Center's Vehicle Assembly Building to facilitate the repainting of the NASA logo. The American flag is also being repainted. Workers, suspended on platforms from the top of the 525-foot-high VAB, use rollers and brushes to do the painting. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23,437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. Photo credit: NASA/Kim Shiflett
2007-01-04
KENNEDY SPACE CENTER, FLA. -- Elevated platforms are seen hanging on the side of Kennedy Space Center's Vehicle Assembly Building to facilitate the repainting of the American flag and NASA logo. Workers, suspended on the platforms from the top of the 525-foot-high VAB, use rollers and brushes to do the painting. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet. Photo credit: NASA/George Shelton
Workers painting the Flag and Meatball on the VAB
2007-01-03
Elevated platforms are seen hanging on the side of Kennedy Space Center's Vehicle Assembly Building in a view looking across from the turn basin. To the right is the large external tank barge. Workers, suspended on the platforms from the top of the 525-foot-high VAB, use rollers and brushes to do the painting. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet.
Soccer; Speedball; Flag Football, June 1976--June 1978. NAGWS Guide.
ERIC Educational Resources Information Center
Messing, Anne, Ed.; And Others
This guide for soccer, speedball, and flag football is one in a series of guides for 22 sports published by the National Association for Girls and Women in Sport (NAGWS). Guides contain information on NAGWS-approved playing rules, officials' ratings, articles on teaching, coaching and organization, rules governing national championships,…
Defense.gov Special Report: Travels with Carter - May 2013
Germany Germany Flag of Djibouti Djibouti Flag of Afghanistan Afghanistan Top Stories Carter Wraps Up , Civilians Breedlove Takes Charge at European Command Carter Arrives in Germany for Eucom Change of Command Meetings Carter Attends Eucom Change of Command Ceremony in Stuttgart, Germany Travel Locations Travel
Tips to Increase Girls' Participation in Flag Football Units
ERIC Educational Resources Information Center
Hannon, James C.; Ratliffe, Thomas
2006-01-01
Despite the apparent popularity of flag football as an activity in physical education class and football as an after-school offering for girls, studies related to gender stereotyping of sports have found overwhelming evidence indicating that football is perceived as a masculine activity among males and females in primary school, secondary school,…
Chemical Sciences and Engineering - US China Electric Vehicle and Battery
Technology Workshop Argonne National Laboratory Chemical Sciences & Engineering DOE Logo Photo Gallery Hotels Maps Bus Schedule Contact Us TCS Building and Conference Center, Argonne National Lab TCS Building and Conference Center United States Flag China flag 2011 U.S.-China Electric Vehicle
22 CFR 228.22 - Air transportation.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Air transportation. 228.22 Section 228.22... for USAID Financing § 228.22 Air transportation. (a) The eligibility of air transportation is determined by the flag registry of the aircraft. The term “U.S. flag air carrier” means one of a class of air...
14 CFR 1221.113 - Use of the NASA Flags.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Use of the NASA Flags. 1221.113 Section 1221.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA Program...
14 CFR 1221.113 - Use of the NASA Flags.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Use of the NASA Flags. 1221.113 Section 1221.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA Program...
14 CFR 1221.113 - Use of the NASA Flags.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Use of the NASA Flags. 1221.113 Section 1221.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA Program...
14 CFR 1221.113 - Use of the NASA Flags.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Use of the NASA Flags. 1221.113 Section 1221.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA Program...
Defense.gov Special Report: Travels With Hagel
. Flag of Mexico. Flag of Guatemala. April 2014 Defense Secretary Chuck Hagel began a three-day trip to troops who conduct military-to-military engagements in the region. He then visited Mexico City to attend the second U.S.-Canada-Mexico North American Defense Ministerial conference before heading to
49 CFR 214.521 - Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles.
Code of Federal Regulations, 2010 CFR
2010-10-01
... maintenance machines and hi-rail vehicles. 214.521 Section 214.521 Transportation Other Regulations Relating... WORKPLACE SAFETY On-Track Roadway Maintenance Machines and Hi-Rail Vehicles § 214.521 Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles. Each on-track roadway maintenance machine...
48 CFR 47.403-2 - Air transport agreements between the United States and foreign governments.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Air transport agreements....-Flag Carriers 47.403-2 Air transport agreements between the United States and foreign governments... attend, the use of a foreign-flag air carrier that provides transportation under an air transport...
14 CFR 121.551 - Restriction or suspension of operation: Domestic and flag operations.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Restriction or suspension of operation: Domestic and flag operations. 121.551 Section 121.551 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... conditions, that are a hazard to safe operations, it shall restrict or suspend operations until those...
14 CFR 121.551 - Restriction or suspension of operation: Domestic and flag operations.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Restriction or suspension of operation: Domestic and flag operations. 121.551 Section 121.551 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... conditions, that are a hazard to safe operations, it shall restrict or suspend operations until those...
38 CFR 1.10 - Eligibility for and disposition of the United States flag for burial purposes.
Code of Federal Regulations, 2010 CFR
2010-07-01
... separation from such service under conditions other than dishonorable, on or after April 25, 1951. (Authority... issued a flag on application signed by guardian). (iii) Parents, including adoptive, stepparents, and foster parents. (iv) Brothers or sisters, including brothers or sisters of the halfblood. (v) Uncles or...
Code of Federal Regulations, 2011 CFR
2011-10-01
... marking (this includes but is not limited to, the use of flagging, bright eyes, tacks, and paint), cutting... (this includes but is not limited to, the use of flagging, bright eyes, tacks, and paint), cutting, and..., Lily Lake, and the posted fishing areas along the south side of Parkertown Dock Road, North side of...
Code of Federal Regulations, 2011 CFR
2011-10-01
.... For purposes of this part only: (a) Commercial cargo means cargo other than military cargo and civilian preference cargo. (b) Military cargo means that cargo required to be carried on a U.S.-flag vessel... by law to be carried on a U.S.-flag vessel, including, but not limited to, cargo required to be...
14 CFR 121.615 - Dispatch or flight release over water: Flag and supplemental operations.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Dispatch or flight release over water: Flag and supplemental operations. 121.615 Section 121.615 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS OPERATING...
75 FR 51099 - Final Supplementary Rules for Public Land in Oregon and Washington
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-18
... must not operate a motorcycle or ATV/OHV without a safety flag on Peterson Road, Juniper Road, Smith Canyon Road, and/or Wilderness Road. Safety flags are not required for street-legal, four- wheeled... the public's health and safety. They provide needed guidance in the areas of special forest products...
Code of Federal Regulations, 2013 CFR
2013-01-01
.... III. Detecting Red Flags The Program's policies and procedures should address the detection of Red... detect relevant Red Flags that may arise in the performance of the service provider's activities, and... or creditor detects a fraud or active duty alert; (c) Implementing any requirements for furnishers of...
Code of Federal Regulations, 2014 CFR
2014-01-01
.... III. Detecting Red Flags The Program's policies and procedures should address the detection of Red... detect relevant Red Flags that may arise in the performance of the service provider's activities, and... or creditor detects a fraud or active duty alert; (c) Implementing any requirements for furnishers of...
Code of Federal Regulations, 2012 CFR
2012-01-01
.... III. Detecting Red Flags The Program's policies and procedures should address the detection of Red... detect relevant Red Flags that may arise in the performance of the service provider's activities, and... or creditor detects a fraud or active duty alert; (c) Implementing any requirements for furnishers of...
Code of Federal Regulations, 2012 CFR
2012-01-01
.... III. Detecting Red Flags The Program's policies and procedures should address the detection of Red... detect relevant Red Flags that may arise in the performance of the service provider's activities, and... or creditor detects a fraud or active duty alert; (c) Implementing any requirements for furnishers of...
Code of Federal Regulations, 2014 CFR
2014-01-01
.... III. Detecting Red Flags The Program's policies and procedures should address the detection of Red... detect relevant Red Flags that may arise in the performance of the service provider's activities, and... or creditor detects a fraud or active duty alert; (c) Implementing any requirements for furnishers of...
Code of Federal Regulations, 2011 CFR
2011-01-01
.... III. Detecting Red Flags The Program's policies and procedures should address the detection of Red... detect relevant Red Flags that may arise in the performance of the service provider's activities, and... or creditor detects a fraud or active duty alert; (c) Implementing any requirements for furnishers of...
Code of Federal Regulations, 2013 CFR
2013-01-01
.... III. Detecting Red Flags The Program's policies and procedures should address the detection of Red... detect relevant Red Flags that may arise in the performance of the service provider's activities, and... or creditor detects a fraud or active duty alert; (c) Implementing any requirements for furnishers of...
49 CFR 214.521 - Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 49 Transportation 4 2011-10-01 2011-10-01 false Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles. 214.521 Section 214.521 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD WORKPLACE SAFETY On-Track Roadway Maintenance...
49 CFR 214.521 - Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles.
Code of Federal Regulations, 2012 CFR
2012-10-01
... 49 Transportation 4 2012-10-01 2012-10-01 false Flagging equipment for on-track roadway maintenance machines and hi-rail vehicles. 214.521 Section 214.521 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD WORKPLACE SAFETY On-Track Roadway Maintenance...
15 CFR 970.801 - Criteria for safety of life and property at sea.
Code of Federal Regulations, 2010 CFR
2010-01-01
... REGULATIONS OF THE ENVIRONMENTAL DATA SERVICE DEEP SEABED MINING REGULATIONS FOR EXPLORATION LICENSES Safety... inspection statutes pertaining to United States flag vessels are: 46 U.S.C. 86 (Loadlines); 46 U.S.C. 395... hire). All United States flag vessels will be required to meet existing regulatory requirements...
46 CFR 382.2 - Data submission.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 46 Shipping 8 2010-10-01 2010-10-01 false Data submission. 382.2 Section 382.2 Shipping MARITIME... CARRIAGE OF BULK AND PACKAGED PREFERENCE CARGOES ON U.S.-FLAG COMMERCIAL VESSELS § 382.2 Data submission... shall be performed on the basis of cost data provided by the U.S.-flag vessel operator, as specified...
46 CFR 382.2 - Data submission.
Code of Federal Regulations, 2011 CFR
2011-10-01
... 46 Shipping 8 2011-10-01 2011-10-01 false Data submission. 382.2 Section 382.2 Shipping MARITIME... CARRIAGE OF BULK AND PACKAGED PREFERENCE CARGOES ON U.S.-FLAG COMMERCIAL VESSELS § 382.2 Data submission... shall be performed on the basis of cost data provided by the U.S.-flag vessel operator, as specified...
46 CFR 154.22 - Foreign flag vessel: Certificate of Compliance endorsement application.
Code of Federal Regulations, 2012 CFR
2012-10-01
... (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.22 Foreign flag vessel: Certificate of Compliance endorsement application. (a... vessel meets § 154.1725(a) (4), (5), and (7). (9) If the vessel is a new gas vessel, or an existing...
46 CFR 154.22 - Foreign flag vessel: Certificate of Compliance endorsement application.
Code of Federal Regulations, 2011 CFR
2011-10-01
... (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.22 Foreign flag vessel: Certificate of Compliance endorsement application. (a... vessel meets § 154.1725(a) (4), (5), and (7). (9) If the vessel is a new gas vessel, or an existing...
46 CFR 154.22 - Foreign flag vessel: Certificate of Compliance endorsement application.
Code of Federal Regulations, 2013 CFR
2013-10-01
... (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.22 Foreign flag vessel: Certificate of Compliance endorsement application. (a... certification that the vessel meets § 154.1725(a) (4), (5), and (7). (9) If the vessel is a new gas vessel, or...
46 CFR 154.22 - Foreign flag vessel: Certificate of Compliance endorsement application.
Code of Federal Regulations, 2014 CFR
2014-10-01
... (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SAFETY STANDARDS FOR SELF-PROPELLED VESSELS CARRYING BULK LIQUEFIED GASES General § 154.22 Foreign flag vessel: Certificate of Compliance endorsement application. (a... certification that the vessel meets § 154.1725(a) (4), (5), and (7). (9) If the vessel is a new gas vessel, or...
Baillie, Charles A; VanZandbergen, Christine; Tait, Gordon; Hanish, Asaf; Leas, Brian; French, Benjamin; Hanson, C William; Behta, Maryam; Umscheid, Craig A
2013-12-01
Identification of patients at high risk for readmission is a crucial step toward improving care and reducing readmissions. The adoption of electronic health records (EHR) may prove important to strategies designed to risk stratify patients and introduce targeted interventions. To develop and implement an automated prediction model integrated into our health system's EHR that identifies on admission patients at high risk for readmission within 30 days of discharge. Retrospective and prospective cohort. Healthcare system consisting of 3 hospitals. All adult patients admitted from August 2009 to September 2012. An automated readmission risk flag integrated into the EHR. Thirty-day all-cause and 7-day unplanned healthcare system readmissions. Using retrospective data, a single risk factor, ≥ 2 inpatient admissions in the past 12 months, was found to have the best balance of sensitivity (40%), positive predictive value (31%), and proportion of patients flagged (18%), with a C statistic of 0.62. Sensitivity (39%), positive predictive value (30%), proportion of patients flagged (18%), and C statistic (0.61) during the 12-month period after implementation of the risk flag were similar. There was no evidence for an effect of the intervention on 30-day all-cause and 7-day unplanned readmission rates in the 12-month period after implementation. An automated prediction model was effectively integrated into an existing EHR and identified patients on admission who were at risk for readmission within 30 days of discharge. © 2013 Society of Hospital Medicine.
Harahsheh, Ashraf S; O'Byrne, Michael L; Pastor, Bill; Graham, Dionne A; Fulton, David R
2017-11-01
We conducted a study to assess test characteristics of red-flag criteria for identifying cardiac disease causing chest pain and technical charges of low-probability referrals. Accuracy of red-flag criteria was ascertained through study of chest pain Standardized Clinical Assessment and Management Plans (SCAMPs®) data. Patients were divided into 2 groups: Group1 (concerning clinical elements) and Group2 (without). We compared incidence of cardiac disease causing chest pain between these 2 groups. Technical charges of Group 2 were analyzed using the Pediatric Health Information System database. Potential savings for the US population was estimated using National Ambulatory Medical Care Survey data. Fifty-two percent of subjects formed Group 1. Cardiac disease causing chest pain was identified in 8/1656 (0.48%). No heart disease was identified in patients in Group 2 ( P = .03). Applying red-flags in determining need for referral identified patients with cardiac disease causing chest pain with 100% sensitivity. Median technical charges for Group 2, over a 4-year period, were US2014$775 559. Eliminating cardiac testing of low-probability referrals would save US2014$3 775 182 in technical charges annually. Red-flag criteria were an effective screen for children with chest pain. Eliminating cardiac testing in children without red-flags for referral has significant technical charge savings.
Ways forward in quantifying data uncertainty in geological databases
NASA Astrophysics Data System (ADS)
Kint, Lars; Chademenos, Vasileios; De Mol, Robin; Kapel, Michel; Lagring, Ruth; Stafleu, Jan; van Heteren, Sytze; Van Lancker, Vera
2017-04-01
Issues of compatibility of geological data resulting from the merging of many different data sources and time periods may jeopardize harmonization of data products. Important progress has been made due to increasing data standardization, e.g., at a European scale through the SeaDataNet and Geo-Seas data management infrastructures. Common geological data standards are unambiguously defined, avoiding semantic overlap in geological data and associated metadata. Quality flagging is also applied increasingly, though ways in further propagating this information in data products is still at its infancy. For the Belgian and southern Netherlands part of the North Sea, databases are now rigorously re-analyzed in view of quantifying quality flags in terms of uncertainty to be propagated through a 3D voxel model of the subsurface (https://odnature.naturalsciences.be/tiles/). An approach is worked out to consistently account for differences in positioning, sampling gear, analysis procedures and vintage. The flag scaling is used in the interpolation process of geological data, but will also be used when visualizing the suitability of geological resources in a decision support system. Expert knowledge is systematically revisited as to avoid totally inappropriate use of the flag scaling process. The quality flagging is also important when communicating results to end-users. Therefore, an open data policy in combination with several processing tools will be at the heart of a new Belgian geological data portal as a platform for knowledge building (KB) and knowledge management (KM) serving the marine geoscience, the policy community and the public at large.
Shi, Sheng-Bo; Chen, Wen-Jie; Shi, Rui; Li, Miao; Zhang, Huai-Gang; Sun, Ya-Nan
2014-09-01
Taking four wheat varieties developed by Northwest Institute of Plateau Biology, Chinese Academy of Sciences, as test materials, with the measurement of content of photosynthetic pigments, leaf area, fresh and dry mass of flag leaf, the PS II photochemistry efficiency of abaxial and adaxial surface of flag leaf and its adaptation to strong solar radiation during the period of heading stage in Xiangride region were investigated with the pulse-modulated in-vivo chlorophyll fluorescence technique. The results indicated that flag leaf angle mainly grew in horizontal state in Gaoyuan 314, Gaoyuan 363 and Gaoyuan 584, and mainly in vertical state in Gaoyuan 913 because of its smaller leaf area and larger width. Photosynthetic pigments were different among the 4 varieties, and positively correlated with intrinsic PS II photochemistry efficiencies (Fv/Fm). In clear days, especially at noon, the photosynthetic photoinhibition was more serious in abaxial surface of flag leaf due to directly facing the solar radiation, but it could recover after reduction of sunlight intensity in the afternoon, which meant that no inactive damage happened in PS II reaction centers. There were significant differences of PS II actual and maximum photochemical efficiencies at the actinic light intensity (ΦPS II and Fv'/Fm') between abaxial and adaxial surface, and their relative variation trends were on the contrary. The photochemical and non-photochemical quenching coefficients (qP and NPQ) had a similar tendency in both abaxial and adaxial surfaces. Although ΦPS II and qP were lower in adaxial surface of flag leaf, the Fv'/Fm' was significantly higher, which indicated that the potential PS II capture efficiency of excited energy was higher. The results demonstrated that process of photochemical and non-photochemical quenching could effectively dissipate excited energy caused by strong solar radiation, and there were higher adaptation capacities in wheat varieties natively cultivated in Qinghai-Tibetan Plateau area.
Kong, Lingan; Wang, Fahong; Feng, Bo; Li, Shengdong; Si, Jisheng; Zhang, Bin
2010-07-11
In wheat (Triticum aestivum L), the flag leaf has been thought of as the main source of assimilates for grain growth, whereas the peduncle has commonly been thought of as a transporting organ. The photosynthetic characteristics of the exposed peduncle have therefore been neglected. In this study, we investigated the anatomical traits of the exposed peduncle during wheat grain ontogenesis, and we compared the exposed peduncle to the flag leaf with respect to chloroplast ultrastructure, photosystem II (PSII) quantum yield, and phosphoenolpyruvate carboxylase (PEPCase; EC 4.1.1.31) activity. Transmission electron microscope observations showed well-developed chloroplasts with numerous granum stacks at grain-filling stages 1, 2 and 3 in both the flag leaf and the exposed peduncle. In the exposed peduncle, the membranes constituting the thylakoids were very distinct and plentiful, but in the flag leaf, there was a sharp breakdown at stage 4 and complete disintegration of the thylakoid membranes at stage 5. PSII quantum yield assays revealed that the photosynthetic efficiency remained constant at stages 1, 2 and 3 and then declined in both organs. However, the decline occurred more dramatically in the flag leaf than in the exposed peduncle. An enzyme assay showed that at stages 1 and 2 the PEPCase activity was lower in the exposed peduncle than in the flag leaf; but at stages 3, 4 and 5 the value was higher in the exposed peduncle, with a particularly significant difference observed at stage 5. Subjecting the exposed part of the peduncle to darkness following anthesis reduced the rate of grain growth. Our results suggest that the exposed peduncle is a photosynthetically active organ that produces photosynthates and thereby makes a crucial contribution to grain growth, particularly during the late stages of grain-filling.
Gurieva, Tanya; Bootsma, Martin C. J.; Bonten, Marc J. M.
2013-01-01
Nosocomial infection rates due to antibiotic-resistant bacteriae, e.g., methicillin-resistant Staphylococcus aureus (MRSA) remain high in most countries. Screening for MRSA carriage followed by barrier precautions for documented carriers (so-called screen and isolate (S&I)) has been successful in some, but not all settings. Moreover, different strategies have been proposed, but comparative studies determining their relative effects and costs are not available. We, therefore, used a mathematical model to evaluate the effect and costs of different S&I strategies and to identify the critical parameters for this outcome. The dynamic stochastic simulation model consists of 3 hospitals with general wards and intensive care units (ICUs) and incorporates readmission of carriers of MRSA. Patient flow between ICUs and wards was based on real observations. Baseline prevalence of MRSA was set at 20% in ICUs and hospital-wide at 5%; ranges of costs and infection rates were based on published data. Four S&I strategies were compared to a do-nothing scenario: S&I of previously documented carriers (“flagged” patients); S&I of flagged patients and ICU admissions; S&I of flagged and group of “frequent” patients; S&I of all hospital admissions (universal screening). Evaluated levels of efficacy of S&I were 10%, 25%, 50% and 100%. Our model predicts that S&I of flagged and S&I of flagged and ICU patients are the most cost-saving strategies with fastest return of investment. For low isolation efficacy universal screening and S&I of flagged and “frequent” patients may never become cost-saving. Universal screening is predicted to prevent hardly more infections than S&I of flagged and “frequent” patients, albeit at higher costs. Whether an intervention becomes cost-saving within 10 years critically depends on costs per infection in ICU, costs of screening and isolation efficacy. PMID:23436984
Youth Football Injuries: A Prospective Cohort
Peterson, Andrew R.; Kruse, Adam J.; Meester, Scott M.; Olson, Tyler S.; Riedle, Benjamin N.; Slayman, Tyler G.; Domeyer, Todd J.; Cavanaugh, Joseph E.; Smoot, M. Kyle
2017-01-01
Background: There are approximately 2.8 million youth football players between the ages of 7 and 14 years in the United States. Rates of injury in this population are poorly described. Recent studies have reported injury rates between 2.3% and 30.4% per season and between 8.5 and 43 per 1000 exposures. Hypothesis: Youth flag football has a lower injury rate than youth tackle football. The concussion rates in flag football are lower than in tackle football. Study Design: Cohort study; Level of evidence, 3. Methods: Three large youth (grades 2-7) football leagues with a total of 3794 players were enrolled. Research personnel partnered with the leagues to provide electronic attendance and injury reporting systems. Researchers had access to deidentified player data and injury information. Injury rates for both the tackle and flag leagues were calculated and compared using Poisson regression with a log link. The probability an injury was severe and an injury resulted in a concussion were modeled using logistic regression. For these 2 responses, best subset model selection was performed, and the model with the minimum Akaike information criterion value was chosen as best. Kaplan-Meier curves were examined to compare time loss due to injury for various subgroups of the population. Finally, time loss was modeled using Cox proportional hazards regression models. Results: A total of 46,416 exposures and 128 injuries were reported. The mean age at injury was 10.64 years. The hazard ratio for tackle football (compared with flag football) was 0.45 (95% CI, 0.25-0.80; P = .0065). The rate of severe injuries per exposure for tackle football was 1.1 (95% CI, 0.33-3.4; P = .93) times that of the flag league. The rate for concussions in tackle football per exposure was 0.51 (95% CI, 0.16-1.7; P = .27) times that of the flag league. Conclusion: Injury is more likely to occur in youth flag football than in youth tackle football. Severe injuries and concussions were not significantly different between leagues. Concussion was more likely to occur during games than during practice. Players in the sixth or seventh grade were more likely to suffer a concussion than were younger players. PMID:28255566
Sulfide geochronlogy along the Southwest Indian Ridge
NASA Astrophysics Data System (ADS)
Yang, W.; Tao, C.; Li, H.; Liang, J.; Liao, S.
2017-12-01
Dragon Flag and Duanqiao hydrothermal field is located between the Indomed and Gallieni fracture zones in the ultraslow-spreading Southwest Indian Ridge (SWIR). Ten subsamples from active and inactive vents of Dragon Flag hydrothermal field and twenty-eight subsamples from Duanqiao hydrothermal field were dated using the 230Th/238U method. Four main episodes of hydrothermal activity of Duanqiao were determined according to the restricted results: 68.9-84.3, 43.9-48.4, 25.3-34.8, and 0.7-17.3 kyrs. Hydrothermal activity of Duanqiao probably started about 84.3 (±0.5) kyrs ago and ceased about 0.737 (±0.023) kyrs ago. And sulfide samples from the nearby Dragon Flag filed at the same time and the results show that the ages of most sulfides from Dragon Flag field range from 1.496(±0.176) to 5.416 (±0.116) kyrs with the oldest age estimated at 15.997 (±0.155) kyrs Münch et al. (2001) reconstructed the evolution history of Mt. Jourdanne hydrothermal field. The age dating results indicate activity in two episodes, at 70-40 and 27-13 kyrs. The hydrothermal activity in Dragon Flag field is much more recent than that of Duanqiao or Mt. Jourdanne fields. The massive sulfides are younger than the sulfides from other hydrothermal fields such as Rainbow, Sonne and Ashadze-2. All these results suggest that hydrothermal activity of Dragon Flag field is much more recent than that of Duanqiao or Mt. Jourdanne fields. Mt. Jourdanne is situated on an axial volcanic ridge which has both volcanic and tectonic activity. This is necessary to develop the heat source and pathways for the fluid convection, which enables the hydrothermal circulation. Hydrothermal activity in Dragon Flag Field is located next to the detachment fault termination. The detachment fault system provides a pathway for hydrothermal convection. Such style of heat source can contribute to continuous hydrothermal activity for over 1000 years. Duanqiao field is located near the central volcano and there is a hot mantle and/or fertile melt beneath Duanqiao field. The crust thickness is 9.5 km, suggesting the existence of AMC (Axial Magma Chamber) which provides magma source to the field (Li et al. 2015; Mendel et al. 2003). The periodic hydrothermal activity at Duanqiao may be related to the heat source provided by the local interaction of magmatism and tectonism.
ERIC Educational Resources Information Center
Instructor, 1982
1982-01-01
Ten seasonal plays are presented: (1) September (nutrition); (2) October (Halloween); (3) November (Thanksgiving); (4 and 5) December (Hanukkah, Christmas); (6) January (Martin Luther King, Jr.); (7) February (friendship); (8) March (Saint Patrick's Day); (9) April (Easter); and (10) May/June (Memorial and Flag Days). (CJ)
High School and Beyond. 1980 Sophomore Cohort. First Follow-Up (1982). [machine-readable data file].
ERIC Educational Resources Information Center
National Center for Education Statistics (ED), Washington, DC.
The High School and Beyond 1980 Sophomore Cohort First Follow-Up (1982) data file is presented. The First Follow-Up Sophomore Cohort data tape consists of four related data files: (1) the student data file (including data availability flags, weights, questionnaire data, and composite variables); (2) Statistical Analysis System (SAS) control cards…
Examining the Seven-Flag "Chieu Hoi" Pass: A Primary Document from the American War in Viet Nam
ERIC Educational Resources Information Center
Engelmann, Ted
2006-01-01
During the Viet Nam war, U.S. military helicopters dropped "Chieu Hoi" (safe conduct) passes over suspected enemy locations to encourage enemy soldiers to surrender. This article presents a classroom activity that encourages students to examine a "Chieu Hoi" pass as a primary historical document, identify its various elements,…
41 CFR 301-10.131 - What does United States mean?
Code of Federal Regulations, 2013 CFR
2013-07-01
... 41 Public Contracts and Property Management 4 2013-07-01 2012-07-01 true What does United States... Carrier Transportation Use of United States Flag Air Carriers § 301-10.131 What does United States mean? For purposes of the use of United States flag air carriers, United States means the 50 states, the...
41 CFR 301-10.131 - What does United States mean?
Code of Federal Regulations, 2010 CFR
2010-07-01
... 41 Public Contracts and Property Management 4 2010-07-01 2010-07-01 false What does United States... Carrier Transportation Use of United States Flag Air Carriers § 301-10.131 What does United States mean? For purposes of the use of United States flag air carriers, United States means the 50 states, the...
41 CFR 301-10.131 - What does United States mean?
Code of Federal Regulations, 2011 CFR
2011-07-01
... 41 Public Contracts and Property Management 4 2011-07-01 2011-07-01 false What does United States... Carrier Transportation Use of United States Flag Air Carriers § 301-10.131 What does United States mean? For purposes of the use of United States flag air carriers, United States means the 50 states, the...
41 CFR 301-10.131 - What does United States mean?
Code of Federal Regulations, 2014 CFR
2014-07-01
... 41 Public Contracts and Property Management 4 2014-07-01 2014-07-01 false What does United States... Carrier Transportation Use of United States Flag Air Carriers § 301-10.131 What does United States mean? For purposes of the use of United States flag air carriers, United States means the 50 states, the...
Eight Stars of Gold--The Story of Alaska's Flag. Primary Grade Activities.
ERIC Educational Resources Information Center
Alaska State Museum, Juneau.
This activities booklet focuses on the story of Alaska's flag. The booklet is intended for teachers to use with primary-grade children. Each activity in the booklet contains background information, a summary and time estimate, Alaska state standards, a step-by-step technique for implementing the activity, assessment tips, materials and resource…
Cornish Tin Mining and Smelting
ERIC Educational Resources Information Center
Gardner, Rebecca
2010-01-01
In this article, the author describes how Cornwall was once the world's leading producer of tin. Cornwall's industrial past is now a World Heritage Site alongside the Grand Canyon or the Great Wall of China. A hint is in the Cornish flag, a simple white cross against a black background, also known as Saint Piran's flag. At Geevor Tin Mine, one of…
ERIC Educational Resources Information Center
San Mateo County Office of Education, Redwood City, CA. SMERC Information Center.
Materials and activities for teaching about patriotism, the American flag, and the Pledge of Allegiance are offered in this compilation of articles taken from issues of "Grade Teacher" (Feb. 1952, Jun. 1954, Feb. 1958, Jun. 1960, Jun. 1962, Sep. 1971), and "Instructor" (Jun. 1962, Feb. 1975, Feb. 1983), magazines. The…
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-22
... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD-2011-0163] Use of Foreign-Flag Anchor Handling Vessels in the Beaufort Sea or Chukchi Sea Adjacent to Alaska AGENCY... 9199622) would operate in the Beaufort Sea or Chukchi Sea adjacent to Alaska, under certain conditions...
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-22
... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket Number MARAD 2010-0031] Use of Foreign-Flag Anchor Handling Vessels in the Beaufort Sea or Chukchi Sea Adjacent to Alaska AGENCY... 9199622) would operate in the Beaufort Sea or Chukchi Sea adjacent to Alaska, under certain conditions...
46 CFR 67.171 - Deletion; requirement and procedure.
Code of Federal Regulations, 2013 CFR
2013-10-01
... when: (1) The vessel is placed under foreign flag; (2) The vessel is sold or transferred in whole or in... placed under foreign flag or has been sold or transferred in whole or in part to a non-citizen of the... section, and file: (1) Evidence of the sale or transfer, if any; and (2) Evidence that the Maritime...
USDA-ARS?s Scientific Manuscript database
Stagonospora nodorum blotch (SNB) is a serious disease of wheat worldwide, and it is prevalent on winter wheat in many eastern states. Management relies mainly on fungicide application after flag leaf emergence. The disease can occur prior to flag leaf emergence, however, the impact of the time of ...
Using International Law to Defuse Current Controversies in the South and East China Seas
2015-02-01
7 Mid-Ocean Territorial Contests ................................................................................. 10 The Laissez - Faire ...to make similar claims. The Laissez - Faire Approach to Flag State Enforcement: The Flag of Convenience Problem The LOS Convention also recognizes...played an important thought- leadership role in oceans policy formulation and has supplied jurists to ITLOS and other arbitral tribunals, and has
14 CFR § 1221.106 - Establishment of the NASA Flag.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Establishment of the NASA Flag. § 1221.106 Section § 1221.106 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA...
14 CFR § 1221.113 - Use of the NASA Flags.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Use of the NASA Flags. § 1221.113 Section § 1221.113 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION THE NASA SEAL AND OTHER DEVICES, AND THE CONGRESSIONAL SPACE MEDAL OF HONOR NASA Seal, NASA Insignia, NASA Logotype, NASA...
Aggressive Students and High School Dropout: An Event History Analysis
ERIC Educational Resources Information Center
Orozco, Steven R.
2016-01-01
Aggressive students often struggle in multiple domains of their school functioning and are at increased risk for high school dropout. Research has identified a variety of warning flags which are strong predictors of high school dropout. While it is known that aggressive students exhibit many of these warning flags, there is little research which…
Eight Stars of Gold--The Story of Alaska's Flag. Intermediate Activities (Grades 3-5).
ERIC Educational Resources Information Center
Alaska State Museum, Juneau.
This activities booklet focuses on the story of Alaska's flag. The booklet is intended for teachers to use with students in the intermediate grades. Each activity in the booklet contains: background information, a summary and time estimate, state standards, a step-by-step technique for implementation of the activity, assessment tips, materials and…
ERIC Educational Resources Information Center
Dow, Deanna; Guthrie, Whitney; Stronach, Sheri T.; Wetherby, Amy M.
2017-01-01
The purpose of this study was to examine the utility of the Systematic Observation of Red Flags as an observational level-two screening measure to detect risk for autism spectrum disorder in toddlers when used with a video-recorded administration of the Communication and Symbolic Behavior Scales. Psychometric properties of the Systematic…
75 FR 64162 - Determination of Attainment for PM10
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-19
... AQS as a special event due to a volcanic eruption. Under EPA's 1994 guidance,\\4\\ data may be excluded... 1992-1994 period (all in 1992), these values were flagged by ADEC as special events due to a volcanic eruption. EPA concurred on the flagged exceedances in a May 24, 1995, letter to ADEC and thus these values...
48 CFR 752.247-70 - Preference for privately owned U.S.-flag commercial vessels.
Code of Federal Regulations, 2011 CFR
2011-10-01
..., depending on current compliance with Cargo Preference requirements. If freight under the contract is fixed... commodity. (viii) Gross weight in pounds and cubic feet if available. (ix) Total ocean freight revenue in U.S. dollars. Alternate I (d) If freight is fixed on a U.S. flag vessel, except as provided in...
48 CFR 752.247-70 - Preference for privately owned U.S.-flag commercial vessels.
Code of Federal Regulations, 2014 CFR
2014-10-01
..., depending on current compliance with Cargo Preference requirements. If freight under the contract is fixed... commodity. (viii) Gross weight in pounds and cubic feet if available. (ix) Total ocean freight revenue in U.S. dollars. Alternate I (d) If freight is fixed on a U.S. flag vessel, except as provided in...
48 CFR 752.247-70 - Preference for privately owned U.S.-flag commercial vessels.
Code of Federal Regulations, 2013 CFR
2013-10-01
..., depending on current compliance with Cargo Preference requirements. If freight under the contract is fixed... commodity. (viii) Gross weight in pounds and cubic feet if available. (ix) Total ocean freight revenue in U.S. dollars. Alternate I (d) If freight is fixed on a U.S. flag vessel, except as provided in...
48 CFR 752.247-70 - Preference for privately owned U.S.-flag commercial vessels.
Code of Federal Regulations, 2012 CFR
2012-10-01
..., depending on current compliance with Cargo Preference requirements. If freight under the contract is fixed... commodity. (viii) Gross weight in pounds and cubic feet if available. (ix) Total ocean freight revenue in U.S. dollars. Alternate I (d) If freight is fixed on a U.S. flag vessel, except as provided in...
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Fuel supply: Turbine-engine powered airplanes, other than turbo propeller: Flag and supplemental operations. 121.645 Section 121.645 Aeronautics... SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.645 Fuel supply: Turbine-engine powered...
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Fuel supply: Turbine-engine powered airplanes, other than turbo propeller: Flag and supplemental operations. 121.645 Section 121.645 Aeronautics... SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.645 Fuel supply: Turbine-engine powered...
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Fuel supply: Turbine-engine powered airplanes, other than turbo propeller: Flag and supplemental operations. 121.645 Section 121.645 Aeronautics... SUPPLEMENTAL OPERATIONS Dispatching and Flight Release Rules § 121.645 Fuel supply: Turbine-engine powered...
Code of Federal Regulations, 2014 CFR
2014-10-01
... vapor control system designs-TB/ALL. 39.1013 Section 39.1013 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS VAPOR CONTROL SYSTEMS General § 39.1013 U.S.-flagged tank vessel certification procedures for vapor control system designs—TB/ALL. (a) For an existing Coast Guard-approved vapor...
Code of Federal Regulations, 2014 CFR
2014-10-01
... vapor control system designs-TB/ALL. 39.1015 Section 39.1015 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS VAPOR CONTROL SYSTEMS General § 39.1015 Foreign-flagged tank vessel certification procedures for vapor control system designs—TB/ALL. As an alternative to meeting the requirements...
Code of Federal Regulations, 2013 CFR
2013-10-01
... vapor control system designs-TB/ALL. 39.1015 Section 39.1015 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS VAPOR CONTROL SYSTEMS General § 39.1015 Foreign-flagged tank vessel certification procedures for vapor control system designs—TB/ALL. As an alternative to meeting the requirements...
Code of Federal Regulations, 2013 CFR
2013-10-01
... vapor control system designs-TB/ALL. 39.1013 Section 39.1013 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS VAPOR CONTROL SYSTEMS General § 39.1013 U.S.-flagged tank vessel certification procedures for vapor control system designs—TB/ALL. (a) For an existing Coast Guard-approved vapor...
Eight Stars of Gold--The Story of Alaska's Flag. Middle School Activities (Grades 6-8).
ERIC Educational Resources Information Center
Alaska State Museum, Juneau.
This activities booklet focuses on the story of Alaska's state flag. The booklet is for use in teaching middle school students. Each activity contains: background information, a summary and time estimate, Alaska state standards, a step-by-step technique for classroom implementation of the activity, assessment tips, materials and resources needed,…
Eight Stars of Gold--The Story of Alaska's Flag. High School Activities (Grades 9-12).
ERIC Educational Resources Information Center
Alaska State Museum, Juneau.
This activities booklet focuses on the story of Alaska's flag. The booklet is intended for use in teaching high school students. Each activity contains: background information; a summary and time estimate, Alaska state standards, a step-by-step technique for classroom implementation of the activity, assessment tips, materials and resources needed,…
Environmental Assessment for the Joint Red Flag ADA Activities Nellis Air Force Base
2005-03-01
range ratany (Krameria erecta), cheesebush (Hymenoclea salsola), Mormon tea ( Ephedra spp.), and spiny menodora (Menodora spinescens). Four- wing...rattlesnake (Crotalus viridis lutosus), gopher snake (Pituophis melanoleucus), side-blotched lizards (Uta stansburiana) and western whiptails...viscidiflorus Sticky rabbitbrush Chrysothamnus nauseosus Rubber rabbitbrush Coleogyne ramosissima Blackbrush Ephedra sp. Mormon tea JOINT RED FLAG
Telling a Red Flag from the Real Threat with Students of Today
ERIC Educational Resources Information Center
Brunner, Judy; Lewis, Dennis
2006-01-01
With what seems like increasing frequency, secondary school administrators are being confronted with students' threats of violence. Unfortunately, some of the words that raise a red flag have now become part of the everyday language of many students, making it difficult to discern between the benign and the dangerous. Although all threats require…
Code of Federal Regulations, 2013 CFR
2013-01-01
.... Detecting Red Flags The Program's policies and procedures should address the detection of Red Flags in... Detection, Prevention, and Mitigation J Appendix J to Part 717 Banks and Banking NATIONAL CREDIT UNION...—Interagency Guidelines on Identity Theft Detection, Prevention, and Mitigation Section 717.90 of this part...
Code of Federal Regulations, 2012 CFR
2012-01-01
.... Detecting Red Flags The Program's policies and procedures should address the detection of Red Flags in... Detection, Prevention, and Mitigation J Appendix J to Part 717 Banks and Banking NATIONAL CREDIT UNION...—Interagency Guidelines on Identity Theft Detection, Prevention, and Mitigation Section 717.90 of this part...
Code of Federal Regulations, 2014 CFR
2014-01-01
.... Detecting Red Flags The Program's policies and procedures should address the detection of Red Flags in... Detection, Prevention, and Mitigation J Appendix J to Part 717 Banks and Banking NATIONAL CREDIT UNION...—Interagency Guidelines on Identity Theft Detection, Prevention, and Mitigation Section 717.90 of this part...
Code of Federal Regulations, 2011 CFR
2011-01-01
.... Detecting Red Flags The Program's policies and procedures should address the detection of Red Flags in... Detection, Prevention, and Mitigation J Appendix J to Part 717 Banks and Banking NATIONAL CREDIT UNION...—Interagency Guidelines on Identity Theft Detection, Prevention, and Mitigation Section 717.90 of this part...
14 CFR 121.637 - Takeoffs from unlisted and alternate airports: Domestic and flag operations.
Code of Federal Regulations, 2012 CFR
2012-01-01
... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Takeoffs from unlisted and alternate airports: Domestic and flag operations. 121.637 Section 121.637 Aeronautics and Space FEDERAL AVIATION... weather conditions at that airport are equal to or better than the following: (i) Airports in the United...
14 CFR 121.637 - Takeoffs from unlisted and alternate airports: Domestic and flag operations.
Code of Federal Regulations, 2011 CFR
2011-01-01
... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Takeoffs from unlisted and alternate airports: Domestic and flag operations. 121.637 Section 121.637 Aeronautics and Space FEDERAL AVIATION... weather conditions at that airport are equal to or better than the following: (i) Airports in the United...
14 CFR 121.637 - Takeoffs from unlisted and alternate airports: Domestic and flag operations.
Code of Federal Regulations, 2013 CFR
2013-01-01
... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Takeoffs from unlisted and alternate airports: Domestic and flag operations. 121.637 Section 121.637 Aeronautics and Space FEDERAL AVIATION... weather conditions at that airport are equal to or better than the following: (i) Airports in the United...
14 CFR 121.637 - Takeoffs from unlisted and alternate airports: Domestic and flag operations.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Takeoffs from unlisted and alternate airports: Domestic and flag operations. 121.637 Section 121.637 Aeronautics and Space FEDERAL AVIATION... weather conditions at that airport are equal to or better than the following: (i) Airports in the United...
14 CFR 121.637 - Takeoffs from unlisted and alternate airports: Domestic and flag operations.
Code of Federal Regulations, 2014 CFR
2014-01-01
... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Takeoffs from unlisted and alternate airports: Domestic and flag operations. 121.637 Section 121.637 Aeronautics and Space FEDERAL AVIATION... weather conditions at that airport are equal to or better than the following: (i) Airports in the United...
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2013-01-14
... Bridge Navigational Watch Alarm Systems (BNWAS) Aboard U.S. Flagged Vessels AGENCY: Coast Guard, DHS... carriage standards for Bridge Navigational Watch Alarm Systems (BNWAS), in accordance with the Articles of... carriage of a BNWAS should not lead to a reduction in manning levels on the bridge. Consistent with the...
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2013-10-22
...'') to add orders yielding Flag AA to the calculation of the average daily trading (``ADV'') threshold... AA to the calculation of the ADV threshold required to meet the MidPoint Match Volume Tier. Footnote... Match using MidPoint Match order type). The Exchange proposes to add orders yielding Flag AA (MidPoint...
Raising FLAGS: Renewing Core French at the Pre-Service Teacher Level
ERIC Educational Resources Information Center
Carr, Wendy
2010-01-01
A new program for core French teacher candidates called FLAGS (French Language and Global Studies) was established at the University of British Columbia (UBC) in 2007. The program is intended for those who are keen to teach core French and possess rudimentary proficiency in the language but may not necessarily have the same proficiency or prior…
Power enhancement via multivariate outlier testing with gene expression arrays.
Asare, Adam L; Gao, Zhong; Carey, Vincent J; Wang, Richard; Seyfert-Margolis, Vicki
2009-01-01
As the use of microarrays in human studies continues to increase, stringent quality assurance is necessary to ensure accurate experimental interpretation. We present a formal approach for microarray quality assessment that is based on dimension reduction of established measures of signal and noise components of expression followed by parametric multivariate outlier testing. We applied our approach to several data resources. First, as a negative control, we found that the Affymetrix and Illumina contributions to MAQC data were free from outliers at a nominal outlier flagging rate of alpha=0.01. Second, we created a tunable framework for artificially corrupting intensity data from the Affymetrix Latin Square spike-in experiment to allow investigation of sensitivity and specificity of quality assurance (QA) criteria. Third, we applied the procedure to 507 Affymetrix microarray GeneChips processed with RNA from human peripheral blood samples. We show that exclusion of arrays by this approach substantially increases inferential power, or the ability to detect differential expression, in large clinical studies. http://bioconductor.org/packages/2.3/bioc/html/arrayMvout.html and http://bioconductor.org/packages/2.3/bioc/html/affyContam.html affyContam (credentials: readonly/readonly)
Workers painting the Flag and Meatball on the VAB
2007-01-03
Elevated platforms are seen hanging in front of the NASA Logo on the side of Kennedy Space Center's Vehicle Assembly Building. Also in view on the east side of the building are platforms on the facility's large vertical doors. Workers, suspended on the platforms from the top of the 525-foot-high VAB, use rollers and brushes to do the painting. The flag and logo were last painted in 1998, honoring NASA's 40th anniversary. The flag spans an area 209 feet by 110 feet, or about 23, 437 square feet. Each stripe is 9 feet wide and each star is 6 feet in diameter. The logo, also known as the "meatball," measures 110 feet by 132 feet, or about 12,300 square feet.
Anomalous Hydrodynamic Drafting of Interacting Flapping Flags
NASA Astrophysics Data System (ADS)
Ristroph, Leif; Zhang, Jun
2008-11-01
In aggregates of objects moving through a fluid, bodies downstream of a leader generally experience reduced drag force. This conventional drafting holds for objects of fixed shape, but interactions of deformable bodies in a flow are poorly understood, as in schools of fish. In our experiments on “schooling” flapping flags, we find that it is the leader of a group who enjoys a significant drag reduction (of up to 50%), while the downstream flag suffers a drag increase. This counterintuitive inverted drag relationship is rationalized by dissecting the mutual influence of shape and flow in determining drag. Inverted drafting has never been observed with rigid bodies, apparently due to the inability to deform in response to the altered flow field of neighbors.
Development of the Solar System Concept Inventory
NASA Astrophysics Data System (ADS)
Hornstein, S.; Prather, E.
2009-12-01
Concept inventories can provide useful insight into students’ understanding of key physical concepts. Knowing what your students have learned during a course is a valuable tool for improving your own teaching. Unfortunately, current astronomy concept inventories are not suitable for an introductory solar system course because they either cover too broad of a range of topics (e.g. Astronomy Diagnostic Test) or are too narrowly focused (e.g. Greenhouse Effect Concept Inventory, Lunar Phase Concept Inventory). We have developed the Solar System Concept Inventory (SSCI) to cover those topics commonly taught in an introductory solar system course. The topics included on the SSCI were selected by having faculty identify the key concepts they address when teaching about the solar system. SSCI topics include formation mechanisms, planetary interiors, atmospheric effects, and small solar system bodies. Student interviews were conducted to identify common naive ideas and reasoning difficulties relating to these key topics. The SSCI has been through two semesters of national, multi-institutional field-testing, involving over 1500 students. After the first semester of testing, question statistics were used to flag ineffective questions and flagged questions were revised or eliminated. We will present an overall outline of the SSCI development as well as our question-flagging criteria and question analyses from the latest round of field-testing. We would like to thank the NSF for funding under Grant No. 0715517, a CCLI Phase III Grant for the Collaboration of Astronomy Teaching Scholars (CATS) Program.