Emotional discussions reduce memory recall.

PubMed

Soleti, Emanuela; Wright, Daniel B; Curci, Antonietta

2017-05-01

People often discuss events they have seen and these discussions can influence later recollections. We investigated the effects of factual, emotional, and free retelling discussion on memory recollections of individuals who have witnessed an event. Participants were shown a video, made an initial individual recall, participated in one of the three retelling conditions (emotional versus factual versus free) or a control condition, and then recalled the event individually again. Participants in the factual and free retelling conditions reported more items not previously recalled than participants in the control condition did, while the emotional condition did not show the same advantage. Participants in all three retelling conditions failed to report more previously recalled items as compared with the control condition. Finally, a memory conformity effect was observed for all three retelling conditions. These findings suggest that eyewitnesses' discussions may influence the accuracy of subsequent memory reports, especially when these discussions are focused on emotional details and thoughts.

Contributions of episodic retrieval and mentalizing to autobiographical thought: evidence from functional neuroimaging, resting-state connectivity, and fMRI meta-analyses

PubMed Central

Andrews-Hanna, Jessica R.; Saxe, Rebecca; Yarkoni, Tal

2014-01-01

A growing number of studies suggest the brain’s “default network” becomes engaged when individuals recall their personal past or simulate their future. Recent reports of heterogeneity within the network raises the possibility that these autobiographical processes are comprised of multiple component processes, each supported by distinct functional-anatomic subsystems. We previously hypothesized that a medial temporal subsystem contributes to autobiographical memory and future thought by enabling individuals to retrieve prior information and bind this information into a mental scene. Conversely, a dorsal medial subsystem was proposed to support social-reflective aspects of autobiographical thought, allowing individuals to reflect on the mental states of one’s self and others (i.e. “mentalizing”). To test these hypotheses, we first examined activity in the default network subsystems as participants performed two commonly employed tasks of episodic retrieval and mentalizing. In a subset of participants, relationships among task-evoked regions were examined at rest, in the absence of an overt task. Finally, large-scale fMRI meta-analyses were conducted to identify brain regions that most strongly predicted the presence of episodic retrieval and mentalizing, and these results were compared to meta-analyses of autobiographical tasks. Across studies, laboratory-based episodic retrieval tasks were preferentially linked to the medial temporal subsystem, while mentalizing tasks were preferentially linked to the dorsal medial subsystem. In turn, autobiographical tasks engaged aspects of both subsystems. These results suggest the default network is a heterogeneous brain system whose subsystems support distinct component processes of autobiographical thought. PMID:24486981

Contributions of episodic retrieval and mentalizing to autobiographical thought: evidence from functional neuroimaging, resting-state connectivity, and fMRI meta-analyses.

PubMed

Andrews-Hanna, Jessica R; Saxe, Rebecca; Yarkoni, Tal

2014-05-01

A growing number of studies suggest the brain's "default network" becomes engaged when individuals recall their personal past or simulate their future. Recent reports of heterogeneity within the network raise the possibility that these autobiographical processes comprised of multiple component processes, each supported by distinct functional-anatomic subsystems. We previously hypothesized that a medial temporal subsystem contributes to autobiographical memory and future thought by enabling individuals to retrieve prior information and bind this information into a mental scene. Conversely, a dorsal medial subsystem was proposed to support social-reflective aspects of autobiographical thought, allowing individuals to reflect on the mental states of one's self and others (i.e. "mentalizing"). To test these hypotheses, we first examined activity in the default network subsystems as participants performed two commonly employed tasks of episodic retrieval and mentalizing. In a subset of participants, relationships among task-evoked regions were examined at rest, in the absence of an overt task. Finally, large-scale fMRI meta-analyses were conducted to identify brain regions that most strongly predicted the presence of episodic retrieval and mentalizing, and these results were compared to meta-analyses of autobiographical tasks. Across studies, laboratory-based episodic retrieval tasks were preferentially linked to the medial temporal subsystem, while mentalizing tasks were preferentially linked to the dorsal medial subsystem. In turn, autobiographical tasks engaged aspects of both subsystems. These results suggest the default network is a heterogeneous brain system whose subsystems support distinct component processes of autobiographical thought. Copyright © 2014 Elsevier Inc. All rights reserved.

Sentence-position effects on children's perception and production of English third person singular -s.

PubMed

Sundara, Megha; Demuth, Katherine; Kuhl, Patricia K

2011-02-01

Two-year-olds produce third person singular -s more accurately on verbs in sentence-final position as compared with verbs in sentence-medial position. This study was designed to determine whether these sentence-position effects can be explained by perceptual factors. For this purpose, the authors compared 22- and 27-month-olds' perception and elicited production of third person singular -s in sentence-medial versus-final position. The authors assessed perception by measuring looking/listening times to a 1-screen display of a cartoon paired with a grammatical versus an ungrammatical sentence (e.g., She eats now vs. She eat now). Children at both ages demonstrated sensitivity to the presence/absence of this inflectional morpheme in sentence-final, but not sentence-medial, position. Children were also more accurate at producing third person singular -s sentence finally, and production accuracy was predicted by vocabulary measures as well as by performance on the perception task. These results indicate that children's more accurate production of third person singular -s in sentence-final position cannot be explained by articulatory factors alone but that perceptual factors play an important role in accounting for early patterns of production. The findings also indicate that perception and production of inflectional morphemes may be more closely related than previously thought.

Music and aggression: the impact of sexual-aggressive song lyrics on aggression-related thoughts, emotions, and behavior toward the same and the opposite sex.

PubMed

Fischer, Peter; Greitemeyer, Tobias

2006-09-01

Three studies examined the impact of sexual-aggressive song lyrics on aggressive thoughts, emotions, and behavior toward the same and the opposite sex. In Study 1, the authors directly manipulated whether male or female participants listened to misogynous or neutral song lyrics and measured actual aggressive behavior. Male participants who were exposed to misogynous song lyrics administered more hot chili sauce to a female than to a male confederate. Study 2 shed some light on the underlying psychological processes: Male participants who heard misogynous song lyrics recalled more negative attributes of women and reported more feelings of vengeance than when they heard neutral song lyrics. In addition, men-hating song lyrics had a similar effect on aggression-related responses of female participants toward men. Finally, Study 3 replicated the findings of the previous two studies with an alternative measure of aggressive behavior as well as a more subtle measure of aggressive cognitions. The results are discussed in the framework of the General Aggression Model.

Sri Lankan health care provision and medical education: a discussion

PubMed Central

Paskins, Z

2001-01-01

My elective was spent at a teaching hospital in Galle, in Sri Lanka. My time was spent shadowing final year students in the specialties of general medicine and paediatrics. This period provided me with much food for thought in comparing and contrasting the health service in Sri Lanka with that of the UK and also considering the differences in the style of medical education. In addition, during my stay, I was able to gain some appreciation of the political and organisational problems faced by a country in the midst of a civil war.
In this report, I have attempted to integrate an account of my observations with a discussion of the thoughts and emotions that I experienced while working in a developing country. Studying in Sri Lanka facilitated my appreciation of facets of British health care and medical education that I had not previously considered. However, fewer resources do not necessarily mean poorer patient care: could Britain have something to learn from the Sri Lankan Health Service?


Keywords: Sri Lanka; elective; medical education PMID:11161103

Creativity-the unconscious foundations of the incubation period.

PubMed

Ritter, Simone M; Dijksterhuis, Ap

2014-01-01

Creativity is one of the most important assets we have to navigate through the fast changing world of the 21st century. Anecdotal accounts of creative individuals suggest that oftentimes, creative discoveries result from a process whereby initial conscious thought is followed by a period during which one refrains from task-related conscious thought. For example, one may spend an embarrassing amount of time thinking about a problem when the solution suddenly pops into consciousness while taking a shower. Not only creative individuals but also traditional theories of creativity have put a lot of emphasis on this incubation stage in creative thinking. The aim of the present article is twofold. First, an overview of the domain of incubation and creativity is provided by reviewing and discussing studies on incubation, mind-wandering, and sleep. Second, the causes of incubation effects are discussed. Previously, little attention has been paid to the causes of incubation effects and most findings do not really speak to whether the effects should be explained by unconscious processes or merely by consequences of a period of distraction. In the latter case, there is no need to assume active unconscious processes. The findings discussed in the current article support the idea that it is not merely the absence of conscious thought that drives incubation effects, but that during an incubation period unconscious processes contribute to creative thinking. Finally, practical implications and directions for future research will be discussed.

Using natural archives to track sources and long-term trends of pollution: some final thoughts and suggestions for future directions

USGS Publications Warehouse

Blais, Jules M.; Rosen, Michael R.; Smol, John P.

2015-01-01

Newly produced, as well as some so-called legacy contaminants, continue to be released into the environment at an accelerated rate. Given the general lack of integrated, direct monitoring programs, the use of natural archival records of contaminants will almost certainly continue to increase. We conclude this volume with a short chapter highlighting some of our final thoughts, with a focus on a call to action to develop and apply methodologies to assess the fidelity of the archival record.

Occupational/Career Decision-Making Thought Processes of Adolescents of High Intellectual Ability

ERIC Educational Resources Information Center

Jung, Jae Yup

2017-01-01

Three competing models of the career decision-making thought processes of adolescents of high intellectual ability were tested in this study. Survey data were collected from 664 intellectually gifted Australian adolescents and analyzed using structural equation modeling procedures. The finally accepted, optimal model suggested that, regardless of…

Thought leadership: A new indicator for national and institutional comparison

DOE PAGES

Klavans, Richard; Boyack, Kevin W.

2008-03-08

This article introduces a new method for evaluating national publication activities. This new indicator, thought leadership, captures whether the nation is a thought leader (building on the more recently cited literature for that field) or follower (building on the older cited literature for that field). Publication data for 2003 are used to illustrate which nations tend to build on the more recent discoveries in chemistry and clinical medicine. Finally, implications for national and laboratory policy are discussed.

ScienceCast 77: Weird Planets

NASA Image and Video Library

2012-09-06

Once, astronomers thought planets couldn't form around binary stars. Now Kepler has found a whole system of planers orbiting a double star. This finding shows that planetary systems are weirder and more abundant than previously thought.

Food for thought: examining the relationship between food thought suppression and weight-related outcomes.

PubMed

Barnes, Rachel D; Tantleff-Dunn, Stacey

2010-08-01

The current study sought to extend previous eating behaviors and thought suppression literature by assessing the relationship between food thought suppression and weight-related outcomes. Three hundred and twelve overweight/obese community men and women completed self-report measures of thought suppression, weight history, and eating behaviors. Women were more likely than men to endorse food thought suppression, as were individuals who currently were dieting, when compared with those nondieters. Food thought suppression also predicted binge eating, food cravings, and other eating disordered symptoms. Results have implications for obesity and support further exploration of third wave interventions, such as Acceptance and Commitment Therapy and Mindfulness, in the treatment of obesity. 2010 Elsevier Ltd. All rights reserved.

Utilization and value of personal digital assistants on an epidemiology final examination.

PubMed

Lawler, Frank H; Cacy, Jim

2005-01-01

The utility of personal digital assistants (PDAs) in basic science medical education is uncertain. Student outcomes on an epidemiology course final examination for academic years 2003 and 2004 were examined. Students were given permission to use PDAs on the final examination, and self-selected whether these instruments were used. Performance on the examination based on use of a PDA and whether students thought it was useful for the examination was compared. A total of 389 students took the final examination, with an 88% response rate to the survey questions. No statistically significant differences were found on final examination scores. No trends toward significance were found on analyses of the total examination, specific topical domains, or on specific questions where a PDA might be expected to be especially useful. From this study, it can be concluded that use of PDAs and whether students thought they might be helpful had no measurable effect on performance on an epidemiology final examination. Further delineation of the possible use of PDAs in a basic science course and on the final examination is indicated.

Exaggerated, mispredicted, and misplaced: when "it's the thought that counts" in gift exchanges.

PubMed

Zhang, Yan; Epley, Nicholas

2012-11-01

Gift-giving involves both the objective value of a gift and the symbolic meaning of the exchange. The objective value is sometimes considered of secondary importance as when people claim, "It's the thought that counts." We evaluated when and how mental state inferences count in gift exchanges. Because considering another's thoughts requires motivation and deliberation, we predicted gift givers' thoughts would increase receivers' appreciation only when triggered to consider a giver's thoughts, such as when a friend gives a bad gift. Because gift givers do not experience this trigger, we expected they would mispredict when their thoughts count and when they do not. Three experiments support these predictions. A final experiment demonstrated that thoughts "count" for givers by increasing social connection to the receiver. These results suggest that mental state inferences are not automatic in social interactions and that inferences about how much thoughts count are systematically miscalibrated. (PsycINFO Database Record (c) 2012 APA, all rights reserved).

Spatially robust estimates of biological nitrogen (N) fixation imply substantial human alteration of the tropical N cycle

USGS Publications Warehouse

Sullivan, Benjamin W.; Smith, William K.; Townsend, Alan R.; Nasto, Megan K.; Reed, Sasha C.; Chazdon, Robin L.; Cleveland, Cory C.

2014-01-01

Biological nitrogen fixation (BNF) is the largest natural source of exogenous nitrogen (N) to unmanaged ecosystems and also the primary baseline against which anthropogenic changes to the N cycle are measured. Rates of BNF in tropical rainforest are thought to be among the highest on Earth, but they are notoriously difficult to quantify and are based on little empirical data. We adapted a sampling strategy from community ecology to generate spatial estimates of symbiotic and free-living BNF in secondary and primary forest sites that span a typical range of tropical forest legume abundance. Although total BNF was higher in secondary than primary forest, overall rates were roughly five times lower than previous estimates for the tropical forest biome. We found strong correlations between symbiotic BNF and legume abundance, but we also show that spatially free-living BNF often exceeds symbiotic inputs. Our results suggest that BNF in tropical forest has been overestimated, and our data are consistent with a recent top-down estimate of global BNF that implied but did not measure low tropical BNF rates. Finally, comparing tropical BNF within the historical area of tropical rainforest with current anthropogenic N inputs indicates that humans have already at least doubled reactive N inputs to the tropical forest biome, a far greater change than previously thought. Because N inputs are increasing faster in the tropics than anywhere on Earth, both the proportion and the effects of human N enrichment are likely to grow in the future.

Do patients have duties?

PubMed Central

Evans, H M

2007-01-01

The notion of patients' duties has received periodic scholarly attention but remains overwhelmed by attention to the duties of healthcare professionals. In a previous paper the author argued that patients in publicly funded healthcare systems have a duty to participate in clinical research, arising from their debt to previous patients. Here the author proposes a greatly extended range of patients' duties grounding their moral force distinctively in the interests of contemporary and future patients, since medical treatment offered to one patient is always liable to be an opportunity cost (however justifiable) in terms of medical treatment needed by other patients. This generates both negative and positive duties. Ten duties—enjoining obligations ranging from participation in healthcare schemes to promoting one's own earliest recovery from illness—are proposed. The characteristics of these duties, including their basis, moral force, extent and enforceability, are considered. They are tested against a range of objections—principled, societal, epistemological and practical—and found to survive. Finally, the paper suggests that these duties could be thought to reinforce a regrettably adversarial characteristic, shared with rights‐based approaches, and that a preferable alternative might be sought through the (here unexplored) notion of a “virtuous patient” contributing to a problem‐solving partnership with the clinician. However, in defining and giving content to that partnership, there is a clear role for most, if not all, of the proposed duties; their value thus extends beyond the adversarial context in which they might first be thought to arise. PMID:18055897

Towards a theory of intention: An application of quantum mechanics within psychotherapy

NASA Astrophysics Data System (ADS)

Van Wyck, Jennifer

This study incorporated grounded research methodology to analyze and code three fields of research: psychoneuroimmunology, psychokinesis, and guided imagery. The works of Tiller (2001, 2007) and Dyer (2004) were used as a validity check for the grounded theory results and provided further input into a final theory of intention. It was found that intention requires three elements to be most successful in producing targeted outcomes. These include consciousness, thought, and emotion. The emotional aspect of intention had previously been mentioned but never incorporated into earlier theories of intention and appears to be a new finding that has potentially strong implications. The paper concludes with a discussion of how the theory of intention can inform practice in the field of psychotherapy.

Thought Control Ability Is Different from Rumination in Explaining the Association between Neuroticism and Depression: A Three-Study Replication

PubMed Central

Lu, Feng-Ying; Yang, Wen-Jing; Zhang, Qing-Lin; Qiu, Jiang

2017-01-01

Neuroticism is the most common vulnerability factor of depression. However, the mechanism underlying this vulnerability is still unclear. Previous studies suggested that rumination intensifies the negative effect of neuroticism on depression. However, whether cognitive control could explain the association between neuroticism and depression remains unclear to date. Therefore, this study evaluated the indirect effects of rumination and thought control on the relationship between neuroticism and depression. Seven self-report measures were employed among healthy and main depression disorder (MDD) participants. Three studies were used to examine the hypotheses. Results of the three studies showed significant correlations among neuroticism, rumination, thought control, and depression. Rumination mediated the link between neuroticism and depression among healthy young adults, and this finding replicated previous studies. This study provided new evidence that thought control mediates the association between neuroticism and depression in both healthy and MDD populations. In conclusion, rumination increases neuroticism risk for depression, but high-level thought control decreases the effect of neuroticism on depression. This study may serve as a reference to develop effective and focused interventions for MDD patients. PMID:28620326

Functional dependence of neuroligin on a new non-PDZ intracellular domain

PubMed Central

Shipman, Seth L; Schnell, Eric; Hirai, Takaaki; Chen, Bo-Shiun; Roche, Katherine W; Nicoll, Roger A

2011-01-01

Neuroligins, a family of postsynaptic adhesion molecules, are important in synaptogenesis through a well-characterized trans-synaptic interaction with neurexin. In addition, neuroligins are thought to drive postsynaptic assembly through binding of their intracellular domain to PSD-95. However, there is little direct evidence to support the functional necessity of the neuroligin intracellular domain in postsynaptic development. We found that presence of endogenous neuroligin obscured the study of exogenous mutated neuroligin. We therefore used chained microRNAs in rat organotypic hippocampal slices to generate a reduced background of endogenous neuroligin. On this reduced background, we found that neuroligin function was critically dependent on the cytoplasmic tail. However, this function required neither the PDZ ligand nor any other previously described cytoplasmic binding domain, but rather required a previously unknown conserved region. Mutation of a single critical residue in this region inhibited neuroligin-mediated excitatory synaptic potentiation. Finally, we found a functional distinction between neuroligins 1 and 3. PMID:21532576

Mating in the Closest Living Relatives of Animals Is Induced by a Bacterial Chondroitinase.

PubMed

Woznica, Arielle; Gerdt, Joseph P; Hulett, Ryan E; Clardy, Jon; King, Nicole

2017-09-07

We serendipitously discovered that the marine bacterium Vibrio fischeri induces sexual reproduction in one of the closest living relatives of animals, the choanoflagellate Salpingoeca rosetta. Although bacteria influence everything from nutrition and metabolism to cell biology and development in eukaryotes, bacterial regulation of eukaryotic mating was unexpected. Here, we show that a single V. fischeri protein, the previously uncharacterized EroS, fully recapitulates the aphrodisiac-like activity of live V. fischeri. EroS is a chondroitin lyase; although its substrate, chondroitin sulfate, was previously thought to be an animal synapomorphy, we demonstrate that S. rosetta produces chondroitin sulfate and thus extend the ancestry of this important glycosaminoglycan to the premetazoan era. Finally, we show that V. fischeri, purified EroS, and other bacterial chondroitin lyases induce S. rosetta mating at environmentally relevant concentrations, suggesting that bacteria likely regulate choanoflagellate mating in nature. Copyright © 2017 Elsevier Inc. All rights reserved.

Identification of Eye-Specific Domains and Their Relation to Callosal Connections in Primary Visual Cortex of Long Evans Rats

PubMed Central

Laing, R.J.; Turecek, J.; Takahata, T.; Olavarria, J.F.

2015-01-01

Ocular dominance columns (ODCs) exist in many primates and carnivores, but it is believed that they do not exist in rodents. Using a combination of transneuronal tracing, in situ hybridization for Zif268 and electrophysiological recordings, we show that inputs from both eyes are largely segregated in the binocular region of V1 in Long Evans rats. We also show that, interposed between this binocular region and the lateral border of V1, there lies a strip of cortex that is strongly dominated by the contralateral eye. Finally, we show that callosal connections colocalize primarily with ipsilateral eye domains in the binocular region and with contralateral eye input in the lateral cortical strip, mirroring the relationship between patchy callosal connections and specific sets of ODCs described previously in the cat. Our results suggest that development of cortical modular architecture is more conserved among rodents, carnivores, and primates than previously thought. PMID:24969475

Creativity—the unconscious foundations of the incubation period

PubMed Central

Ritter, Simone M.; Dijksterhuis, Ap

2014-01-01

Creativity is one of the most important assets we have to navigate through the fast changing world of the 21st century. Anecdotal accounts of creative individuals suggest that oftentimes, creative discoveries result from a process whereby initial conscious thought is followed by a period during which one refrains from task-related conscious thought. For example, one may spend an embarrassing amount of time thinking about a problem when the solution suddenly pops into consciousness while taking a shower. Not only creative individuals but also traditional theories of creativity have put a lot of emphasis on this incubation stage in creative thinking. The aim of the present article is twofold. First, an overview of the domain of incubation and creativity is provided by reviewing and discussing studies on incubation, mind-wandering, and sleep. Second, the causes of incubation effects are discussed. Previously, little attention has been paid to the causes of incubation effects and most findings do not really speak to whether the effects should be explained by unconscious processes or merely by consequences of a period of distraction. In the latter case, there is no need to assume active unconscious processes. The findings discussed in the current article support the idea that it is not merely the absence of conscious thought that drives incubation effects, but that during an incubation period unconscious processes contribute to creative thinking. Finally, practical implications and directions for future research will be discussed. PMID:24782742

Confident failures: Lapses of working memory reveal a metacognitive blind spot.

PubMed

Adam, Kirsten C S; Vogel, Edward K

2017-07-01

Working memory performance fluctuates dramatically from trial to trial. On many trials, performance is no better than chance. Here, we assessed participants' awareness of working memory failures. We used a whole-report visual working memory task to quantify both trial-by-trial performance and trial-by-trial subjective ratings of inattention to the task. In Experiment 1 (N = 41), participants were probed for task-unrelated thoughts immediately following 20% of trials. In Experiment 2 (N = 30), participants gave a rating of their attentional state following 25% of trials. Finally, in Experiments 3a (N = 44) and 3b (N = 34), participants reported confidence of every response using a simple mouse-click judgment. Attention-state ratings and off-task thoughts predicted the number of items correctly identified on each trial, replicating previous findings that subjective measures of attention state predict working memory performance. However, participants correctly identified failures on only around 28% of failure trials. Across experiments, participants' metacognitive judgments reliably predicted variation in working memory performance but consistently and severely underestimated the extent of failures. Further, individual differences in metacognitive accuracy correlated with overall working memory performance, suggesting that metacognitive monitoring may be key to working memory success.

Prevalence and determinants of direct and generative modes of production of episodic future thoughts in the word cueing paradigm.

PubMed

Jeunehomme, Olivier; D'Argembeau, Arnaud

2016-01-01

Recent research suggests that episodic future thoughts can be formed through the same dual mechanisms, direct and generative, as autobiographical memories. However, the prevalence and determinants of the direct production of future event representations remain unclear. Here, we addressed this issue by collecting self-reports of production modes, response times (RTs), and verbal protocols for the production past and future events in the word cueing paradigm. Across three experiments, we found that both past and future events were frequently reported to come directly to mind in response to the cue, and RTs confirmed that events were produced faster for direct than for generative responses. When looking at the determinants of direct responses, we found that most past and future events that were directly produced had already been thought of on a previous occasion, and the frequency of previous thoughts predicted the occurrence of direct access. The direct production of autobiographical thoughts was also more frequent for past and future events that were judged important and emotionally intense. Collectively, these findings provide novel evidence that the direct production of episodic future thoughts is frequent in the word cueing paradigm and often involves the activation of personally significant "memories of the future."

Attachment-related strategies during thought suppression: ironic rebounds and vulnerable self-representations.

PubMed

Mikulincer, Mario; Dolev, Tamar; Shaver, Phillip R

2004-12-01

The authors conducted 2 studies of attachment-related variations in thought suppression. Participants were asked, or not asked, to suppress thoughts about a relationship breakup and then to perform a Stroop task under high or low cognitive load. The dependent variables were the rebound, of previously suppressed separation-related thoughts (Study 1) and the accessibility of self-traits (Study 2). Under low cognitive load, avoidant individuals did not show any rebound of separation-related thoughts and activated positive self-representations. Under high cognitive load, avoidant participants failed to suppress thoughts of separation and were more likely to activate negative self-representations. Attachment anxiety was associated with high activation of negative self-representations and unremitting separation-related thoughts. The results are discussed in terms of the hidden vulnerabilities of avoidant individuals. ((c) 2004 APA, all rights reserved).

Non-erotic thoughts, attentional focus, and sexual problems in a community sample.

PubMed

Nelson, Andrea L; Purdon, Christine

2011-04-01

According to Barlow's model of sexual dysfunction, anxiety in sexual situations leads to attentional focus on sexual performance at the expense of erotic cues, which compromises sexual arousal. This negative experience will enhance anxiety in future sexual situations, and non-erotic thoughts (NETs) relevant to performance will receive attentional priority. Previous research with student samples (Purdon & Holdaway, 2006; Purdon & Watson, 2010) has found that people experience many types of NETs in addition to performance-relevant thoughts, and that, consistent with Barlow's model, the frequency of and anxiety evoked by these thoughts is positively associated with sexual problems. Extending this previous work, the current study found that, in a community sample of women (N = 81) and men (N = 72) in long-term relationships, women were more likely to report body image concerns and external consequences of the sexual activity, while men were more likely to report performance-related concerns. Equally likely among men and women were thoughts about emotional consequences of the sexual activity. Regardless of thought content, experiencing more frequent NETs was associated with more sexual problems in both women and men. Moreover, as per Barlow's model, greater negative affect in anticipation of and during sexual activity predicted greater frequency of NETs and greater anxiety in response to NETs was associated with greater difficulty dismissing the thoughts. However, greater difficulty in refocusing on erotic thoughts during sexual activity uniquely predicted more sexual problems above the frequency and dismissability of NETs. Together, these data support the cognitive interference mechanism implicated by Barlow's causal model of sexual dysfunction and have implications for the treatment of sexual problems.

On Realizing It's Worse than I Thought

ERIC Educational Resources Information Center

Entin, David

2009-01-01

It didn't end with an acceptance letter in the mail. That was the highlight of the high school to college transition, but it wasn't the finish line, far from it. In this essay, the author describes his feelings on transitioning from high school to college. He finally sees that the process is worse than he thought. Because it's not another step in…

Intentions to Maintain Adherence to Mammography

PubMed Central

Bowling, J. Michael; Brewer, Noel T.; Lipkus, Isaac M.; Skinner, Celette Sugg; Strigo, Tara S.; Rimer, Barbara K.

2008-01-01

Abstract Objective Recent attention has focused on moving women from having initial mammograms to maintaining adherence to regular mammography schedules. We examined behavioral intentions to maintain mammography adherence, which include the likelihood of performing a behavior, and implementation intentions, specific action plans to obtain mammograms. Potential predictors were Theory of Planned Behavior constructs, previous barriers, previous mammography maintenance, and age. Methods Respondents were 2062 currently adherent women due for their next mammograms in 3–4 months according to American Cancer Society recommendations for annual screening. Statistical models were used to examine predictors of behavioral and two implementation intentions, including having thought about where women would get their next mammograms and having thought about making appointments. Results With the exception of pros, cons, and subjective norms, all variables predicted behavioral intentions (p ≤ 0.05). Stronger perceived control, previous mammography maintenance, and one barrier (vs. none) predicted being more likely to have thought about where to get their next mammograms. Previous maintenance and no barriers (vs. two) predicted being more likely to have thought about making appointments. Conclusions Our findings suggest that among women currently adherent to mammography, volitional factors, such as barriers, may be better predictors of implementation intentions than motivational factors, such as attitudes. Implementation variables may be useful in understanding how women move from intentions to action. Future research should examine how such factors relate to mammography maintenance behaviors and can be integrated into behavior change interventions. PMID:18657041

Thought Disorder in Preschool Children with Attention Deficit/Hyperactivity Disorder (ADHD).

PubMed

Hutchison, Amanda K; Kelsay, Kimberly; Talmi, Ayelet; Noonan, Kate; Ross, Randal G

2016-08-01

Preschool identification of and intervention for psychiatric symptoms has the potential for lifelong benefits. However, preschool identification of thought disorder, a symptom associated with long term risk for social and cognitive dysfunction, has received little attention with previous work limited to examining preschoolers with severe emotional and behavioral dysregulation. Using story-stem methodology, 12 children with ADHD and 12 children without ADHD, ages 4.0-6.0 years were evaluated for thought disorder. Thought disorder was reliably assessed (Cronbach's alpha = .958). Children with ADHD were significantly more likely than children without ADHD to exhibit thought disorder (75 vs 25 %; Fischer's Exact Test = .0391). Thought disorder can be reliably assessed in preschool children and is present in preschool children with psychiatric illness including preschool children with ADHD. Thought disorder may be identifiable in preschool years across a broad range of psychiatric illnesses and thus may be an appropriate target of intervention.

From intrusive to oscillating thoughts.

PubMed

Peirce, Anne Griswold

2007-10-01

This paper focused on the possibility that intrusive thoughts (ITs) are a form of an evolutionary, adaptive, and complex strategy to prepare for and resolve stressful life events through schema formation. Intrusive thoughts have been studied in relation to individual conditions, such as traumatic stress disorder and obsessive-compulsive disorder. They have also been documented in the average person experiencing everyday stress. In many descriptions of thought intrusion, it is accompanied by thought suppression. Several theories have been put forth to describe ITs, although none provides a satisfactory explanation as to whether ITs are a normal process, a normal process gone astray, or a sign of pathology. There is also no consistent view of the role that thought suppression plays in the process. I propose that thought intrusion and thought suppression may be better understood by examining them together as a complex and adaptive mechanism capable of escalating in times of need. The ability of a biological mechanism to scale up in times of need is one hallmark of a complex and adaptive system. Other hallmarks of complexity, including self-similarity across scales, sensitivity to initial conditions, presence of feedback loops, and system oscillation, are also discussed in this article. Finally, I propose that thought intrusion and thought suppression are better described together as an oscillatory cycle.

Daily spillover from family to work: A test of the work-home resources model.

PubMed

Du, Danyang; Derks, Daantje; Bakker, Arnold B

2018-04-01

The present study examines a mediated moderation model of the day-level effects of family hassles and family-work spillover (affect and cognition) on the relationship between job resources and employees' flourishing at work. Based on the work-home resources model, the authors hypothesized that demands from one domain (family) induce repetitive thoughts or negative feelings about those problems, so that individuals are not able to function optimally and to make full use of contextual resources in the other domain (work). Multilevel analyses of 108 Chinese working parents' 366 daily surveys revealed that the relationship between morning job resources and afternoon flourishing was significantly positive when previous day family hassles were low; the relationship became nonsignificant when previous day family hassles were high. In addition, as predicted, daily rumination also attenuated the relationship between morning job resources and afternoon flourishing, whereas daily affect did not. Finally, the moderating effect of previous day family hassles was mediated by daily rumination. The findings contribute to spillover theories by revealing the roles of affective and cognitive spillover from family to work. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

About various definitions of life.

PubMed

Luisi, P L

1998-10-01

The old question of a definition of minimal life is taken up again at the aim of providing a forum for an updated discussion. Briefly discussed are the reasons why such an attempt has previously encountered scepticism, and why such an attempt should be renewed at this stage of the inquiry on the origin of life. Then some of the definitions of life presently used are cited and briefly discussed, starting with the definition adopted by NASA as a general working definition. It is shown that this is too limited if one wishes to provide a broad encompassing definition, and some extensions of it are presented and discussed. Finally it is shown how the different definitions of life reflect the main schools of thought that presently dominate the field on the origin of life.

The Self-help Online against Suicidal thoughts (SOS) trial: study protocol for a randomized controlled trial.

PubMed

Mühlmann, Charlotte; Madsen, Trine; Hjorthøj, Carsten; Kerkhof, Ad; Nordentoft, Merete; Erlangsen, Annette

2017-01-28

Suicidal thoughts are common, causing distress for millions of people all over the world. However, people with suicidal thoughts might not access support due to financial restraints, stigma or a lack of available treatment offers. Self-help programs provided online could overcome these barriers, and previous efforts show promising results in terms of reducing suicidal thoughts. This study aims to examine the effectiveness of an online self-help intervention in reducing suicidal thoughts among people at risk of suicide. The Danish Self-help Online against Suicidal thoughts (SOS) trial is a partial replication of a previously conducted Dutch trial. A randomized, waiting-list controlled trial with 1:1 allocation ratio will be carried out. A total of 438 people with suicidal thoughts will be recruited from the Danish suicide hotline, The Lifeline's, website and allocated to the intervention condition (N = 219) or the control condition (N = 219). The intervention condition consists of a 6-week, Internet-based self-help therapy intervention. The format of the intervention is self-help, but the participants can be guided by the trial manager. The control condition consists of a waiting-list assignment for 32 weeks. The primary outcomes are frequency and intensity of suicidal thoughts. Secondary outcome measures include depressive symptoms, hopelessness, worrying, quality of life, costs related to health care utilization and production loss. Number of deliberate self-harm episodes, suicides and deaths will, as well as the participant's evaluation of the intervention and the experience of negative effects, be investigated. Assessments will be conducted over the intervention website through self-report questionnaires at baseline, 2 weeks, 4 weeks, 6 weeks and 32 weeks (6 months post intervention). If we find the intervention to be linked to reductions in suicidal thoughts, this will strengthen the evidence that online self-help interventions are relevant tools for people with suicidal thoughts. ClinicalTrials.gov, NCT02872610 . Registered on 9 August 2016.

Unnoticed intrusions: dissociations of meta-consciousness in thought suppression.

PubMed

Baird, Benjamin; Smallwood, Jonathan; Fishman, Daniel J F; Mrazek, Michael D; Schooler, Jonathan W

2013-09-01

The current research investigates the interaction between thought suppression and individuals' explicit awareness of their thoughts. Participants in three experiments attempted to suppress thoughts of a prior romantic relationship and their success at doing so was measured using a combination of self-catching and experience-sampling. In addition to thoughts that individuals spontaneously noticed, individuals were frequently caught engaging in thoughts of their previous partner at experience-sampling probes. Furthermore, probe-caught thoughts were: (i) associated with stronger decoupling of attention from the environment, (ii) more likely to occur under cognitive load, (iii) more frequent for individuals with a desire to reconcile, and (iv) associated with individual differences in the tendency to suppress thoughts. Together, these data suggest that individuals can lack meta-awareness that they have begun to think about a topic they are attempting to suppress, providing novel insight into the cognitive processes that are involved in attempting to control undesired mental states. Copyright © 2013 Elsevier Inc. All rights reserved.

Spatially robust estimates of biological nitrogen (N) fixation imply substantial human alteration of the tropical N cycle

PubMed Central

Sullivan, Benjamin W.; Smith, W. Kolby; Townsend, Alan R.; Nasto, Megan K.; Reed, Sasha C.; Chazdon, Robin L.; Cleveland, Cory C.

2014-01-01

Biological nitrogen fixation (BNF) is the largest natural source of exogenous nitrogen (N) to unmanaged ecosystems and also the primary baseline against which anthropogenic changes to the N cycle are measured. Rates of BNF in tropical rainforest are thought to be among the highest on Earth, but they are notoriously difficult to quantify and are based on little empirical data. We adapted a sampling strategy from community ecology to generate spatial estimates of symbiotic and free-living BNF in secondary and primary forest sites that span a typical range of tropical forest legume abundance. Although total BNF was higher in secondary than primary forest, overall rates were roughly five times lower than previous estimates for the tropical forest biome. We found strong correlations between symbiotic BNF and legume abundance, but we also show that spatially free-living BNF often exceeds symbiotic inputs. Our results suggest that BNF in tropical forest has been overestimated, and our data are consistent with a recent top-down estimate of global BNF that implied but did not measure low tropical BNF rates. Finally, comparing tropical BNF within the historical area of tropical rainforest with current anthropogenic N inputs indicates that humans have already at least doubled reactive N inputs to the tropical forest biome, a far greater change than previously thought. Because N inputs are increasing faster in the tropics than anywhere on Earth, both the proportion and the effects of human N enrichment are likely to grow in the future. PMID:24843146

Mind wandering and the attention network system.

PubMed

Gonçalves, Óscar F; Rêgo, Gabriel; Oliveira-Silva, Patrícia; Leite, Jorge; Carvalho, Sandra; Fregni, Felipe; Amaro, Edson; Boggio, Paulo S

2017-01-01

Attention and mind wandering are often seen as anticorrelated. However, both attention and mind wandering are multi-component processes, and their relationship may be more complex than previously thought. In this study, we tested the interference of different types of thoughts as measured by a Thought Identification Task - TIT (on task thoughts, task related interference thoughts, external distractions, stimulus independent and task unrelated thoughts) on different components of the attention network system - ANT (alerting, orienting, executive). Results show that, during the ANT, individuals were predominantly involved in task related interference thoughts which, along with external distractors, significantly impaired their performance accuracy. However, mind wandering (i.e., stimulus independent and task unrelated thoughts) did not significantly interfere with accuracy in the ANT. No significant relationship was found between type of thoughts and alerting, orienting, or executive effects in the ANT. While task related interference thoughts and external distractions seemed to impair performance on the attention task, mind wandering was still compatible with satisfactory performance in the ANT. The present results confirmed the importance of differentiating type of "out of task" thoughts in studying the relationship between though distractors and attention. Copyright © 2016 Elsevier B.V. All rights reserved.

A hydrogen-rich early Earth atmosphere.

PubMed

Tian, Feng; Toon, Owen B; Pavlov, Alexander A; De Sterck, H

2005-05-13

We show that the escape of hydrogen from early Earth's atmosphere likely occurred at rates slower by two orders of magnitude than previously thought. The balance between slow hydrogen escape and volcanic outgassing could have maintained a hydrogen mixing ratio of more than 30%. The production of prebiotic organic compounds in such an atmosphere would have been more efficient than either exogenous delivery or synthesis in hydrothermal systems. The organic soup in the oceans and ponds on early Earth would have been a more favorable place for the origin of life than previously thought.

Self-handicapping, excuse making, and counterfactual thinking: consequences for self-esteem and future motivation.

PubMed

McCrea, Sean M

2008-08-01

Researchers interested in counterfactual thinking have often found that upward counterfactual thoughts lead to increased motivation to improve in the future, although at the cost of increased negative affect. The present studies suggest that because upward counterfactual thoughts indicate reasons for a poor performance, they can also serve as excuses. In this case, upward counterfactual thoughts should result in more positive self-esteem and reduced future motivation. Five studies demonstrated these effects in the context of self-handicapping. First, upward counterfactual thinking was increased in the presence of a self-handicap. Second, upward counterfactual thoughts indicating the presence of a self-handicap protected self-esteem following failure. Finally, upward counterfactual thoughts that protect self-esteem reduced preparation for a subsequent performance as well as performance itself. These findings suggest that the consequences of upward counterfactuals for affect and motivation are moderated by the goals of the individual as well as the content of the thoughts. (c) 2008 APA, all rights reserved

Mapping racism.

PubMed

Moss, Donald B

2006-01-01

The author uses the metaphor of mapping to illuminate a structural feature of racist thought, locating the degraded object along vertical and horizontal axes. These axes establish coordinates of hierarchy and of distance. With the coordinates in place, racist thought begins to seem grounded in natural processes. The other's identity becomes consolidated, and parochialism results. The use of this kind of mapping is illustrated via two patient vignettes. The author presents Freud's (1905, 1927) views in relation to such a "mapping" process, as well as Adorno's (1951) and Baldwin's (1965). Finally, the author conceptualizes the crucial status of primitivity in the workings of racist thought.

Thought-action fusion in individuals with OCD symptoms.

PubMed

Amir, N; Freshman, M; Ramsey, B; Neary, E; Brigidi, B

2001-07-01

Rachman (Rachman, S. (1993). Obsessions, responsibility, and guilt. Behaviour Research and Therapy, 31, 149-154) suggested that patients with OCD may interpret thoughts as having special importance, thus experiencing thought-action fusion (TAF). Shafran, Thordarson and Rachman (Shafran, R., Thordarson, D. S. & Rachman, S. (1996). Thought-action fusion in obsessive compulsive disorder. Journal of Anxiety Disorders, 710, 379-391) developed a questionnaire (TAF) and found that obsessives scored higher than non-obsessives on the measure. In the current study, we modified the TAF to include a scale that assessed the "likelihood of events happening to others" as well as ratings of the responsibility and cost for having these thoughts. Replicating previous findings, we found that individuals with OC symptoms gave higher ratings to the likelihood of negative events happening as a result of their negative thoughts. Individuals with OC symptoms also rated the likelihood that they would prevent harm by their positive thoughts higher than did individuals without OC symptoms. These results suggest that the role of thought-action fusion in OCs may extend to exaggerated beliefs about thoughts regarding the reduction of harm.

Testing the efficacy of pure versus guided mirror exposure in women with bulimia nervosa: A combination of neuroendocrine and psychological indices.

PubMed

Díaz-Ferrer, Sandra; Rodríguez-Ruiz, Sonia; Ortega-Roldán, Blanca; Moreno-Domínguez, Silvia; Fernández-Santaella, M Carmen

2015-09-01

Body exposure improves body image problems in women with eating disorders. However it has almost always been combined with other interventions. Thus, the efficacy of body exposure alone (i.e., pure exposure) remains largely unclear. We aimed to compare the efficacy of two body exposure techniques through psychological and neuroendocrine indices recorded within and between successive sessions. Twenty-nine women with high body dissatisfaction and diagnosis of bulimia nervosa were randomly assigned to one of two treatment groups: Pure Exposure (n = 14) or Guided Exposure (n = 15). Participants received 6 exposure sessions. After each session, changes in thoughts (positive/negative) and body satisfaction were assessed. Also, we assessed the body discomfort experienced by participants within and between sessions. Finally, the changes in salivary cortisol levels within and between the initial and final treatment sessions were measured. Both groups showed a reduction in negative thoughts and a progressive increase in positive thoughts throughout the treatment. However, the increase in body satisfaction and the reduction in subjective discomfort within the sessions were greater in the pure exposure group. The cortisol levels during the initial and final treatment sessions decreased in both groups. Methodological limitations are reported. These results suggest that pure and guided exposures are effective interventions for improving thoughts and neuroendocrine responses, although pure exposure increased more body satisfaction feelings in bulimic women. Subjective discomfort also showed different patterns of change within and along sessions for each treatment. Reasons for these results are discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.

Neural activity associated with self, other, and object-based counterfactual thinking.

PubMed

De Brigard, Felipe; Nathan Spreng, R; Mitchell, Jason P; Schacter, Daniel L

2015-04-01

Previous research has shown that autobiographical episodic counterfactual thinking-i.e., mental simulations about alternative ways in which one's life experiences could have occurred-engages the brain's default network (DN). However, it remains unknown whether or not the DN is also engaged during impersonal counterfactual thoughts, specifically those involving other people or objects. The current study compares brain activity during counterfactual simulations involving the self, others and objects. In addition, counterfactual thoughts involving others were manipulated in terms of similarity and familiarity with the simulated characters. The results indicate greater involvement of DN during person-based (i.e., self and other) as opposed to object-based counterfactual simulations. However, the involvement of different regions of the DN during other-based counterfactual simulations was modulated by how close and/or similar the simulated character was perceived to be by the participant. Simulations involving unfamiliar characters preferentially recruited dorsomedial prefrontal cortex. Simulations involving unfamiliar similar characters, characters with whom participants identified personality traits, recruited lateral temporal gyrus. Finally, our results also revealed differential coupling of right hippocampus with lateral prefrontal and temporal cortex during counterfactual simulations involving familiar similar others, but with left transverse temporal gyrus and medial frontal and inferior temporal gyri during counterfactual simulations involving either oneself or unfamiliar dissimilar others. These results suggest that different brain mechanisms are involved in the simulation of personal and impersonal counterfactual thoughts, and that the extent to which regions associated with autobiographical memory are recruited during the simulation of counterfactuals involving others depends on the perceived similarity and familiarity with the simulated individuals. Copyright © 2015 Elsevier Inc. All rights reserved.

Patient perception of physician reimbursement in elective shoulder surgery.

PubMed

Nagda, Sameer; Wiesel, Brent; Abboud, Joseph; Salamone, Andrew; Sheth, Neil; Foran, Jared; Garstka, Johnny

2015-01-01

A previous study revealed that patients perceived physician reimbursement to be much higher than current Medicare schedules for hip and knee replacement. The purpose of this study was to evaluate patient perception of surgeon reimbursement for total shoulder replacement (TSA) and rotator cuff repair (RCR). The study surveyed 250 patients. Patients were asked what they believe a surgeon should be reimbursed for performing TSA and RCR. Patients were then asked to estimate what Medicare reimbursed for each of these procedures. We then revealed the Medicare reimbursement rate for TSA and RCR, and patients were asked to comment. Finally, patients were asked whether surgeons with advanced shoulder training should receive additional payments. Patients thought that surgeons should receive $13,178 for TSA and $8459 for RCR. Patients estimated actual Medicare reimbursement was $7177 for TSA and $4692 for RCR. Eighty percent of patients stated that Medicare reimbursement was too low for TSA, 75% thought that payment for RCR was lower than what it should be. Less than 1% of patients felt that it was higher than it should be. A total of 87% of patients thought that surgeons with advanced shoulder training should be reimbursed at a higher rate. Patients perceived the values of TSA and RCR were much higher than current Medicare schedules. This is in agreement with prior surveys. Continued decreases in Medicare reimbursements may force surgeons to not participate in Medicare and create a potential access issue. Further investigation should focus on identifying how many surgeons may opt out. Copyright © 2015 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

Neural activity associated with self, other, and object-based counterfactual thinking

PubMed Central

De Brigard, Felipe; Spreng, R. Nathan; Mitchell, Jason P.; Schacter, Daniel L.

2016-01-01

Previous research has shown that autobiographical episodic counterfactual thinking—i.e., mental simulations about alternative ways in which one’s life experiences could have occurred—engages the brain’s default network (DN). However, it remains unknown whether or not the DN is also engaged during impersonal counterfactual thoughts, specifically those involving other people or objects. The current study compares brain activity during counterfactual simulations involving the self, others and objects. In addition, counterfactual thoughts involving others were manipulated in terms of similarity and familiarity with the simulated characters. The results indicate greater involvement of DN during person-based (i.e., self and other) as opposed to object-based counterfactual simulations. However, the involvement of different regions of the DN during other-based counterfactual simulations was modulated by how close and/or similar the simulated character was perceived to be by the participant. Simulations involving unfamiliar characters preferentially recruited dorsomedial prefrontal cortex. Simulations involving unfamiliar similar characters, characters with whom participants identified personality traits, recruited lateral temporal gyrus. Finally, our results also revealed differential coupling of right hippocampus with lateral prefrontal and temporal cortex during counterfactual simulations involving familiar similar others, but with left transverse temporal gyrus and medial frontal and inferior temporal gyri during counterfactual simulations involving either oneself or unfamiliar dissimilar others. These results suggest that different brain mechanisms are involved in the simulation of personal and impersonal counterfactual thoughts, and that the extent to which regions associated with autobiographical memory are recruited during the simulation of counterfactuals involving others depends on the perceived similarity and familiarity with the simulated individuals. PMID:25579447

Culture evolves

PubMed Central

Whiten, Andrew; Hinde, Robert A.; Laland, Kevin N.; Stringer, Christopher B.

2011-01-01

Culture pervades human lives and has allowed our species to create niches all around the world and its oceans, in ways quite unlike any other primate. Indeed, our cultural nature appears so distinctive that it is often thought to separate humanity from the rest of nature and the Darwinian forces that shape it. A contrary view arises through the recent discoveries of a diverse range of disciplines, here brought together to illustrate the scope of a burgeoning field of cultural evolution and to facilitate cross-disciplinary fertilization. Each approach emphasizes important linkages between culture and evolutionary biology rather than quarantining one from the other. Recent studies reveal that processes important in cultural transmission are more widespread and significant across the animal kingdom than earlier recognized, with important implications for evolutionary theory. Recent archaeological discoveries have pushed back the origins of human culture to much more ancient times than traditionally thought. These developments suggest previously unidentified continuities between animal and human culture. A third new array of discoveries concerns the later diversification of human cultures, where the operations of Darwinian-like processes are identified, in part, through scientific methods borrowed from biology. Finally, surprising discoveries have been made about the imprint of cultural evolution in the predispositions of human minds for cultural transmission. PMID:21357216

The role of gist and verbatim memory in complex decision making: Explaining the unconscious-thought effect.

PubMed

Abadie, Marlène; Waroquier, Laurent; Terrier, Patrice

2017-05-01

Previous research showed that the unconscious-thought effect , which refers to an improvement in complex decision making following a distraction period, was moderated by the presentation format of pieces of information about different options. The aim of the current study was to replicate this finding and further examine the memory representations underlying decision making following a distraction or a deliberation period. Results showed that, when the information was presented blocked per option, participants were better able to differentiate the best option from the others after a distraction period than immediately after the information presentation or after a deliberation period. In addition, distracted participants retrieved more gist representations of the options when the information was presented per option. By contrast, participants were better able to differentiate the best option from the others after a deliberation period when the information was presented per attribute. Participants who deliberated also retrieved more verbatim representations when the information was presented per attribute. Finally, mediation analyses indicated that the accuracy of the evaluations of the options depends on gist memory when distracted but on verbatim memory when deliberating. These findings suggest that the effectiveness of distraction or deliberation depends on the memory representations of the different options. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

The evolutionary dynamics of receptor binding avidity in influenza A: a mathematical model for a new antigenic drift hypothesis

PubMed Central

Yuan, Hsiang-Yu; Koelle, Katia

2013-01-01

The most salient feature of influenza evolution in humans is its antigenic drift. This process is characterized by structural changes in the virus's B-cell epitopes and ultimately results in the ability of the virus to evade immune recognition and thereby reinfect previously infected hosts. Until recently, amino acid substitutions in epitope regions of the viral haemagglutinin were thought to be positively selected for their ability to reduce antibody binding and therefore were thought to be responsible for driving antigenic drift. However, a recent hypothesis put forward by Hensley and co-workers posits that cellular receptor binding avidity is the dominant phenotype under selection, with antigenic drift being a side effect of these binding avidity changes. Here, we present a mathematical formulation of this new antigenic drift model and use it to show how rates of antigenic drift depend on epidemiological parameters. We further use the model to evaluate how two different vaccination strategies can impact antigenic drift rates and ultimately disease incidence levels. Finally, we discuss the assumptions present in the model formulation, predictions of the model, and future work that needs to be done to determine the consistency of this hypothesis with known patterns of influenza's genetic and antigenic evolution. PMID:23382426

Data-Driven Design: Learning from Student Experiences and Behaviors

NASA Astrophysics Data System (ADS)

Horodyskyj, L.; Mead, C.; Buxner, S.; Semken, S. C.; Anbar, A. D.

2015-12-01

Good instructors know that lessons and courses change over time. Limitations in time and data often prevent instructors from making changes that will most benefit their students. For example, in traditional in-person classrooms an instructor may only have access to the final product of a student's thought processes (such as a term paper, homework assignment, or exam). The thought processes that lead to a given answer are opaque to the instructor, making future modifications to course content an exercise in trial-and-error and instinct. Modern online intelligent tutoring systems can provide insight into a student's behavior, providing transparency to a previously opaque process and providing the instructor with better information for course modification. Habitable Worlds is an introductory level online-only astrobiology lab course that has been offered at Arizona State University since Fall 2011. The course is built and offered through an intelligent tutoring system, Smart Sparrow's Adaptive eLearning Platform, which provides in-depth analytics that allow the instructor to investigate detailed student behavior, from time spent on question to number of attempts to patterns of answers. We will detail the process we employ of informed modification of course content, including time and trial comparisons between semesters, analysis of submitted answers, analysis of alternative learning pathways taken, and A/B testing.

Identification of Eye-Specific Domains and Their Relation to Callosal Connections in Primary Visual Cortex of Long Evans Rats.

PubMed

Laing, R J; Turecek, J; Takahata, T; Olavarria, J F

2015-10-01

Ocular dominance columns (ODCs) exist in many primates and carnivores, but it is believed that they do not exist in rodents. Using a combination of transneuronal tracing, in situ hybridization for Zif268 and electrophysiological recordings, we show that inputs from both eyes are largely segregated in the binocular region of V1 in Long Evans rats. We also show that, interposed between this binocular region and the lateral border of V1, there lies a strip of cortex that is strongly dominated by the contralateral eye. Finally, we show that callosal connections colocalize primarily with ipsilateral eye domains in the binocular region and with contralateral eye input in the lateral cortical strip, mirroring the relationship between patchy callosal connections and specific sets of ODCs described previously in the cat. Our results suggest that development of cortical modular architecture is more conserved among rodents, carnivores, and primates than previously thought. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Forever Alone? Testing Single Eccentric Planetary Systems for Multiple Companions

NASA Astrophysics Data System (ADS)

Wittenmyer, Robert A.; Wang, Songhu; Horner, Jonathan; Tinney, C. G.; Butler, R. P.; Jones, H. R. A.; O'Toole, S. J.; Bailey, J.; Carter, B. D.; Salter, G. S.; Wright, D.; Zhou, Ji-Lin

2013-09-01

Determining the orbital eccentricity of an extrasolar planet is critically important for understanding the system's dynamical environment and history. However, eccentricity is often poorly determined or entirely mischaracterized due to poor observational sampling, low signal-to-noise, and/or degeneracies with other planetary signals. Some systems previously thought to contain a single, moderate-eccentricity planet have been shown, after further monitoring, to host two planets on nearly circular orbits. We investigate published apparent single-planet systems to see if the available data can be better fit by two lower-eccentricity planets. We identify nine promising candidate systems and perform detailed dynamical tests to confirm the stability of the potential new multiple-planet systems. Finally, we compare the expected orbits of the single- and double-planet scenarios to better inform future observations of these interesting systems.

Bone Marrow Matters

ERIC Educational Resources Information Center

Dunne, Mark; Maklad, Rania; Heaney, Emma

2014-01-01

As a final-year student teacher specialising in primary science, Emma Heaney faced the challenge of having to plan, organise, and conduct a small-scale, classroom-based research project. She had to teach about bones in the final block practice session and thought it would be a good idea to bring in some biological specimens obtained from the local…

Two Arts. Revision and What It Leaves behind

ERIC Educational Resources Information Center

Booten, Kyle

2012-01-01

Inspired by an experience of teaching the drafts of Elizabeth Bishop's "One Art", this article rereads the drafts as far more than imperfect precursors to the final poem. The drafts have their own prosodic features and poetic logic, one that values and enacts a vertiginous dilation of thought, expression and memory. The final version of…

What’s the Harm in Asking about Suicidal Ideation?

PubMed Central

Mathias, Charles W.; Furr, R. Michael; Sheftall, Arielle H.; Hill-Kapturczak, Nathalie; Crum, Paige; Dougherty, Donald M.

2013-01-01

Both researchers and oversight committees share concerns about patient safety in the study-related assessment of suicidality. However, concern about assessing suicidal thoughts can be a barrier to the development of empirical evidence that informs research on how to safely conduct these assessments. A question has been raised if asking about suicidal thoughts can result in iatrogenic increases of such thoughts, especially among at-risk samples. The current study repeatedly tested suicidal ideation at 6-month intervals for up to 2-years. Suicidal ideation was measured with the Suicidal Ideation Questionnaire Junior, and administered to adolescents who had previously received inpatient psychiatric care. Change in suicidal ideation was tested using several analytic techniques, each of which pointed to a significant decline in suicidal ideation in the context of repeated assessment. This and previous study outcomes suggest that asking an at-risk population about suicidal ideation is not associated with subsequent increases in suicidal ideation. PMID:22548324

An unusual birthmark case thought to be linked to a person who had previously died.

PubMed

Keil, H H; Tucker, J B

2000-12-01

The following case report describes a Burmese subject with an unusual birthmark and birth defects thought by local people to be linked to events surrounding the death of his mother's first husband. The nature of the link is explored, including how the assumption of a linkage could have led to subsequent events.

The Role of Gist and Verbatim Memory in Complex Decision Making: Explaining the Unconscious-Thought Effect

ERIC Educational Resources Information Center

Abadie, Marlène; Waroquier, Laurent; Terrier, Patrice

2017-01-01

Previous research showed that the "unconscious-thought effect", which refers to an improvement in complex decision making following a distraction period, was moderated by the presentation format of pieces of information about different options. The aim of the current study was to replicate this finding and further examine the memory…

When self-destructive thoughts flash through the mind: Failure to meet standards affects the accessibility of suicide-related thoughts.

PubMed

Chatard, Armand; Selimbegović, Leila

2011-04-01

When individuals realize that they fail to attain important standards or expectations, they may be motivated to escape the self, which could lead thoughts of suicide to become more accessible. Six studies examined this hypothesis, mainly derived from escape theory (Baumeister, 1990). The results indicated that whenever individuals realize that they fail to attain an important standard, they experience increased accessibility of suicide-related thoughts (Studies 1-6). In line with the idea that such effects reflect motivations to escape from negative self-awareness, they were especially pronounced when associated with high levels of self-consciousness and escapist motivations (Study 1) and with a large discrepancy between self and standards (Studies 2-4). Moreover, failure to attain standards increased suicide-thought accessibility along with the desire for an altered state of consciousness (Study 5). Finally, increases in suicide-thought accessibility after failure were associated with simultaneous increases in accessibility of general concepts related to escape (Study 6). Implications of these findings for escape and terror management theories are discussed.

The relation between language, culture, and thought.

PubMed

Imai, Mutsumi; Kanero, Junko; Masuda, Takahiko

2016-04-01

The relationship between culture, language, and thought has long been one of the most important topics for those who wish to understand the nature of human cognition. This issue has been investigated for decades across a broad range of research disciplines. However, there has been scant communication across these different disciplines, a situation largely arising through differences in research interests and discrepancies in the definitions of key terms such as 'culture,' 'language,' and 'thought.' This article reviews recent trends in research on the relation between language, culture and thought to capture how cognitive psychology and cultural psychology have defined 'language' and 'culture,' and how this issue was addressed within each research discipline. We then review recent research conducted in interdisciplinary perspectives, which directly compared the roles of culture and language. Finally, we highlight the importance of considering the complex interplay between culture and language to provide a comprehensive picture of how language and culture affect thought. Copyright © 2015 Elsevier Ltd. All rights reserved.

Does unconscious thought improve complex decision making?

PubMed

Rey, Arnaud; Goldstein, Ryan M; Perruchet, Pierre

2009-05-01

In a recent study, Dijksterhuis et al. (Science 311:1005, 2006) reported that participants were better at solving complex decisions after a period of unconscious thought relative to a period of conscious thought. They interpreted their results as an existence proof of powerful unconscious deliberation mechanisms. In the present report, we used a similar experimental design with an additional control, immediate condition, and we observed that participants produced as good (and even descriptively better) decisions in this condition than in the "unconscious" one, hence challenging the initial interpretation of the authors. However, we still obtained lower performances in the "conscious" relative to the "immediate" condition, suggesting that the initial result of Dijksterhuis et al. was not due to the action of powerful unconscious thought processes, but to the apparent disadvantage of further conscious processing. We provide an explanation for this observation on the basis of current models of decision making. It is finally concluded that the benefit of unconscious thought in complex decision making is still a controversial issue that should be considered cautiously.

Heuristics guide cooperative behaviors in public goods game

NASA Astrophysics Data System (ADS)

Wang, Yongjie; Chen, Tong

2015-12-01

In public goods game (PGG), player's cooperative behavior is not pure economical rationality, but social preference and prosocial intuition play extremely important roles as well. Social preference and prosocial intuition can be guided by heuristics from one's neighbors in daily life. To better investigate the impacts of heuristics on the evolution of cooperation, four types of agents are introduced into our spatial PGG. Through numerical simulations, results show that the larger percentages of cooperators with independent thought, the easier emergence and maintenance of collective cooperative behaviors. Additionally, we find that differentia heuristic capability has great effect on the equilibrium of PGG. Cooperation can be obviously promoted, when heuristic capability of cooperators with independent thought is stronger than that of defectors with independent thought. Finally, we observe that cooperators with independent thought and defectors with independent thought are favorable for the formation of some high quality clusters, which can resist the invasion between each other. Our work may help us understand more clearly the mechanism of cooperation in real world.

The prospective relationship between sleep problems and suicidal behavior in the National Longitudinal Study of Adolescent Health.

PubMed

Wong, Maria M; Brower, Kirk J

2012-07-01

Previous research has found a longitudinal relationship between sleep problems and suicidal behavior while controlling for depression and other important covariates in a high risk sample of adolescents and controls. In this paper, we replicated this longitudinal relationship in a national sample and examined whether the relationship was partially mediated by depression, alcohol-related problems and other drug use. Study participants were 6504 adolescents from the National Longitudinal Study of Adolescent Health (ADD HEALTH). In bivariate analyses, sleep problems (i.e., having trouble falling asleep or staying asleep) at Wave 1 were associated with suicidal thoughts and suicide attempts at Waves 1, 2, and 3 (W1, 2 and 3). In multivariate analyses, controlling for depression, alcohol problems, illicit drug use, and important covariates such as gender, age, and chronic health problems, sleep problems at a previous wave predicted suicidal thoughts and suicide attempts at a subsequent wave. In mediation analyses, W2 depression significantly mediated the effect of W1 sleep problems on W3 suicide thoughts. Moreover, W2 suicidal thoughts also significantly mediated the effect of W1 sleep problems on W3 suicidal attempts. Sleep problems appear to be a robust predictor of subsequent suicidal thoughts and attempts in adolescence and young adulthood. Having trouble falling sleeping or staying asleep had both direct and indirect effects (via depression and suicidal thoughts) on suicidal behavior. Future research could determine if early intervention with sleep disturbances reduces the risk for suicidality in adolescents and young adults. Copyright © 2012 Elsevier Ltd. All rights reserved.

The relationship between religion and thought-action fusion: use of an in vivo paradigm.

PubMed

Berman, Noah C; Abramowitz, Jonathan S; Pardue, Caleb M; Wheaton, Michael G

2010-07-01

Research has demonstrated that higher levels of religiosity are positively correlated with thought-action fusion (TAF), a set of cognitive biases found to be associated with obsessive-compulsive symptoms. However, previous studies have exclusively relied on a nomothetic approach to measuring TAF using a single self-report instrument, the thought-action fusion scale. The current study examined the relationship between religiosity and TAF using an in vivo behaviorally-based assessment in which participants thought about and wrote down thoughts of negative events involving loved ones. Forty-three highly religious Protestant Christians were compared to 30 Atheists/Agnostics on their in vivo ratings of anxiety, estimates of likelihood, and moral wrongness related to the negative thoughts. Results indicated that compared to the non-religious participants, those who were highly religious believed that writing and thinking about the negative events was more morally wrong and increased the likelihood of the event. Results are discussed in terms of the potential relationship between certain religious teachings and TAF-related beliefs about the importance, significance, and influence of thoughts. Copyright 2010 Elsevier Ltd. All rights reserved.

An Analysis of the Balance of Management, Technical and Leadership Progression through the Three USAF Officer Tiers

DTIC Science & Technology

2007-03-01

schools of thought on the relationship between management and leadership traits among successful CEO’s, Generals, politicians, entrepreneurs, etc… First...al. 2005:6). Finally, there is a school of thought that management and leadership are two distinct entities, but extremely successful people happen...doesn’t mean they can play basketball and a person having basketball skills doesn’t make them tall. However, the NBA is predominantly filled with

Cognitions as mediators in the relationship between self-compassion and affect

PubMed Central

Arimitsu, Kohki; Hofmann, Stefan G.

2014-01-01

Previous studies suggest that self-compassion is related to numerous facets of mental health, but the role of cognitions in this relationship remains unknown. To examine the mediating role of cognitions in the relationship between self-compassion and anxiety, depression, and life satisfaction when controlling for self-esteem in Japanese people, we conducted two studies. Study 1 (N = 231) examined the relationship between self-compassion and affect by modeling negative automatic thoughts as a mediator; Study 2 (N = 233) tested whether positive and negative automatic thoughts meditate this relationship. Results suggested that both self-compassion and self-esteem increased positive automatic thoughts and decreased trait anxiety, whereas only self-esteem increased life satisfaction and decreased depression directly. Positive automatic thoughts increased life satisfaction and decreased depression and trait anxiety, and positive automatic thoughts mediated the relationship between self-compassion and negative affect. These findings suggest that both positive and negative automatic thoughts mediate the relationship between self-compassion and affect in Japanese people. PMID:25395717

The history of sociology as a field of research and some recent trends in Brazilian social thought.

PubMed

Maia, João Marcelo Ehlert

2017-01-01

The article lays the foundation for a dialog between scholars of Brazilian social thought and historians of sociology as a discipline. In order to achieve this objective, I analyze recent developments in the field of the history of sociology, highlighting the incorporation of historiographic methods and the emergence of a transnational approach, which points toward a global history of the discipline. I criticize the Eurocentric limits of this field and argue that recent research trends in the area of Brazilian social thought can help overcome this limitation. Finally, I briefly analyze the obstacles that impede this dialog and indicate possible strategies for overcoming them.

Intrusive images and intrusive thoughts as different phenomena: two experimental studies.

PubMed

Hagenaars, Muriel A; Brewin, Chris R; van Minnen, Agnes; Holmes, Emily A; Hoogduin, Kees A L

2010-01-01

According to the dual representation theory of PTSD, intrusive trauma images and intrusive verbal thoughts are produced by separate memory systems. In a previous article it was shown that after watching an aversive film, participants in non-movement conditions reported more intrusive images than participants in a free-to-move control condition (Hagenaars, Van Minnen, Holmes, Brewin, & Hoogduin, 2008). The present study investigates whether the experimental conditions of the Hagenaars et al. study had a different effect on intrusive thoughts than on intrusive images. Experiment 2 further investigated the image-thoughts distinction by manipulating stimulus valence (trauma film versus neutral film) and assessing the subsequent development of intrusive images and thoughts. In addition, both experiments studied the impact of peri-traumatic emotions on subsequent intrusive images and thoughts frequency across conditions. Results showed that experimental manipulations (non-movement and trauma film) caused higher levels of intrusive images relative to control conditions (free movement and neutral film) but they did not affect intrusive thoughts. Peri-traumatic anxiety and horror were associated with subsequent higher levels of intrusive images, but not intrusive thoughts. Correlations were inconclusive for anger and sadness. The results suggest intrusive images and thoughts can be manipulated independently and as such can be considered different phenomena.

Suicidal behavior among homeless people in Japan.

PubMed

Okamura, Tsuyoshi; Ito, Kae; Morikawa, Suimei; Awata, Shuichi

2014-04-01

The purpose of this study is to investigate the frequency and correlates of suicidal behavior among homeless people in Japan. A face-to-face survey was conducted in two districts of Tokyo, Japan, with 423 subjects who resided on streets and riversides and in urban parks and stations (street homeless) or who were residents of shelters, cheap hotels, or welfare homes for homeless people (sheltered homeless). When questioned about suicidal ideation in the previous 2 weeks, 51 subjects (12.2% of valid responses) had a recurring wish to die, 29 (6.9%) had frequent thoughts of suicide, and 22 (5.3%) had made suicide plans. In addition, 11 (2.9%) subjects had attempted suicide in the previous 2 weeks and 74 (17.7%) reported that they had ever attempted suicide. In univariate logistic regression analyses, street homelessness, lack of perceived emotional social support, poor subjective health perception, visual impairment, pain, insomnia, poor mental well-being, and current depression were significantly associated with recurrent thoughts of suicide in the previous 2 weeks. Among these, current depression had the greatest significance. In multivariate logistic regression analyses after controlling for depression, street homelessness and lack of perceived emotional social support were significantly associated with recurrent thoughts of suicide in the previous 2 weeks. Comprehensive interventions including housing and social support as well as mental health services might be crucial as effective strategies for suicide prevention among homeless people.

Revisiting the Relationship between Individual Differences in Analytic Thinking and Religious Belief: Evidence That Measurement Order Moderates Their Inverse Correlation.

PubMed

Finley, Anna J; Tang, David; Schmeichel, Brandon J

2015-01-01

Prior research has found that persons who favor more analytic modes of thought are less religious. We propose that individual differences in analytic thought are associated with reduced religious beliefs particularly when analytic thought is measured (hence, primed) first. The current study provides a direct replication of prior evidence that individual differences in analytic thinking are negatively related to religious beliefs when analytic thought is measured before religious beliefs. When religious belief is measured before analytic thinking, however, the negative relationship is reduced to non-significance, suggesting that the link between analytic thought and religious belief is more tenuous than previously reported. The current study suggests that whereas inducing analytic processing may reduce religious belief, more analytic thinkers are not necessarily less religious. The potential for measurement order to inflate the inverse correlation between analytic thinking and religious beliefs deserves additional consideration.

Revisiting the Relationship between Individual Differences in Analytic Thinking and Religious Belief: Evidence That Measurement Order Moderates Their Inverse Correlation

PubMed Central

Finley, Anna J.; Tang, David; Schmeichel, Brandon J.

2015-01-01

Prior research has found that persons who favor more analytic modes of thought are less religious. We propose that individual differences in analytic thought are associated with reduced religious beliefs particularly when analytic thought is measured (hence, primed) first. The current study provides a direct replication of prior evidence that individual differences in analytic thinking are negatively related to religious beliefs when analytic thought is measured before religious beliefs. When religious belief is measured before analytic thinking, however, the negative relationship is reduced to non-significance, suggesting that the link between analytic thought and religious belief is more tenuous than previously reported. The current study suggests that whereas inducing analytic processing may reduce religious belief, more analytic thinkers are not necessarily less religious. The potential for measurement order to inflate the inverse correlation between analytic thinking and religious beliefs deserves additional consideration. PMID:26402334

The role of thought suppression in the relation between mindfulness meditation and alcohol use

PubMed Central

Bowen, Sarah; Witkiewitz, Katie; Dillworth, Tiara M.; Marlatt, G. Alan

2007-01-01

Previous studies have demonstrated that attempts to suppress thoughts about using substances may actually lead to increases in substance use. Vipassana, a mindfulness meditation practice, emphasizes acceptance, rather than suppression, of unwanted thoughts. Bowen and colleagues (2006) studied the effects of a Vipassana course on substance use and in an incarcerated population, showing significant reductions in substance use among the Vipassana group as compared to a treatment as usual control condition (Bowen, Witkiewitz, Dillworth, Chawla, Simpson, Ostafin, et al., 2006). The current study further examines the mediating effects of thought suppression in the relationship between participation in the course and subsequent alcohol use in an incarcerated population. Those who participated in the course reported significant decreases in avoidance of thoughts when compared to controls. The decrease in avoidance partially mediated effects of the course on post-release alcohol use and consequences. PMID:17300875

Predictors of Mental Health Symptoms, Automatic Thoughts, and Self-Esteem Among University Students.

PubMed

Hiçdurmaz, Duygu; İnci, Figen; Karahan, Sevilay

2017-01-01

University youth is a risk group regarding mental health, and many mental health problems are frequent in this group. Sociodemographic factors such as level of income and familial factors such as relationship with father are reported to be associated with mental health symptoms, automatic thoughts, and self-esteem. Also, there are interrelations between mental health problems, automatic thoughts, and self-esteem. The extent of predictive effect of each of these variables on automatic thoughts, self-esteem, and mental health symptoms is not known. We aimed to determine the predictive factors of mental health symptoms, automatic thoughts, and self-esteem in university students. Participants were 530 students enrolled at a university in Turkey, during 2014-2015 academic year. Data were collected using the student information form, the Brief Symptom Inventory, the Automatic Thoughts Questionnaire, and the Rosenberg Self-Esteem Scale. Mental health symptoms, self-esteem, perception of the relationship with the father, and level of income as a student significantly predicted automatic thoughts. Automatic thoughts, mental health symptoms, participation in family decisions, and age had significant predictive effects on self-esteem. Finally, automatic thoughts, self-esteem, age, and perception of the relationship with the father had significant predictive effects on mental health symptoms. The predictive factors revealed in our study provide important information to practitioners and researchers by showing the elements that need to be screened for mental health of university students and issues that need to be included in counseling activities.

Body Image in Dyadic and Solitary Sexual Desire: The Role of Encoding Style and Distracting Thoughts.

PubMed

Dosch, Alessandra; Ghisletta, Paolo; Van der Linden, Martial

2016-01-01

This study explored the link between body image and desire to engage in sexual activity (dyadic and solitary desire) in adult women living in a long-term couple relationship. Moreover, it considered two psychological factors that may underlie such a link: the occurrence of body-related distracting thoughts during sexual activity and encoding style (i.e., the tendency to rely on preexisting internal schemata versus external information at encoding). A total of 53 women (29 to 47 years old) in heterosexual relationships completed questionnaires assessing sexual desire (dyadic, solitary), body image, body-related distracting thoughts during sexual activity, and encoding style. Results showed that poor body image was associated with low dyadic and solitary sexual desire. Body-related distracting thoughts during sexual activity mediated the link between body image and solitary (but not dyadic) sexual desire. Finally, the mediation of body-related distracting thoughts between body image and solitary sexual desire was moderated by encoding style. A negative body image promoted the occurrence of body-related distracting thoughts during sexual activity, especially in internal encoders. Our study highlights the importance of body image, distracting thoughts, and encoding style in women's solitary sexuality and suggests possible factors that may reduce the impact of those body-related factors in dyadic sexual desire.

Perceptions of a fluid consensus: uniqueness bias, false consensus, false polarization, and pluralistic ignorance in a water conservation crisis.

PubMed

Monin, Benoît; Norton, Michael I

2003-05-01

A 5-day field study (N = 415) during and right after a shower ban demonstrated multifaceted social projection and the tendency to draw personality inferences from simple behavior in a time of drastic consensus change. Bathers thought showering was more prevalent than did non-bathers (false consensus) and respondents consistently underestimated the prevalence of the desirable and common behavior--be it not showering during the shower ban or showering after the ban (uniqueness bias). Participants thought that bathers and non-bathers during the ban differed greatly in their general concern for the community, but self-reports demonstrated that this gap was illusory (false polarization). Finally, bathers thought other bathers cared less than they did, whereas non-bathers thought other non-bathers cared more than they did (pluralistic ignorance). The study captures the many biases at work in social perception in a time of social change.

Think, blink or sleep on it? The impact of modes of thought on complex decision making.

PubMed

Newell, Ben R; Wong, Kwan Yao; Cheung, Jeremy C H; Rakow, Tim

2009-04-01

This paper examines controversial claims about the merit of "unconscious thought" for making complex decisions. In four experiments, participants were presented with complex decisions and were asked to choose the best option immediately, after a period of conscious deliberation, or after a period of distraction (said to encourage "unconscious thought processes"). In all experiments the majority of participants chose the option predicted by their own subjective attribute weighting scores, regardless of the mode of thought employed. There was little evidence for the superiority of choices made "unconsciously", but some evidence that conscious deliberation can lead to better choices. The final experiment suggested that the task is best conceptualized as one involving "online judgement" rather than one in which decisions are made after periods of deliberation or distraction. The results suggest that we should be cautious in accepting the advice to "stop thinking" about complex decisions.

Demonstration of cathode emittance dominated high bunch charge beams in a DC gun-based photoinjector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gulliford, Colwyn, E-mail: cg248@cornell.edu; Bartnik, Adam, E-mail: acb20@cornell.edu; Bazarov, Ivan

We present the results of transverse emittance and longitudinal current profile measurements of high bunch charge (≥100 pC) beams produced in the DC gun-based Cornell energy recovery linac photoinjector. In particular, we show that the cathode thermal and core beam emittances dominate the final 95% and core emittances measured at 9–9.5 MeV. Additionally, we demonstrate excellent agreement between optimized 3D space charge simulations and measurement, and show that the quality of the transverse laser distribution limits the optimal simulated and measured emittances. These results, previously thought achievable only with RF guns, demonstrate that DC gun based photoinjectors are capable of deliveringmore » beams with sufficient single bunch charge and beam quality suitable for many current and next generation accelerator projects such as Energy Recovery Linacs and Free Electron Lasers.« less

Splanchnic preganglionic neurons in man. III. Morphometry of myelinated fibers of rami communicantes.

PubMed

Low, P A; Dyck, P J

1978-01-01

The myelinated fiber (MF) composition of T6-T8 Rami Communicantes were obtained in 9 healthy persons of various ages. The textbook picture that distal rami (DR) contain all of the myelinated fibers and therefore are white, while proximal rami (PR) contain none of them and therefore are grey must be modified. We found that DR usually contained abundant MFs and that PR concordance was found between segmental numbers of intermediolateral nuclei cytons, ventral root small myelinated fibers (SMFs), and rami total small MFs to suggest that both rami probably contain the distal myelinated axons of preganglionic autonomic fibers. Finally, there was an attrition of total MFs of rami with age, similar to what we had previously found for ILC cytons and for root SMFs. The decrease in number of pre-ganglionic autonomic neurons with age is thought to be of sufficient magnitude to account for the dysautonomia of the elderly.

Root decisions.

PubMed

Hodge, Angela

2009-06-01

Root systems have recognizable developmental plans when grown in solution or agar; however, these plans often must be modified to cope with the prevailing conditions in the soil environment such as the avoidance of obstacles and the exploitation of nutrient-rich patches or water zones. The modular structure of roots enables them to respond to their environment, and roots are very adaptive at modifying growth throughout the root system to concentrate their efforts in the areas that are the most profitable. Roots also form associations with microorganisms as a strategy to enhance resource capture. However, while the responses of roots in nutrient patches are well-recognized, overall 'rules of response' and variation in strategy among plant species that can be applied in a number of different environments are still lacking. Finally, there is increasing evidence that root-root interactions are much more sophisticated than previously thought, and the evidence for roots to identify self from non-self roots will be briefly discussed.

Avian Models for Human Cognitive Neuroscience: A Proposal.

PubMed

Clayton, Nicola S; Emery, Nathan J

2015-06-17

Research on avian cognitive neuroscience over the past two decades has revealed the avian brain to be a better model for understanding human cognition than previously thought, despite differences in the neuroarchitecture of avian and mammalian brains. The brain, behavior, and cognition of songbirds have provided an excellent model of human cognition in one domain, namely learning human language and the production of speech. There are other important behavioral candidates of avian cognition, however, notably the capacity of corvids to remember the past and plan for the future, as well as their ability to think about another's perspective, and physical reasoning. We review this work and assess the evidence that the corvid brain can support such a cognitive architecture. We propose potential applications of these behavioral paradigms for cognitive neuroscience, including recent work on single-cell recordings and neuroimaging in corvids. Finally, we discuss their impact on understanding human developmental cognition. Copyright © 2015 Elsevier Inc. All rights reserved.

Epidemiological and clinical features of three clustered cases co-infected with Lyme disease and rickettsioses.

PubMed

Xuefei, D; Qin, H; Xiaodi, G; Zhen, G; Wei, L; Xuexia, H; Jiazhen, G; Xiuping, F; Meimei, T; Jingshan, Z; Yunru, L; Xiaoling, F; Kanglin, W; Xingwang, L

2013-11-01

Lyme disease and rickettsioses are two common diseases in China. However, the concomitant occurrence of both diseases in a single individual has been reported infrequently in literature. We reported three related female patients admitted at Beijing Ditan Hospital from October to December 2010. They had similar epidemiological histories. At the beginning, they only got a single diagnosis, respectively, but after specific screenings, the final diagnoses were made. Because arthropods can harbour more than one disease-causing agent, patients can be infected with more than one pathogen at the same time, so the possibility of co-infection could be higher than what was thought previously. These observations suggested that clinicians should enhance the complete screening of arthropod-related infectious diseases so as to make an accurate diagnosis and to avoid diagnostic errors. © 2012 Blackwell Verlag GmbH.

Does Leaders' Health (and Work-Related Experiences) Affect their Evaluation of Followers' Stress?

PubMed

Giorgi, Gabriele; Mancuso, Serena; Fiz Perez, Francisco Javier; Montani, Francesco; Courcy, Francois; Arcangeli, Giulio

2015-09-01

Stressed workers suffer from severe health problems which appear to have increased. Poor leadership is especially considered a source of stress. Indeed, supervisors might perceive their subordinates to be similar to them as far as stress is concerned and this might more widespread in organizations than previously thought. The present research investigates the relationships between leaders' health, in terms of work-related stress, mental health, and workplace bullying and their evaluation of subordinates' stress. Five regression models were formulated to test our hypothesis. This is a cross-sectional study among 261 Italian leaders, using supervisor self-assessment and leaders' assessments of their subordinates. Leaders' health was related to their evaluation of staff stress. Job demand, lack of job control, and lack of support by colleagues and supervisors evaluated in their subordinates were particularly associated with the leaders' own health. Implications for developing healthy leaders are finally discussed.

The global transmission network of HIV-1.

PubMed

Wertheim, Joel O; Leigh Brown, Andrew J; Hepler, N Lance; Mehta, Sanjay R; Richman, Douglas D; Smith, Davey M; Kosakovsky Pond, Sergei L

2014-01-15

Human immunodeficiency virus type 1 (HIV-1) is pandemic, but its contemporary global transmission network has not been characterized. A better understanding of the properties and dynamics of this network is essential for surveillance, prevention, and eventual eradication of HIV. Here, we apply a simple and computationally efficient network-based approach to all publicly available HIV polymerase sequences in the global database, revealing a contemporary picture of the spread of HIV-1 within and between countries. This approach automatically recovered well-characterized transmission clusters and extended other clusters thought to be contained within a single country across international borders. In addition, previously undescribed transmission clusters were discovered. Together, these clusters represent all known modes of HIV transmission. The extent of international linkage revealed by our comprehensive approach demonstrates the need to consider the global diversity of HIV, even when describing local epidemics. Finally, the speed of this method allows for near-real-time surveillance of the pandemic's progression.

After a dozen years of progress the origin of angiosperms is still a great mystery.

PubMed

Frohlich, Michael W; Chase, Mark W

2007-12-20

Here we discuss recent advances surrounding the origin of angiosperms. Putatively primitive characters are now much better understood because of a vastly improved understanding of angiosperm phylogenetics, and recent discoveries of fossil flowers have provided an increasingly detailed picture of early diversity in the angiosperms. The 'anthophyte theory', the dominant concept of the 1980s and 1990s, has been eclipsed; Gnetales, previously thought to be closest to the angiosperms, are related instead to other extant gymnosperms, probably most closely to conifers. Finally, new theories of flower origins have been proposed based on gene function, duplication and loss, as well as on morphology. Further studies of genetic mechanisms that control reproductive development in seed plants provide a most promising avenue for further research, including tests of these recent theories. Identification of fossils with morphologies that convincingly place them close to angiosperms could still revolutionize understanding of angiosperm origins.

Sedna Orbit Animation

NASA Technical Reports Server (NTRS)

2004-01-01

This animation shows the location of the newly discovered planet-like object, dubbed 'Sedna,' in relation to the rest of the solar system. Starting at the inner solar system, which includes the orbits of Mercury, Venus, Earth, and Mars (all in yellow), the view pulls away through the asteroid belt and the orbits of the outer planets beyond (green). Pluto and the distant Kuiper Belt objects are seen next until finally Sedna comes into view. As the field widens the full orbit of Sedna can be seen along with its current location. Sedna is nearing its closest approach to the Sun; its 10,000 year orbit typically takes it to far greater distances. Moving past Sedna, what was previously thought to be the inner edge of the Oort cloud appears. The Oort cloud is a spherical distribution of cold, icy bodies lying at the limits of the Sun's gravitational pull. Sedna's presence suggests that this Oort cloud is much closer than scientists believed.

Does Leaders' Health (and Work-Related Experiences) Affect their Evaluation of Followers' Stress?

PubMed Central

Giorgi, Gabriele; Mancuso, Serena; Fiz Perez, Francisco Javier; Montani, Francesco; Courcy, Francois; Arcangeli, Giulio

2015-01-01

Background Stressed workers suffer from severe health problems which appear to have increased. Poor leadership is especially considered a source of stress. Indeed, supervisors might perceive their subordinates to be similar to them as far as stress is concerned and this might more widespread in organizations than previously thought. Methods The present research investigates the relationships between leaders' health, in terms of work-related stress, mental health, and workplace bullying and their evaluation of subordinates' stress. Five regression models were formulated to test our hypothesis. This is a cross-sectional study among 261 Italian leaders, using supervisor self-assessment and leaders' assessments of their subordinates. Results Leaders' health was related to their evaluation of staff stress. Job demand, lack of job control, and lack of support by colleagues and supervisors evaluated in their subordinates were particularly associated with the leaders' own health. Conclusion Implications for developing healthy leaders are finally discussed. PMID:26929835

EVERY INTERACTING DOUBLE WHITE DWARF BINARY MAY MERGE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shen, Ken J.

2015-05-20

Interacting double white dwarf (WD) binaries can give rise to a wide variety of astrophysical outcomes ranging from faint thermonuclear and Type Ia supernovae to the formation of neutron stars and stably accreting AM Canum Venaticorum systems. One key factor affecting the final outcome is whether mass transfer remains dynamically stable or instead diverges, leading to the tidal disruption of the donor and the merger of the binary. It is typically thought that for low ratios of the donor mass to the accretor mass, mass transfer remains stable, especially if accretion occurs via a disk. In this Letter, we examinemore » low mass ratio double WD binaries and find that the initial phase of hydrogen-rich mass transfer leads to a classical nova-like outburst on the accretor. Dynamical friction within the expanding nova shell shrinks the orbit and causes the mass transfer rate to increase dramatically above the accretor's Eddington limit, possibly resulting in a binary merger. If the binary survives the first hydrogen-rich nova outbursts, dynamical friction within the subsequent helium-powered nova shells pushes the system even more strongly toward merger. While further calculations are necessary to confirm this outcome for the entire range of binaries previously thought to be dynamically stable, it appears likely that most, if not all, interacting double WD binaries will merge during the course of their evolution.« less

New features of mitochondrial DNA replication system in yeast and man.

PubMed

Lecrenier, N; Foury, F

2000-04-04

In this review, we sum up the research carried out over two decades on mitochondrial DNA (mtDNA) replication, primarily by comparing this system in Saccharomyces cerevisiae and Homo sapiens. Brief incursions into systems of other organisms have also been achieved when they provide new information.S. cerevisiae and H. sapiens mitochondrial DNA (mtDNA) have been thought for a long time to share closely related architecture and replication mechanisms. However, recent studies suggest that mitochondrial genome of S. cerevisiae may be formed, at least partially, from linear multimeric molecules, while human mtDNA is circular. Although several proteins involved in the replication of these two genomes are very similar, divergences are also now increasingly evident. As an example, the recently cloned human mitochondrial DNA polymerase beta-subunit has no counterpart in yeast. Yet, yeast Abf2p and human mtTFA are probably not as closely functionally related as thought previously. Some mtDNA metabolism factors, like DNA ligases, were until recently largely uncharacterized, and have been found to be derived from alternative nuclear products. Many factors involved in the metabolism of mitochondrial DNA are linked through genetic or biochemical interconnections. These links are presented on a map. Finally, we discuss recent studies suggesting that the yeast mtDNA replication system diverges from that observed in man, and may involve recombination, possibly coupled to alternative replication mechanisms like rolling circle replication.

Space Radiation Effects on Electronics: Simple Concepts and New Challenges

NASA Technical Reports Server (NTRS)

LaBel, Kenneth A.

2004-01-01

This viewgraph presentation covers the following topics: 1) The Space Radiation Environment; 2) The Effects on Electronics; 3) The Environment in Action; 4) NASA Approaches to Commercial Electronics; 5) Final Thoughts.

The relationship between parents' and children's automatic thoughts in a college student sample.

PubMed

Donnelly, Reesa; Renk, Kimberly; Sims, Valerie K; McGuire, Jack

2011-04-01

Research demonstrates the importance of early social interactions in the development of schemas and automatic thoughts. It does not appear, however, that the existing research examines intergenerational correlations in automatic thoughts. As a result, this study explores the relationship between the automatic thoughts of parents and those of their college-age children in a sample of 252 college students and their mothers and fathers. Results of this study suggest that there are significant relationships between parents' and college students' positive automatic thoughts. Different trends by gender also are noted in the relationships among variables for male and female college students with their mothers and fathers. Further, mothers' positive ATs predicted the positive ATs of their college students, with mothers' ratings of their own communication with their college students mediating partially this relationship. Finally, college students' anxiety and self-esteem is predicted significantly by their mothers' anxiety and self-esteem (respectively) as well as their own positive and negative ATs. These findings suggest the possibility that ATs play a role in the intergenerational transmission of certain domains of psychological functioning.

Bromamine Decomposition Revisited: A Holistic Approach for Analyzing Acid and Base Catalysis Kinetics.

PubMed

Wahman, David G; Speitel, Gerald E; Katz, Lynn E

2017-11-21

Chloramine chemistry is complex, with a variety of reactions occurring in series and parallel and many that are acid or base catalyzed, resulting in numerous rate constants. Bromide presence increases system complexity even further with possible bromamine and bromochloramine formation. Therefore, techniques for parameter estimation must address this complexity through thoughtful experimental design and robust data analysis approaches. The current research outlines a rational basis for constrained data fitting using Brønsted theory, application of the microscopic reversibility principle to reversible acid or base catalyzed reactions, and characterization of the relative significance of parallel reactions using fictive product tracking. This holistic approach was used on a comprehensive and well-documented data set for bromamine decomposition, allowing new interpretations of existing data by revealing that a previously published reaction scheme was not robust; it was not able to describe monobromamine or dibromamine decay outside of the conditions for which it was calibrated. The current research's simplified model (3 reactions, 17 constants) represented the experimental data better than the previously published model (4 reactions, 28 constants). A final model evaluation was conducted based on representative drinking water conditions to determine a minimal model (3 reactions, 8 constants) applicable for drinking water conditions.

Homicidal ideation in family carers of people with dementia.

PubMed

O'Dwyer, Siobhan T; Moyle, Wendy; Taylor, Tara; Creese, Jennifer; Zimmer-Gembeck, Melanie J

2016-11-01

Family carers of people with dementia have higher than average rates of suicidal ideation, but there has been no research on homicidal ideation in this population. The aim of this study was to explore thoughts of homicide in family carers of people with dementia. A descriptive qualitative approach was taken. Twenty-one Australian carers (7 men, 14 women) participated in individual, in-depth interviews and the transcripts were analysed thematically. Seven themes were identified in the data - active thoughts of homicide; understanding homicidal thoughts in others; passive thoughts of death; euthanasia; homicidal thoughts in other caregiving situations; abuse; and disclosing thoughts of harm. Two of the 21 participants had actively contemplated the homicide of their care recipient, four expressed a passive desire for the care recipient's death, and four reported physically or verbally abusing the care recipient. Only one carer had previously disclosed these experiences. Homicidal ideation is a real and significant phenomenon among family carers of people with dementia. Service providers and health professionals are encouraged to identify and support carers contemplating homicide, but to do so in a way that recognises the broader social context of carer burden.

[Is it Possible to Experiment with Thought? Ernst Mach's Notion of Thought Experiment and its Pedagogical Context around 1900. ].

PubMed

Bauer, Julian

2015-03-01

Is it Possible to Experiment with Thought? Ernst Mach's Notion of Thought Experiment and its Pedagogical Context around 1900. The article tries to establish the crucial importance of the pedagogical dimension of Ernst Mach's ideas on experimenting with thought. The focus on contemporary pedagogics demonstrates, first, that Mach's didactic approach to physics is part of a much broader stream of pedagogical writings that transcends national and disciplinary borders and comprises a diversity of authors, e.g. Wilhelm Jerusalem, William James or Alfred N. Whitehead; second, that the much-heralded controversy between Mach and the French philosopher of science Pierre Duhem about thought experiments does not only revolve around epistemological issues but rather stems from their antagonist vision of teaching physics; and finally, third, that G. Stanley Hall's psychogenetic theory of pedagogics bears a strong resemblance with the evolutionary naturalism of Machian epistemology and helps explaining key tenets of Mach's conception of thought experiment. By establishing a broad convergence between the work of all these authors despite their different academic upbringing, background and nationality the article argues for a complex and historically fine-grained vision of the relations between natural, social and human sciences going beyond dichotomies like 'Erklären' and 'Verstehen' or the 'Two Cultures'. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Suppression, accessibility of death-related thoughts, and cultural worldview defense: exploring the psychodynamics of terror management.

PubMed

Arndt, J; Greenberg, J; Solomon, S; Pyszczynski, T; Simon, L

1997-07-01

Previous research has shown that after a mortality-salience (MS) treatment, death thought accessibility and worldview defense are initially low and then increase after a delay, suggesting that a person's initial response to conscious thoughts of mortality is to actively suppress death thoughts. If so, then high cognitive load, by disrupting suppression efforts, should lead to immediate increases in death thought accessibility and cultural worldview defense. Studies 1 and 2 supported this reasoning. Specifically, Study 1 replicated the delayed increase in death accessibility after MS among low cognitive load participants but showed a reversed pattern among participants under high cognitive load. Study 2 showed that, unlike low cognitive load participants, high cognitive load participants exhibited immediate increase in pro-American bias after MS. Study 3 demonstrated that worldview defense in response to MS reduces the delayed increase in death accessibility. Implications of these findings for understanding both terror management processes and psychological defense in general are discussed.

If only I had taken my usual route…: age-related differences in counter-factual thinking.

PubMed

Horhota, Michelle; Mienaltowski, Andrew; Blanchard-Fields, Fredda

2012-01-01

Previous research suggests that young adults can shift between rational and experiential modes of thinking when forming social judgments. The present study examines whether older adults demonstrate this flexibility in thinking. Young and older adults completed an If-only task adapted from Epstein, Lipson, and Huh's (1992 , Journal of Personality and Social Psychology, 62, 328) examination of individuals' ability to adopt rational or experiential modes of thought while making a judgment about characters who experience a negative event that could have been avoided. Consistent with our expectations for their judgments of the characters, young adults shifted between experiential and rational modes of thought when instructed to do so. Conversely, regardless of the mode of thought being used or the order with which they adopted the different modes of thought (i.e., shifting from experiential to rational in Study 1 and from rational to experiential in Study 2), older adults consistently offered judgments and justifications that reflected a preference for experiential-based thought.

Objectification of people and thoughts: An attitude change perspective.

PubMed

Briñol, Pablo; Petty, Richard E; Belding, Jennifer

2017-06-01

Many objectification phenomena can be understood from a mind-body dualism perspective in which the more people focus on their bodies, the less they focus on their minds. Instead of viewing mind and body in opposition to each other, we advocate for a more reciprocal view in which mind and body work in conjunction. Consistent with an integrated mind-body approach, we begin our review by describing research on embodied persuasion revealing that focusing on our own body can reduce but also increase thinking (elaboration), as well as affecting the use of thoughts in forming evaluations (validation). Next, we extend our integrated view to a new domain and suggest that physical objects can influence thoughts and that one's thoughts can also be objectified. The first portion of this section focuses on research on enclothed cognition revealing that wearing physical objects can operate through the same processes of elaboration (increasing and decreasing thinking) and validation (increasing and decreasing thought usage) as the body. The second portion reveals that thoughts can be understood and treated as if they were physical objects affecting evaluative processes by influencing elaboration and validation processes. The final section provides some practical guidance relevant to campaigns designed to reduce the objectification of women and the infrahumanization of stigmatized groups. © 2017 The British Psychological Society.

Taboo thoughts and doubt/checking

PubMed Central

Pinto, Anthony; Eisen, Jane L.; Mancebo, Maria C.; Greenberg, Benjamin D.; Stout, Robert L.; Rasmussen, Steven A.

2007-01-01

The purpose of this report was to improve upon earlier factor analyses of obsessive-compulsive disorder (OCD) symptom categories by minimizing the heterogeneity in the aggressive obsessions category. An exploratory factor analysis was conducted on data from 293 adults with primary OCD. The resulting five factors (Symmetry/Ordering, Hoarding, Doubt/Checking, Contamination/Cleaning, and Taboo Thoughts) are phenomenologically more homogeneous than prior category-based factors and are consistent with those derived in previous item-level analyses. PMID:17368563

Enhancing Propriospinal Relays to Improve Functional Recovery After SCI

DTIC Science & Technology

2017-10-01

injury to the spinal cord. We have completed experiments for subtask 1 – 4 of specific aim 1 and subtasks 1 for specific aim 2. This Aim 2 of the...previously observed PAP2 to induce robust regeneration in a dorsal hemisection model and thought it might enhance regeneration and sprouting after the more...spontaneous recovery is often observed after incomplete injuries, leading to partial recovery over time. Spontaneous recovery is thought to be

Thoughts on Cultural Revolution and Comparative Studies

ERIC Educational Resources Information Center

Lawson, Robert F.

1973-01-01

Author attempted to move from interpretations, which are sometimes indistinguishable from motivations, to the actual social meaning of appeals for cultural revolution, and finally to the question of education as a component of generalized change processes. (Author/RK)

Assurance Against Radiation Effects on Electronics

NASA Technical Reports Server (NTRS)

LaBel, Kenneth A.

2004-01-01

Contents include the following: The Space Radiation Environment. The Effects on Electronics. The Environment in Action. NASA Approaches to Commercial Electronics: the mission mix, flight projects, and proactive research. Final Thoughts: atomic interactions, direct ionization, interaction with nucleus.

Mind-wandering and task stimuli: Stimulus-dependent thoughts influence performance on memory tasks and are more often past- versus future-oriented.

PubMed

Maillet, David; Seli, Paul; Schacter, Daniel L

2017-07-01

Although many studies have indicated that participants frequently mind-wander during experimental tasks, relatively little research has examined the extent to which such thoughts are triggered by task stimuli (stimulus-dependent thoughts; SDTs) versus internally triggered (stimulus-independent thoughts; SITs). In the current experiment, we assessed differences in the frequency and characteristics of SDTs and SITs, as well as their associations with subsequent memory in young adults. Whereas frequency of SDTs (but not SITs) increased in a task with more meaningful stimuli, frequency of SITs (but not SDTs) increased in an easier task. Furthermore, only SDTs were more likely to be past- versus future-oriented. Finally, frequency and vividness of SDTs during a shallow, but not a deep, incidental encoding task both correlated with later memory performance for word stimuli. These results suggest that SDTs differ from SITs in several important ways. Copyright © 2017 Elsevier Inc. All rights reserved.

An Experimental Comparison of Techniques: Cognitive Defusion, Cognitive Restructuring, and in-vivo Exposure for Social Anxiety.

PubMed

Barrera, Terri L; Szafranski, Derek D; Ratcliff, Chelsea G; Garnaat, Sarah L; Norton, Peter J

2016-03-01

One of the primary differences between Cognitive Behavioral Therapy (CBT) and Acceptance and Commitment Therapy (ACT) for anxiety is the approach to managing negative thoughts. CBT focuses on challenging the accuracy of dysfunctional thoughts through cognitive restructuring exercises, whereas ACT attempts to foster acceptance of such thoughts through cognitive defusion exercises. Previous research suggests that both techniques reduce the distress associated with negative thoughts, though questions remain regarding the benefit of these techniques above and beyond exposure to feared stimuli. In the present study, we conducted a brief experimental intervention to examine the utility of cognitive defusion + in-vivo exposure, cognitive restructuring + in-vivo exposure, and in-vivo exposure alone in reducing the impact of negative thoughts in patients with social anxiety disorder. All participants completed a brief public speaking exposure and those in the cognitive conditions received training in the assigned cognitive technique. Participants returned a week later to complete a second exposure task and self-report measures. All three conditions resulted in similar decreases in discomfort related to negative thoughts. ANOVA models failed to find an interaction between change in accuracy or importance and assignment to condition in predicting decreased distress of negative thoughts. These preliminary results suggest that changes in perceived importance and accuracy of negative thoughts may not be the mechanisms by which cognitive defusion and cognitive restructuring affect distress in the short-term.

How Do Thoughts, Emotions, and Decisions Align? A New Way to Examine Theory of Mind in Middle Childhood and Beyond

PubMed Central

Lagattuta, Kristin Hansen

2016-01-01

The current study examined 4- to 10-year-olds’ and adults’ (N = 280) tendency to connect people’s thoughts, emotions, and decisions into valence-matched mental state triads (thought valence = emotion valence = decision valence; such as, anticipate something bad + feel worried + avoid) and valence-matched mental state dyads (thought-emotion, thought-decision, and emotion-decision). Participants heard vignettes about focal characters who re-encountered individuals who had previously harmed them twice, helped them twice, or both harmed and helped them. Baseline trials involved no past experience. Children and adults predicted the focal characters’ thoughts (anticipate something good or bad), emotions (feel happy or worried), and decisions (go near or stay away). Results showed significant increases between 4 and 10 years in the formation of valence-matched mental state triads and dyads, with thoughts and emotions most often aligned by valence. We also documented age-related improvement in awareness that uncertain situations elicit less valence-consistent mental states than more certain situations, with females expecting weaker coherence among characters’ thoughts, emotions, and decisions than males. Controlling for age and sex, individuals with stronger executive function (working memory and inhibitory control) predicted more valence-aligned mental states. These findings add to the emerging literature on development and individual differences in children’s reasoning about mental states and emotions during middle childhood and beyond. PMID:27017060

Examination of a cognitive model of stress, burnout, and intention to resign for Japanese nurses.

PubMed

Ohue, Takashi; Moriyama, Michiko; Nakaya, Takashi

2011-06-01

A reduction in burnout is required to decrease the voluntary turnover of nurses. This study was carried out with the aim of establishing a cognitive model of stress, burnout, and intention to resign for nurses. A questionnaire survey was administered to 336 nurses (27 male and 309 female) who had worked for ≤5 years at a hospital with multiple departments. The survey included an evaluation of burnout (Maslach Burnout Inventory), stress (Nursing Job Stressor Scale), automatic thoughts (Automatic Thoughts Questionnaire-Revised), and irrational beliefs (Japanese Irrational Belief Test), in addition to the intention to resign. The stressors that affected burnout in the nurses included conflict with other nursing staff, nursing role conflict, qualitative workload, quantitative workload, and conflict with patients. The irrational beliefs that were related to burnout included dependence, problem avoidance, and helplessness. In order to examine the automatic thoughts affecting burnout, groups with low and high negative automatic thoughts and low and high positive automatic thoughts were established. A two-way ANOVA showed a significant interaction of these factors with emotional exhaustion, but no significant interaction with depersonalization and a personal sense of accomplishment. Only the major effect was significant. The final model showed a process of "stressor → irrational beliefs → negative automatic thoughts/positive automatic thoughts → burnout". In addition, a relationship between burnout and an intention to resign was shown. These results suggest that stress and burnout in nurses might be prevented and that the number of nurses who leave their position could be decreased by changing irrational beliefs to rational beliefs, decreasing negative automatic thoughts, and facilitating positive automatic thoughts. © 2010 The Authors. Japan Journal of Nursing Science © 2010 Japan Academy of Nursing Science.

A deconstruction of the I-M-L commitment segmentation of forest recreationists

Treesearch

James D. Absher; Gerard T. Kyle

2007-01-01

Previous work has established the general utility of segmenting forest recreationists according to their commitment profiles into Indifferents, Moderates, and Loyalists (IML) groups. Observed differences between these segments suggest that place identity and affect are more central to management than previously thought. This study extends this finding through the use...

Rated Temperature Of Silver/Zinc Batteries Is Increased

NASA Technical Reports Server (NTRS)

Hill, Derek P.

1992-01-01

Report shows silver-zinc batteries of specific commercial type (28 V, 20 A*h, Eagle-Picher Battery MAR 4546-5) operated safely at higher temperature than previously thought possible. Batteries operated to 239 degrees F (115 degrees C) without going into sustained thermal runaway. Operated 49 degrees F (27 degrees C) above previous maximum.

Site selection for MSFC operational tests of solar heating and cooling systems

NASA Technical Reports Server (NTRS)

1978-01-01

The criteria, methodology, and sequence aspects of the site selection process are presented. This report organized the logical thought process that should be applied to the site selection process, but final decisions are highly selective.

Electron mobility in mercury cadmium telluride

NASA Technical Reports Server (NTRS)

Patterson, James D.

1988-01-01

A previously developed program, which includes all electronic interactions thought to be important, does not correctly predict the value of electron mobility in mercury cadmium telluride particularly near room temperature. Part of the reason for this discrepancy is thought to be the way screening is handled. It seems likely that there are a number of contributors to errors in the calculation. The objective is to survey the calculation, locate reasons for differences between experiment and calculation, and suggest improvements.

Daydream Believer: Rumination, Self-Reflection and the Temporal Focus of Mind Wandering Content.

PubMed

Shrimpton, Daisy; McGann, Deborah; Riby, Leigh M

2017-11-01

Current research into mind-wandering is beginning to acknowledge that this process is one of heterogeneity. Following on from previous findings highlighting the role of self-focus during mind wandering, the present study aimed to examine individual differences in rumination and self-reflection and the impact such styles of self-focus may have on mind-wandering experiences. Thirty-three participants were required to complete the Sustained Attention Response Task (SART), aimed at inducing mind-wandering episodes, whilst also probing the content of thought in terms of temporal focus. Self-report questionnaires were also administered after the SART to measure dispositional differences in style and beliefs regarding mind-wandering and assessments of individual differences in rumination and self-reflection. Those individuals with reflective self-focus showed a strong positive association with positive and constructive thoughts. Critically, ruminative self-focus was positively associated with a tendency for the mind to wander towards anguished fantasies, failures and aggression, but it was also positively associated with positive and constructive thoughts. Furthermore, while dispositional differences in self-focus showed no relationship with the temporal perspective of thoughts when probed during a cognitive task, performance on the task itself was related to whether participants were thinking about the past, present or future during that activity. Such findings are discussed in line with previous research, and provide a further step towards accounting for the heterogeneous nature of mind-wandering.

Daydream Believer: Rumination, Self-Reflection and the Temporal Focus of Mind Wandering Content

PubMed Central

Shrimpton, Daisy; McGann, Deborah; Riby, Leigh M.

2017-01-01

Current research into mind-wandering is beginning to acknowledge that this process is one of heterogeneity. Following on from previous findings highlighting the role of self-focus during mind wandering, the present study aimed to examine individual differences in rumination and self-reflection and the impact such styles of self-focus may have on mind-wandering experiences. Thirty-three participants were required to complete the Sustained Attention Response Task (SART), aimed at inducing mind-wandering episodes, whilst also probing the content of thought in terms of temporal focus. Self-report questionnaires were also administered after the SART to measure dispositional differences in style and beliefs regarding mind-wandering and assessments of individual differences in rumination and self-reflection. Those individuals with reflective self-focus showed a strong positive association with positive and constructive thoughts. Critically, ruminative self-focus was positively associated with a tendency for the mind to wander towards anguished fantasies, failures and aggression, but it was also positively associated with positive and constructive thoughts. Furthermore, while dispositional differences in self-focus showed no relationship with the temporal perspective of thoughts when probed during a cognitive task, performance on the task itself was related to whether participants were thinking about the past, present or future during that activity. Such findings are discussed in line with previous research, and provide a further step towards accounting for the heterogeneous nature of mind-wandering. PMID:29358989

How Personality Affects Vulnerability among Israelis and Palestinians following the 2009 Gaza Conflict

PubMed Central

Canetti, Daphna; Kimhi, Shaul; Hanoun, Rasmiyah; Rocha, Gabriel A.; Galea, Sandro; Morgan, Charles A.

2016-01-01

Can the onset of PTSD symptoms and depression be predicted by personality factors and thought control strategies? A logical explanation for the different mental health outcomes of individuals exposed to trauma would seem to be personality factors and thought control strategies. Trauma exposure is necessary but not sufficient for the development of PTSD. To this end, we assess the role of personality traits and coping styles in PTSD vulnerability among Israeli and Palestinian students amid conflict. We also determine whether gender and exposure level to trauma impact the likelihood of the onset of PTSD symptoms. Five questionnaires assess previous trauma, PTSD symptoms, demographics, personality factors and thought control strategies, which are analyzed using path analysis. Findings show that the importance of personality factors and thought control strategies in predicting vulnerability increases in the face of political violence: the higher stress, the more important the roles of personality and thought control strategies. Thought control strategies associated with introverted and less emotionally stable personality-types correlate positively with higher levels of PTSD symptoms and depression, particularly among Palestinians. By extension, because mental health is key to reducing violence in the region, PTSD reduction in conflict zones warrants rethinking. PMID:27391240

How Personality Affects Vulnerability among Israelis and Palestinians following the 2009 Gaza Conflict.

PubMed

Canetti, Daphna; Kimhi, Shaul; Hanoun, Rasmiyah; Rocha, Gabriel A; Galea, Sandro; Morgan, Charles A

2016-01-01

Can the onset of PTSD symptoms and depression be predicted by personality factors and thought control strategies? A logical explanation for the different mental health outcomes of individuals exposed to trauma would seem to be personality factors and thought control strategies. Trauma exposure is necessary but not sufficient for the development of PTSD. To this end, we assess the role of personality traits and coping styles in PTSD vulnerability among Israeli and Palestinian students amid conflict. We also determine whether gender and exposure level to trauma impact the likelihood of the onset of PTSD symptoms. Five questionnaires assess previous trauma, PTSD symptoms, demographics, personality factors and thought control strategies, which are analyzed using path analysis. Findings show that the importance of personality factors and thought control strategies in predicting vulnerability increases in the face of political violence: the higher stress, the more important the roles of personality and thought control strategies. Thought control strategies associated with introverted and less emotionally stable personality-types correlate positively with higher levels of PTSD symptoms and depression, particularly among Palestinians. By extension, because mental health is key to reducing violence in the region, PTSD reduction in conflict zones warrants rethinking.

"I remember thinking …": Neural activity associated with subsequent memory for stimulus-evoked internal mentations.

PubMed

Gilead, Michael; Liberman, Nira; Maril, Anat

2014-01-01

Conscious thought involves an interpretive inner monologue pertaining to our waking experiences. Previous studies focused on the mechanisms that allow us to remember externally presented stimuli, but the neurobiological basis of the ability to remember one's internal mentations remains unknown. In order to investigate this question, we presented participants with sentences and scanned their neural activity using functional magnetic resonance imaging (fMRI) as they incidentally produced spontaneous internal mentations. After the scan, we presented the sentences again and asked participants to describe the specific thoughts they had during the initial presentation of each sentence. We categorized experimental trials for each participant according to whether they resulted in subsequently reported internal mentations or not. The results show that activation within classic language processing areas was associated with participants' ability to recollect their thoughts. Activation within mostly right lateralized and medial "default-mode network" regions was associated with not reporting such thoughts.

Effects of realism on extended violent and nonviolent video game play on aggressive thoughts, feelings, and physiological arousal.

PubMed

Barlett, Christopher P; Rodeheffer, Christopher

2009-01-01

Previous research has shown that playing violent video game exposure can increase aggressive thoughts, aggressive feelings, and physiological arousal. This study compared the effects that playing a realistic violent, unrealistic violent, or nonviolent video game for 45 min has on such variables. For the purpose of this study, realism was defined as the probability of seeing an event in real life. Participants (N=74; 39 male, 35 female) played either a realistic violent, unrealistic violent, or nonviolent video game for 45 min. Aggressive thoughts and aggressive feelings were measured four times (every 15 min), whereas arousal was measured continuously. The results showed that, though playing any violent game stimulated aggressive thoughts, playing a more realistic violent game stimulated significantly more aggressive feelings and arousal over the course of play. Copyright 2009 Wiley-Liss, Inc.

Re-Evaluation of the Role of Starch in Gravitropic Sensing

NASA Technical Reports Server (NTRS)

Sack, Fred D.

1998-01-01

Plant organs grow toward or away from gravity as a way to orient those organs for optimizing growth. Starch has long been thought to be important in sensing the direction of the g-vector in gravitropism, but that hypothesis has also evoked controversy. We have previously shown that starch-deficient mutants of Arabidopsis (TC7) and Nicotiana (NS458) are impaired in their gravitropism. While this suggests that starch is not necessary for reduced gravitropism, it also indicates that the mass of the starch contributes to sensing when present and thus is necessary for full gravitropic sensitivity. The research supported by this grant focused on three related projects, (1) the effect of light on hypocotyl gravitropism in NS458, (2) the effects of root phototropism on measurements of gravitropic sensitivity, and (3) the effects of starch overproduction on sedimentation and gravitropism. Collectively, our results provide additional strong support for the importance of starch in gravitropic sensing. First, by accounting for negative phototropism in roots of two starchless mutants of Arabidopsis we have established that these mutants are much less sensitive to gravity than previously thought. This work also demonstrates the importance of designing experimental protocols that remove the influence of root phototropism on measuring root gravitropism. Second, light apparently promotes gravitropism in starch-deficient Nicotiana hypocotyls by increasing the trace amounts of starch in the plastids, by inducing limited plastid sedimentation and thus by presumably increasing the signal provided by plastid mass. And finally, we show that excess starch in Arabidopsis seedlings has little effect on gravitropic sensitivity implying that the sensing system is already saturated. However, in light-grown stems where this mutation results in starch accumulation and where the wild-type practically lacks starch in the sensing cells, the mutant is much more sensitive than the wild-type again showing that the loss of starch depresses gravity sensing.

Evolution of the 3-hydroxypropionate bicycle and recent transfer of anoxygenic photosynthesis into the Chloroflexi

DOE PAGES

Shih, Patrick M.; Ward, Lewis M.; Fischer, Woodward W.

2017-09-18

We report various lines of evidence from both comparative biology and the geologic record make it clear that the biochemical machinery for anoxygenic photosynthesis was present on early Earth and provided the evolutionary stock from which oxygenic photosynthesis evolved ca. 2.3 billion years ago. However, the taxonomic identity of these early anoxygenic phototrophs is uncertain, including whether or not they remain extant. Several phototrophic bacterial clades are thought to have evolved before oxygenic photosynthesis emerged, including the Chloroflexi, a phylum common across a wide range of modern environments. Although Chloroflexi have traditionally been thought to be an ancient phototrophic lineage,more » genomics has revealed a much greater metabolic diversity than previously appreciated. Here, using a combination of comparative genomics and molecular clock analyses, we show that phototrophic members of the Chloroflexi phylum are not particularly ancient, having evolved well after the rise of oxygen (ca. 867 million years ago), and thus cannot be progenitors of oxygenic photosynthesis. Similarly, results show that the carbon fixation pathway that defines this clade—the 3-hydroxypropionate bicycle—evolved late in Earth history as a result of a series of horizontal gene transfer events, explaining the lack of geological evidence for this pathway based on the carbon isotope record. Finally, these results demonstrate the role of horizontal gene transfer in the recent metabolic innovations expressed within this phylum, including its importance in the development of a novel carbon fixation pathway.« less

Evolution of the 3-hydroxypropionate bicycle and recent transfer of anoxygenic photosynthesis into the Chloroflexi

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shih, Patrick M.; Ward, Lewis M.; Fischer, Woodward W.

We report various lines of evidence from both comparative biology and the geologic record make it clear that the biochemical machinery for anoxygenic photosynthesis was present on early Earth and provided the evolutionary stock from which oxygenic photosynthesis evolved ca. 2.3 billion years ago. However, the taxonomic identity of these early anoxygenic phototrophs is uncertain, including whether or not they remain extant. Several phototrophic bacterial clades are thought to have evolved before oxygenic photosynthesis emerged, including the Chloroflexi, a phylum common across a wide range of modern environments. Although Chloroflexi have traditionally been thought to be an ancient phototrophic lineage,more » genomics has revealed a much greater metabolic diversity than previously appreciated. Here, using a combination of comparative genomics and molecular clock analyses, we show that phototrophic members of the Chloroflexi phylum are not particularly ancient, having evolved well after the rise of oxygen (ca. 867 million years ago), and thus cannot be progenitors of oxygenic photosynthesis. Similarly, results show that the carbon fixation pathway that defines this clade—the 3-hydroxypropionate bicycle—evolved late in Earth history as a result of a series of horizontal gene transfer events, explaining the lack of geological evidence for this pathway based on the carbon isotope record. Finally, these results demonstrate the role of horizontal gene transfer in the recent metabolic innovations expressed within this phylum, including its importance in the development of a novel carbon fixation pathway.« less

Lack of α-Xylosidase Activity in Arabidopsis Alters Xyloglucan Composition and Results in Growth Defects1[W][OA

PubMed Central

Sampedro, Javier; Pardo, Brenda; Gianzo, Cristina; Guitián, Esteban; Revilla, Gloria; Zarra, Ignacio

2010-01-01

Xyloglucan is the main hemicellulose in the primary cell walls of most seed plants and is thought to play a role in regulating the separation of cellulose microfibrils during growth. Xylose side chains block the degradation of the backbone, and α-xylosidase activity is necessary to remove them. Two Arabidopsis (Arabidopsis thaliana) mutant lines with insertions in the α-xylosidase gene AtXYL1 were characterized in this work. Both lines showed a reduction to undetectable levels of α-xylosidase activity against xyloglucan oligosaccharides. This reduction resulted in the accumulation of XXXG and XXLG in the liquid growth medium of Atxyl1 seedlings. The presence of XXLG suggests that it is a poor substrate for xyloglucan β-galactosidase. In addition, the polymeric xyloglucan of Atxyl1 lines was found to be enriched in XXLG subunits, with a concomitant decrease in XXFG and XLFG. This change can be explained by extensive exoglycosidase activity at the nonreducing ends of xyloglucan chains. These enzymes could thus have a larger role than previously thought in the metabolism of xyloglucan. Finally, Atxyl1 lines showed a reduced ability to control the anisotropic growth pattern of different organs, pointing to the importance of xyloglucan in this process. The promoter of AtXYL1 was shown to direct expression to many different organs and cell types undergoing cell wall modifications, including trichomes, vasculature, stomata, and elongating anther filaments. PMID:20801759

Could incommensurability in sulfosalts be more common than thought? The case of meneghinite, CuPb13Sb7S24.

PubMed

Bindi, Luca; Petříček, Václav; Biagioni, Cristian; Plášil, Jakub; Moëlo, Yves

2017-06-01

The structure of meneghinite (CuPb 13 Sb 7 S 24 ), from the Bottino mine in the Apuan Alps (Italy), has been solved and refined as an incommensurate structure in four-dimensional superspace. The structure is orthorhombic, superspace group Pnma(0β0)00s, cell parameters a = 24.0549 (3), b = 4.1291 (6), c = 11.3361 (16) Å, modulation vector q = 0.5433 (4)b*. The structure was refined from 6604 reflections to a final R = 0.0479. The model includes modulation of both atomic positions and displacement parameters, as well as occupational waves. The driving forces stabilizing the modulated structure of meneghinite are linked to the occupation modulation of Cu and some of the Pb atoms. As a consequence of the Cu/[] and Pb/Sb modulations, three- to sevenfold coordinations of the M cations (Pb/Sb) occur in different parts of the structure. The almost bimodal distribution of the occupation of Cu/[] and Pb/Sb at M5 conforms with the coupled substitution Sb 3+ + [] → Pb 2+ + Cu + , thus corroborating the hypothesis deduced previously for the incorporation of copper in the meneghinite structure. The very small departure (∼0.54 versus 0.50) from the commensurate value of the modulation raises the question of whether other sulfosalts considered superstructures have been properly described, and, in this light, if incommensurate modulation in sulfosalts could be much more common than thought.

Predictors of suicidal ideation among active duty military personnel with posttraumatic stress disorder.

PubMed

McLean, Carmen P; Zang, Yinyin; Zandberg, Laurie; Bryan, Craig J; Gay, Natalie; Yarvis, Jeffrey S; Foa, Edna B

2017-01-15

Given the alarming rate of military suicides, it is critical to identify the factors that increase risk of suicidal thoughts and behaviors among active duty military personnel. This study examined a predictive model of suicidal ideation among 366 treatment-seeking active duty military personnel with posttraumatic stress disorder (PTSD) following deployments to or near Iraq or Afghanistan. Structural equation modeling was employed to examine the relative contribution of combat exposure, social support, PTSD severity, depressive symptoms, guilt, and trauma-related cognitions on suicidal ideation. The final structural equation model had a highly satisfactory fit [χ 2 (2) =2.023, p=.364; RMSEA =.006; CFI =1; GFI =.998]. PTSD severity had an indirect effect on suicidal ideation via trauma-related cognitions. Depression had a direct positive effect on suicidal ideation; it also had an indirect effect via trauma-related cognitions and interpersonal support. Among participants who had made a previous suicide attempt, only depression symptom severity was significantly linked to suicidal ideation. Data are cross-sectional, precluding causal interpretations. Findings may only generalize to treatment seeking active duty military personnel with PTSD reporting no more than moderate suicidal ideation. These findings suggest that depression and trauma-related cognitions, particularly negative thoughts about the self, play an important role in suicidal ideation among active duty military personnel with PTSD. Negative cognitions about the self and interpersonal support may be important targets for intervention to decrease suicidal ideation. Copyright © 2016 Elsevier B.V. All rights reserved.

How do thoughts, emotions, and decisions align? A new way to examine theory of mind during middle childhood and beyond.

PubMed

Lagattuta, Kristin Hansen; Elrod, Noel M; Kramer, Hannah J

2016-09-01

The current study examined 4- to 10-year-olds' and adults' (N=280) tendency to connect people's thoughts, emotions, and decisions into valence-matched mental state triads (thought valence=emotion valence=decision valence; e.g., anticipate something bad+feel worried+avoid) and valence-matched mental state dyads (thought-emotion, thought-decision, and emotion-decision). Participants heard vignettes about focal characters who re-encountered individuals who had previously harmed them twice, helped them twice, or both harmed and helped them. Baseline trials involved no past experience. Children and adults predicted the focal characters' thoughts (anticipate something good or bad), emotions (feel happy or worried), and decisions (go near or stay away). Results showed significant increases between 4 and 10years of age in the formation of valence-matched mental state triads and dyads, with thoughts and emotions most often aligned by valence. We also documented age-related improvement in awareness that uncertain situations elicit less valence-consistent mental states than more certain situations, with females expecting weaker coherence among characters' thoughts, emotions, and decisions than males. Controlling for age and sex, individuals with stronger executive function (working memory and inhibitory control) predicted more valence-aligned mental states. These findings add to the emerging literature on development and individual differences in children's reasoning about mental states and emotions during middle childhood and beyond. Copyright © 2016 Elsevier Inc. All rights reserved.

Experiential avoidance mediates the association between thought suppression and mindfulness with problem gambling.

PubMed

Riley, Ben

2014-03-01

Experiential avoidance (EA) has been shown to be an important etiological and maintenance factor in a wide range psychopathology that includes addictive, anxiety, depressive and impulse control disorders. One common form of EA is thought suppression. Problem gambling causes enormous problems for afflicted individuals and has major social costs for their families and the community. Despite increasing interest in the contribution of EA to a broad range of psychological problems, its association with problem gambling has not previously been empirically investigated. The purpose of this cross-sectional study was to investigate the relationship between EA, thought suppression, and mindfulness among a group of 103 treatment seeking problem gamblers. Of particular interest was the extent to which EA accounted for the relationships between problem gambling and the two theoretically opposing constructs: thought suppression and mindfulness. Results showed EA was predictive of problem gambling. Thought suppression was positively associated and mindfulness negatively associated with problem gambling, and these relationships were mediated by EA. Directions for future research are suggested which include the application of treatments for problem gambling that undermine EA, such as acceptance and mindfulness based therapies.

External misattribution of internal thoughts and proneness to auditory hallucinations: the effect of emotional valence in the Deese–Roediger–McDermott paradigm

PubMed Central

Kanemoto, Mari; Asai, Tomohisa; Sugimori, Eriko; Tanno, Yoshihiko

2013-01-01

Previous studies have suggested that a tendency to externalize internal thought is related to auditory hallucinations or even proneness to auditory hallucinations (AHp) in the general population. However, although auditory hallucinations are related to emotional phenomena, few studies have investigated the effect of emotional valence on the aforementioned relationship. In addition, we do not know what component of psychotic phenomena relate to externalizing bias. The current study replicated our previous research, which suggested that individual differences in auditory hallucination-like experiences are strongly correlated with the external misattribution of internal thoughts, conceptualized in terms of false memory, using the Deese–Roediger–McDermott (DRM) paradigm. We found a significant relationship between experimental performance and total scores on the Launay–Slade Hallucination Scale (LSHS). Among the LSHS factors, only vivid mental image, which is said to be a predictor of auditory hallucinations, was significantly related to experimental performance. We then investigated the potential effect of emotional valence using the DRM paradigm. The results indicate that participants with low scores on the LSHS (the low-AHp group in the current study) showed an increased discriminability index (d′) for positive words and a decreased d′ for negative words. However, no effects of emotional valence were found for participants with high LSHS scores (high-AHp group). This study indicated that external misattribution of internal thoughts predicts AHp, and that the high-AHp group showed a smaller emotional valence effect in the DRM paradigm compared with the low-AHp group. We discuss this outcome from the perspective of the dual-process activation-monitoring framework in the DRM paradigm in regard to emotion-driven automatic thought in false memory. PMID:23847517

Taboo thoughts and doubt/checking: a refinement of the factor structure for obsessive-compulsive disorder symptoms.

PubMed

Pinto, Anthony; Eisen, Jane L; Mancebo, Maria C; Greenberg, Benjamin D; Stout, Robert L; Rasmussen, Steven A

2007-06-30

The purpose of this report was to improve upon earlier factor analyses of obsessive-compulsive disorder (OCD) symptom categories by minimizing the heterogeneity in the aggressive obsessions category. An exploratory factor analysis was conducted on data from 293 adults with primary OCD. The resulting five factors (Symmetry/Ordering, Hoarding, Doubt/Checking, Contamination/Cleaning, and Taboo Thoughts) are phenomenologically more homogeneous than prior category-based factors and are consistent with those derived in previous item-level analyses.

Investigating thought disorder in schizophrenia: evidence for pathological activation.

PubMed

Safadi, Ziad; Lichtenstein-Vidne, Limor; Dobrusin, Michael; Henik, Avishai

2013-01-01

Previous research has yielded evidence for enhanced semantic priming in formal thought-disordered schizophrenia patients, a result that fits well with the hypothesis of disinhibited processes of spreading activation in this population. The current study examined whether hyper priming among schizophrenia patients is an outcome of further spreading of activation of a node or a result of farther activation of nodes in the semantic network. We also try to shed light on the fate of this activation. The present study tested this hypothesis by using semantic and identical priming in two different experiments. SOA (stimulus onset asynchrony) was manipulated (240 ms vs. 740 ms) within block. It is assumed that among healthy individuals, performance relies on a balance between activation and inhibition processes, contrary to in schizophrenic individuals. In order to examine this hypothesis, we compared formal thought-disordered schizophrenia patients, non thought-disordered schizophrenia patients, and healthy controls. For thought-disordered schizophrenia patients, we found a large positive semantic effect and identical priming effect (129 ms and 154 ms, respectively) only with short SOA. SOA and type of priming did not modulate priming effects in the control groups. This result supports the claim that there is a lack of inhibitory processes among thought-disordered patients. Hyper priming in the thought-disorder group may be an outcome of hyper activation followed by rapid decay below baseline threshold.

Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria.

PubMed

Dulin, David; Bauer, David L V; Malinen, Anssi M; Bakermans, Jacob J W; Kaller, Martin; Morichaud, Zakia; Petushkov, Ivan; Depken, Martin; Brodolin, Konstantin; Kulbachinskiy, Andrey; Kapanidis, Achillefs N

2018-04-16

Transcription in bacteria is controlled by multiple molecular mechanisms that precisely regulate gene expression. It has been recently shown that initial RNA synthesis by the bacterial RNA polymerase (RNAP) is interrupted by pauses; however, the pausing determinants and the relationship of pausing with productive and abortive RNA synthesis remain poorly understood. Using single-molecule FRET and biochemical analysis, here we show that the pause encountered by RNAP after the synthesis of a 6-nt RNA (ITC6) renders the promoter escape strongly dependent on the NTP concentration. Mechanistically, the paused ITC6 acts as a checkpoint that directs RNAP to one of three competing pathways: productive transcription, abortive RNA release, or a new unscrunching/scrunching pathway. The cyclic unscrunching/scrunching of the promoter generates a long-lived, RNA-bound paused state; the abortive RNA release and DNA unscrunching are thus not as tightly linked as previously thought. Finally, our new model couples the pausing with the abortive and productive outcomes of initial transcription.

Intrinsic non-commutativity of closed string theory

DOE PAGES

Freidel, Laurent; Leigh, Robert G.; Minic, Djordje

2017-09-14

We show that the proper interpretation of the cocycle operators appearing in the physical vertex operators of compactified strings is that the closed string target is noncommutative. We track down the appearance of this non-commutativity to the Polyakov action of the at closed string in the presence of translational monodromies (i.e., windings). Here, in view of the unexpected nature of this result, we present detailed calculations from a variety of points of view, including a careful understanding of the consequences of mutual locality in the vertex operator algebra, as well as a detailed analysis of the symplectic structure of themore » Polyakov string. Finally, we also underscore why this non-commutativity was not emphasized previously in the existing literature. This non-commutativity can be thought of as a central extension of the zero-mode operator algebra, an effect set by the string length scale $-$ it is present even in trivial backgrounds. Clearly, this result indicates that the α'→0 limit is more subtle than usually assumed.« less

Regulation of alternative mRNA splicing: old players and new perspectives.

PubMed

Dvinge, Heidi

2018-06-01

Nearly all human multi-exon genes are subject to alternative splicing in one or more cell types. The splicing machinery, therefore, has to select between multiple splice sites in a context-dependent manner, relying on sequence features in cis and trans-acting splicing regulators that either promote or repress splice site recognition and spliceosome assembly. However, the functional coupling between multiple gene regulatory layers signifies that splicing can also be modulated by transcriptional or epigenetic characteristics. Other, less obvious, aspects of alternative splicing have come to light in recent years, often involving core components of the spliceosome previously thought to perform a basal rather than a regulatory role in splicing. Together this paints a highly dynamic picture of splicing regulation, where the final splice site choice is governed by the entire transcriptional environment of a gene and its cellular context. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Impulsive Choice in Mice Lacking Paternal Expression of Grb10 Suggests Intragenomic Conflict in Behavior

PubMed Central

Dent, Claire L.; Humby, Trevor; Lewis, Katie; Ward, Andrew; Fischer-Colbrie, Reiner; Wilkinson, Lawrence S.; Wilkins, Jon F.; Isles, Anthony R.

2018-01-01

Imprinted genes are expressed from one parental allele only as a consequence of epigenetic events that take place in the mammalian germ line and are thought to have evolved through intragenomic conflict between parental alleles. We demonstrate, for the first time, oppositional effects of imprinted genes on brain and behavior. Specifically, we show that mice lacking paternal Grb10 make fewer impulsive choices, with no dissociable effects on a separate measure of impulsive action. Taken together with previous work showing that mice lacking maternal Nesp55 make more impulsive choices, this suggests that impulsive choice behavior is a substrate for the action of genomic imprinting. Moreover, the contrasting effect of these two genes suggests that impulsive choices are subject to intragenomic conflict and that maternal and paternal interests pull this behavior in opposite directions. Finally, these data may also indicate that an imbalance in expression of imprinted genes contributes to pathological conditions such as gambling and drug addiction, where impulsive behavior becomes maladaptive. PMID:29563147

Work, love, and death-thought accessibility: A terror management investigation.

PubMed

McCabe, Simon; Daly, Michael

2018-05-07

Terror management theory suggests that following culturally derived scripts for valued behaviour protects people from death concerns, and conversely, not meeting standards for cultural value can weaken this protection, heightening mortality concerns. Using this conceptual framework, we examine (1) how considerations of loss of employment, a source of cultural value for many, relates to the accessibility of death-related cognition, and (2) the moderating role of job market health, and (3) involvement in close relationships. Study 1 found that writing about being unemployed (vs. a control topic) led to greater mortality-related cognition. Study 2 found that considering unemployment heightened death cognition, but only when participants were led to perceive the job market as unhealthy. Finally, Study 3 found that considering unemployment led to greater death cognition, but not for those involved in a close relationship. Findings offer insight into a previously overlooked consequence of unemployment, and factors that may serve a protective function. © 2018 The British Psychological Society.

Knockdown of a laccase in Populus deltoides confers altered cell wall chemistry and increased sugar release

DOE PAGES

Bryan, Anthony C.; Jawdy, Sara; Gunter, Lee; ...

2016-04-15

Plant laccases are thought to function in the oxidation of monolignols which leads to higher order lignin formation. Only a hand-full of laccases in plants have been functionally evaluated and as such little is known about the breadth of their impact on cell wall chemistry or structure. Here we describe a previously uncharacterized laccase from Populus, encoded by locus Potri.008G06400, whose reduced expression resulted in transgenic Populus trees with changes in syringyl/guaiacyl (S/G) ratios as well as altered sugar release phenotypes. These phenotypes are consistent with plant biomass exhibiting reduced recalcitrance. Interestingly, the transgene effect on recalcitrance is dependent onmore » a mild pretreatment prior to chemical extraction of sugars. Metabolite profiling suggests the transgene modulates phenolics that are associated with the cell wall structure. Finally, we propose a model in which this particular laccase has a range of functions related to oxidation of phenolics that interact with lignin in the cell wall.« less

Knockdown of a laccase in Populus deltoides confers altered cell wall chemistry and increased sugar release

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bryan, Anthony C.; Jawdy, Sara; Gunter, Lee

Plant laccases are thought to function in the oxidation of monolignols which leads to higher order lignin formation. Only a hand-full of laccases in plants have been functionally evaluated and as such little is known about the breadth of their impact on cell wall chemistry or structure. Here we describe a previously uncharacterized laccase from Populus, encoded by locus Potri.008G06400, whose reduced expression resulted in transgenic Populus trees with changes in syringyl/guaiacyl (S/G) ratios as well as altered sugar release phenotypes. These phenotypes are consistent with plant biomass exhibiting reduced recalcitrance. Interestingly, the transgene effect on recalcitrance is dependent onmore » a mild pretreatment prior to chemical extraction of sugars. Metabolite profiling suggests the transgene modulates phenolics that are associated with the cell wall structure. Finally, we propose a model in which this particular laccase has a range of functions related to oxidation of phenolics that interact with lignin in the cell wall.« less

Intrinsic non-commutativity of closed string theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Freidel, Laurent; Leigh, Robert G.; Minic, Djordje

We show that the proper interpretation of the cocycle operators appearing in the physical vertex operators of compactified strings is that the closed string target is noncommutative. We track down the appearance of this non-commutativity to the Polyakov action of the at closed string in the presence of translational monodromies (i.e., windings). Here, in view of the unexpected nature of this result, we present detailed calculations from a variety of points of view, including a careful understanding of the consequences of mutual locality in the vertex operator algebra, as well as a detailed analysis of the symplectic structure of themore » Polyakov string. Finally, we also underscore why this non-commutativity was not emphasized previously in the existing literature. This non-commutativity can be thought of as a central extension of the zero-mode operator algebra, an effect set by the string length scale $-$ it is present even in trivial backgrounds. Clearly, this result indicates that the α'→0 limit is more subtle than usually assumed.« less

Thought beyond language: neural dissociation of algebra and natural language.

PubMed

Monti, Martin M; Parsons, Lawrence M; Osherson, Daniel N

2012-08-01

A central question in cognitive science is whether natural language provides combinatorial operations that are essential to diverse domains of thought. In the study reported here, we addressed this issue by examining the role of linguistic mechanisms in forging the hierarchical structures of algebra. In a 3-T functional MRI experiment, we showed that processing of the syntax-like operations of algebra does not rely on the neural mechanisms of natural language. Our findings indicate that processing the syntax of language elicits the known substrate of linguistic competence, whereas algebraic operations recruit bilateral parietal brain regions previously implicated in the representation of magnitude. This double dissociation argues against the view that language provides the structure of thought across all cognitive domains.

Teaching the EPR Paradox at High School?

ERIC Educational Resources Information Center

Pospiech, Gesche

1999-01-01

Argues the importance of students at university and in the final years of high school gaining an appreciation of the principles of quantum mechanics. Presents the EPR gedanken experiment (thought experiment) as a method of teaching the principles of quantum mechanics. (Author/CCM)

Some Thoughts on Counseling Parents of the Mentally Retarded. Final Report.

ERIC Educational Resources Information Center

Phelps, William R.

Discussed are techniques in counseling parents of retarded children. Suggested are ways to structure the interview as well as methods to help the parents deal with such problems as overprotection and initial reactions to the diagnosis of retardation. (CL)

Diary of a parliamentary intern.

PubMed

Ridge, Anthony

2016-06-25

Anthony Ridge, parliamentary intern to Lord Trees, witnesses the State Opening of Parliament for the first time and realises it carries a lot more significance than he had previously thought. British Veterinary Association.

Identifying the influence of gender on motivation and engagement levels in student physiotherapists.

PubMed

Edgar, Susan

2015-04-01

There is an increasing focus in higher education on the role of learner characteristics and their influence on academic performance. Educators are interested in how students engage with learning activities as they progress through the curriculum. A previous study highlighted gender effects in academic performance in student physiotherapists, despite comparable entry scores. The aim of this study was to determine variation in student motivation and engagement, across the four year levels of the physiotherapy program at The University of Notre Dame Australia while considering gender and age. A cross-sectional design was adopted surveying 233 students utilising the Motivation and Engagement Scale - University/College (MES-UC), to review motivational thoughts and behaviours influencing learning. RESULTS identified gender effects with males having on average significantly lower scores for planning, task management and persistence; and higher scores for disengagement from their studies. Females displayed higher average scores for anxiety particularly in their first year and final clinical year. RESULTS were consistent with gender effects noted in academic performance throughout the program for previous student cohorts. The application of the MES-UC early in course would highlight to educators the areas where intervention can be targeted. Early individualized intervention is recommended to address learner characteristics influencing performance.

Inelastic neutron scattering cross sections for Ge 76 relevant to background in neutrinoless double- β decay experiments

DOE PAGES

Crider, B. P.; Peters, E. E.; Allmond, J. M.; ...

2015-09-11

The experimental signature in searches for the neutrinoless double- decay of 76Ge is a peak near 2039 keV in the spectrum. Given the low probability of the process, it is important that the background in this region be well understood. Moreover, inelastic scattering reactions with neutrons from muon-induced interactions and ( ,n) reactions in the surrounding materials or in the detector can provide contributions to the background. We also measured the production cross sections for rays from the 76Ge(n,n ) reaction in the 2039-keV region at incident neutron energies up to 4.9 MeV. In addition to determining that the crossmore » sections of a previously known 2040.7-keV ray from the 3952-keV level in 76 Ge are rather small, we find that a larger contribution arises from a 2037.5-keV ray which is attributed to a newly identified level at 3147 keV in 76Ge. Finally, a third contribution is also possible from another new level at 3577 keV. These results indicate that the 2039-keV region in 76Ge neutrinoless double- decay searches is more complex than was previously thought.« less

Mice deficient in carbonic anhydrase type 8 exhibit motor dysfunctions and abnormal calcium dynamics in the somatic region of cerebellar granule cells.

PubMed

Lamont, Matthew G; Weber, John T

2015-06-01

The waddles (wdl) mouse is characterized by a namesake "side-to-side" waddling gait due to a homozygous mutation of the Car8 gene. This mutation results in non-functional copies of the protein carbonic anhydrase type 8. Rota-rod testing was conducted to characterize the wdl mutations' effect on motor output. Results indicated that younger homozygotes outperformed their older cohorts, an effect not seen in previous studies. Heterozygotes, which were thought to be free of motor impairment, displayed motor learning deficiencies when compared with wild type performance. Acute cerebellar slices were then utilized for fluorescent calcium imaging experiments, which revealed significant alterations in cerebellar granule cell somatic calcium signaling when exposed to glutamate. The contribution of GABAergic signaling to these alterations was also verified using bath application of bicuculline. Changes in somatic calcium signals were found to be applicable to an in vivo scenario by comparing group responses to electrical stimulation of afferent mossy fiber projections. Finally, intracellular calcium store function was also found to be altered by the wdl mutation when slices were treated with thapsigargin. These findings, taken together with previous work on the wdl mouse, indicate a widespread disruption in cerebellar circuitry hampering proper neuronal communication. Copyright © 2015 Elsevier B.V. All rights reserved.

Genomic Characterization of the Genus Nairovirus (Family Bunyaviridae).

PubMed

Kuhn, Jens H; Wiley, Michael R; Rodriguez, Sergio E; Bào, Yīmíng; Prieto, Karla; Travassos da Rosa, Amelia P A; Guzman, Hilda; Savji, Nazir; Ladner, Jason T; Tesh, Robert B; Wada, Jiro; Jahrling, Peter B; Bente, Dennis A; Palacios, Gustavo

2016-06-10

Nairovirus, one of five bunyaviral genera, includes seven species. Genomic sequence information is limited for members of the Dera Ghazi Khan, Hughes, Qalyub, Sakhalin, and Thiafora nairovirus species. We used next-generation sequencing and historical virus-culture samples to determine 14 complete and nine coding-complete nairoviral genome sequences to further characterize these species. Previously unsequenced viruses include Abu Mina, Clo Mor, Great Saltee, Hughes, Raza, Sakhalin, Soldado, and Tillamook viruses. In addition, we present genomic sequence information on additional isolates of previously sequenced Avalon, Dugbe, Sapphire II, and Zirqa viruses. Finally, we identify Tunis virus, previously thought to be a phlebovirus, as an isolate of Abu Hammad virus. Phylogenetic analyses indicate the need for reassignment of Sapphire II virus to Dera Ghazi Khan nairovirus and reassignment of Hazara, Tofla, and Nairobi sheep disease viruses to novel species. We also propose new species for the Kasokero group (Kasokero, Leopards Hill, Yogue viruses), the Ketarah group (Gossas, Issyk-kul, Keterah/soft tick viruses) and the Burana group (Wēnzhōu tick virus, Huángpí tick virus 1, Tǎchéng tick virus 1). Our analyses emphasize the sister relationship of nairoviruses and arenaviruses, and indicate that several nairo-like viruses (Shāyáng spider virus 1, Xīnzhōu spider virus, Sānxiá water strider virus 1, South Bay virus, Wǔhàn millipede virus 2) require establishment of novel genera in a larger nairovirus-arenavirus supergroup.

Redescription of Cletocamptus albuquerquensis and C. dominicanus (Harpacticoida: Canthocamptidae incertae sedis), and description of two new species from the US Virgin Islands and Bonaire.

PubMed

Gómez, Samuel; Gerber, Ray; Fuentes-Reinés, Juan Manuel

2017-05-30

The history surrounding the identity of Cletocamptus albuquerquensis (Herrick, 1894) and C. dominicanus Kiefer, 1934 is very complex. This complexity has been exacerbated by incomplete, and in some cases erroneous, original descriptions of these two species. Also, new records from other locations did not describe the significant characters needed to clearly delineate them. This led several authors to consider C. dominicanus as a synonym of C. albuquerquensis, among other taxonomical considerations regarding, for example, the status of Marshia brevicaudata Herrick, 1894. Inspection of biological material from Saskatchewan (southern Canada), Wyoming (central US), Trinidad and Tobago, and the British Virgin Islands, identified by other researchers as C. albuquerquensis, as well as of newly collected material from Great Salt Lake (Utah, central US), Puerto Rico, Culebra Island, Vieques Island, St. John Island (US Virgin Islands), San Salvador (Bahamas), and Santa Marta (Colombia), revealed that C. albuquerquensis and C. dominicanus are distinct and identifiable species, distributed in a more restricted area than previously thought. Additionally, we describe a new species, C. tainoi sp. nov., from St. John Island (US Virgin Islands), and we propose another new species, C. chappuisi sp. nov., for two males from Bonaire previously identified as C. albuquerquensis. Finally, we give some observations on tube-pore-like structures, previously overlooked, on the endopod of the male leg three.

Free-floating Failed Star Artist Concept

NASA Image and Video Library

2013-09-05

This artist concept portrays a free-floating brown dwarf, or failed star. A new study using data from NASA Spitzer Space Telescope shows that several of these objects are warmer than previously thought.

SAGE II V7

Atmospheric Science Data Center

2017-09-06

... The series of Stratospheric Aerosol and Gas Experiments (SAGE I, II, and III) are satellite-based solar occultation ... significantly more shortwave radiation than previously thought. Clouds in a Clear Sky Scientists have detected a nearly ...

Affective and cognitive determinants of women's sexual response to erotica.

PubMed

Vilarinho, Sandra; Laja, Pedro; Carvalho, Joana; Quinta-Gomes, Ana Luísa; Oliveira, Cátia; Janssen, Erick; Nobre, Pedro J

2014-11-01

The specific cognitive-affective mechanisms involved in the activation and regulation of the subjective and genital components of sexual arousal are not fully understood yet. The aim of the present study was to investigate the contribution of self-reported thoughts and affect to the prediction of women's subjective and genital responses to erotica. Twenty-eight sexually functional women (mean age = 32, SD = 6.29) were presented with sexually explicit and nonexplicit romantic films. Genital responses, subjective sexual arousal, state affect, and self-reported thoughts were assessed. Vaginal pulse amplitude was measured using a vaginal photoplethysmograph. Subjective sexual arousal, thoughts, and affective responses were assessed through self-report scales. Correlations between subjective and physiological sexual arousal were low (r = -0.05, P > 0.05). Self-reported thoughts and affect were significant predictors of subjective sexual arousal. The strongest single predictor of subjective arousal was sexual arousal thoughts (e.g., "I'm getting excited") (β = 0.63, P < 0.01). None of the cognitive or affective variables predicted women's genital responses. Overall, results support the role of cognitive (self-reported thoughts) and affective dimensions in women's subjective sexual arousal to erotica and, consistent with previous findings, suggest that subjective and physiological sexual arousal may be impacted by different processes. © 2014 International Society for Sexual Medicine.

Emerging air monitoring technologies and thoughts on role of Department of State

EPA Science Inventory

The slides will support topics ranging from federal reference/equivalent level monitoring that is already underway at a number of embassies and consulates worldwide, as well as discuss non-regulatory research methods that could be considered to answer specific questions. Finally...

Evidence of native starch degradation with human small intestinal maltase-glucoamylase (recombinant)

USDA-ARS?s Scientific Manuscript database

Action of human small intestinal brush border carbohydrate digesting enzymes is thought to involve only final hydrolysis reactions of oligosaccharides to monosaccharides. In vitro starch digestibility assays use fungal amyloglucosidase to provide this function. In this study, recombinant N-terminal ...

An Array Processing Theory of Memory, Thought, and Behavior Patterning: A Radically Reconstructive View.

ERIC Educational Resources Information Center

Allison, Dennis J.

A theory of memory is introduced, which seeks to respond to the shortcomings of existing theories based on metaphors. Memory is presented as a mechanism, a comparison process in which information held in some form of immediate storage (whether based on perception or previous cognition or both) is compared to previously stored long-term storage.…

Everyday magical powers: the role of apparent mental causation in the overestimation of personal influence.

PubMed

Pronin, Emily; Wegner, Daniel M; McCarthy, Kimberly; Rodriguez, Sylvia

2006-08-01

These studies examined whether having thoughts related to an event before it occurs leads people to infer that they caused the event--even when such causation might otherwise seem magical. In Study 1, people perceived that they had harmed another person via a voodoo hex. These perceptions were more likely among those who had first been induced to harbor evil thoughts about their victim. In Study 2, spectators of a peer's basketball-shooting performance were more likely to perceive that they had influenced his success if they had first generated positive visualizations consistent with that success. Observers privy to those spectators' visualizations made similar attributions about the spectators' influence. Finally, additional studies suggested that these results occur even when the thought-about outcome is viewed as unwanted by the thinker and even in field settings where the relevant outcome is occurring as part of a live athletic competition.

SAGE II V6.20

Atmospheric Science Data Center

2017-09-06

... The series of Stratospheric Aerosol and Gas Experiments (SAGE I, II, and III) are satellite-based solar occultation ... significantly more shortwave radiation than previously thought. Clouds in a Clear Sky Scientists have detected a nearly ...

Astrophysics: The supernova has two faces

NASA Astrophysics Data System (ADS)

Kasen, Daniel

2010-07-01

The variety of stellar deaths is less than we thought. A compilation of new and archival data shows that two previously distinct subtypes of supernova are actually two sides of the same lopsided coin.

Urbanism, Migration, and Tolerance: A Reassessment.

ERIC Educational Resources Information Center

Wilson, Thomas C.

1991-01-01

Urbanism's impact on the personality may be stronger than previously thought. Finds that urban residence has a strong positive effect on tolerance. Migration also promotes tolerance, regardless of the size of the destination community. (DM)

Life in extreme environments.

PubMed

Rothschild, L J; Mancinelli, R L

2001-02-22

Each recent report of liquid water existing elsewhere in the Solar System has reverberated through the international press and excited the imagination of humankind. Why? Because in the past few decades we have come to realize that where there is liquid water on Earth, virtually no matter what the physical conditions, there is life. What we previously thought of as insurmountable physical and chemical barriers to life, we now see as yet another niche harbouring 'extremophiles'. This realization, coupled with new data on the survival of microbes in the space environment and modelling of the potential for transfer of life between celestial bodies, suggests that life could be more common than previously thought. Here we examine critically what it means to be an extremophile, and the implications of this for evolution, biotechnology and especially the search for life in the Universe.

Life in Extreme Environments

NASA Technical Reports Server (NTRS)

Rothschild, Lynn; Bram, James A. (Technical Monitor)

2002-01-01

Each recent report of liquid water existing elsewhere in the solar system has reverberated through the international press and excited the imagination of humankind. Why? Because in the last few decades we have come to realize that where there is liquid water on Earth, virtually no matter what the physical conditions, there is life. What we previously thought of as insurmountable physical and chemical barriers to life, we now see as yet another niche harboring 'extremophiles'. This realization, coupled with new data on the survival of microbes in the space environment and modeling of the potential for transfer of life between celestial bodies, suggests that life could be more common than previously thought. Here we critically examine what it means to be an extremophile, the implications of this for evolution, biotechnology, and especially the search for life in the cosmos.

Development of the selection and manipulation of self-generated thoughts in adolescence.

PubMed

Dumontheil, Iroise; Hassan, Bano; Gilbert, Sam J; Blakemore, Sarah-Jayne

2010-06-02

The ability to select and manipulate self-generated (stimulus-independent, SI), as opposed to stimulus-oriented (SO), information, in a controlled and flexible way has previously only been studied in adults. This ability is thought to rely in part on the rostrolateral prefrontal cortex (RLPFC), which continues to mature anatomically during adolescence. We investigated (1) the development of this ability behaviorally, (2) the associated functional brain development, and (3) the link between functional and structural maturation. Participants classified according to their shape letters either presented visually (SO phases) or that they generated in their head by continuing the alphabet sequence (SI phases). SI phases were performed in the presence or absence of distracting letters. A total of 179 participants (7-27 years old) took part in a behavioral study. Resistance to visual distractors exhibited small improvements with age. SI thoughts manipulation and switching between SI and SO thoughts showed steeper performance improvements extending into late adolescence. Thirty-seven participants (11-30 years old) took part in a functional MRI (fMRI) study. SI thought manipulation and switching between SO and SI thought were each associated with brain regions consistently recruited across age. A single frontal brain region in each contrast exhibited decreased activity with age: left inferior frontal gyrus/anterior insula for SI thought manipulation, and right superior RLPFC for switching between SO and SI thoughts. By integrating structural and functional data, we demonstrated that the observed functional changes with age were not purely consequences of structural maturation and thus may reflect the maturation of neurocognitive strategies.

Activating analytic thinking enhances the value given to individualizing moral foundations.

PubMed

Yilmaz, Onurcan; Saribay, S Adil

2017-08-01

Two central debates within Moral Foundations Theory concern (1) which moral foundations are core and (2) how conflict between ideological camps stemming from valuing different moral foundations can be resolved. Previous studies have attempted to answer the first question by imposing cognitive load on participants to direct them toward intuitive and automatic thought. However, this method has limitations and has produced mixed findings. In the present research, in two experiments, instead of directing participants toward intuitive thought, we tested the effects of activating high-effort, analytic thought on participants' moral foundations. In both experiments, analytic thought activation caused participants to value individualizing foundations greater than the control condition. This effect was not qualified by participants' political orientation. No effect was observed on binding foundations. The results are consistent with the idea that upholding individualizing foundations requires mental effort and may provide the basis for reconciliation between different ideological camps. Copyright © 2017 Elsevier B.V. All rights reserved.

The effect of relations in paired-associate learning.

PubMed

Wilton, Richard N

2006-02-01

Previous studies have shown that the cued recall of paired associates is greater when one member of a pair has been apprehended as lying on the other member, as compared with the two having been apprehended as independent objects. The effect occurs when the objects have been perceived, imagined, or described in the relevant relationship. The additional thoughts hypothesis postulates that participants have more spontaneous "additional thoughts" when apprehending a pair in the relational condition. These may provide additional retrieval routes, thereby explaining the effect. In four experiments, the hypothesis was tested under conditions in which a clear unambiguous definition could be specified for an additional thought. The results showed that the greater recall in an "on" condition, as compared with an independent condition, occurs at least in part because more additional thoughts occur in the "on" condition. There was no evidence for any other contribution to the effect. It is argued that the findings question whether relations between objects play a fundamental role in the structure of memory.

The presence of magical thinking in obsessive compulsive disorder.

PubMed

Einstein, Danielle A; Menzies, Ross G

2004-05-01

Two research groups have raised the possibility that magical ideation may be a fundamental feature of obsessive-compulsive disorder. It has been proposed to underlie thought action fusion and superstitious beliefs. In this study, the Magical Ideation scale, the Lucky Behaviours and Lucky Beliefs scales, the Thought Action Fusion-Revised scale, the Padua Inventory, and the Obsessive Compulsive Inventory-Short Version were completed by 60 obsessive compulsive patients at a hospital clinic. Of all the measures, the Magical Ideation (MI) scale was found to be the most strongly related to obsessive compulsive symptoms. Large and significant relationships between MI scores and the measures of OCD were obtained even when alternative constructs (Lucky Behaviours, Lucky Beliefs, Thought Action Fusion-Revised scales) were held constant. No other variable remained significantly related to the Obsessive Compulsive Inventory-Short Version when magical ideation scores were held constant. The findings suggest that a general magical thinking tendency may underpin previous observed links between superstitiousness, thought action fusion and OCD severity.

Beyond data collection in digital mapping: interpretation, sketching and thought process elements in geological map making

NASA Astrophysics Data System (ADS)

Watkins, Hannah; Bond, Clare; Butler, Rob

2016-04-01

Geological mapping techniques have advanced significantly in recent years from paper fieldslips to Toughbook, smartphone and tablet mapping; but how do the methods used to create a geological map affect the thought processes that result in the final map interpretation? Geological maps have many key roles in the field of geosciences including understanding geological processes and geometries in 3D, interpreting geological histories and understanding stratigraphic relationships in 2D and 3D. Here we consider the impact of the methods used to create a map on the thought processes that result in the final geological map interpretation. As mapping technology has advanced in recent years, the way in which we produce geological maps has also changed. Traditional geological mapping is undertaken using paper fieldslips, pencils and compass clinometers. The map interpretation evolves through time as data is collected. This interpretive process that results in the final geological map is often supported by recording in a field notebook, observations, ideas and alternative geological models explored with the use of sketches and evolutionary diagrams. In combination the field map and notebook can be used to challenge the map interpretation and consider its uncertainties. These uncertainties and the balance of data to interpretation are often lost in the creation of published 'fair' copy geological maps. The advent of Toughbooks, smartphones and tablets in the production of geological maps has changed the process of map creation. Digital data collection, particularly through the use of inbuilt gyrometers in phones and tablets, has changed smartphones into geological mapping tools that can be used to collect lots of geological data quickly. With GPS functionality this data is also geospatially located, assuming good GPS connectivity, and can be linked to georeferenced infield photography. In contrast line drawing, for example for lithological boundary interpretation and sketching, is yet to find the digital flow that is achieved with pencil on notebook page or map. Free-form integrated sketching and notebook functionality in geological mapping software packages is in its nascence. Hence, the result is a tendency for digital geological mapping to focus on the ease of data collection rather than on the thoughts and careful observations that come from notebook sketching and interpreting boundaries on a map in the field. The final digital geological map can be assessed for when and where data was recorded, but the thought processes of the mapper are less easily assessed, and the use of observations and sketching to generate ideas and interpretations maybe inhibited by reliance on digital mapping methods. All mapping methods used have their own distinct advantages and disadvantages and with more recent technologies both hardware and software issues have arisen. We present field examples of using conventional fieldslip mapping, and compare these with more advanced technologies to highlight some of the main advantages and disadvantages of each method and discuss where geological mapping may be going in the future.

Lingering representations of stimuli influence recall organization

PubMed Central

Chan, Stephanie C.Y.; Applegate, Marissa C.; Morton, Neal W; Polyn, Sean M.; Norman, Kenneth A.

2017-01-01

Several prominent theories posit that information about recent experiences lingers in the brain and organizes memories for current experiences, by forming a temporal context that is linked to those memories at encoding. According to these theories, if the thoughts preceding an experience X resemble the thoughts preceding an experience Y, then X and Y should show an elevated probability of being recalled together. We tested this prediction by using multi-voxel pattern analysis (MVPA) of fMRI data to measure neural evidence for lingering processing of preceding stimuli. As predicted, memories encoded with similar lingering thoughts about the category of preceding stimuli were more likely to be recalled together. Our results demonstrate that the “fading embers” of previous stimuli help to organize recall, confirming a key prediction of computational models of episodic memory. PMID:28132858

Maladaptive repetitive thought as a transdiagnostic phenomenon and treatment target: An integrative review.

PubMed

Kaplan, Deanna M; Palitsky, Roman; Carey, Angela L; Crane, Tracy E; Havens, Cody M; Medrano, Michael R; Reznik, Samantha J; Sbarra, David A; O'Connor, Mary-Frances

2018-07-01

Maladaptive repetitive thought (RT), the frequent and repetitive revisiting of thoughts or internal experiences, is associated with a range of psychopathological processes and disorders. We present a synthesis of prior research on maladaptive RT and develop a framework for elucidating and distinguishing between five forms of maladaptive RT. In addition to the previously studied maladaptive RT (worry, rumination, and obsession), this framework is used to identify two additional forms of maladaptive RT (yearning and interoceptive RT). We then present a review of extant psychotherapy intervention research targeting maladaptive RT, focusing both on specific empirically based treatment strategies, and also constructs within treatments that impact maladaptive RT. The paper concludes with recommendations for future basic and intervention research on maladaptive RT and related psychopathologies. © 2018 Wiley Periodicals, Inc.

"I Finally Get It!": Developing Mathematical Understanding during Teacher Education

ERIC Educational Resources Information Center

Holm, Jennifer; Kajander, Ann

2012-01-01

A deep conceptual understanding of elementary mathematics as appropriate for teaching is increasingly thought to be an important aspect of elementary teacher capacity. This study explores preservice teachers' initial mathematical understandings and how these understandings developed during a mathematics methods course for upper elementary…

Einstein's creative thinking and the general theory of relativity: a documented report.

PubMed

Rothenberg, A

1979-01-01

A document written by Albert Einstein has recently come to light in which the eminent scientist described the actual sequence of his thoughts leading to the development of the general theory of relativity. The key creative thought was an instance of a type of creative cognition the author has previously designated "Janusian thinking," Janusian thinking consists of actively conceiving two or more opposite or antithetical concepts, ideas, or images simultaneously. This form of high-level secondary process cognition has been found to operate widely in art, science, and other fields.

Depression and suicidal ideation among Canadians aged 15 to 24.

PubMed

Findlay, Leanne

2017-01-18

Among Canadians aged 15 to 24, the rate of depression is higher than at any other age, and suicide is the second leading cause of death. The current study provides detailed information about depression and suicidal ideation among young Canadians, including their use of mental health support. Data from the 2012 Canadian Community Health Survey-Mental Health (CCHS-MH) were used to describe rates and experiences of depression and suicidal ideation among Canadians aged 15 to 24, including psychosocial characteristics of those who had depression or reported suicidal thoughts. Characteristics associated with seeking professional support were also examined. About 11% of Canadians aged 15 to 24 had experienced depression in their lifetime; 7%, in the past year. Approximately 14% reported having had suicidal thoughts in their lifetime; 6%, in the past year. Lifetime depression and suicidal thoughts were moderately correlated (r = .34, p ⟨ .001). Individuals with lifetime depression had more than four times the odds of seeking professional support in the previous year, compared with those who did not have lifetime depression; those with lifetime suicidal thoughts had more than three times the odds of seeking professional support, compared with those who did not have lifetime suicidal thoughts. Psychosocial factors such as negative social interactions and lower perceived ability to deal with stress were associated with depression and suicidal thoughts, although these associations differed for males and females. The findings suggest that many young Canadians have depression and/or suicidal thoughts. Their odds of seeking professional support are significantly high.

An expanded role for river networks

Treesearch

Jonathan P. Benstead; David S. Leigh

2012-01-01

Estimates of stream and river area have relied on observations at coarse resolution. Consideration of the smallest and most dynamic streams could reveal a greater role for river networks in global biogeochemical cycling than previously thought.

Self-Reported Stickiness of Mind-Wandering Affects Task Performance

PubMed Central

van Vugt, Marieke K.; Broers, Nico

2016-01-01

When asked to perform a certain task, we typically spend a decent amount of time thinking thoughts unrelated to that task–a phenomenon referred to as “mind-wandering.” It is thought that this mind-wandering is driven at least in part by our unfinished goals and concerns. Previous studies have shown that just after presenting a participant with their own concerns, their reports of task-unrelated thinking increased somewhat. However, effects of these concerns on task performance were somewhat inconsistent. In this study we take the opposite approach, and examine whether task performance depends on the self-reported thought content. Specifically, a particularly intriguing aspect of mind-wandering that has hitherto received little attention is the difficulty of disengaging from it, in other words, the “stickiness” of the thoughts. While presenting participants with their own concerns was not associated with clear effects on task performance, we showed that the reports of off-task thinking and variability of response times increased with the amount of self-reported stickiness of thoughts. This suggests that the stickiness of mind-wandering is a relevant variable, and participants are able to meaningfully report on it. PMID:27242636

Chameleon Chasing II: A Replication.

ERIC Educational Resources Information Center

Newsom, Doug A.; And Others

1993-01-01

Replicates a 1972 survey of students, educators, and Public Relations Society of America members regarding who the public relations counselor really serves. Finds that, in 1992, most respondents thought primary responsibility was to the client, then to the client's relevant publics, then to self, then to society, and finally to media. Compares…

The Draining Cylinder

ERIC Educational Resources Information Center

James Graham-Eagle

2009-01-01

This article explores the time it takes for a liquid to drain from a cylindrical container through a hole in the bottom. Using dimensional analysis and some thought experiments this time is determined and Torricelli's law derived as a consequence. Finally, the effect of pouring liquid into the container as it drains is considered.

Emotional Schemas and Resistance to Change in Anxiety Disorders

ERIC Educational Resources Information Center

Leahy, Robert L.

2007-01-01

Cognitive-behavioral treatment for all anxiety disorders involves exposure to feared situations and feared emotions. Dropout from therapy is a continued problem for final treatment effectiveness. A meta-emotional model of fear of negative emotions (and anxious sensations and thoughts) is advanced that can be used as a transdiagnostic treatment…

Towards a wave theory of charged beam transport: A collection of thoughts

NASA Technical Reports Server (NTRS)

Dattoli, G.; Mari, C.; Torre, A.

1992-01-01

We formulate in a rigorous way a wave theory of charged beam linear transport. The Wigner distribution function is introduced and provides the link with classical mechanics. Finally, the von Neumann equation is shown to coincide with the Liouville equation for the nonlinear transport.

Education Essays: Thoughts on Teaching.

ERIC Educational Resources Information Center

Inoue, Yukiko

This paper consists of seven short essays concerning teaching in general and college teaching in particular. Then first five essays were published in "APA Perspective," a newsletter of the National Association for Asian and Pacific Islander Education, and were revised for this paper. The final two essays are new. The titles are: (1)…

75 FR 14059 - Federal Acquisition Regulation; FAR Case 2008-027, Federal Awardee Performance and Integrity...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-23

.... Without the language, contracting officers may think they are required to utilize outdated information... Government and its institution. In particular, one respondent thought that the estimates would have to be...), and National Aeronautics and Space Administration (NASA). ACTION: Final rule. SUMMARY: The Civilian...

The Meaning of "Success" for First Nations Schools

ERIC Educational Resources Information Center

Churcher, Kassandra

2010-01-01

When the First Nations Student Success Program (FNSSP) was first introduced in September 2009, the author's initial thought was: "No Child Left Behind (NCLB) has finally arrived in Canada." It seemed prophetic that the 2010 spring issue of "Education Canada" contained both a piece by Joel Westheimer warning against the pitfalls…

Outgassed water on Mars - Constraints from melt inclusions in SNC meteorites

NASA Technical Reports Server (NTRS)

Mcsween, Harry Y., Jr.; Harvey, Ralph P.

1993-01-01

The SNC (shergottite-nakhlite-chassignite) meteorites, thought to be igneous rocks from Mars, contain melt inclusions trapped at depth in early-formed crystals. Determination of the pre-eruptive water contents of SNC parental magmas from calculations of the solidification histories of these amphibole-bearing inclusions indicates that Martian magmas commonly contained 1.4 percent water by weight. When combined with an estimate of the volume of igneous materials on Mars, this information suggests that the total amount of water outgassed since 3.9 billion years ago corresponds to global depths on the order of 200 meters. This value is significantly higher than previous geochemical estimates but lower than estimates based on erosion by floods. These results imply a wetter Mars interior than has been previously thought and support suggestions of significant outgassing before formation of a stable crust or heterogeneous accretion of a veneer of cometary matter.

Isolated prospective confabulation in Wernicke-Korsakoff syndrome: a case for reality filtering.

PubMed

Schnider, Armin; Nahum, Louis; Pignat, Jean-Michel; Leemann, Béatrice; Lövblad, Karl-Olof; Wissmeyer, Michael; Ptak, Radek

2013-01-01

A 57-year-old man suffered severe amnesia and disorientation, accompanied by content-specific confabulation, due to an alcoholic Wernicke-Korsakoff syndrome. For months, he was deeply concerned about a single obligation that he thought he had to respond to, but which he had already assumed 20 years previously. This monothematic, prospective confabulation was associated with failures of reality filtering as previously documented in behaviorally spontaneous confabulation and disorientation: the patient failed to suppress the interference of currently irrelevant memories and to abandon anticipations that were no longer valid (impaired extinction capacity). Magnetic resonance imaging showed damage to the mamillary bodies and the dorsomedial thalamic nucleus. Positron emission tomography (FDG-PET) showed extended orbitofrontal hypometabolism. We suggest that isolated prospective confabulation shares the core feature (acts and thoughts based on currently irrelevant memory), mechanism (failure of reality filtering), and anatomical basis (orbitofrontal dysfunction) with behaviorally spontaneous confabulations.

Thought Suppression in Patients With Bipolar Disorder

PubMed Central

Miklowitz, David J.; Alatiq, Yousra; Geddes, John R.; Goodwin, Guy M.; Williams, J. Mark G.

2010-01-01

Suppression of negative thoughts has been observed under experimental conditions among patients with major depressive disorder (MDD) but has never been examined among patients with bipolar disorder (BD). Patients with BD (n = 36), patients with MDD (n = 20), and healthy controls (n = 20) completed a task that required unscrambling 6-word strings into 5-word sentences, leaving out 1 word. The extra word allowed the sentences to be completed in a negative, neutral, or “hyperpositive” (manic/goal-oriented) way. Participants completed the sentences under conditions of cognitive load (rehearsing a 6-digit number), reward (a bell tone), load and reward, or neither load nor reward. We hypothesized that patients with BD would engage in more active suppression of negative and hyperpositive thoughts than would controls, as revealed by their unscrambling more word strings into negative or hyperpositive sentences. Under conditions of load or reward and in the absence of either load or reward, patients with BD unscrambled more negative sentences than did controls. Under conditions of reward, patients with BD unscrambled more negative sentences than did patients with MDD. Patients with BD also reported more use of negative thought suppression than did controls. These group differences in negative biases were no longer significant when current mood states were controlled. Finally, the groups did not differ in the proportion of hyperpositive sentence completions in any condition. Thought suppression may provide a critical locus for psychological interventions in BD. PMID:20455608

[Study thought of material basis of secondary development of major traditional Chinese medicine varieties on basis of combination of in vivo and in vitro experiments].

PubMed

Cheng, Xu-Dong; Jia, Xiao-Bin; Feng, Liang; Jiang, Jun

2013-12-01

The secondary development of major traditional Chinese medicine varieties is one of important links during the modernization, scientification and standardization of traditional Chinese medicines. How to accurately and effectively identify the pharmacodynamic material basis of original formulae becomes the primary problem in the secondary development, as well as the bottleneck in the modernization development of traditional Chinese medicines. On the basis of the existing experimental methods, and according to the study thought that the multi-component and complex effects of traditional Chinese medicine components need to combine multi-disciplinary methods and technologies, we propose the study thought of the material basis of secondary development of major traditional Chinese medicine varieties based on the combination of in vivo and in vitro experiments. It is believed that studies on material basis needs three links, namely identification, screening and verification, and in vivo and in vitro study method corresponding to each link is mutually complemented and verified. Finally, the accurate and reliable material basis is selected. This thought provides reference for the secondary development of major traditional Chinese medicine varieties and studies on compound material basis.

A theoretical and empirical review of the death-thought accessibility concept in terror management research.

PubMed

Hayes, Joseph; Schimel, Jeff; Arndt, Jamie; Faucher, Erik H

2010-09-01

Terror management theory (TMT) highlights the motivational impact of thoughts of death in various aspects of everyday life. Since its inception in 1986, research on TMT has undergone a slight but significant shift from an almost exclusive focus on the manipulation of thoughts of death to a marked increase in studies that measure the accessibility of death-related cognition. Indeed, the number of death-thought accessibility (DTA) studies in the published literature has grown substantially in recent years. In light of this increasing reliance on the DTA concept, the present article is meant to provide a comprehensive theoretical and empirical review of the literature employing this concept. After discussing the roots of DTA, the authors outline the theoretical refinements to TMT that have accompanied significant research findings associated with the DTA concept. Four distinct categories (mortality salience, death association, anxiety-buffer threat, and dispositional) are derived to organize the reviewed DTA studies, and the theoretical implications of each category are discussed. Finally, a number of lingering empirical and theoretical issues in the DTA literature are discussed with the aim of stimulating and focusing future research on DTA specifically and TMT in general.

Lingering representations of stimuli influence recall organization.

PubMed

Chan, Stephanie C Y; Applegate, Marissa C; Morton, Neal W; Polyn, Sean M; Norman, Kenneth A

2017-03-01

Several prominent theories posit that information about recent experiences lingers in the brain and organizes memories for current experiences, by forming a temporal context that is linked to those memories at encoding. According to these theories, if the thoughts preceding an experience X resemble the thoughts preceding an experience Y, then X and Y should show an elevated probability of being recalled together. We tested this prediction by using multi-voxel pattern analysis (MVPA) of fMRI data to measure neural evidence for lingering processing of preceding stimuli. As predicted, memories encoded with similar lingering thoughts about the category of preceding stimuli were more likely to be recalled together. Our results demonstrate that the "fading embers" of previous stimuli help to organize recall, confirming a key prediction of computational models of episodic memory. Copyright © 2017 Elsevier Ltd. All rights reserved.

The relationship of thought-action fusion to pathologicial worry and generalized anxiety disorder.

PubMed

Hazlett-Stevens, Holly; Zucker, Bonnie G; Craske, Michelle G

2002-10-01

Meta-cognitive beliefs associated with pathological worry and generalized anxiety disorder (GAD) may encompass the likelihood subtype of thought-action fusion (TAF), the belief that one's thoughts can influence outside events. In the current study of 494 undergraduate college students, positive correlations between scores on the Penn State Worry Questionnaire (PSWQ) and the two Likelihood subscales of the TAF Scale were found, and participants endorsing at least some DSM-IV diagnostic criteria for GAD scored significantly higher on both TAF-Likelihood subscales than participants reporting no GAD symptoms. However, these TAF scales did not predict GAD diagnostic status with PSWQ included as a predictor. In contrast to previous research, the TAF-Moral scale did not correlate with worry. Relationships between TAF, pathological worry, and meta-cognition are discussed in relation to GAD.

Revising the Local Bubble Model due to Solar Wind Charge Exchange X-ray Emission

NASA Astrophysics Data System (ADS)

Shelton, Robin L.

The hot Local Bubble surrounding the solar neighborhood has been primarily studied through observations of its soft X-ray emission. The measurements were obtained by attributing all of the observed local soft X-rays to the bubble. However, mounting evidence shows that the heliosphere also produces diffuse X-rays. The source is solar wind ions that have received an electron from another atom. The presence of this alternate explanation for locally produced diffuse X-rays calls into question the existence and character of the Local Bubble. This article addresses these questions. It reviews the literature on solar wind charge exchange (SWCX) X-ray production, finding that SWCX accounts for roughly half of the observed local 1/4 keV X-rays found at low latitudes. This article also makes predictions for the heliospheric O VI column density and intensity, finding them to be smaller than the observational error bars. Evidence for the continued belief that the Local Bubble contains hot gas includes the remaining local 1/4 keV intensity, the observed local O VI column density, and the need to fill the local region with some sort of plasma. If the true Local Bubble is half as bright as previously thought, then its electron density and thermal pressure are 1/sqrt{2} as great as previously thought, and its energy requirements and emission measure are 1/2 as great as previously thought. These adjustments can be accommodated easily, and, in fact, bring the Local Bubble's pressure more in line with that of the adjacent material. Suggestions for future work are made.

Revising the Local Bubble Model due to Solar Wind Charge Exchange X-ray Emission

NASA Astrophysics Data System (ADS)

Shelton, Robin L.

2009-03-01

The hot Local Bubble surrounding the solar neighborhood has been primarily studied through observations of its soft X-ray emission. The measurements were obtained by attributing all of the observed local soft X-rays to the bubble. However, mounting evidence shows that the heliosphere also produces diffuse X-rays. The source is solar wind ions that have received an electron from another atom. The presence of this alternate explanation for locally produced diffuse X-rays calls into question the existence and character of the Local Bubble. This article addresses these questions. It reviews the literature on solar wind charge exchange (SWCX) X-ray production, finding that SWCX accounts for roughly half of the observed local 1/4 keV X-rays found at low latitudes. This article also makes predictions for the heliospheric O VI column density and intensity, finding them to be smaller than the observational error bars. Evidence for the continued belief that the Local Bubble contains hot gas includes the remaining local 1/4 keV intensity, the observed local O VI column density, and the need to fill the local region with some sort of plasma. If the true Local Bubble is half as bright as previously thought, then its electron density and thermal pressure are 1/sqrt{2} as great as previously thought, and its energy requirements and emission measure are 1/2 as great as previously thought. These adjustments can be accommodated easily, and, in fact, bring the Local Bubble’s pressure more in line with that of the adjacent material. Suggestions for future work are made.

Immediate source-monitoring, self-focused attention and the positive symptoms of schizophrenia.

PubMed

Startup, Mike; Startup, Sue; Sedgman, Adele

2008-10-01

Previous research suggests that tendencies to misattribute one's own thoughts to an external source, as assessed by an immediate source-monitoring test, are associated with auditory verbal hallucinations (AVHs). However, recent research suggests that such tendencies are associated instead with symptoms of thought interference. The main aim of the present study was to examine whether such tendencies are differentially associated with different types of thought interference, with AVHs, or with both. It has also been suggested that external misattributions are especially likely to occur with emotionally salient material and if the individual's focus is on the self. These suggestions were also tested. The positive psychotic symptoms of 57 individuals with a diagnosis of schizophrenia were assessed and they then completed the Self-Focus Sentence Completion blank. Immediately after completing each sentence they were asked to indicate to what extent the sentence was their own. The number of sentences that were not rated as completely their own served as their externalization score. Externalization scores correlated significantly with the severity of three symptoms: voices commenting, delusions of being controlled, and thought insertion. In a logistic regression analysis, all three of these symptoms were significantly and independently related to externalization. Externalization was not associated with either a negative or a neutral self-focus. Thus tendencies to misattribute one's own thoughts to an external source are associated with AVHs and some, but not all, symptoms of thought interference. The importance for externalization of self-focused attention and of the emotional salience of the elicited thoughts was not supported.

Molecular genetic analysis of activation-tagged transcription factors thought to be involved in photomorphogenesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Neff, Michael M.

This is a final report for Department of Energy Grant No. DE-FG02-08ER15927 entitled “Molecular Genetic Analysis of Activation-Tagged Transcription Factors Thought to be Involved in Photomorphogenesis”. Based on our preliminary photobiological and genetic analysis of the sob1-D mutant, we hypothesized that OBP3 is a transcription factor involved in both phytochrome and cryptochrome-mediated signal transduction. In addition, we hypothesized that OBP3 is involved in auxin signaling and root development. Based on our preliminary photobiological and genetic analysis of the sob2-D mutant, we also hypothesized that a related gene, LEP, is involved in hormone signaling and seedling development.

[The bioresorbable coronary stent: a revolution].

PubMed

Koegler, Flora; De Benedetti, Edoardo

2013-04-10

Coronary angioplasty has undergone several technological revolutions: starting with balloon angioplasty, then with bare metal stent and finally with drug eluting stent (DES), this technique is now mature. However, once we thought the problem of instent restenosis solved with DES, new concerns arise with late and very late stent thrombosis. Should we therefore proscribe DES? How long should be the duration of dual antiplatelet therapy? And how should we manage the patients who need a surgery and are at high risk of bleeding? Are bioresorbable stents the final solution with their initial mechanical properties, then with their drug eluting effect against intra-stent restenosis, and finally with their complete resorption which leaves the artery free of any foreign material?

Gene cluster conservation provides insight into cercosporin biosynthesis and extends production to the genus Colletotrichum.

PubMed

de Jonge, Ronnie; Ebert, Malaika K; Huitt-Roehl, Callie R; Pal, Paramita; Suttle, Jeffrey C; Spanner, Rebecca E; Neubauer, Jonathan D; Jurick, Wayne M; Stott, Karina A; Secor, Gary A; Thomma, Bart P H J; Van de Peer, Yves; Townsend, Craig A; Bolton, Melvin D

2018-06-12

Species in the genus Cercospora cause economically devastating diseases in sugar beet, maize, rice, soy bean, and other major food crops. Here, we sequenced the genome of the sugar beet pathogen Cercospora beticola and found it encodes 63 putative secondary metabolite gene clusters, including the cercosporin toxin biosynthesis ( CTB ) cluster. We show that the CTB gene cluster has experienced multiple duplications and horizontal transfers across a spectrum of plant pathogenic fungi, including the wide-host range Colletotrichum genus as well as the rice pathogen Magnaporthe oryzae Although cercosporin biosynthesis has been thought to rely on an eight-gene CTB cluster, our phylogenomic analysis revealed gene collinearity adjacent to the established cluster in all CTB cluster-harboring species. We demonstrate that the CTB cluster is larger than previously recognized and includes cercosporin facilitator protein, previously shown to be involved with cercosporin autoresistance, and four additional genes required for cercosporin biosynthesis, including the final pathway enzymes that install the unusual cercosporin methylenedioxy bridge. Lastly, we demonstrate production of cercosporin by Colletotrichum fioriniae , the first known cercosporin producer within this agriculturally important genus. Thus, our results provide insight into the intricate evolution and biology of a toxin critical to agriculture and broaden the production of cercosporin to another fungal genus containing many plant pathogens of important crops worldwide. Copyright © 2018 the Author(s). Published by PNAS.

Thermally adapted design strategy of colonial houses in Surabaya

NASA Astrophysics Data System (ADS)

Antaryama, I. G. N.; Ekasiwi, S. N. N.; Mappajaya, A.; Ulum, M. S.

2018-03-01

Colonial buildings, including houses, have been considered as a representation of climate-responsive architecture. The design was thought to be a hybrid model of Dutch and tropical architecture. It was created by way of reinventing tropical and Dutch architecture design principles, and expressed in a new form, i.e. neither resembling Dutch nor tropical building. Aside from this new image, colonial house does show good climatic responses. Previous researches on colonial house generally focus on qualitative assessment of climate performance of the building. Yet this kind of study tends to concentrate on building elements, e.g. wall, window, etc. The present study is designed to give more complete picture of architecture design strategy of the house by exploring and analysing thermal performance of colonial buildings and their related architecture design strategies. Field measurements are conducted during the dry season in several colonial building in Surabaya. Air temperature and humidity are both taken, representing internal and external thermal conditions of the building. These data are then evaluated to determine thermal performance of the house. Finally, various design strategies are examined in order to reveal their significant contributions to its thermal performance. Results of the study in Surabaya confirm findings of the previous researches that are conducted in other locations, which stated that thermal performance of the house is generally good. Passive design strategies such as mass effect and ventilation play an important role in determining performance of the building.

Revisiting hypervelocity stars after Gaia DR2

NASA Astrophysics Data System (ADS)

Boubert, D.; Guillochon, J.; Hawkins, K.; Ginsburg, I.; Evans, N. W.; Strader, J.

2018-06-01

Hypervelocity stars are intriguing rare objects traveling at speeds large enough to be unbound from the Milky Way. Several mechanisms have been proposed for producing them, including the interaction of the Galaxy's super-massive black hole (SMBH) with a binary; rapid mass-loss from a companion to a star in a short-period binary; the tidal disruption of an infalling galaxy and finally ejection from the Large Magellanic Cloud. While previously discovered high-velocity early-type stars are thought to be the result of an interaction with the SMBH, the origin of high-velocity late type stars is ambiguous. The second data release of Gaia (DR2) enables a unique opportunity to resolve this ambiguity and determine whether any late-type candidates are truly unbound from the Milky Way. In this paper, we utilize the new proper motion and velocity information available from DR2 to re-evaluate a collection of historical data compiled on the newly-created Open Fast Stars Catalog. We find that almost all previously-known high-velocity late-type stars are most likely bound to the Milky Way. Only one late-type object (LAMOST J115209.12+120258.0) is unbound from the Galaxy. Performing integrations of orbital histories, we find that this object cannot have been ejected from the Galactic centre and thus may be either debris from the disruption of a satellite galaxy or a disc runaway.

Final Thoughts on Community in Adult ESL

ERIC Educational Resources Information Center

Larrott, Clarena

2009-01-01

Community building is an important, if not essential, element of adult English as a second language (ESL) learning. Communities, whether civic, work, religious, or identity-based, are the contexts within which people cease to be alone and become connected with others. Language is the main tool for communicating with others in communities. For…

Rewarding Work, Priceless Collaborations, Much Gratitude.

PubMed

Simoneau, Guy G

2015-12-01

In this editorial of his final issue as Editor-in-Chief, Dr Guy G. Simoneau shares his thoughts on how changes in the areas of physical therapy research design, professional collaboration, publishing and communication technology, and publication standards played out in the world of JOSPT and recognize the many people who supported and implemented the changes.

The Development and Validation of the Intercultural Sensitivity Scale.

ERIC Educational Resources Information Center

Chen, Guo-Ming; Starosta, William J.

The present study developed and assessed reliability and validity of a new instrument, the Intercultural Sensitivity Scale (ISS). Based on a review of the literature, 44 items thought to be important for intercultural sensitivity were generated. A sample of 414 college students rated these items and generated a 24-item final version of the…

On Ideology: Second Thoughts

ERIC Educational Resources Information Center

Wander, Philip C.

2011-01-01

"Whither ideology?" is an intriguing question, to which the author's immediate response is: Nowhere! Has its moment passed, at least in relation to the way that people ordinarily think of it? Not because the end of ideology has finally come, but because the emergence of the concept in American academic work, as an expression of political…

Research on aviation fuel instability

NASA Technical Reports Server (NTRS)

Baker, C. E.; Bittker, D. A.; Cohen, S. M.; Seng, G. T.

1983-01-01

The underlying causes of fuel thermal degradation are discussed. Topics covered include: nature of fuel instability and its temperature dependence, methods of measuring the instability, chemical mechanisms involved in deposit formation, and instrumental methods for characterizing fuel deposits. Finally, some preliminary thoughts on design approaches for minimizing the effects of lowered thermal stability are briefly discussed.

Motivation, Confidence, and Control; Unraveling Active Learning for Nutrition and Food Undergraduates

ERIC Educational Resources Information Center

Paxman, Jenny R.; Nield, Kevin; Hall, Anna C.

2011-01-01

Abstract: Nutrition and food students at Sheffield Hallam University completed an "active learning" assessment as part of a final year module, Applied Nutrition 2. The purpose of the "active learning" assessment was to encourage and enhance learner autonomy. The assessment consisted of 5 main stages: a briefing, thought shower,…

Constructive Alignment in Economics Teaching: A Reflection on Effective Implementation

ERIC Educational Resources Information Center

McCann, Michael

2017-01-01

The typical approach to student-centred learning in Economics has focused on innovation within the classroom, with little thought given to how this complements teaching and learning and, crucially, assessment. This paper reflects on the implementation of constructive alignment in a final year managerial economics course. It demonstrates how it is…

National Issues Forums: Seniors/Community Connection. Final Report.

ERIC Educational Resources Information Center

Fisher, Suzanne M.

A project was conducted to incorporate the Kettering Foundation's National Issues Forums (NIFs) into two senior citizen centers in Pennsylvania. The NIFs provide a process for sharing thoughts and opinions about areas of pressing national concern in an open exchange of all participants' opinions. An inservice training of senior center staff on…

A Computerized Task Inventory System for Providing Curriculum Content. [Carpentry]. Final Report.

ERIC Educational Resources Information Center

Hill, Clair S.

The pilot study was designed to develop a system for analyzing and providing task inventories for carpentry curriculum development. An initial task inventory of 174 statements was constructed from available published sources, including only those tasks thought to be performed by incumbent workers in residential carpentry in Arizona. The tasks were…

Singing' the Black and Blues

ERIC Educational Resources Information Center

Fisher, Diane

2004-01-01

It is so obvious that the sky is blue in the daytime and black at night, but it took the smartest humans thousands of years of observation, thought, discussion, conjecture, and analysis to finally come up with answers that make scientific sense as to why the sky is these colors. This article discusses light and the scientific research…

National Issues Forums in an ABE Setting. Final Report.

ERIC Educational Resources Information Center

Molek, Carol

National Issues Forums (NIFs) were conducted for adult basic education (ABE) students in a Pennsylvania adult education and job training center. The forums provide a process of sharing thoughts and opinions about areas of pressing national concerns in an open exchange of everyone's opinion. After instructors participated in NIFs, they developed a…

Is positive thinking in anticipation of a performance situation better than distraction? An experimental study in preadolescents.

PubMed

Vassilopoulos, Stephanos P; Brouzos, Andreas; Tsorbatzoudis, Haralambos; Tziouma, Olga

2017-04-01

The current study compares the effects of experimentally induced positive anticipatory thinking and distraction in preadolescents aged 12-13. Eighty-seven participants were instructed to either engage in positive anticipatory thoughts or perform a distraction task while preparing to perform a sporting activity in front of their peers. Results revealed that trait social anxiety was associated with more negative estimates of sport performance and catastrophic thoughts relating to the impending sport activity. Additionally, compared to children who distracted, children in the positive anticipation condition showed significantly increased anxiety levels, more catastrophic thoughts and more negative predictions of sport performance and appearance, although these effects did not appear to interact with trait social anxiety. Finally, no significant manipulation effect on participants' observable behavior was found. The findings further highlight the utility of distracting from an impending, anxiety-provoking situation to keep anxious feelings to a low level. © 2017 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

Is death really the worm at the core? Converging evidence that worldview threat increases death-thought accessibility.

PubMed

Schimel, Jeff; Hayes, Joseph; Williams, Todd; Jahrig, Jesse

2007-05-01

According to terror management theory, if the cultural worldview protects people from thoughts about death, then weakening this structure should increase death-thought accessibility (DTA). Five studies tested this DTA hypothesis. Study 1 showed that threatening Canadian participants' cultural values (vs. those of another culture) increased DTA on a word-fragment completion task. Study 2 showed that when participants could dismiss the threat, DTA remained low. Study 3 replicated the results of Study 1, but DTA was measured using a lexical decision task. Response latencies to death, negative, and neutral content were measured. Worldview threat increased DTA relative to accessibility for negative and neutral content. Study 4 showed that the DTA effect emerged independently of the arousal of anger or anxiety. Finally, Study 5 demonstrated that participants with a pro-creation (vs. pro-evolution) worldview had higher DTA after reading an anti-creation article. Discussion focused on theoretical implications and directions for further research. ((c) 2007 APA, all rights reserved).

Level of Construal, Mind Wandering, and Repetitive Thought

PubMed Central

Watkins, Edward R.

2010-01-01

In this reply to the comment of McVay and Kane (2010)Watkins’s (2008) elaborated control theory informs their perspective on the role of executive control in mind wandering. I argue that although in a number of places the elaborated control theory is consistent with the perspective of McVay and Kane that mind wandering represents a failure of executive control, their account makes a number of claims that are not articulated in the elaborated control theory—most notably, the hypothesis that level of construal moderates entry of thoughts into awareness. Moreover, the relevant literature suggests that the relationship between level of construal and executive control may be more complex, and may be determined by multiple factors beyond those proposed in this executive-control failure account of mind wandering. Finally, the implications of this model of mind wandering for understanding repetitive thought in general are considered, and it is proposed that examining level of executive control as a further moderating variable within elaborated control theory may be of value.

Information presentation format moderates the unconscious-thought effect: The role of recollection.

PubMed

Abadie, Marlène; Waroquier, Laurent; Terrier, Patrice

2016-09-01

The unconscious-thought effect occurs when distraction improves complex decision-making. In two experiments using the unconscious-thought paradigm, we investigated the effect of presentation format of decision information (i) on memory for decision-relevant information and (ii) on the quality of decisions made after distraction, conscious deliberation or immediately. We used the process-dissociation procedure to measure recollection and familiarity. The two studies showed that presenting information blocked per criterion led participants to recollect more decision-relevant details compared to a presentation by option. Moreover, a Bayesian meta-analysis of the two studies provided strong evidence that conscious deliberation resulted in better decisions when the information was presented blocked per criterion and substantial evidence that distraction improved decision quality when the information was presented blocked per option. Finally, Study 2 revealed that the recollection of decision-relevant details mediated the effect of presentation format on decision quality in the deliberation condition. This suggests that recollection contributes to conscious deliberation efficacy.

The Effects of Elaboration on the Strength of Doping-Related Attitudes: Resistance to Change and Behavioral Intentions.

PubMed

Horcajo, Javier; Luttrell, Andrew

2016-06-01

This experiment analyzed whether attitudes toward the legalization of several doping behaviors would resist change and predict behavioral intentions when they were initially formed through thoughtful (i.e., high elaboration) versus nonthoughtful (i.e., low elaboration) processes. Participants were randomly assigned first to a persuasive message either against or in favor of the legalization, which they read with relatively high or low degrees of deliberative thinking. Attitudes and intentions regarding legalization were assessed following that message. Next, each participant received a second message that was opposed to the first one, serving as an attack against the attitude that participants had just formed. Finally, attitudes were again assessed. As hypothesized, participants showed greater attitude-consistent intentions when they formed their initial attitudes through thoughtful (vs. nonthoughtful) consideration of the first message. Moreover, the second message resulted in greater resistance to attitude change when participants formed their initial attitudes through thoughtful (vs. nonthoughtful) processes.

Similar Ratios of Introns to Intergenic Sequence across Animal Genomes

PubMed Central

Wörheide, Gert

2017-01-01

Abstract One central goal of genome biology is to understand how the usage of the genome differs between organisms. Our knowledge of genome composition, needed for downstream inferences, is critically dependent on gene annotations, yet problems associated with gene annotation and assembly errors are usually ignored in comparative genomics. Here, we analyze the genomes of 68 species across 12 animal phyla and some single-cell eukaryotes for general trends in genome composition and transcription, taking into account problems of gene annotation. We show that, regardless of genome size, the ratio of introns to intergenic sequence is comparable across essentially all animals, with nearly all deviations dominated by increased intergenic sequence. Genomes of model organisms have ratios much closer to 1:1, suggesting that the majority of published genomes of nonmodel organisms are underannotated and consequently omit substantial numbers of genes, with likely negative impact on evolutionary interpretations. Finally, our results also indicate that most animals transcribe half or more of their genomes arguing against differences in genome usage between animal groups, and also suggesting that the transcribed portion is more dependent on genome size than previously thought. PMID:28633296

Jealous love and morbid jealousy.

PubMed

Maggini, Carlo; Lundgren, Eva; Leuci, Emanuela

2006-12-01

Jealous love and morbid jealousy, although inextricably linked, cannot be considered the same: jealous love (trait jealousy) is the behavioral and cognitive-affective precondition of morbid jealousy (state jealousy). Love is jealous when it is devoured by the desire for the exclusive and total possession of the partner, whose unconditional and continued presence is avidly requested. This type of love, in addition, is permeated by the need to know what the other is thinking, in order to scrutinize every minimal flaw in the faithfulness of the partner even in his or her innermost thoughts and fantasies; in it, jealousy is virtually always present, even in the absence of a triggering event, because captative love, by its very nature, includes the expectation of a conflict which inevitably actually takes place in reality. Finally, jealousy emerges as an emotional event (jealous flash) in response to a more or less significant change in the behavior of the partner, and reveals to the jealous individual a dimension which was previously latent or inexistent. This intense and brief experience, leaves a more or less blurred memory behind, and tends to progressively repeat itself and take root as a feeling.

Effects of essential oil exposure on salivary estrogen concentration in perimenopausal women.

PubMed

Shinohara, Kazuyuki; Doi, Hirokazu; Kumagai, Chizu; Sawano, Erika; Tarumi, Wataru

2017-01-01

The menopausal transition is the time from the onset of menstrual changes until one year after the final menstrual period. During this phase, perimenopausal women experience a variety of health-related symptoms, which seemingly derive from declining level of estrogen secretion. It has long been recognized that some essential oils have the efficacy of alleviating menopausal symptoms. On the basis of this, it is possible that these essential oils have the potency to facilitate estrogen secretion in women. The present study investigated this possibility by examining if the olfactory exposure to the essential oil increase salivary estrogen concentration. We tested the effect of ten essential oils; clary sage, frankincense, geranium, lavender, jasmine absolute, neroli, rose otto, ylang ylang, orange and roman chamomile, which are thought to relieve perimenopasal symptoms. The results have shown increase of salivary estrogen concentration induced by exposure to geranium and rose otto compared to control odor. Together with the previous studies, the present study may give support to the notion that olfactory exposure to some essential oils can influence salivary concentration of estrogen.

Biomechanical analysis of four different fixations for the posterolateral shearing tibial plateau fracture.

PubMed

Zhang, Wei; Luo, Cong-Feng; Putnis, Sven; Sun, Hui; Zeng, Zhi-Min; Zeng, Bing-Fang

2012-03-01

The posterolateral shearing tibial plateau fracture is uncommon in the literature, however with the increased usage of computer tomography (CT), the incidence of these fractures is no longer as low as previously thought. Few studies have concentrated on this fracture, least of all using a biomechanical model. The purpose of this study was to compare and analyse the biomechanical characteristics of four different types of internal fixation to stabilise the posterolateral shearing tibial plateau fracture. Forty synthetic tibiae (Synbone, right) simulated the posterolateral shearing fracture models and these were randomly assigned into four groups; Group A was fixed with two anterolateral lag screws, Group B with an anteromedial Limited Contact Dynamic Compression Plate (LC-DCP), Group C with a lateral locking plate, and Group D with a posterolateral buttress plate. Vertical displacement of the posterolateral fragment was measured using three different strengths of axial loading force, and finally loaded until fixation failure. It was concluded that the posterolateral buttress plate is biomechanically the strongest fixation method for the posterolateral shearing tibial plateau fracture. Copyright © 2011 Elsevier B.V. All rights reserved.

The different roles of selective autophagic protein degradation in mammalian cells.

PubMed

Wang, Da-wei; Peng, Zhen-ju; Ren, Guang-fang; Wang, Guang-xin

2015-11-10

Autophagy is an intracellular pathway for bulk protein degradation and the removal of damaged organelles by lysosomes. Autophagy was previously thought to be unselective; however, studies have increasingly confirmed that autophagy-mediated protein degradation is highly regulated. Abnormal autophagic protein degradation has been associated with multiple human diseases such as cancer, neurological disability and cardiovascular disease; therefore, further elucidation of protein degradation by autophagy may be beneficial for protein-based clinical therapies. Macroautophagy and chaperone-mediated autophagy (CMA) can both participate in selective protein degradation in mammalian cells, but the process is quite different in each case. Here, we summarize the various types of macroautophagy and CMA involved in determining protein degradation. For this summary, we divide the autophagic protein degradation pathways into four categories: the post-translational modification dependent and independent CMA pathways and the ubiquitin dependent and independent macroautophagy pathways, and describe how some non-canonical pathways and modifications such as phosphorylation, acetylation and arginylation can influence protein degradation by the autophagy lysosome system (ALS). Finally, we comment on why autophagy can serve as either diagnostics or therapeutic targets in different human diseases.

Sedna Orbit Comparisons

NASA Image and Video Library

2004-03-15

These four panels show the location of the newly discovered planet-like object, dubbed "Sedna," which lies in the farthest reaches of our solar system. Each panel, moving counterclockwise from the upper left, successively zooms out to place Sedna in context. The first panel shows the orbits of the inner planets, including Earth, and the asteroid belt that lies between Mars and Jupiter. In the second panel, Sedna is shown well outside the orbits of the outer planets and the more distant Kuiper Belt objects. Sedna's full orbit is illustrated in the third panel along with the object's current location. Sedna is nearing its closest approach to the Sun; its 10,000 year orbit typically takes it to far greater distances. The final panel zooms out much farther, showing that even this large elliptical orbit falls inside what was previously thought to be the inner edge of the Oort cloud. The Oort cloud is a spherical distribution of cold, icy bodies lying at the limits of the Sun's gravitational pull. Sedna's presence suggests that this Oort cloud is much closer than scientists believed. http://photojournal.jpl.nasa.gov/catalog/PIA05569

Polygyny, mate-guarding, and posthumous fertilization as alternative male mating strategies.

PubMed

Zamudio, K R; Sinervo, B

2000-12-19

Alternative male mating strategies within populations are thought to be evolutionarily stable because different behaviors allow each male type to successfully gain access to females. Although alternative male strategies are widespread among animals, quantitative evidence for the success of discrete male strategies is available for only a few systems. We use nuclear microsatellites to estimate the paternity rates of three male lizard strategies previously modeled as a rock-paper-scissors game. Each strategy has strengths that allow it to outcompete one morph, and weaknesses that leave it vulnerable to the strategy of another. Blue-throated males mate-guard their females and avoid cuckoldry by yellow-throated "sneaker" males, but mate-guarding is ineffective against aggressive orange-throated neighbors. The ultradominant orange-throated males are highly polygynous and maintain large territories; they overpower blue-throated neighbors and cosire offspring with their females, but are often cuckolded by yellow-throated males. Finally, yellow-throated sneaker males sire offspring via secretive copulations and often share paternity of offspring within a female's clutch. Sneaker males sire more offspring posthumously, indicating that sperm competition may be an important component of their strategy.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hudson, S.R.

This report presents the results of a four-day symposium which reviewed the state-of-the-art, field testing and recent progress in underground coal conversion. The symposium was held at Keystone Lodge, Colorado, August 15-19, 1982, and was sponsored by the US Department of Energy and hosted by Sandia National Laboratories. Over 100 attendees participated in this seminar which offered more than 60 presentations in both poster and oral sessions on The Status of UCC Technology, Achievements and Problems of UCC, Future R and D Activities, and Roles and Outlooks, for an overall theme of Where Do We Go From Here. This symposiummore » was structured to deal with an evaluation of the present uncertainty in future federal funding of UCC. Panel discussions were held after each oral session to address this overall question. The final session of the symposium was a summary session reflecting the thoughts of all panelists and symposium speakers. This session also serves as our Executive Summary (page 567). Forty-one papers have been entered individually into EDB and ERA; twelve papers had been entered previously. (LTN)« less

[Fake drugs, what are we talking about? Counterfeit drugs, informal market, quality of pharmaceutical… Thought from an anthropological study led in Benin].

PubMed

Baxerres, C

2014-05-01

This paper questions the current highlighted question of "fake drugs" in the media and through institutional speeches. After a brief reminder of the expressions used previously in France and in the French-speaking countries of West Africa, the realities which recover various phenomena will be discussed as well as the hotchpotch often made between them: the phenomenon of counterfeit drugs, that of substandard medicines and the recently legally defined in Europe phenomenon of falsified drugs. Then, the data of an anthropological study led from 2005 till 2007 about the informal market of pharmaceutical in Benin will allow to underline the differences which exist between this phenomenon and that of counterfeit drugs as well as that of falsified drugs. Finally, the political and economic stakes which recover these questions will be highlighted and will explain why "fantasized" speeches are often given about them. The conclusion will stop on the problem of substandard medicines and some of the ways to solve it will be sketched.

Sedna Orbit Comparisons

NASA Technical Reports Server (NTRS)

2004-01-01

These four panels show the location of the newly discovered planet-like object, dubbed 'Sedna,' which lies in the farthest reaches of our solar system. Each panel, moving counterclockwise from the upper left, successively zooms out to place Sedna in context. The first panel shows the orbits of the inner planets, including Earth, and the asteroid belt that lies between Mars and Jupiter. In the second panel, Sedna is shown well outside the orbits of the outer planets and the more distant Kuiper Belt objects. Sedna's full orbit is illustrated in the third panel along with the object's current location. Sedna is nearing its closest approach to the Sun; its 10,000 year orbit typically takes it to far greater distances. The final panel zooms out much farther, showing that even this large elliptical orbit falls inside what was previously thought to be the inner edge of the Oort cloud. The Oort cloud is a spherical distribution of cold, icy bodies lying at the limits of the Sun's gravitational pull. Sedna's presence suggests that this Oort cloud is much closer than scientists believed.

Electron Matter Optics and the Quantum Electron Stern-Gerlach Magnet

NASA Astrophysics Data System (ADS)

McGregor, Scot; Bach, Roger; Yin, Xiaolu; Liou, Sy-Hwang; Batelaan, Herman; Gronniger, Glen

2011-05-01

We explore electron interferometry for the purpose of performing fundamental quantum mechanical experiments and sensing applications. To this end electron matter optics elements, in particular, a diffraction limited single slit, a double slit, and a nano-fabricated grating diffraction apparatus as well as a Mach-Zehnder IFM were previously developed. The double slit diffraction pattern has been recorded one electron at a time. Furthermore, the capability of closing each slit on demand has been developed, in that way realizing the thought experiment that Feynman explains in his lectures. The capability of the Mach-Zehnder interferometer to sense DC and AC electromagnetic fields for industrial applications is currently under investigation. Also, the construction of a new type of interferometer that has the potential to significantly increase the enclosed area and thus its sensitivity is in progress. Finally an idea to separate an electron beam fully into its two spin component using an electron interferometer is presented. We gratefully acknowledge funding by NSF Grant No. 0969506 and R. B. and S. M. acknowledge DOE-GAANN fellowships.

Impulsive Choice in Mice Lacking Paternal Expression of Grb10 Suggests Intragenomic Conflict in Behavior.

PubMed

Dent, Claire L; Humby, Trevor; Lewis, Katie; Ward, Andrew; Fischer-Colbrie, Reiner; Wilkinson, Lawrence S; Wilkins, Jon F; Isles, Anthony R

2018-05-01

Imprinted genes are expressed from one parental allele only as a consequence of epigenetic events that take place in the mammalian germ line and are thought to have evolved through intragenomic conflict between parental alleles. We demonstrate, for the first time, oppositional effects of imprinted genes on brain and behavior. Specifically, we show that mice lacking paternal Grb10 make fewer impulsive choices, with no dissociable effects on a separate measure of impulsive action. Taken together with previous work showing that mice lacking maternal Nesp55 make more impulsive choices, this suggests that impulsive choice behavior is a substrate for the action of genomic imprinting. Moreover, the contrasting effect of these two genes suggests that impulsive choices are subject to intragenomic conflict and that maternal and paternal interests pull this behavior in opposite directions. Finally, these data may also indicate that an imbalance in expression of imprinted genes contributes to pathological conditions such as gambling and drug addiction, where impulsive behavior becomes maladaptive. Copyright © 2018 Dent et al.

Biliary Fasciola gigantica infestation in a nonendemic area--An intraoperative surprise.

PubMed

Menon, Prema; Sinha, Amit Kumar; Rao, Katragadda Lakshmi Narasimha; Khurana, Sumeeta; Lal, Sadhana; Thapa, Babu Ram

2015-11-01

A 7year old girl infected with the zoonotic trematode, Fasciola gigantica is reported because of the extreme rarity of this condition in our region. Because of the overlap in symptomatology and radiological features, the more common amebic/pyogenic liver abscess in the initial hepatic migratory phase and later choledochal cyst/biliary ascariasis when the parasite was finally located in the extrahepatic bile ducts, were thought of delaying effective treatment. The diagnosis was confirmed only by surgical exploration. The characteristic contrast enhanced computed tomography scan features retrospectively identified were multiple clustered hypodense lesions in the liver with peripheral enhancement in the acute hepatic migratory phase, and periportal tracking in the previously affected areas of the liver with biliary dilatation and a linear hypointense lesion within the common bile duct in the chronic phase. Although a known association, she did not have eosinophilia. This child, who became symptomatic at the age of 5.5years, also appears to be one of the youngest patients reported with Fasciola gigantica. Copyright © 2015 Elsevier Inc. All rights reserved.

Comprehensive global genome dynamics of Chlamydia trachomatis show ancient diversification followed by contemporary mixing and recent lineage expansion.

PubMed

Hadfield, James; Harris, Simon R; Seth-Smith, Helena M B; Parmar, Surendra; Andersson, Patiyan; Giffard, Philip M; Schachter, Julius; Moncada, Jeanne; Ellison, Louise; Vaulet, María Lucía Gallo; Fermepin, Marcelo Rodríguez; Radebe, Frans; Mendoza, Suyapa; Ouburg, Sander; Morré, Servaas A; Sachse, Konrad; Puolakkainen, Mirja; Korhonen, Suvi J; Sonnex, Chris; Wiggins, Rebecca; Jalal, Hamid; Brunelli, Tamara; Casprini, Patrizia; Pitt, Rachel; Ison, Cathy; Savicheva, Alevtina; Shipitsyna, Elena; Hadad, Ronza; Kari, Laszlo; Burton, Matthew J; Mabey, David; Solomon, Anthony W; Lewis, David; Marsh, Peter; Unemo, Magnus; Clarke, Ian N; Parkhill, Julian; Thomson, Nicholas R

2017-07-01

Chlamydia trachomatis is the world's most prevalent bacterial sexually transmitted infection and leading infectious cause of blindness, yet it is one of the least understood human pathogens, in part due to the difficulties of in vitro culturing and the lack of available tools for genetic manipulation. Genome sequencing has reinvigorated this field, shedding light on the contemporary history of this pathogen. Here, we analyze 563 full genomes, 455 of which are novel, to show that the history of the species comprises two phases, and conclude that the currently circulating lineages are the result of evolution in different genomic ecotypes. Temporal analysis indicates these lineages have recently expanded in the space of thousands of years, rather than the millions of years as previously thought, a finding that dramatically changes our understanding of this pathogen's history. Finally, at a time when almost every pathogen is becoming increasingly resistant to antimicrobials, we show that there is no evidence of circulating genomic resistance in C. trachomatis . © 2017 Hadfield et al.; Published by Cold Spring Harbor Laboratory Press.

Perceptions, use and attitudes of pharmacy customers on complementary medicines and pharmacy practice.

PubMed

Braun, Lesley A; Tiralongo, Evelin; Wilkinson, Jenny M; Spitzer, Ondine; Bailey, Michael; Poole, Susan; Dooley, Michael

2010-07-20

Complementary medicines (CMs) are popular amongst Australians and community pharmacy is a major supplier of these products. This study explores pharmacy customer use, attitudes and perceptions of complementary medicines, and their expectations of pharmacists as they relate to these products. Pharmacy customers randomly selected from sixty large and small, metropolitan and rural pharmacies in three Australian states completed an anonymous, self administered questionnaire that had been pre-tested and validated. 1,121 customers participated (response rate 62%). 72% had used CMs within the previous 12 months, 61% used prescription medicines daily and 43% had used both concomitantly. Multivitamins, fish oils, vitamin C, glucosamine and probiotics were the five most popular CMs. 72% of people using CMs rated their products as 'very effective' or 'effective enough'. CMs were as frequently used by customers aged 60 years or older as younger customers (69% vs. 72%) although the pattern of use shifted with older age. Most customers (92%) thought pharmacists should provide safety information about CMs, 90% thought they should routinely check for interactions, 87% thought they should recommend effective CMs, 78% thought CMs should be recorded in customer's medication profile and 58% thought pharmacies stocking CMs should also employ a complementary medicine practitioner. Of those using CMs, 93% thought it important for pharmacists to be knowledgeable about CMs and 48% felt their pharmacist provides useful information about CMs. CMs are widely used by pharmacy customers of all ages who want pharmacists to be more involved in providing advice about these products.

Self-efficacy for controlling upsetting thoughts and emotional eating in family caregivers.

PubMed

MacDougall, Megan; Steffen, Ann

2017-10-01

Self-efficacy for controlling upsetting thoughts was examined as a predictor of emotional eating by family caregivers of physically and cognitively impaired older adults. Adult women (N = 158) providing healthcare assistance for an older family member completed an online survey about caregiving stressors, depressive symptoms, self-efficacy, and emotional eating. A stress process framework was used as a conceptual model to guide selection of variables predicting emotional eating scores. A hierarchical multiple regression was conducted and the overall model was significant (R 2 = .21, F(4,153) = 10.02, p < .01); self-efficacy for controlling upsetting thoughts was a significant predictor of caregivers' emotional eating scores after accounting for IADL, role overload, and depression scores. These findings replicate previous research demonstrating the relationship between managing cognitions about caregiving and behavioral responses to stressors, and point to the importance of addressing cognitive processes in efforts to improve caregiver health behaviors.

Theory of mind performance in schizophrenia: diagnostic, symptom, and neuropsychological correlates.

PubMed

Greig, Tamasine C; Bryson, Gary J; Bell, Morris D

2004-01-01

The purpose of this study was to explore the relationship between Theory of Mind (ToM) performance and schizophrenia subtype, symptom, and neuropsychological variables. One hundred twenty-eight stable outpatients with schizophrenia or schizoaffective disorder were assessed during the intake phase of a vocational and cognitive rehabilitation study. Results indicate that ToM performance differed significantly by schizophrenia diagnosis, with people diagnosed with disorganized schizophrenia performing the most poorly. Theory of Mind performance was also significantly correlated with measures of thought disorder and verbal memory. Regression analysis revealed that thought disorder and verbal memory measures explained 30% of the variance in ToM scores. Findings suggest that there is theory of mind variance in the schizophrenia population and theory of mind is strongly related to thought disorder, verbal memory, and cognitive disorganization. Contrary to previous reports, ToM was not related to measures of paranoia.

Why consent may not be needed for organ procurement.

PubMed

Delaney, James; Hershenov, David B

2009-08-01

Most people think it is wrong to take organs from the dead if the potential donors had previously expressed a wish not to donate. Yet people respond differently to a thought experiment that seems analogous in terms of moral relevance to taking organs without consent. We argue that our reaction to the thought experiment is most representative of our deepest moral convictions. We realize not everyone will be convinced by the conclusions we draw from our thought experiment. Therefore, we point out that the state ignores consent in performing mandatory autopsies in some cases. If readers are willing to give up the permissibility of mandatory autopsies, we then offer some metaphysical arguments against posthumous harm. Drawing upon claims about bodies ceasing to exist at death and Epicurean-inspired arguments against posthumous interests, we make a case for an organ conscription policy which respects fundamental liberal principles of autonomy, bodily integrity, and property.

For Which Side the Bell Tolls: The Laterality of Approach-Avoidance Associative Networks.

PubMed

Fetterman, Adam K; Ode, Scott; Robinson, Michael D

2013-03-01

The two hemispheres of the brain appear to play different roles in emotion and/or motivation. A great deal of previous research has examined the valence hypothesis (left hemisphere = positive; right = negative), but an increasing body of work has supported the motivational hypothesis (left hemisphere = approach; right = avoidance) as an alternative. The present investigation ( N = 117) sought to provide novel support for the latter perspective. Left versus right hemispheres were briefly activated by neutral lateralized auditory primes. Subsequently, participants categorized approach versus avoidance words as quickly and accurately as possible. Performance in the task revealed that approach-related thoughts were more accessible following left-hemispheric activation, whereas avoidance-related thoughts were more accessible following right-hemispheric activation. The present results are the first to examine such lateralized differences in accessible motivational thoughts, which may underlie more "downstream" manifestations of approach and avoidance motivation such as judgments, decision making, and behavior.

For Which Side the Bell Tolls: The Laterality of Approach-Avoidance Associative Networks

PubMed Central

Fetterman, Adam K.; Ode, Scott; Robinson, Michael D.

2012-01-01

The two hemispheres of the brain appear to play different roles in emotion and/or motivation. A great deal of previous research has examined the valence hypothesis (left hemisphere = positive; right = negative), but an increasing body of work has supported the motivational hypothesis (left hemisphere = approach; right = avoidance) as an alternative. The present investigation (N = 117) sought to provide novel support for the latter perspective. Left versus right hemispheres were briefly activated by neutral lateralized auditory primes. Subsequently, participants categorized approach versus avoidance words as quickly and accurately as possible. Performance in the task revealed that approach-related thoughts were more accessible following left-hemispheric activation, whereas avoidance-related thoughts were more accessible following right-hemispheric activation. The present results are the first to examine such lateralized differences in accessible motivational thoughts, which may underlie more “downstream” manifestations of approach and avoidance motivation such as judgments, decision making, and behavior. PMID:23869114

Hereditary Spastic Paraplegia-Linked REEP1 Modulates ER-Mitochondria Contacts

PubMed Central

Lim, Youngshin; Cho, Il-Taeg; Schoel, Leah J.; Cho, Ginam; Golden, Jeffrey A.

2015-01-01

Objective Mutations in receptor expression enhancing protein 1 (REEP1) are associated with hereditary spastic paraplegias (HSPs). Although axonal degeneration is thought to be a predominant feature in HSP, the role of REEP1 mutations in degeneration is largely unknown. Previous studies have implicated a role for REEP1 in the ER, whereas others localized REEP1 with mitochondria. We sought to resolve the cellular localization of REEP1 and to further elucidate the pathobiology underlying REEP1 mutations in patients. Methods A combination of cellular imaging and biochemical approaches was used to refine the cellular localization of REEP1. Next, Reep1 mutations associated with HSP were functionally tested in neuritic growth and degeneration assays using mouse cortical culture. Finally, a novel assay was developed and used with wild type and mutant Reep1s to measure the interactions between the ER and mitochondria. Results We found that REEP1 is present at the ER-mitochondria interface, and it contains subdomains for mitochondrial as well as ER localization. Knockdown of Reep1 and the expression of pathological Reep1 mutations resulted in neuritic growth defects and degeneration. Finally, using our novel split-RLuc8 assay, we show REEP1 facilitates ER-mitochondria interactions, a function diminished by disease-associated mutations. Interpretation Our data potentially reconcile the current conflicting reports regarding REEP1 being either an ER or a mitochondrial protein. Furthermore, our results connect, for the first time, the disrupted ER-mitochondria interactions to a failure in maintaining health of long axons in HSPs. Finally, the split-RLuc8 assay offers a new tool to identify potential drugs for multiple neurodegenerative diseases with ER-mitochondria interaction defects. PMID:26201691

Intrapersonal positive future thinking predicts repeat suicide attempts in hospital-treated suicide attempters.

PubMed

O'Connor, Rory C; Smyth, Roger; Williams, J Mark G

2015-02-01

Although there is clear evidence that low levels of positive future thinking (anticipation of positive experiences in the future) and hopelessness are associated with suicide risk, the relationship between the content of positive future thinking and suicidal behavior has yet to be investigated. This is the first study to determine whether the positive future thinking-suicide attempt relationship varies as a function of the content of the thoughts and whether positive future thinking predicts suicide attempts over time. A total of 388 patients hospitalized following a suicide attempt completed a range of clinical and psychological measures (depression, hopelessness, suicidal ideation, suicidal intent and positive future thinking). Fifteen months later, a nationally linked database was used to determine who had been hospitalized again after a suicide attempt. During follow-up, 25.6% of linked participants were readmitted to hospital following a suicide attempt. In univariate logistic regression analyses, previous suicide attempts, suicidal ideation, hopelessness, and depression-as well as low levels of achievement, low levels of financial positive future thoughts, and high levels of intrapersonal (thoughts about the individual and no one else) positive future thoughts predicted repeat suicide attempts. However, only previous suicide attempts, suicidal ideation, and high levels of intrapersonal positive future thinking were significant predictors in multivariate analyses. Positive future thinking has predictive utility over time; however, the content of the thinking affects the direction and strength of the positive future thinking-suicidal behavior relationship. Future research is required to understand the mechanisms that link high levels of intrapersonal positive future thinking to suicide risk and how intrapersonal thinking should be targeted in treatment interventions. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

Intrapersonal Positive Future Thinking Predicts Repeat Suicide Attempts in Hospital-Treated Suicide Attempters

PubMed Central

2014-01-01

Objective: Although there is clear evidence that low levels of positive future thinking (anticipation of positive experiences in the future) and hopelessness are associated with suicide risk, the relationship between the content of positive future thinking and suicidal behavior has yet to be investigated. This is the first study to determine whether the positive future thinking–suicide attempt relationship varies as a function of the content of the thoughts and whether positive future thinking predicts suicide attempts over time. Method: A total of 388 patients hospitalized following a suicide attempt completed a range of clinical and psychological measures (depression, hopelessness, suicidal ideation, suicidal intent and positive future thinking). Fifteen months later, a nationally linked database was used to determine who had been hospitalized again after a suicide attempt. Results: During follow-up, 25.6% of linked participants were readmitted to hospital following a suicide attempt. In univariate logistic regression analyses, previous suicide attempts, suicidal ideation, hopelessness, and depression—as well as low levels of achievement, low levels of financial positive future thoughts, and high levels of intrapersonal (thoughts about the individual and no one else) positive future thoughts predicted repeat suicide attempts. However, only previous suicide attempts, suicidal ideation, and high levels of intrapersonal positive future thinking were significant predictors in multivariate analyses. Discussion: Positive future thinking has predictive utility over time; however, the content of the thinking affects the direction and strength of the positive future thinking–suicidal behavior relationship. Future research is required to understand the mechanisms that link high levels of intrapersonal positive future thinking to suicide risk and how intrapersonal thinking should be targeted in treatment interventions. PMID:25181026

Work environment and recent suicidal thoughts among male university hospital physicians in Sweden and Italy: the health and organization among university hospital physicians in Europe (HOUPE) study.

PubMed

Fridner, Ann; Belkić, Karen; Minucci, Daria; Pavan, Luigi; Marini, Massimo; Pingel, Birgit; Putoto, Giovanni; Simonato, Pierluigi; Løvseth, Lise T; Schenck-Gustafsson, Karin

2011-08-01

Male and female physicians are at elevated suicide risk. The work environment has become a focus of attention as a possible contributor to this risk. The potential association between work environment and suicidal thoughts has been examined among female physicians in several countries, and significant findings have been reported. The purpose of this study was to examine the role of the work environment in relation to suicidal thoughts among male university hospital physicians in 2 European countries. Cross-sectional multivariate analysis was performed to identify significant associations between work-related factors and suicide risk among male physicians from the Health and Organization among University Hospital Physicians in Europe (HOUPE) study. The dependent variable was termed recent suicidal thoughts, which includes having thought about suicide and/or having thought about specific ways to commit suicide within the previous year. Adjusted odds ratios (ORs) and CIs are reported. Of the 456 Swedish (56%) and 241 Italian (39%) male physicians who participated, 12% of the physicians from each country reported affirmatively regarding recent suicidal thoughts. Degrading work experiences were associated with recent suicidal thoughts for the Swedish and Italian physicians (OR = 2.1; 95% CI, 1.01-4.5; OR = 3.3; 95% CI, 1.3-8.0, respectively). Role conflict was associated with recent suicidal thoughts among the Swedish physicians (OR = 1.6; 95% CI, 1.1-2.2). Support at work when difficulties arose appeared to be protective for the Swedish physicians (OR = 0.7; 95% CI, 0.5-0.96). Italian physicians with little control over working conditions had an increased risk of recent suicidal thoughts, whereas confidential discussions about work experiences appeared to be protective (OR = 0.6; 95% CI, 0.4-0.9). Attention should be paid to the work environment as it relates to suicide risk among male university hospital physicians, particularly to bolstering social support and preventing harassment. Copyright © 2011 Elsevier HS Journals, Inc. All rights reserved.

AN ENRICHMENT CULTURE THAT DEGRADES MTBE UNDER ANAEROBIC CONDITIONS

EPA Science Inventory

Biodegradation of MTBE in ground water may be a significant factor helping to reduce MTBE contamination from gasoline spills. Previously, decreases in MTBE concentrations in wells at release sites were thought to be due exclusively to dispersion and dilution. Researchers have i...

A Neo-Cognitive Dimension.

ERIC Educational Resources Information Center

Suarez, E. M.

1988-01-01

Responds to Mahoney and Lyddon's review of constructivism in previous article by focusing on developments emerged from work with Neo-Cognitive Psychotherapy that add new and necessary dimension to issues of agency and constructivism. Presents neo-cognitive view of thought and discusses the evolution of understanding. (NB)

Tainted Water, Poison Paint.

ERIC Educational Resources Information Center

Natale, Jo Anna

1991-01-01

Recent research shows lead poisoning is more widespread and even more dangerous to infants and young children than previously thought. A bill proposed in Congress would require schools and day-care centers to test for lead. Summarizes lead's health hazards and how to test drinking water. (MLF)

Distribution of Areal Strain on Mercury: Insights into the Interaction of Volcanism and Global Contraction

NASA Astrophysics Data System (ADS)

Peterson, G. A.; Johnson, C. L.; Byrne, P. K.; Phillips, R. J.

2018-05-01

Wrinkle ridges within volcanic plains on Mercury host just as much shortening strain as lobate scarps and high relief ridges, suggesting that wrinkle ridges have accommodated much more strain from global contraction than previously thought.

Helping victims of modern slavery.

PubMed

Cahill, Louise

2017-05-17

I was volunteering at a refugee centre when a woman told me she was the happiest she could remember being. She said she had previously been a slave, and no matter how bad I thought her situation was now, it was always better than her past.

Offline memory reprocessing: involvement of the brain's default network in spontaneous thought processes.

PubMed

Wang, Kun; Yu, Chunshui; Xu, Lijuan; Qin, Wen; Li, Kuncheng; Xu, Lin; Jiang, Tianzi

2009-01-01

Spontaneous thought processes (STPs), also called daydreaming or mind-wandering, occur ubiquitously in daily life. However, the functional significance of STPs remains largely unknown. Using functional magnetic resonance imaging (fMRI), we first identified an STPs-network whose activity was positively correlated with the subjects' tendency of having STPs during a task-free state. The STPs-network was then found to be strongly associated with the default network, which has previously been established as being active during the task-free state. Interestingly, we found that offline reprocessing of previously memorized information further increased the activity of the STPs-network regions, although during a state with less STPs. In addition, we found that the STPs-network kept a dynamic balance between functional integration and functional separation among its component regions to execute offline memory reprocessing in STPs. These findings strengthen a view that offline memory reprocessing and STPs share the brain's default network, and thus implicate that offline memory reprocessing may be a predetermined function of STPs. This supports the perspective that memory can be consolidated and modified during STPs, and thus gives rise to a dynamic behavior dependent on both previous external and internal experiences.

"Finding Foucault": Orders of Discourse and Cultures of the Self

ERIC Educational Resources Information Center

Besley, A. C.

2015-01-01

The idea of finding Foucault first looks at the many influences on Foucault, including his Nietzschean acclamations. It examines Foucault's critical history of thought, his work on the orders of discourse with his emphasis on being a pluralist: the problem he says that he has set himself is that of the individualization of discourses. Finally, it…

The repeatability of stem exclusion during even-aged development of bigtooth aspen dominated forests

Treesearch

Brain J. Palik; Kurt S. Pregitzer

1993-01-01

Forest development following major disturbance is thought to follow a fairly repeatable temporal pattern. An initial cohort of trees establishes relatively rapidly (stand initiation), new establishment is precluded for an extended period (stem exclusion), and finally, new individuals again begin to establish, creating new age-classes in the forest understory (...

Taoism and Its Implications for Science Education.

ERIC Educational Resources Information Center

Hua, Hsiao-Peng; Chang, Chun-Yen; MacRaven, Maggie Maeve

As one of the major schools of thought in ancient China, Taoism centers on the concept of "Tao", the Way, which has two distinct characteristics: (1) Tao itself can be deemed as a final "reality" that is equivalent to the ontology of the Universe; and (2) Tao itself cannot be defined directly by human language. Taoism posits a holistically…

A Closer Look at Chinese EFL Learners' Test-Wiseness Strategies in Reading Test

ERIC Educational Resources Information Center

Haiyan, Miao; Rilong, Liu

2016-01-01

This paper reports on an investigation into the relationship of test-takers' use of test-wiseness strategies to Chinese EFL learners' reading test performance. A test-wiseness questionnaire was administered immediately after the final achievement test to probe into how learners thought while completing the reading section of the test. It was found…

Risk Factors for Sexual Violence in the Military: An Analysis of Sexual Assault and Sexual Harassment Incidents and Reporting

DTIC Science & Technology

2017-03-01

53 ix LIST OF TABLES Table 1. Descriptive Statistics for Control Variables by... Statistics for Control Variables by Gender (Random Subsample with Complete Survey) ............................................................30 Table...empirical analysis. Chapter IV describes the summary statistics and results. Finally, Chapter V offers concluding thoughts, study limitations, and

Analysis of the Final Report of the Fundamental Science Review: A Blueprint for Research, A Call for Action

ERIC Educational Resources Information Center

Canadian Association of University Teachers, 2017

2017-01-01

Canadian Association of University Teachers (CAUT) welcomes the report of the Advisory Panel on Federal Support for Fundamental Science "the Panel". It is a thoughtful and comprehensive study that correctly diagnoses problems that have plagued basic science for over a decade. The Panel's recommendations, if implemented, will chart a…

The Common Good in Classical Political Philosophy

ERIC Educational Resources Information Center

Lewis, V. Bradley

2006-01-01

The term "common good" names the end (or final cause) of political and social life in the tradition of moral thought that owes its main substance to Aristotle and St. Thomas Aquinas. It names a genuine good ("bonum honestum") and not merely an instrumental or secondary good defeasible in the face of particular goods. However, at the same time, it…

Improving Teaching Does Improve Teachers: Evidence from Lesson Study

ERIC Educational Resources Information Center

Lewis, Catherine C.; Perry, Rebecca R.; Friedkin, Shelley; Roth, Jillian R.

2012-01-01

The authors comment on the article by Morris and Hiebert in three ways. First, they add thoughts about why improvement efforts often focus on teachers, rather than teaching. Second, they offer evidence from U.S. lesson study research that focus on teaching can improve both students' learning and teachers' learning. Finally, they suggest that the…

Examining the impact of thought substitution on intentional forgetting in induced and naturally occurring dysphoria.

PubMed

Noreen, Saima; Ridout, Nathan

2016-07-30

Two experiments were conducted to determine if natural and induced dysphoria is associated with impaired forgetting and, whether a thought-substitution strategy would ameliorate any observed deficits. Study 1: 36 dysphoric & 36 non-dysphoric participants learnt a series of emotional word pairs. Participants were subsequently presented with some of the cues and were asked to recall the targets or prevent the targets from coming to mind. Half of the participants were provided with substitute words to recall instead of the original targets (aided suppression). At final memory testing, participants were asked to recall the targets to all cues. Dysphoric participants exhibited impaired forgetting, even when using a thought substitution strategy. Non-dysphoric participants, however, were able to use substitutes to suppress words. Study 2: 50 healthy participants initially completed the aided condition of the forgetting task. Participants were then given a positive or negative mood-induction, followed by another version of the forgetting task. Although all participants showed a forgetting effect prior to the mood-induction, only the positive group was successful at forgetting after the mood induction. Taken together, these findings do not support the utility of thought-substitution as an aid to forgetting in individuals in a naturally or induced dysphoric mood. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

The effect of the Baton Rouge fault on flow in the Abita aquifer of southeastern Louisiana

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rapp, T.R.

1993-03-01

The ground-water resources of southern Tangipahoa Parish and adjacent areas were studied to determine their potential for development as an alternative to the Mississippi River as a water supply source for Jefferson Parish, Louisiana. The study area, in southeastern Louisiana, is underlain by eight major aquifers and is crossed by a fault zone, referred to as the Baton Rouge fault. The fault restricts the flow of water in the aquifers of intermediate depth. Data from a test well drilling program and geophysical logs of a nearby oil well indicated that a significant freshwater aquifer that provides water to a nearbymore » municipality was actually the Abita aquifer and not the Covington aquifer, as was previously thought. The Abita aquifer, a shallower aquifer with a lower hydraulic conductivity, had been displaced to a position equivalent to that of the Covington aquifer by the Baton Rouge fault. An additional final test well drilled south of the fault penetrated the leading edge of a wedge-shaped saltwater interface. Analysis of lithologic and geophysical logs indicated that the Abita aquifer has a well-sorted, clean sand at the base of the aquifer and substantial amounts of clay in the top two-thirds of the aquifer. Geophysical logs of oil test wells south of the fault zone indicated that the sand thickens substantially to the south. The thicker sand south of a public supply well that pumps water from the Abita aquifer and the higher hydraulic conductivity of the lower part of the aquifer where the saline water was detected indicate that a much larger percentage of recharge to the public supply well may come from the south than was originally thought.« less

Medical, demographic and psychological correlates of fear of cancer recurrence (FCR) morbidity in breast, colorectal and melanoma cancer survivors with probable clinically significant FCR seeking psychological treatment through the ConquerFear study.

PubMed

Smith, Allan 'Ben'; Sharpe, Louise; Thewes, Belinda; Turner, Jane; Gilchrist, Jemma; Fardell, Joanna E; Girgis, Afaf; Tesson, Stephanie; Descallar, Joseph; Bell, Melanie L; Beith, Jane; Butow, Phyllis

2018-06-07

Despite the prevalence of fear of cancer recurrence (FCR), understanding of factors underlying clinically significant FCR is limited. This study examined factors associated with greater FCR morbidity, according to a cognitive processing model, in cancer survivors who screened positively for clinically significant FCR seeking psychological treatment through the ConquerFear trial. Participants had completed treatment for breast, colorectal or melanoma cancer 2 months to 5 years previously and scored ≥ 13/36 on the Fear of Cancer Recurrence Inventory-Short Form (FCRI-SF). Hierarchical regression analyses examined associations between demographic, medical and psychological variables, namely metacognitions (MCQ-30), post-traumatic stress symptoms (IES-R) and FCR (FCRI total score). Two hundred and ten (95%) of the 222 cancer survivors who consented to the ConquerFear trial completed the baseline questionnaire. Participants were predominantly (89%) breast cancer survivors. The final regression model accounted for 68% of the variance in FCR (demographic and medical variables 13%, metacognitions 26%, post-traumatic stress symptoms 28%). Negative metacognitive beliefs about worry and intrusive post-traumatic stress symptoms were significant individual correlates of FCR, but negative beliefs about worry did not significantly moderate the impact of intrusions on FCR morbidity. Results provide partial support for the cognitive processing model of FCR. Psychological factors were found to play an important role in FCR morbidity after controlling for demographic/medical factors. More intrusive thoughts and negative beliefs about worry were strong independent predictors of FCR morbidity. Cancer survivors with clinically significant FCR may benefit from assessment for intrusive thoughts and metacognitions and delivery of trauma- and/or metacognitive-based interventions accordingly.

Specific TATAA and bZIP requirements suggest that HTLV-I Tax has transcriptional activity subsequent to the assembly of an initiation complex

PubMed Central

Ching, Yick-Pang; Chun, Abel CS; Chin, King-Tung; Zhang, Zhi-Qing; Jeang, Kuan-Teh; Jin, Dong-Yan

2004-01-01

Background Human T-cell leukemia virus type I (HTLV-I) Tax protein is a transcriptional regulator of viral and cellular genes. In this study we have examined in detail the determinants for Tax-mediated transcriptional activation. Results Whereas previously the LTR enhancer elements were thought to be the sole Tax-targets, herein, we find that the core HTLV-I TATAA motif also provides specific responsiveness not seen with either the SV40 or the E1b TATAA boxes. When enhancer elements which can mediate Tax-responsiveness were compared, the authentic HTLV-I 21-bp repeats were found to be the most effective. Related bZIP factors such as CREB, ATF4, c-Jun and LZIP are often thought to recognize the 21-bp repeats equivalently. However, amongst bZIP factors, we found that CREB, by far, is preferred by Tax for activation. When LTR transcription was reconstituted by substituting either κB or serum response elements in place of the 21-bp repeats, Tax activated these surrogate motifs using surfaces which are different from that utilized for CREB interaction. Finally, we employed artificial recruitment of TATA-binding protein to the HTLV-I promoter in "bypass" experiments to show for the first time that Tax has transcriptional activity subsequent to the assembly of an initiation complex at the promoter. Conclusions Optimal activation of the HTLV-I LTR by Tax specifically requires the core HTLV-I TATAA promoter, CREB and the 21-bp repeats. In addition, we also provide the first evidence for transcriptional activity of Tax after the recruitment of TATA-binding protein to the promoter. PMID:15285791

A New Look at Mars

ERIC Educational Resources Information Center

Veverka, J.

1973-01-01

The Mariner 9 mission has shown that surface changes, thought previously to be a by-product of some form of life, are intimately connected to strong Martian winds which scour the surface. Close-up photographs of the two moons dispel the notion that they are artificial satellites. (DF)

Father-son incest: underreported psychiatric problem?

PubMed

Dixon, K N; Arnold, L E; Calestro, K

1978-07-01

Six families are described in which 10 sons were involved incestuously with a natural father (N=4) or step-father (N=2). Father-son incest as a part of the spectrum of child abuse appears to be a more frequent clinical entity than was thought previously.

Time for Gas Planets to Grow

NASA Technical Reports Server (NTRS)

Lissauer, Jack J.; DeVincenzi, Donald (Technical Monitor)

2001-01-01

Giant planets like Jupiter need a large reservoir of gas to grow to full size. New observations indicate that such planetary nurseries last twice as long as previously thought. These observations, and their implications for the abundance of Jupiter-like planets within our galaxy, are discussed herein.

Active Galactic Nucleus

NASA Image and Video Library

2017-09-14

SCI2017_0007: Artist illustration of the thick ring of dust that can obscure the energetic processes that occur near the supermassive black hole of an active galactic nuclei. The SOFIA studies suggest that the dust distribution is about 30 percent smaller than previously thought. Credit: NASA/SOFIA/Lynette Cook

Cooling flows and X-ray emission in early-type galaxies

NASA Technical Reports Server (NTRS)

Sarazin, Craig L.

1990-01-01

The X-ray properties of normal early-type galaxies and the limited theoretical understanding of the physics of the hot interstellar medium in these galaxies are reviewed. A number of simple arguments about the physical state of the gas are given. Steady-state cooling flow models for these galaxies are presented, and their time-dependent evolution is discussed. The X-ray emission found in early-type galaxies indicates that they contain significant amounts of hot interstellar gas, and that they are not the gas-poor systems they were previously thought to be. In the brighter X-ray galaxies, the amounts of hot gas observed are consistent with those expected given the present rates of stellar mass loss. The required rates of heating of the gas are consistent with those expected from the motions of gas-losing stars and supernovae. The X-ray observations are generally more consistent with a lower rate of Type I supernovae than was previously thought.

The origins of cognitive dissonance: evidence from children and monkeys.

PubMed

Egan, Louisa C; Santos, Laurie R; Bloom, Paul

2007-11-01

In a study exploring the origins of cognitive dissonance, preschoolers and capuchins were given a choice between two equally preferred alternatives (two different stickers and two differently colored M&M's, respectively). On the basis of previous research with adults, this choice was thought to cause dissonance because it conflicted with subjects' belief that the two options were equally valuable. We therefore expected subjects to change their attitude toward the unchosen alternative, deeming it less valuable. We then presented subjects with a choice between the unchosen option and an option that was originally as attractive as both options in the first choice. Both groups preferred the novel over the unchosen option in this experimental condition, but not in a control condition in which they did not take part in the first decision. These results provide the first evidence of decision rationalization in children and nonhuman primates. They suggest that the mechanisms underlying cognitive-dissonance reduction in human adults may have originated both developmentally and evolutionarily earlier than previously thought.

A Duodenal Ulcer Caused by Pancreatic Ductal Hypertension with Chronic Pancreatitis.

PubMed

Imoto, Akira; Masuda, Daisuke; Okuda, Atsushi; Takagi, Wataru; Onda, Saori; Sano, Tatsushi; Mikami, Takashi; Mohamed, Malak; Ogura, Takeshi; Higuchi, Kazuhide

2015-01-01

We herein describe the case of a 67-year-old woman with a duodenal ulcer thought to be caused by elevated pancreatic ductal pressure. The patient complained of continuous upper abdominal pain. Her medical history included idiopathic chronic pancreatitis. Endoscopy revealed a huge duodenal ulcer located on the inferior duodenal angle, which had not been seen on endoscopic retrograde pancreatography two months previously. A combination study using endoscopy and contrast imaging confirmed the relationship between the duodenal ulcer and the pancreatic branch duct. To our knowledge, this is the first case of duodenal ulcer thought to be caused by elevated pancreatic ductal pressure.

Isolation of carbohydrate-metabolizing, extremely halophilic bacteria.

NASA Technical Reports Server (NTRS)

Tomlinson, G. A.; Hochstein, L. I.

1972-01-01

Four previously unrecognized strains of extremely halophilic bacteria that utilize carbohydrates have been isolated. Gas production proved an unreliable index of carbohydrate metabolism; therefore, carbohydrate utilization was measured by determining acid formation and sugar disappearance during growth. By these procedures, carbohydrate utilization was readily detected. The results suggest that carbohydrate dissimilation by extremely halophilic bacteria may be more common than previously thought and that the apparent rarity of carbohydrate-metabolizing halophiles may be an artifact of the isolation procedures used.

Opioid-use disorder among patients on long-term opioid therapy: impact of final DSM-5 diagnostic criteria on prevalence and correlates.

PubMed

Boscarino, Joseph A; Hoffman, Stuart N; Han, John J

2015-01-01

Previously, we estimated the prevalence and risk factors for prescription opioid-use disorder among outpatients on opioid therapy using the Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 and DSM-4 criteria. However, at the time, the DSM-5 criteria were not finalized. In the current study, we analyzed these data using the final DSM-5 criteria and compared these results. Using electronic records from a large US health care system, we identified outpatients receiving five or more prescription orders for opioid therapy in the past 12 months for noncancer pain (mean prescription orders =10.72; standard deviation =4.96). In 2008, we completed diagnostic interviews with 705 of these patients using the DSM-4 criteria. In the current study, we reassessed these results using the final DSM-5 criteria. The lifetime prevalence of DSM-5 opioid-use disorders using the final DSM-5 criteria was 58.7% for no or few symptoms (<2), 28.1% for mild symptoms (2-3), 9.7% for moderate symptoms (4-5), and 3.5% for severe symptoms (six or more). Thus, the lifetime prevalence of "any" prescription opioid-use disorder in this cohort was 41.3% (95% confidence interval [CI] =37.6-45.0). A comparison to the DSM-4 criteria indicated that the majority of patients with lifetime DSM-4 opioid dependence were now classified as having mild opioid-use disorder, based on the DSM-5 criteria (53.6%; 95% CI =44.1-62.8). In ordinal logistic regression predicting no/few, mild, moderate, and severe opioid-use disorder, the best predictors were age <65 years, current pain impairment, trouble sleeping, suicidal thoughts, anxiety disorders, illicit drug use, and history of substance abuse treatment. Given the final DSM-5 criteria, including the elimination of tolerance and withdrawal, inclusion of craving and abuse symptoms, and introduction of a new graded severity classification, the prevalence of opioid-use disorders has changed, while many of the DSM-4 risk factors for opioid dependence were similar. To our knowledge, this is one of the first studies to compare the final results for DSM-5 versus DSM-4 prescription opioid-use disorders among a high-risk patient population.

Opioid-use disorder among patients on long-term opioid therapy: impact of final DSM-5 diagnostic criteria on prevalence and correlates

PubMed Central

Boscarino, Joseph A; Hoffman, Stuart N; Han, John J

2015-01-01

Aims Previously, we estimated the prevalence and risk factors for prescription opioid-use disorder among outpatients on opioid therapy using the Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 and DSM-4 criteria. However, at the time, the DSM-5 criteria were not finalized. In the current study, we analyzed these data using the final DSM-5 criteria and compared these results. Methods Using electronic records from a large US health care system, we identified outpatients receiving five or more prescription orders for opioid therapy in the past 12 months for noncancer pain (mean prescription orders =10.72; standard deviation =4.96). In 2008, we completed diagnostic interviews with 705 of these patients using the DSM-4 criteria. In the current study, we reassessed these results using the final DSM-5 criteria. Results The lifetime prevalence of DSM-5 opioid-use disorders using the final DSM-5 criteria was 58.7% for no or few symptoms (<2), 28.1% for mild symptoms (2–3), 9.7% for moderate symptoms (4–5), and 3.5% for severe symptoms (six or more). Thus, the lifetime prevalence of “any” prescription opioid-use disorder in this cohort was 41.3% (95% confidence interval [CI] =37.6–45.0). A comparison to the DSM-4 criteria indicated that the majority of patients with lifetime DSM-4 opioid dependence were now classified as having mild opioid-use disorder, based on the DSM-5 criteria (53.6%; 95% CI =44.1–62.8). In ordinal logistic regression predicting no/few, mild, moderate, and severe opioid-use disorder, the best predictors were age <65 years, current pain impairment, trouble sleeping, suicidal thoughts, anxiety disorders, illicit drug use, and history of substance abuse treatment. Conclusion Given the final DSM-5 criteria, including the elimination of tolerance and withdrawal, inclusion of craving and abuse symptoms, and introduction of a new graded severity classification, the prevalence of opioid-use disorders has changed, while many of the DSM-4 risk factors for opioid dependence were similar. To our knowledge, this is one of the first studies to compare the final results for DSM-5 versus DSM-4 prescription opioid-use disorders among a high-risk patient population. PMID:26316838

Reduced activation in ventral striatum and ventral tegmental area during probabilistic decision-making in schizophrenia.

PubMed

Rausch, Franziska; Mier, Daniela; Eifler, Sarah; Esslinger, Christine; Schilling, Claudia; Schirmbeck, Frederike; Englisch, Susanne; Meyer-Lindenberg, Andreas; Kirsch, Peter; Zink, Mathias

2014-07-01

Patients with schizophrenia suffer from deficits in monitoring and controlling their own thoughts. Within these so-called metacognitive impairments, alterations in probabilistic reasoning might be one cognitive phenomenon disposing to delusions. However, so far little is known about alterations in associated brain functionality. A previously established task for functional magnetic resonance imaging (fMRI), which requires a probabilistic decision after a variable amount of stimuli, was applied to 23 schizophrenia patients and 28 healthy controls matched for age, gender and educational levels. We compared activation patterns during decision-making under conditions of certainty versus uncertainty and evaluated the process of final decision-making in ventral striatum (VS) and ventral tegmental area (VTA). We replicated a pre-described extended cortical activation pattern during probabilistic reasoning. During final decision-making, activations in several fronto- and parietocortical areas, as well as in VS and VTA became apparent. In both of these regions schizophrenia patients showed a significantly reduced activation. These results further define the network underlying probabilistic decision-making. The observed hypo-activation in regions commonly associated with dopaminergic neurotransmission fits into current concepts of disrupted prediction error signaling in schizophrenia and suggests functional links to reward anticipation. Forthcoming studies with patients at risk for psychosis and drug-naive first episode patients are necessary to elucidate the development of these findings over time and the interplay with associated clinical symptoms. Copyright © 2014 Elsevier B.V. All rights reserved.

Molecular structures of fructans from Agave tequilana Weber var. azul.

PubMed

Lopez, Mercedes G; Mancilla-Margalli, Norma A; Mendoza-Diaz, Guillermo

2003-12-31

Agave plants utilize crassulacean acid metabolism (CAM) for CO(2) fixation. Fructans are the principal photosynthetic products generated by agave plants. These carbohydrates are fructose-bound polymers frequently with a single glucose moiety. Agave tequilana Weber var. azul is an economically important CAM species not only because it is the sole plant allowed for tequila production but because it is a potential source of prebiotics. Because of the large amounts of carbohydrates in A. tequilana, in this study the molecular structures of its fructans were determined by fructan derivatization for linkage analysis coupled with gas chromatography-mass spectrometry (GC-MS), nuclear magnetic resonance (NMR), and matrix-assisted laser desorption time-of-flight mass spectrometry (MALDI-TOF-MS). Fructans were extracted from 8-year-old A. tequilana plants. The linkage types present in fructans from A. tequilana were determined by permethylation followed by reductive cleavage, acetylation, and finally GC-MS analysis. Analysis of the degree of polymerization (DP) estimated by (1)H NMR integration and (13)C NMR and confirmed by MALDI-TOF-MS showed a wide DP ranging from 3 to 29 units. All of the analyses performed demonstrated that fructans from A. tequilana consist of a complex mixture of fructooligosaccharides containing principally beta(2 --> 1) linkages, but also beta(2 --> 6) and branch moieties were observed. Finally, it can be stated that fructans from A. tequilana Weber var. azul are not an inulin type as previously thought.

Distribution and abundance of cetaceans in the north-central and western Gulf of Mexico. Final report. Volume 3. Appendix C. Part 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, R.W.; Fargion, G.S.

1996-05-24

The purpose of the study was to determine the distribution and abundance of cetaceans in areas potentially affected by future oil and gas activities along the continental slope of the north-central and western Gulf of Mexico. This 3.75 year project commenced 1 October 1991 and finished 15 July 1995. The study area was bounded by the Florida-Alabama border, the Texas-Mexico border, and the 100 m and 2,000 m isobaths. Cetacean distribution and abundance were determined from seasonal aerial and shipboard visual surveys and shipboard acoustic surveys. In addition, hydrographic data were collected in situ and by satellite remote sensing tomore » characterize cetacean habitat. Finally, tagging and tracking of sperm whales using satellite telemetry was attempted. Appendix C Part 2 contains the hydrogrpahic data collected during TIO Cruises 5-7. Cetaceans were observed throughout the study area during all four seasons. Nineteen species were identified, including two species (melon-headed whales and Fraser`s dolphins) previously thought to be rare in the Gulf. Pantropical spotted dolphins, bottlenose dolphins, clymene dolphins, striped dolphins, Atlantic spotted dolphins, and melon-headed whales were the most common small cetaceans and the sperm whale was the most common large cetacean. The mean annual abundance for all cetaceans was estimated to be 19,198. Although the study area had complex and dynamic oceanography, bottom depth was the only environmental variable which correlated to cetacean distribution.« less

Distribution and abundance of cetaceans in the north-central and western Gulf of Mexico. Final report. Volume 1. Executive summary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, R.W.; Fargion, G.S.

1996-05-24

The purpose of the study was to determine the distribution and abundance of cetaceans in areas potentially affected by future oil and gas activities along the continental slope of the north-central and western Gulf of Mexico. This 3.75 year project commenced 1 October 1991 and finished 15 July 1995. The study area was bounded by the Florida-Alabama border, the Texas-Mexico border, and the 100 m and 2,000 m isobaths. Cetacean distribution and abundance were determined from seasonal aerial and shipboard visual surveys and shipboard acoustic surveys. In addition, hydrographic data were collected in situ and by satellite remote sensing tomore » characterize cetacean habitat. Finally, tagging and tracking of sperm whales using satellite telemetry was attempted. This volume summarizes the results of the study. Cetaceans were observed throughout the study area during all four seasons. Nineteen species were identified, including two species (melon-headed whales and Fraser`s dolphins) previously thought to be rare in the Gulf. Pantropical spotted dolphins, bottlenose dolphins, clymene dolphins, striped dolphins, Atlantic spotted dolphins, and melon-headed whales were the most common small cetaceans and the sperm whale was the most common large cetacean. The mean annual abundance for all cetaceans was estimated to be 19,198. Although the study area had complex and dynamic oceanography, bottom depth was the only environmental variable which correlated to cetacean distribution.« less

Distribution and abundance of cetaceans in the north-central and western Gulf of Mexico. Final report. Volume 3. Appendix B

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1996-05-24

The purpose of the study was to determine the distribution and abundance of cetaceans in areas potentially affected by future oil and gas activities along the continental slope of the north-central and western Gulf of Mexico. This 3.75 year project commenced 1 October 1991 and finished 15 July 1995. The study area was bounded by the Florida-Alabama border, the Texas-Mexico border, and the 100 m and 2,000 m isobaths. Cetacean distribution and abundance were determined from seasonal aerial and shipboard visual surveys and shipboard acoustic surveys. In addition, hydrographic data were collected in situ and by satellite remote sensing tomore » characterize cetacean habitat. Finally, tagging and tracking of sperm whales using satellite telemetry was attempted. Appendix B contains the hydrographic data collected during all four NMFS-SEFSC cruises. Cetaceans were observed throughout the study area during all four seasons. Nineteen species were identified, including two species (melon-headed whales and Fraser`s dolphins) previously thought to be rare in the Gulf. Pantropical spotted dolphins, bottlenose dolphins, clymene dolphins, striped dolphins, Atlantic spotted dolphins, and melon-headed whales were the most common small cetaceans and the sperm whale was the most common large cetacean. The mean annual abundance for all cetaceans was estimated to be 19,198. Although the study area had complex and dynamic oceanography, bottom depth was the only environmental variable which correlated to cetacean distribution.« less

Distribution and abundance of cetaceans in the north-central and western Gulf of Mexico. Final report. Volume 2. Technical report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, R.W.; Fargion, G.S.

1996-05-24

The purpose of the study was to determine the distribution and abundance of cetaceans in areas potentially affected by future oil and gas activities along the continental slope of the north-central and western Gulf of Mexico. This 3.75 year project commenced 1 October 1991 and finished 15 July 1995. The study area was bounded by the Florida-Alabama border, the Texas-Mexico border, and the 100 m and 2,000 m isobaths. Cetacean distribution and abundance were determined from seasonal aerial and shipboard visual surveys and shipboard acoustic surveys. In addition, hydrographic data were collected in situ and by satellite remote sensing tomore » characterize cetacean habitat. Finally, tagging and tracking of sperm whales using satellite telemetry was attempted. This volume summarizes the results of the study. Cetaceans were observed throughout the study area during all four seasons. Nineteen species were identified, including two species (melon-headed whales and Fraser`s dolphins) previously thought to be rare in the Gulf. Pantropical spotted dolphins, bottlenose dolphins, clymene dolphins, striped dolphins, Atlantic spotted dolphins, and melon-headed whales were the most common small cetaceans and the sperm whale was the most common large cetacean. The mean annual abundance for all cetaceans was estimated to be 19,198. Although the study area had complex and dynamic oceanography, bottom depth was the only environmental variable which correlated to cetacean distribution.« less

Distribution and abundance of cetaceans in the north-central and western Gulf of Mexico. Final report. Volume 3. Appendix C. Part 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, R.W.; Fargion, G.S.

1996-05-24

The purpose of the study was to determine the distribution and abundance of cetaceans in areas potentially affected by future oil and gas activities along the continental slope of the north-central and western Gulf of Mexico. This 3.75 year project commenced 1 October 1991 and finished 15 July 1995. The study area was bounded by the Florida-Alabama border, the Texas-Mexico border, and the 100 m and 2,000 m isobaths. Cetacean distribution and abundance were determined from seasonal aerial and shipboard visual surveys and shipboard acoustic surveys. In addition, hydrographic data were collected in situ and by satellite remote sensing tomore » characterize cetacean habitat. Finally, tagging and tracking of sperm whales using satellite telemetry was attempted. Appendix C Part 1 contains the hydrographic data collected during TIO Cruises 1-4. Cetaceans were observed throughout the study area during all four seasons. Nineteen species were identified, including two species (melon-headed whales and Fraser`s dolphins) previously thought to be rare in the Gulf. Pantropical spotted dolphins, bottlenose dolphins, clymene dolphins, striped dolphins, Atlantic spotted dolphins, and melon-headed whales were the most common small cetaceans and the sperm whale was the most common large cetacean. The mean annual abundance for all cetaceans was estimated to be 19,198. Although the study area had complex and dynamic oceanography, bottom depth was the only environmental variable which correlated to cetacean distribution.« less

Perceptions, use and attitudes of pharmacy customers on complementary medicines and pharmacy practice

PubMed Central

2010-01-01

Background Complementary medicines (CMs) are popular amongst Australians and community pharmacy is a major supplier of these products. This study explores pharmacy customer use, attitudes and perceptions of complementary medicines, and their expectations of pharmacists as they relate to these products. Methods Pharmacy customers randomly selected from sixty large and small, metropolitan and rural pharmacies in three Australian states completed an anonymous, self administered questionnaire that had been pre-tested and validated. Results 1,121 customers participated (response rate 62%). 72% had used CMs within the previous 12 months, 61% used prescription medicines daily and 43% had used both concomitantly. Multivitamins, fish oils, vitamin C, glucosamine and probiotics were the five most popular CMs. 72% of people using CMs rated their products as 'very effective' or 'effective enough'. CMs were as frequently used by customers aged 60 years or older as younger customers (69% vs. 72%) although the pattern of use shifted with older age. Most customers (92%) thought pharmacists should provide safety information about CMs, 90% thought they should routinely check for interactions, 87% thought they should recommend effective CMs, 78% thought CMs should be recorded in customer's medication profile and 58% thought pharmacies stocking CMs should also employ a complementary medicine practitioner. Of those using CMs, 93% thought it important for pharmacists to be knowledgeable about CMs and 48% felt their pharmacist provides useful information about CMs. Conclusions CMs are widely used by pharmacy customers of all ages who want pharmacists to be more involved in providing advice about these products. PMID:20646290

Dysfunctional Metacognitive Beliefs in Body Dysmorphic Disorder

PubMed Central

Zeinodini, Zahra; Sedighi, Sahar; Rahimi, Mandana Baghertork; Noorbakhsh, Simasadat; Esfahani, Sepideh Rajezi

2016-01-01

The present study aims to examine the correlation of body dysmorphic disorder, with metacognitive subscales, metaworry and thought-fusion. The study was conducted in a correlation framework. Sample included 155 high school students in Isfahan, Iran in 2013-2014, gathered through convenience sampling. To gather data about BDD, Yale-Brown Obsessive Compulsive Scale Modified for BDD was applied. Then, Meta Cognitive Questionnaire, Metaworry Questionnaire, and Thought-Fusion Inventory were used to assess metacognitive subscales, metaworry and thought-fusion. Data obtained from this study were analyzed using Pearson correlation and multiple regressions in SPSS 18. Result indicated YBOCS-BDD scores had a significant correlation with scores from MCQ (P<0.05), MWG (P<0.05), and TFI (P<0.05). Also, multiple regressions were run to predict YBOCS from TFI, MWQ, and MCQ-30. These variables significantly predicted YBOCS [F (3,151) =32.393, R2=0.57]. Findings indicated that body dysmorphic disorder was significantly related to metacognitive subscales, metaworry, and thought fusion in high school students in Isfahan, which is in line with previous studies. A deeper understanding of these processes can broaden theory and treatment of BDD, thereby improve the lives of sufferers and potentially protect others from developing this devastating disorder. PMID:26493420

Expert views on societal responses to different applications of nanotechnology: a comparative analysis of experts in countries with different economic and regulatory environments

NASA Astrophysics Data System (ADS)

Gupta, Nidhi; Fischer, Arnout R. H.; George, Saji; Frewer, Lynn J.

2013-08-01

The introduction of different applications of nanotechnology will be informed by expert views regarding which (types of) application will be most societally acceptable. Previous research in Northern Europe has indicated that experts believe that various factors will be influential, predominant among these being public perceptions of benefit, need and consumer concern about contact with nanomaterials. These factors are thought by experts to differentiate societal acceptance and rejection of nanotechnology applications. This research utilises a larger sample of experts ( N = 67) drawn from Northern America, Europe, Australasia, India and Singapore to examine differences in expert opinion regarding societal acceptance of different applications of nanotechnology within different technological environments, consumer cultures and regulatory regimes. Perceived risk and consumer concerns regarding contact with nano-particles are thought by all experts to drive rejection, and perceived benefits to influence acceptance, independent of country. Encapsulation and delivery of nutrients in food was thought to be the most likely to raise societal concerns, while targeted drug delivery was thought most likely to be accepted. Lack of differentiation between countries suggests that expert views regarding social acceptance may be homogenous, independent of local contextual factors.

The dynamic nature of cognition during wayfinding

PubMed Central

Spiers, Hugo J.; Maguire, Eleanor A.

2008-01-01

Much of our day-to-day wayfinding behaviour takes place in familiar large-scale urban environments, yet there is a dearth of studies examining how wayfinding unfolds on a second-by-second basis in this context. Here we used a retrospective verbal report protocol, eye tracking and a highly accurate virtual reality simulation of a real city (London, UK) to examine this issue. Subjects, who were taxi drivers, were able to produce extremely detailed accounts of what they had been thinking during wayfinding, which were validated by independent eye-tracking data. There was a high degree of consistency in the types of thoughts across subjects, permitting classification into a number of distinct categories. Moreover, it was possible to quantify the number of thoughts in each category, their durations and temporal order. Detailed analysis of the verbal reports provided new insights into the processes and strategies involved, and highlighted a greater range of thoughts than has previously been reported in studies of wayfinding. By analysing the temporal order of thoughts it was possible to identify specific relationships between categories. Some of these relationships were predicted by current cognitive models of wayfinding, others were novel, thus shedding new light on how navigation unfolds in a busy city. PMID:19325934

Cognitive aspects of sexual functioning: differences between East Asian-Canadian and Euro-Canadian women.

PubMed

Morton, Heather; Gorzalka, Boris B

2013-11-01

The purpose of this study was to investigate the sexual beliefs of female undergraduates, as well as the thoughts they experience during sexual experiences. The study aimed to determine potential differences in these variables between East Asian-Canadians and Euro-Canadians, as well as the influence of acculturation on these variables. In addition, the relationships between sexual beliefs, automatic thoughts, and specific aspects of sexual functioning were examined. Euro-Canadian (n = 77) and East Asian-Canadian (n = 123) undergraduate women completed the Sexual Dysfunctional Beliefs Questionnaire, the Sexual Modes Questionnaire, the Female Sexual Function Index, and the Vancouver Index of Acculturation. East Asian women endorsed almost all sexual beliefs assessed in this study more than did Euro-Canadian women, and endorsement of these beliefs was associated with acculturation. In addition, East Asian-Canadian and Euro-Canadian women differed in the frequency of experiencing negative automatic thoughts. Results also revealed associations between difficulties in sexual functioning, and both sexual beliefs and automatic thoughts. Together, these results provide preliminary support for the hypothesis that differences in cognitive aspects of sexuality may underlie the differences in sexual functioning previously observed between these two groups.

The U.S.-Canada Border Effect : Smaller Than Previously Thought and Becoming Smaller

DOT National Transportation Integrated Search

2012-05-30

We revisit the effect of the U.S.-Canada national border on trade, considering to what extent the border reduces trade when : observable economic factors are controlled. A reexamination of the data yields estimates of the border effect that are 50% :...

ROUTE-DEPENDENT EFFECTS OF TOLUENE ON SIGNAL DETECTION BEHAVIOR IN RATS.

EPA Science Inventory

The acute effects of toluene and other solvents on behavior are thought to depend upon their concentration in the brain. We have shown previously that inhaled toluene and trichloroethylene disrupt sustained attention in rats as assessed with a visual signal detection task (SDT). ...

Genetic diversity of Toxoplama gondii isolates from Ethiopian feral cats

USDA-ARS?s Scientific Manuscript database

Recent studies indicate greater genetic variability among isolates of Toxoplasma gondii worldwide than previously thought. However, there is no information on genetic diversity of T. gondii from any host in Ethiopia. In the present study, genotyping was performed on viable T. gondii isolates by bioa...

Mathematics in the Age of Jane Austen: Essential Skills of 1800.

ERIC Educational Resources Information Center

Gray, S. I. B.

2000-01-01

Discusses textbooks from the 1800s for young ladies versus young men, for the youngest students, more advanced students, and university students. Regards these publications as furnishing a record of the skills thought to be essential at the turn of the previous century. (KHR)

Thinking Inside the Box

ERIC Educational Resources Information Center

Golding, Barry

2011-01-01

The "men's sheds" movement is a grassroots phenomenon that has engaged and inspired men from communities across Australia in hands-on, workshop-based social activity. This article seeks to "unwrap" one of several forms of learning that have been found to be enthusiastically embraced by older men previously thought of, almost…

A Signal Detection Theory Analysis of Behavioral Pattern Separation Paradigms

ERIC Educational Resources Information Center

Loiotile, Rita E.; Courtney, Susan M.

2015-01-01

Behavioral pattern separation (BPS) paradigms ask participants to discriminate previously encoded (old) stimuli from highly similar (lure) and categorically distinct (novel) stimuli. The lure-old discrimination, thought to uniquely reflect pattern separation in the hippocampal formation, is typically pitted against the traditional novel-old…

College Students' Reasons for Concealing Suicidal Ideation

ERIC Educational Resources Information Center

Burton Denmark, Adryon; Hess, Elaine; Becker, Martin Swanbrow

2012-01-01

Self-reported reasons for concealing suicidal ideation were explored using data from a national survey of undergraduate and graduate students: 558 students indicated that they seriously considered attempting suicide during the previous year and did not tell anyone about their suicidal thoughts. Content analysis of students' qualitative responses…

Planning Perspectives for Education.

ERIC Educational Resources Information Center

Johnston, A. P., Ed.; McNamara, James F., Ed.

This book presents a collection of previously published journal articles dealing with the theory, practice, and research of planning. The various readings were selected to stimulate thought and action in educational planning, rather than to present solutions to specific problems. The articles include "Knowledge and Action: A Guide to Planning…

Seizure Disorders: An Alternative Explanation for Students' Inattention.

ERIC Educational Resources Information Center

Agnew, Christina M.; Nystul, Michael S.; Conner, Mary Catherine

1998-01-01

Provides an overview of seizure disorders. They are more common than previously thought, and most have their onset in adolescence. Types of seizure disorders common in children, their symptoms, and treatment are described. A case example illustrates behavior in school and a paradoxical medication effect. (EMK)

The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach.

PubMed

Harduin-Lepers, Anne; Mollicone, Rosella; Delannoy, Philippe; Oriol, Rafael

2005-08-01

The animal sialyltransferases are Golgi type II transmembrane glycosyltransferases. Twenty distinct sialyltransferases have been identified in both human and murine genomes. These enzymes catalyze transfer of sialic acid from CMP-Neu5Ac to the glycan moiety of glycoconjugates. Despite low overall identities, they share four conserved peptide motifs [L (large), S (small), motif III, and motif VS (very small)] that are hallmarks for sialyltransferase identification. We have identified 155 new putative genes in 25 animal species, and we have exploited two lines of evidence: (1) sequence comparisons and (2) exon-intron organization of the genes. An ortholog to the ancestor present before the split of ST6Gal I and II subfamilies was detected in arthropods. An ortholog to the ancestor present before the split of ST6GalNAc III, IV, V, and VI subfamilies was detected in sea urchin. An ortholog to the ancestor present before the split of ST3Gal I and II subfamilies was detected in ciona, and an ortholog to the ancestor of all the ST8Sia was detected in amphioxus. Therefore, single examples of the four families (ST3Gal, ST6Gal, ST6GalNAc, and ST8Sia) have appeared in invertebrates, earlier than previously thought, whereas the four families were all detected in bony fishes, amphibians, birds, and mammals. As previously hypothesized, sequence similarities among sialyltransferases suggest a common genetic origin, by successive duplications of an ancestral gene, followed by divergent evolution. Finally, we propose predictions on these invertebrates sialyltransferase-related activities that have not previously been demonstrated and that will ultimately need to be substantiated by protein expression and enzymatic activity assays.

Toward an understanding of disequilibrium dihedral angles in mafic rocks

USGS Publications Warehouse

Holness, Marian B.; Humphreys, Madeleine C.S.; Sides, Rachel; Helz, Rosalind T.; Tegner, Christian

2012-01-01

The median dihedral angle at clinopyroxene-plagioclase-plagioclase junctions in mafic rocks, Θcpp, is generally lower than equilibrium (109˚ {plus minus} 2˚). Observation of a wide range of mafic bodies demonstrates that previous work on systematic variations of Θcpp is incorrect in several important respects. Firstly, the spatial distribution of plagioclase compositional zoning demonstrates that the final geometry of three-grain junctions, and hence Θcpp, is formed during solidification (the igneous process): sub-solidus textural modification in most dolerites and gabbros, previously thought to be the dominant control on Θcpp, is insignificant. Θcpp is governed by mass transport constraints, the inhibiting effects of small pore size on crystallization, and variation in relative growth rates of pyroxene and plagioclase. During rapid cooling, pyroxene preferentially fills wider pores while the narrower pores remain melt-filled, resulting in an initial value of Θcpp of 78˚, rather than 60˚ which would be expected if all melt-filled pores were filled with pyroxene. Lower cooling rates create a higher initial Θcpp due to changes in relative growth rates of the two minerals at the nascent three-grain junction. Low Θcpp (associated with cuspate clinopyroxene grains at triple junctions) can also be diagnostic of infiltration of previously melt-free rocks by late-stage evolved liquids (the metasomatic process). Modification of Θcpp by sub-solidus textural equilibration (the metamorphic process) is only important for fine-grained mafic rocks such as chilled margins and intra-plutonic chill zones. In coarse-grained gabbros from shallow crustal intrusions the metamorphic process occurs only in the centres of oikocrysts, associated with rounding of chadacrysts.

A Grammatico-Semantic Exploration of the Problems of Sentence Formation and Interpretation in the Classroom, Volume 1. Final Report.

ERIC Educational Resources Information Center

Bateman, Donald R.; Zidonis, Frank J.

In the introduction to this volume of a two volume document (See also TE 002 131.) written for curriculum developers, Donald Bateman identifies the recent periods in the development of linguistic thought and methodology, and presents language curriculum development as the continuing exploration of the processes of evolving linguistic structures.…

Reproducing Advantage: The Perspective of English School Leavers on Studying Abroad

ERIC Educational Resources Information Center

King, Russell; Findlay, Allan; Ahrens, Jill; Dunne, Mairead

2011-01-01

This paper presents results of a questionnaire survey of 1400 Year 13 (final-year) school and sixth-form pupils in two contrasting areas of England, which asked them about their thoughts and plans to study at university abroad. Key questions that the survey sought to answer were the following. How many and what proportion of all higher education…

The Effect of Alternative Career Decision-Making Strategies on the Quality of Resulting Decisions. Final Report.

ERIC Educational Resources Information Center

Krumboltz, John D.; And Others

A project studied whether methods used to make career decisions affect their outcomes. Part A describes the correlational study to discover how thoughts and actions of community college students related to their satisfaction with outcomes of their decisions. It focuses on the administration to 255 community college students of a Decision-Making…

Special Relativity in Week One: 4) Lack of Simultaneity

ERIC Educational Resources Information Center

Huggins, Elisha

2011-01-01

This is our final article on teaching special relativity in the first week of an introductory physics course. One of the profound changes in our view of the world was Einstein's discovery of the lack of simultaneity. He illustrated this result with a thought experiment in which we observe a railroad car passing by us. We see the two ends of the…

Children and Young People of Kent: Survey 2006/7. Final Report

ERIC Educational Resources Information Center

Chamberlain, Tamsin; Easton, Claire; Morris, Marian; Riggall, Anna

2007-01-01

The National Foundation for Educational Research (NFER) was commissioned by Kent County Council (KCC) to conduct an independent survey of children and young people in Kent. The council and its partner agencies wanted to find out what children and young people thought about a range of issues related to the five Every Child Matters (ECM) outcomes.…

Darwin's place in the history of thought: A reevaluation

PubMed Central

Richards, Robert J.

2009-01-01

Scholars have usually given Darwin's theory a neo-Darwinian interpretation. A more careful examination of the language of Darwin's notebooks and the language of the Origin of Species indicates that he reconstructed nature with a definite purpose: the final goal of man as a moral creature. In the aftermath of the Origin, Darwin, however, became more circumspect. PMID:19528661

Persistence of Memory for Ignored Lists of Digits: Areas of Developmental Constancy and Change.

ERIC Educational Resources Information Center

Cowan, Nelson; Nugent, Lara D.; Elliott, Emily M.; Saults, J. Scott

2000-01-01

Examined persistence of sensory memory by studying developmental differences in recall of attended and ignored lists of digits for second-graders, fifth-graders, and adults. Found developmental increase in the persistence of memory only for the final item in an ignored list, which is the item for which sensory memory is thought to be the most…

The Emergence of a Content Acceptance Model (CAM): New Thoughts Regarding the Trial, Adoption, and Usage of New Media

DTIC Science & Technology

2009-03-26

child vi Acknowledgments I took on this thesis as a challenge to myself for two reasons. First, I wanted to complete a thesis outside my...first child . I also need to think all my previous Wing Commander, Air Force squadron commanders, previous teachers, and other Air Force leaders...their mind 18: Phishers, spammers, and porn agencies send out messages trying to make money 17: To stay connected with family/friends all over nation

Age-related differences in mind-wandering in daily life.

PubMed

Maillet, David; Beaty, Roger E; Jordano, Megan L; Touron, Dayna R; Adnan, Areeba; Silvia, Paul J; Kwapil, Thomas R; Turner, Gary R; Spreng, R Nathan; Kane, Michael J

2018-06-01

In recent years, several laboratory studies have indicated that healthy older adults exhibit a reduction in mind-wandering frequency compared with young adults. However, it is unclear if these findings extend to daily life settings. In the current study, using experience sampling over the course of a week in the daily life of 31 young and 20 older adults, we assessed age-related differences in: (a) mind-wandering frequency, (b) the relationship between affect and mind-wandering frequency, and (c) content of mind wandering. Older adults mind wandered less than young adults in daily life. Across age groups, negative affect was positively associated with mind-wandering occurrence. Finally, older adults reported that their thoughts were more pleasant, interesting, and clear compared with young adults, who had thoughts that were more dreamlike, novel, strange, and racing. Our results provide the first demonstration using thought sampling that older adults exhibit a reduction in mind-wandering frequency in daily life. Implications for current theories of age-related reductions in mind-wandering frequency are discussed. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Cutoff Scores for the Autism Spectrum Disorder--Comorbid for Children (ASD-CC)

ERIC Educational Resources Information Center

Thorson, Ryan T.; Matson, Johnny L.

2012-01-01

Once considered rare, Autism Spectrum Disorders (ASD) are increasingly becoming viewed as common disorders. Additionally, recent studies suggest that comorbid psychopathology within ASD is more common than previously thought. Though these deficits exist, specific instruments to diagnose psychopathology in this population are not available. In this…

Aneides ferreus (clouded salamander): arboreal activity

Treesearch

William W. Price; Clinton P. Landon; Eric D. Forsman

2010-01-01

Aneides ferreus (clouded salamander) inhabits the forests of western Oregon and extreme northwestern California. Although thought to be primarily terrestrial, A. ferreus has occasionally been found as high as 60 m up in trees and two recent reports suggest that it may be more arboreal than previously believed. However, it is...

EXTRACELLULAR ENZYME ACTIIVTY AS A SURROGATE FOR NUTRIENTS AND NUTRIENT HISTORY IN GREAT LAKES WETLANDS

EPA Science Inventory

Great Lakes ecosystems are generally thought to be P-limited, but N-limitation may be more common than previously suspected. N-limitation should be most obvious in freshwater coastal wetlands, where the anaerobic oxidation of organic carbon may be limited by nitrate availability...

Berry fruit differentially improves age-related decrements in behavior based on baseline status

USDA-ARS?s Scientific Manuscript database

Aging and neurodegenerative diseases are thought to be the results of prolonged effects of oxidative stress and inflammation. Previously, we have shown that daily supplementation of berry fruits, such as blueberry or raspberry, was able to reverse age-related deficits in behavioral and neuronal func...

Effects of a school-based intensive intervention on systemic inflammation and disease risk in Mexican-American children

USDA-ARS?s Scientific Manuscript database

Childhood obesity is associated with an increased risk for cardiovascular disease and type 2 Diabetes mellitus. Systemic inflammation is thought to mediate this relationship. We have previously demonstrated that an intervention designed specifically for Mexican-American children that incorporates bo...

Evolution: oskar reveals missing link in co-optive evolution.

PubMed

Abouheif, Ehab

2013-01-07

The oskar gene is critical for germ plasm formation and reproduction in higher insects. A recent study reports that oskar has more ancient roots than previously thought, indicating it was co-opted for its reproductive role in higher insects. Copyright © 2013 Elsevier Ltd. All rights reserved.

Effects of Adolescent Sociocognitive Development on the Cortisol Response to Social Evaluation

ERIC Educational Resources Information Center

van den Bos, Esther; van Duijvenvoorde, Anna C. K.; Westenberg, P. Michiel

2016-01-01

Adolescents become increasingly sensitive to social evaluation. Some previous studies have related this change to pubertal development. The present longitudinal study examined the role of sociocognitive development. We investigated whether or not the transition to recursive thinking, the ability to think about (others') thoughts, would be…

International Perspectives on Inclusion: Concluding Thoughts.

ERIC Educational Resources Information Center

Timmons, Vianne

2002-01-01

This article discusses overall trends and commonalities among previous articles on inclusion in the United Kingdom, Ireland, India, South Africa, Canada, New Zealand, and Australia. It concludes that inclusive education must be viewed in a broader context that looks at school reform and the societal context. Teacher education is stressed.…

Contextual Modulation of Mirror and Countermirror Sensorimotor Associations

ERIC Educational Resources Information Center

Cook, Richard; Dickinson, Anthony; Heyes, Cecilia

2012-01-01

Automatic imitation--the unintended copying of observed actions--is thought to be a behavioral product of the mirror neuron system (MNS). Evidence that the MNS develops through associative learning comes from previous research showing that automatic imitation is attenuated by countermirror training, in which the observation of one action is paired…

A Cognitive Behavioural Group Approach for Adolescents with Disruptive Behaviour in Schools

ERIC Educational Resources Information Center

Ruttledge, Richard A.; Petrides, K. V.

2012-01-01

Cognitive behavioural approaches emphasize the links between thoughts, feelings and behaviour (Greig, 2007). Previous research has indicated that these approaches are efficacious in reducing disruptive behaviour in adolescents. The aim of the current study was to provide further evaluation of cognitive behavioural group work to reduce disruptive…

Behavioral Ecology of Subterranean Termites and Implications for Control

Treesearch

J. Kenneth Grace

1991-01-01

Subterranean termites are important structural pests in much of North America, and worldwide. Recent studies of eastern subterranean termite (Reticulitermes flavipes [Kollar]) colonies in Ontario, Canada, indicate that these colonies contain greater foraging populations and forage over larger territories than was previously thought to be the case....

Constructivism in the Classroom: Epistemology, History, and Empirical Evidence

ERIC Educational Resources Information Center

Matthews, William J.

2003-01-01

Over the previous two decades the emergence of post-modernist thought (i.e., radical constructivism, social constructivism, deconstructivism, post-structuralism, and the like) on the American intellectual landscape has presented a number of challenges to various fields of intellectual endeavor (i.e., literature, natural science, and social…

GLUTATHIONE (GSH) CONCENTRATIONS VARY WITH THE CELL CYCLE IN MATURING HAMSTER OOCYTES, ZYGOTES AND PRE-IMPLANATION EMBRYOS

EPA Science Inventory

Abstract
Glutathione (GSH) is thought to play critical roles in oocyte function including spindle maintenance and provision of reducing power needed to initiate sperm chromatin decondensation. Previous observations that GSH concentrations are higher in mature than immature o...

Building a better Faraday cage

NASA Astrophysics Data System (ADS)

MartinAlfven; Wright, David; skocpol; Rounce, Graham; Richfield, Jon; W, Nick; wheelsonfire

2015-11-01

In reply to the physicsworld.com news article “Are Faraday cages less effective than previously thought?” (15 September, http://ow.ly/SfklO), about a study that indicated, based on mathematical modelling, that conducting wire-mesh cages may not be as good at excluding electromagnetic radiation as is commonly assumed.

Blueberries affect neuroinflammation and cognition differentially depending on individual cognitive baseline status

USDA-ARS?s Scientific Manuscript database

Aging and neurodegenerative diseases are thought to be the results of prolonged effects of oxidative stress and inflammation. Previously, we have shown that daily supplementation of blueberries (BBs) was able to reverse age-related deficits in behavioral and neuronal function in aged rats. However, ...

Differential effects of blueberry polyphenols on age-associated neuroinflammation and cognition

USDA-ARS?s Scientific Manuscript database

Long-term effects of oxidative stress and inflammatory insults are thought to contribute to the decrements in cognitive performance seen in aging and neurodegenerative diseases. In previous studies, we have shown the beneficial effects of various dark-colored berry fruits in reversing age-related de...

The numerology of T cell functional diversity.

PubMed

Haining, W Nicholas

2012-01-27

Memory T cells are heterogeneous in phenotype and function. In this issue of Immunity, Newell et al. (2012) use a new flow cytometry platform to show that the functional heterogeneity of the human T cell compartment is even greater than previously thought. Copyright © 2012 Elsevier Inc. All rights reserved.

Students' Ideas about Plants and Plant Growth

ERIC Educational Resources Information Center

Barman, Charles R.; Stein, Mary; McNair, Shannan; Barman, Natalie S.

2006-01-01

Because the National Science Education Standards (1996) outline specific things K-8 students should know about plants, and previous data indicated that elementary students had difficulty understanding some major ideas about plants and plant growth, the authors of this article thought it appropriate to initiate an investigation to determine the…

Perfecting Language: Experimenting with Vocabulary Learning

ERIC Educational Resources Information Center

Absalom, Matthew

2014-01-01

One of the thorniest aspects of teaching languages is developing students' vocabulary, yet it is impossible to be "an accurate and highly communicative language user with a very small vocabulary" (Milton, 2009, p. 3). Nation (2006) indicates that more vocabulary than previously thought is required to function well both at spoken and…

Establishing an Explanatory Model for Mathematics Identity

ERIC Educational Resources Information Center

Cribbs, Jennifer D.; Hazari, Zahra; Sonnert, Gerhard; Sadler, Philip M.

2015-01-01

This article empirically tests a previously developed theoretical framework for mathematics identity based on students' beliefs. The study employs data from more than 9,000 college calculus students across the United States to build a robust structural equation model. While it is generally thought that students' beliefs about their own competence…

Effects of dietary blueberry on cognition and in vivo and in vitro inflammatory status

USDA-ARS?s Scientific Manuscript database

Chronic inflammation is thought to play a role in age-related cognitive decline. Previous studies from our laboratory have shown that dietary intervention with darkly pigmented berry fruit can reduce systemic and central biomarkers of inflammation while reversing behavioral impairments in aged rats....

Evaluating Conceptual Metaphor Theory

ERIC Educational Resources Information Center

Gibbs, Raymond W., Jr.

2011-01-01

A major revolution in the study of metaphor occurred 30 years ago with the introduction of "conceptual metaphor theory" (CMT). Unlike previous theories of metaphor and metaphorical meaning, CMT proposed that metaphor is not just an aspect of language, but a fundamental part of human thought. Indeed, most metaphorical language arises from…

Effect of abomasal butyrate infusion on gene expression in the duodenum of lambs

USDA-ARS?s Scientific Manuscript database

A previous study infusing butyrate into the abomasum of sheep produced increased oxygen, glucose, glutamate, and glutamine uptake by the portal-drained viscera. These changes were thought to be partially due to increases in glycolysis and cell proliferation. The purpose of this study was to evaluate...

Assessing Quality of Critical Thought in Online Discussion

ERIC Educational Resources Information Center

Weltzer-Ward, Lisa; Baltes, Beate; Lynn, Laura Knight

2009-01-01

Purpose: The purpose of this paper is to describe a theoretically based coding framework for an integrated analysis and assessment of critical thinking in online discussion. Design/methodology/approach: The critical thinking assessment framework (TAF) is developed through review of theory and previous research, verified by comparing results to…

Teaching African American Learners to Read: Perspectives and Practices

ERIC Educational Resources Information Center

Hammond, Bill, Ed.; Hoover, Mary Eleanor Rhodes, Ed.; McPhail, Irving Pressley, Ed.

2005-01-01

This collection of original and previously published articles fills a critical need for professional literature that documents successful research-based practices and programs that teach African American children to read. Thoughtful commentary on historic and current issues, discussion of research-based best practices, and examples of culturally…

Radiation effect on implanted pacemakers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pourhamidi, A.H.

1983-10-01

It was previously thought that diagnostic or therapeutic ionizing radiation did not have an adverse effect on the function of cardiac pacemakers. Recently, however, some authors have reported damaging effect of therapeutic radiation on cardiac pulse generators. An analysis of a recently-extracted pacemaker documented the effect of radiation on the pacemaker pulse generator.

"Doch ein Begriff muss bei dem Worte sein": Some Thoughts on Electronically Annotated Literary Texts.

ERIC Educational Resources Information Center

Duncan, Bruce; Foelsche, Otmar K. E.

1995-01-01

Discusses the use of electronic glossaries, annotated texts, and other ancillae in German-as-a-Second-Language courses at the college level, and asserts that electronic media deliver lexical assistance far more effectively than do traditional methods, using texts in ways previously unavailable. (MDM)

Will the Real Digital Native Please Stand Up?

ERIC Educational Resources Information Center

Waters, John K.

2011-01-01

A decade has passed since author, game designer, and educational thought leader Marc Prensky heralded the arrival of a new generation of students whose immersion in information technology distinguished them in fundamental ways from previous generations. Because they had spent their entire lives "surrounded by and using computers, videogames,…

Further Food for Thought on the "ABS Guide"

ERIC Educational Resources Information Center

Hussain, Simon

2012-01-01

This paper replies to points raised by the editors of the "ABS Guide", Huw Morris, Charles Harvey, Aidan Kelly and Michael Rowlinson (2011) "Accounting Education: an international journal", 20(6), pp. 561-573) in response to a paper published in a previous issue of "Accounting Education" (Hussain, S. (2011)…

Azoospermia in a Male with Klippel-Feil Anomaly.

PubMed

Uloko, Maria; Bearrick, Elizabeth; Bodie, Joshua

2017-07-01

Müllerian-duct aplasia, renal agenesis, and cervical somite dysplasia (MURCS) is a rare genetic disorder. Previously thought to be exclusive in females, there have now been a small number of case reports describing a male analogue. We describe a patient with obstructive azoospermia and Klippel-Feil anomaly.

Cambrian Sauk transgression in the Grand Canyon region redefined by detrital zircons

NASA Astrophysics Data System (ADS)

Karlstrom, Karl; Hagadorn, James; Gehrels, George; Matthews, William; Schmitz, Mark; Madronich, Lauren; Mulder, Jacob; Pecha, Mark; Giesler, Dominique; Crossey, Laura

2018-06-01

The Sauk transgression was one of the most dramatic global marine transgressions in Earth history. It is recorded by deposition of predominantly Cambrian non-marine to shallow marine sheet sandstones unconformably above basement rocks far into the interiors of many continents. Here we use dating of detrital zircons sampled from above and below the Great Unconformity in the Grand Canyon region to bracket the timing of the Sauk transgression at this classic location. We find that the Sixtymile Formation, long considered a Precambrian unit beneath the Great Unconformity, has maximum depositional ages that get younger up-section from 527 to 509 million years old. The unit contains angular unconformities and soft-sediment deformation that record a previously unknown period of intracratonic faulting and epeirogeny spanning four Cambrian stages. The overlying Tapeats Sandstone has youngest detrital zircon ages of 505 to 501 million years old. When linked to calibrated trilobite zone ages of greater than 500 million years old, these age constraints show that the marine transgression across a greater than 300-km-wide cratonic region took place during an interval 505 to 500 million years ago—more recently and more rapidly than previously thought. We redefine this onlap as the main Sauk transgression in the region. Mechanisms for this rapid flooding of the continent include thermal subsidence following the final breakup of Rodinia, combined with abrupt global eustatic changes driven by climate and/or mantle buoyancy modifications.

Extinction of Learned Fear Induces Hippocampal Place Cell Remapping

PubMed Central

Wang, Melissa E.; Yuan, Robin K.; Keinath, Alexander T.; Ramos Álvarez, Manuel M.

2015-01-01

The extinction of learned fear is a hippocampus-dependent process thought to embody new learning rather than erasure of the original fear memory, although it is unknown how these competing contextual memories are represented in the hippocampus. We previously demonstrated that contextual fear conditioning results in hippocampal place cell remapping and long-term stabilization of novel representations. Here we report that extinction learning also induces place cell remapping in C57BL/6 mice. Specifically, we observed cells that preferentially remapped during different stages of learning. While some cells remapped in both fear conditioning and extinction, others responded predominantly during extinction, which may serve to modify previous representations as well as encode new safe associations. Additionally, we found cells that remapped primarily during fear conditioning, which could facilitate reacquisition of the original fear association. Moreover, we also observed cells that were stable throughout learning, which may serve to encode the static aspects of the environment. The short-term remapping observed during extinction was not found in animals that did not undergo fear conditioning, or when extinction was conducted outside of the conditioning context. Finally, conditioning and extinction produced an increase in spike phase locking to the theta and gamma frequencies. However, the degree of remapping seen during conditioning and extinction only correlated with gamma synchronization. Our results suggest that the extinction learning is a complex process that involves both modification of pre-existing memories and formation of new ones, and these traces coexist within the same hippocampal representation. PMID:26085635

Horizontal Acquisition and Transcriptional Integration of Novel Genes in Mosquito-Associated Spiroplasma.

PubMed

Lo, Wen-Sui; Kuo, Chih-Horng

2017-12-01

Genetic differentiation among symbiotic bacteria is important in shaping biodiversity. The genus Spiroplasma contains species occupying diverse niches and is a model system for symbiont evolution. Previous studies have established that two mosquito-associated species have diverged extensively in their carbohydrate metabolism genes despite having a close phylogenetic relationship. Notably, although the commensal Spiroplasma diminutum lacks identifiable pathogenicity factors, the pathogenic Spiroplasma taiwanense was found to have acquired a virulence factor glpO and its associated genes through horizontal transfer. However, it is unclear if these acquired genes have been integrated into the regulatory network. In this study, we inferred the gene content evolution in these bacteria, as well as examined their transcriptomes in response to glucose availability. The results indicated that both species have many more gene acquisitions from the Mycoides-Entomoplasmataceae clade, which contains several important pathogens of ruminants, than previously thought. Moreover, several acquired genes have higher expression levels than the vertically inherited homologs, indicating possible functional replacement. Finally, the virulence factor and its functionally linked genes in S. taiwanense were up-regulated in response to glucose starvation, suggesting that these acquired genes are under expression regulation and the pathogenicity may be a stress response. In summary, although differential gene losses are a major process for symbiont divergence, gene gains are critical in counteracting genome degradation and driving diversification among facultative symbionts. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

Extinction of a fast-growing oyster and changing ocean circulation in Pliocene tropical America

NASA Astrophysics Data System (ADS)

Kirby, Michael X.; Jackson, Jeremy B. C.

2004-12-01

Ocean circulation changed profoundly in the late Cenozoic around tropical America as a result of constriction and final closure of the Central American seaway. In response, regional planktonic productivity is thought to have decreased in the Caribbean Sea. Previous studies have shown that shallow-marine communities reflect these changes by reorganizing from a suspension-feeder dominated community to a more carbonate-rich, phototrophic-based community. Although changes in diversity, abundance, and body size of various shallow-marine invertebrates have previously been examined, no study has specifically used growth rate in suspension feeders to examine the effect that changes in ocean circulation may have had on shallow-marine communities. Here we show that a fast-growing oyster went extinct concurrently with changes in ocean circulation and planktonic productivity in the Pliocene. Faster-growing Crassostrea cahobasensis went extinct, whereas slower-growing Crassostrea virginica and columbiensis survived to the Holocene. Miocene Pliocene C. cahobasensis grew 522% faster in shell carbonate and 251% faster in biomass relative to Quaternary C. virginica and C. columbiensis. Although differences in growth are due to proximate differences in environment, the disappearance of faster-growing C. cahobasensis from shallow-marine environments and the continued survival of slower-growing C. virginica and C. columbiensis in marginal-marine environments (e.g., estuaries, lagoons) is consistent with the view that concurrent changes in ocean circulation and declining primary production resulted in the restriction of Crassostrea to marginal-marine environments.

Creativity and sensory gating indexed by the P50: selective versus leaky sensory gating in divergent thinkers and creative achievers.

PubMed

Zabelina, Darya L; O'Leary, Daniel; Pornpattananangkul, Narun; Nusslock, Robin; Beeman, Mark

2015-03-01

Creativity has previously been linked with atypical attention, but it is not clear what aspects of attention, or what types of creativity are associated. Here we investigated specific neural markers of a very early form of attention, namely sensory gating, indexed by the P50 ERP, and how it relates to two measures of creativity: divergent thinking and real-world creative achievement. Data from 84 participants revealed that divergent thinking (assessed with the Torrance Test of Creative Thinking) was associated with selective sensory gating, whereas real-world creative achievement was associated with "leaky" sensory gating, both in zero-order correlations and when controlling for academic test scores in a regression. Thus both creativity measures related to sensory gating, but in opposite directions. Additionally, divergent thinking and real-world creative achievement did not interact in predicting P50 sensory gating, suggesting that these two creativity measures orthogonally relate to P50 sensory gating. Finally, the ERP effect was specific to the P50 - neither divergent thinking nor creative achievement were related to later components, such as the N100 and P200. Overall results suggest that leaky sensory gating may help people integrate ideas that are outside of focus of attention, leading to creativity in the real world; whereas divergent thinking, measured by divergent thinking tests which emphasize numerous responses within a limited time, may require selective sensory processing more than previously thought. Copyright © 2015 Elsevier Ltd. All rights reserved.

Navigating the interdependence dilemma: Attachment goals and the use of communal norms with potential close others.

PubMed

Bartz, Jennifer A; Lydon, John E

2006-07-01

Four studies investigated attachment in the context of new relationship development. Anxiously attached individuals overwhelmingly used communal norms and avoided using exchange norms when interacting with a potential close other; however, when a potential close other used communal norms, anxious individuals experienced increased interpersonal anxiety. Anxious individuals also used discrete communal behaviors to diagnose relationship potential. By contrast, secure individuals were more comfortable in potential communal situations. Moreover, implicit thoughts about closeness were associated with improved performance on a mental concentration task for secure individuals, whereas implicit closeness thoughts were associated with poorer performance for anxious individuals. Finally, avoidant individuals disliked the potential close other when the other used communal norms and downplayed relational motives for the other's communal behavior. Copyright 2006 APA, all rights reserved.

Boys with a simple delayed puberty reach their target height.

PubMed

Cools, B L M; Rooman, R; Op De Beeck, L; Du Caju, M V L

2008-01-01

Final height in boys with delayed puberty is thought to be below target height. This conclusion, however, is based on studies that included patients with genetic short stature. We therefore studied final height in a group of 33 untreated boys with delayed puberty with a target height >-1.5 SDS. Standing height, sitting height, weight and arm span width were measured in each patient. Final height was predicted by the method of Greulich and Pyle using the tables of Bailey and Pinneau for retarded boys at their bone age (PAH1) and the tables of Bailey and Pinneau for average boys plus six months (PAH2). Mean final height (175.8 +/- 6.5 cm) was appropriate for the mean target height (174.7 +/- 4.5 cm). The prediction method of Bailey and Pinneau overestimated the final height by 1.4 cm and the modified prediction method slightly underestimated the final height (-0.15 cm). Boys with untreated delayed puberty reach a final height appropriate for their target height. Final height was best predicted by the method of Bailey and Pinneau using the tables for average boys at their bone age plus six months. Copyright 2008 S. Karger AG, Basel.

Back to the future: autobiographical planning and the functionality of mind-wandering.

PubMed

Baird, Benjamin; Smallwood, Jonathan; Schooler, Jonathan W

2011-12-01

Given that as much as half of human thought arises in a stimulus independent fashion, it would seem unlikely that such thoughts would play no functional role in our lives. However, evidence linking the mind-wandering state to performance decrement has led to the notion that mind-wandering primarily represents a form of cognitive failure. Based on previous work showing a prospective bias to mind-wandering, the current study explores the hypothesis that one potential function of spontaneous thought is to plan and anticipate personally relevant future goals, a process referred to as autobiographical planning. The results confirm that the content of mind-wandering is predominantly future-focused, demonstrate that individuals with high working memory capacity are more likely to engage in prospective mind-wandering, and show that prospective mind-wandering frequently involves autobiographical planning. Together this evidence suggests that mind-wandering can enable prospective cognitive operations that are likely to be useful to the individual as they navigate through their daily lives. Copyright © 2011 Elsevier Inc. All rights reserved.

Multifocal nerve lesions and LZTR1 germline mutations in segmental schwannomatosis.

PubMed

Farschtschi, Said; Mautner, Victor-Felix; Pham, Mirko; Nguyen, Rosa; Kehrer-Sawatzki, Hildegard; Hutter, Sonja; Friedrich, Reinhard E; Schulz, Alexander; Morrison, Helen; Jones, David T W; Bendszus, Martin; Bäumer, Philipp

2016-10-01

Schwannomatosis is a genetic disorder characterized by the occurrence of multiple peripheral schwannomas. Segmental schwannomatosis is diagnosed when schwannomas are restricted to 1 extremity and is thought to be caused by genetic mosaicism. We studied 5 patients with segmental schwannomatosis through microstructural magnetic resonance neurography and mutation analysis of NF2, SMARCB1, and LZTR1. In 4 of 5 patients, subtle fascicular nerve lesions were detected in clinically unaffected extremities. Two patients exhibited LZTR1 germline mutations. This appears contrary to a simple concept of genetic mosaicism and suggests more complex and heterogeneous mechanisms underlying the phenotype of segmental schwannomatosis than previously thought. Ann Neurol 2016;80:625-628. © 2016 American Neurological Association.

Politically-focused intrusive thoughts and associated ritualistic behaviors in a community sample.

PubMed

Cepeda, Sandra L; McKay, Dean; Schneider, Sophie C; La Buissonnière-Ariza, Valérie; Egberts, Jolenthe T N E; McIngvale, Elizabeth; Goodman, Wayne K; Storch, Eric A

2018-05-01

A significant proportion of the U.S. population report increased stress attributed to the political climate following the controversial 2016 United States (U.S.) Presidential election. The political stressors paired with the growth in news consumption and social media-use could be a potential trigger for obsessive-compulsive-like symptoms specific to politics in some individuals. This study aimed to elucidate the rate of Politically-focused Intrusive Thoughts and associated Ritualistic Behaviors (PITRB), their demographic and clinical correlates, and the degree of association with political ideology. Survey data were collected using the crowdsourcing platform Mechanical Turk. A total of N = 484 individuals completed the survey. Measures of politically-focused intrusive thoughts and ritualistic behaviors, general obsessive-compulsive symptoms, depression, anxiety, anxiety control, worry, and disability were administered, as well as a measure of social and economic conservative affiliation. Results showed that a quarter of the sample (25.2%) had at least one PITRB more than once a day. PITRB was associated with all measures of psychopathology and disability. Finally, anxiety control moderated the relationship between PITRB and both anxiety and depression. No differences in psychopathology were found between major party affiliations. The findings suggest that politically-focused intrusive thoughts and ritualistic behaviors are associated with psychopathology domains in a manner comparable to general obsessive-compulsive symptoms. Copyright © 2018 Elsevier Ltd. All rights reserved.

Angry thoughts in Spanish drivers and their relationship with crash-related events. The mediation effect of aggressive and risky driving.

PubMed

Herrero-Fernández, David; Fonseca-Baeza, Sara

2017-09-01

Several studies have related aggressive and risky driving behaviours to accidents. However, the cognitive processes associated with driving aggression have received very little attention in the scientific literature. With the aim of shedding light on this topic, the present research was carried out on a sample of 414 participants in order to validate the Driver's Angry Thoughts Questionnaire (DATQ) with a sample of Spanish drivers and to test the hypothesis of the mediation effect of aggressive and risky driving on the relationship between drivers' angry thoughts and crash-related events. The results showed a good fit with the five-factor model of the questionnaire (Judgmental and Disbelieving Thinking, Pejorative Labelling and Verbally Aggressive Thinking, Revenge and Retaliatory Thinking, Physically Aggressive Thinking, and Coping Self-Instruction). Moreover, slight gender differences were observed in drivers' angry thoughts, with women scoring higher than men (η 2 =0.03). However, younger drivers had higher scores than older drivers in general (η 2 =0.06). Finally, several mediation effects of aggressive driving and risky driving on the relationship between aggressive thinking and the crash-related events were found. Implications of the results for research in traffic psychology and clinical assessment of aggressive drivers as well as limitations of the study are discussed. Copyright © 2017 Elsevier Ltd. All rights reserved.

A reevaluation of the anatomy of the jaw-closing system in the extant coelacanth Latimeria chalumnae

NASA Astrophysics Data System (ADS)

Dutel, Hugo; Herrel, Anthony; Clément, Gaël; Herbin, Marc

2013-11-01

The coelacanth Latimeria is the only extant representative of the Actinistia, a group of sarcopterygian fishes that originated in the Devonian. Moreover, it is the only extant vertebrate in which the neurocranium is divided into an anterior and a posterior portion that articulate by means of an intracranial joint. This joint is thought to be highly mobile, allowing an elevation of the anterior portion of the skull during prey capture. Here we provide a new description of the skull and jaw-closing system in Latimeria chalumnae in order to better understand its skull mechanics during prey capture. Based on a dissection and the CT scanning of an adult coelacanth, we provide a detailed description of the musculature and ligaments of the jaw system. We show that the m. adductor mandibulae is more complex than previously reported. We demonstrate that the basicranial muscle inserts more anteriorly than has been described previously, which has implications for its function. Moreover, the anterior insertion of the basicranial muscle does not correspond to the posterior tip of the tooth plate covering the parasphenoid, questioning previous inferences made on fossil coelacanths and other sarcopterygian fishes. Strong ligaments connect the anterior and the posterior portions of the skull at the level of the intracranial joint, as well as the notochord and the catazygals. These observations suggest that the intracranial joint is likely to be less mobile than previously thought and that its role during feeding merits to be reexamined.

Zachary-Fort Lauderdale pipeline construction and conversion project: final supplement to final environmental impact statement. Docket No. CP74-192

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

This Final Supplement to the Final Environmental Impact Statement (Final Supplement) evaluates the economic, engineering, and environmental aspects of newly developed alternatives to an abandonment/conversion project proposed by Florida Gas Transmission Company (Florida Gas). It also updates the staff's previous FEIS and studies revisions to the original proposal. Wherever possible, the staff has adopted portions of its previous FEIS in lieu of reprinting portions of that analysis which require no change. 60 references, 8 figures, 35 tables.

Sexy thoughts: effects of sexual cognitions on testosterone, cortisol, and arousal in women.

PubMed

Goldey, Katherine L; van Anders, Sari M

2011-05-01

Previous research suggests that sexual stimuli increase testosterone (T) in women and shows inconsistent effects of sexual arousal on cortisol (C), but effects of cognitive aspects of arousal, rather than behaviors or sensory stimuli, are unclear. The present study examined whether sexual thoughts affect T or C and whether hormonal contraceptive (HC) use moderated this effect, given mixed findings of HC use confounding hormone responses. Participants (79 women) provided a baseline saliva sample for radioimmunoassay. We created the Imagined Social Situation Exercise (ISSE) to test effects of imagining social interactions on hormones, and participants were assigned to the experimental (sexual) or one of three control (positive, neutral, stressful) conditions. Participants provided a second saliva sample 15 min post-activity. Results indicated that for women not using HCs, the sexual condition increased T compared to the stressful or positive conditions. In contrast, HC using women in the sexual condition had decreased T relative to the stressful condition and similar T to the positive condition. The effect was specific to T, as sexual thoughts did not change C. For participants in the sexual condition, higher baseline T predicted larger increases in sexual arousal but smaller increases in T, likely due to ceiling effects on T. Our results suggest that sexual thoughts change T but not C, baseline T levels and HC use may contribute to variation in the T response to sexual thoughts, and cognitive aspects of sexual arousal affect physiology. Copyright © 2010 Elsevier Inc. All rights reserved.

Drinking to Cope With Depressive Symptoms and Ruminative Thinking: A Multiple Mediation Model Among College Students.

PubMed

Bravo, Adrian J; Pearson, Matthew R; Henson, James M

2017-01-02

Understanding the potential psychosocial mechanisms that explain (i.e., mediate) the associations between depressive symptoms and alcohol-related problems can improve interventions targeting college students. The current research examined four distinct facets of rumination (e.g., problem-focused thoughts, counterfactual thinking, repetitive thoughts, and anticipatory thoughts) and drinking to cope motives as potential explanatory mechanisms by which depressive symptoms are associated with increased alcohol-related problems. Participants were undergraduate students from a large, southeastern university in the United States that consumed at least one drink per typical week in the previous month (n = 403). The majority of participants were female (n = 291; 72.2%), identified as being either White, non-Hispanic (n = 210; 52.1%), or African American (n = 110; 27.3%), and reported a mean age of 21.92 (SD = 5.75) years. Structural equation modeling was conducted examining the concurrent associations between depressive symptoms, rumination facets, drinking to cope motives, and alcohol-related problems (i.e., cross-sectional). There was one significant double-mediated association that suggested that increased depressive symptoms is associated with increased problem-focused thoughts, which is associated with higher drinking to cope motives and alcohol-related problems. Conclusions/Importance: Our results suggests that problem-focused thoughts at least partially explains the associations between depression and maladaptive coping (i.e., drinking to cope), which in turn is related to problematic drinking among college students. Limitations and future directions are discussed.

Neurally and mathematically motivated architecture for language and thought.

PubMed

Perlovsky, L I; Ilin, R

2010-01-01

Neural structures of interaction between thinking and language are unknown. This paper suggests a possible architecture motivated by neural and mathematical considerations. A mathematical requirement of computability imposes significant constraints on possible architectures consistent with brain neural structure and with a wealth of psychological knowledge. How language interacts with cognition. Do we think with words, or is thinking independent from language with words being just labels for decisions? Why is language learned by the age of 5 or 7, but acquisition of knowledge represented by learning to use this language knowledge takes a lifetime? This paper discusses hierarchical aspects of language and thought and argues that high level abstract thinking is impossible without language. We discuss a mathematical technique that can model the joint language-thought architecture, while overcoming previously encountered difficulties of computability. This architecture explains a contradiction between human ability for rational thoughtful decisions and irrationality of human thinking revealed by Tversky and Kahneman; a crucial role in this contradiction might be played by language. The proposed model resolves long-standing issues: how the brain learns correct words-object associations; why animals do not talk and think like people. We propose the role played by language emotionality in its interaction with thought. We relate the mathematical model to Humboldt's "firmness" of languages; and discuss possible influence of language grammar on its emotionality. Psychological and brain imaging experiments related to the proposed model are discussed. Future theoretical and experimental research is outlined.

Neurally and Mathematically Motivated Architecture for Language and Thought

PubMed Central

Perlovsky, L.I; Ilin, R

2010-01-01

Neural structures of interaction between thinking and language are unknown. This paper suggests a possible architecture motivated by neural and mathematical considerations. A mathematical requirement of computability imposes significant constraints on possible architectures consistent with brain neural structure and with a wealth of psychological knowledge. How language interacts with cognition. Do we think with words, or is thinking independent from language with words being just labels for decisions? Why is language learned by the age of 5 or 7, but acquisition of knowledge represented by learning to use this language knowledge takes a lifetime? This paper discusses hierarchical aspects of language and thought and argues that high level abstract thinking is impossible without language. We discuss a mathematical technique that can model the joint language-thought architecture, while overcoming previously encountered difficulties of computability. This architecture explains a contradiction between human ability for rational thoughtful decisions and irrationality of human thinking revealed by Tversky and Kahneman; a crucial role in this contradiction might be played by language. The proposed model resolves long-standing issues: how the brain learns correct words-object associations; why animals do not talk and think like people. We propose the role played by language emotionality in its interaction with thought. We relate the mathematical model to Humboldt’s “firmness” of languages; and discuss possible influence of language grammar on its emotionality. Psychological and brain imaging experiments related to the proposed model are discussed. Future theoretical and experimental research is outlined. PMID:21673788

Landscape Change in the Midwest: An Integrated Research and Development Program

Treesearch

Paul H. Gobster; Robert G. Haight; Dave Shriner

2000-01-01

Change happens. In the realm of forest landscapes, one of the great realizations of the late 20th century was that forests in the United States and elsewhere often are not the stable systems we once thought them to be, attaining a final "climax" stage through the process of succession. Advances in forest ecology show that landscape change is the rule rather...

The Problem of Representation and Experience in Quantum Mechanics

NASA Astrophysics Data System (ADS)

Ronde, Christian De

2014-03-01

In this paper we discuss the problem of representation and experience in quantum mechanics. We analyze the importance of metaphysics in physical thought and its relation to empiricism and analytic philosophy. We argue against both instrumentalism and scientific realism and claim that both perspectives tend to bypass the problem of representation and justify a "common sense" type experience. Finally, we present our expressionist conception of physics.

[Tyramine and serotonin syndromes. Pharmacological, medical and legal remarks].

PubMed

Toro-Martínez, Esteban

2005-01-01

The tyramine syndrome and the serotonin syndrome are a complex of signs and symptoms that are thought to be largely attributable to drug - drug interactions or drug - food interactions that enhances norepinephrine o serotonin activity. This article reviews: pharmacological basis of those syndromes; clinical features; forbidden foods, drug-drug interactions, and treatment options. Finally a set of legal recommendations are proposed to avoid liability litigations.

Children's Struggles with the Writing Process: Exploring Storytelling, Visual Arts, and Keyboarding to Promote Narrative Story Writing

ERIC Educational Resources Information Center

Dunn, Michael W.; Finley, Susan

2010-01-01

Composing text is an essential skill for students. Assignments, tests, and emailing are a few examples of the many tasks which require students to generate thoughts and put them into prose. For many students, choosing a topic, creating an outline, generating an initial draft, and making edits to produce a final copy is a fluid process which poses…

Ambivalence over emotional expression, intrusive thoughts, and posttraumatic stress symptoms among Chinese American breast cancer survivors.

PubMed

Lu, Qian; Yeung, Nelson; Man, Jenny; Gallagher, Matthew W; Chu, Qiao; Deen, Sidra H

2017-10-01

Posttraumatic stress symptoms (PTSS) are common among breast cancer survivors. However, the association and the underlying mediating mechanism between psychosocial factors and PTSS were rarely investigated among breast cancer survivors. Previous studies have suggested the importance of emotional expression in cancer survivors' PTSS. This study examined the association between ambivalence over emotional expression (AEE; defined as the conflict between the desire to express feelings and the fear of its consequences) and PTSS, and proposed intrusive thoughts as the mediators in such an association. We tested this proposed mediation model among Chinese breast cancer survivors whose culture discourages emotional expression. Participants were 118 Chinese-speaking breast cancer survivors in the USA, who were diagnosed with breast cancer of stages 0-III within the past 5 years. They completed questionnaires measuring their levels of AEE, PTSS, and intrusive thoughts. AEE was positively associated with intrusive thoughts (r = 0.43, p < 01), which were positively associated with the arousal and avoidance subscales of PTSS (r = 0.68 and r = 0.62, respectively, p < .01). Path analysis supported a partial mediation model with an indirect effect from AEE to the latent variable of PTSS (with both arousal and avoidance as indicators) via intrusive thoughts (β = 0.29; 95% CI= 0.18, 0.42) and the direct effect from AEE to the latent variable of PTSS (β = 0.21, 95% CI = 0.07, 0.35), all p < .001. Those who are highly ambivalent about emotion expression tend to have higher PTSS, and this may be partially due to the lack of opportunities to discuss emotional events, thereby increasing the repetitive cancer-related negative thoughts. Intervention for PTSS should consider helping cancer patients to develop adaptive emotional regulation strategies to reduce the detrimental effects of cancer-related intrusive thoughts.

The Best That Has Been Thought and Said?

ERIC Educational Resources Information Center

Alexander, Robin

2014-01-01

"FORUM" has marked the progress of the Cambridge Primary Review by three previous articles from Robin Alexander, the Review's director, and by critiques and responses from several others, notably "FORUM"'s Michael Armstrong. In 2013 the Review was superseded by the Cambridge Primary Review Trust, and this article is the text of…

Attitudes toward Nutrition, Locus of Control and Smoking Behavior.

ERIC Educational Resources Information Center

Corfield, V. Kilian; And Others

Research has shown that many behaviors previously thought to be purely psychological in origin do, in fact, have a physiological basis. To examine the relationship of smoking behavior to locus of control, and to attitudes toward, knowledge about, and behavior with respect to nutrition, 116 Canadian undergraduate students completed the Nutrition…

Study Links Learning Design to Changes in Knowledge, Beliefs, and Behaviors. Lessons from Research

ERIC Educational Resources Information Center

Killion, Joellen

2015-01-01

In this study of 16 teachers in two primary schools in the Netherlands, researchers built on findings from previous studies to demonstrate that a thoughtfully designed professional development program can be "effective and sustainable, if certain conditions are met" (p. 772) in changing teachers' knowledge, beliefs, perceived problems,…

Implications of HEAO-3 data for the acceleration and propagation of galactic cosmic rays

NASA Technical Reports Server (NTRS)

Ormes, J. F.; Protheroe, R. J.

1983-01-01

The energy dependence of the mean escape length of cosmic rays from the galaxy in the light of recent measurements of cosmic ray abundances from the Danish-French experiment on HEAO-3 is re-examined. The energy dependence is found to be steeper than previously thought.

Gamma-ray astronomy in the medium energy (10-50 MeV) range

NASA Technical Reports Server (NTRS)

Kniffen, D. A.; Bertsch, D. L.; Morris, D. J.; Palmeira, R. A. R.; Rao, K. R.

1977-01-01

To observe the medium energy component of the intense galactic center gamma-ray emission, two balloon flights of a medium energy gamma-ray spark chamber telescope were flown in Brazil in 1975. The results indicate the emission is higher than previously thought and above the predictions of a theoretical model proposed.

Using Concept Maps to Reveal Conceptual Typologies

ERIC Educational Resources Information Center

Hay, David B.; Kinchin, Ian M.

2006-01-01

Purpose: The purpose of this paper is to explain and develop a classification of cognitive structures (or typologies of thought), previously designated as spoke, chain and network thinking by Kinchin "et al." Design/methodology/approach: The paper shows how concept mapping can be used to reveal these conceptual typologies and endeavours to place…

Seroprevalence of Alkhurma and other hemorrhagic fever viruses, Saudi Arabia.

PubMed

Memish, Ziad A; Albarrak, Ali; Almazroa, Mohammad A; Al-Omar, Ibrahim; Alhakeem, Rafat; Assiri, Abdullah; Fagbo, Shamsudeen; MacNeil, Adam; Rollin, Pierre E; Abdullah, Nageeb; Stephens, Gwen

2011-12-01

A 2009 deployment of military units from several Saudi Arabian provinces to Jazan Province, Saudi Arabia, enabled us to evaluate exposure to Alkhurma, Crimean-Congo, dengue, and Rift Valley hemorrhagic fever viruses. Seroprevalence to all viruses was low; however, Alkhurma virus seroprevalence was higher (1.3%) and less geographically restricted than previously thought.

Developmental Origins of Infant Emotion Regulation: Mediation by Temperamental Negativity and Moderation by Maternal Sensitivity

ERIC Educational Resources Information Center

Thomas, Jenna C.; Letourneau, Nicole; Campbell, Tavis S.; Tomfohr-Madsen, Lianne; Giesbrecht, Gerald F.

2017-01-01

Emotion regulation is essential to cognitive, social, and emotional development and difficulties with emotion regulation portend future socioemotional, academic, and behavioral difficulties. There is growing awareness that many developmental outcomes previously thought to begin their development in the postnatal period have their origins in the…

Motivational Orientation, Error Monitoring, and Academic Performance in Middle Childhood: A Behavioral and Electrophysiological Investigation

ERIC Educational Resources Information Center

Fisher, Kelly R.; Marshall, Peter J.; Nanayakkara, Ajantha R.

2009-01-01

Previous research suggests that academic motivation orientation relates to students' causal interpretations about academic outcomes and their emotional reactions to those outcomes. The current study examines how student motivation may relate to certain neurophysiological systems that are thought to underlie the processing of successes and…

First record of Stenoheriades Cockerell in tropical Asia: Stenoheriades bifida, new species (Hymenoptera: Megachilidae)

USDA-ARS?s Scientific Manuscript database

The little known osmiine genus Stenoheriades, previously thought to be restricted to the Afrotropics and eastern Mediterranean, is here recorded from tropical Asia in the form of S. bifida, new species. This disjunct distribution adds to a growing list of endemic megachilids in southern India. The...

The Effects of Brain Damage on Visual Functioning in Children.

ERIC Educational Resources Information Center

Alexander, P. K.

1990-01-01

The review of research concluded that, although brain damage affects visual functioning, the prognosis for good functional vision after remedial intervention is better than previously thought. Although electrodiagnostic testing was found to be valuable, use of a combination of tests is recommended to obtain the most complete picture of brain…

Depression or Grief? The Experience of Caregivers of People with Dementia.

ERIC Educational Resources Information Center

Walker, Rebecca J.; Pomeroy, Elizabeth C.

1996-01-01

Study of caregivers of people with dementia suggests that the depression so frequently described in the literature may not be as severe or clinically significant as previously thought and may be described as anticipatory grief. Results may assist practitioners in planning and evaluating the effectiveness of clinical interventions. (RJM)

Conflict Adaptation and Congruency Sequence Effects to Social-Emotional Stimuli in Individuals with Autism Spectrum Disorders

ERIC Educational Resources Information Center

Worsham, Whitney; Gray, Whitney E.; Larson, Michael J.; South, Mikle

2015-01-01

Background: The modification of performance following conflict can be measured using conflict adaptation tasks thought to measure the change in the allocation of cognitive resources in order to reduce conflict interference and improve performance. While previous studies have suggested atypical processing during nonsocial cognitive control tasks,…

Will concern for biodiversity spell doom to tropical forest management?

Treesearch

A.E. Lugo

1999-01-01

Arguments against active tropical management are analyzed in light of available data and new research that shows tropical forests to be more resilient after disturbances than previously thought. Tropical forest management involves a diverse array of human activity embedded in a complex social and natural environment. Within this milieu, forest structure and composition...

Pedagogical Implications on Medical Students' Linguistic Needs

ERIC Educational Resources Information Center

Hwang, Yanling

2011-01-01

In this paper, an extended teaching implication is performed based on the study of medical students' linguistic needs in Tawian (Hwang, Lin, 2010). The aims of previous study were to provide a description of the linguistic needs and perceptions of medical students and faculty members in Taiwan. However, this paper put more thoughts on the…

PCB-153 AND BDE-47 INCREASE THYROXINE T4) CATABOLISM IN RAT AND HUMAN HEPATOCYTES

EPA Science Inventory

Previous studies demonstrate that in vivo exposure to 2,2',4,4',5,5'-hexachlorobiphenyl (PCB-153) and 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) decrease serum thyroxine (T4) levels in rats. This decrease is thought to occur through the induction of hepatic metabolizing enzymes ...

From the Fear of Death to the Fear of "Dissimilar Other": A Research in Elementary School Classrooms

ERIC Educational Resources Information Center

Leondari, A.; Magos, K.; Oikonomou, A.

2014-01-01

Social stereotyping and prejudice constitute pressing societal problems and have many causes. Terror Management Theory offers a compelling and heavily researched account of individuals' reactions towards "dissimilar others" when faced with thoughts of mortality. Building from previous research with adult samples, the present study aimed…

Cortical Gray Matter in Attention-Deficit/Hyperactivity Disorder: A Structural Magnetic Resonance Imaging Study

ERIC Educational Resources Information Center

Batty, Martin J.; Liddle, Elizabeth B.; Pitiot, Alain; Toro, Roberto; Groom, Madeleine J.; Scerif, Gaia; Liotti, Mario; Liddle, Peter F.; Paus, Tomas; Hollis, Chris

2010-01-01

Objective: Previous studies have shown smaller brain volume and less gray matter in children with attention-deficit/hyperactivity disorder (ADHD). Relatively few morphological studies have examined structures thought to subserve inhibitory control, one of the diagnostic features of ADHD. We examined one such region, the pars opercularis,…

The Graduate Outcome Project: Using Data from the Integrated Data Infrastructure Project

ERIC Educational Resources Information Center

Rees, Malcolm

2014-01-01

This paper reports on progress to date with a project underway in New Zealand involving the extraction of data from multiple government agencies that is then combined into one comprehensive longitudinal integrated dataset and made available to trial participants in a way never previously thought possible. The dataset includes school leaver…

Seeing Deep Structure from the Interactions of Surface Features

ERIC Educational Resources Information Center

Chi, Michelene T. H.; VanLehn, Kurt A.

2012-01-01

Transfer is typically thought of as requiring individuals to "see" what is the same in the deep structure between a new target problem and a previously encountered source problem, even though the surface features may be dissimilar. We propose that experts can "see" the deep structure by considering the first-order interactions…

Using Whole Language Materials in the Adult ESOL Classroom.

ERIC Educational Resources Information Center

Schiffer, Edward W.

A practicum explored the use of instructional materials based on the whole language approach to second language learning in adult English-as-a-Second-Language (ESL) instruction. The approach was implemented in a beginning ESL classroom at an adult education center that had previously used publisher textbooks, which were not thought to provide…

The floral hosts and distribution of a supposed creosote bush specialist, Colletes stepheni Timberlake (Hymenoptera: Colletidae)

USDA-ARS?s Scientific Manuscript database

Colletes stepheni Timberlake, previously thought to be a narrow oligolege of Larrea (creosote bush) of limited distribution in the Sonoran Desert, is found to be a much more widely distributed psammophile of the Sonoran, Mojave and Great Basin Deserts that utilizes two unrelated plant pollen sources...

Women, Education and the Big, Bad Society

ERIC Educational Resources Information Center

Thompson, Jane

2011-01-01

History has a habit of ignoring women. Thirty years ago one thought that re-emerging women's movement would never be dumped in the same way previous feminist generations were consigned to the dustbin of history. It took feminist activists and scholars; women trade unionists and health workers; feminist writers, publishers and artists; and the…

Defining Business Communication Using the Movie "The Insider" as Mediator of Students' Thought Processes.

ERIC Educational Resources Information Center

Rodriguez-Talavera, Leticia

Business communication is different from other domains in that its contextual meaning requires previous metacognitive mediation of signs. The communicative process in business is aimed at accomplishing a specific outcome. Various forms of meaning come into play in business communication such as denotative, connotative, stylistic, affective,…

Syndrome of mental retardation, seizures, hypotonic cerebral palsy and megalocorneae, recessively inherited.

PubMed

Neuhäuser, G; Kaveggia, E G; France, T D; Opitz, J M

1975-07-01

A previously apparently undescribed "syndrome" is reported in which megalocornea and iris anomalies are accompanied by minor facial and skeletal anomalies, severe mental retardation, hypotonia, and seizures. The condition was found in 3 siblings of one family and in 4 sporadic cases; it is thought to be recessively inherited.

Uncoupling protein expression in skeletal muscle and adipose tissue in response to in vivo porcine somatotropin treatment

USDA-ARS?s Scientific Manuscript database

The uncoupling proteins are thought to be involved in waste heat production, reducing the energy efficiency of growth in animals. Previous studies have detected their presence in swine and their regulation by the endocrine system. This study attempted to determine whether the uncoupling proteins 2...

Distracted by Your Mind? Individual Differences in Distractibility Predict Mind Wandering

ERIC Educational Resources Information Center

Forster, Sophie; Lavie, Nilli

2014-01-01

Attention may be distracted from its intended focus both by stimuli in the external environment and by internally generated task-unrelated thoughts during mind wandering. However, previous attention research has focused almost exclusively on distraction by external stimuli, and the extent to which mind wandering relates to external distraction is…

The consequences of human-driven ocean acidification for marine life.

PubMed

Doney, Scott

2009-05-08

Rising atmospheric carbon dioxide is causing a wholesale shift in surface seawater chemistry, potentially threatening many marine organisms that form shells and skeletons from calcium carbonate. Recent papers suggest that the biological consequences of ocean acidification already may be underway and may be more complex, nuanced and widespread than previously thought.

Early Career Teacher Attrition: New Thoughts on an Intractable Problem

ERIC Educational Resources Information Center

Gallant, Andrea; Riley, Philip

2014-01-01

Early career exit from teaching has reached epidemic proportions and appears intractable. Previous attempts to find solutions are yet to make much of an inroad. The aim of the research was to discover what nine beginning teachers required to remain in the classroom, by adopting a phenomenological approach. The authors identified participants'…

Rapid movement and instability of an invasive hybrid swarm

USGS Publications Warehouse

Glotzbecker, Gregory J.; Walters, David; Blum, Michael J.

2016-01-01

Unstable hybrid swarms that arise following the introduction of non-native species can overwhelm native congeners, yet the stability of invasive hybrid swarms has not been well documented over time. Here we examine genetic variation and clinal stability across a recently formed hybrid swarm involving native blacktail shiner (Cyprinella venusta) and non-native red shiner (C. lutrensis) in the Upper Coosa River basin, which is widely considered to be a global hotspot of aquatic biodiversity. Examination of phenotypic, multilocus genotypic, and mitochondrial haplotype variability between 2005 and 2011 revealed that the proportion of hybrids has increased over time, with more than a third of all sampled individuals exhibiting admixture in the final year of sampling. Comparisons of clines over time indicated that the hybrid swarm has been rapidly progressing upstream, but at a declining and slower pace than rates estimated from historical collection records. Clinal comparisons also showed that the hybrid swarm has been expanding and contracting over time. Additionally, we documented the presence of red shiner and hybrids farther downstream than prior studies have detected, which suggests that congeners in the Coosa River basin, including all remaining populations of the threatened blue shiner (Cyprinella caerulea), are at greater risk than previously thought.

Similar Ratios of Introns to Intergenic Sequence across Animal Genomes.

PubMed

Francis, Warren R; Wörheide, Gert

2017-06-01

One central goal of genome biology is to understand how the usage of the genome differs between organisms. Our knowledge of genome composition, needed for downstream inferences, is critically dependent on gene annotations, yet problems associated with gene annotation and assembly errors are usually ignored in comparative genomics. Here, we analyze the genomes of 68 species across 12 animal phyla and some single-cell eukaryotes for general trends in genome composition and transcription, taking into account problems of gene annotation. We show that, regardless of genome size, the ratio of introns to intergenic sequence is comparable across essentially all animals, with nearly all deviations dominated by increased intergenic sequence. Genomes of model organisms have ratios much closer to 1:1, suggesting that the majority of published genomes of nonmodel organisms are underannotated and consequently omit substantial numbers of genes, with likely negative impact on evolutionary interpretations. Finally, our results also indicate that most animals transcribe half or more of their genomes arguing against differences in genome usage between animal groups, and also suggesting that the transcribed portion is more dependent on genome size than previously thought. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

The complete chloroplast genome sequences of Lychnis wilfordii and Silene capitata and comparative analyses with other Caryophyllaceae genomes.

PubMed

Kang, Jong-Soo; Lee, Byoung Yoon; Kwak, Myounghai

2017-01-01

The complete chloroplast genomes of Lychnis wilfordii and Silene capitata were determined and compared with ten previously reported Caryophyllaceae chloroplast genomes. The chloroplast genome sequences of L. wilfordii and S. capitata contain 152,320 bp and 150,224 bp, respectively. The gene contents and orders among 12 Caryophyllaceae species are consistent, but several microstructural changes have occurred. Expansion of the inverted repeat (IR) regions at the large single copy (LSC)/IRb and small single copy (SSC)/IR boundaries led to partial or entire gene duplications. Additionally, rearrangements of the LSC region were caused by gene inversions and/or transpositions. The 18 kb inversions, which occurred three times in different lineages of tribe Sileneae, were thought to be facilitated by the intermolecular duplicated sequences. Sequence analyses of the L. wilfordii and S. capitata genomes revealed 39 and 43 repeats, respectively, including forward, palindromic, and reverse repeats. In addition, a total of 67 and 56 simple sequence repeats were discovered in the L. wilfordii and S. capitata chloroplast genomes, respectively. Finally, we constructed phylogenetic trees of the 12 Caryophyllaceae species and two Amaranthaceae species based on 73 protein-coding genes using both maximum parsimony and likelihood methods.

Low Temperature Rhombohedral Single Crystal SiGe Epitaxy on c-plane Sapphire

NASA Technical Reports Server (NTRS)

Duzik, Adam J.; Choi, Sang H.

2016-01-01

Current best practice in epitaxial growth of rhombohedral SiGe onto (0001) sapphire (Al2O3) substrate surfaces requires extreme conditions to grow a single crystal SiGe film. Previous models described the sapphire surface reconstruction as the overriding factor in rhombohedral epitaxy, requiring a high temperature Al-terminated surface for high quality films. Temperatures in the 850-1100 C range were thought to be necessary to get SiGe to form coherent atomic matching between the (111) SiGe plane and the (0001) sapphire surface. Such fabrication conditions are difficult and uneconomical, hindering widespread application. This work proposes an alternative model that considers the bulk sapphire structure and determines how the SiGe film nucleates and grows. Accounting for thermal expansion effects, calculations using this new model show that both pure Ge and SiGe can form single crystal films in the 450-550 C temperature range. Experimental results confirm these predictions, where x-ray diffraction and atomic force microscopy show the films fabricated at low temperature rival the high temperature films in crystallographic and surface quality. Finally, an explanation is provided for why films of comparable high quality can be produced in either temperature range.

Epidemiology of Helicobacter pylori infection.

PubMed

Leja, Mārcis; Axon, Anthony; Brenner, Hermann

2016-09-01

This review of recent publications related to the epidemiology of Helicobacter pylori highlights the origin of the infection, its changing prevalence, transmission, and outcome. A number of studies have addressed the ancestor roots of the bacteria, and the first genomewide analysis of bacterial strains suggests that its coexistence with humans is more ancient than previously thought. As opposed to the generally declining prevalence of H. pylori (including China and Japan), in Sweden, the prevalence of atrophic gastritis in the young population has risen. The prevalence of the infection remains high in the indigenous populations of the Arctic regions, and reinfection rates are high. A high prevalence is permanently found in the Siberian regions of Russia as well. Several studies, some of which used multiplex serology, addressed prevalence of and risks associated with various H. pylori serotypes, thereby enabling more precise risk assessment. Transmission of H. pylori was discussed, specifically fecal-oral transmission and the use of well-water and other unpurified water. Finally, the long-term course of H. pylori infection was considered, with an estimated 89% of noncardia gastric cancer cases being attributable to the infection. © 2016 John Wiley & Sons Ltd.

Personal and social factors that influence pro-environmental concern and behaviour: a review.

PubMed

Gifford, Robert; Nilsson, Andreas

2014-06-01

We review the personal and social influences on pro-environmental concern and behaviour, with an emphasis on recent research. The number of these influences suggests that understanding pro-environmental concern and behaviour is far more complex than previously thought. The influences are grouped into 18 personal and social factors. The personal factors include childhood experience, knowledge and education, personality and self-construal, sense of control, values, political and world views, goals, felt responsibility, cognitive biases, place attachment, age, gender and chosen activities. The social factors include religion, urban-rural differences, norms, social class, proximity to problematic environmental sites and cultural and ethnic variations We also recognize that pro-environmental behaviour often is undertaken based on none of the above influences, but because individuals have non-environmental goals such as to save money or to improve their health. Finally, environmental outcomes that are a result of these influences undoubtedly are determined by combinations of the 18 categories. Therefore, a primary goal of researchers now should be to learn more about how these many influences moderate and mediate one another to determine pro-environmental behaviour. © 2014 International Union of Psychological Science.

Fourier transform-infrared studies of thin H2SO4/H2O films: Formation, water uptake, and solid-liquid phase changes

NASA Technical Reports Server (NTRS)

Middlebrook, Ann M.; Iraci, Laura T.; Mcneill, Laurie S.; Koehler, Birgit G.; Wilson, Margaret A.; Saastad, Ole W.; Tolbert, Margaret A.; Hanson, David R.

1993-01-01

Fourier transform-infrared (FTIR) spectroscopy was used to examine films representative of stratospheric sulfuric acid aerosols. Thin films of sulfuric acid were formed in situ by the condensed phase reaction of SO3 with H2O. FTIR spectra show that the sulfuric acid films absorb water while cooling in the presence of water vapor. Using stratospheric water pressures, the most dilute solutions observed were greater than 40 wt % before simultaneous ice formation and sulfuric acid freezing occurred. FTIR spectra also revealed that the sulfuric acid films crystallized mainly as sulfuric acid tetrahydrate (SAT). Crystallization occurred either when the composition was about 60 wt% H2SO4 or after ice formed on the films at temperatures 1-4 K below the ice frost point. Finally, we determined that the melting point for SAT depended on the background water pressure and was 216-219 K in the presence of 4 x 10(exp -4) Torr H2O. Our results suggest that once frozen, sulfuric acid aerosols in the stratosphere are likely to melt at these temperatures, 30 K colder than previously thought.

The time course of corticospinal excitability during a simple reaction time task.

PubMed

Kennefick, Michael; Maslovat, Dana; Carlsen, Anthony N

2014-01-01

The production of movement in a simple reaction time task can be separated into two time periods: the foreperiod, which is thought to include preparatory processes, and the reaction time interval, which includes initiation processes. To better understand these processes, transcranial magnetic stimulation has been used to probe corticospinal excitability at various time points during response preparation and initiation. Previous research has shown that excitability decreases prior to the "go" stimulus and increases following the "go"; however these two time frames have been examined independently. The purpose of this study was to measure changes in CE during both the foreperiod and reaction time interval in a single experiment, relative to a resting baseline level. Participants performed a button press movement in a simple reaction time task and excitability was measured during rest, the foreperiod, and the reaction time interval. Results indicated that during the foreperiod, excitability levels quickly increased from baseline with the presentation of the warning signal, followed by a period of stable excitability leading up to the "go" signal, and finally a rapid increase in excitability during the reaction time interval. This excitability time course is consistent with neural activation models that describe movement preparation and response initiation.

In Silico Design of DNP Polarizing Agents: Can Current Dinitroxides Be Improved?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Perras, Frédéric A.; Sadow, Aaron; Pruski, Marek

Numerical calculations of enhancement factors offered by dynamic nuclear polarization in solids under magic angle spinning (DNP-MAS) were performed to determine the optimal EPR parameters for a dinitroxide polarizing agent. We found that the DNP performance of a biradical is more tolerant to the relative orientation of the two nitroxide moieties than previously thought. In general, any condition in which the gyy tensor components of both radicals are perpendicular to one another is expected to have near-optimal DNP performance. These results highlight the important role of the exchange coupling, which can lessen the sensitivity of DNP performance to the inter-radicalmore » distance, but also lead to lower enhancements when the number of atoms in the linker becomes less than three. Finally, the calculations showed that the electron T1e value should be near 500μs to yield optimal performance. Importantly, the newest polarizing agents already feature all of the qualities of the optimal polarizing agent, leaving little room for further improvement. Further research into DNP polarizing agents should then target non-nitroxide radicals, as well as improvements in sample formulations to advance high-temperature DNP and limit quenching and reactivity.« less

Direct uptake of soil nitrogen by mosses

PubMed Central

Ayres, Edward; van der Wal, René; Sommerkorn, Martin; Bardgett, Richard D

2006-01-01

Mosses are one of the most diverse and widespread groups of plants and often form the dominant vegetation in montane, boreal and arctic ecosystems. However, unlike higher plants, mosses lack developed root and vascular systems, which is thought to limit their access to soil nutrients. Here, we test the ability of two physiologically and taxonomically distinct moss species to take up soil- and wet deposition-derived nitrogen (N) in natural intact turfs using stable isotopic techniques (15N). Both species exhibited increased concentrations of shoot 15N when exposed to either soil- or wet deposition-derived 15N, demonstrating conclusively and for the first time, that mosses derive N from the soil. Given the broad physiological and taxonomic differences between these moss species, we suggest soil N uptake may be common among mosses, although further studies are required to test this prediction. Soil N uptake by moss species may allow them to compete for soil N in a wide range of ecosystems. Moreover, since many terrestrial ecosystems are N limited, soil N uptake by mosses may have implications for plant community structure and nutrient cycling. Finally, soil N uptake may place some moss species at greater risk from N pollution than previously appreciated. PMID:17148384

Statistical projection effects in a hydrodynamic pilot-wave system

NASA Astrophysics Data System (ADS)

Sáenz, Pedro J.; Cristea-Platon, Tudor; Bush, John W. M.

2018-03-01

Millimetric liquid droplets can walk across the surface of a vibrating fluid bath, self-propelled through a resonant interaction with their own guiding or `pilot' wave fields. These walking droplets, or `walkers', exhibit several features previously thought to be peculiar to the microscopic, quantum realm. In particular, walkers confined to circular corrals manifest a wave-like statistical behaviour reminiscent of that of electrons in quantum corrals. Here we demonstrate that localized topological inhomogeneities in an elliptical corral may lead to resonant projection effects in the walker's statistics similar to those reported in quantum corrals. Specifically, we show that a submerged circular well may drive the walker to excite specific eigenmodes in the bath that result in drastic changes in the particle's statistical behaviour. The well tends to attract the walker, leading to a local peak in the walker's position histogram. By placing the well at one of the foci, a mode with maxima near the foci is preferentially excited, leading to a projection effect in the walker's position histogram towards the empty focus, an effect strongly reminiscent of the quantum mirage. Finally, we demonstrate that the mean pilot-wave field has the same form as the histogram describing the walker's statistics.

Insecticide resistance resulting from sequential selection of houseflies in the field by organophosphorus compounds*

PubMed Central

Georghiou, George P.; Hawley, Marilyn K.

1971-01-01

Although cross-resistance in houseflies to the organophosphates has eliminated numerous potentially useful compounds from field use, the ”subgroup” specificity of this phenomenon has permitted housefly control to be carried out for nearly a quarter of a century by changing from one toxicant to another within this class of insecticides. A question of considerable importance in insect control is whether the development of resistance to one subgroup of organophosphates will be at the expense of resistance to a subgroup applied previously. The development over several years of resistance in a field population selected sequentially by a number of organophosphates was studied. It was observed that the resistance spectrum expanded progressively to include, finally, organophosphates originally thought to belong to more than one subgroup—namely, malathion (resistance greater than 100 times), fenchlorphos (114 times), diazinon (163 times), coumaphos (greater than 100 times), Ciodrin (greater than 100 times), fenthion (18 times) and naled (9.3 times). Resistance to each compound continued to rise to levels considerably higher than those achieved at the time when the field use of the compound ended. The possible coexistence of subgroup cross-resistance in a population is discussed in the light of these results. PMID:5316852

Formation of an Oceanic Transform Fault During Continental Rifting

NASA Astrophysics Data System (ADS)

Illsley-Kemp, F.; Bull, J. M.; Keir, D.; Gerya, T.; Pagli, C.; Gernon, T.; Ayele, A.; Goitom, B.; Hammond, J. O. S.; Kendall, J. M.

2017-12-01

We integrate evidence from surface faults, geodetic measurements, local seismicity, and 3D numerical modelling of the subaerial Afar continental rift to show that an oceanic-style transform fault is forming during the final stages of continental breakup. Transform faults are a fundamental tenet of plate tectonics, connecting offset extensional segments of mid-ocean ridges, and are vital in palaeotectonic reconstructions of passive margins. The current consensus is that transform faults initiate after the onset of seafloor spreading. However this inference has been difficult to test given the lack of observations of transform fault formation. We present the first direct observation of transform fault initiation, and shed unprecedented light on their formation mechanisms. We demonstrate that they originate during late-stage continental rifting, earlier in the rifting cycle than previously thought. Our results have important implications for reconstructing the breakup history of the continents. Palaeotectonic reconstructions that use transform fault terminations as an indicator of the continent-ocean boundary may have placed the continent-ocean boundary landward of its true location. This will have led to an overestimation of the age of continental breakup of between 8-18 Myr. Our results therefore have significant implications for studies that rely on accurate dating of continental breakup events.

Stem Cell Research and Clinical Translation: A Roadmap about Good Clinical Practice and Patient Care

PubMed Central

Scopetti, Matteo; Gatto, Vittorio

2017-01-01

The latest research achievements in the field of stem cells led in 2016 to the publication of “Guidelines for Stem Cell Research and Clinical Translation” by the International Society for Stem Cell Research (ISSCR). Updating the topics covered in previous publications, the new recommendations offer interesting ethical and scientific insights. Under the common principles of research integrity, protection of patient's welfare, respect for the research subjects, transparency and social justice, the centrality of good clinical practice, and informed consent in research and translational medicine is supported. The guidelines implement the abovementioned publications, requiring rigor in all areas of research, promoting the validity of the scientific activity results and emphasizing the need for an accurate and efficient public communication. This paper aims to analyze the aforementioned guidelines in order to provide a valid interpretive tool for experts. In particular, a research activity focused on the bioethical, scientific, and social implications of the new recommendations is carried out in order to provide food for thought. Finally, as an emerging issue of potential impact of current guidelines, an overview on implications of compensation for egg donation is offered. PMID:29090010

UPSS and G2

NASA Technical Reports Server (NTRS)

Dito, Scott J.

2014-01-01

The Universal Propellant Servicing System (UPSS) is a dedicated mobile launcher propellant delivery method that will minimize danger and complexity in order to allow vehicles to be serviced and ultimately launched from a variety of locations previously not seen fit for space launch. The UPPS/G2 project is the development of a model, simulation, and ultimately a working application that will control and monitor the cryogenic fluid delivery to the rocket for testing purposes. To accomplish this, the project is using the programming language/environment Gensym G2. The environment is an all-inclusive application that allows development, testing, modeling, and finally operation of the unique application through graphical and programmatic methods. We have learned G2 through classes and trial-and-error, and are now in the process of building the application that will soon be able to be tested on apparatuses here at Kennedy Space Center, and eventually on the actual unit. The UPSS will bring near-autonomous control of launches to those that need it, as well it will be a great addition to NASA and KSC's operational viability and the opportunity to bring space launches to parts of the world, and in time constraints, once not thought possible.

In Silico Design of DNP Polarizing Agents: Can Current Dinitroxides Be Improved?

DOE PAGES

Perras, Frédéric A.; Sadow, Aaron; Pruski, Marek

2017-06-09

Numerical calculations of enhancement factors offered by dynamic nuclear polarization in solids under magic angle spinning (DNP-MAS) were performed to determine the optimal EPR parameters for a dinitroxide polarizing agent. We found that the DNP performance of a biradical is more tolerant to the relative orientation of the two nitroxide moieties than previously thought. In general, any condition in which the gyy tensor components of both radicals are perpendicular to one another is expected to have near-optimal DNP performance. These results highlight the important role of the exchange coupling, which can lessen the sensitivity of DNP performance to the inter-radicalmore » distance, but also lead to lower enhancements when the number of atoms in the linker becomes less than three. Finally, the calculations showed that the electron T1e value should be near 500μs to yield optimal performance. Importantly, the newest polarizing agents already feature all of the qualities of the optimal polarizing agent, leaving little room for further improvement. Further research into DNP polarizing agents should then target non-nitroxide radicals, as well as improvements in sample formulations to advance high-temperature DNP and limit quenching and reactivity.« less

End-word dysfluencies in young children: a clinical report.

PubMed

MacMillan, Verity; Kokolakis, Artemi; Sheedy, Stacey; Packman, Ann

2014-01-01

We report on 12 children with end-word dysfluencies (EWDs). Our aim was to document this little-reported type of dysfluency and to develop a possible explanation for them and how they relate to developmental stuttering. Audio recordings were made for 9 of the 12 children in the study. The EWDs were identified by consensus of two specialist speech pathologists and confirmed on acoustic displays. A segment of participant 1's speech was transcribed, including phonetic transcription of EWDs. The EWDs typically consisted of repetitions of the nucleus and/or the coda. However, there were also some EWDs that consisted of fixed postures on the nucleus (when in final position) or coda. We also report on the infrequent occurrence of broken words. Ten of the 12 children also stuttered, with 9 of them coming from four families, each with a history of stuttering. This study indicates that EWDs may be more prevalent than previously thought, but they may go largely unnoticed due to their perceptually fleeting nature. The hypothesis was developed that EWDs be regarded as another type of developmental dysfluency, along with stuttering and cluttering. Ideas for further research are suggested. © 2014 S. Karger AG, Basel.

The versatile landscape of haematopoiesis: are leukaemia stem cells as versatile?

PubMed

Brown, Geoffrey; Hughes, Philip J; Ceredig, Rhodri

2012-01-01

Since the early 1980s, developing haematopoietic cells have been categorised into three well-defined compartments: multi-potent haematopoietic stem cells (HSC), which are able to self-renew, followed by haematopoietic progenitor cells (HPC), which undergo decision-making and age as they divide rather than self-renew, and the final compartment of functional blood and immune cells. The classic model of haematopoiesis divides cells into two families, myeloid and lymphoid, and dictates a route to a particular cell fate. New discoveries question these long-held principles, including: (i) the identification of lineage-biased cells that self-renew; (ii) a strict myeloid/lymphoid dichotomy is refuted by the existence of progenitors with lymphoid potential and an incomplete set of myeloid potentials; (iii) there are multiple routes to some end cell types; and (iv) thymocyte progenitor cells that have progressed some way along this pathway retain clandestine myeloid options. In essence, the progeny of HSC are more versatile and the process of haematopoiesis is more flexible than previously thought. Here we examine this new way of viewing haematopoiesis and the impact of rewriting an account of haematopoiesis on our understanding of what goes awry in leukaemia.

Revisiting Stephan's Quintet with deep optical images

NASA Astrophysics Data System (ADS)

Duc, Pierre-Alain; Cuillandre, Jean-Charles; Renaud, Florent

2018-03-01

Stephan's Quintet, a compact group of galaxies, is often used as a laboratory to study a number of phenomena, including physical processes in the interstellar medium, star formation, galaxy evolution, and the formation of fossil groups. As such, it has been subject to intensive multiwavelength observation campaigns. Yet, models lack constrains to pin down the role of each galaxy in the assembly of the group. We revisit here this system with multiband deep optical images obtained with MegaCam on the Canada-France-Hawaii Telescope (CFHT), focusing on the detection of low surface brightness (LSB) structures. They reveal a number of extended LSB features, some new, and some already visible in published images but not discussed before. An extended diffuse, reddish, lopsided, halo is detected towards the early-type galaxy NGC 7317, the role of which had so far been ignored in models. The presence of this halo made of old stars may indicate that the group formed earlier than previously thought. Finally, a number of additional diffuse filaments are visible, some close to the foreground galaxy NGC 7331 located in the same field. Their structure and association with mid-infrared emission suggest contamination by emission from Galactic cirrus.

[Double-sided juvenile osteochondritis dissecans of the lateral femoral condyle in a 15-year-old boy].

PubMed

Nordkamp, R A G; van Rensen, I H T; Sala, H A G M; van Mourik, J B A

2007-07-21

A 15-year-old boy of Turkish origin presented with a painful swollen left knee. An X-ray revealed osteochondritis dissecans of the lateral femoral condyle. Arthrotomy was performed and the fragment was fixated with tissue glue and 2 absorbable pins. Eight months later, a large recurrent osteochondral fragment of the lateral femoral condyle was seen on X-ray. The patient was re-operated, during which operation the fragment was found and fixated with three compression screws. One year after the first operation the patient developed similar complaints in the contralateral knee; this knee also contained osteochondral fragments necessitating surgery. Osteochondritis dissecans of the knee is a multifactorial disease in which part of the cartilage of the femoral condyle becomes unattached from the subchondral stratum, usually on the lateral side of the medial femoral condyle. Initially, an inflammatory reaction was thought to be the cause of osteochondritis dissecans. Because of the lack of white blood cells, a previous trauma is a better explanation for the ultimate loosening of the cartilage. The treatments that are described for osteochondritis dissecans are conservative treatment, operative fixation, with or without subsequent chondrocyte transplantation or osteochondral autograft transplantation, and finally microfracturing.

N6-methyladenine: a conserved and dynamic DNA mark

PubMed Central

O’Brown, Zach Klapholz; Greer, Eric Lieberman

2017-01-01

Chromatin, consisting of deoxyribonucleic acid (DNA) wrapped around histone proteins, facilitates DNA compaction and allows identical DNA code to confer many different cellular phenotypes. This biological versatility is accomplished in large part by post-translational modifications to histones and chemical modifications to DNA. These modifications direct the cellular machinery to expand or compact specific chromatin regions, and mark regions of the DNA as important for cellular functions. While each of the four bases that make up DNA can be modified (Iyer et al. 2011), this chapter will focus on methylation of the 6th position on adenines (6mA), as this modification has been poorly characterized in recently evolved eukaryotes but shows promise as a new conserved layer of epigenetic regulation. 6mA was previously thought to be restricted to unicellular organisms, but recent work has revealed its presence in more recently evolved metazoa. Here, we will briefly describe the history of 6mA, examine its evolutionary conservation, and evaluate the current methods for detecting 6mA. We will discuss the enzymes that bind and regulate this mark and finally examine known and potential functions of 6mA in eukaryotes. PMID:27826841

Advances in cholangiocyte immunobiology

PubMed Central

Syal, Gaurav; Fausther, Michel

2012-01-01

Cholangiocytes, or bile duct epithelia, were once thought to be the simple lining of the conduit system comprising the intra- and extrahepatic bile ducts. Growing experimental evidence demonstrated that cholangiocytes are in fact the first line of defense of the biliary system against foreign substances. Experimental advances in recent years have unveiled previously unknown roles of cholangiocytes in both innate and adaptive immune responses. Cholangiocytes can release inflammatory modulators in a regulated fashion. Moreover, they express specialized pattern-recognizing molecules that identify microbial components and activate intracellular signaling cascades leading to a variety of downstream responses. The cytokines secreted by cholangiocytes, in conjunction with the adhesion molecules expressed on their surface, play a role in recruitment, localization, and modulation of immune responses in the liver and biliary tract. Cholangiocyte survival and function is further modulated by cytokines and inflammatory mediators secreted by immune cells and cholangiocytes themselves. Because cholangiocytes act as professional APCs via expression of major histocompatibility complex antigens and secrete antimicrobial peptides in bile, their role in response to biliary infection is critical. Finally, because cholangiocytes release mediators critical to myofibroblastic differentiation of portal fibroblasts and hepatic stellate cells, cholangiocytes may be essential in the pathogenesis of biliary cirrhosis. PMID:22961800

Advances in cholangiocyte immunobiology.

PubMed

Syal, Gaurav; Fausther, Michel; Dranoff, Jonathan A

2012-11-15

Cholangiocytes, or bile duct epithelia, were once thought to be the simple lining of the conduit system comprising the intra- and extrahepatic bile ducts. Growing experimental evidence demonstrated that cholangiocytes are in fact the first line of defense of the biliary system against foreign substances. Experimental advances in recent years have unveiled previously unknown roles of cholangiocytes in both innate and adaptive immune responses. Cholangiocytes can release inflammatory modulators in a regulated fashion. Moreover, they express specialized pattern-recognizing molecules that identify microbial components and activate intracellular signaling cascades leading to a variety of downstream responses. The cytokines secreted by cholangiocytes, in conjunction with the adhesion molecules expressed on their surface, play a role in recruitment, localization, and modulation of immune responses in the liver and biliary tract. Cholangiocyte survival and function is further modulated by cytokines and inflammatory mediators secreted by immune cells and cholangiocytes themselves. Because cholangiocytes act as professional APCs via expression of major histocompatibility complex antigens and secrete antimicrobial peptides in bile, their role in response to biliary infection is critical. Finally, because cholangiocytes release mediators critical to myofibroblastic differentiation of portal fibroblasts and hepatic stellate cells, cholangiocytes may be essential in the pathogenesis of biliary cirrhosis.

Partitioning of organic carbon among density fractions in surface sediments of Fiordland, New Zealand

NASA Astrophysics Data System (ADS)

Cui, Xingqian; Bianchi, Thomas S.; Hutchings, Jack A.; Savage, Candida; Curtis, Jason H.

2016-03-01

Transport of particles plays a major role in redistributing organic carbon (OC) along coastal regions. In particular, the global importance of fjords as sites of carbon burial has recently been shown to be even more important than previously thought. In this study, we used six surface sediments from Fiordland, New Zealand, to investigate the transport of particles and OC based on density fractionation. Bulk, biomarker, and principle component analysis were applied to density fractions with ranges of <1.6, 1.6-2.0, 2.0-2.5, and >2.5 g cm-3. Our results found various patterns of OC partitioning at different locations along fjords, likely due to selective transport of higher density but smaller size particles along fjord head-to-mouth transects. We also found preferential leaching of certain biomarkers (e.g., lignin) over others (e.g., fatty acids) during the density fractionation procedure, which altered lignin-based degradation indices. Finally, our results indicated various patterns of OC partitioning on density fractions among different coastal systems. We further propose that a combination of particle size-density fractionation is needed to better understand transport and distribution of particles and OC.

Research Update: A minimal region of squid reflectin for vapor-induced light scattering

NASA Astrophysics Data System (ADS)

Dennis, Patrick B.; Singh, Kristi M.; Vasudev, Milana C.; Naik, Rajesh R.; Crookes-Goodson, Wendy J.

2017-12-01

Reflectins are a family of proteins found in the light manipulating cells of cephalopods. These proteins are made up of a series of conserved repeats that contain highly represented amino acids thought to be important for function. Previous studies demonstrated that recombinant reflectins cast into thin films produced structural colors that could be dynamically modulated via changing environmental conditions. In this study, we demonstrate light scattering from reflectin films following exposure to a series of water vapor pulses. Analysis of film surface topography shows that the induction of light scatter is accompanied by self-assembly of reflectins into micro- and nanoscale features. Using a reductionist strategy, we determine which reflectin repeats and sub-repeats are necessary for these events following water vapor pulsing. With this approach, we identify a singly represented, 23-amino acid region in reflectins as being sufficient to recapitulate the light scattering properties observed in thin films of the full-length protein. Finally, the aqueous stability of reflectin films is leveraged to show that pre-exposure to buffers of varying pH can modulate the ability of water vapor pulses to induce light scatter and protein self-assembly.

Stem Cell Research and Clinical Translation: A Roadmap about Good Clinical Practice and Patient Care.

PubMed

Frati, Paola; Scopetti, Matteo; Santurro, Alessandro; Gatto, Vittorio; Fineschi, Vittorio

2017-01-01

The latest research achievements in the field of stem cells led in 2016 to the publication of "Guidelines for Stem Cell Research and Clinical Translation" by the International Society for Stem Cell Research (ISSCR). Updating the topics covered in previous publications, the new recommendations offer interesting ethical and scientific insights. Under the common principles of research integrity, protection of patient's welfare, respect for the research subjects, transparency and social justice, the centrality of good clinical practice, and informed consent in research and translational medicine is supported. The guidelines implement the abovementioned publications, requiring rigor in all areas of research, promoting the validity of the scientific activity results and emphasizing the need for an accurate and efficient public communication. This paper aims to analyze the aforementioned guidelines in order to provide a valid interpretive tool for experts. In particular, a research activity focused on the bioethical, scientific, and social implications of the new recommendations is carried out in order to provide food for thought. Finally, as an emerging issue of potential impact of current guidelines, an overview on implications of compensation for egg donation is offered.

Nano-Satellite Secondary Spacecraft on Deep Space Missions

NASA Technical Reports Server (NTRS)

Klesh, Andrew T.; Castillo-Rogez, Julie C.

2012-01-01

NanoSat technology has opened Earth orbit to extremely low-cost science missions through a common interface that provides greater launch accessibility. They have also been used on interplanetary missions, but these missions have used one-off components and architectures so that the return on investment has been limited. A natural question is the role that CubeSat-derived NanoSats could play to increase the science return of deep space missions. We do not consider single instrument nano-satellites as likely to complete entire Discovery-class missions alone,but believe that nano-satellites could augment larger missions to significantly increase science return. The key advantages offered by these mini-spacecrafts over previous planetary probes is the common availability of advanced subsystems that open the door to a large variety of science experiments, including new guidance, navigation and control capabilities. In this paper, multiple NanoSat science applications are investigated, primarily for high risk/high return science areas. We also address the significant challenges and questions that remain as obstacles to the use of nano-satellites in deep space missions. Finally, we provide some thoughts on a development roadmap toward interplanetary usage of NanoSpacecraft.

How Orthogonal Are the Big Two of Social Perception? On the Curvilinear Relation Between Agency and Communion.

PubMed

Imhoff, Roland; Koch, Alex

2017-01-01

Humans make sense of their social environment by forming impressions of others that allow predicting others' actions. In this process of social perception, two types of information carry pivotal importance: other entities' communion (i.e., warmth and trustworthiness) and agency (i.e., status and power). Although commonly thought of as orthogonal dimensions, we propose that these Big Two of social perception are curvilinearly related. Specifically, as we delineate from four different theoretical explanations, impressions of communion should peak at average agency, while entities too high or too low on agency should be perceived as low on communion. We show this pattern for social groups across one novel and five previously published data sets, including a meta-analysis of the most comprehensive data collection in the group perception literature, consisting of 36 samples from more than 20 countries. Addressing the generalizability of this curvilinear relation, we then report recent and unpublished experiments establishing the effect for the perception of individuals and animals. On the basis of the proposed curvilinear relation, we revisit the primacy of processing communion (rather than agency) information. Finally, we discuss the possibility of a more general curvilinear relation between communion and dimensions other than agency.

Contribution of the cyclic nucleotide gated channel subunit, CNG-3, to olfactory plasticity in Caenorhabditis elegans.

PubMed

O'Halloran, Damien M; Altshuler-Keylin, Svetlana; Zhang, Xiao-Dong; He, Chao; Morales-Phan, Christopher; Yu, Yawei; Kaye, Julia A; Brueggemann, Chantal; Chen, Tsung-Yu; L'Etoile, Noelle D

2017-03-13

In Caenorhabditis elegans, the AWC neurons are thought to deploy a cGMP signaling cascade in the detection of and response to AWC sensed odors. Prolonged exposure to an AWC sensed odor in the absence of food leads to reversible decreases in the animal's attraction to that odor. This adaptation exhibits two stages referred to as short-term and long-term adaptation. Previously, the protein kinase G (PKG), EGL-4/PKG-1, was shown necessary for both stages of adaptation and phosphorylation of its target, the beta-type cyclic nucleotide gated (CNG) channel subunit, TAX-2, was implicated in the short term stage. Here we uncover a novel role for the CNG channel subunit, CNG-3, in short term adaptation. We demonstrate that CNG-3 is required in the AWC for adaptation to short (thirty minute) exposures of odor, and contains a candidate PKG phosphorylation site required to tune odor sensitivity. We also provide in vivo data suggesting that CNG-3 forms a complex with both TAX-2 and TAX-4 CNG channel subunits in AWC. Finally, we examine the physiology of different CNG channel subunit combinations.

Theory of nodal s ±-wave pairing symmetry in the Pu-based 115 superconductor family

DOE PAGES

Das, Tanmoy; Zhu, Jian -Xin; Graf, Matthias J.

2015-02-27

The spin-fluctuation mechanism of superconductivity usually results in the presence of gapless or nodal quasiparticle states in the excitation spectrum. Nodal quasiparticle states are well established in copper-oxide, and heavy-fermion superconductors, but not in iron-based superconductors. Here, we study the pairing symmetry and mechanism of a new class of plutonium-based high-T c superconductors and predict the presence of a nodal s⁺⁻ wave pairing symmetry in this family. Starting from a density-functional theory (DFT) based electronic structure calculation we predict several three-dimensional (3D) Fermi surfaces in this 115 superconductor family. We identify the dominant Fermi surface “hot-spots” in the inter-band scatteringmore » channel, which are aligned along the wavevector Q = (π, π, π), where degeneracy could induce sign-reversal of the pairing symmetry. Our calculation demonstrates that the s⁺⁻ wave pairing strength is stronger than the previously thought d-wave pairing; and more importantly, this pairing state allows for the existence of nodal quasiparticles. Finally, we predict the shape of the momentum- and energy-dependent magnetic resonance spectrum for the identification of this pairing symmetry.« less

Direct uptake of soil nitrogen by mosses.

PubMed

Ayres, Edward; van der Wal, René; Sommerkorn, Martin; Bardgett, Richard D

2006-06-22

Mosses are one of the most diverse and widespread groups of plants and often form the dominant vegetation in montane, boreal and arctic ecosystems. However, unlike higher plants, mosses lack developed root and vascular systems, which is thought to limit their access to soil nutrients. Here, we test the ability of two physiologically and taxonomically distinct moss species to take up soil- and wet deposition-derived nitrogen (N) in natural intact turfs using stable isotopic techniques (15N). Both species exhibited increased concentrations of shoot 15N when exposed to either soil- or wet deposition-derived 15N, demonstrating conclusively and for the first time, that mosses derive N from the soil. Given the broad physiological and taxonomic differences between these moss species, we suggest soil N uptake may be common among mosses, although further studies are required to test this prediction. Soil N uptake by moss species may allow them to compete for soil N in a wide range of ecosystems. Moreover, since many terrestrial ecosystems are N limited, soil N uptake by mosses may have implications for plant community structure and nutrient cycling. Finally, soil N uptake may place some moss species at greater risk from N pollution than previously appreciated.

Polygyny, mate-guarding, and posthumous fertilization as alternative male mating strategies

PubMed Central

Zamudio, Kelly R.; Sinervo, Barry

2000-01-01

Alternative male mating strategies within populations are thought to be evolutionarily stable because different behaviors allow each male type to successfully gain access to females. Although alternative male strategies are widespread among animals, quantitative evidence for the success of discrete male strategies is available for only a few systems. We use nuclear microsatellites to estimate the paternity rates of three male lizard strategies previously modeled as a rock-paper-scissors game. Each strategy has strengths that allow it to outcompete one morph, and weaknesses that leave it vulnerable to the strategy of another. Blue-throated males mate-guard their females and avoid cuckoldry by yellow-throated “sneaker” males, but mate-guarding is ineffective against aggressive orange-throated neighbors. The ultradominant orange-throated males are highly polygynous and maintain large territories; they overpower blue-throated neighbors and cosire offspring with their females, but are often cuckolded by yellow-throated males. Finally, yellow-throated sneaker males sire offspring via secretive copulations and often share paternity of offspring within a female's clutch. Sneaker males sire more offspring posthumously, indicating that sperm competition may be an important component of their strategy. PMID:11106369

Proper Motions and Structural Parameters of the Galactic Globular Cluster M71

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cadelano, M.; Dalessandro, E.; Ferraro, F. R.

2017-02-20

By exploiting two ACS/ HST data sets separated by a temporal baseline of ∼7 years, we have determined the relative stellar proper motions (PMs; providing membership) and the absolute PM of the Galactic globular cluster M71. The absolute PM has been used to reconstruct the cluster orbit within a Galactic, three-component, axisymmetric potential. M71 turns out to be in a low-latitude disk-like orbit inside the Galactic disk, further supporting the scenario in which it lost a significant fraction of its initial mass. Since large differential reddening is known to affect this system, we took advantage of near-infrared, ground-based observations tomore » re-determine the cluster center and density profile from direct star counts. The new structural parameters turn out to be significantly different from the ones quoted in the literature. In particular, M71 has a core and a half-mass radii almost 50% larger than previously thought. Finally, we estimate that the initial mass of M71 was likely one order of magnitude larger than its current value, thus helping to solve the discrepancy with the observed number of X-ray sources.« less

Chronic pancreatitis.

PubMed

Yang, Dennis; Forsmark, Chris E

2017-09-01

Summarize key clinical advances in chronic pancreatitis reported in 2016. Early diagnosis of chronic pancreatitis remains elusive. Recent studies suggest that endoscopic ultrasound may be less accurate than previously thought and new MRI techniques may be helpful. Genetic predisposition may independently affect the clinical course of chronic pancreatitis and the risk for pancreatic cancer. Cigarette smoking may have a greater negative impact on chronic pancreatitis than previously thought and moderate alcohol consumption may be protective. A multidisciplinary approach is necessary for the treatment of type 3 diabetes and nutritional deficiencies in chronic pancreatitis. Although endoscopic therapy remains a reasonable first-line option in treating chronic pancreatitis and its complications, early surgical intervention may be indicated for pain in select patients. Newer endoscopic ultrasound and MRI techniques are being evaluated to help with the early diagnosis of chronic pancreatitis. Both genetic predisposition and cigarette smoking are increasingly recognized as having a major impact in the course of the disease and the risk for pancreatic cancer. Endoscopic therapy is well tolerated and effective for the treatment of chronic pancreatitis and its complications although an early surgical approach for pain may be associated with improved clinical outcomes.

Influence of Caloric Vestibular Stimulation on Body Experience in Healthy Humans

PubMed Central

Schönherr, Andreas; May, Christian Albrecht

2016-01-01

The vestibular system has more connections with and influence on higher cortical centers than previously thought. These interactions with higher cortical centers and the phenomena that they elicit require a structural intact cerebral cortex. To date, little is known about the role and influence of the vestibular system on one’s body experience. In this study we show that caloric vestibular stimulation (CVS) in healthy participants has an effect on the perceptive component of one’s body experience. After CVS all participants showed a statistically significant difference of thigh width estimation. In contrast to previous studies, which demonstrated an influence of CVS on higher cortical centers with an intact cerebral cortex both the cognitive and affective component of body experience were not effected by the CVS. Our results demonstrate the influence of the vestibular system on body perception and emphasize its role in modulating different perceptive-qualities which contributes to our body experience. We found that CVS has a limited influence on one’s conscious state, thought process and higher cortical functions. PMID:27013995

Leishmania donovani: expression and characterization of Escherichia coli-expressed recombinant chitinase LdCHT1.

PubMed

Razek-Desouky, A; Specht, C A; Soong, L; Vinetz, J M

2001-12-01

Leishmania parasites produce chitinase activity (EC. 3.2.1.14) thought to be important in parasite-sandfly interactions and transmission of the parasite to the vertebrate host. Previous observations have suggested that parasite chitinases are involved in degradation of the sandfly peritrophic matrix and the chitinous layer of the cardiac valve cuticle. This chitinase activity is thought to produce an incompetent pharyngeal valve sphincter and a route of egress that allow Leishmania promastigotes to be regurgitated into the site of blood feeding. In the studies reported here, enzymatically active L. donovani chitinase LdCHT1 was expressed as a thioredoxin fusion protein in Escherichia coli strain AD494 (DE3). Recombinant LdCHT1 had a predominantly endochitinase activity, in contrast to previous reports of both exo- and endochitinase activities in axenic culture supernatants of diverse Leishmania spp. promastigotes. The predominant endochitinase activity of recombinant LdCHT1 is consistent with the presumed function of the enzyme in disrupting chitinous structures in the sandfly digestive system to allow transmission. Copyright 2001 Elsevier Science (USA).

Food cravings in everyday life: An EMA study on snack-related thoughts, cravings, and consumption.

PubMed

Richard, Anna; Meule, Adrian; Reichenberger, Julia; Blechert, Jens

2017-06-01

Food craving refers to an intense desire to consume a specific food and is regularly experienced by the majority of individuals. Yet, there are interindividual differences in the frequency and intensity of food craving experiences, which is often referred to as trait food craving. The characteristics and consequences of trait and state food craving have mainly been investigated in questionnaire-based and laboratory studies, which may not reflect individuals' behavior in daily life. In the present study, sixty-one participants completed the Food Cravings Questionnaire-Trait-reduced (FCQ-T-r) as measure of trait food craving, followed by seven days of Ecological Momentary Assessment (EMA), during which they reported snack-related thoughts, craving intensity, and snack consumption at five times per day. Results showed that 86 percent of reported snacks were high-caloric, with chocolate-containing foods being the most often reported snacks. Individuals with high FCQ-T-r scores (high trait food cravers, HCs) thought more often about high-calorie than low-calorie snacks whereas no differences were found in individuals with low FCQ-T-r scores (low trait food cravers, LCs). Further, the relationship between craving intensity and snack-related thoughts was stronger in HCs than in LCs. Higher craving intensity was associated with more consumption of snacks and again this relationship was stronger in HCs than in LCs. Finally, more snack-related thoughts were related to more frequent consumption of snacks, independent of trait food craving. Thus, HCs are more prone to think about high-calorie snacks in their daily lives and to consume more snack foods when they experience intense cravings, which might be indicative of a heightened responding towards high-calorie foods. Thus, trait-level differences as well as snack-related thoughts should be targeted in dietary interventions. Copyright © 2017 Elsevier Ltd. All rights reserved.

Children's thoughts on the social exclusion of peers with intellectual or learning disabilities.

PubMed

Nowicki, E A; Brown, J; Stepien, M

2014-04-01

Previous research has shown that children with intellectual or learning disabilities are at risk for social exclusion by their peers but little is known of children's views on this topic. In this study, we used concept mapping to investigate elementary school children's thoughts on why they believe their peers with intellectual or learning disabilities are sometimes socially excluded at school. Participants were 49 grade five and six children who attended inclusive classrooms. Interviews were digitally recorded and transcribed. We extracted 49 unique statements from the transcribed data, and then invited participants to sort the statements into meaningful categories. Sorted data were entered into matrices, which were summed and analysed with multi-dimensional scaling and cluster analysis. A four-cluster solution provided the best conceptual fit for the data. Clusters reflected themes on (1) the thoughts and actions of other children; (2) differences in learning ability and resource allocation; (3) affect, physical characteristics and schooling; and (4) negative thoughts and behaviours. The overarching reason for social exclusion focused on differences between children with and without disabilities. This study also provided evidence that children are effective, reliable and competent participants in concept mapping. Educational and research implications are discussed. © 2013 The Authors. Journal of Intellectual Disability Research © 2013 John Wiley & Sons Ltd, MENCAP & IASSIDD.

Identification of viral and non-viral reverse transcribing elements in pineapple (Ananas comosus), including members of two new badnavirus species.

PubMed

Gambley, C F; Geering, A D W; Steele, V; Thomas, J E

2008-01-01

A previously published partial sequence of pineapple bacilliform virus was shown to be from a retrotransposon (family Metaviridae) and not from a badnavirus as previously thought. Two newly discovered sequence groups isolated from pineapple were associated with bacilliform virions and were transmitted by mealybugs. Phylogenetic analyses indicated that they were members of new badnavirus species. A third caulimovirid sequence was also amplified from pineapple, but available evidence suggests that this DNA is not encapsidated, but more likely derived from an endogenous virus.

Earthquake studies reveal the magmatic plumbing system of the Katmai volcanoes

USGS Publications Warehouse

Thurber, Clifford; Murphy, Rachel; Prejean, Stephanie G.; Haney, Matthew M.; Bennington, Ninfa; Powell, Lee; Paskievitch, John F.

2012-01-01

Our main finding is that there is not a single large anomalous zone centered beneath Katmai Pass; rather there are several separate anomalous zones, one each beneath Katmai, Trident-Novarupta, and Martin-Mageik. Furthermore, the earthquakes are tightly clustered beneath the various volcanic centers, and are found to be systematically deeper than previously thought. Linear trends of earthquakes are also revealed, similar to features observed at other volcanoes, possibly outlining previously unidentified fault structures or indicating the path of migrating magma or magmatic fluids and gases.

[Philosophy, psychiatry and psychoanalysis: the case of Nietzsche].

PubMed

Wolf, M A

1995-05-01

In this work dedicated to Frederic Nietzsche, we were first interested by the philosopher's personal psychopathology. Biographic and personality factors, the physical and moral pain, the mood variations, hypersensitivity, solitude and finally megalomanic traits have probably contributed to the development of his thought. Nietzsche gave personal interpretations of his own suffering. Freud himself recognized the organic component of the philosopher's illness. We reviewed the different symptoms in favor of a progressive general paresis. Philologist and moralist, Nietzsche was also a "psychologist". His intuitions in this area often preceded and prepared those of Freud. The relationship is surprising on certain points such as love and sexuality, the unconscious, the interpretation of dreams. We wish to remind readers that a prepsychoanalytic stream of thought, at the end of the 19th century, preceded the teaching now ascribed to Freud and his followers.

Positive and negative eating expectancies in disordered eating among women and men.

PubMed

Hayaki, Jumi; Free, Sarah

2016-08-01

Deficits in emotion regulation are known to characterize disordered eating patterns including binge eating, purging, and dietary restraint, though much of this work has been conducted exclusively on women. Eating expectancies, or expectations regarding reinforcement from food and eating, constitute one cognitive mechanism that is thought to serve as a proximal influence on eating behavior. Previous research shows that eating to manage negative affect (a negative eating expectancy) is associated with eating pathology in women, but less is known about eating as a reward or for pleasure (a positive eating expectancy). In addition, no prior work has examined eating expectancies among men. This study examines the role of emotion regulation and eating expectancies on disordered eating in women and men. Participants were 121 female and 80 male undergraduates who completed self-report measures of emotion regulation, eating expectancies, and disordered eating. In women, body mass index (BMI), emotion regulation, and eating to manage negative affect directly predicted disordered eating in the final multivariate model, whereas eating for pleasure or reward was inversely associated with disordered eating. However, in men, emotion regulation predicted disordered eating, but not when eating expectancies were added to the model. In the final model, only BMI and eating to manage negative affect contributed significantly to the variance in disordered eating. These findings suggest that some correlates of eating pathology, particularly eating expectancies, may vary by gender. Future research should continue to examine gender differences in the explanatory mechanisms underlying disordered eating. Copyright © 2016 Elsevier Ltd. All rights reserved.

Distribution and abundance of cetaceans in the north-central and western Gulf of Mexico. Final report. Volume 3. Appendix A

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davis, R.W.; Fargion, G.S.

1996-05-24

The purpose of the study was to determine the distribution and abundance of cetaceans in areas potentially affected by future oil and gas activities along the continental slope of the north-central and western Gulf of Mexico. This 3.75 year project commenced 1 October 1991 and finished 15 July 1995. The study area was bounded by the Florida-Alabama border, the Texas-Mexico border, and the 100 m and 2,000 m isobaths. Cetacean distribution and abundance were determined from seasonal aerial and shipboard visual surveys and shipboard acoustic surveys. In addition, hydrographic data were collected in situ and by satellite remote sensing tomore » characterize cetacean habitat. Finally, tagging and tracking of sperm whales using satellite telemetry was attempted. Appendix A contains: the cetacean, trutle, and bird sighting data from all shipboard and aerial visual surveys; contact data from the shipboard acoustic survey; and the cetacean environmental profiles. Cetaceans were observed throughout the study area during all four seasons. Nineteen species were identified, including two species (melon-headed whales and Fraser`s dolphins) previously thought to be rare in the Gulf. Pantropical spotted dolphins, bottlenose dolphins, clymene dolphins, striped dolphins, Atlantic spotted dolphins, and melon-headed whales were the most common small cetaceans and the sperm whale was the most common large cetacean. The mean annual abundance for all cetaceans was estimated to be 19,198. Although the study area had complex and dynamic oceanography, bottom depth was the only environmental variable which correlated to cetacean distribution.« less

On the apparent positions of T Tauri stars in the H-R diagram

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kenyon, S.J.; Hartmann, L.W.

1990-01-01

The spread in apparent luminosities of T Tauri stars caused by occultation and emission from protostellar disks is investigated. A random distribution of disk inclination angles, coupled with a plausible range of accretion rates, introduces a significant scatter in apparent luminosities for intrinsically identical stars. The observed dispersion of luminosities for K7-M1 Hayashi track stars thought to have disks in Taurus-Auriga is similar to predictions of the simple accretion disk model, which suggets that age determinations form many pre-main-sequence stars are uncertain. The results also suggest that Stahler's birthline for convective track pre-main-sequence stars may be located at slightly lowermore » luminosities than previously thought. 38 refs.« less

From Shattered Assumptions to Weakened Worldviews: Trauma Symptoms Signal Anxiety Buffer Disruption.

PubMed

Edmondson, Donald; Chaudoir, Stephenie R; Mills, Mary Alice; Park, Crystal L; Holub, Julie; Bartkowiak, Jennifer M

2011-01-01

The fundamental assertion of worldview-based models of posttraumatic stress disorder is that trauma symptoms result when traumatic experiences cannot be readily assimilated into previously held worldviews. In two studies, we test the anxiety buffer disruption hypothesis, which states that trauma symptoms result from the disruption of normal death anxiety-buffering functions of worldview. In Study 1, participants with trauma symptoms greater than the cutoff for PTSD evinced greater death-thought accessibility than those with sub-clinical or negligible symptoms after a reminder of death. In Study 2, participants with clinically significant trauma symptoms showed no evidence of worldview defense though death-thoughts were accessible. These results support the anxiety buffer disruption hypothesis, and suggest an entirely new approach to experimental PTSD research.

A thought construction of working perpetuum mobile of the second kind

NASA Astrophysics Data System (ADS)

Čápek, V.; Bok, J.

1999-12-01

The previously published model of the isothermal Maxwell demon as one of models of open quantum systems endowed with the faculty of selforganization is reconstructed here. It describes an open quantum system interacting with a single thermodynamic bath but otherwise not aided from outside. Its activity is given by the standard linear Liouville equation for the system and bath. Owing to its selforganization property, the model then yields cyclic conversion of heat from the bath into mechanical work without compensation. Hence, it provides an explicit thought construction of perpetuum mobile of the second kind, contradicting thus the Thomson formulation of the second law of thermodynamics. No approximation is involved as a special scaling procedure is used which makes the employed kinetic equations exact.

Ultraconserved regions encoding ncRNAs are altered in human leukemias and carcinomas.

PubMed

Calin, George A; Liu, Chang-gong; Ferracin, Manuela; Hyslop, Terry; Spizzo, Riccardo; Sevignani, Cinzia; Fabbri, Muller; Cimmino, Amelia; Lee, Eun Joo; Wojcik, Sylwia E; Shimizu, Masayoshi; Tili, Esmerina; Rossi, Simona; Taccioli, Cristian; Pichiorri, Flavia; Liu, Xiuping; Zupo, Simona; Herlea, Vlad; Gramantieri, Laura; Lanza, Giovanni; Alder, Hansjuerg; Rassenti, Laura; Volinia, Stefano; Schmittgen, Thomas D; Kipps, Thomas J; Negrini, Massimo; Croce, Carlo M

2007-09-01

Noncoding RNA (ncRNA) transcripts are thought to be involved in human tumorigenesis. We report that a large fraction of genomic ultraconserved regions (UCRs) encode a particular set of ncRNAs whose expression is altered in human cancers. Genome-wide profiling revealed that UCRs have distinct signatures in human leukemias and carcinomas. UCRs are frequently located at fragile sites and genomic regions involved in cancers. We identified certain UCRs whose expression may be regulated by microRNAs abnormally expressed in human chronic lymphocytic leukemia, and we proved that the inhibition of an overexpressed UCR induces apoptosis in colon cancer cells. Our findings argue that ncRNAs and interaction between noncoding genes are involved in tumorigenesis to a greater extent than previously thought.

Measurement of radiative proton capture on 18F and implications for oxygen-neon novae reexamined

NASA Astrophysics Data System (ADS)

Akers, C.; Laird, A. M.; Fulton, B. R.; Ruiz, C.; Bardayan, D. W.; Buchmann, L.; Christian, G.; Davids, B.; Erikson, L.; Fallis, J.; Hager, U.; Hutcheon, D.; Martin, L.; Murphy, A. St. J.; Nelson, K.; Ottewell, D.; Rojas, A.; Spyrou, A.

2016-12-01

Background: The rate of the 18F(p ,γ )19Ne reaction affects the final abundance of the radioisotope 18F ejected from novae. This nucleus is important as its abundance is thought to significantly influence the first-stage 511-keV and continuum γ -ray emission in the aftermath of novae. No successful measurement of this reaction existed prior to this work, and the rate used in stellar models had been calculated based on incomplete information from contributing resonances. Purpose: Of the two resonances thought to provide a significant contribution to the astrophysical reaction rate, located at Ec .m .=330 and 665 keV, the former has a radiative width estimated from the assumed analog state in the mirror nucleus, 19F, while the latter resonance does not have an analog state assignment, resulting in an arbitrary radiative width being assumed. As such, a direct measurement was needed to establish what role this resonance plays in the destruction of 18F at nova temperatures. This paper extends and takes the place of a previous Letter which reported the strength of the Ec .m .=665 keV resonance. Method: The DRAGON recoil separator was used to directly measure the strength of the important 665-keV resonance in this reaction, in inverse kinematics, by observing 19Ne reaction products. A radioactive 18F beam was provided by the ISAC facility at TRIUMF. R -matrix calculations were subsequently used to evaluate the significance of the results at astrophysical energies. Results: We report the direct measurement of the 18F(p ,γ )19Ne reaction with the reevaluation of several detector efficiencies and the use of an updated 19Ne level scheme in the reaction rate analysis. The strength of the 665-keV resonance (Ex=7.076 MeV) is found to be an order of magnitude weaker than currently assumed in nova models. An improved analysis of the previously reported data is presented here, resulting in a slightly different value for the resonance strength. These small changes, however, do not alter the primary conclusions. Conclusions: Reaction rate calculations definitively show that the 665-keV resonance plays no significant role in the destruction of 18F at nova temperatures.

Requiem for a Data Base System.

DTIC Science & Technology

1979-01-18

were defined -- - 2) the final syntax and semantics of QUEL were defined 3) protection was figured out 14) EQUEL was designed 5) concurrency control and...features which were not thought about in the initial design (such as concurrency control and recovery) and began worrying about distributed data...made in progress rather than on eventual corrections. Some attention is also given to the role of structured design in a data base system implementation

Special challenges in the conservation of fishes and aquatic environments of South America.

PubMed

Costa, M F; Barletta, M

2016-07-01

In South America, the conservation of natural resources, particularly in relation to water and aquatic fauna, is an often-discussed issue. Unfortunately, there is still a large gap between thoughts and action. Scientists from different countries of the continent have however, produced a significant body of literature that should finally become the basis of emerging managerial models. © 2016 The Fisheries Society of the British Isles.

NASA Hazard Analysis Process

NASA Technical Reports Server (NTRS)

Deckert, George

2010-01-01

This viewgraph presentation reviews The NASA Hazard Analysis process. The contents include: 1) Significant Incidents and Close Calls in Human Spaceflight; 2) Subsystem Safety Engineering Through the Project Life Cycle; 3) The Risk Informed Design Process; 4) Types of NASA Hazard Analysis; 5) Preliminary Hazard Analysis (PHA); 6) Hazard Analysis Process; 7) Identify Hazardous Conditions; 8) Consider All Interfaces; 9) Work a Preliminary Hazard List; 10) NASA Generic Hazards List; and 11) Final Thoughts

Cognitive Styles and the Social Order. Final Report, Part II. O.E.O. Study B00-5135, "Thought, Race, and Opportunity."

ERIC Educational Resources Information Center

TenHouten, Warren D.

This report presents data developed for testing the theory that there are social processes which result in differing cognitive styles for subdominant and dominant social groups. The results of surveys of black and white persons in an urban area, of white rural farmers, and Hopi Indians are presented. The research attempts to integrate data and…

Soviet Assessments of North American Air Defense

DTIC Science & Technology

1986-06-01

whether they represented misunderstandings or errors on the Soviet part, or unique Soviet perspectives and biases. Finally, articles on Soviet strategy...and what reactions do these assessments prompt? First, most articles on U.S. continental air defenses were found in the journal of the Air Defense...Soviet assessments of U.S. air defense control systems with articles in Military Thought. Some of these themes are: - The importance of centralized

Medical students' attitudes to caring for a young infant--can parenting a doll influence these beliefs?

PubMed

Bath, L E; Cunningham, S; McIntosh, N

2000-12-01

To investigate whether attitudes to parenting were altered in final year medical students following a period spent caring for a simulated infant. Seventy medical students during their paediatric attachment in the final year completed a questionnaire regarding personal childcare attitudes. Students attached to a teaching hospital were allocated a 24 hour time period to care for "Baby Think It Over" (BTIO), a computerised doll that simulates a 6 week old infant and records care given. The students then completed a second questionnaire assessing the impact of the experience. Forty nine per cent of students thought their advice regarding sick children was less valid than if they had their own children; 96% of students believed their approach to parents caring for young infants could be improved by caring for a 6 week old infant. All the students felt their lifestyle would be affected. Following the BTIO care period, 79% considered the experience straightforward, with 35% expressing a little more empathy and 15% a lot more empathy for parents as a result. Thoughts regarding impact on lifestyle were unaltered. Caring for BTIO, however, was not considered to be a realistic experience and overall not particularly useful. Simulated infants are of only limited value in increasing medical student understanding of parental concerns.

Racial Healthcare Disparities: A Social Psychological Analysis

PubMed Central

Penner, Louis A.; Hagiwara, Nao; Eggly, Susan; Gaertner, Samuel L.; Albrecht, Terrance L.; Dovidio, John F.

2014-01-01

Around the world, members of racial/ethnic minority groups typically experience poorer health than members of racial/ethnic majority groups. The core premise of this article is that thoughts, feelings, and behaviors related to race and ethnicity play a critical role in healthcare disparities. Social psychological theories of the origins and consequences of these thoughts, feelings, and behaviors offer critical insights into the processes responsible for these disparities and suggest interventions to address them. We present a multilevel model that explains how societal, intrapersonal, and interpersonal factors can influence ethnic/racial health disparities. We focus our literature review, including our own research, and conceptual analysis at the intrapersonal (the race-related thoughts and feelings of minority patients and non-minority physicians) and interpersonal levels (intergroup processes that affect medical interactions between minority patients and non-minority physicians). At both levels of analysis, we use theories of social categorization, social identity, contemporary forms of racial bias, stereotype activation, stigma, and other social psychological processes to identify and understand potential causes and processes of health and healthcare disparities. In the final section, we identify theory-based interventions that might reduce ethnic/racial disparities in health and healthcare. PMID:25197206

Colonic stem cell data are consistent with the immortal model of stem cell division under non-random strand segregation.

PubMed

Walters, K

2009-06-01

Colonic stem cells are thought to reside towards the base of crypts of the colon, but their numbers and proliferation mechanisms are not well characterized. A defining property of stem cells is that they are able to divide asymmetrically, but it is not known whether they always divide asymmetrically (immortal model) or whether there are occasional symmetrical divisions (stochastic model). By measuring diversity of methylation patterns in colon crypt samples, a recent study found evidence in favour of the stochastic model, assuming random segregation of stem cell DNA strands during cell division. Here, the effect of preferential segregation of the template strand is considered to be consistent with the 'immortal strand hypothesis', and explore the effect on conclusions of previously published results. For a sample of crypts, it is shown how, under the immortal model, to calculate mean and variance of the number of unique methylation patterns allowing for non-random strand segregation and compare them with those observed. The calculated mean and variance are consistent with an immortal model that incorporates non-random strand segregation for a range of stem cell numbers and levels of preferential strand segregation. Allowing for preferential strand segregation considerably alters previously published conclusions relating to stem cell numbers and turnover mechanisms. Evidence in favour of the stochastic model may not be as strong as previously thought.

Facial Expression Recognition: Can Preschoolers with Cochlear Implants and Hearing Aids Catch It?

ERIC Educational Resources Information Center

Wang, Yifang; Su, Yanjie; Fang, Ping; Zhou, Qingxia

2011-01-01

Tager-Flusberg and Sullivan (2000) presented a cognitive model of theory of mind (ToM), in which they thought ToM included two components--a social-perceptual component and a social-cognitive component. Facial expression recognition (FER) is an ability tapping the social-perceptual component. Previous findings suggested that normal hearing…

An Empirical Approach to the St. Petersburg Paradox

ERIC Educational Resources Information Center

Klyve, Dominic; Lauren, Anna

2011-01-01

The St. Petersburg game is a probabilistic thought experiment. It describes a game which seems to have infinite expected value, but which no reasonable person could be expected to pay much to play. Previous empirical work has centered around trying to find the most likely payoff that would result from playing the game n times. In this paper, we…

Paradigm Lost: The Human Chromosome Story.

ERIC Educational Resources Information Center

Unger, Lawrence; Blystone, Robert V.

1996-01-01

Discusses whether the discovery in 1956 that humans have a chromosome number of 46, as opposed to 47 or 48 as previously thought, fits into a paradigm shift of the Kuhnian type. Concludes that Kuhn probably would not have considered the chromosome number shift to be large enough to be a focus for one of his paradigms. (AIM)

Examining Thought Processes to Understand the Impact of Water Conservation Messages on Attitude

ERIC Educational Resources Information Center

Rumble, Joy N.; Lamm, Alexa J.; Martin, Emmett T.; Warner, Laura A.

2017-01-01

Water availability issues have plagued many regions around the world and is viewed as the top issue facing the world. As a result, encouraging water conservation has become a priority for agricultural communicators. Previous research suggests strategically framed messages can impact attitudes about water conservation, but whether this change is a…

Activation of mouse and human Peroxisome Proliferator-Activated Receptor-alpha (PPARa) by Perfluoroalkyl Acids(PFAAs): Further investigation of C4-C12 compounds.

EPA Science Inventory

Perfluorinated alkyl acids (PFAAs) are manufactured surfactants found globally in the environment and in tissues of humans and wildlife. Several PFAAs adversely affect rodents and activation of PPARa is thought to be their mode of action. Our previous study demonstrated that some...

Personality Correlates of People Who Have Attempted Suicide and Those Who Have Seriously Considered It.

ERIC Educational Resources Information Center

Kaminsky, Sarah; Chrisler, Joan C.

Depression and low self-esteem are commonly considered to be at the root of suicidal ideation. Previous research has examined the correlations between a lack of purpose in life and depression, low self-esteem, substance abuse and suicidal thoughts. This study investigated personality differences among student groups who have attempted suicide.…

Non-Traditional Tradition in the Heartland: Women's Choices in the Nebraska Gubernatorial Campaign.

ERIC Educational Resources Information Center

Hardy-Short, Dayle C.

Although the Nebraska gubernatorial race was the first statewide race in which both candidates were women, women's issues were seldom raised--even though both candidates thought the women's movement had helped to make their previous campaigns successful. Because each candidate opposed abortion, neither was endorsed by any of the major women's…

A Qualitative Study of the Health-Related Quality of Life of Disabled Children

ERIC Educational Resources Information Center

Young, Bridget; Rice, Helen; Dixon-Woods, Mary; Colver, Allan F.; Parkinson, Kathryn N.

2007-01-01

This qualitative study investigated what disabled children thought most important in their lives and examined how well their priorities are represented in KIDSCREEN, a generic health-related quality of life (HRQoL) instrument. Participants were a subgroup of families who had previously taken part in a study of quality of life and participation in…

Child Development and Structural Variation in the Human Genome

ERIC Educational Resources Information Center

Zhang, Ying; Haraksingh, Rajini; Grubert, Fabian; Abyzov, Alexej; Gerstein, Mark; Weissman, Sherman; Urban, Alexander E.

2013-01-01

Structural variation of the human genome sequence is the insertion, deletion, or rearrangement of stretches of DNA sequence sized from around 1,000 to millions of base pairs. Over the past few years, structural variation has been shown to be far more common in human genomes than previously thought. Very little is currently known about the effects…

Functionality of a maize chitinase potentially involved in ear rot pathogen resistance

USDA-ARS?s Scientific Manuscript database

Chitinases are thought to play a role in plant resistance to fungal pathogens by degrading the fungal cell wall, but few have been investigated to any great extent. The gene for a maize (Zea mays) chitinase “chitinase 2” previously reported to be induced by two ear rot pathogens in infected tissues ...

Patterns of hybridization among cutthroat trout and rainbow trout in northern Rocky Mountain streams

Treesearch

Kevin S. McKelvey; Michael K. Young; Taylor M. Wilcox; Daniel M. Bingham; Kristine L. Pilgrim; Michael K. Schwartz

2016-01-01

Introgressive hybridization between native and introduced species is a growing conservation concern. For native cutthroat trout and introduced rainbow trout in western North America, this process is thought to lead to the formation of hybrid swarms and the loss of monophyletic evolutionary lineages. Previous studies of this phenomenon, however, indicated that...

Brain-Based Aspects of Cognitive Learning Approaches in Second Language Learning

ERIC Educational Resources Information Center

Moghaddam, Alireza Navid; Araghi, Seyed Mahdi

2013-01-01

Language learning process is one of the complicated behaviors of human beings which has called many scholars and experts' attention especially after the middle of last century by the advent of cognitive psychology that later on we see its implication to education. Unlike previous thought of schools, cognitive psychology deals with the way in which…

Conflicting Pathways to Participation in the FL Classroom: L2 Speech Production vs. L2 Thought Processes

ERIC Educational Resources Information Center

Bernales, Carolina

2016-01-01

Previous research on foreign language classroom participation has shown that oral production has a privileged status compared to less salient forms of participation, such as mental involvement and engagement in class activities. This mixed-methods study presents an alternative look at classroom participation by investigating the relationship…

Sulfate Addition Increases Methylmercury Production in an Experimental Wetland

Treesearch

Jeff D. Jeremiason; Daniel R. Engstrom; Edward B. Swain; Edward A. Nater; Brian M. Johnson; James E. Almendinger; Bruce A. Monson; Randy K. Kolka

2006-01-01

Atmospheric mercury is the dominant Hg source to fish in northern Minnesota and elsewhere. However, atmospherically derived Hg must be methylated prior to accumulating in fish. Sulfate-reducing bacteria are thought to be the primary methylators of Hg in the environment. Previous laboratory and field mesocosm studies have demonstrated an increase in methylmercury (MeHg...

Serologic Evidence of Powassan Virus Infection in Patients with Suspected Lyme Disease1.

PubMed

Frost, Holly M; Schotthoefer, Anna M; Thomm, Angela M; Dupuis, Alan P; Kehl, Sue C; Kramer, Laura D; Fritsche, Thomas R; Harrington, Yvette A; Knox, Konstance K

2017-08-01

Powassan virus (POWV) lineage II is an emerging tickborne flavivirus with an unknown seroprevalence in humans. In a Lyme disease-endemic area, we examined the seroreactivity to POWV in 2 patient cohorts and described the clinical features of the POWV-seroreactive patients. POWV disease might be less neuroinvasive than previously thought.

Serologic Evidence of Powassan Virus Infection in Patients with Suspected Lyme Disease1

PubMed Central

Schotthoefer, Anna M.; Thomm, Angela M.; Dupuis, Alan P.; Kehl, Sue C.; Kramer, Laura D.; Fritsche, Thomas R.; Harrington, Yvette A.; Knox, Konstance K.

2017-01-01

Powassan virus (POWV) lineage II is an emerging tickborne flavivirus with an unknown seroprevalence in humans. In a Lyme disease–endemic area, we examined the seroreactivity to POWV in 2 patient cohorts and described the clinical features of the POWV-seroreactive patients. POWV disease might be less neuroinvasive than previously thought. PMID:28726610

Hand Path Priming in Manual Obstacle Avoidance: Rapid Decay of Dorsal Stream Information

ERIC Educational Resources Information Center

Jax, Steven A.; Rosenbaum, David A.

2009-01-01

The dorsal, action-related, visual stream has been thought to have little or no memory. This hypothesis has seemed credible because functions related to the dorsal stream have been generally unsusceptible to priming from previous experience. Tests of this claim have yielded inconsistent results, however. We argue that these inconsistencies may be…

Brief Report: Systematic Review of Rett Syndrome in Males

ERIC Educational Resources Information Center

Reichow, Brian; George-Puskar, Annie; Lutz, Tara; Smith, Isaac C.; Volkmar, Fred R.

2015-01-01

Rett syndrome (RTT) is a neurogenetic disorder in which a period of typical development is followed by loss of previously acquired skills. Once thought to occur exclusively in females, increasing numbers of male cases of RTT have been reported. This systematic review included 36 articles describing 57 cases of RTT in males. Mutations of the MECP2…

University Teachers' Perceptions of Online Informal Learning of English (OILE)

ERIC Educational Resources Information Center

Toffoli, Denyze; Sockett, Geoff

2015-01-01

Online Informal Learning of English (OILE) involves the many different types of language practices that non-specialist EFL students of English are involved in on the Internet. This article reviews previous studies in the area and summarises the specific outcomes that OILE is thought to produce. It then presents an analysis of a survey of teachers'…

The Effect of Population Growth upon the Quantity of Education Children Receive.

ERIC Educational Resources Information Center

Simon, Julian L.; Pilarski, Adam M.

1979-01-01

There is indeed some negative effect of population growth on the amount of education in developing nations, but the effect is less severe than has been thought. This finding is in sharp contrast to previous conclusions drawn from similar cross-national data. Available from Review of Economics and Statistics, M-8 Littauer Center, Cambridge, MA…

Occurrence of the Rayed Creekshell, Anodontoides Radzatus, in the Mississippi River Basin: Implications For Conservation and Biogeography

Treesearch

Wendell R. Haag; Melvin L. Warren; Keith Wright; Larry Shaffer

2002-01-01

We document the occurrence of the rayed creekshell (Anodontoides radiatus Conrad), a freshwater mussel (Unionidae), at eight sites in the upper Yazoo River drainage (lower Mississippi River Basin) in northern Mississippi. Previously, A. radiatus was thought to be restricted to Gulf Coast drainages as far west only as the...

Educational Technology Program. Quarterly Technical Summary, 1 December 1970 through 28 February 1971.

ERIC Educational Resources Information Center

Frick, Frederick C.

The decision to employ direct rather than diffraction recording in the Lincoln Training System (LTS) is reported. This resulted from the findings that direct recording was practical at higher densities than previously thought possible and that rapid access to a number of fiche would compensate for the limited number of frames per fiche realized…

Altered Cingulate Sub-Region Activation Accounts for Task-Related Dissociation in ERN Amplitude as a Function of Obsessive-Compulsive Symptoms

ERIC Educational Resources Information Center

Cavanagh, James F.; Grundler, Theo O. J.; Frank, Michael J.; Allen, John J. B.

2010-01-01

Larger error-related negativities (ERNs) have been consistently found in obsessive-compulsive disorder (OCD) patients, and are thought to reflect the activities of a hyperactive cortico-striatal circuit during action monitoring. We previously observed that obsessive-compulsive (OC) symptomatic students (non-patients) have larger ERNs during errors…

Two case studies of highly insoluble plutonium inhalation with implications for bioassay.

PubMed

Carbaugh, E H; La Bone, T R

2003-01-01

Two well characterised Pu inhalation cases show some remarkable similarities between substantially different types of Pu oxide. The circumstances of exposure, therapy, bioassay data, chemical solubility studies and dosimetry associated with these cases suggest that highly insoluble Pu may be more common than previously thought, and can pose significant challenges to bioassay programmes.

Two Case Studies of Highly Insoluble Plutonium Inhalation with Implications for Bioassay

DOE Office of Scientific and Technical Information (OSTI.GOV)

Carbaugh, Eugene H.; La Bone, Thomas R.

2003-01-01

Two well-characterized Pu inhalation cases show some remarkable similarities between substantially different types of Pu oxide. The circumstances of exposure, therapy, bioassay data, chemical solubility studies, and dosimetry associated with these cases suggests taht highly insoluble Pu may be more common than previously thought, and can pose significant challenges to bioassay programs.

Talking Pictures: Exploiting the Potential of Visual Sources to Generate Productive Pupil Talk

ERIC Educational Resources Information Center

Card, Jane

2012-01-01

Jane Card has long been fascinated by the power of visual sources to stimulate pupil thought and discussion. In previous articles she has shared insights from her own expert practice, fusing deep subject knowledge with careful planning to generate highly skilful questioning. Here she presents another rich example of classroom practice, carefully…

Women's Dominance with Men Revisited: What if She Is More Intelligent?

ERIC Educational Resources Information Center

Snodgrass, Sara E.; Stoliker, Howard

Previous research has indicated that women tend to relinquish leadership, or dominance, to men in mixed-sex interactions, even when the woman has a more dominant personality trait or when she is assigned to be the leader. This study was designed to determine effects of perceived intelligence in dominance, particularly if women who thought they…

Preschool Work against Bullying and Degrading Treatment: Experiences from an Action Learning Project

ERIC Educational Resources Information Center

Söderström, Åsa; Löfdahl Hultman, Annica

2017-01-01

This article deals with experiences from an action learning project against bullying and degrading treatment among nine Swedish preschools. Even though definitions of bullying and degrading treatment tend to lead to thoughts of school-age children rather than preschoolers, previous research shows that bullying occurs in preschool as well. Our data…

Responses on a Lateralized Lexical Decision Task Relate to both Reading Times and Comprehension

ERIC Educational Resources Information Center

Michael, Mary

2009-01-01

Research over the last few years has shown that the dominance of the left hemisphere in language processing is less complete than previously thought [Beeman, M. (1993). "Semantic processing in the right hemisphere may contribute to drawing inferences from discourse." "Brain and Language," 44, 80-120; Faust, M., & Chiarello, C. (1998). "Sentence…

Toward a Post-Constructivist Ethics in/of Teaching and Learning

ERIC Educational Resources Information Center

Roth, Wolff-Michael

2013-01-01

Constructivist epistemologies focus on ethics as a system of values in the mind--even when previously co-constructed in a social context--against which social agents compare the actions that they mentally plan before performing them. This approach is problematic, as it forces a wedge between thought and action, body and mind, universal and…

Internet: The Marketing Challenge of the Twentieth Century.

ERIC Educational Resources Information Center

Herbig, Paul; Hale, Brian

1997-01-01

Previously thought to be above commercial activity, the Internet is proving to be an outstanding marketing tool. This article examines linkage via World Wide Web, electronic mail, and news groups; argues that a home page is vital for the success of any business today; and tries to assess the impact of the Internet on the discipline of marketing.…

Chaos Modeling: Increasing Educational Researchers' Awareness of a New Tool.

ERIC Educational Resources Information Center

Bobner, Ronald F.; And Others

Chaos theory is being used as a tool to study a wide variety of phenomena. It is a philosophical and empirical approach that attempts to explain relationships previously thought to be totally random. Although some relationships are truly random, many data appear to be random but reveal repeatable patterns of behavior under further investigation.…

Parabacteroides distasonis attenuates colonic inflammation and prevents tumor formation in azoxymethane-treated high-fat diet-fed mice

USDA-ARS?s Scientific Manuscript database

Obesity is a major risk factor for colorectal cancer (CRC) and inflammation is thought to constitute one of the underlying mechanisms. We previously observed a depletion of Parabacteroides distasonis (PD) in the stool of tumor-bearing mice that was inversely related to the abundance of the pro-infla...

Using Music to Promote Children's Thinking and Enhance Their Literacy Development

ERIC Educational Resources Information Center

Salmon, Angela

2010-01-01

In an effort to understand how children's literacy is affected by their life experiences, this article analyses the natural disposition of children to engage in musical activities that connect them to previous experiences and allow them to build new thoughts. Music is inherent to children's experiences and is related to sounds heard everyday,…

From conscious thought to automatic action: A simulation account of action planning.

PubMed

Martiny-Huenger, Torsten; Martiny, Sarah E; Parks-Stamm, Elizabeth J; Pfeiffer, Elisa; Gollwitzer, Peter M

2017-10-01

We provide a theoretical framework and empirical evidence for how verbally planning an action creates direct perception-action links and behavioral automaticity. We argue that planning actions in an if (situation)-then (action) format induces sensorimotor simulations (i.e., activity patterns reenacting the event in the sensory and motor brain areas) of the anticipated situation and the intended action. Due to their temporal overlap, these activity patterns become linked. Whenever the previously simulated situation is encountered, the previously simulated action is partially reactivated through spreading activation and thus more likely to be executed. In 4 experiments (N = 363), we investigated the relation between specific if-then action plans worded to activate simulations of elbow flexion versus extension movements and actual elbow flexion versus extension movements in a subsequent, ostensibly unrelated categorization task. As expected, linking a critical stimulus to intended actions that implied elbow flexion movements (e.g., grabbing it for consumption) subsequently facilitated elbow flexion movements upon encountering the critical stimulus. However, linking a critical stimulus to actions that implied elbow extension movements (e.g., pointing at it) subsequently facilitated elbow extension movements upon encountering the critical stimulus. Thus, minor differences (i.e., exchanging the words "point at" with "grab") in verbally formulated action plans (i.e., conscious thought) had systematic consequences on subsequent actions. The question of how conscious thought can induce stimulus-triggered action is illuminated by the provided theoretical framework and the respective empirical evidence, facilitating the understanding of behavioral automaticity and human agency. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Symptomatic Remission and Counterfactual Reasoning in Schizophrenia.

PubMed

Albacete, Auria; Contreras, Fernando; Bosque, Clara; Gilabert, Ester; Albiach, Ángela; Menchón, José M

2016-01-01

Counterfactual thinking (CFT) is a type of conditional reasoning involving mental representations of alternatives to past factual events that previous preliminary research has suggested to be impaired in schizophrenia. However, despite the potential impact of these deficits on the functional outcome of these patients, studies examining the role of CFT in this disorder are still few in number. The present study aimed to extent previous results by evaluating CFT in the largest sample to date of schizophrenia patients in symptomatic remission and healthy controls. The relationship with symptomatology, illness duration, and sociodemographic characteristics was also explored. Methods: Seventy-eight schizophrenia patients and 84 healthy controls completed a series of tests that examined the generation of counterfactual thoughts, the influence of the "causal order effect," and the ability to counterfactually derive inferences by using de Counterfactual Inference Test. Results: Compared with controls, patients generated fewer counterfactual thoughts when faced with a simulated scenario. This deficit was negatively related to scores on all dimensions of the Positive and Negative Syndrome Scale-PANNS, as well as to longer illness duration. The results also showed that schizophrenia patients deviated significantly from the normative pattern when generating inferences from CFT. Conclusions: These findings reveal CFT impairment to be present in schizophrenia even when patients are in symptomatic remission. However, symptomatology and illness duration may have a negative influence on these patients' ability to generate counterfactual thoughts. The results might support the relevance of targeting CFT in future treatment approaches, although further research is needed to better describe the relationship between CFT and both symptomatology and functional outcome.

Symptomatic Remission and Counterfactual Reasoning in Schizophrenia

PubMed Central

Albacete, Auria; Contreras, Fernando; Bosque, Clara; Gilabert, Ester; Albiach, Ángela; Menchón, José M.

2017-01-01

Counterfactual thinking (CFT) is a type of conditional reasoning involving mental representations of alternatives to past factual events that previous preliminary research has suggested to be impaired in schizophrenia. However, despite the potential impact of these deficits on the functional outcome of these patients, studies examining the role of CFT in this disorder are still few in number. The present study aimed to extent previous results by evaluating CFT in the largest sample to date of schizophrenia patients in symptomatic remission and healthy controls. The relationship with symptomatology, illness duration, and sociodemographic characteristics was also explored. Methods: Seventy-eight schizophrenia patients and 84 healthy controls completed a series of tests that examined the generation of counterfactual thoughts, the influence of the “causal order effect,” and the ability to counterfactually derive inferences by using de Counterfactual Inference Test. Results: Compared with controls, patients generated fewer counterfactual thoughts when faced with a simulated scenario. This deficit was negatively related to scores on all dimensions of the Positive and Negative Syndrome Scale-PANNS, as well as to longer illness duration. The results also showed that schizophrenia patients deviated significantly from the normative pattern when generating inferences from CFT. Conclusions: These findings reveal CFT impairment to be present in schizophrenia even when patients are in symptomatic remission. However, symptomatology and illness duration may have a negative influence on these patients' ability to generate counterfactual thoughts. The results might support the relevance of targeting CFT in future treatment approaches, although further research is needed to better describe the relationship between CFT and both symptomatology and functional outcome. PMID:28111561

Protein kinases are associated with multiple, distinct cytoplasmic granules in quiescent yeast cells.

PubMed

Shah, Khyati H; Nostramo, Regina; Zhang, Bo; Varia, Sapna N; Klett, Bethany M; Herman, Paul K

2014-12-01

The cytoplasm of the eukaryotic cell is subdivided into distinct functional domains by the presence of a variety of membrane-bound organelles. The remaining aqueous space may be further partitioned by the regulated assembly of discrete ribonucleoprotein (RNP) complexes that contain particular proteins and messenger RNAs. These RNP granules are conserved structures whose importance is highlighted by studies linking them to human disorders like amyotrophic lateral sclerosis. However, relatively little is known about the diversity, composition, and physiological roles of these cytoplasmic structures. To begin to address these issues, we examined the cytoplasmic granules formed by a key set of signaling molecules, the protein kinases of the budding yeast Saccharomyces cerevisiae. Interestingly, a significant fraction of these proteins, almost 20%, was recruited to cytoplasmic foci specifically as cells entered into the G0-like quiescent state, stationary phase. Colocalization studies demonstrated that these foci corresponded to eight different granules, including four that had not been reported previously. All of these granules were found to rapidly disassemble upon the resumption of growth, and the presence of each was correlated with cell viability in the quiescent cultures. Finally, this work also identified new constituents of known RNP granules, including the well-characterized processing body and stress granule. The composition of these latter structures is therefore more varied than previously thought and could be an indicator of additional biological activities being associated with these complexes. Altogether, these observations indicate that quiescent yeast cells contain multiple distinct cytoplasmic granules that may make important contributions to their long-term survival. Copyright © 2014 by the Genetics Society of America.

TIDAL HEATING IN A MAGMA OCEAN WITHIN JUPITER’S MOON Io

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tyler, Robert H.; Henning, Wade G.; Hamilton, Christopher W., E-mail: robert.h.tyler@nasa.gov

Active volcanism observed on Io is thought to be driven by the temporally periodic, spatially differential projection of Jupiter's gravitational field over the moon. Previous theoretical estimates of the tidal heat have all treated Io as essentially a solid, with fluids addressed only through adjustment of rheological parameters rather than through appropriate extension of the dynamics. These previous estimates of the tidal response and associated heat generation on Io are therefore incomplete and possibly erroneous because dynamical aspects of the fluid behavior are not permitted in the modeling approach. Here we address this by modeling the partial-melt asthenosphere as amore » global layer of fluid governed by the Laplace Tidal Equations. Solutions for the tidal response are then compared with solutions obtained following the traditional solid-material approach. It is found that the tidal heat in the solid can match that of the average observed heat flux (nominally 2.25 W m{sup −2}), though only over a very restricted range of plausible parameters, and that the distribution of the solid tidal heat flux cannot readily explain a longitudinal shift in the observed (inferred) low-latitude heat fluxes. The tidal heat in the fluid reaches that observed over a wider range of plausible parameters, and can also readily provide the longitudinal offset. Finally, expected feedbacks and coupling between the solid/fluid tides are discussed. Most broadly, the results suggest that both solid and fluid tidal-response estimates must be considered in exoplanet studies, particularly where orbital migration under tidal dissipation is addressed.« less

The octopus genome and the evolution of cephalopod neural and morphological novelties.

PubMed

Albertin, Caroline B; Simakov, Oleg; Mitros, Therese; Wang, Z Yan; Pungor, Judit R; Edsinger-Gonzales, Eric; Brenner, Sydney; Ragsdale, Clifton W; Rokhsar, Daniel S

2015-08-13

Coleoid cephalopods (octopus, squid and cuttlefish) are active, resourceful predators with a rich behavioural repertoire. They have the largest nervous systems among the invertebrates and present other striking morphological innovations including camera-like eyes, prehensile arms, a highly derived early embryogenesis and a remarkably sophisticated adaptive colouration system. To investigate the molecular bases of cephalopod brain and body innovations, we sequenced the genome and multiple transcriptomes of the California two-spot octopus, Octopus bimaculoides. We found no evidence for hypothesized whole-genome duplications in the octopus lineage. The core developmental and neuronal gene repertoire of the octopus is broadly similar to that found across invertebrate bilaterians, except for massive expansions in two gene families previously thought to be uniquely enlarged in vertebrates: the protocadherins, which regulate neuronal development, and the C2H2 superfamily of zinc-finger transcription factors. Extensive messenger RNA editing generates transcript and protein diversity in genes involved in neural excitability, as previously described, as well as in genes participating in a broad range of other cellular functions. We identified hundreds of cephalopod-specific genes, many of which showed elevated expression levels in such specialized structures as the skin, the suckers and the nervous system. Finally, we found evidence for large-scale genomic rearrangements that are closely associated with transposable element expansions. Our analysis suggests that substantial expansion of a handful of gene families, along with extensive remodelling of genome linkage and repetitive content, played a critical role in the evolution of cephalopod morphological innovations, including their large and complex nervous systems.

Validating new summary indices for the Childhood Trauma Interview: associations with first onsets of major depressive disorder and anxiety disorders.

PubMed

Vrshek-Schallhorn, Suzanne; Wolitzky-Taylor, Kate; Doane, Leah D; Epstein, Alyssa; Sumner, Jennifer A; Mineka, Susan; Zinbarg, Richard E; Craske, Michelle G; Isaia, Ashley; Hammen, Constance; Adam, Emma K

2014-09-01

Childhood and adolescent adversity is of great interest in relation to risk for psychopathology, and interview measures of adversity are thought to be more reliable and valid than their questionnaire counterparts. One interview measure, the Childhood Trauma Interview (CTI; Fink et al., 1995), has been positively evaluated relative to similar measures, but there are some psychometric limitations to an existing scoring approach that limit the full potential of this measure. We propose several new summary indices for the CTI that permit examination of different types of adversity and different developmental periods. Our approach creates several summary indices: one sums the severity scores of adversities endorsed; another utilizes the number of minor and major (moderate to severe) adversities. The new indices were examined in association with first onsets of major depressive disorder (MDD) and anxiety disorders across a 5-year period using annual clinical diagnostic interviews (Structured Clinical Interview for DSM-IV-TR). Summary scores derived with the previously used approach were also examined for comparison. Data on 332 participants came from the Youth Emotion Project, a longitudinal study of risk for emotional disorders. Results support the predictive validity of the proposed summary scoring methods and indicate that several forms of major (but typically not minor) adversity are significantly associated with first onsets of MDD and anxiety disorders. Finally, multivariate regression models show that, in many instances, the new indices contributed significant unique variance predicting disorder onsets over and above the previously used summary indices. PsycINFO Database Record (c) 2014 APA, all rights reserved.

Factors associated with previously undiagnosed human immunodeficiency virus infection in a population of men who have sex with men and male-to-female transgender women in Lima, Peru.

PubMed

Billings, Joshua D; Joseph Davey, Dvora L; Konda, Kelika A; Bristow, Claire C; Chow, Jeremy; Klausner, Jeffrey D; Cáceres, Carlos F

2016-10-01

The aim of the study was to identify factors associated with undiagnosed human immunodeficiency virus (HIV) infection among men who have sex with men (MSM) and male-to-female transgender women in Lima, Peru.We analyzed characteristics of 378 MSM and transgender women recruited from 2 sexually transmitted infection (STI) clinics in Lima, Peru. Descriptive analyses compared: (A) HIV-uninfected, (B) previously undiagnosed HIV-infected, and (C) previously diagnosed HIV-infected participants. Multivariable logistic regression models identified: (1) correlates of previously undiagnosed HIV-infection among participants thought to be HIV-uninfected (B vs A); and (2) correlates of previously undiagnosed HIV-infection among HIV-infected participants (B vs C). Subanalysis identified correlates of frequent HIV testing among participants thought to be HIV-uninfected.Among participants, 31.0% were HIV-infected; of those, 35.0% were previously undiagnosed. Among participants thought to be HIV-uninfected (model 1), recent condomless receptive anal intercourse and last HIV test being over 1-year ago (compared to within the last 6-months) were associated with increased odds of being previously undiagnosed HIV-infected (adjusted odds ratio [aOR] = 2.43, 95% confidence interval [95%CI] = 1.10-5.36; aOR = 2.87, 95%CI = 1.10-7.53, respectively). Among HIV-infected participants (model 2), recent condomless receptive anal intercourse was again associated with previously undiagnosed HIV-infection (aOR = 2.54, 95%CI = 1.04-6.23). Achieving post-secondary education and prior syphilis infection were associated with lower odds of having previously undiagnosed HIV-infection (aOR = 0.35, 95%CI = 0.15-0.81; aOR = 0.32, 95%CI = 0.14-0.75, respectively).Reporting semiannual testing was associated with higher educational attainment, identifying as a transgender woman, or reporting a history of syphilis (aOR = 1.94, 95%CI = 1.11-3.37; aOR = 2.40, 95%CI = 1.23-4.70; aOR = 2.76, 95%CI = 1.62-4.71, respectively). Lower odds of semiannual testing were associated with recent condomless insertive anal intercourse or reporting a moderate or high self-perceived risk of acquiring HIV (aOR = 0.56, 95%CI = 0.33-0.96; aOR = 0.32, 95%CI = 0.18-0.59 and aOR = 0.43, 95%CI = 0.21-0.86, respectively).In our study, undiagnosed HIV-infection was associated with recent condomless receptive anal intercourse, infrequent HIV testing, lower education, and absence of prior syphilis diagnosis. Infrequent HIV testing was associated with lower education, not identifying as transgender, recent condomless insertive anal intercourse, absence of prior syphilis diagnosis, and higher self-perceived risk of HIV. Further efforts to decrease HIV transmission and increase HIV-serostatus awareness should be directed towards effectively promoting condom use and frequent HIV testing, integrated with STI management.

Electroencephalogram oscillations support the involvement of task-unrelated thoughts in the mechanism of boredom: A pilot study.

PubMed

Miyauchi, Eri; Kawasaki, Masahiro

2018-06-11

Boredom is a universal experience; however, the neural mechanisms underlying the phenomenon remain unclear. Previous research suggests that boredom is related to attentional failure and derives a possible explanation for the cognitive processes of boredom as a product of appraisals made about task-unrelated thoughts. There are little published data regarding proposed processes from neuroscientific perspectives. Therefore, the authors aimed to examine whether cognitive processes of boredom with task-unrelated thoughts followed by appraisals of them can be explained by examining oscillatory correlates. Electroencephalography was used to measure changes in neural oscillatory activity during subjective experiences of boredom or dislike in healthy subjects. Using this approach, temporal information of brain activity particular to the boredom experience was acquired. Additionally, the Adult Attention-Deficit Hyperactivity Disorder Self-Report Scale was used to evaluate the effects of attentional deficits in the neural processing of boredom. Tonic increase in theta and transient increases in alpha activity were exhibited before the key press response for experiencing boredom; however, only tonic increases in theta amplitudes were boredom specific. The results of this pilot study suggest that the boredom experience is possibly associated with cognitive processes involved in task-unrelated thoughts, followed by their appraisals to be bored, mediated by alpha and theta activity. Copyright © 2018 Elsevier B.V. All rights reserved.

How intention and monitoring your thoughts influence characteristics of autobiographical memories.

PubMed

Barzykowski, Krystian; Staugaard, Søren Risløv

2018-05-01

Involuntary autobiographical memories come to mind effortlessly and unintended, but the mechanisms of their retrieval are not fully understood. We hypothesize that involuntary retrieval depends on memories that are highly accessible (e.g., intense, unusual, recent, rehearsed), while the elaborate search that characterizes voluntary retrieval also produces memories that are mundane, repeated or distant - memories with low accessibility. Previous research provides some evidence for this 'threshold hypothesis'. However, in almost every prior study, participants have been instructed to report only memories while ignoring other thoughts. It is possible that such an instruction can modify the phenomenological characteristics of involuntary memories. This study aimed to investigate the effects of retrieval intentionality (i.e., wanting to retrieve a memory) and selective monitoring (i.e., instructions to report only memories) on the phenomenology of autobiographical memories. Participants were instructed to (1) intentionally retrieve autobiographical memories, (2) intentionally retrieve any type of thought (3) wait for an autobiographical memory to spontaneously appear, or (4) wait for any type of thought to spontaneously appear. They rated the mental content on a number of phenomenological characteristics both during retrieval and retrospectively following retrieval. The results support the prediction that highly accessible memories mostly enter awareness unintended and without selective monitoring, while memories with low accessibility rely on intention and selective monitoring. We discuss the implications of these effects. © 2017 The British Psychological Society.

A cognitive movement scientist's view on the link between thought and action: insights from the "Badische Zimmer" metaphor.

PubMed

Hossner, Ernst-Joachim

2009-01-01

The problem of a bidirectional link between thought and action is approached from the perspective of cognitive movement science. The metaphor of the "Badische Zimmer" - an adaptation of Searle's Chinese room metaphor - is used to illustrate shortcomings in the classical conception of linear information processing and to introduce some features which current theories of movement control and learning should embrace. On this basis, the case is made for a return to an ideomotor view of motor control and learning based on effect prediction (E') as a function of the situational context (S') and one's own motor responses (R'). The relevance of the derived concept of sensorimotor chains linking elementary S'R'E' units in the course of motor learning is finally discussed with respect to potential implications for an integrative theory of perception, action, and decision making.

Powerful postures versus powerful roles: which is the proximate correlate of thought and behavior?

PubMed

Huang, Li; Galinsky, Adam D; Gruenfeld, Deborah H; Guillory, Lucia E

2011-01-01

Three experiments explored whether hierarchical role and body posture have independent or interactive effects on the main outcomes associated with power: action in behavior and abstraction in thought. Although past research has found that being in a powerful role and adopting an expansive body posture can each enhance a sense of power, two experiments showed that when individuals were placed in high- or low-power roles while adopting an expansive or constricted posture, only posture affected the implicit activation of power, the taking of action, and abstraction. However, even though role had a smaller effect on the downstream consequences of power, it had a stronger effect than posture on self-reported sense of power. A final experiment found that posture also had a larger effect on action than recalling an experience of high or low power. We discuss body postures as one of the most proximate correlates of the manifestations of power.

Bohrian Complementarity in the Light of Kantian Teleology

NASA Astrophysics Data System (ADS)

Pringe, Hernán

2014-03-01

The Kantian influences on Bohr's thought and the relationship between the perspective of complementarity in physics and in biology seem at first sight completely unrelated issues. However, the goal of this work is to show their intimate connection. We shall see that Bohr's views on biology shed light on Kantian elements of his thought, which enables a better understanding of his complementary interpretation of quantum theory. For this purpose, we shall begin by discussing Bohr's views on the analogies concerning the epistemological situation in biology and in physics. Later, we shall compare the Bohrian and the Kantian approaches to the science of life in order to show their close connection. On this basis, we shall finally turn to the issue of complementarity in quantum theory in order to assess what we can learn about the epistemological problems in the quantum realm from a consideration of Kant's views on teleology.

Quality quandaries: Understanding aspects influencing different types of multiple response optimization

DOE Office of Scientific and Technical Information (OSTI.GOV)

Anderson-Cook, Christine M.; Cao, Yongtao; Lu, Lu

In this study, optimizing with several responses can benefit from an objective approach of eliminating non-contenders, understanding trade-offs between competing responses, and then identifying a final choice that matches optimization priorities. To offer insights that help guide thoughtful decisions, we explore and summarize different patterns of solution sets and their trade-offs for different types of optimization with responses that are to be maximized and/or to achieve a target.

Quality quandaries: Understanding aspects influencing different types of multiple response optimization

DOE PAGES

Anderson-Cook, Christine M.; Cao, Yongtao; Lu, Lu

2016-08-26

In this study, optimizing with several responses can benefit from an objective approach of eliminating non-contenders, understanding trade-offs between competing responses, and then identifying a final choice that matches optimization priorities. To offer insights that help guide thoughtful decisions, we explore and summarize different patterns of solution sets and their trade-offs for different types of optimization with responses that are to be maximized and/or to achieve a target.

Fractal astronomy.

NASA Astrophysics Data System (ADS)

Beech, M.

1989-02-01

The author discusses some of the more recent research on fractal astronomy and results presented in several astronomical studies. First, the large-scale structure of the universe is considered, while in another section one drops in scale to examine some of the smallest bodies in our solar system; the comets and meteoroids. The final section presents some thoughts on what influence the fractal ideology might have on astronomy, focusing particularly on the question recently raised by Kadanoff, "Fractals: where's the physics?"

Research and Development Project to Develop, Improve, Expand and Evaluate Behavioral Goals of a Team-Taught, Humanities-Oriented Course in World Civilization for Ninth and Tenth Grade Students. Final Report.

ERIC Educational Resources Information Center

Fairfax County School Board, VA.

This report describes five out of seventeen units in a World Civilization program, a two-year humanities oriented interdisciplinary English and social studies program. Course material focuses on those records of man which represent his thoughts and feelings about life. History serves as the basis for the chronological development of the course,…

Buried Object Detection

DTIC Science & Technology

1988-01-22

Final Report 19 January 1987 Army Research OfficeM Contract No. DAAL03..87-K-0052 National Center for Physical Acoustics D T ! C " Naioal P. 0. Box 847...black . umberJ FIELO I GROUP I SU9GROU-p Acoustic , Seismic, Acoustic seismic coupling, porefluid, pulse echo, propagation, soils, sound speed...seismic transfer function. /’An acoustic scheme for buried object detection is thought to involve a sound source above the ground and a microphone as a

Proceedings of the 1990 Annual Meeting of the Association for Education in Journalism and Mass Communication (73rd, Minneapolis, Minnesota, August 1-4, 1990). Part X: Journalism History Studies.

ERIC Educational Resources Information Center

Association for Education in Journalism and Mass Communication.

The journalism section of the proceedings includes the following 18 papers: "A Newspaper Legacy: E. W. Scripps' Thoughts on Journalism in His Final Years" (Ted Pease); "The Great War of Words between the United States and Mexico: Public and Private Communications of the U.S. Government during World War I" (Robert Pennington);…

Legionnaire's disease associated with acute encephalitis and arrhythmia.

PubMed

Karim, Anita; Ahmed, Shahid; Rossoff, Leonard J

2002-05-01

To report an unusual, life-threatening combination of neurologic, cardiac, and gastrointestinal symptoms in the presence of a community-acquired pneumonia. Case report. University hospital. Previously healthy young male. Diagnostic fiberoptic bronchoscopy, lumber puncture, magnetic resonance imaging of the brain, and institution of systemic antibiotics. Gradual clinical improvement of a multiple-system illness. Legionellosis should be considered in the differential diagnosis of patients presenting with neurologic, cardiac, and gastrointestinal symptoms, particularly in the presence of radiographic pneumonia. Furthermore, Legionella meningoencephalitis may present with findings on magnetic resonance imaging previously thought to be characteristic of herpes encephalitis.

From Shattered Assumptions to Weakened Worldviews: Trauma Symptoms Signal Anxiety Buffer Disruption

PubMed Central

Edmondson, Donald; Chaudoir, Stephenie R.; Mills, Mary Alice; Park, Crystal L.; Holub, Julie; Bartkowiak, Jennifer M.

2013-01-01

The fundamental assertion of worldview-based models of posttraumatic stress disorder is that trauma symptoms result when traumatic experiences cannot be readily assimilated into previously held worldviews. In two studies, we test the anxiety buffer disruption hypothesis, which states that trauma symptoms result from the disruption of normal death anxiety-buffering functions of worldview. In Study 1, participants with trauma symptoms greater than the cutoff for PTSD evinced greater death-thought accessibility than those with sub-clinical or negligible symptoms after a reminder of death. In Study 2, participants with clinically significant trauma symptoms showed no evidence of worldview defense though death-thoughts were accessible. These results support the anxiety buffer disruption hypothesis, and suggest an entirely new approach to experimental PTSD research. PMID:24077677

Yeast and bacterial diversity along a transect in an acidic, As-Fe rich environment revealed by cultural approaches.

PubMed

Delavat, François; Lett, Marie-Claire; Lièvremont, Didier

2013-10-01

Acid mine drainages (AMDs) are often thought to harbour low biodiversity, yet little is known about the diversity distribution along the drainages. Using culture-dependent approaches, the microbial diversity from the Carnoulès AMD sediment was investigated for the first time along a transect showing progressive environmental stringency decrease. In total, 20 bacterial genera were detected, highlighting a higher bacterial diversity than previously thought. Moreover, this approach led to the discovery of 16 yeast species, demonstrating for the first time the presence of this important phylogenetic group in this AMD. All in all, the location of the microbes along the transect helps to better understand their distribution in a pollution gradient. Copyright © 2013 Elsevier B.V. All rights reserved.

Final efficacy and updated safety results of the randomized phase III BEATRICE trial evaluating adjuvant bevacizumab-containing therapy in triple-negative early breast cancer.

PubMed

Bell, R; Brown, J; Parmar, M; Toi, M; Suter, T; Steger, G G; Pivot, X; Mackey, J; Jackisch, C; Dent, R; Hall, P; Xu, N; Morales, L; Provencher, L; Hegg, R; Vanlemmens, L; Kirsch, A; Schneeweiss, A; Masuda, N; Overkamp, F; Cameron, D

2017-04-01

The purpose of this analysis was to assess the long-term impact of adding bevacizumab to adjuvant chemotherapy for early triple-negative breast cancer (TNBC). Patients eligible for the open-label randomized phase III BEATRICE trial had centrally confirmed triple-negative operable primary invasive breast cancer (pT1a-pT3). Investigators selected anthracycline- and/or taxane-based chemotherapy for each patient. After definitive surgery, patients were randomized 1:1 to receive ≥4 cycles of chemotherapy alone or with 1 year of bevacizumab (5 mg/kg/week equivalent). Stratification factors were nodal status, selected chemotherapy, hormone receptor status, and type of surgery. The primary end point was invasive disease-free survival (IDFS; previously reported). Secondary outcome measures included overall survival (OS) and safety. After 56 months' median follow-up, 293 of 2591 randomized patients had died. There was no statistically significant difference in OS between treatment arms in either the total population (hazard ratio 0.93, 95% confidence interval [CI] 0.74-1.17; P = 0.52) or pre-specified subgroups. The 5-year OS rate was 88% (95% CI 86-90%) in both treatment arms. Updated IDFS results were consistent with the primary IDFS analysis. Five-year IDFS rates were 77% (95% CI 75-79%) with chemotherapy alone versus 80% (95% CI 77-82%) with bevacizumab. From 18 months after first study dose to study end, new grade ≥3 adverse events occurred in 4.6% and 4.5% of patients in the two arms, respectively. Final OS results showed no significant benefit from bevacizumab therapy for early TNBC. Late-onset toxicities were rare in both groups. Five-year OS and IDFS rates suggest that the prognosis for patients with TNBC is better than previously thought. NCT00528567. © The Author 2016. Published by Oxford University Press on behalf of the European Society for Medical Oncology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Measuring functional connectivity using MEG: Methodology and comparison with fcMRI

PubMed Central

Brookes, Matthew J.; Hale, Joanne R.; Zumer, Johanna M.; Stevenson, Claire M.; Francis, Susan T.; Barnes, Gareth R.; Owen, Julia P.; Morris, Peter G.; Nagarajan, Srikantan S.

2011-01-01

Functional connectivity (FC) between brain regions is thought to be central to the way in which the brain processes information. Abnormal connectivity is thought to be implicated in a number of diseases. The ability to study FC is therefore a key goal for neuroimaging. Functional connectivity (fc) MRI has become a popular tool to make connectivity measurements but the technique is limited by its indirect nature. A multimodal approach is therefore an attractive means to investigate the electrodynamic mechanisms underlying hemodynamic connectivity. In this paper, we investigate resting state FC using fcMRI and magnetoencephalography (MEG). In fcMRI, we exploit the advantages afforded by ultra high magnetic field. In MEG we apply envelope correlation and coherence techniques to source space projected MEG signals. We show that beamforming provides an excellent means to measure FC in source space using MEG data. However, care must be taken when interpreting these measurements since cross talk between voxels in source space can potentially lead to spurious connectivity and this must be taken into account in all studies of this type. We show good spatial agreement between FC measured independently using MEG and fcMRI; FC between sensorimotor cortices was observed using both modalities, with the best spatial agreement when MEG data are filtered into the β band. This finding helps to reduce the potential confounds associated with each modality alone: while it helps reduce the uncertainties in spatial patterns generated by MEG (brought about by the ill posed inverse problem), addition of electrodynamic metric confirms the neural basis of fcMRI measurements. Finally, we show that multiple MEG based FC metrics allow the potential to move beyond what is possible using fcMRI, and investigate the nature of electrodynamic connectivity. Our results extend those from previous studies and add weight to the argument that neural oscillations are intimately related to functional connectivity and the BOLD response. PMID:21352925