Global supply and demand of metals in the future.

PubMed

Backman, Carl-Magnus

2008-01-01

This article is a short review on the subject of diminishing mineral resources in a world with increasing population. The concepts of reserves, resources, and life index are described. A forecast is made on the global consumption in the year 2050 of the metals iron (Fe), aluminum (Al), copper (Cu), zinc (Zn), nickel (Ni), and lead (Pb). Evidence indicates that a physical depletion of metals does not occur (fixed stock paradigm) but certain metals will become too expensive to extract (opportunity cost paradigm). The future demand for cadmium (Cd), mercury (Hg), arsenic (As), and selenium (Se) is presented. Finally, some metals presently of great interest for mineral prospectors that may have an important role in the future society are presented.

Comprehensive Environmental Assessment Applied to ...

EPA Pesticide Factsheets

In September 2013, EPA announced the availability of the final report, Comprehensive Environmental Assessment Applied to Multiwalled Carbon Nanotube Flame-Retardant Coatings in Upholstery Textiles: A Case Study Presenting Priority Research Gaps for Future Risk Assessments. This final report presents a case study of multiwalled carbon nanotubes (MWCNTs); it focuses on the specific example of MWCNTs as used in flame-retardant coatings applied to upholstery textiles. This case study is organized around the comprehensive environmental assessment (CEA) framework, which structures available information pertaining to the product life cycle, environmental transport and fate, exposure-dose in receptors (i.e., humans, ecological populations, and the environment), and potential impacts in these receptors. A group of experts representing multiple disciplines and multiple sector perspectives used an earlier draft of the case study in conjunction with a structured workshop process to identify and prioritize research gaps that, if pursued, could inform future MWCNT assessment efforts. The final report is not a health, risk, or exposure assessment and as such does not draw conclusions about potential risks, or present an exhaustive review of the literature. Rather, it presents the MWCNT research priorities that experts identified in this application of CEA in order to aid research planning throughout the scientific community. The outcomes of these research efforts may subsequ

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lei, Hongzhuan; Lu, Zhiming; Vesselinov, Velimir Valentinov

These are slides from a presentation on identifying heterogeneities in subsurface environment using the level set method. The slides start with the motivation, then explain Level Set Method (LSM), the algorithms, some examples are given, and finally future work is explained.

Future NASA Power Technologies for Space and Aero Propulsion Applications

NASA Technical Reports Server (NTRS)

Soeder, James F.

2015-01-01

To achieve the ambitious goals that NASA has outlined for the next decades considerable development of power technology will be necessary. This presentation outlines the development objectives for both space and aero applications. It further looks at the various power technologies that support these objectives and examines drivers that will be a driving force for future development. Finally, the presentation examines what type of non-traditional learning areas should be emphasized in student curriculum so that the engineering needs of the third decade of the 21st Century are met.

Comparative Cognition: Past, Present, and Future

PubMed Central

Beran, Michael J.; Parrish, Audrey E.; Perdue, Bonnie M.; Washburn, David A.

2014-01-01

Comparative cognition is the field of inquiry concerned with understanding the cognitive abilities and mechanisms that are evident in nonhuman species. Assessments of animal cognition have a long history, but in recent years there has been an explosion of new research topics, and a general broadening of the phylogenetic map of animal cognition. To review the past of comparative cognition, we describe the historical trends. In regards to the present state, we examine current “hot topics” in comparative cognition. Finally, we offer our unique and combined thoughts on the future of the field. PMID:25419047

The potential impact of MMICs on future satellite communications

NASA Technical Reports Server (NTRS)

Dunn, Vernon E.

1988-01-01

This is the Final Report representing the results of a 17-month study on the future trends and requirements of Monolithic Microwave Integrated Circuits (MMIC) for space communication applications. Specifically this report identifies potential space communication applications of MMICs, assesses the impact of MMIC on the classes of systems that were identified, determines the present status and probable 10-year growth in capability of required MMIC and competing technologies, identifies the applications most likely to benefit from further MMIC development and presents recommendations for NASA development activities to address the needs of these applications.

A "present" for the future: the unexpected value of rediscovery.

PubMed

Zhang, Ting; Kim, Tami; Brooks, Alison Wood; Gino, Francesca; Norton, Michael I

2014-10-01

Although documenting everyday activities may seem trivial, four studies reveal that creating records of the present generates unexpected benefits by allowing future rediscoveries. In Study 1, we used a time-capsule paradigm to show that individuals underestimate the extent to which rediscovering experiences from the past will be curiosity provoking and interesting in the future. In Studies 2 and 3, we found that people are particularly likely to underestimate the pleasure of rediscovering ordinary, mundane experiences, as opposed to extraordinary experiences. Finally, Study 4 demonstrates that underestimating the pleasure of rediscovery leads to time-inconsistent choices: Individuals forgo opportunities to document the present but then prefer rediscovering those moments in the future to engaging in an alternative fun activity. Underestimating the value of rediscovery is linked to people's erroneous faith in their memory of everyday events. By documenting the present, people provide themselves with the opportunity to rediscover mundane moments that may otherwise have been forgotten. © The Author(s) 2014.

Studies in Family Planning, Volume 3, Number 5.

ERIC Educational Resources Information Center

Population Council, New York, NY.

The Commission on Population Growth and the American Future was established by Congress in March, 1970, to examine the impact of population change in the United States to the year 2000. Excerpts from their final report, submitted in March, 1972, are presented in this pamphlet. The first eight chapters focus on the present and prospective…

Development of a high resolution stepper motor prototype. Volume 2. Detailed results. Volume 3. Development rapport final relatif a un prototype de moteur pas a pas a grande resolution. Volume 2. Resultats detailles. Volume 3. Developpement. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1975-12-01

This motor could be used to drive large solar panels of future satellites. Results of investigations concerning a breadboard model without a relaxation torque and a prototype with a relaxation torque are presented. For volume 1; see ESR-97066. (GRA)

[Research in space environmental medicine: review and future].

PubMed

Yu, Xue-jun; Qi, Zhang-nian; Chang, Shao-yong; Liang, Hong; Liu, Hong-tao

2003-01-01

The investigation progress of space environmental medicine in China is summarized. Then, the application of space environmental medicine to formulating medical requirements for the crew module design, and performing medical evaluation for Shenzhou spaceship are addressed. Additionally, the medical and engineering means for the protection from harmful agents during spaceflight is illustrated. Finally, the objective and challenge of space environment medicine faced in the future research in China are presented.

Investigation of hot mix asphalt mixtures at Mn/ROAD : final report

DOT National Transportation Integrated Search

1997-02-01

This report presents the material characterization for the Minnesota Road Research Project (Mn/ROAD) bituminous materials. This effort will provide the historical base line information on properties needed for the validation of future pavement evalua...

General aviation components. [performance and capabilities of general aviation aircraft

NASA Technical Reports Server (NTRS)

1975-01-01

An overview is presented of selected aviation vehicles. The capabilities and performance of these vehicles are first presented, followed by a discussion of the aerodynamics, structures and materials, propulsion systems, noise, and configurations of fixed-wing aircraft. Finally the discussion focuses on the history, status, and future of attempts to provide vehicles capable of short-field operations.

Automated Cooperative Trajectories

NASA Technical Reports Server (NTRS)

Hanson, Curt; Pahle, Joseph; Brown, Nelson

2015-01-01

This presentation is an overview of the Automated Cooperative Trajectories project. An introduction to the phenomena of wake vortices is given, along with a summary of past research into the possibility of extracting energy from the wake by flying close parallel trajectories. Challenges and barriers to adoption of civilian automatic wake surfing technology are identified. A hardware-in-the-loop simulation is described that will support future research. Finally, a roadmap for future research and technology transition is proposed.

High-Reflection Coatings for Gravitational-Wave Detectors: State of The Art and Future Developments

NASA Astrophysics Data System (ADS)

Amato, Alex; Cagnoli, Gianpietro; Canepa, Maurizio; Coillet, Elodie; Degallaix, Jerome; Dolique, Vincent; Forest, Daniele; Granata, Massimo; Martinez, Valérie; Michel, Christophe; Pinard, Laurent; Sassolas, Benoit; Teillon, Julien

2018-02-01

We report on the optical, mechanical and structural characterization of the sputtered coating materials of Advanced LIGO, Advanced Virgo and KAGRA gravitational- waves detectors. We present the latest results of our research program aiming at decreasing coating thermal noise through doping, optimization of deposition parameters and post- deposition annealing. Finally, we propose sputtered Si3N4 as a candidate material for the mirrors of future detectors.

Navier-Stokes computations useful in aircraft design

NASA Technical Reports Server (NTRS)

Holst, Terry L.

1990-01-01

Large scale Navier-Stokes computations about aircraft components as well as reasonably complete aircraft configurations are presented and discussed. Speed and memory requirements are described for various general problem classes, which in some cases are already being used in the industrial design environment. Recent computed results, with experimental comparisons when available, are included to highlight the presentation. Finally, prospects for the future are described and recommendations for areas of concentrated research are indicated. The future of Navier-Stokes computations is seen to be rapidly expanding across a broad front of applications, which includes the entire subsonic-to-hypersonic speed regime.

DNA origami nanopores: developments, challenges and perspectives

NASA Astrophysics Data System (ADS)

Hernández-Ainsa, Silvia; Keyser, Ulrich F.

2014-11-01

DNA nanotechnology has enabled the construction of DNA origami nanopores; synthetic nanopores that present improved capabilities for the area of single molecule detection. Their extraordinary versatility makes them a new and powerful tool in nanobiotechnology for a wide range of important applications beyond molecular sensing. In this review, we briefly present the recent developments in this emerging field of research. We discuss the current challenges and possible solutions that would enhance the sensing capabilities of DNA origami nanopores. Finally, we anticipate novel avenues for future research and highlight a range of exciting ideas and applications that could be explored in the near future.

Superfund record of decision (EPA Region 5): Skinner Landfill, West Chester, OH, June 1993

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-06-04

The decision document presents the selected final remedial action for the Skinner Landfill site in West Chester, Ohio. The remedy is the second and final of two operable units for this site. The first operable unit addressed immediate site concerns, through the construction of a fence around the contaminated area, and by offering an alternate supply of drinking water to the potentially affected users of groundwater. This final operable unit addresses potential future migration of site contaminants into the groundwater and will limit the potential for direct exposure of site contaminants to humans through source control measures.

Vinculacion Entre La Educacion Y El Mundo Del Trabajo: Informe Final. (Coloquio Regional Caracas, Venezuela, Septiembre 2-6, 1985) = The Linkage Between Education and Employment: Final Report of the Regional Colloquium (Caracas, Venezuela, September 2-6, 1985).

ERIC Educational Resources Information Center

United Nations Educational, Scientific, and Cultural Organization, Santiago (Chile). Regional Office for Education in Latin America and the Caribbean.

At this regional colloquium 13 papers were presented concerning the relationship between education and employment. Themes addressed were: (1) the transformation of the workplace by technology and science; (2) the future of the disadvantaged population as a consequence of the technological revolution; and (3) the resulting changes in the education…

17 CFR 171.42 - Notice of a final decision of the National Futures Association in a member responsibility action.

Code of Federal Regulations, 2014 CFR

2014-04-01

... RESPONSIBILITY ACTIONS Commission Review of Decisions by the National Futures Association In Member Responsibility Actions § 171.42 Notice of a final decision of the National Futures Association in a member... well as the Proceeding Clerk and Secretary of the Commission, with a written notice of any final...

Photovoltaics: The endless spring

NASA Technical Reports Server (NTRS)

Brandhorst, H. W., Jr.

1984-01-01

An overview of the developments in the photovoltaic field over the past decade or two is presented. Accomplishments in the terrestrial field are reviewed along with projections and challenges toward meeting cost goals. The contrasts and commonality of space and terrestrial photovoltaics are presented. Finally, a strategic philosophy of photovoltaics research highlighting critical factors, appropriate directions, emerging opportunities, and challenges of the future is given.

US Navy SHF SATCOM: Past, present and future

NASA Astrophysics Data System (ADS)

Bushnell, Christopher J.

1994-06-01

This thesis discusses the Navy's Super High Frequency Satellite Communications (SHF SATCOM) capabilities prior to Desert Shield/Desert Storm, and the requirements for future systems that were generated due to Navy SATCOM shortcomings during the Gulf War. The four-phased evolutionary approach the Navy has designed (based on post-war requirements) to provide itself with a medium for SHF SATCOM into the 21st Century, as well as the Defense Satellite Communications Systems (DSCS), are examined in detail. Decreasing defense budgets have begun to have a significant impact on future military satellite communication (MILSATCOM) systems. A cost comparison between utilization of DSCS III satellites and the INMARSAT commercial SATCOM system is presented. Recommended improvements to current MILSATCOM procedures and training practices are proposed that could improve operational C4I capabilities. Finally, this study determines that future SATCOM architectures should include a mixture of commercial systems and MILSATCOM systems to provide both cost savings and command and control protection.

Demonstration of TRAF-NETSIM for traffic operations management : final report.

DOT National Transportation Integrated Search

1991-08-01

The utility of the simulation package TRAF-NETSIM to the traffic engineer is assessed and demonstrated by means of a case study. The methodology employed in performing the analysis is presented in a way that will aid future users of TRAF-NETSIM. The ...

Counseling and Mental Health Care in Palestine

ERIC Educational Resources Information Center

Shawahin, Lamise; Ciftci, Ayse

2012-01-01

The authors provide a brief overview of counseling and mental health care in Palestine, including their history and a summary of their current status. Finally, a discussion is presented of future trends in the development of the profession with regard to recent changes in the region.

17 CFR 171.42 - Notice of a final decision of the National Futures Association in a member responsibility action.

Code of Federal Regulations, 2012 CFR

2012-04-01

... ACTIONS Commission Review of Decisions by the National Futures Association In Member Responsibility Actions § 171.42 Notice of a final decision of the National Futures Association in a member responsibility... the Proceeding Clerk and Secretary of the Commission, with a written notice of any final decision in a...

17 CFR 171.42 - Notice of a final decision of the National Futures Association in a member responsibility action.

Code of Federal Regulations, 2013 CFR

2013-04-01

... ACTIONS Commission Review of Decisions by the National Futures Association In Member Responsibility Actions § 171.42 Notice of a final decision of the National Futures Association in a member responsibility... the Proceeding Clerk and Secretary of the Commission, with a written notice of any final decision in a...

17 CFR 171.42 - Notice of a final decision of the National Futures Association in a member responsibility action.

Code of Federal Regulations, 2010 CFR

2010-04-01

... ACTIONS Commission Review of Decisions by the National Futures Association In Member Responsibility Actions § 171.42 Notice of a final decision of the National Futures Association in a member responsibility... the Proceeding Clerk and Secretary of the Commission, with a written notice of any final decision in a...

17 CFR 171.42 - Notice of a final decision of the National Futures Association in a member responsibility action.

Code of Federal Regulations, 2011 CFR

2011-04-01

... ACTIONS Commission Review of Decisions by the National Futures Association In Member Responsibility Actions § 171.42 Notice of a final decision of the National Futures Association in a member responsibility... the Proceeding Clerk and Secretary of the Commission, with a written notice of any final decision in a...

Analysis and application of intelligence network based on FTTH

NASA Astrophysics Data System (ADS)

Feng, Xiancheng; Yun, Xiang

2008-12-01

With the continued rapid growth of Internet, new network service emerges in endless stream, especially the increase of network game, meeting TV, video on demand, etc. The bandwidth requirement increase continuously. Network technique, optical device technical development is swift and violent. FTTH supports all present and future service with enormous bandwidth, including traditional telecommunication service, traditional data service and traditional TV service, and the future digital TV and VOD. With huge bandwidth of FTTH, it wins the final solution of broadband network, becomes the final goal of development of optical access network. Firstly, it introduces the main service which FTTH supports, main analysis key technology such as FTTH system composition way, topological structure, multiplexing, optical cable and device. It focus two kinds of realization methods - PON, P2P technology. Then it proposed that the solution of FTTH can support comprehensive access (service such as broadband data, voice, video and narrowband private line). Finally, it shows the engineering application for FTTH in the district and building. It brings enormous economic benefits and social benefit.

Weak lensing in the Dark Energy Survey

NASA Astrophysics Data System (ADS)

Troxel, Michael

2016-03-01

I will present the current status of weak lensing results from the Dark Energy Survey (DES). DES will survey 5000 square degrees in five photometric bands (grizY), and has already provided a competitive weak lensing catalog from Science Verification data covering just 3% of the final survey footprint. I will summarize the status of shear catalog production using observations from the first year of the survey and discuss recent weak lensing science results from DES. Finally, I will report on the outlook for future cosmological analyses in DES including the two-point cosmic shear correlation function and discuss challenges that DES and future surveys will face in achieving a control of systematics that allows us to take full advantage of the available statistical power of our shear catalogs.

The past, present and future of renin–angiotensin aldosterone system inhibition☆

PubMed Central

Mentz, Robert J.; Bakris, George L.; Waeber, Bernard; McMurray, John J.V.; Gheorghiade, Mihai; Ruilope, Luis M.; Maggioni, Aldo P.; Swedberg, Karl; Piña, Ileana L.; Fiuzat, Mona; O’Connor, Christopher M.; Zannad, Faiez; Pitt, Bertram

2014-01-01

The renin–angiotensin aldosterone system (RAAS) is central to the pathogenesis of cardiovascular disease. RAAS inhibition can reduce blood pressure, prevent target organ damage in hypertension and diabetes, and improve outcomes in patients with heart failure and/or myocardial infarction. This review presents the history of RAAS inhibition including a summary of key heart failure, myocardial infarction, hypertension and atrial fibrillation trials. Recent developments in RAAS inhibition are discussed including implementation and optimization of current drug therapies. Finally, ongoing clinical trials, opportunities for future trials and issues related to the barriers and approvability of novel RAAS inhibitors are highlighted. PMID:23121914

Cargo Logistics Airlift Systems Study (CLASS). Volume 1: Analysis of current air cargo system

NASA Technical Reports Server (NTRS)

Burby, R. J.; Kuhlman, W. H.

1978-01-01

The material presented in this volume is classified into the following sections; (1) analysis of current routes; (2) air eligibility criteria; (3) current direct support infrastructure; (4) comparative mode analysis; (5) political and economic factors; and (6) future potential market areas. An effort was made to keep the observations and findings relating to the current systems as objective as possible in order not to bias the analysis of future air cargo operations reported in Volume 3 of the CLASS final report.

Telerehabilitation robotics: bright lights, big future?

PubMed

Carignan, Craig R; Krebs, Hermano I

2006-01-01

The potential for remote diagnosis and treatment over the Internet using robotics is now a reality. The state of the art is exemplified by several Internet applications, and we explore the current trends in developing new systems. We review the technical challenges that lie ahead, along with some potential solutions. Some promising results for a new bilateral system involving two InMotion2 robots are presented. Finally, we discuss the future direction and commercial outlook for rehabilitation robots over the next 15 years.

Impact of reconstructive transplantation on the future of plastic and reconstructive surgery.

PubMed

Siemionow, Maria

2012-10-01

This article summarizes the current knowledge on the new developing field of reconstructive transplantation. A brief outline of vascularized composite allografts (VCA) such as human hand, face, larynx, and abdominal wall transplants is provided. The clinical applications and indications for these new reconstructive transplantation procedures are outlined. The advantages, disadvantages, and complications and concerns surrounding clinical VCA are discussed. Finally, the impact of reconstructive transplantation on the future of plastic and reconstructive surgery is presented. Copyright © 2012 Elsevier Inc. All rights reserved.

UTEX: integrated ultraviolet and x-ray astronomy facility on spacelab, phase a study. Volume 2: facility definition. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1976-07-01

The definition and feasibility study of an integrated ultraviolet and astronomy facility onboard Spacelab are presented. This is based on the scientific aims of different European countries. The accommodation of such a facility in the first and second Spacelab flights was also studied, taking into account external constraints of both flights and the possibility of future missions. Well identified possible work packages are outlined in view of future international cooperation.

Profile of software engineering within the National Aeronautics and Space Administration (NASA)

NASA Technical Reports Server (NTRS)

Sinclair, Craig C.; Jeletic, Kellyann F.

1994-01-01

This paper presents findings of baselining activities being performed to characterize software practices within the National Aeronautics and Space Administration. It describes how such baseline findings might be used to focus software process improvement activities. Finally, based on the findings to date, it presents specific recommendations in focusing future NASA software process improvement efforts. The findings presented in this paper are based on data gathered and analyzed to date. As such, the quantitative data presented in this paper are preliminary in nature.

The first GCC Marine Biotechnology Symposium: Emerging Opportunities and Future Perspectives.

PubMed

Goddard, Stephen; Delghandi, Madjid; Dobretsov, Sergey; Al-Oufi, Hamed; Al-Habsi, Saoud; Burgess, J Grant

2015-06-01

With its diverse, living marine resources and rapidly growing educational and research infrastructure, the Sultanate of Oman is well-positioned to take advantage of the commercial opportunities presented by marine biotechnology. In recognition of potential development, an international symposium, Marine Biotechnology-Emerging Opportunities and Future Perspectives, was held in Muscat, November 12-13, 2013. Three keynote addresses were given, 23 oral presentations made, and a poster exhibition held. The final session reviewed national and regional issues, and the delegates agreed informally on a number of future actions. The potential for future development of marine biotechnology was recognized by all delegates, and following the symposium, they were surveyed for their views on how best to sustain and develop new activities. One hundred percent of respondents found the meeting useful and would support future symposia in the region. Fifty-one percent of Omani respondents recognized major organizational challenges and obstacles to the development of marine biotechnology compared with 23 % of overseas respondents. The need for greater collaboration between research institutions within the GCC region was recognized by 98 % of all respondents. The presentations and survey outcomes are reviewed in this paper.

Determining Adult Agribusiness Training Needs. Final Report.

ERIC Educational Resources Information Center

Ahrens, Donald L.; And Others

The prupose of the study was to: (1) identify the agribusiness firms within Wisconsin's Vocational-Technical and Adult Education (VTAE) District One, (2) identify the occupations of those employed in the industry, (3) identify present and future employment need for identified skills along with training needs for those currently employed in…

Impact of Future Cable Television Technology. Final Summary Report.

ERIC Educational Resources Information Center

Rensselaer Polytechnic Inst., Troy, NY. Telecommunications Research Center.

Technological alternatives in the evolution of present cable television systems into broadband communication networks (BCN) were assessed. Cost estimates were made for alternatives, and the impact of alternatives on BCN development was investigated. An historical study of cable television technology was made which related it to other…

VOCATIONAL EDUCATION INFORMATION SYSTEM. FINAL REPORT.

ERIC Educational Resources Information Center

ZWICKEL, I.; AND OTHERS

STATE- AND FEDERAL-LEVEL DESIGN SPECIFICATIONS WERE DEVELOPED FOR A SYSTEM CAPABLE OF COLLECTING AND REDUCING NATIONWIDE STATISTICAL DATA ON VOCATIONAL EDUCATION. THESE SPECIFICATIONS WERE EXPECTED TO PROVIDE THE BASIS FOR THE ADOPTION BY ALL STATES OF AN INFORMATION REPORTING SYSTEM THAT WOULD MEET BOTH PRESENT AND FUTURE FEDERAL REPORTING…

Robotics: Past, Present, and Future.

ERIC Educational Resources Information Center

Dunne, Maurice J.

Robots are finally receiving wide-spread attention as a means to realize the goal of automating factories. In the 1960's robot use was limited by unfavorable acquisition and operating costs and the affordable control technology limiting applications to relatively simple jobs. During the 1970's productivity of manufacturing organizations declined…

Kohlberg's Moral Development Model: Cohort Influences on Validity.

ERIC Educational Resources Information Center

Bechtel, Ashleah

An overview of Kohlberg's theory of moral development is presented; three interviews regarding the theory are reported, and the author's own moral development is compared to the model; finally, a critique of the theory is addressed along with recommendations for future enhancement. Lawrence Kohlberg's model of moral development, also referred to…

Analysis of regional natural flow for evaluation of flood risk according to RCP climate change scenarios

NASA Astrophysics Data System (ADS)

Lee, J. Y.; Chae, B. S.; Wi, S.; KIm, T. W.

2017-12-01

Various climate change scenarios expect the rainfall in South Korea to increase by 3-10% in the future. The future increased rainfall has significant effect on the frequency of flood in future as well. This study analyzed the probability of future flood to investigate the stability of existing and new installed hydraulic structures and the possibility of increasing flood damage in mid-sized watersheds in South Korea. To achieve this goal, we first clarified the relationship between flood quantiles acquired from the flood-frequency analysis (FFA) and design rainfall-runoff analysis (DRRA) in gauged watersheds. Then, after synthetically generating the regional natural flow data according to RCP climate change scenarios, we developed mathematical formulas to estimate future flood quantiles based on the regression between DRRA and FFA incorporated with regional natural flows in unguaged watersheds. Finally, we developed a flood risk map to investigate the change of flood risk in terms of the return period for the past, present, and future. The results identified that the future flood quantiles and risks would increase in accordance with the RCP climate change scenarios. Because the regional flood risk was identified to increase in future comparing with the present status, comprehensive flood control will be needed to cope with extreme floods in future.

IPG Power Grid Overview

NASA Technical Reports Server (NTRS)

Hinke, Thomas

2003-01-01

This presentation will describe what is meant by grids and then cover the current state of the IPG. This will include an overview of the middleware that is key to the operation of the grid. The presentation will then describe some of the future directions that are planned for the IPG. Finally the presentation will conclude with a brief overview of the Global Grid Forum, which is a key activity that will contribute to the successful availability of grid components.

Future flavour physics experiments

PubMed Central

2015-01-01

The current status of flavour physics and the prospects for present and future experiments will be reviewed. Measurements in B‐physics, in which sensitive probes of new physics are the CKM angle γ, the Bs mixing phase ϕs, and the branching ratios of the rare decays B(s)0→μ+μ− , will be highlighted. Topics in charm and kaon physics, in which the measurements of ACP and the branching ratios of the rare decays K→πνν¯ are key measurements, will be discussed. Finally the complementarity of the future heavy flavour experiments, the LHCb upgrade and Belle‐II, will be summarised. PMID:26877543

Evaluation of Future Internet Technologies for Processing and Distribution of Satellite Imagery

NASA Astrophysics Data System (ADS)

Becedas, J.; Perez, R.; Gonzalez, G.; Alvarez, J.; Garcia, F.; Maldonado, F.; Sucari, A.; Garcia, J.

2015-04-01

Satellite imagery data centres are designed to operate a defined number of satellites. For instance, difficulties when new satellites have to be incorporated in the system appear. This occurs because traditional infrastructures are neither flexible nor scalable. With the appearance of Future Internet technologies new solutions can be provided to manage large and variable amounts of data on demand. These technologies optimize resources and facilitate the appearance of new applications and services in the traditional Earth Observation (EO) market. The use of Future Internet technologies for the EO sector were validated with the GEO-Cloud experiment, part of the Fed4FIRE FP7 European project. This work presents the final results of the project, in which a constellation of satellites records the whole Earth surface on a daily basis. The satellite imagery is downloaded into a distributed network of ground stations and ingested in a cloud infrastructure, where the data is processed, stored, archived and distributed to the end users. The processing and transfer times inside the cloud, workload of the processors, automatic cataloguing and accessibility through the Internet are evaluated to validate if Future Internet technologies present advantages over traditional methods. Applicability of these technologies is evaluated to provide high added value services. Finally, the advantages of using federated testbeds to carry out large scale, industry driven experiments are analysed evaluating the feasibility of an experiment developed in the European infrastructure Fed4FIRE and its migration to a commercial cloud: SoftLayer, an IBM Company.

NASA/USRA advanced design program

NASA Technical Reports Server (NTRS)

1992-01-01

This report analyzes and presents a preliminary design for an experimental hypersonic vehicle. This plane will have a cruise speed of Mach 12 for one minute at an altitude of 120,000 feet. The major design areas of aerodynamics, propulsion, and weights are discussed in depth. An elementary analysis of thermal protection, trajectory, and cost is also presented. Finally, a discussion of future plans and recommendations is given, and overall conclusions are drawn.

Key issues in space nuclear power challenges for the future

NASA Technical Reports Server (NTRS)

Brandhorst, Henry W., Jr.

1991-01-01

The future appears rich in missions that will extend the frontiers of knowledge, human presence in space, and opportunities for profitable commerce. Key to the success of these ventures is the availability of plentiful, cost effective electric power and assured, low cost access to space. While forecasts of space power needs are problematic, an assessment of future needs based on terrestrial experience has been made. These needs fall into three broad categories: survival, self sufficiency, and industrialization. The cost of delivering payloads to orbital locations from LEO to Mars has been determined and future launch cost reductions projected. From these factors, then, projections of the performance necessary for future solar and nuclear space power options has been made. These goals are largely dependent upon orbital location and energy storage needs. Finally the cost of present space power systems has been determined and projections made for future systems.

Machine detector interface studies: Layout and synchrotron radiation estimate in the future circular collider interaction region

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boscolo, Manuela; Burkhardt, Helmut; Sullivan, Michael

The interaction region layout for the e +e – future circular collider FCC-ee is presented together with a preliminary estimate of synchrotron radiation that affects this region. We describe in this paper the main guidelines of this design and the estimate of synchrotron radiation coming from the last bending magnets and from the final focus quadrupoles, with the software tools developed for this purpose. Here, the design follows the asymmetric optics layout as far as incoming bend radiation is concerned with the maximum foreseen beam energy of 175 GeV and we present a feasible initial layout with an indication ofmore » tolerable synchrotron radiation.« less

Social Neuroscience and Hyperscanning Techniques: Past, Present and Future

PubMed Central

Babiloni, Fabio; Astolfi, Laura

2012-01-01

This paper reviews the published literature on the hyperscanning methodologies using hemodynamic or neuro-electric modalities. In particular, we describe how different brain recording devices have been employed in different experimental paradigms to gain information about the subtle nature of human interactions. This review also included papers based on single-subject recordings in which a correlation was found between the activities of different (non-simultaneously recorded) participants in the experiment. The descriptions begin with the methodological issues related to the simultaneous measurements and the descriptions of the results generated by such approaches will follow. Finally, a discussion of the possible future uses of such new approaches to explore human social interactions will be presented. PMID:22917915

Machine detector interface studies: Layout and synchrotron radiation estimate in the future circular collider interaction region

DOE PAGES

Boscolo, Manuela; Burkhardt, Helmut; Sullivan, Michael

2017-01-27

The interaction region layout for the e +e – future circular collider FCC-ee is presented together with a preliminary estimate of synchrotron radiation that affects this region. We describe in this paper the main guidelines of this design and the estimate of synchrotron radiation coming from the last bending magnets and from the final focus quadrupoles, with the software tools developed for this purpose. Here, the design follows the asymmetric optics layout as far as incoming bend radiation is concerned with the maximum foreseen beam energy of 175 GeV and we present a feasible initial layout with an indication ofmore » tolerable synchrotron radiation.« less

NXE pellicle: development update

NASA Astrophysics Data System (ADS)

Brouns, Derk; Bendiksen, Aage; Broman, Par; Casimiri, Eric; Colsters, Paul; de Graaf, Dennis; Harrold, Hilary; Hennus, Piet; Janssen, Paul; Kramer, Ronald; Kruizinga, Matthias; Kuntzel, Henk; Lafarre, Raymond; Mancuso, Andrea; Ockwell, David; Smith, Daniel; van de Weg, David; Wiley, Jim

2016-09-01

ASML introduced the NXE pellicle concept, a removable pellicle solution that is compatible with current and future patterned mask inspection methods. We will present results of how we have taken the idea from concept to a demonstrated solution enabling the use of EUV pellicle by the industry for high volume manufacturing. We will update on the development of the next generation of pellicle films with higher power capability. Further, we will provide an update on top level requirements for pellicles and external interface requirements needed to support NXE pellicle adoption at a mask shop. Finally, we will present ASML's pellicle handling equipment to enable pellicle use at mask shops and our NXE pellicle roadmap outlining future improvements.

Being there: the library as place.

PubMed

Weise, Frieda

2004-01-01

The value of the library as place is examined in this Janet Doe Lecture. The lecture, which is intended to focus on the history or philosophy of health sciences librarianship, presents an overview of the library as a place in society from ancient times to the present. The impact of information technology and changes in the methods of scholarly publication from print to digital are addressed as well as the role of the library as the repository of the written historical record of cultures. Functions and services of libraries are discussed in light of the physical library facility of the future. Finally, librarians are asked to remember the enduring values of librarianship in planning libraries of the future.

Health psychology in Ghana: A review of the multidisciplinary origins of a young sub-field and its future prospects.

PubMed

de-Graft Aikins, Ama

2018-03-01

This article presents a historical overview of psychology applied to health and health psychology in Ghana. A brief history of health, illness and healthcare in Ghana is introduced. Then, the history of psychology in Ghana is presented, with signposts of the major turns in the field in relation to psychology and other disciplines applied to health and the emergence of health psychology as a sub-field. Selected health psychology studies are reviewed to highlight ideological trends in the field. Finally, future prospects are considered in terms of how the sub-field can transition into an established critical field with unique contributions to make to global health psychology.

Being there: the library as place*

PubMed Central

Weise, Frieda

2004-01-01

The value of the library as place is examined in this Janet Doe Lecture. The lecture, which is intended to focus on the history or philosophy of health sciences librarianship, presents an overview of the library as a place in society from ancient times to the present. The impact of information technology and changes in the methods of scholarly publication from print to digital are addressed as well as the role of the library as the repository of the written historical record of cultures. Functions and services of libraries are discussed in light of the physical library facility of the future. Finally, librarians are asked to remember the enduring values of librarianship in planning libraries of the future. PMID:14762459

Investigation of free-forced convection flows in cavity-type receivers. Final yearly report, 1979-1980

DOE Office of Scientific and Technical Information (OSTI.GOV)

Humphrey, J.A.C.

1982-01-01

A summary is provided of the first of three years of experimental and theoretical research on free-forced convection flows in cavity-type solar receivers. New experimental and theoretical results are presented and discussed. The implication of these findings, with respect to the future thrust of the research program, is clarified as well as is possible at the present time. Following various related conclusions a summary and tentative schedule of work projected for year two of research are presented.

17 CFR 171.21 - Notice of final decision.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Futures Association shall promptly serve all parties, as well as the Proceedings Clerk and the Secretary... decision issued by the National Futures Association. (b) Content of the notice. At a minimum, the notice... notice. (1) If the National Futures Association issues a notice of a final decision subject to these...

17 CFR 171.21 - Notice of final decision.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Futures Association shall promptly serve all parties, as well as the Proceedings Clerk and the Secretary... decision issued by the National Futures Association. (b) Content of the notice. At a minimum, the notice... notice. (1) If the National Futures Association issues a notice of a final decision subject to these...

17 CFR 171.21 - Notice of final decision.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Futures Association shall promptly serve all parties, as well as the Proceedings Clerk and the Secretary... decision issued by the National Futures Association. (b) Content of the notice. At a minimum, the notice... notice. (1) If the National Futures Association issues a notice of a final decision subject to these...

17 CFR 171.21 - Notice of final decision.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Futures Association shall promptly serve all parties, as well as the Proceedings Clerk and the Secretary... decision issued by the National Futures Association. (b) Content of the notice. At a minimum, the notice... notice. (1) If the National Futures Association issues a notice of a final decision subject to these...

17 CFR 171.21 - Notice of final decision.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Futures Association shall promptly serve all parties, as well as the Proceedings Clerk and the Secretary... decision issued by the National Futures Association. (b) Content of the notice. At a minimum, the notice... notice. (1) If the National Futures Association issues a notice of a final decision subject to these...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Korte, Andrew R

This thesis presents efforts to improve the methodology of matrix-assisted laser desorption ionization-mass spectrometry imaging (MALDI-MSI) as a method for analysis of metabolites from plant tissue samples. The first chapter consists of a general introduction to the technique of MALDI-MSI, and the sixth and final chapter provides a brief summary and an outlook on future work.

40 CFR Appendix A to Subpart K of... - Criteria for evaluating a State's proposed NEPA-Like process

Code of Federal Regulations, 2014 CFR

2014-07-01

... SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2) A...) Present and future conditions; (5) Land use and other social parameters including recreation and open... (residential, commercial, institutional and industrial) within the project study area; and (8) Other...

40 CFR Appendix A to Subpart K of... - Criteria for evaluating a State's proposed NEPA-Like process

Code of Federal Regulations, 2011 CFR

2011-07-01

... SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2) A...) Present and future conditions; (5) Land use and other social parameters including recreation and open... (residential, commercial, institutional and industrial) within the project study area; and (8) Other...

40 CFR Appendix A to Subpart L of... - Criteria for Evaluating a State's Proposed NEPA-Like Process

Code of Federal Regulations, 2013 CFR

2013-07-01

... the SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2... impacts; (4) Present and future conditions; (5) Land use and other social parameters including relevant... (residential, commercial, institutional, and industrial) within the project study area; and (8) Other...

40 CFR Appendix A to Subpart K of... - Criteria for evaluating a State's proposed NEPA-Like process

Code of Federal Regulations, 2012 CFR

2012-07-01

... SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2) A...) Present and future conditions; (5) Land use and other social parameters including recreation and open... (residential, commercial, institutional and industrial) within the project study area; and (8) Other...

40 CFR Appendix A to Subpart K of... - Criteria for evaluating a State's proposed NEPA-Like process

Code of Federal Regulations, 2010 CFR

2010-07-01

... SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2) A...) Present and future conditions; (5) Land use and other social parameters including recreation and open... (residential, commercial, institutional and industrial) within the project study area; and (8) Other...

40 CFR Appendix A to Subpart K of... - Criteria for evaluating a State's proposed NEPA-Like process

Code of Federal Regulations, 2013 CFR

2013-07-01

... SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2) A...) Present and future conditions; (5) Land use and other social parameters including recreation and open... (residential, commercial, institutional and industrial) within the project study area; and (8) Other...

40 CFR Appendix A to Subpart L of... - Criteria for Evaluating a State's Proposed NEPA-Like Process

Code of Federal Regulations, 2014 CFR

2014-07-01

... the SERP will adequately consider: (1) Designation of a study area comparable to the final system; (2... impacts; (4) Present and future conditions; (5) Land use and other social parameters including relevant... (residential, commercial, institutional, and industrial) within the project study area; and (8) Other...

Assessment of Training Needs for Arizona Student Financial Aid Practitioners. Final Report.

ERIC Educational Resources Information Center

Fenske, Robert H.

The present and future training needs of financial aid practitioners (financial aid officers, counselors, and support staff personnel) at Arizona colleges and government agencies were assessed. Attention was directed to the literature on training and programs for financial aid practitioners, as well as the possibilities of developing a…

Parent Depression and Child Anxiety: An Overview of the Literature with Clinical Implications

ERIC Educational Resources Information Center

Colletti, Christina J. M.; Forehand, Rex; Garai, Emily; Rakow, Aaron; McKee, Laura; Fear, Jessica M.; Compas, Bruce E.

2009-01-01

The association of parental depression with child anxiety has received relatively little attention in the literature. In this paper we initially present several reasons for examining this relationship. We then summarize the empirical support for a link between these two variables. Finally, we discuss directions for future research and clinical…

Safety Tips: Academic Laboratory Waste Disposal: Yes, You Can Get Rid of that Stuff Legally!

ERIC Educational Resources Information Center

Young, Jay A.

1983-01-01

Discusses three methods for removing wastes from educational laboratories. These include paying someone with Environmental Protection Agency (EPA) permits, doing part of the work before an EPA contractor carries out final steps, or reducing magnitude of future disposal problems by changing present laboratory procedures. Includes comments on…

Workshop of the Experimental Project on Programmed Instruction in Asia. Final Report.

ERIC Educational Resources Information Center

United Nations Educational, Scientific, and Cultural Organization, Paris (France).

The present situation and future trends of programed learning in Ceylon, Republic of China, India, Indonesia, Japan, Republic of Korea, Malaysia, Pakistan, Philippines, Singapore, Thailand, and Republic of Viet-Nam are described by the Workshop participants. Some of the unique features of programed learning are examined with respect to the…

Harnessing Light: Capitalizing on Optical Science Trends and Challenges for Future Research. Final Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Svedberg, Erik

2014-02-06

The committee has during the earlier period finalized their work on the report, Optics and Photonics: Essential Technologies for Our Nation (2013) . The report did undergo review and initial editorial processing. The NRC released a pre-publication report on August 13, 2012. A final report is now available. The study director has been able to practice his skills in running a national academies committee. From a research perspective the grant has generated a report with recommendations to the government. The work itself is the meetings where the committee convened to hear presenters and to discuss the status of optics andmore » photonics as well as writing the report.« less

STS-3 Induced Environment Contamination Monitor (IECM): Quick-look report

NASA Technical Reports Server (NTRS)

Miller, E. R. (Editor); Fountain, J. A. (Editor)

1982-01-01

The STS-3/Induced Environment Contamination Monitor (IECM) mission is described. The IECM system performance is discussed, and IECM mission time events are briefly described. Quick look analyses are presented for each of the 10 instruments comprising the IECM on the flight of STS-3. Finally, a short summary is presented and plans are discussed for future IECM flights, and opportunities for direct mapping of Orbiter effluents using the Remote manipulator System.

Comparison of radar and infrared distance sensors for intelligent cruise control systems

NASA Astrophysics Data System (ADS)

Hoess, Alfred; Hosp, Werner; Rauner, Hans

1995-09-01

In this paper, infrared distance sensors are compared regarding technology, environmental, and practical aspects. Different methods for obtaining lateral resolution and covering the required detection range are presented for both sensor technologies. Possible positions for sensor installation at the test vehicle have been tested. Experimental results regarding cleaning devices and other environmental problems are presented. Finally, future aspects, e.g. speed over ground measurements or technological steps are discussed.

A multichannel fiber optic photometer present performance and future developments

NASA Technical Reports Server (NTRS)

Barwig, H.; Schoembs, R.; Huber, G.

1988-01-01

A three channel photometer for simultaneous multicolor observations was designed with the aim of making possible highly efficient photometry of fast variable objects like cataclysmic variables. Experiences with this instrument over a period of three years are presented. Aspects of the special techniques applied are discussed with respect to high precision photometry. In particular, the use of fiber optics is critically analyzed. Finally, the development of a new photometer concept is discussed.

Creating new futures in nursing education: envisioning the evolution of e-nursing education.

PubMed

Neuman, Lois H

2006-01-01

This article discusses the explosion of technology and its impact on nursing education in the face of a nurse educator shortage. An attempt is made to answer the following questions:What incremental changes in technology do we have now? How do we envision technology being used in the future? Four scenarios of nontraditional approaches to nursing education are presented. They touch on the delivery of education with increased technology and universal access; the teacher as educator/mentor/coach; the product, including testing, outcomes, competencies, and process; and attracting and keeping human attention. The final section focuses on issues to consider as nurse leaders and educators bring nursing education into the future.

Data Acquisition and Mass Storage

NASA Astrophysics Data System (ADS)

Vande Vyvre, P.

2004-08-01

The experiments performed at supercolliders will constitute a new challenge in several disciplines of High Energy Physics and Information Technology. This will definitely be the case for data acquisition and mass storage. The microelectronics, communication, and computing industries are maintaining an exponential increase of the performance of their products. The market of commodity products remains the largest and the most competitive market of technology products. This constitutes a strong incentive to use these commodity products extensively as components to build the data acquisition and computing infrastructures of the future generation of experiments. The present generation of experiments in Europe and in the US already constitutes an important step in this direction. The experience acquired in the design and the construction of the present experiments has to be complemented by a large R&D effort executed with good awareness of industry developments. The future experiments will also be expected to follow major trends of our present world: deliver physics results faster and become more and more visible and accessible. The present evolution of the technologies and the burgeoning of GRID projects indicate that these trends will be made possible. This paper includes a brief overview of the technologies currently used for the different tasks of the experimental data chain: data acquisition, selection, storage, processing, and analysis. The major trends of the computing and networking technologies are then indicated with particular attention paid to their influence on the future experiments. Finally, the vision of future data acquisition and processing systems and their promise for future supercolliders is presented.

A study of current world telecommunications and a projection of the future

NASA Astrophysics Data System (ADS)

Karageorgis, Costas

1992-09-01

Telecommunications today are important factors in economic and social progress. The last decades of the 20th century and the early years of the 21st have been characterized as the Information Age. Telecommunications, the movement of information through distances, is absolutely critical to the economic and military survival of nations. This thesis is an attempt to predict the future of telecommunications, by studying and analyzing the past and present. First it examines the meaning of telecommunications today and some basics of information transmission. The current status of telecommunications is then presented, by examining the regional profiles as they are divided by the International Telecommunications Union. A number of statistical studies are given, which present a thorough picture of current world telecommunications. In an effort to predict future industry trends, the competition among the three largest telecommunications markets, U.S.A., Japan and the European Community, is also considered by looking at their present telecommunications industry, the efforts they make to improve their technology, and their plans for future investment. Finally, some major technological trends including BISDN, the use of fiber technology in the communications loop, and the use of solitons are examined. The new Metropolitan Area Network Protocol, FDDI-2 is also reviewed.

Living in the Past, Present, and Future: Measuring Temporal Orientation With Language.

PubMed

Park, Gregory; Schwartz, H Andrew; Sap, Maarten; Kern, Margaret L; Weingarten, Evan; Eichstaedt, Johannes C; Berger, Jonah; Stillwell, David J; Kosinski, Michal; Ungar, Lyle H; Seligman, Martin E P

2017-04-01

Temporal orientation refers to individual differences in the relative emphasis one places on the past, present, or future, and it is related to academic, financial, and health outcomes. We propose and evaluate a method for automatically measuring temporal orientation through language expressed on social media. Judges rated the temporal orientation of 4,302 social media messages. We trained a classifier based on these ratings, which could accurately predict the temporal orientation of new messages in a separate validation set (accuracy/mean sensitivity = .72; mean specificity = .77). We used the classifier to automatically classify 1.3 million messages written by 5,372 participants (50% female; ages 13-48). Finally, we tested whether individual differences in past, present, and future orientation differentially related to gender, age, Big Five personality, satisfaction with life, and depressive symptoms. Temporal orientations exhibit several expected correlations with age, gender, and Big Five personality. More future-oriented people were older, more likely to be female, more conscientious, less impulsive, less depressed, and more satisfied with life; present orientation showed the opposite pattern. Language-based assessments can complement and extend existing measures of temporal orientation, providing an alternative approach and additional insights into language and personality relationships. © 2015 Wiley Periodicals, Inc.

Back to the future: the role of the ISS and future space stations in planetary exploration.

NASA Astrophysics Data System (ADS)

Muller, Christian; Moreau, Didier

2010-05-01

Space stations as stepping stones to planets appear already in the1954 Disney-von Braun anticipation TV show but the first study with a specific planetary scientific objective was the ANTEUS project of 1978. This station was an evolution of SPACELAB hardware and was designed to analyse Mars samples with better equipment than the laboratory of the VIKING landers. It would have played the role of the reception facility present in the current studies of Mars sample return, after analysis, the "safe" samples would have been returned to earth by the space shuttle. This study was followed by the flights of SPACELAB and MIR. Finally after 35 years of development, the International Space Station reaches its final configuration in 2010. Recent developments of the international agreement between the space agencies indicate a life extending to 2025, it is already part of the exploration programme as its crews prepare the long cruise flights and missions to the exploration targets. It is now time to envisage also the use of this stable 350 tons spacecraft for planetary and space sciences. Planetary telescopes are an obvious application; the present SOLAR payload on COLUMBUS is an opportunity to use the target pointing capabilities from the ISS. The current exposure facilities are also preparing future planetary protection procedures. Other applications have already been previously considered as experimental collision and impact studies in both space vacuum and microgravity. Future space stations at the Lagrange points could simultaneously combine unique observation platforms with an actual intermediate stepping stone to Mars.

Key issues in space nuclear power

NASA Technical Reports Server (NTRS)

Brandhorst, Henry W.

1991-01-01

The future appears rich in missions that will extend the frontiers of knowledge, human presence in space, and opportunities for profitable commerce. Key to the success of these ventures is the availability of plentiful, cost effective electric power and assured, low cost access to space. While forecasts of space power needs are problematic, an assessment of future needs based on terrestrial experience has been made. These needs fall into three broad categories: survival, self sufficiency, and industrialization. The cost of delivering payloads to orbital locations from LEO to Mars has been determined and future launch cost reductions projected. From these factors, then, projections of the performance necessary for future solar and nuclear space power options has been made. These goals are largely dependent upon orbital location and energy storage needs. Finally the cost of present space power systems has been determined and projections made for future systems.

Directions for the Future: Federal Programs in Education Designed to Improve International Understanding and Cooperation. Final Report.

ERIC Educational Resources Information Center

Marvel, William W.

The central focus of the report is on the changes, adjustments, and consolidation necessary to achieve national goals through international education. Recommendations pertaining to the federal agencies and activities in international education are presented as sets of options which seek to: (1) define the basis for evaluating the federal…

Forecasts of Selected Social Indicators of Educational Outcomes and Recommended Policy Changes. (Final Report).

ERIC Educational Resources Information Center

Collazo, Andres; And Others

This report has three objectives: (1) to identify social indicators relating to policy concerns of the legislature, state board of education, and commissioner of education; (2) to predict the future status of selected social indicators, using the assumption that present policies will be continued; and (3) to recommend policy changes for achieving…

The Work Orientations of Australian University Students

ERIC Educational Resources Information Center

Taylor, Jeannette; Pick, David

2008-01-01

It is the aim of this paper to provide a better understanding of how university students in Australia are preparing for their future work in the labour market through their work orientations. It draws upon a survey of over 300 final-year undergraduates to present their rationales for engaging in paid work, and their preferences for different job…

President's Task Force on Communications Policy. Staff Paper Five. Part II.

ERIC Educational Resources Information Center

President's Task Force on Communications Policy, Washington, DC.

The second part of a staff paper to the President's Task Force on Communications Policy dealing with the domestic telecommunications carrier industry consists of the final two appendices. In the first, the history, structure, present services, and future plans of the Western Union Telegraph Company are discussed. Evidence is given that by allowing…

Academic Freedom and Student Grading in Greek Higher Education

ERIC Educational Resources Information Center

Papadimitriou, Antigoni

2011-01-01

The issue of who has the final say on academic standards (grading), academics or managers, has hitherto not arisen in Greece. Professors entitled to research, to teach and to inquire is a freedom expressed by the Greek Constitution. This article presents a contemporary view and raises concerns about the future and the longevity of academic freedom…

The Future of Work: Insights, Views, Prospects. Basis-Info: Social Policy. IN Press.

ERIC Educational Resources Information Center

Bechtel, Michael

Young people must prepare themselves for lifelong learning and frequent job changes. Optimists predict a new world of work with many creative, interesting, satisfying jobs; pessimists believe society will finally run out of work and foresee unemployment and social downgrading for a majority of people. There are indications at present of both…

75 FR 66184 - The Future of Aviation Advisory Committee (FAAC) Subcommittee on Financing; Notice of Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-27

..., and sufficient level of funding for our aviation system and make recommendations to the Secretary for... recommendations to the Secretary of Transportation to ensure the competitiveness of the U.S. aviation industry and... recommendations for presentation at the final meeting of the FAAC on December 15, 2010. Registration The meeting...

Overview of computational structural methods for modern military aircraft

NASA Technical Reports Server (NTRS)

Kudva, J. N.

1992-01-01

Computational structural methods are essential for designing modern military aircraft. This briefing deals with computational structural methods (CSM) currently used. First a brief summary of modern day aircraft structural design procedures is presented. Following this, several ongoing CSM related projects at Northrop are discussed. Finally, shortcomings in this area, future requirements, and summary remarks are given.

[Research progress of thermal control system for extravehicular activity space suit].

PubMed

Wu, Z Q; Shen, L P; Yuan, X G

1999-08-01

New research progress of thermal control system for oversea Extravehicular Activity (EVA) space suit is presented. Characteristics of several thermal control systems are analyzed in detail. Some research tendencies and problems are discussed, which are worthwhile to be specially noted. Finally, author's opinion about thermal control system in the future is put forward.

Microfluidics and Raman microscopy: current applications and future challenges.

PubMed

Chrimes, Adam F; Khoshmanesh, Khashayar; Stoddart, Paul R; Mitchell, Arnan; Kalantar-Zadeh, Kourosh

2013-07-07

Raman microscopy systems are becoming increasingly widespread and accessible for characterising chemical species. Microfluidic systems are also progressively finding their way into real world applications. Therefore, it is anticipated that the integration of Raman systems with microfluidics will become increasingly attractive and practical. This review aims to provide an overview of Raman microscopy-microfluidics integrated systems for researchers who are actively interested in utilising these tools. The fundamental principles and application strengths of Raman microscopy are discussed in the context of microfluidics. Various configurations of microfluidics that incorporate Raman microscopy methods are presented, with applications highlighted. Data analysis methods are discussed, with a focus on assisting the interpretation of Raman-microfluidics data from complex samples. Finally, possible future directions of Raman-microfluidic systems are presented.

HSR Model Deformation Measurements from Subsonic to Supersonic Speeds

NASA Technical Reports Server (NTRS)

Burner, A. W.; Erickson, G. E.; Goodman, W. L.; Fleming, G. A.

1999-01-01

This paper describes the video model deformation technique (VMD) used at five NASA facilities and the projection moire interferometry (PMI) technique used at two NASA facilities. Comparisons between the two techniques for model deformation measurements are provided. Facilities at NASA-Ames and NASA-Langley where deformation measurements have been made are presented. Examples of HSR model deformation measurements from the Langley Unitary Wind Tunnel, Langley 16-foot Transonic Wind Tunnel, and the Ames 12-foot Pressure Tunnel are presented. A study to improve and develop new targeting schemes at the National Transonic Facility is also described. The consideration of milled targets for future HSR models is recommended when deformation measurements are expected to be required. Finally, future development work for VMD and PMI is addressed.

Solar heating and cooling of buildings (SHACOB) commercialization report: options and strategies. Part A. Volume II. Technical report. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The national and regional perspectives for SHACOB are presented. An overview is given of the participants in SHACOB commercialization. Economic, institutional, legal, and other barriers constraining commercialization are discussed. Various analytical models are examined which project the future extent of SHACOB use or market penetration and future SHACOB to US energy supplies under alternative government policies. The results for the baseline case (no further government action, of several market penetration models are presented. Possible ways to overcome each of the barriers are presented. Qualitative analyses are given for the various incentives. Each incentive is examined to assess its impact onmore » barriers to SHACOB commercialization and its impact on various income and interest groups. Individual incentives are compared and combined into alternative policy strategies and options. (MHR)« less

Medial Temporal Lobe Damage Causes Deficits in Episodic Memory and Episodic Future Thinking Not Attributable to Deficits in Narrative Construction

PubMed Central

Race, Elizabeth; Keane, Margaret M.; Verfaellie, Mieke

2015-01-01

The medial temporal lobe (MTL) makes critical contributions to episodic memory, but its contributions to episodic future thinking remain a matter of debate. By one view, imagining future events relies on MTL mechanisms that also support memory for past events. Alternatively, it has recently been suggested that future thinking is independent of MTL-mediated processes and can be supported by regions outside the MTL. The current study investigated the nature and necessity of MTL involvement in imagining the future and tested the novel hypothesis that the MTL contributes to future thinking by supporting online binding processes related to narrative construction. Human amnesic patients with well-characterized MTL damage and healthy controls constructed narratives about (a) future events, (b) past events, and (c) visually-presented pictures. While all three tasks place similar demands on narrative construction, only the past and future conditions require memory/future thinking to mentally generate relevant narrative information. Patients produced impoverished descriptions of both past and future events but were unimpaired at producing detailed picture narratives. In addition, future-thinking performance positively correlated with episodic memory performance but did not correlate with picture narrative performance. Finally, future-thinking impairments were present when MTL lesions were restricted to the hippocampus and did not depend on the presence of neural damage outside the MTL. These results indicate that the ability to generate and maintain a detailed narrative is preserved in amnesia and suggest that a common MTL mechanism supports both episodic memory and episodic future thinking. PMID:21753003

Medial temporal lobe damage causes deficits in episodic memory and episodic future thinking not attributable to deficits in narrative construction.

PubMed

Race, Elizabeth; Keane, Margaret M; Verfaellie, Mieke

2011-07-13

The medial temporal lobe (MTL) makes critical contributions to episodic memory, but its contributions to episodic future thinking remain a matter of debate. By one view, imagining future events relies on MTL mechanisms that also support memory for past events. Alternatively, it has recently been suggested that future thinking is independent of MTL-mediated processes and can be supported by regions outside the MTL. The current study investigated the nature and necessity of MTL involvement in imagining the future and tested the novel hypothesis that the MTL contributes to future thinking by supporting online binding processes related to narrative construction. Human amnesic patients with well characterized MTL damage and healthy controls constructed narratives about (1) future events, (2) past events, and (3) visually presented pictures. While all three tasks place similar demands on narrative construction, only the past and future conditions require memory/future thinking to mentally generate relevant narrative information. Patients produced impoverished descriptions of both past and future events but were unimpaired at producing detailed picture narratives. In addition, future-thinking performance positively correlated with episodic memory performance but did not correlate with picture narrative performance. Finally, future-thinking impairments were present when MTL lesions were restricted to the hippocampus and did not depend on the presence of neural damage outside the MTL. These results indicate that the ability to generate and maintain a detailed narrative is preserved in amnesia and suggest that a common MTL mechanism supports both episodic memory and episodic future thinking.

CERN and 60 years of science for peace

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heuer, Rolf-Dieter, E-mail: Rolf.Heuer@cern.ch

2015-02-24

This paper presents CERN as it celebrates its 60{sup th} Anniversary since its founding. The presentation first discusses the mission of CERN and its role as an inter-governmental Organization. The paper also reviews aspects of the particle physics research programme, looking at both current and future accelerator-based facilities at the high-energy and intensity frontiers. Finally, the paper considers issues beyond fundamental research, such as capacity-building and the interface between Art and Science.

An optical profilometer for spatial characterization of three-dimensional surfaces

NASA Technical Reports Server (NTRS)

Kelly, W. L., IV; Burcher, E. E.; Skolaut, M. W., Jr.

1977-01-01

The design concept and system operation of an optical profilometer are discussed, and a preliminary evaluation of a breadboard system is presented to demonstrate the feasibility of the optical profilometer technique. Measurement results are presented for several test surfaces; and to illustrate a typical application, results are shown for a cleft palate cast used by dental surgeons. Finally, recommendations are made for future development of the optical profilometer technique for specific engineering or scientific applications.

Precise time technology for selected Air Force systems: Present status and future requirements

NASA Technical Reports Server (NTRS)

Yannoni, N. F.

1981-01-01

Precise time and time interval (PTTI) technology is becoming increasingly significant to Air Force operations as digital techniques find expanded utility in military missions. Timing has a key role in the function as well as in navigation. A survey of the PTTI needs of several Air Force systems is presented. Current technology supporting these needs was reviewed and new requirements are emphasized for systems as they transfer from initial development to final operational deployment.

High-level specification of a proposed information architecture for support of a bioterrorism early-warning system.

PubMed

Berkowitz, Murray R

2013-01-01

Current information systems for use in detecting bioterrorist attacks lack a consistent, overarching information architecture. An overview of the use of biological agents as weapons during a bioterrorist attack is presented. Proposed are the design, development, and implementation of a medical informatics system to mine pertinent databases, retrieve relevant data, invoke appropriate biostatistical and epidemiological software packages, and automatically analyze these data. The top-level information architecture is presented. Systems requirements and functional specifications for this level are presented. Finally, future studies are identified.

Situation-specific theories from the middle-range transitions theory.

PubMed

Im, Eun-Ok

2014-01-01

The purpose of this article was to analyze the theory development process of the situation-specific theories that were derived from the middle-range transitions theory. This analysis aims to provide directions for future development of situation-specific theories. First, transitions theory is concisely described with its history, goal, and major concepts. Then, the approach that was used to retrieve the situation-specific theories derived from transitions theory is described. Next, an analysis of 6 situation-specific theories is presented. Finally, 4 themes reflecting commonalities and variances in the theory development process are discussed with implications for future theoretical development.

An update on X-ray reflection gratings developed for future missions

NASA Astrophysics Data System (ADS)

Miles, Drew

2018-01-01

X-ray reflection gratings are a key technology being studied for future X-ray spectroscopy missions, including the Lynx X-ray mission under consideration for the 2020 Decadal Survey. We present an update on the status of X-ray reflection gratings being developed at Penn State University, including current fabrication techniques and mass-replication processes and the latest diffraction efficiency results and resolving power measurements. Individual off-plane X-ray reflection gratings have exceeded the current Lynx requirements for both effective area and resolving power. Finally, we discuss internal projects that will advance the technology readiness level of these gratings.

NASA and COTS Electronics: Past Approach and Successes - Future Considerations

NASA Technical Reports Server (NTRS)

LaBel, Kenneth A.

2018-01-01

NASA has a long history of using commercial grade electronics in space. In this talk, a brief history of NASAâ's trends and approaches to commercial grade electronics focusing on processing and memory systems will be presented. This will include providing summary information on the space hazards to electronics as well as NASA mission trade space. We will also discuss developing recommendations for risk management approaches to Electrical, Electronic and Electromechanical (EEE) parts and reliability in space. The final portion of the talk will discuss emerging aerospace trends and the future for Commercial Off The Shelf (COTS) usage.

Management of Knowledge Representation Standards Activities

NASA Technical Reports Server (NTRS)

Patil, Ramesh S. (Principal Investigator)

1993-01-01

This report describes the efforts undertaken over the last two years to identify the issues underlying the current difficulties in sharing and reuse, and a community wide initiative to overcome them. First, we discuss four bottlenecks to sharing and reuse, present a vision of a future in which these bottlenecks have been ameliorated, and describe the efforts of the initiative's four working groups to address these bottlenecks. We then address the supporting technology and infrastructure that is critical to enabling the vision of the future. Finally, we consider topics of longer-range interest by reviewing some of the research issues raised by our vision.

Epilepsy Genetics—Past, Present, and Future

PubMed Central

Poduri, Annapurna; Lowenstein, Daniel

2014-01-01

Human epilepsy is a common and heterogeneous condition in which genetics play an important etiological role. We begin by reviewing the past history of epilepsy genetics, a field that has traditionally included studies of pedigrees with epilepsy caused by defects in ion channels and neurotransmitters. We highlight important recent discoveries that have expanded the field beyond the realm of channels and neurotransmitters and that have challenged the notion that single genes produce single disorders. Finally, we project toward an exciting future for epilepsy genetics as large-scale collaborative phenotyping studies come face to face with new technologies in genomic medicine. PMID:21277190

ICRF-edge and surface interactions

NASA Astrophysics Data System (ADS)

D'Ippolito, D. A.; Myra, J. R.

2011-08-01

This paper describes a number of deleterious interactions between radio-frequency (rf) waves and the boundary plasma in fusion experiments. These effects can lead to parasitic power dissipation, reduced heating efficiency, formation of hot spots at material boundaries, sputtering and self-sputtering, and arcing in the antenna structure. Minimizing these interactions is important to the success of rf heating, especially in future experiments with long-pulse or steady-state operation, higher power density, and high-Z divertor and walls. These interactions will be discussed with experimental examples. Finally, the present state of modeling and future plans will be summarized.

Current Realities and Future Possibilities: Language and Science Literacy--Empowering Research and Informing Instruction

ERIC Educational Resources Information Center

Yore, Larry D.; Treagust, David F.

2006-01-01

In this final article, we briefly review and synthesize the science and language research and practice that arose from the current literature and presentations at an international conference, referred to as the first "Island Conference". We add to the synthesis of the articles the conference deliberations and on-going discussions of the field and…

Challenges in Leadership in Vocational Education. National EPD Leadership Development Seminar Proceedings (Atlantic City, New Jersey, December 2, 1977). Final Report.

ERIC Educational Resources Information Center

Bottoms, Gene; And Others

Current delivery systems for vocational education and their implications for the future is the topic of presentations included in this report of an EPDA (Educational Professions Development Act) leadership development seminar. Major contents are an evaluation summary, texts of the three major speeches, and outlines of afternoon interaction…

Performance and Challenges of Point of Use Devices for Lead ...

EPA Pesticide Factsheets

this presentation summarizes the performance of POU devices for the removal of lead and some other metals, in Flint, Michigan. The mechanism of POU filters for metal removal is described as being a combination of physical filtration with surface sorption and adherence to embedded functional groups in the carbon block, along with the certification process and how to find certified products from the web listings. Finally, there is a discussion of several alternative approaches for possible improvement of the NSF/ANSI 53 and 42 standards to improve the amount of protection afforded by the devices, in the future. this presentation summarizes the performance of POU devices for the removal of lead and some other metals, in Flint, Michigan. The mechanism of POU filters for metal removal is described as being a combination of physical filtration with surface sorption and adherence to embedded functional groups in the carbon block, along with the certification process and how to find certified products from the web listings. Finally, there is a discussion of several alternative approaches for possible improvement of the NSF/ANSI 53 and 42 standards to improve the amount of protection afforded by the devices, in the future.

Evaluation of installed solar systems at Navy, Army, and Air Force Bases. Final report, October 1984-September 1985

DOE Office of Scientific and Technical Information (OSTI.GOV)

Durlak, E.R.

1986-05-01

This report presents a summary of the results of site-evaluation inspection conducted at Navy, Army, and Air Force base. The solar systems evaluated included space heating, space cooling, and domestic hot water system. The systems range in size from small two-collector systems to large arrays installed on barracks, mess halls, office buildings, etc. These operational results are presented so that future designs will benefit from the lesson learned in this study.

Three-component laser anemometer measurement systems

NASA Technical Reports Server (NTRS)

Goldman, Louis J.

1991-01-01

A brief overview of the different laser anemometer (LA) optical designs available is presented. Then, the LA techniques that can be used to design a three-component measurement system for annular geometries are described. Some of the facility design considerations unique to these LA systems are also addressed. Following this, the facilities and the LA systems that were used to successfully measure the three components of velocity in the blading of annular-flow machines are reviewed. Finally, possible LA system enhancements and future research directions are presented.

Expert systems in transmission planning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Galiana, F.D.; McGillis, D.T.; Marin, M.A.

1992-05-01

In this paper the state of the field of expert systems and knowledge engineering in transmission planning is reviewed. A detailed analysis of the goals, definition, requirements and methodology of transmission planning is presented. Potential benefits of knowledge-based applications in transmission planning are reviewed. This is followed by a thorough review of the area broken down into subareas or important related topics. The conclusions offer a number of suggestions for possible future research and development. Finally, a detailed bibliography divided into subareas is presented.

Modeling Primary Breakup: A Three-Dimensional Eulerian Level Set/Vortex Sheet Method for Two-Phase Interface Dynamics

NASA Technical Reports Server (NTRS)

Herrmann, M.

2003-01-01

This paper is divided into four parts. First, the level set/vortex sheet method for three-dimensional two-phase interface dynamics is presented. Second, the LSS model for the primary breakup of turbulent liquid jets and sheets is outlined and all terms requiring subgrid modeling are identified. Then, preliminary three-dimensional results of the level set/vortex sheet method are presented and discussed. Finally, conclusions are drawn and an outlook to future work is given.

Earth observing system. Output data products and input requirements, version 2.0. Volume 3: Algorithm summary tables and non-EOS data products

NASA Technical Reports Server (NTRS)

Lu, Yun-Chi; Chang, Hyo Duck; Krupp, Brian; Kumar, Ravindar; Swaroop, Anand

1992-01-01

Volume 3 assists Earth Observing System (EOS) investigators in locating required non-EOS data products by identifying their non-EOS input requirements and providing the information on data sets available at various Distributed Active Archive Centers (DAAC's), including those from Pathfinder Activities and Earth Probes. Volume 3 is intended to complement, not to duplicate, the the EOSDIS Science Data Plan (SDP) by providing detailed data set information which was not presented in the SDP. Section 9 of this volume discusses the algorithm summary tables containing information on retrieval algorithms, expected outputs and required input data. Section 10 describes the non-EOS input requirements of instrument teams and IDS investigators. Also described are the current and future data holdings of the original seven DAACS and data products planned from the future missions and projects including Earth Probes and Pathfinder Activities. Section 11 describes source of information used in compiling data set information presented in this volume. A list of data set attributes used to describe various data sets is presented in section 12 along with their descriptions. Finally, Section 13 presents the SPSO's future plan to improve this report .

Positive Technologies for Understanding and Promoting Positive Emotions.

PubMed

Baños, Rosa María; Carrillo, Alba; Etchemendy, Ernestina; Botella, Cristina

2017-10-26

Information and Communication Technologies (ICTs) have become increasingly present in our lives, and their use has spread considerably. This paper presents a review of the way ICTs can help practitioners and researchers to study, promote, and train positive emotions. It is framed within the field of Positive Technologies: the applied scientific approach to the study of the use of technology to improve the quality of personal experience, with the goal of increasing wellbeing. First, the article presents an introduction to the topic of technologies and positive emotions. Then, it describes how ICTs can aid in monitoring, assessing, promoting, modifying, and training positive emotions. Finally, implications and future directions of the role of Positive Technologies in positive emotions are discussed. The authors conclude that, in the near future, Positive Technologies and the field of positive emotions will interact synergistically, producing an exponential growth in the understanding and promotion of positive emotions.

A conceptual solution for a beam halo collimation system for the Future Circular hadron-hadron Collider (FCC-hh)

NASA Astrophysics Data System (ADS)

Fiascaris, M.; Bruce, R.; Redaelli, S.

2018-06-01

We present the first conceptual solution for a collimation system for the hadron-hadron option of the Future Circular Collider (FCC-hh). The collimation layout is based on the scaling of the present Large Hadron Collider collimation system to the FCC-hh energy and it includes betatron and momentum cleaning, as well as dump protection collimators and collimators in the experimental insertions for protection of the final focus triplet magnets. An aperture model for the FCC-hh is defined and the geometrical acceptance is calculated at injection and collision energy taking into account mechanical and optics imperfections. The performance of the system is then assessed through the analysis of normalized halo distributions and complete loss maps for an ideal lattice. The performance limitations are discussed and a solution to improve the system performance with the addition of dispersion suppression collimators around the betatron cleaning insertion is presented.

Natural history, treatment and prevention of hepatitis C recurrence after liver transplantation: past, present and future.

PubMed

Dumortier, Jérôme; Boillot, Olivier; Scoazec, Jean-Yves

2014-08-28

Hepatitis C virus (HCV)-related liver disease, including cirrhosis and hepatocellular carcinoma is the main indication for liver transplantation (LT) worldwide. Post-transplant HCV re-infection is almost universal and results in accelerated progression from acute hepatitis to chronic hepatitis, and liver cirrhosis. Comprehension and treatment of recurrent HCV infection after LT have been major issues for all transplant hepatologists and transplant surgeons for the last decades. The aim of this paper is to review the evolution of our knowledge on the natural history of HCV recurrence after LT, including risk factors for disease progression, and antiviral therapy. We will focus our attention on possible ways (present and future) to improve the final long-term results of LT for HCV-related liver disease.

Speckle interferometry with PISCO in Merate and prospects for the future

NASA Astrophysics Data System (ADS)

Scardia, M.; Prieur, J. L.; Argyle, R. W.; Pansecchi, L.; Gili, R.; Koechlin, L.

2012-05-01

Speckle interferometry measurements of binary stars have been regularly obtained with PISCO at the 1-meter Zeiss telescope of the I.N.A.F. - Osservatorio Astronomico di Brera (Merate, Italy) since the end of 2003. We present here some recent results and some projects for extending and improving the scientific reach of our program. In particular, we plan to acquire more efficient detectors and install PISCO on a computer-controlled telescope in a better site belonging to Observatoire de la Côte d'Azur (OCA, Caussols, France). In the future, we would like to be able to operate remotely PISCO, its detector and the telescope. Finally we present PISCO2, the new speckle camera of our group that has been built for the OCA 76-cm refractor.)

Software architecture and engineering for patient records: current and future.

PubMed

Weng, Chunhua; Levine, Betty A; Mun, Seong K

2009-05-01

During the "The National Forum on the Future of the Defense Health Information System," a track focusing on "Systems Architecture and Software Engineering" included eight presenters. These presenters identified three key areas of interest in this field, which include the need for open enterprise architecture and a federated database design, net centrality based on service-oriented architecture, and the need for focus on software usability and reusability. The eight panelists provided recommendations related to the suitability of service-oriented architecture and the enabling technologies of grid computing and Web 2.0 for building health services research centers and federated data warehouses to facilitate large-scale collaborative health care and research. Finally, they discussed the need to leverage industry best practices for software engineering to facilitate rapid software development, testing, and deployment.

A 6-DOF parallel bone-grinding robot for cervical disc replacement surgery.

PubMed

Tian, Heqiang; Wang, Chenchen; Dang, Xiaoqing; Sun, Lining

2017-12-01

Artificial cervical disc replacement surgery has become an effective and main treatment method for cervical disease, which has become a more common and serious problem for people with sedentary work. To improve cervical disc replacement surgery significantly, a 6-DOF parallel bone-grinding robot is developed for cervical bone-grinding by image navigation and surgical plan. The bone-grinding robot including mechanical design and low level control is designed. The bone-grinding robot navigation is realized by optical positioning with spatial registration coordinate system defined. And a parametric robot bone-grinding plan and high level control have been developed for plane grinding for cervical top endplate and tail endplate grinding by a cylindrical grinding drill and spherical grinding for two articular surfaces of bones by a ball grinding drill. Finally, the surgical flow for a robot-assisted cervical disc replacement surgery procedure is present. The final experiments results verified the key technologies and performance of the robot-assisted surgery system concept excellently, which points out a promising clinical application with higher operability. Finally, study innovations, study limitations, and future works of this present study are discussed, and conclusions of this paper are also summarized further. This bone-grinding robot is still in the initial stage, and there are many problems to be solved from a clinical point of view. Moreover, the technique is promising and can give a good support for surgeons in future clinical work.

Communication satellite payload technologies - State of the art and trends in Europe

NASA Astrophysics Data System (ADS)

Mica, G.; Coirault, R.

1982-09-01

Communication satellite payload technologies are examined, in terms of past, present, and future ESA guidelines. Various existing payload systems are presented, such as Marecs, ECS, and L-Sat (which will carry four payloads). Future services within the market include 2 Mb/sec high speed data, 2-8 Mb/sec video conference, and 64 Mb/sec television distribution, and growth in these areas is dependent on traffic requirements. Pre-operational satellites are outlined, for example Telecom 1 has an estimated system capacity of 150 Mb/sec, Italsat has an expected 1180 Mb/sec, and DFS demonstrates a possible 1540 Mb/sec capacity. It is found that the 20/30 GHz band should be applied for use in wideband and high capacity trunks among heavy traffic centers. To accommodate for the noise in this waveband, the parametric amplifier developed for L-Sat must be used. Finally, development objectives for future programs include improving spectrum and geostationary orbit utilization, cost-efficiency, and standardization of systems.

Artificial intelligence and synthetic biology: A tri-temporal contribution.

PubMed

Bianchini, Francesco

2016-10-01

Artificial intelligence can make numerous contributions to synthetic biology. I would like to suggest three that are related to the past, present and future of artificial intelligence. From the past, works in biology and artificial systems by Turing and von Neumann prove highly interesting to explore within the new framework of synthetic biology, especially with regard to the notions of self-modification and self-replication and their links to emergence and the bottom-up approach. The current epistemological inquiry into emergence and research on swarm intelligence, superorganisms and biologically inspired cognitive architecture may lead to new achievements on the possibilities of synthetic biology in explaining cognitive processes. Finally, the present-day discussion on the future of artificial intelligence and the rise of superintelligence may point to some research trends for the future of synthetic biology and help to better define the boundary of notions such as "life", "cognition", "artificial" and "natural", as well as their interconnections in theoretical synthetic biology. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Insights from a Recent Meeting: Current Status and Future Directions in Magnesium Corrosion Research

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brady, Michael P.; Joost, William J.; David Warren, C.

The United States Department of Energy Vehicle Technologies Office held a Technical Review Meeting entitled “Current Status and Future Directions in Magnesium Corrosion Research” at Oak Ridge National Laboratory in April 2016. Here current funded Mg corrosion projects presented their latest results, along with invited presentations from academic and industrial researchers in the area of Mg corrosion. This paper overviews select topics from the meeting, with an emphasis on relaying meeting discussion points regarding future needs in understanding and mitigating Mg corrosion, particularly for automotive applications. Topics highlighted include the need for pretreatments and coatings suitable for mass vehicle productionmore » of Mg components, particularly for dissimilar metal joints involving Mg, Al, or steel, and corrosion evaluation methods more relevant to automotive components and operating conditions. Finally, from a scientific perspective, the need for better fundamental understanding of Mg dissolution, hydrogen evolution, and film formation behavior was a recurring theme, as was phenomena related to microgalvanic coupling involving second phases and impurities in Mg.« less

Insights from a Recent Meeting: Current Status and Future Directions in Magnesium Corrosion Research

DOE PAGES

Brady, Michael P.; Joost, William J.; David Warren, C.

2016-11-17

The United States Department of Energy Vehicle Technologies Office held a Technical Review Meeting entitled “Current Status and Future Directions in Magnesium Corrosion Research” at Oak Ridge National Laboratory in April 2016. Here current funded Mg corrosion projects presented their latest results, along with invited presentations from academic and industrial researchers in the area of Mg corrosion. This paper overviews select topics from the meeting, with an emphasis on relaying meeting discussion points regarding future needs in understanding and mitigating Mg corrosion, particularly for automotive applications. Topics highlighted include the need for pretreatments and coatings suitable for mass vehicle productionmore » of Mg components, particularly for dissimilar metal joints involving Mg, Al, or steel, and corrosion evaluation methods more relevant to automotive components and operating conditions. Finally, from a scientific perspective, the need for better fundamental understanding of Mg dissolution, hydrogen evolution, and film formation behavior was a recurring theme, as was phenomena related to microgalvanic coupling involving second phases and impurities in Mg.« less

[Older female employees in Germany - structures of employment and perspectives of the future].

PubMed

Clemens, W

2006-02-01

This contribution presents an overview to the structures and conditions of employment of older female employees in Germany. Based on information about the labor force participation rates, rates of unemployment and occupational patterns the conditions of female employment beyond midlife are examined. Relating to the standard of living, the meaning of employment for older women is discussed. Furthermore, the effects of regulations of welfare state, i. e., pension systems, on future life of the employed women are highlighted. Further topics are the completion of working life and the transition to retirement of female employees, the issue of the future working conditions of older female employees related with demographic change und future reduction of the potential of labor force. Finally the contribution stresses the importance of a holistic approach to investigate the living and working conditions of older female employees.

A robotic exploration mission to Mars and Phobos

NASA Technical Reports Server (NTRS)

Kerr, Justin H.; Defosse, Erin; Ho, Quang; Barriga, Ernisto; Davis, Grant; Mccourt, Steve; Smith, Matt

1993-01-01

This report discusses the design of a robotic exploration to Mars and Phobos. It begins with the mission's background and objectives, followed by a detailed explanation of various elements of Project Aeneas, including science, spacecraft, probes, and orbital trajectories. In addition, a description of Argos Space Endeavours, management procedures, and overall project costs are presented. Finally, a list of recommendations for future design activity is included.

A Dying Child in the Family: The Child's and Sibling's Perspective. Selected Papers, Number 60.

ERIC Educational Resources Information Center

Said, John

Children and adolescents have different understandings of death. For the baby, death is equated with separation. For toddlers, grief occurs when they realize the person is not returning. The preschool child who tends to live in the present with no clear concept of past or future will not understand the finality. Around ages 4 and 5, death is often…

LORAN-C LATITUDE-LONGITUDE CONVERSION AT SEA: PROGRAMMING CONSIDERATIONS.

USGS Publications Warehouse

McCullough, James R.; Irwin, Barry J.; Bowles, Robert M.

1985-01-01

Comparisons are made of the precision of arc-length routines as computer precision is reduced. Overland propagation delays are discussed and illustrated with observations from offshore New England. Present practice of LORAN-C error budget modeling is then reviewed with the suggestion that additional terms be considered in future modeling. Finally, some detailed numeric examples are provided to help with new computer program checkout.

Modular Engine Noise Component Prediction System (MCP) Technical Description and Assessment Document

NASA Technical Reports Server (NTRS)

Herkes, William H.; Reed, David H.

2005-01-01

This report describes an empirical prediction procedure for turbofan engine noise. The procedure generates predicted noise levels for several noise components, including inlet- and aft-radiated fan noise, and jet-mixing noise. This report discusses the noise source mechanisms, the development of the prediction procedures, and the assessment of the accuracy of these predictions. Finally, some recommendations for future work are presented.

Multi-Core Processors: An Enabling Technology for Embedded Distributed Model-Based Control (Postprint)

DTIC Science & Technology

2008-07-01

generation of process partitioning, a thread pipelining becomes possible. In this paper we briefly summarize the requirements and trends for FADEC based... FADEC environment, presenting a hypothetical realization of an example application. Finally we discuss the application of Time-Triggered...based control applications of the future. 15. SUBJECT TERMS Gas turbine, FADEC , Multi-core processing technology, disturbed based control

From Innovative Programs to Systemic Education Reform: Lesson from Five Communities. The Final Report of the Benchmark Communities Initiative.

ERIC Educational Resources Information Center

DeSalvatore, Larry; Goldberger, Susan; Steinberg, Adria

This document presents the lessons of Jobs for the Future's Benchmark Communities Initiative (BCI), a 5-year systemic educational reform initiative launched in 1994 in five communities. Before joining the BCI, the five Benchmark communities had each begun a school-to-career effort. Five key findings from the BCI are outlined: (1) students engaged…

A Two-Tiered-Testing Decision Tree for Assays in the USEPA-EDSP Screening Battery: Using 15 years of experience to improve screening and testing for endocrine active chemicals

EPA Science Inventory

Outline of the presentationEDCs – from 1991 to 1996 – Wingspread and Our Stolen Future 1996 – FQPA and SDWA mandates endocrine screening 1996-1998 – EDSTAC (the assays, debates over modes of action included) The final battery – EAT in vivo and in vit...

Development of a high resolution stepper motor prototype. volume 1: general presentation. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1975-12-01

This motor could be used to drive large solar panels of future satellites. Its main performance characteristics are as follows: 1,200 steps per revolution, relaxation torque greater than 0.3 mN, holding torque greater than 1mN, and input power at full torque less than 1.5 W. For volume 2 and 3; see ESR-97067. (GRA)

Introduction to the special issue on the personality assessment inventory.

PubMed

Kurtz, John E; Blais, Mark A

2007-02-01

This special issue of the Journal of Personality Assessment brings together 13 new research studies on the Personality Assessment Inventory (PAI; Morey, 1991) that should inform users and stimulate future empirical activity with this measure. In 4 articles, authors evaluate the validity scales and indexes of the PAI using both analog and criterion designs and samples from a variety of clinical and forensic settings. In a 5th article, the authors describe a novel approach to profile interpretation using two PAI negative distortion measures. The authors present applications of the PAI to new populations and problems including a German translation of the PAI and profile information for male batterers and victims of head injury. The authors of 2 studies extend research on the validity of the PAI for the assessment of borderline personality disorder. In the final 3 studies, the authors evaluate the validity of PAI measures of violence and aggression to predict subsequent aggressive behavior and institutional misconduct. Finally, the authors offer several suggestions for future research with the PAI.

AeroPropulsoServoElasticity: Dynamic Modeling of the Variable Cycle Propulsion System

NASA Technical Reports Server (NTRS)

Kopasakis, George

2012-01-01

This presentation was made at the 2012 Fundamental Aeronautics Program Technical Conference and it covers research work for the Dynamic Modeling of the Variable cycle Propulsion System that was done under the Supersonics Project, in the area of AeroPropulsoServoElasticity. The presentation covers the objective for the propulsion system dynamic modeling work, followed by the work that has been done so far to model the variable Cycle Engine, modeling of the inlet, the nozzle, the modeling that has been done to model the affects of flow distortion, and finally presenting some concluding remarks and future plans.

SP-100 Program: space reactor system and subsystem investigations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harty, R.B.

1983-09-30

For a space reactor power system, a comprehensive safety program will be required to assure that no undue risk is present. This report summarizes the nuclear safety review/approval process that will be required for a space reactor system. The documentation requirements are presented along with a summary of the required contents of key documents. Finally, the aerospace safety program conducted for the SNAP-10A reactor system is summarized. The results of this program are presented to show the type of program that can be expected and to provide information that could be usable in future programs.

SP-100 program: Space reactor system and subsystem investigations

NASA Astrophysics Data System (ADS)

Harty, R. B.

1983-09-01

For a space reactor power system, a comprehensive safety program will be required to assure that no undue risk is present. The nuclear safety review/approval process that is required for a space reactor system is summarized. The documentation requirements are presented along with a summary of the required contents of key documents. Finally, the aerospace safety program conducted for the SNAP-10A reactor system is summarized. The results of this program are presented to show the type of program that is expected and to provide information that could be usable in future programs.

Forecasting the Future Food Service World of Work. Final Report. Volume III. Technical Papers on the Future of the Food Service Industry. Service Management Reports.

ERIC Educational Resources Information Center

Powers, Thomas F., Ed.; Swinton, John R., Ed.

This third and final volume of a study on the future of the food service industry contains the technical papers on which the information in the previous two volumes was based. The papers were written by various members of the Pennsylvania State University departments of economics, food science, nutrition, social psychology, and engineering and by…

New control strategies with inertial monolithic sensors: advantages and limitations in the control of benches and platforms for seismic isolation

NASA Astrophysics Data System (ADS)

Barone, F.; Giordano, G.; Acernese, F.; Romano, R.

2018-03-01

In this paper, we present some innovative and general strategies for the control of benches and platforms, that the introduction of the new class of monolithic UNISA Folded Pendulum is now making it possible, also in terms of environmental conditions, like ultra-high-vacuum (UHV), cryogenics and harsh environments. In particular, we present and discuss a parametric analysis of the control models in connection with the sensors limitations in terms of sensitivity and band. Finally, we present and discuss some experimental laboratory tests on a laboratory platform, underlining the present advantages and the expected future improvements.

Spin physics through unpolarized processes

NASA Astrophysics Data System (ADS)

Lu, Zhun

2016-02-01

This article presents a review of our present understanding of the spin structure of the unpolarized hadron. Particular attention is paid to the quark sector at leading twist, namely, the quark Boer-Mulders function, which describes the transverse polarization of the quark inside an unpolarized hadron. After introducing the operator definition of the Boer-Mulders function, a detailed treatment of different non-perturbative calculations of the Boer-Mulders functions is provided. The phenomenology in Drell-Yan processes and semi-inclusive leptoproduction, including the extraction of the quark and antiquark Boer-Mulders functions from experimental data, is presented comprehensively. Finally, prospects for future theoretical studies and experimental measurements are presented in brief.

Integrated Modeling and Decision-Support System for Water Management in the Puget Sound Basin: Snow Caps to White Caps

DOE Office of Scientific and Technical Information (OSTI.GOV)

Copping, Andrea E.; Yang, Zhaoqing; Voisin, Nathalie

2013-12-01

Final Report for the EPA-sponsored project Snow Caps to White Caps that provides data products and insight for water resource managers to support their predictions and management actions to address future changes in water resources (fresh and marine) in the Puget Sound basin. This report details the efforts of a team of scientists and engineers from Pacific Northwest National Laboratory (PNNL) and the University of Washington (UW) to examine the movement of water in the Snohomish Basin, within the watershed and the estuary, under present and future conditions, using a set of linked numerical models.

Getting Ready for the "School of the Future": Key Questions and Tentative Answers

NASA Astrophysics Data System (ADS)

Ott, Michela; Pozzi, Francesca

This paper explores some key aspects of "today's school", as opposed to those that have characterized "yesterday's school", with the final aim of shedding light on "tomorrow's school". In this direction, the paper puts forward tentative answers to some key questions related to the new characteristics and roles of teachers and students (main actors of the learning process) and the new features/ potentialities of contemporary educational tools which, in turn, require the enactment of innovative pedagogical approaches and educational methods. The emerging picture of the present learning landscape helps in figuring out a future situation where learning possibilities are substantially increased.

Space transfer vehicle concepts and requirements study. Volume 2, book 3: STV system interfaces

NASA Technical Reports Server (NTRS)

Weber, Gary A.

1991-01-01

This report presents the results of systems analyses and conceptual design of space transfer vehicles (STV). The missions examined included piloted and unpiloted lunar outpost support and spacecraft servicing, and unpiloted payload delivery to various earth and solar orbits. The study goal was to examine the mission requirements and provide a decision data base for future programmatic development plans. The final lunar transfer vehicles provided a wide range of capabilities and interface requirements while maintaining a constant payload mission model. Launch vehicle and space station sensitivity was examined, with the final vehicles as point design covering the range of possible options. Development programs were defined and technology readiness levels for different options were determined. Volume 1 presents the executive summary, volume 2 provides the study results, and volume 3 the cost and WBS data.

Effect of temperature shock and inventory surprises on natural gas and heating oil futures returns.

PubMed

Hu, John Wei-Shan; Hu, Yi-Chung; Lin, Chien-Yu

2014-01-01

The aim of this paper is to examine the impact of temperature shock on both near-month and far-month natural gas and heating oil futures returns by extending the weather and storage models of the previous study. Several notable findings from the empirical studies are presented. First, the expected temperature shock significantly and positively affects both the near-month and far-month natural gas and heating oil futures returns. Next, significant temperature shock has effect on both the conditional mean and volatility of natural gas and heating oil prices. The results indicate that expected inventory surprises significantly and negatively affects the far-month natural gas futures returns. Moreover, volatility of natural gas futures returns is higher on Thursdays and that of near-month heating oil futures returns is higher on Wednesdays than other days. Finally, it is found that storage announcement for natural gas significantly affects near-month and far-month natural gas futures returns. Furthermore, both natural gas and heating oil futures returns are affected more by the weighted average temperature reported by multiple weather reporting stations than that reported by a single weather reporting station.

Effect of Temperature Shock and Inventory Surprises on Natural Gas and Heating Oil Futures Returns

PubMed Central

Hu, John Wei-Shan; Lin, Chien-Yu

2014-01-01

The aim of this paper is to examine the impact of temperature shock on both near-month and far-month natural gas and heating oil futures returns by extending the weather and storage models of the previous study. Several notable findings from the empirical studies are presented. First, the expected temperature shock significantly and positively affects both the near-month and far-month natural gas and heating oil futures returns. Next, significant temperature shock has effect on both the conditional mean and volatility of natural gas and heating oil prices. The results indicate that expected inventory surprises significantly and negatively affects the far-month natural gas futures returns. Moreover, volatility of natural gas futures returns is higher on Thursdays and that of near-month heating oil futures returns is higher on Wednesdays than other days. Finally, it is found that storage announcement for natural gas significantly affects near-month and far-month natural gas futures returns. Furthermore, both natural gas and heating oil futures returns are affected more by the weighted average temperature reported by multiple weather reporting stations than that reported by a single weather reporting station. PMID:25133233

Goldilocks and the Three Planets

NASA Astrophysics Data System (ADS)

Fillingim, M. O.; Brain, D. A.; Peticolas, L. M.; Yan, D.; Fricke, K.

2010-12-01

Just after their formation, the atmospheres of Venus, Earth, and Mars are though to have been very similar. Why are they so different today? We are developing a series of presentations that investigates the differences in the atmospheres of Venus, Earth, and Mars, and how these differences arose. These presentations are a combination of planetary images displayed on engaging spherical displays and visual demonstrations. We recently tested and evaluated our first presentation on the Lawrence Hall of Science's six-foot diameter Science on a Sphere. We will briefly summarize this presentation and the evaluation results. The target audience for this initial presentation is elementary school age children. Future presentations will target middle school and high school age students focusing on planetary magnetic fields and the role they play in atmospheric evolution. Our future plans include transferring these presentations onto a portable, table top spherical display system to take into classrooms. Finally, we are also building rigid, three-dimensional wire models of the magnetic fields and Venus, Earth, and Mars for use in the traveling presentations. We will tie the development and debut of these presentations to appropriate topics throughout the Year of the Solar System.

Value and Payment in Sleep Medicine.

PubMed

Wickwire, Emerson M; Verma, Tilak

2018-05-15

Value, like beauty, exists in the eye of the beholder. This article places the value of clinical sleep medicine services in historical context and presents a vision for the value-based sleep of the future. First, the history of value and payment in sleep medicine is reviewed from the early days of the field, to innovative disruption, to the widespread adoption of home sleep apnea testing. Next, the importance of economic perspective is discussed, with emphasis on cost containment and cost-shifting between payers, employers, providers, and patients. Specific recommendations are made for sleep medicine providers and the field at large to maximize the perceived value of sleep. Finally, alternate payment models and value-based care are presented, with an eye toward the future for clinical service providers as well as integrated health delivery networks. © 2018 American Academy of Sleep Medicine.

Shuttle get-away special experiments

NASA Technical Reports Server (NTRS)

Orton, George

1987-01-01

This presentation describes two shuttle Get-Away-Special (GAS) experiments built by McDonnell Douglas to investigate low-g propellant acquisition and gaging. The first experiment was flown on shuttle mission 41-G in October 1984. The second experiment has been qualified for flight and is waiting for a flight assignment. The tests performed to qualify these experiments for flight are described, and the lessons learned which can be applied to future GAS experiments are discussed. Finally, survey results from 134 GAS experiments flown to date are presented. On the basis of these results it is recommended that future GAS experiments be qualified to shuttle thermal and dynamic environments through a rigorous series of mission operating tests. Furthermore, should automatic activation of the experiment be required during the boost phase of the mission, NASA-supplied redundant barometric switches should be employed to trigger the activation.

The design of PC/MISI, a PC-based common user interface to remote information storage and retrieval systems. Presentation visuals. M.S. Thesis Final Report, 1 Jul. 1985 - 31 Dec. 1987

NASA Technical Reports Server (NTRS)

Dominick, Wayne D. (Editor); Hall, Philip P.

1985-01-01

This Working Paper Series entry represents a collection of presentation visuals associated with the companion report entitled, The Design of PC/MISI, a PC-Based Common User Interface to Remote Information Storage and Retrieval Systems, USL/DBMS NASA/RECON Working Paper Series report number DBMS.NASA/RECON-15. The paper discusses the following: problem definition; the PC solution; the goals of system design; the design description; future considerations, the research environment; conclusions.

Data compression for full motion video transmission

NASA Technical Reports Server (NTRS)

Whyte, Wayne A., Jr.; Sayood, Khalid

1991-01-01

Clearly transmission of visual information will be a major, if not dominant, factor in determining the requirements for, and assessing the performance of the Space Exploration Initiative (SEI) communications systems. Projected image/video requirements which are currently anticipated for SEI mission scenarios are presented. Based on this information and projected link performance figures, the image/video data compression requirements which would allow link closure are identified. Finally several approaches which could satisfy some of the compression requirements are presented and possible future approaches which show promise for more substantial compression performance improvement are discussed.

DISCOS- Current Status and Future Developments

NASA Astrophysics Data System (ADS)

Flohrer, T.; Lemmens, S.; Bastida Virgili, B.; Krag, H.; Klinkrad, H.; Parrilla, E.; Sanchez, N.; Oliveira, J.; Pina, F.

2013-08-01

We present ESA's Database and Information System Characterizing Objects in Space (DISCOS). DISCOS not only plays an essential role in the collision avoidance and re-entry prediction services provided by ESA's Space Debris Office, it is also providing input to numerous and very differently scoped engineering activities, within ESA and throughout industry. We introduce the central functionalities of DISCOS, present the available reporting capabilities, and describe selected data modelling features. Finally, we revisit the developments of the recent years and take a sneak preview of the on-going replacement of DISCOS web front-end.

High resolution observations using adaptive optics: Achievements and future needs

NASA Astrophysics Data System (ADS)

Sankarasubramanian, K.; Rimmele, T.

2008-06-01

Over the last few years, several interesting observations were obtained with the help of solar Adaptive Optics (AO). In this paper, few observations made using the solar AO are enlightened and briefly discussed. A list of disadvantages with the current AO system are presented. With telescopes larger than 1.5 m expected during the next decade, there is a need to develop the existing AO technologies for large aperture telescopes. Some aspects of this development are highlighted. Finally, the recent AO developments in India are also presented.

Opportunities for increasing natural gas production in the near term. Volume VI. The East Cameron Block 271 Field. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1978-02-01

This report examines the potential for increasing the rate of production of natural gas from the East Cameron Block 271 Field in the Gulf of Mexico Outer Continental Shelf. Proved reserves are estimated using all available reservoir data, including well logs and pressure tests, and cost parameters typical in the area. Alternative schedules for future production are devised, and net present values calculated from which the maximum production rate that also maximizes net present value is determined.

Galileo Press Conference from JPL. Parts 1 and 2

NASA Technical Reports Server (NTRS)

1992-01-01

This two-tape Jet Propulsion Laboratory (JPL) video production presents a Dec. 8, 1992 press conference held at JPL to discuss the final Galileo spacecraft encounter with Earth before beginning its journey to Jupiter. The main theme of the conference was centered on the significance of the 2nd and final Earth/Moon flyby as being the spacecraft's last planetary encounter in the solar system before reaching Jupiter, as well as final flight preparations prior to its final journey. Each person of the five member panel was introduced by Robert MacMillan (JPL Public Information Mgr.) before giving brief presentations including slides and viewgraphs covering their area of expertise regarding Galileo's current status and future plans. After the presentations, the media was given an opportunity to ask questions of the panel regarding the mission. Mr. Wesley Huntress (Dir. of Solar System Exploration (NASA)), William J. ONeill (Galileo Project Manager), Neal E. Ausman, Jr. (Galileo Mission Director), Dr. Torrence V. Johnson (Galileo Project Scientist) and Dr. Ronald Greeley (Member, Imaging Team, Colorado St. Univ.) made up the panel and discussed topics including: Galileo's interplanetary trajectory; project status and performance review; instrument calibration activities; mission timelines; lunar observation and imaging; and general lunar science. Also included in the last three minutes of the video are simulations and images of the 2nd Galileo/Moon encounter.

Review of electrotechnologies used in the disinfection of water and wastewater. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

VandeVenter, L.W.

This report provides an overview of the disinfection practices used in water and wastewater treatment. Chlorine historically has been the disinfectant of choice for both water and wastewater, but with increased research and more stringent regulations, other disinfectants, namely ozone and ultraviolet irradiation, are being considered. The report summarizes the present and future applications of these technologies and defines possible opportunities for Demand- Side Management (DSM).

International Conference in Computational Cell Biology: From the Past to the Future

DTIC Science & Technology

2016-09-12

24061 -0001 ABSTRACT Number of Papers published in peer -reviewed journals: Number of Papers published in non peer -reviewed journals: Final Report...present their latest research and discussed challenges in computational cell biology research and education. (a) Papers published in peer -reviewed...List the papers, including journal references, in the following categories: (b) Papers published in non- peer -reviewed journals (N/A for none) (c

A historical overview of flight flutter testing

NASA Technical Reports Server (NTRS)

Kehoe, Michael W.

1995-01-01

This paper reviews the test techniques developed over the last several decades for flight flutter testing of aircraft. Structural excitation systems, instrumentation systems, digital data preprocessing, and parameter identification algorithms (for frequency and damping estimates from the response data) are described. Practical experiences and example test programs illustrate the combined, integrated effectiveness of the various approaches used. Finally, comments regarding the direction of future developments and needs are presented.

Analysis of the Death Gratuity Program: History, Current Issues and Future Implications

DTIC Science & Technology

2005-12-01

addition to the death gratuity, there are also a number of other benefits available to families and beneficiaries upon the death of a servicemember...An entire chapter is dedicated to covering these other benefits . Finally, this project analyzes an alternative method of funding the death gratuity...program and presents the advantages and drawbacks of such an alternative. 15. NUMBER OF PAGES 59 14. SUBJECT TERMS Death gratuity

A perspective on unstructured grid flow solvers

NASA Technical Reports Server (NTRS)

Venkatakrishnan, V.

1995-01-01

This survey paper assesses the status of compressible Euler and Navier-Stokes solvers on unstructured grids. Different spatial and temporal discretization options for steady and unsteady flows are discussed. The integration of these components into an overall framework to solve practical problems is addressed. Issues such as grid adaptation, higher order methods, hybrid discretizations and parallel computing are briefly discussed. Finally, some outstanding issues and future research directions are presented.

Unfurlable satellite antennas - A review

NASA Technical Reports Server (NTRS)

Roederer, Antoine G.; Rahmat-Samii, Yahia

1989-01-01

A review of unfurlable satellite antennas is presented. Typical application requirements for future space missions are first outlined. Then, U.S. and European mesh and inflatable antenna concepts are described. Precision deployables using rigid panels or petals are not included in the survey. RF modeling and performance analysis of gored or faceted mesh reflector antennas are then reviewed. Finally, both on-ground and in-orbit RF test techniques for large unfurlable antennas are discussed.

Intended location of future career practice among graduating medical students: perspective from social cognitive career theory in Nepal.

PubMed

Sapkota, B P; Amatya, A

2013-09-01

Medical workforce shortages and mal-distributions world-wide make understanding how, where and what our future doctors wish to practice is increasingly important. Understanding of factors such as available infrastructure, provision of incentives and many others influences the decisions of doctors to leave or to stay. Therefore the strategies effective for retention, is imperative in conducting the study based on a sound theoretical framework in predicting future medical workforce needs. The study used the theoretical framework of Social Cognitive Career Theory to identify the predictors on future practice location. The study was cross-sectional descriptive in design targeting the Nepalese medical students in the final year and doing internships in Nepal. Anonymous self administered questionnaire was distributed among 480 students but 393 students were involved due to non response and incompleteness. Findings of the study were presented in frequency tables for univariate descriptive analysis and bivariate findings were presented by cross tabulation. About two thirds 259 (65.9%) of the participants had chosen within country location for future practice. Among those who had chosen within country choice, about an equal percentage of the respondents had chosen rural 131 (50.8%) and urban 128 (49.2%) location. Among those who had chosen within country for future practice location, less than one fifth of the participants had chosen private sector for future practice. Majority of the medical graduates wish to practice within country location. Most of which chose public sector for future practice. None of the SCCT construct had any significant association within country location.

Buildings of the Future Scoping Study: A Framework for Vision Development

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Na; Goins, John D.

2015-02-01

The Buildings of the Future Scoping Study, funded by the U.S. Department of Energy (DOE) Building Technologies Office, seeks to develop a vision for what U.S. mainstream commercial and residential buildings could become in 100 years. This effort is not intended to predict the future or develop a specific building design solution. Rather, it will explore future building attributes and offer possible pathways of future development. Whether we achieve a more sustainable built environment depends not just on technologies themselves, but on how effectively we envision the future and integrate these technologies in a balanced way that generates economic, social,more » and environmental value. A clear, compelling vision of future buildings will attract the right strategies, inspire innovation, and motivate action. This project will create a cross-disciplinary forum of thought leaders to share their views. The collective views will be integrated into a future building vision and published in September 2015. This report presents a research framework for the vision development effort based on a literature survey and gap analysis. This document has four objectives. First, it defines the project scope. Next, it identifies gaps in the existing visions and goals for buildings and discusses the possible reasons why some visions did not work out as hoped. Third, it proposes a framework to address those gaps in the vision development. Finally, it presents a plan for a series of panel discussions and interviews to explore a vision that mitigates problems with past building paradigms while addressing key areas that will affect buildings going forward.« less

Final Progress Report for Collaborative Research: Aging of Black Carbon during Atmospheric Transport: Understanding Results from the DOE’s 2010 CARES and 2012 ClearfLo Campaigns

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mazzoleni, Claudio; Subramanian, R.

2016-08-31

Over the course of this project, we have analyzed data and samples from the Carbonaceous Aerosol and Radiative Effects Study (CARES) and the Clear air for London (ClearfLo) campaign, as well as conducted or participated in laboratory experiments designed to better understand black carbon mixing state and climate-relevant properties. The laboratory campaigns took place at the Pacific Northwest National Laboratory and Carnegie Mellon University to study various climate-relevant aerosol properties of different sources of soot mixing with secondary organic aerosol precursors. Results from some of these activities were summarized in the previous progress report. This final report presents the manuscriptsmore » that have been published (many in the period since the last progress report), lists presentations at different conferences based on grant-related activities, and presents some results that are likely to be submitted for publication in the near future.« less

GRoW Buffalo Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bohm, Martha

This document provides final reporting on the GRoW Home, University at Buffalo's entry to the 2015 Solar Decathlon competition in Irvine, CA. The report summarizes fundraising efforts, documents media outreach, lists online presence, analyzes the organizer's communication, describes post-competition life of the house and future employment plans for student team members. Last, it suggests improvements for future decathlons.

Analysis of Human Body Bipedal Stability for Neuromotor Disabilities

NASA Astrophysics Data System (ADS)

Baritz, Mihaela; Cristea, Luciana; Rogozea, Liliana; Cotoros, Diana; Repanovici, Angela

2009-04-01

The analysis of different biomechanical aspects of balance and equilibrium is presented in the first part of the paper. We analyzed the posture, balance and stability of human body for a normal person and for a person with loco-motor or neuro-motor disabilities (in the second part). In the third part of the paper we presented the methodology and the experimental setup used to record the human body behavior in postural stability for persons with neuro-motors disabilities. The results and the conclusions are presented in the final part of the paper and also in the future work meant to establish the computer analysis for rehabilitation neuromotor disabilities.

Hierarchical Traces for Reduced NSM Memory Requirements

NASA Astrophysics Data System (ADS)

Dahl, Torbjørn S.

This paper presents work on using hierarchical long term memory to reduce the memory requirements of nearest sequence memory (NSM) learning, a previously published, instance-based reinforcement learning algorithm. A hierarchical memory representation reduces the memory requirements by allowing traces to share common sub-sequences. We present moderated mechanisms for estimating discounted future rewards and for dealing with hidden state using hierarchical memory. We also present an experimental analysis of how the sub-sequence length affects the memory compression achieved and show that the reduced memory requirements do not effect the speed of learning. Finally, we analyse and discuss the persistence of the sub-sequences independent of specific trace instances.

Active controls: A look at analytical methods and associated tools

NASA Technical Reports Server (NTRS)

Newsom, J. R.; Adams, W. M., Jr.; Mukhopadhyay, V.; Tiffany, S. H.; Abel, I.

1984-01-01

A review of analytical methods and associated tools for active controls analysis and design problems is presented. Approaches employed to develop mathematical models suitable for control system analysis and/or design are discussed. Significant efforts have been expended to develop tools to generate the models from the standpoint of control system designers' needs and develop the tools necessary to analyze and design active control systems. Representative examples of these tools are discussed. Examples where results from the methods and tools have been compared with experimental data are also presented. Finally, a perspective on future trends in analysis and design methods is presented.

The Misfortunes of Moral Enhancement.

PubMed

Azevedo, Marco Antonio

2016-10-01

In Unfit for the Future, Ingmar Persson and Julian Savulescu present a sophisticated argument in defense of the imperative of moral enhancement. They claim that without moral enhancement, the future of humanity is seriously compromised. The possibility of ultimate harm, caused by a dreadful terrorist attack or by a final unpreventable escalation of the present environmental crisis aggravated by the availability of cognitive enhancement, makes moral enhancement a top priority. It may be considered optimistic to think that our present moral capabilities can be successfully improved by means of moral education, moral persuasion, and fear of punishment. So, without moral enhancement, drastic restrictions on human freedom would become the only alternative to prevent those dramatic potential outcomes. In this article, I will try to show that we still have reason to be less pessimistic and that Persson & Savulescu's arguments are fortunately unconvincing. © The Author 2016. Published by Oxford University Press, on behalf of the Journal of Medicine and Philosophy Inc. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Systems biology for molecular life sciences and its impact in biomedicine.

PubMed

Medina, Miguel Ángel

2013-03-01

Modern systems biology is already contributing to a radical transformation of molecular life sciences and biomedicine, and it is expected to have a real impact in the clinical setting in the next years. In this review, the emergence of systems biology is contextualized with a historic overview, and its present state is depicted. The present and expected future contribution of systems biology to the development of molecular medicine is underscored. Concerning the present situation, this review includes a reflection on the "inflation" of biological data and the urgent need for tools and procedures to make hidden information emerge. Descriptions of the impact of networks and models and the available resources and tools for applying them in systems biology approaches to molecular medicine are provided as well. The actual current impact of systems biology in molecular medicine is illustrated, reviewing two cases, namely, those of systems pharmacology and cancer systems biology. Finally, some of the expected contributions of systems biology to the immediate future of molecular medicine are commented.

Phased-array-fed antenna configuration study, volume 2

NASA Technical Reports Server (NTRS)

Sorbello, R. M.; Zaghloul, A. I.; Lee, B. S.; Siddiqi, S.; Geller, B. D.

1983-01-01

Increased capacity in future satellite systems can be achieved through antenna systems which provide multiplicity of frequency reuses at K sub a band. A number of antenna configurations which can provide multiple fixed spot beams and multiple independent spot scanning beams at 20 GHz are addressed. Each design incorporates a phased array with distributed MMIC amplifiers and phasesifters feeding a two reflector optical system. The tradeoffs required for the design of these systems and the corresponding performances are presented. Five final designs are studied. In so doing, a type of MMIC/waveguide transition is described, and measured results of the breadboard model are presented. Other hardware components developed are described. This includes a square orthomode transducer, a subarray fed with a beamforming network to measure scanning performance, and another subarray used to study mutual coupling considerations. Discussions of the advantages and disadvantages of the final design are included.

Measurement in Service Businesses: Challenges and Future Directions

NASA Astrophysics Data System (ADS)

Tyagi, Rajesh Kumar

This chapter presents challenges faced by service businesses while implementing a measurement system. A review of existing frameworks is presented and a new framework, the Service Scorecard, is introduced. The Service Scorecard is an adaptation of the Six Sigma Business Scorecard for the service sector. The framework has also been influenced by existing frameworks such as the Malcom Baldrige award criteria, the Balanced Scorecard, the European Quality award and the Service Profit Chain model. The seven elements of the Service Scorecard are Growth, Leadership, Acceleration, Collaboration, Innovation, Execution, and Retention. The examples of measurement systems are presented with concrete real-world case examples. Final thoughts and the challenges faced are also presented.

Relativity of Simultaneity and Eternalism: In Defense of the Block Universe

NASA Astrophysics Data System (ADS)

Peterson, Daniel; Silberstein, Michael

Ever since Hermann Minkowski's now infamous comments in 1908 concerning the proper way to view space-time, the debate has raged as to whether or not the universe should be viewed as a four-dimensional, unified whole wherein the past, present, and future are regarded as equally real or whether the views espoused by the possibilists, historicists, and presentists regarding the unreality of the future (and, for presentists, the past) are more accurate. Now, a century after Minkowski's proposed block universe first sparked debate, we present a new, more conclusive argument in favor of the eternalism. Utilizing an argument based on the relativity of simultaneity in the tradition of Putnam and Rietdijk and explicit novel but reasonable assumptions as to the nature of reality, we argue that the past, present, and future should be treated as equally real, thus ruling that presentism and other theories of time that bestow special ontological status to the past, present, or future are untenable. Finally, we respond to our critics who suggest that: (1) there is no metaphysical difference between the positions of eternalism and presentism, (2) the present must be defined as the "here" as well as the "now", or (3) presentism is correct and physicists' current understanding of relativity is incomplete because it does not incorporate a preferred frame. We call response 1 deflationary since it purports to dissolve or deconstruct the age-old debate between the two views and response 2 compatibilist because it does nothing to alter special relativity (SR), arguing instead that SR unadorned has the resources to save presentism. Response 3 we will call incompatibilist because it adorns SR in some way in order to save presentism a la some sort of preferred frame. We show that neither 1 nor 2 can save presentism and 3 is not well motivated at this juncture except as an ad hoc device to refute eternalism.

Innovative hazard detection and avoidance strategy for autonomous safe planetary landing

NASA Astrophysics Data System (ADS)

Jiang, Xiuqiang; Li, Shuang; Tao, Ting

2016-09-01

Autonomous hazard detection and avoidance (AHDA) is one of the key technologies for future safe planetary landing missions. In this paper, we address the latest progress on planetary autonomous hazard detection and avoidance technologies. First, the innovative autonomous relay hazard detection and avoidance strategy adopted in Chang'e-3 lunar soft landing mission and its flight results are reported in detail. Second, two new conceptual candidate schemes of hazard detection and avoidance are presented based on the Chang'e-3 AHDA system and the latest developing technologies for the future planetary missions, and some preliminary testing results are also given. Finally, the related supporting technologies for the two candidate schemes above are analyzed.

Introduction to "Global Tsunami Science: Past and Future, Volume I"

NASA Astrophysics Data System (ADS)

Geist, Eric L.; Fritz, Hermann M.; Rabinovich, Alexander B.; Tanioka, Yuichiro

2016-12-01

Twenty-five papers on the study of tsunamis are included in Volume I of the PAGEOPH topical issue "Global Tsunami Science: Past and Future". Six papers examine various aspects of tsunami probability and uncertainty analysis related to hazard assessment. Three papers relate to deterministic hazard and risk assessment. Five more papers present new methods for tsunami warning and detection. Six papers describe new methods for modeling tsunami hydrodynamics. Two papers investigate tsunamis generated by non-seismic sources: landslides and meteorological disturbances. The final three papers describe important case studies of recent and historical events. Collectively, this volume highlights contemporary trends in global tsunami research, both fundamental and applied toward hazard assessment and mitigation.

Embodied Space: a Sensorial Approach to Spatial Experience

NASA Astrophysics Data System (ADS)

Durão, Maria João

2009-03-01

A reflection is presented on the significance of the role of the body in the interpretation and future creation of spatial living structures. The paper draws on the body as cartography of sensorial meaning that includes vision, touch, smell, hearing, orientation and movement to discuss possible relationships with psychological and sociological parameters of 'sensorial space'. The complex dynamics of body-space is further explored from the standpoint of perceptual variables such as color, light, materialities, texture and their connections with design, technology, culture and symbology. Finally, the paper discusses the integration of knowledge and experimentation in the design of future habitats where body-sensitive frameworks encompass flexibility, communication, interaction and cognitive-driven solutions.

Hot Water Propulsion for Horizontal Rocket Assisted Take-Off Systems for Future Reusable Launch Vehicles

NASA Astrophysics Data System (ADS)

Pilz, N.; Adirim, H.; Lo, R.; Schildknecht, A.

2004-10-01

Among other concepts, reusable space transportation systems that comprise winged reusable launch vehicles (RLV) with horizontal take-off and horizontal landing (HTHL) are under worldwide investigation, e.g. the respective concepts within ESA's FESTIP-Study (Future European Space Transportation Integration Program) or the HOPPER concept by EADS-ST. The payload of these RLVs could be significantly increased by means of a ground-based take-off assistance system that would accelerate the vehicle along a horizontal track until it reaches the desired speed to ignite its onboard engines for leaving the ground and launching into orbit. This paper illustrates the advantages of horizontal take-off for winged RLVs and provides an overview of launch-assist options for HTHL RLVs. It presents hot water propulsion for ground-based take-off assistance systems for future RLVs as an attractive choice besides magnetic levitation and acceleration (maglev) technology. Finally, preliminary design concepts are presented for a rocket assisted take-off system (RATOS) with hot water propulsion followed by an analysis of its improvement potential.

Staffing the ISS Control Centers: Lessons Learned from Long-Duration Human Space Flight

NASA Technical Reports Server (NTRS)

Olsen, Carrie D.; Horvath, Timothy J.; Davis, Sally P.

2006-01-01

The International Space Station (ISS) has been in operation with a permanent human presence in space for over five years, and plans for continued operations stretch ten years into the future. Ground control and support operations are, likewise, a 15-year enterprise. This long-term, 24-hour per day, 7 day per week support has presented numerous challenges in the areas of ground crew training, initial and continued certification, and console staffing. The Mission Control Center in Houston, Texas and the Payload Operations Center in Huntsville, Alabama have both tackled these challenges, with similar, yet distinct, approaches. This paper describes the evolution of the staffing and training policies of both control centers in a chronological progression. The relative merits and shortcomings of the various policies employed are discussed and a summary of "lessons learned" is presented. Finally, recommendations are made as best practices for future long-term space missions.

Metal hydride hydrogen compression: recent advances and future prospects

NASA Astrophysics Data System (ADS)

Yartys, Volodymyr A.; Lototskyy, Mykhaylo; Linkov, Vladimir; Grant, David; Stuart, Alastair; Eriksen, Jon; Denys, Roman; Bowman, Robert C.

2016-04-01

Metal hydride (MH) thermal sorption compression is one of the more important applications of the MHs. The present paper reviews recent advances in the field based on the analysis of the fundamental principles of this technology. The performances when boosting hydrogen pressure, along with two- and three-step compression units, are analyzed. The paper includes also a theoretical modelling of a two-stage compressor aimed at describing the performance of the experimentally studied systems, their optimization and design of more advanced MH compressors. Business developments in the field are reviewed for the Norwegian company HYSTORSYS AS and the South African Institute for Advanced Materials Chemistry. Finally, future prospects are outlined presenting the role of the MH compression in the overall development of the hydrogen-driven energy systems. The work is based on the analysis of the development of the technology in Europe, USA and South Africa.

Public health assessment for Bloomington PCB sites, Bloomington, Monroe County, Indiana and Spencer, Owen County, Indiana. Region 5. Volumes 1, 2, and 3. Revised November 15, 1996. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The Public Health Assessment for Bloomington PCB Sites (PHA) is the Agency for Toxic Substances and Disease Registry`s (ATSDR) evaluation of the public health impact of six sites in and around Bloomington, Indiana, and the public health considerations for technologies that could be used to remediate the sites. Volume I contains an evaluation of past, present, and future health implications based on available environmental and health outcome data and pathways of potential human exposure. Volume II summarizes a number of public health considerations that those selecting remedial options for both incineration and non-incineration remedial technologies for PCB wastes must evaluate.more » Volume III provides the bases for the overall conclusions and recommendations the agency reached regarding public health hazards associated with the Bloomington PCB sites under past, present, and future conditions.« less

Metal hydride hydrogen compression: Recent advances and future prospects

DOE PAGES

Bowman, Jr., Robert C.; Yartys, Volodymyr A.; Lototskyy, Mykhaylo V.; ...

2016-03-17

Metal hydride (MH) thermal sorption compression is one of the more important applications of the metal hydrides. The present paper reviews recent advances in the field based on the analysis of the fundamental principles of this technology. The performances when boosting hydrogen pressure, along with two- and three-step compression units are analyzed. The paper includes also a theoretical modeling of a two-stage compressor aimed at both describing the performance of the experimentally studied systems, but, also, on their optimization and design of more advanced MH compressors. Business developments in the field are reviewed for the Norwegian company HYSTORSYS AS andmore » the South African Institute for Advanced Materials Chemistry. Finally, future prospects are outlined presenting the role of the metal hydride compression in the overall development of the hydrogen driven energy systems. Lastly, the work is based on the analysis of the development of the technology in Europe, USA and South Africa.« less

Quo vadis, analytical chemistry?

PubMed

Valcárcel, Miguel

2016-01-01

This paper presents an open, personal, fresh approach to the future of Analytical Chemistry in the context of the deep changes Science and Technology are anticipated to experience. Its main aim is to challenge young analytical chemists because the future of our scientific discipline is in their hands. A description of not completely accurate overall conceptions of our discipline, both past and present, to be avoided is followed by a flexible, integral definition of Analytical Chemistry and its cornerstones (viz., aims and objectives, quality trade-offs, the third basic analytical reference, the information hierarchy, social responsibility, independent research, transfer of knowledge and technology, interfaces to other scientific-technical disciplines, and well-oriented education). Obsolete paradigms, and more accurate general and specific that can be expected to provide the framework for our discipline in the coming years are described. Finally, the three possible responses of analytical chemists to the proposed changes in our discipline are discussed.

Clinical linguistics: its past, present and future.

PubMed

Perkins, Michael R

2011-11-01

Historiography is a growing area of research within the discipline of linguistics, but so far the subfield of clinical linguistics has received virtually no systematic attention. This article attempts to rectify this by tracing the development of the discipline from its pre-scientific days up to the present time. As part of this, I include the results of a survey of articles published in Clinical Linguistics & Phonetics between 1987 and 2008 which shows, for example, a consistent primary focus on phonetics and phonology at the expense of grammar, semantics and pragmatics. I also trace the gradual broadening of the discipline from its roots in structural linguistics to its current reciprocal relationship with speech and language pathology and a range of other academic disciplines. Finally, I consider the scope of clinical linguistic research in 2011 and assess how the discipline seems likely develop in the future.

International terrorism and mental health: recent research and future directions.

PubMed

Fischer, Peter; Ai, Amy L

2008-03-01

International terrorism has become a major global concern. Several studies conducted in North America and Europe in the aftermath of terrorist attacks reveal that international terrorism represents a significant short-term and long-term threat to mental health. In the present article, the authors clarify the concept and categories of terrorism and then present central findings from studies conducted in the United States and Europe, which mainly focus on negative impacts on mental health, such as emotional stress and PTSD. Furthermore, the authors outline experiments that focus on social interaction processes thought to be triggered by international terrorism and which are assumed to be related indirectly to mental health processes. Next, they highlight the potential positive outcomes on the resilience side, in line with the current theory on posttraumatic growth in adversity. Finally, theoretical and practical implications as well as limitations and future directions are discussed.

Study on the water related disaster risks using the future socio-economic scenario in Asia

NASA Astrophysics Data System (ADS)

Kiguchi, M.; Hatono, M.; Ikeuchi, H.; Nakamura, S.; Hirabayashi, Y.; Kanae, S.; Oki, T.

2014-12-01

In this study, flood risks in the present and the end of the 21st century in Asia are estimated using a future socio-economic scenario. Using the runoff data of 7 GCMs (RCP 8.5) of CMIP5, the river discharge, inundation area, and inundation depth are calculated for the assessment of flood risk. Finally, the flood risk is estimated using a function of damage. The flood frequency in the end of the 21st century in Asia tends to increase. Inundation area in Japan, Taiwan, and Kyrgyz is almost unchanged. At the same time, that in Sri Lanka, Bangladesh, Laos, and Myanmar reached about 1.4-1.6 times compared to present. Damage cost is largely influenced by economic growth, however, we show that it is important that we distinguish the influence of climate change from economic development and evaluate it when we think about an adaptation.

Lithium-ion conducting electrolyte salts for lithium batteries.

PubMed

Aravindan, Vanchiappan; Gnanaraj, Joe; Madhavi, Srinivasan; Liu, Hua-Kun

2011-12-16

This paper presents an overview of the various types of lithium salts used to conduct Li(+) ions in electrolyte solutions for lithium rechargeable batteries. More emphasis is paid towards lithium salts and their ionic conductivity in conventional solutions, solid-electrolyte interface (SEI) formation towards carbonaceous anodes and the effect of anions on the aluminium current collector. The physicochemical and functional parameters relevant to electrochemical properties, that is, electrochemical stabilities, are also presented. The new types of lithium salts, such as the bis(oxalato)borate (LiBOB), oxalyldifluoroborate (LiODFB) and fluoroalkylphosphate (LiFAP), are described in detail with their appropriate synthesis procedures, possible decomposition mechanism for SEI formation and prospect of using them in future generation lithium-ion batteries. Finally, the state-of-the-art of the system is given and some interesting strategies for the future developments are illustrated. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Report of the In Situ Resources Utilization Workshop

NASA Technical Reports Server (NTRS)

Fairchild, Kyle (Editor); Mendell, Wendell W. (Editor)

1988-01-01

The results of a workshop of 50 representatives from the public and private sector which investigated the potential joint development of the key technologies and mechanisms that will enable the permanent habitation of space are presented. The workshop is an initial step to develop a joint public/private assessment of new technology requirements of future space options, to share knowledge on required technologies that may exist in the private sector, and to investigate potential joint technology development opportunities. The majority of the material was produced in 5 working groups: (1) Construction, Assembly, Automation and Robotics; (2) Prospecting, Mining, and Surface Transportation; (3) Biosystems and Life Support; (4) Materials Processing; and (5) Innovative Ventures. In addition to the results of the working groups, preliminary technology development recommendations to assist in near-term development priority decisions are presented. Finally, steps are outlined for potential new future activities and relationships among the public, private, and academic sectors.

African swine fever virus: current state and future perspectives in vaccine and antiviral research.

PubMed

Zakaryan, Hovakim; Revilla, Yolanda

2016-03-15

African swine fever (ASF) is among the most significant of swine diseases for which no effective vaccines and antivirals are available. The disease, which is endemic in Africa, was introduced to Trans-Caucasian countries and the Russian Federation in 2007, where it remains prevalent today among domestic pigs and wild boars. Although some measures were implemented, ASF continues to pose a global risk for all countries, and thereby highlighting the importance of vaccine and antiviral research. In this review, an overview of research efforts toward the development of effective vaccines during the past decades is presented. As an alternative to vaccine development, the current state in antiviral research against ASFV is also presented. Finally, future perspectives in vaccine and antiviral research giving emphasis on some strategies that may allow researchers to develop effective countermeasures against ASF are discussed. Copyright © 2016 Elsevier B.V. All rights reserved.

3D Human Motion Editing and Synthesis: A Survey

PubMed Central

Wang, Xin; Chen, Qiudi; Wang, Wanliang

2014-01-01

The ways to compute the kinematics and dynamic quantities of human bodies in motion have been studied in many biomedical papers. This paper presents a comprehensive survey of 3D human motion editing and synthesis techniques. Firstly, four types of methods for 3D human motion synthesis are introduced and compared. Secondly, motion capture data representation, motion editing, and motion synthesis are reviewed successively. Finally, future research directions are suggested. PMID:25045395

The State of the Art and Practice in Digital Preservation

PubMed Central

Lee, Kyong-Ho; Slattery, Oliver; Lu, Richang; Tang, Xiao; McCrary, Victor

2002-01-01

The goal of digital preservation is to ensure long-term access to digitally stored information. In this paper, we present a survey of techniques used in digital preservation. We also introduce representative digital preservation projects and case studies that provide insight into the advantages and disadvantages of different preservation strategies. Finally, the pros and cons of current strategies, critical issues for digital preservation, and future directions are discussed. PMID:27446721

Microgravity research at the University of Mexico: Experiments in payload G-006

NASA Technical Reports Server (NTRS)

Peralta-Fabi, Ricardo; Mendieta-Jimenez, Javier

1988-01-01

The experiments contained in the G-006 payload related to thin film vapor deposition, vacuum variations in a chamber vented to space, solidification of a Zn-Al-Cu alloy, and multiple location temperature monitoring for thermal model validation are described in detail. A discussion of the expected results is presented, together with the methods selected to conduct the postflight analysis, and finally, a overview of the future activities in this field.

High efficiency IR supercontinuum generation and applications: a review

NASA Astrophysics Data System (ADS)

Yin, Shizhuo; Ruffin, Paul; Brantley, Christina; Edwards, Eugene; Cheng, Jiping; Yao, Jimmy; Luo, Claire

2011-10-01

In this paper, we have reviewed our recent works on IR supercontinuum generation (SCG) and its applications. First, we provide a brief review on the physical mechanism of the supercontinuum generation and our previous works in this field. Second, the transmission characteristics of a new type of IR fibers is presented. Furthermore, the SCG generation in this new type of optical fiber is experimentally demonstrated. Finally, the suggestion for the future effort is discussed.

Computerizing Audit Studies

PubMed Central

Lahey, Joanna N.; Beasley, Ryan A.

2014-01-01

This paper briefly discusses the history, benefits, and shortcomings of traditional audit field experiments to study market discrimination. Specifically it identifies template bias and experimenter bias as major concerns in the traditional audit method, and demonstrates through an empirical example that computerization of a resume or correspondence audit can efficiently increase sample size and greatly mitigate these concerns. Finally, it presents a useful meta-tool that future researchers can use to create their own resume audits. PMID:24904189

Current and anticipated uses of thermal-hydraulic codes in NFI

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tsuda, K.; Takayasu, M.

1997-07-01

This paper presents the thermal-hydraulic codes currently used in NFI for the LWR fuel development and licensing application including transient and design basis accident analyses of LWR plants. The current status of the codes are described in the context of code capability, modeling feature, and experience of code application related to the fuel development and licensing. Finally, the anticipated use of the future thermal-hydraulic code in NFI is briefly given.

Environmental compatibility of closed landfills - assessing future pollution hazards.

PubMed

Laner, David; Fellner, Johann; Brunner, Paul H

2011-01-01

Municipal solid waste landfills need to be managed after closure. This so-called aftercare comprises the treatment and monitoring of residual emissions as well as the maintenance and control of landfill elements. The measures can be terminated when a landfill does not pose a threat to the environment any more. Consequently, the evaluation of landfill environmental compatibility includes an estimation of future pollution hazards as well as an assessment of the vulnerability of the affected environment. An approach to assess future emission rates is presented and discussed in view of long-term environmental compatibility. The suggested method consists (a) of a continuous model to predict emissions under the assumption of constant landfill conditions, and (b) different scenarios to evaluate the effects of changing conditions within and around the landfill. The model takes into account the actual status of the landfill, hence different methods to gain information about landfill characteristics have to be applied. Finally, assumptions, uncertainties, and limitations of the methodology are discussed, and the need for future research is outlined.

Informatics and Nursing in a Post-Nursing Informatics World: Future Directions for Nurses in an Automated, Artificially Intelligent, Social-Networked Healthcare Environment.

PubMed

Booth, Richard G

2016-01-01

The increased adoption and use of technology within healthcare and society has influenced the nursing informatics specialty in a multitude of fashions. Namely, the nursing informatics specialty currently faces a range of important decisions related to its knowledge base, established values and future directions - all of which are in need of development and future-proofing. In light of the increased use of automation, artificial intelligence and big data in healthcare, the specialty must also reconceptualize the roles of both nurses and informaticians to ensure that the nursing profession is ready to operate within future digitalized healthcare ecosystems. To explore these goals, the author of this manuscript outlines an examination of technological advancements currently taking place within healthcare, and also proposes implications for the nursing role and the nursing informatics specialty. Finally, recommendations and insights towards how the roles of nurses and informaticians might evolve or be shaped in the growing post-nursing informatics era are presented. Copyright © 2016 Longwoods Publishing.

Recent developments in the structural design and optimization of ITER neutral beam manifold

NASA Astrophysics Data System (ADS)

Chengzhi, CAO; Yudong, PAN; Zhiwei, XIA; Bo, LI; Tao, JIANG; Wei, LI

2018-02-01

This paper describes a new design of the neutral beam manifold based on a more optimized support system. A proposed alternative scheme has presented to replace the former complex manifold supports and internal pipe supports in the final design phase. Both the structural reliability and feasibility were confirmed with detailed analyses. Comparative analyses between two typical types of manifold support scheme were performed. All relevant results of mechanical analyses for typical operation scenarios and fault conditions are presented. Future optimization activities are described, which will give useful information for a refined setting of components in the next phase.

Soft Tissue Closure of Grafted Extraction Sockets in the Anterior Maxilla: A Modified Palatal Pedicle Connective Tissue Flap Technique.

PubMed

El Chaar, Edgard; Oshman, Sarah; Cicero, Giuseppe; Castano, Alejandro; Dinoi, Cinzia; Soltani, Leila; Lee, Yoonjung Nicole

Localized ridge resorption, the consequence of socket collapse, following tooth extraction in the anterior maxilla can adversely affect esthetics, function, and future implant placement. Immediate grafting of extraction sockets may help preserve natural ridge contours, but a lack of available soft tissue can compromise the final esthetic outcome. The presented modified rotated palatal pedicle connective tissue flap is a useful technique for simultaneous soft tissue coverage and augmentation of grafted sockets to improve esthetic outcome. This article delineates its advantages through the presentation of a four-case series using this new technique.

Optical spectroscopy of laser-produced plasmas for standoff isotopic analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harilal, Sivanandan S.; Brumfield, Brian E.; LaHaye, Nicole L.

2018-04-20

This review article covers the present status of isotope detection through emission, absorption, and fluorescence spectroscopy of atoms and molecules in a laser-produced plasma formed from a solid sample. A description of the physics behind isotope shifts in atoms and molecules is presented, followed by the physics behind solid sampling of laser ablation plumes, optical methods for isotope measurements, the suitable physical conditions of laser-produced plasma plumes for isotopic analysis, and the current status. Finally, concluding remarks will be made on the existing gaps between previous works in the literature and suggestions for future work.

SEEDS Moving Group Status Update

NASA Technical Reports Server (NTRS)

McElwain, Michael

2011-01-01

I will summarize the current status of the SEEDS Moving Group category and describe the importance of this sub-sample for the entire SEEDS survey. This presentation will include analysis of the sensitivity for the Moving Groups with general a comparison to other the other sub-categories. I will discuss the future impact of the Subaru SCExAO system for these targets and the advantage of using a specialized integral field spectrograph. Finally, I will present the impact of a pupil grid mask in order to produce fiducial spots in the focal plane that can be used for both photometry and astrometry.

Optical spectroscopy of laser-produced plasmas for standoff isotopic analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harilal, S. S.; Brumfield, B. E.; LaHaye, N. L.

This review article covers the present status of isotope detection through emission, absorption, and fluorescence spectroscopy of atoms and molecules in a laser-produced plasma formed from a solid sample. A description of the physics behind isotope shifts in atoms and molecules is presented, followed by the physics behind solid sampling of laser ablation plumes, optical methods for isotope measurements, the suitable physical conditions of laser-produced plasma plumes for isotopic analysis, and the current status. Finally, concluding remarks will be made on the existing gaps between previous works in the literature and suggestions for future work.

[Research progress on real-time deformable models of soft tissues for surgery simulation].

PubMed

Xu, Shaoping; Liu, Xiaoping; Zhang, Hua; Luo, Jie

2010-04-01

Biological tissues generally exhibit nonlinearity, anisotropy, quasi-incompressibility and viscoelasticity about material properties. Simulating the behaviour of elastic objects in real time is one of the current objectives of virtual surgery simulation which is still a challenge for researchers to accurately depict the behaviour of human tissues. In this paper, we present a classification of the different deformable models that have been developed. We present the advantages and disadvantages of each one. Finally, we make a comparison of deformable models and perform an evaluation of the state of the art and the future of deformable models.

Methamphetamine-induced toxicity: an updated review on issues related to hyperthermia

PubMed Central

Matsumoto, Rae R.; Seminerio, Michael J.; Turner, Ryan C.; Robson, Matthew J.; Nguyen, Linda; Miller, Diane B.; O’Callaghan, James P.

2015-01-01

Reports of methamphetamine-related emergency room visits suggest that elevated body temperature is a universal presenting symptom, with lethal overdoses generally associated with extreme hyperthermia. This review summarizes the available information on methamphetamine toxicity as it pertains to elevations in body temperature. First, a brief overview of thermoregulatory mechanisms is presented. Next, central and peripheral targets that have been considered for potential involvement in methamphetamine hyperthermia are discussed. Finally, future areas of investigation are proposed, as further studies are needed to provide greater insight into the mechanisms that mediate the alterations in body temperature elicited by methamphetamine. PMID:24836729

Optical spectroscopy of laser-produced plasmas for standoff isotopic analysis

DOE PAGES

Harilal, S. S.; Brumfield, B. E.; LaHaye, N. L.; ...

2018-06-01

This review article covers the present status of isotope detection through emission, absorption, and fluorescence spectroscopy of atoms and molecules in a laser-produced plasma formed from a solid sample. A description of the physics behind isotope shifts in atoms and molecules is presented, followed by the physics behind solid sampling of laser ablation plumes, optical methods for isotope measurements, the suitable physical conditions of laser-produced plasma plumes for isotopic analysis, and the current status. Finally, concluding remarks will be made on the existing gaps between previous works in the literature and suggestions for future work.

Updated Review of Planetary Atmospheric Electricity

NASA Astrophysics Data System (ADS)

Yair, Y.; Fischer, G.; Simões, F.; Renno, N.; Zarka, P.

2008-06-01

This paper reviews the progress achieved in planetary atmospheric electricity, with focus on lightning observations by present operational spacecraft, aiming to fill the hiatus from the latest review published by Desch et al. (Rep. Prog. Phys. 65:955 997, 2002). The information is organized according to solid surface bodies (Earth, Venus, Mars and Titan) and gaseous planets (Jupiter, Saturn, Uranus and Neptune), and each section presents the latest results from space-based and ground-based observations as well as laboratory experiments. Finally, we review planned future space missions to Earth and other planets that will address some of the existing gaps in our knowledge.

Updated Review of Planetary Atmospheric Electricity

NASA Astrophysics Data System (ADS)

Yair, Y.; Fischer, G.; Simões, F.; Renno, N.; Zarka, P.

This paper reviews the progress achieved in planetary atmospheric electricity, with focus on lightning observations by present operational spacecraft, aiming to fill the hiatus from the latest review published by Desch et al. (Rep. Prog. Phys. 65:955-997, 2002). The information is organized according to solid surface bodies (Earth, Venus, Mars and Titan) and gaseous planets (Jupiter, Saturn, Uranus and Neptune), and each section presents the latest results from space-based and ground-based observations as well as laboratory experiments. Finally, we review planned future space missions to Earth and other planets that will address some of the existing gaps in our knowledge.

Integration of Mobile Health Technology in the Treatment of Chronic Pain: A Critical Review.

PubMed

Sundararaman, Lalitha V; Edwards, Robert R; Ross, Edgar L; Jamison, Robert N

This article provides a critical overview and best-evidence synthesis of the use of mobile health (mHealth) technology among persons with chronic pain and their health care providers and examines the future benefits and barriers of implementing mHealth technology in clinical care. We critically review articles about electronic pain diaries, pain assessment programs, text messaging, and smartphone pain apps for management of persons with pain. Also presented are findings on the utility of activity trackers and use of telehealth to deliver cognitive behavioral therapy. Finally, barriers, study gaps, and future challenges of incorporating mobile technology for chronic pain are discussed. Although the future of mHealth technology and telemedicine in clinical practice is promising, this critical review highlights the need for rigorous studies to establish an association of the use of mHealth technology with improved quality of life, functional autonomy, and decreased hospital use.

Mapping remote and multidisciplinary learning barriers: lessons from challenge-based innovation at CERN

NASA Astrophysics Data System (ADS)

Jensen, Matilde Bisballe; Utriainen, Tuuli Maria; Steinert, Martin

2018-01-01

This paper presents the experienced difficulties of students participating in the multidisciplinary, remote collaborating engineering design course challenge-based innovation at CERN. This is with the aim to identify learning barriers and improve future learning experiences. We statistically analyse the rated differences between distinct design activities, educational background and remote vs. co-located collaboration. The analysis is based on a quantitative and qualitative questionnaire (N = 37). Our analysis found significant ranking differences between remote and co-located activities. This questions whether the remote factor might be a barrier for the originally intended learning goals. Further a correlation between analytical and converging design phases was identified. Hence, future facilitators are suggested to help students in the transition from one design phase to the next rather than only teaching methods in the individual design phases. Finally, we discuss how educators address the identified learning barriers when designing future courses including multidisciplinary or remote collaboration.

Impacts of Present and Future Climate Variability on Forest Ecosystem in Mediterranean Region

NASA Astrophysics Data System (ADS)

Ozcan, O.; Musaoglu, N.; Türkeş, M.

2017-12-01

The concept of `climate change vulnerability' helps us to better comprehend the cause/effect relationships behind climate change and its impact on human societies, socioeconomic sectors, physiographical and ecological systems. Herein, multifactorial spatial modeling was applied to evaluate the vulnerability of a Mediterranean forest ecosystem to climate change. Thus, the geographical distribution of the final Environmental Vulnerability Areas (EVAs) of the forest ecosystem are based on the estimated final Environmental Vulnerability Index (EVI) values. This revealed that at current levels of environmental degradation, physical, geographical, policy enforcement and socioeconomic conditions, the area with a "very low" vulnerability degree covered mainly the town, its surrounding settlements and the agricultural lands found mainly over the low and flat travertine plateau and the plains at the east and southeast of the district. The spatial magnitude of the EVAs over the forest ecosystem under the current environmental degradation was also determined. This revealed that the EVAs classed as "very low" account for 21% of the total area of the forest ecosystem, those classed as "low" account for 36%, those classed as "medium" account for 20%, and those classed as "high" account for 24%. Based on regionally averaged future climate assessments and projected future climate indicators, both the study site and the western Mediterranean sub-region of Turkey will probably become associated with a drier, hotter, more continental and more water-deficient climate. This analysis holds true for all future scenarios, with the exception of RCP4.5 for the period from 2015 to 2030. However, the present dry-sub humid climate dominating this sub-region and the study area shows a potential for change towards more dry climatology and for it to become a semiarid climate in the period between 2031 and 2050 according to the RCP8.5 high emission scenario. All the observed and estimated results show clearly that the densest forest ecosystem in the southern part of the study site, which is characterized by mainly Mediterranean coniferous and some mixed forest and the maquis vegetation, will very likely be influenced by medium and high degrees of vulnerability to future environmental degradation, climate change and variability.

C-Band Airport Surface Communications System Standards Development. Phase II Final Report. Volume 2: Test Bed Performance Evaluation and Final AeroMACS Recommendations

NASA Technical Reports Server (NTRS)

Hall, Edward; Magner, James

2011-01-01

This report is provided as part of ITT s NASA Glenn Research Center Aerospace Communication Systems Technical Support (ACSTS) contract NNC05CA85C, Task 7: New ATM Requirements-Future Communications, C-Band and L-Band Communications Standard Development and was based on direction provided by FAA project-level agreements for New ATM Requirements-Future Communications. Task 7 included two subtasks. Subtask 7-1 addressed C-band (5091- to 5150-MHz) airport surface data communications standards development, systems engineering, test bed and prototype development, and tests and demonstrations to establish operational capability for the Aeronautical Mobile Airport Communications System (AeroMACS). Subtask 7-2 focused on systems engineering and development support of the L-band digital aeronautical communications system (L-DACS). Subtask 7-1 consisted of two phases. Phase I included development of AeroMACS concepts of use, requirements, architecture, and initial high-level safety risk assessment. Phase II builds on Phase I results and is presented in two volumes. Volume I is devoted to concepts of use, system requirements, and architecture, including AeroMACS design considerations. Volume II (this document) describes an AeroMACS prototype evaluation and presents final AeroMACS recommendations. This report also describes airport categorization and channelization methodologies. The purposes of the airport categorization task were (1) to facilitate initial AeroMACS architecture designs and enable budgetary projections by creating a set of airport categories based on common airport characteristics and design objectives, and (2) to offer high-level guidance to potential AeroMACS technology and policy development sponsors and service providers. A channelization plan methodology was developed because a common global methodology is needed to assure seamless interoperability among diverse AeroMACS services potentially supplied by multiple service providers.

Stakeholder Analysis of an Executable Achitecture Systems Engineering (EASE) Tool

DTIC Science & Technology

2013-06-21

The FCR tables and stakeholder feedback are then used as the foundation of a Strengths, Weaknesses, Opportunities, and Threats ( SWOT ) analysis . Finally...the SWOT analysis and stakeholder feedback arc translated into an EASE future development strategy; a series of recommendations regarding...and Threats ( SWOT ) analysis . Finally, the SWOT analysis and stakeholder feedback are translated into an EASE future development strategy; a series

A State-of-the-Art Review on Soil Reinforcement Technology Using Natural Plant Fiber Materials: Past Findings, Present Trends and Future Directions.

PubMed

Gowthaman, Sivakumar; Nakashima, Kazunori; Kawasaki, Satoru

2018-04-04

Incorporating sustainable materials into geotechnical applications increases day by day due to the consideration of impacts on healthy geo-environment and future generations. The environmental issues associated with conventional synthetic materials such as cement, plastic-composites, steel and ashes necessitate alternative approaches in geotechnical engineering. Recently, natural fiber materials in place of synthetic material have gained momentum as an emulating soil-reinforcement technique in sustainable geotechnics. However, the natural fibers are innately different from such synthetic material whereas behavior of fiber-reinforced soil is influenced not only by physical-mechanical properties but also by biochemical properties. In the present review, the applicability of natural plant fibers as oriented distributed fiber-reinforced soil (ODFS) and randomly distributed fiber-reinforced soil (RDFS) are extensively discussed and emphasized the inspiration of RDFS based on the emerging trend. Review also attempts to explore the importance of biochemical composition of natural-fibers on the performance in subsoil reinforced conditions. The treatment methods which enhances the behavior and lifetime of fibers, are also presented. While outlining the current potential of fiber reinforcement technology, some key research gaps have been highlighted at their importance. Finally, the review briefly documents the future direction of the fiber reinforcement technology by associating bio-mediated technological line.

Persuasive Technology to Support Active and Healthy Ageing: an exploration of Past, Present, and Future.

PubMed

Cabrita, Miriam; Op den Akker, Harm; Tabak, Monique; Hermens, Hermie J; Vollenbroek-Hutten, Miriam M R

2018-06-20

The age of the population worldwide is rapidly increasing, bringing social and economic challenges. Persuasive technology can alleviate the burden on traditional healthcare services when used to support healthy behaviors, for instance in the prevention and treatment of chronic diseases. Additionally, healthy behaviors are key factors for active and healthy ageing by delaying or even reversing functional decline. In this manuscript, we present a multi-perspective analysis of technologies that can be used in the support of active and healthy ageing in the daily life. First, we take the perspective of physical and mental health, by focusing on the promotion of physical activity and emotional wellbeing. From a temporal perspective, we look at how technology evolved from past, present and future. The overview of the literature is structured in four main sections: (1) measurement of current behavior (monitoring), (2) analysis of the data gathered to derive meaningful information (analyzing & reasoning), (3) support the individual in the adoption or maintenance of a behavior (coaching), and (4) tools or interfaces that provide the information to the individual to stimulate the desired behavior (applications). Finally, we provide recommendations for the design, development and implementation of future technological innovations to support Active and Healthy Ageing in daily life. Copyright © 2018. Published by Elsevier Inc.

30,000 years of hydroclimatic variability in the coastal southwest United States: regional synthesis and forcings analysis.

NASA Astrophysics Data System (ADS)

Kirby, M. E.

2015-12-01

The coastal southwest United States is characterized by a winter dominated hydroclimate. Far from dependable, this region's supply of winter precipitation is highly variable and often characterized by hydrologic opposites - droughts and floods. Predicting future precipitation and hydrologic dynamics requires a paleoperspective. Here, we present an up-to-date synthesis of hydroclimatic variability over the past 30,000 years. A variety of terrestrial-based studies are examined and compared to understand patterns of regional hydroclimatic change. This comparison is extended into the San Joaquin Basin of California where future climate change will impact the region's agricultural stability and economy. Particularly interesting is the apparent role that Pacific sea surface temperatures (SSTs) play in modulating the region's hydroclimate over a variety of timescales. Are past periods of above average Pacific SSTs analogs for future global warming? If yes, the region might expect an increase in winter precipitation as SSTs rise in response to global warming. However, how this potential precipitation increase is manifest is unknown. For example, will the intensity of precipitation events increase and thus present increased flood hazards and diminished freshwater capture? Finally, we present evidence for changes in the source of winter precipitation over time as well as ecological responses to past hydrologic change.

A State-of-the-Art Review on Soil Reinforcement Technology Using Natural Plant Fiber Materials: Past Findings, Present Trends and Future Directions

PubMed Central

Gowthaman, Sivakumar; Nakashima, Kazunori; Kawasaki, Satoru

2018-01-01

Incorporating sustainable materials into geotechnical applications increases day by day due to the consideration of impacts on healthy geo-environment and future generations. The environmental issues associated with conventional synthetic materials such as cement, plastic-composites, steel and ashes necessitate alternative approaches in geotechnical engineering. Recently, natural fiber materials in place of synthetic material have gained momentum as an emulating soil-reinforcement technique in sustainable geotechnics. However, the natural fibers are innately different from such synthetic material whereas behavior of fiber-reinforced soil is influenced not only by physical-mechanical properties but also by biochemical properties. In the present review, the applicability of natural plant fibers as oriented distributed fiber-reinforced soil (ODFS) and randomly distributed fiber-reinforced soil (RDFS) are extensively discussed and emphasized the inspiration of RDFS based on the emerging trend. Review also attempts to explore the importance of biochemical composition of natural-fibers on the performance in subsoil reinforced conditions. The treatment methods which enhances the behavior and lifetime of fibers, are also presented. While outlining the current potential of fiber reinforcement technology, some key research gaps have been highlighted at their importance. Finally, the review briefly documents the future direction of the fiber reinforcement technology by associating bio-mediated technological line. PMID:29617285

Genetic toxicology in the 21st century: Reflections and future ...

EPA Pesticide Factsheets

A symposium at the 40th anniversary of the Environmental Mutagen Society, held from October 24–28, 2009 in St. Louis, MO, surveyed the current status and future directions of genetic toxicology. This article summarizes the presentations and provides a perspective on the future. An abbreviated history is presented, highlighting the current standard battery of genotoxicity assays and persistent challenges. Application of computational toxicology to safety testing within a regulatory setting is discussed as a means for reducing the need for animal testing and human clinical trials, and current approaches and applications of in silico genotoxicity screening approaches across the pharmaceutical industry were surveyed and are reported here. The expanded use of toxicogenomics to illuminate mechanisms and bridge genotoxicity and carcinogenicity, and new public efforts to use high-throughput screening technologies to address lack of toxicity evaluation for the backlog of thousands of industrial chemicals in the environment are detailed. The Tox21 project involves coordinated efforts of four U.S. Government regulatory/research entities to use new and innovative assays to characterize key steps in toxicity pathways, including genotoxic and nongenotoxic mechanisms for carcinogenesis. Progress to date, highlighting preliminary test results from the National Toxicology Program is summarized. Finally, an overview is presented of ToxCast™, a related research program of the

The γ p →p η η reaction in an effective Lagrangian model

NASA Astrophysics Data System (ADS)

Liu, Bo-Chao; Chen, Shao-Fei

2017-11-01

In this paper, we investigate the γ p →p η η reaction within an effective Lagrangian approach and isobar model. We consider the contributions from the intermediate N*(1535 ) , N*(1650 ) , N*(1710 ) , and N*(1720 ) isobars which finally decay to the N η state. It is found that the excitation of the N*(1535 ) dominates this reaction close to threshold and ρ meson exchange plays the most important role for the excitation of nucleon resonances. Therefore, this reaction offers a potentially good place to study the properties of nucleon resonances and their couplings to the N ρ channel. Predictions for angular distributions and invariant mass spectra of final particles are also presented for future comparison with data.

3D Printing, Additive Manufacturing, and Solid Freeform Fabrication: The Technologies of the Past, Present and Future

NASA Astrophysics Data System (ADS)

Beaman, Joseph

2015-03-01

Starting in the late 1980's, several new technologies were created that have the potential to revolutionize manufacturing. These technologies are, for the most part, additive processes that build up parts layer by layer. In addition, the processes that are being touted for hard-core manufacturing are primarily laser or e-beam based processes. This presentation gives a brief history of Additive Manufacturing and gives an assessment for these technologies. These technologies initially grew out of a commercial need for rapid prototyping. This market has a different requirement for process and quality control than traditional manufacturing. The relatively poor process control of the existing commercial Additive Manufacturing equipment is a vestige of this history. This presentation discusses this history and improvements in quality over time. The emphasis will be on Additive Manufacturing processes that are being considered for direct manufacturing, which is a different market than the 3D Printing ``Makerbot'' market. Topics discussed include past and present machine sensors, materials, and operational methods that were used in the past and those that are used today to create manufactured parts. Finally, a discussion of new methods and future directions of AM is presented.

Scan-layered reconstructions: A pilot study of a nondestructive dental histoanatomical analysis method and digital workflow to create restorations driven by natural dentin and enamel morphology.

PubMed

Malta Barbosa, João; Tovar, Nick; A Tuesta, Pablo; Hirata, Ronaldo; Guimarães, Nuno; Romanini, José C; Moghadam, Marjan; Coelho, Paulo G; Jahangiri, Leila

2017-07-08

This work aims to present a pilot study of a non-destructive dental histo-anatomical analysis technique as well as to push the boundaries of the presently available restorative workflows for the fabrication of highly customized ceramic restorations. An extracted human maxillary central incisor was subject to a micro computed tomography scan and the acquired data was transferred into a workstation, reconstructed, segmented, evaluated and later imported into a Computer-Aided Design/Computer-Aided Manufacturing software for the fabrication of a ceramic resin-bonded prosthesis. The obtained prosthesis presented an encouraging optical behavior and was used clinically as final restoration. The digitally layered restorative replication of natural tooth morphology presents today as a clear possibility. New clinical and laboratory-fabricated, biologically inspired digital restorative protocols are to be expected in the near future. The digitally layered restorative replication of natural tooth morphology presents today as a clear possibility. This pilot study may represent a stimulus for future research and applications of digital imaging as well as digital restorative workflows in service of esthetic dentistry. © 2017 Wiley Periodicals, Inc.

Galactic Surveys in the Gaia Era

NASA Astrophysics Data System (ADS)

Wyse, Rosemary F. G.

2018-04-01

The final astrometric data from the Gaia mission will transform our view of the stellar content of the Galaxy, particularly when complemented with spectroscopic surveys providing stellar parameters, line-of-sight kinematics and elemental abundances. Analyses with Gaia DR1 are already demonstrating the insight gained and the promise of what is to come with future Gaia releases. I present a brief overview of results and puzzles from recent Galactic Archaeology surveys for context, focusing on the Galactic discs.

Polymer Nanocomposites—A Comparison between Carbon Nanotubes, Graphene, and Clay as Nanofillers

PubMed Central

Bhattacharya, Mrinal

2016-01-01

Nanofilled polymeric matrices have demonstrated remarkable mechanical, electrical, and thermal properties. In this article we review the processing of carbon nanotube, graphene, and clay montmorillonite platelet as potential nanofillers to form nanocomposites. The various functionalization techniques of modifying the nanofillers to enable interaction with polymers are summarized. The importance of filler dispersion in the polymeric matrix is highlighted. Finally, the challenges and future outlook for nanofilled polymeric composites are presented. PMID:28773388

Hispanic-Americans and Business in the United States: Linking Up for a Stronger Future. Report of the Aspen Institute Conference "Hispanic-Americans and the Business Community" (Santa Barbara, CA, August 7-10, 1985).

ERIC Educational Resources Information Center

Aspen Inst. for Humanistic Studies, New York, NY.

In this report from the final session of a conference on Hispanic Americans and the business community, some general conclusions are presented. Participants, it is said, believed that the advancement of Hispanic-Americans in business depends on growing ties of mutual benefit between Hispanics and the general community. Despite the great attention…

Validation of Afterbody Aeroheating Predictions for Planetary Probes: Status and Future Work

NASA Technical Reports Server (NTRS)

Wright, Michael J.; Brown, James L.; Sinha, Krishnendu; Candler, Graham V.; Milos, Frank S.; Prabhu, DInesh K.

2005-01-01

A review of the relevant flight conditions and physical models for planetary probe afterbody aeroheating calculations is given. Readily available sources of afterbody flight data and published attempts to computationally simulate those flights are summarized. A current status of the application of turbulence models to afterbody flows is presented. Finally, recommendations for additional analysis and testing that would reduce our uncertainties in our ability to accurately predict base heating levels are given.

Enantioseparations by capillary electrochromatography.

PubMed

Fanali, S; Catarcini, P; Blaschke, G; Chankvetadze, B

2001-09-01

The review summarizes recent developments in enantioseparations by capillary electrochromatography (CEC). Selected fundamental aspects of CEC are discussed in order to stress those features which may allow the success of this technique in the competitive field of enantioseparations. In addition, the comparative characteristics of the different modes of chiral CEC and the stationary phases are presented. The effects of the characteristics of the stationary and liquid phases and operational conditions on the separation results are discussed. Finally, some future trends are briefly addressed.

National Academy of Sciences and Academy of Sciences of the USSR workshop on structure of the eucaryotic genome and regulation of its expression. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1990-12-31

This report provides a brief overview of the Workshop on Structure of the Eukaryotic Genome and Regulation of its Expression held in Tbilisi, Georgia, USSR. The report describes the presentations made at the meeting but also goes on to describe the state of molecular biology and genetics research in the Soviet Union and makes recommendations on how to improve future such meetings.

Calibration sources and filters of the soft x-ray spectrometer instrument on the Hitomi spacecraft

NASA Astrophysics Data System (ADS)

de Vries, Cor P.; Haas, Daniel; Yamasaki, Noriko Y.; Herder, Jan-Willem den; Paltani, Stephane; Kilbourne, Caroline; Tsujimoto, Masahiro; Eckart, Megan E.; Leutenegger, Maurice A.; Costantini, Elisa; Dercksen, Johannes P. C.; Dubbeldam, Luc; Frericks, Martin; Laubert, Phillip P.; van Loon, Sander; Lowes, Paul; McCalden, Alec J.; Porter, Frederick S.; Ruijter, Jos; Wolfs, Rob

2018-01-01

The soft x-ray spectrometer was designed to operate onboard the Japanese Hitomi (ASTRO-H) satellite. In the beam of this instrument, there was a filter wheel containing x-ray filters and active calibration sources. This paper describes this filter wheel. We show the purpose of the filters and the preflight calibrations performed. In addition, we present the calibration source design and measured performance. Finally, we conclude with prospects for future missions.

Engineered human vaccines

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sandhu, J.S.

1994-01-01

The limitations of human vaccines in use at present and the design requirements for a new generation of human vaccines are discussed. The progress in engineering of human vaccines for bacteria, viruses, parasites, and cancer is reviewed, and the data from human studies with the engineered vaccines are discussed, especially for cancer and AIDS vaccines. The final section of the review deals with the possible future developments in the field of engineered human vaccines and the requirement for effective new human adjuvants.

An Analysis of Computer Aided Design (CAD) Packages Used at MSFC for the Recent Initiative to Integrate Engineering Activities

NASA Technical Reports Server (NTRS)

Smith, Leigh M.; Parker, Nelson C. (Technical Monitor)

2002-01-01

This paper analyzes the use of Computer Aided Design (CAD) packages at NASA's Marshall Space Flight Center (MSFC). It examines the effectiveness of recent efforts to standardize CAD practices across MSFC engineering activities. An assessment of the roles played by management, designers, analysts, and manufacturers in this initiative will be explored. Finally, solutions are presented for better integration of CAD across MSFC in the future.

Overview of Petroleum Settings in Deep Waters of the Brazilian South Atlantic Margin

NASA Astrophysics Data System (ADS)

Anjos, Sylvia; Penteado, Henrique; Oliveira, Carlos M. M.

2015-04-01

The objective of this work is to present an overall view of the tectonic and stratigraphic evolution of the western South Atlantic with focus on the Brazilian marginal basins. It includes the structural evolution, stratigraphic sequences, depositional environments and petroleum systems model along the Brazilian marginal basins. In addition, a description of the main petroleum provinces and selected plays including the pre-salt carbonates and post-salt turbidite reservoirs is presented. Source-rock ages and types, trap styles, main reservoir characteristics, petroleum compositions, and recent exploration results are discussed. Finally, an outlook and general assessment of the impact of the large pre-salt discoveries on the present-day and future production curves are given.

Application of geostatistics to coal-resource characterization and mine planning. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kauffman, P.W.; Walton, D.R.; Martuneac, L.

1981-12-01

Geostatistics is a proven method of ore reserve estimation in many non-coal mining areas but little has been published concerning its application to coal resources. This report presents the case for using geostatistics for coal mining applications and describes how a coal mining concern can best utilize geostatistical techniques for coal resource characterization and mine planning. An overview of the theory of geostatistics is also presented. Many of the applications discussed are documented in case studies that are a part of the report. The results of an exhaustive literature search are presented and recommendations are made for needed future researchmore » and demonstration projects.« less

Evaluation of laminar flow control system concepts for subsonic commercial transport aircraft

NASA Technical Reports Server (NTRS)

1978-01-01

A two-year study conducted to establish a basis for industry decisions on the application of laminar flow control (LFC) to future commercial transports was presented. Areas of investigation included: (1) mission definition and baseline selection; (2) concepts evaluations; and (3) LFC transport configuration selection and component design. The development and evaluation of competing design concepts was conducted in the areas of aerodynamics, structures and materials, and systems. The results of supporting wind tunnel and laboratory testing on a full-scale LFC wing panel, suction surface opening concepts and structural samples were included. A final LFC transport was configured in incorporating the results of concept evaluation studies and potential performance improvements were assessed. Remaining problems together with recommendations for future research are discussed.

Analysis and interpretation of the 1985 Sequoia transport experiment. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Myrup, L.; Flocchini, R.

1987-10-01

An analysis and interpretation is presented of the 1985 Aerosol Transport and Characterization Program at Sequoia National Park, sponsored by the California Air Resources Board. Overall, it was found that the Program produced unique data sets and interesting new results relating particulate air quality and meteorology in the context of complex terrain. The major conclusion is that the meso-scale wind field, as modulated by synoptic-scale fluctuations, is the chief factor acting to cause variation in particulate concentrations in the Park. Areas for future work are discussed. In addition, it was recommended that in future measurement programs, greater effort be mademore » to locate sites completely unaffected by local sources of pollutants.« less

Quantitative imaging of volcanic plumes — Results, needs, and future trends

USGS Publications Warehouse

Platt, Ulrich; Lübcke, Peter; Kuhn, Jonas; Bobrowski, Nicole; Prata, Fred; Burton, Mike; Kern, Christoph

2015-01-01

Recent technology allows two-dimensional “imaging” of trace gas distributions in plumes. In contrast to older, one-dimensional remote sensing techniques, that are only capable of measuring total column densities, the new imaging methods give insight into details of transport and mixing processes as well as chemical transformation within plumes. We give an overview of gas imaging techniques already being applied at volcanoes (SO2cameras, imaging DOAS, FT-IR imaging), present techniques where first field experiments were conducted (LED-LIDAR, tomographic mapping), and describe some techniques where only theoretical studies with application to volcanology exist (e.g. Fabry–Pérot Imaging, Gas Correlation Spectroscopy, bi-static LIDAR). Finally, we discuss current needs and future trends in imaging technology.

Microarray expression technology: from start to finish.

PubMed

Elvidge, Gareth

2006-01-01

The recent introduction of new microarray expression technologies and the further development of established platforms ensure that the researcher is presented with a range of options for performing an experiment. Whilst this has opened up the possibilities for future applications, such as exon-specific arrays, increased sample throughput and 'chromatin immunoprecipitation (ChIP) on chip' experiments, the initial decision processes and experiment planning are made more difficult. This review will give an overview of the various technologies that are available to perform a microarray expression experiment, from the initial planning stages through to the final data analysis. Both practical aspects and data analysis options will be considered. The relative advantages and disadvantages will be discussed with insights provided for future directions of the technology.

Infection prevention behaviour and infectious disease modelling: a review of the literature and recommendations for the future.

PubMed

Weston, Dale; Hauck, Katharina; Amlôt, Richard

2018-03-09

Given the importance of person to person transmission in the spread of infectious diseases, it is critically important to ensure that human behaviour with respect to infection prevention is appropriately represented within infectious disease models. This paper presents a large scale scoping review regarding the incorporation of infection prevention behaviour in infectious disease models. The outcomes of this review are contextualised within the psychological literature concerning health behaviour and behaviour change, resulting in a series of key recommendations for the incorporation of human behaviour in future infectious disease models. The search strategy focused on terms relating to behaviour, infectious disease and mathematical modelling. The selection criteria were developed iteratively to focus on original research articles that present an infectious disease model with human-human spread, in which individuals' self-protective health behaviour varied endogenously within the model. Data extracted included: the behaviour that is modelled; how this behaviour is modelled; any theoretical background for the modelling of behaviour, and; any behavioural data used to parameterise the models. Forty-two papers from an initial total of 2987 were retained for inclusion in the final review. All of these papers were published between 2002 and 2015. Many of the included papers employed a multiple, linked models to incorporate infection prevention behaviour. Both cognitive constructs (e.g., perceived risk) and, to a lesser extent, social constructs (e.g., social norms) were identified in the included papers. However, only five papers made explicit reference to psychological health behaviour change theories. Finally, just under half of the included papers incorporated behavioural data in their modelling. By contextualising the review outcomes within the psychological literature on health behaviour and behaviour change, three key recommendations for future behavioural modelling are made. First, modellers should consult with the psychological literature on health behaviour/ behaviour change when developing new models. Second, modellers interested in exploring the relationship between behaviour and disease spread should draw on social psychological literature to increase the complexity of the social world represented within infectious disease models. Finally, greater use of context-specific behavioural data (e.g., survey data, observational data) is recommended to parameterise models.

Future Aeronautical Communication Infrastructure Technology Investigation

NASA Technical Reports Server (NTRS)

Gilbert, Tricia; Jin, Jenny; Bergerm Jason; Henriksen, Steven

2008-01-01

This National Aeronautics and Space Administration (NASA) Contractor Report summarizes and documents the work performed to investigate technologies that could support long-term aeronautical mobile communications operating concepts for air traffic management (ATM) in the timeframe of 2020 and beyond, and includes the associated findings and recommendations made by ITT Corporation and NASA Glenn Research Center to the Federal Aviation Administration (FAA). The work was completed as the final phase of a multiyear NASA contract in support of the Future Communication Study (FCS), a cooperative research and development program of the United States FAA, NASA, and EUROCONTROL. This final report focuses on an assessment of final five candidate technologies, and also provides an overview of the entire technology assessment process, including final recommendations.

Acquisition and Development of a Cognitive Radio Based Wireless Monitoring and Surveillance Testbed for Future Battlefield Communications Research

DTIC Science & Technology

2015-03-01

for Public Release; Distribution Unlimited Final Report: Acquisition and Development of A Cognitive Radio based Wireless Monitoring and Surveillance...journals: Final Report: Acquisition and Development of A Cognitive Radio based Wireless Monitoring and Surveillance Testbed for Future Battlefield...Opeyemi Oduola, Nan Zou, Xiangfang Li, Husheng Li, Lijun Qian. Distributed Spectrum Monitoring and Surveillance using a Cognitive Radio based Testbed

15 CFR 990.63 - Discounting and compounding.

Code of Federal Regulations, 2010 CFR

2010-01-01

... NATURAL RESOURCE DAMAGE ASSESSMENTS Restoration Implementation Phase § 990.63 Discounting and compounding. (a) Estimated future restoration costs. When determining estimated future costs of implementing a Final Restoration Plan, trustees must discount such future costs back to the date the demand is...

17 CFR 8.20 - Final decision.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Final decision. 8.20 Section 8.20 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXCHANGE PROCEDURES FOR DISCIPLINARY, SUMMARY, AND MEMBERSHIP DENIAL ACTIONS Disciplinary Procedure § 8.20 Final decision. Each...

Double-parton scattering effects in D0B+ and B+B+ meson-meson pair production in proton-proton collisions at the LHC

NASA Astrophysics Data System (ADS)

Maciuła, Rafał; Szczurek, Antoni

2018-05-01

We extend our previous studies of double-parton scattering (DPS) to simultaneous production of c c ¯ and b b ¯ and production of two pairs of b b ¯. The calculation is performed within a factorized ansatz. Each parton scattering is calculated within the kT-factorization approach. The hadronization is done with the help of fragmentation functions. Production of D mesons in our framework was tested in our previous works. Here, we present our predictions for B mesons. A good agreement is achieved with the LHCb data. We present our results for c c ¯b b ¯ and b b ¯b b ¯ final states. For completeness, we compare results for double- and single-parton scattering (SPS). As for the c c ¯c c ¯ final state, the DPS dominates over the SPS, especially for small transverse momenta. We present several distributions and integrated cross sections with realistic cuts for simultaneous production of D0B+ and B+B+, suggesting future experimental studies at the LHC.

Can future land use change be usefully predicted?

NASA Astrophysics Data System (ADS)

Ramankutty, N.; Coomes, O.

2011-12-01

There has been increasing recognition over the last decade that land use and land cover change is an important driver of global environmental change. Consequently, there have been growing efforts to understanding processes of land change from local-to-global scales, and to develop models to predict future changes in the land. However, we believe that such efforts are hampered by limited attention being paid to the critical points of land change. Here, we present a framework for understanding land use change by distinguishing within-regime land-use dynamics from land-use regime shifts. Illustrative historical examples reveal the significance of land-use regime shifts. We further argue that the land-use literature predominantly demonstrates a good understanding (with predictive power) of within-regime dynamics, while understanding of land-use regime shifts is limited to ex post facto explanations with limited predictive capability. The focus of land use change science needs to be redirected toward studying land-use regime shifts if we are to have any hope of making useful future projections. We present a preliminary framework for understanding land-use regime-shifts, using two case studies in Latin America as examples. We finally discuss the implications of our proposal for land change science.

UROLOGIC ROBOTS AND FUTURE DIRECTIONS

PubMed Central

Mozer, Pierre; Troccaz, Jocelyne; Stoianovici, Dan

2009-01-01

Purpose of review Robot-assisted laparoscopic surgery in urology has gained immense popularity with the Da Vinci system but a lot of research teams are working on new robots. The purpose of this paper is to review current urologic robots and present future developments directions. Recent findings Future systems are expected to advance in two directions: improvements of remote manipulation robots and developments of image-guided robots. Summary The final goal of robots is to allow safer and more homogeneous outcomes with less variability of surgeon performance, as well as new tools to perform tasks based on medical transcutaneous imaging, in a less invasive way, at lower costs. It is expected that improvements for remote system could be augmented reality, haptic feed back, size reduction and development of new tools for NOTES surgery. The paradigm of image-guided robots is close to a clinical availability and the most advanced robots are presented with end-user technical assessments. It is also notable that the potential of robots lies much further ahead than the accomplishments of the daVinci system. The integration of imaging with robotics holds a substantial promise, because this can accomplish tasks otherwise impossible. Image guided robots have the potential to offer a paradigm shift. PMID:19057227

Urologic robots and future directions.

PubMed

Mozer, Pierre; Troccaz, Jocelyne; Stoianovici, Dan

2009-01-01

Robot-assisted laparoscopic surgery in urology has gained immense popularity with the daVinci system, but a lot of research teams are working on new robots. The purpose of this study is to review current urologic robots and present future development directions. Future systems are expected to advance in two directions: improvements of remote manipulation robots and developments of image-guided robots. The final goal of robots is to allow safer and more homogeneous outcomes with less variability of surgeon performance, as well as new tools to perform tasks on the basis of medical transcutaneous imaging, in a less invasive way, at lower costs. It is expected that improvements for a remote system could be augmented in reality, with haptic feedback, size reduction, and development of new tools for natural orifice translumenal endoscopic surgery. The paradigm of image-guided robots is close to clinical availability and the most advanced robots are presented with end-user technical assessments. It is also notable that the potential of robots lies much further ahead than the accomplishments of the daVinci system. The integration of imaging with robotics holds a substantial promise, because this can accomplish tasks otherwise impossible. Image-guided robots have the potential to offer a paradigm shift.

On-road vehicle detection: a review.

PubMed

Sun, Zehang; Bebis, George; Miller, Ronald

2006-05-01

Developing on-board automotive driver assistance systems aiming to alert drivers about driving environments, and possible collision with other vehicles has attracted a lot of attention lately. In these systems, robust and reliable vehicle detection is a critical step. This paper presents a review of recent vision-based on-road vehicle detection systems. Our focus is on systems where the camera is mounted on the vehicle rather than being fixed such as in traffic/driveway monitoring systems. First, we discuss the problem of on-road vehicle detection using optical sensors followed by a brief review of intelligent vehicle research worldwide. Then, we discuss active and passive sensors to set the stage for vision-based vehicle detection. Methods aiming to quickly hypothesize the location of vehicles in an image as well as to verify the hypothesized locations are reviewed next. Integrating detection with tracking is also reviewed to illustrate the benefits of exploiting temporal continuity for vehicle detection. Finally, we present a critical overview of the methods discussed, we assess their potential for future deployment, and we present directions for future research.

Integrated Framework for an Urban Climate Adaptation Tool

NASA Astrophysics Data System (ADS)

Omitaomu, O.; Parish, E. S.; Nugent, P.; Mei, R.; Sylvester, L.; Ernst, K.; Absar, M.

2015-12-01

Cities have an opportunity to become more resilient to future climate change through investments made in urban infrastructure today. However, most cities lack access to credible high-resolution climate change projection information needed to assess and address potential vulnerabilities from future climate variability. Therefore, we present an integrated framework for developing an urban climate adaptation tool (Urban-CAT). Urban-CAT consists of four modules. Firstly, it provides climate projections at different spatial resolutions for quantifying urban landscape. Secondly, this projected data is combined with socio-economic data using leading and lagging indicators for assessing landscape vulnerability to climate extremes (e.g., urban flooding). Thirdly, a neighborhood scale modeling approach is presented for identifying candidate areas for adaptation strategies (e.g., green infrastructure as an adaptation strategy for urban flooding). Finally, all these capabilities are made available as a web-based tool to support decision-making and communication at the neighborhood and city levels. In this paper, we present some of the methods that drive each of the modules and demo some of the capabilities available to-date using the City of Knoxville in Tennessee as a case study.

The revision of the Declaration of Helsinki: past, present and future.

PubMed

Carlson, Robert V; Boyd, Kenneth M; Webb, David J

2004-06-01

The World Medical Association's Declaration of Helsinki was first adopted in 1964. In its 40-year lifetime the Declaration has been revised five times and has risen to a position of prominence as a guiding statement of ethical principles for doctors involved in medical research. The most recent revision, however, has resulted in considerable controversy, particularly in the area of the ethical requirements surrounding placebo-controlled trials and the question of responsibilities to research participants at the end of a study. This review considers the past versions of the Declaration of Helsinki and asks the question: How exactly has the text of the Declaration changed throughout its lifetime? Regarding the present form of the Declaration of Helsinki we ask: What are the major changes in the most recent revision and what are the controversies surrounding them? Finally, building on the detailed review of the past and present versions of the Declaration of Helsinki, we give consideration to some of the possible future trajectories for the Declaration in the light of its history and standing in the world of the ethics of medical research.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hudson, S.R.

This report presents the results of a four-day symposium which reviewed the state-of-the-art, field testing and recent progress in underground coal conversion. The symposium was held at Keystone Lodge, Colorado, August 15-19, 1982, and was sponsored by the US Department of Energy and hosted by Sandia National Laboratories. Over 100 attendees participated in this seminar which offered more than 60 presentations in both poster and oral sessions on The Status of UCC Technology, Achievements and Problems of UCC, Future R and D Activities, and Roles and Outlooks, for an overall theme of Where Do We Go From Here. This symposiummore » was structured to deal with an evaluation of the present uncertainty in future federal funding of UCC. Panel discussions were held after each oral session to address this overall question. The final session of the symposium was a summary session reflecting the thoughts of all panelists and symposium speakers. This session also serves as our Executive Summary (page 567). Forty-one papers have been entered individually into EDB and ERA; twelve papers had been entered previously. (LTN)« less

17 CFR 8.28 - Final decision.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Final decision. 8.28 Section 8.28 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXCHANGE PROCEDURES FOR DISCIPLINARY, SUMMARY, AND MEMBERSHIP DENIAL ACTIONS Summary Actions § 8.28 Final decision. Each exchange shall...

Utilization of case presentations in medical microbiology to enhance relevance of basic science for medical students.

PubMed

Chamberlain, Neal R; Stuart, Melissa K; Singh, Vineet K; Sargentini, Neil J

2012-01-01

Small-group case presentation exercises (CPs) were created to increase course relevance for medical students taking Medical Microbiology (MM) and Infectious Diseases (ID) METHODS: Each student received a unique paper case and had 10 minutes to review patient history, physical exam data, and laboratory data. Students then had three minutes to orally present their case and defend why they ruled in or out each of the answer choices provided, followed by an additional three minutes to answer questions. Exam scores differed significantly between students who received the traditional lecture-laboratory curriculum (Group I) and students who participated in the CPs (Group II). In MM, median unit exam and final exam scores for Group I students were 84.4% and 77.8%, compared to 86.0% and 82.2% for Group II students (P<0.018; P<0.001; Mann-Whitney Rank Sum Test). Median unit and final ID exam scores for Group I students were 84.0% and 80.0%, compared to 88.0% and 86.7% for Group II students (P<0.001; P<0.001). Students felt that the CPs improved their critical thinking and presentation skills and helped to prepare them as future physicians.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Millar, A. P.; Baranova, T.; Behrmann, G.

For over a decade, dCache has been synonymous with large-capacity, fault-tolerant storage using commodity hardware that supports seamless data migration to and from tape. In this paper we provide some recent news of changes within dCache and the community surrounding it. We describe the flexible nature of dCache that allows both externally developed enhancements to dCache facilities and the adoption of new technologies. Finally, we present information about avenues the dCache team is exploring for possible future improvements in dCache.

A Classification Scheme for Smart Manufacturing Systems’ Performance Metrics

PubMed Central

Lee, Y. Tina; Kumaraguru, Senthilkumaran; Jain, Sanjay; Robinson, Stefanie; Helu, Moneer; Hatim, Qais Y.; Rachuri, Sudarsan; Dornfeld, David; Saldana, Christopher J.; Kumara, Soundar

2017-01-01

This paper proposes a classification scheme for performance metrics for smart manufacturing systems. The discussion focuses on three such metrics: agility, asset utilization, and sustainability. For each of these metrics, we discuss classification themes, which we then use to develop a generalized classification scheme. In addition to the themes, we discuss a conceptual model that may form the basis for the information necessary for performance evaluations. Finally, we present future challenges in developing robust, performance-measurement systems for real-time, data-intensive enterprises. PMID:28785744

Anaerobic digestion of organic solid poultry slaughterhouse waste--a review.

PubMed

Salminen, E; Rintala, J

2002-05-01

This work reviews the potential of anaerobic digestion for material recovery and energy production from poultry slaughtering by-products and wastes. First, we describe and quantify organic solid by-products and wastes produced in poultry farming and poultry slaughterhouses and discuss their recovery and disposal options. Then we review certain fundamental aspects of anaerobic digestion considered important for the digestion of solid slaughterhouse wastes. Finally, we present an overview of the future potential and current experience of the anaerobic digestion treatment of these materials.

Nanonization strategies for poorly water-soluble drugs.

PubMed

Chen, Huabing; Khemtong, Chalermchai; Yang, Xiangliang; Chang, Xueling; Gao, Jinming

2011-04-01

Poor water solubility for many drugs and drug candidates remains a major obstacle to their development and clinical application. Conventional formulations to improve solubility suffer from low bioavailability and poor pharmacokinetics, with some carriers rendering systemic toxicities (e.g. Cremophor(®) EL). In this review, several major nanonization techniques that seek to overcome these limitations for drug solubilization are presented. Strategies including drug nanocrystals, nanoemulsions and polymeric micelles are reviewed. Finally, perspectives on existing challenges and future opportunities are highlighted. Published by Elsevier Ltd.

Electrolytic hydrogen production: An analysis and review

NASA Technical Reports Server (NTRS)

Evangelista, J.; Phillips, B.; Gordon, L.

1975-01-01

The thermodynamics of water electrolysis cells is presented, followed by a review of current and future technology of commercial cells. The irreversibilities involved are analyzed and the resulting equations assembled into a computer simulation model of electrolysis cell efficiency. The model is tested by comparing predictions based on the model to actual commercial cell performance, and a parametric investigation of operating conditions is performed. Finally, the simulation model is applied to a study of electrolysis cell dynamics through consideration of an ideal pulsed electrolyzer.

Characteristic classes, singular embeddings, and intersection homology.

PubMed

Cappell, S E; Shaneson, J L

1987-06-01

This note announces some results on the relationship between global invariants and local topological structure. The first section gives a local-global formula for Pontrjagin classes or L-classes. The second section describes a corresponding decomposition theorem on the level of complexes of sheaves. A final section mentions some related aspects of "singular knot theory" and the study of nonisolated singularities. Analogous equivariant analogues, with local-global formulas for Atiyah-Singer classes and their relations to G-signatures, will be presented in a future paper.

Diode-Pumped, 2-Micron, Q-Switched Thulium: Y3Al5O12 (Tm:Yag) Microchip Laser

DTIC Science & Technology

2011-05-01

switch with a chromium -doped zinc selenide crystal acting as a saturable absorber passive Q-switch. Finally, we will propose possible future...literature by Heine and Huber [4] and others, while passive Q-switching of 2 μm lasers by a chromium -doped zinc selenide has been demonstrated by Tsai and...these objectives for each component of the laser system. In Chapter 4 a design is presented for replacing our acousto-optic Q-switch with a chromium

Managing laboratory automation

PubMed Central

Saboe, Thomas J.

1995-01-01

This paper discusses the process of managing automated systems through their life cycles within the quality-control (QC) laboratory environment. The focus is on the process of directing and managing the evolving automation of a laboratory; system examples are given. The author shows how both task and data systems have evolved, and how they interrelate. A BIG picture, or continuum view, is presented and some of the reasons for success or failure of the various examples cited are explored. Finally, some comments on future automation need are discussed. PMID:18925018

Software management tools: Lessons learned from use

NASA Technical Reports Server (NTRS)

Reifer, D. J.; Valett, J.; Knight, J.; Wenneson, G.

1985-01-01

Experience in inserting software project planning tools into more than 100 projects producing mission critical software are discussed. The problems the software project manager faces are listed along with methods and tools available to handle them. Experience is reported with the Project Manager's Workstation (PMW) and the SoftCost-R cost estimating package. Finally, the results of a survey, which looked at what could be done in the future to overcome the problems experienced and build a set of truly useful tools, are presented.

San Antonio I Software Workshop Proceedings. DoD Software for the 1990s, Held in San Antonio, Texas on 28 January - 1 February 1991

DTIC Science & Technology

1991-12-01

management and engineering issues common to the military-industrial complex, - to learn from past experience, - to understand future software...prospective policy documents. - :Prepare a draft issue paper and presentation for the DAE. These items should address the key implementation issues with...respect to MCCR software metrics and establish a clear need for DAE support. Long Term Actions ( past 12-18 mcnths) ... Draft final implementation

Comparative lahar hazard mapping at Volcan Citlaltépetl, Mexico using SRTM, ASTER and DTED-1 digital topographic data

USGS Publications Warehouse

Hubbard, Bernard E.; Sheridan, Michael F.; Carrasco-Nunez, Gerardo; Diaz-Castellon, Rodolfo; Rodriguez, Sergio R.

2007-01-01

Finally, ASTERs 60 km swath width and 8% duty cycle presents a challenge for mapping lahar inundation hazards at E–W oriented stream valleys in low-latitude areas with persistent cloud cover. However, its continued operations enhances its utility as a means for updating the continuous but one-time coverage of SRTM, and for filling voids in the SRTM dataset such as those that occur along steep-sided valleys prone to hazards from future lahars.

Combat aircraft noise

NASA Astrophysics Data System (ADS)

Sgarbozza, M.; Depitre, A.

1992-04-01

A discussion of the characteristics and the noise levels of combat aircraft and of a transport aircraft in taking off and landing are presented. Some methods of noise reduction are discussed, including the following: operational anti-noise procedures; and concepts of future engines (silent post-combustion and variable cycle). Some measurement results concerning the noise generated in flight at great speeds and low altitude will also be examined. Finally, the protection of the environment of French air bases against noise will be described and the possibilities of regulation examined.

The Observing Time Distribution in Major Groundbased Observatories - a Complex Task

NASA Astrophysics Data System (ADS)

Breysacher, J.

The aim of the present paper is to give, first, a brief description of the different steps related to the general procedure of telescope time allocation at the European Southern Observatory, and then, a detailed review of the various constraints one has to take into account when preparing the final observing schedule on the various telescopes installed at La Silla. A succinct discussion will be given of how, in the future, remote control observing may facilitate the coordination of multiwavelength investigations.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Katz, Ulrich F., E-mail: katz@physik.uni-erlangen.de; Collaboration: KM3NeT Collaboration

KM3NeT is a future research infrastructure in the Mediterranean Sea, hosting a multi-cubic-kilometre neutrino telescope and nodes for Earth and Sea sciences. In this report we shortly summarise the genesis of the KM3NeT project and present key elements of its technical design. The physics objectives of the KM3NeT neutrino telescope and some selected sensitivity estimates are discussed. Finally, some first results from prototype operations and the next steps towards implementation – in particular the first construction phase in 2014/15 – are described.

Managing laboratory automation.

PubMed

Saboe, T J

1995-01-01

This paper discusses the process of managing automated systems through their life cycles within the quality-control (QC) laboratory environment. The focus is on the process of directing and managing the evolving automation of a laboratory; system examples are given. The author shows how both task and data systems have evolved, and how they interrelate. A BIG picture, or continuum view, is presented and some of the reasons for success or failure of the various examples cited are explored. Finally, some comments on future automation need are discussed.

Contractor for geopressured-geothermal sites: Final contract report, Volume 1, fiscal years 1986--1990 (5 years), testing of wells through October 1990. Appendix A, Volume 2, Gladys McCall Site (Cameron Parish LA); Appendix B-1, Volume 3, Pleasant Bayou Site; Appendix B-2, Volume 4, Pleasant Bayou Site; Appendix C, Volume 5, Willis Hulin Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1992-09-01

Field tests and studies were conducted to determine the production behavior of geopressured-geothermal reservoirs and their potential as future energy sources. Results are presented for Gladys McCall Site, Pleasant Bayou Site, and Hulin Site.

Modular neural networks: a survey.

PubMed

Auda, G; Kamel, M

1999-04-01

Modular Neural Networks (MNNs) is a rapidly growing field in artificial Neural Networks (NNs) research. This paper surveys the different motivations for creating MNNs: biological, psychological, hardware, and computational. Then, the general stages of MNN design are outlined and surveyed as well, viz., task decomposition techniques, learning schemes and multi-module decision-making strategies. Advantages and disadvantages of the surveyed methods are pointed out, and an assessment with respect to practical potential is provided. Finally, some general recommendations for future designs are presented.

Open Forum on Optimizing Communication Amongst Astronomy Librarians in the Digital Age

NASA Astrophysics Data System (ADS)

Regan, Jeanette

Conferences are held to enhance communication between colleagues. This final session of LISA III was presented as the opportunity for participants, as well as those unable to attend, to express their concerns and to make comments or suggestions regarding future communication amongst astronomy librarians, publishers and researchers. A list of discussion topics was distributed both at the conference and by email (on Astrolib) so that responses could be made either in person or in written form.

Mind matters: cognitive and physical effects of aging self-stereotypes.

PubMed

Levy, Becca R

2003-07-01

In the first part of this article, a wide range of research is drawn upon to describe the process by which aging stereotypes are internalized in younger individuals and then become self-stereotypes when individuals reach old age. The second part consists of a review of the author's cross-cultural, experimental, and longitudinal research that examines the cognitive and physical effects of aging self-stereotypes. The final section presents suggestions for future research relating to aging self-stereotypes.

First results from the Airborne Visible/Infrared Imaging Spectrometer (AVIRIS)

NASA Technical Reports Server (NTRS)

Vane, Gregg

1987-01-01

After engineering flights aboard the NASA U-2 research aircraft in the winter of 1986 to 1987 and spring of 1987, extensive data collection across the United States was begun with the Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) in the summer of 1987 in support of a NASA data evaluation and technology assessment program. This paper presents some of the first results obtained from AVIRIS. Examples of spectral imagery acquired over Mountain View and Mono Lake, California, and the Cuprite Mining District in western Nevada are presented. Sensor performance and data quality are described, and in the final section of this paper, plans for the future are discussed.

Application and future of solid foams

NASA Astrophysics Data System (ADS)

Bienvenu, Yves

2014-10-01

To conclude this series of chapters on solid foam materials, a review of industrial current applications and of mid-term market perspectives centred on manmade foams is given, making reference to natural cellular materials. Although the polymeric foam industrial development overwhelms the rest and finds applications on many market segments, more attention will be paid to the emerging market of inorganic-especially metallic-foams (and cellular materials) and their applications, present or upcoming. It is shown that the final applications of solid foams are primarily linked to transport and the present-day development of the different classes of solid foams is contrasted between functional applications and structural applications. xml:lang="fr"

CCD radiation damage in ESA Cosmic Visions missions: assessment and mitigation

NASA Astrophysics Data System (ADS)

Lumb, David H.

2009-08-01

Charge Coupled Device (CCD) imagers have been widely used in space-borne astronomical instruments. A frequent concern has been the radiation damage effects on the CCD charge transfer properties. We review some methods for assessing the Charge Transfer Inefficiency (CTI) in CCDs. Techniques to minimise degradation using background charge injection and p-channel CCD architectures are discussed. A critical review of the claims for p-channel architectures is presented. The performance advantage for p-channel CCD performance is shown to be lower than claimed previously. Finally we present some projections for the performance in the context of some future ESA missions.

Veritas Asteroid Family Still Holds Secrets?

NASA Astrophysics Data System (ADS)

Novakovic, B.

2012-12-01

Veritas asteroid family has been studied for about two decades. These studies have revealed many secrets, and a respectable knowledge about this family had been collected. Here I will present many of these results and review the current knowledge about the family. However, despite being extensively studied, Veritas family is still a mystery. This will be illustrated through the presentation of the most interesting open problems. Was there a secondary collision within this family? Does asteroid (490) Veritas belong to the family named after it? How large was the parent body of the family? Finally, some possible directions for future studies that aims to address these questions are discussed as well.

Temperament and Personality in Bariatric Surgery-Resisting Temptations?

PubMed

Claes, Laurence; Müller, Astrid

2015-11-01

Temperament and personality traits can serve as both risk factors as well as protective factors in the development of morbid obesity. In the present review, we present an overview of studies focusing on the relationship between temperament/personality and morbid obesity in pre-operative and postoperative bariatric surgery patients. We consider studies that focus on both a categorical and dimensional point of view on temperament/personality, as well as studies based on cross-sectional and longitudinal designs. Finally, we will integrate the research findings, discuss the implications for assessment and treatment and formulate suggestions for future research. Copyright © 2015 John Wiley & Sons, Ltd and Eating Disorders Association.

Mission operations systems for planetary exploration

NASA Technical Reports Server (NTRS)

Mclaughlin, William I.; Wolff, Donna M.

1988-01-01

The purpose of the paper is twofold: (1) to present an overview of the processes comprising planetary mission operations as conducted at the Jet Propulsion Laboratory, and (2) to present a project-specific and historical context within which this evolving process functions. In order to accomplish these objectives, the generic uplink and downlink functions are described along with their specialization to current flight projects. Also, new multimission capabilities are outlined, including prototyping of advanced-capability software for subsequent incorporation into more automated future operations. Finally, a specific historical ground is provided by listing some major operations software plus a genealogy of planetary missions beginning with Mariner 2 in 1962.

Communications payload concepts for geostationary facilities

NASA Technical Reports Server (NTRS)

Poley, William A.; Lekan, Jack

1987-01-01

Summarized and compared are the major results of two NASA sponsored studies that defined potential communication payload concepts to meet the satellite traffic forecast for the turn of the century for the continental US and Region 2 of the International Telecommunications Union. The studies were performed by the Ford Aerospace and Communications Corporation and RCA Astro-Electronics (now GE-RCA Astro-Space Division). Future scenarios of aggregations of communications services are presented. Payload concepts are developed and defined in detail for nine of the scenarios. Payload costs and critical technologies per payload are also presented. Finally the payload concepts are compared and the findings of the reports are discussed.

Remote Sensing of Drought: Progress and Opportunities for Improving Drought Monitoring and Prediction

NASA Astrophysics Data System (ADS)

AghaKouchak, A.; Huning, L. S.; Love, C. A.; Farahmand, A.

2017-12-01

This presentation surveys current and emerging drought monitoring approaches using satellite remote sensing observations from climatological and ecosystem perspectives. Satellite observations that are not currently used for operational drought monitoring, such as near-surface air relative humidity and water vapor, provide opportunities to improve early drought warning. Current and future satellite missions offer opportunities to develop composite and multi-indicator drought models. This presentation describes how different satellite observations can be combined for overall drought development and impact assessment. Finally, we provide an overview of the research gaps and challenges that are facing us ahead in the remote sensing of drought.

The FRUITY database on AGB stars: past, present and future

NASA Astrophysics Data System (ADS)

Cristallo, S.; Piersanti, L.; Straniero, O.

2016-01-01

We present and show the features of the FRUITY database, an interactive web- based interface devoted to the nucleosynthesis in AGB stars. We describe the current available set of AGB models (largely expanded with respect to the original one) with masses in the range 1.3≤M/M⊙≤3.0 and metallicities -2.15 ≤[Fe/H]≤+0.15. We illustrate the details of our s-process surface distributions and we compare our results to observations. Moreover, we introduce a new set of models where the effects of rotation are taken into account. Finally, we shortly describe next planned upgrades.

Energetics and dynamics of simple impulsive solar flares

NASA Technical Reports Server (NTRS)

Starr, R.; Heindl, W. A.; Crannell, C. J.; Thomas, R. J.; Batchelor, D. A.; Magun, A.

1987-01-01

Flare energetics and dynamics were studied using observations of simple impulsive spike bursts. A large, homogeneous set of events was selected to enable the most definite tests possible of competing flare models, in the absence of spatially resolved observations. The emission mechanisms and specific flare models that were considered in this investigation are described, and the derivations of the parameters that were tested are presented. Results of the correlation analysis between soft and hard X-ray energetics are also presented. The ion conduction front model and tests of that model with the well-observed spike bursts are described. Finally, conclusions drawn from this investigation and suggestions for future studies are discussed.

Brazilian Portuguese version of the Anger Rumination Scale (ARS-Brazil).

PubMed

Sperotto, Daniela; Manfro, Arthur Gus; Axelrud, Luiza Kvitko; Manfro, Pedro Henrique; Salum, Giovanni Abrahão; DeSousa, Diogo Araújo

2018-03-01

Objective To describe the cross-cultural adaptation of the Anger Rumination Scale (ARS) for use in Brazil. Methods The cross-cultural adaptation followed a four-step process, based on specialized literature: 1) investigation of conceptual and item equivalence; 2) translation and back-translation; 3) pretest; and 4) investigation of operational equivalence. Results A final Brazilian version of the instrument (ARS-Brazil) was defined and is presented. Pretest results revealed that the instrument was generally well understood by adults as well as indicated a few modifications that were included in the final version presented here. Conclusion The Brazilian Portuguese version of the ARS seems to be very similar to the original ARS in terms of conceptual and item equivalence, semantics, and operational equivalence, suggesting that future cross-cultural studies may benefit from this early version. As a result, a new instrument is now available for the assessment of rumination symptoms of anger and irritability for adults in community, clinical, and research settings.

The implications of free 3D scanning in the conservation state assessment of old wood painted icon

NASA Astrophysics Data System (ADS)

Munteanu, Marius; Sandu, Ion

2016-06-01

The present paper presents the conservation state and the making of a 3D model of a XVIII-th century orthodox icon on wood support, using free available software and cloud computing. In order to create the 3D model of the painting layer of the icon a number of 70 pictures were taken using a Nikon DSLR D3300, 24.2 MP in setup with a Hama Star 75 photo tripod, in loops 360° around the painting, at three different angles. The pictures were processed with Autodesk I23D Catch, which automatically finds and matches common features among all of the uploaded photographs in order to create the 3D scene, using the power and speed of cloud computing. The obtained 3D model was afterwards analyzed and processed in order to obtain a final version, which can now be use to better identify, to map and to prioritize the future conservation processes and finally can be shared online as an animation.

The Future of Pharmaceutical Manufacturing Sciences

PubMed Central

2015-01-01

The entire pharmaceutical sector is in an urgent need of both innovative technological solutions and fundamental scientific work, enabling the production of highly engineered drug products. Commercial‐scale manufacturing of complex drug delivery systems (DDSs) using the existing technologies is challenging. This review covers important elements of manufacturing sciences, beginning with risk management strategies and design of experiments (DoE) techniques. Experimental techniques should, where possible, be supported by computational approaches. With that regard, state‐of‐art mechanistic process modeling techniques are described in detail. Implementation of materials science tools paves the way to molecular‐based processing of future DDSs. A snapshot of some of the existing tools is presented. Additionally, general engineering principles are discussed covering process measurement and process control solutions. Last part of the review addresses future manufacturing solutions, covering continuous processing and, specifically, hot‐melt processing and printing‐based technologies. Finally, challenges related to implementing these technologies as a part of future health care systems are discussed. © 2015 The Authors. Journal of Pharmaceutical Sciences published by Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci 104:3612–3638, 2015 PMID:26280993

The Future of Pharmaceutical Manufacturing Sciences.

PubMed

Rantanen, Jukka; Khinast, Johannes

2015-11-01

The entire pharmaceutical sector is in an urgent need of both innovative technological solutions and fundamental scientific work, enabling the production of highly engineered drug products. Commercial-scale manufacturing of complex drug delivery systems (DDSs) using the existing technologies is challenging. This review covers important elements of manufacturing sciences, beginning with risk management strategies and design of experiments (DoE) techniques. Experimental techniques should, where possible, be supported by computational approaches. With that regard, state-of-art mechanistic process modeling techniques are described in detail. Implementation of materials science tools paves the way to molecular-based processing of future DDSs. A snapshot of some of the existing tools is presented. Additionally, general engineering principles are discussed covering process measurement and process control solutions. Last part of the review addresses future manufacturing solutions, covering continuous processing and, specifically, hot-melt processing and printing-based technologies. Finally, challenges related to implementing these technologies as a part of future health care systems are discussed. © 2015 The Authors. Journal of Pharmaceutical Sciences published by Wiley Periodicals, Inc. and the American Pharmacists Association.

Impacts of climate change on the future of biodiversity.

PubMed

Bellard, Céline; Bertelsmeier, Cleo; Leadley, Paul; Thuiller, Wilfried; Courchamp, Franck

2012-04-01

Many studies in recent years have investigated the effects of climate change on the future of biodiversity. In this review, we first examine the different possible effects of climate change that can operate at individual, population, species, community, ecosystem and biome scales, notably showing that species can respond to climate change challenges by shifting their climatic niche along three non-exclusive axes: time (e.g. phenology), space (e.g. range) and self (e.g. physiology). Then, we present the principal specificities and caveats of the most common approaches used to estimate future biodiversity at global and sub-continental scales and we synthesise their results. Finally, we highlight several challenges for future research both in theoretical and applied realms. Overall, our review shows that current estimates are very variable, depending on the method, taxonomic group, biodiversity loss metrics, spatial scales and time periods considered. Yet, the majority of models indicate alarming consequences for biodiversity, with the worst-case scenarios leading to extinction rates that would qualify as the sixth mass extinction in the history of the earth. © 2012 Blackwell Publishing Ltd/CNRS.

Impacts of climate change on the future of biodiversity

PubMed Central

Leadley, Paul; Thuiller, Wilfried; Courchamp, Franck

2013-01-01

Many studies in recent years have investigated the effects of climate change on the future of biodiversity. In this review, we first examine the different possible effects of climate change that can operate at individual, population, species, community, ecosystem and biome scales, notably showing that species can respond to climate change challenges by shifting their climatic niche along three non-exclusive axes: time (e.g., phenology), space (e.g., range) and self (e.g., physiology). Then, we present the principal specificities and caveats of the most common approaches used to estimate future biodiversity at global and sub-continental scales and we synthesize their results. Finally, we highlight several challenges for future research both in theoretical and applied realms. Overall, our review shows that current estimates are very variable, depending on the method, taxonomic group, biodiversity loss metrics, spatial scales and time periods considered. Yet, the majority of models indicate alarming consequences for biodiversity, with the worst-case scenarios leading to extinction rates that would qualify as the sixth mass extinction in the history of the earth. PMID:22257223

Past, present and future of the climate and human health commission.

PubMed

Fdez-Arroyabe, Pablo; Robau, Daysarih Tápanes

2017-09-01

The following paper presents the history of the Climate and Human Health Commission at the International Society of Biometeorology after more than one decade since its creation. A brief history of the origins of the human biometeorology is revealed through some of the main research topics and publications of the founders of the society in this field. Secondly, it is presented as a brief review of the activities of the commission in the last 10 years, based on the reports that have periodically been submitted by members of the commission to the Bulletin of the society. A summary of the topics of interest on human biometeorology and the most frequent research topics are also described. Thirdly, the need of adapting human biometeorology contents, methods and techniques to a changing world is articulated according to some of the new environmental threats in the XXI century. Finally, a list of future actions and research lines collected through a form from members of the commission is presented. The paper concludes with the existence of great challenge for human biometeorology in order to transform biometeorological knowledge into specific services to improve the wellbeing of human beings.

Future of the Middle Rio Grande

Treesearch

Barbara A. Coe

1999-01-01

Because decisions made today about the Middle Rio Grande will influence future conditions, symposium participants - the stakeholders - collaborated in a final session to plan improvements for the watershed and river corridor. The result included several action plans focusing on desired future conditions and actions to achieve them.

76 FR 65999 - Effective Date for Swap Regulation

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-25

... COMMODITY FUTURES TRADING COMMISSION 17 CFR Chapter 1 Effective Date for Swap Regulation AGENCY: Commodity Futures Trading Commission. ACTION: Notice of proposed amendment. SUMMARY: On July 14, 2011, the Commodity Futures Trading Commission (``CFTC'' or the ``Commission'') issued a final order (``July 14 Order...

Citation analysis of the prognosis of Haux et al. for the year 2013.

PubMed

Stausberg, Jürgen

2014-07-01

In 2002, Haux, Ammenwerth, Herzog, and Knaup published a prognosis about health care in the information society. In contrast to other prognoses, they underpinned their 30 theses with 71 quantitative statements that could be easily checked. A citation analysis was performed to assess the perception of this work in the medical informatics community. The ISI Web of Science was used for the citation search. From 55 hits, 38 articles were finally included in the metadata analysis, 33 articles in the qualitative analysis. The most prominent statement citing the paper of Haux et al. was identified in each article, divided into statements about the present and those about the future. Each statement was tagged with one keyword out of a convenient list. One article provided a statement about the present and the future. Most of the references were published in English as journal articles between 2006 and 2009. The majority of the first authors were from Europe. Twenty-two articles offered a statement about the present, 12 about the future. There was a shift from the present emphasis on electronic medical records and information and communication technologies to challenges in the future because of an aging population and the advent of personalized medicine. The citing papers seemed to be representative of medical informatics in terms of journals and the authors' countries of origin. The statements relating the citing literature with the paper of Haux et al. corresponded well with current notions about medical informatics. However, there was no debate about the concrete theses and prognoses offered in the cited paper. Therefore, the medical informatics community needs to rethink its own citation strategy.

Factors influencing medical students' choice of future specialization in medical sciences: a cross-sectional questionnaire survey from medical schools in china, malaysia and regions of South asian association for regional cooperation.

PubMed

Kumar, Arun; Mitra, Kasturi; Nagarajan, Sangeetha; Poudel, Bibek

2014-03-01

In future, increase in the number of healthcare professionals is dependent on the career interest among present undergraduate medical students. Based on their interest to pursue their specialty, the availability of medical doctors in each specialty could be done. This study was to find out future career interest and factors that influence undergraduate medical students to choose their future specialization. The study was carried out among first-year medical students from five countries. The students were asked to complete an 8-item questionnaire. Two thousand one hundred fifty three participants were enrolled in the study. Data were analyzed in Microsoft-Excel and Statistical Package for the Social Sciences. Of the 2153 participants, only 1470 responded. Among the 1470 participants, 169 participants were excluded due to the ambiguity in responses, finally making it to 1301participants. Among them, Anatomy (49.3%) followed by Biochemistry (26.7%) and Physiology (24%) were the most preferred subjects. Anatomy was the most preferred basic science subject among the other subjects and the students were interested to pursuing surgery in future. Furthermore, the most preferred future specialties were surgery, internal medicine and pediatrics with gender variations; males preferring surgery and females in obstetrics and gynecology.

Projecting Drivers of Human Vulnerability under the Shared Socioeconomic Pathways.

PubMed

Rohat, Guillaume

2018-03-19

The Shared Socioeconomic Pathways (SSPs) are the new set of alternative futures of societal development that inform global and regional climate change research. They have the potential to foster the integration of socioeconomic scenarios within assessments of future climate-related health impacts. To date, such assessments have primarily superimposed climate scenarios on current socioeconomic conditions only. Until now, the few assessments of future health risks that employed the SSPs have focused on future human exposure-i.e., mainly future population patterns-, neglecting future human vulnerability. This paper first explores the research gaps-mainly linked to the paucity of available projections-that explain such a lack of consideration of human vulnerability under the SSPs. It then highlights the need for projections of socioeconomic variables covering the wide range of determinants of human vulnerability, available at relevant spatial and temporal scales, and accounting for local specificities through sectoral and regional extended versions of the global SSPs. Finally, this paper presents two innovative methods of obtaining and computing such socioeconomic projections under the SSPs-namely the scenario matching approach and an approach based on experts' elicitation and correlation analyses-and applies them to the case of Europe. They offer a variety of possibilities for practical application, producing projections at sub-national level of various drivers of human vulnerability such as demographic and social characteristics, urbanization, state of the environment, infrastructure, health status, and living arrangements. Both the innovative approaches presented in this paper and existing methods-such as the spatial disaggregation of existing projections and the use of sectoral models-show great potential to enhance the availability of relevant projections of determinants of human vulnerability. Assessments of future climate-related health impacts should thus rely on these methods to account for future human vulnerability-under varying levels of socioeconomic development-and to explore its influence on future health risks under different degrees of climate change.

Projecting Drivers of Human Vulnerability under the Shared Socioeconomic Pathways

PubMed Central

2018-01-01

The Shared Socioeconomic Pathways (SSPs) are the new set of alternative futures of societal development that inform global and regional climate change research. They have the potential to foster the integration of socioeconomic scenarios within assessments of future climate-related health impacts. To date, such assessments have primarily superimposed climate scenarios on current socioeconomic conditions only. Until now, the few assessments of future health risks that employed the SSPs have focused on future human exposure—i.e., mainly future population patterns—, neglecting future human vulnerability. This paper first explores the research gaps—mainly linked to the paucity of available projections—that explain such a lack of consideration of human vulnerability under the SSPs. It then highlights the need for projections of socioeconomic variables covering the wide range of determinants of human vulnerability, available at relevant spatial and temporal scales, and accounting for local specificities through sectoral and regional extended versions of the global SSPs. Finally, this paper presents two innovative methods of obtaining and computing such socioeconomic projections under the SSPs—namely the scenario matching approach and an approach based on experts’ elicitation and correlation analyses—and applies them to the case of Europe. They offer a variety of possibilities for practical application, producing projections at sub-national level of various drivers of human vulnerability such as demographic and social characteristics, urbanization, state of the environment, infrastructure, health status, and living arrangements. Both the innovative approaches presented in this paper and existing methods—such as the spatial disaggregation of existing projections and the use of sectoral models—show great potential to enhance the availability of relevant projections of determinants of human vulnerability. Assessments of future climate-related health impacts should thus rely on these methods to account for future human vulnerability—under varying levels of socioeconomic development—and to explore its influence on future health risks under different degrees of climate change. PMID:29562727

Beam dynamics issues in linear colliders

DOE Office of Scientific and Technical Information (OSTI.GOV)

Seeman, J.T.

1989-06-01

The primary goal of present and future linear colliders is to maximize the integrated luminosity for the experimental program. Beam dynamics plays a central role in the maximization of integrated luminosity. It is the major issue in the production of small beam sizes and low experimental backgrounds and is also an important factor in the production of particle numbers, in the acceleration process, and in the number of bunches. The beam dynamics effects on bunches which are extracted from the damping rings, accelerated in the linac, collimated, momentum analyzed, and finally delivered to the final focus are reviewed. The effectsmore » of bunch compression, transverse and longitudinal wakefields, BNS damping, energy definition, dispersion, emittance, bunch aspect ratio, feedback, and stability are all important. 11 refs., 1 tab.« less

Additional Technologies and Investigations for Provision of Future Aeronautical Communications

NASA Technical Reports Server (NTRS)

Gilbert, Tricia; Jin, Jenny; Berger, Jason; Henriksen, Steve

2008-01-01

The following NASA Contractor Report documents the in-depth studies on select technologies that could support long-term aeronautical mobile communications operating concepts. This work was performed during the third and final phase of NASA s Technology Assessment for the Federal Aviation Administration (FAA)/EUROCONTROL Future Communications Study (FCS) under a multiyear NASA contract. It includes the associated findings of ITT Corporation and NASA Glenn Research Center to the FAA as of the end of May 2007. The activities documented in this report focus on three final technology candidates identified by the United States, and were completed before sufficient information about two additional technology candidates proposed by EUROCONTROL was made available. A separate report to be published by NASA/CR-2008-215144, entitled Final Report on Technology Investigations for Provision of Future Aeronautical Communications will include an assessment of all five final candidate technologies considered by the U.S. agencies (FAA and NASA) and EUROCONTROL. It will also provide an overview of the entire technology assessment process, including final recommendations. All three phases of this work were performed in compliance with the Terms of Reference for the Action Plan number 17 (AP-17) cooperative research agreement among EUROCONTROL, FAA, and NASA along with the general guidance of the FAA and EUROCONTROL available throughout this study.

Smart manufacturing systems for Industry 4.0: Conceptual framework, scenarios, and future perspectives

NASA Astrophysics Data System (ADS)

Zheng, Pai; wang, Honghui; Sang, Zhiqian; Zhong, Ray Y.; Liu, Yongkui; Liu, Chao; Mubarok, Khamdi; Yu, Shiqiang; Xu, Xun

2018-06-01

Information and communication technology is undergoing rapid development, and many disruptive technologies, such as cloud computing, Internet of Things, big data, and artificial intelligence, have emerged. These technologies are permeating the manufacturing industry and enable the fusion of physical and virtual worlds through cyber-physical systems (CPS), which mark the advent of the fourth stage of industrial production (i.e., Industry 4.0). The widespread application of CPS in manufacturing environments renders manufacturing systems increasingly smart. To advance research on the implementation of Industry 4.0, this study examines smart manufacturing systems for Industry 4.0. First, a conceptual framework of smart manufacturing systems for Industry 4.0 is presented. Second, demonstrative scenarios that pertain to smart design, smart machining, smart control, smart monitoring, and smart scheduling, are presented. Key technologies and their possible applications to Industry 4.0 smart manufacturing systems are reviewed based on these demonstrative scenarios. Finally, challenges and future perspectives are identified and discussed.

Applications of the laser

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goldman, L.

For those not familiar with lasers, a review of lasers and some remarks on the fascinating new developments in such systems that do affect applications now and in the future are presented. Wave guides to transmit lasers to make them more flexible, the important aspects of measurements, chemistry, bits of botany, and holography are given. The vast expanse of communications, especially through the development of the new and important hybrid discipline of electrooptics is reviewed. The military and law and order programs show their applications; all initiate the study of actual applications. Then follow metalworking, construction, pollution, and a numbermore » of miscellaneous techniques. A critical review of safety programs so necessary for the proper development of laser technology is presented. Then follows the story of the applications in biology, medicine, dentistry, photography, art, and music. Many of the applications cross to other fields. To stimulate the youth to be interested in science, there are brief remarks about the social conscience in laser and, finally, the dreams of the future.« less

The factor structure of posttraumatic stress disorder: a literature update, critique of methodology, and agenda for future research.

PubMed

Elhai, Jon D; Palmieri, Patrick A

2011-08-01

We present an update of recent literature (since 2007) exploring the factor structure of posttraumatic stress disorder (PTSD) symptom measures. Research supporting a four-factor emotional numbing model and a four-factor dysphoria model is presented, with these models fitting better than all other models examined. Variables accounting for factor structure differences are reviewed, including PTSD query instructions, type of PTSD measure, extent of trauma exposure, ethnicity, and timing of administration. Methodological and statistical limitations with recent studies are presented. Finally, a research agenda and recommendations are offered to push this research area forward, including suggestions to validate PTSD’s factors against external measures of psychopathology, test moderators of factor structure, and examine heterogeneity of symptom presentations based on factor structure examination.

Design and implementation of a biomimetic turtle hydrofoil for an autonomous underwater vehicle.

PubMed

Font, Davinia; Tresanchez, Marcel; Siegentahler, Cedric; Pallejà, Tomàs; Teixidó, Mercè; Pradalier, Cedric; Palacin, Jordi

2011-01-01

This paper presents the design and implementation of a turtle hydrofoil for an Autonomous Underwater Vehicle (AUV). The final design of the AUV must have navigation performance like a turtle, which has also been the biomimetic inspiration for the design of the hydrofoil and propulsion system. The hydrofoil design is based on a National Advisory Committee for Aeronautics (NACA) 0014 hydrodynamic profile. During the design stage, four different propulsion systems were compared in terms of propulsion path, compactness, sealing and required power. The final implementation is based on a ball-and-socket mechanism because it is very compact and provides three degrees of freedom (DoF) to the hydrofoil with very few restrictions on the propulsion path. The propulsion obtained with the final implementation of the hydrofoil has been empirically evaluated in a water channel comparing different motion strategies. The results obtained have confirmed that the proposed turtle hydrofoil controlled with a mechanism with three DoF generates can be used in the future implementation of the planned AUV.

The Virtual Solar-Terrestrial Observatory; access to and use of diverse solar and solar- terrestrial data.

NASA Astrophysics Data System (ADS)

Fox, P.; McGuinness, D.; Cinquini, L.; West, P.; Garcia, J.; Zednik, S.; Benedict, J.

2008-05-01

This presentation will demonstrate how users and other data providers can utilize the Virtual Solar-Terrestrial Observatory (VSTO) to find, access and use diverse data holdings from the disciplines of solar, solar-terrestrial and space physics. VSTO provides a web portal, web services and a native applications programming interface for various levels of users. Since these access methods are based on semantic web technologies and refer to the VSTO ontology, users also have the option of taking advantage of value added services when accessing and using the data. We present example of both conventional use of VSTO as well as the advanced semantics use. Finally, we present our future directions for VSTO and semantic data frameworks in general.

The Virtual Solar-Terrestrial Observatory; access to and use of diverse solar and solar-terrestrial data

NASA Astrophysics Data System (ADS)

Fox, P.

2007-05-01

This presentation will demonstrate how users and other data providers can utilize the Virtual Solar-Terrestrial Observatory (VSTO) to find, access and use diverse data holdings from the disciplines of solar, solar-terrestrial and space physics. VSTO provides a web portal, web services and a native applications programming interface for various levels of users. Since these access methods are based on semantic web technologies and refer to the VSTO ontology, users also have the option of taking advantage of value added services when accessing and using the data. We present example of both conventional use of VSTO as well as the advanced semantics use. Finally, we present our future directions for VSTO and semantic data frameworks in general.

Trends in biotechnological production of fuel ethanol from different feedstocks.

PubMed

Sánchez, Oscar J; Cardona, Carlos A

2008-09-01

Present work deals with the biotechnological production of fuel ethanol from different raw materials. The different technologies for producing fuel ethanol from sucrose-containing feedstocks (mainly sugar cane), starchy materials and lignocellulosic biomass are described along with the major research trends for improving them. The complexity of the biomass processing is recognized through the analysis of the different stages involved in the conversion of lignocellulosic complex into fermentable sugars. The features of fermentation processes for the three groups of studied feedstocks are discussed. Comparative indexes for the three major types of feedstocks for fuel ethanol production are presented. Finally, some concluding considerations on current research and future tendencies in the production of fuel ethanol regarding the pretreatment and biological conversion of the feedstocks are presented.

Energy study of rail passenger transportation. Volume 4. Efficiency improvements and industry future. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Henderson, C.; Wilhelm, J.P.

1979-08-01

Measures that offer promise of efficiency improvements or economy in energy usage in rail passenger transportation are identified and described; the future of rail passenger transportation in the US is discussed; and possible future roles of Federal agencies are discussed.

76 FR 44464 - Process for Review of Swaps for Mandatory Clearing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-26

... COMMODITY FUTURES TRADING COMMISSION 17 CFR Parts 39 and 140 RIN 3038-AD00 Process for Review of Swaps for Mandatory Clearing AGENCY: Commodity Futures Trading Commission. ACTION: Final rule. SUMMARY: The Commodity Futures Trading Commission (Commission or CFTC) is adopting regulations to implement...

Base excision repair in Archaea: back to the future in DNA repair.

PubMed

Grasso, Stefano; Tell, Gianluca

2014-09-01

Together with Bacteria and Eukarya, Archaea represents one of the three domain of life. In contrast with the morphological difference existing between Archaea and Eukarya, these two domains are closely related. Phylogenetic analyses confirm this evolutionary relationship showing that most of the proteins involved in DNA transcription and replication are highly conserved. On the contrary, information is scanty about DNA repair pathways and their mechanisms. In the present review the most important proteins involved in base excision repair, namely glycosylases, AP lyases, AP endonucleases, polymerases, sliding clamps, flap endonucleases, and ligases, will be discussed and compared with bacterial and eukaryotic ones. Finally, possible applications and future perspectives derived from studies on Archaea and their repair pathways, will be taken into account. Copyright © 2014 Elsevier B.V. All rights reserved.

Thirty years of Batten disease research: present status and future goals.

PubMed

Rider, J A; Rider, D L

1999-04-01

From a meager beginning in 1968, when Batten disease or neuronal ceroid lipofuscinosis was practically unheard of, tremendous advances have been made. It is now recognized worldwide as the most common neurodegenerative disease in children and young adults. It is recognized as a genetic disease. The infantile form has been localized to chromosome 1 p32 and the juvenile form, to 16p12.1; the gene for the late infantile is on chromosome 11p15 and for a variant form of the late infantile, the gene lies on chromosome 15q21-23. Finally, the molecular basis of the late infantile form is probably a pepstatin-insensitive lysomal peptidase. The future is to identify carriers, prevent the disease, and develop treatment by gene and enzyme replacement. Copyright 1999 Academic Press.

Optical distribution of local oscillators in future telecommunication satellite payloads

NASA Astrophysics Data System (ADS)

Benazet, Benoît; Sotom, Michel; Maignan, Michel; Berthon, Jacques

2017-11-01

The distribution of high spectral purity reference signals over optical fibre in future telecommunication satellite payloads is presented. Several types of applications are considered, including the distribution of a reference frequency at 10 MHz (Ultra-Stable Reference Oscillator) as well as the distribution of a radiofrequency oscillator around 800 MHz (Master Local Oscillator). The results of both experimental and theoretical studies are reported. In order to meet phase noise requirements for the USRO distribution, the use of an optimised receiver circuit based on an optically synchronised oscillator is investigated. Finally, the optical distribution of microwave local oscillators at frequencies exceeding 20 GHz is described. Such a scheme paves the way to more advanced sub-systems involving optical frequency-mixing and optical transmission of microwave signals, with applications to multiple-beam active antennas.

Testing and reference model analysis of FTTH system

NASA Astrophysics Data System (ADS)

Feng, Xiancheng; Cui, Wanlong; Chen, Ying

2009-08-01

With rapid development of Internet and broadband access network, the technologies of xDSL, FTTx+LAN , WLAN have more applications, new network service emerges in endless stream, especially the increase of network game, meeting TV, video on demand, etc. FTTH supports all present and future service with enormous bandwidth, including traditional telecommunication service, traditional data service and traditional TV service, and the future digital TV and VOD. With huge bandwidth of FTTH, it wins the final solution of broadband network, becomes the final goal of development of optical access network.. Fiber to the Home (FTTH) will be the goal of telecommunications cable broadband access. In accordance with the development trend of telecommunication services, to enhance the capacity of integrated access network, to achieve triple-play (voice, data, image), based on the existing optical Fiber to the curb (FTTC), Fiber To The Zone (FTTZ), Fiber to the Building (FTTB) user optical cable network, the optical fiber can extend to the FTTH system of end-user by using EPON technology. The article first introduced the basic components of FTTH system; and then explain the reference model and reference point for testing of the FTTH system; Finally, by testing connection diagram, the testing process, expected results, primarily analyze SNI Interface Testing, PON interface testing, Ethernet performance testing, UNI interface testing, Ethernet functional testing, PON functional testing, equipment functional testing, telephone functional testing, operational support capability testing and so on testing of FTTH system. ...

Photocathode Optimization for a Dynamic Transmission Electron Microscope: Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ellis, P; Flom, Z; Heinselman, K

2011-08-04

The Dynamic Transmission Electron Microscope (DTEM) team at Harvey Mudd College has been sponsored by LLNL to design and build a test setup for optimizing the performance of the DTEM's electron source. Unlike a traditional TEM, the DTEM achieves much faster exposure times by using photoemission from a photocathode to produce electrons for imaging. The DTEM team's work is motivated by the need to improve the coherence and current density of the electron cloud produced by the electron gun in order to increase the image resolution and contrast achievable by DTEM. The photoemission test setup is nearly complete and themore » team will soon complete baseline tests of electron gun performance. The photoemission laser and high voltage power supply have been repaired; the optics path for relaying the laser to the photocathode has been finalized, assembled, and aligned; the internal setup of the vacuum chamber has been finalized and mostly implemented; and system control, synchronization, and data acquisition has been implemented in LabVIEW. Immediate future work includes determining a consistent alignment procedure to place the laser waist on the photocathode, and taking baseline performance measurements of the tantalum photocathode. Future research will examine the performance of the electron gun as a function of the photoemission laser profile, the photocathode material, and the geometry and voltages of the accelerating and focusing components in the electron gun. This report presents the team's progress and outlines the work that remains.« less

78 FR 64173 - Swap Dealers and Major Swap Participants; Clerical or Ministerial Employees

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-28

... COMMODITY FUTURES TRADING COMMISSION 17 CFR Part 23 RIN 3038-AE00 Swap Dealers and Major Swap Participants; Clerical or Ministerial Employees AGENCY: Commodity Futures Trading Commission. ACTION: Final rule. SUMMARY: The Commodity Futures Trading Commission is adopting an amendment to its regulations to...

Future landfill emissions and the effect of final cover installation--a case study.

PubMed

Laner, David; Fellner, Johann; Brunner, Paul H

2011-07-01

Municipal solid waste (MSW) landfills are potential long-term sources of emissions. Hence, they need to be managed after closure until they do not pose a threat to humans or the environment. The case study on the Breitenau MSW landfill was performed to evaluate future emission levels for this site and to illustrate the effect of final cover installation with respect to long-term environmental risks. The methodology was based on a comprehensive assessment of the state of the landfill and included analysis of monitoring data, investigations of landfilled waste, and an evaluation of containment systems. A model to estimate future emission levels was established and site-specific predictions of leachate emissions were presented based on scenario analysis. The results are used to evaluate the future pollution potential of the landfill and to compare different aftercare concepts in view of long-term emissions. As some leachable substances became available for water flow during cover construction due to a change in the water flow pattern of the waste, a substantial increase in leachate concentrations could be observed at the site (e.g. concentrations of chloride increased from 200 to 800 mg/l and of ammonia-nitrogen from 140 to about 500 mg/l). A period of intensive flushing before the final cover installation could have reduced the amount of leachable substances within the landfill body and rapidly decreased the leachate concentrations to 11 mg Cl/l and 79 mg NH(4)-N/l within 50 years. Contrarily, the minimization of water infiltration is associated with leachate concentrations in a high range for centuries (above 400 mg Cl/l and 200 mg NH(4)-N/l) with low concomitant annual emission loads (below 12 kg/year of Cl or 9 kg/year of NH(4)-N, respectively). However, an expected gradual decrease of barrier efficiency over time would be associated with higher emission loads of 50 kg of chloride and 30 kg of ammonia-nitrogen at the maximum, but a faster decrease of leachate concentration levels. Copyright © 2011 Elsevier Ltd. All rights reserved.

Stochastic volatility of the futures prices of emission allowances: A Bayesian approach

NASA Astrophysics Data System (ADS)

Kim, Jungmu; Park, Yuen Jung; Ryu, Doojin

2017-01-01

Understanding the stochastic nature of the spot volatility of emission allowances is crucial for risk management in emissions markets. In this study, by adopting a stochastic volatility model with or without jumps to represent the dynamics of European Union Allowances (EUA) futures prices, we estimate the daily volatilities and model parameters by using the Markov Chain Monte Carlo method for stochastic volatility (SV), stochastic volatility with return jumps (SVJ) and stochastic volatility with correlated jumps (SVCJ) models. Our empirical results reveal three important features of emissions markets. First, the data presented herein suggest that EUA futures prices exhibit significant stochastic volatility. Second, the leverage effect is noticeable regardless of whether or not jumps are included. Third, the inclusion of jumps has a significant impact on the estimation of the volatility dynamics. Finally, the market becomes very volatile and large jumps occur at the beginning of a new phase. These findings are important for policy makers and regulators.

Sea-level rise caused by climate change and its implications for society

PubMed Central

MIMURA, Nobuo

2013-01-01

Sea-level rise is a major effect of climate change. It has drawn international attention, because higher sea levels in the future would cause serious impacts in various parts of the world. There are questions associated with sea-level rise which science needs to answer. To what extent did climate change contribute to sea-level rise in the past? How much will global mean sea level increase in the future? How serious are the impacts of the anticipated sea-level rise likely to be, and can human society respond to them? This paper aims to answer these questions through a comprehensive review of the relevant literature. First, the present status of observed sea-level rise, analyses of its causes, and future projections are summarized. Then the impacts are examined along with other consequences of climate change, from both global and Japanese perspectives. Finally, responses to adverse impacts will be discussed in order to clarify the implications of the sea-level rise issue for human society. PMID:23883609

Black and white and read all over: the past, present and future of giant panda genetics.

PubMed

Wei, Fuwen; Hu, Yibo; Zhu, Lifeng; Bruford, Michael W; Zhan, Xiangjiang; Zhang, Lei

2012-12-01

Few species attract much more attention from the public and scientists than the giant panda (Ailuropoda melanoleuca), a popular, enigmatic but highly endangered species. The application of molecular genetics to its biology and conservation has facilitated surprising insights into the biology of giant pandas as well as the effectiveness of conservation efforts during the past decades. Here, we review the history of genetic advances in this species, from phylogeny, demographical history, genetic variation, population structure, noninvasive population census and adaptive evolution to reveal to what extent the current status of the giant panda is a reflection of its evolutionary legacy, as opposed to the influence of anthropogenic factors that have negatively impacted this species. In addition, we summarize the conservation implications of these genetic findings applied for the management of this high-profile species. Finally, on the basis of these advances and predictable future changes in genetic technology, we discuss future research directions that seem promising for giant panda biology and conservation. © 2012 Blackwell Publishing Ltd.

Self-handicapping, excuse making, and counterfactual thinking: consequences for self-esteem and future motivation.

PubMed

McCrea, Sean M

2008-08-01

Researchers interested in counterfactual thinking have often found that upward counterfactual thoughts lead to increased motivation to improve in the future, although at the cost of increased negative affect. The present studies suggest that because upward counterfactual thoughts indicate reasons for a poor performance, they can also serve as excuses. In this case, upward counterfactual thoughts should result in more positive self-esteem and reduced future motivation. Five studies demonstrated these effects in the context of self-handicapping. First, upward counterfactual thinking was increased in the presence of a self-handicap. Second, upward counterfactual thoughts indicating the presence of a self-handicap protected self-esteem following failure. Finally, upward counterfactual thoughts that protect self-esteem reduced preparation for a subsequent performance as well as performance itself. These findings suggest that the consequences of upward counterfactuals for affect and motivation are moderated by the goals of the individual as well as the content of the thoughts. (c) 2008 APA, all rights reserved

Testing sterile neutrino extensions of the Standard Model at future lepton colliders

NASA Astrophysics Data System (ADS)

Antusch, Stefan; Fischer, Oliver

2015-05-01

Extending the Standard Model (SM) with sterile ("right-handed") neutrinos is one of the best motivated ways to account for the observed neutrino masses. We discuss the expected sensitivity of future lepton collider experiments for probing such extensions. An interesting testable scenario is given by "symmetry protected seesaw models", which theoretically allow for sterile neutrino masses around the electroweak scale with up to order one mixings with the light (SM) neutrinos. In addition to indirect tests, e.g. via electroweak precision observables, sterile neutrinos with masses around the electroweak scale can also be probed by direct searches, e.g. via sterile neutrino decays at the Z pole, deviations from the SM cross section for four lepton final states at and beyond the WW threshold and via Higgs boson decays. We study the present bounds on sterile neutrino properties from LEP and LHC as well as the expected sensitivities of possible future lepton colliders such as ILC, CEPC and FCC-ee (TLEP).

Age and Impulsive Behavior in Drug Addiction: A Review of Past Research and Future Directions

PubMed Central

Argyriou, Evangelia; Um, Miji; Carron, Clair; Cyders, Melissa A.

2018-01-01

Impulsive behavior is implicated in the initiation, maintenance, and relapse of drug-seeking behaviors involved in drug addiction. Research shows that changes in impulsive behavior across the lifespan contribute to drug use and addiction. The goal of this review is to examine existing research on the relationship between impulsive behavior and drug use across the lifespan and to recommend directions for future research. Three domains of impulsive behavior are explored in this review: impulsive behavior-related personality traits, delay discounting, and prepotent response inhibition. First, we present previous research on these three domains of impulsive behavior and drug use across developmental stages. Then, we discuss how changes in impulsive behavior across the lifespan are implicated in the progression of drug use and addiction. Finally, we discuss the relatively limited attention given to middle-to-older adults in the current literature, consider the validity of the measures used to assess impulsive behavior in middle-to-older adulthood, and suggest recommendations for future research. PMID:28778737

NAIMA as a solution for future GMO diagnostics challenges.

PubMed

Dobnik, David; Morisset, Dany; Gruden, Kristina

2010-03-01

In the field of genetically modified organism (GMO) diagnostics, real-time PCR has been the method of choice for target detection and quantification in most laboratories. Despite its numerous advantages, however, the lack of a true multiplexing option may render real-time PCR less practical in the face of future GMO detection challenges such as the multiplicity and increasing complexity of new transgenic events, as well as the repeated occurrence of unauthorized GMOs on the market. In this context, we recently reported the development of a novel multiplex quantitative DNA-based target amplification method, named NASBA implemented microarray analysis (NAIMA), which is suitable for sensitive, specific and quantitative detection of GMOs on a microarray. In this article, the performance of NAIMA is compared with that of real-time PCR, the focus being their performances in view of the upcoming challenge to detect/quantify an increasing number of possible GMOs at a sustainable cost and affordable staff effort. Finally, we present our conclusions concerning the applicability of NAIMA for future use in GMO diagnostics.

Aerothermodynamic testing requirements for future space transportation systems

NASA Technical Reports Server (NTRS)

Paulson, John W., Jr.; Miller, Charles G., III

1995-01-01

Aerothermodynamics, encompassing aerodynamics, aeroheating, and fluid dynamic and physical processes, is the genesis for the design and development of advanced space transportation vehicles. It provides crucial information to other disciplines involved in the development process such as structures, materials, propulsion, and avionics. Sources of aerothermodynamic information include ground-based facilities, computational fluid dynamic (CFD) and engineering computer codes, and flight experiments. Utilization of this triad is required to provide the optimum requirements while reducing undue design conservatism, risk, and cost. This paper discusses the role of ground-based facilities in the design of future space transportation system concepts. Testing methodology is addressed, including the iterative approach often required for the assessment and optimization of configurations from an aerothermodynamic perspective. The influence of vehicle shape and the transition from parametric studies for optimization to benchmark studies for final design and establishment of the flight data book is discussed. Future aerothermodynamic testing requirements including the need for new facilities are also presented.

Quantifying Direct and Indirect Impact of Future Climate on Sub-Arctic Hydrology

NASA Astrophysics Data System (ADS)

Endalamaw, A. M.; Bolton, W. R.; Young-Robertson, J. M.; Morton, D.; Hinzman, L. D.

2016-12-01

Projected future climate will have a significant impact on the hydrology of interior Alaskan sub-arctic watersheds, directly though the changes in precipitation and temperature patterns, and indirectly through the cryospheric and ecological impacts. Although the latter is the dominant factor controlling the hydrological processes in the interior Alaska sub-arctic, it is often overlooked in many climate change impact studies. In this study, we aim to quantify and compare the direct and indirect impact of the projected future climate on the hydrology of the interior Alaskan sub-arctic watersheds. The Variable Infiltration Capacity (VIC) meso-scale hydrological model will be implemented to simulate the hydrological processes, including runoff, evapotranspiration, and soil moisture dynamics in the Chena River Basin (area = 5400km2), located in the interior Alaska sub-arctic region. Permafrost and vegetation distribution will be derived from the Geophysical Institute Permafrost Lab (GIPL) model and the Lund-Potsdam-Jena Dynamic Global Model (LPJ) model, respectively. All models will be calibrated and validated using historical data. The Scenario Network for Alaskan and Arctic Planning (SNAP) 5-model average projected climate data products will be used as forcing data for each of these models. The direct impact of climate change on hydrology is estimated using surface parameterization derived from the present day permafrost and vegetation distribution, and future climate forcing from SNAP projected climate data products. Along with the projected future climate, outputs of GIPL and LPJ will be incorporated into the VIC model to estimate the indirect and overall impact of future climate on the hydrology processes in the interior Alaskan sub-arctic watersheds. Finally, we will present the potential hydrological and ecological changes by the end of the 21st century.

Perfect match? Generation Y as change agents for information communication technology implementation in healthcare.

PubMed

Yee, Kwang Chien; Miils, Erin; Airey, Caroline

2008-01-01

The current healthcare delivery model will not meet future healthcare demands. The only sustainable healthcare future is one that best leverages advances in technology to improve productivity and efficiency. Information communication technology (ICT) has, therefore, been touted as the panacea of future healthcare challenges. Many ICT projects in healthcare, however, fail to deliver on their promises to transform the healthcare system. From a technologist's perspective, this is often due to the lack of socio-technical consideration. From a socio-cultural perspective, however, there is often strong inertia to change. While the utilisation of user-centred design principles will generate a new wave of enthusiasm among technologists, this has to be matched with socio-cultural changes within the healthcare system. Generation Y healthcare workers might be the socio-cultural factor required, in combination with new technology, to transform the healthcare system. Generation Y has generated significant technology-driven changes in many other industries. The socio-cultural understanding of generation Y healthcare workers is essential to guide the design and implementation of ICT solutions for a sustainable healthcare future. This paper presents the initial analysis of our qualitative study which aims to generate in-depth conceptual insights of generation Y healthcare workers and their view of ICT in healthcare. Our results show that generation Y healthcare workers might assist future ICT implementation in healthcare. This paper, however, argues that significant changes to the current healthcare organisation will be required in order to unleash the full potential of generation Y workers and ICT implementation. Finally, this paper presents some strategies to empower generation Y workers as change agents for a sustainable future healthcare system.

Virtual Planning at Work: A Tour of NASA Future Flight Central

NASA Technical Reports Server (NTRS)

McClenahen, Jim; Dorighi, Nancy S. (Technical Monitor)

2000-01-01

FutureFlight Central will permit integration of tomorrow's technologies in a risk-free simulation of any airport, airfield, and tower cab environment. The facility provides an opportunity for airlines to mitigate passenger delays by fine tuning airport hub operations, gate management and ramp movement procedures. It also allows airport managers an opportunity to study effects of various improvements at their airports. Finally, it enables air traffic controllers to provide feedback and to become familiar with new airport operations and technologies before final installation.

Tech Prep II: Implementation Final Report.

ERIC Educational Resources Information Center

Brown, Jane A.

This document contains the final progress report on a tech prep implementation project and the Work Force Challenge 2000 Report developed during the project. The final report lists these major accomplishments: approximately 1,500 educators in grades K-12 were provided information concerning future global issues in the work force and the effects in…

Future internet architecture and cloud ecosystem: A survey

NASA Astrophysics Data System (ADS)

Wan, Man; Yin, Shiqun

2018-04-01

The Internet has gradually become a social infrastructure, the existing TCP/IP architecture faces many challenges. So future Internet architecture become hot research. This paper introduces two ways of idea about the future research of Internet structure system, probes into the future Internet architecture and the environment of cloud ecosystem. Finally, we focuses the related research, and discuss basic principles and problems of OpenStack.

Connecting Oceanography and Music

NASA Astrophysics Data System (ADS)

Beauregard, J. L.

2016-02-01

Capturing and retaining the interest of non-science majors in science classes can be difficult, no matter what type of science. At Berklee College of Music, this challenge is especially significant, as all students are music majors. In my Introductory Oceanography course, I use a final project as a way for the students to link class material with their own interests. The students may choose any format to present their projects to the class; however, many students write and perform original music. The performances of ocean-themed music have become a huge draw of the Introductory Oceanography course. In an effort to expand the reach of this music, several colleagues and I organized the first Earth Day event at Berklee, `Earthapalooza 2015.' This event included performances of music originally written for the final projects, as well as other musical performances, poetry readings, guest talks, and information booths. Although the idea of an Earth Day event is not new, this event is unique in that student performances really resonate with the student audience. Additionally, since many of these students will enter professional careers in the performance and recording industries, the potential exists for them to expose large audiences to the issues of oceanography through music. In this presentation, I will play examples of original student compositions and show video of the live student performances. I will also discuss the benefits and challenges of the final projects and the Earth Day event. Finally, I will highlight the future plans to continue ocean-themed music at Berklee.

Academic Pipeline and Futures Lab

DTIC Science & Technology

2016-02-01

AFRL-RY-WP-TR-2015-0186 ACADEMIC PIPELINE AND FUTURES LAB Brian D. Rigling Wright State University FEBRUARY 2016...DD-MM-YY) 2. REPORT TYPE 3. DATES COVERED (From - To) February 2016 Final 12 June 2009 – 30 September 2015 4. TITLE AND SUBTITLE ACADEMIC ...6 3 WSU ACADEMIC PIPELINE AND LAYERED SENSING FUTURES LAB (prepared by K

Future Think Program, San Jose City College, Spring Semester, 1974: Final Report of Evaluation.

ERIC Educational Resources Information Center

DCM Associates, San Francisco, CA.

San Jose City College's Future Think Program consists of the following courses: Language, Culture, and Change; Third World Since 1945; Marriage and Family; Ecology and Man; Science Fiction; Introduction to Literature: Science Fiction; Introduction to Sociology; and Sociology/Fiction of the Future. An evaluation by an independent consulting firm…

78 FR 22418 - Reassignment of Commission Staff Responsibilities and Delegations of Authority

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-16

... COMMODITY FUTURES TRADING COMMISSION 17 CFR Parts 1, 3, 5, 9, 11, 31, 40, 41, 140, 145, 170, 171... AGENCY: Commodity Futures Trading Commission. ACTION: Final rule. SUMMARY: The Commission is amending its... , Division of Clearing and Risk, Commodity Futures Trading Commission, Three Lafayette Centre, 1155 21st...

Hydrological Forecasting Practices in Brazil

NASA Astrophysics Data System (ADS)

Fan, Fernando; Paiva, Rodrigo; Collischonn, Walter; Ramos, Maria-Helena

2016-04-01

This work brings a review on current hydrological and flood forecasting practices in Brazil, including the main forecasts applications, the different kinds of techniques that are currently being employed and the institutions involved on forecasts generation. A brief overview of Brazil is provided, including aspects related to its geography, climate, hydrology and flood hazards. A general discussion about the Brazilian practices on hydrological short and medium range forecasting is presented. Detailed examples of some hydrological forecasting systems that are operational or in a research/pre-operational phase using the large scale hydrological model MGB-IPH are also presented. Finally, some suggestions are given about how the forecasting practices in Brazil can be understood nowadays, and what are the perspectives for the future.

Super-resolution from single photon emission: toward biological application

NASA Astrophysics Data System (ADS)

Moreva, E.; Traina, P.; Forneris, J.; Ditalia Tchernij, S.; Guarina, L.; Franchino, C.; Picollo, F.; Ruo Berchera, I.; Brida, G.; Degiovanni, I. P.; Carabelli, V.; Olivero, P.; Genovese, M.

2017-08-01

Properties of quantum light represent a tool for overcoming limits of classical optics. Several experiments have demonstrated this advantage ranging from quantum enhanced imaging to quantum illumination. In this work, experimental demonstration of quantum-enhanced resolution in confocal fluorescence microscopy will be presented. This is achieved by exploiting the non-classical photon statistics of fluorescence emission of single nitrogen-vacancy (NV) color centers in diamond. By developing a general model of super-resolution based on the direct sampling of the kth-order autocorrelation function of the photoluminescence signal, we show the possibility to resolve, in principle, arbitrarily close emitting centers. Finally, possible applications of NV-based fluorescent nanodiamonds in biosensing and future developments will be presented.

High-Temperature Piezoelectric Sensing

PubMed Central

Jiang, Xiaoning; Kim, Kyungrim; Zhang, Shujun; Johnson, Joseph; Salazar, Giovanni

2014-01-01

Piezoelectric sensing is of increasing interest for high-temperature applications in aerospace, automotive, power plants and material processing due to its low cost, compact sensor size and simple signal conditioning, in comparison with other high-temperature sensing techniques. This paper presented an overview of high-temperature piezoelectric sensing techniques. Firstly, different types of high-temperature piezoelectric single crystals, electrode materials, and their pros and cons are discussed. Secondly, recent work on high-temperature piezoelectric sensors including accelerometer, surface acoustic wave sensor, ultrasound transducer, acoustic emission sensor, gas sensor, and pressure sensor for temperatures up to 1,250 °C were reviewed. Finally, discussions of existing challenges and future work for high-temperature piezoelectric sensing are presented. PMID:24361928

The Past, Present and Future of Geodemographic Research in the United States and United Kingdom

PubMed Central

Singleton, Alexander D.; Spielman, Seth E.

2014-01-01

This article presents an extensive comparative review of the emergence and application of geodemographics in both the United States and United Kingdom, situating them as an extension of earlier empirically driven models of urban socio-spatial structure. The empirical and theoretical basis for this generalization technique is also considered. Findings demonstrate critical differences in both the application and development of geodemographics between the United States and United Kingdom resulting from their diverging histories, variable data economies, and availability of academic or free classifications. Finally, current methodological research is reviewed, linking this discussion prospectively to the changing spatial data economy in both the United States and United Kingdom. PMID:25484455

NASA Past, Present, and Future: The Use of Commercial Off The Shelf (COTS) Electronics in Space

NASA Technical Reports Server (NTRS)

LaBel, Kenneth A.; Guertin, Steven M.

2017-01-01

NASA has a long history of using commercial grade electronics in space. In this presentation we will provide a brief history of NASA's trends and approaches to commercial grade electronics focusing on processing and memory systems. This will include providing summary information on the space hazards to electronics as well as NASA mission trade space. We will also discuss developing recommendations for risk management approaches to Electrical, Electronic and Electromechanical (EEE) parts usage in space. Two examples will be provided focusing on a near-earth Polar-orbiting spacecraft as well as a mission to Mars. The final portion will discuss emerging trends impacting usage.

Preliminary Design and Analysis of the ARES Atmospheric Flight Vehicle Thermal Control System

NASA Technical Reports Server (NTRS)

Gasbarre, J. F.; Dillman, R. A.

2003-01-01

The Aerial Regional-scale Environmental Survey (ARES) is a proposed 2007 Mars Scout Mission that will be the first mission to deploy an atmospheric flight vehicle (AFV) on another planet. This paper will describe the preliminary design and analysis of the AFV thermal control system for its flight through the Martian atmosphere and also present other analyses broadening the scope of that design to include other phases of the ARES mission. Initial analyses are discussed and results of trade studies are presented which detail the design process for AFV thermal control. Finally, results of the most recent AFV thermal analysis are shown and the plans for future work are discussed.

Numerical aerodynamic simulation program long haul communications prototype

NASA Technical Reports Server (NTRS)

Cmaylo, Bohden K.; Foo, Lee

1987-01-01

This document is a report of the Numerical Aerodynamic Simulation (NAS) Long Haul Communications Prototype (LHCP). It describes the accomplishments of the LHCP group, presents the results from all LHCP experiments and testing activities, makes recommendations for present and future LHCP activities, and evaluates the remote workstation accesses from Langley Research Center, Lewis Research Center, and Colorado State University to Ames Research Center. The report is the final effort of the Long Haul (Wideband) Communications Prototype Plan (PT-1133-02-N00), 3 October 1985, which defined the requirements for the development, test, and operation of the LHCP network and was the plan used to evaluate the remote user bandwidth requirements for the Numerical Aerodynamic Simulation Processing System Network.

Approaches to Neural Tissue Engineering Using Scaffolds for Drug Delivery

PubMed Central

Willerth, Stephanie M.; Sakiyama-Elbert, Shelly E.

2007-01-01

This review seeks to give an overview of the current approaches to drug delivery from scaffolds for neural tissue engineering applications. The challenges presented by attempting to replicate the three types of nervous tissue (brain, spinal cord, and peripheral nerve) are summarized. Potential scaffold materials (both synthetic and natural) and target drugs are discussed with the benefits and drawbacks given. Finally, common methods of drug delivery, including degradable/diffusion-based delivery systems, affinity-based delivery systems, immobilized drug delivery systems, and electrically controlled drug delivery systems, are examined and critiqued. Based on the current body of work, suggestions for future directions of research in the field of neural tissue engineering are presented. PMID:17482308

Molecular diagnostics of neurodegenerative disorders.

PubMed

Agrawal, Megha; Biswas, Abhijit

2015-01-01

Molecular diagnostics provide a powerful method to detect and diagnose various neurological diseases such as Alzheimer's and Parkinson's disease. The confirmation of such diagnosis allows early detection and subsequent medical counseling that help specific patients to undergo clinically important drug trials. This provides a medical pathway to have better insight of neurogenesis and eventual cure of the neurodegenerative diseases. In this short review, we present recent advances in molecular diagnostics especially biomarkers and imaging spectroscopy for neurological diseases. We describe advances made in Alzheimer's disease (AD), Parkinson's disease (PD), Amyotrophic lateral sclerosis (ALS) and Huntington's disease (HD), and finally present a perspective on the future directions to provide a framework for further developments and refinements of molecular diagnostics to combat neurodegenerative disorders.

Ethical, legal, and practical issues in the control and regulation of suicide promotion and assistance over the Internet.

PubMed

Mishara, Brian L; Weisstub, David N

2007-02-01

The promotion of suicide and description of suicide methods on the Internet have led to widespread concern that legal control is mandated. Apart from value concerns pertaining to attitudes about suicide, the guarantee of freedom of expression presents a serious challenge to the introduction of restrictive laws. Recent developments in Australia and Europe are presented, noting jurisdictional complexity as an obstacle to effective application. Finally, scientific data of an epidemiological nature are revealed to be insufficient to warrant making causal assertions about the Internet and its relation to suicidal acts, including those of vulnerable populations. Recommendations are made with respect to public education, suicide prevention, and future research.

Integer programming applications: Bond trading, mortgage backed security financing, and FASB 115 accounting

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nauss, R.

1994-12-31

In this review we describe three integer programming applications involving fixed income securities. A bond trading model is presented that features a number of possible different objectives and collections of constraints including future interest rate scenarios. A mortgage backed security (MBS) financing model that accounts for potential defaults in the MBS is also presented. Finally we describe an approach to allocate collections of bank securities into three categories: hold to maturity, available for sale, or trading. Placement of securities in these categories affects the capital, net income, and liquidity of a bank according to new accounting rules promulgated by themore » Financial Accounting Standards Board.« less

Entity-Centric Abstraction and Modeling Framework for Transportation Architectures

NASA Technical Reports Server (NTRS)

Lewe, Jung-Ho; DeLaurentis, Daniel A.; Mavris, Dimitri N.; Schrage, Daniel P.

2007-01-01

A comprehensive framework for representing transpportation architectures is presented. After discussing a series of preceding perspectives and formulations, the intellectual underpinning of the novel framework using an entity-centric abstraction of transportation is described. The entities include endogenous and exogenous factors and functional expressions are offered that relate these and their evolution. The end result is a Transportation Architecture Field which permits analysis of future concepts under the holistic perspective. A simulation model which stems from the framework is presented and exercised producing results which quantify improvements in air transportation due to advanced aircraft technologies. Finally, a modeling hypothesis and its accompanying criteria are proposed to test further use of the framework for evaluating new transportation solutions.

Searching for Physics Beyond the Standard Model and Beyond

NASA Astrophysics Data System (ADS)

Abdullah, Mohammad

The hierarchy problem, convolved with the various known puzzles in particle physics, grants us a great outlook of new physics soon to be discovered. We present multiple approaches to searching for physics beyond the standard model. First, two models with a minimal amount of theoretical guidance are analyzed using existing or simulated LHC data. Then, an extension of the Minimal Supersymmetric Standard Model (MSSM) is studied with an emphasis on the cosmological implications as well as the current and future sensitivity of colliders, direct detection and indirect detection experiments. Finally, a more complete model of the MSSM is presented through which we attempt to resolve tension with observations within the context of gauge mediated supersymmetry breaking.

The Morphometrical and Histopathological Changes which were Observed after Topical Ozone Therapy on an Exophytic Fibrous Gingival Lesion: A Case Report.

PubMed

Patel, Punit Vaibhav; Gujjari, Sheela Kumar

2013-06-01

We are presenting 2 cases where ozone therapy was used in the form of ozonated oil on an exophytic fibrous gingival lesion. A 42-years female patient was selected, who presented with a mild to moderately painful, exophytic, fibrous lesion on the upper anterior gingiva. This gingival lesion was treated with 2ml of ozonated oil, thrice daily for one week. After the ozone therapy, the postoperative outcomes were measured and analyzed. Finally, the lesion was subjected to an excisional biopsy and a histopathological evaluation. After the ozone therapy, the patient revealed that there was less pain. On examination of the lesion, an improvement was observed in the clinical sign of the inflammation and also a reduction in the surface ulceration. During the final biopsy, less bleeding was observed. The morphometrical analysis showed a reduction in the size of the lesion. The histopathological analysis showed a reduction in the collagen fibres and in the inflammatory cells in the connective tissue stroma. Topical ozone therapy provides potential benefits for the treatment of exophytic gingival lesions. The observed benefits in present case report needs to be verified in future with well-controlled clinical trials.

Flight Test Results of VDL-3, 1090ES, and UAT Datalinks for Weather Information Communication

NASA Technical Reports Server (NTRS)

Griner, James

2006-01-01

This presentation describes final test results for the Weather Information Communications (WINCOMM) program at the NASA Glenn Research Center on flight testing of the 1090 Extended Squitter (1090ES), VDL Mode 3, and Universal Access Transceiver (UAT) data links as a medium for weather data exchange. It presents an architectural description of the use of 1090ES to meet the program objectives of sending turbulence information, the use of VDL Mode 3 to send graphical weather images, and the use of UAT for transmitting weather sensor data. This presentation provides a high level definition of the changes made to both avionics and ground-based receivers as well as the ground infrastructure used to support flight testing and future implementation. Summary of results from flight tests of these datalinks will also be presented.

Recent progress in synchrotron-based frequency-domain Fourier-transform THz-EPR.

PubMed

Nehrkorn, Joscha; Holldack, Karsten; Bittl, Robert; Schnegg, Alexander

2017-07-01

We describe frequency-domain Fourier-transform THz-EPR as a method to assign spin-coupling parameters of high-spin (S>1/2) systems with very large zero-field splittings. The instrumental foundations of synchrotron-based FD-FT THz-EPR are presented, alongside with a discussion of frequency-domain EPR simulation routines. The capabilities of this approach is demonstrated for selected mono- and multinuclear HS systems. Finally, we discuss remaining challenges and give an outlook on the future prospects of the technique. Copyright © 2017 Elsevier Inc. All rights reserved.

Testing gravity with EG: mapping theory onto observations

NASA Astrophysics Data System (ADS)

Leonard, C. Danielle; Ferreira, Pedro G.; Heymans, Catherine

2015-12-01

We present a complete derivation of the observationally motivated definition of the modified gravity statistic EG. Using this expression, we investigate how variations to theory and survey parameters may introduce uncertainty in the general relativistic prediction of EG. We forecast errors on EG for measurements using two combinations of upcoming surveys, and find that theoretical uncertainties may dominate for a futuristic measurement. Finally, we compute predictions of EG under modifications to general relativity in the quasistatic regime, and comment on the pros and cons of using EG to test gravity with future surveys.

Recent advances in noble metal based composite nanocatalysts: colloidal synthesis, properties, and catalytic applications.

PubMed

Xu, Yong; Chen, Lei; Wang, Xuchun; Yao, Weitang; Zhang, Qiao

2015-06-28

This Review article provides a report on progress in the synthesis, properties and catalytic applications of noble metal based composite nanomaterials. We begin with a brief discussion on the categories of various composite materials. We then present some important colloidal synthetic approaches to the composite nanostructures; here, major attention has been paid to bimetallic nanoparticles. We also introduce some important physiochemical properties that are beneficial from composite nanomaterials. Finally, we highlight the catalytic applications of such composite nanoparticles and conclude with remarks on prospective future directions.

Conducting Polyaniline Nanowire and Its Applications in Chemiresistive Sensing

PubMed Central

Song, Edward; Choi, Jin-Woo

2013-01-01

One dimensional polyaniline nanowire is an electrically conducting polymer that can be used as an active layer for sensors whose conductivity change can be used to detect chemical or biological species. In this review, the basic properties of polyaniline nanowires including chemical structures, redox chemistry, and method of synthesis are discussed. A comprehensive literature survey on chemiresistive/conductometric sensors based on polyaniline nanowires is presented and recent developments in polyaniline nanowire-based sensors are summarized. Finally, the current limitations and the future prospect of polyaniline nanowires are discussed. PMID:28348347

Thermal structure analyses for CSM testbed (COMET)

NASA Technical Reports Server (NTRS)

Xue, David Y.; Mei, Chuh

1994-01-01

This document is the final report for the project entitled 'Thermal Structure Analyses for CSM Testbed (COMET),' for the period of May 16, 1992 - August 15, 1994. The project was focused on the investigation and development of finite element analysis capability of the computational structural mechanics (CSM) testbed (COMET) software system in the field of thermal structural responses. The stages of this project consisted of investigating present capabilities, developing new functions, analysis demonstrations, and research topics. The appendices of this report list the detailed documents of major accomplishments and demonstration runstreams for future references.

1983 LTA technology assessment

NASA Technical Reports Server (NTRS)

Ashford, R. L.; Browning, R. G. E.; Levitt, B. B.; Mayer, N. J.; Woodward, D. E.

1983-01-01

Several aspects of LTA (lighter-than-air) technology development are reviewed. Technological developments of classical airships through 1974 are examined. A brief historical and technological summary of five specialized LTA equipment concepts is presented: metal-clad airships, free balloons, semibuoyant vehicles, high-altitude platforms, and tethered aerostats. Current LTA technology developments are reviewed with particular emphasis on VTOL airships capable of heavy lift and on long endurance types for coastal maritime patrol. Finally, the future prospects of LTA system development are considered with attention given to manned conventional and hybrid vehicles, tethered vehicles, and RPVs.

My Personal Comments on J-PARC

NASA Astrophysics Data System (ADS)

Nagamiya, Shoji

In this talk I present four topics excluding scientific aspects and/or a general overview of J-PARC, which will be described by the next speaker (J. M. Poutisou). Instead, I describe firstly a brief history of how J-PARC was born, as a view from me. Secondly the effects from two major accidents at J-PARC, the earthquake and the radioactive material leak accident, are described. Thirdly, I describe the future 5-year plan. Finally in the fourth, I would like to emphasize the importance of the internationalization at J-PARC.

Soccer in Indiana and models for non-leptonic decays of heavy flavours

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bigi, I.I.

1989-12-15

Various descriptions of non-leptonic charm decays are reviewed and their relative strengths and weaknesses are listed. I conclude that it is mainly (though no necessarily solely) a destructive interference in nonleptonic D{sup +} decays that shapes the decays of charm mesons. Some more subtle features in these decays are discussed in a preview of future research before I address the presently confused situation in D{sub s} decays. Finally I give a brief theoretical discussion of inclusive and exclusive non-leptonic decays of beauty mesons.

Peripheral inflammation and cognitive aging.

PubMed

Lim, Alvin; Krajina, Katarina; Marsland, Anna L

2013-01-01

Evidence suggests that inflammation, an innate immune response facilitating recovery from injury and pathogenic invasion, is positively associated with age-related cognitive decline and may play a role in risk for dementia. Physiological pathways linking the peripheral immune and central nervous systems are outlined, and studies linking inflammation with neurocognitive function are overviewed. We also present recent studies from our laboratory showing that midlife inflammation is related to cognitive function and brain morphology. Finally, potential implications for treatment, future directions, and limitations are discussed. Copyright © 2013 S. Karger AG, Basel.

Computing in high-energy physics

NASA Astrophysics Data System (ADS)

Mount, Richard P.

2016-04-01

I present a very personalized journey through more than three decades of computing for experimental high-energy physics, pointing out the enduring lessons that I learned. This is followed by a vision of how the computing environment will evolve in the coming ten years and the technical challenges that this will bring. I then address the scale and cost of high-energy physics software and examine the many current and future challenges, particularly those of management, funding and software-lifecycle management. Finally, I describe recent developments aimed at improving the overall coherence of high-energy physics software.

The Impact of Alcoholics Anonymous on other substance abuse related Twelve Step programs

PubMed Central

Laudet, Alexandre B.

2008-01-01

This chapter explores the influence of the AA model on self-help fellowships addressing problems of drug dependence. Fellowships that have adapted the 12-step recovery model to other substances of abuse are reviewed; next similarities and differences between AA and drug-recovery 12-step organizations are examined; finally, we present empirical findings on patterns of attendance and perceptions of AA and Narcotics Anonymous (NA) among polydrug dependent populations, many of whom are cross-addicted to alcohol. Future directions in 12-step research are noted in closing. PMID:19115764

Design of 3x3 Focusing Array for Heavy Ion Driver Final Report on CRADA TC-02082-04

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martovetsky, N.

This memo presents a design of a 3x3 quadrupole array for HIF. It contains 3 D magnetic field computations of the array build with racetrack coils with and without different shields. It is shown that it is possible to have a low error magnetic field in the cells and shield the stray fields to acceptable levels. The array design seems to be a practical solution to any size array for future multi-beam heavy ion fusion drivers.

The physics, chemistry and dynamics of explosions.

PubMed

Oran, Elaine S; Williams, Forman A

2012-02-13

The motivation for devoting a Theme Issue to explosions is discussed. As subsequent articles in the issue are written with the assumption that the reader has had a certain amount of previous exposure to the subject, some of the history and necessary background information are presented here. The topics on explosions that will be encountered in the remaining articles are previewed. Finally, several important future outstanding research problems, beyond those addressed in the following articles, are discussed, with the objective of complementing the coverage of explosions in this issue.

Gait recognition based on integral outline

NASA Astrophysics Data System (ADS)

Ming, Guan; Fang, Lv

2017-02-01

Biometric identification technology replaces traditional security technology, which has become a trend, and gait recognition also has become a hot spot of research because its feature is difficult to imitate and theft. This paper presents a gait recognition system based on integral outline of human body. The system has three important aspects: the preprocessing of gait image, feature extraction and classification. Finally, using a method of polling to evaluate the performance of the system, and summarizing the problems existing in the gait recognition and the direction of development in the future.

Meditation research, past, present, and future: perspectives from the Nalanda contemplative science tradition

PubMed Central

Loizzo, Joseph

2014-01-01

This article offers an overview of meditation research: its history, recent developments, and future directions. As the number and scope of studies grow, the field has converged with cognitive and affective neuroscience, and spawned many clinical applications. Recent work has shed light on the mechanisms and effects of diverse practices, and is entering a new phase where consensus and coherent paradigms are within reach. This article suggests an unusual path for future advancement: complementing conventional research with rigorous dialogue with the contemplative traditions that train expert meditators and best know the techniques. It explores the Nalanda tradition developed in India and preserved in Tibet, because its cumulative approach to contemplative methods produced a comprehensive framework that may help interpret data and guide research, and because its naturalistic theories and empirical methods may help bridge the gulf between science and other contemplative traditions. Examining recent findings and models in light of this framework, the article introduces the Indic map of the central nervous system and presents three testable predictions based on it. Finally, it reviews two studies that suggest that the multimodal Nalanda approach to contemplative learning is as well received as more familiar approaches, while showing promise of being more effective. PMID:24673149

Adjuvant chemotherapy for gastric cancer: Current evidence and future challenges

PubMed Central

Miceli, Rosalba; Tomasello, Gianluca; Bregni, Giacomo; Di Bartolomeo, Maria; Pietrantonio, Filippo

2014-01-01

Gastric cancer still represents one of the major causes of cancer mortality worldwide. Patients survival is mainly related to stage, with a high proportion of patients with metastatic disease at presentation. Thus, the cure rate largely depend upon surgical resection. Despite the additional, albeit small, benefit of adjuvant chemotherapy has been clearly demonstrated, no general consensus has been reached on the best treatment option. Moreover, the narrow therapeutic index of adjuvant chemotherapy (i.e., limited survival benefit with considerable toxicity) requires a careful assessment of expected risks and benefits for individual patients. Treatment choices vary widely based on the different geographic areas, with chemotherapy alone more often preferred in Europe or Asia and chemoradiotherapy in the United States. In the present review we discuss the current evidence and future challenges regarding adjuvant chemotherapy in curatively resected gastric cancer with particular emphasis on the recently completed landmark studies and meta-analyses. The most recent patient-level meta-analysis demonstrated the benefit of adjuvant chemotherapy over curative surgery; the same Authors also showed that disease-free survival may be used as a surrogate end-point for overall survival. We finally discuss future research issues such as the need of economic evaluations, development of prognostic or predictive biomarkers, and the unmet clinical need of trials comparing perioperative chemotherapy with adjuvant treatment. PMID:24782604

Utilization of case presentations in medical microbiology to enhance relevance of basic science for medical students

PubMed Central

Chamberlain, Neal R.; Stuart, Melissa K.; Singh, Vineet K.; Sargentini, Neil J.

2012-01-01

Background Small-group case presentation exercises (CPs) were created to increase course relevance for medical students taking Medical Microbiology (MM) and Infectious Diseases (ID) Methods Each student received a unique paper case and had 10 minutes to review patient history, physical exam data, and laboratory data. Students then had three minutes to orally present their case and defend why they ruled in or out each of the answer choices provided, followed by an additional three minutes to answer questions. Results Exam scores differed significantly between students who received the traditional lecture-laboratory curriculum (Group I) and students who participated in the CPs (Group II). In MM, median unit exam and final exam scores for Group I students were 84.4% and 77.8%, compared to 86.0% and 82.2% for Group II students (P<0.018; P<0.001; Mann-Whitney Rank Sum Test). Median unit and final ID exam scores for Group I students were 84.0% and 80.0%, compared to 88.0% and 86.7% for Group II students (P<0.001; P<0.001). Conclusion Students felt that the CPs improved their critical thinking and presentation skills and helped to prepare them as future physicians. PMID:22435014

Contribution of past and future self-defining event networks to personal identity.

PubMed

Demblon, Julie; D'Argembeau, Arnaud

2017-05-01

Personal identity is nourished by memories of significant past experiences and by the imagination of meaningful events that one anticipates to happen in the future. The organisation of such self-defining memories and prospective thoughts in the cognitive system has received little empirical attention, however. In the present study, our aims were to investigate to what extent self-defining memories and future projections are organised in networks of related events, and to determine the nature of the connections linking these events. Our results reveal the existence of self-defining event networks, composed of both memories and future events of similar centrality for identity and characterised by similar identity motives. These self-defining networks expressed a strong internal coherence and frequently organised events in meaningful themes and sequences (i.e., event clusters). Finally, we found that the satisfaction of identity motives in represented events and the presence of clustering across events both contributed to increase in the perceived centrality of events for the sense of identity. Overall, these findings suggest that personal identity is not only nourished by representations of significant past and future events, but also depends on the formation of coherent networks of related events that provide an overarching meaning to specific life experiences.

Moisture fluxes towards Switzerland: investigating future changes in CMIP5 climate models

NASA Astrophysics Data System (ADS)

Fazan, Valerie; Martius, Olivia; Martynov, Andrey; Panziera, Luca

2017-04-01

High integrated vapor transport (IVT) in the atmosphere directed perpendicular to the orography is an important proxy for flood related precipitation in many mountainous areas around the world. Here we focus on flood related IVT and its changes in a warmer climate in Switzerland, where most high-impact floods events in the past 30 years were connected to exceptional IVT upstream of the mountains. Our study aims at investigating how these critical IVT values are projected to evolve in the future in a changing climate. The IVT is computed from 15 CMIP5 climate models for the past (1950-2005) and the future (2006-2100) under the RCP 8.5 scenario ("business as usual"). In order to check the accuracy of the models and the effect of the varying resolution, present day IVT from the CMIP5 models is compared with the ERA-Interim reanalysis data (period 1979-2015). A quantile mapping technique is then used to correct biases. The same bias corrections are applied to the future (2006-2100) IVT data. Finally, future changes in extreme IVT are investigated. This includes an analysis of changes in the magnitude and direction of the moisture flux in the different seasons for different regions in Switzerland.

Model-Unified Planning and Execution for Distributed Autonomous System Control

NASA Technical Reports Server (NTRS)

Aschwanden, Pascal; Baskaran, Vijay; Bernardini, Sara; Fry, Chuck; Moreno, Maria; Muscettola, Nicola; Plaunt, Chris; Rijsman, David; Tompkins, Paul

2006-01-01

The Intelligent Distributed Execution Architecture (IDEA) is a real-time architecture that exploits artificial intelligence planning as the core reasoning engine for interacting autonomous agents. Rather than enforcing separate deliberation and execution layers, IDEA unifies them under a single planning technology. Deliberative and reactive planners reason about and act according to a single representation of the past, present and future domain state. The domain state behaves the rules dictated by a declarative model of the subsystem to be controlled, internal processes of the IDEA controller, and interactions with other agents. We present IDEA concepts - modeling, the IDEA core architecture, the unification of deliberation and reaction under planning - and illustrate its use in a simple example. Finally, we present several real-world applications of IDEA, and compare IDEA to other high-level control approaches.

A look at V/STOL for business aircraft.

NASA Technical Reports Server (NTRS)

Feistel, T. W.; Stewart, E. C.; Gerdes, R. M.; Smith, K. R., Jr.

1972-01-01

Attempt to ascertain the economic viability of the V/STOL capability for business aircraft and the manner in which this viability depends on the aircraft concept. A cost-benefit analysis is presented which indicates that a VTOL business aircraft would be more viable economically than a contemporary turbine-powered business aircraft. The combination of traveler's time value and trip distance for which each aircraft dominates is shown. The significance of disk loading in V/STOL concept application is discussed, and preliminary design configuration studies for three different business-aircraft-sized V/STOLs, using three concepts covering a range of disk loading, are presented as examples. Finally, a discussion of operational aspects of interest to future users of V/STOL business aircraft is presented which centers around the requirements for routine IFR terminal-area operations.

The history of transportation, with a peak into the future

NASA Technical Reports Server (NTRS)

Anderson, John D., Jr.

1996-01-01

In the first part of this presentation, a general historical review of the heydays of various modes of transportation will be given, where 'heydays' will be interpreted as periods of fundamental technological development. With this as background, focus will then be placed on the airplane -- the mode of transportation that has changed the world in the 20th century, and which in the minds of many has been the most important technological development in this century. The technical history of air transportation (the airplane) will be reviewed, with special emphasis on the aerodynamic evolution of the airplane. Some specific examples of pivotal technical advances (and breakthroughs) from the history of applied aerodynamics will be discussed. Finally, this historical perspective will be used to help us peek into the future of transportation in the 21st century.

The history and future of accelerator radiological protection.

PubMed

Thomas, R H

2001-01-01

The development of accelerator radiological protection from the mid-1930s, just after the invention of the cyclotron, to the present day is described. Three major themes--physics, personalities and politics--are developed. In the sections describing physics the development of shielding design though measurement, radiation transport calculations, the impact of accelerators on the environment and dosimetry in accelerator radiation fields are described. The discussion is limited to high-energy, high-intensity electron and proton accelerators. The impact of notable personalities on the development of both the basic science and on the accelerator health physics profession itself is described. The important role played by scholars and teachers is discussed. In the final section. which discusses the future of accelerator radiological protection, some emphasis is given to the social and political aspects that must he faced in the years ahead.

Nuclear threat on the Korean peninsula: The present and the future. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kang, S.

1994-04-01

Forty years after they were divided by the Cold War, South and North Korea are closer to reunification than ever before. However, North Korea's nuclear weapons program might cause South Koreans to be much less sure about reunification. Today the Cold War is over, but the Korean peninsula is still divided into two Koreas despite the new era of reconciliation. Since December 1991 when a non-aggression pact was signed barring nuclear weapons, North Korea has pursued its nuclear weapon development. In March 1993, North Korea declared its intention to withdraw from the Nuclear Non-Proliferation Treaty, and has been refusing amore » full inspection of its nuclear program. North Korea's nuclear issue is an international issue today. This paper discusses 'what threat we have today' and 'what should be done in the future.'.« less

The European nanometrology landscape.

PubMed

Leach, Richard K; Boyd, Robert; Burke, Theresa; Danzebrink, Hans-Ulrich; Dirscherl, Kai; Dziomba, Thorsten; Gee, Mark; Koenders, Ludger; Morazzani, Valérie; Pidduck, Allan; Roy, Debdulal; Unger, Wolfgang E S; Yacoot, Andrew

2011-02-11

This review paper summarizes the European nanometrology landscape from a technical perspective. Dimensional and chemical nanometrology are discussed first as they underpin many of the developments in other areas of nanometrology. Applications for the measurement of thin film parameters are followed by two of the most widely relevant families of functional properties: measurement of mechanical and electrical properties at the nanoscale. Nanostructured materials and surfaces, which are seen as key materials areas having specific metrology challenges, are covered next. The final section describes biological nanometrology, which is perhaps the most interdisciplinary applications area, and presents unique challenges. Within each area, a review is provided of current status, the capabilities and limitations of current techniques and instruments, and future directions being driven by emerging industrial measurement requirements. Issues of traceability, standardization, national and international programmes, regulation and skills development will be discussed in a future paper.

Cryogenic fluid management (base R/T): Cryogenic fluid systems, Cryogenic Orbital Nitrogen Experiment (CONE), Cryogenic Orbital Hydrogen Experiment (COHE). (Transportation focused technology)

NASA Technical Reports Server (NTRS)

Symons, Pat

1991-01-01

The topics presented are covered in viewgraph form. The concluded remarks are: (1) advanced cryogenic fluid systems technology is enhancing or enabling to all known transportation scenarios for space exploration; (2) an integrated/coordinated program involving LeRC/MSFC has been formulated to address all known CFM needs - new needs should they develop, can be accommodated within available skills/facilities; (3) all required/experienced personnel and facilities are finally in place - data from initial ground-based experiments is being collected and analyzed - small scale STS experiments are nearing flight - program is beginning to yield significant results; (4) future proposed funding to primarily come from two sources; and (5) cryogenic fluid experimentation is essential to provide required technology and assure implementation in future NASA missions.

The European nanometrology landscape

NASA Astrophysics Data System (ADS)

Leach, Richard K.; Boyd, Robert; Burke, Theresa; Danzebrink, Hans-Ulrich; Dirscherl, Kai; Dziomba, Thorsten; Gee, Mark; Koenders, Ludger; Morazzani, Valérie; Pidduck, Allan; Roy, Debdulal; Unger, Wolfgang E. S.; Yacoot, Andrew

2011-02-01

This review paper summarizes the European nanometrology landscape from a technical perspective. Dimensional and chemical nanometrology are discussed first as they underpin many of the developments in other areas of nanometrology. Applications for the measurement of thin film parameters are followed by two of the most widely relevant families of functional properties: measurement of mechanical and electrical properties at the nanoscale. Nanostructured materials and surfaces, which are seen as key materials areas having specific metrology challenges, are covered next. The final section describes biological nanometrology, which is perhaps the most interdisciplinary applications area, and presents unique challenges. Within each area, a review is provided of current status, the capabilities and limitations of current techniques and instruments, and future directions being driven by emerging industrial measurement requirements. Issues of traceability, standardization, national and international programmes, regulation and skills development will be discussed in a future paper.

Positioning navigation and timing service applications in cyber physical systems

NASA Astrophysics Data System (ADS)

Qu, Yi; Wu, Xiaojing; Zeng, Lingchuan

2017-10-01

The positioning navigation and timing (PNT) architecture was discussed in detail, whose history, evolvement, current status and future plan were presented, main technologies were listed, advantages and limitations of most technologies were compared, novel approaches were introduced, and future capacities were sketched. The concept of cyber-physical system (CPS) was described and their primary features were interpreted. Then the three-layer architecture of CPS was illustrated. Next CPS requirements on PNT services were analyzed, including requirements on position reference and time reference, requirements on temporal-spatial error monitor, requirements on dynamic services, real-time services, autonomous services, security services and standard services. Finally challenges faced by PNT applications in CPS were concluded. The conclusion was expected to facilitate PNT applications in CPS, and furthermore to provide references to the design and implementation of both architectures.

Microbial fuel cells in saline and hypersaline environments: Advancements, challenges and future perspectives.

PubMed

Grattieri, Matteo; Minteer, Shelley D

2018-04-01

This review is aimed to report the possibility to utilize microbial fuel cells for the treatment of saline and hypersaline solutions. An introduction to the issues related with the biological treatment of saline and hypersaline wastewater is reported, discussing the limitation that characterizes classical aerobic and anaerobic digestions. The microbial fuel cell (MFC) technology, and the possibility to be applied in the presence of high salinity, is discussed before reviewing the most recent advancements in the development of MFCs operating in saline and hypersaline conditions, with their different and interesting applications. Specifically, the research performed in the last 5years will be the main focus of this review. Finally, the future perspectives for this technology, together with the most urgent research needs, are presented. Copyright © 2017 Elsevier B.V. All rights reserved.

Fifth IPCC Assessment Report Now Out

NASA Astrophysics Data System (ADS)

Kundzewicz, Zbigniew W.

2014-01-01

The Fifth Assessment Report (AR5) of the Intergovernmental Panel on Climate Change (IPCC) is now available. It provides policymakers with an assessment of information on climate change, its impacts and possible response options (adaptation and mitigation). Summaries for policymakers of three reports of IPCC working groups and of the Synthesis Report have now been approved by IPCC plenaries. This present paper reports on the most essential findings in AR5. It briefly informs on the contents of reports of all IPCC working groups. It discusses the physical science findings, therein observed changes (ubiquitous warming, shrinking cryosphere, sea level rise, changes in precipitation and extremes, and biogeochemical cycles). It deals with the drivers of climate change, progress in climate system understanding (evaluation of climate models, quantification of climate system responses), and projections for the future. It reviews impacts, adaptation and vulnerability, including observed changes, key risks, key reasons for concern, sectors and systems, and managing risks and building resilience. Finally, mitigation of climate change is discussed, including greenhouse gas emissions in the past, present and future, and mitigation in sectors. It is hoped that the present article will encourage the readership of this journal to dive into the AR5 report that provides a wealth of useful information.

Simulating the Past, Present and Future of the Upper Troposphere and Lower Stratosphere

NASA Astrophysics Data System (ADS)

Gettelman, Andrew; Hegglin, Michaela

2010-05-01

A comprehensive assessment of coupled chemistry climate model (CCM) performance in the upper troposphere and lower stratosphere has been conducted with 18 models. Both qualitative and quantitative comparisons of model representation of UTLS dynamical, radiative and chemical structure have been conducted, using a collection of quantitative grading techniques. The models are able to reproduce the observed climatology of dynamical, radiative and chemical structure in the tropical and extratropical UTLS, despite relatively coarse vertical and horizontal resolution. Diagnostics of the Tropical Tropopause Layer (TTL), Tropopause Inversion Layer (TIL) and Extra-tropical Transition Layer (ExTL) are analyzed. The results provide new insight into the key processes that govern the dynamics and transport in the tropics and extra-tropicsa. The presentation will explain how models are able to reproduce key features of the UTLS, what features they do not reproduce, and why. Model trends over the historical period are also assessed and interannual variability is included in the metrics. Finally, key trends in the UTLS for the future with a given halogen and greenhouse gas scenario are presented, indicating significant changes in tropopause height and temperature, as well as UTLS ozone concentrations in the 21st century due to climate change and ozone recovery.

SensorWeb 3G: Extending On-Orbit Sensor Capabilities to Enable Near Realtime User Configurability

NASA Technical Reports Server (NTRS)

Mandl, Daniel; Cappelaere, Pat; Frye, Stuart; Sohlberg, Rob; Ly, Vuong; Chien, Steve; Tran, Daniel; Davies, Ashley; Sullivan, Don; Ames, Troy;

78 FR 66621 - Protection of Collateral of Counterparties to Uncleared Swaps; Treatment of Securities in a...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-06

...The Commodity Futures Trading Commission (the ``Commission'') is issuing final rules implementing new statutory provisions enacted by Title VII of the Dodd-Frank Wall Street Reform and Consumer Protection Act (the ``Dodd-Frank Act''). Specifically, the final rule contained herein imposes requirements on swap dealers (``SDs'') and major swap participants (``MSPs'') with respect to the treatment of collateral posted by their counterparties to margin, guarantee, or secure uncleared swaps. Additionally, the final rule includes revisions to ensure that, for purposes of subchapter IV of chapter 7 of the Bankruptcy Code, securities held in a portfolio margining account that is a futures account or a Cleared Swaps Customer Account constitute ``customer property''; and owners of such account constitute ``customers.''

Employer Policies and Practices to Manage and Prevent Disability: Foreword to the Special Issue.

PubMed

Shaw, William S; Main, Chris J; Pransky, Glenn; Nicholas, Michael K; Anema, Johannes R; Linton, Steven J

2016-12-01

Purpose Employer policies and practices have been shown to impact workplace disability, but research in this area has waned in recent years despite an aging workforce, a growing prevalence of chronic health conditions, and a larger proportion of working-age adults on permanent work disability in many jurisdictions. The purpose of this article is to describe the background rationale and methodology for an invited conference designed to improve research of employer strategies to curtail work disability. Methods A multidisciplinary team of 26 international researchers with published research in employer-based disability management or related fields were invited to attend a 3-day conference in Hopkinton, Massachusetts, USA. The overall goal was to review the status of current research of workplace disability management and prevention, examine its relevance for employer decision-making, compare conceptual frameworks or theoretical perspectives, and recommend future research directions. Working groups were organized and draft manuscripts were prepared in advance. Conference activities included working group presentations and critiques, discussions with a panel of industry consultants and advisors, group interaction and debate, generation of final recommendations, and manuscript revision. Results/Conclusion Six principal domains were established with respect to future research: (a) further elucidation of the key workplace factors that buffer the disabling effects of injury and illness; (b) more innovative and feasible options for workplace intervention; (c) measurement of workplace-relevant disability outcomes; (d) a stronger theoretical framework for understanding the factors behind employer uptake and implementation; (e) a focus on special clinical populations and occupations where disability risk is most troubling; and (f) better representation of workers and employers that reflect the diverse and changing nature of work. Final comments and recommendations of the working groups are presented in the following six articles in this special issue of the Journal of Occupational Rehabilitation. Conference attendees recommended changes in methodology, collaboration strategies, and theoretical perspectives to improve the practical and scientific impact of future research of employer practices.

Accomplishments of the Abrupt Wing Stall (AWS) Program and Future Research Requirements

NASA Technical Reports Server (NTRS)

Hall, Robert M.; Woodson, Shawn H.; Chambers, Joseph R.

2003-01-01

The Abrupt Wing Stall (AWS) Program has addressed the problem of uncommanded lateral motions, such as wing drop and wing rock, at transonic speeds. The genesis of this Program was the experience of the F/A-18E/F Program in the late 199O's, when wing drop was discovered in the heart of the maneuver envelope for the pre-production aircraft. While the F/A-18E/F problem was subsequently corrected by a leading-edge flap scheduling change and the addition of a porous door to the wing fold fairing, the AWS Program was initiated as a national response to the lack of technology readiness available at the time of the F/A-18E/F Development Program. The AWS Program objectives were to define causal factors for the F/A-18E/F experience, to gain insights into the flow physics associated with wing drop, and to develop methods and analytical tools so that future programs could identify this type of problem before going to flight test. The paper reviews, for the major goals of the AWS Program, the status of the technology before the program began, the program objectives, accomplishments, and impacts. Lessons learned are presented for the benefit of future programs that must assess whether a vehicle will have uncommanded lateral motions before going to flight test. Finally, recommended future research needs are presented in light of the AWS Program experience.

76 FR 40817 - Implementation of Section 224 of the Act; A National Broadband Plan for Our Future

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-12

...-50] Implementation of Section 224 of the Act; A National Broadband Plan for Our Future AGENCY... information collection requirements. The Office of Management and Budget (OMB) gave approval for these..., Implementation of Section 224 of the Act; A National Broadband Plan for Our Future. DATES: The final rules...

Interactive effects of ocean acidification and warming on coral reef associated epilithic algal communities under past, present-day and future ocean conditions

NASA Astrophysics Data System (ADS)

Vogel, N.; Cantin, N. E.; Strahl, J.; Kaniewska, P.; Bay, L.; Wild, C.; Uthicke, S.

2016-06-01

Epilithic algal communities play critical ecological roles on coral reefs, but their response to individual and interactive effects of ocean warming (OW) and ocean acidification (OA) is still largely unknown. We investigated growth, photosynthesis and calcification of early epilithic algal community assemblages exposed for 6 months to four temperature profiles (-1.1, ±0.0, +0.9, +1.6 °C) that were crossed with four carbon dioxide partial pressure (pCO2) levels (360, 440, 650, 940 µatm), under flow-through conditions and natural light regimes. Additionally, we compared the cover of heavily calcified crustose coralline algae (CCA) and lightly calcified red algae of the genus Peyssonnelia among treatments. Increase in cover of epilithic communities showed optima under moderately elevated temperatures and present pCO2, while cover strongly decreased under high temperatures and high-pCO2 conditions, particularly due to decreasing cover of CCA. Similarly, community calcification rates were strongly decreased at high pCO2 under both measured temperatures. While final cover of CCA decreased under high temperature and pCO2 (additive negative effects), cover of Peyssonnelia spp. increased at high compared to annual average and moderately elevated temperatures. Thus, cover of Peyssonnelia spp. increased in treatment combinations with less CCA, which was supported by a significant negative correlation between organism groups. The different susceptibility to stressors most likely derived from a different calcification intensity and/or mineral. Notably, growth of the epilithic communities and final cover of CCA were strongly decreased under reduced-pCO2 conditions compared to the present. Thus, CCA may have acclimatized from past to present-day pCO2 conditions, and changes in carbonate chemistry, regardless in which direction, negatively affect them. However, if epilithic organisms cannot further acclimatize to OW and OA, the interacting effects of both factors may change epilithic communities in the future, thereby likely leading to reduced reef stability and recovery.

Promising Practices and Programs: Current Efforts and Future Directions

ERIC Educational Resources Information Center

Crisp, Gloria

2016-01-01

The final chapter of the issue provides a synthesis of the first eight chapters, offers conclusions and recommendations, and considers future directions regarding practices and programs with promise for high impact at community colleges around the country.

Tourism's impact on future transportation needs

DOT National Transportation Integrated Search

2002-02-01

This report focuses on the changes evolving in the tourist industry and their impact on future transportation needs. First, the report concentrates on the changing of the demographic guard--from Baby Boomers to Generation Xers, and finally, to the en...

A healthier future for all Australians: an overview of the final report of the National Health and Hospitals Reform Commission.

PubMed

Bennett, Christine C

2009-10-05

After extensive community and health industry consultation, the final report of the National Health and Hospitals Reform Commission, A healthier future for all Australians, was presented to the Australian Government on 30 June 2009. The reform agenda aims to tackle major access and equity issues that affect health outcomes for people now; redesign our health system so that it is better positioned to respond to emerging challenges; and create an agile, responsive and self-improving health system for long-term sustainability. The 123 recommendations are grouped in four themes: Taking responsibility: supporting greater individual and collective action to build good health and wellbeing. Connecting care: delivering comprehensive care for people over their lifetime, by strengthening primary health care, reshaping hospitals, improving subacute care, and opening up greater consumer choice and competition in aged care services. Facing inequities: taking action to tackle the causes and impact of health inequities, focusing on Aboriginal and Torres Strait Islander people, people in rural and remote areas, and access to mental health and dental services. Driving quality performance: having leadership and systems to achieve the best use of people, resources and knowledge, including "one health system" with national leadership and local delivery, revised funding arrangements, and changes to health workforce education, training and practice.

Comet/Asteroid Protection System: Concept Study Executive Summary

NASA Technical Reports Server (NTRS)

Mazanek, Daniel D.

2005-01-01

Many of the major issues have been identified for a futuristic capability to protect against impacting comets and asteroids, and a preliminary space-based concept has been envisioned. Some of the basic concept elements, approaches, methodologies, and features have been identified. When contemplating the ability to monitor comets and asteroids continuously, there are many trade-offs between orbiting observatories and detection systems on planetary bodies without an atmosphere. Future orbit modification techniques have the potential for rapid and controlled alteration of NEO orbits, provided that high-power, compatible thermal management systems are developed. Much additional work and analysis are required to identify a final system concept, and many trade studies need to be performed to select the best mix of system capability, reliability, maintainability, and cost. Finally, it is fully appreciated that at the present time space systems are much more costly than terrestrial-based systems. Hopefully, this will change in the future. Regardless, understanding what it would take to defend against a much wider range of the impact threat will foster ideas, innovations, and technologies that could one day enable the development of such a system. This understanding is vital to provide ways of reducing the costs and quantifying the benefits that are achievable with a system like CAPS.

Hydro-meteorological drought event sets in the UK based on a large ensemble of global-regional climate simulations: climatology, drivers and changes in the future

NASA Astrophysics Data System (ADS)

Guillod, B. P.; Massey, N.; Otto, F. E. L.; Allen, M. R.; Jones, R.; Hall, J. W.

2016-12-01

Extreme events being rare by definition, accurately quantifying the probabilities associated with a given event is difficult. This is particularly true for droughts, for which only few events are available in the observational record owing to their long-lasting characteristics. The MaRIUS project (Managing the Risks, Impacts and Uncertainties of drought and water Scarcity) aims at quantifying present and future risks associated with droughts in the UK. To do so, a large number of modelled weather time series for "synthetic" drought events are being fed into hydrological and impact models to assess their impacts on various sectors (social sciences, economy, industry, agriculture, and ecosystems). Here, we present and analyse the hydro-meteorological drought event sets that have been produced with a new version of weather@home [1] for MaRIUS. Using idle processor time on volunteers' computers around the world, we have run a very large number (10'000s) of Global Climate Model simulations, downscaled at 25km over Europe by a nested Regional Climate Model. Simulations include the past 100 years as well as two future time slices (2030s and 2080s), and provide a large number of sequences of spatio-temporally coherent weather, which are consistent with the boundary forcing such as the ocean, greenhouse gases and solar forcing. Beside presenting the methodology and validation of the event sets, we provide insights into drought risk in the UK and the drivers of drought. In particular, we examine their sensitivity to sea surface temperature and sea ice patterns, both in the recent past and for future projections. How drought risk in the UK can be expected to change in the future will also be discussed. Finally, we assess the applicability of this methodology to other regions. Reference: [1] Massey, N. et al., 2014, Q. J. R. Meteorol. Soc.

Prediction of future subsurface temperatures in Korea

NASA Astrophysics Data System (ADS)

Lee, Y.; Kim, S. K.; Jeong, J.; SHIN, E.

2017-12-01

The importance of climate change has been increasingly recognized because it has had the huge amount of impact on social, economic, and environmental aspect. For the reason, paleoclimate change has been studied intensively using different geological tools including borehole temperatures and future surface air temperatures (SATs) have been predicted for the local areas and the globe. Future subsurface temperatures can have also enormous impact on various areas and be predicted by an analytical method or a numerical simulation using measured and predicted SATs, and thermal diffusivity data of rocks. SATs have been measured at 73 meteorological observatories since 1907 in Korea and predicted at same locations up to the year of 2100. Measured SATs at the Seoul meteorological observatory increased by about 3.0 K from the year of 1907 to the present. Predicted SATs have 4 different scenarios depending on mainly CO2 concentration and national action plan on climate change in the future. The hottest scenario shows that SATs in Korea will increase by about 5.0 K from the present to the year of 2100. In addition, thermal diffusivity values have been measured on 2,903 rock samples collected from entire Korea. Data pretreatment based on autocorrelation analysis was conducted to control high frequency noise in thermal diffusivity data. Finally, future subsurface temperatures in Korea were predicted up to the year of 2100 by a FEM simulation code (COMSOL Multiphysics) using measured and predicted SATs, and thermal diffusivity data in Korea. At Seoul, the results of predictions show that subsurface temperatures will increase by about 5.4 K, 3.0 K, 1.5 K, and 0.2 K from the present to 2050 and then by about 7.9 K, 4.8 K, 2.5 K, and 0.5 K to 2100 at the depths of 10 m, 50 m, 100 m, and 200 m, respectively. We are now proceeding numerical simulations for subsurface temperature predictions for 73 locations in Korea.

The use of biopharmaceutic classification of drugs in drug discovery and development: current status and future extension.

PubMed

Lennernäs, Hans; Abrahamsson, Bertil

2005-03-01

Bioavailability (BA) and bioequivalence (BE) play a central role in pharmaceutical product development and BE studies are presently being conducted for New Drug Applications (NDAs) of new compounds, in supplementary NDAs for new medical indications and product line extensions, in Abbreviated New Drug Applications (ANDAs) of generic products and in applications for scale-up and post-approval changes. The Biopharmaceutics Classification System (BCS) has been developed to provide a scientific approach for classifying drug compounds based on solubility as related to dose and intestinal permeability in combination with the dissolution properties of the oral immediaterelease (IR) dosage form. The aim of the BCS is to provide a regulatory tool for replacing certain BE studies by accurate in-vitro dissolution tests. The aim of this review is to present the status of the BCS and discuss its future application in pharmaceutical product development. The future application of the BCS is most likely increasingly important when the present framework gains increased recognition, which will probably be the case if the BCS borders for certain class II and III drugs are extended. The future revision of the BCS guidelines by the regulatory agencies in communication with academic and industrial scientists is exciting and will hopefully result in an increased applicability in drug development. Finally, we emphasize the great use of the BCS as a simple tool in early drug development to determine the rate-limiting step in the oral absorption process, which has facilitated the information between different experts involved in the overall drug development process. This increased awareness of a proper biopharmaceutical characterization of new drugs may in the future result in drug molecules with a sufficiently high permeability, solubility and dissolution rate, and that will automatically increase the importance of the BCS as a regulatory tool over time.

Thyroid hormone analogs for the treatment of dyslipidemia: past, present, and future.

PubMed

Delitala, Alessandro P; Delitala, Giuseppe; Sioni, Paolo; Fanciulli, Giuseppe

2017-11-01

Treatment of dyslipidemia is a major burden for public health. Thyroid hormone regulates lipid metabolism by binding the thyroid hormone receptor (TR), but the use of thyroid hormone to treat dyslipidemia is not indicated due to its deleterious effects on heart, bone, and muscle. Thyroid hormone analogs have been conceived to selectively activate TR in the liver, thus reducing potential side-effects. The authors searched the PubMed database to review TR and the action of thyromimetics in vitro and in animal models. Then, all double-blind, placebo controlled trials that analyzed the use of thyroid hormone analog for the treatment of dyslipidemia in humans were included. Finally, the ongoing research on the use of TR agonists was searched, searching the US National Institutes of Health Registry and the WHO International Clinical Trial Registry Platform (ICTRP). Thyromimetics were tested in humans for the treatment of dyslipidemia, as a single therapeutic agent or as an add-on therapy to the traditional lipid-lowering drugs. In most trials, thyromimetics lowered total cholesterol, low-density lipoprotein cholesterol, and triglycerides, but their use has been associated with adverse side-effects, both in pre-clinical studies and in humans. The use of thyromimetics for the treatment of dyslipidemia is not presently recommended. Future possible clinical applications might include their use to promote weight reduction. Thyromimetics might also represent an interesting alternative, both for the treatment of non-alcoholic steatohepatitis, and type 2 diabetes due to their positive effects on insulin sensitivity. Finally, additional experimental and clinical studies are needed for a better comprehension of the effect(s) of a long-term therapy.

Activity status and future plans for the Optical Laboratory of the National Astronomical Research Institute of Thailand

NASA Astrophysics Data System (ADS)

Buisset, Christophe; Poshyachinda, Saran; Soonthornthum, Boonrucksar; Prasit, Apirat; Alagao, Mary Angelie; Choochalerm, Piyamas; Wanajaroen, Weerapot; Lepine, Thierry; Rabbia, Yves; Aukkaravittayapun, Suparerk; Leckngam, Apichat; Thummasorn, Griangsak; Ngernsujja, Surin; Inpan, Anuphong; Kaewsamoet, Pimon; Lhospice, Esther; Meemon, Panomsak; Artsang, Pornapa; Suwansukho, Kajpanya; Sirichote, Wichit; Paenoi, Jitsupa

2018-03-01

The National Astronomical Research Institute of Thailand (NARIT) has developed since June 2014 an optical laboratory that comprises all the activities and facilities related to the research and development of new instruments in the following areas: telescope design, high dynamic and high resolution imaging systems and spectrographs. The facilities include ZEMAX and Solidwork software for design and simulation activities as well as an optical room with all the equipment required to develop optical setup with cutting-edge performance. The current projects include: i) the development of a focal reducer for the 2.3 m Thai National Telescope (TNT), ii) the development of the Evanescent Wave Coronagraph dedicated to the high contrast observations of star close environment and iii) the development of low resolution spectrographs for the Thai National Telescope and for the 0.7 m telescopes of NARIT regional observatories. In each project, our activities start from the instrument optical and mechanical design to the simulation of the performance, the development of the prototype and finally to the final system integration, alignment and tests. Most of the mechanical parts are manufactured by using the facilities of NARIT precision mechanical workshop that includes a 3-axis Computer Numerical Control (CNC) to machine the mechanical structures and a Coordinate Measuring Machine (CMM) to verify the dimensions. In this paper, we give an overview of the optical laboratory activities and of the associated facilities. We also describe the objective of the current projects, present the specifications and the design of the instruments and establish the status of development and we present our future plans.

[Final voluntary assessment for Traumatology and Orthopaedic Surgery medical residents: a report on the results and a look at the future].

PubMed

Urda, A; Ezquerra, L; Albareda, J; Baeza-Noci, J; Blanco, A; Cáceres, E; Martínez-Grande, M; Nardi, J; Yunta, A; Marco, F

2012-01-01

The idea of establishing an examination that accredits the training of the specialists in orthopaedic surgery at the end of their educational period as residents is subject to controversy. With the aim of encouraging the development of this examination, the present members of the National Commission of the Specialty of Orthopaedics (CNE) have reviewed the results obtained in previous examination. The results of the voluntary final exam for Orthopaedics residents, and of the surveys of participant opinions for the years 2006 to 2011 are presented. The total number of participants was 231, growing from 19 in 2005, to 71 in 2011. The overall mean score in the period reviewed (2006-2011) was 6.72 out of 10 points. In these 6 years, 9 participants failed (4.25%). The mean score for the test was 7.57. The overall mean score of the oral exam was 6.57. The worst results were obtained in the general knowledge section of the oral examination. Nobody has ever failed the section on reconstruction of the lower extremity. The upper extremity section in the oral examination achieves the best average results. The examination has established its place in the structure of orthopaedic resident training in our country, even without making it official by the Administration. We must positively acknowledge those candidates who chose to take the examination and be evaluated by their peers in order to prove their qualification and distinction. This recognition will be the best encouragement for future generations. Copyright © 2011 SECOT. Published by Elsevier Espana. All rights reserved.

Nanomaterial characterization through image treatment, 3D reconstruction and AI techniques

NASA Astrophysics Data System (ADS)

Lopez de Uralde Huarte, Juan Jose

Nanotechnology is not only the science of the future, but it is indeed the science of today. It is used in all sectors, from health to energy, including information technologies and transport. For the present investigation, we have taken carbon black as a use case. This nanomaterial is mixed with a wide variety of materials to improve their properties, like abrasion resistance, tire and plastic wear or tinting strength in pigments. Nowadays, indirect methods of analysis, like oil absorption or nitrogen adsorption are the most common techniques of the nanomaterial industry. These procedures measure the change in the physical state while adding oil and nitrogen. In this way, the superficial area is estimated and related with the properties of the material. Nevertheless, we have chosen to improve the existent direct methods, which consist in analysing microscopy images of nanomaterials. We have made progress in the image processing treatments and in the extracted features. In fact, some of them have overcome the existing features in the literature. In addition, we have applied, for the first time in the literature, machine learning to aggregate categorization. In this way, we identify automatically their morphology, which will determine the final properties of the material that is mixed with. Finally, we have presented an aggregate reconstruction genetic algorithm that, with only two orthogonal images, provides more information than a tomography, which needs a lot of images. To summarize, we have improved the state of the art in direct analysing techniques, allowing in the near future the replacement of the current indirect techniques.

On Target Localization Using Combined RSS and AoA Measurements

PubMed Central

Beko, Marko; Dinis, Rui

2018-01-01

This work revises existing solutions for a problem of target localization in wireless sensor networks (WSNs), utilizing integrated measurements, namely received signal strength (RSS) and angle of arrival (AoA). The problem of RSS/AoA-based target localization became very popular in the research community recently, owing to its great applicability potential and relatively low implementation cost. Therefore, here, a comprehensive study of the state-of-the-art (SoA) solutions and their detailed analysis is presented. The beginning of this work starts by considering the SoA approaches based on convex relaxation techniques (more computationally complex in general), and it goes through other (less computationally complex) approaches, as well, such as the ones based on the generalized trust region sub-problems framework and linear least squares. Furthermore, a detailed analysis of the computational complexity of each solution is reviewed. Furthermore, an extensive set of simulation results is presented. Finally, the main conclusions are summarized, and a set of future aspects and trends that might be interesting for future research in this area is identified. PMID:29671832

[Dentists' workforce in Hungary and international migration].

PubMed

Balázs, Péter

2012-06-01

In Hungary, cross-national migration in dental care was performed rather by patients from abroad instead of the domestic dentists' migration for working abroad. Actually, this tacitly realized and so-called dental tourism experienced two basic changes. The National Medical Tourism Ltd. arranged the First Conference for Development of Dental Tourism on 21 April 2011. Hungary's prime minister addressed the meeting and finally signed an agreement with the organizing Ltd. about governmental financial support for development of dental tourism. On the other hand, Germany and Austria deleted all restrictions against the free cross-national workforce migration since 1 May this year. For understanding and prognosis of dentists' future migration, it is inevitable to collect and analyse relevant data of the previous years. This study is presenting data obtained from January 1, 2006 to December 31, 2010. According to the net outcome, the dentists' human resource system was balanced down to the end of 2010. However, this state is unsure even for the near future, thus preventing the deficit of dentists all necessary measures must be taken to keep up the present level of the domestic dentral service.

Anticipatory Monitoring and Control of Complex Systems using a Fuzzy based Fusion of Support Vector Regressors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miltiadis Alamaniotis; Vivek Agarwal

This paper places itself in the realm of anticipatory systems and envisions monitoring and control methods being capable of making predictions over system critical parameters. Anticipatory systems allow intelligent control of complex systems by predicting their future state. In the current work, an intelligent model aimed at implementing anticipatory monitoring and control in energy industry is presented and tested. More particularly, a set of support vector regressors (SVRs) are trained using both historical and observed data. The trained SVRs are used to predict the future value of the system based on current operational system parameter. The predicted values are thenmore » inputted to a fuzzy logic based module where the values are fused to obtain a single value, i.e., final system output prediction. The methodology is tested on real turbine degradation datasets. The outcome of the approach presented in this paper highlights the superiority over single support vector regressors. In addition, it is shown that appropriate selection of fuzzy sets and fuzzy rules plays an important role in improving system performance.« less

Waste deposit influences on groundwater quality as a tool for waste type and site selection for final storage quality

NASA Astrophysics Data System (ADS)

Arneth, Jan-Dirk; Milde, Gerald; Kerndorff, Helmut; Schleyer, Ruprecht

Leachates from deposits of wastes may, in the long run, adversely influence groundwater quality. Since tipping still constitutes the most important form of waste disposal, strategies must be developed which are capable of protecting groundwater against contamination from leachates. In the first instance such protective measures must provide for a minimization of contamination by setting up optimal barriers. Since it would seem difficult to reach this goal in a forseeable future, the avoidance of substances with a high potential for groundwater hazards has to be attributed much importance. In former times, little attention was given to impermeability or avoidance of substances with a high potential for groundwater hazards contained in wastes. Therefore, results of the investigation of groundwater near abandoned sites can be used to optimize groundwater protection on future tipping sites. In the present study, the results of chemical investigation of groundwater from the vicinity of 92 waste disposal sites in the Federal Republic of Germany are presented and the changes in groundwater quality owing to the penetration of leachates are discussed separately for inorganic and organic contaminants.

X-ray diffraction tomography of polycrystalline materials: present and future (Conference Presentation)

NASA Astrophysics Data System (ADS)

Stock, Stuart R.; Almer, Jonathan D.; Birkedal, Henrik

2016-10-01

Scattered x-radiation can be used for computed tomographic reconstruction of the distribution of crystallographic phases within the interior of specimens, and diffraction patterns can be measured for each volume element (voxel) within a reconstructed slice. This modality has been applied to systems as diverse as mineralized tissues and inorganic composites. Use of high energy x-rays (E < 40 keV) offers advantages including the ability to study volumes deep with specimens and to sample large ranges of reciprocal space, i.e., many reflections. The bases of diffraction tomography are reviewed, and the power of the technique is illustrated by the results obtained for specimens containing: a) different materials (SiC/Al composite), b) different polytypes (calcite/aragonite in a bivalve attachment system); c) mixtures of nanocrystalline and amorphous phases; d) a single phase, but volumes with different lattice parameters (hydroxyapatite, hAp, the mineral in bone and tooth); e) a single phase containing a spatial distribution of crystallographic texture (bone); a single phase with a spatial distribution of strains produced by in situ loading (bone). Finally, challenges and future directions are discussed.

Advancements in the oral delivery of Docetaxel: challenges, current state-of-the-art and future trends

PubMed Central

Sohail, Muhammad Farhan; Rehman, Mubashar; Sarwar, Hafiz Shoaib; Naveed, Sara; Salman, Omer; Bukhari, Nadeem Irfan; Hussain, Irshad; Webster, Thomas J; Shahnaz, Gul

2018-01-01

The oral delivery of cancer chemotherapeutic drugs is challenging due to low bioavailability, gastrointestinal side effects, first-pass metabolism and P-glycoprotein efflux pumps. Thus, chemotherapeutic drugs, including Docetaxel, are administered via an intravenous route, which poses many disadvantages of its own. Recent advances in pharmaceutical research have focused on designing new and efficient drug delivery systems for site-specific targeting, thus leading to improved bioavailability and pharmacokinetics. A decent number of studies have been reported for the safe and effective oral delivery of Docetaxel. These nanocarriers, including liposomes, polymeric nanoparticles, metallic nanoparticles, hybrid nanoparticles, dendrimers and so on, have shown promising results in research papers and clinical trials. The present article comprehensively reviews the research efforts made so far in designing various advancements in the oral delivery of Docetaxel. Different strategies to improve oral bioavailability, prevent first-pass metabolism and inhibition of efflux pumping leading to improved pharmacokinetics and anticancer activity are discussed. The final portion of this review article presents key issues such as safety of nanomaterials, regulatory approval and future trends in nanomedicine research. PMID:29922053

Technologies for Aircraft Noise Reduction

NASA Technical Reports Server (NTRS)

Huff, Dennis L.

2006-01-01

Technologies for aircraft noise reduction have been developed by NASA over the past 15 years through the Advanced Subsonic Technology (AST) Noise Reduction Program and the Quiet Aircraft Technology (QAT) project. This presentation summarizes highlights from these programs and anticipated noise reduction benefits for communities surrounding airports. Historical progress in noise reduction and technologies available for future aircraft/engine development are identified. Technologies address aircraft/engine components including fans, exhaust nozzles, landing gear, and flap systems. New "chevron" nozzles have been developed and implemented on several aircraft in production today that provide significant jet noise reduction. New engines using Ultra-High Bypass (UHB) ratios are projected to provide about 10 EPNdB (Effective Perceived Noise Level in decibels) engine noise reduction relative to the average fleet that was flying in 1997. Audio files are embedded in the presentation that estimate the sound levels for a 35,000 pound thrust engine for takeoff and approach power conditions. The predictions are based on actual model scale data that was obtained by NASA. Finally, conceptual pictures are shown that look toward future aircraft/propulsion systems that might be used to obtain further noise reduction.

Advancements in the oral delivery of Docetaxel: challenges, current state-of-the-art and future trends.

PubMed

Sohail, Muhammad Farhan; Rehman, Mubashar; Sarwar, Hafiz Shoaib; Naveed, Sara; Salman, Omer; Bukhari, Nadeem Irfan; Hussain, Irshad; Webster, Thomas J; Shahnaz, Gul

2018-01-01

The oral delivery of cancer chemotherapeutic drugs is challenging due to low bioavailability, gastrointestinal side effects, first-pass metabolism and P-glycoprotein efflux pumps. Thus, chemotherapeutic drugs, including Docetaxel, are administered via an intravenous route, which poses many disadvantages of its own. Recent advances in pharmaceutical research have focused on designing new and efficient drug delivery systems for site-specific targeting, thus leading to improved bioavailability and pharmacokinetics. A decent number of studies have been reported for the safe and effective oral delivery of Docetaxel. These nanocarriers, including liposomes, polymeric nanoparticles, metallic nanoparticles, hybrid nanoparticles, dendrimers and so on, have shown promising results in research papers and clinical trials. The present article comprehensively reviews the research efforts made so far in designing various advancements in the oral delivery of Docetaxel. Different strategies to improve oral bioavailability, prevent first-pass metabolism and inhibition of efflux pumping leading to improved pharmacokinetics and anticancer activity are discussed. The final portion of this review article presents key issues such as safety of nanomaterials, regulatory approval and future trends in nanomedicine research.

Design and Implementation of a Biomimetic Turtle Hydrofoil for an Autonomous Underwater Vehicle

PubMed Central

Font, Davinia; Tresanchez, Marcel; Siegentahler, Cedric; Pallejà, Tomàs; Teixidó, Mercè; Pradalier, Cedric; Palacin, Jordi

2011-01-01

This paper presents the design and implementation of a turtle hydrofoil for an Autonomous Underwater Vehicle (AUV). The final design of the AUV must have navigation performance like a turtle, which has also been the biomimetic inspiration for the design of the hydrofoil and propulsion system. The hydrofoil design is based on a National Advisory Committee for Aeronautics (NACA) 0014 hydrodynamic profile. During the design stage, four different propulsion systems were compared in terms of propulsion path, compactness, sealing and required power. The final implementation is based on a ball-and-socket mechanism because it is very compact and provides three degrees of freedom (DoF) to the hydrofoil with very few restrictions on the propulsion path. The propulsion obtained with the final implementation of the hydrofoil has been empirically evaluated in a water channel comparing different motion strategies. The results obtained have confirmed that the proposed turtle hydrofoil controlled with a mechanism with three DoF generates can be used in the future implementation of the planned AUV. PMID:22247660

Advanced Transportation System Studies Technical Area 2 (TA-2) Heavy Lift Launch Vehicle Development Contract. Volume 2; Technical Results

NASA Technical Reports Server (NTRS)

1995-01-01

The purpose of the Advanced Transportation System Studies (ATSS) Technical Area 2 (TA-2) Heavy Lift Launch Vehicle Development contract was to provide advanced launch vehicle concept definition and analysis to assist NASA in the identification of future launch vehicle requirements. Contracted analysis activities included vehicle sizing and performance analysis, subsystem concept definition, propulsion subsystem definition (foreign and domestic), ground operations and facilities analysis, and life cycle cost estimation. This document is Volume 2 of the final report for the contract. It provides documentation of selected technical results from various TA-2 analysis activities, including a detailed narrative description of the SSTO concept assessment results, a user's guide for the associated SSTO sizing tools, an SSTO turnaround assessment report, an executive summary of the ground operations assessments performed during the first year of the contract, a configuration-independent vehicle health management system requirements report, a copy of all major TA-2 contract presentations, a copy of the FLO launch vehicle final report, and references to Pratt & Whitney's TA-2 sponsored final reports regarding the identification of Russian main propulsion technologies.

Passive Endwall Treatments for Enhancing Stability

NASA Technical Reports Server (NTRS)

Hathaway, Michael D.

2007-01-01

These lecture notes were presented at the von Karman Institutes lecture series on Advances in Axial Compressor Aerodynamics, May 2006. They provide a fairly extensive overview of what's been learned from numerous investigations of various passive casing endwall technologies that have been proposed for alleviating the stall limiting physics associated with the compressor endwall flow field. The lecture notes are organized to give an appreciation for the inventiveness and understanding of the earliest compressor technologists and to provide a coherent thread of understanding that has arisen out of the early investigations. As such the lecture notes begin with a historical overview of casing treatments from their infancy through the earliest proposed concepts involving blowing, suction and flow recirculation. A summary of lessons learned from these early investigations is provided at the end of this section. The lecture notes then provide a somewhat more in-depth overview of recent advancements in the development of passive casing treatments from the late 1990's through 2006, including advancements in understanding the flow mechanism of circumferential groove casing treatments, and the development of discrete tip injection and self-recirculating casing treatments. At the conclusion of the lecture notes a final summary of lessons learned throughout the history of the development of passive casing treatments is provided. Finally, a list of future needs is given. It is hoped that these lecture notes will be a useful reference for future research endeavors to improve our understanding of the fluid physics of passive casing treatments and how they act to enhance compressor stability, and that they will perhaps provide a springboard for future research activities in this area of interest

How Many Kilonovae Can Be Found in Past, Present, and Future Survey Data Sets?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scolnic, D.; Kessler, R.; Brout, D.

The discovery of a kilonova (KN) associated with the Advanced LIGO (aLIGO)/Virgo event GW170817 opens up new avenues of multi-messenger astrophysics. Here, using realistic simulations, we provide estimates of the number of KNe that could be found in data from past, present, and future surveys without a gravitational-wave trigger. For the simulation, we construct a spectral time-series model based on the DES-GW multi-band light curve from the single known KN event, and we use an average of BNS rates from past studies ofmore » $${10}^{3}\\,{\\mathrm{Gpc}}^{-3}\\,{\\mathrm{yr}}^{-1}$$, consistent with the one event found so far. Examining past and current data sets from transient surveys, the number of KNe we expect to find for ASAS-SN, SDSS, PS1, SNLS, DES, and SMT is between 0 and 0.3. We predict the number of detections per future survey to be 8.3 from ATLAS, 10.6 from ZTF, 5.5/69 from LSST (the Deep Drilling/Wide Fast Deep), and 16.0 from WFIRST. The maximum redshift of KNe discovered for each survey is $z=0.8$ for WFIRST, $z=0.25$ for LSST, and $z=0.04$ for ZTF and ATLAS. This maximum redshift for WFIRST is well beyond the sensitivity of aLIGO and some future GW missions. For the LSST survey, we also provide contamination estimates from Type Ia and core-collapse supernovae: after light curve and template-matching requirements, we estimate a background of just two events. Finally, more broadly, we stress that future transient surveys should consider how to optimize their search strategies to improve their detection efficiency and to consider similar analyses for GW follow-up programs.« less

How Many Kilonovae Can Be Found in Past, Present, and Future Survey Data Sets?

DOE PAGES

Scolnic, D.; Kessler, R.; Brout, D.; ...

2017-12-22

The discovery of a kilonova (KN) associated with the Advanced LIGO (aLIGO)/Virgo event GW170817 opens up new avenues of multi-messenger astrophysics. Here, using realistic simulations, we provide estimates of the number of KNe that could be found in data from past, present, and future surveys without a gravitational-wave trigger. For the simulation, we construct a spectral time-series model based on the DES-GW multi-band light curve from the single known KN event, and we use an average of BNS rates from past studies ofmore » $${10}^{3}\\,{\\mathrm{Gpc}}^{-3}\\,{\\mathrm{yr}}^{-1}$$, consistent with the one event found so far. Examining past and current data sets from transient surveys, the number of KNe we expect to find for ASAS-SN, SDSS, PS1, SNLS, DES, and SMT is between 0 and 0.3. We predict the number of detections per future survey to be 8.3 from ATLAS, 10.6 from ZTF, 5.5/69 from LSST (the Deep Drilling/Wide Fast Deep), and 16.0 from WFIRST. The maximum redshift of KNe discovered for each survey is $z=0.8$ for WFIRST, $z=0.25$ for LSST, and $z=0.04$ for ZTF and ATLAS. This maximum redshift for WFIRST is well beyond the sensitivity of aLIGO and some future GW missions. For the LSST survey, we also provide contamination estimates from Type Ia and core-collapse supernovae: after light curve and template-matching requirements, we estimate a background of just two events. Finally, more broadly, we stress that future transient surveys should consider how to optimize their search strategies to improve their detection efficiency and to consider similar analyses for GW follow-up programs.« less

A Futures Orientation in the Australian Curriculum: Current Levels of Teacher Interest, Activity and Support in Western Australia

ERIC Educational Resources Information Center

Paynter, Mark; Bruce, Neville

2014-01-01

The soon to be implemented Australian Curriculum aims to integrate a futures orientation across subject areas. Guidelines and support for this specific initiative are being finalized. Only a little is known about the current teaching of a futures orientation or of secondary teacher interest, understanding and support for this important but…

Applications of biomechanics for prevention of work-related musculoskeletal disorders.

PubMed

Garg, Arun; Kapellusch, Jay M

2009-01-01

This paper summarises applications of biomechanical principles and models in industry to control musculoskeletal disorders of the low back and upper extremity. Applications of 2-D and 3-D biomechanical models to estimate compressive force on the low back, the strength requirements of jobs, application of guidelines for overhead work and application of strain index and threshold limit value to address distal upper extremity musculoskeletal disorders are presented. Several case studies applied in the railroad industry, manufacturing, healthcare and warehousing are presented. Finally, future developments needed for improved biomechanical applications in industry are discussed. The information presented will be of value to practising ergonomists to recognise how biomechanics has played a significant role in identifying causes of musculoskeletal disorders and controlling them in the workplace. In particular, the information presented will help practising ergonomists with how physical stresses can be objectively quantified.

Applied Computational Fluid Dynamics at NASA Ames Research Center

NASA Technical Reports Server (NTRS)

Holst, Terry L.; Kwak, Dochan (Technical Monitor)

1994-01-01

The field of Computational Fluid Dynamics (CFD) has advanced to the point where it can now be used for many applications in fluid mechanics research and aerospace vehicle design. A few applications being explored at NASA Ames Research Center will be presented and discussed. The examples presented will range in speed from hypersonic to low speed incompressible flow applications. Most of the results will be from numerical solutions of the Navier-Stokes or Euler equations in three space dimensions for general geometry applications. Computational results will be used to highlight the presentation as appropriate. Advances in computational facilities including those associated with NASA's CAS (Computational Aerosciences) Project of the Federal HPCC (High Performance Computing and Communications) Program will be discussed. Finally, opportunities for future research will be presented and discussed. All material will be taken from non-sensitive, previously-published and widely-disseminated work.

Development of an Active Twist Rotor for Wind: Tunnel Testing (NLPN97-310

NASA Technical Reports Server (NTRS)

Cesnik, Carlos E. S.; Shin, SangJoon; Hagood, Nesbitt W., IV

1998-01-01

The development of the Active Twist Rotor prototype blade for hub vibration and noise reduction studies is presented in this report. Details of the modeling, design, and manufacturing are explored. The rotor blade is integrally twisted by direct strain actuation. This is accomplished by distributing embedded piezoelectric fiber composites along the span of the blade. The development of the analysis framework for this type of active blade is presented. The requirements for the prototype blade, along with the final design results are also presented. A detail discussion on the manufacturing aspects of the prototype blade is described. Experimental structural characteristics of the prototype blade compare well with design goals, and preliminary bench actuation tests show lower performance than originally predicted. Electrical difficulties with the actuators are also discussed. The presented prototype blade is leading to a complete fully articulated four-blade active twist rotor system for future wind tunnel tests.

Radiation budget measurement/model interface

NASA Technical Reports Server (NTRS)

Vonderhaar, T. H.; Ciesielski, P.; Randel, D.; Stevens, D.

1983-01-01

This final report includes research results from the period February, 1981 through November, 1982. Two new results combine to form the final portion of this work. They are the work by Hanna (1982) and Stevens to successfully test and demonstrate a low-order spectral climate model and the work by Ciesielski et al. (1983) to combine and test the new radiation budget results from NIMBUS-7 with earlier satellite measurements. Together, the two related activities set the stage for future research on radiation budget measurement/model interfacing. Such combination of results will lead to new applications of satellite data to climate problems. The objectives of this research under the present contract are therefore satisfied. Additional research reported herein includes the compilation and documentation of the radiation budget data set a Colorado State University and the definition of climate-related experiments suggested after lengthy analysis of the satellite radiation budget experiments.

Triple top signal as a probe of charged Higgs in a 2HDM

NASA Astrophysics Data System (ADS)

Patrick, Riley; Sharma, Pankaj; Williams, Anthony G.

2018-05-01

Within the framework of the type-II Two Higgs Doublet Model (2HDM-II) we study the production of three top quarks at the Large Hadron Collider (LHC). In the Standard Model the production cross section of three tops is low (≈3 fb), while it is expected to be significant in the 2HDM-II for reasonable choices of the parameters. We study the production of a charged Higgs in association with a top quark, followed by the decays H± →W± A and A → t t bar . We undertake a full detector simulation of the signal, and use simple conservative cuts, focussing on the final states that contain three or more leptons, and exactly one same sign di-lepton pair. Finally, we present the exclusion bounds dependent on charged Higgs and pseudoscalar Higgs masses expected in the near future at the 14 TeV LHC.

Energy Efficient Engine Flight Propulsion System Preliminary Analysis and Design Report

NASA Technical Reports Server (NTRS)

Bisset, J. W.; Howe, D. C.

1983-01-01

The final design and analysis of the flight propulsion system is presented. This system is the conceptual study engine defined to meet the performance, economic and environmental goals established for the Energy Efficient Engine Program. The design effort included a final definition of the engine, major components, internal subsystems, and nacelle. Various analytical representations and results from component technology programs are used to verify aerodynamic and structural design concepts and to predict performance. Specific design goals and specifications, reflecting future commercial aircraft propulsion system requirements for the mid-1980's, are detailed by NASA and used as guidelines during engine definition. Information is also included which details salient results from a separate study to define a turbofan propulsion system, known as the maximum efficiency engine, which reoptimized the advanced fuel saving technologies for improved fuel economy and direct operating costs relative to the flight propulsion system.

Capabilities and Present Status of The Sicaya Radio Telescope in Peru

NASA Astrophysics Data System (ADS)

Ishitsuka, J. K.; Kobayashi, H.; Miyoshi, M.

2017-07-01

The private telephone company, Telefónica del Perú, stopped operations of the Sicaya Intelsat Station in 2000, we knew that they were looking for some institution to own the Station in 2002 and begun conversations. Finally in 2008, the whole communications station with a 32-meters parabolic antenna was donated to the Geophysical Institute of Peru. Many things have happened since that, but finally we are almost ready to have a radio telescope. National Astronomical Observatory of Japan contributed enormously to set up the radio telescope. Initially as a single dish radio telescope, it will observe methanol maser at 6.7 GHz of young stellar objects. In the near future, equipping for VLBI observations is in the scope. Sicaya is situated on the central part of Peru at 3,370 meters of altitude and the weather is benign for radio astronomical observations, also humidity is low and allows have radio telescopes free of rust.

(abstract) An Assessment of Electric Propulsion Research, Development, and Application in the United States

NASA Technical Reports Server (NTRS)

Stephenson, R. Rhoads

1995-01-01

This paper will discuss the development of Electric Propulsion technology in the U.S. from the 1960's to the present. It will summarize the various activities related to arcjets, resistojets, pulsed plasma thrustors, magneto-plasma-dynamic thrustors, ion engines, and more recently the evaluation of Hall effect thrustors of the SPT or Anode Layer type developed in Russia. Also, demonstration test flight and actual mission applications will be summarized. Finally, the future application of electric propulsion to near-term commercial communications satellites and planetary missions will be projected. This history is rich in diversity, and has involved a succession of types of thrustors, propellants, and electric power sources. With the recent use of arcjets on commercial communication satellites and the flight tests of ion engines for this application, it appears that electric propulsion is finally on the verge of wide spread application.

Optical Fiber Sensors Based on Fiber Ring Laser Demodulation Technology

PubMed Central

Xie, Wen-Ge; Wang, Peng-Zhao; Wang, Jian-Zhang

2018-01-01

A review for optical fiber sensors based on fiber ring laser (FRL) demodulation technology is presented. The review focuses on the principles, main structures, and the sensing performances of different kinds of optical fiber sensors based on FRLs. First of all, the theory background of the sensors has been discussed. Secondly, four different types of sensors are described and compared, which includes Mach–Zehnder interferometer (MZI) typed sensors, Fabry–Perot interferometer (FPI) typed sensors, Sagnac typed sensors, and fiber Bragg grating (FBG) typed sensors. Typical studies and main properties of each type of sensors are presented. Thirdly, a comparison of different types of sensors are made. Finally, the existing problems and future research directions are pointed out and analyzed. PMID:29419745

Clinical governance in pre-hospital care.

PubMed Central

Robertson-Steel, I; Edwards, S; Gough, M

2001-01-01

This article seeks to discover and recognize the importance of clinical governance within a new and emerging quality National Health Service (NHS) system. It evaluates the present state of prehospital care and recommends how change, via clinical governance, can ensure a paradigm shift from its currently fragmented state to a seamless ongoing patient care episode. Furthermore, it identifies the drivers of a quality revolution, examines the monitoring and supervision of quality care, and evaluates the role of evidence-based practice. A frank and open view of immediate care doctors is presented, with recommendations to improve the quality of skill delivery and reduce the disparity that exists. Finally, it reviews the current problems with pre-hospital care and projects a future course for quality and patient care excellence. PMID:11383428

High Power K Sub a -band Transmitter for Planetary Radar and Spacecraft Uplink

NASA Technical Reports Server (NTRS)

Bhanji, A. M.; Hoppe, D. J.; Hartop, R. W.; Stone, E. W.; Imbriale, W. A.; Stone, D.; Caplan, M.

1984-01-01

A proposed conceptual design of a 400 kW continuous wave (CW)K sub a band transmitter and associated microwave components to be used for planetary radar and serve as a prototype for future spacecraft uplinks is discussed. System requirements for such a transmitter are presented. Performance of the proposed high-power millimeter wave tube, the gyroklystron is discussed. Parameters of the proposed power amplifier, beam supply, and monitor and control devices are also presented. Microwave transmission line components consisting of signal monitoring devices, signal filtering devices, and an overmoded corrugated feed are discussed. Finally, an assessment of the state of the art technology to meet the system requirements is given and possible areas of difficulty are summarized.

Structural evaluation of a DTHR bundle divertor particle collector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prevenslik, T.V.

1980-09-01

The purpose of this report is to present a structural evaluation of the current bundle divertor particle collector BDPC design under a peak heat flux in relation to criteria that protect against coolant leakage into the plasma over replacement schedules planned during DTHR operation. In addition, an assessment of the BDPC structural integrity at higher heat fluxes is presented. Further, recommendations for modifications in the current BDPC design that would improve design reliability to be considered in future design studies are described. Finally, experimental test programs directed to establishing materials data necessary in providing greater confidence in subsequent structural evaluationsmore » of BDPC designs in relation to coolant leakage over planned replacement schedules are identified.« less

A Review of Recent Advances in Research on PM2.5 in China

PubMed Central

Zou, Jiale; Yang, Wei; Li, Chun-Qing

2018-01-01

PM2.5 pollution has become a severe problem in China due to rapid industrialization and high energy consumption. It can cause increases in the incidence of various respiratory diseases and resident mortality rates, as well as increase in the energy consumption in heating, ventilation, and air conditioning (HVAC) systems due to the need for air purification. This paper reviews and studies the sources of indoor and outdoor PM2.5, the impact of PM2.5 pollution on atmospheric visibility, occupational health, and occupants’ behaviors. This paper also presents current pollution status in China, the relationship between indoor and outdoor PM2.5, and control of indoor PM2.5, and finally presents analysis and suggestions for future research. PMID:29498704

National Transonic Facility Wall Pressure Calibration Using Modern Design of Experiments (Invited)

NASA Technical Reports Server (NTRS)

Underwood, Pamela J.; Everhart, Joel L.; DeLoach, Richard

2001-01-01

The Modern Design of Experiments (MDOE) has been applied to wind tunnel testing at NASA Langley Research Center for several years. At Langley, MDOE has proven to be a useful and robust approach to aerodynamic testing that yields significant reductions in the cost and duration of experiments while still providing for the highest quality research results. This paper extends its application to include empty tunnel wall pressure calibrations. These calibrations are performed in support of wall interference corrections. This paper will present the experimental objectives, and the theoretical design process. To validate the tunnel-empty-calibration experiment design, preliminary response surface models calculated from previously acquired data are also presented. Finally, lessons learned and future wall interference applications of MDOE are discussed.

Optical Fiber Sensors Based on Fiber Ring Laser Demodulation Technology.

PubMed

Xie, Wen-Ge; Zhang, Ya-Nan; Wang, Peng-Zhao; Wang, Jian-Zhang

2018-02-08

A review for optical fiber sensors based on fiber ring laser (FRL) demodulation technology is presented. The review focuses on the principles, main structures, and the sensing performances of different kinds of optical fiber sensors based on FRLs. First of all, the theory background of the sensors has been discussed. Secondly, four different types of sensors are described and compared, which includes Mach-Zehnder interferometer (MZI) typed sensors, Fabry-Perot interferometer (FPI) typed sensors, Sagnac typed sensors, and fiber Bragg grating (FBG) typed sensors. Typical studies and main properties of each type of sensors are presented. Thirdly, a comparison of different types of sensors are made. Finally, the existing problems and future research directions are pointed out and analyzed.

Perception of effort in Exercise Science: Definition, measurement and perspectives.

PubMed

Pageaux, Benjamin

2016-11-01

Perception of effort, also known as perceived exertion or sense of effort, can be described as a cognitive feeling of work associated with voluntary actions. The aim of the present review is to provide an overview of what is perception of effort in Exercise Science. Due to the addition of sensations other than effort in its definition, the neurophysiology of perceived exertion remains poorly understood. As humans have the ability to dissociate effort from other sensations related to physical exercise, the need to use a narrower definition is emphasised. Consequently, a definition and some brief guidelines for its measurement are provided. Finally, an overview of the models present in the literature aiming to explain its neurophysiology, and some perspectives for future research are offered.

Design process of a photonics network for military platforms

NASA Astrophysics Data System (ADS)

Nelson, George F.; Rao, Nagarajan M.; Krawczak, John A.; Stevens, Rick C.

1999-02-01

Technology development in photonics is rapidly progressing. The concept of a Unified Network will provide re- configurable network access to platform sensors, Vehicle Management Systems, Stores and avionics. The re-configurable taps into the network will accommodate present interface standards and provide scaleability for the insertion of future interfaces. Significant to this development is the design and test of the Optical Backplane Interconnect System funded by Naval Air Systems Command and developed by Lockheed Martin Tactical Defense Systems - Eagan. OBIS results in the merging of the electrical backplane and the optical backplane, with interconnect fabric and card edge connectors finally providing adequate electrical and optical card access. Presently OBIS will support 1.2 Gb/s per fiber over multiples of 12 fibers per ribbon cable.

Sleep disorders and chronic kidney disease.

PubMed

Maung, Stephanie C; El Sara, Ammar; Chapman, Cherylle; Cohen, Danielle; Cukor, Daniel

2016-05-06

Sleep disorders have a profound and well-documented impact on overall health and quality of life in the general population. In patients with chronic disease, sleep disorders are more prevalent, with an additional morbidity and mortality burden. The complex and dynamic relationship between sleep disorders and chronic kidney disease (CKD) remain relatively little investigated. This article presents an overview of sleep disorders in patients with CKD, with emphasis on relevant pathophysiologic underpinnings and clinical presentations. Evidence-based interventions will be discussed, in the context of individual sleep disorders, namely sleep apnea, insomnia, restless leg syndrome and excessive daytime sleepiness. Limitations of the current knowledge as well as future research directions will be highlighted, with a final discussion of different conceptual frameworks of the relationship between sleep disorders and CKD.

A Review of Recent Advances in Research on PM2.5 in China.

PubMed

Lin, Yaolin; Zou, Jiale; Yang, Wei; Li, Chun-Qing

2018-03-02

PM 2.5 pollution has become a severe problem in China due to rapid industrialization and high energy consumption. It can cause increases in the incidence of various respiratory diseases and resident mortality rates, as well as increase in the energy consumption in heating, ventilation, and air conditioning (HVAC) systems due to the need for air purification. This paper reviews and studies the sources of indoor and outdoor PM 2.5 , the impact of PM 2.5 pollution on atmospheric visibility, occupational health, and occupants' behaviors. This paper also presents current pollution status in China, the relationship between indoor and outdoor PM 2.5 , and control of indoor PM 2.5 , and finally presents analysis and suggestions for future research.

An Independent Scientific Assessment of Well Stimulation in California Volume II

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jane C.S. Long; Laura C. Feinstein; Corinne E. Bachmann

This study is issued in three volumes. Volume I, issued in January 2015, describes how well stimulation technologies work, how and where operators deploy these technologies for oil and gas production in California, and where they might enable production in the future. Volume II, the present volume, discusses how well stimulation could affect water, atmosphere, seismic activity, wildlife and vegetation, and human health. Volume II reviews available data, and identifies knowledge gaps and alternative practices that could avoid or mitigate these possible impacts. Volume III, also issued in July 2015, presents case studies that assess environmental issues and qualitative risksmore » for specific geographic regions. A final Summary Report summarizes key findings, conclusions and recommendations of all three volumes.« less

Lithium-Air and ionic Liquids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kellar, Michael

2015-09-01

The final portion of this project was accomplished at Sandia National Labs, Livermore, with the overall goal being to optimize lithium-air cells with an ionic liquid electrolyte. Both of these are potential future routes for lithium-ion technology. Lithiumair presents the advantage of higher gravimetric energy density, and ionic liquids present the advantage of greater hydrophobicity and much lower volatility, along with a larger window of electrochemical stability. Ionic liquids however have several drawbacks for the battery industry. Currently they are not as cost effective as many organic solvents. Additionally, because of the added viscosity of ionic interactions compared to themore » typical dipole interactions of a solvent, the ionic conductivity is lower than for common organic solvents.« less

First Experiences Using XACML for Access Control in Distributed Systems

NASA Technical Reports Server (NTRS)

Lorch, Marcus; Proctor, Seth; Lepro, Rebekah; Kafura, Dennis; Shah, Sumit

2003-01-01

Authorization systems today are increasingly complex. They span domains of administration, rely on many different authentication sources, and manage permissions that can be as complex as the system itself. Worse still, while there are many standards that define authentication mechanisms, the standards that address authorization are less well defined and tend to work only within homogeneous systems. This paper presents XACML, a standard access control language, as one component of a distributed and inter-operable authorization framework. Several emerging systems which incorporate XACML are discussed. These discussions illustrate how authorization can be deployed in distributed, decentralized systems. Finally, some new and future topics are presented to show where this work is heading and how it will help connect the general components of an authorization system.

Wildlife habitat connectivity in the changing climate of New York's Hudson Valley.

PubMed

Howard, Timothy G; Schlesinger, Matthew D

2013-09-01

Maintaining and restoring connectivity are key adaptation strategies for biodiversity conservation under climate change. We present a novel combination of species distribution and connectivity modeling using current and future climate regimes to prioritize connections among populations of 26 rare species in New York's Hudson Valley. We modeled patches for each species for each time period and modeled potential connections among habitat patches by finding the least-cost path for every patch-to-patch connection. Finally, we aggregated these patches and paths to the tax parcel, commonly the primary unit of conservation action. Under future climate regimes, suitable habitat was predicted to contract or appear upslope and farther north. On average, predicted patches were nine times smaller and paths were twice as long under future climate. Parcels within the Hudson Highlands, Shawangunk Ridge, Catskill Mountains, and Harlem Valley had high species overlap, with areas upslope and northward increasing in importance over time. We envision that land managers and conservation planners can use these results to help prioritize parcel-level conservation and management and thus support biodiversity adaptation to climate change. © 2013 New York Academy of Sciences.

The Italian economic crisis and its impact on nursing services and education: hard and challenging times.

PubMed

Bortoluzzi, Guido; Palese, Alvisa

2010-07-01

Three levels of impact are reported and discussed in this commentary: the 'macro' level, which corresponds to policy(ies); the 'meso' level, which corresponds to nursing services and nursing education; and the 'micro' level, which deals with clinical practice and education, where interactions between patients and nurses and/or students take place. The Italian economy is showing some signs of recovery after the worst economic crisis of past decades. However, these signs are still quite weak and insufficient to declare that the country is finally coming out of it. Several negative impacts of the economic crisis on nursing services and nursing education are documented. Reports have started to document initial signs of the economical crisis impact on patients too. Present and future issues related to nursing services, education and clinical practice are commented both from national data and from nurses' daily perceptions. The Italian economic crisis will leave a heavy burden on the shoulders of future generations. Nurses' leaders are coping with these challenges, innovating the nursing system and preparing a sustainable future for generations of patients and nurses.

A novel integrated approach for the hazardous radioactive dust source terms estimation in future nuclear fusion power plants.

PubMed

Poggi, L A; Malizia, A; Ciparisse, J F; Gaudio, P

2016-10-01

An open issue still under investigation by several international entities working on the safety and security field for the foreseen nuclear fusion reactors is the estimation of source terms that are a hazard for the operators and public, and for the machine itself in terms of efficiency and integrity in case of severe accident scenarios. Source term estimation is a crucial key safety issue to be addressed in the future reactors safety assessments, and the estimates available at the time are not sufficiently satisfactory. The lack of neutronic data along with the insufficiently accurate methodologies used until now, calls for an integrated methodology for source term estimation that can provide predictions with an adequate accuracy. This work proposes a complete methodology to estimate dust source terms starting from a broad information gathering. The wide number of parameters that can influence dust source term production is reduced with statistical tools using a combination of screening, sensitivity analysis, and uncertainty analysis. Finally, a preliminary and simplified methodology for dust source term production prediction for future devices is presented.

Narrative synthesis of equine-assisted psychotherapy literature: Current knowledge and future research directions.

PubMed

Lee, Ping-Tzu; Dakin, Emily; McLure, Merinda

2016-05-01

Equine-assisted psychotherapy (EAP) is an innovative emerging approach to mental health treatment. This narrative synthesis explores the current state of knowledge and areas for future research in EAP. Specifically reviewed are qualitative and quantitative empirical studies, including both articles published in peer-reviewed journals and research presented in theses and dissertations. We selected 24 studies for final inclusion in this study, dating between 2005 and 2013, and including the first EAP empirical research completed in 2005. Four of these studies are peer-reviewed journal articles, while 20 are master's theses or doctoral dissertations. The reviewed qualitative research provides initial evidence for the value of EAP for enhancing adolescents' communication and relationship skills. The reviewed experimental and quasi-experimental research provides initial evidence for the value of EAP for enhancing children's and adolescents' emotional, social and behavioural functioning. Yet, conclusions about the effectiveness of EAP must still be considered preliminary due to various methodological limitations in the reviewed research. The narrative review describes these methodological limitations and concludes with recommendations for future research. © 2015 John Wiley & Sons Ltd.

Three decades of Cognition & Emotion: A brief review of past highlights and future prospects.

PubMed

Rothermund, Klaus; Koole, Sander L

2018-02-01

Over the past three decades, Cognition & Emotion has been one of the world's leading outlets for emotion research. In this article, we review past highlights of and future prospects for the journal. Our tour of history covers three periods: The first period, from 1987 to 1999, was a pioneering era in which cognitive theories began to be applied to the scientific analysis of emotion. The second period, from 2000 to 2007, was characterised by a sharp increase in the number of empirical research papers, a lot of which were concerned with automatic processing biases and their implications for clinical psychology. During the third period, from 2008 to 2017, a new focus emerged on self-regulatory processes and their implications for emotion. We then turn to the present profile of Cognition & Emotion and introduce our new editorial team. Finally, we consider how the journal's future success can be continued and increased by a) providing authors with fast and high-quality feedback; b) offering attractive publication formats, including the newly introduced Registered Reports for pre-registered studies; and c) consolidating key methodological paradigms with reproducible findings.

Sea-level rise caused by climate change and its implications for society.

PubMed

Mimura, Nobuo

2013-01-01

Sea-level rise is a major effect of climate change. It has drawn international attention, because higher sea levels in the future would cause serious impacts in various parts of the world. There are questions associated with sea-level rise which science needs to answer. To what extent did climate change contribute to sea-level rise in the past? How much will global mean sea level increase in the future? How serious are the impacts of the anticipated sea-level rise likely to be, and can human society respond to them? This paper aims to answer these questions through a comprehensive review of the relevant literature. First, the present status of observed sea-level rise, analyses of its causes, and future projections are summarized. Then the impacts are examined along with other consequences of climate change, from both global and Japanese perspectives. Finally, responses to adverse impacts will be discussed in order to clarify the implications of the sea-level rise issue for human society.(Communicated by Kiyoshi HORIKAWA, M.J.A.).

Age and impulsive behavior in drug addiction: A review of past research and future directions.

PubMed

Argyriou, Evangelia; Um, Miji; Carron, Claire; Cyders, Melissa A

2018-01-01

Impulsive behavior is implicated in the initiation, maintenance, and relapse of drug-seeking behaviors involved in drug addiction. Research shows that changes in impulsive behavior across the lifespan contribute to drug use and addiction. The goal of this review is to examine existing research on the relationship between impulsive behavior and drug use across the lifespan and to recommend directions for future research. Three domains of impulsive behavior are explored in this review: impulsive behavior-related personality traits, delay discounting, and prepotent response inhibition. First, we present previous research on these three domains of impulsive behavior and drug use across developmental stages. Then, we discuss how changes in impulsive behavior across the lifespan are implicated in the progression of drug use and addiction. Finally, we discuss the relatively limited attention given to middle-to-older adults in the current literature, consider the validity of the measures used to assess impulsive behavior in middle-to-older adulthood, and suggest recommendations for future research. Copyright © 2017 Elsevier Inc. All rights reserved.

A Post-Final Assignment for the Methods Course: Providing an Incentive to Professional Growth for Future Teachers.

ERIC Educational Resources Information Center

Bentley, Michael L.

This paper describes J. Rosengren's post-final assignment and M. Harmin's truth signs activity that were incorporated into a secondary science methods course for preservice teachers. The strength of the post-final assignment is that it is a strategy for extending student learning past the end of a course and even beyond the initial teaching…

Research and development of a heat-pump water heater. Volume 2. R and D task reports

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dunning, R.L.; Amthor, F.R.; Doyle, E.J.

1978-08-01

The heat pump water heater is a device that works much like a window air conditioner except that heat from the home is pumped into a water tank rather than to the outdoors. The objective established for the device is to operate with a Coefficient of Performance (COP) of 3 or, an input of one unit of electric energy would create three units of heat energy in the form of hot water. With such a COP, the device would use only one-third the energy and at one-third the cost of a standard resistance water heater. This Volume 2 contains themore » final reports of the three major tasks performed in Phase I. In Task 2, a market study identifies the future market and selects an initial target market and channel of distribution, all based on an analysis of the parameters affecting feasibility of the device and the factors that will affect its market acceptance. In the Task 3 report, the results of a design and test program to arrive at final designs of heat pumps for both new water heaters and for retrofitting existing water heaters are presented. In the Task 4 report, a plan for an extensive field demonstration involving use in actual homes is presented. Volume 1 contains a final summary report of the information in Volume 2.« less

Recent Advances of Solution-Processed Metal Oxide Thin-Film Transistors.

PubMed

Xu, Wangying; Li, Hao; Xu, Jian-Bin; Wang, Lei

2018-03-06

Solution-processed metal oxide thin-film transistors (TFTs) are considered as one of the most promising transistor technologies for future large-area flexible electronics. This review surveys the recent advances in solution-based oxide TFTs, including n-type oxide semiconductors, oxide dielectrics and p-type oxide semiconductors. Firstly, we provide an introduction on oxide TFTs and the TFT configurations and operating principles. Secondly, we present the recent progress in solution-processed n-type transistors, with a special focus on low-temperature and large-area solution processed approaches as well as novel non-display applications. Thirdly, we give a detailed analysis of the state-of-the-art solution-processed oxide dielectrics for low-voltage electronics. Fourthly, we discuss the recent progress in solution-based p-type oxide semiconductors, which will enable the highly desirable future low-cost large-area complementary circuits. Finally, we draw the conclusions and outline the perspectives over the research field.

Normal modes of the world's oceans: A numerical investigation using Proudman functions

NASA Technical Reports Server (NTRS)

Sanchez, Braulio V.; Morrow, Dennis

1993-01-01

The numerical modeling of the normal modes of the global oceans is addressed. The results of such modeling could be expected to serve as a guide in the analysis of observations and measurements intended to detect these modes. The numerical computation of normal modes of the global oceans is a field in which several investigations have obtained results during the past 15 years. The results seem to be model-dependent to an unsatisfactory extent. Some modeling areas, such as higher resolution of the bathymetry, inclusion of self-attraction and loading, the role of the Arctic Ocean, and systematic testing by means of diagnostic models are addressed. The results show that the present state of the art is such that a final solution to the normal mode problem still lies in the future. The numerical experiments show where some of the difficulties are and give some insight as to how to proceed in the future.

Mathematical Models for Immunology: Current State of the Art and Future Research Directions.

PubMed

Eftimie, Raluca; Gillard, Joseph J; Cantrell, Doreen A

2016-10-01

The advances in genetics and biochemistry that have taken place over the last 10 years led to significant advances in experimental and clinical immunology. In turn, this has led to the development of new mathematical models to investigate qualitatively and quantitatively various open questions in immunology. In this study we present a review of some research areas in mathematical immunology that evolved over the last 10 years. To this end, we take a step-by-step approach in discussing a range of models derived to study the dynamics of both the innate and immune responses at the molecular, cellular and tissue scales. To emphasise the use of mathematics in modelling in this area, we also review some of the mathematical tools used to investigate these models. Finally, we discuss some future trends in both experimental immunology and mathematical immunology for the upcoming years.

[Future of laparoscopy in colorectal cancer surgery].

PubMed

Grotowski, Maciej

2004-07-01

Laparoscopic surgery has been associated with less postoperative pain, an early return of bowel function, a shorter period of hospitalization and disability, and better cosmetic results. In the past decade laparoscopic techniques are increasingly being applied to colorectal surgical procedures. Diagnostic laparoscopy, the creation of stomas, and limited resections are becoming reasonable indications for benign diseases. However, the application of laparoscopic techniques to the curative resection of colorectal cancer is still controversial, owing to reports of cancer recurrence at the port site wounds. Port-site recurrence remains a leading concern regarding the widespread acceptance of laparoscopic resection for colorectal carcinoma. The last reports has presented that with careful technique, training and experience wound recurrences are rarely seen, suggesting that this phenomenon is primarily technique and advanced cancer stages related. The final results of the large randomized prospective studies may well determine the role of laparoscopy for colorectal cancer in the near future.

"Letting myself go forward past wrongs": How regulatory modes affect self-forgiveness

PubMed Central

Giannini, Anna Maria; Higgins, E. Tory; Kruglanski, Arie W.

2018-01-01

The present research addresses the question of whether regulatory-mode orientations affect self-forgiveness. We expected that people with a strong locomotion orientation would be more inclined to self-forgiveness because of their tendencies toward movement and change, which focus them on the future, whereas people with a strong assessment orientation would refrain from self-forgiveness due to their evaluative tendencies which focus them on the past. These hypotheses were supported by the results in four studies that tested the relation between regulatory modes and self-forgiveness by measuring (Studies 1, 3 and 4) and manipulating (Study 2) regulatory-mode-orientations. Finally, in Study 4 we examined more closely our hypothesis that the relation between self-forgiveness and regulatory modes is mediated by past and future temporal foci. The implications of the results for regulatory mode theory are also discussed. PMID:29529065

Identification and impact of discoverers in online social systems

PubMed Central

Medo, Matúš; Mariani, Manuel S.; Zeng, An; Zhang, Yi-Cheng

2016-01-01

Understanding the behavior of users in online systems is of essential importance for sociology, system design, e-commerce, and beyond. Most existing models assume that individuals in diverse systems, ranging from social networks to e-commerce platforms, tend to what is already popular. We propose a statistical time-aware framework to identify the users who differ from the usual behavior by being repeatedly and persistently among the first to collect the items that later become hugely popular. Since these users effectively discover future hits, we refer them as discoverers. We use the proposed framework to demonstrate that discoverers are present in a wide range of real systems. Once identified, discoverers can be used to predict the future success of new items. We finally introduce a simple network model which reproduces the discovery patterns observed in the real data. Our results open the door to quantitative study of detailed temporal patterns in social systems. PMID:27687588

Vegetation projections for Wind Cave National Park with three future climate scenarios: Final report in completion of Task Agreement J8W07100052

USGS Publications Warehouse

King, David A.; Bachelet, Dominique M.; Symstad, Amy J.

2013-01-01

Since the initial application of MC1 to a small portion of WICA (Bachelet et al. 2000), the model has been altered to improve model performance with the inclusion of dynamic fire. Applying this improved version to WICA required substantial recalibration, during which we have made a number of improvements to MC1 that will be incorporated as permanent changes. In this report we document these changes and our calibration procedure following a brief overview of the model. We compare the projections of current vegetation to the current state of the park and present projections of vegetation dynamics under future climates downscaled from three GCMs selected to represent the existing range in available GCM projections. In doing so, we examine the consequences of different management options regarding fire and grazing, major aspects of biotic management at Wind Cave.

Water, Sanitation and Hygiene in Haiti: Past, Present, and Future

PubMed Central

Gelting, Richard; Bliss, Katherine; Patrick, Molly; Lockhart, Gabriella; Handzel, Thomas

2013-01-01

Haiti has the lowest rates of access to improved water and sanitation infrastructure in the western hemisphere. This situation was likely exacerbated by the earthquake in 2010 and also contributed to the rapid spread of the cholera epidemic that started later that same year. This report examines the history of the water, sanitation, and hygiene (WASH) sector in Haiti, considering some factors that have influenced WASH conditions in the country. We then discuss the situation sine the earthquake and subsequent cholera epidemic, and the responses to those events. Finally, drawing on Haiti's National Plan of Action for the Elimination of Cholera in Haiti 2013–2022, we suggest some actions that could help bring about long-term WASH improvements for the future. Because the current WASH situation has evolved over decades of limited attention and resources, it will take a long-term, sustained effort to improve the situation. PMID:24106193

Vitreous Substitutes: The Present and the Future

PubMed Central

Caprani, Simona Maria; Airaghi, Giulia; Bartalena, Luigi; Testa, Francesco; Mariotti, Cesare; Porta, Giovanni; Simonelli, Francesca

2014-01-01

Vitreoretinal surgery has advanced in numerous directions during recent years. The removal of the vitreous body is one of the main characteristics of this surgical procedure. Several molecules have been tested in the past to fill the vitreous cavity and to mimic its functions. We here review the currently available vitreous substitutes, focusing on their molecular properties and functions, together with their adverse effects. Afterwards we describe the characteristics of the ideal vitreous substitute. The challenges facing every ophthalmology researcher are to reach a long-term intraocular permanence of vitreous substitute with total inertness of the molecule injected and the control of inflammatory reactions. We report new polymers with gelification characteristics and smart hydrogels representing the future of vitreoretinal surgery. Finally, we describe the current studies on vitreous regeneration and cell cultures to create new intraocular gels with optimal biocompatibility and rheological properties. PMID:24877085

Hybrid organic semiconductor lasers for bio-molecular sensing.

PubMed

Haughey, Anne-Marie; Foucher, Caroline; Guilhabert, Benoit; Kanibolotsky, Alexander L; Skabara, Peter J; Burley, Glenn; Dawson, Martin D; Laurand, Nicolas

2014-01-01

Bio-functionalised luminescent organic semiconductors are attractive for biophotonics because they can act as efficient laser materials while simultaneously interacting with molecules. In this paper, we present and discuss a laser biosensor platform that utilises a gain layer made of such an organic semiconductor material. The simple structure of the sensor and its operation principle are described. Nanolayer detection is shown experimentally and analysed theoretically in order to assess the potential and the limits of the biosensor. The advantage conferred by the organic semiconductor is explained, and comparisons to laser sensors using alternative dye-doped materials are made. Specific biomolecular sensing is demonstrated, and routes to functionalisation with nucleic acid probes, and future developments opened up by this achievement, are highlighted. Finally, attractive formats for sensing applications are mentioned, as well as colloidal quantum dots, which in the future could be used in conjunction with organic semiconductors.

Results of PRISMA/FFIORD extended mission and applicability to future formation flying and active debris removal missions

NASA Astrophysics Data System (ADS)

Delpech, Michel; Berges, Jean-Claude; Karlsson, Thomas; Malbet, Fabien

2013-07-01

CNES performed several experiments during the extended PRISMA mission which started in August 2011. A first session in October 2011 addressed two objectives: 1) demonstrate angles-only navigation to rendezvous with a non-cooperative object; 2) exercise transitions between RF-based and vision-based control during final formation acquisition. A complementary experiment in September 2012 mimicked some future astrometry mission and implemented the manoeuvres required to point the two satellite axis to a celestial target and maintain it fixed during some observation period. In the first sections, the paper presents the experiment motivations, describes its main design features including the guidance and control algorithms evolutions and provides a synthesis of the most significant results along with a discussion of the lessons learned. In the last part, the paper evokes the applicability of these experiment results to some active debris removal mission concept that is currently being studied.

[Basic questionnaire and methodological criteria for Surveys on Working Conditions, Employment, and Health in Latin America and the Caribbean].

PubMed

Benavides, Fernando G; Merino-Salazar, Pamela; Cornelio, Cecilia; Assunção, Ada Avila; Agudelo-Suárez, Andrés A; Amable, Marcelo; Artazcoz, Lucía; Astete, Jonh; Barraza, Douglas; Berhó, Fabián; Milián, Lino Carmenate; Delclòs, George; Funcasta, Lorena; Gerke, Johanna; Gimeno, David; Itatí-Iñiguez, María José; Lima, Eduardo de Paula; Martínez-Iñigo, David; Medeiros, Adriane Mesquita de; Orta, Lida; Pinilla, Javier; Rodrigo, Fernando; Rojas, Marianela; Sabastizagal, Iselle; Vallebuona, Clelia; Vermeylen, Greet; Villalobos, Gloria H; Vives, Alejandra

2016-10-10

This article aimed to present a basic questionnaire and minimum methodological criteria for consideration in future Surveys on Working Conditions, Employment, and Health in Latin America and the Caribbean. A virtual and face-to-face consensus process was conducted with participation by a group of international experts who used the surveys available up until 2013 as the point of departure for defining the proposal. The final questionnaire included 77 questions grouped in six dimensions: socio-demographic characteristics of workers and companies; employment conditions; working conditions; health status; resources and preventive activities; and family characteristics. The minimum methodological criteria feature the interviewee's home as the place for the interview and aspects related to the quality of the fieldwork. These results can help improve the comparability of future surveys in Latin America and the Caribbean, which would in turn help improve information on workers' heath in the region.

Aeroelasticity at the NASA Langley Research Center Recent progress, new challenges

NASA Technical Reports Server (NTRS)

Hanson, P. W.

1985-01-01

Recent progress in aeroelasticity, particularly at the NASA Langley Research Center is reviewed to look at the questions answered and questions raised, and to attempt to define appropriate research emphasis needed in the near future and beyond. The paper is focused primarily on the NASA Langley Research Center (LaRC) Program because Langley is the lead NASA center for aerospace structures research, and essentially is the only one working in depth in the area of aeroelasticity. Historical trends in aeroelasticity are reviewed broadly in terms of technology and staffing particularly at the LaRC. Then, selected studies of the Loads and Aeroelasticity Division at LaRC and others over the past three years are presented with attention paid to unresolved questions. Finally, based on the results of these studies and on perceptions of design trends and aircraft operational requirements, future research needs in aeroelasticity are discussed.

"Letting myself go forward past wrongs": How regulatory modes affect self-forgiveness.

PubMed

Pierro, Antonio; Pica, Gennaro; Giannini, Anna Maria; Higgins, E Tory; Kruglanski, Arie W

2018-01-01

The present research addresses the question of whether regulatory-mode orientations affect self-forgiveness. We expected that people with a strong locomotion orientation would be more inclined to self-forgiveness because of their tendencies toward movement and change, which focus them on the future, whereas people with a strong assessment orientation would refrain from self-forgiveness due to their evaluative tendencies which focus them on the past. These hypotheses were supported by the results in four studies that tested the relation between regulatory modes and self-forgiveness by measuring (Studies 1, 3 and 4) and manipulating (Study 2) regulatory-mode-orientations. Finally, in Study 4 we examined more closely our hypothesis that the relation between self-forgiveness and regulatory modes is mediated by past and future temporal foci. The implications of the results for regulatory mode theory are also discussed.

Nuclear analytical techniques in medicine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cesareo, R.

1988-01-01

This book acquaints one with the fundamental principles and the instrumentation relevant to analytical technique based on atomic and nuclear physics, as well as present and future biomedical applications. Besides providing a theoretical description of the physical phenomena, a large part of the book is devoted to applications in the medical and biological field, particularly in hematology, forensic medicine and environmental science. This volume reviews methods such as the possibility of carrying out rapid multi-element analysis of trace elements on biomedical samples, in vitro and in vivo, by XRF-analysis; the ability of the PIXE-microprobe to analyze in detail and tomore » map trace elements in fragments of biomedical samples or inside the cells; the potentiality of in vivo nuclear activation analysis for diagnostic purposes. Finally, techniques are described such as radiation scattering (elastic and inelastic scattering) and attenuation measurements which will undoubtedly see great development in the immediate future.« less

Chemical reacting flows

NASA Technical Reports Server (NTRS)

Mularz, Edward J.; Sockol, Peter M.

1987-01-01

Future aerospace propulsion concepts involve the combination of liquid or gaseous fuels in a highly turbulent internal air stream. Accurate predictive computer codes which can simulate the fluid mechanics, chemistry, and turbulence combustion interaction of these chemical reacting flows will be a new tool that is needed in the design of these future propulsion concepts. Experimental and code development research is being performed at Lewis to better understand chemical reacting flows with the long term goal of establishing these reliable computer codes. The approach to understanding chemical reacting flows is to look at separate simple parts of this complex phenomena as well as to study the full turbulent reacting flow process. As a result research on the fluid mechanics associated with chemical reacting flows was initiated. The chemistry of fuel-air combustion is also being studied. Finally, the phenomena of turbulence-combustion interaction is being investigated. This presentation will highlight research, both experimental and analytical, in each of these three major areas.

Understanding the ecology of child maltreatment: a review of the literature and directions for future research.

PubMed

Freisthler, Bridget; Merritt, Darcey H; LaScala, Elizabeth A

2006-08-01

Studies examining neighborhood characteristics in relation to social problems, including child maltreatment, have proliferated in the past 25 years. This article reviews the current state of knowledge of ecological studies of child maltreatment. Taken as a whole, these 18 studies document a stable ecological relationship among neighborhood impoverishment, housing stress, and rates of child maltreatment, as well as some evidence that unemployment, child care burden, and alcohol availability may contribute to child abuse and neglect. The authors include a discussion of methodological difficulties in conducting research at the neighborhood level and present a set of recommendations for future research that emphasizes movement from a simple examination of neighborhood-level characteristics toward a theoretically driven explication of processes and mechanisms supported by appropriate multilevel modeling techniques. The final goal of such efforts would be to enable practitioners to develop evidence-based neighborhood interventions that would prevent and reduce child abuse and neglect.

Redox cofactor engineering in industrial microorganisms: strategies, recent applications and future directions.

PubMed

Liu, Jiaheng; Li, Huiling; Zhao, Guangrong; Caiyin, Qinggele; Qiao, Jianjun

2018-05-01

NAD and NADP, a pivotal class of cofactors, which function as essential electron donors or acceptors in all biological organisms, drive considerable catabolic and anabolic reactions. Furthermore, they play critical roles in maintaining intracellular redox homeostasis. However, many metabolic engineering efforts in industrial microorganisms towards modification or introduction of metabolic pathways, especially those involving consumption, generation or transformation of NAD/NADP, often induce fluctuations in redox state, which dramatically impede cellular metabolism, resulting in decreased growth performance and biosynthetic capacity. Here, we comprehensively review the cofactor engineering strategies for solving the problematic redox imbalance in metabolism modification, as well as their features, suitabilities and recent applications. Some representative examples of in vitro biocatalysis are also described. In addition, we briefly discuss how tools and methods from the field of synthetic biology can be applied for cofactor engineering. Finally, future directions and challenges for development of cofactor redox engineering are presented.

Motion planning: A journey of robots, molecules, digital actors, and other artifacts

DOE Office of Scientific and Technical Information (OSTI.GOV)

Latombe, J.C.

1999-11-01

During the past three decades, motion planning has emerged as a crucial and productive research area in robotics. In the mid-1980s, the most advanced planners were barely able to compute collision-free paths for objects crawling in planar workspaces. Today, planners efficiently deal with robots with many degrees of freedom in complex environments. Techniques also exist to generate quasi-optimal trajectories, coordinate multiple robots, deal with dynamic and kinematic constraints, and handle dynamic environments. This paper describes some of these achievements, presents new problems that have recently emerged, discusses applications likely to motivate future research, and finally gives expectations for the comingmore » years. It stresses the fact that nonrobotics applications (e.g., graphic animation, surgical planning, computational biology) are growing in importance and are likely to shape future motion-planning research more than robotics itself.« less

Design, clinical translation and immunological response of biomaterials in regenerative medicine

NASA Astrophysics Data System (ADS)

Sadtler, Kaitlyn; Singh, Anirudha; Wolf, Matthew T.; Wang, Xiaokun; Pardoll, Drew M.; Elisseeff, Jennifer H.

2016-07-01

The field of regenerative medicine aims to replace tissues lost as a consequence of disease, trauma or congenital abnormalities. Biomaterials serve as scaffolds for regenerative medicine to deliver cells, provide biological signals and physical support, and mobilize endogenous cells to repair tissues. Sophisticated chemistries are used to synthesize materials that mimic and modulate native tissue microenvironments, to replace form and to elucidate structure-function relationships of cell-material interactions. The therapeutic relevance of these biomaterial properties can only be studied after clinical translation, whereby key parameters for efficacy can be defined and then used for future design. In this Review, we present the development and translation of biomaterials for two tissue engineering targets, cartilage and cornea, both of which lack the ability to self-repair. Finally, looking to the future, we discuss the role of the immune system in regeneration and the potential for biomaterial scaffolds to modulate immune signalling to create a pro-regenerative environment.

Childhood obesity-related endothelial dysfunction: an update on pathophysiological mechanisms and diagnostic advancements.

PubMed

Bruyndonckx, Luc; Hoymans, Vicky Y; Lemmens, Katrien; Ramet, José; Vrints, Christiaan J

2016-06-01

Childhood obesity jeopardizes a healthy future for our society's children as it is associated with increased cardiovascular morbidity and mortality later on in life. Endothelial dysfunction, the first step in the development of atherosclerosis, is already present in obese children and may well represent a targetable risk factor. Technological advancements in recent years have facilitated noninvasive measurements of endothelial homeostasis in children. Thereby this topic ultimately starts to get the attention it deserves. In this paper, we aim to summarize the latest insights on endothelial dysfunction in childhood obesity. We discuss methodological advancements in peripheral endothelial function measurement and newly identified diagnostic markers of vascular homeostasis. Finally, future challenges and perspectives are set forth on how to efficiently tackle the catastrophic rise in cardiovascular morbidity and mortality that will be inflicted on obese children if they are not treated optimally.

Discrimination, Subjective Wellbeing, and the Role of Gender: A Mediation Model of LGB Minority Stress.

PubMed

Conlin, Sarah E; Douglass, Richard P; Ouch, Staci

2017-10-26

The present study examined the link between discrimination and the three components of subjective wellbeing (positive and negative affect and life satisfaction) among a cisgender sample of lesbian, gay, and bisexual (LGB) adults. Specifically, we investigated internalized homonegativity and expectations of rejection as potential mediators of the links between discrimination and subjective wellbeing among a sample of 215 participants. Results from our structural equation model demonstrated a strong, positive direct link between discrimination and negative affect. Discrimination also had small, negative indirect effects on life satisfaction through our two mediators. Interestingly, neither discrimination nor our two mediators were related with positive affect, demonstrating the need for future research to uncover potential buffers of this link. Finally, our model evidenced configural, metric, and scalar invariance, suggesting that our model applies well for both women and men. Practical implications and future directions for research are discussed.

Geothermal Water Use: Life Cycle Water Consumption, Water Resource Assessment, and Water Policy Framework

DOE Data Explorer

Schroeder, Jenna N.

2014-06-10

This report examines life cycle water consumption for various geothermal technologies to better understand factors that affect water consumption across the life cycle (e.g., power plant cooling, belowground fluid losses) and to assess the potential water challenges that future geothermal power generation projects may face. Previous reports in this series quantified the life cycle freshwater requirements of geothermal power-generating systems, explored operational and environmental concerns related to the geochemical composition of geothermal fluids, and assessed future water demand by geothermal power plants according to growth projections for the industry. This report seeks to extend those analyses by including EGS flash, both as part of the life cycle analysis and water resource assessment. A regional water resource assessment based upon the life cycle results is also presented. Finally, the legal framework of water with respect to geothermal resources in the states with active geothermal development is also analyzed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hoette, Trisha Marie

Throughout history, as new chemical threats arose, strategies for the defense against chemical attacks have also evolved. As a part of an Early Career Laboratory Directed Research and Development project, a systems analysis of past, present, and future chemical terrorism scenarios was performed to understand how the chemical threats and attack strategies change over time. For the analysis, the difficulty in executing chemical attack was evaluated within a framework of three major scenario elements. First, historical examples of chemical terrorism were examined to determine how the use of chemical threats, versus other weapons, contributed to the successful execution of themore » attack. Using the same framework, the future of chemical terrorism was assessed with respect to the impact of globalization and new technologies. Finally, the efficacy of the current defenses against contemporary chemical terrorism was considered briefly. The results of this analysis justify the need for continued diligence in chemical defense.« less

Identification and impact of discoverers in online social systems

NASA Astrophysics Data System (ADS)

Medo, Matúš; Mariani, Manuel S.; Zeng, An; Zhang, Yi-Cheng

2016-09-01

Understanding the behavior of users in online systems is of essential importance for sociology, system design, e-commerce, and beyond. Most existing models assume that individuals in diverse systems, ranging from social networks to e-commerce platforms, tend to what is already popular. We propose a statistical time-aware framework to identify the users who differ from the usual behavior by being repeatedly and persistently among the first to collect the items that later become hugely popular. Since these users effectively discover future hits, we refer them as discoverers. We use the proposed framework to demonstrate that discoverers are present in a wide range of real systems. Once identified, discoverers can be used to predict the future success of new items. We finally introduce a simple network model which reproduces the discovery patterns observed in the real data. Our results open the door to quantitative study of detailed temporal patterns in social systems.

Identification and impact of discoverers in online social systems.

PubMed

Medo, Matúš; Mariani, Manuel S; Zeng, An; Zhang, Yi-Cheng

2016-09-30

Understanding the behavior of users in online systems is of essential importance for sociology, system design, e-commerce, and beyond. Most existing models assume that individuals in diverse systems, ranging from social networks to e-commerce platforms, tend to what is already popular. We propose a statistical time-aware framework to identify the users who differ from the usual behavior by being repeatedly and persistently among the first to collect the items that later become hugely popular. Since these users effectively discover future hits, we refer them as discoverers. We use the proposed framework to demonstrate that discoverers are present in a wide range of real systems. Once identified, discoverers can be used to predict the future success of new items. We finally introduce a simple network model which reproduces the discovery patterns observed in the real data. Our results open the door to quantitative study of detailed temporal patterns in social systems.

Planck and the reionization of the universe

NASA Astrophysics Data System (ADS)

Crill, Brendan

2016-03-01

Planck is the third-generation satellite aimed at measuring the cosmic microwave background, a relic of the hot big bang. Planck's temperature and polarization maps of the millimeter-wave sky have constrained parameters of the standard lambda-CDM model of cosmology to incredible precision, and have provided constraints on inflation in the very early universe. Planck's all-sky survey of polarization in seven frequency bands can remove contamination from nearby Galactic emission and constrain the optical depth of the reionized Universe, giving insight into the properties of the earliest star formation. The final 2016 data release from Planck will include a refined optical depth measurement using the full sensitivity of both the High Frequency and Low Frequency instruments. I present the status of the reionization measurement and discuss future prospects for further measurements of the early Universe with the CMB from Planck and future space and suborbital platforms.

MPI Runtime Error Detection with MUST: Advances in Deadlock Detection

DOE PAGES

Hilbrich, Tobias; Protze, Joachim; Schulz, Martin; ...

2013-01-01

The widely used Message Passing Interface (MPI) is complex and rich. As a result, application developers require automated tools to avoid and to detect MPI programming errors. We present the Marmot Umpire Scalable Tool (MUST) that detects such errors with significantly increased scalability. We present improvements to our graph-based deadlock detection approach for MPI, which cover future MPI extensions. Our enhancements also check complex MPI constructs that no previous graph-based detection approach handled correctly. Finally, we present optimizations for the processing of MPI operations that reduce runtime deadlock detection overheads. Existing approaches often require ( p ) analysis time permore » MPI operation, for p processes. We empirically observe that our improvements lead to sub-linear or better analysis time per operation for a wide range of real world applications.« less

Multimodal corridor and capacity analysis manual. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1998-12-31

This report presents the results of research carried out under NCHRP Project 8-31, Long-Term Availability of Multimodal Corridor Capacity. The report is presented as a manual on multimodal corridor and capacity analysis. Because transportation-system and corridor capacity for freight and passengers is critical for meeting current and future transportation demand, this manual will provide much needed assistance to a wide range of practitioners, particularly those engaged in performance analysis, capacity management, needs studies, systems planning, and corridor development planning--including major investment studies. It provides information regarding capacity analysis approaches for highways, rail, pipelines, and waterways and presents available options formore » enhancing corridor capacity and performance through various strategies such as new capacity development, freeing up unused capacity, or control of travel demand. Evaluation methods for these options are included.« less

Defining Priorities for Future Research: Results of the UK Kidney Transplant Priority Setting Partnership

PubMed Central

Metcalfe, Leanne; O’Donoghue, Katriona; Ball, Simon T.; Beale, Angela; Beale, William; Hilton, Rachel; Hodkinson, Keith; Lipkin, Graham W.; Loud, Fiona; Marson, Lorna P.; Morris, Peter J.

2016-01-01

Background It has been suggested that the research priorities of those funding and performing research in transplantation may differ from those of end service users such as patients, carers and healthcare professionals involved in day-to-day care. The Kidney Transplant Priority Setting Partnership (PSP) was established with the aim of involving all stakeholders in prioritising future research in the field. Methods The PSP methodology is as outlined by the James Lind Alliance. An initial survey collected unanswered research questions from patients, carers and clinicians. Duplicate and out-of-scope topics were excluded and the existing literature searched to identify topics answered by current evidence. An interim prioritisation survey asked patients and professionals to score the importance of the remaining questions to create a ranked long-list. These were considered at a final consensus workshop using a modified nominal group technique to agree a final top ten. Results The initial survey identified 497 questions from 183 respondents, covering all aspects of transplantation from assessment through to long-term follow-up. These were grouped into 90 unanswered “indicative” questions. The interim prioritisation survey received 256 responses (34.8% patients/carers, 10.9% donors and 54.3% professionals), resulting in a ranked list of 25 questions that were considered during the final workshop. Participants agreed a top ten priorities for future research that included optimisation of immunosuppression (improved monitoring, choice of regimen, personalisation), prevention of sensitisation and transplanting the sensitised patient, management of antibody-mediated rejection, long-term risks to live donors, methods of organ preservation, induction of tolerance and bioengineering of organs. There was evidence that patient and carer involvement had a significant impact on shaping the final priorities. Conclusions The final list of priorities relates to all stages of the transplant process, including access to transplantation, living donation, organ preservation, post-transplant care and management of the failing transplant. This list of priorities will provide an invaluable resource for researchers and funders to direct future activity. PMID:27776143

Defining Priorities for Future Research: Results of the UK Kidney Transplant Priority Setting Partnership.

PubMed

Knight, Simon R; Metcalfe, Leanne; O'Donoghue, Katriona; Ball, Simon T; Beale, Angela; Beale, William; Hilton, Rachel; Hodkinson, Keith; Lipkin, Graham W; Loud, Fiona; Marson, Lorna P; Morris, Peter J

2016-01-01

It has been suggested that the research priorities of those funding and performing research in transplantation may differ from those of end service users such as patients, carers and healthcare professionals involved in day-to-day care. The Kidney Transplant Priority Setting Partnership (PSP) was established with the aim of involving all stakeholders in prioritising future research in the field. The PSP methodology is as outlined by the James Lind Alliance. An initial survey collected unanswered research questions from patients, carers and clinicians. Duplicate and out-of-scope topics were excluded and the existing literature searched to identify topics answered by current evidence. An interim prioritisation survey asked patients and professionals to score the importance of the remaining questions to create a ranked long-list. These were considered at a final consensus workshop using a modified nominal group technique to agree a final top ten. The initial survey identified 497 questions from 183 respondents, covering all aspects of transplantation from assessment through to long-term follow-up. These were grouped into 90 unanswered "indicative" questions. The interim prioritisation survey received 256 responses (34.8% patients/carers, 10.9% donors and 54.3% professionals), resulting in a ranked list of 25 questions that were considered during the final workshop. Participants agreed a top ten priorities for future research that included optimisation of immunosuppression (improved monitoring, choice of regimen, personalisation), prevention of sensitisation and transplanting the sensitised patient, management of antibody-mediated rejection, long-term risks to live donors, methods of organ preservation, induction of tolerance and bioengineering of organs. There was evidence that patient and carer involvement had a significant impact on shaping the final priorities. The final list of priorities relates to all stages of the transplant process, including access to transplantation, living donation, organ preservation, post-transplant care and management of the failing transplant. This list of priorities will provide an invaluable resource for researchers and funders to direct future activity.

Dynamical Stochastic Processes of Returns in Financial Markets

NASA Astrophysics Data System (ADS)

Kim, Kyungsik; Kim, Soo Yong; Lim, Gyuchang; Zhou, Junyuan; Yoon, Seung-Min

2006-03-01

We show how the evolution of probability distribution functions of the returns from the tick data of the Korean treasury bond futures (KTB) and the S&P 500 stock index can be described by means of the Fokker-Planck equation. We derive the Fokker- Planck equation from the estimated Kramers-Moyal coefficients estimated directly from the empirical data. By analyzing the statistics of the returns, we present the quantitative deterministic and random influences on both financial time series, for which we can give a simple physical interpretation. Finally, we remark that the diffusion coefficient should be significantly considered to make a portfolio.

NeuroMind: Past, present, and future.

PubMed

Kubben, Pieter L

2017-01-01

This narrative report describes the underlying rationale and technical developments of NeuroMind, a mobile clinical decision support system for neurosurgery. From the perspective of a neurosurgeon - (app) developer it explains how technical progress has shaped the world's "most rated and highest rated" neurosurgical mobile application, with particular attention for operating system diversity on mobile hardware, cookbook medicine, regulatory affairs (in particular regarding software as a medical device), and new developments in the field of clinical data science, machine learning, and predictive analytics. Finally, the concept of "computational neurosurgery" is introduced as a vehicle to reach new horizons in neurosurgery.

Brain Imaging, Forward Inference, and Theories of Reasoning

PubMed Central

Heit, Evan

2015-01-01

This review focuses on the issue of how neuroimaging studies address theoretical accounts of reasoning, through the lens of the method of forward inference (Henson, 2005, 2006). After theories of deductive and inductive reasoning are briefly presented, the method of forward inference for distinguishing between psychological theories based on brain imaging evidence is critically reviewed. Brain imaging studies of reasoning, comparing deductive and inductive arguments, comparing meaningful versus non-meaningful material, investigating hemispheric localization, and comparing conditional and relational arguments, are assessed in light of the method of forward inference. Finally, conclusions are drawn with regard to future research opportunities. PMID:25620926

Brettanomyces bruxellensis yeasts: impact on wine and winemaking.

PubMed

Agnolucci, Monica; Tirelli, Antonio; Cocolin, Luca; Toffanin, Annita

2017-09-21

Yeasts belonging to the Brettanomyces/Dekkera genus are non-conventional yeasts, which affect winemaking by causing wine spoilage all over the world. This mini-review focuses on recent results concerning the presence of Brettanomyces bruxellensis throughout the wine processing chain. Here, culture-dependent and independent methods to detect this yeast on grapes and at the very early stage of wine production are encompassed. Chemical, physical and biological tools, devised for the prevention and control of such a detrimental species during winemaking are also presented. Finally, the mini-review identifies future research areas relevant to the improvement of wine safety and sensory profiles.

Proceedings of the drug testing laboratory managers symposium, 28 January--1 February 1974. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Noe, E.R.; Romanchick, W.A.; Ainsworth, C.A. III

1975-06-01

This report deals with broad concepts of managing mass screening programs for drugs of abuse; e.g., morphine, barbiturate, amphetamine, cocaine, and methaqualone. The interactions of the screening process and of the rehabilitation program were covered. Psychotherapy and group therapy are both utilized in rehabilitation programs. The semiautomated radioimmunoassay (RIA) screening procedures are both sensitive and specific at nanogram quantities. Future evaluations of a wafer disk transferral system and of a latex test for morphine are presented. The unique quality control system employed by military drug abuse testing laboratories is discussed. (Author) (GRA)

An experimental investigation of ejector performance based upon different refrigerants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, S.L.; Yen, J.Y.; Huang, M.C.

1998-12-31

This article experimentally compares the characteristics of different refrigerants as the working fluid in an ejector cooling system. The study covers common refrigerants including R-113, R-114, R-142b, and R-718. The critical choking conditions against the variation of condenser back pressure, the evaporator pressure, and the generator pressure are determined for each refrigerant. The results are compiled into a convenient performance curve and COP chart. These results can serve as an important reference for future design of ejector cooling systems. Finally, this paper presents a comparison of the performances of different refrigerants in an ejector cooling system.

Motivation: What have we learned and what is still missing?

PubMed

Studer, B; Knecht, S

2016-01-01

This final chapter deliberates three overarching topics and conclusions of the research presented in this volume: the endurance of the concept of extrinsic vs intrinsic motivation, the importance of considering subjective costs of activities when aiming to understand and enhance motivation, and current knowledge of the neurobiological underpinnings of motivation. Furthermore, three topics for future motivation research are outlined, namely the assessment and determinants of intrinsic benefits, the reconciliation of activity-specific motivation models with generalized motivation impairments in clinical populations, and the motivational dynamics of groups. © 2016 Elsevier B.V. All rights reserved.

Ejected particle size measurement using Mie scattering in high explosive driven shockwave experiments

DOE PAGES

Monfared, Shabnam Khalighi; Buttler, William Tillman; Frayer, Daniel K.; ...

2015-06-11

In this paper, we report on the development of a diagnostic to provide constraints on the size of particles ejected from shocked metallic surfaces. The diagnostic is based on measurements of the intensity of laser light transmitted through a cloud of ejected particles as well as the angular distribution of scattered light, and the analysis of the resulting data is done using the Mie solution. Finally, we describe static experiments to test our experimental apparatus and present initial results of dynamic experiments on Sn targets. Improvements for future experiments are briefly discussed.

Research Update: The materials genome initiative: Data sharing and the impact of collaborative ab initio databases

DOE PAGES

Jain, Anubhav; Persson, Kristin A.; Ceder, Gerbrand

2016-03-24

Materials innovations enable new technological capabilities and drive major societal advancements but have historically required long and costly development cycles. The Materials Genome Initiative (MGI) aims to greatly reduce this time and cost. Here, we focus on data reuse in the MGI and, in particular, discuss the impact of three different computational databases based on density functional theory methods to the research community. Finally, we discuss and provide recommendations on technical aspects of data reuse, outline remaining fundamental challenges, and present an outlook on the future of MGI's vision of data sharing.

TVA's photovoltaic activities

NASA Astrophysics Data System (ADS)

Chinery, G. T.; Wood, J. M.

1985-08-01

This paper describes the Tennessee Valley Authority's (TVA) current photovoltaic (PV) activities. These include four roof-mounted 4 kWp residential arrays (which are also Southeast Residential Station field sites) and two 5-6 kWp commercial sites, all grid connected with no battery storage. Also included are approximately 30 kWp of non-grid-connected remote sites with storage (remote lighting, weather stations, etc.). Monitoring results from the two 'online' residential systems are presented. Finally, TVA's future PV plans are discussed, both with respect to interfacing with a multitude of residential and commercial cogenerators and with regard to possible TVA PV central station plans.

A Study of Future Communications Concepts and Technologies for the National Airspace System - Part IV

NASA Technical Reports Server (NTRS)

Ponchak, Denise S.; Apaza, Rafael D.; Wichgers, Joel M.; Haynes, Brian; Roy, Aloke

2015-01-01

The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) is investigating current and anticipated wireless communications concepts and technologies that the National Airspace System (NAS) may need in the next 50 years. NASA has awarded three NASA Research Announcements (NAR) studies with the objective to determine the most promising candidate technologies for air-to-air and air-to-ground data exchange and analyze their suitability in a post-NextGen NAS environment. This paper will present the final results describing the communications challenges and opportunities that have been identified as part of the study.

Alternative aircraft fuels

NASA Technical Reports Server (NTRS)

Longwell, J. P.; Grobman, J. S.

1977-01-01

The efficient utilization of fossil fuels by future jet aircraft may necessitate the broadening of current aviation turbine fuel specifications. The most significant changes in specifications would be an increased aromatics content and a higher final boiling point in order to minimize refinery energy consumption and costs. These changes would increase the freezing point and might lower the thermal stability of the fuel, and could cause increased pollutant emissions, increased combustor liner temperatures, and poorer ignition characteristics. The effects that broadened specification fuels may have on present-day jet aircraft and engine components and the technology required to use fuels with broadened specifications are discussed.

Social network supported process recommender system.

PubMed

Ye, Yanming; Yin, Jianwei; Xu, Yueshen

2014-01-01

Process recommendation technologies have gained more and more attention in the field of intelligent business process modeling to assist the process modeling. However, most of the existing technologies only use the process structure analysis and do not take the social features of processes into account, while the process modeling is complex and comprehensive in most situations. This paper studies the feasibility of social network research technologies on process recommendation and builds a social network system of processes based on the features similarities. Then, three process matching degree measurements are presented and the system implementation is discussed subsequently. Finally, experimental evaluations and future works are introduced.

NAS: The first year

NASA Technical Reports Server (NTRS)

Bailey, F. R.; Kutler, Paul

1988-01-01

Discussed are the capabilities of NASA's Numerical Aerodynamic Simulation (NAS) Program and its application as an advanced supercomputing system for computational fluid dynamics (CFD) research. First, the paper describes the NAS computational system, called the NAS Processing System Network, and the advanced computational capabilities it offers as a consequence of carrying out the NAS pathfinder objective. Second, it presents examples of pioneering CFD research accomplished during NAS's first operational year. Examples are included which illustrate CFD applications for predicting fluid phenomena, complementing and supplementing experimentation, and aiding in design. Finally, pacing elements and future directions for CFD and NAS are discussed.

Modelling Groundwater Depletion at Regional and Global Scales: Present State and Future Prospects.

NASA Technical Reports Server (NTRS)

Wada, Yoshihide

2015-01-01

Except for frozen water in ice and glaciers, groundwater is the world's largest distributed store of freshwater and has strategic importance to global food and water security. In this paper, the most recent advances quantifying groundwater depletion (GWD) are comprehensively reviewed. This paper critically evaluates the recently advanced modeling approaches estimating GWD at regional and global scales, and the evidence of feedbacks to the Earth system including sea-level rise associated with GWD. Finally, critical challenges and opportunities in the use of groundwater are identified for the adaption to growing food demand and uncertain climate.

Future capabilities for the Deep Space Network

NASA Technical Reports Server (NTRS)

Berner, J. B.; Bryant, S. H.; Andrews, K. S.

2004-01-01

This paper will look at three new capabilities that are in different stages of development. First, turbo decoding, which provides improved telemetry performance for data rates up to about 1 Mbps, will be discussed. Next, pseudo-noise ranging will be presented. Pseudo-noise ranging has several advantages over the current sequential ranging, anmely easier operations, improved performance, and the capability to be used in a regenerative implementation on a spacecraft. Finally, Low Density Parity Check decoding will be discussed. LDPC codes can provide performance that matches or slightly exceed turbo codes, but are designed for use in the 10 Mbps range.